MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 SUPERFAMILY SSF48452 336 365 9.1E-84 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 SUPERFAMILY SSF48452 22 301 9.1E-84 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 SUPERFAMILY SSF48452 407 583 9.1E-84 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 PANTHER PTHR35148 368 587 1.5E-15 T 22-04-2016 MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 PANTHER PTHR35148 39 298 1.5E-15 T 22-04-2016 MED134_RS12200 690adeab63c06af26486a10f81a072e8 596 Pfam PF12771 Starch-binding associating with outer membrane 105 294 6.3E-11 T 22-04-2016 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 156 3.6E-18 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 PANTHER PTHR32552 12 679 4.6E-95 T 22-04-2016 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 SUPERFAMILY SSF56935 28 679 7.63E-108 T 22-04-2016 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 Gene3D G3DSA:2.170.130.10 28 157 5.4E-25 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 Gene3D G3DSA:2.40.170.20 158 679 1.4E-88 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 Pfam PF00593 TonB dependent receptor 427 675 4.8E-27 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10905 8a29edae715be2ea3cc5ce8da8830388 679 PANTHER PTHR32552:SF13 12 679 4.6E-95 T 22-04-2016 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 SUPERFAMILY SSF56601 238 579 6.8E-83 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 SMART SM00740 605 663 1.8E-10 T 22-04-2016 IPR005543 PASTA domain MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 Pfam PF03793 PASTA domain 610 663 5.1E-13 T 22-04-2016 IPR005543 PASTA domain MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 Gene3D G3DSA:3.40.710.10 245 577 2.3E-81 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 SUPERFAMILY SSF56519 51 235 3.79E-22 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 Pfam PF03717 Penicillin-binding Protein dimerisation domain 55 216 1.5E-9 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 PANTHER PTHR30627:SF1 2 614 4.5E-122 T 22-04-2016 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 SUPERFAMILY SSF54184 607 660 1.23E-11 T 22-04-2016 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 Gene3D G3DSA:3.90.1310.10 156 244 2.7E-16 T 22-04-2016 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 570 4.3E-55 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MED134_RS12505 2aa270344e1ba1045aff9eb47409e71a 663 PANTHER PTHR30627 2 614 4.5E-122 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 SUPERFAMILY SSF55031 221 328 2.22E-28 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 Gene3D G3DSA:3.30.70.360 217 334 3.3E-33 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 SUPERFAMILY SSF53187 28 233 3.89E-84 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 SUPERFAMILY SSF53187 335 424 3.89E-84 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 37 412 1.7E-108 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 Pfam PF01546 Peptidase family M20/M25/M40 94 419 2.3E-34 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 PANTHER PTHR11014:SF63 26 426 6.7E-142 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 PANTHER PTHR11014 26 426 6.7E-142 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 PIRSF PIRSF005962 20 426 2.1E-121 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 Pfam PF07687 Peptidase dimerisation domain 222 320 5.0E-12 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 Gene3D G3DSA:3.40.630.10 20 214 9.1E-101 T 22-04-2016 MED134_RS02105 8fa0cc92102ffc22632f9a533c259a31 426 Gene3D G3DSA:3.40.630.10 335 425 9.1E-101 T 22-04-2016 MED134_RS11080 752a74b7bf390f7f88d46b50ba3187fb 239 PANTHER PTHR10859 4 225 6.3E-53 T 22-04-2016 MED134_RS11080 752a74b7bf390f7f88d46b50ba3187fb 239 Gene3D G3DSA:3.90.550.10 3 153 8.2E-21 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11080 752a74b7bf390f7f88d46b50ba3187fb 239 PANTHER PTHR10859:SF49 4 225 6.3E-53 T 22-04-2016 MED134_RS11080 752a74b7bf390f7f88d46b50ba3187fb 239 Pfam PF00535 Glycosyl transferase family 2 6 138 1.7E-23 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS11080 752a74b7bf390f7f88d46b50ba3187fb 239 SUPERFAMILY SSF53448 3 221 1.69E-31 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Gene3D G3DSA:2.130.10.10 221 374 2.1E-7 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Pfam PF13620 Carboxypeptidase regulatory-like domain 439 503 1.3E-7 T 22-04-2016 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 PANTHER PTHR30128 532 651 5.2E-27 T 22-04-2016 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 SUPERFAMILY SSF82171 194 375 2.75E-10 T 22-04-2016 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 SUPERFAMILY SSF48452 42 133 3.37E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 PRINTS PR01021 OMPA domain signature 589 605 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 PRINTS PR01021 OMPA domain signature 544 566 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 PRINTS PR01021 OMPA domain signature 574 589 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Pfam PF07676 WD40-like Beta Propeller Repeat 336 370 1.3E-4 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 SUPERFAMILY SSF103088 527 650 5.23E-26 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Gene3D G3DSA:1.25.40.10 31 120 4.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Pfam PF00691 OmpA family 543 631 2.3E-12 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Gene3D G3DSA:3.30.1330.60 540 651 9.7E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 Gene3D G3DSA:2.60.40.10 438 507 2.0E-6 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS07335 97f56496a8127c30f409d148d751a1c5 653 SUPERFAMILY SSF49478 439 502 1.45E-5 T 22-04-2016 MED134_RS03980 b9725eb8f8ca67333e909653f289c1f3 219 SUPERFAMILY SSF53955 72 196 9.75E-6 T 22-04-2016 IPR023346 Lysozyme-like domain MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 PANTHER PTHR30349 132 334 8.5E-23 T 22-04-2016 MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 PANTHER PTHR30349 357 413 8.5E-23 T 22-04-2016 MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 Gene3D G3DSA:1.10.443.10 232 401 5.8E-18 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 Pfam PF00589 Phage integrase family 259 400 3.6E-8 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 SUPERFAMILY SSF56349 117 408 3.83E-29 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 Gene3D G3DSA:1.10.150.130 132 212 2.8E-4 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal MED134_RS00490 42711405724f9b809c8d949498ce0f67 414 Pfam PF13102 Phage integrase SAM-like domain 8 178 5.9E-7 T 22-04-2016 IPR025269 Phage integrase SAM-like domain MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PANTHER PTHR10520 3 277 4.7E-131 T 22-04-2016 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 SUPERFAMILY SSF55021 3 83 1.21E-10 T 22-04-2016 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 SUPERFAMILY SSF53328 88 284 6.93E-61 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 283 1.2E-112 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PANTHER PTHR10520:SF7 3 277 4.7E-131 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 Gene3D G3DSA:3.30.70.260 1 83 7.3E-16 T 22-04-2016 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 283 44.419 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PIRSF PIRSF036480 1 284 2.5E-114 T 22-04-2016 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 3.4E-54 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 Pfam PF00551 Formyl transferase 89 265 1.8E-41 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS03740 467afe62be79969cdbb5a409106b36e3 284 Gene3D G3DSA:3.40.50.170 87 279 4.0E-59 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 Pfam PF00263 Bacterial type II and III secretion system protein 552 719 3.3E-36 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 PANTHER PTHR30332 420 719 1.4E-40 T 22-04-2016 MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 PRINTS PR00811 Bacterial general secretion pathway protein D signature 684 702 6.9E-14 T 22-04-2016 IPR001775 GspD/PilQ family MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 PRINTS PR00811 Bacterial general secretion pathway protein D signature 707 720 6.9E-14 T 22-04-2016 IPR001775 GspD/PilQ family MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 PRINTS PR00811 Bacterial general secretion pathway protein D signature 548 572 6.9E-14 T 22-04-2016 IPR001775 GspD/PilQ family MED134_RS08360 88d5e656661cd3d834859d72e65bcde8 720 PRINTS PR00811 Bacterial general secretion pathway protein D signature 476 486 6.9E-14 T 22-04-2016 IPR001775 GspD/PilQ family MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 SUPERFAMILY SSF51161 33 318 1.1E-78 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 4 327 34.351 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 224 259 2.9E-5 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 260 295 2.1E-6 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 144 7.4E-8 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 146 180 1.0E-5 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Gene3D G3DSA:2.160.10.10 122 307 7.9E-47 T 22-04-2016 MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 328 2.3E-106 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 PANTHER PTHR22572 84 297 1.8E-54 T 22-04-2016 MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 PANTHER PTHR22572:SF117 84 297 1.8E-54 T 22-04-2016 MED134_RS02515 9ea677a7b37031667f117c3a34a7f240 341 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 89 1.3E-19 T 22-04-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Gene3D G3DSA:2.40.30.10 316 415 3.6E-35 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Gene3D G3DSA:3.30.70.870 416 491 5.6E-37 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Pfam PF00679 Elongation factor G C-terminus 612 698 1.2E-28 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Pfam PF00009 Elongation factor Tu GTP binding domain 8 293 9.7E-65 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SUPERFAMILY SSF54980 413 491 2.34E-24 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SUPERFAMILY SSF54980 615 701 7.19E-28 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Gene3D G3DSA:3.30.70.240 610 704 2.2E-31 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Pfam PF14492 Elongation Factor G, domain II 415 488 5.7E-33 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 49 64 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SUPERFAMILY SSF52540 4 293 2.76E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SMART SM00889 491 610 1.9E-54 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SMART SM00838 612 699 3.3E-48 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Hamap MF_00054_B Elongation factor G [fusA]. 4 703 103.255 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 4 704 0.0 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Pfam PF03144 Elongation factor Tu domain 2 335 401 1.8E-13 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SUPERFAMILY SSF54211 490 610 1.69E-35 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS12225 7473b73070928719474de360ec41c6b8 708 SUPERFAMILY SSF50447 276 415 2.2E-34 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS12225 7473b73070928719474de360ec41c6b8 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 191 2.9E-31 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Gene3D G3DSA:3.30.230.10 495 609 1.1E-41 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Gene3D G3DSA:3.40.50.300 3 297 2.2E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PRINTS PR00315 GTP-binding elongation factor signature 10 23 4.74E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PRINTS PR00315 GTP-binding elongation factor signature 105 116 4.74E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PRINTS PR00315 GTP-binding elongation factor signature 141 150 4.74E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PRINTS PR00315 GTP-binding elongation factor signature 56 64 4.74E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PRINTS PR00315 GTP-binding elongation factor signature 89 99 4.74E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115 266 294 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115 1 188 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115 314 703 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115:SF66 266 294 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115:SF66 1 188 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 PANTHER PTHR23115:SF66 314 703 0.0 T 22-04-2016 MED134_RS12225 7473b73070928719474de360ec41c6b8 708 Pfam PF03764 Elongation factor G, domain IV 490 610 3.0E-39 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PANTHER PTHR30612 466 1086 0.0 T 22-04-2016 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PANTHER PTHR30612 110 124 0.0 T 22-04-2016 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PANTHER PTHR30612 170 392 0.0 T 22-04-2016 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PANTHER PTHR30612 7 68 0.0 T 22-04-2016 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF52540 596 769 2.13E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF81886 946 1029 3.92E-54 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF81886 771 899 3.92E-54 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SMART SM00957 8 582 9.6E-232 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Pfam PF07517 SecA DEAD-like domain 9 582 1.4E-121 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.40.50.300 597 770 1.6E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SMART SM00958 410 538 1.9E-30 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Pfam PF01043 SecA preprotein cross-linking domain 398 538 4.1E-37 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 89 696 3.1E-197 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF52540 548 595 3.84E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF52540 13 59 3.84E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.40.50.300 6 64 1.5E-115 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.40.50.300 169 319 1.5E-115 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.40.50.300 105 123 1.5E-115 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.40.50.300 549 596 1.5E-115 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF52540 142 319 3.84E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:1.10.3060.10 799 897 1.2E-42 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:1.10.3060.10 940 1019 1.2E-42 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.90.1440.10 480 547 3.4E-39 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Gene3D G3DSA:3.90.1440.10 403 448 3.4E-39 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Pfam PF07516 SecA Wing and Scaffold domain 769 1017 3.3E-55 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 ProSitePatterns PS01312 SecA family signature. 680 695 - T 22-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PRINTS PR00906 SecA protein signature 519 541 1.4E-34 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PRINTS PR00906 SecA protein signature 593 606 1.4E-34 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PRINTS PR00906 SecA protein signature 556 573 1.4E-34 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 PRINTS PR00906 SecA protein signature 108 132 1.4E-34 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF81767 482 547 8.24E-31 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 SUPERFAMILY SSF81767 405 450 8.24E-31 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MED134_RS13305 20f9f2ea3407e6dab4dc28d3b5d077f9 1120 Hamap MF_01382 Protein translocase subunit SecA [secA]. 7 1021 19.469 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 7.5E-13 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 227 241 7.5E-13 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 197 213 7.5E-13 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PANTHER PTHR30195:SF10 10 691 9.1E-253 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PANTHER PTHR30195:SF10 719 809 9.1E-253 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 SUPERFAMILY SSF53335 80 573 4.46E-114 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00520 a749b5af46c84759995c7a742350b165 809 SUPERFAMILY SSF53335 7 47 4.46E-114 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00520 a749b5af46c84759995c7a742350b165 809 Pfam PF02384 N-6 DNA Methylase 177 485 7.1E-61 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 Gene3D G3DSA:3.40.50.150 199 467 1.9E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PANTHER PTHR30195 10 691 9.1E-253 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 PANTHER PTHR30195 719 809 9.1E-253 T 22-04-2016 MED134_RS00520 a749b5af46c84759995c7a742350b165 809 Pfam PF12161 HsdM N-terminal domain 10 149 1.0E-19 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 Pfam PF00467 KOW motif 134 165 2.4E-6 T 22-04-2016 IPR005824 KOW MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 SUPERFAMILY SSF50104 129 184 7.31E-18 T 22-04-2016 IPR008991 Translation protein SH3-like domain MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 10 184 7.6E-55 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 Gene3D G3DSA:3.30.70.940 8 119 3.3E-36 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 SMART SM00738 7 117 4.1E-31 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 SMART SM00739 130 157 5.2E-5 T 22-04-2016 IPR005824 KOW MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 SUPERFAMILY SSF82679 8 118 5.36E-32 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 7 184 22.526 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 PRINTS PR00338 Transcription termination factor NUSG signature 62 74 3.9E-16 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 PRINTS PR00338 Transcription termination factor NUSG signature 160 176 3.9E-16 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 PRINTS PR00338 Transcription termination factor NUSG signature 142 157 3.9E-16 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 Gene3D G3DSA:2.30.30.30 124 184 2.5E-27 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 Pfam PF02357 Transcription termination factor nusG 8 114 8.3E-21 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 MED134_RS04910 ef5b613f3b65260800fb4bd9cd6c77d2 184 PANTHER PTHR30265 8 184 4.7E-55 T 22-04-2016 MED134_RS11830 7d81f9834b3741fa75d7714e6e84f80d 169 Gene3D G3DSA:3.10.450.50 36 152 1.7E-10 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS11830 7d81f9834b3741fa75d7714e6e84f80d 169 Pfam PF12893 Putative lumazine-binding 37 152 8.6E-7 T 22-04-2016 MED134_RS11830 7d81f9834b3741fa75d7714e6e84f80d 169 SUPERFAMILY SSF54427 36 159 2.19E-20 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 PIRSF PIRSF000124 4 421 2.1E-55 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 SUPERFAMILY SSF52413 305 418 1.14E-26 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 SUPERFAMILY SSF48179 206 297 3.91E-23 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 SMART SM00984 322 419 1.3E-25 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 Gene3D G3DSA:3.40.50.720 2 227 3.9E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 Gene3D G3DSA:3.40.50.720 237 418 2.1E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 414 4.4E-119 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 PANTHER PTHR11374 1 417 8.2E-206 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 182 1.9E-33 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 207 295 3.2E-22 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 PIRSF PIRSF500136 1 424 2.4E-147 T 22-04-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 SUPERFAMILY SSF51735 5 196 6.36E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 PANTHER PTHR11374:SF25 1 417 8.2E-206 T 22-04-2016 MED134_RS01335 8de55be70c0e68314bda0dac349fa7ee 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 417 2.2E-18 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 SUPERFAMILY SSF52954 366 459 3.93E-20 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 PANTHER PTHR11476 97 460 2.9E-178 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 PANTHER PTHR11476 4 73 2.9E-178 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 SUPERFAMILY SSF55681 5 357 7.37E-71 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 PANTHER PTHR11476:SF1 97 460 2.9E-178 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 PANTHER PTHR11476:SF1 4 73 2.9E-178 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Gene3D G3DSA:3.30.930.10 3 214 7.0E-106 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Gene3D G3DSA:3.30.930.10 266 361 7.0E-106 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 451 5.8E-117 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 PIRSF PIRSF001549 1 460 2.8E-127 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Pfam PF03129 Anticodon binding domain 373 460 4.2E-12 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Pfam PF13393 Histidyl-tRNA synthetase 98 349 8.0E-28 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Pfam PF13393 Histidyl-tRNA synthetase 10 69 9.8E-7 T 22-04-2016 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 458 26.038 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 MED134_RS02745 df5fe1382e058f19af24ec0e42bb7c36 460 Gene3D G3DSA:3.40.50.800 364 460 4.1E-26 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 PANTHER PTHR27000 8 244 1.2E-61 T 22-04-2016 MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 Pfam PF00560 Leucine Rich Repeat 135 157 0.44 T 22-04-2016 IPR001611 Leucine-rich repeat GO:0005515 MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 Pfam PF13855 Leucine rich repeat 67 122 8.1E-7 T 22-04-2016 IPR001611 Leucine-rich repeat GO:0005515 MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 SUPERFAMILY SSF52058 39 244 3.57E-41 T 22-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 Gene3D G3DSA:3.80.10.10 35 244 4.0E-49 T 22-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like MED134_RS03650 edd44f87e6fc5099dd09bd15e9fe56d3 253 Pfam PF13516 Leucine Rich repeat 181 197 1.7 T 22-04-2016 IPR001611 Leucine-rich repeat GO:0005515 MED134_RS00650 3b58c6d6007071cad15a21435486c8af 412 Pfam PF13440 Polysaccharide biosynthesis protein 36 331 8.8E-10 T 22-04-2016 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 SMART SM00342 259 343 2.3E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 Pfam PF12833 Helix-turn-helix domain 265 343 5.2E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 PANTHER PTHR11019:SF50 241 351 5.6E-19 T 22-04-2016 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 SUPERFAMILY SSF46689 295 345 1.75E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 Gene3D G3DSA:1.10.10.60 294 345 5.7E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 296 339 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS03785 8712692cc09880684675d2bc41ea461b 352 PANTHER PTHR11019 241 351 5.6E-19 T 22-04-2016 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 PIRSF PIRSF006603 11 446 6.6E-75 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 PANTHER PTHR11206:SF153 6 439 6.8E-111 T 22-04-2016 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 PANTHER PTHR11206 6 439 6.8E-111 T 22-04-2016 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 Pfam PF01554 MatE 245 405 3.7E-26 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 Pfam PF01554 MatE 19 178 2.5E-30 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS13250 4ad37858fe535cf8ccffb2e30787ff37 448 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 419 7.1E-84 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PANTHER PTHR22912:SF48 4 312 4.4E-138 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PANTHER PTHR22912 4 312 4.4E-138 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 SUPERFAMILY SSF51905 3 309 3.56E-51 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 Gene3D G3DSA:3.50.50.60 5 113 5.1E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 309 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 8.0E-75 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 Gene3D G3DSA:3.50.50.60 114 303 1.1E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 309 5.9E-111 T 22-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.5E-36 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.5E-36 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 2.5E-36 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 2.5E-36 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.5E-36 T 22-04-2016 MED134_RS05350 8b45d3179080fe7d8a1c9157043e7000 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 298 1.4E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS03455 6a0ac00a424a376daaa0833165e0e0f5 357 Gene3D G3DSA:3.90.70.10 123 336 1.2E-31 T 22-04-2016 MED134_RS03455 6a0ac00a424a376daaa0833165e0e0f5 357 SMART SM00645 126 345 0.0035 T 22-04-2016 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 MED134_RS03455 6a0ac00a424a376daaa0833165e0e0f5 357 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 296 306 - T 22-04-2016 IPR025660 Cysteine peptidase, histidine active site MED134_RS03455 6a0ac00a424a376daaa0833165e0e0f5 357 SUPERFAMILY SSF54001 117 333 8.42E-33 T 22-04-2016 MED134_RS03455 6a0ac00a424a376daaa0833165e0e0f5 357 Pfam PF00112 Papain family cysteine protease 132 332 7.4E-14 T 22-04-2016 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 SUPERFAMILY SSF51556 77 386 6.81E-105 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 Gene3D G3DSA:2.30.40.10 19 78 5.7E-27 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 Gene3D G3DSA:2.30.40.10 386 425 5.7E-27 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 PANTHER PTHR11271:SF33 29 425 1.2E-98 T 22-04-2016 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 Pfam PF01979 Amidohydrolase family 73 420 1.2E-48 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 SUPERFAMILY SSF51338 34 86 9.79E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 Gene3D G3DSA:3.20.20.140 79 382 2.4E-92 T 22-04-2016 MED134_RS07310 2963b8c6a09097e8f8ca9426d06e9cc5 425 PANTHER PTHR11271 29 425 1.2E-98 T 22-04-2016 MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 SUPERFAMILY SSF52540 73 358 6.35E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 PANTHER PTHR24031:SF0 1 425 6.7E-188 T 22-04-2016 MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 Pfam PF00271 Helicase conserved C-terminal domain 230 338 3.9E-27 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 Gene3D G3DSA:3.40.50.300 211 372 8.6E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 SMART SM00490 257 338 4.3E-31 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 Pfam PF00270 DEAD/DEAH box helicase 26 195 6.1E-53 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 Gene3D G3DSA:3.40.50.300 1 210 9.0E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 SMART SM00487 20 221 4.0E-61 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS14175 48d29747c1631aff3bc0838312c9f0cf 425 PANTHER PTHR24031 1 425 6.7E-188 T 22-04-2016 MED134_RS02280 20817486dfddd86d86aa54e50173d207 218 PANTHER PTHR12029:SF55 1 197 2.5E-44 T 22-04-2016 MED134_RS02280 20817486dfddd86d86aa54e50173d207 218 Gene3D G3DSA:3.40.1280.10 18 177 3.4E-46 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS02280 20817486dfddd86d86aa54e50173d207 218 PANTHER PTHR12029 1 197 2.5E-44 T 22-04-2016 MED134_RS02280 20817486dfddd86d86aa54e50173d207 218 Pfam PF00588 SpoU rRNA Methylase family 32 170 2.2E-34 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS02280 20817486dfddd86d86aa54e50173d207 218 SUPERFAMILY SSF75217 14 174 6.08E-40 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS11145 a868cfa11d837de0a58f6357d2e53871 217 SUPERFAMILY SSF88713 11 216 1.9E-50 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MED134_RS11145 a868cfa11d837de0a58f6357d2e53871 217 Gene3D G3DSA:3.20.20.370 16 216 1.6E-51 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 MED134_RS11145 a868cfa11d837de0a58f6357d2e53871 217 Pfam PF01522 Polysaccharide deacetylase 20 150 8.3E-24 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 MED134_RS11145 a868cfa11d837de0a58f6357d2e53871 217 PANTHER PTHR10587:SF70 12 213 3.2E-34 T 22-04-2016 MED134_RS11145 a868cfa11d837de0a58f6357d2e53871 217 PANTHER PTHR10587 12 213 3.2E-34 T 22-04-2016 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 Pfam PF02872 5'-nucleotidase, C-terminal domain 83 218 2.1E-22 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 SUPERFAMILY SSF55816 66 255 3.4E-44 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 Gene3D G3DSA:3.90.780.10 84 253 5.6E-36 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 PRINTS PR01607 Apyrase family signature 192 211 7.3E-10 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 PRINTS PR01607 Apyrase family signature 129 152 7.3E-10 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05230 86b06b90d464d8cc4b72e5635e4e3f87 257 PANTHER PTHR11575 32 251 8.8E-27 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS14810 40dc230c7283504246db2e32fd2d3cd8 271 SUPERFAMILY SSF53448 2 212 1.03E-47 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS14810 40dc230c7283504246db2e32fd2d3cd8 271 PANTHER PTHR22916 2 259 1.8E-40 T 22-04-2016 MED134_RS14810 40dc230c7283504246db2e32fd2d3cd8 271 Gene3D G3DSA:3.90.550.10 2 218 1.7E-43 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS14810 40dc230c7283504246db2e32fd2d3cd8 271 Pfam PF00535 Glycosyl transferase family 2 3 149 1.0E-24 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 Gene3D G3DSA:1.20.1250.20 252 439 3.9E-20 T 22-04-2016 MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 Gene3D G3DSA:1.20.1250.20 16 210 1.1E-20 T 22-04-2016 MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 SUPERFAMILY SSF103473 16 438 1.18E-48 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 Pfam PF07690 Major Facilitator Superfamily 28 393 2.5E-27 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 PANTHER PTHR19432 6 446 2.6E-55 T 22-04-2016 MED134_RS11245 ba1ba8054a885c16177d466c3776c4e1 450 PANTHER PTHR19432:SF35 6 446 2.6E-55 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00387 965 1075 9.4E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF00512 His Kinase A (phospho-acceptor) domain 852 916 4.0E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55785 317 424 1.92E-12 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.450.20 173 309 1.8E-12 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.40.50.2300 1094 1213 2.0E-32 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.565.10 920 1077 1.1E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF08447 PAS fold 330 417 2.8E-13 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF08447 PAS fold 738 825 1.3E-15 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PANTHER PTHR24423 306 513 1.5E-157 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PANTHER PTHR24423 789 1213 1.5E-157 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF00989 PAS fold 443 552 2.0E-17 T 22-04-2016 IPR013767 PAS fold GO:0006355 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:1.10.287.130 843 913 2.6E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF47384 836 917 4.12E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55785 563 694 1.64E-9 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1001 1015 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1035 1053 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1059 1072 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1019 1029 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00388 851 917 2.8E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF08448 PAS fold 582 698 5.9E-6 T 22-04-2016 IPR013656 PAS fold-4 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00086 514 555 67.0 T 22-04-2016 IPR001610 PAC motif MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00086 653 696 0.83 T 22-04-2016 IPR001610 PAC motif MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00086 381 423 0.11 T 22-04-2016 IPR001610 PAC motif MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00086 789 831 0.0028 T 22-04-2016 IPR001610 PAC motif MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 439 559 3.5E-19 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF52172 1095 1213 6.97E-33 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 965 1074 7.5E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Pfam PF00072 Response regulator receiver domain 1098 1208 3.6E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55785 429 553 9.42E-23 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55874 907 1073 1.31E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00448 1096 1208 7.1E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00091 574 639 0.19 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00091 715 783 68.0 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00091 442 508 6.0E-11 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00091 191 259 4.8 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SMART SM00091 66 128 190.0 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.450.20 310 421 1.4E-16 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.450.20 710 829 8.6E-19 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.450.20 565 694 2.9E-12 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55785 202 303 7.85E-10 T 22-04-2016 IPR000014 PAS domain MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 Gene3D G3DSA:3.30.450.20 429 553 7.8E-23 T 22-04-2016 MED134_RS14800 973b563b3f6d1e4f3ce959431df4000c 1216 SUPERFAMILY SSF55785 725 833 7.5E-17 T 22-04-2016 IPR000014 PAS domain MED134_RS00310 193b9f8ba3ef76111f80e8acacca4155 135 Pfam PF04940 Sensors of blue-light using FAD 1 91 7.6E-22 T 22-04-2016 IPR007024 BLUF domain GO:0009882|GO:0071949 MED134_RS00310 193b9f8ba3ef76111f80e8acacca4155 135 SUPERFAMILY SSF54975 1 110 6.87E-27 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MED134_RS00310 193b9f8ba3ef76111f80e8acacca4155 135 SMART SM01034 1 94 4.2E-18 T 22-04-2016 IPR007024 BLUF domain GO:0009882|GO:0071949 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 SUPERFAMILY SSF82866 572 770 3.01E-32 T 22-04-2016 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 Pfam PF03176 MMPL family 488 768 1.3E-15 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 Pfam PF03176 MMPL family 190 387 3.3E-15 T 22-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 PANTHER PTHR33406:SF2 1 767 5.7E-67 T 22-04-2016 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 SUPERFAMILY SSF82866 191 387 8.76E-32 T 22-04-2016 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 Gene3D G3DSA:1.20.1640.10 575 776 9.6E-31 T 22-04-2016 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 Gene3D G3DSA:1.20.1640.10 190 388 5.7E-35 T 22-04-2016 MED134_RS06835 7483b7fc68221e76d9ad83636d678517 805 PANTHER PTHR33406 1 767 5.7E-67 T 22-04-2016 MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 Pfam PF00005 ABC transporter 21 169 8.7E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 Gene3D G3DSA:3.40.50.300 1 220 2.7E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 PANTHER PTHR24220 3 227 8.1E-110 T 22-04-2016 MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 PANTHER PTHR24220:SF86 3 227 8.1E-110 T 22-04-2016 MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 SUPERFAMILY SSF52540 1 227 1.33E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11375 9e05b1200e601759f5b4ce47f3e961ca 233 SMART SM00382 30 217 4.8E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 SUPERFAMILY SSF53300 86 227 1.26E-33 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 SUPERFAMILY SSF53300 257 291 1.26E-33 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 Pfam PF07584 Aerotolerance regulator N-terminal 8 76 4.5E-7 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 SMART SM00327 89 287 7.4E-21 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 Pfam PF00092 von Willebrand factor type A domain 91 270 3.9E-23 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 PANTHER PTHR22550 10 332 3.1E-59 T 22-04-2016 MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 PANTHER PTHR22550:SF8 10 332 3.1E-59 T 22-04-2016 MED134_RS09940 33267c8ab0e44bf34ecfd0c10bfe0e59 344 Gene3D G3DSA:3.40.50.410 86 291 2.9E-28 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS03745 e3942ea52d0933671743c9df7e0b9b7c 236 Pfam PF13852 Protein of unknown function (DUF4197) 36 233 2.6E-78 T 22-04-2016 IPR025245 Protein of unknown function DUF4197 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 473 6.0E-155 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 237 251 5.1E-43 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 173 193 5.1E-43 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 205 219 5.1E-43 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 433 452 5.1E-43 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 271 298 5.1E-43 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 474 29.798 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 SMART SM00760 383 452 3.0E-30 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 SUPERFAMILY SSF48295 370 473 2.46E-31 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Gene3D G3DSA:3.40.50.300 130 303 6.7E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PANTHER PTHR30050:SF2 4 106 1.4E-175 T 22-04-2016 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PANTHER PTHR30050:SF2 137 474 1.4E-175 T 22-04-2016 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Pfam PF11638 DnaA N-terminal domain 6 68 4.0E-19 T 22-04-2016 IPR024633 DnaA N-terminal domain MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Gene3D G3DSA:1.10.8.60 307 374 7.2E-28 T 22-04-2016 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 384 452 3.4E-26 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PANTHER PTHR30050 4 106 1.4E-175 T 22-04-2016 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 PANTHER PTHR30050 137 474 1.4E-175 T 22-04-2016 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 ProSitePatterns PS01008 DnaA protein signature. 433 452 - T 22-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Pfam PF00308 Bacterial dnaA protein 139 357 5.5E-83 T 22-04-2016 IPR013317 Chromosomal replication initiator protein DnaA MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 SUPERFAMILY SSF52540 139 348 6.48E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 Gene3D G3DSA:1.10.1750.10 375 474 2.1E-34 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MED134_RS13715 4762167fcaaf6026ac9283796fe4e770 475 SMART SM00382 172 308 1.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 Gene3D G3DSA:2.170.130.10 29 154 6.9E-35 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552 462 564 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552 598 693 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552 8 427 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552:SF15 462 564 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552:SF15 598 693 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 PANTHER PTHR32552:SF15 8 427 7.8E-43 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 151 2.7E-22 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 SUPERFAMILY SSF56935 36 424 8.63E-103 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 SUPERFAMILY SSF56935 462 693 8.63E-103 T 22-04-2016 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 Gene3D G3DSA:2.40.170.20 155 693 4.3E-84 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS00560 464de2f4b442f10d5d64acfcc2ca65ee 693 Pfam PF00593 TonB dependent receptor 393 692 2.0E-23 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 SUPERFAMILY SSF55174 31 118 4.21E-11 T 22-04-2016 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 SUPERFAMILY SSF55120 91 338 1.52E-74 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 336 1.4E-91 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 Gene3D G3DSA:3.10.290.10 30 78 3.3E-13 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 150 164 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 PANTHER PTHR11079:SF73 7 347 2.8E-142 T 22-04-2016 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 Pfam PF00849 RNA pseudouridylate synthase 105 262 1.4E-36 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 SMART SM00363 31 91 5.0E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 Pfam PF01479 S4 domain 32 77 3.6E-8 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12995 2895a1dff8896cb62ca018e5768f9bac 347 PANTHER PTHR11079 7 347 2.8E-142 T 22-04-2016 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 Gene3D G3DSA:3.40.50.200 138 302 2.2E-41 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 Gene3D G3DSA:3.40.50.200 342 450 2.2E-41 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 PANTHER PTHR10795:SF419 142 303 2.0E-18 T 22-04-2016 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 PANTHER PTHR10795:SF419 359 435 2.0E-18 T 22-04-2016 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 Pfam PF00082 Subtilase family 185 431 1.1E-22 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 PANTHER PTHR10795 142 303 2.0E-18 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 PANTHER PTHR10795 359 435 2.0E-18 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 SUPERFAMILY SSF52743 139 306 1.28E-43 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS13510 55ceaceb41b9c0c4abf80a5e7c2b01b7 534 SUPERFAMILY SSF52743 349 451 1.28E-43 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS00645 064260a910c51830a6776a0cec3de6d8 119 PANTHER PTHR38590 5 117 2.9E-27 T 22-04-2016 MED134_RS00645 064260a910c51830a6776a0cec3de6d8 119 Pfam PF04480 Protein of unknown function (DUF559) 11 115 1.9E-30 T 22-04-2016 IPR007569 Domain of unknown function DUF559 MED134_RS00645 064260a910c51830a6776a0cec3de6d8 119 PANTHER PTHR38590:SF1 5 117 2.9E-27 T 22-04-2016 MED134_RS00645 064260a910c51830a6776a0cec3de6d8 119 SUPERFAMILY SSF52980 13 117 1.23E-11 T 22-04-2016 IPR011335 Restriction endonuclease type II-like MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 SUPERFAMILY SSF56935 381 458 2.61E-11 T 22-04-2016 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Pfam PF13598 Domain of unknown function (DUF4139) 221 664 2.3E-105 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 SUPERFAMILY SSF49464 314 371 4.71E-15 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 468 668 1.3E-40 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 32 298 1.5E-37 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Pfam PF13715 CarboxypepD_reg-like domain 315 391 3.8E-18 T 22-04-2016 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Pfam PF07715 TonB-dependent Receptor Plug Domain 401 463 1.2E-5 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 PANTHER PTHR31005 1 289 3.8E-55 T 22-04-2016 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 PANTHER PTHR31005 409 668 3.8E-55 T 22-04-2016 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 36 133 9.1E-18 T 22-04-2016 IPR025554 Domain of unknown function DUF4140 MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Gene3D G3DSA:2.60.40.1120 315 391 7.4E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS02720 7b26d66bdc88fe1d7e198e72f7fc00d4 670 Gene3D G3DSA:2.170.130.10 392 461 1.4E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 PANTHER PTHR30069 6 268 8.9E-90 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 PANTHER PTHR30069 286 1023 8.9E-90 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Pfam PF13620 Carboxypeptidase regulatory-like domain 28 110 5.0E-18 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Gene3D G3DSA:2.40.170.20 247 521 1.6E-33 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Gene3D G3DSA:2.40.170.20 571 912 1.6E-33 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Gene3D G3DSA:2.40.170.20 976 1022 1.6E-33 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 361 515 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 721 767 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 796 914 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 542 676 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 108 324 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF56935 978 1020 2.98E-49 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 SUPERFAMILY SSF49464 28 119 8.83E-15 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Gene3D G3DSA:2.170.130.10 117 246 6.5E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 Gene3D G3DSA:2.60.40.1120 29 116 7.4E-13 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 PANTHER PTHR30069:SF6 6 268 8.9E-90 T 22-04-2016 MED134_RS07720 e8f0c0926fa7a7d49f48f29182b77b2e 1091 PANTHER PTHR30069:SF6 286 1023 8.9E-90 T 22-04-2016 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 PANTHER PTHR11877:SF10 12 350 5.5E-64 T 22-04-2016 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 Gene3D G3DSA:3.40.47.10 1 197 3.3E-49 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 35 202 6.0E-20 T 22-04-2016 IPR001099 Chalcone/stilbene synthase, N-terminal MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 PANTHER PTHR11877 12 350 5.5E-64 T 22-04-2016 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 Gene3D G3DSA:3.40.47.10 198 350 1.1E-34 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 PIRSF PIRSF000451 1 350 9.7E-94 T 22-04-2016 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 220 349 8.1E-21 T 22-04-2016 IPR012328 Chalcone/stilbene synthase, C-terminal MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 SUPERFAMILY SSF53901 209 350 7.92E-36 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02635 b626112d9e2cae45a8d6d9711c5d29fe 350 SUPERFAMILY SSF53901 1 207 1.07E-47 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 Pfam PF03880 DbpA RNA binding domain 454 524 9.8E-17 T 22-04-2016 IPR005580 DbpA, RNA-binding domain MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 PANTHER PTHR24031:SF261 489 609 1.4E-194 T 22-04-2016 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 PANTHER PTHR24031:SF261 1 445 1.4E-194 T 22-04-2016 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 PANTHER PTHR24031 489 609 1.4E-194 T 22-04-2016 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 PANTHER PTHR24031 1 445 1.4E-194 T 22-04-2016 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 SMART SM00490 255 336 2.8E-33 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 Gene3D G3DSA:3.40.50.300 209 368 3.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 SMART SM00487 20 219 3.3E-60 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 SUPERFAMILY SSF52540 71 357 3.46E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 Pfam PF00270 DEAD/DEAH box helicase 26 192 1.3E-45 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 Pfam PF00271 Helicase conserved C-terminal domain 243 336 2.0E-27 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02270 bd11066bcd74b218f13164c30ae95669 638 Gene3D G3DSA:3.40.50.300 1 208 8.8E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13435 2bb33041245eddf1ca5a0abbfb5268dd 380 Pfam PF13439 Glycosyltransferase Family 4 19 180 8.5E-18 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS13435 2bb33041245eddf1ca5a0abbfb5268dd 380 Gene3D G3DSA:3.40.50.2000 195 355 4.4E-16 T 22-04-2016 MED134_RS13435 2bb33041245eddf1ca5a0abbfb5268dd 380 PANTHER PTHR12526 1 379 1.4E-43 T 22-04-2016 MED134_RS13435 2bb33041245eddf1ca5a0abbfb5268dd 380 SUPERFAMILY SSF53756 17 378 3.04E-61 T 22-04-2016 MED134_RS13435 2bb33041245eddf1ca5a0abbfb5268dd 380 Pfam PF00534 Glycosyl transferases group 1 193 355 1.1E-25 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS02310 a8487e0a2c8ac6a82c758f9a3156d3c6 127 SMART SM00257 75 124 4.3E-11 T 22-04-2016 IPR018392 LysM domain MED134_RS02310 a8487e0a2c8ac6a82c758f9a3156d3c6 127 Gene3D G3DSA:3.10.350.10 74 124 1.6E-11 T 22-04-2016 IPR018392 LysM domain MED134_RS02310 a8487e0a2c8ac6a82c758f9a3156d3c6 127 SUPERFAMILY SSF54106 74 124 2.09E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS02310 a8487e0a2c8ac6a82c758f9a3156d3c6 127 PANTHER PTHR34700 74 126 5.3E-13 T 22-04-2016 MED134_RS02310 a8487e0a2c8ac6a82c758f9a3156d3c6 127 Pfam PF01476 LysM domain 76 124 3.1E-9 T 22-04-2016 IPR018392 LysM domain MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 410 21.29 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 PANTHER PTHR22926 198 412 3.2E-131 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 PANTHER PTHR22926 2 154 3.2E-131 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 PANTHER PTHR22926:SF5 198 412 3.2E-131 T 22-04-2016 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 PANTHER PTHR22926:SF5 2 154 3.2E-131 T 22-04-2016 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 214 412 8.6E-72 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 ProSitePatterns PS01347 MraY family signature 1. 70 82 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 70 82 3.1E-5 T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 ProSitePatterns PS01348 MraY family signature 2. 235 246 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12515 f1c37fe9f308606353ffc063ac4be2e3 412 Pfam PF00953 Glycosyl transferase family 4 101 329 3.8E-39 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS14330 8132670facbaef5dcebab2d9c00813ed 151 PANTHER PTHR13947:SF7 49 133 1.8E-14 T 22-04-2016 MED134_RS14330 8132670facbaef5dcebab2d9c00813ed 151 SUPERFAMILY SSF55729 13 146 5.75E-23 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS14330 8132670facbaef5dcebab2d9c00813ed 151 PANTHER PTHR13947 49 133 1.8E-14 T 22-04-2016 MED134_RS14330 8132670facbaef5dcebab2d9c00813ed 151 Gene3D G3DSA:3.40.630.30 44 149 1.9E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS14330 8132670facbaef5dcebab2d9c00813ed 151 Pfam PF00583 Acetyltransferase (GNAT) family 52 128 1.8E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:4.10.860.10 623 661 1.7E-10 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Pfam PF00271 Helicase conserved C-terminal domain 430 543 2.0E-18 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:3.30.2060.10 159 230 2.3E-8 T 22-04-2016 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SUPERFAMILY SSF46600 619 659 1.03E-6 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:3.40.50.300 416 579 2.2E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 PANTHER PTHR24029 1 665 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 661 41.081 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SUPERFAMILY SSF52540 3 413 3.53E-120 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SMART SM00490 458 544 8.6E-19 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Pfam PF04851 Type III restriction enzyme, res subunit 10 137 2.9E-10 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:3.40.50.300 386 405 2.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:3.40.50.300 276 336 2.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Gene3D G3DSA:3.40.50.300 3 87 2.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Pfam PF02151 UvrB/uvrC motif 626 661 6.8E-8 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 2 656 9.6E-303 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SUPERFAMILY SSF52540 457 580 2.66E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SUPERFAMILY SSF52540 35 80 2.66E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 SMART SM00487 7 423 1.5E-27 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS03285 c5d33e52b508ae3cf0b8c9b7058f926b 666 Pfam PF12344 Ultra-violet resistance protein B 550 591 5.1E-18 T 22-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 Pfam PF09360 Iron-binding zinc finger CDGSH type 58 79 4.7E-8 T 22-04-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 Pfam PF09360 Iron-binding zinc finger CDGSH type 15 42 3.5E-10 T 22-04-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 SMART SM00704 10 47 5.3E-10 T 22-04-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 SMART SM00704 51 84 0.0024 T 22-04-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 PANTHER PTHR13680 2 79 5.3E-26 T 22-04-2016 MED134_RS14145 872e6cbb332b49124464b3ae75518fb6 84 PANTHER PTHR13680:SF22 2 79 5.3E-26 T 22-04-2016 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 SUPERFAMILY SSF46689 222 269 1.08E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 SMART SM00342 182 265 5.6E-13 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 Gene3D G3DSA:2.60.120.280 10 150 5.8E-4 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 Pfam PF12833 Helix-turn-helix domain 188 266 3.0E-15 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 PANTHER PTHR11019 14 273 3.5E-21 T 22-04-2016 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 Gene3D G3DSA:1.10.10.60 220 270 5.7E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 PANTHER PTHR11019:SF45 14 273 3.5E-21 T 22-04-2016 MED134_RS01500 ec61243bea6d954a771f28ef206d6359 275 SUPERFAMILY SSF51215 16 148 3.27E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 SUPERFAMILY SSF52402 1 147 7.37E-22 T 22-04-2016 MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 PANTHER PTHR31964 3 147 5.0E-12 T 22-04-2016 MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 SUPERFAMILY SSF52402 156 280 1.51E-12 T 22-04-2016 MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 Pfam PF00582 Universal stress protein family 3 139 1.0E-13 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 Gene3D G3DSA:3.40.50.620 2 147 1.7E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04625 972163a3905fb15d5559e1f0ce58d410 282 Gene3D G3DSA:3.40.50.620 156 280 2.8E-8 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 SUPERFAMILY SSF52540 598 776 2.55E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 577 783 2.9E-43 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 PANTHER PTHR32309 23 121 8.2E-116 T 22-04-2016 MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 PANTHER PTHR32309 204 795 8.2E-116 T 22-04-2016 MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 Gene3D G3DSA:3.40.50.300 599 775 1.4E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 Pfam PF13614 AAA domain 599 720 5.7E-9 T 22-04-2016 IPR025669 AAA domain MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 PANTHER PTHR32309:SF13 23 121 8.2E-116 T 22-04-2016 MED134_RS13345 04d09c057cb8dae6e60f87b916f1d66f 812 PANTHER PTHR32309:SF13 204 795 8.2E-116 T 22-04-2016 MED134_RS12815 91ed03f63c5d68eaa8315a908f97efad 373 Pfam PF00144 Beta-lactamase 86 311 4.5E-17 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS12815 91ed03f63c5d68eaa8315a908f97efad 373 Gene3D G3DSA:3.40.710.10 76 313 4.2E-29 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS12815 91ed03f63c5d68eaa8315a908f97efad 373 PANTHER PTHR22935 86 296 4.6E-16 T 22-04-2016 MED134_RS12815 91ed03f63c5d68eaa8315a908f97efad 373 SUPERFAMILY SSF56601 29 370 3.94E-55 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 Pfam PF01553 Acyltransferase 71 200 2.2E-7 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 SUPERFAMILY SSF69593 56 252 1.83E-10 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 PANTHER PTHR37323 313 603 8.6E-71 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 PANTHER PTHR37323 1 293 8.6E-71 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 PANTHER PTHR37323:SF1 313 603 8.6E-71 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 PANTHER PTHR37323:SF1 1 293 8.6E-71 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 Pfam PF13444 Acetyltransferase (GNAT) domain 343 444 1.8E-21 T 22-04-2016 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 SMART SM00563 81 203 2.6E-5 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS08200 95a12c0acb7f25a9cb4bd8f31262ef06 604 SUPERFAMILY SSF55729 328 514 1.91E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS10285 8acff768a31abd468c0f9e0be466a054 385 PANTHER PTHR30477 4 307 4.5E-97 T 22-04-2016 MED134_RS10285 8acff768a31abd468c0f9e0be466a054 385 PANTHER PTHR30477:SF8 4 307 4.5E-97 T 22-04-2016 MED134_RS10285 8acff768a31abd468c0f9e0be466a054 385 Gene3D G3DSA:1.10.3470.10 43 276 3.2E-7 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS10285 8acff768a31abd468c0f9e0be466a054 385 SUPERFAMILY SSF81345 9 271 1.96E-25 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS10285 8acff768a31abd468c0f9e0be466a054 385 Pfam PF00950 ABC 3 transport family 9 274 6.8E-50 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 131 189 7.7E-11 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 PANTHER PTHR12725 1 205 5.0E-23 T 22-04-2016 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 PANTHER PTHR12725:SF63 1 205 5.0E-23 T 22-04-2016 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 62 184 2.0E-6 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 Gene3D G3DSA:3.40.50.1000 5 198 2.1E-33 T 22-04-2016 IPR023214 HAD-like domain MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 3.0E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 3.0E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 47 186 1.0E-12 T 22-04-2016 IPR023214 HAD-like domain MED134_RS02955 215ee12daff3d7320f45c0edc0f1137e 210 SUPERFAMILY SSF56784 8 196 3.12E-34 T 22-04-2016 IPR023214 HAD-like domain MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PANTHER PTHR22594 6 176 1.0E-214 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PANTHER PTHR22594 195 479 1.0E-214 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 SUPERFAMILY SSF55681 114 475 5.6E-92 T 22-04-2016 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 SUPERFAMILY SSF50249 3 97 1.44E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 473 1.2E-84 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PRINTS PR01042 Aspartyl-tRNA synthetase signature 220 233 3.3E-12 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PRINTS PR01042 Aspartyl-tRNA synthetase signature 395 411 3.3E-12 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PRINTS PR01042 Aspartyl-tRNA synthetase signature 435 449 3.3E-12 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 216 3.3E-12 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PANTHER PTHR22594:SF6 6 176 1.0E-214 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 PANTHER PTHR22594:SF6 195 479 1.0E-214 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 Pfam PF01336 OB-fold nucleic acid binding domain 20 93 2.1E-10 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 480 42.406 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 8 480 8.8E-173 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 Gene3D G3DSA:2.40.50.140 4 98 4.6E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS06845 92d0a51556e21d01075a58f610e819b4 480 Gene3D G3DSA:3.30.930.10 108 477 9.9E-109 T 22-04-2016 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 Pfam PF01433 Peptidase family M1 37 335 8.1E-49 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 SUPERFAMILY SSF55486 210 437 1.9E-51 T 22-04-2016 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 Gene3D G3DSA:1.25.10.10 472 584 1.2E-4 T 22-04-2016 IPR011989 Armadillo-like helical MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 Gene3D G3DSA:1.25.10.10 621 670 1.2E-4 T 22-04-2016 IPR011989 Armadillo-like helical MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 Gene3D G3DSA:1.10.390.10 306 438 3.4E-20 T 22-04-2016 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 SUPERFAMILY SSF48371 612 676 8.06E-6 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 SUPERFAMILY SSF48371 492 574 8.06E-6 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 PANTHER PTHR11533 38 435 3.9E-63 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 PANTHER PTHR11533:SF163 38 435 3.9E-63 T 22-04-2016 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 SUPERFAMILY SSF63737 27 200 2.48E-23 T 22-04-2016 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 183 198 3.6E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 3.6E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS03060 28b86a264f1fc020aa9c321579c9e81c 698 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 3.6E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Pfam PF13620 Carboxypeptidase regulatory-like domain 438 518 2.2E-9 T 22-04-2016 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 SUPERFAMILY SSF48452 27 161 1.17E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Gene3D G3DSA:2.130.10.10 221 383 3.6E-12 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 SUPERFAMILY SSF82171 198 376 1.44E-14 T 22-04-2016 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 SUPERFAMILY SSF49478 438 504 9.81E-8 T 22-04-2016 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 PANTHER PTHR30128 513 650 1.1E-33 T 22-04-2016 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Pfam PF07676 WD40-like Beta Propeller Repeat 333 371 0.0027 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Pfam PF07676 WD40-like Beta Propeller Repeat 220 243 5.3E-5 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Pfam PF07676 WD40-like Beta Propeller Repeat 286 318 7.2E-6 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Gene3D G3DSA:3.30.1330.60 537 649 2.0E-33 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 SUPERFAMILY SSF103088 527 647 3.79E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Gene3D G3DSA:1.25.40.10 26 128 5.8E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 PRINTS PR01021 OMPA domain signature 587 603 8.46E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 PRINTS PR01021 OMPA domain signature 572 587 8.46E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 PRINTS PR01021 OMPA domain signature 542 564 8.46E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Pfam PF00691 OmpA family 541 630 3.2E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS12560 f5ed39f4ea08336d0d9ae6058ea38058 650 Gene3D G3DSA:2.60.40.1120 438 518 3.9E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS05790 38a665e3d09f0c2c585bdf7e080640b1 371 Gene3D G3DSA:3.90.550.10 44 255 5.4E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS05790 38a665e3d09f0c2c585bdf7e080640b1 371 PANTHER PTHR22916 39 232 6.7E-22 T 22-04-2016 MED134_RS05790 38a665e3d09f0c2c585bdf7e080640b1 371 PANTHER PTHR22916:SF23 39 232 6.7E-22 T 22-04-2016 MED134_RS05790 38a665e3d09f0c2c585bdf7e080640b1 371 Pfam PF00535 Glycosyl transferase family 2 46 180 5.5E-21 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS05790 38a665e3d09f0c2c585bdf7e080640b1 371 SUPERFAMILY SSF53448 38 298 1.04E-36 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS12390 9aa86c103318893b5a44c072ac81eaf5 165 SUPERFAMILY SSF55136 6 165 1.24E-23 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS12390 9aa86c103318893b5a44c072ac81eaf5 165 Pfam PF06445 GyrI-like small molecule binding domain 9 165 2.7E-24 T 22-04-2016 IPR029442 GyrI-like small molecule binding domain MED134_RS12390 9aa86c103318893b5a44c072ac81eaf5 165 Gene3D G3DSA:3.20.80.10 5 165 6.2E-29 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS12390 9aa86c103318893b5a44c072ac81eaf5 165 SMART SM00871 7 165 9.5E-25 T 22-04-2016 IPR010499 Bacterial transcription activator, effector binding MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 Gene3D G3DSA:3.30.420.10 8 175 3.4E-37 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 SUPERFAMILY SSF53098 6 177 3.29E-49 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 Pfam PF00929 Exonuclease 11 165 2.2E-20 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 PANTHER PTHR30231:SF9 1 256 3.8E-122 T 22-04-2016 MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 PANTHER PTHR30231 1 256 3.8E-122 T 22-04-2016 MED134_RS05095 d74298a78e6719ab6093827c58723f44 257 SMART SM00479 8 174 4.8E-30 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF04983 RNA polymerase Rpb1, domain 3 506 660 1.0E-24 T 22-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF00623 RNA polymerase Rpb1, domain 2 411 502 7.3E-26 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF00623 RNA polymerase Rpb1, domain 2 361 415 9.5E-9 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376 1181 1264 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376 1346 1406 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376 986 1160 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376 1 954 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 16 1294 0.0 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 SUPERFAMILY SSF64484 1136 1295 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 SUPERFAMILY SSF64484 12 955 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 SUPERFAMILY SSF64484 1337 1409 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Gene3D G3DSA:2.40.50.100 1159 1213 3.0E-8 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Gene3D G3DSA:2.40.50.100 1078 1124 3.2E-4 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF05000 RNA polymerase Rpb1, domain 4 689 774 2.4E-15 T 22-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1419 10.171 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF04997 RNA polymerase Rpb1, domain 1 12 359 5.2E-82 T 22-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 SMART SM00663 252 531 1.3E-170 T 22-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376:SF32 1181 1264 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376:SF32 1346 1406 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376:SF32 986 1160 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 PANTHER PTHR19376:SF32 1 954 0.0 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Pfam PF04998 RNA polymerase Rpb1, domain 5 777 1296 2.2E-67 T 22-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Gene3D G3DSA:2.40.40.20 434 505 2.3E-35 T 22-04-2016 MED134_RS04880 407aba3b839f46045f465e2fbb124ec2 1433 Gene3D G3DSA:2.40.40.20 366 393 2.3E-35 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00458 Haem peroxidase superfamily signature 323 338 1.2E-19 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00458 Haem peroxidase superfamily signature 159 176 1.2E-19 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00458 Haem peroxidase superfamily signature 99 113 1.2E-19 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00458 Haem peroxidase superfamily signature 177 189 1.2E-19 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00458 Haem peroxidase superfamily signature 263 278 1.2E-19 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Hamap MF_01961 Catalase-peroxidase [katG]. 13 738 40.06 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.420.10 590 711 4.9E-42 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 SUPERFAMILY SSF48113 31 436 3.54E-145 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 SUPERFAMILY SSF48113 437 737 3.98E-100 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PANTHER PTHR30555:SF0 1 738 0.0 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 263 273 - T 22-04-2016 IPR019793 Peroxidases heam-ligand binding site MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PANTHER PTHR30555 1 738 0.0 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Pfam PF00141 Peroxidase 410 711 6.2E-35 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Pfam PF00141 Peroxidase 89 403 8.6E-50 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.420.10 256 278 4.2E-49 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.420.10 315 414 4.2E-49 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 ProSitePatterns PS00436 Peroxidases active site signature. 99 110 - T 22-04-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 23 737 0.0 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.520.10 716 738 1.4E-55 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.520.10 243 255 5.5E-72 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.520.10 439 589 1.4E-55 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 Gene3D G3DSA:1.10.520.10 56 210 5.5E-72 T 22-04-2016 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 35 57 1.0E-44 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 271 294 1.0E-44 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 61 74 1.0E-44 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 76 101 1.0E-44 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS08125 ce29ba397a7428c0203c069b59f9fade 738 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 487 513 1.0E-44 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 MED134_RS13740 881c512c0b6f4c56109cd12a45d8d675 196 SUPERFAMILY SSF55729 3 176 1.85E-33 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS13740 881c512c0b6f4c56109cd12a45d8d675 196 Pfam PF13302 Acetyltransferase (GNAT) domain 13 149 7.4E-15 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS13740 881c512c0b6f4c56109cd12a45d8d675 196 PANTHER PTHR13256:SF20 5 184 2.0E-56 T 22-04-2016 MED134_RS13740 881c512c0b6f4c56109cd12a45d8d675 196 PANTHER PTHR13256 5 184 2.0E-56 T 22-04-2016 MED134_RS13740 881c512c0b6f4c56109cd12a45d8d675 196 Gene3D G3DSA:3.40.630.30 2 184 3.1E-48 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.447 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 SUPERFAMILY SSF54211 87 165 5.56E-27 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 SUPERFAMILY SSF54768 16 83 3.56E-22 T 22-04-2016 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 3.2E-31 T 22-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 Gene3D G3DSA:3.30.160.20 17 80 4.4E-28 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 169 8.7E-63 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 PANTHER PTHR13718 17 167 4.8E-64 T 22-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 82 1.2E-27 T 22-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 22-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site MED134_RS12320 18937fed5b2cd7ed006eb8d5020b6d45 174 Gene3D G3DSA:3.30.230.10 83 165 1.0E-33 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 Pfam PF01545 Cation efflux family 88 262 3.1E-16 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 Gene3D G3DSA:3.30.70.100 3 58 2.4E-5 T 22-04-2016 MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 Gene3D G3DSA:1.20.1510.10 84 262 5.1E-22 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 PANTHER PTHR11562:SF17 7 261 5.9E-19 T 22-04-2016 MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 SUPERFAMILY SSF161111 84 261 5.62E-28 T 22-04-2016 MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 SUPERFAMILY SSF55008 1 61 1.31E-9 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS01720 92194ebd1e1434acca284392eaa5d560 264 PANTHER PTHR11562 7 261 5.9E-19 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 2.6E-24 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PRINTS PR01703 Manganese superoxide dismutase signature 68 81 2.6E-24 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.6E-24 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PRINTS PR01703 Manganese superoxide dismutase signature 121 129 2.6E-24 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.6E-24 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 22-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PIRSF PIRSF000349 1 202 1.1E-79 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 PANTHER PTHR11404 1 200 4.2E-104 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 SUPERFAMILY SSF54719 87 200 1.17E-44 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 85 8.0E-31 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 SUPERFAMILY SSF46609 1 86 3.4E-33 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 Gene3D G3DSA:1.10.287.990 20 85 2.7E-26 T 22-04-2016 MED134_RS08980 4be04b58c30c37f3c842697b393ab399 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 92 195 9.2E-40 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 425 2.9E-182 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 SMART SM00962 99 295 4.0E-111 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 SMART SM00963 1 86 1.6E-30 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 PANTHER PTHR11564:SF7 1 430 4.1E-248 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Gene3D G3DSA:1.20.120.140 2 89 6.0E-31 T 22-04-2016 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 SUPERFAMILY SSF52540 42 353 4.51E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Gene3D G3DSA:1.10.260.30 326 427 4.2E-40 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 PANTHER PTHR11564 1 430 4.1E-248 T 22-04-2016 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Pfam PF00448 SRP54-type protein, GTPase domain 99 295 1.3E-72 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 SMART SM00382 98 300 9.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 438 33.087 T 22-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.5E-20 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Pfam PF02978 Signal peptide binding domain 326 423 6.9E-35 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 Gene3D G3DSA:3.40.50.300 97 296 5.7E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03450 e3813d97f41a6e90331adac9e378183d 442 SUPERFAMILY SSF47446 326 426 5.07E-37 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 MED134_RS02435 01531c9747c64870881771f77e861f14 378 Gene3D G3DSA:3.40.50.1000 1 152 6.2E-31 T 22-04-2016 IPR023214 HAD-like domain MED134_RS02435 01531c9747c64870881771f77e861f14 378 Gene3D G3DSA:3.30.230.40 188 275 9.6E-37 T 22-04-2016 MED134_RS02435 01531c9747c64870881771f77e861f14 378 SUPERFAMILY SSF56784 2 149 6.15E-29 T 22-04-2016 IPR023214 HAD-like domain MED134_RS02435 01531c9747c64870881771f77e861f14 378 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 144 1.5E-29 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MED134_RS02435 01531c9747c64870881771f77e861f14 378 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 188 378 36.12 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 SUPERFAMILY SSF54211 188 271 5.06E-31 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS02435 01531c9747c64870881771f77e861f14 378 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 340 352 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 SUPERFAMILY SSF54211 274 362 3.41E-29 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS02435 01531c9747c64870881771f77e861f14 378 Gene3D G3DSA:3.30.230.40 279 378 4.2E-28 T 22-04-2016 MED134_RS02435 01531c9747c64870881771f77e861f14 378 PANTHER PTHR23133:SF2 10 97 1.7E-130 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 PANTHER PTHR23133:SF2 184 378 1.7E-130 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 PANTHER PTHR23133 10 97 1.7E-130 T 22-04-2016 MED134_RS02435 01531c9747c64870881771f77e861f14 378 PANTHER PTHR23133 184 378 1.7E-130 T 22-04-2016 MED134_RS02435 01531c9747c64870881771f77e861f14 378 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 247 260 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 217 358 1.0E-59 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 150 2.3E-48 T 22-04-2016 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15|UniPathway: UPA00031|UniPathway: UPA00031 MED134_RS02435 01531c9747c64870881771f77e861f14 378 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 147 4.8E-18 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 Pfam PF01036 Bacteriorhodopsin-like protein 22 239 6.0E-31 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 SMART SM01021 19 247 2.7E-27 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 Gene3D G3DSA:1.20.1070.10 13 242 4.4E-87 T 22-04-2016 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 PIRSF PIRSF038142 4 245 1.2E-79 T 22-04-2016 IPR017402 Proteorhodopsin GO:0006811|GO:0010461|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 SUPERFAMILY SSF81321 17 239 2.29E-61 T 22-04-2016 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 PRINTS PR00251 Bacterial opsin signature 18 38 2.9E-5 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 PRINTS PR00251 Bacterial opsin signature 137 158 2.9E-5 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 PRINTS PR00251 Bacterial opsin signature 213 231 2.9E-5 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS00280 3c9d0c27b13b4697d4d13ffb1fdd38c8 247 PRINTS PR00251 Bacterial opsin signature 179 197 2.9E-5 T 22-04-2016 IPR001425 Archaeal/bacterial/fungal rhodopsins GO:0005216|GO:0006811|GO:0016020 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 135 16.114 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 Pfam PF02130 Uncharacterized protein family UPF0054 21 132 1.0E-26 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 SUPERFAMILY SSF55486 7 134 7.32E-36 T 22-04-2016 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 PANTHER PTHR22881 35 133 3.7E-14 T 22-04-2016 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 35 133 3.3E-30 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MED134_RS09170 4ad803c303ed447ddb407dc2e216203c 135 Gene3D G3DSA:3.40.390.30 5 133 8.4E-33 T 22-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 MED134_RS03970 871c1d7b0c5a9b449f17603dc75d7a37 184 Pfam PF00578 AhpC/TSA family 12 136 5.7E-15 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS03970 871c1d7b0c5a9b449f17603dc75d7a37 184 SUPERFAMILY SSF52833 5 184 1.57E-48 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS03970 871c1d7b0c5a9b449f17603dc75d7a37 184 PANTHER PTHR10681:SF91 4 184 8.2E-65 T 22-04-2016 MED134_RS03970 871c1d7b0c5a9b449f17603dc75d7a37 184 PANTHER PTHR10681 4 184 8.2E-65 T 22-04-2016 MED134_RS03970 871c1d7b0c5a9b449f17603dc75d7a37 184 Gene3D G3DSA:3.40.30.10 11 174 7.0E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS12130 225ded5cac4a3ed03f29018d9cb6cda3 203 PANTHER PTHR33508 1 203 1.3E-46 T 22-04-2016 MED134_RS12130 225ded5cac4a3ed03f29018d9cb6cda3 203 Pfam PF01914 MarC family integral membrane protein 2 199 6.7E-47 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS12130 225ded5cac4a3ed03f29018d9cb6cda3 203 PANTHER PTHR33508:SF1 1 203 1.3E-46 T 22-04-2016 MED134_RS12130 225ded5cac4a3ed03f29018d9cb6cda3 203 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 196 2.7E-41 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 PANTHER PTHR19136 5 265 2.9E-73 T 22-04-2016 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 124 152 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 SUPERFAMILY SSF51161 4 248 8.04E-63 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 Gene3D G3DSA:2.160.10.10 90 249 3.3E-52 T 22-04-2016 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 PANTHER PTHR19136:SF52 5 265 2.9E-73 T 22-04-2016 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 199 1.8E-10 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 Gene3D G3DSA:1.10.166.10 1 66 1.1E-25 T 22-04-2016 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 123 156 0.0026 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS04330 7d2b7023f9ec1b288c861c50a9a86e7c 271 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 65 2.5E-22 T 22-04-2016 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 Gene3D G3DSA:3.40.50.150 209 401 6.9E-52 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 SUPERFAMILY SSF53335 119 401 7.37E-67 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 Pfam PF01189 16S rRNA methyltransferase RsmB/F 218 399 2.2E-43 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PANTHER PTHR22807 119 401 7.5E-97 T 22-04-2016 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PANTHER PTHR22807:SF33 119 401 7.5E-97 T 22-04-2016 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 Gene3D G3DSA:3.30.70.1170 152 207 1.3E-9 T 22-04-2016 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 384 401 4.7E-28 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 345 361 4.7E-28 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 199 213 4.7E-28 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 238 4.7E-28 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01885 ec0a23987ce003a4bcd32593cbd0ff45 402 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 295 307 4.7E-28 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 Pfam PF00005 ABC transporter 19 164 4.5E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 3 239 5.1E-112 T 22-04-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 SMART SM00382 27 214 6.1E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 Gene3D G3DSA:3.40.50.300 3 232 1.4E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 PANTHER PTHR24220 4 236 7.7E-140 T 22-04-2016 MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 SUPERFAMILY SSF52540 3 235 1.42E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05010 81a03f3e5dc3fbd6d9b68c194a530ee4 245 PANTHER PTHR24220:SF497 4 236 7.7E-140 T 22-04-2016 MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 SUPERFAMILY SSF51735 7 256 4.64E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PANTHER PTHR24319:SF23 1 259 8.0E-57 T 22-04-2016 MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 255 6.7E-44 T 22-04-2016 MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 Gene3D G3DSA:3.40.50.720 2 256 2.6E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.0E-27 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS12715 10c1041eb5ea879d73c04b2d0e87c178 259 PANTHER PTHR24319 1 259 8.0E-57 T 22-04-2016 MED134_RS01845 21e235d1bb3f4bb01d035a84b05f6fc4 118 PANTHER PTHR37466 1 118 6.3E-41 T 22-04-2016 MED134_RS01845 21e235d1bb3f4bb01d035a84b05f6fc4 118 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 4 117 6.1E-50 T 22-04-2016 IPR018714 Protein of unknown function DUF2237 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 Gene3D G3DSA:3.80.30.20 137 368 2.6E-71 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 PANTHER PTHR11918:SF57 9 438 1.9E-169 T 22-04-2016 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 Gene3D G3DSA:2.40.50.140 371 433 2.5E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 10 430 3.0E-119 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 Pfam PF04055 Radical SAM superfamily 144 314 8.8E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 PANTHER PTHR11918 9 438 1.9E-169 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 SUPERFAMILY SSF102114 101 364 3.79E-55 T 22-04-2016 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 9 432 61.617 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 Pfam PF00919 Uncharacterized protein family UPF0004 10 108 2.8E-25 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 10 429 8.6E-149 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MED134_RS12820 605306fa5379ab283c8888cb613c2a09 450 SMART SM00729 138 356 1.0E-43 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 PANTHER PTHR14226 27 450 8.9E-76 T 22-04-2016 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 SUPERFAMILY SSF52151 125 311 3.92E-54 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 SUPERFAMILY SSF52151 26 97 3.92E-54 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 Pfam PF01734 Patatin-like phospholipase 30 218 4.2E-27 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 PANTHER PTHR14226:SF37 27 450 8.9E-76 T 22-04-2016 MED134_RS08920 e272b2f59b5ab7819c29bb83ac6380b3 743 Gene3D G3DSA:3.40.1090.10 30 217 2.0E-14 T 22-04-2016 MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 44 497 5.2E-7 T 22-04-2016 IPR001087 GDSL lipase/esterase GO:0016788 MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 SUPERFAMILY SSF52266 43 86 9.66E-10 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 Gene3D G3DSA:3.40.50.1110 136 207 2.1E-12 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 Gene3D G3DSA:3.40.50.1110 45 81 2.1E-12 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 Gene3D G3DSA:3.40.50.1110 392 505 2.1E-12 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 SUPERFAMILY SSF52266 416 502 6.33E-10 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 SUPERFAMILY SSF52266 180 306 9.66E-10 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS07490 d7c222b9357baec99d89476f705f43eb 527 SUPERFAMILY SSF52266 142 152 9.66E-10 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS09805 098b1011390cda649a1453234f3be326 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 120 133 - T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 200 445 9.4E-90 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PIRSF PIRSF000185 20 447 2.2E-119 T 22-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 SUPERFAMILY SSF53223 5 194 1.82E-75 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 233 253 3.3E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 191 213 3.3E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 3.3E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 112 126 3.3E-31 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Gene3D G3DSA:3.40.50.720 207 371 1.2E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09805 098b1011390cda649a1453234f3be326 447 SMART SM00839 202 445 9.3E-95 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Gene3D G3DSA:1.10.285.10 5 65 1.1E-24 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Gene3D G3DSA:1.10.285.10 372 447 8.6E-29 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Gene3D G3DSA:3.40.192.10 66 187 5.6E-64 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 55 183 3.3E-52 T 22-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PANTHER PTHR11606 1 447 9.3E-260 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 PANTHER PTHR11606:SF4 1 447 9.3E-260 T 22-04-2016 MED134_RS09805 098b1011390cda649a1453234f3be326 447 SUPERFAMILY SSF51735 200 446 9.85E-80 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 Pfam PF00696 Amino acid kinase family 7 243 1.2E-33 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 Gene3D G3DSA:3.40.1160.10 5 244 2.4E-64 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 PIRSF PIRSF000728 1 258 1.6E-65 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 TIGRFAM TIGR00761 argB: acetylglutamate kinase 8 242 1.8E-52 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 SUPERFAMILY SSF53633 5 249 1.54E-47 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS11765 3dc2f91a0406cf2f883f346758d3a1d1 261 PANTHER PTHR23342 4 238 2.9E-58 T 22-04-2016 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 PANTHER PTHR21180 135 401 3.0E-118 T 22-04-2016 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 SUPERFAMILY SSF102114 46 286 4.58E-19 T 22-04-2016 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 PANTHER PTHR21180:SF9 135 401 3.0E-118 T 22-04-2016 IPR023874 DNA modification/repair radical SAM protein, putative MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 Gene3D G3DSA:3.20.20.70 46 242 3.1E-15 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 Pfam PF04055 Radical SAM superfamily 63 238 5.8E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 SUPERFAMILY SSF47781 303 382 3.89E-11 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 6 418 3.2E-200 T 22-04-2016 IPR023874 DNA modification/repair radical SAM protein, putative MED134_RS11060 b37377795b0044e4b6596cec00eba592 428 Gene3D G3DSA:1.10.150.320 326 360 8.8E-5 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 Hamap MF_00577 Urocanate hydratase [hutU]. 55 651 45.096 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 Pfam PF01175 Urocanase 84 637 8.4E-245 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 PIRSF PIRSF001423 65 656 9.1E-189 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 PANTHER PTHR12216:SF3 2 659 0.0 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 ProSitePatterns PS01233 Urocanase signature. 532 547 - T 22-04-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 Gene3D G3DSA:3.40.1770.10 79 214 1.5E-61 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 Gene3D G3DSA:3.40.1770.10 278 383 8.0E-103 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 Gene3D G3DSA:3.40.1770.10 420 645 8.0E-103 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 PANTHER PTHR12216 2 659 0.0 T 22-04-2016 MED134_RS11580 6e6d7e6dc66a2181d52ac92a8897a816 661 SUPERFAMILY SSF111326 84 645 1.57E-221 T 22-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 327 1.1E-92 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 SUPERFAMILY SSF52418 71 326 5.89E-78 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 328 29.98 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 PANTHER PTHR11922 73 330 2.0E-77 T 22-04-2016 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 PANTHER PTHR11922:SF5 73 330 2.0E-77 T 22-04-2016 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 Pfam PF00591 Glycosyl transferase family, a/b domain 72 318 8.9E-68 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 62 6.7E-12 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 SUPERFAMILY SSF47648 1 67 2.62E-12 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 Gene3D G3DSA:1.20.970.10 1 63 9.8E-15 T 22-04-2016 MED134_RS13040 c8bc0185ba7212f95ba5584ad37e0722 330 Gene3D G3DSA:3.40.1030.10 71 330 1.6E-81 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 Gene3D G3DSA:3.40.1370.10 58 207 7.1E-53 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 SUPERFAMILY SSF52166 1 206 2.88E-68 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 1.9E-58 T 22-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 6.3E-70 T 22-04-2016 IPR013005 50S ribosomal protein uL4 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 208 30.559 T 22-04-2016 IPR013005 50S ribosomal protein uL4 MED134_RS12240 6f04417bfcbeb89f2d85da41979f07e7 209 PANTHER PTHR10746 1 207 1.4E-72 T 22-04-2016 IPR013005 50S ribosomal protein uL4 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 Gene3D G3DSA:3.30.70.360 213 330 8.5E-34 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 PANTHER PTHR11014:SF63 17 422 1.3E-132 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 PANTHER PTHR11014 17 422 1.3E-132 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 34 408 2.8E-103 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 PIRSF PIRSF005962 17 422 2.8E-121 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 Pfam PF01546 Peptidase family M20/M25/M40 91 416 4.7E-31 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 SUPERFAMILY SSF53187 331 420 6.56E-80 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 SUPERFAMILY SSF53187 21 229 6.56E-80 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 Pfam PF07687 Peptidase dimerisation domain 217 316 2.3E-10 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 Gene3D G3DSA:3.40.630.10 16 210 5.2E-97 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 Gene3D G3DSA:3.40.630.10 331 420 5.2E-97 T 22-04-2016 MED134_RS02120 515ef19405d85dd2899f9cf8ae37d591 422 SUPERFAMILY SSF55031 216 329 6.93E-27 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS01250 25f8c3db13c6bd831ad64c83eded42c6 79 PANTHER PTHR37805 1 75 1.4E-27 T 22-04-2016 MED134_RS01250 25f8c3db13c6bd831ad64c83eded42c6 79 Pfam PF07308 Protein of unknown function (DUF1456) 5 72 5.3E-30 T 22-04-2016 IPR009921 Domain of unknown function DUF1456 MED134_RS01250 25f8c3db13c6bd831ad64c83eded42c6 79 PANTHER PTHR37805:SF1 1 75 1.4E-27 T 22-04-2016 MED134_RS00955 18039d048d67d56a7a4cd1ec46111e76 205 PIRSF PIRSF006324 1 204 1.1E-48 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS00955 18039d048d67d56a7a4cd1ec46111e76 205 PANTHER PTHR30086 2 202 5.0E-54 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS00955 18039d048d67d56a7a4cd1ec46111e76 205 PANTHER PTHR30086:SF3 2 202 5.0E-54 T 22-04-2016 MED134_RS00955 18039d048d67d56a7a4cd1ec46111e76 205 Pfam PF01810 LysE type translocator 14 203 1.2E-33 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 SUPERFAMILY SSF52540 97 395 1.16E-87 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 380 389 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 SUPERFAMILY SSF50615 11 95 8.11E-27 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Gene3D G3DSA:3.40.50.300 96 396 7.4E-108 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 524 4.4E-228 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 5.5E-17 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 396 519 6.8E-42 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 151 389 1.2E-69 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 PANTHER PTHR15184 334 509 9.1E-273 T 22-04-2016 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 PANTHER PTHR15184 1 315 9.1E-273 T 22-04-2016 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 PANTHER PTHR15184:SF3 334 509 9.1E-273 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 PANTHER PTHR15184:SF3 1 315 9.1E-273 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Gene3D G3DSA:2.40.30.20 3 94 5.7E-37 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 525 47.566 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 SUPERFAMILY SSF47917 397 523 3.66E-37 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS09420 e2318d7ef712695e3144efe376e81c7d 525 Gene3D G3DSA:1.20.150.20 397 523 3.1E-43 T 22-04-2016 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 SUPERFAMILY SSF53623 88 290 3.4E-42 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 PANTHER PTHR23135 1 423 2.1E-119 T 22-04-2016 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 SUPERFAMILY SSF63418 13 86 7.06E-19 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 18 422 1.9E-112 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 SUPERFAMILY SSF53244 294 422 3.66E-28 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Pfam PF08245 Mur ligase middle domain 94 272 1.4E-40 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Gene3D G3DSA:3.90.190.20 292 422 1.0E-33 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Pfam PF01225 Mur ligase family, catalytic domain 15 83 1.1E-6 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Gene3D G3DSA:3.40.1190.10 71 290 1.6E-55 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 PANTHER PTHR23135:SF3 1 423 2.1E-119 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Gene3D G3DSA:3.40.1390.10 13 60 7.4E-15 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 1 423 29.787 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS11870 b12d4e6c9d9cdd8b774cf7a2a6bb36a1 424 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 374 6.9E-9 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 Gene3D G3DSA:3.40.47.10 165 327 6.3E-48 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 PANTHER PTHR34069 2 332 2.0E-126 T 22-04-2016 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 Gene3D G3DSA:3.40.47.10 3 164 3.2E-59 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 327 3.5E-30 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 327 7.8E-110 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 188 1.1E-29 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 PANTHER PTHR34069:SF2 2 332 2.0E-126 T 22-04-2016 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 SUPERFAMILY SSF53901 8 327 3.52E-64 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS06685 4a315ff8e4d30da468f001a9d9cc7cd8 332 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 327 65.277 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS12185 594414d234e9445ec650d837e165536d 244 SUPERFAMILY SSF55315 2 76 5.53E-12 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS12185 594414d234e9445ec650d837e165536d 244 Gene3D G3DSA:3.40.1280.10 92 243 6.6E-47 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS12185 594414d234e9445ec650d837e165536d 244 SMART SM00967 6 80 2.2E-13 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 MED134_RS12185 594414d234e9445ec650d837e165536d 244 SUPERFAMILY SSF75217 68 244 3.14E-43 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS12185 594414d234e9445ec650d837e165536d 244 Gene3D G3DSA:3.30.1330.30 2 76 5.1E-14 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS12185 594414d234e9445ec650d837e165536d 244 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 79 1.3E-16 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 MED134_RS12185 594414d234e9445ec650d837e165536d 244 Pfam PF00588 SpoU rRNA Methylase family 97 237 9.0E-36 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS12185 594414d234e9445ec650d837e165536d 244 PANTHER PTHR12029 9 244 1.2E-68 T 22-04-2016 MED134_RS12185 594414d234e9445ec650d837e165536d 244 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 6 243 2.1E-61 T 22-04-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 Pfam PF01872 RibD C-terminal domain 152 293 5.4E-27 T 22-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 295 2.2E-80 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 105 1.2E-19 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 Gene3D G3DSA:3.40.430.10 154 330 1.4E-45 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 Gene3D G3DSA:3.40.140.10 4 153 2.5E-34 T 22-04-2016 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 SUPERFAMILY SSF53927 4 150 1.28E-44 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 SUPERFAMILY SSF53597 152 328 3.67E-38 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain MED134_RS05270 2d689a46e93997278c44f507b5a854ee 333 PANTHER PTHR11079 2 227 2.3E-48 T 22-04-2016 MED134_RS05325 4c4263951c10699efefc973ca50b52a2 131 Gene3D G3DSA:3.30.1460.10 49 127 6.2E-8 T 22-04-2016 MED134_RS05325 4c4263951c10699efefc973ca50b52a2 131 SUPERFAMILY SSF69635 45 127 1.22E-8 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PANTHER PTHR10617 454 508 1.8E-150 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PANTHER PTHR10617 57 370 1.8E-150 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 251 6.9E-8 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 83 105 6.9E-8 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 84 103 2.4E-6 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 257 2.4E-6 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 Gene3D G3DSA:3.50.50.60 437 515 1.6E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 Gene3D G3DSA:3.50.50.60 84 272 1.6E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PANTHER PTHR10617:SF52 454 508 1.8E-150 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PANTHER PTHR10617:SF52 57 370 1.8E-150 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 Pfam PF03486 HI0933-like protein 83 116 9.6E-5 T 22-04-2016 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 SUPERFAMILY SSF51905 83 270 1.3E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 SUPERFAMILY SSF51905 463 514 1.3E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01085 ec6594b21acec8dfddaf6fc98ab10781 518 PIRSF PIRSF038984 2 518 1.2E-193 T 22-04-2016 IPR028348 FAD dependent protein MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 Pfam PF07690 Major Facilitator Superfamily 12 363 1.1E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 Gene3D G3DSA:1.20.1250.20 212 405 7.0E-18 T 22-04-2016 MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 Gene3D G3DSA:1.20.1250.20 10 190 2.4E-15 T 22-04-2016 MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 PANTHER PTHR23514 1 405 4.3E-43 T 22-04-2016 MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 PANTHER PTHR23514:SF3 1 405 4.3E-43 T 22-04-2016 MED134_RS11250 8dd6da34eec019d55d413990f4db3bf5 408 SUPERFAMILY SSF103473 6 403 9.94E-43 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS06170 bf6d068161b778a7620f4ad4258db4ef 296 SUPERFAMILY SSF63825 39 260 3.66E-24 T 22-04-2016 MED134_RS06170 bf6d068161b778a7620f4ad4258db4ef 296 PANTHER PTHR24103:SF208 46 230 8.4E-16 T 22-04-2016 MED134_RS06170 bf6d068161b778a7620f4ad4258db4ef 296 PANTHER PTHR24103 46 230 8.4E-16 T 22-04-2016 MED134_RS06170 bf6d068161b778a7620f4ad4258db4ef 296 Gene3D G3DSA:2.120.10.30 25 272 5.1E-33 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS05680 4ea0f997d9d3d537b67337d714cdc888 149 PANTHER PTHR23091 1 145 2.0E-22 T 22-04-2016 MED134_RS05680 4ea0f997d9d3d537b67337d714cdc888 149 PANTHER PTHR23091:SF259 1 145 2.0E-22 T 22-04-2016 MED134_RS05680 4ea0f997d9d3d537b67337d714cdc888 149 Gene3D G3DSA:3.40.630.30 1 142 1.0E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS05680 4ea0f997d9d3d537b67337d714cdc888 149 SUPERFAMILY SSF55729 3 146 3.76E-32 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS05680 4ea0f997d9d3d537b67337d714cdc888 149 Pfam PF00583 Acetyltransferase (GNAT) family 57 137 3.1E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 468 489 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 330 345 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 407 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 417 436 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 88 111 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 159 171 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 354 375 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 116 140 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 5.1E-73 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 514 2.2E-135 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 Gene3D G3DSA:1.20.210.10 14 582 2.1E-180 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PANTHER PTHR10422 12 597 2.3E-209 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 PANTHER PTHR10422:SF6 12 597 2.3E-209 T 22-04-2016 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 SUPERFAMILY SSF81442 22 560 6.28E-151 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS11225 c1915fa727ed37275441184dee337b11 607 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 286 340 - T 22-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 PANTHER PTHR23152 5 910 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Gene3D G3DSA:3.40.50.970 140 521 5.9E-66 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 PANTHER PTHR23152:SF4 5 910 0.0 T 22-04-2016 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 5 43 1.5E-13 T 22-04-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 775 910 2.2E-41 T 22-04-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 SUPERFAMILY SSF52518 98 519 9.81E-80 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Pfam PF02779 Transketolase, pyrimidine binding domain 577 771 1.3E-58 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Pfam PF00676 Dehydrogenase E1 component 187 504 1.1E-52 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 6 909 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 SMART SM00861 578 770 7.5E-43 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 PIRSF PIRSF000157 1 912 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 SUPERFAMILY SSF52518 560 776 1.77E-47 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS07635 2c7d9aefeea4f39674c31d4417b3039a 915 Gene3D G3DSA:3.40.50.970 591 778 2.3E-22 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Pfam PF16657 Maltogenic Amylase, C-terminal domain 484 541 1.7E-8 T 22-04-2016 IPR032091 Maltogenic Amylase, C-terminal MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 SUPERFAMILY SSF51445 5 481 5.37E-144 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 SMART SM00642 15 422 2.9E-131 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Gene3D G3DSA:2.60.40.1180 485 562 3.3E-19 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Pfam PF00128 Alpha amylase, catalytic domain 30 379 2.9E-112 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 PANTHER PTHR10357:SF142 460 562 3.7E-207 T 22-04-2016 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 PANTHER PTHR10357:SF142 1 427 3.7E-207 T 22-04-2016 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 SUPERFAMILY SSF51011 484 562 3.6E-16 T 22-04-2016 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Gene3D G3DSA:3.20.20.80 178 483 2.0E-123 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Gene3D G3DSA:3.20.20.80 4 106 2.0E-123 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 PANTHER PTHR10357 460 562 3.7E-207 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 PANTHER PTHR10357 1 427 3.7E-207 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS00960 8644bfd3f4326987c7b825c9612a5a35 564 Gene3D G3DSA:3.90.400.10 107 177 5.4E-22 T 22-04-2016 MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PANTHER PTHR24321:SF6 91 228 1.1E-20 T 22-04-2016 MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PANTHER PTHR24321 91 228 1.1E-20 T 22-04-2016 MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 Gene3D G3DSA:3.40.50.720 2 227 1.5E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 210 1.5E-21 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 154 1.5E-21 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 172 1.5E-21 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-21 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 SUPERFAMILY SSF51735 3 228 2.85E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14065 1211de7536c427cb5daa62bddadf7a54 232 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 62 227 4.3E-40 T 22-04-2016 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 601 618 - T 22-04-2016 IPR010917 TonB-dependent receptor, conserved site MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 Gene3D G3DSA:2.40.170.20 155 618 3.0E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 142 1.1E-12 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 PANTHER PTHR32552:SF31 6 618 3.4E-21 T 22-04-2016 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 Gene3D G3DSA:2.170.130.10 45 145 2.3E-16 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 SUPERFAMILY SSF56935 41 618 4.81E-74 T 22-04-2016 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 PANTHER PTHR32552 6 618 3.4E-21 T 22-04-2016 MED134_RS03230 0b63ec938273dc8b4c219d11eb0b8412 618 Pfam PF00593 TonB dependent receptor 387 616 6.2E-31 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Gene3D G3DSA:2.70.98.10 32 328 1.5E-93 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 SUPERFAMILY SSF48208 268 712 1.05E-29 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Gene3D G3DSA:2.60.120.260 829 956 2.8E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Gene3D G3DSA:3.30.2080.10 590 733 1.8E-67 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 759 816 2.9E-5 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 PANTHER PTHR12143 10 372 4.2E-219 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 PANTHER PTHR12143 392 732 4.2E-219 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 SUPERFAMILY SSF49785 830 958 3.02E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Gene3D G3DSA:1.20.1610.10 442 589 6.6E-62 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Pfam PF00754 F5/8 type C domain 839 962 4.1E-11 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 22 728 1.6E-203 T 22-04-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Pfam PF07971 Glycosyl hydrolase family 92 245 724 6.1E-179 T 22-04-2016 IPR012939 Glycosyl hydrolase family 92 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 PANTHER PTHR12143:SF22 10 372 4.2E-219 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 PANTHER PTHR12143:SF22 392 732 4.2E-219 T 22-04-2016 MED134_RS06765 480ac5f85dd388996dcbdc2ba0db8ef6 982 Gene3D G3DSA:1.20.1050.60 352 440 2.4E-35 T 22-04-2016 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 Gene3D G3DSA:3.20.20.70 3 290 4.9E-87 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 4.9E-11 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 4.9E-11 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 4.9E-11 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 4.9E-11 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PANTHER PTHR12128:SF15 1 290 3.4E-76 T 22-04-2016 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 SMART SM01130 4 291 5.8E-81 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 Pfam PF00701 Dihydrodipicolinate synthetase family 6 290 6.7E-57 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 SUPERFAMILY SSF51569 5 290 2.83E-79 T 22-04-2016 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PANTHER PTHR12128 1 290 3.4E-76 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS07785 aeed14b79a1a7c8ca43151e59ff216bc 304 PIRSF PIRSF001365 1 299 1.8E-78 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 PRINTS PR00625 DnaJ domain signature 194 212 4.2E-13 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 PRINTS PR00625 DnaJ domain signature 212 227 4.2E-13 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 PRINTS PR00625 DnaJ domain signature 234 254 4.2E-13 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 Pfam PF00226 DnaJ domain 193 252 8.1E-16 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 Pfam PF05099 Tellurite resistance protein TerB 49 183 1.2E-29 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 PANTHER PTHR24078 140 247 9.8E-17 T 22-04-2016 MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 Gene3D G3DSA:1.10.3680.10 18 192 1.3E-23 T 22-04-2016 IPR029024 TerB-like MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 PANTHER PTHR24078:SF180 140 247 9.8E-17 T 22-04-2016 MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 SUPERFAMILY SSF46565 186 250 7.18E-18 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 SUPERFAMILY SSF158682 18 206 6.54E-28 T 22-04-2016 IPR029024 TerB-like MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 SMART SM00271 191 254 4.3E-16 T 22-04-2016 IPR001623 DnaJ domain MED134_RS08585 b51f52d4c70add4becfc8ce46335d6f6 255 Gene3D G3DSA:1.10.287.110 193 251 4.9E-17 T 22-04-2016 IPR001623 DnaJ domain MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 PANTHER PTHR10173:SF34 41 196 3.9E-63 T 22-04-2016 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 PANTHER PTHR10173 41 196 3.9E-63 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 Pfam PF01625 Peptide methionine sulfoxide reductase 43 194 5.0E-59 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 41 199 35.051 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 SUPERFAMILY SSF55068 14 202 1.7E-70 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 43 191 4.2E-54 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS05900 dd76a02b45992bb279a2f679f77746c0 218 Gene3D G3DSA:3.30.1060.10 23 193 2.2E-70 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Gene3D G3DSA:1.10.340.30 18 118 2.4E-42 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 PANTHER PTHR10359:SF1 2 321 1.1E-94 T 22-04-2016 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Gene3D G3DSA:1.10.1670.10 119 220 1.6E-40 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 SMART SM00478 35 186 5.9E-49 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Pfam PF00633 Helix-hairpin-helix motif 97 124 5.5E-8 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Gene3D G3DSA:3.90.79.10 228 324 2.3E-9 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 SUPERFAMILY SSF48150 3 218 4.08E-72 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 SUPERFAMILY SSF55811 216 348 1.07E-11 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 3 268 2.5E-98 T 22-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 PANTHER PTHR10359 2 321 1.1E-94 T 22-04-2016 MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Pfam PF14815 NUDIX domain 231 346 1.4E-13 T 22-04-2016 IPR029119 MutY, C-terminal MED134_RS10225 62f970dd5cd9b5f153744742b03f8c01 349 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 150 2.2E-18 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 Pfam PF00338 Ribosomal protein S10p/S20e 6 100 6.3E-37 T 22-04-2016 IPR027486 Ribosomal protein S10 domain MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 SMART SM01403 6 100 2.6E-54 T 22-04-2016 IPR027486 Ribosomal protein S10 domain MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 26.146 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 28 43 - T 22-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 3.8E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 3.8E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 3.8E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 3 101 5.1E-45 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 PANTHER PTHR11700 1 101 2.7E-47 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 Gene3D G3DSA:3.30.70.600 3 101 9.5E-44 T 22-04-2016 IPR027486 Ribosomal protein S10 domain MED134_RS12230 9885e91b077c22019aa53b8e489dfed6 101 SUPERFAMILY SSF54999 4 101 2.75E-37 T 22-04-2016 IPR027486 Ribosomal protein S10 domain MED134_RS12795 b460098a011066543eefd7bbc43eb23f 378 SUPERFAMILY SSF109854 200 364 3.11E-34 T 22-04-2016 MED134_RS12795 b460098a011066543eefd7bbc43eb23f 378 Pfam PF04978 Protein of unknown function (DUF664) 217 357 2.7E-10 T 22-04-2016 IPR007061 Protein of unknown function DUF664 MED134_RS12795 b460098a011066543eefd7bbc43eb23f 378 Gene3D G3DSA:1.20.120.450 195 367 7.2E-64 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS12795 b460098a011066543eefd7bbc43eb23f 378 Gene3D G3DSA:2.60.120.260 25 127 2.3E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS01095 d6404b1f99fa214d3cd230af170728fb 415 PANTHER PTHR11662 38 415 3.5E-14 T 22-04-2016 MED134_RS01095 d6404b1f99fa214d3cd230af170728fb 415 Pfam PF07690 Major Facilitator Superfamily 34 364 1.1E-24 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS01095 d6404b1f99fa214d3cd230af170728fb 415 SUPERFAMILY SSF103473 7 413 2.22E-39 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS01095 d6404b1f99fa214d3cd230af170728fb 415 Gene3D G3DSA:1.20.1250.20 28 208 7.0E-16 T 22-04-2016 MED134_RS01095 d6404b1f99fa214d3cd230af170728fb 415 Gene3D G3DSA:1.20.1250.20 218 410 2.7E-17 T 22-04-2016 MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 135 5.6E-15 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 Gene3D G3DSA:3.40.50.1770 1 192 6.2E-23 T 22-04-2016 MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 SMART SM01003 4 136 3.7E-6 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 SMART SM01002 160 338 0.0073 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 PANTHER PTHR11133:SF14 4 401 6.2E-78 T 22-04-2016 MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 PANTHER PTHR11133 4 401 6.2E-78 T 22-04-2016 MED134_RS13185 6a2f6eade900e6f6470faf8b906985ea 401 SUPERFAMILY SSF52283 1 192 6.29E-16 T 22-04-2016 MED134_RS07845 f3e7dbac30ab2043e8a968180dba09c4 200 Gene3D G3DSA:3.20.20.70 2 197 1.3E-35 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS07845 f3e7dbac30ab2043e8a968180dba09c4 200 SUPERFAMILY SSF51391 5 195 4.45E-18 T 22-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 MED134_RS07845 f3e7dbac30ab2043e8a968180dba09c4 200 Pfam PF02581 Thiamine monophosphate synthase/TENI 4 174 1.8E-9 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 Pfam PF00923 Transaldolase 3 205 2.9E-56 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 PANTHER PTHR10683 1 215 2.6E-72 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 Hamap MF_00494 Probable transaldolase [tal]. 1 218 44.462 T 22-04-2016 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 SUPERFAMILY SSF51569 1 215 1.88E-70 T 22-04-2016 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 Gene3D G3DSA:3.20.20.70 1 215 3.0E-67 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 MED134_RS03100 d869fa86d2dcebc9d63eb1e3b72e5783 218 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 215 2.5E-85 T 22-04-2016 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 MED134_RS05580 6390c945082aed0fd6b6f3dabc258977 668 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 68 218 5.5E-12 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 MED134_RS05580 6390c945082aed0fd6b6f3dabc258977 668 Pfam PF01841 Transglutaminase-like superfamily 317 384 6.3E-5 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS09640 7412bc6705b8f4a8fff9621a712b6e9d 379 SUPERFAMILY SSF117892 94 232 1.11E-8 T 22-04-2016 IPR001107 Band 7 domain MED134_RS09640 7412bc6705b8f4a8fff9621a712b6e9d 379 PANTHER PTHR37826 14 369 3.7E-84 T 22-04-2016 MED134_RS09640 7412bc6705b8f4a8fff9621a712b6e9d 379 PANTHER PTHR37826:SF2 14 369 3.7E-84 T 22-04-2016 MED134_RS09640 7412bc6705b8f4a8fff9621a712b6e9d 379 Pfam PF14237 Domain of unknown function (DUF4339) 316 359 6.8E-19 T 22-04-2016 IPR025640 Domain of unknown function DUF4339 MED134_RS09640 7412bc6705b8f4a8fff9621a712b6e9d 379 Pfam PF13421 SPFH domain-Band 7 family 31 238 8.7E-96 T 22-04-2016 MED134_RS09040 e1cd376d58dbaee70f07a229ccd5e3f6 615 Pfam PF01433 Peptidase family M1 304 394 1.2E-5 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS09040 e1cd376d58dbaee70f07a229ccd5e3f6 615 SUPERFAMILY SSF55486 296 503 1.3E-33 T 22-04-2016 MED134_RS09040 e1cd376d58dbaee70f07a229ccd5e3f6 615 PANTHER PTHR11533 304 498 4.0E-19 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS09040 e1cd376d58dbaee70f07a229ccd5e3f6 615 PANTHER PTHR11533:SF185 304 498 4.0E-19 T 22-04-2016 MED134_RS09040 e1cd376d58dbaee70f07a229ccd5e3f6 615 Gene3D G3DSA:1.10.390.10 371 504 2.8E-19 T 22-04-2016 MED134_RS04235 c81476cdbe3dd2839641ac05de629a98 177 SUPERFAMILY SSF53254 32 145 8.25E-15 T 22-04-2016 IPR029033 Histidine phosphatase superfamily MED134_RS04235 c81476cdbe3dd2839641ac05de629a98 177 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 34 100 3.0E-10 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 MED134_RS04235 c81476cdbe3dd2839641ac05de629a98 177 Gene3D G3DSA:3.40.50.1240 21 86 3.6E-12 T 22-04-2016 IPR029033 Histidine phosphatase superfamily MED134_RS04235 c81476cdbe3dd2839641ac05de629a98 177 Gene3D G3DSA:2.30.40.10 87 167 2.2E-4 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF54791 544 644 4.11E-15 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF00575 S1 RNA binding domain 627 699 1.5E-10 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 PIRSF PIRSF005499 4 736 1.3E-263 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SMART SM00322 555 625 6.9E-10 T 22-04-2016 IPR004087 K Homology domain GO:0003676 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 704 27.522 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SMART SM00316 628 701 6.6E-12 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF55666 140 230 5.47E-23 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF54211 295 491 4.05E-49 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF55666 451 551 1.82E-25 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Gene3D G3DSA:2.40.50.140 632 702 1.9E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05640 b53482b4061bcc342094156ab016a548 742 PANTHER PTHR11252 10 741 0.0 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF50249 618 705 7.68E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05640 b53482b4061bcc342094156ab016a548 742 SUPERFAMILY SSF54211 14 145 5.57E-39 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF00013 KH domain 561 620 3.6E-10 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Gene3D G3DSA:1.10.10.400 230 318 9.4E-21 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF03725 3' exoribonuclease family, domain 2 461 530 3.1E-5 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF03725 3' exoribonuclease family, domain 2 153 211 4.7E-12 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 244 323 1.2E-9 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Gene3D G3DSA:3.30.1370.10 554 631 8.5E-18 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 14 701 2.9E-264 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Gene3D G3DSA:3.30.230.70 14 225 2.0E-72 T 22-04-2016 IPR027408 PNPase/RNase PH domain MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Gene3D G3DSA:3.30.230.70 319 545 2.2E-82 T 22-04-2016 IPR027408 PNPase/RNase PH domain MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF01138 3' exoribonuclease family, domain 1 327 456 2.3E-20 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 MED134_RS05640 b53482b4061bcc342094156ab016a548 742 Pfam PF01138 3' exoribonuclease family, domain 1 15 145 1.8E-18 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 SUPERFAMILY SSF55931 455 604 5.79E-76 T 22-04-2016 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 SUPERFAMILY SSF55931 176 409 5.79E-76 T 22-04-2016 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 PANTHER PTHR20852:SF14 196 413 3.1E-75 T 22-04-2016 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 Gene3D G3DSA:3.30.590.10 455 597 8.5E-89 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 Gene3D G3DSA:3.30.590.10 195 409 8.5E-89 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 SMART SM01230 197 473 7.1E-41 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 Pfam PF12437 Glutamine synthetase type III N terminal 28 185 4.5E-74 T 22-04-2016 IPR022147 Glutamine synthetase type III N-terminal GO:0004356 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 330 345 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 PANTHER PTHR20852 196 413 3.1E-75 T 22-04-2016 MED134_RS03830 71e98b5498da7e29a79d594f8861c36e 727 Pfam PF00120 Glutamine synthetase, catalytic domain 206 385 2.3E-19 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 PANTHER PTHR30055 2 138 1.5E-17 T 22-04-2016 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 1.5E-13 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 SUPERFAMILY SSF48498 73 186 1.85E-5 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 7.2E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 7.2E-9 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 PANTHER PTHR30055:SF47 2 138 1.5E-17 T 22-04-2016 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 SUPERFAMILY SSF46689 2 75 3.45E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS07395 b020cc07af284df76b223784ceb90fa8 201 Gene3D G3DSA:1.10.357.10 2 187 1.4E-25 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 SMART SM00116 273 320 0.36 T 22-04-2016 IPR000644 CBS domain MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 SMART SM00116 209 256 1.6 T 22-04-2016 IPR000644 CBS domain MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 PANTHER PTHR38418 5 316 7.8E-41 T 22-04-2016 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 Pfam PF01380 SIS domain 41 171 4.2E-27 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 SUPERFAMILY SSF53697 10 320 1.6E-59 T 22-04-2016 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 PIRSF PIRSF004692 2 321 7.3E-120 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 Gene3D G3DSA:3.10.580.10 192 317 3.2E-33 T 22-04-2016 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 Gene3D G3DSA:3.40.50.10490 11 191 1.3E-45 T 22-04-2016 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 311 4.5E-93 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 Pfam PF00571 CBS domain 202 256 6.5E-6 T 22-04-2016 IPR000644 CBS domain MED134_RS04995 a8fe12610c5157deea091fada085fcbd 321 Pfam PF00571 CBS domain 267 317 3.7E-8 T 22-04-2016 IPR000644 CBS domain MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 PANTHER PTHR12737:SF21 2 313 6.9E-88 T 22-04-2016 MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 Pfam PF02274 Amidinotransferase 12 309 5.8E-81 T 22-04-2016 MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 PIRSF PIRSF028188 1 312 1.2E-116 T 22-04-2016 IPR014541 Predicted amidinotransferase, FN0238 type MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 SUPERFAMILY SSF55909 7 306 6.62E-44 T 22-04-2016 MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 PANTHER PTHR12737 2 313 6.9E-88 T 22-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 MED134_RS05470 c4370e41b3d3d9883d328c8b5dc72649 313 Gene3D G3DSA:3.75.10.10 43 305 6.1E-21 T 22-04-2016 MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 PANTHER PTHR10314 1 343 1.1E-121 T 22-04-2016 MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 310 2.4E-70 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 Gene3D G3DSA:3.40.50.1100 157 328 2.4E-67 T 22-04-2016 MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 Gene3D G3DSA:3.40.50.1100 5 46 2.4E-67 T 22-04-2016 MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 Gene3D G3DSA:3.40.50.1100 47 151 4.0E-32 T 22-04-2016 MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 SUPERFAMILY SSF53686 7 331 5.63E-90 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS14270 25e15c3acaaae2efd4b5048f0bb8a9c1 346 PANTHER PTHR10314:SF8 1 343 1.1E-121 T 22-04-2016 MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 PIRSF PIRSF004553 1 181 3.8E-42 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 SUPERFAMILY SSF53335 3 169 4.25E-38 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 PANTHER PTHR18895 15 186 4.4E-26 T 22-04-2016 MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 Gene3D G3DSA:3.40.50.150 1 182 7.2E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 Pfam PF03602 Conserved hypothetical protein 95 2 177 5.2E-37 T 22-04-2016 MED134_RS01290 eb282c04305997b2eae017cbb087a50d 186 PANTHER PTHR18895:SF60 15 186 4.4E-26 T 22-04-2016 MED134_RS12090 27f77262e1febf4c2a364f8e55789811 234 Pfam PF03575 Peptidase family S51 5 208 1.4E-48 T 22-04-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 MED134_RS12090 27f77262e1febf4c2a364f8e55789811 234 Gene3D G3DSA:3.40.50.880 4 227 1.4E-66 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12090 27f77262e1febf4c2a364f8e55789811 234 PANTHER PTHR20842 1 228 6.3E-86 T 22-04-2016 MED134_RS12090 27f77262e1febf4c2a364f8e55789811 234 SUPERFAMILY SSF52317 5 221 1.27E-37 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12090 27f77262e1febf4c2a364f8e55789811 234 PANTHER PTHR20842:SF2 1 228 6.3E-86 T 22-04-2016 MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 Gene3D G3DSA:3.40.50.150 90 279 5.3E-36 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 PIRSF PIRSF000401 13 286 4.0E-48 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 47 284 5.8E-46 T 22-04-2016 MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 PANTHER PTHR18895:SF3 8 285 7.0E-38 T 22-04-2016 MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 SUPERFAMILY SSF53335 58 280 2.05E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13505 329bbbced4217b9ec9960358e6c179ee 286 PANTHER PTHR18895 8 285 7.0E-38 T 22-04-2016 MED134_RS14250 49897c29935254996d4c1e449f6da023 339 Gene3D G3DSA:3.40.640.10 3 249 2.0E-85 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS14250 49897c29935254996d4c1e449f6da023 339 PANTHER PTHR10289:SF5 3 339 8.8E-137 T 22-04-2016 MED134_RS14250 49897c29935254996d4c1e449f6da023 339 PANTHER PTHR10289 3 339 8.8E-137 T 22-04-2016 MED134_RS14250 49897c29935254996d4c1e449f6da023 339 SUPERFAMILY SSF53383 3 338 1.79E-114 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS14250 49897c29935254996d4c1e449f6da023 339 Gene3D G3DSA:3.90.1150.10 250 338 9.4E-20 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS14250 49897c29935254996d4c1e449f6da023 339 PIRSF PIRSF017617 1 339 1.0E-131 T 22-04-2016 IPR023603 Threonine aldolase MED134_RS14250 49897c29935254996d4c1e449f6da023 339 Pfam PF01212 Beta-eliminating lyase 4 287 1.2E-84 T 22-04-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 SUPERFAMILY SSF47203 244 388 2.58E-43 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 PANTHER PTHR10909 6 392 2.9E-182 T 22-04-2016 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Gene3D G3DSA:1.10.540.10 8 131 6.5E-40 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 PANTHER PTHR10909:SF307 6 392 2.9E-182 T 22-04-2016 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Gene3D G3DSA:1.20.140.10 226 388 1.4E-48 T 22-04-2016 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 131 1.3E-33 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Gene3D G3DSA:2.40.110.10 135 225 3.9E-30 T 22-04-2016 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 226 6.3E-18 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 SUPERFAMILY SSF56645 6 236 2.09E-72 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MED134_RS07580 7d222968114d72a9575c61d7ea26aada 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 380 4.0E-33 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS03175 a362000961b49065c5c9ffc2ac91828f 157 Pfam PF13508 Acetyltransferase (GNAT) domain 50 134 3.2E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS03175 a362000961b49065c5c9ffc2ac91828f 157 Gene3D G3DSA:3.40.630.30 3 153 1.2E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS03175 a362000961b49065c5c9ffc2ac91828f 157 PANTHER PTHR23091 3 155 2.1E-38 T 22-04-2016 MED134_RS03175 a362000961b49065c5c9ffc2ac91828f 157 PANTHER PTHR23091:SF265 3 155 2.1E-38 T 22-04-2016 MED134_RS03175 a362000961b49065c5c9ffc2ac91828f 157 SUPERFAMILY SSF55729 4 140 2.99E-27 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 SUPERFAMILY SSF74650 5 236 4.08E-52 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 401 408 - T 22-04-2016 IPR030458 Glycosyl hydrolases family 31, active site MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 Pfam PF01055 Glycosyl hydrolases family 31 230 673 4.3E-152 T 22-04-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 SUPERFAMILY SSF51445 239 587 4.92E-96 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 PANTHER PTHR22762 27 800 2.8E-247 T 22-04-2016 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 Pfam PF16338 Domain of unknown function (DUF4968) 24 118 2.0E-22 T 22-04-2016 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 Pfam PF17137 Domain of unknown function (DUF5110) 690 756 2.1E-7 T 22-04-2016 IPR033403 Domain of unknown function DUF5110 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 PANTHER PTHR22762:SF7 27 800 2.8E-247 T 22-04-2016 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 SUPERFAMILY SSF51011 589 669 6.04E-20 T 22-04-2016 MED134_RS04460 34314ef6d0af5a6902b8fcfa339408db 800 Pfam PF13802 Galactose mutarotase-like 144 209 1.1E-20 T 22-04-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain MED134_RS03535 1b7fcff90b77744781054a026809a765 132 PANTHER PTHR11049:SF13 1 126 7.3E-51 T 22-04-2016 MED134_RS03535 1b7fcff90b77744781054a026809a765 132 PANTHER PTHR11049 1 126 7.3E-51 T 22-04-2016 MED134_RS03535 1b7fcff90b77744781054a026809a765 132 Gene3D G3DSA:3.10.129.10 3 121 7.6E-23 T 22-04-2016 IPR029069 HotDog domain MED134_RS03535 1b7fcff90b77744781054a026809a765 132 Pfam PF03061 Thioesterase superfamily 17 92 5.9E-13 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS03535 1b7fcff90b77744781054a026809a765 132 SUPERFAMILY SSF54637 4 122 4.98E-24 T 22-04-2016 IPR029069 HotDog domain MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 7.4E-33 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 7.4E-33 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 90 106 7.4E-33 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 7.4E-33 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 113 132 7.4E-33 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 SMART SM00562 2 136 5.2E-69 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 Gene3D G3DSA:3.30.70.141 2 136 4.2E-56 T 22-04-2016 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 SUPERFAMILY SSF54919 1 136 4.32E-53 T 22-04-2016 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 Pfam PF00334 Nucleoside diphosphate kinase 3 136 1.1E-51 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 PANTHER PTHR11349 4 127 1.5E-62 T 22-04-2016 MED134_RS13580 433bc98f94571f3f956b681a6435a876 138 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 31.597 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 Pfam PF00691 OmpA family 101 162 2.2E-7 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 Pfam PF00691 OmpA family 217 309 6.0E-17 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 SUPERFAMILY SSF103088 208 315 2.88E-27 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 Gene3D G3DSA:3.30.1330.60 211 315 6.1E-27 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 Gene3D G3DSA:3.30.1330.60 66 175 3.4E-11 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 PANTHER PTHR30128 211 315 4.4E-25 T 22-04-2016 MED134_RS09660 314fe78bda3860bfbf4276e59c662886 316 SUPERFAMILY SSF103088 65 161 1.29E-9 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 SUPERFAMILY SSF51735 5 176 1.49E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 SUPERFAMILY SSF48179 179 468 2.61E-111 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 1.3E-81 T 22-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 Gene3D G3DSA:1.20.5.320 436 467 1.1E-19 T 22-04-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 SMART SM01350 180 468 1.5E-170 T 22-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 Gene3D G3DSA:1.10.1040.10 182 434 9.4E-95 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 468 6.0E-179 T 22-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 467 3.4E-115 T 22-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PANTHER PTHR11811:SF25 1 469 4.3E-233 T 22-04-2016 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 Gene3D G3DSA:3.40.50.720 3 180 9.3E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PANTHER PTHR11811 1 469 4.3E-233 T 22-04-2016 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 170 2.3E-44 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MED134_RS14020 3aebfc7a0b1e3ba1f09bfa69c1196519 469 PIRSF PIRSF000109 1 469 1.3E-183 T 22-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 MED134_RS03960 d24e8adf3c0d70ebb8c7f5946559a601 336 Pfam PF13240 zinc-ribbon domain 32 52 1.6E-6 T 22-04-2016 IPR026870 Zinc-ribbon domain MED134_RS03960 d24e8adf3c0d70ebb8c7f5946559a601 336 Pfam PF12412 Protein of unknown function (DUF3667) 75 117 1.9E-12 T 22-04-2016 IPR022134 Protein of unknown function DUF3667 MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 PANTHER PTHR23150 258 369 1.1E-30 T 22-04-2016 MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 PANTHER PTHR23150 54 181 1.1E-30 T 22-04-2016 MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 Gene3D G3DSA:3.90.1580.10 498 547 9.3E-96 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 Gene3D G3DSA:3.90.1580.10 51 178 9.3E-96 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 Gene3D G3DSA:3.90.1580.10 257 375 9.3E-96 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 SUPERFAMILY SSF56436 492 540 3.77E-60 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 SUPERFAMILY SSF56436 57 178 3.77E-60 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 SUPERFAMILY SSF56436 257 369 3.77E-60 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 Pfam PF03781 Sulfatase-modifying factor enzyme 1 59 378 2.5E-41 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 TIGRFAM TIGR03524 GldJ: gliding motility-associated lipoprotein GldJ 5 553 5.4E-292 T 22-04-2016 IPR019865 Gliding motility-associated lipoprotein GldJ MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 PANTHER PTHR23150:SF19 258 369 1.1E-30 T 22-04-2016 MED134_RS11875 42d3b2b4e45282288ba15c235770940d 553 PANTHER PTHR23150:SF19 54 181 1.1E-30 T 22-04-2016 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Gene3D G3DSA:3.40.50.300 328 529 4.0E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Gene3D G3DSA:3.40.50.300 125 279 4.8E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Gene3D G3DSA:3.40.50.300 1 88 4.8E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Pfam PF12848 ABC transporter 231 310 1.2E-22 T 22-04-2016 IPR032781 ABC-transporter extension domain MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 SUPERFAMILY SSF52540 133 255 5.9E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 SUPERFAMILY SSF52540 2 92 5.9E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 SUPERFAMILY SSF52540 306 531 3.58E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 PANTHER PTHR19211 1 536 4.6E-286 T 22-04-2016 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 PANTHER PTHR19211:SF60 1 536 4.6E-286 T 22-04-2016 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Pfam PF00005 ABC transporter 18 192 3.4E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 Pfam PF00005 ABC transporter 344 473 6.4E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 SMART SM00382 26 244 1.8E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS14035 c998e4fbfb590efd0b59b80e2cfb3f28 546 SMART SM00382 352 518 3.9E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 Gene3D G3DSA:3.40.50.150 163 397 1.0E-36 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 160 176 1.4E-17 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 266 278 1.4E-17 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 1.4E-17 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 184 198 1.4E-17 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PANTHER PTHR30195 1 396 3.1E-157 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PANTHER PTHR30195 431 537 3.1E-157 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 SUPERFAMILY SSF53335 6 415 2.78E-107 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 SUPERFAMILY SSF53335 470 542 2.78E-107 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 Pfam PF02384 N-6 DNA Methylase 139 402 1.6E-54 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 Pfam PF12161 HsdM N-terminal domain 7 130 3.8E-11 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PANTHER PTHR30195:SF12 1 396 3.1E-157 T 22-04-2016 MED134_RS00375 2aa8c274bf2ca523ae4b0ce9df4b6f5a 544 PANTHER PTHR30195:SF12 431 537 3.1E-157 T 22-04-2016 MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 SUPERFAMILY SSF54631 195 328 6.06E-24 T 22-04-2016 MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 Gene3D G3DSA:3.10.580.10 194 328 7.2E-14 T 22-04-2016 MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 Pfam PF01595 Domain of unknown function DUF21 9 192 7.5E-27 T 22-04-2016 IPR002550 Domain of unknown function DUF21 MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 Pfam PF00571 CBS domain 277 327 3.6E-4 T 22-04-2016 IPR000644 CBS domain MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 PANTHER PTHR22777:SF4 1 358 4.4E-108 T 22-04-2016 MED134_RS08720 a1cc34045d427ba3ebd53ff825658e93 367 PANTHER PTHR22777 1 358 4.4E-108 T 22-04-2016 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 SUPERFAMILY SSF54292 237 353 1.62E-24 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 SUPERFAMILY SSF63380 3 103 1.42E-24 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Gene3D G3DSA:2.40.30.10 4 94 3.7E-25 T 22-04-2016 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 55 62 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 91 105 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 116 135 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 212 220 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 153 164 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00406 Cytochrome B5 reductase signature 34 45 9.1E-10 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Gene3D G3DSA:3.10.20.30 239 353 3.4E-26 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 347 6.9E-14 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 304 312 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PANTHER PTHR19370 4 264 5.2E-60 T 22-04-2016 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Pfam PF00970 Oxidoreductase FAD-binding domain 8 103 6.3E-15 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PANTHER PTHR19370:SF93 4 264 5.2E-60 T 22-04-2016 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 6.2E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 55 62 6.2E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 220 6.2E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 164 6.2E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 SUPERFAMILY SSF52343 94 242 1.57E-33 T 22-04-2016 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Pfam PF00175 Oxidoreductase NAD-binding domain 119 223 2.3E-16 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 356 8.5E-131 T 22-04-2016 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00930 MED134_RS11485 82947efffa40fb80a3cda80c3b47a6f7 357 Gene3D G3DSA:3.40.50.80 95 238 8.4E-39 T 22-04-2016 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 Pfam PF00459 Inositol monophosphatase family 8 257 7.2E-42 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 Gene3D G3DSA:3.40.190.80 163 265 8.0E-36 T 22-04-2016 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 PANTHER PTHR20854 9 264 2.4E-63 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 PANTHER PTHR20854:SF5 9 264 2.4E-63 T 22-04-2016 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 5.7E-6 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 5.7E-6 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 223 247 5.7E-6 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 11 264 2.5E-71 T 22-04-2016 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 Gene3D G3DSA:3.30.540.10 7 130 5.1E-36 T 22-04-2016 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 SUPERFAMILY SSF56655 7 259 8.25E-59 T 22-04-2016 MED134_RS01360 e99c5ca64b61c2d1cf559fb2a94e2aee 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 22-04-2016 IPR020583 Inositol monophosphatase, metal-binding site MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 TIGRFAM TIGR00510 lipA: lipoyl synthase 9 288 2.8E-110 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 SUPERFAMILY SSF102114 25 286 6.41E-58 T 22-04-2016 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 Gene3D G3DSA:3.20.20.70 29 288 1.1E-63 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 PANTHER PTHR10949 9 286 5.3E-153 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 SMART SM00729 61 268 2.8E-13 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 Pfam PF04055 Radical SAM superfamily 67 226 1.0E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 PIRSF PIRSF005963 1 291 1.0E-129 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS05870 7ef72937a6f51ff6eeb600ff4642ac70 291 Hamap MF_00206 Lipoyl synthase [lipA]. 1 291 131.035 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS00925 a301dcaa2c2cd77e6ef4e590c026c249 111 Pfam PF13239 2TM domain 9 97 5.4E-23 T 22-04-2016 IPR025698 2TM domain MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 SUPERFAMILY SSF53720 34 504 1.09E-123 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 Gene3D G3DSA:3.40.309.10 283 464 9.6E-47 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 PANTHER PTHR11699:SF144 3 516 3.1E-265 T 22-04-2016 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 PANTHER PTHR11699 3 516 3.1E-265 T 22-04-2016 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 Gene3D G3DSA:3.40.605.10 34 282 9.9E-72 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 Pfam PF00171 Aldehyde dehydrogenase family 37 498 7.4E-122 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS09670 70aba1f1b873c4acb2004db46d921af4 517 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 256 2.0E-66 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 PANTHER PTHR11941 1 256 3.2E-93 T 22-04-2016 MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 Gene3D G3DSA:3.90.226.10 1 253 2.8E-87 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 PANTHER PTHR11941:SF54 1 256 3.2E-93 T 22-04-2016 MED134_RS08620 5c27a943d8c5c556e311d2a1a2b5f98e 256 SUPERFAMILY SSF52096 1 256 3.17E-86 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 Gene3D G3DSA:1.25.40.10 408 484 5.6E-28 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 Gene3D G3DSA:1.25.40.10 207 314 5.6E-28 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 SUPERFAMILY SSF48452 26 327 1.39E-77 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 SUPERFAMILY SSF48452 395 538 1.39E-77 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 Pfam PF07980 SusD family 282 538 1.1E-19 T 22-04-2016 IPR012944 RagB/SusD domain MED134_RS10650 47afd1d63e796ab6d60ef5dd2a762081 538 Pfam PF14322 Starch-binding associating with outer membrane 50 225 1.1E-11 T 22-04-2016 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 Gene3D G3DSA:1.10.10.60 239 282 1.2E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 SMART SM00342 196 279 1.9E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 SUPERFAMILY SSF46689 233 281 5.38E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 PANTHER PTHR11019 28 287 8.1E-26 T 22-04-2016 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 SUPERFAMILY SSF51215 28 161 7.06E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 PANTHER PTHR11019:SF11 28 287 8.1E-26 T 22-04-2016 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 Gene3D G3DSA:2.60.120.280 19 158 2.2E-4 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 Gene3D G3DSA:1.10.10.60 175 231 7.1E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00545 6e979d86c277f584c6781cbce078a5a0 296 Pfam PF12833 Helix-turn-helix domain 202 280 1.9E-16 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 38 155 3.3E-14 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 Gene3D G3DSA:3.40.50.720 227 279 2.3E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 Gene3D G3DSA:3.40.50.720 35 194 2.3E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 PANTHER PTHR22604 1 191 5.8E-117 T 22-04-2016 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 PANTHER PTHR22604 209 431 5.8E-117 T 22-04-2016 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 SUPERFAMILY SSF55347 164 351 3.71E-14 T 22-04-2016 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 PANTHER PTHR22604:SF101 1 191 5.8E-117 T 22-04-2016 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 PANTHER PTHR22604:SF101 209 431 5.8E-117 T 22-04-2016 MED134_RS08615 68ae1eacb71159b668814c6cc04329fa 470 SUPERFAMILY SSF51735 29 188 1.46E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10520 54f8a629a415f3789462564a08eb76bc 312 Pfam PF08787 Alginate lyase 58 312 2.8E-42 T 22-04-2016 IPR014895 Alginate lyase 2 MED134_RS10520 54f8a629a415f3789462564a08eb76bc 312 Gene3D G3DSA:2.60.120.200 57 312 1.0E-47 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS10520 54f8a629a415f3789462564a08eb76bc 312 SUPERFAMILY SSF49899 58 312 5.93E-18 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Gene3D G3DSA:4.10.320.10 131 167 7.1E-15 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 PANTHER PTHR23151 2 407 1.7E-181 T 22-04-2016 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Pfam PF02817 e3 binding domain 131 161 1.7E-9 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 407 2.4E-142 T 22-04-2016 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|UniPathway: UPA00868 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 PANTHER PTHR23151:SF47 2 407 1.7E-181 T 22-04-2016 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Gene3D G3DSA:3.30.559.10 174 406 9.0E-84 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Gene3D G3DSA:2.40.50.100 2 84 7.8E-23 T 22-04-2016 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 SUPERFAMILY SSF52777 180 406 1.11E-81 T 22-04-2016 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Pfam PF00364 Biotin-requiring enzyme 4 75 5.9E-19 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 SUPERFAMILY SSF51230 1 84 1.7E-22 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 SUPERFAMILY SSF47005 129 165 1.03E-8 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS07630 cdd8799b5e688f13509a9dd28f50b4e7 416 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 179 406 6.2E-76 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 165 179 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 719 733 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 336 2.7E-62 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 683 882 5.2E-28 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:1.10.1030.10 401 537 8.1E-49 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SUPERFAMILY SSF56059 683 927 3.89E-86 T 22-04-2016 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PANTHER PTHR11405 1 924 0.0 T 22-04-2016 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.40.50.20 4 108 4.6E-37 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PANTHER PTHR11405:SF5 1 924 0.0 T 22-04-2016 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.30.470.20 201 400 4.4E-73 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.30.470.20 759 937 3.7E-55 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 943 0.0 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SMART SM01209 689 851 0.0088 T 22-04-2016 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.30.1490.20 142 200 2.1E-16 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.30.1490.20 696 758 2.8E-20 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SUPERFAMILY SSF56059 129 402 9.37E-100 T 22-04-2016 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 426 546 5.6E-39 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SMART SM01096 423 546 1.5E-58 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SUPERFAMILY SSF52440 1 128 4.89E-41 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SUPERFAMILY SSF52440 567 684 1.58E-47 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 205 224 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 381 399 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 240 257 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 169 181 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 299 328 7.6E-61 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 SUPERFAMILY SSF48108 398 551 1.22E-44 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 Gene3D G3DSA:3.40.50.20 538 672 2.2E-55 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS03265 321755e3bcf639ad75fa8d4daeef118a 950 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 848 855 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS02265 18987394699441876aace62e3444a5a5 191 Gene3D G3DSA:3.90.950.10 1 189 3.6E-63 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like MED134_RS02265 18987394699441876aace62e3444a5a5 191 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 190 42.18 T 22-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 MED134_RS02265 18987394699441876aace62e3444a5a5 191 SUPERFAMILY SSF52972 1 189 6.02E-58 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like MED134_RS02265 18987394699441876aace62e3444a5a5 191 PANTHER PTHR11067:SF9 1 191 6.0E-62 T 22-04-2016 MED134_RS02265 18987394699441876aace62e3444a5a5 191 PANTHER PTHR11067 1 191 6.0E-62 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 MED134_RS02265 18987394699441876aace62e3444a5a5 191 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 188 1.9E-49 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 MED134_RS02265 18987394699441876aace62e3444a5a5 191 Pfam PF01725 Ham1 family 3 186 2.3E-49 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 PANTHER PTHR33797:SF1 1 137 8.6E-48 T 22-04-2016 MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 Gene3D G3DSA:3.30.300.20 4 137 1.4E-44 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 135 1.6E-52 T 22-04-2016 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 PANTHER PTHR33797 1 137 8.6E-48 T 22-04-2016 MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 SUPERFAMILY SSF82784 1 136 7.59E-33 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS09650 566c0800adaa9ce6be96cb8f3877a0e0 138 Pfam PF02566 OsmC-like protein 43 134 1.4E-17 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 82 15.004 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 81 2.0E-18 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 PANTHER PTHR33398 1 83 8.9E-20 T 22-04-2016 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 SUPERFAMILY SSF46992 3 83 4.45E-21 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 65 1.0E-9 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 Pfam PF01649 Ribosomal protein S20 2 80 2.3E-24 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13935 203450dca5001e92ef56c561bbfcd8f5 83 Gene3D G3DSA:1.20.58.110 1 83 4.0E-23 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 PANTHER PTHR13929 3 297 1.8E-58 T 22-04-2016 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 Pfam PF01040 UbiA prenyltransferase family 24 271 1.8E-35 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 PANTHER PTHR13929:SF0 3 297 1.8E-58 T 22-04-2016 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 298 20.1 T 22-04-2016 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 296 4.8E-76 T 22-04-2016 MED134_RS13975 876bcbdfedf2580f9a905df50bc50f2b 300 PIRSF PIRSF005355 1 300 1.4E-71 T 22-04-2016 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 MED134_RS05320 0148efe4aff70f133f011ca73c41dbf5 251 Gene3D G3DSA:2.10.109.10 133 210 6.2E-4 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain MED134_RS05320 0148efe4aff70f133f011ca73c41dbf5 251 Gene3D G3DSA:1.10.260.40 4 65 1.4E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS05320 0148efe4aff70f133f011ca73c41dbf5 251 Pfam PF01381 Helix-turn-helix 8 62 3.7E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS05320 0148efe4aff70f133f011ca73c41dbf5 251 SUPERFAMILY SSF47413 2 66 3.94E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS05320 0148efe4aff70f133f011ca73c41dbf5 251 SMART SM00530 7 62 2.9E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 Pfam PF00512 His Kinase A (phospho-acceptor) domain 122 186 1.3E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 Gene3D G3DSA:3.30.565.10 195 344 5.0E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 Gene3D G3DSA:1.10.287.130 113 179 3.0E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 PANTHER PTHR24423 100 351 3.9E-69 T 22-04-2016 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 6.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 287 6.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 301 6.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 6.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 346 1.9E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 SUPERFAMILY SSF55874 177 344 2.23E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 SMART SM00387 235 348 1.0E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 SMART SM00388 121 188 2.2E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS10765 8ae0aab8357169e7c925a3e7479c4406 351 SUPERFAMILY SSF47384 111 189 8.24E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 Gene3D G3DSA:3.30.470.10 1 115 2.6E-26 T 22-04-2016 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 PANTHER PTHR11825 1 261 4.7E-38 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 PANTHER PTHR11825:SF55 1 261 4.7E-38 T 22-04-2016 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 SUPERFAMILY SSF56752 2 274 1.18E-55 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 Pfam PF01063 Amino-transferase class IV 28 256 1.6E-48 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS04545 8dfaff5a705043b8068a44e30aa67a2a 281 Gene3D G3DSA:3.20.10.10 144 274 1.7E-31 T 22-04-2016 MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 PANTHER PTHR33442:SF2 5 335 7.5E-119 T 22-04-2016 MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 Gene3D G3DSA:3.10.310.10 153 322 7.7E-64 T 22-04-2016 MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 Pfam PF05544 Proline racemase 8 332 4.2E-124 T 22-04-2016 IPR008794 Proline racemase family MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 SUPERFAMILY SSF54506 2 332 2.58E-107 T 22-04-2016 MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 PIRSF PIRSF029792 1 335 1.9E-122 T 22-04-2016 IPR008794 Proline racemase family MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 PANTHER PTHR33442 5 335 7.5E-119 T 22-04-2016 MED134_RS07765 fc9fb03aa6741091f395964f7b1cf848 335 Gene3D G3DSA:3.10.310.10 2 152 2.7E-63 T 22-04-2016 MED134_RS03935 f9ab9b2f5c25b0c0792b569fb085f110 163 Gene3D G3DSA:3.60.21.10 3 156 6.2E-26 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS03935 f9ab9b2f5c25b0c0792b569fb085f110 163 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 150 7.0E-25 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type MED134_RS03935 f9ab9b2f5c25b0c0792b569fb085f110 163 PANTHER PTHR11124 1 133 3.1E-16 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 MED134_RS03935 f9ab9b2f5c25b0c0792b569fb085f110 163 SUPERFAMILY SSF56300 1 161 1.22E-28 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS13125 c0e5096abf032ac846752afc066ab22e 298 Pfam PF01882 Protein of unknown function DUF58 45 130 8.2E-18 T 22-04-2016 IPR002881 Domain of unknown function DUF58 MED134_RS13125 c0e5096abf032ac846752afc066ab22e 298 SUPERFAMILY SSF53300 84 232 9.64E-9 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS13125 c0e5096abf032ac846752afc066ab22e 298 PANTHER PTHR33608:SF2 5 295 6.3E-71 T 22-04-2016 MED134_RS13125 c0e5096abf032ac846752afc066ab22e 298 PANTHER PTHR33608 5 295 6.3E-71 T 22-04-2016 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 SUPERFAMILY SSF52255 1 156 3.4E-63 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 PANTHER PTHR11609:SF5 3 153 1.8E-77 T 22-04-2016 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 SMART SM01001 1 151 1.0E-92 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 157 7.6E-63 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 PIRSF PIRSF001338 1 159 2.2E-67 T 22-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 PANTHER PTHR11609 3 153 1.8E-77 T 22-04-2016 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 Pfam PF00731 AIR carboxylase 2 149 2.9E-64 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 Gene3D G3DSA:3.40.50.7700 1 157 8.0E-70 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS12010 c1e814b7918a37f8dbbc49c7a76260fe 159 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 155 32.238 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PANTHER PTHR11444:SF1 1 461 3.4E-244 T 22-04-2016 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Gene3D G3DSA:1.10.275.10 1 139 3.1E-57 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PANTHER PTHR11444 1 461 3.4E-244 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Gene3D G3DSA:1.10.40.30 406 461 3.7E-29 T 22-04-2016 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 461 6.8E-233 T 22-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 SUPERFAMILY SSF48557 3 461 2.36E-152 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Pfam PF00206 Lyase 11 343 7.5E-110 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Gene3D G3DSA:1.20.200.10 140 404 2.6E-104 T 22-04-2016 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 87.224 T 22-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 4.7E-35 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 4.7E-35 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 4.7E-35 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 4.7E-35 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS00265 09898297bfafcfaf95dfe278e82d2faa 461 Pfam PF10415 Fumarase C C-terminus 409 461 1.1E-22 T 22-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 Gene3D G3DSA:2.30.40.10 31 81 5.8E-9 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 PANTHER PTHR22642:SF1 3 409 4.7E-122 T 22-04-2016 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 SUPERFAMILY SSF51338 3 67 4.32E-13 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 PANTHER PTHR22642 3 409 4.7E-122 T 22-04-2016 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 Gene3D G3DSA:2.30.40.10 354 409 4.3E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 Pfam PF01979 Amidohydrolase family 67 408 3.4E-16 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 TIGRFAM TIGR01224 hutI: imidazolonepropionase 32 408 1.2E-125 T 22-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 Hamap MF_00372 Imidazolonepropionase [hutI]. 1 409 39.491 T 22-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 Gene3D G3DSA:3.20.20.140 82 353 5.7E-37 T 22-04-2016 MED134_RS03160 fc4b8874bb9076732997fd8462cfcc9e 409 SUPERFAMILY SSF51556 72 369 6.81E-71 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 Gene3D G3DSA:3.40.50.620 1 185 9.1E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 SUPERFAMILY SSF52402 1 187 3.98E-33 T 22-04-2016 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 SMART SM00893 3 182 1.5E-9 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 PANTHER PTHR10909 146 310 1.0E-38 T 22-04-2016 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 PANTHER PTHR10909:SF309 146 310 1.0E-38 T 22-04-2016 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 SUPERFAMILY SSF52467 190 312 1.49E-43 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 Pfam PF01012 Electron transfer flavoprotein domain 3 166 2.0E-22 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 PIRSF PIRSF000089 1 317 1.3E-79 T 22-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 Gene3D G3DSA:3.40.50.1220 186 313 2.8E-49 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS07210 e18a7513f4792ae0ca155abd630c82c2 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 193 275 4.2E-30 T 22-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal MED134_RS10105 eab708d52ddea94fa6e0238835bb6722 221 Gene3D G3DSA:3.40.50.2300 3 136 1.2E-11 T 22-04-2016 MED134_RS10105 eab708d52ddea94fa6e0238835bb6722 221 SUPERFAMILY SSF52172 3 143 1.66E-7 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS10105 eab708d52ddea94fa6e0238835bb6722 221 Pfam PF00072 Response regulator receiver domain 5 129 1.6E-5 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS10105 eab708d52ddea94fa6e0238835bb6722 221 Gene3D G3DSA:1.10.10.10 137 220 5.3E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS09620 76ed535f11327408c3678639655d40c7 189 Gene3D G3DSA:1.10.340.30 4 184 4.4E-85 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS09620 76ed535f11327408c3678639655d40c7 189 SUPERFAMILY SSF48150 4 185 1.17E-82 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS09620 76ed535f11327408c3678639655d40c7 189 PANTHER PTHR30037 5 189 8.9E-109 T 22-04-2016 MED134_RS09620 76ed535f11327408c3678639655d40c7 189 Pfam PF03352 Methyladenine glycosylase 8 183 1.1E-82 T 22-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MED134_RS09620 76ed535f11327408c3678639655d40c7 189 PANTHER PTHR30037:SF4 5 189 8.9E-109 T 22-04-2016 MED134_RS09620 76ed535f11327408c3678639655d40c7 189 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 5 184 2.5E-72 T 22-04-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 MED134_RS04835 8ce77413286923d8545ef4809de56672 278 PIRSF PIRSF006779 1 276 1.6E-57 T 22-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase MED134_RS04835 8ce77413286923d8545ef4809de56672 278 SUPERFAMILY SSF101852 165 273 9.29E-13 T 22-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal MED134_RS04835 8ce77413286923d8545ef4809de56672 278 SUPERFAMILY SSF102522 1 151 1.57E-35 T 22-04-2016 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal MED134_RS04835 8ce77413286923d8545ef4809de56672 278 Gene3D G3DSA:2.40.30.90 161 275 6.0E-24 T 22-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal MED134_RS04835 8ce77413286923d8545ef4809de56672 278 PANTHER PTHR35092 1 273 4.0E-34 T 22-04-2016 MED134_RS04835 8ce77413286923d8545ef4809de56672 278 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 271 1.4E-65 T 22-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase MED134_RS07605 7affeb730508ff0c9117fec07b1fa6b3 148 Gene3D G3DSA:1.20.1260.10 4 134 4.6E-10 T 22-04-2016 IPR012347 Ferritin-related MED134_RS07605 7affeb730508ff0c9117fec07b1fa6b3 148 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 9 144 1.1E-27 T 22-04-2016 IPR011971 Conserved hypothetical protein CHP02284 MED134_RS07605 7affeb730508ff0c9117fec07b1fa6b3 148 PIRSF PIRSF029477 1 148 1.9E-33 T 22-04-2016 IPR016920 Uncharacterised conserved protein UCP029477 MED134_RS07605 7affeb730508ff0c9117fec07b1fa6b3 148 Pfam PF09537 Domain of unknown function (DUF2383) 8 115 4.1E-37 T 22-04-2016 IPR019052 Domain of unknown function DUF2383 MED134_RS07605 7affeb730508ff0c9117fec07b1fa6b3 148 SUPERFAMILY SSF47240 6 127 7.39E-11 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 62 78 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 315 331 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 188 202 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 271 295 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 219 245 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 296 314 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PRINTS PR01050 Pyruvate kinase family signature 246 270 6.2E-59 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Gene3D G3DSA:3.40.1380.20 329 475 2.7E-37 T 22-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Gene3D G3DSA:2.40.33.10 76 170 6.8E-29 T 22-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 22-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Pfam PF00224 Pyruvate kinase, barrel domain 5 339 1.2E-116 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Gene3D G3DSA:3.20.20.60 5 75 5.0E-94 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Gene3D G3DSA:3.20.20.60 171 328 5.0E-94 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 Pfam PF02887 Pyruvate kinase, alpha/beta domain 361 472 4.3E-25 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 PANTHER PTHR11817 4 475 1.5E-185 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 SUPERFAMILY SSF52935 327 475 3.66E-30 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 475 3.8E-157 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 SUPERFAMILY SSF51621 158 339 1.46E-92 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 SUPERFAMILY SSF51621 4 77 1.46E-92 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS08930 72d362c79aa2acbfe98b9ef8ab0c094e 475 SUPERFAMILY SSF50800 73 169 2.27E-25 T 22-04-2016 IPR011037 Pyruvate kinase-like, insert domain MED134_RS00595 ec8efa48cc9402ce8c9686cd1189b152 180 SUPERFAMILY SSF111126 1 170 1.15E-37 T 22-04-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain MED134_RS00595 ec8efa48cc9402ce8c9686cd1189b152 180 Pfam PF07700 Haem-NO-binding 2 160 1.3E-37 T 22-04-2016 IPR011644 Heme-NO binding GO:0020037 KEGG: 00230+4.6.1.2 MED134_RS00595 ec8efa48cc9402ce8c9686cd1189b152 180 Gene3D G3DSA:3.90.1520.10 1 178 8.5E-51 T 22-04-2016 MED134_RS08885 de96aa4d6b792d5b06ce4109e1dc1468 139 PANTHER PTHR26402 10 131 2.9E-14 T 22-04-2016 MED134_RS08885 de96aa4d6b792d5b06ce4109e1dc1468 139 SMART SM00448 6 132 6.9E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08885 de96aa4d6b792d5b06ce4109e1dc1468 139 Pfam PF00072 Response regulator receiver domain 9 131 7.2E-15 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08885 de96aa4d6b792d5b06ce4109e1dc1468 139 SUPERFAMILY SSF52172 10 132 1.57E-18 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS08885 de96aa4d6b792d5b06ce4109e1dc1468 139 Gene3D G3DSA:3.40.50.2300 10 133 1.6E-19 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:1.10.8.280 291 409 2.3E-27 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 SUPERFAMILY SSF52540 436 574 9.41E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 7 927 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:1.20.1580.10 696 822 1.5E-54 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 SUPERFAMILY SSF52540 622 913 1.82E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Pfam PF00005 ABC transporter 626 654 5.1E-5 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:1.20.1580.10 95 133 5.4E-49 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:1.20.1580.10 410 482 5.4E-49 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:1.20.1580.10 255 288 5.4E-49 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.30.1490.20 137 157 3.1E-12 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.30.1490.20 204 249 3.1E-12 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 ProSitePatterns PS00211 ABC transporters family signature. 832 846 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 SUPERFAMILY SSF52540 13 208 9.41E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.40.50.300 8 55 1.3E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.40.50.300 607 670 5.2E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.40.50.300 483 599 1.3E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 Gene3D G3DSA:3.40.50.300 823 941 5.2E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 PANTHER PTHR32282:SF2 4 943 0.0 T 22-04-2016 MED134_RS01930 7aef37f1fa6481caafe8ba840372ae84 943 PANTHER PTHR32282 4 943 0.0 T 22-04-2016 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 SUPERFAMILY SSF52402 1 142 7.67E-33 T 22-04-2016 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 PANTHER PTHR31964:SF26 1 151 4.8E-23 T 22-04-2016 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 Gene3D G3DSA:3.40.50.620 148 276 6.8E-20 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 PANTHER PTHR31964 1 151 4.8E-23 T 22-04-2016 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 PRINTS PR01438 Universal stress protein signature 100 112 2.1E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 PRINTS PR01438 Universal stress protein signature 118 140 2.1E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 PRINTS PR01438 Universal stress protein signature 1 19 2.1E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 SUPERFAMILY SSF52402 149 277 8.1E-22 T 22-04-2016 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 Gene3D G3DSA:3.40.50.620 1 142 2.1E-32 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 Pfam PF00582 Universal stress protein family 1 140 3.0E-29 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04670 5c6e2deed060144cf828439151173c0c 278 Pfam PF00582 Universal stress protein family 149 274 4.0E-14 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS06390 fc8bb40db1d543d623df8429425fa796 234 PANTHER PTHR30625 16 233 3.0E-39 T 22-04-2016 MED134_RS06390 fc8bb40db1d543d623df8429425fa796 234 PANTHER PTHR30625:SF0 16 233 3.0E-39 T 22-04-2016 MED134_RS06390 fc8bb40db1d543d623df8429425fa796 234 Pfam PF01618 MotA/TolQ/ExbB proton channel family 98 220 6.4E-30 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 SUPERFAMILY SSF51011 532 636 9.83E-30 T 22-04-2016 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 SUPERFAMILY SSF81296 22 131 3.85E-30 T 22-04-2016 IPR014756 Immunoglobulin E-set MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 6 636 41.78 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Gene3D G3DSA:3.20.20.80 136 509 1.7E-87 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 29 114 6.1E-22 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 537 635 6.0E-20 T 22-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 PANTHER PTHR10357:SF160 9 635 0.0 T 22-04-2016 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 PIRSF PIRSF000463 3 638 6.7E-265 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 SMART SM00642 157 515 2.6E-7 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Pfam PF00128 Alpha amylase, catalytic domain 184 252 1.3E-8 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 14 632 2.0E-257 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 PANTHER PTHR10357 9 635 0.0 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 SUPERFAMILY SSF51445 139 530 5.38E-107 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Gene3D G3DSA:2.60.40.1180 532 635 6.5E-33 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta MED134_RS04465 a0098165f7e85a994aebacc2f936d944 638 Gene3D G3DSA:2.60.40.10 18 128 8.7E-36 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Gene3D G3DSA:3.40.50.970 484 658 1.4E-38 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Gene3D G3DSA:3.40.50.920 659 790 1.8E-26 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 SUPERFAMILY SSF52922 656 790 3.14E-21 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Pfam PF02779 Transketolase, pyrimidine binding domain 471 636 1.4E-19 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 SMART SM00861 468 642 3.0E-22 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 PANTHER PTHR11624:SF21 456 753 3.3E-60 T 22-04-2016 MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 PANTHER PTHR11624:SF21 165 348 3.3E-60 T 22-04-2016 MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Pfam PF00676 Dehydrogenase E1 component 45 355 5.1E-27 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Pfam PF02780 Transketolase, C-terminal domain 658 763 6.0E-19 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 SUPERFAMILY SSF52518 462 647 2.47E-40 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Gene3D G3DSA:3.40.50.970 470 483 1.7E-90 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 Gene3D G3DSA:3.40.50.970 17 374 1.7E-90 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 SUPERFAMILY SSF52518 19 360 4.12E-47 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 PANTHER PTHR11624 456 753 3.3E-60 T 22-04-2016 IPR033247 Transketolase family MED134_RS01945 e02803a7d3be99ac9227bfc76ce47459 802 PANTHER PTHR11624 165 348 3.3E-60 T 22-04-2016 IPR033247 Transketolase family MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 PANTHER PTHR11265:SF0 1 298 6.1E-108 T 22-04-2016 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 Gene3D G3DSA:1.10.150.170 106 208 2.4E-30 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 Gene3D G3DSA:3.40.50.150 4 104 7.5E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 Gene3D G3DSA:3.40.50.150 209 298 7.5E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 SUPERFAMILY SSF81799 108 206 2.09E-29 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 PANTHER PTHR11265 1 298 6.1E-108 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 Pfam PF01795 MraW methylase family 3 297 7.6E-87 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 297 3.0E-88 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 PIRSF PIRSF004486 1 298 8.8E-90 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 298 33.889 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 SUPERFAMILY SSF53335 3 107 2.4E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12495 971cd0ca8ba32e55ac7d81d061a0d92c 298 SUPERFAMILY SSF53335 206 297 2.4E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12925 d0171fa45e5a38f1143dce5a00888bb3 355 Gene3D G3DSA:4.10.1080.10 239 315 3.1E-7 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS12925 d0171fa45e5a38f1143dce5a00888bb3 355 Gene3D G3DSA:4.10.1080.10 316 355 3.6E-5 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS12925 d0171fa45e5a38f1143dce5a00888bb3 355 SUPERFAMILY SSF103647 278 353 1.57E-6 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS12925 d0171fa45e5a38f1143dce5a00888bb3 355 SUPERFAMILY SSF54534 93 162 4.21E-5 T 22-04-2016 MED134_RS12925 d0171fa45e5a38f1143dce5a00888bb3 355 Gene3D G3DSA:3.10.50.40 93 238 7.5E-6 T 22-04-2016 MED134_RS10875 3afaa915d829754b925004b9f486b379 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 2.5E-111 T 22-04-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 MED134_RS10875 3afaa915d829754b925004b9f486b379 250 SUPERFAMILY SSF52540 2 231 2.48E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10875 3afaa915d829754b925004b9f486b379 250 Gene3D G3DSA:3.40.50.300 1 235 2.8E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10875 3afaa915d829754b925004b9f486b379 250 PANTHER PTHR24220:SF85 3 249 4.0E-129 T 22-04-2016 MED134_RS10875 3afaa915d829754b925004b9f486b379 250 Pfam PF00005 ABC transporter 17 172 2.6E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS10875 3afaa915d829754b925004b9f486b379 250 SMART SM00382 26 225 7.6E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS10875 3afaa915d829754b925004b9f486b379 250 PANTHER PTHR24220 3 249 4.0E-129 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SUPERFAMILY SSF52540 194 510 3.7E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:1.10.1780.10 5 146 1.4E-31 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 328 340 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 99 144 1.6E-4 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 64 4.5E-13 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 749 827 3.0E-25 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:1.10.8.60 377 459 4.2E-32 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 695 5.5E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 574 592 5.5E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 5.5E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 5.5E-41 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:1.10.8.60 759 846 1.9E-30 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SUPERFAMILY SSF52540 519 829 1.53E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PANTHER PTHR11638 1 144 0.0 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PANTHER PTHR11638 177 850 0.0 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 604 622 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:3.40.50.300 528 696 1.0E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:3.40.50.300 732 758 1.0E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PANTHER PTHR11638:SF18 1 144 0.0 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 PANTHER PTHR11638:SF18 177 850 0.0 T 22-04-2016 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF02151 UvrB/uvrC motif 450 485 5.8E-5 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF07724 AAA domain (Cdc48 subfamily) 569 742 1.1E-52 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Gene3D G3DSA:3.40.50.300 196 374 1.1E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01975 9a7babf952601b6b86162358935ea918 850 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 238 350 5.6E-12 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SMART SM01086 749 840 2.2E-30 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SUPERFAMILY SSF81923 3 148 3.53E-22 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SMART SM00382 233 377 9.5E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS01975 9a7babf952601b6b86162358935ea918 850 SMART SM00382 570 750 1.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 PANTHER PTHR11935:SF108 1 239 2.1E-26 T 22-04-2016 MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 Gene3D G3DSA:3.60.15.10 23 241 1.9E-44 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 PANTHER PTHR11935 1 239 2.1E-26 T 22-04-2016 MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 Pfam PF00753 Metallo-beta-lactamase superfamily 45 216 2.0E-14 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 SMART SM00849 43 216 1.3E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS11315 9fdd2692c10d8870b1ba5df83fc6a987 295 SUPERFAMILY SSF56281 7 255 6.77E-48 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS05355 751d916827dfaff776f0d5310c645f60 371 Gene3D G3DSA:2.120.10.30 14 368 1.1E-96 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS05355 751d916827dfaff776f0d5310c645f60 371 PANTHER PTHR19328 38 316 5.1E-61 T 22-04-2016 MED134_RS05355 751d916827dfaff776f0d5310c645f60 371 SUPERFAMILY SSF50952 31 367 1.83E-43 T 22-04-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MED134_RS05355 751d916827dfaff776f0d5310c645f60 371 Pfam PF07995 Glucose / Sorbosone dehydrogenase 44 361 3.0E-123 T 22-04-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 SUPERFAMILY SSF109604 313 471 1.18E-28 T 22-04-2016 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 PANTHER PTHR12826 215 520 4.4E-128 T 22-04-2016 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Gene3D G3DSA:3.30.1370.10 221 298 4.8E-6 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 TIGRFAM TIGR00277 HDIG: HDIG domain 333 409 4.9E-21 T 22-04-2016 IPR006675 HDIG domain MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 SUPERFAMILY SSF54791 209 299 8.92E-14 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Pfam PF00013 KH domain 222 254 1.6E-5 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Pfam PF01966 HD domain 338 428 1.1E-17 T 22-04-2016 IPR006674 HD domain MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 SMART SM00322 209 297 1.8E-4 T 22-04-2016 IPR004087 K Homology domain GO:0003676 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Gene3D G3DSA:1.10.3210.10 317 496 1.5E-42 T 22-04-2016 IPR006674 HD domain MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Pfam PF12072 Domain of unknown function (DUF3552) 7 204 1.3E-33 T 22-04-2016 IPR022711 Ribonuclease Y, N-terminal MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 SMART SM00471 333 439 5.2E-11 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 Hamap MF_00335 Ribonuclease Y [rny]. 6 521 22.862 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 MED134_RS11730 3a2c7e3392cfe0036084857e11843b1d 521 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 9 521 3.4E-192 T 22-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 MED134_RS12645 92046adb609b066a66ae8202fafcb248 263 Pfam PF10099 Anti-sigma-K factor rskA 76 251 2.4E-25 T 22-04-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 PANTHER PTHR14359 3 401 2.6E-157 T 22-04-2016 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 SUPERFAMILY SSF102645 188 399 5.36E-67 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 PANTHER PTHR14359:SF20 3 401 2.6E-157 T 22-04-2016 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 397 7.0E-125 T 22-04-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|UniPathway: UPA00241|UniPathway: UPA00241 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 Pfam PF02441 Flavoprotein 7 135 1.3E-32 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 Gene3D G3DSA:3.40.50.10300 191 400 7.8E-75 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 189 372 2.6E-65 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 SUPERFAMILY SSF52507 1 180 1.09E-54 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 MED134_RS05205 caecd0e725e46c4d9ecb5d447fc31f09 401 Gene3D G3DSA:3.40.50.1950 4 190 1.6E-58 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 Pfam PF00270 DEAD/DEAH box helicase 23 197 1.8E-26 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 10 819 0.0 T 22-04-2016 IPR026362 DEXH box helicase, DNA ligase-associated MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031 20 196 2.3E-51 T 22-04-2016 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 SMART SM00490 280 362 3.5E-7 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 SUPERFAMILY SSF52540 230 373 4.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 SUPERFAMILY SSF52540 30 199 4.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 Gene3D G3DSA:3.40.50.300 17 198 2.7E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031:SF122 232 403 2.3E-51 T 22-04-2016 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031:SF122 20 196 2.3E-51 T 22-04-2016 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 SMART SM00487 17 231 1.8E-27 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 Pfam PF08494 DEAD/H associated 604 790 1.0E-48 T 22-04-2016 IPR013701 DEAD/H associated GO:0005524|GO:0016818 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PIRSF PIRSF037307 2 823 2.0E-158 T 22-04-2016 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 Pfam PF00271 Helicase conserved C-terminal domain 255 358 2.3E-13 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031 232 403 2.3E-51 T 22-04-2016 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031 748 823 2.3E-51 T 22-04-2016 MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 Gene3D G3DSA:3.40.50.300 258 393 4.6E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08470 5e2578320b6862d3c9c543f7a94b5758 823 PANTHER PTHR24031:SF122 748 823 2.3E-51 T 22-04-2016 MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 20 301 1.7E-83 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 Pfam PF01715 IPP transferase 52 294 8.4E-73 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 PANTHER PTHR11088 1 304 4.6E-87 T 22-04-2016 MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 SUPERFAMILY SSF52540 19 164 1.33E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 SUPERFAMILY SSF52540 151 224 1.28E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 SUPERFAMILY SSF52540 254 305 1.28E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 SUPERFAMILY SSF52540 19 70 1.28E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 Gene3D G3DSA:1.10.287.890 213 291 3.2E-28 T 22-04-2016 MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 Gene3D G3DSA:3.40.50.300 17 185 3.8E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05160 f7ed53f4d07e43539189097cfcedaeb0 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 19 311 26.843 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 MED134_RS00870 8f46aafaebce909c4649cfa6f0164102 173 Gene3D G3DSA:3.10.180.10 4 157 5.2E-28 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS00870 8f46aafaebce909c4649cfa6f0164102 173 SUPERFAMILY SSF54593 8 159 2.01E-26 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS00870 8f46aafaebce909c4649cfa6f0164102 173 PANTHER PTHR21366:SF16 12 165 9.6E-53 T 22-04-2016 MED134_RS00870 8f46aafaebce909c4649cfa6f0164102 173 PANTHER PTHR21366 12 165 9.6E-53 T 22-04-2016 MED134_RS00870 8f46aafaebce909c4649cfa6f0164102 173 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 154 1.0E-12 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 11 393 8.6E-126 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 PANTHER PTHR30578 3 399 4.1E-152 T 22-04-2016 MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 397 33.649 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 PIRSF PIRSF016055 1 399 5.3E-140 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 PANTHER PTHR30578:SF1 3 399 4.1E-152 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07035 b31e5d3f225a38f47fc268ca2ba6a56e 402 Pfam PF03116 NQR2, RnfD, RnfE family 37 390 3.4E-105 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SMART SM00091 847 915 1.4 T 22-04-2016 IPR000014 PAS domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SMART SM00091 723 791 17.0 T 22-04-2016 IPR000014 PAS domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF13596 PAS domain 725 833 1.2E-23 T 22-04-2016 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF47757 209 276 1.44E-10 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PANTHER PTHR24422 102 844 2.2E-175 T 22-04-2016 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SMART SM00138 208 469 6.4E-77 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF01339 CheB methylesterase 12 187 1.6E-53 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:3.30.565.10 1049 1198 1.3E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:3.30.450.20 725 832 5.0E-7 T 22-04-2016 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:1.10.155.10 209 267 2.4E-11 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PRINTS PR00996 Glutamate methyltransferase family signature 409 423 1.1E-20 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PRINTS PR00996 Glutamate methyltransferase family signature 307 327 1.1E-20 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PRINTS PR00996 Glutamate methyltransferase family signature 343 359 1.1E-20 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PRINTS PR00996 Glutamate methyltransferase family signature 428 451 1.1E-20 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PRINTS PR00996 Glutamate methyltransferase family signature 267 279 1.1E-20 T 22-04-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SMART SM00388 982 1050 2.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SMART SM00387 1090 1200 1.3E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:3.30.450.20 833 946 9.1E-12 T 22-04-2016 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:1.10.287.130 974 1046 4.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:3.40.50.150 273 466 5.4E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF47384 969 1048 5.49E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF55874 1042 1199 2.62E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF52738 7 193 2.48E-52 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF00512 His Kinase A (phospho-acceptor) domain 983 1049 3.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF03705 CheR methyltransferase, all-alpha domain 210 257 4.2E-12 T 22-04-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Gene3D G3DSA:3.40.50.180 5 192 6.9E-61 T 22-04-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF13426 PAS domain 863 959 3.7E-5 T 22-04-2016 IPR000014 PAS domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1093 1199 3.3E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 Pfam PF01739 CheR methyltransferase, SAM binding domain 275 463 4.6E-54 T 22-04-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF53335 274 461 1.56E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 SUPERFAMILY SSF55785 832 959 7.85E-11 T 22-04-2016 IPR000014 PAS domain MED134_RS04870 2d0360472dd281b0cec55fd5d1cc1827 1200 PANTHER PTHR24422:SF6 102 844 2.2E-175 T 22-04-2016 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 PANTHER PTHR11680 4 416 3.1E-233 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 214 230 - T 22-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 PIRSF PIRSF000412 1 419 8.6E-161 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 Gene3D G3DSA:3.40.640.10 29 290 3.3E-97 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 Pfam PF00464 Serine hydroxymethyltransferase 2 392 8.6E-172 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 1 423 50.401 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 Gene3D G3DSA:3.90.1150.10 291 422 3.6E-52 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS00810 dab416120b292329ef66dc055786fb5c 424 SUPERFAMILY SSF53383 2 422 5.9E-170 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 SUPERFAMILY SSF53335 88 396 3.55E-58 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 PANTHER PTHR11061:SF15 14 395 2.4E-78 T 22-04-2016 MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 PANTHER PTHR11061 14 395 2.4E-78 T 22-04-2016 MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 Gene3D G3DSA:3.30.750.80 84 173 3.3E-20 T 22-04-2016 MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 SUPERFAMILY SSF88697 13 77 7.95E-8 T 22-04-2016 IPR015947 PUA-like domain MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 Gene3D G3DSA:3.40.50.150 193 396 6.5E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 Gene3D G3DSA:2.30.130.10 14 78 2.1E-12 T 22-04-2016 IPR015947 PUA-like domain MED134_RS03510 feaa3e50dc4a81ebdad42a41cb0a6f7f 402 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 123 319 2.9E-25 T 22-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 265 328 6.9E-13 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 84 147 7.6E-13 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 840 901 1.5E-8 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 719 791 4.9E-10 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 PANTHER PTHR16026 477 603 3.8E-23 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 PANTHER PTHR16026 370 459 3.8E-23 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 PANTHER PTHR16026 79 341 3.8E-23 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Gene3D G3DSA:2.130.10.130 656 907 2.9E-21 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Gene3D G3DSA:2.130.10.130 919 1071 1.0E-7 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Gene3D G3DSA:2.130.10.130 167 422 1.7E-29 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Gene3D G3DSA:2.130.10.130 458 517 1.7E-29 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SUPERFAMILY SSF69318 622 907 5.75E-52 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SUPERFAMILY SSF69318 456 525 5.75E-52 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 Pfam PF07593 ASPIC and UnbV 538 601 2.9E-15 T 22-04-2016 IPR011519 ASPIC/UnbV MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SUPERFAMILY SSF69318 919 1073 1.44E-11 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SMART SM00191 1015 1077 26.0 T 22-04-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SMART SM00191 655 704 1.3 T 22-04-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SUPERFAMILY SSF69318 66 417 1.7E-65 T 22-04-2016 MED134_RS12170 0a9f367eb5ba16c98d397a093cc4b0dd 1115 SUPERFAMILY SSF69318 452 514 1.7E-65 T 22-04-2016 MED134_RS09490 6f2c710e522c6cdc7cd9c3cdcf104043 311 Pfam PF05036 Sporulation related domain 234 305 7.9E-11 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS09490 6f2c710e522c6cdc7cd9c3cdcf104043 311 Gene3D G3DSA:3.30.70.1070 232 305 3.3E-12 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS09490 6f2c710e522c6cdc7cd9c3cdcf104043 311 SUPERFAMILY SSF110997 233 306 1.96E-15 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 SUPERFAMILY SSF46689 417 466 6.72E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 SMART SM00342 381 466 3.0E-15 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 418 462 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 Gene3D G3DSA:1.10.10.60 417 465 1.3E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 Pfam PF12833 Helix-turn-helix domain 387 467 7.7E-16 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS02610 7b156a1fa917666b9f5086fcc9bf143c 472 PANTHER PTHR11019 365 468 5.6E-16 T 22-04-2016 MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 PANTHER PTHR24220 20 241 7.3E-60 T 22-04-2016 MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 SUPERFAMILY SSF52540 2 240 6.36E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 Pfam PF00005 ABC transporter 20 161 2.8E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 SMART SM00382 26 211 1.9E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS11125 5f17dcb77c7acbbdd521d8605c791109 313 Gene3D G3DSA:3.40.50.300 3 236 3.0E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06425 9d89c102f025514307c850f27492317d 717 Gene3D G3DSA:2.30.42.10 263 351 5.1E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS06425 9d89c102f025514307c850f27492317d 717 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 226 574 3.6E-87 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MED134_RS06425 9d89c102f025514307c850f27492317d 717 Gene3D G3DSA:3.90.226.10 352 556 2.4E-58 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS06425 9d89c102f025514307c850f27492317d 717 Gene3D G3DSA:3.90.226.10 681 702 2.4E-58 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS06425 9d89c102f025514307c850f27492317d 717 PANTHER PTHR32060:SF11 30 626 4.2E-138 T 22-04-2016 MED134_RS06425 9d89c102f025514307c850f27492317d 717 SUPERFAMILY SSF50156 234 357 1.17E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS06425 9d89c102f025514307c850f27492317d 717 SMART SM00228 263 341 1.2E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS06425 9d89c102f025514307c850f27492317d 717 SUPERFAMILY SSF52096 367 558 4.47E-63 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS06425 9d89c102f025514307c850f27492317d 717 SUPERFAMILY SSF52096 217 281 4.47E-63 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS06425 9d89c102f025514307c850f27492317d 717 SMART SM00245 343 554 4.3E-55 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS06425 9d89c102f025514307c850f27492317d 717 Pfam PF03572 Peptidase family S41 373 553 7.0E-48 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS06425 9d89c102f025514307c850f27492317d 717 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 262 337 1.2E-7 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS06425 9d89c102f025514307c850f27492317d 717 PANTHER PTHR32060 30 626 4.2E-138 T 22-04-2016 MED134_RS06425 9d89c102f025514307c850f27492317d 717 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 558 702 1.6E-35 T 22-04-2016 IPR020992 Tail specific protease, C-terminal MED134_RS07750 e91ea1d1989931b6989289f757ea27bc 386 Gene3D G3DSA:2.60.120.10 225 362 6.2E-37 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS07750 e91ea1d1989931b6989289f757ea27bc 386 Gene3D G3DSA:2.60.120.10 92 172 2.1E-8 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS07750 e91ea1d1989931b6989289f757ea27bc 386 PANTHER PTHR11056 8 385 1.5E-74 T 22-04-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 MED134_RS07750 e91ea1d1989931b6989289f757ea27bc 386 Pfam PF04209 homogentisate 1,2-dioxygenase 25 384 1.8E-22 T 22-04-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 MED134_RS07750 e91ea1d1989931b6989289f757ea27bc 386 SUPERFAMILY SSF51182 8 384 5.09E-83 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS00290 077df9b52bb52aa6a5f49fad01097c13 268 Pfam PF12146 Serine aminopeptidase, S33 206 255 1.5E-6 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS00290 077df9b52bb52aa6a5f49fad01097c13 268 Pfam PF12146 Serine aminopeptidase, S33 73 182 2.6E-12 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS00290 077df9b52bb52aa6a5f49fad01097c13 268 SUPERFAMILY SSF53474 25 267 3.02E-39 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00290 077df9b52bb52aa6a5f49fad01097c13 268 Gene3D G3DSA:3.40.50.1820 52 266 5.8E-37 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00290 077df9b52bb52aa6a5f49fad01097c13 268 PANTHER PTHR12277 13 259 5.3E-46 T 22-04-2016 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Gene3D G3DSA:2.40.110.10 123 217 2.4E-39 T 22-04-2016 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 PANTHER PTHR10909 1 379 6.6E-134 T 22-04-2016 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 PANTHER PTHR10909:SF190 1 379 6.6E-134 T 22-04-2016 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 SUPERFAMILY SSF47203 228 383 3.87E-47 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 218 5.0E-24 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 SUPERFAMILY SSF56645 2 241 4.97E-79 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Gene3D G3DSA:1.10.540.10 2 122 1.9E-31 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 2.2E-40 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 9.3E-27 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 Gene3D G3DSA:1.20.140.10 218 383 2.6E-58 T 22-04-2016 MED134_RS04965 606e5772ebf976891b6790a49d78eece 394 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 313 380 0.007 T 22-04-2016 IPR005642 Lysine exporter LysO MED134_RS02590 a40724993a5714dba62a73ad2adbadd6 572 Pfam PF13585 C-terminal domain of CHU protein family 488 555 5.8E-12 T 22-04-2016 MED134_RS02590 a40724993a5714dba62a73ad2adbadd6 572 Gene3D G3DSA:2.60.40.10 237 307 1.8E-4 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS02590 a40724993a5714dba62a73ad2adbadd6 572 SUPERFAMILY SSF49265 136 308 5.24E-9 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS02590 a40724993a5714dba62a73ad2adbadd6 572 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 486 571 5.9E-27 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS02115 32c3aa97c4606e5f6f99eeefd9577bc0 482 Pfam PF14322 Starch-binding associating with outer membrane 23 233 4.8E-24 T 22-04-2016 MED134_RS02115 32c3aa97c4606e5f6f99eeefd9577bc0 482 Pfam PF07980 SusD family 361 482 7.2E-24 T 22-04-2016 IPR012944 RagB/SusD domain MED134_RS02115 32c3aa97c4606e5f6f99eeefd9577bc0 482 SUPERFAMILY SSF48452 18 482 2.6E-87 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02115 32c3aa97c4606e5f6f99eeefd9577bc0 482 Gene3D G3DSA:1.25.40.10 349 428 2.4E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02115 32c3aa97c4606e5f6f99eeefd9577bc0 482 Gene3D G3DSA:1.25.40.10 213 309 2.4E-32 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13605 f829a6ad363a8751faad1a0a07b5f94b 323 Gene3D G3DSA:3.40.630.30 153 301 3.8E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS13605 f829a6ad363a8751faad1a0a07b5f94b 323 Pfam PF13480 Acetyltransferase (GNAT) domain 195 282 1.4E-5 T 22-04-2016 MED134_RS13605 f829a6ad363a8751faad1a0a07b5f94b 323 SUPERFAMILY SSF55729 153 304 6.85E-23 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 SUPERFAMILY SSF53901 216 415 1.27E-71 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 SMART SM00825 Beta-ketoacyl synthase 6 417 1.8E-18 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 1.9E-60 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 Gene3D G3DSA:3.40.47.10 264 415 3.2E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 Gene3D G3DSA:3.40.47.10 4 259 4.6E-75 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 PIRSF PIRSF000447 1 417 9.4E-174 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 369 1.3E-39 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 SUPERFAMILY SSF53901 4 253 4.32E-79 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 413 3.5E-180 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 MED134_RS08950 3861af5cdb0b03e4f70b613b26c975f2 417 PANTHER PTHR11712 4 414 2.8E-202 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 SUPERFAMILY SSF100920 378 534 1.57E-60 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.30.30.30 53 104 3.7E-16 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.30.420.40 4 52 1.2E-61 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.30.420.40 117 189 1.2E-61 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:1.20.1270.10 526 597 2.3E-20 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PANTHER PTHR19375:SF173 2 634 0.0 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 SUPERFAMILY SSF53067 4 182 2.43E-62 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:2.60.34.10 384 525 1.9E-68 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 196 206 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 136 156 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 382 401 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 328 344 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 463 479 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.2E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 190 203 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.90.640.10 224 309 3.3E-29 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.30.420.40 313 355 1.9E-35 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Gene3D G3DSA:3.30.420.40 190 223 1.9E-35 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 597 3.9E-291 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 331 345 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 SUPERFAMILY SSF53067 185 376 6.17E-67 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 633 36.558 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 PANTHER PTHR19375 2 634 0.0 T 22-04-2016 MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 Pfam PF00012 Hsp70 protein 4 597 4.2E-253 T 22-04-2016 IPR013126 Heat shock protein 70 family MED134_RS03905 5b5a06bb18662faed6633c90aae697ff 634 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site MED134_RS12855 ecf23cdd61ace67e79196639226cab74 372 Gene3D G3DSA:2.40.160.50 183 360 1.5E-9 T 22-04-2016 MED134_RS12855 ecf23cdd61ace67e79196639226cab74 372 Pfam PF01103 Surface antigen 56 343 9.6E-12 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 PANTHER PTHR30128 532 651 5.2E-27 T 22-04-2016 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 SUPERFAMILY SSF82171 194 378 9.42E-11 T 22-04-2016 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Gene3D G3DSA:3.30.1330.60 540 651 9.7E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 SUPERFAMILY SSF48452 42 133 3.37E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Gene3D G3DSA:2.130.10.10 221 376 8.3E-8 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 PRINTS PR01021 OMPA domain signature 589 605 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 PRINTS PR01021 OMPA domain signature 544 566 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 PRINTS PR01021 OMPA domain signature 574 589 2.0E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Pfam PF07676 WD40-like Beta Propeller Repeat 336 370 1.3E-4 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 SUPERFAMILY SSF103088 527 650 5.23E-26 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Pfam PF00691 OmpA family 543 631 2.3E-12 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Gene3D G3DSA:1.25.40.10 29 133 3.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Gene3D G3DSA:2.60.40.10 438 507 2.3E-6 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 SUPERFAMILY SSF49478 439 502 2.12E-5 T 22-04-2016 MED134_RS07315 d29fadedbc4b53e26cb3e06c9a2d91a7 653 Pfam PF13620 Carboxypeptidase regulatory-like domain 439 503 2.4E-7 T 22-04-2016 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 SUPERFAMILY SSF116734 181 394 1.14E-38 T 22-04-2016 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 Pfam PF01420 Type I restriction modification DNA specificity domain 230 377 8.0E-14 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 Pfam PF01420 Type I restriction modification DNA specificity domain 5 176 3.8E-26 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 PANTHER PTHR30408:SF2 21 200 4.8E-25 T 22-04-2016 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 PANTHER PTHR30408 21 200 4.8E-25 T 22-04-2016 MED134_RS14615 65eb4e3fb1a2656f4905c9dc2c7c1c5c 395 SUPERFAMILY SSF116734 6 193 1.31E-41 T 22-04-2016 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Pfam PF00270 DEAD/DEAH box helicase 24 188 2.6E-20 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Pfam PF16124 RecQ zinc-binding 342 394 1.4E-6 T 22-04-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Gene3D G3DSA:1.10.150.80 537 611 9.1E-20 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Gene3D G3DSA:3.40.50.300 206 344 2.6E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Pfam PF09382 RQC domain 410 516 4.3E-19 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SUPERFAMILY SSF46785 405 528 1.14E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 12 467 7.8E-146 T 22-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Pfam PF00271 Helicase conserved C-terminal domain 226 331 1.6E-16 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SUPERFAMILY SSF52540 61 350 1.29E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Gene3D G3DSA:3.40.50.300 8 205 1.1E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SMART SM00956 414 517 2.8E-18 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SMART SM00487 17 217 7.8E-34 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Pfam PF00570 HRDC domain 538 604 4.7E-19 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 PANTHER PTHR13710:SF81 1 729 2.6E-227 T 22-04-2016 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SMART SM00490 250 331 4.4E-26 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SMART SM00341 534 614 1.2E-18 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 PANTHER PTHR13710 1 729 2.6E-227 T 22-04-2016 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 SUPERFAMILY SSF47819 531 614 3.27E-24 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MED134_RS04990 d9c0de218a5410e593b0c43eb16b15f3 731 Gene3D G3DSA:1.10.10.10 345 519 1.8E-40 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 SMART SM00490 243 324 4.7E-24 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 Gene3D G3DSA:3.40.50.300 204 335 1.7E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 Pfam PF00270 DEAD/DEAH box helicase 22 178 1.6E-33 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 PANTHER PTHR24031:SF276 9 430 2.0E-124 T 22-04-2016 MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 SMART SM00487 16 207 1.2E-32 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 Pfam PF00271 Helicase conserved C-terminal domain 216 323 5.2E-22 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 SUPERFAMILY SSF52540 65 337 7.34E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 Pfam PF03880 DbpA RNA binding domain 364 434 5.0E-18 T 22-04-2016 IPR005580 DbpA, RNA-binding domain MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 Gene3D G3DSA:3.40.50.300 9 186 1.0E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02200 d629b8b4fea81b867eb82fa9a45f3eab 436 PANTHER PTHR24031 9 430 2.0E-124 T 22-04-2016 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 SUPERFAMILY SSF55874 471 552 1.44E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 PANTHER PTHR24421:SF18 473 554 8.3E-16 T 22-04-2016 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 PANTHER PTHR24421 473 554 8.3E-16 T 22-04-2016 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 Gene3D G3DSA:1.25.40.10 56 265 3.3E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 Pfam PF13176 Tetratricopeptide repeat 123 146 1.2E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 Pfam PF13176 Tetratricopeptide repeat 159 179 0.0091 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 Gene3D G3DSA:3.30.565.10 429 552 1.0E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10100 484973843dd1a5988d7152a11735cfa0 554 SUPERFAMILY SSF48452 103 270 2.12E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 Gene3D G3DSA:3.40.50.620 192 512 7.8E-114 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 SUPERFAMILY SSF52402 206 482 4.75E-74 T 22-04-2016 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 PANTHER PTHR11772 2 540 9.8E-272 T 22-04-2016 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 372 4.5E-117 T 22-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 Pfam PF00733 Asparagine synthase 211 513 4.2E-92 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 Pfam PF13537 Glutamine amidotransferase domain 48 166 1.0E-42 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 PANTHER PTHR11772:SF11 2 540 9.8E-272 T 22-04-2016 MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 SUPERFAMILY SSF56235 1 196 8.58E-59 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS05730 6afc56e915c32c286897d5d35f5c003f 556 Gene3D G3DSA:3.60.20.10 2 191 5.4E-68 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 PANTHER PTHR31760:SF0 2 177 1.4E-52 T 22-04-2016 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 PANTHER PTHR31760 2 177 1.4E-52 T 22-04-2016 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 Pfam PF02527 rRNA small subunit methyltransferase G 15 181 3.1E-37 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 8 203 23.964 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 PIRSF PIRSF003078 2 207 1.3E-49 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 21 180 2.1E-35 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 SUPERFAMILY SSF53335 4 166 5.79E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12430 243d7b023e3bca9375cfa6536f7750b7 209 Gene3D G3DSA:3.40.50.150 3 180 5.9E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 SUPERFAMILY SSF53335 1 283 1.87E-41 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 Gene3D G3DSA:3.40.50.150 1 61 4.7E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 Gene3D G3DSA:3.40.50.150 190 279 4.7E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 5.5E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 3 19 5.5E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 204 216 5.5E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 52 65 5.5E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 207 213 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS09335 565735fb7dc0081c0b35ba370bbe817e 332 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 3 286 9.0E-57 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 SUPERFAMILY SSF53927 9 137 4.07E-35 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 PIRSF PIRSF006019 1 141 3.8E-43 T 22-04-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 69 104 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 115 2.5E-26 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 PANTHER PTHR11086 12 134 8.2E-36 T 22-04-2016 IPR015517 Deoxycytidylate deaminase-related MED134_RS08150 da19e09e1a6befcb6e94d5befd677340 142 Gene3D G3DSA:3.40.140.10 9 137 2.2E-37 T 22-04-2016 MED134_RS14795 6da0700c988db9091b2bbe4e76e4009e 153 Pfam PF07853 Protein of unknown function (DUF1648) 14 58 1.1E-16 T 22-04-2016 IPR012867 Domain of unknown function DUF1648 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 PANTHER PTHR21235 51 235 1.7E-45 T 22-04-2016 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 Pfam PF01884 PcrB family 21 238 6.4E-32 T 22-04-2016 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UniPathway: UPA00940 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 238 3.4E-42 T 22-04-2016 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UniPathway: UPA00940 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 Gene3D G3DSA:3.20.20.390 13 237 9.5E-58 T 22-04-2016 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UniPathway: UPA00940 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 PANTHER PTHR21235:SF22 51 235 1.7E-45 T 22-04-2016 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 SUPERFAMILY SSF51395 19 239 9.52E-30 T 22-04-2016 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 231 2.4E-51 T 22-04-2016 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349|UniPathway: UPA00940 MED134_RS10025 9af61d761db7dc573afb82a6b6c79ebc 241 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 1 241 54.782 T 22-04-2016 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UniPathway: UPA00940 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 SUPERFAMILY SSF51905 5 265 3.56E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 293 3.1E-88 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PANTHER PTHR23023:SF55 4 312 1.0E-60 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 181 9.1E-16 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 289 307 9.1E-16 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 9.1E-16 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 230 9.1E-16 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 9.1E-16 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 Gene3D G3DSA:3.50.50.60 287 302 2.2E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 Gene3D G3DSA:3.50.50.60 7 153 2.2E-23 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 Gene3D G3DSA:3.50.50.60 215 286 9.5E-5 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 Gene3D G3DSA:3.50.50.60 154 214 5.7E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PANTHER PTHR23023 4 312 1.0E-60 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 8 322 6.5E-140 T 22-04-2016 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 1.6E-9 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.6E-9 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 1.6E-9 T 22-04-2016 MED134_RS05475 d7f8a3a6bc416ade2eb038ba15385e99 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.6E-9 T 22-04-2016 MED134_RS01905 e18e38058266b3bd4113211b1b24234c 195 Pfam PF00027 Cyclic nucleotide-binding domain 33 119 1.2E-8 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS01905 e18e38058266b3bd4113211b1b24234c 195 PANTHER PTHR24567:SF33 22 192 5.5E-26 T 22-04-2016 MED134_RS01905 e18e38058266b3bd4113211b1b24234c 195 Gene3D G3DSA:2.60.120.10 6 159 1.8E-33 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS01905 e18e38058266b3bd4113211b1b24234c 195 PANTHER PTHR24567 22 192 5.5E-26 T 22-04-2016 MED134_RS01905 e18e38058266b3bd4113211b1b24234c 195 SUPERFAMILY SSF51206 26 143 5.24E-20 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS14140 c0c8dbdcb1b983ab59a8c182202b383a 259 SMART SM00849 54 222 9.5E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS14140 c0c8dbdcb1b983ab59a8c182202b383a 259 Gene3D G3DSA:3.60.15.10 29 239 2.4E-37 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS14140 c0c8dbdcb1b983ab59a8c182202b383a 259 Pfam PF00753 Metallo-beta-lactamase superfamily 62 222 1.1E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS14140 c0c8dbdcb1b983ab59a8c182202b383a 259 SUPERFAMILY SSF56281 29 228 8.12E-33 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS07645 94ca37444677d37e681fa423d5ad3ac9 95 PANTHER PTHR33606 1 94 2.2E-28 T 22-04-2016 MED134_RS07645 94ca37444677d37e681fa423d5ad3ac9 95 Pfam PF03795 YCII-related domain 1 87 4.0E-13 T 22-04-2016 IPR005545 YCII-related MED134_RS07645 94ca37444677d37e681fa423d5ad3ac9 95 PANTHER PTHR33606:SF3 1 94 2.2E-28 T 22-04-2016 MED134_RS07645 94ca37444677d37e681fa423d5ad3ac9 95 SUPERFAMILY SSF54909 1 89 4.29E-21 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS07645 94ca37444677d37e681fa423d5ad3ac9 95 Gene3D G3DSA:3.30.70.1060 1 89 1.7E-21 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 PANTHER PTHR23389:SF9 1 526 1.2E-175 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:3.40.50.10190 587 662 3.3E-25 T 22-04-2016 IPR001357 BRCT domain MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SMART SM00532 2 442 5.5E-229 T 22-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 401 427 1.2E-8 T 22-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:3.30.470.30 117 245 1.1E-40 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:1.10.150.20 429 497 1.7E-24 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SUPERFAMILY SSF52113 588 661 9.6E-19 T 22-04-2016 IPR001357 BRCT domain MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF12826 Helix-hairpin-helix motif 505 567 3.0E-24 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 587 660 2.4E-15 T 22-04-2016 IPR001357 BRCT domain MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SMART SM00292 588 664 1.7E-11 T 22-04-2016 IPR001357 BRCT domain MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 312 4.2E-115 T 22-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 10 657 2.0E-241 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Hamap MF_01588 DNA ligase [ligA]. 1 662 47.735 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SUPERFAMILY SSF47781 400 577 2.37E-55 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 PANTHER PTHR23389 1 526 1.2E-175 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:2.40.50.140 314 384 2.8E-33 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SUPERFAMILY SSF50249 312 393 5.48E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 325 340 - T 22-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:1.10.150.20 499 578 3.5E-29 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 316 392 5.2E-36 T 22-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SMART SM00278 440 459 160.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SMART SM00278 538 557 4.9 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SMART SM00278 474 493 770.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 PIRSF PIRSF001604 1 664 1.2E-243 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Gene3D G3DSA:1.10.287.610 3 66 2.0E-23 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 Pfam PF14520 Helix-hairpin-helix domain 440 491 0.0057 T 22-04-2016 MED134_RS05245 e41daa6784bd7cafd10d5889acb256f9 664 SUPERFAMILY SSF56091 2 309 2.73E-109 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 4 354 1.2E-181 T 22-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 SUPERFAMILY SSF51735 4 352 5.44E-81 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 Gene3D G3DSA:3.40.50.720 2 191 2.0E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 4 356 55.775 T 22-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 PANTHER PTHR10366 310 357 2.7E-208 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 PANTHER PTHR10366 5 283 2.7E-208 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 PANTHER PTHR10366:SF429 310 357 2.7E-208 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 PANTHER PTHR10366:SF429 5 283 2.7E-208 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 Gene3D G3DSA:3.90.25.10 194 248 7.3E-51 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 Gene3D G3DSA:3.90.25.10 304 362 7.3E-51 T 22-04-2016 MED134_RS09240 4ec1f80c102f78d0ce3a9da492c023de 372 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 346 4.1E-157 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04385 76a8cedf327b32dc61372025f82f9a71 348 SUPERFAMILY SSF51004 34 280 4.71E-6 T 22-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 Gene3D G3DSA:3.40.449.10 22 214 1.3E-74 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 SUPERFAMILY SSF53795 218 534 1.14E-130 T 22-04-2016 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 Pfam PF01293 Phosphoenolpyruvate carboxykinase 22 489 4.4E-217 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 17 536 52.07 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 PANTHER PTHR30031:SF0 1 537 4.3E-280 T 22-04-2016 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 PANTHER PTHR30031 1 537 4.3E-280 T 22-04-2016 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 PIRSF PIRSF006294 5 536 2.3E-223 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 SUPERFAMILY SSF68923 9 214 2.44E-79 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 10 534 9.2E-214 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 Gene3D G3DSA:3.90.228.20 340 534 7.5E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 MED134_RS10190 71b8c26815d583378d9c85707859e09f 537 Gene3D G3DSA:3.90.228.20 218 280 7.5E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 MED134_RS09765 cfb2c562bbfa5f74453f0c01388abf78 376 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 118 290 3.3E-5 T 22-04-2016 IPR007434 Peptidogalycan biosysnthesis/recognition MED134_RS09765 cfb2c562bbfa5f74453f0c01388abf78 376 SUPERFAMILY SSF55729 182 351 2.6E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 133 166 4.4E-12 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 Gene3D G3DSA:2.160.10.10 63 173 1.2E-28 T 22-04-2016 MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 141 169 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 SUPERFAMILY SSF51161 63 174 1.29E-24 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 PANTHER PTHR23416 72 173 4.1E-19 T 22-04-2016 MED134_RS13620 04d39cff06c4a9b38434dd3292f4fc1c 176 PANTHER PTHR23416:SF58 72 173 4.1E-19 T 22-04-2016 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:3.30.1360.120 2 126 7.6E-43 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 222 375 3.3E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:1.20.120.430 392 462 2.9E-54 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:1.20.120.430 127 187 2.9E-54 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:1.20.120.430 253 276 2.9E-54 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 462 2.3E-121 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 224 244 2.2E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 273 288 2.2E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 462 32.483 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 125 3.6E-36 T 22-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 PANTHER PTHR11649 8 462 1.6E-135 T 22-04-2016 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 SUPERFAMILY SSF52540 78 157 2.02E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 SUPERFAMILY SSF52540 193 379 2.02E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Pfam PF01926 50S ribosome-binding GTPase 224 342 4.0E-25 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 SUPERFAMILY SSF116878 126 225 1.31E-47 T 22-04-2016 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 SUPERFAMILY SSF116878 387 462 1.31E-47 T 22-04-2016 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:3.40.50.300 291 390 1.3E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Pfam PF12631 MnmE helical domain 128 459 2.3E-53 T 22-04-2016 IPR025867 MnmE, helical domain MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 PANTHER PTHR11649:SF56 8 462 1.6E-135 T 22-04-2016 MED134_RS01690 27729e921b1660d43cdc15c04d6f14cc 462 Gene3D G3DSA:3.40.50.300 203 252 5.6E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03335 afa3ab060f0ea62a6e8f093c9047a79e 379 Gene3D G3DSA:3.40.710.10 230 378 1.7E-37 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03335 afa3ab060f0ea62a6e8f093c9047a79e 379 Gene3D G3DSA:3.40.710.10 30 164 1.7E-37 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03335 afa3ab060f0ea62a6e8f093c9047a79e 379 Pfam PF13354 Beta-lactamase enzyme family 70 328 5.7E-17 T 22-04-2016 MED134_RS03335 afa3ab060f0ea62a6e8f093c9047a79e 379 SUPERFAMILY SSF56601 219 338 1.33E-20 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03335 afa3ab060f0ea62a6e8f093c9047a79e 379 SUPERFAMILY SSF56601 60 166 1.33E-20 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS07390 f355812415979b91faa284ba4b17b533 446 Gene3D G3DSA:1.20.1600.10 12 438 2.5E-63 T 22-04-2016 MED134_RS07390 f355812415979b91faa284ba4b17b533 446 Pfam PF02321 Outer membrane efflux protein 259 439 3.5E-25 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS07390 f355812415979b91faa284ba4b17b533 446 Pfam PF02321 Outer membrane efflux protein 27 227 2.5E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS07390 f355812415979b91faa284ba4b17b533 446 SUPERFAMILY SSF56954 5 439 1.96E-71 T 22-04-2016 MED134_RS07390 f355812415979b91faa284ba4b17b533 446 PANTHER PTHR30026 1 443 9.2E-41 T 22-04-2016 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00387 550 657 3.7E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 55 175 1.1E-13 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 306 427 4.1E-21 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Pfam PF00989 PAS fold 58 165 5.1E-10 T 22-04-2016 IPR013767 PAS fold GO:0006355 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SUPERFAMILY SSF55874 526 655 8.12E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SUPERFAMILY SSF55785 62 171 5.23E-15 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Gene3D G3DSA:3.30.450.20 58 179 3.3E-17 T 22-04-2016 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00086 126 168 0.02 T 22-04-2016 IPR001610 PAC motif MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00086 381 423 0.0039 T 22-04-2016 IPR001610 PAC motif MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SUPERFAMILY SSF55785 298 421 7.5E-19 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SUPERFAMILY SSF55785 165 295 7.5E-14 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Gene3D G3DSA:1.10.287.130 435 497 2.1E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PANTHER PTHR24423 45 183 4.7E-92 T 22-04-2016 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PANTHER PTHR24423 307 655 4.7E-92 T 22-04-2016 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Pfam PF13426 PAS domain 322 422 6.7E-14 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Pfam PF13426 PAS domain 191 295 1.2E-5 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00388 443 511 6.3E-4 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 616 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 637 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 656 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 602 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SUPERFAMILY SSF47384 432 510 7.85E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Gene3D G3DSA:3.30.565.10 498 656 1.5E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00091 309 376 2.4E-7 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00091 180 253 0.16 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 SMART SM00091 57 121 0.035 T 22-04-2016 IPR000014 PAS domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Gene3D G3DSA:3.30.450.20 180 294 9.3E-15 T 22-04-2016 MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 551 656 1.1E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00600 e63bae9f9cf5f635b324ab93acbdd094 657 Gene3D G3DSA:3.30.450.20 295 421 1.0E-21 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 SUPERFAMILY SSF55979 245 370 8.3E-30 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 368 7.3E-22 T 22-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Gene3D G3DSA:3.10.150.10 248 371 4.3E-33 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 SUPERFAMILY SSF55979 127 243 1.72E-22 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Gene3D G3DSA:3.10.150.10 1 118 2.2E-22 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Gene3D G3DSA:3.10.150.10 126 247 3.2E-29 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 SUPERFAMILY SSF55979 1 117 1.17E-23 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 SMART SM00480 17 363 2.3E-74 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 242 7.6E-22 T 22-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 3.2E-19 T 22-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 PIRSF PIRSF000804 1 371 6.5E-101 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 PANTHER PTHR30478 2 372 7.2E-106 T 22-04-2016 MED134_RS03135 151742344b4f1f1e0eb218c808a9e3bb 372 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 369 1.8E-78 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 PANTHER PTHR10657:SF11 98 372 6.2E-23 T 22-04-2016 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 SUPERFAMILY SSF109998 60 226 4.71E-20 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 SUPERFAMILY SSF54534 208 309 1.44E-20 T 22-04-2016 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 PANTHER PTHR10657 98 372 6.2E-23 T 22-04-2016 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 SUPERFAMILY SSF54534 310 406 1.18E-11 T 22-04-2016 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 Pfam PF00639 PPIC-type PPIASE domain 317 410 1.9E-11 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 Pfam PF00639 PPIC-type PPIASE domain 214 306 1.9E-18 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 Gene3D G3DSA:3.10.50.40 208 310 1.3E-21 T 22-04-2016 MED134_RS00850 5792d7ceda1b10453acbb2fe6edc464e 483 Gene3D G3DSA:3.10.50.40 311 448 2.9E-17 T 22-04-2016 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Pfam PF00072 Response regulator receiver domain 619 728 4.8E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 2.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 2.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 2.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Gene3D G3DSA:3.30.565.10 436 588 1.0E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Gene3D G3DSA:1.25.40.10 33 263 2.7E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SUPERFAMILY SSF52172 616 734 8.54E-35 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SMART SM00387 476 592 5.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 428 1.2E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SMART SM00448 617 728 4.4E-32 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SMART SM00388 364 429 8.4E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Gene3D G3DSA:1.10.287.130 357 425 1.4E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 590 1.8E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SUPERFAMILY SSF55874 418 590 6.16E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PANTHER PTHR24423 257 297 8.1E-125 T 22-04-2016 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PANTHER PTHR24423 25 38 8.1E-125 T 22-04-2016 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 PANTHER PTHR24423 343 739 8.1E-125 T 22-04-2016 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SUPERFAMILY SSF47384 350 430 9.42E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 SUPERFAMILY SSF48452 83 265 3.0E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05880 03cc2caa231acca43a3e95323df9a831 739 Gene3D G3DSA:3.40.50.2300 615 736 1.6E-39 T 22-04-2016 MED134_RS02850 d021120742953f9e6ac55c2c67bfe540 153 Gene3D G3DSA:3.40.30.10 22 131 4.0E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02850 d021120742953f9e6ac55c2c67bfe540 153 SUPERFAMILY SSF52833 29 132 2.16E-5 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 Pfam PF07730 Histidine kinase 72 127 1.7E-5 T 22-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 170 256 1.0E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 SUPERFAMILY SSF55874 148 254 4.45E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 Gene3D G3DSA:3.30.565.10 141 256 7.7E-13 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 PANTHER PTHR24421:SF1 19 255 3.3E-33 T 22-04-2016 MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 SMART SM00387 166 260 2.1E-4 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06880 dffc905b4043dfbb8ba9a07d6b547432 261 PANTHER PTHR24421 19 255 3.3E-33 T 22-04-2016 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 Gene3D G3DSA:2.130.10.120 100 438 1.2E-100 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PANTHER PTHR11757:SF2 1 714 0.0 T 22-04-2016 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PANTHER PTHR11757 1 714 0.0 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 532 551 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 618 633 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 504 528 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 637 659 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 562 582 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 478 496 3.0E-61 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 SUPERFAMILY SSF50993 28 443 6.8E-101 T 22-04-2016 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 SUPERFAMILY SSF53474 446 688 4.28E-50 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 Gene3D G3DSA:3.40.50.1820 446 702 1.1E-48 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 35 434 6.3E-129 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 539 569 - T 22-04-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MED134_RS09870 56d6781de9649cdc46a2bf3aeb8206cf 722 Pfam PF00326 Prolyl oligopeptidase family 493 708 8.2E-68 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 72 303 3.6E-19 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 Gene3D G3DSA:3.40.50.2000 166 335 2.5E-29 T 22-04-2016 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 PANTHER PTHR30160 7 337 3.0E-40 T 22-04-2016 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 PANTHER PTHR30160:SF7 7 337 3.0E-40 T 22-04-2016 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 Gene3D G3DSA:3.40.50.2000 6 148 1.4E-22 T 22-04-2016 MED134_RS09345 549d79495115d07f4ba679dd57945f7f 337 SUPERFAMILY SSF53756 5 335 6.67E-62 T 22-04-2016 MED134_RS11055 c3404abd55a1f43abd7a01a73dec880f 254 Pfam PF13566 Domain of unknown function (DUF4130 83 251 4.7E-50 T 22-04-2016 IPR025404 Domain of unknown function DUF4130 MED134_RS11055 c3404abd55a1f43abd7a01a73dec880f 254 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 5 252 4.8E-86 T 22-04-2016 IPR023875 DNA metabolism protein, putative MED134_RS01925 233001de68f3049f5ecfa9b7e8fd6c44 144 Pfam PF04191 Phospholipid methyltransferase 33 128 3.9E-12 T 22-04-2016 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|UniPathway: UPA00753 MED134_RS01925 233001de68f3049f5ecfa9b7e8fd6c44 144 PANTHER PTHR12714 37 144 2.9E-14 T 22-04-2016 MED134_RS07735 1c02d9ffce6cb312bdc6779a5dedb8f2 312 PANTHER PTHR10138:SF0 7 152 2.1E-25 T 22-04-2016 MED134_RS07735 1c02d9ffce6cb312bdc6779a5dedb8f2 312 PANTHER PTHR10138 7 152 2.1E-25 T 22-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 MED134_RS07735 1c02d9ffce6cb312bdc6779a5dedb8f2 312 Pfam PF03301 Tryptophan 2,3-dioxygenase 40 157 6.1E-24 T 22-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 MED134_RS07735 1c02d9ffce6cb312bdc6779a5dedb8f2 312 SUPERFAMILY SSF140959 41 308 1.83E-76 T 22-04-2016 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 PANTHER PTHR30097:SF3 31 422 4.6E-69 T 22-04-2016 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 Pfam PF11827 Protein of unknown function (DUF3347) 402 573 6.9E-46 T 22-04-2016 IPR021782 Protein of unknown function DUF3347 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 119 326 1.4E-67 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 PANTHER PTHR30097 31 422 4.6E-69 T 22-04-2016 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 113 403 8.1E-42 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 Gene3D G3DSA:2.40.50.100 213 251 1.0E-11 T 22-04-2016 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 Gene3D G3DSA:2.40.50.100 129 165 1.0E-11 T 22-04-2016 MED134_RS00725 590513e522dfdc67d12d7eb130ce1670 577 SUPERFAMILY SSF111369 151 330 1.7E-18 T 22-04-2016 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 Gene3D G3DSA:3.40.50.150 88 287 6.1E-56 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 PANTHER PTHR18895:SF64 7 284 7.2E-74 T 22-04-2016 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 SUPERFAMILY SSF53335 28 284 2.07E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 2 286 1.6E-61 T 22-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 29 284 2.1E-76 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 PANTHER PTHR18895 7 284 7.2E-74 T 22-04-2016 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 Pfam PF05175 Methyltransferase small domain 113 204 1.3E-18 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 MED134_RS05260 b01234afcfc33509232388843e2a5f54 291 Gene3D G3DSA:1.10.8.10 1 87 1.4E-15 T 22-04-2016 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 SUPERFAMILY SSF81338 5 231 3.14E-62 T 22-04-2016 IPR023271 Aquaporin-like MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 Pfam PF00230 Major intrinsic protein 3 226 4.6E-49 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PANTHER PTHR19139 5 233 9.9E-66 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 Gene3D G3DSA:1.20.1080.10 3 232 9.4E-66 T 22-04-2016 IPR023271 Aquaporin-like MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 ProSitePatterns PS00221 MIP family signature. 65 73 - T 22-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 226 7.4E-56 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 47 71 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 171 193 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 210 230 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 84 103 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 141 159 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS05250 c174754dae11bb53ce2bf89cbb9d4a9a 233 PRINTS PR00783 Major intrinsic protein family signature 5 24 5.3E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07780 9778215f20a21075dc3009119b56b9dc 87 Gene3D G3DSA:3.30.40.10 7 60 3.5E-4 T 22-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type MED134_RS07780 9778215f20a21075dc3009119b56b9dc 87 Pfam PF06906 Protein of unknown function (DUF1272) 1 57 1.9E-27 T 22-04-2016 IPR010696 Protein of unknown function DUF1272 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 SMART SM00870 5 328 2.0E-111 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PANTHER PTHR11707:SF28 3 340 3.1E-128 T 22-04-2016 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 SUPERFAMILY SSF53774 4 340 4.06E-104 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PIRSF PIRSF500176 2 337 1.3E-96 T 22-04-2016 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PANTHER PTHR11707 3 340 3.1E-128 T 22-04-2016 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 Gene3D G3DSA:3.40.50.40 214 340 9.2E-47 T 22-04-2016 IPR027473 L-asparaginase, C-terminal domain MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 Gene3D G3DSA:3.40.50.1170 2 212 1.5E-69 T 22-04-2016 IPR027474 L-asparaginase, N-terminal MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PIRSF PIRSF001220 1 339 2.1E-92 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 Pfam PF00710 Asparaginase, N-terminal 5 196 1.6E-61 T 22-04-2016 IPR027474 L-asparaginase, N-terminal MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 4 339 3.6E-94 T 22-04-2016 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 1.0E-14 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PRINTS PR00139 Asparaginase/glutaminase family signature 265 283 1.0E-14 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 1.0E-14 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 MED134_RS05960 a633acbf589ad720456d0c00df0d36f8 340 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 22-04-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MED134_RS14155 3b2edcf69558015d6999428825cdeef3 186 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 185 1.4E-42 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 MED134_RS14155 3b2edcf69558015d6999428825cdeef3 186 PANTHER PTHR17490 6 185 1.7E-41 T 22-04-2016 MED134_RS14155 3b2edcf69558015d6999428825cdeef3 186 SUPERFAMILY SSF55821 6 185 6.41E-41 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS14155 3b2edcf69558015d6999428825cdeef3 186 Gene3D G3DSA:3.90.870.10 3 186 3.4E-50 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS14155 3b2edcf69558015d6999428825cdeef3 186 Pfam PF01300 Telomere recombination 11 186 2.4E-41 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 MED134_RS13770 f3b60b6982908e520407c38d163ef37c 277 PANTHER PTHR37296 1 277 1.0E-85 T 22-04-2016 MED134_RS13770 f3b60b6982908e520407c38d163ef37c 277 Pfam PF13509 S1 domain 79 129 8.5E-5 T 22-04-2016 MED134_RS13770 f3b60b6982908e520407c38d163ef37c 277 Pfam PF13509 S1 domain 4 63 5.1E-21 T 22-04-2016 MED134_RS13770 f3b60b6982908e520407c38d163ef37c 277 PIRSF PIRSF012524 1 277 3.2E-71 T 22-04-2016 IPR014464 Conserved virulence factor B MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 Pfam PF00691 OmpA family 566 656 1.1E-17 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 PANTHER PTHR30128 536 674 2.5E-32 T 22-04-2016 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 Gene3D G3DSA:3.30.1330.60 552 672 1.6E-34 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 Gene3D G3DSA:1.25.40.10 18 129 1.6E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 Gene3D G3DSA:2.120.10.30 279 429 1.2E-5 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 SUPERFAMILY SSF103088 554 671 9.55E-30 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 Pfam PF07676 WD40-like Beta Propeller Repeat 284 315 8.2E-6 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 PRINTS PR01021 OMPA domain signature 597 612 2.6E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 PRINTS PR01021 OMPA domain signature 612 628 2.6E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 PRINTS PR01021 OMPA domain signature 567 589 2.6E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 SUPERFAMILY SSF82171 256 371 4.84E-9 T 22-04-2016 MED134_RS03890 d2b3bf5c2c5d9a60ebad154195d2d618 674 SUPERFAMILY SSF48452 14 122 1.01E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 Gene3D G3DSA:3.30.565.10 216 382 3.8E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 83 153 1.7E-6 T 22-04-2016 IPR000014 PAS domain MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 SMART SM00387 275 383 1.7E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 PANTHER PTHR24423:SF518 99 383 5.6E-41 T 22-04-2016 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 383 1.3E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 328 1.3E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 1.3E-7 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 SMART SM00086 104 146 8.4E-8 T 22-04-2016 IPR001610 PAC motif MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 Pfam PF08447 PAS fold 70 139 1.8E-7 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 279 382 8.7E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 Gene3D G3DSA:3.30.450.20 34 143 8.5E-13 T 22-04-2016 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 SUPERFAMILY SSF55785 46 155 1.69E-11 T 22-04-2016 IPR000014 PAS domain MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 PANTHER PTHR24423 99 383 5.6E-41 T 22-04-2016 MED134_RS08890 babb6ef91286c0d6d12f045341764ea4 383 SUPERFAMILY SSF55874 233 382 1.7E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 SUPERFAMILY SSF55781 28 171 4.32E-21 T 22-04-2016 IPR029016 GAF domain-like MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 Gene3D G3DSA:3.30.565.10 235 398 1.3E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 Pfam PF01590 GAF domain 41 156 3.2E-6 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 7.6E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 7.6E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 7.6E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 Gene3D G3DSA:3.30.450.40 24 157 3.8E-8 T 22-04-2016 IPR029016 GAF domain-like MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 SMART SM00388 181 247 5.8E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 SMART SM00387 289 401 1.6E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 SUPERFAMILY SSF55874 259 398 2.62E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 SUPERFAMILY SSF47384 166 243 1.2E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 Gene3D G3DSA:1.10.287.130 175 234 3.7E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 PANTHER PTHR24423 160 398 1.8E-47 T 22-04-2016 MED134_RS01160 52b670fdf56be3216326177c8cb553f1 401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 398 3.5E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 95 20.109 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 SUPERFAMILY SSF46911 27 95 6.54E-26 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 TIGRFAM TIGR00165 S18: ribosomal protein bS18 28 95 1.7E-29 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 PRINTS PR00974 Ribosomal protein S18 family signature 50 60 4.8E-17 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 PRINTS PR00974 Ribosomal protein S18 family signature 82 92 4.8E-17 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 PRINTS PR00974 Ribosomal protein S18 family signature 60 67 4.8E-17 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 PRINTS PR00974 Ribosomal protein S18 family signature 68 82 4.8E-17 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 Pfam PF01084 Ribosomal protein S18 40 90 1.4E-21 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 PANTHER PTHR13479 29 94 4.2E-25 T 22-04-2016 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 42 93 7.0E-18 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02215 df4566e54cf479c9b34cd5cabefc0b8a 98 Gene3D G3DSA:4.10.640.10 30 95 6.0E-30 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 SUPERFAMILY SSF54826 3 137 2.21E-57 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 ProSitePatterns PS00164 Enolase signature. 337 350 - T 22-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 426 4.8E-127 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 Gene3D G3DSA:3.20.20.120 127 427 9.0E-134 T 22-04-2016 IPR029065 Enolase C-terminal domain-like MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PANTHER PTHR11902 1 420 1.3E-259 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PIRSF PIRSF001400 1 428 2.8E-191 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 SMART SM01193 4 133 4.0E-98 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 SUPERFAMILY SSF51604 138 426 3.11E-125 T 22-04-2016 IPR029065 Enolase C-terminal domain-like MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 160 173 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 314 325 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 106 122 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 37 51 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 337 351 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 PRINTS PR00148 Enolase signature 366 383 1.2E-46 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 Pfam PF03952 Enolase, N-terminal domain 4 133 1.8E-61 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 7.4E-203 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 Hamap MF_00318 Enolase [eno]. 2 414 44.183 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 Gene3D G3DSA:3.30.390.10 4 125 3.2E-58 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MED134_RS12380 540950bfef9a67f28fbeebd91eafe3f0 429 SMART SM01192 138 428 1.7E-209 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 331 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 345 2.4E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SMART SM00387 279 390 2.4E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 PANTHER PTHR24423 152 390 3.2E-52 T 22-04-2016 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SMART SM00065 19 161 3.5E-9 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Gene3D G3DSA:3.30.450.40 20 166 1.6E-13 T 22-04-2016 IPR029016 GAF domain-like MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Pfam PF01590 GAF domain 21 147 5.0E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SUPERFAMILY SSF47384 159 239 8.24E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SUPERFAMILY SSF55874 249 388 4.19E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SUPERFAMILY SSF55781 20 163 2.7E-22 T 22-04-2016 IPR029016 GAF domain-like MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Gene3D G3DSA:1.10.287.130 167 226 3.9E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Pfam PF00512 His Kinase A (phospho-acceptor) domain 174 240 8.2E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Gene3D G3DSA:3.30.565.10 227 389 7.6E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 388 4.5E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02020 791236680d6ccae6186e079e4394b46a 390 SMART SM00388 173 241 1.1E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 59 8.4E-21 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 8.4E-21 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 149 8.4E-21 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 82 94 8.4E-21 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 SUPERFAMILY SSF50891 31 209 8.91E-51 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 Gene3D G3DSA:3.10.50.40 237 389 5.9E-35 T 22-04-2016 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 279 386 1.8E-22 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 31 207 1.6E-41 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 Gene3D G3DSA:2.40.100.10 17 211 1.1E-55 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PANTHER PTHR11071 35 150 1.2E-57 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 PANTHER PTHR11071 167 209 1.2E-57 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 SUPERFAMILY SSF54534 223 389 2.16E-31 T 22-04-2016 MED134_RS13565 1a5f8426930dfbdd7e599bb18b53ecb0 390 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 77 94 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MED134_RS07495 ef251df79c7049bbd11e80750ff84045 423 PANTHER PTHR35093:SF2 1 423 8.7E-58 T 22-04-2016 MED134_RS07495 ef251df79c7049bbd11e80750ff84045 423 SUPERFAMILY SSF56935 21 423 4.76E-62 T 22-04-2016 MED134_RS07495 ef251df79c7049bbd11e80750ff84045 423 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 11 419 3.4E-54 T 22-04-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MED134_RS07495 ef251df79c7049bbd11e80750ff84045 423 Gene3D G3DSA:2.40.160.60 21 422 5.8E-89 T 22-04-2016 MED134_RS07495 ef251df79c7049bbd11e80750ff84045 423 PANTHER PTHR35093 1 423 8.7E-58 T 22-04-2016 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 Pfam PF04023 FeoA domain 146 215 2.1E-9 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 SUPERFAMILY SSF47979 64 137 5.76E-27 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 PANTHER PTHR33238 1 215 5.0E-65 T 22-04-2016 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 SUPERFAMILY SSF46785 3 63 4.34E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 SMART SM00899 144 217 1.5E-4 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 Gene3D G3DSA:1.10.60.10 74 138 2.7E-30 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 133 3.0E-30 T 22-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 60 2.4E-17 T 22-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 Gene3D G3DSA:1.10.10.10 2 72 4.3E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 SMART SM00529 25 124 2.4E-40 T 22-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MED134_RS10260 d1087a190bf1e0f2ee592157bed560df 217 PANTHER PTHR33238:SF1 1 215 5.0E-65 T 22-04-2016 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 PIRSF PIRSF000077 1 105 3.9E-42 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 1.6E-38 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 SUPERFAMILY SSF52833 3 105 4.59E-41 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 Gene3D G3DSA:3.40.30.10 3 103 1.3E-38 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 PANTHER PTHR10438 1 105 8.6E-41 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 PRINTS PR00421 Thioredoxin family signature 69 80 8.2E-9 T 22-04-2016 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 PRINTS PR00421 Thioredoxin family signature 29 38 8.2E-9 T 22-04-2016 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 PRINTS PR00421 Thioredoxin family signature 21 29 8.2E-9 T 22-04-2016 MED134_RS10125 fe5c0e39c7ddd3734b454125db3a5787 105 Pfam PF00085 Thioredoxin 4 101 9.1E-32 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 SUPERFAMILY SSF48179 348 485 3.23E-42 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Gene3D G3DSA:3.40.50.720 1 201 5.1E-71 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 9.0E-123 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 354 482 1.5E-19 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 343 3.1E-30 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 PANTHER PTHR21371 1 495 8.2E-186 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Gene3D G3DSA:1.10.1040.10 330 482 5.0E-18 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 2.2E-58 T 22-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 22 486 36.316 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 SUPERFAMILY SSF51735 27 209 7.67E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04725 39a39da7b29e5a0a9ce705b1d8c98a67 498 SUPERFAMILY SSF48179 210 371 1.56E-43 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 Pfam PF00924 Mechanosensitive ion channel 70 272 5.7E-42 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 PANTHER PTHR30221 1 276 9.7E-47 T 22-04-2016 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 Gene3D G3DSA:2.30.30.60 130 179 5.9E-17 T 22-04-2016 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 SUPERFAMILY SSF50182 116 180 1.54E-16 T 22-04-2016 IPR010920 LSM domain MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 PANTHER PTHR30221:SF7 1 276 9.7E-47 T 22-04-2016 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 Gene3D G3DSA:3.30.70.100 184 272 4.0E-16 T 22-04-2016 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 SUPERFAMILY SSF82861 27 113 2.35E-9 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS02840 84d84f2efad74ac42144a3bd3e2b1066 300 SUPERFAMILY SSF82689 182 285 7.45E-16 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MED134_RS04455 835f6c535801d2edfe049d7245a1192e 273 Gene3D G3DSA:3.30.2010.10 81 151 1.4E-11 T 22-04-2016 MED134_RS04455 835f6c535801d2edfe049d7245a1192e 273 Pfam PF01435 Peptidase family M48 91 255 1.2E-32 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MED134_RS04455 835f6c535801d2edfe049d7245a1192e 273 PANTHER PTHR22726 23 258 8.3E-58 T 22-04-2016 MED134_RS04150 f79d7921cc0274c838ec9a1597894fda 487 PANTHER PTHR33451:SF3 3 487 1.0E-140 T 22-04-2016 MED134_RS04150 f79d7921cc0274c838ec9a1597894fda 487 PANTHER PTHR33451 3 487 1.0E-140 T 22-04-2016 MED134_RS04150 f79d7921cc0274c838ec9a1597894fda 487 Pfam PF03553 Na+/H+ antiporter family 177 474 2.3E-43 T 22-04-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Gene3D G3DSA:3.40.50.300 61 248 8.9E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Gene3D G3DSA:3.40.50.300 286 303 8.9E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Pfam PF07724 AAA domain (Cdc48 subfamily) 106 302 1.8E-45 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 PANTHER PTHR11262:SF4 3 397 7.3E-192 T 22-04-2016 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Pfam PF06689 ClpX C4-type zinc finger 7 41 3.4E-14 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 SMART SM00994 5 44 5.5E-16 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 406 45.668 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 SUPERFAMILY SSF57716 6 41 1.14E-8 T 22-04-2016 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Gene3D G3DSA:1.10.8.60 309 404 1.5E-29 T 22-04-2016 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 110 123 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 309 384 3.4E-14 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 PANTHER PTHR11262 3 397 7.3E-192 T 22-04-2016 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 3 393 1.1E-168 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 SMART SM00382 106 263 5.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 SMART SM01086 309 403 1.8E-26 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS07470 9c37f8303f2d8a7843b798be05ef1c9d 410 SUPERFAMILY SSF52540 60 395 2.4E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 Gene3D G3DSA:3.40.50.1980 24 236 4.4E-75 T 22-04-2016 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PANTHER PTHR21256:SF2 8 427 2.3E-212 T 22-04-2016 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PIRSF PIRSF000099 1 426 2.2E-164 T 22-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 SUPERFAMILY SSF53720 10 424 5.69E-85 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 423 38.861 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 166 192 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 196 221 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 248 267 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 316 341 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 131 157 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 226 247 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 30 54 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PRINTS PR00083 Histidinol dehydrogenase signature 357 375 3.9E-87 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 226 258 - T 22-04-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 PANTHER PTHR21256 8 427 2.3E-212 T 22-04-2016 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 Pfam PF00815 Histidinol dehydrogenase 17 423 8.8E-168 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS02445 08dd306acd457aee24e198a3bffde10e 427 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 30 422 4.4E-158 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Gene3D G3DSA:1.10.3850.10 815 1031 1.4E-50 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 SUPERFAMILY SSF82714 182 262 3.53E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PANTHER PTHR32063:SF33 1 1078 1.3E-258 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 SUPERFAMILY SSF82714 732 808 5.1E-13 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 SUPERFAMILY SSF82866 290 483 5.1E-35 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Gene3D G3DSA:3.30.2090.10 732 806 2.5E-11 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 SUPERFAMILY SSF82866 810 1031 7.06E-43 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Gene3D G3DSA:3.30.2090.10 180 265 2.5E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 3.5E-20 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PRINTS PR00702 Acriflavin resistance protein family signature 381 405 3.5E-20 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.5E-20 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PRINTS PR00702 Acriflavin resistance protein family signature 353 374 3.5E-20 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Pfam PF00873 AcrB/AcrD/AcrF family 5 1028 9.4E-161 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Gene3D G3DSA:1.20.1640.10 286 495 4.5E-41 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 Gene3D G3DSA:3.30.70.1430 42 133 2.4E-24 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 SUPERFAMILY SSF82693 42 131 6.98E-22 T 22-04-2016 MED134_RS06060 6f28dc103c05f168bb82bf8da6d45a0b 1082 PANTHER PTHR32063 1 1078 1.3E-258 T 22-04-2016 MED134_RS05845 ffa2c5c1ff04ab1f91f36718f8873a9e 267 PANTHER PTHR13773:SF0 1 262 1.4E-45 T 22-04-2016 MED134_RS05845 ffa2c5c1ff04ab1f91f36718f8873a9e 267 PANTHER PTHR13773 1 262 1.4E-45 T 22-04-2016 MED134_RS05845 ffa2c5c1ff04ab1f91f36718f8873a9e 267 Pfam PF01148 Cytidylyltransferase family 6 260 7.0E-54 T 22-04-2016 MED134_RS10420 33928f34d1c935d700ad2116b0c43ef2 144 Pfam PF14534 Domain of unknown function (DUF4440) 30 138 2.2E-7 T 22-04-2016 IPR027843 Domain of unknown function DUF4440 MED134_RS10420 33928f34d1c935d700ad2116b0c43ef2 144 Gene3D G3DSA:3.10.450.50 25 144 3.8E-46 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS10420 33928f34d1c935d700ad2116b0c43ef2 144 SUPERFAMILY SSF54427 26 144 4.65E-28 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 PIRSF PIRSF001109 1 438 1.3E-196 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 219 236 - T 22-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 SUPERFAMILY SSF51735 197 358 2.14E-70 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 PANTHER PTHR23420 4 438 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Gene3D G3DSA:3.40.50.1480 10 234 2.8E-122 T 22-04-2016 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 6 430 47.536 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 SMART SM00997 197 358 2.7E-107 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Gene3D G3DSA:3.40.50.720 235 311 1.0E-11 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 82 96 - T 22-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 11 430 2.8E-194 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 SUPERFAMILY SSF52283 8 196 2.27E-118 T 22-04-2016 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 SUPERFAMILY SSF52283 359 438 2.27E-118 T 22-04-2016 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Gene3D G3DSA:3.40.50.1480 359 438 4.9E-36 T 22-04-2016 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 11 147 6.0E-71 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 148 437 4.3E-62 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 SMART SM00996 10 437 0.0 T 22-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS10155 0b9b74af5485d136f0d8149fb723ad7d 438 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 197 358 2.2E-78 T 22-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 MED134_RS01100 3b75ce70fd458e3a61cac9d9b407437b 160 Gene3D G3DSA:3.10.450.50 2 119 2.9E-21 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS01100 3b75ce70fd458e3a61cac9d9b407437b 160 Pfam PF12680 SnoaL-like domain 5 106 1.1E-14 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain MED134_RS01100 3b75ce70fd458e3a61cac9d9b407437b 160 SUPERFAMILY SSF54427 3 129 1.29E-26 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 PANTHER PTHR37838:SF1 1 234 1.0E-38 T 22-04-2016 MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 5 248 25.909 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 Pfam PF04205 FMN-binding domain 136 234 3.6E-13 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 5 240 1.1E-48 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 SMART SM00900 136 237 1.3E-15 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 MED134_RS07030 bf198d5b57ef33fffd844012cbf695a3 248 PANTHER PTHR37838 1 234 1.0E-38 T 22-04-2016 MED134_RS10480 4e6790b2ddd96fa5c73df5135b52fb41 302 Pfam PF08787 Alginate lyase 54 302 7.4E-51 T 22-04-2016 IPR014895 Alginate lyase 2 MED134_RS10480 4e6790b2ddd96fa5c73df5135b52fb41 302 Gene3D G3DSA:2.60.120.200 46 302 3.6E-57 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS10480 4e6790b2ddd96fa5c73df5135b52fb41 302 SUPERFAMILY SSF49899 54 302 1.9E-29 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Gene3D G3DSA:1.10.1780.10 1 146 2.2E-40 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SUPERFAMILY SSF52540 543 858 1.49E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Gene3D G3DSA:1.10.8.60 778 860 1.6E-28 T 22-04-2016 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SMART SM01086 768 857 2.3E-33 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 846 1.7E-23 T 22-04-2016 IPR019489 Clp ATPase, C-terminal MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Gene3D G3DSA:1.10.8.60 342 426 2.3E-36 T 22-04-2016 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 142 3.4E-10 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 9.4E-8 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SMART SM00382 196 341 6.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SMART SM00382 594 747 1.9E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 22-04-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 292 304 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Pfam PF07724 AAA domain (Cdc48 subfamily) 593 762 2.0E-51 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 1.5E-13 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Gene3D G3DSA:3.40.50.300 157 340 5.7E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SUPERFAMILY SSF52540 156 542 6.23E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 705 719 2.8E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 616 2.8E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 672 690 2.8E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 643 661 2.8E-39 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PANTHER PTHR11638:SF18 1 868 0.0 T 22-04-2016 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 628 646 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 PANTHER PTHR11638 1 868 0.0 T 22-04-2016 MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 Gene3D G3DSA:3.40.50.300 547 777 1.1E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02150 be6fa5881e4c1f35ef566282d62ef406 868 SUPERFAMILY SSF81923 4 154 3.34E-40 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 MED134_RS06395 5c8e5b2ab9765e182e0e1ee0c2db731c 467 PANTHER PTHR10283 2 57 5.0E-125 T 22-04-2016 MED134_RS06395 5c8e5b2ab9765e182e0e1ee0c2db731c 467 PANTHER PTHR10283 87 458 5.0E-125 T 22-04-2016 MED134_RS06395 5c8e5b2ab9765e182e0e1ee0c2db731c 467 PANTHER PTHR10283:SF103 2 57 5.0E-125 T 22-04-2016 MED134_RS06395 5c8e5b2ab9765e182e0e1ee0c2db731c 467 PANTHER PTHR10283:SF103 87 458 5.0E-125 T 22-04-2016 MED134_RS06395 5c8e5b2ab9765e182e0e1ee0c2db731c 467 Pfam PF03600 Citrate transporter 24 396 1.6E-28 T 22-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 MED134_RS01750 98389af6e6d6301b3bda1ee4d93b216d 371 Pfam PF05139 Erythromycin esterase 67 362 3.2E-13 T 22-04-2016 IPR007815 Erythromycin esterase GO:0046677 MED134_RS01750 98389af6e6d6301b3bda1ee4d93b216d 371 Gene3D G3DSA:3.40.1660.10 6 68 3.7E-18 T 22-04-2016 MED134_RS01750 98389af6e6d6301b3bda1ee4d93b216d 371 Gene3D G3DSA:3.40.1660.10 245 363 3.7E-18 T 22-04-2016 MED134_RS01750 98389af6e6d6301b3bda1ee4d93b216d 371 SUPERFAMILY SSF159501 2 363 1.78E-51 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SUPERFAMILY SSF50249 43 196 9.3E-42 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.30.56.10 1 38 2.9E-22 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.30.56.10 163 189 2.9E-22 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SMART SM00873 226 399 4.4E-88 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:2.40.50.140 45 159 6.2E-41 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SMART SM00896 715 808 1.1E-41 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.30.930.10 507 703 2.0E-43 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.50.40.10 215 409 9.2E-84 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Pfam PF03484 tRNA synthetase B5 domain 420 485 1.4E-15 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Pfam PF01588 Putative tRNA binding domain 48 152 1.8E-23 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SUPERFAMILY SSF55681 481 702 1.09E-28 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SUPERFAMILY SSF46955 418 488 6.04E-14 T 22-04-2016 IPR009061 Putative DNA-binding domain MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SUPERFAMILY SSF56037 216 410 1.02E-70 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SUPERFAMILY SSF54991 710 808 3.53E-30 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.30.56.20 416 488 6.5E-20 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 PANTHER PTHR10947:SF0 2 808 1.5E-256 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 PANTHER PTHR10947 2 808 1.5E-256 T 22-04-2016 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 808 9.9E-256 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 SMART SM00874 416 485 6.9E-17 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Gene3D G3DSA:3.30.70.380 717 808 1.3E-30 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Pfam PF03147 Ferredoxin-fold anticodon binding domain 715 808 1.1E-29 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 802 40.755 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS03075 f2ff53cd9c42956277ee2d5188513210 808 Pfam PF03483 B3/4 domain 227 399 8.8E-68 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MED134_RS10340 7097025afd8e2b438d7430b50ee63392 533 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 460 530 2.2E-8 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 MED134_RS10340 7097025afd8e2b438d7430b50ee63392 533 SUPERFAMILY SSF74653 470 529 2.88E-8 T 22-04-2016 MED134_RS10340 7097025afd8e2b438d7430b50ee63392 533 Pfam PF05569 BlaR1 peptidase M56 143 252 7.5E-13 T 22-04-2016 IPR008756 Peptidase M56 MED134_RS01015 b8209713ed965bd1fc9e807b16f56e5f 201 Pfam PF13568 Outer membrane protein beta-barrel domain 25 168 1.1E-15 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS10380 87e983af001a1c51e7b4436c9be6709b 252 SUPERFAMILY SSF102198 18 232 2.09E-13 T 22-04-2016 MED134_RS10380 87e983af001a1c51e7b4436c9be6709b 252 Pfam PF04199 Putative cyclase 20 185 1.1E-12 T 22-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 MED134_RS10380 87e983af001a1c51e7b4436c9be6709b 252 Gene3D G3DSA:3.50.30.50 18 245 8.7E-15 T 22-04-2016 MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 111 7.9E-34 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 SUPERFAMILY SSF81301 8 120 9.65E-36 T 22-04-2016 MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 Gene3D G3DSA:3.30.460.10 8 114 2.6E-33 T 22-04-2016 MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 PANTHER PTHR21043 1 123 6.7E-31 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 8 112 22.448 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MED134_RS05860 7d321e659bf59395f3f1fd6e735d371e 123 Pfam PF02410 Ribosomal silencing factor during starvation 14 111 8.5E-26 T 22-04-2016 MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 PANTHER PTHR10314 18 289 1.0E-39 T 22-04-2016 MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 281 4.7E-18 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 Gene3D G3DSA:3.40.50.1100 94 295 7.8E-59 T 22-04-2016 MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 PIRSF PIRSF006278 5 297 1.8E-72 T 22-04-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 PANTHER PTHR10314:SF79 18 289 1.0E-39 T 22-04-2016 MED134_RS11590 ef7f268f0248a28e0d1e7ea2e4b0d03f 302 SUPERFAMILY SSF53686 14 291 1.05E-54 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 Gene3D G3DSA:2.20.110.10 5 109 1.7E-13 T 22-04-2016 MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 Pfam PF07661 MORN repeat variant 46 67 0.052 T 22-04-2016 IPR011652 MORN variant MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 Pfam PF07661 MORN repeat variant 22 43 0.0014 T 22-04-2016 IPR011652 MORN variant MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 SUPERFAMILY SSF82185 38 122 3.79E-14 T 22-04-2016 MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 PANTHER PTHR33706:SF1 6 124 8.4E-15 T 22-04-2016 MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 PANTHER PTHR33706 6 124 8.4E-15 T 22-04-2016 MED134_RS10555 493a6229674dbdddf65bdd2068b25f31 140 SUPERFAMILY SSF82185 4 48 1.57E-7 T 22-04-2016 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 SUPERFAMILY SSF56935 29 725 3.66E-85 T 22-04-2016 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 Gene3D G3DSA:2.170.130.10 44 153 7.2E-12 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 Gene3D G3DSA:2.40.170.20 154 725 2.7E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 PANTHER PTHR32552 1 725 2.1E-93 T 22-04-2016 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 152 7.4E-9 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10015 b6df1a42d084c7c7bae3b0a620d3879d 725 PANTHER PTHR32552:SF38 1 725 2.1E-93 T 22-04-2016 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 PANTHER PTHR30173:SF21 5 173 5.6E-30 T 22-04-2016 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 172 2.7E-20 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 PANTHER PTHR30173 5 173 5.6E-30 T 22-04-2016 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 Pfam PF08281 Sigma-70, region 4 118 168 1.8E-11 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 SUPERFAMILY SSF88659 112 173 1.16E-11 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 Gene3D G3DSA:1.10.1740.10 5 104 2.7E-22 T 22-04-2016 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 Gene3D G3DSA:1.10.10.10 116 173 5.9E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 Pfam PF04542 Sigma-70 region 2 21 87 5.5E-11 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS13280 f16f5d48cbbf2b51524b0a351feeab39 181 SUPERFAMILY SSF88946 5 94 5.49E-20 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00905 c4227b0410066942a995376922461e85 643 PANTHER PTHR11669:SF0 382 443 8.2E-137 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 PANTHER PTHR11669:SF0 8 361 8.2E-137 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 Gene3D G3DSA:3.40.50.300 8 154 6.4E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00905 c4227b0410066942a995376922461e85 643 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 222 348 2.2E-7 T 22-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MED134_RS00905 c4227b0410066942a995376922461e85 643 Pfam PF13177 DNA polymerase III, delta subunit 21 167 1.3E-33 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 SUPERFAMILY SSF52540 33 209 1.05E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00905 c4227b0410066942a995376922461e85 643 Gene3D G3DSA:1.10.8.60 155 229 1.4E-28 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 6 346 3.3E-116 T 22-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MED134_RS00905 c4227b0410066942a995376922461e85 643 SMART SM00382 38 168 3.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS00905 c4227b0410066942a995376922461e85 643 Gene3D G3DSA:1.20.272.10 233 347 3.9E-9 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 SUPERFAMILY SSF48019 233 347 3.15E-16 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 MED134_RS00905 c4227b0410066942a995376922461e85 643 PANTHER PTHR11669 382 443 8.2E-137 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 PANTHER PTHR11669 8 361 8.2E-137 T 22-04-2016 MED134_RS00905 c4227b0410066942a995376922461e85 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 42 60 2.1E-5 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS00905 c4227b0410066942a995376922461e85 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 113 131 2.1E-5 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 PIRSF PIRSF015601 1 233 1.5E-55 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 PANTHER PTHR30027:SF3 1 224 1.7E-51 T 22-04-2016 MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 SUPERFAMILY SSF88697 1 69 2.82E-14 T 22-04-2016 IPR015947 PUA-like domain MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 Pfam PF04452 RNA methyltransferase 17 228 2.3E-56 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 SUPERFAMILY SSF75217 73 230 2.15E-41 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 PANTHER PTHR30027 1 224 1.7E-51 T 22-04-2016 MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 Gene3D G3DSA:3.40.1280.10 1 231 2.0E-66 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS01035 85e5a8a14017d1e67763bb79491dc9f7 233 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 1 226 1.4E-43 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 Gene3D G3DSA:3.40.50.1980 151 254 5.8E-13 T 22-04-2016 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 PANTHER PTHR30535:SF6 1 250 3.2E-37 T 22-04-2016 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 PANTHER PTHR30535 1 250 3.2E-37 T 22-04-2016 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 Gene3D G3DSA:3.40.50.1980 17 134 1.2E-22 T 22-04-2016 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 SUPERFAMILY SSF53807 2 255 8.24E-48 T 22-04-2016 MED134_RS03750 6d9c9055855089541c494cb1f8dcb5a0 263 Pfam PF01497 Periplasmic binding protein 20 226 1.3E-21 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 Gene3D G3DSA:3.20.20.70 7 489 2.2E-200 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 477 7.9E-161 T 22-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SMART SM01240 11 477 0.0 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SUPERFAMILY SSF51412 220 481 1.14E-121 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SUPERFAMILY SSF51412 8 94 1.14E-121 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SMART SM00116 100 148 3.7E-8 T 22-04-2016 IPR000644 CBS domain MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SMART SM00116 161 209 1.4E-7 T 22-04-2016 IPR000644 CBS domain MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 PANTHER PTHR11911:SF6 302 490 7.1E-238 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 PANTHER PTHR11911:SF6 1 284 7.1E-238 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 Pfam PF00571 CBS domain 97 144 2.3E-10 T 22-04-2016 IPR000644 CBS domain MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 Pfam PF00571 CBS domain 153 206 6.4E-10 T 22-04-2016 IPR000644 CBS domain MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 SUPERFAMILY SSF54631 67 208 9.73E-31 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 PIRSF PIRSF000130 1 490 4.2E-205 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 PANTHER PTHR11911 302 490 7.1E-238 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 PANTHER PTHR11911 1 284 7.1E-238 T 22-04-2016 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 459 4.5E-188 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 490 83.584 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 MED134_RS14205 870a1ed5ae709665524ea888426d31da 490 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 22-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 Gene3D G3DSA:2.130.10.140 670 716 1.3E-7 T 22-04-2016 MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 Gene3D G3DSA:2.130.10.140 488 669 1.8E-29 T 22-04-2016 MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 SUPERFAMILY SSF50939 164 426 7.06E-67 T 22-04-2016 IPR011040 Sialidases MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 SUPERFAMILY SSF50939 21 134 7.06E-67 T 22-04-2016 IPR011040 Sialidases MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 Pfam PF15902 Sortilin, neurotensin receptor 3, 119 243 2.8E-12 T 22-04-2016 IPR031778 Sortilin, N-terminal MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 Pfam PF15902 Sortilin, neurotensin receptor 3, 635 718 1.5E-9 T 22-04-2016 IPR031778 Sortilin, N-terminal MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 SUPERFAMILY SSF110296 495 708 2.88E-48 T 22-04-2016 MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 SUPERFAMILY SSF110296 305 395 2.88E-48 T 22-04-2016 MED134_RS02330 cbf7a0969af0b5b53cf4689540bb3f16 1064 Gene3D G3DSA:2.130.10.140 40 414 4.5E-85 T 22-04-2016 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 SUPERFAMILY SSF51735 131 261 8.24E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 93 1.0E-19 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 PANTHER PTHR21089 1 260 2.7E-60 T 22-04-2016 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 Gene3D G3DSA:3.40.192.10 6 111 1.5E-32 T 22-04-2016 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 PANTHER PTHR21089:SF1 1 260 2.7E-60 T 22-04-2016 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 SUPERFAMILY SSF53223 9 106 3.05E-23 T 22-04-2016 MED134_RS04245 4062afcb341c5fe5b7d160d43450aeb8 262 Gene3D G3DSA:3.40.50.720 112 261 1.2E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 152 175 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 19 47 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 87 107 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 123 149 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 61 84 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 181 203 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PRINTS PR00169 Potassium channel signature 210 236 4.5E-32 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PANTHER PTHR11537 5 285 1.1E-95 T 22-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 Gene3D G3DSA:1.10.287.70 27 236 2.0E-49 T 22-04-2016 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 PANTHER PTHR11537:SF137 5 285 1.1E-95 T 22-04-2016 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 Pfam PF00520 Ion transport protein 26 238 8.7E-30 T 22-04-2016 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MED134_RS05155 e688a48e76244c8c99381b44eee85f4b 286 SUPERFAMILY SSF81324 25 237 9.99E-53 T 22-04-2016 MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 PANTHER PTHR10209:SF146 1 316 1.2E-89 T 22-04-2016 MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 PANTHER PTHR10209 1 316 1.2E-89 T 22-04-2016 MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 Gene3D G3DSA:2.60.120.330 2 309 2.0E-89 T 22-04-2016 IPR027443 Isopenicillin N synthase-like MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 4 112 2.2E-26 T 22-04-2016 IPR026992 Non-haem dioxygenase N-terminal domain MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 SUPERFAMILY SSF51197 3 310 2.13E-86 T 22-04-2016 MED134_RS02675 c561aeefd4db508094646fee6b4b2424 316 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 176 274 1.3E-15 T 22-04-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3038 3148 5.75E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2278 2385 2.88E-16 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3695 3803 4.97E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1699 1813 7.32E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 4131 4238 2.22E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF13585 C-terminal domain of CHU protein family 4498 4593 9.2E-20 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 4022 4129 1.7E-16 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1815 1929 6.02E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1467 1581 5.62E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2495 2603 3.4E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2932 3039 1.57E-16 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3911 4020 1.12E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1931 2045 6.15E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2605 2713 3.14E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2812 2904 5.8E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3357 3449 3.5E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2594 2686 6.7E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1805 1904 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2921 3013 5.8E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1109 1208 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 992 1092 1.8E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2269 2359 2.8E-8 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2376 2468 9.1E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2703 2795 5.8E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1225 1324 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3793 3885 3.5E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3684 3777 2.7E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 4011 4103 9.1E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1921 2020 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 4120 4213 5.9E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2153 2252 2.8E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2037 2136 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1573 1672 5.2E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 2485 2577 1.2E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3902 3994 3.0E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1341 1440 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3030 3122 2.8E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3466 3558 8.8E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1457 1556 3.7E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3139 3231 4.5E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 1689 1788 2.1E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3248 3340 6.9E-10 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 Pfam PF03160 Calx-beta domain 3575 3667 1.2E-9 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2822 2931 3.79E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2384 2494 1.96E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3258 3367 5.36E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3475 3584 4.32E-16 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3803 3911 7.85E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF103647 404 468 2.88E-6 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3148 3257 1.96E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2047 2161 6.02E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1351 1465 5.89E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 894 999 1.83E-6 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1583 1697 4.97E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2163 2277 9.55E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF117074 305 367 1.1E-5 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1119 1233 6.28E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 998 1117 4.58E-21 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3581 3693 7.98E-18 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 3367 3475 7.19E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 2713 2822 3.4E-17 T 22-04-2016 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1107 1209 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 991 1093 0.0014 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2811 2907 0.018 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1687 1789 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3138 3234 0.045 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1919 2021 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1339 1441 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2375 2471 0.03 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3901 3997 0.026 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2702 2798 0.018 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 4119 4215 0.04 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2151 2253 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 4010 4106 0.047 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3574 3670 0.094 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3247 3343 0.035 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2920 3016 0.018 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3792 3888 0.036 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1803 1905 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2267 2362 0.079 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3683 3779 0.024 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2593 2689 0.018 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1223 1325 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2484 2580 0.03 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3029 3125 0.033 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 2035 2137 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3356 3452 0.036 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1571 1673 0.0054 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 1455 1557 0.0048 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SMART SM00237 3465 3561 0.034 T 22-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 MED134_RS10315 25a4dd865f092f712ed2dc7e947adedb 4595 SUPERFAMILY SSF141072 1234 1349 6.8E-21 T 22-04-2016 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Pfam PF00108 Thiolase, N-terminal domain 5 264 2.4E-61 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Pfam PF02803 Thiolase, C-terminal domain 272 393 1.0E-44 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 PANTHER PTHR18919 1 397 1.1E-171 T 22-04-2016 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 SUPERFAMILY SSF53901 272 394 1.63E-40 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 22-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 PIRSF PIRSF000429 1 397 2.4E-120 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 1.5E-129 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 22-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Gene3D G3DSA:3.40.47.10 278 394 2.3E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Gene3D G3DSA:3.40.47.10 148 186 2.3E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 SUPERFAMILY SSF53901 1 269 3.76E-65 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 PANTHER PTHR18919:SF87 1 397 1.1E-171 T 22-04-2016 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Gene3D G3DSA:3.40.47.10 187 276 1.5E-57 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 Gene3D G3DSA:3.40.47.10 4 126 1.5E-57 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01145 4a1ba48a038f8f441fa9a471b3ab80e5 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 MED134_RS09685 050bf2ed55a8f49756a196472a84c737 356 SUPERFAMILY SSF56235 39 190 9.5E-98 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS09685 050bf2ed55a8f49756a196472a84c737 356 SUPERFAMILY SSF56235 218 350 9.5E-98 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS09685 050bf2ed55a8f49756a196472a84c737 356 PANTHER PTHR10188:SF24 16 356 4.8E-134 T 22-04-2016 MED134_RS09685 050bf2ed55a8f49756a196472a84c737 356 Pfam PF01112 Asparaginase 41 353 9.1E-122 T 22-04-2016 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MED134_RS09685 050bf2ed55a8f49756a196472a84c737 356 PANTHER PTHR10188 16 356 4.8E-134 T 22-04-2016 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Pfam PF07719 Tetratricopeptide repeat 238 266 3.6E-5 T 22-04-2016 IPR013105 Tetratricopeptide repeat 2 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 PANTHER PTHR23083 23 385 2.2E-35 T 22-04-2016 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Pfam PF13181 Tetratricopeptide repeat 50 82 0.0049 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Pfam PF13181 Tetratricopeptide repeat 304 336 1.8E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SUPERFAMILY SSF48452 28 345 1.52E-28 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Gene3D G3DSA:1.25.40.10 210 252 4.0E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Gene3D G3DSA:1.25.40.10 123 209 6.5E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Gene3D G3DSA:1.25.40.10 25 122 7.4E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 Gene3D G3DSA:1.25.40.10 253 345 3.9E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 234 267 0.0043 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 166 199 27.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 303 336 0.014 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 268 301 26.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 200 233 370.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10350 46cc754ccbfb2e3123594654c945e5fc 400 SMART SM00028 50 83 0.042 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 8 76 3.0E-9 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 Pfam PF10369 Small subunit of acetolactate synthase 89 161 5.6E-17 T 22-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 Gene3D G3DSA:3.30.70.260 6 82 2.4E-19 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 Pfam PF01842 ACT domain 8 70 7.7E-8 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 SUPERFAMILY SSF55021 80 163 3.66E-17 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 Gene3D G3DSA:3.30.70.1150 89 166 1.2E-13 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 PANTHER PTHR30239:SF0 3 179 1.5E-27 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 8 162 5.9E-25 T 22-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 SUPERFAMILY SSF55021 7 80 5.8E-13 T 22-04-2016 MED134_RS04730 63a947eb5208c9dda67e812ec80e652f 186 PANTHER PTHR30239 3 179 1.5E-27 T 22-04-2016 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Gene3D G3DSA:3.40.50.300 566 801 2.1E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 860 7.3E-275 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Gene3D G3DSA:3.40.1170.10 3 118 9.5E-47 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Pfam PF01624 MutS domain I 7 117 4.4E-39 T 22-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SMART SM00534 609 797 3.3E-105 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SUPERFAMILY SSF52540 566 801 2.18E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 PANTHER PTHR11361:SF86 1 869 0.0 T 22-04-2016 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Gene3D G3DSA:3.30.420.110 124 254 1.4E-36 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Pfam PF05188 MutS domain II 126 251 1.2E-17 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Pfam PF05190 MutS family domain IV 427 518 9.9E-27 T 22-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 690 706 - T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 PANTHER PTHR11361 1 869 0.0 T 22-04-2016 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Pfam PF00488 MutS domain V 613 800 2.2E-79 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SUPERFAMILY SSF55271 4 112 2.09E-40 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SMART SM00533 282 590 4.9E-90 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Gene3D G3DSA:1.10.1420.10 262 465 4.4E-45 T 22-04-2016 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SUPERFAMILY SSF48334 266 565 6.15E-80 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 PIRSF PIRSF037677 2 864 3.6E-160 T 22-04-2016 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Pfam PF05192 MutS domain III 269 557 8.0E-34 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 SUPERFAMILY SSF53150 112 265 6.28E-40 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MED134_RS07365 98e940e7b5b9e30fd675327f4ec2ea2a 872 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 855 23.815 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 PANTHER PTHR22916 2 136 9.4E-46 T 22-04-2016 MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 Pfam PF00535 Glycosyl transferase family 2 5 121 1.4E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 Gene3D G3DSA:3.90.550.10 2 246 8.7E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 PANTHER PTHR22916:SF26 157 265 9.4E-46 T 22-04-2016 MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 PANTHER PTHR22916 157 265 9.4E-46 T 22-04-2016 MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 SUPERFAMILY SSF53448 2 276 7.11E-47 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS03640 b3301b6c23b2d9fd6d7136a1795a6a92 329 PANTHER PTHR22916:SF26 2 136 9.4E-46 T 22-04-2016 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 Gene3D G3DSA:3.40.47.10 257 383 2.0E-18 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 PANTHER PTHR11712 5 383 8.4E-28 T 22-04-2016 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 SUPERFAMILY SSF53901 3 382 4.61E-33 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 249 346 6.4E-13 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 Gene3D G3DSA:3.40.47.10 3 234 1.4E-27 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 PANTHER PTHR11712:SF277 5 383 8.4E-28 T 22-04-2016 MED134_RS07920 c99e34ffe44091ec076776d9c19f8560 384 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 234 8.6E-21 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 PANTHER PTHR30218:SF0 1 681 1.8E-236 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Gene3D G3DSA:3.30.870.10 497 682 7.3E-67 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 SUPERFAMILY SSF143724 113 311 2.35E-43 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Pfam PF13089 Polyphosphate kinase N-terminal domain 9 115 2.3E-32 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Gene3D G3DSA:3.30.1840.10 112 298 8.2E-38 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 9 676 2.0E-202 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Pfam PF02503 Polyphosphate kinase middle domain 126 319 1.5E-36 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 SUPERFAMILY SSF56024 498 682 6.02E-65 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 PIRSF PIRSF015589 2 684 1.6E-212 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Pfam PF13090 Polyphosphate kinase C-terminal domain 329 675 5.9E-133 T 22-04-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 SUPERFAMILY SSF140356 6 111 4.45E-29 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 SUPERFAMILY SSF56024 316 490 2.62E-44 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 PANTHER PTHR30218 1 681 1.8E-236 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Gene3D G3DSA:3.30.870.10 316 491 1.1E-57 T 22-04-2016 MED134_RS02695 1af59604606933760e249850cb7e3e9c 684 Gene3D G3DSA:1.20.58.310 5 111 1.0E-29 T 22-04-2016 MED134_RS09680 f6d06276bf95ec049d16886c2d3855a3 165 Pfam PF00188 Cysteine-rich secretory protein family 52 155 4.1E-12 T 22-04-2016 IPR014044 CAP domain MED134_RS09680 f6d06276bf95ec049d16886c2d3855a3 165 PANTHER PTHR31157 46 163 2.5E-16 T 22-04-2016 MED134_RS09680 f6d06276bf95ec049d16886c2d3855a3 165 SUPERFAMILY SSF55797 47 164 8.63E-17 T 22-04-2016 IPR014044 CAP domain MED134_RS09680 f6d06276bf95ec049d16886c2d3855a3 165 Gene3D G3DSA:3.40.33.10 46 161 1.9E-8 T 22-04-2016 IPR014044 CAP domain MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 290 55.131 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 SUPERFAMILY SSF51569 2 289 2.51E-88 T 22-04-2016 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 SMART SM01130 3 291 7.6E-106 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 166 - T 22-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PIRSF PIRSF001365 1 291 5.6E-80 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 Pfam PF00701 Dihydrodipicolinate synthetase family 5 289 1.3E-75 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.2E-23 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.2E-23 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.2E-23 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.2E-23 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PANTHER PTHR12128 4 291 3.4E-104 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 PANTHER PTHR12128:SF34 4 291 3.4E-104 T 22-04-2016 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 Gene3D G3DSA:3.20.20.70 1 290 7.8E-99 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05220 666890b0a4b2d3e423cbf7df0ea427f2 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 9 289 1.1E-89 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 TIGRFAM TIGR04057 SusC_RagA_signa: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region 229 259 4.7E-16 T 22-04-2016 IPR023997 TonB-dependent outer membrane protein SusC/RagA, conserved site UniPathway: UPA00153 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 28 813 9.7E-152 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Pfam PF13715 CarboxypepD_reg-like domain 28 109 1.7E-18 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Gene3D G3DSA:2.60.40.1120 28 109 4.1E-12 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF49464 27 107 1.57E-17 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532:SF57 1 193 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532:SF57 220 375 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532:SF57 410 516 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532:SF57 574 990 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532 1 193 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532 220 375 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532 410 516 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 PANTHER PTHR11532 574 990 1.1E-136 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Pfam PF07715 TonB-dependent Receptor Plug Domain 119 253 7.0E-16 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF56935 321 409 1.26E-81 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF56935 442 780 1.26E-81 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF56935 105 277 1.26E-81 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF56935 821 865 1.26E-81 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 SUPERFAMILY SSF56935 896 967 1.26E-81 T 22-04-2016 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Gene3D G3DSA:2.40.170.20 330 983 1.2E-49 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Gene3D G3DSA:2.40.170.20 254 278 1.2E-49 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07370 9cdb1f8d600fd9e3e0874a65d8291635 992 Gene3D G3DSA:2.170.130.10 110 253 7.8E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 SUPERFAMILY SSF63380 475 594 2.6E-13 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Gene3D G3DSA:3.40.50.360 335 486 1.1E-27 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 SUPERFAMILY SSF52343 590 731 2.1E-27 T 22-04-2016 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Pfam PF03929 PepSY-associated TM region 9 325 6.1E-33 T 22-04-2016 IPR005625 PepSY-associated TM protein MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 PANTHER PTHR19384:SF17 544 731 6.4E-26 T 22-04-2016 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 PANTHER PTHR19384 544 731 6.4E-26 T 22-04-2016 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Gene3D G3DSA:3.40.50.80 588 729 2.2E-26 T 22-04-2016 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Pfam PF00175 Oxidoreductase NAD-binding domain 602 701 4.7E-9 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 PRINTS PR00369 Flavodoxin signature 390 401 2.08E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 PRINTS PR00369 Flavodoxin signature 344 357 2.08E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 PRINTS PR00369 Flavodoxin signature 420 430 2.08E-7 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Gene3D G3DSA:2.40.30.10 500 583 6.2E-8 T 22-04-2016 MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 SUPERFAMILY SSF52218 341 490 1.02E-31 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS00580 b779ff1c7f3148f253efa7299b6949c5 731 Pfam PF00258 Flavodoxin 345 455 4.8E-18 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 SUPERFAMILY SSF56553 51 175 1.15E-37 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 321 34.548 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Gene3D G3DSA:2.170.120.12 64 174 5.7E-41 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Gene3D G3DSA:3.30.1360.10 9 63 5.0E-10 T 22-04-2016 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 9.0E-20 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 225 9.9E-23 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 PANTHER PTHR32108:SF0 3 322 1.6E-109 T 22-04-2016 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 PANTHER PTHR32108 3 322 1.6E-109 T 22-04-2016 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 SUPERFAMILY SSF47789 255 327 1.96E-21 T 22-04-2016 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 310 2.0E-21 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 Gene3D G3DSA:1.10.150.20 249 328 7.1E-28 T 22-04-2016 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 SMART SM00662 21 231 4.0E-73 T 22-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 SUPERFAMILY SSF55257 7 51 7.75E-30 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 SUPERFAMILY SSF55257 176 230 7.75E-30 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 263 322 2.0E-19 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS12360 90410d0f57c2555959b9dbd54888f6b0 330 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 22 321 4.9E-111 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 SUPERFAMILY SSF88659 107 170 8.04E-17 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 Pfam PF04542 Sigma-70 region 2 21 85 1.9E-15 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 167 4.7E-27 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 Pfam PF08281 Sigma-70, region 4 112 161 2.3E-14 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 PANTHER PTHR30173:SF21 1 169 4.3E-42 T 22-04-2016 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 SUPERFAMILY SSF88946 4 103 1.12E-19 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 Gene3D G3DSA:1.10.1740.10 2 106 9.1E-24 T 22-04-2016 MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 Gene3D G3DSA:1.10.10.10 111 169 2.0E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08805 a73cfe843a939af0b24f7715863225fa 181 PANTHER PTHR30173 1 169 4.3E-42 T 22-04-2016 MED134_RS12180 5a51755885f0a73358159750ad073698 258 PANTHER PTHR22936:SF11 37 221 2.4E-40 T 22-04-2016 MED134_RS12180 5a51755885f0a73358159750ad073698 258 PANTHER PTHR22936 37 221 2.4E-40 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 MED134_RS12180 5a51755885f0a73358159750ad073698 258 Gene3D G3DSA:1.20.1540.10 21 185 4.6E-13 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS12180 5a51755885f0a73358159750ad073698 258 Pfam PF01694 Rhomboid family 55 186 8.1E-17 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS12180 5a51755885f0a73358159750ad073698 258 SUPERFAMILY SSF144091 19 186 3.14E-26 T 22-04-2016 MED134_RS03590 49945e6f7345a7f3ba02f0557653f64a 263 Pfam PF02754 Cysteine-rich domain 148 235 4.8E-16 T 22-04-2016 IPR004017 Cysteine-rich domain MED134_RS03590 49945e6f7345a7f3ba02f0557653f64a 263 Pfam PF02754 Cysteine-rich domain 22 108 8.3E-17 T 22-04-2016 IPR004017 Cysteine-rich domain MED134_RS03590 49945e6f7345a7f3ba02f0557653f64a 263 PANTHER PTHR11921 3 263 9.5E-116 T 22-04-2016 MED134_RS03590 49945e6f7345a7f3ba02f0557653f64a 263 PANTHER PTHR11921:SF22 3 263 9.5E-116 T 22-04-2016 MED134_RS09590 31dc5085df784f81dfead2105ce15c53 292 Pfam PF02687 FtsX-like permease family 169 279 8.9E-10 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS09590 31dc5085df784f81dfead2105ce15c53 292 PIRSF PIRSF003097 2 285 1.1E-78 T 22-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 MED134_RS09590 31dc5085df784f81dfead2105ce15c53 292 PANTHER PTHR30489 89 288 6.0E-19 T 22-04-2016 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Pfam PF00919 Uncharacterized protein family UPF0004 25 125 2.4E-31 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Pfam PF01938 TRAM domain 415 476 3.7E-14 T 22-04-2016 IPR002792 TRAM domain MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 SMART SM00729 169 400 2.0E-56 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Gene3D G3DSA:3.80.30.20 167 412 1.5E-78 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 173 193 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 25 476 7.2E-137 T 22-04-2016 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Gene3D G3DSA:2.40.50.140 419 476 6.5E-4 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 24 477 67.304 T 22-04-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 PANTHER PTHR11918 6 476 9.9E-208 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 25 473 2.9E-136 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 SUPERFAMILY SSF102114 163 415 1.96E-58 T 22-04-2016 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 PANTHER PTHR11918:SF43 6 476 9.9E-208 T 22-04-2016 MED134_RS06125 485590dca40e9c62312186e3ecafee60 484 Pfam PF04055 Radical SAM superfamily 173 360 7.2E-32 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 204 2.3E-32 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 209 26.658 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 Gene3D G3DSA:3.20.20.70 1 206 1.1E-53 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 PANTHER PTHR22854 1 203 1.0E-32 T 22-04-2016 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 PANTHER PTHR22854:SF6 1 203 1.0E-32 T 22-04-2016 MED134_RS13025 fba86e152403f6325dcea5e3694ccf12 209 SUPERFAMILY SSF51366 1 207 3.14E-44 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 TIGRFAM TIGR04057 SusC_RagA_signa: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region 216 246 3.0E-19 T 22-04-2016 IPR023997 TonB-dependent outer membrane protein SusC/RagA, conserved site UniPathway: UPA00153 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532:SF57 595 1043 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532:SF57 1 187 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532:SF57 207 364 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532:SF57 461 522 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532 595 1043 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532 1 187 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532 207 364 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 PANTHER PTHR11532 461 522 1.4E-203 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.60.40.1120 26 103 1.9E-12 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Pfam PF13715 CarboxypepD_reg-like domain 26 104 9.4E-20 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Pfam PF07715 TonB-dependent Receptor Plug Domain 114 240 1.0E-18 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.40.170.20 887 1045 5.5E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.40.170.20 599 823 5.5E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.40.170.20 287 549 5.5E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.40.170.20 241 254 5.5E-60 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 Gene3D G3DSA:2.170.130.10 104 240 7.0E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF49464 24 98 3.01E-19 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 24 570 4.2E-115 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 877 922 5.13E-89 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 420 521 5.13E-89 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 572 816 5.13E-89 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 302 391 5.13E-89 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 949 1045 5.13E-89 T 22-04-2016 MED134_RS10655 12b022e1512cdba45d0aba68d33cac4b 1045 SUPERFAMILY SSF56935 101 263 5.13E-89 T 22-04-2016 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 PANTHER PTHR11695 15 326 4.5E-92 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 Gene3D G3DSA:3.40.50.720 151 260 1.6E-24 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 4.4E-9 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 SMART SM00829 10 325 7.1E-31 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 SUPERFAMILY SSF51735 119 270 2.35E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 Pfam PF13602 Zinc-binding dehydrogenase 193 325 2.8E-20 T 22-04-2016 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 PANTHER PTHR11695:SF294 15 326 4.5E-92 T 22-04-2016 MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 SUPERFAMILY SSF50129 1 153 5.93E-35 T 22-04-2016 IPR011032 GroES-like MED134_RS00540 31d075a94db657ec648473ba90c983e4 327 Gene3D G3DSA:3.90.180.10 1 150 7.4E-41 T 22-04-2016 IPR011032 GroES-like MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 390 2.9E-135 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 SUPERFAMILY SSF53901 4 267 2.44E-84 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Pfam PF02803 Thiolase, C-terminal domain 270 390 7.8E-43 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 22-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 PANTHER PTHR18919 1 393 2.3E-208 T 22-04-2016 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 PIRSF PIRSF000429 1 393 4.4E-125 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 SUPERFAMILY SSF53901 270 391 9.75E-36 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 PANTHER PTHR18919:SF81 1 393 2.3E-208 T 22-04-2016 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Gene3D G3DSA:3.40.47.10 276 391 1.1E-54 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Gene3D G3DSA:3.40.47.10 143 193 1.1E-54 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 1.0E-99 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Gene3D G3DSA:3.40.47.10 5 124 1.4E-76 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS01955 3a5bfaa90b56e8e283a358cb39ea8fa4 393 Gene3D G3DSA:3.40.47.10 194 275 1.4E-76 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 SUPERFAMILY SSF52540 799 824 6.91E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 SUPERFAMILY SSF52540 5 63 6.91E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 SUPERFAMILY SSF52540 104 206 6.91E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 SUPERFAMILY SSF52540 331 761 6.91E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Pfam PF12705 PD-(D/E)XK nuclease superfamily 900 1024 6.1E-7 T 22-04-2016 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070:SF24 104 210 1.5E-70 T 22-04-2016 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070:SF24 798 1037 1.5E-70 T 22-04-2016 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070:SF24 8 75 1.5E-70 T 22-04-2016 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070:SF24 324 761 1.5E-70 T 22-04-2016 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 450 3.1E-39 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070 104 210 1.5E-70 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070 798 1037 1.5E-70 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070 8 75 1.5E-70 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 PANTHER PTHR11070 324 761 1.5E-70 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Gene3D G3DSA:3.40.50.300 465 577 4.2E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Gene3D G3DSA:3.40.50.300 715 855 4.2E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Pfam PF13361 UvrD-like helicase C-terminal domain 720 819 2.1E-9 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Pfam PF13361 UvrD-like helicase C-terminal domain 462 577 3.0E-8 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Gene3D G3DSA:3.40.50.300 341 452 8.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Gene3D G3DSA:3.40.50.300 5 59 8.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08985 7b6d800236aac0f2e9f3d7b7f0697db1 1045 Gene3D G3DSA:3.40.50.300 112 182 8.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 88 2.6E-18 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 Pfam PF00589 Phage integrase family 112 283 1.5E-47 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 PANTHER PTHR30349 4 297 3.2E-107 T 22-04-2016 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 PANTHER PTHR30349:SF5 4 297 3.2E-107 T 22-04-2016 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 297 1.1E-104 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 29.335 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 Gene3D G3DSA:1.10.150.130 4 98 2.1E-23 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 SUPERFAMILY SSF56349 4 291 2.15E-61 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS04505 43d991556c188c91d5c952ca730814d3 299 Gene3D G3DSA:1.10.443.10 108 297 2.0E-55 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS07425 b58763f37c6f23bbc2fea97940f9617e 886 SUPERFAMILY SSF54001 294 542 7.36E-11 T 22-04-2016 MED134_RS07425 b58763f37c6f23bbc2fea97940f9617e 886 SUPERFAMILY SSF54001 211 398 1.63E-11 T 22-04-2016 MED134_RS07425 b58763f37c6f23bbc2fea97940f9617e 886 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 63 226 5.1E-36 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 MED134_RS07425 b58763f37c6f23bbc2fea97940f9617e 886 Pfam PF10754 Protein of unknown function (DUF2569) 692 841 8.0E-35 T 22-04-2016 IPR019690 Protein of unknown function DUF2569 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 SUPERFAMILY SSF55021 364 436 1.57E-9 T 22-04-2016 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 PANTHER PTHR21499 3 436 3.0E-113 T 22-04-2016 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 SUPERFAMILY SSF55021 295 382 3.07E-17 T 22-04-2016 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 SUPERFAMILY SSF53633 1 289 4.32E-65 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 Pfam PF00696 Amino acid kinase family 2 276 7.4E-34 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 435 6.4E-85 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 PIRSF PIRSF000726 1 439 7.7E-89 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 Gene3D G3DSA:3.40.1160.10 104 290 8.0E-54 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 Gene3D G3DSA:3.40.1160.10 1 46 8.0E-54 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS10975 16ce6de70fe9155870f40bcda072f976 441 PANTHER PTHR21499:SF3 3 436 3.0E-113 T 22-04-2016 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 5 255 32.782 T 22-04-2016 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 Gene3D G3DSA:3.40.1210.10 5 255 1.1E-86 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 7 244 4.6E-62 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 Pfam PF01975 Survival protein SurE 7 193 1.1E-56 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 PANTHER PTHR30457 1 255 5.7E-87 T 22-04-2016 MED134_RS06430 2ca868d545f745e4cb5fe116db32e47d 257 SUPERFAMILY SSF64167 6 255 2.75E-76 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PANTHER PTHR19139 5 201 1.8E-85 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 153 175 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 41 65 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 190 210 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 78 97 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PRINTS PR00783 Major intrinsic protein family signature 122 140 1.7E-43 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 SUPERFAMILY SSF81338 1 210 6.67E-63 T 22-04-2016 IPR023271 Aquaporin-like MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 204 2.1E-52 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 ProSitePatterns PS00221 MIP family signature. 59 67 - T 22-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 PANTHER PTHR19139:SF144 5 201 1.8E-85 T 22-04-2016 MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 Gene3D G3DSA:1.20.1080.10 1 213 1.3E-63 T 22-04-2016 IPR023271 Aquaporin-like MED134_RS14080 f16df1ecd2ec19a4508b779edb457f09 218 Pfam PF00230 Major intrinsic protein 2 204 1.1E-49 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 SUPERFAMILY SSF51206 6 147 1.96E-26 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 Gene3D G3DSA:1.10.10.10 148 218 2.3E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 Pfam PF13545 Crp-like helix-turn-helix domain 152 218 9.0E-9 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 Gene3D G3DSA:2.60.120.10 4 143 8.0E-23 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 PANTHER PTHR24567 4 219 2.1E-31 T 22-04-2016 MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 SMART SM00100 18 134 6.0E-8 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 Pfam PF00027 Cyclic nucleotide-binding domain 32 119 2.2E-15 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS00880 c0db175c5a9f7c6ac617251103cd1148 221 SUPERFAMILY SSF46785 148 218 3.02E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 17 435 7.4E-108 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 SUPERFAMILY SSF103491 2 431 1.11E-106 T 22-04-2016 IPR023201 SecY subunit domain MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 Hamap MF_01465 Protein translocase subunit SecY [secY]. 7 440 27.287 T 22-04-2016 IPR026593 Protein translocase subunit SecY MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 Gene3D G3DSA:1.10.3370.10 4 444 8.4E-137 T 22-04-2016 IPR023201 SecY subunit domain MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PANTHER PTHR10906 4 450 1.2E-159 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PIRSF PIRSF004557 1 448 1.8E-112 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 22-04-2016 IPR030659 SecY conserved site MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 Pfam PF00344 SecY translocase 73 424 1.4E-103 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 20 38 1.0E-85 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 PANTHER PTHR10906:SF2 4 450 1.2E-159 T 22-04-2016 MED134_RS12335 34f919299eb341216b4984bbfedcafd8 450 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 22-04-2016 IPR030659 SecY conserved site MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 PANTHER PTHR24220:SF470 7 204 5.3E-80 T 22-04-2016 MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 Gene3D G3DSA:3.40.50.300 2 206 1.4E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 PANTHER PTHR24220 7 204 5.3E-80 T 22-04-2016 MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 SUPERFAMILY SSF52540 18 221 2.41E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 Pfam PF00005 ABC transporter 21 169 2.7E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13650 5c88c3f2dd8e4c1d8283919c1201adfe 227 SMART SM00382 30 215 2.4E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS00845 304f520a5e66196171ec021cdd88dec8 285 SUPERFAMILY SSF109998 30 155 2.98E-5 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Gene3D G3DSA:1.10.601.10 12 123 8.2E-49 T 22-04-2016 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Pfam PF00140 Sigma-70 factor, region 1.2 17 48 1.5E-14 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 SUPERFAMILY SSF88946 14 123 1.88E-41 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PANTHER PTHR30603 21 286 1.3E-109 T 22-04-2016 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Gene3D G3DSA:1.10.10.10 218 286 5.0E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PANTHER PTHR30603:SF0 21 286 1.3E-109 T 22-04-2016 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 SUPERFAMILY SSF88659 188 286 3.36E-25 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Pfam PF04542 Sigma-70 region 2 56 123 1.4E-16 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 275 3.5E-36 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PRINTS PR00046 Major sigma-70 factor signature 247 262 1.1E-24 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PRINTS PR00046 Major sigma-70 factor signature 226 238 1.1E-24 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PRINTS PR00046 Major sigma-70 factor signature 102 110 1.1E-24 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PRINTS PR00046 Major sigma-70 factor signature 262 273 1.1E-24 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.1E-24 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 PIRSF PIRSF000770 7 284 2.4E-38 T 22-04-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Pfam PF04539 Sigma-70 region 3 135 208 3.4E-17 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Pfam PF04545 Sigma-70, region 4 222 275 4.5E-18 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 Gene3D G3DSA:1.10.10.10 127 174 1.7E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12680 1ce4ec146f49455c9664f4722e5b8e8e 287 SUPERFAMILY SSF88659 127 199 2.09E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 165 182 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 71 88 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 23 45 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 183 201 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 115 137 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PRINTS PR00775 90kDa heat shock protein signature 89 106 1.3E-38 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 Gene3D G3DSA:3.30.565.10 3 241 7.2E-64 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 Pfam PF00183 Hsp90 protein 221 629 3.3E-46 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PANTHER PTHR11528:SF44 16 604 9.8E-139 T 22-04-2016 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PANTHER PTHR11528 16 604 9.8E-139 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 2.4E-12 T 22-04-2016 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 SUPERFAMILY SSF110942 536 628 2.09E-5 T 22-04-2016 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 22-04-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 PIRSF PIRSF002583 1 629 2.8E-148 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 SUPERFAMILY SSF55874 2 206 5.76E-57 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS03975 33f3830055fe0361b54423e06f588d4f 629 SUPERFAMILY SSF54211 234 486 7.05E-60 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 Gene3D G3DSA:3.30.360.10 109 203 3.8E-26 T 22-04-2016 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 SUPERFAMILY SSF51735 204 234 3.02E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 SUPERFAMILY SSF51735 1 97 3.02E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 233 24.996 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 26 233 2.0E-44 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 Gene3D G3DSA:3.40.50.720 1 108 4.1E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 PIRSF PIRSF000161 1 234 9.0E-59 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 98 1.8E-15 T 22-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 SUPERFAMILY SSF55347 100 205 3.92E-22 T 22-04-2016 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 101 232 8.1E-37 T 22-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS05385 638c9947fb165eb45bca51f78a227f97 234 PANTHER PTHR20836 1 234 9.9E-53 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 Gene3D G3DSA:3.20.20.190 15 347 1.0E-89 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 PANTHER PTHR23344:SF7 240 345 5.0E-97 T 22-04-2016 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 PANTHER PTHR23344 240 345 5.0E-97 T 22-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 PANTHER PTHR23344 8 218 5.0E-97 T 22-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 SUPERFAMILY SSF51695 14 346 1.91E-77 T 22-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 PANTHER PTHR23344:SF7 8 218 5.0E-97 T 22-04-2016 MED134_RS14015 9297b8d5d9315a891b8b7622d7929fd2 355 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 21 342 3.4E-50 T 22-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 SUPERFAMILY SSF52922 534 666 9.82E-29 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Pfam PF00676 Dehydrogenase E1 component 27 323 2.4E-69 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 PANTHER PTHR11624:SF21 338 668 2.5E-142 T 22-04-2016 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 PANTHER PTHR11624:SF21 22 299 2.5E-142 T 22-04-2016 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 PANTHER PTHR11624 338 668 2.5E-142 T 22-04-2016 IPR033247 Transketolase family MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 PANTHER PTHR11624 22 299 2.5E-142 T 22-04-2016 IPR033247 Transketolase family MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Gene3D G3DSA:3.40.50.970 14 336 1.1E-104 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Gene3D G3DSA:3.40.50.970 348 541 1.7E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 SUPERFAMILY SSF52518 13 337 1.12E-85 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Gene3D G3DSA:3.40.50.920 543 654 3.0E-31 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Pfam PF02780 Transketolase, C-terminal domain 539 654 4.9E-27 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 2.2E-38 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 SMART SM00861 351 524 9.9E-51 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS02665 ff03544f66d4f6ef656817b6280dfaa7 668 SUPERFAMILY SSF52518 351 538 4.81E-60 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS14530 a38d0bb541b48c403cbbfe84d28164a0 347 SMART SM00631 22 242 1.1E-4 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS14530 a38d0bb541b48c403cbbfe84d28164a0 347 Pfam PF00246 Zinc carboxypeptidase 27 138 6.8E-19 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS14530 a38d0bb541b48c403cbbfe84d28164a0 347 SUPERFAMILY SSF53187 27 273 1.92E-43 T 22-04-2016 MED134_RS14530 a38d0bb541b48c403cbbfe84d28164a0 347 Gene3D G3DSA:3.40.630.10 26 249 1.4E-33 T 22-04-2016 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 303 3.3E-24 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 Gene3D G3DSA:3.40.50.1370 4 144 4.2E-45 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 1.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 1.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 137 148 1.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.7E-20 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 Gene3D G3DSA:3.40.50.1370 145 291 1.5E-46 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 150 5.7E-33 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 6 306 38.591 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PANTHER PTHR11405:SF16 7 309 3.6E-131 T 22-04-2016 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PANTHER PTHR11405 7 309 3.6E-131 T 22-04-2016 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 SUPERFAMILY SSF53671 3 306 1.7E-91 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 136 153 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 81 90 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 43 65 2.6E-30 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00975 d7057fed4f1cca88e16a523260ffb9aa 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 7 303 4.1E-94 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 SUPERFAMILY SSF55205 1 436 7.52E-103 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 426 5.5E-61 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 435 4.0E-131 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 Gene3D G3DSA:3.65.10.10 229 436 1.6E-48 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 436 33.427 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 PANTHER PTHR21090 1 436 1.5E-126 T 22-04-2016 MED134_RS14010 fd0d2d1e1460b47d029dcb6abc81532e 437 Gene3D G3DSA:3.65.10.10 21 228 1.5E-52 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS09045 b50a477ca7a876591c49809f492377dc 250 SUPERFAMILY SSF49464 20 101 1.57E-5 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 PANTHER PTHR10173 3 129 5.8E-59 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 PANTHER PTHR10173:SF18 3 129 5.8E-59 T 22-04-2016 MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 Pfam PF01641 SelR domain 11 128 1.2E-51 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 127 4.4E-50 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 Gene3D G3DSA:2.170.150.20 2 128 1.6E-58 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS04485 99fffa9bca5df902bbcd3a65269babd1 129 SUPERFAMILY SSF51316 5 128 1.83E-56 T 22-04-2016 IPR011057 Mss4-like MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 16 32 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 SUPERFAMILY SSF51569 4 294 1.21E-95 T 22-04-2016 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 Gene3D G3DSA:3.20.20.70 3 350 6.2E-142 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 Pfam PF00682 HMGL-like 8 276 1.6E-91 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 PANTHER PTHR10277 7 384 4.3E-198 T 22-04-2016 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 203 216 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 MED134_RS11805 d0bc94e5938dd0c301c45490c446b28e 393 PANTHER PTHR10277:SF9 7 384 4.3E-198 T 22-04-2016 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 PANTHER PTHR32322:SF8 1 290 7.8E-54 T 22-04-2016 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 SUPERFAMILY SSF103481 195 292 2.48E-13 T 22-04-2016 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 SUPERFAMILY SSF103481 41 142 3.53E-11 T 22-04-2016 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 PANTHER PTHR32322 1 290 7.8E-54 T 22-04-2016 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 Pfam PF00892 EamA-like transporter family 9 140 1.7E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS01535 02e0d4a6384747d04d7ed8d212276b9e 309 Pfam PF00892 EamA-like transporter family 153 290 6.3E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 22 158 3.6E-43 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 Gene3D G3DSA:3.40.50.960 16 163 7.2E-54 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 PANTHER PTHR21058 18 164 1.4E-53 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 22 160 4.4E-51 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 SUPERFAMILY SSF52121 16 162 3.92E-48 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS05425 eefc48df689049945ab16d8e94e6feaf 165 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 17 163 25.543 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS02775 b8a8de92e7f1c08da2ac553aa56ce2df 327 Pfam PF01944 Stage II sporulation protein M 103 281 2.1E-34 T 22-04-2016 IPR002798 Stage II sporulation protein M-like MED134_RS02775 b8a8de92e7f1c08da2ac553aa56ce2df 327 PANTHER PTHR35337 12 311 3.4E-44 T 22-04-2016 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 96 125 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 130 159 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 247 276 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 213 241 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 168 197 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PRINTS PR00142 RecA protein signature 301 318 3.0E-81 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 SUPERFAMILY SSF54752 272 328 4.58E-19 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 SUPERFAMILY SSF52540 10 271 1.41E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 Pfam PF00154 recA bacterial DNA recombination protein 10 272 2.2E-141 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PANTHER PTHR22942 1 335 1.2E-188 T 22-04-2016 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 PANTHER PTHR22942:SF1 1 335 1.2E-188 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 ProSitePatterns PS00321 recA signature. 216 224 - T 22-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 Hamap MF_00268 Protein RecA [recA]. 8 333 51.073 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 Gene3D G3DSA:3.30.250.10 272 329 1.1E-24 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 SMART SM00382 60 231 7.0E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 Gene3D G3DSA:3.40.50.300 32 271 3.9E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08800 ed1ce91cfa2de14f4279c5f05c1ab2b8 335 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 8 327 6.7E-170 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MED134_RS01090 329b921b2dc699daa4e98033fdbecdb5 288 PANTHER PTHR10277:SF1 1 256 7.9E-85 T 22-04-2016 MED134_RS01090 329b921b2dc699daa4e98033fdbecdb5 288 Pfam PF00682 HMGL-like 11 274 6.5E-24 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 MED134_RS01090 329b921b2dc699daa4e98033fdbecdb5 288 Gene3D G3DSA:3.20.20.70 3 269 3.9E-44 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS01090 329b921b2dc699daa4e98033fdbecdb5 288 PANTHER PTHR10277 1 256 7.9E-85 T 22-04-2016 MED134_RS01090 329b921b2dc699daa4e98033fdbecdb5 288 SUPERFAMILY SSF51569 2 282 6.78E-45 T 22-04-2016 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 9.0E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 9.0E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 9.0E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 Gene3D G3DSA:1.10.10.10 1 52 1.7E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 SUPERFAMILY SSF54909 65 149 2.41E-22 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 Gene3D G3DSA:3.30.70.920 56 139 3.9E-29 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 PANTHER PTHR30154:SF28 1 150 1.3E-56 T 22-04-2016 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 SMART SM00344 3 112 8.4E-43 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 8.3E-17 T 22-04-2016 MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 SUPERFAMILY SSF46785 2 62 1.05E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 8.6E-24 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS04140 05e8a2762691d915bcdbf6b4443999b5 152 PANTHER PTHR30154 1 150 1.3E-56 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 Pfam PF02926 THUMP domain 19 150 8.1E-12 T 22-04-2016 IPR004114 THUMP domain GO:0003723 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 PANTHER PTHR14911 248 367 2.8E-62 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 PANTHER PTHR14911 1 209 2.8E-62 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 SMART SM00981 53 151 6.1E-18 T 22-04-2016 IPR004114 THUMP domain GO:0003723 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 Gene3D G3DSA:3.40.50.150 146 211 1.8E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 Gene3D G3DSA:3.40.50.150 248 359 1.8E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 PANTHER PTHR14911:SF13 248 367 2.8E-62 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 PANTHER PTHR14911:SF13 1 209 2.8E-62 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 SUPERFAMILY SSF143437 9 149 6.63E-5 T 22-04-2016 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 SUPERFAMILY SSF53335 251 368 6.3E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 SUPERFAMILY SSF53335 137 214 6.3E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 Pfam PF01170 Putative RNA methylase family UPF0020 159 363 1.1E-39 T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS13850 73cbcff1a71b833fab446a67f8baa659 382 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 192 203 - T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS04680 9789ad863f8c6edf4ad27369361b061d 226 Pfam PF13505 Outer membrane protein beta-barrel domain 74 222 1.5E-8 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel MED134_RS04680 9789ad863f8c6edf4ad27369361b061d 226 Gene3D G3DSA:2.40.160.20 79 215 8.5E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04680 9789ad863f8c6edf4ad27369361b061d 226 SUPERFAMILY SSF56925 81 214 4.71E-6 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 Pfam PF01165 Ribosomal protein S21 4 53 9.1E-18 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 17.393 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 6.2E-6 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 6.2E-6 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 6.2E-6 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 6.2E-6 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 22-04-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS04960 adf28fc7cb6c895b1a282bd58393a62e 64 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 53 1.1E-16 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 SMART SM00849 77 281 1.1E-11 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 SUPERFAMILY SSF56281 79 282 3.93E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 Gene3D G3DSA:3.60.15.10 78 283 7.2E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 PANTHER PTHR23200 71 284 3.8E-36 T 22-04-2016 MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 PANTHER PTHR23200:SF45 71 284 3.8E-36 T 22-04-2016 MED134_RS10885 8ca5e036218599c7d74f1d1109a6edda 294 Pfam PF00753 Metallo-beta-lactamase superfamily 81 281 2.6E-18 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 PANTHER PTHR11019:SF50 50 303 6.1E-36 T 22-04-2016 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 SMART SM00342 214 297 3.1E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 PANTHER PTHR11019 50 303 6.1E-36 T 22-04-2016 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 Gene3D G3DSA:1.10.10.60 215 248 5.4E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 Pfam PF12833 Helix-turn-helix domain 220 298 6.7E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 Gene3D G3DSA:1.10.10.60 252 300 3.9E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 281 3.2E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 297 3.2E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS14410 e4cee3147fbc6e5f7964d0cef4cce96d 303 SUPERFAMILY SSF46689 252 300 1.52E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 TIGRFAM TIGR03525 GldK: gliding motility-associated lipoprotein GldK 1 450 4.5E-255 T 22-04-2016 IPR019866 Gliding motility-associated lipoprotein GldK MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 SUPERFAMILY SSF56436 38 90 2.94E-65 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 SUPERFAMILY SSF56436 217 444 2.94E-65 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 Pfam PF03781 Sulfatase-modifying factor enzyme 1 41 442 7.4E-50 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 PANTHER PTHR23150 301 455 5.0E-40 T 22-04-2016 MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 PANTHER PTHR23150 253 282 5.0E-40 T 22-04-2016 MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 PANTHER PTHR23150 32 116 5.0E-40 T 22-04-2016 MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 Gene3D G3DSA:3.90.1580.10 219 445 9.2E-91 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS06100 314f74efe4337ee92e5d496ed48c9f57 459 Gene3D G3DSA:3.90.1580.10 32 92 9.2E-91 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 365 4.4E-72 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 PANTHER PTHR21499:SF3 3 352 4.5E-71 T 22-04-2016 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 Pfam PF00696 Amino acid kinase family 2 276 1.4E-40 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 SUPERFAMILY SSF55021 297 383 2.0E-12 T 22-04-2016 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 PANTHER PTHR21499 3 352 4.5E-71 T 22-04-2016 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 SUPERFAMILY SSF53633 1 288 2.62E-69 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 Gene3D G3DSA:3.40.1160.10 105 289 1.1E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS08195 cc062f8ee4f10e78ae6bd07a217f5a9a 416 Gene3D G3DSA:3.40.1160.10 1 48 1.1E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS07325 2b728b25b65e8c378afe2aafc3d54b8e 1797 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1408 1420 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS07325 2b728b25b65e8c378afe2aafc3d54b8e 1797 SUPERFAMILY SSF47473 1365 1504 2.66E-5 T 22-04-2016 IPR011992 EF-hand domain pair MED134_RS07325 2b728b25b65e8c378afe2aafc3d54b8e 1797 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 1703 1793 8.7E-11 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS07325 2b728b25b65e8c378afe2aafc3d54b8e 1797 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1676 1688 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS07325 2b728b25b65e8c378afe2aafc3d54b8e 1797 Pfam PF13585 C-terminal domain of CHU protein family 1700 1786 4.2E-23 T 22-04-2016 MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 PANTHER PTHR11274 12 199 7.8E-16 T 22-04-2016 MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 SUPERFAMILY SSF52540 30 170 3.34E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 SUPERFAMILY SSF52540 429 549 3.34E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 SMART SM00487 8 199 2.6E-17 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 Gene3D G3DSA:3.40.50.300 7 174 1.7E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 Gene3D G3DSA:3.40.50.300 451 547 6.5E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08705 af05b72ffe142d8b2ddcf86aaf254dab 886 Pfam PF04851 Type III restriction enzyme, res subunit 11 168 3.2E-19 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 Gene3D G3DSA:3.40.50.1770 198 353 1.1E-23 T 22-04-2016 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 SMART SM01003 4 137 1.8E-69 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 Gene3D G3DSA:3.40.50.1770 1 176 2.8E-59 T 22-04-2016 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 SUPERFAMILY SSF52283 305 359 8.42E-61 T 22-04-2016 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 SUPERFAMILY SSF52283 1 137 8.42E-61 T 22-04-2016 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 SUPERFAMILY SSF51735 137 303 2.73E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.9E-43 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 6.5E-85 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 SMART SM01002 149 297 2.9E-87 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 365 1.7E-157 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 PANTHER PTHR10160 1 367 4.2E-198 T 22-04-2016 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 22-04-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 22-04-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 Gene3D G3DSA:3.50.50.60 177 197 5.8E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10135 d9dd56d9fb57041b17144a6459b03c02 368 PIRSF PIRSF000183 1 367 3.3E-158 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Pfam PF00175 Oxidoreductase NAD-binding domain 296 416 3.5E-13 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 SUPERFAMILY SSF52343 275 431 2.62E-32 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 12 435 6.1E-170 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PIRSF PIRSF000044 5 435 4.9E-175 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Gene3D G3DSA:3.40.50.80 295 418 9.2E-35 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 44 121 1.9E-11 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Pfam PF00970 Oxidoreductase FAD-binding domain 216 284 2.0E-5 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Gene3D G3DSA:3.10.20.30 45 129 5.2E-21 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PANTHER PTHR19370:SF32 218 435 2.2E-116 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PANTHER PTHR19370:SF32 67 180 2.2E-116 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Gene3D G3DSA:2.40.30.10 130 282 1.1E-56 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 SUPERFAMILY SSF63380 111 183 6.35E-35 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 SUPERFAMILY SSF63380 216 288 6.35E-35 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PANTHER PTHR19370 218 435 2.2E-116 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PANTHER PTHR19370 67 180 2.2E-116 T 22-04-2016 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 SUPERFAMILY SSF54292 44 130 2.2E-21 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 9 435 63.028 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 222 229 6.97E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 260 269 6.97E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 294 313 6.97E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS07015 75dab0122692e6a8ff06c01d8ea01dad 435 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 401 409 6.97E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Pfam PF02503 Polyphosphate kinase middle domain 124 323 1.9E-43 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 SUPERFAMILY SSF56024 503 686 1.68E-68 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Pfam PF13089 Polyphosphate kinase N-terminal domain 9 114 1.2E-33 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 PANTHER PTHR30218 6 686 2.0E-266 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Gene3D G3DSA:3.30.1840.10 111 304 4.4E-44 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 SUPERFAMILY SSF140356 6 111 1.83E-33 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 PANTHER PTHR30218:SF0 6 686 2.0E-266 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 PIRSF PIRSF015589 1 687 1.3E-225 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 SUPERFAMILY SSF143724 116 317 1.51E-48 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Gene3D G3DSA:3.30.870.10 320 502 9.0E-64 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 8 669 8.1E-222 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 SUPERFAMILY SSF56024 319 492 2.3E-50 T 22-04-2016 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Pfam PF13090 Polyphosphate kinase C-terminal domain 334 666 1.1E-138 T 22-04-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MED134_RS01005 588fe3bec052e159ea107f936268268e 688 Gene3D G3DSA:3.30.870.10 503 684 9.0E-66 T 22-04-2016 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 PANTHER PTHR11138 4 315 8.3E-92 T 22-04-2016 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 SUPERFAMILY SSF50486 208 310 7.85E-23 T 22-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 Gene3D G3DSA:3.10.25.10 210 314 1.3E-25 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 Pfam PF02911 Formyl transferase, C-terminal domain 206 307 3.5E-23 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 Pfam PF00551 Formyl transferase 5 181 2.0E-36 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 4 310 32.388 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 Gene3D G3DSA:3.40.50.170 3 199 2.4E-63 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 4 308 1.1E-77 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS13985 a816500cde5b1a14dcb0de4d30c07715 316 SUPERFAMILY SSF53328 2 198 1.44E-58 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS12115 f080ed07e289333a0411b8066b34eea9 501 SUPERFAMILY SSF56925 373 501 4.97E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Gene3D G3DSA:3.30.499.10 318 490 8.5E-51 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 131 139 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 415 428 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 227 240 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 165 180 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 321 335 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 241 254 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 151 164 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PRINTS PR00415 Aconitase family signature 356 367 5.8E-34 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Gene3D G3DSA:3.40.1060.10 198 316 4.5E-38 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Gene3D G3DSA:3.30.499.10 10 196 1.5E-67 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 ProSitePatterns PS00450 Aconitase family signature 1. 352 368 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Pfam PF00694 Aconitase C-terminal domain 558 687 6.5E-42 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PANTHER PTHR11670 12 757 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Pfam PF00330 Aconitase family (aconitate hydratase) 34 479 5.2E-151 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 SUPERFAMILY SSF53732 6 526 1.22E-148 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 SUPERFAMILY SSF52016 533 754 1.41E-60 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 PANTHER PTHR11670:SF30 12 757 0.0 T 22-04-2016 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 TIGRFAM TIGR01340 aconitase_mito: aconitate hydratase, mitochondrial 12 751 0.0 T 22-04-2016 IPR006248 Aconitase, mitochondrial-like GO:0003994|GO:0006099|GO:0051539 MED134_RS00865 6ad3edf09b09b99ee18ce1cb99cf2137 757 Gene3D G3DSA:3.20.19.10 538 754 2.1E-75 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 39 255 1.3E-51 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 SMART SM00646 98 255 2.3E-29 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 SUPERFAMILY SSF53187 182 259 7.85E-49 T 22-04-2016 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 SUPERFAMILY SSF53187 37 133 7.85E-49 T 22-04-2016 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 PANTHER PTHR30404:SF0 30 289 3.8E-59 T 22-04-2016 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 Gene3D G3DSA:3.40.630.40 183 258 1.7E-58 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 Gene3D G3DSA:3.40.630.40 37 136 1.7E-58 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 MED134_RS03615 7549f99086d82ec2304baf5ad23134cc 373 PANTHER PTHR30404 30 289 3.8E-59 T 22-04-2016 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 PANTHER PTHR18901 4 217 1.3E-54 T 22-04-2016 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 187 4.4E-27 T 22-04-2016 IPR023214 HAD-like domain MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 Gene3D G3DSA:3.40.50.1000 94 209 4.9E-33 T 22-04-2016 IPR023214 HAD-like domain MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 Gene3D G3DSA:3.40.50.1000 3 16 4.9E-33 T 22-04-2016 IPR023214 HAD-like domain MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 188 5.5E-15 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 Gene3D G3DSA:1.10.150.240 17 92 5.1E-24 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 PANTHER PTHR18901:SF19 4 217 1.3E-54 T 22-04-2016 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 4 188 1.1E-54 T 22-04-2016 IPR010976 Beta-phosphoglucomutase hydrolase MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 4 189 5.5E-65 T 22-04-2016 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-6317|MetaCyc: PWY-7459 MED134_RS10605 d4159c363a848c28da6d8ba83409178b 218 SUPERFAMILY SSF56784 3 209 3.54E-46 T 22-04-2016 IPR023214 HAD-like domain MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 322 340 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 198 216 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 226 245 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 426 446 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 99 121 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PRINTS PR00175 Sodium/alanine symporter signature 367 389 6.0E-40 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PANTHER PTHR30330 8 460 4.0E-149 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 PANTHER PTHR30330:SF3 8 460 4.0E-149 T 22-04-2016 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 Pfam PF01235 Sodium:alanine symporter family 64 460 5.4E-123 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 TIGRFAM TIGR00835 agcS: amino acid carrier protein 23 457 1.4E-120 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04815 c623724d7312a8263af3d59cff79a3fc 462 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 99 114 - T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Gene3D G3DSA:3.30.70.100 82 155 1.4E-8 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF81665 299 326 1.57E-7 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF81665 417 508 1.57E-7 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF81665 750 776 1.57E-7 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00943 Copper-transporting ATPase signature 678 695 5.6E-11 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00943 Copper-transporting ATPase signature 497 512 5.6E-11 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00943 Copper-transporting ATPase signature 220 239 5.6E-11 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00943 Copper-transporting ATPase signature 126 146 5.6E-11 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00943 Copper-transporting ATPase signature 439 453 5.6E-11 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PANTHER PTHR24093 74 296 9.9E-108 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PANTHER PTHR24093 323 798 9.9E-108 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 647 657 1.2E-13 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 514 528 1.2E-13 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 366 380 1.2E-13 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 701 720 1.2E-13 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Gene3D G3DSA:3.40.50.1000 631 746 3.0E-25 T 22-04-2016 IPR023214 HAD-like domain MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Gene3D G3DSA:3.40.50.1000 498 528 3.0E-25 T 22-04-2016 IPR023214 HAD-like domain MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Gene3D G3DSA:2.70.150.10 269 412 2.1E-15 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Pfam PF00122 E1-E2 ATPase 300 505 1.6E-38 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 300 787 9.7E-55 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF56784 567 797 1.61E-26 T 22-04-2016 IPR023214 HAD-like domain MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF56784 512 532 1.61E-26 T 22-04-2016 IPR023214 HAD-like domain MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF81653 332 413 2.75E-14 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PANTHER PTHR24093:SF50 74 296 9.9E-108 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 PANTHER PTHR24093:SF50 323 798 9.9E-108 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 516 522 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 3 54 1.2E-10 T 22-04-2016 IPR021993 Putative metal-binding domain of cation transport ATPase MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 Pfam PF00702 haloacid dehalogenase-like hydrolase 510 715 4.0E-23 T 22-04-2016 MED134_RS04605 97c72d13a84c5dd4175e637be9b8da1d 814 SUPERFAMILY SSF55008 78 147 1.57E-11 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS09740 1f3dca427857102ac8559c97963af986 133 Gene3D G3DSA:3.30.160.200 8 103 5.2E-22 T 22-04-2016 MED134_RS09740 1f3dca427857102ac8559c97963af986 133 PANTHER PTHR11075 9 126 6.0E-18 T 22-04-2016 MED134_RS09740 1f3dca427857102ac8559c97963af986 133 Pfam PF00472 RF-1 domain 8 128 4.5E-17 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MED134_RS09740 1f3dca427857102ac8559c97963af986 133 SUPERFAMILY SSF110916 7 89 4.32E-8 T 22-04-2016 MED134_RS13725 8a65d7f35081d9c94db2d02c36b7cfdf 206 SUPERFAMILY SSF54211 15 136 8.34E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS13725 8a65d7f35081d9c94db2d02c36b7cfdf 206 Gene3D G3DSA:3.30.230.30 15 137 3.9E-43 T 22-04-2016 IPR001498 Impact, N-terminal MED134_RS13725 8a65d7f35081d9c94db2d02c36b7cfdf 206 Pfam PF01205 Uncharacterized protein family UPF0029 24 129 1.4E-30 T 22-04-2016 IPR001498 Impact, N-terminal MED134_RS13725 8a65d7f35081d9c94db2d02c36b7cfdf 206 Gene3D G3DSA:3.30.70.240 142 193 5.1E-4 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS13725 8a65d7f35081d9c94db2d02c36b7cfdf 206 PANTHER PTHR16301 21 196 3.9E-51 T 22-04-2016 IPR023582 Impact family MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.30.1490.110 97 167 9.5E-15 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 SUPERFAMILY SSF53067 5 220 1.73E-48 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 PANTHER PTHR32432 1 434 2.9E-116 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 449 28.12 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 PANTHER PTHR32432:SF4 1 434 2.9E-116 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 SUPERFAMILY SSF53067 199 381 1.87E-39 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 380 2.7E-110 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Pfam PF02491 SHS2 domain inserted in FTSA 82 160 2.6E-24 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.90.640.10 234 296 2.2E-16 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 PIRSF PIRSF003101 1 445 2.4E-130 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.30.420.40 209 233 3.8E-29 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.30.420.40 297 354 3.8E-29 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 SMART SM00842 7 195 1.3E-79 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Pfam PF14450 Cell division protein FtsA 8 192 6.6E-9 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Pfam PF14450 Cell division protein FtsA 206 378 6.1E-23 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.30.420.40 1 96 1.1E-24 T 22-04-2016 MED134_RS12545 dfba5e455da06137bf6ed9aa53ffde25 449 Gene3D G3DSA:3.30.420.40 168 208 1.1E-24 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 1.6E-64 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PIRSF PIRSF000350 1 457 1.3E-80 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 Gene3D G3DSA:3.50.50.60 136 325 2.2E-55 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 1.1E-34 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 SUPERFAMILY SSF55424 335 457 7.73E-38 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PANTHER PTHR22912 1 451 2.7E-197 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 Gene3D G3DSA:3.30.390.30 326 457 6.0E-47 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PANTHER PTHR22912:SF125 1 451 2.7E-197 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 Gene3D G3DSA:3.50.50.60 2 135 2.2E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 319 3.9E-69 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 SUPERFAMILY SSF51905 2 365 1.59E-70 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 3.4E-174 T 22-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.7E-35 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.7E-35 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 1.7E-35 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 1.7E-35 T 22-04-2016 MED134_RS04490 f359946cc67a1d2ce4a7be6b915ab074 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 1.7E-35 T 22-04-2016 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 Gene3D G3DSA:1.10.560.10 3 186 2.6E-44 T 22-04-2016 IPR027413 GroEL-like equatorial domain MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 Gene3D G3DSA:1.10.560.10 366 518 3.1E-43 T 22-04-2016 IPR027413 GroEL-like equatorial domain MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 Gene3D G3DSA:3.50.7.10 187 365 8.6E-101 T 22-04-2016 IPR027409 GroEL-like apical domain MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 SUPERFAMILY SSF52029 184 376 5.23E-86 T 22-04-2016 IPR027409 GroEL-like apical domain MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 SUPERFAMILY SSF54849 140 205 2.2E-20 T 22-04-2016 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 4.0E-259 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 41.888 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PRINTS PR00298 60kDa chaperonin signature 268 291 1.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PRINTS PR00298 60kDa chaperonin signature 398 419 1.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PRINTS PR00298 60kDa chaperonin signature 350 375 1.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 SUPERFAMILY SSF48592 6 133 3.16E-76 T 22-04-2016 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 SUPERFAMILY SSF48592 406 520 3.16E-76 T 22-04-2016 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 22-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 PANTHER PTHR11353 1 544 1.4E-246 T 22-04-2016 MED134_RS06155 dd9ca1795f038ed63790ad42c97f636a 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 1.8E-97 T 22-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 Gene3D G3DSA:1.10.260.40 12 71 2.6E-10 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 Gene3D G3DSA:2.10.109.10 101 212 8.2E-13 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 SUPERFAMILY SSF51306 103 212 4.45E-13 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 Pfam PF01381 Helix-turn-helix 14 66 1.1E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 SMART SM00530 12 66 1.4E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 SUPERFAMILY SSF47413 11 71 1.88E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS07285 7dd30e2557810577415ffb5b37248a7b 256 Pfam PF00717 Peptidase S24-like 140 207 5.4E-6 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B MED134_RS06270 9db483c310e601efce590a2760d29632 406 Hamap MF_01113 DNA polymerase IV [dinB]. 2 347 30.695 T 22-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06270 9db483c310e601efce590a2760d29632 406 Pfam PF00817 impB/mucB/samB family 9 152 1.2E-42 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06270 9db483c310e601efce590a2760d29632 406 Gene3D G3DSA:3.30.70.270 66 160 4.6E-22 T 22-04-2016 MED134_RS06270 9db483c310e601efce590a2760d29632 406 PANTHER PTHR11076 1 340 6.6E-101 T 22-04-2016 MED134_RS06270 9db483c310e601efce590a2760d29632 406 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 340 7.1E-19 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06270 9db483c310e601efce590a2760d29632 406 SUPERFAMILY SSF100879 237 337 3.3E-23 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06270 9db483c310e601efce590a2760d29632 406 Gene3D G3DSA:1.10.150.20 164 235 2.3E-16 T 22-04-2016 MED134_RS06270 9db483c310e601efce590a2760d29632 406 SUPERFAMILY SSF56672 1 232 1.69E-67 T 22-04-2016 MED134_RS06270 9db483c310e601efce590a2760d29632 406 Gene3D G3DSA:3.30.1490.100 240 342 5.2E-22 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 PANTHER PTHR30121 11 465 3.7E-141 T 22-04-2016 MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 PANTHER PTHR30121:SF3 11 465 3.7E-141 T 22-04-2016 MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 Gene3D G3DSA:3.40.50.300 228 397 4.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 Gene3D G3DSA:3.40.50.300 25 111 4.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 Pfam PF05872 Bacterial protein of unknown function (DUF853) 34 480 3.8E-171 T 22-04-2016 IPR033186 Helicase HerA-like C-terminal MED134_RS02400 cccbb170d1867ff9a3be461ee70d0334 511 SUPERFAMILY SSF52540 30 405 6.45E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04715 c215d35537abeeda49f6cbf2139040e0 473 SUPERFAMILY SSF53448 103 396 1.03E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04715 c215d35537abeeda49f6cbf2139040e0 473 Pfam PF13641 Glycosyltransferase like family 2 114 349 2.4E-28 T 22-04-2016 MED134_RS04715 c215d35537abeeda49f6cbf2139040e0 473 Gene3D G3DSA:3.90.550.10 116 358 9.7E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04715 c215d35537abeeda49f6cbf2139040e0 473 PANTHER PTHR22913 176 362 3.7E-44 T 22-04-2016 IPR026107 Hyaluronan synthase/nodulation protein C MED134_RS04715 c215d35537abeeda49f6cbf2139040e0 473 PANTHER PTHR22913:SF12 176 362 3.7E-44 T 22-04-2016 MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 Pfam PF02719 Polysaccharide biosynthesis protein 308 597 1.4E-121 T 22-04-2016 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 Gene3D G3DSA:3.90.25.10 493 574 4.1E-9 T 22-04-2016 MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 PANTHER PTHR10366 307 587 4.1E-120 T 22-04-2016 MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 Gene3D G3DSA:3.40.50.720 306 492 8.1E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 PANTHER PTHR10366:SF256 307 587 4.1E-120 T 22-04-2016 MED134_RS01435 4bed89cedea6878a93a9613dae3a88f7 668 SUPERFAMILY SSF51735 305 576 2.09E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Pfam PF00593 TonB dependent receptor 531 796 8.0E-10 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 SUPERFAMILY SSF56935 526 798 5.04E-70 T 22-04-2016 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 SUPERFAMILY SSF56935 108 487 5.04E-70 T 22-04-2016 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Gene3D G3DSA:2.170.130.10 90 221 5.5E-18 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Gene3D G3DSA:2.60.40.1120 24 89 1.4E-13 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 SUPERFAMILY SSF49464 23 108 1.16E-16 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Pfam PF13715 CarboxypepD_reg-like domain 25 103 1.4E-13 T 22-04-2016 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Pfam PF07715 TonB-dependent Receptor Plug Domain 121 221 8.3E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Gene3D G3DSA:2.40.170.20 299 797 8.6E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 Gene3D G3DSA:2.40.170.20 222 267 8.6E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 PANTHER PTHR30069 1 224 1.5E-19 T 22-04-2016 MED134_RS03010 7636994c05a3cd943ccde79b73994bb6 798 PANTHER PTHR30069:SF2 1 224 1.5E-19 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PRINTS PR00315 GTP-binding elongation factor signature 6 19 6.9E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PRINTS PR00315 GTP-binding elongation factor signature 89 100 6.9E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PRINTS PR00315 GTP-binding elongation factor signature 49 57 6.9E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PRINTS PR00315 GTP-binding elongation factor signature 73 83 6.9E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PRINTS PR00315 GTP-binding elongation factor signature 125 134 6.9E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Pfam PF03144 Elongation factor Tu domain 2 207 274 4.4E-9 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Gene3D G3DSA:3.40.50.300 2 191 1.7E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 172 2.0E-21 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 TIGRFAM TIGR01393 lepA: elongation factor 4 2 596 1.1E-296 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 SUPERFAMILY SSF50447 164 286 2.83E-28 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PANTHER PTHR23115:SF175 398 597 3.8E-277 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PANTHER PTHR23115:SF175 2 372 3.8E-277 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Gene3D G3DSA:2.40.30.10 192 288 6.2E-23 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Pfam PF00009 Elongation factor Tu GTP binding domain 2 180 5.2E-55 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PANTHER PTHR23115 398 597 3.8E-277 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 PANTHER PTHR23115 2 372 3.8E-277 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 SUPERFAMILY SSF52540 2 200 2.06E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 SUPERFAMILY SSF54980 291 369 3.96E-19 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 SUPERFAMILY SSF54980 400 495 9.59E-21 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 598 285.268 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Gene3D G3DSA:3.30.70.240 402 491 4.4E-18 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Pfam PF00679 Elongation factor G C-terminus 400 486 3.8E-19 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Gene3D G3DSA:3.30.70.870 290 367 4.7E-26 T 22-04-2016 MED134_RS06750 481eea1cddac9cb27e87d524a4383a30 598 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 4.5E-51 T 22-04-2016 IPR013842 GTP-binding protein LepA, C-terminal MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 Gene3D G3DSA:3.30.230.10 19 202 1.1E-53 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 PANTHER PTHR10977:SF3 6 336 1.7E-43 T 22-04-2016 MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 PANTHER PTHR10977 6 336 1.7E-43 T 22-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 SUPERFAMILY SSF55060 211 338 1.06E-19 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 Gene3D G3DSA:3.30.70.890 203 358 1.8E-37 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 SUPERFAMILY SSF54211 19 180 1.37E-21 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS10675 d985bd208fadc241f82af15c882075b2 360 PIRSF PIRSF015950 14 360 2.3E-66 T 22-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 SUPERFAMILY SSF51905 4 326 6.49E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 287 1.5E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.2E-20 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.2E-20 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.2E-20 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.2E-20 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.2E-20 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 8.6E-10 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 8.6E-10 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 8.6E-10 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 PANTHER PTHR22912 5 338 2.6E-61 T 22-04-2016 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 Gene3D G3DSA:3.50.50.60 1 101 5.3E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06655 c107e4430391a1cc26b0ad62b5059b39 446 Gene3D G3DSA:3.50.50.60 102 312 1.8E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10045 b92d6d1391b160060307f810d770ae29 186 PANTHER PTHR37512 14 185 3.9E-40 T 22-04-2016 MED134_RS10045 b92d6d1391b160060307f810d770ae29 186 SUPERFAMILY SSF52540 12 181 5.16E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10045 b92d6d1391b160060307f810d770ae29 186 Gene3D G3DSA:3.40.50.300 13 177 1.8E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10045 b92d6d1391b160060307f810d770ae29 186 Pfam PF13521 AAA domain 14 173 1.1E-37 T 22-04-2016 MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 SUPERFAMILY SSF52283 1 131 5.86E-30 T 22-04-2016 MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 Gene3D G3DSA:3.40.50.720 1 108 7.7E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 292 2.2E-49 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 Gene3D G3DSA:3.40.50.720 109 292 5.4E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 SUPERFAMILY SSF51735 97 293 2.37E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 PANTHER PTHR10996 1 262 3.0E-82 T 22-04-2016 MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 PANTHER PTHR10996 278 312 3.0E-82 T 22-04-2016 MED134_RS08240 ddad6523321cdc19f5e445e5368dad70 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 312 1.2E-20 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Pfam PF00342 Phosphoglucose isomerase 50 531 8.3E-214 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 488 505 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PANTHER PTHR11469 1 535 1.4E-294 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Gene3D G3DSA:1.10.1390.10 493 535 1.8E-18 T 22-04-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 SUPERFAMILY SSF53697 5 535 2.03E-202 T 22-04-2016 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Gene3D G3DSA:3.40.50.10490 4 100 2.9E-164 T 22-04-2016 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Gene3D G3DSA:3.40.50.10490 254 492 2.9E-164 T 22-04-2016 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Gene3D G3DSA:3.40.50.10490 139 176 2.9E-164 T 22-04-2016 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PANTHER PTHR11469:SF4 1 535 1.4E-294 T 22-04-2016 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 44 515 40.672 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 142 161 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 252 270 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 488 501 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 474 488 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 329 350 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 PRINTS PR00662 Glucose-6-phosphate isomerase signature 456 474 4.0E-51 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS07725 4322faac24c56bdab1c5381484724ba0 536 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 256 269 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS00200 cb7b8117746c280374a99e44626341cd 138 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 28 131 1.2E-27 T 22-04-2016 IPR018673 Protein of unknown function DUF2141 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 10 348 2.3E-104 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 Pfam PF01761 3-dehydroquinate synthase 62 319 1.8E-87 T 22-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 SUPERFAMILY SSF56796 3 350 2.22E-87 T 22-04-2016 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 Gene3D G3DSA:1.20.1090.10 168 350 1.6E-53 T 22-04-2016 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 PIRSF PIRSF001455 1 357 5.1E-106 T 22-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 Gene3D G3DSA:3.40.50.1970 4 167 5.6E-52 T 22-04-2016 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 7 352 33.496 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 MED134_RS14545 f2f1c58b415bad0ee5dd3ee79b813240 362 PANTHER PTHR21090 1 355 1.1E-114 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PANTHER PTHR22939:SF79 61 433 3.0E-102 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Gene3D G3DSA:2.40.10.10 54 170 6.2E-32 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Gene3D G3DSA:2.30.42.10 382 459 5.3E-5 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Pfam PF13180 PDZ domain 299 372 7.3E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Pfam PF13365 Trypsin-like peptidase domain 106 242 1.4E-33 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PANTHER PTHR22939 61 433 3.0E-102 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 SUPERFAMILY SSF50494 61 277 2.73E-60 T 22-04-2016 IPR009003 Peptidase S1, PA clan MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Gene3D G3DSA:2.40.10.10 171 283 5.9E-42 T 22-04-2016 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 SMART SM00228 381 459 12.0 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 SMART SM00228 281 363 3.5E-4 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 Gene3D G3DSA:2.30.42.10 284 372 1.6E-20 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 SUPERFAMILY SSF50156 265 372 2.29E-17 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 321 333 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 136 156 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 177 201 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 115 127 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 235 252 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS04000 9418d33cf1e3e500bb67830e0a6c5e42 468 PRINTS PR00834 HtrA/DegQ protease family signature 213 230 7.1E-50 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 Pfam PF01513 ATP-NAD kinase 16 272 6.0E-53 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 SUPERFAMILY SSF111331 2 291 1.24E-75 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 Hamap MF_00361 NAD kinase [nadK]. 1 288 29.973 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 Gene3D G3DSA:3.40.50.10330 1 151 4.3E-34 T 22-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 Gene3D G3DSA:2.60.200.30 152 263 4.4E-39 T 22-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 MED134_RS07515 0f66a962daa70fee4668aefbf2bbe316 294 PANTHER PTHR20275 1 294 6.3E-80 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF02128 Fungalysin metallopeptidase (M36) 244 606 1.8E-145 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 1248 1317 3.8E-15 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 374 394 6.3E-10 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 572 594 6.3E-10 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 PANTHER PTHR33478 140 634 3.0E-126 T 22-04-2016 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF00041 Fibronectin type III domain 812 883 6.1E-8 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SUPERFAMILY SSF55486 271 603 5.13E-60 T 22-04-2016 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SMART SM00060 810 883 1.8E-12 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SUPERFAMILY SSF49899 644 801 8.55E-31 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SUPERFAMILY SSF49899 910 1071 4.27E-32 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF03413 Peptidase propeptide and YPEB domain 111 199 1.3E-4 T 22-04-2016 IPR025711 PepSY domain MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SMART SM00137 908 1074 8.4E-7 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SMART SM00137 643 805 7.8E-9 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Gene3D G3DSA:2.60.40.10 808 894 6.8E-23 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 61 90 1.7E-6 T 22-04-2016 IPR011096 FTP domain MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 SUPERFAMILY SSF49265 808 894 1.43E-16 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF00629 MAM domain, meprin/A5/mu 914 1069 1.5E-25 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS14740 c744ea687c33b6d736aa028b20d1ae11 1317 Pfam PF00629 MAM domain, meprin/A5/mu 650 800 1.6E-25 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Pfam PF02080 TrkA-C domain 281 338 3.3E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 SUPERFAMILY SSF51735 109 252 3.1E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Gene3D G3DSA:3.40.50.720 110 252 1.5E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Gene3D G3DSA:3.30.70.1450 280 336 9.5E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Gene3D G3DSA:1.10.287.70 9 93 7.4E-19 T 22-04-2016 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 PANTHER PTHR16254 11 275 6.4E-74 T 22-04-2016 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Pfam PF02254 TrkA-N domain 114 230 3.8E-32 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 Pfam PF07885 Ion channel 16 89 5.2E-14 T 22-04-2016 IPR013099 Potassium channel domain MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 PANTHER PTHR16254:SF21 11 275 6.4E-74 T 22-04-2016 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 SUPERFAMILY SSF81324 7 134 2.35E-26 T 22-04-2016 MED134_RS04980 81f1f73339d3d3c9264f6a431b5fef85 339 SUPERFAMILY SSF116726 281 338 7.59E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 TIGRFAM TIGR00576 dut: dUTP diphosphatase 8 142 1.1E-54 T 22-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 SUPERFAMILY SSF51283 8 143 2.22E-50 T 22-04-2016 IPR029054 dUTPase-like MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 1 143 32.446 T 22-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 Pfam PF00692 dUTPase 12 142 5.4E-32 T 22-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 Gene3D G3DSA:2.70.40.10 3 143 1.3E-54 T 22-04-2016 IPR029054 dUTPase-like MED134_RS09450 8bb51b8477cb5c883ca8126e9a9ab84b 144 PANTHER PTHR11241 1 143 1.5E-56 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PANTHER PTHR10366 71 334 7.0E-165 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PANTHER PTHR10366 2 53 7.0E-165 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 Gene3D G3DSA:3.90.25.10 215 330 1.5E-18 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 9.7E-20 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PRINTS PR01713 Nucleotide sugar epimerase signature 232 247 9.7E-20 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 9.7E-20 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 9.7E-20 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 SUPERFAMILY SSF51735 1 331 3.82E-90 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 262 2.5E-58 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PANTHER PTHR10366:SF77 71 334 7.0E-165 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 PANTHER PTHR10366:SF77 2 53 7.0E-165 T 22-04-2016 MED134_RS01365 d48b9f2da462ef5ef51c19f40fe2c3e2 335 Gene3D G3DSA:3.40.50.720 1 214 1.2E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 97 106 2.6E-9 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.6E-9 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 96 2.6E-9 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 134 3.3E-38 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 PANTHER PTHR30266:SF2 1 135 1.5E-33 T 22-04-2016 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 PANTHER PTHR30266 1 135 1.5E-33 T 22-04-2016 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 134 1.1E-33 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS09850 e22df62fadff311b12bd2fe5e1fe9612 135 SUPERFAMILY SSF81330 10 130 5.62E-28 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 Gene3D G3DSA:3.30.750.24 514 595 2.1E-4 T 22-04-2016 IPR002645 STAS domain MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 PANTHER PTHR11814 6 206 1.1E-129 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 PANTHER PTHR11814 267 594 1.1E-129 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 PANTHER PTHR11814:SF76 6 206 1.1E-129 T 22-04-2016 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 PANTHER PTHR11814:SF76 267 594 1.1E-129 T 22-04-2016 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 SUPERFAMILY SSF52091 513 595 8.44E-9 T 22-04-2016 IPR002645 STAS domain MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 Pfam PF00916 Sulfate permease family 14 153 7.7E-26 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MED134_RS14495 add20b99f59088fe4c2209df405530bb 623 Pfam PF00916 Sulfate permease family 250 473 1.6E-28 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 PANTHER PTHR11014 32 442 8.2E-38 T 22-04-2016 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 SUPERFAMILY SSF55031 224 347 1.74E-7 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 Gene3D G3DSA:3.30.70.360 225 346 1.9E-12 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 Gene3D G3DSA:3.40.630.10 350 439 6.1E-41 T 22-04-2016 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 Gene3D G3DSA:3.40.630.10 34 224 6.1E-41 T 22-04-2016 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 Pfam PF07687 Peptidase dimerisation domain 221 339 1.3E-10 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 Pfam PF01546 Peptidase family M20/M25/M40 116 434 1.7E-22 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 SUPERFAMILY SSF53187 36 233 4.72E-45 T 22-04-2016 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 SUPERFAMILY SSF53187 361 439 4.72E-45 T 22-04-2016 MED134_RS10085 2264eedcb9e8e0644a8ceb498dca2d94 442 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 115 124 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 364 1.4E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PANTHER PTHR24423 4 16 1.1E-53 T 22-04-2016 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PANTHER PTHR24423 288 524 1.1E-53 T 22-04-2016 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 524 5.6E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 Gene3D G3DSA:3.30.565.10 353 524 3.1E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 SMART SM00387 412 526 7.3E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 SUPERFAMILY SSF47384 286 367 1.73E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 9.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 523 9.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 479 9.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 504 9.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 SUPERFAMILY SSF55874 356 524 6.37E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 SMART SM00388 298 366 1.3E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS05170 2a133d5b49c15c520309c3e4c1741f13 527 Gene3D G3DSA:1.10.287.130 290 352 4.0E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 SUPERFAMILY SSF47729 1 90 3.68E-25 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 Gene3D G3DSA:4.10.520.10 1 91 2.5E-29 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 8.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 8.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 8.1E-8 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 SMART SM00411 1 90 2.1E-26 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 PANTHER PTHR33175 1 96 2.1E-31 T 22-04-2016 MED134_RS10230 9743a637f661e798eb674755a0be8000 96 Pfam PF00216 Bacterial DNA-binding protein 1 89 2.7E-27 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 PANTHER PTHR11133 1 446 1.3E-131 T 22-04-2016 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 121 2.0E-13 T 22-04-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 SUPERFAMILY SSF55347 127 385 4.38E-53 T 22-04-2016 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 SUPERFAMILY SSF51735 1 179 9.34E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 PANTHER PTHR11133:SF14 1 446 1.3E-131 T 22-04-2016 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 Gene3D G3DSA:3.40.50.720 2 125 2.0E-8 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 Gene3D G3DSA:3.30.360.10 128 252 1.3E-51 T 22-04-2016 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 Gene3D G3DSA:3.30.360.10 350 395 1.3E-51 T 22-04-2016 MED134_RS10180 28046996c5b9df14a6fbf78984c56334 456 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 126 437 2.1E-78 T 22-04-2016 IPR032095 Saccharopine dehydrogenase, C-terminal MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 Gene3D G3DSA:1.10.238.10 37 86 5.7E-8 T 22-04-2016 IPR011992 EF-hand domain pair MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 SUPERFAMILY SSF47473 38 86 1.89E-9 T 22-04-2016 IPR011992 EF-hand domain pair MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 ProSitePatterns PS00018 EF-hand calcium-binding domain. 71 83 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 ProSitePatterns PS00018 EF-hand calcium-binding domain. 47 59 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 Pfam PF13202 EF hand 42 60 0.051 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 MED134_RS10565 46b55a1e84519e6f9be963a03858f642 98 Pfam PF00036 EF hand 63 86 1.9E-7 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 Gene3D G3DSA:3.30.565.10 650 801 1.6E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 SUPERFAMILY SSF116734 394 571 4.74E-10 T 22-04-2016 MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 SUPERFAMILY SSF53335 30 393 1.55E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 Gene3D G3DSA:3.40.50.150 151 345 9.8E-15 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 Pfam PF02384 N-6 DNA Methylase 129 356 2.1E-25 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 Pfam PF01420 Type I restriction modification DNA specificity domain 412 561 1.8E-4 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 Pfam PF14501 GHKL domain 701 797 1.5E-6 T 22-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain MED134_RS00385 470954658f127e2279aa8ff6f93e0ffd 833 SUPERFAMILY SSF55874 695 801 3.19E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06555 1a93b8dda83215bd667157c3cd60828f 275 PIRSF PIRSF000883 13 257 1.5E-32 T 22-04-2016 IPR011152 Phosphoesterase MJ0912 MED134_RS06555 1a93b8dda83215bd667157c3cd60828f 275 Gene3D G3DSA:3.60.21.10 15 254 1.6E-45 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS06555 1a93b8dda83215bd667157c3cd60828f 275 SUPERFAMILY SSF56300 14 78 9.07E-28 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS06555 1a93b8dda83215bd667157c3cd60828f 275 SUPERFAMILY SSF56300 120 237 9.07E-28 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS06555 1a93b8dda83215bd667157c3cd60828f 275 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 24 213 5.1E-12 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type MED134_RS10505 a2f6931e51ab3726e83e8d2e8a22e3c6 765 Pfam PF07940 Heparinase II/III-like protein 408 669 2.0E-33 T 22-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 MED134_RS10505 a2f6931e51ab3726e83e8d2e8a22e3c6 765 Pfam PF05426 Alginate lyase 83 336 6.6E-21 T 22-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 MED134_RS10505 a2f6931e51ab3726e83e8d2e8a22e3c6 765 Gene3D G3DSA:1.50.10.110 40 391 4.9E-74 T 22-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 MED134_RS10505 a2f6931e51ab3726e83e8d2e8a22e3c6 765 SUPERFAMILY SSF48230 271 371 1.65E-52 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase MED134_RS10505 a2f6931e51ab3726e83e8d2e8a22e3c6 765 SUPERFAMILY SSF48230 85 244 1.65E-52 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PIRSF PIRSF000904 2 334 4.3E-123 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 273 285 - T 22-04-2016 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 Gene3D G3DSA:3.30.540.10 6 200 6.3E-75 T 22-04-2016 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 68 94 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 210 237 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 31 58 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 184 207 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 153 176 3.8E-73 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 7 198 3.5E-72 T 22-04-2016 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 SUPERFAMILY SSF56655 3 331 1.83E-111 T 22-04-2016 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 Gene3D G3DSA:3.40.190.80 201 332 9.0E-58 T 22-04-2016 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 6 333 42.207 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PANTHER PTHR11556 7 331 1.1E-178 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 MED134_RS08185 67df095c471bc786001656e6f62cf18a 334 PIRSF PIRSF500210 2 334 2.8E-125 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 MED134_RS06325 5f40bf100dc34ceaeb8b8693de59a5d3 2897 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 2805 2897 1.0E-34 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS06325 5f40bf100dc34ceaeb8b8693de59a5d3 2897 Pfam PF13585 C-terminal domain of CHU protein family 2806 2879 2.5E-10 T 22-04-2016 MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 TIGRFAM TIGR02695 azurin: azurin 49 165 5.5E-32 T 22-04-2016 IPR014068 Azurin, proteobacteria MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 SUPERFAMILY SSF49503 49 168 6.81E-40 T 22-04-2016 IPR008972 Cupredoxin MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 PANTHER PTHR38439 45 168 3.4E-32 T 22-04-2016 MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 49 168 1.3E-19 T 22-04-2016 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 PANTHER PTHR38439:SF2 45 168 3.4E-32 T 22-04-2016 MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 49 165 1.0E-22 T 22-04-2016 MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 145 161 - T 22-04-2016 IPR028871 Blue (type 1) copper protein, binding site MED134_RS09745 ecf9e1c301663245b7f8cf7b734d87ce 168 Gene3D G3DSA:2.60.40.420 48 168 1.1E-42 T 22-04-2016 IPR008972 Cupredoxin MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081:SF1 180 239 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081:SF1 372 644 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081:SF1 80 131 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 697 968 4.1E-68 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 SUPERFAMILY SSF82866 757 786 1.83E-35 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 SUPERFAMILY SSF82866 817 973 1.83E-35 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Pfam PF07549 SecD/SecF GG Motif 701 717 5.9E-5 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 793 965 4.0E-47 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 405 636 2.7E-75 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081 180 239 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081 372 644 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PANTHER PTHR30081 80 131 5.0E-102 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Gene3D G3DSA:1.20.1640.10 451 643 2.6E-32 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Gene3D G3DSA:1.20.1640.10 759 988 6.8E-31 T 22-04-2016 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PRINTS PR01755 Bacterial translocase SecF protein signature 916 931 1.5E-18 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PRINTS PR01755 Bacterial translocase SecF protein signature 696 711 1.5E-18 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 PRINTS PR01755 Bacterial translocase SecF protein signature 883 901 1.5E-18 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 83 643 2.9E-116 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Pfam PF02355 Protein export membrane protein 787 975 5.9E-58 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Pfam PF02355 Protein export membrane protein 474 640 2.3E-26 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 669 979 26.388 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 655 35.348 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MED134_RS12765 e6deaf738a880310956a5635a675fb10 992 SUPERFAMILY SSF82866 453 643 3.01E-45 T 22-04-2016 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 313 6.7E-56 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 Gene3D G3DSA:3.40.50.720 2 161 6.6E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PIRSF PIRSF000149 2 333 1.4E-116 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 5 325 3.5E-118 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 5 153 4.1E-54 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 Gene3D G3DSA:3.30.360.10 162 315 9.3E-63 T 22-04-2016 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PANTHER PTHR10836 4 333 2.6E-162 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PANTHER PTHR10836:SF50 4 333 2.6E-162 T 22-04-2016 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 SMART SM00846 4 153 4.5E-74 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 5.1E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 5.1E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 5.1E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 5.1E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 5.1E-30 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 SUPERFAMILY SSF55347 153 314 4.17E-61 T 22-04-2016 MED134_RS05875 ba29f6db8295a3fa1fa3a58448b8676d 333 SUPERFAMILY SSF51735 5 157 6.17E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 PIRSF PIRSF035805 11 199 2.8E-58 T 22-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 Gene3D G3DSA:3.30.60.20 147 189 2.0E-10 T 22-04-2016 MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 SUPERFAMILY SSF57716 147 192 2.8E-8 T 22-04-2016 MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 PANTHER PTHR11441 11 196 6.3E-82 T 22-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 SUPERFAMILY SSF52540 13 146 1.81E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 Pfam PF00265 Thymidine kinase 14 186 1.1E-49 T 22-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 MED134_RS09840 1f340cf9d179ed9e30fa019243d8fc48 218 Hamap MF_00124 Thymidine kinase [tdk]. 13 189 30.638 T 22-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 MED134_RS09830 da2a4f25a207545750dae5470916eac2 120 Pfam PF13564 DoxX-like family 11 107 2.5E-13 T 22-04-2016 IPR032808 DoxX family MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 SUPERFAMILY SSF51735 5 247 2.18E-90 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PANTHER PTHR24322 11 140 1.1E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PANTHER PTHR24322 156 188 1.1E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PANTHER PTHR24322:SF328 11 140 1.1E-60 T 22-04-2016 MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PANTHER PTHR24322:SF328 156 188 1.1E-60 T 22-04-2016 MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.801159E-49 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 Gene3D G3DSA:3.40.50.720 2 247 2.5E-93 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 246 4.8E-103 T 22-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.69565E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.69565E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 9.69565E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 192 1.3E-5 T 22-04-2016 MED134_RS02480 1ee3d95697f43593cc47e41448b4ad67 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 5.8E-73 T 22-04-2016 MED134_RS11815 fb4872c1ff7506275b82ddac559c258d 286 Pfam PF00892 EamA-like transporter family 148 277 1.5E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS11815 fb4872c1ff7506275b82ddac559c258d 286 Pfam PF00892 EamA-like transporter family 12 136 9.7E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS11815 fb4872c1ff7506275b82ddac559c258d 286 PANTHER PTHR22911 14 286 2.7E-46 T 22-04-2016 MED134_RS11815 fb4872c1ff7506275b82ddac559c258d 286 SUPERFAMILY SSF103481 39 137 2.22E-10 T 22-04-2016 MED134_RS11815 fb4872c1ff7506275b82ddac559c258d 286 SUPERFAMILY SSF103481 185 281 4.45E-11 T 22-04-2016 MED134_RS05585 8277ce2301668fa1d8dcf593fb51fe67 622 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 46 201 2.6E-11 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 MED134_RS05585 8277ce2301668fa1d8dcf593fb51fe67 622 SUPERFAMILY SSF54001 253 378 8.34E-9 T 22-04-2016 MED134_RS05585 8277ce2301668fa1d8dcf593fb51fe67 622 Pfam PF01841 Transglutaminase-like superfamily 263 377 1.4E-5 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 PIRSF PIRSF029883 9 115 1.0E-39 T 22-04-2016 IPR025499 Pectin degradation protein KdgF UniPathway: UPA00545 MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 Pfam PF07883 Cupin domain 41 104 4.0E-15 T 22-04-2016 IPR013096 Cupin 2, conserved barrel MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 SUPERFAMILY SSF51182 17 108 1.78E-24 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 PANTHER PTHR40112 2 115 3.2E-23 T 22-04-2016 MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 Gene3D G3DSA:2.60.120.10 7 114 6.5E-34 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS10500 e0cc29d20c4c48cbc8f8a17ddb139b8d 115 PANTHER PTHR40112:SF1 2 115 3.2E-23 T 22-04-2016 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 Gene3D G3DSA:3.40.50.790 69 159 1.2E-37 T 22-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 40.153 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.2E-93 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 SUPERFAMILY SSF56808 6 225 7.72E-76 T 22-04-2016 IPR023674 Ribosomal protein L1-like MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 PIRSF PIRSF002155 1 227 3.9E-71 T 22-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 PANTHER PTHR23105:SF5 19 229 1.1E-71 T 22-04-2016 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 22-04-2016 IPR023673 Ribosomal protein L1, conserved site MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 Gene3D G3DSA:3.30.190.20 18 68 8.6E-43 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 Gene3D G3DSA:3.30.190.20 161 227 8.6E-43 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 PANTHER PTHR23105 19 229 1.1E-71 T 22-04-2016 MED134_RS04900 24492347e14293494f5cbbcf566922b6 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.1E-49 T 22-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MED134_RS02670 976d1b157cae0d954705721348e543ac 214 Pfam PF13460 NAD(P)H-binding 8 186 1.0E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02670 976d1b157cae0d954705721348e543ac 214 Gene3D G3DSA:3.40.50.720 1 201 1.6E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02670 976d1b157cae0d954705721348e543ac 214 PANTHER PTHR15020 3 209 3.6E-39 T 22-04-2016 MED134_RS02670 976d1b157cae0d954705721348e543ac 214 SUPERFAMILY SSF51735 2 200 1.08E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02670 976d1b157cae0d954705721348e543ac 214 PANTHER PTHR15020:SF11 3 209 3.6E-39 T 22-04-2016 MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 Gene3D G3DSA:2.60.120.560 353 514 9.7E-23 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 42 347 2.6E-99 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 Gene3D G3DSA:2.120.10.10 88 226 8.0E-12 T 22-04-2016 IPR011040 Sialidases MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 SUPERFAMILY SSF49899 380 513 1.06E-19 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 SMART SM00640 42 475 4.8E-138 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 PANTHER PTHR30175:SF0 34 486 4.8E-141 T 22-04-2016 MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 402 475 7.8E-9 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 PANTHER PTHR30175 34 486 4.8E-141 T 22-04-2016 MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 SUPERFAMILY SSF75005 35 347 2.23E-107 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MED134_RS10595 5f3f4765d900d378c616dc908c98e94b 514 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 42 55 - T 22-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 PRINTS PR01270 Histone deacetylase superfamily signature 224 234 1.3E-12 T 22-04-2016 IPR000286 Histone deacetylase superfamily MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 PRINTS PR01270 Histone deacetylase superfamily signature 150 165 1.3E-12 T 22-04-2016 IPR000286 Histone deacetylase superfamily MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 PRINTS PR01270 Histone deacetylase superfamily signature 116 139 1.3E-12 T 22-04-2016 IPR000286 Histone deacetylase superfamily MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 PANTHER PTHR10625 10 290 1.7E-101 T 22-04-2016 IPR000286 Histone deacetylase superfamily MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 Gene3D G3DSA:3.40.800.20 5 281 3.9E-64 T 22-04-2016 IPR023801 Histone deacetylase domain MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 SUPERFAMILY SSF52768 4 281 4.65E-79 T 22-04-2016 MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 Pfam PF00850 Histone deacetylase domain 39 280 2.4E-51 T 22-04-2016 IPR023801 Histone deacetylase domain MED134_RS08475 3804e3de122d7f4a6c3fe81ec02d4183 300 PANTHER PTHR10625:SF131 10 290 1.7E-101 T 22-04-2016 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 2.1E-70 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 SUPERFAMILY SSF50249 65 127 2.4E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Gene3D G3DSA:2.40.50.140 129 186 2.1E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 PIRSF PIRSF005901 1 187 5.8E-62 T 22-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 PANTHER PTHR30053 1 187 1.3E-73 T 22-04-2016 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 SUPERFAMILY SSF50249 130 186 2.57E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 44.234 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 SUPERFAMILY SSF50104 1 63 1.75E-19 T 22-04-2016 IPR008991 Translation protein SH3-like domain MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 SMART SM01185 67 122 2.2E-19 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 114 3.9E-16 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 1.1E-26 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 SMART SM00841 130 185 2.6E-32 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Gene3D G3DSA:2.30.30.30 3 63 7.6E-28 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 22-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Gene3D G3DSA:2.40.50.140 64 128 1.2E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS02500 1558ac1c87d6fc6d310ab80f8bec22bf 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.8E-24 T 22-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Pfam PF13643 Domain of unknown function (DUF4145) 22 111 4.3E-7 T 22-04-2016 IPR025285 Domain of unknown function DUF4145 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Pfam PF00271 Helicase conserved C-terminal domain 642 745 1.1E-9 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Pfam PF08463 EcoEI R protein C-terminal 1023 1159 6.7E-14 T 22-04-2016 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 PANTHER PTHR30195:SF3 72 1135 4.8E-184 T 22-04-2016 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Gene3D G3DSA:3.40.50.300 625 745 1.2E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 SMART SM00487 360 560 4.4E-19 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 PANTHER PTHR30195 72 1135 4.8E-184 T 22-04-2016 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Gene3D G3DSA:3.40.50.300 362 534 1.6E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 SUPERFAMILY SSF52540 319 582 1.33E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 Pfam PF04851 Type III restriction enzyme, res subunit 364 529 1.2E-32 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 SUPERFAMILY SSF52540 493 526 2.02E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 SUPERFAMILY SSF52540 580 604 2.02E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00335 826ab8f9f126ad8cacd2943f60677d5d 1168 SUPERFAMILY SSF52540 644 767 2.02E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 PANTHER PTHR12110 31 338 2.4E-27 T 22-04-2016 MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 Pfam PF01261 Xylose isomerase-like TIM barrel 29 279 2.0E-37 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 Pfam PF07582 AP endonuclease family 2 C terminus 280 334 2.5E-20 T 22-04-2016 IPR011418 AP endonuclease, family 2, C-terminal MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 SUPERFAMILY SSF51658 9 323 2.07E-58 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 Gene3D G3DSA:3.20.20.150 8 324 1.2E-68 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09550 af3ee4316ae7487ff533de89ab73813e 350 PANTHER PTHR12110:SF17 31 338 2.4E-27 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 SUPERFAMILY SSF51905 1 201 2.07E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 SUPERFAMILY SSF51905 352 410 2.07E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 Pfam PF03486 HI0933-like protein 5 407 1.8E-110 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 SUPERFAMILY SSF160996 194 355 4.45E-39 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PANTHER PTHR10617 1 304 6.4E-126 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PANTHER PTHR10617 345 409 6.4E-126 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 407 4.7E-122 T 22-04-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.0E-7 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 178 2.0E-7 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 2.0E-7 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PANTHER PTHR10617:SF103 1 304 6.4E-126 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PANTHER PTHR10617:SF103 345 409 6.4E-126 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 Gene3D G3DSA:3.50.50.60 1 196 9.6E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 Gene3D G3DSA:3.50.50.60 354 410 9.6E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 Gene3D G3DSA:2.40.30.10 197 283 8.4E-22 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 8.8E-7 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 8.8E-7 T 22-04-2016 MED134_RS10660 b963a3c8355c727f72164ed67c10cee5 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.8E-7 T 22-04-2016 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 150 160 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 102 118 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 Gene3D G3DSA:3.30.1130.10 97 222 6.9E-50 T 22-04-2016 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 Gene3D G3DSA:1.10.286.10 10 90 4.2E-28 T 22-04-2016 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 40 222 32.459 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 Pfam PF01227 GTP cyclohydrolase I 44 221 2.7E-65 T 22-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 PANTHER PTHR11109 28 224 8.7E-75 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 SUPERFAMILY SSF55620 16 222 5.56E-71 T 22-04-2016 MED134_RS05045 347dd1981a9a7441e3a48e502718875f 227 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 44 222 8.1E-68 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 PANTHER PTHR13710 1 340 9.5E-168 T 22-04-2016 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Pfam PF00271 Helicase conserved C-terminal domain 222 321 4.2E-17 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Gene3D G3DSA:1.10.10.10 519 575 3.7E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 PANTHER PTHR13710 516 610 9.5E-168 T 22-04-2016 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Gene3D G3DSA:3.40.50.300 5 195 4.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 SMART SM00487 13 209 2.1E-34 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 PANTHER PTHR13710:SF81 1 340 9.5E-168 T 22-04-2016 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 SMART SM00490 240 321 3.3E-25 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Gene3D G3DSA:3.40.50.300 198 334 6.3E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Pfam PF16124 RecQ zinc-binding 519 565 8.3E-11 T 22-04-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 SUPERFAMILY SSF52540 57 337 3.67E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 361 3.4E-117 T 22-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 PANTHER PTHR13710:SF81 516 610 9.5E-168 T 22-04-2016 MED134_RS13990 d02a8d6c95dbbb08a6f2468ebecac75c 628 Pfam PF00270 DEAD/DEAH box helicase 19 180 4.6E-20 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Pfam PF07687 Peptidase dimerisation domain 210 308 1.5E-9 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Gene3D G3DSA:3.40.630.10 326 411 2.5E-124 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Gene3D G3DSA:3.40.630.10 1 213 2.5E-124 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 142 181 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Pfam PF01546 Peptidase family M20/M25/M40 143 405 3.4E-14 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 SUPERFAMILY SSF55031 213 323 4.76E-37 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 TIGRFAM TIGR01882 peptidase-T: peptidase T 5 410 3.7E-183 T 22-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Gene3D G3DSA:3.30.70.360 214 323 1.1E-43 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 PANTHER PTHR11014 135 413 6.9E-190 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 PANTHER PTHR11014 1 94 6.9E-190 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 PANTHER PTHR11014:SF3 135 413 6.9E-190 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 PANTHER PTHR11014:SF3 1 94 6.9E-190 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 Hamap MF_00550 Peptidase T [pepT]. 4 408 57.218 T 22-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 PIRSF PIRSF037215 2 412 3.1E-192 T 22-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 SUPERFAMILY SSF53187 326 410 1.1E-81 T 22-04-2016 MED134_RS00945 828f0b1d224abe584637fea0970fcb4d 413 SUPERFAMILY SSF53187 5 214 1.1E-81 T 22-04-2016 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Gene3D G3DSA:3.40.50.300 209 242 5.4E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Gene3D G3DSA:3.40.50.300 3 144 9.3E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Gene3D G3DSA:1.10.3710.10 333 422 1.9E-30 T 22-04-2016 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 417 9.5E-72 T 22-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Gene3D G3DSA:1.20.272.10 243 332 8.1E-47 T 22-04-2016 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 153 1.8E-16 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 SUPERFAMILY SSF52540 3 211 1.01E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Pfam PF16193 AAA C-terminal domain 185 252 2.4E-22 T 22-04-2016 IPR032423 AAA ATPase, C-terminal domain MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 Gene3D G3DSA:1.10.8.60 145 208 1.9E-7 T 22-04-2016 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 SUPERFAMILY SSF48019 238 421 1.76E-77 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 SMART SM00382 38 156 2.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 PANTHER PTHR13779:SF7 2 419 5.2E-193 T 22-04-2016 MED134_RS12175 778b763f56485d2c6bcb673fe1c3b3a6 425 PANTHER PTHR13779 2 419 5.2E-193 T 22-04-2016 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 Pfam PF00501 AMP-binding enzyme 51 208 8.9E-16 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 SUPERFAMILY SSF56801 60 362 1.1E-38 T 22-04-2016 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 Gene3D G3DSA:3.30.300.30 265 355 3.5E-10 T 22-04-2016 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 PANTHER PTHR24095:SF17 56 364 9.5E-20 T 22-04-2016 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 Gene3D G3DSA:3.40.50.980 60 207 5.6E-15 T 22-04-2016 MED134_RS04525 bd7f59146df8ad3c0cbdd1fbe2704d07 364 PANTHER PTHR24095 56 364 9.5E-20 T 22-04-2016 MED134_RS05810 3f49ecc0dc0943387112d3b210da2016 170 SMART SM00554 58 169 2.2E-22 T 22-04-2016 IPR000782 FAS1 domain MED134_RS05810 3f49ecc0dc0943387112d3b210da2016 170 Gene3D G3DSA:2.30.180.10 23 168 1.6E-35 T 22-04-2016 IPR000782 FAS1 domain MED134_RS05810 3f49ecc0dc0943387112d3b210da2016 170 PANTHER PTHR10900 21 170 7.8E-37 T 22-04-2016 MED134_RS05810 3f49ecc0dc0943387112d3b210da2016 170 Pfam PF02469 Fasciclin domain 34 168 5.2E-30 T 22-04-2016 IPR000782 FAS1 domain MED134_RS05810 3f49ecc0dc0943387112d3b210da2016 170 SUPERFAMILY SSF82153 24 168 3.79E-37 T 22-04-2016 IPR000782 FAS1 domain MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.3E-36 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 PANTHER PTHR21349 1 123 3.5E-41 T 22-04-2016 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 Pfam PF14520 Helix-hairpin-helix domain 146 187 9.6E-9 T 22-04-2016 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 Gene3D G3DSA:1.10.150.20 144 187 1.6E-8 T 22-04-2016 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.4E-30 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 SUPERFAMILY SSF141091 1 101 8.37E-35 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 Gene3D G3DSA:2.40.50.140 68 130 2.8E-4 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 22-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06005 1c9734d1c6bda20ba0aae1aaf5758be6 224 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 24.944 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 PANTHER PTHR10513 1 196 1.5E-80 T 22-04-2016 MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 PIRSF PIRSF000705 1 203 3.3E-63 T 22-04-2016 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 Pfam PF01712 Deoxynucleoside kinase 3 198 9.1E-59 T 22-04-2016 IPR031314 Deoxynucleoside kinase domain MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 SUPERFAMILY SSF52540 1 198 2.12E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 Gene3D G3DSA:3.40.50.300 1 198 1.3E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07165 c09d450cac1d7135b4b5cb33e1e7fd37 204 PANTHER PTHR10513:SF17 1 196 1.5E-80 T 22-04-2016 MED134_RS14235 76fe9438152460fe5fe30913a63f6e0d 173 Pfam PF14060 Domain of unknown function (DUF4252) 2 153 6.4E-39 T 22-04-2016 IPR025348 Protein of unknown function DUF4252 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 SMART SM00344 10 117 2.3E-38 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 Gene3D G3DSA:3.30.70.920 63 144 1.9E-23 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 1.2E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 1.2E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 1.2E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 SUPERFAMILY SSF54909 73 152 1.88E-19 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 PANTHER PTHR30154:SF2 1 156 2.7E-50 T 22-04-2016 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 28 54 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 56 5.6E-13 T 22-04-2016 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 Pfam PF01037 Lrp/AsnC ligand binding domain 76 147 1.1E-18 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 Gene3D G3DSA:1.10.10.10 10 59 1.6E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 PANTHER PTHR30154 1 156 2.7E-50 T 22-04-2016 MED134_RS10175 dc02ad1685604c2c2bb293ecb29df156 156 SUPERFAMILY SSF46785 9 70 6.52E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Gene3D G3DSA:3.40.50.2300 383 514 1.5E-34 T 22-04-2016 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Pfam PF00072 Response regulator receiver domain 388 502 4.4E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 247 357 9.0E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PANTHER PTHR24423 1 8 8.0E-117 T 22-04-2016 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PANTHER PTHR24423 133 513 8.0E-117 T 22-04-2016 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SUPERFAMILY SSF47384 123 201 7.26E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SMART SM00448 386 502 2.5E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SMART SM00387 247 361 8.2E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SUPERFAMILY SSF52172 384 515 1.11E-32 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Gene3D G3DSA:1.10.287.130 129 196 6.5E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SMART SM00388 135 200 1.1E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Pfam PF00512 His Kinase A (phospho-acceptor) domain 136 200 9.6E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 316 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 302 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 SUPERFAMILY SSF55874 189 357 1.27E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08165 f485d67967e63df54967451ebb25b3ee 523 Gene3D G3DSA:3.30.565.10 207 357 5.2E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02690 88ba4c169164e0903cb7bd8f28557fb9 291 Pfam PF01048 Phosphorylase superfamily 29 277 6.4E-33 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS02690 88ba4c169164e0903cb7bd8f28557fb9 291 Gene3D G3DSA:3.40.50.1580 22 289 7.6E-76 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS02690 88ba4c169164e0903cb7bd8f28557fb9 291 PANTHER PTHR21234:SF8 10 290 4.2E-53 T 22-04-2016 MED134_RS02690 88ba4c169164e0903cb7bd8f28557fb9 291 PANTHER PTHR21234 10 290 4.2E-53 T 22-04-2016 IPR018017 Nucleoside phosphorylase MED134_RS02690 88ba4c169164e0903cb7bd8f28557fb9 291 SUPERFAMILY SSF53167 15 290 2.86E-48 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 Gene3D G3DSA:3.40.50.280 547 705 1.4E-70 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 Pfam PF02310 B12 binding domain 582 698 1.8E-15 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 579 703 3.6E-61 T 22-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 PANTHER PTHR23408 18 686 0.0 T 22-04-2016 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 SUPERFAMILY SSF52242 546 705 3.14E-57 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 Gene3D G3DSA:3.20.20.240 27 492 1.9E-206 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 SUPERFAMILY SSF51703 18 542 5.1E-217 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 PANTHER PTHR23408:SF1 18 686 0.0 T 22-04-2016 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 547 5.7E-269 T 22-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 369 394 - T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 MED134_RS07650 0b404feb93b96b5984161150a5528af2 707 Pfam PF01642 Methylmalonyl-CoA mutase 27 540 6.4E-238 T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 MED134_RS13615 4c75d6fa7160089e2a5813a7411b4a64 426 Pfam PF01943 Polysaccharide biosynthesis protein 18 245 3.0E-8 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MED134_RS13615 4c75d6fa7160089e2a5813a7411b4a64 426 PANTHER PTHR30250 4 418 5.2E-39 T 22-04-2016 MED134_RS13615 4c75d6fa7160089e2a5813a7411b4a64 426 PANTHER PTHR30250:SF9 4 418 5.2E-39 T 22-04-2016 MED134_RS13085 9427f4ea360b170e37d72d2016b72a60 110 SMART SM00450 11 108 9.0E-25 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13085 9427f4ea360b170e37d72d2016b72a60 110 Gene3D G3DSA:3.40.250.10 4 110 2.5E-32 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13085 9427f4ea360b170e37d72d2016b72a60 110 Pfam PF00581 Rhodanese-like domain 12 104 1.7E-22 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13085 9427f4ea360b170e37d72d2016b72a60 110 SUPERFAMILY SSF52821 5 109 4.32E-30 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS01710 ed1cfde8bfe06f731279b3e8405503cf 136 SUPERFAMILY SSF46785 5 133 6.82E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01710 ed1cfde8bfe06f731279b3e8405503cf 136 Pfam PF01475 Ferric uptake regulator family 12 123 1.5E-9 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MED134_RS01710 ed1cfde8bfe06f731279b3e8405503cf 136 Gene3D G3DSA:1.10.10.10 2 77 3.7E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 Gene3D G3DSA:3.40.50.450 2 212 2.5E-72 T 22-04-2016 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 ProSitePatterns PS00433 Phosphofructokinase signature. 252 270 - T 22-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 248 270 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 125 142 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 97 113 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 35 48 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 10 29 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 217 229 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 143 161 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 163 179 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 181 198 4.0E-81 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PIRSF PIRSF000532 4 328 5.8E-115 T 22-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 7 309 2.3E-122 T 22-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 SUPERFAMILY SSF53784 3 322 5.76E-115 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PANTHER PTHR13697 3 319 2.9E-131 T 22-04-2016 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 PANTHER PTHR13697:SF4 3 319 2.9E-131 T 22-04-2016 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 Pfam PF00365 Phosphofructokinase 7 283 1.0E-106 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01050 0e60734bbcf5e59c458e68485268eecd 328 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 5 327 43.288 T 22-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS11135 f076bf297847fa26ee9ae35b1284b0aa 408 Pfam PF00149 Calcineurin-like phosphoesterase 161 340 2.4E-12 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS11135 f076bf297847fa26ee9ae35b1284b0aa 408 Gene3D G3DSA:3.60.21.10 160 347 8.2E-26 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS11135 f076bf297847fa26ee9ae35b1284b0aa 408 PANTHER PTHR31302 5 406 1.5E-63 T 22-04-2016 MED134_RS11135 f076bf297847fa26ee9ae35b1284b0aa 408 SUPERFAMILY SSF56300 157 404 3.01E-33 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS11135 f076bf297847fa26ee9ae35b1284b0aa 408 PANTHER PTHR31302:SF6 5 406 1.5E-63 T 22-04-2016 MED134_RS03870 477f16c321bd189c5359be707fd713b7 319 PANTHER PTHR21666 63 310 4.7E-61 T 22-04-2016 MED134_RS03870 477f16c321bd189c5359be707fd713b7 319 Gene3D G3DSA:1.10.530.10 99 251 1.1E-38 T 22-04-2016 MED134_RS03870 477f16c321bd189c5359be707fd713b7 319 SUPERFAMILY SSF53955 68 242 1.83E-30 T 22-04-2016 IPR023346 Lysozyme-like domain MED134_RS03870 477f16c321bd189c5359be707fd713b7 319 Pfam PF01464 Transglycosylase SLT domain 113 211 3.9E-19 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 MED134_RS03870 477f16c321bd189c5359be707fd713b7 319 PANTHER PTHR21666:SF182 63 310 4.7E-61 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 PANTHER PTHR30307:SF0 2 349 7.2E-151 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 Pfam PF02547 Queuosine biosynthesis protein 3 348 5.0E-138 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 Gene3D G3DSA:3.40.1780.10 1 62 3.9E-98 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 Gene3D G3DSA:3.40.1780.10 186 349 3.9E-98 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 PANTHER PTHR30307 2 349 7.2E-151 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 349 4.2E-122 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 SUPERFAMILY SSF111337 1 349 1.16E-128 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 Gene3D G3DSA:2.40.10.240 64 144 1.4E-21 T 22-04-2016 MED134_RS05555 3d0b9a2c7900c796c99299d9b2a05a60 349 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 349 43.702 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 150 21.515 T 22-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 Gene3D G3DSA:3.100.10.10 33 150 4.7E-38 T 22-04-2016 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 PANTHER PTHR12934 1 150 1.4E-68 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 SUPERFAMILY SSF52080 4 149 3.27E-44 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 146 1.6E-46 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 22-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12330 1cc1eeff0361cd0a8be4ee5839a5a8a1 150 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 148 1.3E-40 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 SUPERFAMILY SSF52467 2 223 1.64E-63 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Pfam PF02146 Sir2 family 9 176 7.5E-44 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Gene3D G3DSA:3.30.1600.10 19 57 3.3E-21 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Gene3D G3DSA:3.30.1600.10 106 148 3.3E-21 T 22-04-2016 IPR026591 Sirtuin family, catalytic core small domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 PANTHER PTHR11085:SF17 2 223 2.3E-56 T 22-04-2016 MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 PANTHER PTHR11085 2 223 2.3E-56 T 22-04-2016 IPR003000 Sirtuin family GO:0070403 MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Gene3D G3DSA:3.40.50.1220 65 105 1.5E-33 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Gene3D G3DSA:3.40.50.1220 155 219 1.5E-33 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Gene3D G3DSA:3.40.50.1220 2 17 1.5E-33 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS02285 935caf1d3fb5b3ba2400ec51a6bc7ed6 226 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 2 225 49.992 T 22-04-2016 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 Gene3D G3DSA:1.10.150.240 19 87 1.1E-31 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 62 183 2.4E-12 T 22-04-2016 IPR023214 HAD-like domain MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 Gene3D G3DSA:3.40.50.1000 88 228 3.1E-41 T 22-04-2016 IPR023214 HAD-like domain MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 PANTHER PTHR12725:SF59 4 228 4.8E-83 T 22-04-2016 MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 PANTHER PTHR12725 4 228 4.8E-83 T 22-04-2016 MED134_RS03540 7591e17b9c9172bd455b4999e05ce63a 229 SUPERFAMILY SSF56784 1 221 2.34E-31 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Gene3D G3DSA:1.25.40.10 164 236 8.8E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Gene3D G3DSA:1.25.40.10 273 371 1.2E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Pfam PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) 532 652 1.1E-5 T 22-04-2016 IPR008410 Cellulose synthase operon C, C-terminal GO:0019867|GO:0030244 UniPathway: UPA00694 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SUPERFAMILY SSF48452 23 220 5.22E-25 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Pfam PF14559 Tetratricopeptide repeat 175 234 3.6E-8 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SUPERFAMILY SSF56935 335 360 1.1E-5 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SUPERFAMILY SSF56935 389 654 1.1E-5 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SUPERFAMILY SSF48452 166 217 1.49E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Pfam PF13432 Tetratricopeptide repeat 101 153 1.8E-4 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 PANTHER PTHR23083 21 227 2.2E-29 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 PANTHER PTHR23083 262 366 2.2E-29 T 22-04-2016 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Gene3D G3DSA:1.25.40.10 23 151 3.4E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 Pfam PF13174 Tetratricopeptide repeat 23 50 0.018 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SMART SM00028 330 363 1.8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SMART SM00028 119 152 0.038 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS00640 2b45d5234bb57b8eb74e26d7da6ba85f 673 SUPERFAMILY SSF48452 276 352 1.49E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05725 75e66d27fc382d7de5666e7313d307bd 185 SUPERFAMILY SSF69118 1 180 3.68E-51 T 22-04-2016 IPR029032 AhpD-like MED134_RS05725 75e66d27fc382d7de5666e7313d307bd 185 PANTHER PTHR35446 1 182 3.7E-58 T 22-04-2016 MED134_RS05725 75e66d27fc382d7de5666e7313d307bd 185 Gene3D G3DSA:1.20.1290.10 1 88 4.6E-26 T 22-04-2016 IPR029032 AhpD-like MED134_RS05725 75e66d27fc382d7de5666e7313d307bd 185 Gene3D G3DSA:1.20.1290.10 138 179 4.6E-26 T 22-04-2016 IPR029032 AhpD-like MED134_RS05725 75e66d27fc382d7de5666e7313d307bd 185 PANTHER PTHR35446:SF1 1 182 3.7E-58 T 22-04-2016 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 SUPERFAMILY SSF52440 1 105 1.17E-28 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 PANTHER PTHR10520 1 420 2.2E-206 T 22-04-2016 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Gene3D G3DSA:3.30.1490.20 124 193 4.6E-24 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 SUPERFAMILY SSF51246 331 421 3.85E-27 T 22-04-2016 IPR011054 Rudiment single hybrid motif MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 420 2.0E-27 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Gene3D G3DSA:3.30.470.20 194 329 3.1E-53 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 104 1.2E-28 T 22-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 SMART SM01209 105 298 5.1E-112 T 22-04-2016 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 421 3.5E-138 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 SUPERFAMILY SSF56059 106 318 1.73E-54 T 22-04-2016 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Gene3D G3DSA:3.40.50.20 2 97 1.8E-29 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 422 36.339 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 105 298 4.1E-67 T 22-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 SMART SM01210 332 422 4.4E-42 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09315 4c03df1ec8e1d0cdf34fa4de068b01a8 422 Gene3D G3DSA:3.90.600.10 333 420 3.7E-30 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 583 594 2.6E-21 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 491 503 2.6E-21 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 512 528 2.6E-21 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 473 485 2.6E-21 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 Pfam PF05649 Peptidase family M13 48 428 3.0E-88 T 22-04-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 Gene3D G3DSA:3.40.390.10 316 431 7.1E-102 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 Gene3D G3DSA:3.40.390.10 472 686 7.1E-102 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 Pfam PF01431 Peptidase family M13 481 683 7.5E-70 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PANTHER PTHR11733 33 686 8.1E-174 T 22-04-2016 IPR000718 Peptidase M13 GO:0004222|GO:0006508 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 SUPERFAMILY SSF55486 36 686 9.03E-191 T 22-04-2016 MED134_RS09715 8d151f187e61f8b65a8d90cbb8818c85 686 PANTHER PTHR11733:SF65 33 686 8.1E-174 T 22-04-2016 MED134_RS08790 c4f28a9e929e63257d96fcd94ddff505 438 PANTHER PTHR21600:SF3 50 313 1.4E-52 T 22-04-2016 MED134_RS08790 c4f28a9e929e63257d96fcd94ddff505 438 Pfam PF04468 PSP1 C-terminal conserved region 116 200 3.6E-24 T 22-04-2016 IPR007557 PSP1, C-terminal MED134_RS08790 c4f28a9e929e63257d96fcd94ddff505 438 PANTHER PTHR21600 50 313 1.4E-52 T 22-04-2016 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 Gene3D G3DSA:3.40.50.10490 159 248 2.2E-61 T 22-04-2016 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 Gene3D G3DSA:3.40.50.10490 24 100 2.2E-61 T 22-04-2016 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 Pfam PF00318 Ribosomal protein S2 10 225 3.3E-90 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 5 225 7.2E-93 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PANTHER PTHR12534 1 246 9.5E-101 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 159 176 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 7 25 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 176 187 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 38 47 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 88 105 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 PRINTS PR00395 Ribosomal protein S2 signature 197 211 5.9E-36 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 7 18 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 3 233 38.781 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 SUPERFAMILY SSF52313 7 229 7.59E-86 T 22-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain MED134_RS06805 489737d82dc8b4a905f903cb93c30fd6 266 Gene3D G3DSA:1.10.287.610 101 152 2.4E-22 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 SUPERFAMILY SSF52540 75 288 8.13E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 Gene3D G3DSA:3.30.230.10 285 456 2.3E-33 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 Gene3D G3DSA:3.40.50.300 66 277 4.0E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PANTHER PTHR32472:SF10 1 426 2.5E-185 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 SMART SM00382 93 244 5.8E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 353 454 2.0E-8 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 Pfam PF13481 AAA domain 70 222 1.6E-14 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 SUPERFAMILY SSF54211 303 456 3.6E-34 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 SUPERFAMILY SSF54211 255 269 3.6E-34 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 213 241 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 10 34 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 124 141 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 85 113 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 322 345 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 248 274 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PRINTS PR01874 DNA repair protein radA signature 174 198 2.7E-86 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 PANTHER PTHR32472 1 426 2.5E-185 T 22-04-2016 MED134_RS08015 0f88265d9862ac349138d1fc99aca41d 456 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 451 1.9E-178 T 22-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:1.10.150.20 196 255 1.9E-26 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Pfam PF00476 DNA polymerase family A 572 946 9.4E-155 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SMART SM00475 10 271 1.1E-105 T 22-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SUPERFAMILY SSF88723 10 159 4.91E-48 T 22-04-2016 IPR029060 PIN domain-like MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PANTHER PTHR10133:SF27 5 291 0.0 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PANTHER PTHR10133:SF27 342 948 0.0 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:3.30.420.10 356 561 1.6E-68 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Pfam PF01612 3'-5' exonuclease 358 538 9.2E-38 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SUPERFAMILY SSF56672 543 949 1.11E-151 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 12 177 1.2E-47 T 22-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 ProSitePatterns PS00447 DNA polymerase family A signature. 775 794 - T 22-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:3.30.70.370 840 949 3.5E-64 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:3.30.70.370 683 732 3.5E-64 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:1.20.1060.10 563 682 1.1E-36 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SMART SM00474 357 538 2.0E-39 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 812 823 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 751 764 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 675 697 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 866 882 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 775 800 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 698 713 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 896 909 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 721 744 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 845 2.4E-73 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:1.10.150.20 733 839 3.1E-33 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 183 275 7.9E-29 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PANTHER PTHR10133 5 291 0.0 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 PANTHER PTHR10133 342 948 0.0 T 22-04-2016 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 Gene3D G3DSA:3.40.50.1010 11 195 1.5E-62 T 22-04-2016 IPR029060 PIN domain-like MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SUPERFAMILY SSF53098 369 539 9.19E-47 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SMART SM00279 183 218 4.3E-14 T 22-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SMART SM00482 706 913 2.3E-114 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 TIGRFAM TIGR00593 pola: DNA polymerase I 12 949 2.9E-298 T 22-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06780 2defce9e650c82cf80c70dc08445da97 949 SUPERFAMILY SSF47807 183 293 4.78E-31 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MED134_RS02520 046fd818d92d703ac5192250d659dc98 407 SMART SM00471 52 177 5.4E-8 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS02520 046fd818d92d703ac5192250d659dc98 407 SUPERFAMILY SSF109604 4 404 7.27E-103 T 22-04-2016 MED134_RS02520 046fd818d92d703ac5192250d659dc98 407 Gene3D G3DSA:1.10.3210.10 4 246 1.7E-75 T 22-04-2016 IPR006674 HD domain MED134_RS02520 046fd818d92d703ac5192250d659dc98 407 Pfam PF01966 HD domain 63 132 3.2E-7 T 22-04-2016 IPR006674 HD domain MED134_RS02520 046fd818d92d703ac5192250d659dc98 407 PANTHER PTHR11373 8 315 3.9E-71 T 22-04-2016 MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 PANTHER PTHR38471 6 78 6.5E-14 T 22-04-2016 MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 SUPERFAMILY SSF158446 7 77 1.83E-21 T 22-04-2016 MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 Gene3D G3DSA:1.20.1440.60 6 77 6.2E-19 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 PANTHER PTHR38471:SF2 6 78 6.5E-14 T 22-04-2016 MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 Pfam PF05635 23S rRNA-intervening sequence protein 10 78 9.5E-21 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein MED134_RS10275 8ab296beaeeb656ff31b707a1cbe3c29 85 TIGRFAM TIGR02436 TIGR02436: four helix bundle protein 14 77 2.8E-18 T 22-04-2016 IPR012657 23S rRNA-intervening sequence protein MED134_RS05865 8e825c1f910467154a90a1ba332a7f7b 243 PANTHER PTHR12835 8 242 1.2E-43 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 MED134_RS05865 8e825c1f910467154a90a1ba332a7f7b 243 Pfam PF03099 Biotin/lipoate A/B protein ligase family 9 133 3.6E-14 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MED134_RS05865 8e825c1f910467154a90a1ba332a7f7b 243 SUPERFAMILY SSF55681 3 192 1.56E-43 T 22-04-2016 MED134_RS05865 8e825c1f910467154a90a1ba332a7f7b 243 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 229 4.6E-49 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 MED134_RS05865 8e825c1f910467154a90a1ba332a7f7b 243 Gene3D G3DSA:3.30.930.10 2 191 4.1E-49 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Pfam PF17191 RecG wedge domain 9 167 3.7E-18 T 22-04-2016 IPR033454 RecG, wedge domain MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 19 52 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 625 691 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 300 601 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 250 283 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 103 146 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031 176 196 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 663 4.3E-217 T 22-04-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 SUPERFAMILY SSF50249 6 168 1.49E-38 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 SMART SM00487 266 456 6.4E-36 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 SUPERFAMILY SSF52540 192 451 1.05E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Pfam PF00271 Helicase conserved C-terminal domain 476 587 1.0E-17 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 SUPERFAMILY SSF52540 389 599 1.78E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 19 52 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 625 691 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 300 601 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 250 283 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 103 146 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 PANTHER PTHR24031:SF249 176 196 5.6E-120 T 22-04-2016 MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Gene3D G3DSA:3.40.50.300 261 451 2.5E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Gene3D G3DSA:2.40.50.140 48 142 1.3E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Gene3D G3DSA:3.40.50.300 452 636 5.4E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 SMART SM00490 506 588 1.8E-20 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS03065 a62027929740853c7f61b2bf2e1a0def 700 Pfam PF00270 DEAD/DEAH box helicase 274 432 1.1E-18 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 455 3.6E-71 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain MED134_RS13730 5ce0df94251624312e69c5db77933397 541 Gene3D G3DSA:3.90.76.10 45 195 3.0E-43 T 22-04-2016 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 Gene3D G3DSA:3.40.190.10 196 317 3.9E-25 T 22-04-2016 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 PANTHER PTHR30290 1 536 7.3E-96 T 22-04-2016 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 PIRSF PIRSF002741 5 538 5.9E-91 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 Gene3D G3DSA:3.10.105.10 318 509 3.4E-41 T 22-04-2016 MED134_RS13730 5ce0df94251624312e69c5db77933397 541 SUPERFAMILY SSF53850 36 537 8.69E-110 T 22-04-2016 MED134_RS10855 ef6f69fb71985740c55bb79bd5c1d774 182 SUPERFAMILY SSF55729 8 160 2.92E-27 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS10855 ef6f69fb71985740c55bb79bd5c1d774 182 Gene3D G3DSA:3.40.630.30 8 178 2.9E-25 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS10855 ef6f69fb71985740c55bb79bd5c1d774 182 PANTHER PTHR23091 5 155 4.4E-15 T 22-04-2016 MED134_RS10855 ef6f69fb71985740c55bb79bd5c1d774 182 Pfam PF13673 Acetyltransferase (GNAT) domain 47 154 6.8E-11 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS12835 37d8612f3cf55c27d4bc9abd307ab355 531 PIRSF PIRSF012535 8 531 2.5E-82 T 22-04-2016 IPR011199 Bacillithiol biosynthesis BshC MED134_RS12835 37d8612f3cf55c27d4bc9abd307ab355 531 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 4 531 25.279 T 22-04-2016 IPR011199 Bacillithiol biosynthesis BshC MED134_RS12835 37d8612f3cf55c27d4bc9abd307ab355 531 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 13 528 1.4E-138 T 22-04-2016 IPR011199 Bacillithiol biosynthesis BshC MED134_RS12835 37d8612f3cf55c27d4bc9abd307ab355 531 Pfam PF10079 Uncharacterized protein conserved in bacteria (DUF2317) 1 528 1.6E-197 T 22-04-2016 IPR011199 Bacillithiol biosynthesis BshC MED134_RS12835 37d8612f3cf55c27d4bc9abd307ab355 531 PANTHER PTHR41301 74 531 9.5E-50 T 22-04-2016 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 1 308 33.872 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Pfam PF16745 RsgA N-terminal domain 2 56 2.6E-16 T 22-04-2016 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 SUPERFAMILY SSF50249 1 70 7.43E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 43 301 7.7E-67 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Gene3D G3DSA:2.40.50.140 1 68 1.1E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 PANTHER PTHR32120:SF2 1 301 1.2E-109 T 22-04-2016 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Gene3D G3DSA:1.10.40.50 245 303 2.6E-23 T 22-04-2016 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 SUPERFAMILY SSF52540 82 307 1.61E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Pfam PF03193 Protein of unknown function, DUF258 66 243 2.9E-50 T 22-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 PANTHER PTHR32120 1 301 1.2E-109 T 22-04-2016 MED134_RS05595 2d48fe434a4e1b46bd44d9d2405ab85b 317 Gene3D G3DSA:3.40.50.300 80 242 5.7E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 Pfam PF08282 haloacid dehalogenase-like hydrolase 301 370 7.5E-7 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 Gene3D G3DSA:3.40.50.1000 222 384 8.4E-35 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 Pfam PF02348 Cytidylyltransferase 5 144 1.4E-13 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 PANTHER PTHR21485:SF3 1 387 1.3E-94 T 22-04-2016 MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 SUPERFAMILY SSF56784 230 385 2.71E-34 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 PANTHER PTHR21485 1 387 1.3E-94 T 22-04-2016 MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 Gene3D G3DSA:3.90.550.10 1 221 1.9E-50 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 SUPERFAMILY SSF53448 1 221 9.19E-41 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13420 2f5a12f9792afa6def99e10b90431cf1 387 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 234 384 3.0E-40 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 Pfam PF04542 Sigma-70 region 2 21 86 2.4E-11 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 Gene3D G3DSA:1.10.1740.10 3 108 5.9E-25 T 22-04-2016 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 Gene3D G3DSA:1.10.10.10 113 170 1.7E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 SUPERFAMILY SSF88946 2 107 4.71E-22 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 Pfam PF08281 Sigma-70, region 4 114 164 2.3E-14 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 PANTHER PTHR30173:SF21 1 170 3.5E-44 T 22-04-2016 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 SUPERFAMILY SSF88659 113 170 1.72E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 PANTHER PTHR30173 1 170 3.5E-44 T 22-04-2016 MED134_RS12120 80bf5b8241ec33c1c779a02b22332320 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 169 1.5E-23 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 Gene3D G3DSA:3.40.640.10 496 736 1.0E-40 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 Gene3D G3DSA:3.40.640.10 84 301 6.1E-8 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 9 940 0.0 T 22-04-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 PANTHER PTHR11773:SF1 2 948 0.0 T 22-04-2016 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 946 23.242 T 22-04-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 Pfam PF02347 Glycine cleavage system P-protein 453 727 6.9E-12 T 22-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 Pfam PF02347 Glycine cleavage system P-protein 9 435 2.1E-172 T 22-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 PANTHER PTHR11773 2 948 0.0 T 22-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 MED134_RS11965 217dbb39730140118fa9efe49678c205 949 SUPERFAMILY SSF53383 8 438 9.7E-98 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS11965 217dbb39730140118fa9efe49678c205 949 SUPERFAMILY SSF53383 919 941 2.74E-96 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS11965 217dbb39730140118fa9efe49678c205 949 SUPERFAMILY SSF53383 472 879 2.74E-96 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 TIGRFAM TIGR01499 folC: bifunctional protein FolC 30 404 2.7E-102 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 PIRSF PIRSF001563 3 405 2.0E-106 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 Pfam PF08245 Mur ligase middle domain 51 211 4.3E-11 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 141 156 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 Gene3D G3DSA:3.40.1190.10 1 272 1.6E-82 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 PANTHER PTHR11136 28 404 8.0E-114 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 Gene3D G3DSA:3.90.190.20 280 405 3.3E-27 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 PANTHER PTHR11136:SF0 28 404 8.0E-114 T 22-04-2016 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 49 72 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 SUPERFAMILY SSF53623 1 272 1.7E-83 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS06375 d0562f608ab4f917794dd738fe8ec763 405 SUPERFAMILY SSF53244 279 405 2.75E-22 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS09255 f80891e7d485dff3a54413c7e52d727b 422 Pfam PF01943 Polysaccharide biosynthesis protein 19 282 1.7E-43 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 Gene3D G3DSA:3.30.420.40 9 167 5.2E-43 T 22-04-2016 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 ProSitePatterns PS01016 Glycoprotease family signature. 101 121 - T 22-04-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 SUPERFAMILY SSF53067 9 316 6.29E-38 T 22-04-2016 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PANTHER PTHR11735 1 346 8.2E-133 T 22-04-2016 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PANTHER PTHR11735:SF6 1 346 8.2E-133 T 22-04-2016 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 11 317 5.8E-103 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 10 324 9.5E-121 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 8 346 59.259 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 139 151 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 121 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 162 183 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 11 24 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 81 101 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 2.3E-44 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS01040 c7ffae259a36deecfc8209f4ad1054ca 346 Pfam PF00814 Glycoprotease family 29 317 5.2E-94 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 Gene3D G3DSA:3.10.290.10 64 127 2.5E-26 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 PANTHER PTHR21600:SF2 53 295 1.9E-65 T 22-04-2016 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 SMART SM00363 65 127 4.7E-12 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 SUPERFAMILY SSF55120 124 290 3.52E-26 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 SUPERFAMILY SSF55174 65 119 4.71E-15 T 22-04-2016 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 Pfam PF01479 S4 domain 65 111 9.9E-12 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 PANTHER PTHR21600 53 295 1.9E-65 T 22-04-2016 MED134_RS11075 e2971bc5c6412f030b72dd6ba4a0bebe 296 Pfam PF00849 RNA pseudouridylate synthase 125 203 1.2E-11 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS10770 973fd3ef7df04a24dc56066cd0f851cf 351 Gene3D G3DSA:3.40.50.2000 215 328 1.2E-12 T 22-04-2016 MED134_RS10770 973fd3ef7df04a24dc56066cd0f851cf 351 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 217 329 1.3E-8 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS10770 973fd3ef7df04a24dc56066cd0f851cf 351 Pfam PF13528 Glycosyl transferase family 1 15 130 4.4E-7 T 22-04-2016 MED134_RS10770 973fd3ef7df04a24dc56066cd0f851cf 351 SUPERFAMILY SSF53756 5 330 3.45E-27 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 6.2E-29 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 PANTHER PTHR10909 1 379 1.4E-175 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 SUPERFAMILY SSF47203 229 379 1.58E-56 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Gene3D G3DSA:2.40.110.10 121 216 7.1E-41 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 PANTHER PTHR10909:SF10 1 379 1.4E-175 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Gene3D G3DSA:1.20.140.10 217 379 2.3E-71 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Gene3D G3DSA:1.10.540.10 1 119 2.2E-40 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 377 9.9E-50 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 PIRSF PIRSF016578 6 367 8.2E-20 T 22-04-2016 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 4.0E-35 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS06410 f61207601b596338e01c556ae4b3eaff 380 SUPERFAMILY SSF56645 1 242 5.5E-87 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MED134_RS05840 d8c44afe1c518f5789ca22fbe489869a 216 Pfam PF02666 Phosphatidylserine decarboxylase 48 213 4.2E-27 T 22-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 MED134_RS05840 d8c44afe1c518f5789ca22fbe489869a 216 PANTHER PTHR35809 1 216 1.2E-62 T 22-04-2016 MED134_RS05840 d8c44afe1c518f5789ca22fbe489869a 216 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 4 214 3.8E-49 T 22-04-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 MED134_RS01615 8eef0dc564cd033a827b2117c0165416 376 PANTHER PTHR11177 129 371 7.5E-56 T 22-04-2016 MED134_RS01615 8eef0dc564cd033a827b2117c0165416 376 SUPERFAMILY SSF53474 205 372 1.26E-21 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01615 8eef0dc564cd033a827b2117c0165416 376 SUPERFAMILY SSF53474 78 169 1.26E-21 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01615 8eef0dc564cd033a827b2117c0165416 376 Gene3D G3DSA:3.40.50.1820 39 375 3.9E-91 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01615 8eef0dc564cd033a827b2117c0165416 376 PANTHER PTHR11177:SF162 129 371 7.5E-56 T 22-04-2016 MED134_RS14480 e1e56b4231acb42822a5b47542b54455 206 Gene3D G3DSA:3.40.50.620 3 186 3.4E-29 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS14480 e1e56b4231acb42822a5b47542b54455 206 SUPERFAMILY SSF52402 6 188 4.4E-33 T 22-04-2016 MED134_RS14480 e1e56b4231acb42822a5b47542b54455 206 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 45 185 1.2E-14 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 MED134_RS14480 e1e56b4231acb42822a5b47542b54455 206 PANTHER PTHR23293 7 185 1.2E-20 T 22-04-2016 MED134_RS14480 e1e56b4231acb42822a5b47542b54455 206 PANTHER PTHR23293:SF5 7 185 1.2E-20 T 22-04-2016 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 322 3.6E-81 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PANTHER PTHR10055 1 323 3.2E-112 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 Pfam PF00579 tRNA synthetases class I (W and Y) 3 276 5.7E-57 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PANTHER PTHR10055:SF11 1 323 3.2E-112 T 22-04-2016 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 SUPERFAMILY SSF52374 2 322 5.63E-79 T 22-04-2016 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 Gene3D G3DSA:1.10.240.10 202 291 5.9E-28 T 22-04-2016 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 Gene3D G3DSA:3.40.50.620 3 201 4.7E-71 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 1.1E-20 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 1.1E-20 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 141 162 1.1E-20 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS08820 f6d25058cec1ff91033915c6beba14c2 323 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 1.1E-20 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 6 492 7.8E-164 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Gene3D G3DSA:3.40.50.800 296 415 5.2E-42 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 SUPERFAMILY SSF55681 10 289 6.72E-73 T 22-04-2016 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 115 283 4.0E-18 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 SUPERFAMILY SSF64586 420 492 5.69E-21 T 22-04-2016 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 492 43.566 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Pfam PF03129 Anticodon binding domain 302 397 1.7E-18 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 425 492 1.4E-22 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 SUPERFAMILY SSF52954 291 418 8.83E-35 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Gene3D G3DSA:3.30.110.30 419 491 9.9E-29 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 PANTHER PTHR11451:SF6 9 96 3.8E-230 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 PANTHER PTHR11451:SF6 112 466 3.8E-230 T 22-04-2016 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 SMART SM00946 425 492 3.3E-31 T 22-04-2016 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 PANTHER PTHR11451 9 96 3.8E-230 T 22-04-2016 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 PANTHER PTHR11451 112 466 3.8E-230 T 22-04-2016 MED134_RS13950 179b10c3380e7d0ea475487c43f6bb1a 492 Gene3D G3DSA:3.30.930.10 4 295 2.6E-109 T 22-04-2016 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 Gene3D G3DSA:3.40.50.720 1 180 7.9E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 PANTHER PTHR10366:SF39 2 335 5.1E-123 T 22-04-2016 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 PRINTS PR01713 Nucleotide sugar epimerase signature 260 275 3.8E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 PRINTS PR01713 Nucleotide sugar epimerase signature 299 316 3.8E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 PRINTS PR01713 Nucleotide sugar epimerase signature 232 247 3.8E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 Gene3D G3DSA:3.90.25.10 268 336 1.3E-45 T 22-04-2016 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 Gene3D G3DSA:3.90.25.10 181 233 1.3E-45 T 22-04-2016 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 337 3.4E-119 T 22-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 SUPERFAMILY SSF51735 1 335 5.03E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 327 5.6E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11855 c5e0f5d2611de9bfae3627d715cec710 340 PANTHER PTHR10366 2 335 5.1E-123 T 22-04-2016 MED134_RS07055 bf11d9c6a2c55721f9f88ddb0306816a 128 Pfam PF04379 Protein of unknown function (DUF525) 24 104 2.5E-32 T 22-04-2016 IPR007474 ApaG domain MED134_RS07055 bf11d9c6a2c55721f9f88ddb0306816a 128 Gene3D G3DSA:2.60.40.1470 3 126 1.7E-41 T 22-04-2016 IPR007474 ApaG domain MED134_RS07055 bf11d9c6a2c55721f9f88ddb0306816a 128 PANTHER PTHR14289 5 124 4.6E-35 T 22-04-2016 MED134_RS07055 bf11d9c6a2c55721f9f88ddb0306816a 128 SUPERFAMILY SSF110069 5 127 6.15E-42 T 22-04-2016 IPR007474 ApaG domain MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 213 19.675 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Gene3D G3DSA:3.40.1190.20 235 501 7.0E-80 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 22-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Gene3D G3DSA:3.40.50.10260 1 234 1.5E-52 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 228 498 1.3E-61 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Pfam PF03853 YjeF-related protein N-terminus 26 191 2.2E-35 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 SUPERFAMILY SSF53613 227 499 8.26E-71 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 PANTHER PTHR12592 1 507 1.9E-116 T 22-04-2016 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Pfam PF01256 Carbohydrate kinase 252 486 3.6E-52 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 228 503 22.758 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 PIRSF PIRSF017184 1 506 1.3E-143 T 22-04-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 PANTHER PTHR12592:SF0 1 507 1.9E-116 T 22-04-2016 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 7 201 1.4E-30 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MED134_RS03020 1ae7cdad23477453d636c41db8195b3f 515 SUPERFAMILY SSF64153 9 222 1.96E-49 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 PANTHER PTHR24423 308 548 1.1E-54 T 22-04-2016 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 Gene3D G3DSA:3.30.565.10 394 549 3.4E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 SMART SM00388 327 393 5.8E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 Gene3D G3DSA:1.10.287.130 319 389 3.7E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 SUPERFAMILY SSF47384 316 394 1.12E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 Pfam PF00512 His Kinase A (phospho-acceptor) domain 328 393 3.0E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 SUPERFAMILY SSF55874 382 548 3.8E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 SMART SM00387 438 550 1.2E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 1.9E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 1.9E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 489 1.9E-10 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08940 71c204ee64d5934b72284642b6b2d280 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 439 549 1.3E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 SMART SM00535 34 166 2.9E-29 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 Pfam PF14622 Ribonuclease-III-like 34 158 1.9E-24 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 Gene3D G3DSA:3.30.160.20 172 235 4.6E-13 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 SUPERFAMILY SSF54768 126 238 7.07E-18 T 22-04-2016 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 23 234 6.3E-51 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 PANTHER PTHR11207 21 234 7.7E-38 T 22-04-2016 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 SMART SM00358 173 239 1.9E-7 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 Pfam PF00035 Double-stranded RNA binding motif 173 234 1.5E-11 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 SUPERFAMILY SSF69065 19 158 3.14E-38 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 22 235 23.33 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 MED134_RS08945 f93f0a544a9263b867c96e7d7dc39003 245 Gene3D G3DSA:1.10.1520.10 21 162 1.9E-36 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 9 494 34.827 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 Gene3D G3DSA:3.40.50.620 30 334 9.5E-92 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 SUPERFAMILY SSF52374 8 340 1.1E-78 T 22-04-2016 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 9 491 2.8E-135 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 Gene3D G3DSA:1.20.120.640 336 430 1.5E-15 T 22-04-2016 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 212 230 5.8E-25 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 243 264 5.8E-25 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 68 77 5.8E-25 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 32 43 5.8E-25 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 SUPERFAMILY SSF47323 363 492 9.55E-31 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 23 340 2.9E-95 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 Pfam PF09190 DALR domain 376 434 4.4E-10 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 PANTHER PTHR10890 1 490 1.9E-179 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MED134_RS05050 a346d883e254c7602f0bec4e12b80dc1 494 SMART SM00840 374 437 1.3E-10 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Gene3D G3DSA:3.40.1360.10 241 361 1.8E-43 T 22-04-2016 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 TIGRFAM TIGR01391 dnaG: DNA primase 2 414 1.2E-129 T 22-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Pfam PF10410 DnaB-helicase binding domain of primase 380 420 6.9E-6 T 22-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 251 6.0E-38 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal MED134_RS12450 9810226e867afdc3035dc1083e070033 659 SMART SM00400 33 87 2.9E-16 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 PIRSF PIRSF002811 1 652 4.7E-141 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Pfam PF13662 Toprim domain 262 334 6.8E-17 T 22-04-2016 IPR006171 Toprim domain MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Gene3D G3DSA:3.90.580.10 2 98 1.1E-31 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 SUPERFAMILY SSF57783 2 98 6.8E-28 T 22-04-2016 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 SUPERFAMILY SSF56731 113 421 2.88E-90 T 22-04-2016 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Hamap MF_00974 DNA primase [dnaG]. 1 647 25.158 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Pfam PF01807 CHC2 zinc finger 3 97 4.9E-27 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 SMART SM00493 259 330 7.2E-15 T 22-04-2016 IPR006171 Toprim domain MED134_RS12450 9810226e867afdc3035dc1083e070033 659 PANTHER PTHR30313 1 648 3.4E-128 T 22-04-2016 MED134_RS12450 9810226e867afdc3035dc1083e070033 659 Gene3D G3DSA:3.90.980.10 113 240 3.0E-37 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal MED134_RS00450 8cf80b132c60c2ada1fe12390a06af5a 195 PANTHER PTHR13696 2 173 7.2E-16 T 22-04-2016 MED134_RS00450 8cf80b132c60c2ada1fe12390a06af5a 195 PIRSF PIRSF009320 2 193 2.1E-25 T 22-04-2016 MED134_RS00450 8cf80b132c60c2ada1fe12390a06af5a 195 Gene3D G3DSA:3.40.50.300 3 189 5.7E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00450 8cf80b132c60c2ada1fe12390a06af5a 195 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 154 4.0E-19 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MED134_RS00450 8cf80b132c60c2ada1fe12390a06af5a 195 SUPERFAMILY SSF52540 3 172 3.13E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 Pfam PF03641 Possible lysine decarboxylase 83 214 2.4E-32 T 22-04-2016 IPR031100 LOG family MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 41 218 5.4E-45 T 22-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 Gene3D G3DSA:3.40.50.450 21 224 2.0E-68 T 22-04-2016 MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 SUPERFAMILY SSF102405 11 217 4.27E-61 T 22-04-2016 MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 PANTHER PTHR31223:SF1 10 226 6.1E-102 T 22-04-2016 MED134_RS01935 9fbca0ca125e1cb04f04c7b61785b21e 229 PANTHER PTHR31223 10 226 6.1E-102 T 22-04-2016 MED134_RS00255 ae1c2cef407bd9f6a1d0440e2f9bdc88 1099 PANTHER PTHR30071:SF5 781 1095 5.9E-61 T 22-04-2016 MED134_RS00255 ae1c2cef407bd9f6a1d0440e2f9bdc88 1099 PANTHER PTHR30071 781 1095 5.9E-61 T 22-04-2016 MED134_RS00255 ae1c2cef407bd9f6a1d0440e2f9bdc88 1099 Pfam PF05140 ResB-like family 356 423 5.4E-11 T 22-04-2016 IPR007816 ResB-like domain MED134_RS00255 ae1c2cef407bd9f6a1d0440e2f9bdc88 1099 Pfam PF01578 Cytochrome C assembly protein 854 1058 1.7E-36 T 22-04-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 SUPERFAMILY SSF48452 475 537 9.49E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 Gene3D G3DSA:3.90.226.10 246 427 1.7E-14 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 Gene3D G3DSA:1.25.40.10 488 542 3.7E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 SUPERFAMILY SSF52096 30 122 7.79E-24 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 SUPERFAMILY SSF52096 247 422 7.79E-24 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS01625 2454efbf2a7a964ee54535a98c43983d 551 SMART SM00028 502 535 0.0019 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PANTHER PTHR22855:SF42 1 315 5.3E-116 T 22-04-2016 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 9.1E-42 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 PANTHER PTHR22855 1 315 5.3E-116 T 22-04-2016 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 315 5.4E-133 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 147 7.4E-61 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 SUPERFAMILY SSF52096 4 315 4.4E-91 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 Gene3D G3DSA:3.90.226.10 53 270 6.6E-46 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS05760 88626abcadf73eca21e9e460c16b7df5 317 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 3 315 45.97 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 PANTHER PTHR10804:SF17 11 429 1.0E-104 T 22-04-2016 MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 PANTHER PTHR10804 11 429 1.0E-104 T 22-04-2016 MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 SMART SM01011 6 142 1.7E-35 T 22-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 SUPERFAMILY SSF55920 181 429 1.57E-67 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 Pfam PF00557 Metallopeptidase family M24 186 406 7.3E-56 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 Gene3D G3DSA:3.90.230.10 184 429 5.6E-73 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 Gene3D G3DSA:3.40.350.10 6 183 7.6E-40 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 SUPERFAMILY SSF53092 5 179 1.1E-42 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal MED134_RS10980 a99c863ef5b107f76b3bba588918de19 430 Pfam PF05195 Aminopeptidase P, N-terminal domain 11 132 2.7E-29 T 22-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PANTHER PTHR23115 5 181 2.1E-218 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PANTHER PTHR23115 248 466 2.1E-218 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 514 2.0E-43 T 22-04-2016 IPR032090 Peptide chain release factor 3, C-terminal MED134_RS14580 a9fff75185a531660313beff097182ac 530 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.4E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.4E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.4E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.4E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.4E-12 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 Gene3D G3DSA:3.30.70.870 391 461 1.1E-8 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 526 8.2E-200 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 MED134_RS14580 a9fff75185a531660313beff097182ac 530 Gene3D G3DSA:3.40.50.300 5 277 1.0E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14580 a9fff75185a531660313beff097182ac 530 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 150 8.3E-27 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS14580 a9fff75185a531660313beff097182ac 530 SUPERFAMILY SSF54980 390 465 9.71E-14 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS14580 a9fff75185a531660313beff097182ac 530 Gene3D G3DSA:2.40.30.10 290 390 7.9E-17 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 SUPERFAMILY SSF52540 6 274 1.95E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14580 a9fff75185a531660313beff097182ac 530 Pfam PF00009 Elongation factor Tu GTP binding domain 10 274 1.3E-51 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site MED134_RS14580 a9fff75185a531660313beff097182ac 530 PANTHER PTHR23115:SF69 5 181 2.1E-218 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 PANTHER PTHR23115:SF69 248 466 2.1E-218 T 22-04-2016 MED134_RS14580 a9fff75185a531660313beff097182ac 530 SUPERFAMILY SSF50447 258 389 5.44E-24 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS14580 a9fff75185a531660313beff097182ac 530 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 526 49.915 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 SUPERFAMILY SSF49464 14 110 1.28E-13 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 PANTHER PTHR11532 1 104 2.0E-13 T 22-04-2016 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 Gene3D G3DSA:2.60.40.1120 14 112 2.5E-12 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 Pfam PF13715 CarboxypepD_reg-like domain 15 104 8.6E-16 T 22-04-2016 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 Gene3D G3DSA:2.40.170.20 205 768 1.0E-24 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 Pfam PF14905 Outer membrane protein beta-barrel family 364 766 7.1E-82 T 22-04-2016 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 PANTHER PTHR11532:SF57 1 104 2.0E-13 T 22-04-2016 MED134_RS06745 8087bc7ee5aafa5915b289dde3abe4e4 790 SUPERFAMILY SSF56935 101 768 1.53E-49 T 22-04-2016 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 SUPERFAMILY SSF52922 457 578 2.62E-21 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Pfam PF02779 Transketolase, pyrimidine binding domain 284 444 1.9E-32 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Gene3D G3DSA:3.40.50.970 263 460 5.2E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 PANTHER PTHR11624 19 579 2.4E-257 T 22-04-2016 IPR033247 Transketolase family MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 SUPERFAMILY SSF52518 5 346 5.42E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Pfam PF02780 Transketolase, C-terminal domain 465 578 3.1E-18 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 SUPERFAMILY SSF52518 274 450 1.99E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 587 38.977 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Gene3D G3DSA:3.40.50.920 461 578 6.7E-22 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 SMART SM00861 284 449 1.2E-58 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 PANTHER PTHR11624:SF20 19 579 2.4E-257 T 22-04-2016 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 198 4.6E-86 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 MED134_RS11045 dd62f07b57b022194fedd9e852a8f5a7 587 Gene3D G3DSA:3.40.50.970 6 262 6.0E-58 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 SUPERFAMILY SSF111369 57 294 3.01E-13 T 22-04-2016 MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 PANTHER PTHR30469 1 377 7.8E-22 T 22-04-2016 MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 Gene3D G3DSA:2.40.50.100 187 220 2.1E-12 T 22-04-2016 MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 Gene3D G3DSA:2.40.50.100 68 102 2.1E-12 T 22-04-2016 MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 Pfam PF13437 HlyD family secretion protein 190 282 3.5E-15 T 22-04-2016 MED134_RS06065 faf92e20086b433aaf5ff6287dd55ff2 378 PANTHER PTHR30469:SF15 1 377 7.8E-22 T 22-04-2016 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Pfam PF01808 AICARFT/IMPCHase bienzyme 138 441 5.1E-102 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 SUPERFAMILY SSF52335 7 197 1.31E-58 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Gene3D G3DSA:3.40.140.20 236 352 9.3E-42 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 SUPERFAMILY SSF53927 212 510 7.72E-111 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Gene3D G3DSA:3.40.140.20 357 500 8.5E-50 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 510 37.631 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 10 510 5.7E-160 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Gene3D G3DSA:3.40.50.1380 5 191 6.2E-67 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 SMART SM00798 138 442 6.1E-146 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 SMART SM00851 19 133 5.1E-43 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 PANTHER PTHR11692 5 510 1.0E-241 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 Pfam PF02142 MGS-like domain 19 132 7.2E-22 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 PANTHER PTHR11692:SF2 5 510 1.0E-241 T 22-04-2016 MED134_RS06225 6b4637ca73a459e83a647cb6a8aed8a8 510 PIRSF PIRSF000414 1 510 9.7E-189 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 MED134_RS12400 e493accb2fe27d073f491615637843a1 135 Gene3D G3DSA:3.30.70.900 32 134 1.9E-36 T 22-04-2016 MED134_RS12400 e493accb2fe27d073f491615637843a1 135 PANTHER PTHR33178 26 132 2.6E-30 T 22-04-2016 MED134_RS12400 e493accb2fe27d073f491615637843a1 135 SMART SM00886 38 134 6.6E-26 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel MED134_RS12400 e493accb2fe27d073f491615637843a1 135 Pfam PF07876 Stress responsive A/B Barrel Domain 38 133 2.4E-28 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel MED134_RS12400 e493accb2fe27d073f491615637843a1 135 PANTHER PTHR33178:SF2 26 132 2.6E-30 T 22-04-2016 MED134_RS12400 e493accb2fe27d073f491615637843a1 135 SUPERFAMILY SSF54909 38 133 3.22E-26 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 Gene3D G3DSA:2.170.120.20 96 186 9.8E-26 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 176 6.4E-40 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 Pfam PF01386 Ribosomal L25p family 6 90 2.4E-27 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 24.274 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 18 93 1.0E-20 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 179 8.3E-24 T 22-04-2016 IPR020057 Ribosomal protein L25, beta domain MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 PANTHER PTHR33284 5 208 1.6E-47 T 22-04-2016 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 SUPERFAMILY SSF50715 10 179 1.73E-52 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 MED134_RS08300 2ea55923681bb7ab4cc10334334f96e3 208 Gene3D G3DSA:2.40.240.10 4 93 5.9E-29 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 PANTHER PTHR20852:SF14 1 331 2.8E-156 T 22-04-2016 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 SUPERFAMILY SSF55931 96 330 2.35E-57 T 22-04-2016 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 SMART SM01230 87 331 7.5E-43 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 216 232 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 ProSitePatterns PS00180 Glutamine synthetase signature 1. 42 59 - T 22-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 81 4.0E-14 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 SUPERFAMILY SSF54368 7 89 2.28E-9 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 PANTHER PTHR20852 1 331 2.8E-156 T 22-04-2016 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 Pfam PF00120 Glutamine synthetase, catalytic domain 95 323 2.2E-17 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MED134_RS03835 73d1476c501da8508c401857dd426b63 336 Gene3D G3DSA:3.30.590.10 95 328 5.3E-53 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 MED134_RS07880 7874dff2d31f5db608671ec8ec1099df 170 Pfam PF00925 GTP cyclohydrolase II 6 164 3.0E-39 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 MED134_RS07880 7874dff2d31f5db608671ec8ec1099df 170 SUPERFAMILY SSF142695 2 168 2.35E-42 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 MED134_RS07880 7874dff2d31f5db608671ec8ec1099df 170 PANTHER PTHR21327:SF6 1 169 2.7E-35 T 22-04-2016 MED134_RS07880 7874dff2d31f5db608671ec8ec1099df 170 PANTHER PTHR21327 1 169 2.7E-35 T 22-04-2016 MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 SUPERFAMILY SSF82171 166 317 1.18E-7 T 22-04-2016 MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 Pfam PF13585 C-terminal domain of CHU protein family 798 868 2.0E-16 T 22-04-2016 MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 Gene3D G3DSA:2.120.10.30 204 297 1.3E-4 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 Gene3D G3DSA:2.60.40.670 389 452 3.4E-10 T 22-04-2016 IPR000601 PKD domain MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 797 877 3.5E-30 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS03475 15ab0910d1d0e76e167851104c3ebb49 882 SUPERFAMILY SSF49299 385 451 3.14E-11 T 22-04-2016 IPR000601 PKD domain MED134_RS04255 c50f1a8081559dcf48f17cfac16ebfe8 324 Pfam PF04018 Domain of unknown function (DUF368) 18 275 5.4E-92 T 22-04-2016 IPR007163 Protein of unknown function DUF368 MED134_RS04255 c50f1a8081559dcf48f17cfac16ebfe8 324 PANTHER PTHR37308 2 318 2.3E-68 T 22-04-2016 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 8.9E-67 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 PANTHER PTHR21139 1 248 2.3E-121 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 Gene3D G3DSA:3.20.20.70 1 249 1.5E-105 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 39.715 T 22-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 SUPERFAMILY SSF51351 1 248 1.96E-95 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 22-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS13520 f7b375e1db75854f73bba23d1330f9d9 250 Pfam PF00121 Triosephosphate isomerase 5 246 1.8E-94 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 MED134_RS12525 d8018bd31018a6a3159a1549ec6c87ef 402 Pfam PF01098 Cell cycle protein 17 382 7.6E-71 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS12525 d8018bd31018a6a3159a1549ec6c87ef 402 PANTHER PTHR30474:SF2 15 399 2.6E-93 T 22-04-2016 MED134_RS12525 d8018bd31018a6a3159a1549ec6c87ef 402 PANTHER PTHR30474 15 399 2.6E-93 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 Pfam PF08281 Sigma-70, region 4 131 169 5.3E-11 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 Gene3D G3DSA:1.10.10.10 122 185 1.2E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 Gene3D G3DSA:1.10.1740.10 7 104 4.9E-26 T 22-04-2016 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 183 9.5E-29 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 PANTHER PTHR30173 1 186 7.6E-42 T 22-04-2016 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 SUPERFAMILY SSF88659 118 185 1.87E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 SUPERFAMILY SSF88946 7 100 1.69E-23 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS02070 335c43f6886cae5e82981f3c996d9dd9 194 Pfam PF04542 Sigma-70 region 2 26 95 1.8E-14 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 70 193 1.8E-18 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 2.2E-14 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 2.2E-14 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 183 196 2.2E-14 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 176 2.2E-14 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 6 200 2.7E-51 T 22-04-2016 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 7 185 6.7E-16 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 Gene3D G3DSA:3.40.50.1000 85 221 7.2E-36 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PANTHER PTHR12725 9 223 4.0E-47 T 22-04-2016 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 PANTHER PTHR12725:SF66 9 223 4.0E-47 T 22-04-2016 MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 SUPERFAMILY SSF56784 1 218 4.77E-44 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08580 81ea3b366ab8b18fef2229744d636059 223 Gene3D G3DSA:1.10.150.240 30 84 1.3E-4 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 Pfam PF00313 'Cold-shock' DNA-binding domain 20 79 1.4E-19 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 SUPERFAMILY SSF50249 16 79 1.18E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 PANTHER PTHR11544 21 77 1.1E-15 T 22-04-2016 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 ProSitePatterns PS00352 'Cold-shock' domain signature. 32 51 - T 22-04-2016 IPR019844 Cold-shock conserved site MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 SMART SM00357 20 80 2.8E-15 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 PRINTS PR00050 Cold shock protein signature 53 71 2.5E-8 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 PRINTS PR00050 Cold shock protein signature 21 36 2.5E-8 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01580 79810bbf2d3c03f59c015f4cf37925ac 82 Gene3D G3DSA:2.40.50.140 19 81 5.7E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 PANTHER PTHR30026 346 477 1.6E-49 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 PANTHER PTHR30026 1 302 1.6E-49 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 SUPERFAMILY SSF56954 350 479 1.74E-78 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 SUPERFAMILY SSF56954 1 301 1.74E-78 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 Pfam PF02321 Outer membrane efflux protein 26 217 4.0E-17 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 Pfam PF02321 Outer membrane efflux protein 246 467 3.6E-36 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 PANTHER PTHR30026:SF4 346 477 1.6E-49 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 PANTHER PTHR30026:SF4 1 302 1.6E-49 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 Gene3D G3DSA:1.20.1600.10 20 294 3.0E-78 T 22-04-2016 MED134_RS11395 af2d5ab5e30f8c8bc52aa126d3dfcf62 485 Gene3D G3DSA:1.20.1600.10 345 478 3.0E-78 T 22-04-2016 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 PANTHER PTHR12903 3 103 4.4E-40 T 22-04-2016 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 SMART SM00739 5 32 1.3E-5 T 22-04-2016 IPR005824 KOW MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 7.2E-37 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 Gene3D G3DSA:2.30.30.30 2 92 4.5E-26 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 9 26 - T 22-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 Pfam PF00467 KOW motif 9 39 1.3E-8 T 22-04-2016 IPR005824 KOW MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 SUPERFAMILY SSF50104 2 102 2.49E-34 T 22-04-2016 IPR008991 Translation protein SH3-like domain MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 41 102 2.7E-25 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12290 83e4a1a0e2c037c9359b11ede3b457aa 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 4 97 20.831 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 6 489 1.7E-191 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 485 1.7E-112 T 22-04-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 6 489 82.739 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 3.4E-45 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 331 357 3.4E-45 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 3.4E-45 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 3.4E-45 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 3.4E-45 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 10 189 2.8E-59 T 22-04-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 Gene3D G3DSA:3.40.50.720 4 188 4.3E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PANTHER PTHR23429:SF0 1 497 5.4E-218 T 22-04-2016 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 SUPERFAMILY SSF55347 179 487 3.6E-112 T 22-04-2016 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PIRSF PIRSF000110 1 491 8.5E-179 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 SUPERFAMILY SSF51735 3 192 2.76E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 22-04-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 PANTHER PTHR23429 1 497 5.4E-218 T 22-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 MED134_RS14025 01b5f75fffd7032097d1ca4efb21dcc2 504 Gene3D G3DSA:3.30.360.10 189 485 5.4E-118 T 22-04-2016 MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 Gene3D G3DSA:3.40.50.720 3 241 3.4E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 SUPERFAMILY SSF51735 1 291 6.76E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 PANTHER PTHR11092 1 302 1.6E-83 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 216 9.1E-12 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 Pfam PF08338 Domain of unknown function (DUF1731) 260 300 1.9E-11 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 5 298 4.0E-78 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 MED134_RS11990 304a164842b140bc1a3d99dd4b847c5c 303 PANTHER PTHR11092:SF0 1 302 1.6E-83 T 22-04-2016 MED134_RS14510 f5af2ce5515f227abfae1a442ca35023 444 Pfam PF06580 Histidine kinase 160 238 3.9E-25 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MED134_RS14510 f5af2ce5515f227abfae1a442ca35023 444 PANTHER PTHR34220:SF1 16 345 1.0E-57 T 22-04-2016 MED134_RS14510 f5af2ce5515f227abfae1a442ca35023 444 PANTHER PTHR34220 16 345 1.0E-57 T 22-04-2016 MED134_RS14510 f5af2ce5515f227abfae1a442ca35023 444 Pfam PF13239 2TM domain 362 440 9.9E-25 T 22-04-2016 IPR025698 2TM domain MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 PIRSF PIRSF002599 1 64 2.5E-16 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 33 - T 22-04-2016 IPR019844 Cold-shock conserved site MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 SUPERFAMILY SSF50249 2 62 6.0E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 Gene3D G3DSA:2.40.50.140 1 63 1.6E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 Pfam PF00313 'Cold-shock' DNA-binding domain 1 62 6.8E-21 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 PANTHER PTHR11544 1 63 5.2E-16 T 22-04-2016 MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 SMART SM00357 2 63 7.9E-18 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 PRINTS PR00050 Cold shock protein signature 36 54 3.2E-9 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS10690 b07b522bc6c4f0e593e46e3482f5ce01 64 PRINTS PR00050 Cold shock protein signature 3 18 3.2E-9 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 SUPERFAMILY SSF52161 10 148 2.35E-57 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 Gene3D G3DSA:3.90.1180.10 9 145 3.0E-62 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 10 145 1.1E-56 T 22-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 PIRSF PIRSF002181 4 150 3.0E-51 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 Pfam PF00572 Ribosomal protein L13 19 142 4.1E-55 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 PANTHER PTHR11545 5 142 6.9E-70 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MED134_RS06795 5410110bcc41b2ea81ae1c6487142851 151 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 20 148 28.444 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MED134_RS05090 dd6e6507797ce44f9094710836a1d209 204 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 3 184 5.1E-43 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS05090 dd6e6507797ce44f9094710836a1d209 204 PANTHER PTHR11820 2 204 3.1E-71 T 22-04-2016 MED134_RS05090 dd6e6507797ce44f9094710836a1d209 204 PANTHER PTHR11820:SF7 2 204 3.1E-71 T 22-04-2016 MED134_RS05090 dd6e6507797ce44f9094710836a1d209 204 SUPERFAMILY SSF56529 2 203 2.09E-60 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS05090 dd6e6507797ce44f9094710836a1d209 204 Gene3D G3DSA:3.90.850.10 2 203 1.1E-66 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 PANTHER PTHR11059 2 549 6.5E-138 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 SUPERFAMILY SSF52540 2 216 1.54E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 Gene3D G3DSA:3.40.50.300 2 205 8.4E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 508 8.7E-17 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 PIRSF PIRSF003128 1 550 1.4E-160 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 SUPERFAMILY SSF52540 3 50 8.8E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 SUPERFAMILY SSF52540 282 501 8.8E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 550 6.9E-146 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 Gene3D G3DSA:3.40.50.300 344 345 1.2E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05195 5340f766fe0622d901fc8a04c47633f9 550 Gene3D G3DSA:3.40.50.300 387 497 1.2E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 SUPERFAMILY SSF52540 73 356 3.95E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 Pfam PF00271 Helicase conserved C-terminal domain 229 338 5.5E-28 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 PANTHER PTHR24031 3 410 7.5E-140 T 22-04-2016 MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 SMART SM00487 22 221 1.3E-50 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 Pfam PF00270 DEAD/DEAH box helicase 27 194 2.3E-43 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 Gene3D G3DSA:3.40.50.300 3 217 1.6E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 Gene3D G3DSA:3.40.50.300 218 369 1.8E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01555 931afd217e3ec95c574fd3f3205ca481 428 SMART SM00490 257 338 2.2E-28 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS03150 d230d9d7268af457997252498fc33a37 238 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 2 229 4.4E-89 T 22-04-2016 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 MED134_RS03150 d230d9d7268af457997252498fc33a37 238 SUPERFAMILY SSF102588 3 234 1.57E-47 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain MED134_RS03150 d230d9d7268af457997252498fc33a37 238 PANTHER PTHR12993 1 185 2.2E-31 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related MED134_RS03150 d230d9d7268af457997252498fc33a37 238 Gene3D G3DSA:3.40.50.10320 2 233 3.3E-59 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain MED134_RS03150 d230d9d7268af457997252498fc33a37 238 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 122 5.4E-19 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related MED134_RS04090 1d2b456fc83eb9da1bd1649c80a76f91 82 PANTHER PTHR36582 1 80 5.2E-26 T 22-04-2016 MED134_RS04090 1d2b456fc83eb9da1bd1649c80a76f91 82 SUPERFAMILY SSF47598 1 44 3.0E-8 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 MED134_RS04090 1d2b456fc83eb9da1bd1649c80a76f91 82 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 2 78 2.3E-26 T 22-04-2016 IPR022789 Antitoxin ParD MED134_RS04090 1d2b456fc83eb9da1bd1649c80a76f91 82 PANTHER PTHR36582:SF2 1 80 5.2E-26 T 22-04-2016 MED134_RS04090 1d2b456fc83eb9da1bd1649c80a76f91 82 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 69 1.8E-26 T 22-04-2016 IPR022789 Antitoxin ParD MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 Gene3D G3DSA:3.40.1280.10 100 245 1.4E-37 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 SUPERFAMILY SSF75217 95 245 2.55E-33 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 SUPERFAMILY SSF55315 3 94 1.18E-11 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 PANTHER PTHR12029 7 245 1.8E-42 T 22-04-2016 MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 Gene3D G3DSA:3.30.1330.30 2 94 8.4E-24 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS05500 8433f152535ff6fc70e4036599347b73 246 Pfam PF00588 SpoU rRNA Methylase family 103 240 3.5E-31 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 PIRSF PIRSF004848 1 215 2.3E-67 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 15 215 4.8E-54 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 Pfam PF01168 Alanine racemase, N-terminal domain 3 215 2.2E-22 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 PANTHER PTHR10146 1 215 1.9E-79 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 SUPERFAMILY SSF51419 1 213 1.44E-69 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS05145 616f761b50b7a23a080af62aa2ebc238 215 Gene3D G3DSA:3.20.20.10 2 215 6.0E-75 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Gene3D G3DSA:3.30.70.240 396 476 9.0E-28 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Pfam PF00009 Elongation factor Tu GTP binding domain 2 193 1.3E-54 T 22-04-2016 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 SUPERFAMILY SSF52540 2 199 1.78E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Gene3D G3DSA:3.30.70.870 301 395 8.2E-35 T 22-04-2016 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 SUPERFAMILY SSF50447 150 294 1.17E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 141 4.9E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PANTHER PTHR23115 2 586 4.0E-253 T 22-04-2016 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Gene3D G3DSA:2.40.50.250 479 572 1.9E-37 T 22-04-2016 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 SUPERFAMILY SSF54980 395 508 1.15E-26 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Pfam PF00679 Elongation factor G C-terminus 393 475 6.7E-22 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PANTHER PTHR23115:SF14 2 586 4.0E-253 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 SMART SM00838 392 479 0.0021 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Gene3D G3DSA:3.40.50.300 2 201 2.1E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 594 1.2E-267 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PRINTS PR00315 GTP-binding elongation factor signature 49 57 6.8E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PRINTS PR00315 GTP-binding elongation factor signature 121 130 6.8E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PRINTS PR00315 GTP-binding elongation factor signature 5 18 6.8E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 PRINTS PR00315 GTP-binding elongation factor signature 69 79 6.8E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 SUPERFAMILY SSF54980 299 384 3.79E-14 T 22-04-2016 IPR009022 Elongation factor G, III-V domain MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Gene3D G3DSA:2.40.30.10 202 300 8.7E-25 T 22-04-2016 MED134_RS13590 77720116414700dfd4f0bb7ba8e53569 598 Pfam PF03144 Elongation factor Tu domain 2 216 285 3.4E-13 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 MED134_RS11465 ff2ab3171fef696813647d0d4ccdb4f6 103 Pfam PF00581 Rhodanese-like domain 14 92 2.2E-11 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS11465 ff2ab3171fef696813647d0d4ccdb4f6 103 SUPERFAMILY SSF52821 15 92 2.75E-19 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS11465 ff2ab3171fef696813647d0d4ccdb4f6 103 SMART SM00450 10 100 8.7E-9 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS11465 ff2ab3171fef696813647d0d4ccdb4f6 103 Gene3D G3DSA:3.40.250.10 13 92 1.5E-20 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS01455 6fdbc215959626f6990cb4e44ff6e2fa 451 Pfam PF14052 Capsule assembly protein Wzi 129 388 1.7E-20 T 22-04-2016 IPR026950 Capsule assembly protein Wzi MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 Gene3D G3DSA:3.40.50.720 411 514 7.7E-10 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 PANTHER PTHR32507:SF0 4 518 6.3E-133 T 22-04-2016 MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 SUPERFAMILY SSF51735 412 517 5.8E-11 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 Pfam PF02254 TrkA-N domain 412 500 1.5E-8 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 PANTHER PTHR32507 4 518 6.3E-133 T 22-04-2016 MED134_RS09025 bb0e3f92317f9f10b235b8d97e378b7e 628 Pfam PF00999 Sodium/hydrogen exchanger family 9 397 1.9E-39 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 Pfam PF00005 ABC transporter 392 468 4.6E-7 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 Pfam PF00005 ABC transporter 18 182 4.5E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 SUPERFAMILY SSF52540 228 288 1.73E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 PANTHER PTHR19211 1 539 5.4E-287 T 22-04-2016 MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 PANTHER PTHR19211:SF38 1 539 5.4E-287 T 22-04-2016 MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 Pfam PF12848 ABC transporter 222 303 1.2E-19 T 22-04-2016 IPR032781 ABC-transporter extension domain MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 SMART SM00382 26 229 1.6E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 SUPERFAMILY SSF52540 123 248 6.82E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 SUPERFAMILY SSF52540 2 92 6.82E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 Gene3D G3DSA:3.40.50.300 1 269 4.7E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 Gene3D G3DSA:3.40.50.300 322 534 5.4E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03090 7d1e74ad80b7f2e54b7c68b414a67751 539 SUPERFAMILY SSF52540 383 514 1.73E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02040 b127bd1acbf7082d5a2aae2cb874813b 216 Pfam PF02230 Phospholipase/Carboxylesterase 17 213 8.2E-27 T 22-04-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MED134_RS02040 b127bd1acbf7082d5a2aae2cb874813b 216 PANTHER PTHR10655 16 215 3.1E-35 T 22-04-2016 MED134_RS02040 b127bd1acbf7082d5a2aae2cb874813b 216 Gene3D G3DSA:3.40.50.1820 16 215 1.2E-51 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS02040 b127bd1acbf7082d5a2aae2cb874813b 216 PANTHER PTHR10655:SF17 16 215 3.1E-35 T 22-04-2016 MED134_RS02040 b127bd1acbf7082d5a2aae2cb874813b 216 SUPERFAMILY SSF53474 13 215 3.43E-48 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01170 49148eec9b2d3b7ded952d9369de28e1 415 Gene3D G3DSA:3.40.710.10 180 248 3.8E-13 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01170 49148eec9b2d3b7ded952d9369de28e1 415 Gene3D G3DSA:3.40.710.10 286 399 3.8E-13 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01170 49148eec9b2d3b7ded952d9369de28e1 415 Pfam PF13354 Beta-lactamase enzyme family 111 352 6.5E-7 T 22-04-2016 MED134_RS01170 49148eec9b2d3b7ded952d9369de28e1 415 SUPERFAMILY SSF56601 93 218 4.17E-15 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01170 49148eec9b2d3b7ded952d9369de28e1 415 SUPERFAMILY SSF56601 247 392 4.17E-15 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 PANTHER PTHR22573 1 459 4.6E-133 T 22-04-2016 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 SUPERFAMILY SSF53738 267 371 4.71E-20 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 SUPERFAMILY SSF55957 365 460 1.2E-25 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 142 2.4E-29 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Gene3D G3DSA:3.40.120.10 6 157 1.3E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 171 263 1.1E-23 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 PANTHER PTHR22573:SF48 1 459 4.6E-133 T 22-04-2016 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 270 373 8.5E-19 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 243 258 4.5E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 4.5E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 182 201 4.5E-12 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 SUPERFAMILY SSF53738 170 265 1.26E-23 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 395 456 6.4E-11 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Gene3D G3DSA:3.40.120.10 264 356 4.0E-27 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 4 455 3.3E-160 T 22-04-2016 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Gene3D G3DSA:3.30.310.50 377 459 1.1E-22 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 Gene3D G3DSA:3.40.120.10 184 259 9.8E-24 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS01215 a825e280c8805528492b03d8e9e7f4f5 462 SUPERFAMILY SSF53738 8 188 1.02E-31 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS05480 195a701347ca4139faa110dd4a7f234d 498 PANTHER PTHR32024 3 498 7.2E-185 T 22-04-2016 MED134_RS05480 195a701347ca4139faa110dd4a7f234d 498 Pfam PF02386 Cation transport protein 48 489 3.5E-69 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MED134_RS05480 195a701347ca4139faa110dd4a7f234d 498 PIRSF PIRSF006247 1 497 1.9E-175 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MED134_RS05480 195a701347ca4139faa110dd4a7f234d 498 PANTHER PTHR32024:SF2 3 498 7.2E-185 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.30.54.20 132 186 8.6E-17 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PANTHER PTHR11451:SF5 1 644 2.8E-297 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 SUPERFAMILY SSF55681 242 533 8.3E-94 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.30.980.10 65 130 9.0E-39 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.30.980.10 187 223 9.0E-39 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 332 360 1.5E-50 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 365 388 1.5E-50 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 541 553 1.5E-50 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 499 1.5E-50 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 514 527 1.5E-50 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 SUPERFAMILY SSF55186 63 240 3.92E-58 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Pfam PF02824 TGS domain 2 61 1.4E-13 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 641 33.774 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 535 2.1E-41 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.30.930.10 241 535 3.4E-112 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.40.50.800 538 642 5.5E-29 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 218 8.9E-11 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Pfam PF03129 Anticodon binding domain 548 636 4.6E-20 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 PANTHER PTHR11451 1 644 2.8E-297 T 22-04-2016 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 SUPERFAMILY SSF81271 2 62 1.16E-16 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 SUPERFAMILY SSF52954 536 641 2.42E-27 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 SMART SM00863 169 218 3.3E-20 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 638 7.3E-215 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MED134_RS06305 4b3b7f9652e972e7c33ade43e2454b31 647 Gene3D G3DSA:3.10.20.30 1 64 2.0E-23 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 7.8E-22 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 204 220 7.8E-22 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 7.8E-22 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 7.8E-22 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PANTHER PTHR22912:SF158 1 320 3.7E-90 T 22-04-2016 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 Hamap MF_01685 Ferredoxin--NADP reductase. 3 329 39.991 T 22-04-2016 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 Gene3D G3DSA:3.50.50.60 125 242 1.1E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 288 1.8E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 Gene3D G3DSA:3.50.50.60 246 316 7.9E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 Gene3D G3DSA:3.50.50.60 2 124 7.9E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 SUPERFAMILY SSF51905 1 308 1.41E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PANTHER PTHR22912 1 320 3.7E-90 T 22-04-2016 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 5.5E-14 T 22-04-2016 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.5E-14 T 22-04-2016 MED134_RS10800 e0cc72a43ec7b63ae9932a20ab3dd1d6 350 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.5E-14 T 22-04-2016 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 Pfam PF13439 Glycosyltransferase Family 4 11 177 2.0E-28 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 Pfam PF00534 Glycosyl transferases group 1 192 350 2.4E-37 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 PANTHER PTHR12526:SF336 1 370 1.2E-170 T 22-04-2016 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 Gene3D G3DSA:3.40.50.2000 188 349 3.0E-25 T 22-04-2016 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 SUPERFAMILY SSF53756 6 372 1.03E-81 T 22-04-2016 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 1 372 1.5E-170 T 22-04-2016 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 MED134_RS03575 14e72a5e63d68e725d3f918506569d72 375 PANTHER PTHR12526 1 370 1.2E-170 T 22-04-2016 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 SUPERFAMILY SSF53720 18 494 1.2E-94 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 Gene3D G3DSA:3.40.309.10 259 446 2.8E-46 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 PANTHER PTHR11699:SF10 1 448 2.0E-128 T 22-04-2016 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 Gene3D G3DSA:3.40.605.10 13 258 1.2E-48 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 PANTHER PTHR11699 1 448 2.0E-128 T 22-04-2016 MED134_RS07775 dab233a6c25b0bc8ac74a23aa593d812 498 Pfam PF00171 Aldehyde dehydrogenase family 16 458 4.7E-55 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS06210 a25907ef24397680e57b1f4291564394 182 TIGRFAM TIGR04128 exoso_Fjoh_1448: exosortase family protein XrtF 5 177 3.4E-69 T 22-04-2016 IPR026323 Exosortase-related protein XrtF MED134_RS06210 a25907ef24397680e57b1f4291564394 182 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 46 170 3.6E-10 T 22-04-2016 IPR019127 Exosortase EpsH-related KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS06210 a25907ef24397680e57b1f4291564394 182 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 87 173 3.1E-15 T 22-04-2016 IPR026392 Exosortase/Archaeosortase domain MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 321 334 2.3E-7 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 212 227 2.3E-7 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 293 307 2.3E-7 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 345 357 2.3E-7 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 Gene3D G3DSA:3.40.50.300 190 392 1.0E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 SUPERFAMILY SSF54211 5 166 1.56E-34 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 407 503 1.6E-33 T 22-04-2016 IPR025158 Mg chelatase-related protein, C-terminal domain MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 Gene3D G3DSA:3.30.230.10 4 165 2.5E-33 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PANTHER PTHR32039:SF7 1 507 6.2E-247 T 22-04-2016 IPR004482 Mg chelatase-related protein MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 SUPERFAMILY SSF52540 190 505 2.95E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 PANTHER PTHR32039 1 507 6.2E-247 T 22-04-2016 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 141 1.4E-42 T 22-04-2016 MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 5 503 3.5E-193 T 22-04-2016 IPR004482 Mg chelatase-related protein MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 SMART SM00382 213 396 3.7E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS04780 b57c83631dd0222b107c551dc457e19d 512 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 398 1.7E-92 T 22-04-2016 IPR000523 Magnesium chelatase ChlI domain MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 SMART SM00418 18 100 2.7E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 Gene3D G3DSA:1.10.10.10 4 100 2.6E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 SUPERFAMILY SSF46785 6 100 5.74E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 Pfam PF12840 Helix-turn-helix domain 17 73 1.3E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 6.3E-10 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 6.3E-10 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 6.3E-10 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 PANTHER PTHR33154:SF6 8 109 9.4E-16 T 22-04-2016 MED134_RS08220 f26fbaa888fe2aa02429545812400829 109 PANTHER PTHR33154 8 109 9.4E-16 T 22-04-2016 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 124 22.591 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 SUPERFAMILY SSF48300 3 60 2.22E-12 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 1.8E-13 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 Gene3D G3DSA:3.30.1390.10 52 124 7.3E-32 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 1.1E-38 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 Gene3D G3DSA:1.20.5.710 6 50 7.7E-8 T 22-04-2016 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 102 1.0E-11 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 2.4E-29 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 MED134_RS04890 ff307d61eed3e1ac50dbbcfe64af73ff 124 SUPERFAMILY SSF54736 53 124 9.07E-24 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 PANTHER PTHR22778:SF21 17 321 1.7E-96 T 22-04-2016 MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 Pfam PF00581 Rhodanese-like domain 137 231 4.5E-11 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 Hamap MF_00469 UPF0176 protein YceA [yceA]. 21 276 36.913 T 22-04-2016 IPR020936 Uncharacterised protein family UPF0176 MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 Gene3D G3DSA:3.40.250.10 114 236 2.0E-34 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 SUPERFAMILY SSF52821 119 252 4.12E-27 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 Pfam PF12368 Rhodanase C-terminal 244 306 5.8E-19 T 22-04-2016 IPR022111 Rhodanase, C-terminal MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 PANTHER PTHR22778 17 321 1.7E-96 T 22-04-2016 MED134_RS08795 c764a6ebda089a24a9e0b8b1fe989704 343 SMART SM00450 134 236 1.3E-23 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Gene3D G3DSA:2.40.170.20 225 799 7.3E-30 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 SUPERFAMILY SSF56935 116 799 5.49E-69 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Pfam PF07715 TonB-dependent Receptor Plug Domain 145 224 7.0E-11 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Gene3D G3DSA:2.60.40.1120 29 90 4.1E-10 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Pfam PF14905 Outer membrane protein beta-barrel family 380 797 6.2E-118 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 SUPERFAMILY SSF49464 28 118 2.62E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 PANTHER PTHR32552:SF0 303 799 5.3E-19 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 PANTHER PTHR32552:SF0 97 284 5.3E-19 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Gene3D G3DSA:2.170.130.10 146 224 1.1E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 Pfam PF13620 Carboxypeptidase regulatory-like domain 29 92 1.1E-10 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 PANTHER PTHR32552 303 799 5.3E-19 T 22-04-2016 MED134_RS11360 e55676fc7488e43b3f0853306a5cd842 821 PANTHER PTHR32552 97 284 5.3E-19 T 22-04-2016 MED134_RS09485 e15cf5378fc97be664e434bf8c50223b 169 PANTHER PTHR11049 4 150 2.9E-55 T 22-04-2016 MED134_RS09485 e15cf5378fc97be664e434bf8c50223b 169 Pfam PF03061 Thioesterase superfamily 26 99 5.2E-15 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS09485 e15cf5378fc97be664e434bf8c50223b 169 Gene3D G3DSA:3.10.129.10 4 155 2.1E-49 T 22-04-2016 IPR029069 HotDog domain MED134_RS09485 e15cf5378fc97be664e434bf8c50223b 169 SUPERFAMILY SSF54637 2 149 4.74E-42 T 22-04-2016 IPR029069 HotDog domain MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 PRINTS PR00147 DNA photolyase signature 338 356 2.9E-6 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 PRINTS PR00147 DNA photolyase signature 318 334 2.9E-6 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 Gene3D G3DSA:3.40.50.620 3 147 1.6E-33 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 318 330 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 PANTHER PTHR11455 8 494 3.2E-157 T 22-04-2016 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 SUPERFAMILY SSF52425 8 171 4.32E-37 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 Gene3D G3DSA:1.10.579.10 275 469 5.0E-51 T 22-04-2016 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 Gene3D G3DSA:1.25.40.80 195 274 1.5E-18 T 22-04-2016 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 SUPERFAMILY SSF48173 196 470 1.96E-81 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 Pfam PF00875 DNA photolyase 9 132 2.5E-21 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 PANTHER PTHR11455:SF21 8 494 3.2E-157 T 22-04-2016 MED134_RS10065 8ec3123eb51f648b4e06836e58e9cafd 494 Pfam PF03441 FAD binding domain of DNA photolyase 269 466 1.4E-52 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS02355 8d9502d4130f420702f7a79d3a97a892 248 Pfam PF08309 LVIVD repeat 176 203 0.0094 T 22-04-2016 IPR013211 LVIVD MED134_RS02355 8d9502d4130f420702f7a79d3a97a892 248 Pfam PF08309 LVIVD repeat 44 75 5.1E-4 T 22-04-2016 IPR013211 LVIVD MED134_RS02355 8d9502d4130f420702f7a79d3a97a892 248 SUPERFAMILY SSF63825 36 233 1.57E-7 T 22-04-2016 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 477 489 2.0E-22 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 498 514 2.0E-22 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 569 580 2.0E-22 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 459 471 2.0E-22 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 Pfam PF05649 Peptidase family M13 41 416 1.1E-88 T 22-04-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 Gene3D G3DSA:3.40.390.10 300 419 1.7E-106 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 Gene3D G3DSA:3.40.390.10 458 671 1.7E-106 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 SUPERFAMILY SSF55486 33 671 2.08E-188 T 22-04-2016 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 Pfam PF01431 Peptidase family M13 468 668 2.2E-72 T 22-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MED134_RS01575 edc1af7f88169c9eb9f6b8fdd7313dc4 671 PANTHER PTHR11733 39 671 1.8E-174 T 22-04-2016 IPR000718 Peptidase M13 GO:0004222|GO:0006508 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF14493 Helix-turn-helix domain 607 696 1.7E-21 T 22-04-2016 IPR029491 Helicase Helix-turn-helix domain MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 PANTHER PTHR13710:SF81 7 597 2.2E-260 T 22-04-2016 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SUPERFAMILY SSF46785 396 514 2.72E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Gene3D G3DSA:1.10.150.80 527 598 3.1E-24 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Gene3D G3DSA:3.40.50.300 6 202 3.0E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF00271 Helicase conserved C-terminal domain 222 328 1.2E-18 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 13 595 8.6E-221 T 22-04-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF00570 HRDC domain 527 592 5.3E-19 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SMART SM00487 21 215 1.7E-32 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SMART SM00341 522 602 4.5E-15 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SUPERFAMILY SSF52540 65 348 1.94E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Gene3D G3DSA:3.40.50.300 203 340 5.8E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF16124 RecQ zinc-binding 339 398 1.1E-14 T 22-04-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SUPERFAMILY SSF47819 526 598 1.61E-21 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF09382 RQC domain 402 512 2.9E-24 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SMART SM00956 405 508 8.4E-27 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 15 457 1.7E-164 T 22-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 PANTHER PTHR13710 7 597 2.2E-260 T 22-04-2016 MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Gene3D G3DSA:1.10.10.10 341 512 2.3E-44 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 SMART SM00490 247 328 4.1E-29 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS07870 bcabd354395436ca3890664f71d1b0ba 701 Pfam PF00270 DEAD/DEAH box helicase 27 185 6.0E-19 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 PANTHER PTHR10099 12 1218 0.0 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1216 18.767 T 22-04-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Gene3D G3DSA:3.30.1330.10 161 367 4.1E-31 T 22-04-2016 IPR016188 PurM-like, N-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Gene3D G3DSA:3.30.1330.10 591 749 5.2E-13 T 22-04-2016 IPR016188 PurM-like, N-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF55326 171 373 1.92E-42 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF52317 970 1215 6.33E-71 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF56042 760 950 3.29E-34 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Pfam PF02769 AIR synthase related protein, C-terminal domain 379 532 1.3E-19 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Pfam PF02769 AIR synthase related protein, C-terminal domain 777 903 2.9E-9 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF82697 11 103 4.24E-17 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 PANTHER PTHR10099:SF1 12 1218 0.0 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Gene3D G3DSA:3.40.50.880 973 1210 4.4E-8 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF56042 379 558 9.42E-38 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 971 1215 6.6E-79 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF55326 568 756 8.37E-53 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SMART SM01211 971 1215 3.8E-99 T 22-04-2016 MED134_RS01900 38e365f9083b689aa3bb1e2aff5e24c2 1219 SUPERFAMILY SSF109736 120 170 5.89E-11 T 22-04-2016 MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 410 475 2.0E-12 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 PANTHER PTHR38787 25 419 3.9E-100 T 22-04-2016 MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 Pfam PF08309 LVIVD repeat 109 126 0.91 T 22-04-2016 IPR013211 LVIVD MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 Pfam PF08309 LVIVD repeat 184 200 0.39 T 22-04-2016 IPR013211 LVIVD MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 Pfam PF08309 LVIVD repeat 73 99 0.061 T 22-04-2016 IPR013211 LVIVD MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 TIGRFAM TIGR04312 choice_anch_B: choice-of-anchor B domain 28 392 1.5E-170 T 22-04-2016 IPR027589 Choice-of-anchor B domain MED134_RS10945 d1d4a0a50df87c33f4439cd54464bcf2 475 SUPERFAMILY SSF50969 69 293 2.9E-5 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 PANTHER PTHR30128 504 632 1.7E-34 T 22-04-2016 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Gene3D G3DSA:2.120.10.30 164 417 4.7E-18 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Gene3D G3DSA:2.60.40.1120 431 514 2.9E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 SUPERFAMILY SSF49464 431 517 1.18E-6 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Gene3D G3DSA:1.25.40.10 27 131 1.9E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 SUPERFAMILY SSF82171 168 357 1.19E-16 T 22-04-2016 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Pfam PF13620 Carboxypeptidase regulatory-like domain 431 505 4.1E-8 T 22-04-2016 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Pfam PF00691 OmpA family 525 613 2.2E-19 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 PRINTS PR01021 OMPA domain signature 556 571 2.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 PRINTS PR01021 OMPA domain signature 571 587 2.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 PRINTS PR01021 OMPA domain signature 526 548 2.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Pfam PF07676 WD40-like Beta Propeller Repeat 326 362 0.0016 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Pfam PF07676 WD40-like Beta Propeller Repeat 214 234 0.0032 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Pfam PF07676 WD40-like Beta Propeller Repeat 275 310 1.6E-8 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 Gene3D G3DSA:3.30.1330.60 515 630 6.8E-34 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 SUPERFAMILY SSF103088 508 628 2.49E-30 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07695 e1f346f6235d561ab8814930f7a805e3 632 SUPERFAMILY SSF48452 28 135 4.05E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 SUPERFAMILY SSF53067 4 101 2.2E-25 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 Pfam PF00814 Glycoprotease family 36 169 2.3E-28 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 PANTHER PTHR11735:SF11 1 134 4.0E-41 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 SUPERFAMILY SSF53067 111 213 1.09E-14 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 PANTHER PTHR11735 1 134 4.0E-41 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 Gene3D G3DSA:3.30.420.40 3 120 2.7E-38 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 Gene3D G3DSA:3.30.420.40 121 191 1.6E-7 T 22-04-2016 MED134_RS11405 f069c1530c54e721f67469feb50e713e 225 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 215 6.2E-51 T 22-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 Gene3D G3DSA:3.30.420.10 81 207 1.9E-13 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 Pfam PF01693 Caulimovirus viroplasmin 6 48 3.8E-18 T 22-04-2016 IPR011320 Ribonuclease H1, N-terminal MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 PANTHER PTHR10642 1 152 6.5E-17 T 22-04-2016 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 PIRSF PIRSF037839 1 211 2.9E-89 T 22-04-2016 IPR017290 Ribonuclease H, bacteria GO:0004523 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 SUPERFAMILY SSF53098 79 207 8.85E-33 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 SUPERFAMILY SSF55658 6 49 1.62E-13 T 22-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 Pfam PF00075 RNase H 83 177 1.6E-6 T 22-04-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MED134_RS08965 2c37fa08c3c044f061dac4ac08fd011c 211 Gene3D G3DSA:3.40.970.10 4 52 2.9E-20 T 22-04-2016 IPR011320 Ribonuclease H1, N-terminal MED134_RS00240 ee96bc4bae6bb351a00b04c337b9c74e 292 Pfam PF01040 UbiA prenyltransferase family 11 262 1.2E-27 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 MED134_RS00240 ee96bc4bae6bb351a00b04c337b9c74e 292 PANTHER PTHR11048:SF27 21 282 5.5E-25 T 22-04-2016 MED134_RS00240 ee96bc4bae6bb351a00b04c337b9c74e 292 PANTHER PTHR11048 21 282 5.5E-25 T 22-04-2016 MED134_RS07330 abc212f1367b9bf9432a3db9933c46e5 1903 Pfam PF01345 Domain of unknown function DUF11 1004 1057 6.1E-10 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS07330 abc212f1367b9bf9432a3db9933c46e5 1903 Pfam PF01345 Domain of unknown function DUF11 880 931 4.5E-6 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS07330 abc212f1367b9bf9432a3db9933c46e5 1903 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 899 926 4.7E-6 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS07330 abc212f1367b9bf9432a3db9933c46e5 1903 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1020 1058 4.7E-11 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 484 3.4E-171 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 Pfam PF01546 Peptidase family M20/M25/M40 75 482 5.0E-18 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 Pfam PF07687 Peptidase dimerisation domain 202 290 1.1E-5 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014 332 487 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014 206 281 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014 1 187 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 103 121 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 82 101 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 365 383 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 161 179 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 253 272 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 208 225 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PRINTS PR00934 X-His dipeptidase (M25) signature 137 154 7.7E-66 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 Gene3D G3DSA:3.40.630.10 4 183 4.4E-96 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 Gene3D G3DSA:3.40.630.10 399 485 4.4E-96 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014:SF54 332 487 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014:SF54 206 281 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PANTHER PTHR11014:SF54 1 187 1.9E-143 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 PIRSF PIRSF016599 3 487 9.9E-189 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 SUPERFAMILY SSF53187 12 184 9.95E-58 T 22-04-2016 MED134_RS13560 ed2b534fae955ce9f4e130adef0a3203 487 SUPERFAMILY SSF53187 399 484 9.95E-58 T 22-04-2016 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 Pfam PF00072 Response regulator receiver domain 4 117 6.0E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 SUPERFAMILY SSF46894 141 207 2.45E-15 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 Gene3D G3DSA:1.10.10.10 141 207 3.9E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 SMART SM00448 2 117 6.2E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 4.7E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 Gene3D G3DSA:3.40.50.2300 1 140 4.1E-30 T 22-04-2016 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 PANTHER PTHR26402 2 207 6.3E-48 T 22-04-2016 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 PANTHER PTHR26402:SF458 2 207 6.3E-48 T 22-04-2016 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 SMART SM00421 144 201 9.8E-7 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS06885 e66eb99377994b46bf3f37c7ea9a9415 209 SUPERFAMILY SSF52172 1 130 2.13E-27 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 Pfam PF01597 Glycine cleavage H-protein 7 123 9.1E-42 T 22-04-2016 IPR002930 Glycine cleavage system H-protein MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 SUPERFAMILY SSF51230 2 125 4.32E-42 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 123 4.3E-45 T 22-04-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 Gene3D G3DSA:2.40.50.100 6 124 4.3E-47 T 22-04-2016 MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 27.851 T 22-04-2016 IPR002930 Glycine cleavage system H-protein MED134_RS11280 8a9e526f7a33387b8cbf47f81899d9b7 126 PANTHER PTHR11715 1 124 2.8E-58 T 22-04-2016 IPR002930 Glycine cleavage system H-protein MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 Gene3D G3DSA:3.60.21.10 33 301 1.9E-82 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 PANTHER PTHR11575 39 299 4.9E-71 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 Pfam PF00149 Calcineurin-like phosphoesterase 40 257 1.1E-15 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 SUPERFAMILY SSF56300 37 298 4.79E-78 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 PRINTS PR01607 Apyrase family signature 240 263 3.2E-16 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 PRINTS PR01607 Apyrase family signature 273 293 3.2E-16 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 PRINTS PR01607 Apyrase family signature 214 231 3.2E-16 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 PRINTS PR01607 Apyrase family signature 37 55 3.2E-16 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 MED134_RS05235 fd1ad6481d6f1314e0ca3468ce29c439 307 ProSitePatterns PS00785 5'-nucleotidase signature 1. 39 51 - T 22-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.7E-34 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 279 288 2.7E-34 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 456 470 2.7E-34 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 351 367 2.7E-34 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.7E-34 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 478 1.1E-193 T 22-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF01131 DNA topoisomerase 507 562 1.4E-9 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF01131 DNA topoisomerase 128 484 7.1E-106 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PANTHER PTHR11390 1 480 3.3E-274 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PANTHER PTHR11390 510 607 3.3E-274 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 SUPERFAMILY SSF56712 3 478 2.09E-179 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 SUPERFAMILY SSF56712 510 599 2.09E-179 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF01751 Toprim domain 5 113 2.7E-27 T 22-04-2016 IPR006171 Toprim domain MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:1.10.460.10 135 182 2.3E-54 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:1.10.460.10 510 575 2.3E-54 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:1.10.460.10 440 478 2.3E-54 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 SMART SM00437 237 524 5.6E-91 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 274 288 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PANTHER PTHR11390:SF27 1 480 3.3E-274 T 22-04-2016 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 PANTHER PTHR11390:SF27 510 607 3.3E-274 T 22-04-2016 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF13368 Topoisomerase C-terminal repeat 591 650 9.2E-13 T 22-04-2016 IPR025589 Topoisomerase C-terminal repeat MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF13368 Topoisomerase C-terminal repeat 654 701 4.7E-16 T 22-04-2016 IPR025589 Topoisomerase C-terminal repeat MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Pfam PF13368 Topoisomerase C-terminal repeat 712 757 4.9E-6 T 22-04-2016 IPR025589 Topoisomerase C-terminal repeat MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 SMART SM00436 104 192 1.2E-46 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 662 49.672 T 22-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 SMART SM00493 3 103 2.5E-26 T 22-04-2016 IPR006171 Toprim domain MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:2.70.20.10 308 439 3.2E-29 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:2.70.20.10 185 300 7.5E-24 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MED134_RS06110 70d9d6bb35bc829f34c94718ce014102 846 Gene3D G3DSA:3.40.50.140 1 134 2.3E-44 T 22-04-2016 IPR006171 Toprim domain MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 Gene3D G3DSA:3.40.1280.10 114 260 7.5E-41 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 PANTHER PTHR12029 5 260 9.6E-71 T 22-04-2016 MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 PANTHER PTHR12029:SF61 5 260 9.6E-71 T 22-04-2016 MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 Gene3D G3DSA:3.30.1330.30 9 104 5.2E-22 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 SUPERFAMILY SSF75217 103 260 2.94E-36 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 SUPERFAMILY SSF55315 3 101 3.06E-13 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like MED134_RS00130 8c7096499f29016ff04c7609349c083f 261 Pfam PF00588 SpoU rRNA Methylase family 116 253 1.6E-30 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 Pfam PF11028 Protein of unknown function (DUF2723) 37 215 2.1E-63 T 22-04-2016 IPR021280 Protein of unknown function DUF2723 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214:SF2 299 345 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214:SF2 5 230 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214:SF2 472 594 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214:SF2 610 736 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214:SF2 822 1065 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214 299 345 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214 5 230 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214 472 594 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214 610 736 9.8E-178 T 22-04-2016 MED134_RS11150 64abd2ee4f8c05fdf462cc12748f7578 1101 PANTHER PTHR16214 822 1065 9.8E-178 T 22-04-2016 MED134_RS06355 cf3986eac20ebb9ff1c852a5e4643892 1226 Pfam PF01433 Peptidase family M1 791 984 2.2E-7 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS06355 cf3986eac20ebb9ff1c852a5e4643892 1226 Gene3D G3DSA:1.10.390.10 961 1084 6.8E-12 T 22-04-2016 MED134_RS06355 cf3986eac20ebb9ff1c852a5e4643892 1226 SUPERFAMILY SSF55486 848 1082 9.77E-18 T 22-04-2016 MED134_RS03380 6c4996df76ae21c5eabf5304a06c529d 123 PANTHER PTHR28259 1 123 2.0E-37 T 22-04-2016 MED134_RS03380 6c4996df76ae21c5eabf5304a06c529d 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 121 19.071 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MED134_RS03380 6c4996df76ae21c5eabf5304a06c529d 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 116 2.0E-24 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MED134_RS03380 6c4996df76ae21c5eabf5304a06c529d 123 TIGRFAM TIGR00494 crcB: protein CrcB 5 119 1.6E-28 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 180 1.1E-34 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 PANTHER PTHR23407:SF1 1 186 3.1E-30 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 179 2.7E-24 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 PANTHER PTHR23407 1 186 3.1E-30 T 22-04-2016 MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 PIRSF PIRSF006806 1 183 2.2E-31 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 Gene3D G3DSA:3.40.50.10420 1 186 8.1E-35 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain MED134_RS08895 20dc8a29d5e2741631d462ac1335cffd 186 SUPERFAMILY SSF100950 2 186 2.79E-35 T 22-04-2016 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 2.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 179 338 1.7E-24 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 156 1.6E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 SUPERFAMILY SSF52540 138 434 9.74E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 433 4.0E-166 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Pfam PF01926 50S ribosome-binding GTPase 177 295 2.1E-24 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.9E-28 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 PIRSF PIRSF006485 1 435 3.3E-163 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Hamap MF_00195 GTPase Der [der]. 2 435 37.414 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Gene3D G3DSA:3.40.50.300 5 173 2.7E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Gene3D G3DSA:3.40.50.300 174 356 4.3E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 7.1E-28 T 22-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 SUPERFAMILY SSF52540 2 172 1.1E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 PANTHER PTHR11649 1 433 2.4E-128 T 22-04-2016 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 PANTHER PTHR11649:SF5 1 433 2.4E-128 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 MED134_RS07440 2cf906660c2bd9e9d0bc39a3a4877fe5 435 Gene3D G3DSA:3.30.300.20 357 435 1.3E-30 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 SUPERFAMILY SSF52540 140 376 5.28E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 Gene3D G3DSA:3.40.50.300 138 312 1.1E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 SMART SM00448 2 115 8.9E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 PANTHER PTHR32071 1 385 1.5E-170 T 22-04-2016 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 SUPERFAMILY SSF52172 1 185 2.13E-45 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 Gene3D G3DSA:3.40.50.2300 1 136 4.4E-40 T 22-04-2016 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 Pfam PF00158 Sigma-54 interaction domain 141 307 5.1E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 Pfam PF00072 Response regulator receiver domain 4 115 5.7E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 SMART SM00382 161 304 1.8E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13230 fa580f1e04cf5c08d43089563f95f311 387 Gene3D G3DSA:1.10.8.60 314 381 1.1E-21 T 22-04-2016 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 PANTHER PTHR21198:SF2 1 263 9.2E-81 T 22-04-2016 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 248 1.5E-61 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 SUPERFAMILY SSF53681 7 106 1.5E-33 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 Hamap MF_00258 Glutamate racemase [murI]. 5 255 33.327 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 215 3.1E-31 T 22-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 22-04-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 Gene3D G3DSA:3.40.50.1860 4 173 2.1E-51 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 PANTHER PTHR21198 1 263 9.2E-81 T 22-04-2016 MED134_RS07545 5fe29c76fe208e450a6bce26788b7f01 268 SUPERFAMILY SSF53681 110 251 7.36E-32 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS06025 0b46191cc07eb5e1212ce23ca5f62226 153 SUPERFAMILY SSF75217 13 146 6.15E-25 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS06025 0b46191cc07eb5e1212ce23ca5f62226 153 PANTHER PTHR12029 21 144 2.9E-18 T 22-04-2016 MED134_RS06025 0b46191cc07eb5e1212ce23ca5f62226 153 Pfam PF00588 SpoU rRNA Methylase family 17 144 2.9E-20 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS06025 0b46191cc07eb5e1212ce23ca5f62226 153 Gene3D G3DSA:3.40.1280.10 15 144 5.7E-25 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 Pfam PF03960 ArsC family 5 111 2.5E-12 T 22-04-2016 IPR006660 Arsenate reductase-like MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 Gene3D G3DSA:3.40.30.10 1 114 5.8E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 PANTHER PTHR30041:SF4 2 113 2.9E-30 T 22-04-2016 MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 2 113 4.9E-34 T 22-04-2016 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 SUPERFAMILY SSF52833 1 113 1.5E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02960 37e8c3624768170181e9b9b4b0b6fd2b 115 PANTHER PTHR30041 2 113 2.9E-30 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 12 68 1.5E-19 T 22-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Gene3D G3DSA:2.30.38.10 426 502 1.9E-6 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 ProSitePatterns PS00455 Putative AMP-binding domain signature. 247 258 - T 22-04-2016 IPR020845 AMP-binding, conserved site MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 PANTHER PTHR24095 8 630 0.0 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Gene3D G3DSA:3.40.50.980 253 410 1.8E-29 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 SUPERFAMILY SSF56801 2 629 5.36E-170 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Gene3D G3DSA:3.40.50.980 67 252 1.8E-41 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Pfam PF00501 AMP-binding enzyme 72 509 1.9E-89 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Pfam PF13193 AMP-binding enzyme C-terminal domain 519 598 2.5E-21 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 7 632 1.7E-288 T 22-04-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 Gene3D G3DSA:3.30.300.30 505 631 3.9E-22 T 22-04-2016 MED134_RS07855 cc738776fa3115927b21e18268b62cf0 636 PANTHER PTHR24095:SF116 8 630 0.0 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Gene3D G3DSA:2.40.10.170 3 78 1.8E-30 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 SMART SM00382 148 443 3.7E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 PANTHER PTHR15184:SF8 5 206 1.3E-304 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 PANTHER PTHR15184:SF8 228 502 1.3E-304 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 5 498 2.5E-233 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 SUPERFAMILY SSF52540 235 384 9.91E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 SUPERFAMILY SSF52540 81 207 9.91E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 371 380 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 PANTHER PTHR15184 5 206 1.3E-304 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 PANTHER PTHR15184 228 502 1.3E-304 T 22-04-2016 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Hamap MF_01347 ATP synthase subunit beta [atpB]. 3 498 55.706 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Gene3D G3DSA:1.10.1140.10 385 501 3.0E-49 T 22-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 SUPERFAMILY SSF47917 384 498 1.49E-48 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Gene3D G3DSA:3.40.50.300 81 382 1.1E-102 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 380 3.1E-60 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 SUPERFAMILY SSF50615 4 78 7.06E-22 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS07970 133fec44e6fc25e08bf783a884191067 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 77 1.5E-18 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 SUPERFAMILY SSF52540 335 582 1.6E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 Gene3D G3DSA:1.20.1560.10 14 327 2.2E-81 T 22-04-2016 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 PANTHER PTHR24221 12 587 2.2E-224 T 22-04-2016 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 Pfam PF00005 ABC transporter 361 510 3.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 Gene3D G3DSA:3.40.50.300 343 574 2.2E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 SUPERFAMILY SSF90123 15 326 3.4E-79 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 Pfam PF00664 ABC transporter transmembrane region 30 300 3.8E-53 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS03945 06826b047a3255e1c317f0aa0b33c26e 588 SMART SM00382 370 556 1.7E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 PANTHER PTHR11624:SF11 1 325 2.4E-158 T 22-04-2016 MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 Gene3D G3DSA:3.40.50.920 197 321 1.2E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 PANTHER PTHR11624 1 325 2.4E-158 T 22-04-2016 IPR033247 Transketolase family MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 SUPERFAMILY SSF52922 187 323 1.31E-42 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 SMART SM00861 4 179 6.0E-57 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.4E-45 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 SUPERFAMILY SSF52518 1 203 2.94E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 Gene3D G3DSA:3.40.50.970 2 195 4.0E-85 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS07200 ed226359b4f139595a44eeda0c512a04 325 Pfam PF02780 Transketolase, C-terminal domain 193 315 4.7E-42 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS03210 38286a0ae93202f5219f1a548f44e9b1 420 Pfam PF07075 Protein of unknown function (DUF1343) 69 419 2.6E-120 T 22-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 MED134_RS03210 38286a0ae93202f5219f1a548f44e9b1 420 PANTHER PTHR30480 12 419 2.0E-86 T 22-04-2016 MED134_RS03210 38286a0ae93202f5219f1a548f44e9b1 420 PANTHER PTHR30480:SF3 12 419 2.0E-86 T 22-04-2016 MED134_RS03210 38286a0ae93202f5219f1a548f44e9b1 420 PIRSF PIRSF016719 8 420 3.2E-93 T 22-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 Gene3D G3DSA:1.10.443.10 189 349 1.8E-30 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 PANTHER PTHR30349 7 353 7.9E-34 T 22-04-2016 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 Pfam PF00589 Phage integrase family 190 341 5.1E-20 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 SUPERFAMILY SSF56349 84 350 1.8E-46 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 PANTHER PTHR30349:SF22 7 353 7.9E-34 T 22-04-2016 MED134_RS08445 2e2d6544d37142549ba6501273bd5d54 357 Pfam PF13102 Phage integrase SAM-like domain 3 136 1.9E-18 T 22-04-2016 IPR025269 Phage integrase SAM-like domain MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 740 0.0 T 22-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 PANTHER PTHR36999 2 740 0.0 T 22-04-2016 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 SUPERFAMILY SSF53659 6 740 0.0 T 22-04-2016 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 PIRSF PIRSF009407 1 740 0.0 T 22-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 Gene3D G3DSA:3.40.718.10 341 364 2.6E-32 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 Gene3D G3DSA:3.40.718.10 540 647 2.6E-32 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 Gene3D G3DSA:3.40.718.10 159 289 2.6E-32 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS13925 b8a46eeabbe0ea74f1c5c088d657c10f 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 22-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 Pfam PF13715 CarboxypepD_reg-like domain 24 107 1.5E-11 T 22-04-2016 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 Gene3D G3DSA:2.170.130.10 135 240 8.7E-10 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 PANTHER PTHR32552 1 41 2.3E-23 T 22-04-2016 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 PANTHER PTHR32552 120 812 2.3E-23 T 22-04-2016 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 Gene3D G3DSA:2.40.170.20 241 811 7.0E-78 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS14195 6464db4a786401d5673718078979bbe5 812 SUPERFAMILY SSF49464 24 111 2.12E-12 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS14195 6464db4a786401d5673718078979bbe5 812 Gene3D G3DSA:2.60.40.1120 24 112 1.8E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS14195 6464db4a786401d5673718078979bbe5 812 SUPERFAMILY SSF56935 141 811 1.76E-81 T 22-04-2016 MED134_RS01105 d3953c19385ea599d0bc678bb0a46cb2 296 PANTHER PTHR17630 68 294 5.7E-55 T 22-04-2016 MED134_RS01105 d3953c19385ea599d0bc678bb0a46cb2 296 Pfam PF01738 Dienelactone hydrolase family 84 294 3.2E-48 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 MED134_RS01105 d3953c19385ea599d0bc678bb0a46cb2 296 SUPERFAMILY SSF53474 79 294 1.83E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01105 d3953c19385ea599d0bc678bb0a46cb2 296 Gene3D G3DSA:3.40.50.1820 73 293 1.7E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS01105 d3953c19385ea599d0bc678bb0a46cb2 296 PANTHER PTHR17630:SF32 68 294 5.7E-55 T 22-04-2016 MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 SUPERFAMILY SSF53335 43 222 8.74E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 Gene3D G3DSA:3.40.50.150 46 158 5.0E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 PANTHER PTHR23417 7 222 2.0E-43 T 22-04-2016 MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 36 216 1.7E-36 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 Pfam PF02390 Putative methyltransferase 46 217 4.5E-33 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 PANTHER PTHR23417:SF14 7 222 2.0E-43 T 22-04-2016 MED134_RS10775 a1b679ae002405b8659a761ff2020d91 224 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 8 224 23.439 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 PANTHER PTHR24220:SF117 51 249 3.0E-95 T 22-04-2016 MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 SMART SM00382 74 246 4.9E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 Gene3D G3DSA:3.40.50.300 60 256 2.8E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 PANTHER PTHR24220 51 249 3.0E-95 T 22-04-2016 MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 Pfam PF00005 ABC transporter 65 196 5.7E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13360 5f18fd1b1adcc2f843e13cadff54f77a 415 SUPERFAMILY SSF52540 59 251 7.17E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 Gene3D G3DSA:3.40.50.10740 1 157 1.0E-47 T 22-04-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 SUPERFAMILY SSF52317 1 157 5.04E-47 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 PANTHER PTHR30237 1 297 3.1E-83 T 22-04-2016 MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 Pfam PF02016 LD-carboxypeptidase 13 287 1.1E-74 T 22-04-2016 IPR003507 Peptidase family S66 MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 PANTHER PTHR30237:SF2 1 297 3.1E-83 T 22-04-2016 MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 Gene3D G3DSA:3.50.30.60 161 295 4.1E-37 T 22-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 SUPERFAMILY SSF141986 143 291 3.01E-37 T 22-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain MED134_RS08510 f22356627474b3a64940d5e3067a53a7 299 PIRSF PIRSF028757 1 299 6.9E-89 T 22-04-2016 IPR003507 Peptidase family S66 MED134_RS07255 ecad987292d377d8be6c750b396f267b 97 Gene3D G3DSA:2.60.40.10 13 83 7.8E-10 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS07255 ecad987292d377d8be6c750b396f267b 97 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 24 79 1.3E-10 T 22-04-2016 IPR032640 AMP-activated protein kinase, glycogen-binding domain MED134_RS07255 ecad987292d377d8be6c750b396f267b 97 SUPERFAMILY SSF81296 15 92 6.53E-18 T 22-04-2016 IPR014756 Immunoglobulin E-set MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Pfam PF07497 Rho termination factor, RNA-binding domain 211 283 3.6E-31 T 22-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Pfam PF07498 Rho termination factor, N-terminal domain 6 44 1.5E-9 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 315 519 1.9E-22 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SUPERFAMILY SSF52540 249 526 5.46E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Gene3D G3DSA:3.40.50.300 290 572 3.4E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Gene3D G3DSA:2.40.50.140 205 283 4.1E-48 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Gene3D G3DSA:2.40.50.140 3 46 4.1E-48 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SMART SM00382 326 511 9.4E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 PANTHER PTHR15184 139 574 1.9E-181 T 22-04-2016 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 Hamap MF_01884 Transcription termination factor Rho [rho]. 208 574 198.817 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 TIGRFAM TIGR00767 rho: transcription termination factor Rho 4 574 1.9E-192 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SUPERFAMILY SSF68912 3 46 1.1E-8 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SUPERFAMILY SSF50249 210 283 7.2E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SMART SM00959 6 48 4.5E-8 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 PANTHER PTHR15184:SF34 139 574 1.9E-181 T 22-04-2016 MED134_RS14470 74881a076a768a5adf7203c5d2ef63fe 574 SMART SM00357 211 277 2.5E-18 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 PRINTS PR01021 OMPA domain signature 259 281 8.4E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 PRINTS PR01021 OMPA domain signature 290 305 8.4E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 PRINTS PR01021 OMPA domain signature 305 321 8.4E-10 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 Pfam PF00691 OmpA family 260 348 5.8E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 SUPERFAMILY SSF103088 247 365 3.53E-26 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 Gene3D G3DSA:3.30.1330.60 256 367 1.9E-32 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14255 5c906ff7596f4a0bca3ca167131296f1 368 PANTHER PTHR30128 260 367 4.5E-24 T 22-04-2016 MED134_RS13480 352708ec74d6f59b55f057d58d543ded 464 Pfam PF13727 CoA-binding domain 65 210 2.0E-6 T 22-04-2016 MED134_RS13480 352708ec74d6f59b55f057d58d543ded 464 PANTHER PTHR30576 11 459 2.4E-84 T 22-04-2016 MED134_RS13480 352708ec74d6f59b55f057d58d543ded 464 Pfam PF02397 Bacterial sugar transferase 278 459 2.1E-51 T 22-04-2016 IPR003362 Bacterial sugar transferase MED134_RS13480 352708ec74d6f59b55f057d58d543ded 464 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 21 460 9.3E-104 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MED134_RS13480 352708ec74d6f59b55f057d58d543ded 464 PANTHER PTHR30576:SF0 11 459 2.4E-84 T 22-04-2016 MED134_RS05165 499b56407578247594c74917f5028dfd 236 Pfam PF00072 Response regulator receiver domain 8 117 4.4E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05165 499b56407578247594c74917f5028dfd 236 Gene3D G3DSA:1.10.10.10 135 232 9.1E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05165 499b56407578247594c74917f5028dfd 236 PANTHER PTHR26402:SF606 6 231 1.2E-78 T 22-04-2016 MED134_RS05165 499b56407578247594c74917f5028dfd 236 SUPERFAMILY SSF46894 137 232 9.07E-17 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS05165 499b56407578247594c74917f5028dfd 236 SMART SM00448 6 117 1.6E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05165 499b56407578247594c74917f5028dfd 236 Gene3D G3DSA:3.40.50.2300 2 125 6.0E-40 T 22-04-2016 MED134_RS05165 499b56407578247594c74917f5028dfd 236 SUPERFAMILY SSF52172 3 125 1.99E-38 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS05165 499b56407578247594c74917f5028dfd 236 SMART SM00862 156 230 1.1E-12 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS05165 499b56407578247594c74917f5028dfd 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 7.9E-16 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS05165 499b56407578247594c74917f5028dfd 236 PANTHER PTHR26402 6 231 1.2E-78 T 22-04-2016 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 PANTHER PTHR11236:SF3 325 375 1.4E-42 T 22-04-2016 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 PANTHER PTHR11236:SF3 101 303 1.4E-42 T 22-04-2016 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 Pfam PF00425 chorismate binding enzyme 101 367 7.6E-51 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 Gene3D G3DSA:3.60.120.10 83 375 7.3E-59 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 PANTHER PTHR11236 325 375 1.4E-42 T 22-04-2016 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 PANTHER PTHR11236 101 303 1.4E-42 T 22-04-2016 MED134_RS13755 50106f41de4e60c94a7d1bb1c6ea91d1 375 SUPERFAMILY SSF56322 33 375 1.57E-62 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 Gene3D G3DSA:1.20.1250.20 242 443 2.8E-25 T 22-04-2016 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 Gene3D G3DSA:1.20.1250.20 9 195 2.1E-25 T 22-04-2016 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PANTHER PTHR23500:SF22 4 442 1.5E-169 T 22-04-2016 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PRINTS PR00171 Sugar transporter signature 254 264 8.6E-21 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PRINTS PR00171 Sugar transporter signature 339 360 8.6E-21 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PRINTS PR00171 Sugar transporter signature 362 374 8.6E-21 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PRINTS PR00171 Sugar transporter signature 15 25 8.6E-21 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PRINTS PR00171 Sugar transporter signature 99 118 8.6E-21 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 PANTHER PTHR23500 4 442 1.5E-169 T 22-04-2016 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 SUPERFAMILY SSF103473 9 199 8.63E-68 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 SUPERFAMILY SSF103473 226 442 8.63E-68 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 Pfam PF00083 Sugar (and other) transporter 8 442 6.4E-105 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 298 315 - T 22-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MED134_RS10590 f367106b0485fd56ee5f5d39f10f8645 448 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 4 440 2.1E-105 T 22-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 Gene3D G3DSA:3.40.640.10 52 258 5.8E-24 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 PANTHER PTHR11601 2 357 1.2E-26 T 22-04-2016 MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 Gene3D G3DSA:3.90.1150.10 259 357 3.6E-8 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 PANTHER PTHR11601:SF31 2 357 1.2E-26 T 22-04-2016 MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 Pfam PF00266 Aminotransferase class-V 47 314 3.9E-8 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS07260 1ec1be8833e0f61465f9515778aa26f8 358 SUPERFAMILY SSF53383 14 357 2.32E-45 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS11550 0b1078733c9499a06a5ca618dbd22e2b 199 SUPERFAMILY SSF51161 2 166 1.52E-43 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS11550 0b1078733c9499a06a5ca618dbd22e2b 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 2.1E-9 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS11550 0b1078733c9499a06a5ca618dbd22e2b 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 4.1E-7 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS11550 0b1078733c9499a06a5ca618dbd22e2b 199 Gene3D G3DSA:2.160.10.10 10 167 1.2E-39 T 22-04-2016 MED134_RS11550 0b1078733c9499a06a5ca618dbd22e2b 199 PANTHER PTHR13061 1 178 2.9E-47 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Gene3D G3DSA:3.30.420.40 254 493 3.2E-90 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 SUPERFAMILY SSF51905 523 823 8.16E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 447 1.7E-53 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 SUPERFAMILY SSF53067 253 491 2.59E-73 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 877 887 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 530 547 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Gene3D G3DSA:3.30.420.40 1 250 3.1E-99 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 599 611 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 554 566 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 525 537 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 872 884 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 842 848 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 538 548 3.1E-30 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PANTHER PTHR10196:SF9 1 502 4.5E-224 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 492 1.7E-208 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Gene3D G3DSA:3.50.50.60 521 795 3.9E-40 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Hamap MF_00186 Glycerol kinase [glpK]. 3 494 53.661 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 360 380 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 933 1035 4.1E-17 T 22-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 PANTHER PTHR10196 1 502 4.5E-224 T 22-04-2016 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Pfam PF01266 FAD dependent oxidoreductase 526 856 4.4E-48 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 6.6E-79 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 MED134_RS11865 17f32faafbc8fe64038c1c33f9416b8c 1059 SUPERFAMILY SSF53067 4 251 1.3E-90 T 22-04-2016 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 PRINTS PR00124 ATP synthase C subunit signature 3 22 1.2E-9 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 PRINTS PR00124 ATP synthase C subunit signature 24 39 1.2E-9 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 PRINTS PR00124 ATP synthase C subunit signature 41 63 1.2E-9 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 63 10.553 T 22-04-2016 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 ProSitePatterns PS00605 ATP synthase c subunit signature. 31 52 - T 22-04-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 SUPERFAMILY SSF81333 6 62 2.62E-12 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 Pfam PF00137 ATP synthase subunit C 7 61 6.8E-8 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 61 3.1E-13 T 22-04-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MED134_RS09405 b7097f455598abd46d942e47befc05f6 63 Gene3D G3DSA:1.20.20.10 6 61 4.7E-17 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 SUPERFAMILY SSF52540 298 512 1.66E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Pfam PF12848 ABC transporter 219 294 1.2E-11 T 22-04-2016 IPR032781 ABC-transporter extension domain MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Gene3D G3DSA:3.40.50.300 5 277 4.0E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Gene3D G3DSA:3.40.50.300 313 551 8.7E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 PANTHER PTHR19211 559 597 1.9E-178 T 22-04-2016 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 PANTHER PTHR19211 4 521 1.9E-178 T 22-04-2016 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Pfam PF00005 ABC transporter 20 180 1.5E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Pfam PF00005 ABC transporter 329 463 4.4E-20 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 SMART SM00382 337 516 9.0E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 SMART SM00382 28 225 1.8E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 SUPERFAMILY SSF52540 4 230 5.0E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13335 a2c9eb988fe84c93f47713953e8a1c8f 639 Pfam PF16326 ABC transporter C-terminal domain 570 634 1.4E-11 T 22-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MED134_RS06445 51d3b9416cabd0a42d09db57eda07dab 157 PANTHER PTHR21666 28 157 8.5E-24 T 22-04-2016 MED134_RS06445 51d3b9416cabd0a42d09db57eda07dab 157 Gene3D G3DSA:3.90.1720.10 32 157 6.0E-35 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS06445 51d3b9416cabd0a42d09db57eda07dab 157 Pfam PF00877 NlpC/P60 family 45 155 6.8E-25 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS06445 51d3b9416cabd0a42d09db57eda07dab 157 SUPERFAMILY SSF54001 29 156 2.94E-34 T 22-04-2016 MED134_RS05980 4785a8466de5bf900bf9359a18b68546 506 PANTHER PTHR31901:SF5 1 408 2.5E-18 T 22-04-2016 MED134_RS05980 4785a8466de5bf900bf9359a18b68546 506 Pfam PF03321 GH3 auxin-responsive promoter 238 492 2.8E-43 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS05980 4785a8466de5bf900bf9359a18b68546 506 Pfam PF03321 GH3 auxin-responsive promoter 21 178 5.8E-21 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS05980 4785a8466de5bf900bf9359a18b68546 506 PANTHER PTHR31901 1 408 2.5E-18 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 PIRSF PIRSF000505 56 415 1.2E-93 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 SUPERFAMILY SSF55205 4 411 2.35E-82 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 ProSitePatterns PS00885 EPSP synthase signature 2. 323 341 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 412 24.231 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 58 406 6.4E-67 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 PANTHER PTHR21090 13 411 5.8E-91 T 22-04-2016 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 Gene3D G3DSA:3.65.10.10 11 58 5.5E-4 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 PANTHER PTHR21090:SF5 13 411 5.8E-91 T 22-04-2016 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 Gene3D G3DSA:3.65.10.10 213 411 4.4E-45 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS05560 fb6fb8d936520f96b857b017dded6954 417 Gene3D G3DSA:3.65.10.10 59 212 8.8E-40 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 MED134_RS09545 6589d26dbdf67e8618a39ca41eee0fc9 244 Pfam PF06439 Domain of Unknown Function (DUF1080) 42 242 5.0E-44 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 Pfam PF11734 TilS substrate C-terminal domain 360 428 4.4E-7 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 360 405 6.2E-7 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 SMART SM00977 360 432 4.7E-21 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 313 21.826 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 200 2.6E-54 T 22-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 Pfam PF01171 PP-loop family 20 196 1.9E-52 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 PANTHER PTHR11807:SF2 18 435 6.5E-72 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 Gene3D G3DSA:3.40.50.620 9 175 1.2E-18 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 SUPERFAMILY SSF52402 19 224 1.48E-52 T 22-04-2016 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 SUPERFAMILY SSF56037 344 430 5.75E-14 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MED134_RS04795 3ea8f3de299203ef3e403568712af740 435 PANTHER PTHR11807 18 435 6.5E-72 T 22-04-2016 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PANTHER PTHR11406 2 395 6.6E-207 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 Gene3D G3DSA:3.40.50.1270 179 383 4.4E-82 T 22-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 30 52 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 348 359 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 371 388 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PRINTS PR00477 Phosphoglycerate kinase family signature 135 157 3.0E-84 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 Gene3D G3DSA:3.40.50.1260 2 178 1.8E-69 T 22-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 PIRSF PIRSF000724 1 395 1.0E-149 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 395 39.576 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 SUPERFAMILY SSF53748 2 394 6.24E-147 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS09195 7fea4cc30b78f96fd175d26f271b3771 395 Pfam PF00162 Phosphoglycerate kinase 4 385 1.7E-152 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 Pfam PF02021 Uncharacterised protein family UPF0102 10 100 3.8E-23 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 SUPERFAMILY SSF52980 9 108 1.39E-22 T 22-04-2016 IPR011335 Restriction endonuclease type II-like MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 PANTHER PTHR34039 1 119 8.1E-25 T 22-04-2016 MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 PANTHER PTHR34039:SF1 1 119 8.1E-25 T 22-04-2016 MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 Gene3D G3DSA:3.40.1350.10 9 117 8.6E-29 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 MED134_RS08515 99f4e0252b5dff7a08e407125d5578db 119 Hamap MF_00048 UPF0102 protein YraN [yraN]. 3 113 19.052 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 363 79.135 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 22-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 361 6.8E-81 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 Gene3D G3DSA:3.40.50.300 1 171 1.9E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 Gene3D G3DSA:3.40.50.300 235 346 1.9E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 SUPERFAMILY SSF52540 1 346 3.47E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 PANTHER PTHR32182:SF0 1 363 3.9E-44 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 345 9.4E-15 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 ProSitePatterns PS00618 RecF protein signature 2. 303 321 - T 22-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MED134_RS05435 cba5aa603530253c49ed1922cb0c39ba 363 PANTHER PTHR32182 1 363 3.9E-44 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Pfam PF07715 TonB-dependent Receptor Plug Domain 113 236 5.9E-18 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Pfam PF13715 CarboxypepD_reg-like domain 26 104 6.8E-20 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF49464 24 96 4.84E-17 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532:SF51 509 589 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532:SF51 614 878 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532:SF51 203 482 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532:SF51 1 187 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532:SF51 900 1078 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.60.40.1120 26 106 1.4E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.170.130.10 107 237 1.2E-20 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532 509 589 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532 614 878 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532 203 482 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532 1 187 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 PANTHER PTHR11532 900 1078 5.2E-134 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Pfam PF00593 TonB dependent receptor 662 1063 2.3E-16 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.40.170.20 905 930 1.7E-43 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.40.170.20 978 1080 1.7E-43 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.40.170.20 468 840 1.7E-43 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.40.170.20 238 284 1.7E-43 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 Gene3D G3DSA:2.40.170.20 360 426 1.7E-43 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 25 1080 5.4E-160 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF56935 896 940 1.25E-75 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF56935 485 830 1.25E-75 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF56935 984 1080 1.25E-75 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF56935 351 441 1.25E-75 T 22-04-2016 MED134_RS12205 a901a0d13e91a41d2efa14c50559485e 1080 SUPERFAMILY SSF56935 100 265 1.25E-75 T 22-04-2016 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 Gene3D G3DSA:3.40.50.1820 421 662 5.2E-34 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 SUPERFAMILY SSF50993 6 413 1.94E-84 T 22-04-2016 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PANTHER PTHR11757:SF3 2 686 0.0 T 22-04-2016 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 Pfam PF00326 Prolyl oligopeptidase family 467 680 4.5E-66 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 7 408 1.2E-96 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 SUPERFAMILY SSF53474 420 662 4.28E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PANTHER PTHR11757 2 686 0.0 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 Gene3D G3DSA:2.130.10.120 75 411 5.8E-99 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 536 556 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 478 502 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 506 525 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 594 609 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 452 470 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS14265 523b8873fb07e08451ebac96ae894a61 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 612 634 1.6E-50 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MED134_RS01395 b51fbf1c45b7600957b241646667d989 170 SUPERFAMILY SSF51161 12 169 1.05E-39 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS01395 b51fbf1c45b7600957b241646667d989 170 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 124 152 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 MED134_RS01395 b51fbf1c45b7600957b241646667d989 170 PANTHER PTHR23416 25 170 2.5E-34 T 22-04-2016 MED134_RS01395 b51fbf1c45b7600957b241646667d989 170 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 116 150 5.9E-12 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS01395 b51fbf1c45b7600957b241646667d989 170 Gene3D G3DSA:2.160.10.10 23 169 3.2E-45 T 22-04-2016 MED134_RS04055 7787fe51fb0bdf386a2ff4ac761ff1f2 229 SUPERFAMILY SSF54593 7 116 1.36E-9 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS04055 7787fe51fb0bdf386a2ff4ac761ff1f2 229 Gene3D G3DSA:3.10.180.10 2 113 7.0E-14 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS00575 c28b1249c3866e22fa231ca12cca4c5a 161 Pfam PF10029 Predicted periplasmic protein (DUF2271) 28 154 3.8E-37 T 22-04-2016 IPR014469 Protein of unknown function DUF2271 MED134_RS05140 9a032f2a8cbc5ab24a0974a055eb8d53 406 PANTHER PTHR36454 1 406 1.5E-87 T 22-04-2016 MED134_RS05140 9a032f2a8cbc5ab24a0974a055eb8d53 406 PANTHER PTHR36454:SF1 1 406 1.5E-87 T 22-04-2016 MED134_RS05140 9a032f2a8cbc5ab24a0974a055eb8d53 406 Pfam PF06245 Protein of unknown function (DUF1015) 4 404 2.3E-102 T 22-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 MED134_RS05140 9a032f2a8cbc5ab24a0974a055eb8d53 406 PIRSF PIRSF033563 1 406 5.4E-89 T 22-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 MED134_RS14300 ac20e58d48c16307a9d67d0a9993edb2 413 Gene3D G3DSA:1.10.3210.10 4 129 5.5E-19 T 22-04-2016 IPR006674 HD domain MED134_RS14300 ac20e58d48c16307a9d67d0a9993edb2 413 SMART SM00471 24 140 4.0E-6 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS14300 ac20e58d48c16307a9d67d0a9993edb2 413 SUPERFAMILY SSF109604 6 197 1.22E-33 T 22-04-2016 MED134_RS14300 ac20e58d48c16307a9d67d0a9993edb2 413 Pfam PF01966 HD domain 29 128 4.2E-7 T 22-04-2016 IPR006674 HD domain MED134_RS13295 bd1b3dc502b448e29e1ace9c32d65cf4 227 Gene3D G3DSA:2.70.70.10 88 192 4.5E-21 T 22-04-2016 MED134_RS13295 bd1b3dc502b448e29e1ace9c32d65cf4 227 PANTHER PTHR21666 93 189 1.5E-12 T 22-04-2016 MED134_RS13295 bd1b3dc502b448e29e1ace9c32d65cf4 227 Pfam PF01551 Peptidase family M23 93 190 3.6E-18 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS13295 bd1b3dc502b448e29e1ace9c32d65cf4 227 SUPERFAMILY SSF51261 88 191 6.28E-21 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 22-04-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 137 3.0E-43 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 PANTHER PTHR21272 1 134 9.2E-71 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 2 136 6.0E-55 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 SUPERFAMILY SSF52304 1 136 1.96E-55 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 PIRSF PIRSF001399 1 140 4.6E-58 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 140 59.21 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 Pfam PF01220 Dehydroquinase class II 2 136 2.2E-54 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS04495 976d328d15ed488a1257e74bb57258be 140 Gene3D G3DSA:3.40.50.9100 1 137 1.3E-58 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 MED134_RS01075 cc099c47ccfb34099779216e987ccb7c 330 Pfam PF13557 Putative MetA-pathway of phenol degradation 30 283 6.2E-26 T 22-04-2016 IPR025737 MetA-pathway of phenol degradation, putative MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 143 156 - T 22-04-2016 IPR033135 ClpP, histidine active site MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 34 224 40.748 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PANTHER PTHR10381 32 223 1.7E-108 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 Gene3D G3DSA:3.90.226.10 47 222 1.9E-78 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 Pfam PF00574 Clp protease 47 223 3.3E-79 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 SUPERFAMILY SSF52096 43 222 8.7E-68 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PRINTS PR00127 Clp protease catalytic subunit P signature 50 65 3.5E-48 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PRINTS PR00127 Clp protease catalytic subunit P signature 142 161 3.5E-48 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PRINTS PR00127 Clp protease catalytic subunit P signature 121 138 3.5E-48 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PRINTS PR00127 Clp protease catalytic subunit P signature 90 110 3.5E-48 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PRINTS PR00127 Clp protease catalytic subunit P signature 199 218 3.5E-48 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS07475 4a4ce6dbd848f486bb1c83e35fac8c8b 224 PANTHER PTHR10381:SF22 32 223 1.7E-108 T 22-04-2016 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 PANTHER PTHR34069:SF2 1 335 2.6E-115 T 22-04-2016 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 335 2.6E-113 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 PANTHER PTHR34069 1 335 2.6E-115 T 22-04-2016 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 335 59.19 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 SUPERFAMILY SSF53901 4 335 7.06E-64 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Gene3D G3DSA:3.40.47.10 167 190 9.0E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Gene3D G3DSA:3.40.47.10 222 335 9.0E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 246 335 7.6E-36 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 190 2.2E-28 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS03920 b39cb4e1178e6b60b921ba6344f86436 335 Gene3D G3DSA:3.40.47.10 1 166 5.9E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 SUPERFAMILY SSF53067 149 338 1.56E-46 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 SUPERFAMILY SSF53067 10 147 2.2E-29 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 Gene3D G3DSA:3.90.640.10 186 259 3.4E-25 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 Gene3D G3DSA:3.30.420.40 264 318 1.3E-32 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 Gene3D G3DSA:3.30.420.40 159 185 1.3E-32 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 336 1.2E-121 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 2.6E-47 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 45 63 2.6E-47 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 301 327 2.6E-47 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 65 88 2.6E-47 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 2.6E-47 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PANTHER PTHR19375 6 328 6.2E-140 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 Pfam PF06723 MreB/Mbl protein 9 337 8.5E-125 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 PANTHER PTHR19375:SF117 6 328 6.2E-140 T 22-04-2016 MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 SMART SM00268 8 334 0.0024 T 22-04-2016 IPR004000 Actin family MED134_RS06230 21ba51c0e7dc6bcfd7599c5101ffc3f7 342 Gene3D G3DSA:3.30.420.40 10 158 1.3E-36 T 22-04-2016 MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 PANTHER PTHR30182 8 477 3.3E-197 T 22-04-2016 MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 Pfam PF03313 Serine dehydratase alpha chain 191 470 2.9E-98 T 22-04-2016 IPR005130 Serine dehydratase-like, alpha subunit MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 PANTHER PTHR30182:SF1 8 477 3.3E-197 T 22-04-2016 MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 SUPERFAMILY SSF143548 22 160 1.1E-42 T 22-04-2016 IPR029009 Allosteric substrate binding domain MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 8 473 4.1E-177 T 22-04-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 Gene3D G3DSA:3.30.1330.90 16 161 6.8E-49 T 22-04-2016 IPR029009 Allosteric substrate binding domain MED134_RS11840 88b9a067f144ef4c64678a5f83aec7e1 478 Pfam PF03315 Serine dehydratase beta chain 9 160 3.7E-52 T 22-04-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 PANTHER PTHR11699 1 480 1.9E-256 T 22-04-2016 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 Gene3D G3DSA:3.40.309.10 262 441 1.1E-65 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 PANTHER PTHR11699:SF213 1 480 1.9E-256 T 22-04-2016 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 Pfam PF00171 Aldehyde dehydrogenase family 15 475 1.9E-169 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 Gene3D G3DSA:3.40.605.10 2 261 2.9E-94 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MED134_RS12720 2b021093e2ae7a120f0b8fea2f4a5893 480 SUPERFAMILY SSF53720 2 479 2.09E-164 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 PANTHER PTHR11808 1 379 3.8E-196 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 Gene3D G3DSA:3.90.1150.10 244 379 3.8E-54 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 PANTHER PTHR11808:SF15 1 379 3.8E-196 T 22-04-2016 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 379 2.2E-155 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 Gene3D G3DSA:3.40.640.10 1 243 9.9E-97 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 PIRSF PIRSF001434 1 379 5.5E-148 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS09795 cf9734c288f32ced61042d5354482ed8 379 SUPERFAMILY SSF53383 3 379 4.98E-124 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS09260 47c5f676459bf58e7f2e6466d2767720 357 Gene3D G3DSA:3.40.50.2000 175 326 1.9E-10 T 22-04-2016 MED134_RS09260 47c5f676459bf58e7f2e6466d2767720 357 Pfam PF00534 Glycosyl transferases group 1 174 336 4.4E-16 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS09260 47c5f676459bf58e7f2e6466d2767720 357 SUPERFAMILY SSF53756 63 351 1.3E-30 T 22-04-2016 MED134_RS09260 47c5f676459bf58e7f2e6466d2767720 357 PANTHER PTHR12526 179 351 1.7E-16 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Gene3D G3DSA:1.10.10.350 403 501 5.7E-26 T 22-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Gene3D G3DSA:3.40.50.620 5 69 6.0E-50 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Gene3D G3DSA:3.40.50.620 203 252 6.0E-50 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.8E-26 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 211 2.8E-26 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PRINTS PR00987 Glutamyl-tRNA synthetase signature 217 225 2.8E-26 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.8E-26 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.8E-26 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 498 4.4E-144 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 501 31.156 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Gene3D G3DSA:1.10.1160.10 257 355 4.4E-31 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Gene3D G3DSA:3.90.800.10 70 202 1.2E-35 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 SUPERFAMILY SSF52374 5 338 2.44E-101 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451:SF41 283 351 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451:SF41 408 455 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451:SF41 3 252 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451 283 351 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451 408 455 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 PANTHER PTHR11451 3 252 2.9E-100 T 22-04-2016 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 346 1.6E-94 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09155 52639a8eb7c79009d6d2d72466981225 505 SUPERFAMILY SSF48163 340 501 2.35E-35 T 22-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MED134_RS09480 36d8e5e5cf29ff7fe60eaab09613b597 61 Pfam PF05532 CsbD-like 5 56 1.3E-17 T 22-04-2016 IPR008462 CsbD-like MED134_RS09480 36d8e5e5cf29ff7fe60eaab09613b597 61 SUPERFAMILY SSF69047 1 61 4.71E-18 T 22-04-2016 IPR008462 CsbD-like MED134_RS09480 36d8e5e5cf29ff7fe60eaab09613b597 61 Gene3D G3DSA:1.10.1470.10 1 61 8.1E-20 T 22-04-2016 IPR008462 CsbD-like MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 SUPERFAMILY SSF52540 294 520 5.48E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 SMART SM00533 12 316 0.005 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 Pfam PF00488 MutS domain V 338 520 1.1E-32 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 Gene3D G3DSA:3.40.50.300 295 520 2.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 PANTHER PTHR11361 11 606 1.6E-126 T 22-04-2016 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 SMART SM00534 335 520 4.2E-47 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 SUPERFAMILY SSF48334 127 290 2.35E-11 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 PANTHER PTHR11361:SF14 11 606 1.6E-126 T 22-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MED134_RS02710 5447315e412b72042d3789c554eab6c3 726 PIRSF PIRSF005814 1 726 1.7E-140 T 22-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Gene3D G3DSA:1.10.1040.10 211 309 7.0E-16 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 PANTHER PTHR23309:SF2 4 476 1.0E-112 T 22-04-2016 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 SUPERFAMILY SSF48179 364 459 4.51E-13 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 209 308 1.7E-11 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 SUPERFAMILY SSF51735 4 207 1.83E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01150 0484853d23c1fce52a466031c6394722 802 SUPERFAMILY SSF52096 486 799 3.89E-42 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Gene3D G3DSA:3.40.50.720 3 210 2.0E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01150 0484853d23c1fce52a466031c6394722 802 SUPERFAMILY SSF48179 207 321 1.19E-19 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Gene3D G3DSA:3.90.226.10 496 699 2.4E-24 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Gene3D G3DSA:1.10.1040.10 389 440 1.6E-7 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Pfam PF00378 Enoyl-CoA hydratase/isomerase 497 631 2.3E-12 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 206 2.1E-44 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS01150 0484853d23c1fce52a466031c6394722 802 PANTHER PTHR23309 4 476 1.0E-112 T 22-04-2016 MED134_RS11215 482b5460c887cecd90588dab53c61df7 454 PANTHER PTHR34856:SF4 97 453 2.0E-75 T 22-04-2016 MED134_RS11215 482b5460c887cecd90588dab53c61df7 454 PANTHER PTHR34856 97 453 2.0E-75 T 22-04-2016 MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 Pfam PF00271 Helicase conserved C-terminal domain 228 337 5.7E-24 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 Gene3D G3DSA:3.40.50.300 1 207 4.6E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 PANTHER PTHR24031 1 386 1.9E-141 T 22-04-2016 MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 SMART SM00487 20 218 2.7E-59 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 Pfam PF00270 DEAD/DEAH box helicase 25 191 2.7E-45 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 Gene3D G3DSA:3.40.50.300 208 368 5.6E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 SUPERFAMILY SSF52540 142 351 9.69E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 SUPERFAMILY SSF52540 1 205 3.29E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14135 9bb7f3a9cb51d71bb79e211d30ffa480 452 SMART SM00490 256 338 5.0E-26 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS14260 153cb984d6db4447828a403d45da1b88 107 PIRSF PIRSF004555 1 106 7.5E-17 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family MED134_RS14260 153cb984d6db4447828a403d45da1b88 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 93 14.486 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family MED134_RS14260 153cb984d6db4447828a403d45da1b88 107 SUPERFAMILY SSF82607 5 93 5.89E-13 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family MED134_RS14260 153cb984d6db4447828a403d45da1b88 107 Gene3D G3DSA:3.30.1310.10 1 104 7.1E-26 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family MED134_RS14260 153cb984d6db4447828a403d45da1b88 107 Pfam PF02575 YbaB/EbfC DNA-binding family 9 97 7.1E-16 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 PANTHER PTHR30055 1 164 2.7E-26 T 22-04-2016 MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 PANTHER PTHR30055:SF44 1 164 2.7E-26 T 22-04-2016 MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 SUPERFAMILY SSF46689 1 70 7.18E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 Gene3D G3DSA:1.10.357.10 4 184 1.1E-24 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.5E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS05720 877cf7275e75ca0f1d75ad6f9f5efc25 187 SUPERFAMILY SSF48498 80 172 3.3E-8 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 SUPERFAMILY SSF51395 466 1225 3.66E-257 T 22-04-2016 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Gene3D G3DSA:3.20.20.70 468 807 3.3E-93 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 PANTHER PTHR11938:SF1 6 1506 0.0 T 22-04-2016 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Gene3D G3DSA:3.60.20.10 17 459 3.8E-181 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Gene3D G3DSA:2.160.20.60 1243 1506 4.9E-100 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 SUPERFAMILY SSF56235 17 452 9.12E-143 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 PANTHER PTHR11938 6 1506 0.0 T 22-04-2016 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Pfam PF01645 Conserved region in glutamate synthase 822 1188 3.3E-154 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Pfam PF00310 Glutamine amidotransferases class-II 17 448 5.5E-175 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Pfam PF04898 Glutamate synthase central domain 476 759 1.7E-103 T 22-04-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Gene3D G3DSA:3.20.20.70 832 1227 1.7E-183 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 Pfam PF01493 GXGXG motif 1269 1456 4.6E-77 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MED134_RS13705 7820e51375cbe031c34bf9f23640cf9b 1512 SUPERFAMILY SSF69336 1238 1501 2.35E-92 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 225 400 8.8E-28 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PRINTS PR00981 Seryl-tRNA synthetase signature 278 291 3.4E-19 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PRINTS PR00981 Seryl-tRNA synthetase signature 353 369 3.4E-19 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PRINTS PR00981 Seryl-tRNA synthetase signature 318 331 3.4E-19 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PRINTS PR00981 Seryl-tRNA synthetase signature 335 351 3.4E-19 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PRINTS PR00981 Seryl-tRNA synthetase signature 266 278 3.4E-19 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 111 1.4E-22 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PANTHER PTHR11778 1 423 2.1E-160 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PANTHER PTHR11778:SF0 1 423 2.1E-160 T 22-04-2016 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 PIRSF PIRSF001529 1 422 2.8E-139 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 Gene3D G3DSA:1.10.287.40 1 108 1.2E-19 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 1.5E-131 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 SUPERFAMILY SSF46589 1 116 1.2E-23 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 Gene3D G3DSA:3.30.930.10 109 420 3.9E-114 T 22-04-2016 MED134_RS08280 24bb30db3b3a738cd38400d2ca7686ae 423 SUPERFAMILY SSF55681 121 422 1.13E-87 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.7E-6 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.7E-6 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 121 133 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 166 179 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00097 Anthranilate synthase component II signature 4 18 3.9E-30 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PANTHER PTHR11922 1 187 5.9E-72 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 SUPERFAMILY SSF52317 1 187 3.36E-50 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PANTHER PTHR11922:SF7 1 187 5.9E-72 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 Gene3D G3DSA:3.40.50.880 2 187 2.6E-56 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 5.7E-14 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 5.7E-14 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 5.7E-14 T 22-04-2016 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 187 1.6E-56 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13050 03e8b1a7061a841a67a2031209420d68 189 Pfam PF00117 Glutamine amidotransferase class-I 5 188 6.3E-47 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 13 295 16.132 T 22-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 16 294 4.7E-77 T 22-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 Pfam PF01040 UbiA prenyltransferase family 30 277 7.2E-56 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 PANTHER PTHR11048 14 297 1.3E-73 T 22-04-2016 MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 22-04-2016 IPR030470 UbiA prenyltransferase conserved site MED134_RS11320 1c75852761a2d03dcb5a40af12456b2f 297 PANTHER PTHR11048:SF3 14 297 1.3E-73 T 22-04-2016 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 PANTHER PTHR11122 1 165 3.4E-31 T 22-04-2016 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 PANTHER PTHR11122 195 256 3.4E-31 T 22-04-2016 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 Pfam PF01263 Aldose 1-epimerase 2 182 9.9E-20 T 22-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 SUPERFAMILY SSF74650 2 283 1.83E-44 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 PANTHER PTHR11122:SF14 1 165 3.4E-31 T 22-04-2016 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 PANTHER PTHR11122:SF14 195 256 3.4E-31 T 22-04-2016 MED134_RS13160 230da847b88d8aadb57818a9cf31655e 291 Gene3D G3DSA:2.70.98.10 4 256 1.4E-16 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 SMART SM01004 1 326 1.2E-203 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 4 324 4.1E-136 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PANTHER PTHR11458 2 326 3.1E-157 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 Gene3D G3DSA:3.20.20.70 3 326 4.9E-139 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 245 257 - T 22-04-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PIRSF PIRSF001415 1 327 8.1E-133 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 300 319 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 245 261 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 188 207 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 150 169 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 270 285 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 120 134 2.0E-54 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08710 287f817d929d20dc81b4d92196b64197 327 SUPERFAMILY SSF51569 2 326 3.08E-133 T 22-04-2016 MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 PANTHER PTHR21152:SF21 1 376 2.5E-135 T 22-04-2016 MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 Gene3D G3DSA:3.90.1150.10 262 372 1.8E-29 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 182 202 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 Pfam PF00266 Aminotransferase class-V 27 332 9.3E-29 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 PIRSF PIRSF000524 1 385 3.8E-100 T 22-04-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 SUPERFAMILY SSF53383 3 370 5.91E-97 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 Gene3D G3DSA:3.40.640.10 17 261 6.6E-57 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS05535 b5ed5d6b5014e6942c66b603c333dcde 387 PANTHER PTHR21152 1 376 2.5E-135 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SUPERFAMILY SSF109604 19 206 3.22E-67 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SMART SM00471 56 169 2.2E-6 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 PANTHER PTHR21262 8 736 1.3E-274 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Pfam PF04607 Region found in RelA / SpoT proteins 251 366 1.1E-24 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SUPERFAMILY SSF55021 660 735 1.37E-5 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Pfam PF02824 TGS domain 406 465 2.6E-20 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Gene3D G3DSA:3.30.70.260 665 727 3.4E-5 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SUPERFAMILY SSF81301 196 410 3.6E-48 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Gene3D G3DSA:3.10.20.30 405 468 1.0E-22 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Pfam PF13291 ACT domain 658 735 6.6E-16 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 41 734 7.7E-191 T 22-04-2016 IPR004811 RelA/SpoT family GO:0015969 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 PANTHER PTHR21262:SF0 8 736 1.3E-274 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SUPERFAMILY SSF81271 393 466 2.4E-20 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Gene3D G3DSA:3.30.460.10 194 345 5.5E-35 T 22-04-2016 MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 Pfam PF13328 HD domain 41 191 5.2E-45 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS03845 a92da3d753e7749352c2fe356e5e6335 736 SMART SM00954 251 366 1.9E-39 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 MED134_RS07130 74220607135d047d73f88faef1e321a1 291 TIGRFAM TIGR01200 GLPGLI: GLPGLI family protein 7 269 9.1E-51 T 22-04-2016 IPR005901 GLPGLI family protein MED134_RS07130 74220607135d047d73f88faef1e321a1 291 Pfam PF09697 Protein of unknown function (Porph_ging) 138 226 5.3E-26 T 22-04-2016 IPR005901 GLPGLI family protein MED134_RS11955 3411644f9e3255f33620f527839c900e 173 Gene3D G3DSA:3.40.50.150 10 147 1.3E-8 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS11955 3411644f9e3255f33620f527839c900e 173 SUPERFAMILY SSF53335 6 159 2.74E-8 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 23 112 3.6E-21 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 284 2.0E-85 T 22-04-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 Gene3D G3DSA:3.90.1170.20 6 134 1.6E-43 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 Gene3D G3DSA:3.20.20.70 135 275 2.3E-54 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 PIRSF PIRSF006250 5 286 1.8E-79 T 22-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 284 4.3E-52 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 SUPERFAMILY SSF54675 7 112 7.46E-26 T 22-04-2016 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 SUPERFAMILY SSF51690 114 284 8.63E-52 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 MED134_RS02250 f7f200f664a9fe235d7d09b1cadd3aff 286 PANTHER PTHR32179 9 284 1.1E-109 T 22-04-2016 MED134_RS08390 fa57bc32d2f3e2d9ea95ac251d5bbc7e 1610 PANTHER PTHR11219 855 1378 1.5E-38 T 22-04-2016 MED134_RS08390 fa57bc32d2f3e2d9ea95ac251d5bbc7e 1610 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1295 1378 3.5E-17 T 22-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 MED134_RS08390 fa57bc32d2f3e2d9ea95ac251d5bbc7e 1610 PANTHER PTHR11219:SF46 855 1378 1.5E-38 T 22-04-2016 MED134_RS01120 92f29e7f96c59d931e4ab4cb9d8f1a26 725 SUPERFAMILY SSF102114 325 549 7.06E-22 T 22-04-2016 MED134_RS01120 92f29e7f96c59d931e4ab4cb9d8f1a26 725 Gene3D G3DSA:3.80.30.20 353 530 3.6E-17 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS01120 92f29e7f96c59d931e4ab4cb9d8f1a26 725 SMART SM00729 348 560 2.5E-11 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.85E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.85E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PRINTS PR00315 GTP-binding elongation factor signature 64 72 1.85E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PRINTS PR00315 GTP-binding elongation factor signature 100 111 1.85E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PRINTS PR00315 GTP-binding elongation factor signature 84 94 1.85E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 Gene3D G3DSA:3.40.50.300 3 211 3.4E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 SUPERFAMILY SSF50465 311 412 2.21E-25 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 Gene3D G3DSA:2.40.30.10 312 412 6.5E-6 T 22-04-2016 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 Pfam PF00009 Elongation factor Tu GTP binding domain 3 209 1.6E-42 T 22-04-2016 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 Gene3D G3DSA:2.40.30.10 221 305 3.5E-12 T 22-04-2016 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 SUPERFAMILY SSF50447 220 306 1.21E-16 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 4 412 7.2E-150 T 22-04-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 SUPERFAMILY SSF52540 4 225 3.84E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14490 6fd4e00ca72433e5532474c8648adced 414 PANTHER PTHR23115 6 319 2.2E-55 T 22-04-2016 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PANTHER PTHR22594:SF4 1 508 1.5E-241 T 22-04-2016 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 Gene3D G3DSA:3.30.930.10 154 494 1.0E-113 T 22-04-2016 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 3 498 5.1E-183 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 SUPERFAMILY SSF50249 2 140 6.61E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 Gene3D G3DSA:2.40.50.140 4 140 8.0E-41 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 494 3.0E-79 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 9 497 42.001 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 SUPERFAMILY SSF55681 156 495 2.39E-110 T 22-04-2016 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 Pfam PF01336 OB-fold nucleic acid binding domain 49 132 4.2E-13 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PANTHER PTHR22594 1 508 1.5E-241 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 3.4E-37 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PRINTS PR00982 Lysyl-tRNA synthetase signature 378 394 3.4E-37 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 3.4E-37 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 3.4E-37 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS11650 e41d6ce9abd3ace5e751107019579b63 564 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 3.4E-37 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 2.7E-22 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 2.7E-22 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 2.7E-22 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 2.7E-22 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PANTHER PTHR11938:SF75 17 470 1.4E-151 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Gene3D G3DSA:3.50.50.60 234 405 5.6E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 130 3.4E-24 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 SUPERFAMILY SSF46548 2 153 1.83E-37 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 476 3.1E-211 T 22-04-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Gene3D G3DSA:1.10.1060.10 3 146 7.7E-40 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 458 5.5E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 SUPERFAMILY SSF51971 387 471 1.18E-7 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 PANTHER PTHR11938 17 470 1.4E-151 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 SUPERFAMILY SSF51971 142 405 4.24E-64 T 22-04-2016 MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Gene3D G3DSA:3.40.50.720 407 478 2.3E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS13710 d24eec4bf0d2f0cdb455ad04f66a0e20 487 Gene3D G3DSA:3.40.50.720 147 233 2.3E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 PANTHER PTHR13847:SF214 11 406 1.7E-148 T 22-04-2016 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 6 494 45.798 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 11 481 4.9E-190 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 PANTHER PTHR13847 11 406 1.7E-148 T 22-04-2016 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 SUPERFAMILY SSF51905 163 266 7.77E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 SUPERFAMILY SSF51905 309 335 7.77E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 SUPERFAMILY SSF51905 6 93 7.77E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 9 494 1.5E-211 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 Gene3D G3DSA:3.50.50.60 8 101 2.8E-16 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01760 bcb2e6752384620a75e3ebb0f3a32876 494 Gene3D G3DSA:3.50.50.60 151 332 2.8E-16 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS02625 25558f54c72f8edea9d8e9d95cfed582 147 Pfam PF07977 FabA-like domain 10 109 2.5E-14 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 MED134_RS02625 25558f54c72f8edea9d8e9d95cfed582 147 Gene3D G3DSA:3.10.129.10 1 140 4.2E-27 T 22-04-2016 IPR029069 HotDog domain MED134_RS02625 25558f54c72f8edea9d8e9d95cfed582 147 SUPERFAMILY SSF54637 5 144 7.03E-26 T 22-04-2016 IPR029069 HotDog domain MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Gene3D G3DSA:3.40.120.10 308 450 2.5E-32 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 SUPERFAMILY SSF55957 464 548 2.75E-12 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 487 545 5.5E-7 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 48 186 2.1E-42 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 144 153 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 PANTHER PTHR22573 23 572 7.8E-205 T 22-04-2016 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 440 1.3E-19 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Gene3D G3DSA:3.40.120.10 231 307 1.1E-19 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Gene3D G3DSA:3.30.310.50 476 547 9.9E-21 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 208 311 9.1E-24 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 SUPERFAMILY SSF53738 303 450 1.27E-26 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 SUPERFAMILY SSF53738 210 313 1.1E-18 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 SUPERFAMILY SSF53738 35 218 2.86E-47 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 PANTHER PTHR22573:SF54 23 572 7.8E-205 T 22-04-2016 MED134_RS03480 ec38ab8a68ca9217f0b8b3a1b4478e4c 575 Gene3D G3DSA:3.40.120.10 32 212 9.6E-60 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MED134_RS12660 88852ac0058a664736f128f3d8511da4 233 Pfam PF14224 Domain of unknown function (DUF4331) 24 95 6.3E-12 T 22-04-2016 IPR025566 Protein of unknown function DUF4331 MED134_RS12660 88852ac0058a664736f128f3d8511da4 233 Pfam PF14224 Domain of unknown function (DUF4331) 116 225 2.8E-15 T 22-04-2016 IPR025566 Protein of unknown function DUF4331 MED134_RS02240 44d54763b31338b3992f42400da64d71 187 SUPERFAMILY SSF54626 19 185 3.14E-14 T 22-04-2016 IPR016087 Chalcone isomerase GO:0016872 MED134_RS02240 44d54763b31338b3992f42400da64d71 187 Pfam PF16036 Chalcone isomerase-like 22 185 2.3E-56 T 22-04-2016 IPR016087 Chalcone isomerase GO:0016872 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 Pfam PF00912 Transglycosylase 72 248 2.3E-51 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 Pfam PF00905 Penicillin binding protein transpeptidase domain 438 694 1.6E-26 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 PANTHER PTHR32282 19 344 9.8E-167 T 22-04-2016 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 PANTHER PTHR32282 427 737 9.8E-167 T 22-04-2016 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 SUPERFAMILY SSF53955 61 276 9.56E-61 T 22-04-2016 IPR023346 Lysozyme-like domain MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 Gene3D G3DSA:1.10.3810.10 73 250 3.9E-58 T 22-04-2016 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 SUPERFAMILY SSF56601 282 347 4.63E-108 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 SUPERFAMILY SSF56601 234 252 4.63E-108 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 SUPERFAMILY SSF56601 428 758 4.63E-108 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 PANTHER PTHR32282:SF11 19 344 9.8E-167 T 22-04-2016 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 PANTHER PTHR32282:SF11 427 737 9.8E-167 T 22-04-2016 MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 Gene3D G3DSA:3.40.710.10 251 347 2.5E-117 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08780 a96e816989f218b708ff69afeb1aeb24 776 Gene3D G3DSA:3.40.710.10 426 759 2.5E-117 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 321 5.9E-52 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 SUPERFAMILY SSF51905 4 363 3.37E-48 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 Gene3D G3DSA:3.50.50.60 134 329 1.2E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 Gene3D G3DSA:3.50.50.60 4 133 2.4E-32 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PIRSF PIRSF000350 2 448 4.9E-68 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 4.0E-20 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.0E-20 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 4.0E-20 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 4.0E-20 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 4.0E-20 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PANTHER PTHR22912 4 449 1.6E-136 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 447 5.4E-23 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 Gene3D G3DSA:3.30.390.30 330 448 9.4E-29 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 256 270 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.1E-51 T 22-04-2016 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 SUPERFAMILY SSF55424 339 448 1.36E-29 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MED134_RS08560 e187a234326d35a248a0a9948a5c1ecb 449 PANTHER PTHR22912:SF157 4 449 1.6E-136 T 22-04-2016 MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 SUPERFAMILY SSF54211 10 118 5.06E-16 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 59 73 - T 22-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 8 119 1.2E-13 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 Pfam PF00825 Ribonuclease P 6 118 2.0E-21 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 Gene3D G3DSA:3.30.230.10 3 120 1.2E-25 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 5 121 13.914 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MED134_RS09060 3ae6788433c5805cda7471c7698b9b7a 126 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 34 111 4.0E-5 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PIRSF PIRSF000194 1 160 4.9E-60 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PANTHER PTHR22778 1 160 2.0E-48 T 22-04-2016 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 Gene3D G3DSA:3.40.430.10 1 160 1.1E-61 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 SUPERFAMILY SSF53597 1 160 5.44E-59 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PANTHER PTHR22778:SF16 1 160 2.0E-48 T 22-04-2016 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PRINTS PR00070 Dihydrofolate reductase signature 27 35 6.1E-16 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PRINTS PR00070 Dihydrofolate reductase signature 91 105 6.1E-16 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PRINTS PR00070 Dihydrofolate reductase signature 13 23 6.1E-16 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 PRINTS PR00070 Dihydrofolate reductase signature 40 51 6.1E-16 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 22-04-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS07270 1bdae7f6a4eeb3905152a46feed97d1a 160 Pfam PF00186 Dihydrofolate reductase 1 159 1.2E-61 T 22-04-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PANTHER PTHR11557:SF0 1 300 9.0E-104 T 22-04-2016 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 288 1.5E-82 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 Gene3D G3DSA:3.30.160.40 213 298 2.7E-21 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 22-04-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 SUPERFAMILY SSF53850 3 206 3.98E-58 T 22-04-2016 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 202 3.1E-64 T 22-04-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 SUPERFAMILY SSF54782 212 301 1.15E-22 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PRINTS PR00151 Porphobilinogen deaminase signature 73 92 1.2E-37 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PRINTS PR00151 Porphobilinogen deaminase signature 137 154 1.2E-37 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PRINTS PR00151 Porphobilinogen deaminase signature 118 135 1.2E-37 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 1.2E-37 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PRINTS PR00151 Porphobilinogen deaminase signature 42 62 1.2E-37 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PANTHER PTHR11557 1 300 9.0E-104 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 218 287 5.4E-14 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 Gene3D G3DSA:3.40.190.10 2 105 6.5E-39 T 22-04-2016 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 Gene3D G3DSA:3.40.190.10 106 191 5.9E-25 T 22-04-2016 MED134_RS08670 7317512b71259f0c110f1a4aa9ee7a4e 304 PIRSF PIRSF001438 1 304 1.4E-98 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:1.10.10.650 2 107 1.9E-34 T 22-04-2016 IPR023319 Tex-like protein, HTH domain MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:2.40.50.140 625 705 2.1E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SUPERFAMILY SSF50249 621 704 2.31E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Pfam PF16921 Tex protein YqgF-like domain 314 437 1.6E-48 T 22-04-2016 IPR032639 Tex protein, YqgF-like domain MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SMART SM00316 635 706 1.1E-16 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SUPERFAMILY SSF47781 456 543 2.45E-25 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:3.30.420.140 314 436 6.2E-49 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SUPERFAMILY SSF47781 546 617 5.78E-19 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 PANTHER PTHR10724:SF1 2 703 1.9E-282 T 22-04-2016 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Pfam PF00575 S1 RNA binding domain 634 704 5.2E-13 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SUPERFAMILY SSF53098 310 455 1.67E-46 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:1.10.3500.10 437 484 1.8E-87 T 22-04-2016 IPR023323 Tex-like domain MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:1.10.3500.10 108 310 1.8E-87 T 22-04-2016 IPR023323 Tex-like domain MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Pfam PF09371 Tex-like protein N-terminal domain 7 189 1.6E-59 T 22-04-2016 IPR018974 Tex-like protein, N-terminal MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 PANTHER PTHR10724 2 703 1.9E-282 T 22-04-2016 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Pfam PF12836 Helix-hairpin-helix motif 477 541 7.1E-25 T 22-04-2016 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 Gene3D G3DSA:1.10.150.310 485 616 3.1E-43 T 22-04-2016 IPR023097 Tex RuvX-like domain MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SMART SM00732 314 410 6.7E-28 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 MED134_RS08485 ed4d30b1804a660223afa7dccc260574 707 SUPERFAMILY SSF158832 2 307 2.09E-99 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Gene3D G3DSA:3.40.1160.10 1 49 6.9E-59 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Gene3D G3DSA:3.40.1160.10 107 295 6.9E-59 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 SUPERFAMILY SSF55021 382 468 6.87E-24 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 658 680 - T 22-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 PANTHER PTHR21499 3 468 1.4E-134 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 PANTHER PTHR21499:SF3 3 468 1.4E-134 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Pfam PF13840 ACT domain 390 454 2.6E-6 T 22-04-2016 IPR027795 GATS-like ACT domain MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 458 2.0E-118 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 SUPERFAMILY SSF51735 462 634 5.42E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 SUPERFAMILY SSF55021 302 378 2.33E-19 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Gene3D G3DSA:3.30.360.10 634 790 3.5E-51 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 SUPERFAMILY SSF53633 1 294 5.11E-74 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Pfam PF00742 Homoserine dehydrogenase 612 808 2.7E-51 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 PIRSF PIRSF000727 1 811 5.0E-275 T 22-04-2016 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00050|UniPathway: UPA00051|UniPathway: UPA00051 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 SUPERFAMILY SSF55347 612 795 4.51E-45 T 22-04-2016 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Gene3D G3DSA:3.40.50.720 462 633 1.1E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Pfam PF00696 Amino acid kinase family 2 281 4.4E-45 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS03025 0c2c539490b206040b7797fff907c7e7 811 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 470 601 3.7E-13 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MED134_RS03470 6cfbf1c64ee1d31600761dba26216938 313 PANTHER PTHR10859 2 306 5.9E-153 T 22-04-2016 MED134_RS03470 6cfbf1c64ee1d31600761dba26216938 313 PANTHER PTHR10859:SF100 2 306 5.9E-153 T 22-04-2016 MED134_RS03470 6cfbf1c64ee1d31600761dba26216938 313 Pfam PF00535 Glycosyl transferase family 2 4 165 2.7E-30 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS03470 6cfbf1c64ee1d31600761dba26216938 313 Gene3D G3DSA:3.90.550.10 1 174 3.8E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS03470 6cfbf1c64ee1d31600761dba26216938 313 SUPERFAMILY SSF53448 1 262 2.56E-46 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 Gene3D G3DSA:3.40.50.620 148 275 2.2E-17 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 Gene3D G3DSA:3.40.50.620 1 142 1.7E-35 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 PANTHER PTHR31964 2 146 3.1E-28 T 22-04-2016 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 SUPERFAMILY SSF52402 1 152 2.85E-34 T 22-04-2016 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 SUPERFAMILY SSF52402 152 275 1.93E-19 T 22-04-2016 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 PANTHER PTHR31964:SF26 2 146 3.1E-28 T 22-04-2016 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 Pfam PF00582 Universal stress protein family 2 142 1.0E-28 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 Pfam PF00582 Universal stress protein family 151 273 5.0E-12 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 PRINTS PR01438 Universal stress protein signature 1 18 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 PRINTS PR01438 Universal stress protein signature 102 114 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS11165 c5cefb749348643d0429d1cf28709565 276 PRINTS PR01438 Universal stress protein signature 120 142 3.2E-19 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS06015 8696059002cfec00c26db2a2eeb96ebe 179 Pfam PF00588 SpoU rRNA Methylase family 27 169 5.2E-30 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS06015 8696059002cfec00c26db2a2eeb96ebe 179 SUPERFAMILY SSF75217 13 175 7.19E-36 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS06015 8696059002cfec00c26db2a2eeb96ebe 179 PANTHER PTHR12029:SF60 18 176 1.1E-75 T 22-04-2016 MED134_RS06015 8696059002cfec00c26db2a2eeb96ebe 179 PANTHER PTHR12029 18 176 1.1E-75 T 22-04-2016 MED134_RS06015 8696059002cfec00c26db2a2eeb96ebe 179 Gene3D G3DSA:3.40.1280.10 15 176 8.0E-43 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS08085 f55f991f41e7abc0868cb9ce667b267c 229 PANTHER PTHR30231 8 213 1.4E-28 T 22-04-2016 MED134_RS08085 f55f991f41e7abc0868cb9ce667b267c 229 SUPERFAMILY SSF53098 41 217 9.83E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08085 f55f991f41e7abc0868cb9ce667b267c 229 Pfam PF00929 Exonuclease 47 208 6.4E-20 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS08085 f55f991f41e7abc0868cb9ce667b267c 229 SMART SM00479 45 218 1.3E-19 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS08085 f55f991f41e7abc0868cb9ce667b267c 229 Gene3D G3DSA:3.30.420.10 38 224 3.0E-39 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 SUPERFAMILY SSF52540 1 174 5.14E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 Gene3D G3DSA:3.40.50.300 1 192 5.3E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 PANTHER PTHR10695 1 173 4.1E-48 T 22-04-2016 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 189 23.015 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 Pfam PF01121 Dephospho-CoA kinase 2 173 2.5E-44 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 PRINTS PR00988 Uridine kinase signature 1 18 2.5E-7 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 PRINTS PR00988 Uridine kinase signature 133 143 2.5E-7 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS05175 a49a5afd34b068edb1d4dc0612f9bddd 199 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 186 8.0E-37 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 63 77 5.1E-5 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 209 229 5.1E-5 T 22-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 Gene3D G3DSA:3.40.192.10 14 141 6.2E-21 T 22-04-2016 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 SUPERFAMILY SSF51735 182 389 5.75E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 183 408 9.4E-31 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 SMART SM00839 181 410 7.1E-79 T 22-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 PANTHER PTHR11606 185 352 2.3E-24 T 22-04-2016 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 SUPERFAMILY SSF53223 11 118 1.63E-21 T 22-04-2016 MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 Gene3D G3DSA:3.40.50.720 184 400 6.1E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS06400 7b1a8209f9d38b52f30d29ec6e6b3341 410 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 26 115 3.4E-11 T 22-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 MED134_RS03105 cbb455c375163944474c9af572e879ec 267 Gene3D G3DSA:3.40.50.720 2 261 5.6E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.52E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.52E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.52E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.52E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.52E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 5.02E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 5.02E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 5.02E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PANTHER PTHR24322:SF513 142 173 1.9E-44 T 22-04-2016 MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PANTHER PTHR24322:SF513 7 126 1.9E-44 T 22-04-2016 MED134_RS03105 cbb455c375163944474c9af572e879ec 267 Pfam PF00106 short chain dehydrogenase 3 182 8.0E-46 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PANTHER PTHR24322 142 173 1.9E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 PANTHER PTHR24322 7 126 1.9E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS03105 cbb455c375163944474c9af572e879ec 267 SUPERFAMILY SSF51735 2 242 2.96E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 457 479 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 518 538 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 177 199 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 307 326 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 398 416 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PRINTS PR00175 Sodium/alanine symporter signature 279 297 2.1E-47 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PANTHER PTHR30330 143 561 2.7E-163 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PANTHER PTHR30330 35 94 2.7E-163 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PANTHER PTHR30330:SF3 143 561 2.7E-163 T 22-04-2016 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 PANTHER PTHR30330:SF3 35 94 2.7E-163 T 22-04-2016 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 TIGRFAM TIGR00835 agcS: amino acid carrier protein 138 549 2.7E-113 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04975 6c17d4da89ccd3d00c40b22f76a51bf5 561 Pfam PF01235 Sodium:alanine symporter family 141 557 4.0E-127 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 SUPERFAMILY SSF51395 1 340 5.5E-93 T 22-04-2016 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 Gene3D G3DSA:3.20.20.70 1 340 1.2E-121 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 PANTHER PTHR11938 6 340 1.5E-78 T 22-04-2016 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 Pfam PF01180 Dihydroorotate dehydrogenase 49 341 7.6E-92 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 PIRSF PIRSF000164 16 343 5.1E-98 T 22-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 340 43.94 T 22-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 5 341 8.7E-115 T 22-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS00950 9029d39290d54516809b1d37e9d63913 344 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 296 316 - T 22-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 MED134_RS13375 b79047cddf2ad6e5538cd170b0beda89 259 SUPERFAMILY SSF53448 2 197 1.76E-36 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13375 b79047cddf2ad6e5538cd170b0beda89 259 Pfam PF00535 Glycosyl transferase family 2 5 126 1.1E-18 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13375 b79047cddf2ad6e5538cd170b0beda89 259 Gene3D G3DSA:3.90.550.10 2 198 2.1E-31 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13375 b79047cddf2ad6e5538cd170b0beda89 259 PANTHER PTHR22916:SF4 2 221 1.2E-53 T 22-04-2016 MED134_RS13375 b79047cddf2ad6e5538cd170b0beda89 259 PANTHER PTHR22916 2 221 1.2E-53 T 22-04-2016 MED134_RS12575 af706ce8931bc6e68aec17ff83271182 186 PANTHER PTHR30574:SF1 6 76 1.8E-19 T 22-04-2016 MED134_RS12575 af706ce8931bc6e68aec17ff83271182 186 PANTHER PTHR30574:SF1 102 185 1.8E-19 T 22-04-2016 MED134_RS12575 af706ce8931bc6e68aec17ff83271182 186 Pfam PF04143 Sulphur transport 120 174 2.7E-14 T 22-04-2016 IPR007272 Sulphur transport domain MED134_RS12575 af706ce8931bc6e68aec17ff83271182 186 PANTHER PTHR30574 6 76 1.8E-19 T 22-04-2016 MED134_RS12575 af706ce8931bc6e68aec17ff83271182 186 PANTHER PTHR30574 102 185 1.8E-19 T 22-04-2016 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 Hamap MF_00487 Malate dehydrogenase [mdh]. 1 307 37.779 T 22-04-2016 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PIRSF PIRSF000102 1 307 4.3E-98 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PANTHER PTHR11540 1 302 6.0E-107 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 3.1E-33 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PRINTS PR00086 L-lactate dehydrogenase signature 27 51 3.1E-33 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 3.1E-33 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 3.1E-33 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PRINTS PR00086 L-lactate dehydrogenase signature 2 26 3.1E-33 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 Gene3D G3DSA:3.40.50.720 1 143 1.1E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 301 7.7E-22 T 22-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 Gene3D G3DSA:3.90.110.10 144 303 6.4E-48 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 PANTHER PTHR11540:SF16 1 302 6.0E-107 T 22-04-2016 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 SUPERFAMILY SSF51735 1 142 3.48E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 142 2.6E-42 T 22-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 1 303 2.0E-108 T 22-04-2016 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MED134_RS12780 9a38a48f679d9e247cb9c9defa70dced 308 SUPERFAMILY SSF56327 143 302 2.31E-43 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MED134_RS06165 abd8106f16ef4bb5bd4d2c70ef1ed366 255 Gene3D G3DSA:3.30.70.100 1 80 1.3E-14 T 22-04-2016 MED134_RS06165 abd8106f16ef4bb5bd4d2c70ef1ed366 255 SUPERFAMILY SSF55008 1 60 1.23E-12 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS06165 abd8106f16ef4bb5bd4d2c70ef1ed366 255 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MED134_RS06165 abd8106f16ef4bb5bd4d2c70ef1ed366 255 Pfam PF00403 Heavy-metal-associated domain 7 52 4.0E-8 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 SUPERFAMILY SSF103473 12 383 1.12E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 Pfam PF07690 Major Facilitator Superfamily 240 379 1.5E-8 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 Pfam PF07690 Major Facilitator Superfamily 30 235 6.5E-15 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 PANTHER PTHR23514 10 384 4.2E-72 T 22-04-2016 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 PANTHER PTHR23514:SF13 10 384 4.2E-72 T 22-04-2016 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 Gene3D G3DSA:1.20.1250.20 11 181 4.1E-15 T 22-04-2016 MED134_RS12755 3a9f23ef2007cac474c5a9ae88bac7dc 385 Gene3D G3DSA:1.20.1250.20 206 383 1.1E-12 T 22-04-2016 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 207 296 1.4E-12 T 22-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 29 153 1.2E-13 T 22-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 Gene3D G3DSA:1.10.800.10 16 160 3.2E-79 T 22-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 Gene3D G3DSA:1.10.800.10 205 337 3.2E-79 T 22-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 PANTHER PTHR11473 208 296 4.5E-39 T 22-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 PANTHER PTHR11473 29 162 4.5E-39 T 22-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 PANTHER PTHR11473:SF24 208 296 4.5E-39 T 22-04-2016 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 PANTHER PTHR11473:SF24 29 162 4.5E-39 T 22-04-2016 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 SUPERFAMILY SSF56534 207 329 7.19E-72 T 22-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MED134_RS11470 48b3a9d4d5f5f0e2a37a010950ad9db0 575 SUPERFAMILY SSF56534 17 161 7.19E-72 T 22-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 28 91 1.4E-10 T 22-04-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 PANTHER PTHR22572:SF117 101 274 4.3E-39 T 22-04-2016 MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 Gene3D G3DSA:2.160.10.10 189 297 8.8E-23 T 22-04-2016 MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 201 236 7.3E-8 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 124 158 4.2E-9 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 PANTHER PTHR22572 101 274 4.3E-39 T 22-04-2016 MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 SUPERFAMILY SSF51161 37 293 6.29E-62 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS02495 e4cc8834155783ac14d673c21aa236a8 311 Gene3D G3DSA:2.160.10.10 88 188 3.4E-24 T 22-04-2016 MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 PRINTS PR00069 Aldo-keto reductase signature 136 153 1.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 PRINTS PR00069 Aldo-keto reductase signature 215 239 1.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 PRINTS PR00069 Aldo-keto reductase signature 32 56 1.7E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 PANTHER PTHR11732 1 287 1.1E-94 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 SUPERFAMILY SSF51430 2 282 4.45E-69 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 Pfam PF00248 Aldo/keto reductase family 6 278 2.4E-53 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 Gene3D G3DSA:3.20.20.100 2 281 2.4E-67 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS09965 cafa6af519cf25d98f08f72369d9b23c 288 PANTHER PTHR11732:SF10 1 287 1.1E-94 T 22-04-2016 MED134_RS00780 14a8467888ea64a46f899596ba2e1f63 300 PANTHER PTHR30273:SF2 2 300 4.5E-43 T 22-04-2016 MED134_RS00780 14a8467888ea64a46f899596ba2e1f63 300 Pfam PF16344 Domain of unknown function (DUF4974) 212 294 2.0E-11 T 22-04-2016 IPR032508 Protein FecR, C-terminal MED134_RS00780 14a8467888ea64a46f899596ba2e1f63 300 Pfam PF04773 FecR protein 100 190 4.5E-20 T 22-04-2016 IPR006860 FecR protein MED134_RS00780 14a8467888ea64a46f899596ba2e1f63 300 PANTHER PTHR30273 2 300 4.5E-43 T 22-04-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MED134_RS00780 14a8467888ea64a46f899596ba2e1f63 300 PIRSF PIRSF018266 1 300 3.0E-50 T 22-04-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 129 139 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 SUPERFAMILY SSF53178 25 207 4.84E-57 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 Gene3D G3DSA:3.40.50.1470 20 208 4.3E-67 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 24 200 30.488 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 26 207 4.3E-56 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 37 50 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 PANTHER PTHR17224:SF1 10 207 6.3E-70 T 22-04-2016 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 Pfam PF01195 Peptidyl-tRNA hydrolase 26 205 1.4E-54 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS08295 f8650a2e686df992ee410d1633ce31b1 209 PANTHER PTHR17224 10 207 6.3E-70 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MED134_RS04810 c7a20d9fe63121055a5e5e3f516b6a26 142 Pfam PF08695 Cytochrome oxidase complex assembly protein 1 41 131 1.9E-5 T 22-04-2016 IPR014807 Cytochrome oxidase assembly protein 1 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 144 1.8E-27 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 Pfam PF00107 Zinc-binding dehydrogenase 186 306 2.3E-19 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 22-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 SUPERFAMILY SSF51735 149 312 4.55E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 Gene3D G3DSA:3.90.180.10 2 180 1.5E-62 T 22-04-2016 IPR011032 GroES-like MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 SMART SM00829 14 342 0.0031 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 SUPERFAMILY SSF50129 11 174 3.04E-50 T 22-04-2016 IPR011032 GroES-like MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 PANTHER PTHR11695 16 348 8.7E-162 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 PANTHER PTHR11695:SF608 16 348 8.7E-162 T 22-04-2016 MED134_RS01785 2122c868838d97238c8e4cd454cbef5a 348 Gene3D G3DSA:3.40.50.720 181 292 4.5E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12590 8663d1859d862b034c3bcd03f6812206 88 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MED134_RS12590 8663d1859d862b034c3bcd03f6812206 88 SUPERFAMILY SSF55008 1 66 2.36E-13 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS12590 8663d1859d862b034c3bcd03f6812206 88 Gene3D G3DSA:3.30.70.100 1 64 1.0E-13 T 22-04-2016 MED134_RS12590 8663d1859d862b034c3bcd03f6812206 88 Pfam PF00403 Heavy-metal-associated domain 5 63 5.9E-11 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS06620 1672d8a2a0402f1b2f0132c640164f53 365 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 55 193 1.5E-14 T 22-04-2016 IPR018550 Lipid A 3-O-deacylase-related MED134_RS06620 1672d8a2a0402f1b2f0132c640164f53 365 Gene3D G3DSA:2.40.160.20 46 194 5.5E-26 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS08030 25b55c80d347e6ff1e2caabe16a41923 326 SUPERFAMILY SSF103088 188 311 5.89E-30 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08030 25b55c80d347e6ff1e2caabe16a41923 326 PANTHER PTHR30128 185 318 2.2E-33 T 22-04-2016 MED134_RS08030 25b55c80d347e6ff1e2caabe16a41923 326 Pfam PF00691 OmpA family 204 305 9.8E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08030 25b55c80d347e6ff1e2caabe16a41923 326 Gene3D G3DSA:3.30.1330.60 189 313 1.1E-33 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08030 25b55c80d347e6ff1e2caabe16a41923 326 SUPERFAMILY SSF57997 21 179 6.54E-5 T 22-04-2016 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Pfam PF09334 tRNA synthetases class I (M) 9 401 3.0E-159 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 563 40.471 T 22-04-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Gene3D G3DSA:3.40.50.620 184 384 2.4E-91 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Gene3D G3DSA:3.40.50.620 6 145 2.4E-91 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 SUPERFAMILY SSF47323 394 606 4.3E-38 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 SUPERFAMILY SSF50249 587 685 5.39E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Gene3D G3DSA:1.10.730.10 385 552 1.2E-44 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Gene3D G3DSA:2.20.28.20 146 177 1.4E-18 T 22-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 553 2.5E-167 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PANTHER PTHR11946:SF72 1 649 0.0 T 22-04-2016 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 91 102 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 43 57 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 389 400 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 256 267 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 8.4E-28 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Pfam PF01588 Putative tRNA binding domain 599 686 4.7E-22 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 Gene3D G3DSA:2.40.50.140 586 693 5.1E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 SUPERFAMILY SSF57770 143 177 9.68E-12 T 22-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 567 686 1.4E-37 T 22-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 PANTHER PTHR11946 1 649 0.0 T 22-04-2016 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 SUPERFAMILY SSF52374 177 389 2.35E-97 T 22-04-2016 MED134_RS08495 a5ce165a1bacdf35f9d42e3b0812d570 695 SUPERFAMILY SSF52374 6 142 2.35E-97 T 22-04-2016 MED134_RS10345 df1ff75a1b59cadb1e84c0a843e0d676 482 SUPERFAMILY SSF74653 417 480 7.32E-8 T 22-04-2016 MED134_RS10345 df1ff75a1b59cadb1e84c0a843e0d676 482 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 421 479 2.2E-7 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 MED134_RS10345 df1ff75a1b59cadb1e84c0a843e0d676 482 Pfam PF05569 BlaR1 peptidase M56 144 253 1.3E-12 T 22-04-2016 IPR008756 Peptidase M56 MED134_RS04175 fc5fb48fc18afaa7278f65bfadd5eb76 108 PANTHER PTHR34299 1 108 7.5E-26 T 22-04-2016 MED134_RS04175 fc5fb48fc18afaa7278f65bfadd5eb76 108 Pfam PF01219 Prokaryotic diacylglycerol kinase 2 102 5.5E-33 T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 MED134_RS04175 fc5fb48fc18afaa7278f65bfadd5eb76 108 Gene3D G3DSA:1.10.3830.10 1 107 6.9E-34 T 22-04-2016 MED134_RS04175 fc5fb48fc18afaa7278f65bfadd5eb76 108 PANTHER PTHR34299:SF1 1 108 7.5E-26 T 22-04-2016 MED134_RS06330 4a8777695773959b4855045016d45d71 222 Gene3D G3DSA:1.10.357.10 26 198 8.7E-13 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS06330 4a8777695773959b4855045016d45d71 222 SUPERFAMILY SSF46689 18 95 3.75E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS06330 4a8777695773959b4855045016d45d71 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 4.6E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 SUPERFAMILY SSF144091 149 239 4.97E-18 T 22-04-2016 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 PANTHER PTHR22936 10 105 1.9E-31 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 PANTHER PTHR22936 150 235 1.9E-31 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 Pfam PF01694 Rhomboid family 44 238 1.0E-31 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 Gene3D G3DSA:1.20.1540.10 5 107 1.8E-42 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 Gene3D G3DSA:1.20.1540.10 153 238 1.8E-42 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS05410 4df0270bd3aaf7de9b3792b001056e57 244 SUPERFAMILY SSF144091 7 121 1.26E-24 T 22-04-2016 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 PANTHER PTHR11825:SF2 6 346 1.9E-108 T 22-04-2016 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 PIRSF PIRSF006468 2 348 1.1E-106 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 41 346 1.2E-94 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 ProSitePatterns PS00770 Aminotransferases class-IV signature. 227 256 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 Pfam PF01063 Amino-transferase class IV 67 307 4.2E-31 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 Gene3D G3DSA:3.20.10.10 172 333 3.4E-56 T 22-04-2016 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 PANTHER PTHR11825 6 346 1.9E-108 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 SUPERFAMILY SSF56752 7 343 5.62E-93 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS11565 5061b66607599e9bfd92eb8a399c939e 348 Gene3D G3DSA:3.30.470.10 2 171 5.5E-59 T 22-04-2016 MED134_RS12890 7170cd76af6321e99a2f3271f6398e90 309 Pfam PF02607 B12 binding domain 100 167 3.5E-5 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain MED134_RS12890 7170cd76af6321e99a2f3271f6398e90 309 Pfam PF13411 MerR HTH family regulatory protein 9 73 9.5E-14 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MED134_RS12890 7170cd76af6321e99a2f3271f6398e90 309 SUPERFAMILY SSF46955 9 81 2.47E-12 T 22-04-2016 IPR009061 Putative DNA-binding domain MED134_RS12890 7170cd76af6321e99a2f3271f6398e90 309 SMART SM00422 9 78 1.5E-8 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MED134_RS12890 7170cd76af6321e99a2f3271f6398e90 309 Gene3D G3DSA:1.10.1660.10 7 73 1.2E-12 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 437 510 6.28E-43 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 619 891 6.28E-43 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 PANTHER PTHR16026 31 312 3.5E-26 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 46 401 2.09E-69 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 437 499 2.09E-69 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 PANTHER PTHR16026 332 627 3.5E-26 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 981 1052 2.35E-9 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 SUPERFAMILY SSF69318 901 927 2.35E-9 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 PANTHER PTHR16026:SF0 332 627 3.5E-26 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Pfam PF07593 ASPIC and UnbV 524 591 5.6E-18 T 22-04-2016 IPR011519 ASPIC/UnbV MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 PANTHER PTHR16026:SF0 31 312 3.5E-26 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 64 127 2.9E-14 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 248 312 5.9E-13 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 823 883 2.7E-9 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 442 487 8.4E-7 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 766 888 7.0E-12 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 149 406 5.5E-33 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 982 1032 2.5E-4 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 644 765 3.3E-9 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 50 146 2.5E-10 T 22-04-2016 MED134_RS10645 d61880cd2c0d3a4e13d6485df6644701 1096 Gene3D G3DSA:2.130.10.130 442 500 5.5E-33 T 22-04-2016 MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 SUPERFAMILY SSF142433 255 413 3.79E-48 T 22-04-2016 IPR008136 CinA, C-terminal MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Pfam PF02464 Competence-damaged protein 260 411 2.5E-50 T 22-04-2016 IPR008136 CinA, C-terminal MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 266 409 1.5E-36 T 22-04-2016 IPR008136 CinA, C-terminal MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 PIRSF PIRSF006728 1 416 2.8E-125 T 22-04-2016 IPR008135 Competence-induced protein CinA MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Gene3D G3DSA:3.90.950.20 256 414 2.9E-52 T 22-04-2016 IPR008136 CinA, C-terminal MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 SUPERFAMILY SSF53218 1 191 5.1E-39 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 416 130.996 T 22-04-2016 IPR008135 Competence-induced protein CinA MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Gene3D G3DSA:3.40.980.10 1 81 8.7E-36 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Gene3D G3DSA:3.40.980.10 126 170 8.7E-36 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 PANTHER PTHR13939:SF0 1 415 3.8E-147 T 22-04-2016 MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 411 1.8E-94 T 22-04-2016 IPR008135 Competence-induced protein CinA MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 SMART SM00852 4 172 2.6E-33 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 167 2.9E-26 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 Pfam PF00994 Probable molybdopterin binding domain 4 170 1.0E-34 T 22-04-2016 IPR001453 MoaB/Mog domain MED134_RS05080 39722df90c69cd258b9a6c3e7aecd6bc 416 PANTHER PTHR13939 1 415 3.8E-147 T 22-04-2016 MED134_RS14335 d1fd1b2a41dfb0834fa59614644e417c 105 PANTHER PTHR34068 1 105 7.4E-12 T 22-04-2016 MED134_RS14335 d1fd1b2a41dfb0834fa59614644e417c 105 PANTHER PTHR34068:SF1 1 105 7.4E-12 T 22-04-2016 MED134_RS14335 d1fd1b2a41dfb0834fa59614644e417c 105 Pfam PF01906 Putative heavy-metal-binding 1 103 2.8E-18 T 22-04-2016 IPR002765 Uncharacterised protein family UPF0145 MED134_RS14335 d1fd1b2a41dfb0834fa59614644e417c 105 Gene3D G3DSA:3.30.110.70 1 103 1.8E-21 T 22-04-2016 IPR002765 Uncharacterised protein family UPF0145 MED134_RS14335 d1fd1b2a41dfb0834fa59614644e417c 105 SUPERFAMILY SSF117782 1 104 4.84E-21 T 22-04-2016 IPR002765 Uncharacterised protein family UPF0145 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82714 903 988 5.62E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82693 166 202 5.75E-13 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063 821 1104 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063 2 534 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063 1130 1247 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063 615 756 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82866 310 529 7.85E-31 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063:SF19 821 1104 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063:SF19 2 534 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063:SF19 1130 1247 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PANTHER PTHR32063:SF19 615 756 0.0 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:3.30.70.1320 290 319 8.5E-7 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:3.30.70.1320 168 199 8.5E-7 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82693 288 334 5.75E-13 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82866 986 1243 1.7E-36 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:1.10.3850.10 996 1239 6.1E-48 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:1.20.1640.10 320 537 9.8E-49 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PRINTS PR00702 Acriflavin resistance protein family signature 414 438 1.2E-9 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PRINTS PR00702 Acriflavin resistance protein family signature 51 69 1.2E-9 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PRINTS PR00702 Acriflavin resistance protein family signature 359 382 1.2E-9 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 PRINTS PR00702 Acriflavin resistance protein family signature 386 407 1.2E-9 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:3.30.2090.10 204 286 2.9E-18 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:3.30.2090.10 903 989 3.7E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Pfam PF00873 AcrB/AcrD/AcrF family 38 537 4.9E-101 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Pfam PF00873 AcrB/AcrD/AcrF family 829 1108 2.8E-45 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Pfam PF00873 AcrB/AcrD/AcrF family 1126 1238 1.3E-24 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Pfam PF00873 AcrB/AcrD/AcrF family 631 754 3.8E-11 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82693 57 139 7.32E-17 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 Gene3D G3DSA:3.30.70.1430 58 154 2.9E-21 T 22-04-2016 MED134_RS00750 61d3bc004003e3a2b9c7c276c6726c11 1250 SUPERFAMILY SSF82714 204 285 4.45E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS06670 da9f78fcd9da37cf2e4c0381e3750033 157 SUPERFAMILY SSF109854 9 150 9.34E-19 T 22-04-2016 MED134_RS06670 da9f78fcd9da37cf2e4c0381e3750033 157 Gene3D G3DSA:1.20.120.450 15 150 7.8E-7 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 135 792 1.0E-77 T 22-04-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Gene3D G3DSA:2.60.40.1120 23 110 4.0E-12 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Gene3D G3DSA:2.170.130.10 122 241 6.0E-25 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 PANTHER PTHR32552:SF10 103 792 1.5E-100 T 22-04-2016 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 PANTHER PTHR32552 103 792 1.5E-100 T 22-04-2016 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 SUPERFAMILY SSF49464 23 114 4.9E-14 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Pfam PF13715 CarboxypepD_reg-like domain 24 109 2.4E-17 T 22-04-2016 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 SUPERFAMILY SSF56935 102 792 5.8E-107 T 22-04-2016 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Pfam PF00593 TonB dependent receptor 540 790 1.2E-19 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Gene3D G3DSA:2.40.170.20 249 792 1.8E-107 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13170 fd863b07903b25224b69fd758f6dfa48 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 133 224 2.7E-12 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 PANTHER PTHR11532:SF57 1 114 1.7E-21 T 22-04-2016 MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 SMART SM00327 274 461 3.7E-10 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 PANTHER PTHR11532 1 114 1.7E-21 T 22-04-2016 MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 SUPERFAMILY SSF53300 275 451 4.15E-19 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 SUPERFAMILY SSF49464 21 91 1.57E-12 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 Gene3D G3DSA:2.60.40.1120 23 105 1.4E-6 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 Gene3D G3DSA:3.40.50.410 273 460 6.1E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 Pfam PF00092 von Willebrand factor type A domain 276 444 1.4E-10 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS14680 087a1ee4ace34c9529d48405e9df32eb 483 Pfam PF13715 CarboxypepD_reg-like domain 23 101 3.0E-14 T 22-04-2016 MED134_RS07190 40622705703331d454d399831f995e6c 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 7 163 33.583 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS07190 40622705703331d454d399831f995e6c 175 SUPERFAMILY SSF50324 8 164 3.92E-64 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS07190 40622705703331d454d399831f995e6c 175 Pfam PF00719 Inorganic pyrophosphatase 11 162 6.0E-58 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS07190 40622705703331d454d399831f995e6c 175 PANTHER PTHR10286 9 164 2.4E-65 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS07190 40622705703331d454d399831f995e6c 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 58 64 - T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS07190 40622705703331d454d399831f995e6c 175 Gene3D G3DSA:3.90.80.10 4 164 5.9E-59 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 MED134_RS02305 cf102fe9cb2041bf53b9d909ca1bfa70 271 PANTHER PTHR39200:SF1 17 271 2.1E-14 T 22-04-2016 MED134_RS02305 cf102fe9cb2041bf53b9d909ca1bfa70 271 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 59 254 4.9E-32 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS02305 cf102fe9cb2041bf53b9d909ca1bfa70 271 PANTHER PTHR39200 17 271 2.1E-14 T 22-04-2016 MED134_RS11950 17a78808237101feac7300a1bb0c3ba6 283 Gene3D G3DSA:3.90.550.10 3 164 1.1E-23 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11950 17a78808237101feac7300a1bb0c3ba6 283 PANTHER PTHR22916 1 164 5.0E-20 T 22-04-2016 MED134_RS11950 17a78808237101feac7300a1bb0c3ba6 283 SUPERFAMILY SSF53448 2 251 7.88E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11950 17a78808237101feac7300a1bb0c3ba6 283 Pfam PF00535 Glycosyl transferase family 2 5 142 3.1E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 471 487 9.7E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 9.7E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 515 529 9.7E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 9.7E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 SUPERFAMILY SSF50249 1 110 1.16E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PANTHER PTHR22594 366 568 5.7E-229 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PANTHER PTHR22594 1 299 5.7E-229 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PANTHER PTHR22594:SF5 366 568 5.7E-229 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 PANTHER PTHR22594:SF5 1 299 5.7E-229 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Gene3D G3DSA:3.30.930.10 137 278 2.0E-105 T 22-04-2016 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Gene3D G3DSA:3.30.930.10 410 581 2.0E-105 T 22-04-2016 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 579 1.2E-211 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 554 1.2E-102 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Gene3D G3DSA:2.40.50.140 1 108 2.0E-34 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Pfam PF01336 OB-fold nucleic acid binding domain 19 103 9.7E-12 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Pfam PF02938 GAD domain 311 400 4.1E-11 T 22-04-2016 IPR029351 GAD domain MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 SUPERFAMILY SSF55261 291 415 1.07E-29 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 SUPERFAMILY SSF55681 421 580 1.91E-95 T 22-04-2016 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 SUPERFAMILY SSF55681 115 294 1.91E-95 T 22-04-2016 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 560 33.549 T 22-04-2016 MED134_RS10700 651c6530c04d921ceafa8aa74e95e58c 582 Gene3D G3DSA:3.30.1360.30 279 409 1.7E-37 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 MED134_RS08910 ed870055978bc3f6eaeeff6031c1aebe 148 Gene3D G3DSA:2.40.70.10 3 129 1.6E-32 T 22-04-2016 IPR021109 Aspartic peptidase domain MED134_RS08910 ed870055978bc3f6eaeeff6031c1aebe 148 SUPERFAMILY SSF50630 5 132 4.5E-32 T 22-04-2016 IPR021109 Aspartic peptidase domain MED134_RS08910 ed870055978bc3f6eaeeff6031c1aebe 148 PANTHER PTHR38037 2 148 4.3E-19 T 22-04-2016 MED134_RS08910 ed870055978bc3f6eaeeff6031c1aebe 148 Pfam PF05618 Putative ATP-dependant zinc protease 5 134 7.2E-17 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 SUPERFAMILY SSF53098 2 210 1.77E-59 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 SUPERFAMILY SSF53098 359 505 1.77E-59 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Pfam PF14579 Helix-hairpin-helix motif 1101 1190 6.2E-25 T 22-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 SMART SM00481 263 351 1.3E-16 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Gene3D G3DSA:1.10.150.280 1118 1172 1.3E-6 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 PANTHER PTHR32294:SF0 333 1463 0.0 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 PANTHER PTHR32294:SF0 258 311 0.0 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Gene3D G3DSA:3.20.20.140 261 542 3.6E-31 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Pfam PF02811 PHP domain 264 453 1.2E-40 T 22-04-2016 IPR004013 PHP domain GO:0003824 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 SMART SM00479 1 192 7.3E-15 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 590 1027 2.8E-165 T 22-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 PANTHER PTHR32294 333 1463 0.0 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 PANTHER PTHR32294 258 311 0.0 T 22-04-2016 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 262 1332 0.0 T 22-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Pfam PF00929 Exonuclease 3 182 2.5E-10 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS07610 848bf3dbc28be0056d56dfbfe273a35d 1463 Gene3D G3DSA:3.30.420.10 1 189 4.5E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 SUPERFAMILY SSF52540 417 472 1.36E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 SUPERFAMILY SSF52540 41 380 1.36E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 Pfam PF13538 UvrD-like helicase C-terminal domain 418 467 1.6E-19 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 Gene3D G3DSA:3.40.50.300 19 222 1.2E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 Pfam PF13604 AAA domain 38 226 7.6E-24 T 22-04-2016 MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 Gene3D G3DSA:3.40.50.300 251 293 6.9E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01305 d8bc349b111aff11e959be767b0c42ed 478 Gene3D G3DSA:3.40.50.300 410 470 6.9E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12000 6c3cdc9cd41da39fe2c0526fa0980438 406 SUPERFAMILY SSF53756 9 365 1.44E-15 T 22-04-2016 MED134_RS12000 6c3cdc9cd41da39fe2c0526fa0980438 406 Pfam PF13692 Glycosyl transferases group 1 195 332 4.7E-17 T 22-04-2016 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PANTHER PTHR24423 343 724 2.3E-117 T 22-04-2016 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 428 4.5E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PANTHER PTHR24423:SF382 343 724 2.3E-117 T 22-04-2016 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 591 7.3E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SUPERFAMILY SSF52172 619 738 1.39E-34 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 2.0E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Pfam PF13181 Tetratricopeptide repeat 73 104 0.0096 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Gene3D G3DSA:3.40.50.2300 618 737 2.7E-38 T 22-04-2016 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SUPERFAMILY SSF55874 418 590 1.19E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Pfam PF00072 Response regulator receiver domain 622 725 1.3E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SMART SM00388 364 429 8.7E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SMART SM00387 476 592 1.2E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SMART SM00448 620 731 2.8E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Gene3D G3DSA:1.10.287.130 357 425 2.0E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Gene3D G3DSA:3.30.565.10 431 595 2.0E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SUPERFAMILY SSF47384 350 429 1.45E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 Gene3D G3DSA:1.25.40.10 42 269 9.0E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08725 b6fa16075e7817f4cf644c7a1a9c6fbd 743 SUPERFAMILY SSF48452 44 186 1.73E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Pfam PF02803 Thiolase, C-terminal domain 276 399 5.7E-45 T 22-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Pfam PF00108 Thiolase, N-terminal domain 4 268 1.6E-78 T 22-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 PANTHER PTHR18919:SF91 1 402 1.6E-210 T 22-04-2016 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 SUPERFAMILY SSF53901 277 400 3.68E-45 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Gene3D G3DSA:3.40.47.10 283 400 8.5E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Gene3D G3DSA:3.40.47.10 150 198 8.5E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 SUPERFAMILY SSF53901 2 276 2.45E-77 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 PANTHER PTHR18919 1 402 1.6E-210 T 22-04-2016 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 399 4.1E-141 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 22-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 PIRSF PIRSF000429 1 402 1.5E-130 T 22-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 22-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Gene3D G3DSA:3.40.47.10 3 124 2.2E-66 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 Gene3D G3DSA:3.40.47.10 199 282 2.2E-66 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 2 401 7.4E-183 T 22-04-2016 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 MED134_RS11525 37b433e1fc45489c0fb7433a773c7d23 403 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 22-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MED134_RS01190 86c34ba2c7d8e50d15f6687fd477ead0 188 Gene3D G3DSA:3.40.50.300 30 110 8.0E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01190 86c34ba2c7d8e50d15f6687fd477ead0 188 Pfam PF00406 Adenylate kinase 30 118 1.9E-9 T 22-04-2016 MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 Pfam PF00482 Type II secretion system (T2SS), protein F 43 165 1.8E-19 T 22-04-2016 IPR018076 Type II secretion system F domain MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 Pfam PF00482 Type II secretion system (T2SS), protein F 245 367 8.6E-20 T 22-04-2016 IPR018076 Type II secretion system F domain MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 PANTHER PTHR30012 21 376 1.6E-86 T 22-04-2016 MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 PRINTS PR00812 Bacterial general secretion pathway protein F signature 137 165 7.5E-12 T 22-04-2016 IPR003004 GspF/PilC family MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 PRINTS PR00812 Bacterial general secretion pathway protein F signature 340 354 7.5E-12 T 22-04-2016 IPR003004 GspF/PilC family MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 PRINTS PR00812 Bacterial general secretion pathway protein F signature 356 375 7.5E-12 T 22-04-2016 IPR003004 GspF/PilC family MED134_RS08315 bfb53a36e2cee239cf46bbac0f5f690b 376 PANTHER PTHR30012:SF0 21 376 1.6E-86 T 22-04-2016 MED134_RS02845 e0fbce4ed762f4030d824ffc94e176a9 101 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 101 2.8E-13 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS02845 e0fbce4ed762f4030d824ffc94e176a9 101 Gene3D G3DSA:3.30.160.100 1 100 2.8E-17 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS02845 e0fbce4ed762f4030d824ffc94e176a9 101 SUPERFAMILY SSF69754 1 94 3.14E-18 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS02845 e0fbce4ed762f4030d824ffc94e176a9 101 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 97 4.5E-14 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 Pfam PF04932 O-Antigen ligase 202 376 1.2E-15 T 22-04-2016 IPR007016 O-antigen ligase-related MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 Gene3D G3DSA:1.25.40.10 536 779 3.0E-25 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SUPERFAMILY SSF48452 536 667 1.64E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SMART SM00028 720 753 13.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SMART SM00028 531 563 390.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SMART SM00028 755 792 180.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SMART SM00028 633 667 450.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SMART SM00028 686 719 6.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 SUPERFAMILY SSF48452 651 781 1.77E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 PANTHER PTHR23083 686 779 1.1E-16 T 22-04-2016 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 PANTHER PTHR23083 41 54 1.1E-16 T 22-04-2016 MED134_RS05675 adfa8ed43573056000c6ce8d09418657 798 PANTHER PTHR23083 543 667 1.1E-16 T 22-04-2016 MED134_RS04160 8c066d2c6a3bea0b48567f4c44afa548 104 PANTHER PTHR10438:SF261 1 104 1.5E-20 T 22-04-2016 MED134_RS04160 8c066d2c6a3bea0b48567f4c44afa548 104 Gene3D G3DSA:3.40.30.10 2 102 1.9E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04160 8c066d2c6a3bea0b48567f4c44afa548 104 SUPERFAMILY SSF52833 2 101 1.33E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04160 8c066d2c6a3bea0b48567f4c44afa548 104 Pfam PF00085 Thioredoxin 3 98 1.9E-20 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 MED134_RS04160 8c066d2c6a3bea0b48567f4c44afa548 104 PANTHER PTHR10438 1 104 1.5E-20 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 SUPERFAMILY SSF53383 5 421 5.19E-123 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS07105 619353653d229ba856d120e2f894aebe 430 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 421 1.8E-140 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 6 421 9.2E-192 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 PANTHER PTHR11808 265 426 5.2E-220 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 PANTHER PTHR11808 5 235 5.2E-220 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 Gene3D G3DSA:3.40.640.10 5 286 4.0E-117 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 Gene3D G3DSA:3.90.1150.10 288 424 7.2E-50 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 PANTHER PTHR11808:SF12 265 426 5.2E-220 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 PANTHER PTHR11808:SF12 5 235 5.2E-220 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 MED134_RS07105 619353653d229ba856d120e2f894aebe 430 PIRSF PIRSF001434 1 425 3.3E-130 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 PANTHER PTHR18964 1 238 6.5E-44 T 22-04-2016 MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 SUPERFAMILY SSF53067 1 244 3.29E-38 T 22-04-2016 MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 Pfam PF00480 ROK family 4 146 9.8E-22 T 22-04-2016 IPR000600 ROK family MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 Gene3D G3DSA:3.30.420.40 105 245 1.9E-32 T 22-04-2016 MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 Gene3D G3DSA:3.30.420.40 2 104 1.5E-37 T 22-04-2016 MED134_RS02930 f640af369d40c8921115c4d1ddafa57f 247 PANTHER PTHR18964:SF138 1 238 6.5E-44 T 22-04-2016 MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Gene3D G3DSA:3.40.50.300 278 465 1.7E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 PANTHER PTHR30580 1 192 2.1E-230 T 22-04-2016 MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 PANTHER PTHR30580 211 816 2.1E-230 T 22-04-2016 MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 SMART SM00487 276 476 4.5E-17 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 SUPERFAMILY SSF52540 473 528 3.14E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 SUPERFAMILY SSF52540 591 688 3.14E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 SUPERFAMILY SSF52540 294 446 3.14E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Pfam PF00271 Helicase conserved C-terminal domain 609 676 2.1E-7 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Gene3D G3DSA:3.40.50.300 577 721 3.9E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Gene3D G3DSA:3.40.50.300 492 516 3.9E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 SMART SM00490 580 677 3.4E-9 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Hamap MF_00983 Probable primosomal protein N' [priA]. 7 818 23.36 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 Pfam PF00270 DEAD/DEAH box helicase 283 448 4.8E-12 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS02230 3fad52578fa55cc48de7d2082cda296a 818 TIGRFAM TIGR00595 priA: primosomal protein N' 302 816 2.1E-179 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Gene3D G3DSA:1.20.58.100 503 617 1.9E-31 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 315 4.8E-7 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 57 4.8E-7 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 220 245 4.8E-7 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PANTHER PTHR11632:SF53 3 670 0.0 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 36 669 8.5E-284 T 22-04-2016 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|UniPathway: UPA00223 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 SUPERFAMILY SSF46977 522 669 2.62E-36 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PANTHER PTHR11632 3 670 0.0 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 SUPERFAMILY SSF51905 434 487 1.15E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 SUPERFAMILY SSF51905 35 277 1.15E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Gene3D G3DSA:3.90.700.10 267 424 9.5E-16 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Gene3D G3DSA:3.50.50.60 426 478 2.7E-74 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Gene3D G3DSA:3.50.50.60 24 266 2.7E-74 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 455 1.8E-7 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 36 55 1.8E-7 T 22-04-2016 MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Pfam PF00890 FAD binding domain 35 469 1.7E-56 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 SUPERFAMILY SSF56425 261 431 4.19E-29 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain MED134_RS10995 60527352853ac30f980c1457c13d93a4 670 Pfam PF02910 Fumarate reductase flavoprotein C-term 531 669 1.9E-36 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 PANTHER PTHR26402 6 119 4.9E-17 T 22-04-2016 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 Pfam PF04397 LytTr DNA-binding domain 145 231 5.7E-18 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 Gene3D G3DSA:2.40.50.40 132 201 1.3E-19 T 22-04-2016 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 SMART SM00850 141 232 6.4E-21 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 Gene3D G3DSA:3.40.50.2300 8 125 1.3E-21 T 22-04-2016 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 PANTHER PTHR26402:SF527 6 119 4.9E-17 T 22-04-2016 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 SUPERFAMILY SSF52172 9 129 3.13E-22 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 Pfam PF00072 Response regulator receiver domain 10 114 4.6E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS02225 bc32ce920dce39294c61a34c6b89b281 233 SMART SM00448 6 114 9.5E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 PANTHER PTHR18895:SF73 27 129 5.0E-48 T 22-04-2016 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 PANTHER PTHR18895:SF73 146 245 5.0E-48 T 22-04-2016 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 Pfam PF05175 Methyltransferase small domain 40 123 8.2E-15 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 4 272 49.205 T 22-04-2016 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 SUPERFAMILY SSF53335 39 202 3.8E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 112 118 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 PANTHER PTHR18895 27 129 5.0E-48 T 22-04-2016 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 PANTHER PTHR18895 146 245 5.0E-48 T 22-04-2016 MED134_RS07585 48ff5080d5cbd1d6ffd24d2b6a236702 272 Gene3D G3DSA:3.40.50.150 25 261 8.5E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 PANTHER PTHR24220:SF567 3 237 5.2E-104 T 22-04-2016 MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 PANTHER PTHR24220 3 237 5.2E-104 T 22-04-2016 MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 Gene3D G3DSA:3.40.50.300 1 235 2.8E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 SMART SM00382 26 215 1.0E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 SUPERFAMILY SSF52540 1 234 6.39E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 Pfam PF00005 ABC transporter 17 165 1.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS11935 9e3ec7bce97fb4bf3672988d17456cfc 253 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 SMART SM00382 26 237 8.9E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 SMART SM00382 352 525 8.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 SUPERFAMILY SSF52540 304 532 8.15E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Pfam PF00005 ABC transporter 343 473 3.5E-20 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Pfam PF00005 ABC transporter 18 192 1.3E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Pfam PF12848 ABC transporter 231 311 8.5E-23 T 22-04-2016 IPR032781 ABC-transporter extension domain MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 PANTHER PTHR19211 1 583 1.2E-253 T 22-04-2016 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 SUPERFAMILY SSF52540 5 244 1.47E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 PANTHER PTHR19211:SF60 1 583 1.2E-253 T 22-04-2016 MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Gene3D G3DSA:3.40.50.300 125 279 7.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Gene3D G3DSA:3.40.50.300 1 88 7.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06070 0ba13c39a2ced042586d3e328ae83b0d 636 Gene3D G3DSA:3.40.50.300 325 545 3.3E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 Pfam PF10728 Domain of unknown function (DUF2520) 123 246 3.7E-32 T 22-04-2016 IPR018931 Domain of unknown function DUF2520 MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 SUPERFAMILY SSF51735 4 154 1.65E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 87 9.0E-6 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 Gene3D G3DSA:3.40.50.720 2 154 2.4E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 SUPERFAMILY SSF48179 157 253 1.02E-26 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 Gene3D G3DSA:1.10.1040.20 155 249 8.1E-32 T 22-04-2016 IPR018931 Domain of unknown function DUF2520 MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 PANTHER PTHR40459 1 249 1.1E-15 T 22-04-2016 MED134_RS00250 1c262cf67d1658f7588a1445ab02b8d1 255 PANTHER PTHR40459:SF1 1 249 1.1E-15 T 22-04-2016 MED134_RS14040 cd44756b099a14b9dfce7901f0f1fc46 126 Pfam PF12680 SnoaL-like domain 14 108 4.8E-9 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain MED134_RS14040 cd44756b099a14b9dfce7901f0f1fc46 126 SUPERFAMILY SSF54427 6 116 9.1E-21 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS14040 cd44756b099a14b9dfce7901f0f1fc46 126 Gene3D G3DSA:3.10.450.50 13 115 9.4E-7 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 PANTHER PTHR22855 5 542 7.5E-259 T 22-04-2016 MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 SUPERFAMILY SSF52096 269 535 2.18E-80 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 SUPERFAMILY SSF52096 12 256 1.74E-59 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 PANTHER PTHR22855:SF13 5 542 7.5E-259 T 22-04-2016 MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 Gene3D G3DSA:3.90.226.10 272 534 3.4E-83 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 Gene3D G3DSA:3.90.226.10 18 255 1.2E-65 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS04805 c21dbbc7b22ced4925caf9b9131ea871 542 Pfam PF01039 Carboxyl transferase domain 38 533 1.3E-142 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS00590 16a2a39a3b73b90fd36a034664b114ee 120 SMART SM00448 1 105 3.3E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00590 16a2a39a3b73b90fd36a034664b114ee 120 SUPERFAMILY SSF52172 3 113 1.57E-26 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS00590 16a2a39a3b73b90fd36a034664b114ee 120 Gene3D G3DSA:3.40.50.2300 3 114 1.6E-28 T 22-04-2016 MED134_RS00590 16a2a39a3b73b90fd36a034664b114ee 120 Pfam PF00072 Response regulator receiver domain 3 105 2.0E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00590 16a2a39a3b73b90fd36a034664b114ee 120 PANTHER PTHR26402 3 109 6.7E-26 T 22-04-2016 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 22-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 SUPERFAMILY SSF54534 81 155 1.23E-19 T 22-04-2016 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 Pfam PF03449 Transcription elongation factor, N-terminal 6 75 8.4E-29 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 SUPERFAMILY SSF46557 4 79 4.32E-25 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 155 8.2E-55 T 22-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 156 2.6E-24 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 Gene3D G3DSA:3.10.50.30 77 156 2.1E-26 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 156 29.738 T 22-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 Gene3D G3DSA:1.10.287.180 3 76 9.7E-30 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 PIRSF PIRSF006092 1 158 1.1E-50 T 22-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MED134_RS10005 9154c40620020aa27093f22e23f9aded 158 PANTHER PTHR30437 1 155 7.7E-60 T 22-04-2016 MED134_RS06800 62d775bf7cdfce6219d49ff8535a1583 128 SUPERFAMILY SSF54211 5 128 3.68E-48 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS06800 62d775bf7cdfce6219d49ff8535a1583 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 30.092 T 22-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid MED134_RS06800 62d775bf7cdfce6219d49ff8535a1583 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 1.5E-48 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MED134_RS06800 62d775bf7cdfce6219d49ff8535a1583 128 Gene3D G3DSA:3.30.230.10 4 128 2.7E-51 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS06800 62d775bf7cdfce6219d49ff8535a1583 128 PANTHER PTHR21569 8 128 2.9E-68 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MED134_RS08675 c4bb84d5b2059eb7b2f015733658d5ec 226 Pfam PF02602 Uroporphyrinogen-III synthase HemD 35 213 6.3E-33 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08675 c4bb84d5b2059eb7b2f015733658d5ec 226 Gene3D G3DSA:3.40.50.10090 131 218 4.5E-16 T 22-04-2016 MED134_RS08675 c4bb84d5b2059eb7b2f015733658d5ec 226 Gene3D G3DSA:3.40.50.10090 40 130 3.7E-25 T 22-04-2016 MED134_RS08675 c4bb84d5b2059eb7b2f015733658d5ec 226 SUPERFAMILY SSF69618 3 218 2.22E-30 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS08675 c4bb84d5b2059eb7b2f015733658d5ec 226 PANTHER PTHR12390 46 225 1.0E-21 T 22-04-2016 MED134_RS13215 76ab473842f02300ddbe97806330ad58 434 Pfam PF12698 ABC-2 family transporter protein 19 408 4.3E-64 T 22-04-2016 MED134_RS13215 76ab473842f02300ddbe97806330ad58 434 SUPERFAMILY SSF53850 49 182 1.63E-35 T 22-04-2016 MED134_RS13215 76ab473842f02300ddbe97806330ad58 434 Gene3D G3DSA:3.40.190.10 42 147 1.5E-29 T 22-04-2016 MED134_RS13215 76ab473842f02300ddbe97806330ad58 434 PANTHER PTHR41312 2 252 7.3E-43 T 22-04-2016 MED134_RS13215 76ab473842f02300ddbe97806330ad58 434 PANTHER PTHR41312 272 434 7.3E-43 T 22-04-2016 MED134_RS11895 5dfdfec31c821bea3aeec80f9432701a 332 SUPERFAMILY SSF52518 3 322 2.85E-96 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11895 5dfdfec31c821bea3aeec80f9432701a 332 Gene3D G3DSA:3.40.50.970 2 323 2.5E-125 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11895 5dfdfec31c821bea3aeec80f9432701a 332 PANTHER PTHR11516 3 322 9.2E-135 T 22-04-2016 MED134_RS11895 5dfdfec31c821bea3aeec80f9432701a 332 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 7 320 2.1E-127 T 22-04-2016 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MED134_RS11895 5dfdfec31c821bea3aeec80f9432701a 332 Pfam PF00676 Dehydrogenase E1 component 16 312 8.9E-90 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Hamap MF_01113 DNA polymerase IV [dinB]. 6 364 36.965 T 22-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Gene3D G3DSA:3.30.70.270 70 167 1.1E-33 T 22-04-2016 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Pfam PF00817 impB/mucB/samB family 12 158 1.2E-49 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 SUPERFAMILY SSF56672 6 238 3.74E-88 T 22-04-2016 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Pfam PF11799 impB/mucB/samB family C-terminal domain 239 347 1.5E-19 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Gene3D G3DSA:1.10.150.20 169 239 2.1E-19 T 22-04-2016 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Gene3D G3DSA:3.30.1490.100 245 350 1.3E-31 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 Pfam PF11798 IMS family HHH motif 170 201 4.3E-8 T 22-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 PANTHER PTHR11076 9 354 5.3E-147 T 22-04-2016 MED134_RS10415 bba71c860eb983d09bd09da41741de7c 370 SUPERFAMILY SSF100879 242 342 1.88E-28 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 PANTHER PTHR30294 1 261 3.6E-45 T 22-04-2016 MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 Pfam PF12679 ABC-2 family transporter protein 53 240 2.1E-13 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 TIGRFAM TIGR03521 GldG: gliding-associated putative ABC transporter substrate-binding component GldG 256 808 3.6E-204 T 22-04-2016 IPR019863 Gliding-associated putative ABC transporter substrate-binding GldG MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 TIGRFAM TIGR03518 ABC_perm_GldF: gliding motility-associated ABC transporter permease protein GldF 2 240 3.5E-102 T 22-04-2016 IPR019860 Gliding motility-associated ABC transporter permease protein GldF MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 Pfam PF09822 ABC-type uncharacterized transport system 275 563 2.0E-63 T 22-04-2016 IPR019196 ABC-type uncharacterised transport system MED134_RS03130 70e56c6de8c55b217dcf750a8924b1a6 809 PANTHER PTHR30294:SF5 1 261 3.6E-45 T 22-04-2016 MED134_RS04685 0be49bc17abcab5abdb000b23942a420 253 Pfam PF01734 Patatin-like phospholipase 5 162 2.1E-25 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 MED134_RS04685 0be49bc17abcab5abdb000b23942a420 253 Gene3D G3DSA:3.40.1090.10 5 173 1.1E-10 T 22-04-2016 MED134_RS04685 0be49bc17abcab5abdb000b23942a420 253 SUPERFAMILY SSF52151 1 248 6.02E-53 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS04685 0be49bc17abcab5abdb000b23942a420 253 PANTHER PTHR14226:SF37 2 249 1.7E-56 T 22-04-2016 MED134_RS04685 0be49bc17abcab5abdb000b23942a420 253 PANTHER PTHR14226 2 249 1.7E-56 T 22-04-2016 MED134_RS09705 fcdb25df1d1dfe9a94b6b0ba70778706 787 Gene3D G3DSA:3.40.630.10 27 303 1.8E-54 T 22-04-2016 MED134_RS09705 fcdb25df1d1dfe9a94b6b0ba70778706 787 SUPERFAMILY SSF53187 34 303 6.56E-54 T 22-04-2016 MED134_RS09705 fcdb25df1d1dfe9a94b6b0ba70778706 787 Pfam PF04389 Peptidase family M28 103 295 7.8E-38 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS09705 fcdb25df1d1dfe9a94b6b0ba70778706 787 PANTHER PTHR12147:SF6 7 468 1.4E-47 T 22-04-2016 MED134_RS09705 fcdb25df1d1dfe9a94b6b0ba70778706 787 PANTHER PTHR12147 7 468 1.4E-47 T 22-04-2016 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 Pfam PF07728 AAA domain (dynein-related subfamily) 757 839 1.1E-8 T 22-04-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 Gene3D G3DSA:3.10.590.10 192 308 1.2E-7 T 22-04-2016 IPR002740 EVE domain MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 SUPERFAMILY SSF52540 464 588 3.8E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 SUPERFAMILY SSF52540 760 847 3.8E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 Gene3D G3DSA:3.40.50.300 764 844 4.6E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 Gene3D G3DSA:3.40.50.300 458 591 4.6E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 PANTHER PTHR37291:SF1 714 915 5.3E-47 T 22-04-2016 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 PANTHER PTHR37291:SF1 120 669 5.3E-47 T 22-04-2016 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 PANTHER PTHR37291 714 915 5.3E-47 T 22-04-2016 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 PANTHER PTHR37291 120 669 5.3E-47 T 22-04-2016 MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 SUPERFAMILY SSF88697 191 330 3.69E-11 T 22-04-2016 IPR015947 PUA-like domain MED134_RS00325 46266fccf529a08871564b0dbb981ac2 936 Pfam PF01878 EVE domain 193 317 1.6E-12 T 22-04-2016 IPR002740 EVE domain MED134_RS12860 8eb07b7cfd65b80f0958b03ac70a0c6f 440 Gene3D G3DSA:3.90.230.10 192 438 1.1E-35 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS12860 8eb07b7cfd65b80f0958b03ac70a0c6f 440 SUPERFAMILY SSF55920 195 436 1.83E-34 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS12860 8eb07b7cfd65b80f0958b03ac70a0c6f 440 PANTHER PTHR10804:SF109 178 372 4.3E-21 T 22-04-2016 MED134_RS12860 8eb07b7cfd65b80f0958b03ac70a0c6f 440 PANTHER PTHR10804 178 372 4.3E-21 T 22-04-2016 MED134_RS12860 8eb07b7cfd65b80f0958b03ac70a0c6f 440 Pfam PF00557 Metallopeptidase family M24 201 422 2.6E-24 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 SUPERFAMILY SSF51735 1 199 3.4E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 163 2.4E-12 T 22-04-2016 MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 Gene3D G3DSA:3.40.50.720 1 198 3.1E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 1.2E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.2E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 1.2E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11530 2b7e8c9e40eb58843731b22fa1193b9a 200 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 1.2E-5 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 PANTHER PTHR30349:SF26 44 415 9.1E-71 T 22-04-2016 MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 PANTHER PTHR30349 44 415 9.1E-71 T 22-04-2016 MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 SUPERFAMILY SSF56349 115 394 1.06E-42 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 Pfam PF13102 Phage integrase SAM-like domain 15 170 2.7E-26 T 22-04-2016 IPR025269 Phage integrase SAM-like domain MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 Pfam PF00589 Phage integrase family 256 390 5.6E-15 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS00760 34dfbfedb95188038c51de5dee041bde 417 Gene3D G3DSA:1.10.443.10 243 393 5.0E-30 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383:SF14 120 174 3.1E-42 T 22-04-2016 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383:SF14 211 225 3.1E-42 T 22-04-2016 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383:SF14 249 284 3.1E-42 T 22-04-2016 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383:SF14 438 485 3.1E-42 T 22-04-2016 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 SUPERFAMILY SSF51306 140 180 1.1E-26 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 142 158 7.5E-9 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 446 465 7.5E-9 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 SUPERFAMILY SSF51306 393 504 3.09E-20 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 Gene3D G3DSA:2.10.109.10 446 488 2.8E-45 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 Gene3D G3DSA:2.10.109.10 139 261 2.8E-45 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 SUPERFAMILY SSF51306 207 288 1.1E-26 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 126 279 1.0E-20 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 Pfam PF00717 Peptidase S24-like 149 275 1.3E-9 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383 120 174 3.1E-42 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383 211 225 3.1E-42 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383 249 284 3.1E-42 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 PANTHER PTHR12383 438 485 3.1E-42 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MED134_RS05390 604c6ccb6b4d461d54ada507a142a04e 539 ProSitePatterns PS00760 Signal peptidases I lysine active site. 253 265 - T 22-04-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 Gene3D G3DSA:3.40.50.620 10 218 3.0E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 Gene3D G3DSA:3.40.50.620 252 260 3.0E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 SUPERFAMILY SSF52402 16 218 1.75E-63 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PIRSF PIRSF002936 8 310 5.6E-131 T 22-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 17 310 1.7E-127 T 22-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293 17 166 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293 186 219 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293 253 310 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293:SF6 17 166 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293:SF6 186 219 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 PANTHER PTHR23293:SF6 253 310 1.5E-73 T 22-04-2016 MED134_RS14485 2ea7f723458d59a9e8fd07a3eb3f8b9d 310 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 265 3.8E-50 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 129 145 - T 22-04-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 143 295 7.0E-5 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 SUPERFAMILY SSF55347 134 292 3.27E-39 T 22-04-2016 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 Gene3D G3DSA:3.40.50.720 1 142 1.3E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 318 32.076 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 SMART SM00859 3 126 4.2E-30 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 SUPERFAMILY SSF51735 1 149 6.56E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 320 1.4E-89 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 Gene3D G3DSA:3.30.360.10 143 292 2.7E-42 T 22-04-2016 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 PANTHER PTHR32338 1 324 1.1E-110 T 22-04-2016 MED134_RS11745 331013deb13e67532f37dae10a07fafc 324 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 126 1.7E-26 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 Gene3D G3DSA:3.30.300.70 2 72 2.5E-10 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 Pfam PF02576 Putative ribosome maturation factor RimP 19 150 3.2E-18 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 4 154 16.373 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 PANTHER PTHR33867:SF1 1 154 7.3E-22 T 22-04-2016 MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 PANTHER PTHR33867 1 154 7.3E-22 T 22-04-2016 MED134_RS11170 7368341444a7caa865afdbb3e45d094a 154 SUPERFAMILY SSF75420 3 75 3.27E-10 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 Hamap MF_00235 Adenylate kinase [adk]. 2 188 42.705 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 Gene3D G3DSA:3.40.50.300 3 186 1.6E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 Pfam PF00406 Adenylate kinase 6 165 2.1E-49 T 22-04-2016 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 SUPERFAMILY SSF52540 3 189 8.75E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PRINTS PR00094 Adenylate kinase signature 5 18 1.6E-24 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PRINTS PR00094 Adenylate kinase signature 82 98 1.6E-24 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PRINTS PR00094 Adenylate kinase signature 33 47 1.6E-24 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PRINTS PR00094 Adenylate kinase signature 152 166 1.6E-24 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PRINTS PR00094 Adenylate kinase signature 135 150 1.6E-24 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS12020 3573146c06098f73d5ba6d57723d7b5f 190 PANTHER PTHR23359 4 190 1.4E-69 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 MED134_RS07510 d487b246869d700b0b6cc9c813296392 218 Gene3D G3DSA:3.10.580.10 1 117 8.2E-10 T 22-04-2016 MED134_RS07510 d487b246869d700b0b6cc9c813296392 218 SUPERFAMILY SSF54631 1 116 6.6E-16 T 22-04-2016 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 PANTHER PTHR37326 12 336 3.9E-69 T 22-04-2016 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 Gene3D G3DSA:3.40.630.10 46 152 3.9E-20 T 22-04-2016 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 SUPERFAMILY SSF53187 42 320 3.97E-54 T 22-04-2016 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 PIRSF PIRSF039012 6 328 6.2E-74 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 PANTHER PTHR37326:SF1 12 336 3.9E-69 T 22-04-2016 MED134_RS08900 1a4ed5d3541cfacdeb4303c74539acd5 336 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 50 320 8.1E-52 T 22-04-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 Gene3D G3DSA:3.40.50.300 342 573 2.2E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 Pfam PF00664 ABC transporter transmembrane region 19 299 4.7E-35 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 SUPERFAMILY SSF90123 6 328 2.35E-63 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 SUPERFAMILY SSF52540 334 579 1.13E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 Pfam PF00005 ABC transporter 360 507 2.6E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 Gene3D G3DSA:1.20.1560.10 7 327 1.3E-60 T 22-04-2016 MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 SMART SM00382 369 555 5.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS02380 bfe12de7bbd6de8a3fb67c9fbb91507a 585 PANTHER PTHR24221 4 585 1.3E-181 T 22-04-2016 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 4 58 3.0E-11 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 108 181 6.0E-14 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 SMART SM01259 110 181 1.2E-34 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 SMART SM01259 1 60 1.5E-23 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 110 180 2.5E-27 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS11085 c72509720a2c9ae66a1c04d3dc9e1498 188 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 2 59 3.1E-23 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS12585 8b0b09c7bf218edce71d9f03c229ef65 86 Pfam PF02656 Domain of unknown function (DUF202) 16 78 1.1E-15 T 22-04-2016 IPR003807 Domain of unknown function DUF202 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 SUPERFAMILY SSF56176 356 438 4.36E-17 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Gene3D G3DSA:3.30.465.10 350 438 7.4E-21 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Pfam PF01595 Domain of unknown function DUF21 25 208 1.8E-35 T 22-04-2016 IPR002550 Domain of unknown function DUF21 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 TIGRFAM TIGR03520 GldE: gliding motility-associated protein GldE 26 438 4.1E-194 T 22-04-2016 IPR019862 Gliding motility-associated protein GldE MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Pfam PF03471 Transporter associated domain 357 438 1.6E-17 T 22-04-2016 IPR005170 Transporter-associated domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Gene3D G3DSA:3.10.580.10 209 349 2.7E-19 T 22-04-2016 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 SMART SM01091 356 440 1.4E-18 T 22-04-2016 IPR005170 Transporter-associated domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Pfam PF00571 CBS domain 225 277 4.5E-5 T 22-04-2016 IPR000644 CBS domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 Pfam PF00571 CBS domain 292 341 4.2E-7 T 22-04-2016 IPR000644 CBS domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 PANTHER PTHR22777 20 438 1.9E-109 T 22-04-2016 MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 SMART SM00116 232 281 0.37 T 22-04-2016 IPR000644 CBS domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 SMART SM00116 293 341 0.25 T 22-04-2016 IPR000644 CBS domain MED134_RS10205 122bfa4bd36ece39291acf5526fcdf31 440 SUPERFAMILY SSF54631 218 357 1.77E-32 T 22-04-2016 MED134_RS07135 aaf3c7d7075e3a872fd226281880b894 275 Pfam PF09697 Protein of unknown function (Porph_ging) 137 206 7.3E-22 T 22-04-2016 IPR005901 GLPGLI family protein MED134_RS07135 aaf3c7d7075e3a872fd226281880b894 275 TIGRFAM TIGR01200 GLPGLI: GLPGLI family protein 6 248 2.5E-64 T 22-04-2016 IPR005901 GLPGLI family protein MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 SUPERFAMILY SSF51905 3 157 4.75E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 SUPERFAMILY SSF51905 261 344 4.75E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PANTHER PTHR10617 5 328 8.8E-24 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 Gene3D G3DSA:3.50.50.60 3 160 2.1E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 Gene3D G3DSA:3.50.50.60 263 302 2.1E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PANTHER PTHR10617:SF101 5 328 8.8E-24 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 4.9E-10 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 296 4.9E-10 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 4.9E-10 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.9E-10 T 22-04-2016 MED134_RS02645 15326d5a2d64b186f2f65808ca723db5 372 Pfam PF01266 FAD dependent oxidoreductase 6 39 7.7E-7 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 3 397 35.831 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 Gene3D G3DSA:3.20.20.10 27 256 1.6E-65 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PANTHER PTHR11482:SF5 5 395 7.6E-133 T 22-04-2016 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 SUPERFAMILY SSF51419 14 268 2.04E-64 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 284 374 8.0E-14 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 Gene3D G3DSA:2.40.37.10 257 399 3.0E-43 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 354 367 2.4E-17 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 46 64 2.4E-17 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 78 2.4E-17 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 256 275 2.4E-17 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 173 186 2.4E-17 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PANTHER PTHR11482 5 395 7.6E-133 T 22-04-2016 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 SUPERFAMILY SSF50621 247 398 3.35E-46 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 27 266 1.1E-44 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 46 64 - T 22-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 64 81 2.9E-22 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 148 157 2.9E-22 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 364 386 2.9E-22 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 284 302 2.9E-22 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03330 14dbdeca69da9ad910eba29e9f4c0916 401 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 3 396 1.1E-114 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 SUPERFAMILY SSF54814 177 292 1.31E-39 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 161 2.4E-19 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 3.5E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 57 72 3.5E-7 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 PANTHER PTHR11649 3 293 3.3E-103 T 22-04-2016 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 SUPERFAMILY SSF52540 10 199 1.1E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 Pfam PF01926 50S ribosome-binding GTPase 8 121 1.8E-20 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 Gene3D G3DSA:3.30.300.20 188 288 2.3E-38 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 Pfam PF07650 KH domain 204 280 5.2E-18 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 PANTHER PTHR11649:SF3 3 293 3.3E-103 T 22-04-2016 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 TIGRFAM TIGR00436 era: GTP-binding protein Era 6 274 9.0E-77 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 Hamap MF_00367 GTPase Era [era]. 3 291 33.735 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 MED134_RS06020 0bec90f195eee4340c1ebbc97e41e954 294 Gene3D G3DSA:3.40.50.300 8 187 3.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 Pfam PF08443 RimK-like ATP-grasp domain 98 286 3.5E-67 T 22-04-2016 IPR013651 ATP-grasp fold, RimK-type MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 Gene3D G3DSA:3.40.50.20 8 102 2.2E-11 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 PANTHER PTHR21621:SF0 1 290 6.9E-103 T 22-04-2016 MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 PANTHER PTHR21621 1 290 6.9E-103 T 22-04-2016 MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 Gene3D G3DSA:3.30.470.20 174 276 3.3E-36 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 SUPERFAMILY SSF56059 99 288 5.22E-48 T 22-04-2016 MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 Gene3D G3DSA:3.30.1490.20 103 173 2.8E-5 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS08905 11d4626a2886e6f1b0312732d7aba109 290 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 286 9.2E-77 T 22-04-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 MED134_RS06575 4ed89e657d0e93485d738ec9ee031f45 200 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 6 189 1.4E-62 T 22-04-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated MED134_RS06575 4ed89e657d0e93485d738ec9ee031f45 200 Gene3D G3DSA:3.90.550.10 8 167 9.1E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS06575 4ed89e657d0e93485d738ec9ee031f45 200 PANTHER PTHR36529 4 189 2.2E-33 T 22-04-2016 MED134_RS06575 4ed89e657d0e93485d738ec9ee031f45 200 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 57 157 3.1E-31 T 22-04-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated MED134_RS06575 4ed89e657d0e93485d738ec9ee031f45 200 SUPERFAMILY SSF53448 8 192 3.38E-32 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 Gene3D G3DSA:3.40.5.10 1 49 6.0E-22 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 SUPERFAMILY SSF55653 60 148 2.75E-25 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 SUPERFAMILY SSF55658 1 57 4.01E-17 T 22-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.2E-38 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.4E-20 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 23.713 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 PANTHER PTHR21368 1 150 9.3E-44 T 22-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 2.1E-26 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal MED134_RS02210 998d8b1f2539dd28b43b90ed0a58cb62 150 Gene3D G3DSA:3.10.430.100 62 148 6.0E-27 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 SUPERFAMILY SSF53822 63 343 1.85E-63 T 22-04-2016 IPR028082 Periplasmic binding protein-like I MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 Gene3D G3DSA:1.10.260.40 6 56 2.5E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 SMART SM00354 4 74 4.4E-16 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 Gene3D G3DSA:3.40.50.2300 57 179 1.5E-40 T 22-04-2016 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 Gene3D G3DSA:3.40.50.2300 180 320 8.5E-39 T 22-04-2016 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 6.9E-10 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 Pfam PF13377 Periplasmic binding protein-like domain 176 342 1.9E-27 T 22-04-2016 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 PANTHER PTHR30146 3 344 1.5E-92 T 22-04-2016 MED134_RS10600 da207da72484af0e00bdf24b36b73577 346 SUPERFAMILY SSF47413 4 62 9.85E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS03850 008577d97bf3fdfaa9034e37c7978bb7 151 PANTHER PTHR33202 20 145 1.4E-26 T 22-04-2016 MED134_RS03850 008577d97bf3fdfaa9034e37c7978bb7 151 Pfam PF01475 Ferric uptake regulator family 24 144 4.6E-27 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MED134_RS03850 008577d97bf3fdfaa9034e37c7978bb7 151 SUPERFAMILY SSF46785 19 146 9.67E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS03850 008577d97bf3fdfaa9034e37c7978bb7 151 Gene3D G3DSA:1.10.10.10 19 94 2.9E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.398 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 43 1.0E-12 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 Pfam PF00468 Ribosomal protein L34 3 45 6.2E-22 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 22-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.5E-20 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03270 cf30436eddb30d22dc2b138d9b7f2866 53 PANTHER PTHR14503 1 47 2.7E-21 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 Gene3D G3DSA:2.30.40.10 422 462 3.0E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 Gene3D G3DSA:2.30.40.10 31 90 3.0E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271:SF33 1 256 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271:SF33 296 325 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271:SF33 352 462 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 SUPERFAMILY SSF51338 422 459 1.02E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 SUPERFAMILY SSF51338 27 89 1.02E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 Gene3D G3DSA:3.20.20.140 91 245 6.0E-44 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 Gene3D G3DSA:3.20.20.140 283 417 6.0E-44 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 SUPERFAMILY SSF51556 88 246 9.28E-40 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 SUPERFAMILY SSF51556 284 410 9.28E-40 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271 1 256 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271 296 325 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 PANTHER PTHR11271 352 462 2.0E-14 T 22-04-2016 MED134_RS03300 501342d5a62d0a0ee24331936a23617c 463 Pfam PF01979 Amidohydrolase family 85 459 1.0E-12 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS13965 c5b64050af8cfbf3674d4d6bb9c06f6f 179 PANTHER PTHR30543:SF6 1 179 2.5E-32 T 22-04-2016 MED134_RS13965 c5b64050af8cfbf3674d4d6bb9c06f6f 179 PANTHER PTHR30543 1 179 2.5E-32 T 22-04-2016 MED134_RS13965 c5b64050af8cfbf3674d4d6bb9c06f6f 179 SUPERFAMILY SSF52218 4 174 1.84E-33 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS13965 c5b64050af8cfbf3674d4d6bb9c06f6f 179 Pfam PF03358 NADPH-dependent FMN reductase 4 129 2.1E-23 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MED134_RS13965 c5b64050af8cfbf3674d4d6bb9c06f6f 179 Gene3D G3DSA:3.40.50.360 3 177 1.6E-32 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 Gene3D G3DSA:1.10.10.10 478 535 1.3E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 ProSitePatterns PS00622 LuxR-type HTH domain signature. 496 523 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 SUPERFAMILY SSF46894 473 534 1.16E-17 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 Pfam PF07695 7TM diverse intracellular signalling 236 436 9.8E-15 T 22-04-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 Pfam PF00196 Bacterial regulatory proteins, luxR family 481 534 6.4E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 Pfam PF07696 7TMR-DISM extracellular 2 94 209 3.0E-7 T 22-04-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 SMART SM00421 479 536 2.8E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 512 524 2.9E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 482 496 2.9E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS08010 b0953c6e83cef20f7d1ed5c77d551f64 537 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 496 512 2.9E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 Pfam PF02311 AraC-like ligand binding domain 29 79 1.6E-5 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 Gene3D G3DSA:1.10.10.60 225 274 1.2E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 SUPERFAMILY SSF46689 224 274 2.33E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 SMART SM00342 188 272 4.0E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 PANTHER PTHR11019:SF65 29 274 9.8E-29 T 22-04-2016 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 Gene3D G3DSA:1.10.10.60 170 224 1.8E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 PANTHER PTHR11019 29 274 9.8E-29 T 22-04-2016 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 Pfam PF12833 Helix-turn-helix domain 194 273 2.2E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 268 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 SUPERFAMILY SSF51182 26 92 1.72E-9 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 SUPERFAMILY SSF46689 172 222 1.34E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS07790 48618af45a5b3ffd07b34ff06e3441ed 275 Gene3D G3DSA:2.60.120.10 14 98 3.2E-11 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 Gene3D G3DSA:3.40.50.1440 21 223 3.3E-78 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PANTHER PTHR30314 1 373 1.0E-138 T 22-04-2016 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 ProSitePatterns PS01134 FtsZ protein signature 1. 51 85 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 SMART SM00865 215 333 1.0E-27 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PRINTS PR00423 Cell division protein FtsZ signature 196 218 7.5E-36 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PRINTS PR00423 Cell division protein FtsZ signature 106 126 7.5E-36 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PRINTS PR00423 Cell division protein FtsZ signature 219 240 7.5E-36 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PRINTS PR00423 Cell division protein FtsZ signature 134 155 7.5E-36 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 PANTHER PTHR30314:SF3 1 373 1.0E-138 T 22-04-2016 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 SUPERFAMILY SSF52490 21 210 6.41E-57 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 Gene3D G3DSA:3.30.1330.20 224 330 4.8E-35 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 SUPERFAMILY SSF55307 215 333 2.52E-31 T 22-04-2016 IPR008280 Tubulin/FtsZ, C-terminal MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 15 344 9.9E-104 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 Pfam PF12327 FtsZ family, C-terminal domain 229 324 1.1E-19 T 22-04-2016 IPR024757 Cell division protein FtsZ, C-terminal MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 ProSitePatterns PS01135 FtsZ protein signature 2. 105 126 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 16 389 33.04 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 21 181 7.7E-38 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS12550 3be441db3ba78fabb20d90dd4e4a437f 671 SMART SM00864 20 212 3.9E-91 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 MED134_RS07960 60e3b1d53923101ee9163b654a7f4ca4 67 Gene3D G3DSA:1.10.260.40 1 65 1.3E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS07960 60e3b1d53923101ee9163b654a7f4ca4 67 SMART SM00530 6 62 4.3E-4 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS07960 60e3b1d53923101ee9163b654a7f4ca4 67 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 9.3E-25 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS07960 60e3b1d53923101ee9163b654a7f4ca4 67 SUPERFAMILY SSF47413 2 65 5.35E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS07960 60e3b1d53923101ee9163b654a7f4ca4 67 PANTHER PTHR37301 2 65 3.4E-32 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815:SF11 693 880 8.5E-114 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 Pfam PF01103 Surface antigen 504 880 1.6E-29 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815 693 880 8.5E-114 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 Gene3D G3DSA:2.40.160.50 433 880 7.4E-53 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 Pfam PF07244 Surface antigen variable number repeat 296 381 3.3E-13 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 Pfam PF07244 Surface antigen variable number repeat 385 460 1.1E-10 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 Pfam PF07244 Surface antigen variable number repeat 206 293 4.3E-10 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PIRSF PIRSF006076 6 880 1.3E-186 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815:SF11 503 656 8.5E-114 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815:SF11 20 487 8.5E-114 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815 503 656 8.5E-114 T 22-04-2016 MED134_RS07530 39d78db9b24b0bc89963e887111d6de7 880 PANTHER PTHR12815 20 487 8.5E-114 T 22-04-2016 MED134_RS13500 aca0b424cfba84a36376b9bb7865690f 91 SUPERFAMILY SSF54736 16 90 2.35E-17 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MED134_RS13500 aca0b424cfba84a36376b9bb7865690f 91 Gene3D G3DSA:3.30.1390.10 2 89 1.5E-21 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MED134_RS13500 aca0b424cfba84a36376b9bb7865690f 91 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 17 84 1.7E-20 T 22-04-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Gene3D G3DSA:3.40.50.620 11 196 2.1E-138 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Gene3D G3DSA:3.40.50.620 459 722 2.1E-138 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 SUPERFAMILY SSF50677 228 411 6.38E-29 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Pfam PF08264 Anticodon-binding domain of tRNA 770 921 8.1E-31 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 SUPERFAMILY SSF52374 455 732 1.24E-123 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 SUPERFAMILY SSF52374 10 200 1.24E-123 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Gene3D G3DSA:1.10.730.10 723 913 1.2E-46 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 43 54 5.9E-17 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 453 468 5.9E-17 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 601 614 5.9E-17 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 642 651 5.9E-17 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1132 13.406 T 22-04-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 SUPERFAMILY SSF47323 738 982 1.87E-51 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946 435 545 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946 582 1025 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946 2 257 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946 304 418 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946:SF87 435 545 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946:SF87 582 1025 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946:SF87 2 257 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 PANTHER PTHR11946:SF87 304 418 0.0 T 22-04-2016 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Gene3D G3DSA:3.90.740.10 237 458 2.7E-44 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 718 1.4E-150 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08865 26f6472eab36e9dd732449d4c3d7e5a1 1135 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 932 6.8E-296 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 215 248 300.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 389 422 260.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 47 80 190.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 82 115 0.07 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 116 149 470.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 427 460 110.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SMART SM00028 321 354 0.0019 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Pfam PF13181 Tetratricopeptide repeat 323 354 2.9E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Pfam PF13181 Tetratricopeptide repeat 428 458 0.18 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SUPERFAMILY SSF48452 51 172 5.26E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 PANTHER PTHR23083 60 279 4.8E-35 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 PANTHER PTHR23083 318 459 4.8E-35 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Pfam PF13432 Tetratricopeptide repeat 364 413 7.2E-5 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Pfam PF13432 Tetratricopeptide repeat 88 139 2.4E-4 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SUPERFAMILY SSF81901 191 278 6.8E-19 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 SUPERFAMILY SSF81901 319 456 6.8E-19 T 22-04-2016 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Gene3D G3DSA:1.25.40.10 306 457 1.1E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09460 ea6b1cd8f6fa7c558e73f2ad6b1b4425 460 Gene3D G3DSA:1.25.40.10 49 283 6.3E-26 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Pfam PF04542 Sigma-70 region 2 55 123 1.0E-17 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 276 3.6E-35 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PRINTS PR00046 Major sigma-70 factor signature 227 239 1.5E-23 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PRINTS PR00046 Major sigma-70 factor signature 263 274 1.5E-23 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PRINTS PR00046 Major sigma-70 factor signature 102 110 1.5E-23 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.5E-23 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PRINTS PR00046 Major sigma-70 factor signature 248 263 1.5E-23 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PANTHER PTHR30603 13 287 1.8E-94 T 22-04-2016 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Gene3D G3DSA:1.10.601.10 12 123 3.4E-48 T 22-04-2016 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 SUPERFAMILY SSF88946 13 124 1.11E-41 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PANTHER PTHR30603:SF0 13 287 1.8E-94 T 22-04-2016 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Gene3D G3DSA:1.10.10.10 220 287 6.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 SUPERFAMILY SSF88659 127 200 9.42E-13 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 SUPERFAMILY SSF88659 189 282 6.92E-23 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Gene3D G3DSA:1.10.10.10 127 174 2.1E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Pfam PF04545 Sigma-70, region 4 223 276 1.1E-16 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Pfam PF00140 Sigma-70 factor, region 1.2 17 48 7.1E-13 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 PIRSF PIRSF000770 15 285 9.0E-38 T 22-04-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 MED134_RS01860 2f279c48dd640b51c1c6c0ee7a1032f6 288 Pfam PF04539 Sigma-70 region 3 134 208 1.9E-12 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 SUPERFAMILY SSF82689 205 304 2.22E-28 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 PANTHER PTHR30347 4 325 1.9E-61 T 22-04-2016 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 Gene3D G3DSA:2.30.30.60 154 201 1.4E-13 T 22-04-2016 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 SUPERFAMILY SSF50182 137 202 1.83E-15 T 22-04-2016 IPR010920 LSM domain MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 Gene3D G3DSA:3.30.70.100 206 291 7.9E-24 T 22-04-2016 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 Pfam PF00924 Mechanosensitive ion channel 94 293 8.2E-48 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS13220 1ec3cc63bc0b2d78e7c112a54a7a4d48 330 SUPERFAMILY SSF82861 54 135 1.44E-8 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 173 6.1E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 Gene3D G3DSA:1.10.10.10 117 178 2.4E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 SUPERFAMILY SSF88659 121 177 6.35E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 SUPERFAMILY SSF88946 8 104 6.28E-19 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 PANTHER PTHR30173 1 176 2.2E-43 T 22-04-2016 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 Pfam PF08281 Sigma-70, region 4 121 171 2.3E-17 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 PANTHER PTHR30173:SF21 1 176 2.2E-43 T 22-04-2016 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 Gene3D G3DSA:1.10.1740.10 8 105 3.7E-22 T 22-04-2016 MED134_RS12435 ba0d91d3e986653f46073e60e2289ba6 189 Pfam PF04542 Sigma-70 region 2 27 91 3.2E-10 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 PANTHER PTHR11532 280 493 3.2E-31 T 22-04-2016 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 PANTHER PTHR11532:SF57 280 493 3.2E-31 T 22-04-2016 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 SUPERFAMILY SSF53300 118 251 7.23E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 Pfam PF07715 TonB-dependent Receptor Plug Domain 384 487 4.3E-11 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 SUPERFAMILY SSF48452 575 648 7.59E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 Gene3D G3DSA:1.25.40.10 560 648 1.0E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 Gene3D G3DSA:2.170.130.10 377 487 4.4E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 Gene3D G3DSA:2.60.40.1120 283 337 1.6E-5 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 SUPERFAMILY SSF49464 282 361 2.75E-10 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08610 080cd25c69e13a5a08a0a1587fee2a79 817 SUPERFAMILY SSF56935 359 500 1.14E-14 T 22-04-2016 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 SUPERFAMILY SSF51161 3 254 1.79E-75 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Gene3D G3DSA:1.20.1180.10 190 255 8.1E-21 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 PANTHER PTHR23416 4 247 1.0E-102 T 22-04-2016 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Gene3D G3DSA:2.160.10.10 3 181 1.9E-49 T 22-04-2016 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 173 254 7.1E-26 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 PANTHER PTHR23416:SF8 4 247 1.0E-102 T 22-04-2016 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 254 1.3E-94 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 4 28 0.0011 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 29 63 8.2E-8 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 102 136 3.7E-12 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS02505 16cc3628a965e6baf0c5365d7d1ed577 260 PIRSF PIRSF000456 1 259 4.9E-97 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 MED134_RS02370 9e0280cec7aeb45d2e64fb4ee1566712 152 Pfam PF07610 Protein of unknown function (DUF1573) 70 113 9.5E-23 T 22-04-2016 IPR011467 Protein of unknown function DUF1573 MED134_RS02370 9e0280cec7aeb45d2e64fb4ee1566712 152 PANTHER PTHR37833:SF1 4 130 7.7E-23 T 22-04-2016 MED134_RS02370 9e0280cec7aeb45d2e64fb4ee1566712 152 PANTHER PTHR37833 4 130 7.7E-23 T 22-04-2016 MED134_RS02370 9e0280cec7aeb45d2e64fb4ee1566712 152 Gene3D G3DSA:2.60.40.360 45 142 5.4E-27 T 22-04-2016 IPR008962 PapD-like MED134_RS00060 afe58a24262cac0c9ed6c5fcfbb03ff0 730 Pfam PF06452 Carbohydrate family 9 binding domain-like 35 208 8.3E-5 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS00060 afe58a24262cac0c9ed6c5fcfbb03ff0 730 SUPERFAMILY SSF49344 26 225 8.63E-33 T 22-04-2016 MED134_RS00060 afe58a24262cac0c9ed6c5fcfbb03ff0 730 Gene3D G3DSA:2.60.40.1190 27 220 1.8E-25 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 203 1.4E-58 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 3 203 8.1E-90 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 PANTHER PTHR30335 3 206 1.4E-108 T 22-04-2016 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 PANTHER PTHR30335:SF1 3 206 1.4E-108 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 PIRSF PIRSF006102 1 217 3.5E-57 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MED134_RS07020 052b021219150bf29bfd39d122762f92 244 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 205 28.832 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MED134_RS07795 ecedeb1c2750ef401be5c43032b56e6f 182 PANTHER PTHR26402 6 109 3.6E-15 T 22-04-2016 MED134_RS07795 ecedeb1c2750ef401be5c43032b56e6f 182 Pfam PF00072 Response regulator receiver domain 8 118 2.5E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07795 ecedeb1c2750ef401be5c43032b56e6f 182 SMART SM00448 6 119 5.8E-8 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07795 ecedeb1c2750ef401be5c43032b56e6f 182 SUPERFAMILY SSF52172 5 142 2.7E-18 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07795 ecedeb1c2750ef401be5c43032b56e6f 182 Gene3D G3DSA:3.40.50.2300 5 152 2.2E-18 T 22-04-2016 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 Gene3D G3DSA:3.40.190.10 4 144 2.3E-41 T 22-04-2016 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 285 4.2E-32 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 SUPERFAMILY SSF53850 4 210 5.96E-64 T 22-04-2016 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 PANTHER PTHR21403:SF0 1 285 4.1E-107 T 22-04-2016 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 185 5.5E-56 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 Gene3D G3DSA:3.30.70.120 214 285 3.1E-31 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 SUPERFAMILY SSF54913 214 285 3.56E-24 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 145 166 - T 22-04-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 4 286 33.128 T 22-04-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 Pfam PF08029 HisG, C-terminal domain 212 283 7.3E-29 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 Pfam PF01634 ATP phosphoribosyltransferase 52 206 4.7E-47 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS02450 500fc32ace11dc7f36a85ff1f6d8fb9e 286 PANTHER PTHR21403 1 285 4.1E-107 T 22-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 Gene3D G3DSA:3.30.420.100 23 118 1.5E-39 T 22-04-2016 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 118 9.9E-40 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 4 118 2.1E-46 T 22-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 PANTHER PTHR12899 2 118 5.1E-38 T 22-04-2016 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 SUPERFAMILY SSF53137 5 116 2.05E-47 T 22-04-2016 MED134_RS12315 b4ac2665a62002b026d0d308e2abab98 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 4 118 27.867 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 PANTHER PTHR30204:SF15 3 109 4.9E-23 T 22-04-2016 MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 SUPERFAMILY SSF46955 11 103 2.52E-17 T 22-04-2016 IPR009061 Putative DNA-binding domain MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 PANTHER PTHR30204 3 109 4.9E-23 T 22-04-2016 MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 SMART SM00422 11 81 6.9E-10 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 Gene3D G3DSA:1.10.1660.10 11 104 8.8E-17 T 22-04-2016 MED134_RS11445 339c2702478bf62edee2eb26e122e7b6 109 Pfam PF13411 MerR HTH family regulatory protein 11 79 5.3E-22 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MED134_RS14325 3041204750fbe2048586be3b9d56db40 361 Gene3D G3DSA:3.60.10.10 101 323 2.8E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS14325 3041204750fbe2048586be3b9d56db40 361 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 109 316 1.9E-27 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS14325 3041204750fbe2048586be3b9d56db40 361 SUPERFAMILY SSF56219 105 323 1.07E-31 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 SUPERFAMILY SSF51735 1 153 1.5E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 Gene3D G3DSA:3.40.50.720 1 138 4.2E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 SUPERFAMILY SSF55347 125 311 1.09E-68 T 22-04-2016 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 SMART SM00859 2 117 3.5E-34 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 326 1.3E-128 T 22-04-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 324 33.095 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 PANTHER PTHR10174 46 324 2.0E-67 T 22-04-2016 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 PANTHER PTHR10174:SF2 46 324 2.0E-67 T 22-04-2016 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 310 1.1E-42 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 114 4.2E-29 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 PIRSF PIRSF000148 1 329 6.5E-119 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS09855 486a664fedbd5229891d4fc184590ccb 329 Gene3D G3DSA:3.30.360.10 139 306 3.8E-70 T 22-04-2016 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PANTHER PTHR11751 18 79 3.5E-22 T 22-04-2016 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PANTHER PTHR11751 95 118 3.5E-22 T 22-04-2016 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 SMART SM00345 18 77 7.8E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 Gene3D G3DSA:1.10.10.10 12 79 2.9E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 SUPERFAMILY SSF48008 101 229 6.8E-26 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.7E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.7E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 Gene3D G3DSA:1.20.120.530 102 225 1.1E-25 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PANTHER PTHR11751:SF382 18 79 3.5E-22 T 22-04-2016 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 PANTHER PTHR11751:SF382 95 118 3.5E-22 T 22-04-2016 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 3.3E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 SUPERFAMILY SSF46785 15 81 5.07E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 SMART SM00895 102 225 3.6E-19 T 22-04-2016 IPR011711 GntR, C-terminal MED134_RS10475 35936210a8347eb729540dd6afc68d5b 233 Pfam PF07729 FCD domain 103 224 8.3E-23 T 22-04-2016 IPR011711 GntR, C-terminal MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 22-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 1.9E-27 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 SUPERFAMILY SSF57716 2 89 2.28E-32 T 22-04-2016 MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 24.602 T 22-04-2016 IPR023036 Ribosomal protein S14, bacterial/plastid MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 Gene3D G3DSA:4.10.830.10 36 89 7.9E-30 T 22-04-2016 MED134_RS12300 f11cb9635e6780991fadae454d2a94cb 89 PANTHER PTHR19836 1 89 4.6E-49 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 PANTHER PTHR30559 1 355 2.8E-231 T 22-04-2016 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 PANTHER PTHR30559:SF0 1 355 2.8E-231 T 22-04-2016 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 SUPERFAMILY SSF51569 4 353 2.34E-127 T 22-04-2016 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 168 179 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 Gene3D G3DSA:3.20.20.70 8 353 2.5E-124 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 Pfam PF01116 Fructose-bisphosphate aldolase class-II 14 352 3.3E-89 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 354 3.0E-174 T 22-04-2016 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 12 354 8.3E-109 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MED134_RS05510 9f7c9c8d295be914b7996b5d7334070f 355 PIRSF PIRSF001359 10 355 4.1E-87 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 382 398 2.8E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 236 2.8E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PRINTS PR00723 Subtilisin serine protease family (S8) signature 182 201 2.8E-16 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795 169 395 1.6E-64 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795 53 142 1.6E-64 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795 1 28 1.6E-64 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 Gene3D G3DSA:3.40.50.200 129 397 1.1E-62 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 187 198 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795:SF389 169 395 1.6E-64 T 22-04-2016 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795:SF389 53 142 1.6E-64 T 22-04-2016 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 PANTHER PTHR10795:SF389 1 28 1.6E-64 T 22-04-2016 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 383 393 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 227 237 - T 22-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 Pfam PF05922 Peptidase inhibitor I9 60 140 5.9E-8 T 22-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 Pfam PF00082 Subtilase family 189 395 2.0E-30 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 Gene3D G3DSA:3.30.70.80 54 128 2.4E-13 T 22-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 SUPERFAMILY SSF54897 57 139 1.87E-9 T 22-04-2016 IPR009020 Proteinase inhibitor, propeptide MED134_RS08855 c7eda55acaa632c5266b2fe35b58ccd8 420 SUPERFAMILY SSF52743 168 396 1.83E-52 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 Pfam PF00117 Glutamine amidotransferase class-I 186 363 1.7E-43 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 9 137 1.3E-45 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 SUPERFAMILY SSF52021 8 155 3.66E-46 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PANTHER PTHR11405 7 366 3.6E-168 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 9 366 2.7E-138 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 Gene3D G3DSA:3.40.50.880 157 367 1.4E-66 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00097 Anthranilate synthase component II signature 340 353 2.0E-6 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00097 Anthranilate synthase component II signature 225 234 2.0E-6 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00097 Anthranilate synthase component II signature 253 264 2.0E-6 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 7 369 43.612 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 SMART SM01097 7 138 1.9E-65 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 Gene3D G3DSA:3.50.30.20 8 153 4.9E-50 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 269 4.3E-35 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 222 236 4.3E-35 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 287 4.3E-35 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 306 4.3E-35 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 183 197 4.3E-35 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 225 234 1.2E-11 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 340 353 1.2E-11 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 253 264 1.2E-11 T 22-04-2016 MED134_RS12375 beb3e70d2e496111e4a066e6c9735581 370 SUPERFAMILY SSF52317 154 367 8.88E-56 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12915 fe4cd25bfa6d823ce92c33381969eccd 167 Gene3D G3DSA:3.40.50.2020 7 147 1.6E-24 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS12915 fe4cd25bfa6d823ce92c33381969eccd 167 SUPERFAMILY SSF53271 8 162 4.33E-26 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS12915 fe4cd25bfa6d823ce92c33381969eccd 167 Pfam PF00156 Phosphoribosyl transferase domain 6 151 2.4E-22 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 MED134_RS12915 fe4cd25bfa6d823ce92c33381969eccd 167 PANTHER PTHR11608 2 162 1.4E-19 T 22-04-2016 MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 Gene3D G3DSA:3.40.50.1000 95 225 9.4E-36 T 22-04-2016 IPR023214 HAD-like domain MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 201 4.2E-25 T 22-04-2016 IPR023214 HAD-like domain MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 SUPERFAMILY SSF56784 4 224 5.8E-46 T 22-04-2016 IPR023214 HAD-like domain MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 PANTHER PTHR12725 1 220 7.3E-35 T 22-04-2016 MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 197 1.0E-10 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 6 225 4.6E-60 T 22-04-2016 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 MED134_RS12150 fd58aaaacdc5dfb41e1115d2acc5d2cc 227 Gene3D G3DSA:1.10.150.240 17 94 2.9E-15 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 202 257 - T 22-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 488 720 5.2E-99 T 22-04-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 PANTHER PTHR10422 1 466 1.8E-300 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 PANTHER PTHR10422 539 644 1.8E-300 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 SUPERFAMILY SSF81442 8 480 1.06E-119 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 PANTHER PTHR10422:SF21 1 466 1.8E-300 T 22-04-2016 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 PANTHER PTHR10422:SF21 539 644 1.8E-300 T 22-04-2016 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 Gene3D G3DSA:1.20.210.10 9 487 3.5E-70 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 Gene3D G3DSA:1.10.760.10 500 645 8.4E-26 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 8 471 4.2E-198 T 22-04-2016 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 11 441 1.9E-115 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 489 725 2.4E-76 T 22-04-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MED134_RS04590 5e201c988ffefdd69cb53becc0abdadb 734 SUPERFAMILY SSF46626 532 658 6.1E-22 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04115 987c43f767ea6c28a676ced299e78472 147 SUPERFAMILY SSF55729 1 144 1.13E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS04115 987c43f767ea6c28a676ced299e78472 147 PANTHER PTHR23091:SF256 1 144 1.1E-27 T 22-04-2016 MED134_RS04115 987c43f767ea6c28a676ced299e78472 147 Gene3D G3DSA:3.40.630.30 1 144 5.3E-34 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS04115 987c43f767ea6c28a676ced299e78472 147 Pfam PF00583 Acetyltransferase (GNAT) family 59 136 4.9E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS04115 987c43f767ea6c28a676ced299e78472 147 PANTHER PTHR23091 1 144 1.1E-27 T 22-04-2016 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 SUPERFAMILY SSF46548 119 242 1.92E-19 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 Gene3D G3DSA:1.10.1060.10 111 242 9.9E-19 T 22-04-2016 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 PANTHER PTHR11921:SF13 3 247 1.2E-113 T 22-04-2016 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 PANTHER PTHR11921 3 247 1.2E-113 T 22-04-2016 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 SUPERFAMILY SSF54292 1 116 6.86E-21 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 Gene3D G3DSA:3.10.20.30 1 110 1.2E-28 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 120 7.3E-23 T 22-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 MED134_RS11000 f46659ee9ed483dab51e8df3cb551cb0 248 Pfam PF13183 4Fe-4S dicluster domain 158 229 4.5E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS01225 f7ed5b285753bc7db128afe98ad35c42 288 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 279 3.4E-26 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MED134_RS01225 f7ed5b285753bc7db128afe98ad35c42 288 PANTHER PTHR30606 1 279 1.6E-40 T 22-04-2016 MED134_RS01225 f7ed5b285753bc7db128afe98ad35c42 288 PANTHER PTHR30606:SF2 1 279 1.6E-40 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:3.20.20.70 510 820 2.1E-129 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 PIRSF PIRSF001594 1 1150 0.0 T 22-04-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|UniPathway: UPA00138 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 324 1.8E-72 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF89000 834 1015 9.02E-52 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 112 1.0E-44 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF51230 1074 1150 1.05E-20 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:3.30.470.20 205 456 2.4E-95 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:3.10.600.10 993 1069 1.1E-30 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF02436 Conserved carboxylase domain 829 1033 1.5E-70 T 22-04-2016 IPR003379 Carboxylase, conserved domain MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF00364 Biotin-requiring enzyme 1083 1149 5.3E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF51246 339 457 4.97E-37 T 22-04-2016 IPR011054 Rudiment single hybrid motif MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SMART SM00878 344 451 2.1E-48 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF00682 HMGL-like 532 806 9.7E-29 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:2.40.50.100 1075 1150 2.1E-24 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF51569 525 837 4.76E-80 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:1.10.10.60 952 992 3.8E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF52440 2 115 4.89E-45 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 PANTHER PTHR18866 2 1150 0.0 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:3.30.1490.20 131 204 4.8E-27 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1106 1123 - T 22-04-2016 IPR001882 Biotin-binding site MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 SUPERFAMILY SSF56059 85 358 1.08E-66 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 PANTHER PTHR18866:SF103 2 1150 0.0 T 22-04-2016 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Gene3D G3DSA:3.40.50.20 3 130 5.1E-53 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 Pfam PF02785 Biotin carboxylase C-terminal domain 344 451 9.6E-33 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 5 1150 0.0 T 22-04-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|UniPathway: UPA00138 MED134_RS01135 c016e31d6756faee94b05ef9ed0f4fbe 1150 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Pfam PF07715 TonB-dependent Receptor Plug Domain 117 215 3.8E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Gene3D G3DSA:2.60.40.1120 21 104 1.7E-5 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 PANTHER PTHR32552 128 739 1.3E-88 T 22-04-2016 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Pfam PF00593 TonB dependent receptor 499 706 5.5E-10 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 SUPERFAMILY SSF56935 91 739 7.33E-75 T 22-04-2016 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 SUPERFAMILY SSF49464 19 100 3.14E-10 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Gene3D G3DSA:2.170.130.10 117 220 1.4E-17 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Pfam PF13715 CarboxypepD_reg-like domain 21 103 4.3E-11 T 22-04-2016 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 Gene3D G3DSA:2.40.170.20 221 733 1.7E-50 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS11365 f3b57cfc7f924e76ef1066be0d8969a3 739 PANTHER PTHR32552:SF36 128 739 1.3E-88 T 22-04-2016 MED134_RS05060 e511117beb643d3bd96b4bc81d5fb89b 312 PANTHER PTHR30589 1 192 1.2E-40 T 22-04-2016 MED134_RS05060 e511117beb643d3bd96b4bc81d5fb89b 312 PANTHER PTHR30589 210 310 1.2E-40 T 22-04-2016 MED134_RS05060 e511117beb643d3bd96b4bc81d5fb89b 312 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 306 14.472 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 MED134_RS05060 e511117beb643d3bd96b4bc81d5fb89b 312 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 14 307 7.8E-41 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 MED134_RS05060 e511117beb643d3bd96b4bc81d5fb89b 312 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 15 300 5.0E-56 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 MED134_RS06235 235535945e4d5ba1735bcfcf2628e84a 281 PANTHER PTHR34138:SF1 1 281 1.4E-31 T 22-04-2016 MED134_RS06235 235535945e4d5ba1735bcfcf2628e84a 281 PANTHER PTHR34138 1 281 1.4E-31 T 22-04-2016 MED134_RS06235 235535945e4d5ba1735bcfcf2628e84a 281 PIRSF PIRSF038471 6 278 5.0E-33 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 MED134_RS06235 235535945e4d5ba1735bcfcf2628e84a 281 Pfam PF04085 rod shape-determining protein MreC 116 263 3.1E-32 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 14 239 14.766 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 17 226 2.9E-62 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 45 190 9.0E-53 T 22-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 SUPERFAMILY SSF55120 16 229 4.8E-70 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 PANTHER PTHR13767 11 222 3.9E-104 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 230 7.5E-8 T 22-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal MED134_RS09605 442a52bf28323b7c4d0c4a6090df9b34 241 PANTHER PTHR13767:SF9 11 222 3.9E-104 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Gene3D G3DSA:1.25.40.10 1041 1129 5.1E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 SUPERFAMILY SSF49464 762 840 5.62E-9 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 SUPERFAMILY SSF56935 878 1028 2.11E-13 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Gene3D G3DSA:2.60.40.1120 284 368 9.3E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Gene3D G3DSA:2.60.40.1120 25 85 9.6E-7 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Gene3D G3DSA:2.60.40.1120 762 811 2.0E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 PANTHER PTHR11532 437 973 7.4E-18 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Pfam PF07715 TonB-dependent Receptor Plug Domain 879 967 1.6E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Gene3D G3DSA:2.170.130.10 878 968 3.6E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 SUPERFAMILY SSF49464 25 88 2.09E-6 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 SUPERFAMILY SSF49464 524 602 6.8E-8 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 SUPERFAMILY SSF49464 282 361 6.02E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 PANTHER PTHR11532:SF57 437 973 7.4E-18 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Pfam PF13715 CarboxypepD_reg-like domain 525 603 3.9E-8 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Pfam PF13715 CarboxypepD_reg-like domain 763 841 2.7E-8 T 22-04-2016 MED134_RS08605 c4c590f48fbaba3eb6024d64ea023281 1297 Pfam PF13715 CarboxypepD_reg-like domain 284 362 4.6E-11 T 22-04-2016 MED134_RS13145 6be9d8073c171cffeb058980c4c22d8e 255 SUPERFAMILY SSF116726 142 223 1.03E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS13145 6be9d8073c171cffeb058980c4c22d8e 255 Gene3D G3DSA:3.30.70.1450 152 223 2.1E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS13145 6be9d8073c171cffeb058980c4c22d8e 255 Pfam PF02080 TrkA-C domain 156 224 4.1E-12 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.1E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 1.1E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 1.1E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.1E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 PANTHER PTHR10992 13 251 6.0E-43 T 22-04-2016 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 SUPERFAMILY SSF53474 9 251 1.49E-48 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 Pfam PF12146 Serine aminopeptidase, S33 22 237 1.2E-12 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS12485 5fbf9c1f36b0f847e2cba8bc820dfd17 254 Gene3D G3DSA:3.40.50.1820 11 251 3.5E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08915 263d60928c82a741c23217ce94208116 598 PANTHER PTHR30562:SF1 6 594 8.6E-206 T 22-04-2016 MED134_RS08915 263d60928c82a741c23217ce94208116 598 Gene3D G3DSA:3.40.1440.10 16 95 1.2E-11 T 22-04-2016 IPR027299 GIY-YIG domain MED134_RS08915 263d60928c82a741c23217ce94208116 598 Hamap MF_00203 UvrABC system protein C [uvrC]. 3 593 25.221 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MED134_RS08915 263d60928c82a741c23217ce94208116 598 Gene3D G3DSA:1.10.150.20 545 595 1.5E-13 T 22-04-2016 MED134_RS08915 263d60928c82a741c23217ce94208116 598 PANTHER PTHR30562 6 594 8.6E-206 T 22-04-2016 MED134_RS08915 263d60928c82a741c23217ce94208116 598 Gene3D G3DSA:4.10.860.10 187 240 9.6E-9 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS08915 263d60928c82a741c23217ce94208116 598 SUPERFAMILY SSF47781 491 595 2.51E-17 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS08915 263d60928c82a741c23217ce94208116 598 SUPERFAMILY SSF46600 193 244 6.28E-8 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS08915 263d60928c82a741c23217ce94208116 598 Pfam PF01541 GIY-YIG catalytic domain 18 92 2.2E-10 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS08915 263d60928c82a741c23217ce94208116 598 Pfam PF14520 Helix-hairpin-helix domain 545 587 9.4E-6 T 22-04-2016 MED134_RS08915 263d60928c82a741c23217ce94208116 598 SUPERFAMILY SSF82771 16 99 6.67E-23 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS08915 263d60928c82a741c23217ce94208116 598 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 382 530 3.8E-49 T 22-04-2016 IPR001162 UvrC family homology region MED134_RS08915 263d60928c82a741c23217ce94208116 598 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 576 1.1E-154 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MED134_RS08915 263d60928c82a741c23217ce94208116 598 SMART SM00465 16 97 3.9E-20 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS08205 870499d42680c1e154afebd9bafec55c 237 PANTHER PTHR10204:SF48 10 225 3.5E-28 T 22-04-2016 MED134_RS08205 870499d42680c1e154afebd9bafec55c 237 SUPERFAMILY SSF52218 11 209 1.07E-29 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS08205 870499d42680c1e154afebd9bafec55c 237 Pfam PF03358 NADPH-dependent FMN reductase 11 162 1.7E-14 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MED134_RS08205 870499d42680c1e154afebd9bafec55c 237 Gene3D G3DSA:3.40.50.360 11 168 1.8E-18 T 22-04-2016 IPR029039 Flavoprotein-like domain MED134_RS08205 870499d42680c1e154afebd9bafec55c 237 PANTHER PTHR10204 10 225 3.5E-28 T 22-04-2016 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 5 256 7.7E-84 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 5 446 1.6E-130 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 PANTHER PTHR37839:SF1 2 448 4.2E-136 T 22-04-2016 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 PANTHER PTHR37839 2 448 4.2E-136 T 22-04-2016 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 Pfam PF11973 NQRA C-terminal domain 261 310 1.1E-16 T 22-04-2016 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 MED134_RS07040 9e3eab71e54b214065a2ecfb2a20d644 448 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 4 447 40.713 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 PANTHER PTHR23151:SF8 8 424 7.6E-130 T 22-04-2016 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 SUPERFAMILY SSF52777 197 425 9.34E-77 T 22-04-2016 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Gene3D G3DSA:4.10.320.10 121 169 7.0E-11 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Pfam PF00364 Biotin-requiring enzyme 6 76 2.2E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 PANTHER PTHR23151 8 424 7.6E-130 T 22-04-2016 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Gene3D G3DSA:3.30.559.10 195 426 2.3E-79 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 SUPERFAMILY SSF47005 121 168 4.84E-7 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 426 1.4E-74 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 SUPERFAMILY SSF51230 3 96 7.59E-24 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Pfam PF02817 e3 binding domain 125 162 2.4E-6 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11560 cfe0b33ae8f44493447029ad5d53d729 431 Gene3D G3DSA:2.40.50.100 2 97 2.0E-26 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 SUPERFAMILY SSF141072 200 305 9.42E-7 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 585 653 7.4E-13 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 PANTHER PTHR33607 330 425 2.1E-30 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 PANTHER PTHR33607 446 562 2.1E-30 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 SUPERFAMILY SSF54060 343 554 7.65E-29 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 PANTHER PTHR33607:SF2 330 425 2.1E-30 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 PANTHER PTHR33607:SF2 446 562 2.1E-30 T 22-04-2016 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 Pfam PF04231 Endonuclease I 480 554 4.0E-15 T 22-04-2016 IPR007346 Endonuclease I GO:0004518 MED134_RS14320 68dac46d213e20a99c6edf8b96875168 653 Pfam PF04231 Endonuclease I 345 473 2.0E-9 T 22-04-2016 IPR007346 Endonuclease I GO:0004518 MED134_RS04675 cf8bc4c2e536b185ca7e603745f2fc8e 103 SUPERFAMILY SSF69754 1 93 6.67E-20 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS04675 cf8bc4c2e536b185ca7e603745f2fc8e 103 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 1.6E-14 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS04675 cf8bc4c2e536b185ca7e603745f2fc8e 103 Gene3D G3DSA:3.30.160.100 1 95 1.5E-18 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS04675 cf8bc4c2e536b185ca7e603745f2fc8e 103 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.3E-11 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS10385 b8ddc0c38f714352c4f5ebb1f297b1ee 104 PANTHER PTHR37811 2 104 2.8E-34 T 22-04-2016 MED134_RS10385 b8ddc0c38f714352c4f5ebb1f297b1ee 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 23 78 3.8E-6 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain MED134_RS10385 b8ddc0c38f714352c4f5ebb1f297b1ee 104 Gene3D G3DSA:3.30.70.900 18 101 1.5E-15 T 22-04-2016 MED134_RS10385 b8ddc0c38f714352c4f5ebb1f297b1ee 104 SUPERFAMILY SSF54909 2 102 2.23E-31 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS10385 b8ddc0c38f714352c4f5ebb1f297b1ee 104 PANTHER PTHR37811:SF2 2 104 2.8E-34 T 22-04-2016 MED134_RS05825 6da4785a9027db637981e35eaac894b2 128 Pfam PF07610 Protein of unknown function (DUF1573) 48 91 1.1E-18 T 22-04-2016 IPR011467 Protein of unknown function DUF1573 MED134_RS05825 6da4785a9027db637981e35eaac894b2 128 PANTHER PTHR37833 1 126 8.0E-23 T 22-04-2016 MED134_RS05825 6da4785a9027db637981e35eaac894b2 128 Gene3D G3DSA:2.60.40.360 25 122 2.1E-22 T 22-04-2016 IPR008962 PapD-like MED134_RS05825 6da4785a9027db637981e35eaac894b2 128 PANTHER PTHR37833:SF1 1 126 8.0E-23 T 22-04-2016 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 72 1.0E-18 T 22-04-2016 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.9E-47 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 Gene3D G3DSA:1.10.1900.20 55 114 4.6E-30 T 22-04-2016 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 114 25.32 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 PANTHER PTHR10986 2 114 1.7E-54 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 Pfam PF00453 Ribosomal protein L20 3 109 1.3E-46 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 SUPERFAMILY SSF74731 3 114 6.67E-46 T 22-04-2016 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 PANTHER PTHR10986:SF12 2 114 1.7E-54 T 22-04-2016 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.4E-36 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.4E-36 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS06320 6a5cbd5e826d399d91dedfd1b2c1a285 114 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.4E-36 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 MED134_RS13410 802031e838c973dc25c27b81e1c9a910 364 Pfam PF00534 Glycosyl transferases group 1 205 334 2.6E-15 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS13410 802031e838c973dc25c27b81e1c9a910 364 SUPERFAMILY SSF53756 4 361 6.8E-24 T 22-04-2016 MED134_RS13410 802031e838c973dc25c27b81e1c9a910 364 PANTHER PTHR12526 206 363 3.7E-12 T 22-04-2016 MED134_RS13410 802031e838c973dc25c27b81e1c9a910 364 Gene3D G3DSA:3.40.50.2000 206 329 8.5E-8 T 22-04-2016 MED134_RS13410 802031e838c973dc25c27b81e1c9a910 364 Pfam PF13477 Glycosyl transferase 4-like 2 135 2.5E-6 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS03800 2931935405f33d182e97854c6aa1a9eb 465 SUPERFAMILY SSF56925 317 447 2.38E-8 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS03800 2931935405f33d182e97854c6aa1a9eb 465 Gene3D G3DSA:2.40.160.20 315 421 1.6E-6 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS03800 2931935405f33d182e97854c6aa1a9eb 465 Pfam PF03783 Curli production assembly/transport component CsgG 52 262 8.1E-65 T 22-04-2016 IPR005534 Curli production assembly/transport component CsgG GO:0030288 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 Gene3D G3DSA:1.10.1040.10 187 330 6.7E-45 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 SUPERFAMILY SSF51735 1 183 8.2E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PIRSF PIRSF000114 1 332 9.5E-89 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 325 2.5E-45 T 22-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 SUPERFAMILY SSF48179 182 330 3.4E-39 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PANTHER PTHR11728:SF1 1 331 6.2E-84 T 22-04-2016 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 163 2.6E-32 T 22-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 Gene3D G3DSA:3.40.50.720 1 186 2.5E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PANTHER PTHR11728 1 331 6.2E-84 T 22-04-2016 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS09875 4af9011cf7e84cf847de8ee64a6231d5 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 5.0E-33 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 812 876 2.7E-14 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 877 14.073 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 SUPERFAMILY SSF50677 190 340 9.03E-53 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 SUPERFAMILY SSF46589 812 876 2.14E-14 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Gene3D G3DSA:1.10.730.10 527 750 7.2E-53 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Gene3D G3DSA:1.10.287.380 805 876 4.3E-6 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 574 2.1E-179 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PRINTS PR00986 Valyl-tRNA synthetase signature 345 358 4.1E-28 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PRINTS PR00986 Valyl-tRNA synthetase signature 230 247 4.1E-28 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PRINTS PR00986 Valyl-tRNA synthetase signature 454 475 4.1E-28 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 4.1E-28 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PRINTS PR00986 Valyl-tRNA synthetase signature 487 505 4.1E-28 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 SUPERFAMILY SSF47323 616 825 1.68E-36 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PANTHER PTHR11946 1 789 0.0 T 22-04-2016 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PANTHER PTHR11946 808 875 0.0 T 22-04-2016 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PANTHER PTHR11946:SF5 1 789 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 PANTHER PTHR11946:SF5 808 875 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Gene3D G3DSA:3.40.50.620 345 526 6.4E-100 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Gene3D G3DSA:3.40.50.620 30 162 6.4E-100 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 859 2.8E-268 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Gene3D G3DSA:3.90.740.10 163 333 6.2E-51 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 SUPERFAMILY SSF52374 340 582 4.33E-124 T 22-04-2016 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 SUPERFAMILY SSF52374 3 192 4.33E-124 T 22-04-2016 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05830 1a886cb64e6d343f87435910470fa3dc 877 Pfam PF08264 Anticodon-binding domain of tRNA 617 758 2.3E-29 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 Pfam PF00884 Sulfatase 36 338 2.0E-56 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 ProSitePatterns PS00523 Sulfatases signature 1. 83 95 - T 22-04-2016 IPR024607 Sulfatase, conserved site MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 Gene3D G3DSA:3.40.720.10 35 374 8.7E-78 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 Gene3D G3DSA:3.30.1120.10 375 428 3.2E-8 T 22-04-2016 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 SUPERFAMILY SSF53649 35 414 9.01E-91 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 PANTHER PTHR10342 2 432 3.7E-86 T 22-04-2016 MED134_RS14455 b87528737bc44f97bf5972c132ec26ac 432 PANTHER PTHR10342:SF199 2 432 3.7E-86 T 22-04-2016 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 2.1E-141 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 SUPERFAMILY SSF81271 281 360 9.59E-36 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PANTHER PTHR23305 1 364 2.3E-185 T 22-04-2016 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 SUPERFAMILY SSF52540 1 302 1.32E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PIRSF PIRSF006641 1 364 1.2E-152 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Gene3D G3DSA:3.10.20.30 262 364 8.8E-47 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Pfam PF06071 Protein of unknown function (DUF933) 281 363 3.8E-39 T 22-04-2016 IPR013029 Domain of unknown function DUF933 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PANTHER PTHR23305:SF12 1 364 2.3E-185 T 22-04-2016 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Gene3D G3DSA:3.40.50.300 200 261 2.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Gene3D G3DSA:3.40.50.300 2 131 2.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 364 41.438 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Gene3D G3DSA:1.10.150.300 132 199 3.1E-21 T 22-04-2016 IPR023192 TGS-like domain MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.1E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 103 4.1E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.1E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 83 4.1E-36 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS00305 e6870f271fec3505825bf9d3861f6636 364 Pfam PF01926 50S ribosome-binding GTPase 3 116 3.3E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 Gene3D G3DSA:1.10.760.10 190 287 2.0E-29 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 Gene3D G3DSA:1.10.760.10 132 154 2.0E-29 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 PANTHER PTHR33751:SF1 97 287 2.2E-47 T 22-04-2016 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 SUPERFAMILY SSF46626 128 280 9.03E-26 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 PANTHER PTHR33751 97 287 2.2E-47 T 22-04-2016 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 195 270 3.7E-11 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS04580 2adf7f8939fd7c402d787f2984c78add 316 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 111 153 1.7E-20 T 22-04-2016 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal UniPathway: UPA00705 MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 PANTHER PTHR22572:SF105 2 266 1.3E-141 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 283 1.2E-131 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 SUPERFAMILY SSF53448 1 282 2.93E-80 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 Pfam PF00483 Nucleotidyl transferase 2 236 1.1E-64 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 Gene3D G3DSA:3.90.550.10 1 259 1.8E-63 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS01345 1f83d450fff7169b1fe397f44324a85a 284 PANTHER PTHR22572 2 266 1.3E-141 T 22-04-2016 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 311 327 8.1E-17 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 409 424 8.1E-17 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 284 302 8.1E-17 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 367 384 8.1E-17 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 248 261 8.1E-17 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 SMART SM00846 128 290 1.6E-45 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 Gene3D G3DSA:3.40.50.720 129 298 2.9E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PANTHER PTHR10836:SF35 116 479 6.3E-193 T 22-04-2016 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 295 454 6.0E-45 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 SUPERFAMILY SSF51735 129 305 5.12E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 129 290 7.1E-38 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 PANTHER PTHR10836 116 479 6.3E-193 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 Gene3D G3DSA:3.30.360.10 299 456 5.6E-53 T 22-04-2016 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 288 295 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS04005 276b2801e337d4ecbbd9b47ddb27590b 480 SUPERFAMILY SSF55347 290 455 8.46E-52 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 SUPERFAMILY SSF143456 5 182 1.31E-49 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 PANTHER PTHR30327:SF1 4 186 3.3E-37 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 Gene3D G3DSA:3.40.1740.10 4 44 1.2E-21 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 Gene3D G3DSA:3.40.1740.10 126 173 1.2E-21 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 Pfam PF02622 Uncharacterized ACR, COG1678 18 170 1.5E-38 T 22-04-2016 IPR003774 Protein of unknown function UPF0301 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 Gene3D G3DSA:3.30.70.1300 47 125 9.4E-10 T 22-04-2016 MED134_RS04540 93862f16b26b669a80cdaf0ab79f9bac 186 PANTHER PTHR30327 4 186 3.3E-37 T 22-04-2016 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 400 486 3.7E-25 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PANTHER PTHR10724:SF6 55 557 4.7E-196 T 22-04-2016 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 323 399 7.2E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 68 159 1.92E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 409 481 2.3E-21 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 237 307 1.4E-23 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 150 218 1.5E-8 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 69 134 1.3E-8 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 496 563 2.1E-7 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SMART SM00316 322 394 2.1E-22 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 135 221 2.57E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 236 307 3.4E-19 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 321 394 8.7E-17 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 71 134 1.6E-5 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 150 218 6.1E-8 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 408 481 3.8E-14 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Pfam PF00575 S1 RNA binding domain 495 561 4.7E-7 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 148 219 2.6E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 487 561 1.1E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PANTHER PTHR10724 55 557 4.7E-196 T 22-04-2016 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 72 147 2.3E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 Gene3D G3DSA:2.40.50.140 239 322 4.4E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 236 324 1.1E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 476 578 2.16E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 302 400 2.86E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 89 103 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 155 171 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 377 395 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 337 356 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 202 222 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 71 89 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 173 190 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 131 150 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 PRINTS PR00681 Ribosomal protein S1 signature 259 280 6.4E-64 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS04360 6f589e17e2ae1f27bd49cc3b36e05096 610 SUPERFAMILY SSF50249 389 505 3.88E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 SUPERFAMILY SSF53244 305 445 1.56E-37 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 SUPERFAMILY SSF51984 8 96 6.15E-18 T 22-04-2016 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Pfam PF01225 Mur ligase family, catalytic domain 10 112 8.6E-14 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Gene3D G3DSA:3.90.190.20 308 439 4.2E-41 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 PANTHER PTHR23135 2 440 4.7E-132 T 22-04-2016 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 392 6.8E-19 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 7 448 30.872 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 SUPERFAMILY SSF53623 101 303 4.06E-54 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Gene3D G3DSA:3.40.1190.10 101 307 1.1E-51 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 PANTHER PTHR23135:SF5 2 440 4.7E-132 T 22-04-2016 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Pfam PF08245 Mur ligase middle domain 118 285 1.7E-15 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 Gene3D G3DSA:3.40.50.720 9 96 9.8E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12535 a4651a072e3cb0dca3da95b554faa33f 450 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 9 436 2.4E-104 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS07415 4058d12041e4ad99b2868e6662b6d5f7 237 PANTHER PTHR34300 23 224 2.0E-42 T 22-04-2016 MED134_RS07415 4058d12041e4ad99b2868e6662b6d5f7 237 PANTHER PTHR34300:SF2 23 224 2.0E-42 T 22-04-2016 MED134_RS07415 4058d12041e4ad99b2868e6662b6d5f7 237 Pfam PF02592 Putative vitamin uptake transporter 56 216 3.0E-45 T 22-04-2016 IPR003744 Protein of unknown function DUF165 MED134_RS07415 4058d12041e4ad99b2868e6662b6d5f7 237 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 223 1.1E-40 T 22-04-2016 IPR003744 Protein of unknown function DUF165 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 6.5E-57 T 22-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 PANTHER PTHR32125:SF1 1 225 2.7E-98 T 22-04-2016 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 225 95.005 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 SUPERFAMILY SSF75217 1 224 1.44E-90 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 Gene3D G3DSA:3.40.1280.10 1 159 4.1E-64 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 224 5.7E-87 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 PANTHER PTHR32125 1 225 2.7E-98 T 22-04-2016 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 Gene3D G3DSA:1.10.1270.20 160 224 3.1E-26 T 22-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MED134_RS04120 776f75c9e5e97c18e4e8fd3bcb99812f 225 PIRSF PIRSF000386 1 225 1.7E-94 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MED134_RS03235 9d4f85094c179356acc608965589180b 392 PANTHER PTHR30535 100 387 1.3E-62 T 22-04-2016 MED134_RS03235 9d4f85094c179356acc608965589180b 392 SUPERFAMILY SSF53807 95 378 3.61E-40 T 22-04-2016 MED134_RS03235 9d4f85094c179356acc608965589180b 392 Gene3D G3DSA:3.40.50.1980 222 380 6.1E-17 T 22-04-2016 MED134_RS03235 9d4f85094c179356acc608965589180b 392 PANTHER PTHR30535:SF11 100 387 1.3E-62 T 22-04-2016 MED134_RS03235 9d4f85094c179356acc608965589180b 392 Gene3D G3DSA:3.40.50.1980 95 218 2.2E-10 T 22-04-2016 MED134_RS03235 9d4f85094c179356acc608965589180b 392 Pfam PF01497 Periplasmic binding protein 108 344 2.1E-22 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Gene3D G3DSA:1.10.287.130 507 578 1.1E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Gene3D G3DSA:3.30.565.10 586 734 4.5E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PANTHER PTHR24423:SF518 49 735 5.1E-106 T 22-04-2016 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SUPERFAMILY SSF55785 3 116 1.67E-22 T 22-04-2016 IPR000014 PAS domain MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SMART SM00065 142 315 1.7E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SUPERFAMILY SSF55781 294 495 2.16E-45 T 22-04-2016 IPR029016 GAF domain-like MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SUPERFAMILY SSF55874 572 734 9.3E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Gene3D G3DSA:3.30.450.40 127 300 1.9E-11 T 22-04-2016 IPR029016 GAF domain-like MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SUPERFAMILY SSF55781 127 305 1.04E-51 T 22-04-2016 IPR029016 GAF domain-like MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Pfam PF00512 His Kinase A (phospho-acceptor) domain 517 579 2.5E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PANTHER PTHR24423 49 735 5.1E-106 T 22-04-2016 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 734 6.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Pfam PF08446 PAS fold 17 116 7.0E-9 T 22-04-2016 IPR013654 PAS fold-2 GO:0006355 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Pfam PF01590 GAF domain 144 306 3.7E-21 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SMART SM00388 515 583 1.4E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SMART SM00387 625 735 1.4E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PRINTS PR01033 Phytochrome signature 157 176 6.2E-13 T 22-04-2016 IPR001294 Phytochrome GO:0006355|GO:0009584 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PRINTS PR01033 Phytochrome signature 243 264 6.2E-13 T 22-04-2016 IPR001294 Phytochrome GO:0006355|GO:0009584 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PRINTS PR01033 Phytochrome signature 458 476 6.2E-13 T 22-04-2016 IPR001294 Phytochrome GO:0006355|GO:0009584 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 PRINTS PR01033 Phytochrome signature 426 445 6.2E-13 T 22-04-2016 IPR001294 Phytochrome GO:0006355|GO:0009584 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 SUPERFAMILY SSF47384 499 582 8.83E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04865 704faf8fa3aa993cf73fb728b7e19702 735 Pfam PF00360 Phytochrome region 323 497 1.6E-48 T 22-04-2016 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 5 201 24.531 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 PANTHER PTHR21343:SF0 4 201 3.2E-37 T 22-04-2016 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 PANTHER PTHR21343 4 201 3.2E-37 T 22-04-2016 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 Pfam PF13500 AAA domain 7 190 3.5E-45 T 22-04-2016 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 PIRSF PIRSF006755 4 208 9.7E-41 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 Gene3D G3DSA:3.40.50.300 7 194 2.1E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 9 161 1.8E-33 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07935 b8252ed1ea1fbf3832a95565a82cb20e 210 SUPERFAMILY SSF52540 7 190 6.83E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 SUPERFAMILY SSF53474 2 256 1.11E-49 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 Gene3D G3DSA:3.40.50.1820 3 257 1.3E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.3E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 1.3E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 1.3E-9 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 PANTHER PTHR10992 2 157 3.0E-44 T 22-04-2016 MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 PANTHER PTHR10992 190 258 3.0E-44 T 22-04-2016 MED134_RS10960 c3bd9143c6f31d54c45e450e733fc241 263 Pfam PF00561 alpha/beta hydrolase fold 20 130 8.8E-21 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 SUPERFAMILY SSF54427 20 135 6.43E-25 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 Pfam PF12893 Putative lumazine-binding 22 135 1.0E-16 T 22-04-2016 MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 SUPERFAMILY SSF52317 146 367 1.64E-49 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 PANTHER PTHR11019:SF97 87 365 3.1E-17 T 22-04-2016 MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 Pfam PF01965 DJ-1/PfpI family 170 366 8.3E-9 T 22-04-2016 IPR002818 DJ-1/PfpI MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 PANTHER PTHR11019 87 365 3.1E-17 T 22-04-2016 MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 Gene3D G3DSA:3.40.50.880 135 368 4.8E-64 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03790 41fa9accb0cc70275f723de332b53519 371 Gene3D G3DSA:3.10.450.50 20 134 3.3E-26 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS10710 5830a8d1cbcbfc2e7ad0a169dcd6c66d 248 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 235 2.8E-33 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS10710 5830a8d1cbcbfc2e7ad0a169dcd6c66d 248 Gene3D G3DSA:3.40.50.10090 135 246 4.1E-19 T 22-04-2016 MED134_RS10710 5830a8d1cbcbfc2e7ad0a169dcd6c66d 248 Gene3D G3DSA:3.40.50.10090 11 130 2.1E-14 T 22-04-2016 MED134_RS10710 5830a8d1cbcbfc2e7ad0a169dcd6c66d 248 SUPERFAMILY SSF69618 4 242 3.79E-41 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 MED134_RS10710 5830a8d1cbcbfc2e7ad0a169dcd6c66d 248 PANTHER PTHR12390 1 247 1.5E-18 T 22-04-2016 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 Pfam PF01625 Peptide methionine sulfoxide reductase 8 159 1.4E-58 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 PANTHER PTHR10173:SF34 4 160 2.4E-75 T 22-04-2016 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 159 4.3E-53 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 164 33.982 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 Gene3D G3DSA:3.30.1060.10 3 159 1.6E-65 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 SUPERFAMILY SSF55068 3 170 2.49E-68 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 MED134_RS10080 b8803becb14260104ca2b2c64fa0b697 180 PANTHER PTHR10173 4 160 2.4E-75 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 MED134_RS08430 e7882ae83b5dd5f09ab61e27c24db921 151 SUPERFAMILY SSF46785 48 94 3.5E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08430 e7882ae83b5dd5f09ab61e27c24db921 151 Gene3D G3DSA:1.10.10.10 49 93 1.8E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Pfam PF00005 ABC transporter 27 184 4.8E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Pfam PF00005 ABC transporter 331 481 4.4E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Gene3D G3DSA:3.40.50.300 303 556 1.4E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Gene3D G3DSA:3.40.50.300 6 258 3.3E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 PANTHER PTHR24220:SF586 330 440 1.2E-158 T 22-04-2016 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 PANTHER PTHR24220:SF586 8 301 1.2E-158 T 22-04-2016 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 SUPERFAMILY SSF52540 6 256 1.77E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 276 3.2E-7 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 535 560 0.16 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 SUPERFAMILY SSF52540 304 554 5.09E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 PANTHER PTHR24220 330 440 1.2E-158 T 22-04-2016 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 PANTHER PTHR24220 8 301 1.2E-158 T 22-04-2016 MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 SMART SM00382 35 234 2.7E-18 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS08760 e986926d88285caad4c8cdf743894ef7 562 SMART SM00382 339 532 7.8E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 Pfam PF00691 OmpA family 460 548 3.8E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 SUPERFAMILY SSF49478 361 426 1.14E-5 T 22-04-2016 MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 Gene3D G3DSA:2.60.40.1120 368 440 1.1E-5 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 PANTHER PTHR30128 456 562 2.2E-33 T 22-04-2016 MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 PRINTS PR01021 OMPA domain signature 490 505 1.7E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 PRINTS PR01021 OMPA domain signature 460 482 1.7E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 PRINTS PR01021 OMPA domain signature 505 521 1.7E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 SUPERFAMILY SSF103088 450 564 1.57E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07010 cfcbfcdea95ecbf14003d3e485c9c5d8 568 Gene3D G3DSA:3.30.1330.60 450 566 2.6E-35 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 SMART SM00642 11 522 0.0018 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357 19 120 1.0E-31 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357 439 559 1.0E-31 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357 227 381 1.0E-31 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 SUPERFAMILY SSF51445 245 525 1.45E-52 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 SUPERFAMILY SSF51445 9 178 1.45E-52 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 Gene3D G3DSA:3.20.20.80 9 94 3.9E-81 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 Gene3D G3DSA:3.20.20.80 255 523 3.9E-81 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357:SF132 19 120 1.0E-31 T 22-04-2016 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357:SF132 439 559 1.0E-31 T 22-04-2016 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 PANTHER PTHR10357:SF132 227 381 1.0E-31 T 22-04-2016 MED134_RS01115 21de63069673f5c74380b1f3d4a85cf8 580 Gene3D G3DSA:3.90.400.10 95 176 1.1E-22 T 22-04-2016 MED134_RS06535 3315676cf9406cab602e4620272e1805 201 Gene3D G3DSA:3.90.550.10 14 103 1.4E-7 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS06535 3315676cf9406cab602e4620272e1805 201 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 28 111 2.8E-21 T 22-04-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated MED134_RS06535 3315676cf9406cab602e4620272e1805 201 PANTHER PTHR36529 25 177 1.8E-21 T 22-04-2016 MED134_RS06535 3315676cf9406cab602e4620272e1805 201 SUPERFAMILY SSF53448 3 151 3.82E-14 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS03625 e6fcf6ee781d65376de551474cdf09b1 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 125 4.6E-47 T 22-04-2016 IPR006056 RidA family MED134_RS03625 e6fcf6ee781d65376de551474cdf09b1 126 PANTHER PTHR11803 1 126 1.3E-47 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS03625 e6fcf6ee781d65376de551474cdf09b1 126 Pfam PF01042 Endoribonuclease L-PSP 8 125 1.7E-40 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS03625 e6fcf6ee781d65376de551474cdf09b1 126 SUPERFAMILY SSF55298 1 125 8.48E-41 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS03625 e6fcf6ee781d65376de551474cdf09b1 126 Gene3D G3DSA:3.30.1330.40 1 125 1.8E-45 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS11905 d621a98c1a478a6d1020752aeff7d169 336 PANTHER PTHR12147 112 328 1.9E-31 T 22-04-2016 MED134_RS11905 d621a98c1a478a6d1020752aeff7d169 336 SUPERFAMILY SSF53187 50 326 1.07E-58 T 22-04-2016 MED134_RS11905 d621a98c1a478a6d1020752aeff7d169 336 PANTHER PTHR12147:SF16 112 328 1.9E-31 T 22-04-2016 MED134_RS11905 d621a98c1a478a6d1020752aeff7d169 336 Gene3D G3DSA:3.40.630.10 52 327 1.2E-56 T 22-04-2016 MED134_RS11905 d621a98c1a478a6d1020752aeff7d169 336 Pfam PF04389 Peptidase family M28 112 313 3.6E-35 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Pfam PF13424 Tetratricopeptide repeat 125 194 8.3E-10 T 22-04-2016 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SUPERFAMILY SSF55874 448 601 1.96E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Gene3D G3DSA:1.25.40.10 74 270 7.7E-20 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 PANTHER PTHR24423 357 741 5.8E-102 T 22-04-2016 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SUPERFAMILY SSF52172 624 741 9.39E-33 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Gene3D G3DSA:1.10.287.130 370 439 1.6E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SUPERFAMILY SSF47384 365 442 1.29E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Gene3D G3DSA:3.30.565.10 450 601 2.9E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00448 626 737 2.5E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00028 208 241 11.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00028 164 197 13.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00028 124 156 0.32 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00028 84 117 21.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Pfam PF00072 Response regulator receiver domain 628 736 2.0E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00388 378 443 2.3E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 604 3.9E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Gene3D G3DSA:3.40.50.2300 623 741 8.8E-35 T 22-04-2016 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SUPERFAMILY SSF48452 74 277 6.45E-18 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 Pfam PF00512 His Kinase A (phospho-acceptor) domain 379 441 3.5E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 SMART SM00387 491 605 3.4E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 546 4.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 602 4.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 583 4.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS07860 dbf42a5ffaa3b681717880c586b52634 742 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 560 4.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 440 470 0.021 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 301 330 0.81 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 334 363 0.0041 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 407 436 1.6E-5 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 126 157 3100.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 267 297 1.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 93 122 0.24 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 196 225 290.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SMART SM00248 229 263 1400.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 PANTHER PTHR24198 65 116 3.0E-59 T 22-04-2016 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 PANTHER PTHR24198 405 489 3.0E-59 T 22-04-2016 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 PANTHER PTHR24198 186 364 3.0E-59 T 22-04-2016 MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SUPERFAMILY SSF48403 181 374 6.78E-51 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 Pfam PF12796 Ankyrin repeats (3 copies) 393 471 1.7E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 Pfam PF12796 Ankyrin repeats (3 copies) 272 364 1.4E-12 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SUPERFAMILY SSF48403 46 160 1.38E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 SUPERFAMILY SSF48403 401 482 6.78E-51 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 Gene3D G3DSA:1.25.40.20 67 259 1.1E-29 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 Gene3D G3DSA:1.25.40.20 392 486 6.7E-20 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00570 d4c3f8a7f0d86ebd73fc47ee4abd7150 499 Gene3D G3DSA:1.25.40.20 260 377 5.4E-29 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS00875 2b8216360c225fd7adbc3ca3756f58c4 92 Gene3D G3DSA:1.10.10.10 1 87 3.3E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00875 2b8216360c225fd7adbc3ca3756f58c4 92 SUPERFAMILY SSF46785 1 86 6.68E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00875 2b8216360c225fd7adbc3ca3756f58c4 92 PANTHER PTHR33204 1 85 5.9E-32 T 22-04-2016 MED134_RS00875 2b8216360c225fd7adbc3ca3756f58c4 92 Pfam PF01638 HxlR-like helix-turn-helix 3 86 5.2E-27 T 22-04-2016 IPR002577 Helix-turn-helix, HxlR type MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 SUPERFAMILY SSF53383 31 345 2.72E-70 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 Gene3D G3DSA:3.90.1150.10 237 347 4.9E-28 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 PANTHER PTHR11751:SF424 8 347 1.5E-113 T 22-04-2016 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 206 215 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 PANTHER PTHR11751 8 347 1.5E-113 T 22-04-2016 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 Gene3D G3DSA:3.40.640.10 37 236 2.8E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 346 3.5E-107 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 Pfam PF00155 Aminotransferase class I and II 46 344 2.3E-52 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS02440 fff9c609b88c4c9b4596e902c8eb8688 348 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 348 53.181 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 MED134_RS11430 c14cc73d361792bd7d5f0aa4b10554cb 269 PANTHER PTHR30373 9 197 5.7E-31 T 22-04-2016 MED134_RS11430 c14cc73d361792bd7d5f0aa4b10554cb 269 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 39 161 9.9E-36 T 22-04-2016 IPR007621 TPM domain MED134_RS11430 c14cc73d361792bd7d5f0aa4b10554cb 269 PANTHER PTHR30373:SF2 9 197 5.7E-31 T 22-04-2016 MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 Gene3D G3DSA:3.40.50.300 2 219 8.3E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 PANTHER PTHR24220:SF523 6 219 7.6E-88 T 22-04-2016 MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 Pfam PF00005 ABC transporter 21 158 2.1E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 SUPERFAMILY SSF52540 3 222 9.87E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 SMART SM00382 29 205 3.5E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS14125 e69410e9a226eb26ac049fc81055c399 297 PANTHER PTHR24220 6 219 7.6E-88 T 22-04-2016 MED134_RS04010 ab292ac8b1c0e684e174017b9edc41af 179 SUPERFAMILY SSF47413 3 58 9.12E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS04010 ab292ac8b1c0e684e174017b9edc41af 179 Pfam PF01381 Helix-turn-helix 4 57 5.6E-15 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS04010 ab292ac8b1c0e684e174017b9edc41af 179 SMART SM00530 3 57 8.7E-13 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS04010 ab292ac8b1c0e684e174017b9edc41af 179 Gene3D G3DSA:1.10.260.40 3 59 1.8E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 242 2.2E-26 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 SUPERFAMILY SSF51735 2 315 8.11E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 PANTHER PTHR10366:SF12 4 316 2.8E-95 T 22-04-2016 MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 Gene3D G3DSA:3.40.50.720 4 208 1.5E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 PANTHER PTHR10366 4 316 2.8E-95 T 22-04-2016 MED134_RS09735 ee23fb0af87c17e3bf7344a64150e94c 316 Gene3D G3DSA:3.90.25.10 209 315 9.8E-6 T 22-04-2016 MED134_RS11190 d52488af1bad74811ac280de866519da 432 SUPERFAMILY SSF48695 205 407 1.99E-37 T 22-04-2016 IPR011031 Multihaem cytochrome MED134_RS11190 d52488af1bad74811ac280de866519da 432 PANTHER PTHR39425 189 292 3.1E-39 T 22-04-2016 MED134_RS11190 d52488af1bad74811ac280de866519da 432 PANTHER PTHR39425 319 392 3.1E-39 T 22-04-2016 MED134_RS11190 d52488af1bad74811ac280de866519da 432 Pfam PF00034 Cytochrome c 38 125 9.2E-10 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS11190 d52488af1bad74811ac280de866519da 432 Gene3D G3DSA:3.90.10.10 335 431 1.9E-12 T 22-04-2016 MED134_RS11190 d52488af1bad74811ac280de866519da 432 Pfam PF14522 Cytochrome c7 and related cytochrome c 345 432 1.5E-9 T 22-04-2016 MED134_RS11190 d52488af1bad74811ac280de866519da 432 SUPERFAMILY SSF46626 16 123 1.67E-18 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS11190 d52488af1bad74811ac280de866519da 432 Gene3D G3DSA:1.10.760.10 35 124 1.5E-16 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS11190 d52488af1bad74811ac280de866519da 432 Gene3D G3DSA:3.90.10.10 237 282 3.2E-8 T 22-04-2016 MED134_RS00660 629311276588ac5bd7bcd03ec2ab8e6c 400 SUPERFAMILY SSF53756 19 387 1.57E-32 T 22-04-2016 MED134_RS00660 629311276588ac5bd7bcd03ec2ab8e6c 400 Gene3D G3DSA:3.40.50.2000 199 364 5.9E-9 T 22-04-2016 MED134_RS00660 629311276588ac5bd7bcd03ec2ab8e6c 400 Pfam PF13692 Glycosyl transferases group 1 209 354 1.3E-14 T 22-04-2016 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 Gene3D G3DSA:1.10.760.10 301 443 7.3E-38 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 SUPERFAMILY SSF46626 292 440 1.41E-33 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 Pfam PF03150 Di-haem cytochrome c peroxidase 307 453 2.2E-36 T 22-04-2016 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 SUPERFAMILY SSF46626 430 598 1.12E-30 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 Gene3D G3DSA:1.10.760.10 444 600 3.4E-40 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 PANTHER PTHR30600:SF5 276 606 1.5E-65 T 22-04-2016 MED134_RS13090 9a8bb66fdd8a9b41d5bf56a319813739 606 PANTHER PTHR30600 276 606 1.5E-65 T 22-04-2016 MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 SUPERFAMILY SSF56281 2 262 7.73E-49 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 SMART SM00849 34 233 1.7E-6 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 PANTHER PTHR12553:SF7 2 261 9.9E-61 T 22-04-2016 MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 Pfam PF12706 Beta-lactamase superfamily domain 46 234 2.2E-45 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 Gene3D G3DSA:3.60.15.10 2 262 1.4E-71 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS02050 031f3fce762971811ac4903b33d43dac 263 PANTHER PTHR12553 2 261 9.9E-61 T 22-04-2016 MED134_RS09990 d6eb84ca91f7329ecc0f0e948dfcd46d 196 Gene3D G3DSA:3.90.79.10 9 187 1.0E-50 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS09990 d6eb84ca91f7329ecc0f0e948dfcd46d 196 PANTHER PTHR11839 37 190 5.7E-36 T 22-04-2016 MED134_RS09990 d6eb84ca91f7329ecc0f0e948dfcd46d 196 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 10 186 1.8E-41 T 22-04-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 MED134_RS09990 d6eb84ca91f7329ecc0f0e948dfcd46d 196 SUPERFAMILY SSF55811 10 188 1.49E-40 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS09990 d6eb84ca91f7329ecc0f0e948dfcd46d 196 Pfam PF00293 NUDIX domain 46 162 2.7E-12 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 SUPERFAMILY SSF54909 64 151 4.29E-21 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 Gene3D G3DSA:1.10.10.10 1 54 3.0E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 SMART SM00344 3 112 2.8E-40 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 PANTHER PTHR30154:SF28 1 152 1.9E-49 T 22-04-2016 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 Gene3D G3DSA:3.30.70.920 55 152 2.3E-28 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 SUPERFAMILY SSF46785 2 62 2.4E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 7.6E-23 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 1.7E-13 T 22-04-2016 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 PANTHER PTHR30154 1 152 1.9E-49 T 22-04-2016 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.3E-11 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.3E-11 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS11555 74ce6a96f35294bb0f6975a5cbefd93b 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.3E-11 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS14100 e0cfe7761ee28107f77cb7e0b6917ef8 195 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 68 191 6.4E-37 T 22-04-2016 IPR007621 TPM domain MED134_RS14100 e0cfe7761ee28107f77cb7e0b6917ef8 195 PANTHER PTHR30373 62 190 4.3E-33 T 22-04-2016 MED134_RS14100 e0cfe7761ee28107f77cb7e0b6917ef8 195 PANTHER PTHR30373:SF2 62 190 4.3E-33 T 22-04-2016 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 PANTHER PTHR30560 1 437 1.7E-22 T 22-04-2016 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 Gene3D G3DSA:3.30.70.1050 1 119 1.1E-31 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 TIGRFAM TIGR00115 tig: trigger factor 12 417 8.5E-60 T 22-04-2016 IPR005215 Trigger factor GO:0015031 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 Gene3D G3DSA:1.10.3120.10 197 380 4.2E-21 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 SUPERFAMILY SSF102735 1 119 6.41E-30 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 PIRSF PIRSF003095 1 438 3.9E-42 T 22-04-2016 IPR005215 Trigger factor GO:0015031 MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 SUPERFAMILY SSF109998 252 437 3.92E-27 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS07480 1bec246b1bf9cc566c9a920b2b4412db 440 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 1.3E-33 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 SMART SM00892 59 252 1.3E-54 T 22-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 Gene3D G3DSA:3.40.570.10 48 267 3.6E-67 T 22-04-2016 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 118 126 - T 22-04-2016 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 PANTHER PTHR13966 55 259 1.7E-44 T 22-04-2016 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 SUPERFAMILY SSF54060 45 261 4.24E-64 T 22-04-2016 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 Pfam PF01223 DNA/RNA non-specific endonuclease 46 251 7.1E-51 T 22-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 MED134_RS06415 ef724b816f23b8280b170233c387cce5 269 SMART SM00477 60 252 8.1E-51 T 22-04-2016 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 MED134_RS07245 0cb3da168acb75a408599a541a107775 321 PANTHER PTHR30468:SF6 14 320 6.2E-62 T 22-04-2016 MED134_RS07245 0cb3da168acb75a408599a541a107775 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 191 314 1.1E-37 T 22-04-2016 IPR019257 Histidine-specific methyltransferase, SAM-dependent MED134_RS07245 0cb3da168acb75a408599a541a107775 321 SUPERFAMILY SSF53335 47 193 2.74E-6 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS07245 0cb3da168acb75a408599a541a107775 321 Gene3D G3DSA:3.40.50.150 54 144 2.6E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS07245 0cb3da168acb75a408599a541a107775 321 PANTHER PTHR30468 14 320 6.2E-62 T 22-04-2016 MED134_RS07245 0cb3da168acb75a408599a541a107775 321 PIRSF PIRSF018005 2 320 1.9E-83 T 22-04-2016 IPR017804 Methyltransferase EgtD-like MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 Pfam PF14437 MafB19-like deaminase 7 143 9.6E-32 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 PANTHER PTHR11079 7 146 8.9E-48 T 22-04-2016 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 Gene3D G3DSA:3.40.140.10 3 142 1.5E-51 T 22-04-2016 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 SUPERFAMILY SSF53927 3 143 9.67E-48 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 11 146 41.501 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 MED134_RS11050 cfaafeeabb27ddde2a6a375d1fd25074 149 PANTHER PTHR11079:SF72 7 146 8.9E-48 T 22-04-2016 MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 Pfam PF02153 Prephenate dehydrogenase 16 269 1.4E-64 T 22-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 SUPERFAMILY SSF51735 4 167 3.15E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 SUPERFAMILY SSF48179 170 279 1.13E-28 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 PANTHER PTHR21363 1 283 5.6E-55 T 22-04-2016 MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 Gene3D G3DSA:3.40.50.720 2 176 1.7E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05610 5101c9aff938dac8e5bc1eb2cdbd11e3 283 PANTHER PTHR21363:SF0 1 283 5.6E-55 T 22-04-2016 MED134_RS07850 9317a1bd2302862746563531397772e4 98 PRINTS PR00421 Thioredoxin family signature 63 74 3.0E-8 T 22-04-2016 MED134_RS07850 9317a1bd2302862746563531397772e4 98 PRINTS PR00421 Thioredoxin family signature 23 32 3.0E-8 T 22-04-2016 MED134_RS07850 9317a1bd2302862746563531397772e4 98 PRINTS PR00421 Thioredoxin family signature 15 23 3.0E-8 T 22-04-2016 MED134_RS07850 9317a1bd2302862746563531397772e4 98 Gene3D G3DSA:3.40.30.10 3 97 1.5E-34 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS07850 9317a1bd2302862746563531397772e4 98 Pfam PF00085 Thioredoxin 2 97 3.8E-30 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 MED134_RS07850 9317a1bd2302862746563531397772e4 98 PIRSF PIRSF000077 1 98 1.6E-35 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS07850 9317a1bd2302862746563531397772e4 98 SUPERFAMILY SSF52833 4 97 2.6E-35 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS07850 9317a1bd2302862746563531397772e4 98 ProSitePatterns PS00194 Thioredoxin family active site. 16 34 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 MED134_RS07850 9317a1bd2302862746563531397772e4 98 TIGRFAM TIGR01068 thioredoxin: thioredoxin 3 97 1.5E-34 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS07850 9317a1bd2302862746563531397772e4 98 PANTHER PTHR10438 2 97 7.9E-36 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS01235 9e1dd4e1899a8e2eaf25c48a68312d02 228 PANTHER PTHR34387 3 228 5.8E-47 T 22-04-2016 MED134_RS01235 9e1dd4e1899a8e2eaf25c48a68312d02 228 PANTHER PTHR34387:SF1 3 228 5.8E-47 T 22-04-2016 MED134_RS01235 9e1dd4e1899a8e2eaf25c48a68312d02 228 Pfam PF04402 Protein of unknown function (DUF541) 26 225 1.1E-46 T 22-04-2016 IPR007497 Protein of unknown function DUF541 MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 SUPERFAMILY SSF56601 4 301 1.62E-99 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 Hamap MF_00313 Glutaminase [glsA]. 4 305 41.199 T 22-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 PANTHER PTHR12544 7 299 3.8E-125 T 22-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 Pfam PF04960 Glutaminase 22 305 9.3E-110 T 22-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 Gene3D G3DSA:3.40.710.10 4 305 1.1E-115 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS06905 657bf84a03aa47b9eebdffaba9b017bd 305 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 305 2.0E-119 T 22-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 Gene3D G3DSA:3.40.50.300 1 214 4.6E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 SUPERFAMILY SSF52540 2 212 2.02E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 Pfam PF00005 ABC transporter 22 161 1.0E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 PANTHER PTHR24220:SF160 3 212 1.2E-51 T 22-04-2016 MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 PANTHER PTHR24220 3 212 1.2E-51 T 22-04-2016 MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS09375 d7e05ef82f469b3f959f50eaca49e56a 237 SMART SM00382 26 210 5.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 SUPERFAMILY SSF141734 9 114 2.62E-40 T 22-04-2016 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 27 99 6.1E-28 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 107 194 18.452 T 22-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 50 101 2.0E-17 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 1 199 33.742 T 22-04-2016 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19|UniPathway: UPA00031|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 PANTHER PTHR21256 1 198 1.6E-85 T 22-04-2016 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 111 196 7.5E-11 T 22-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 110 194 3.0E-27 T 22-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 MED134_RS02905 8d5afc8cf78e3bcb30fb5308ef2e7746 199 SUPERFAMILY SSF101386 109 198 3.71E-22 T 22-04-2016 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 SUPERFAMILY SSF48452 120 317 6.83E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 Pfam PF13174 Tetratricopeptide repeat 64 87 0.013 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 Gene3D G3DSA:1.25.40.10 20 312 3.8E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 Pfam PF13432 Tetratricopeptide repeat 277 306 0.017 T 22-04-2016 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 PANTHER PTHR23083 24 322 1.9E-15 T 22-04-2016 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 SUPERFAMILY SSF48452 24 144 1.48E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 SMART SM00028 54 87 6.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 SMART SM00028 169 202 310.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS12035 3127e054806ef97d2d3415207e3e7fff 322 SMART SM00028 276 309 0.055 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Gene3D G3DSA:3.30.1490.20 21 98 2.0E-32 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 266 291 - T 22-04-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 391 3.0E-141 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Pfam PF00549 CoA-ligase 271 390 1.4E-23 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 396 39.022 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Gene3D G3DSA:3.40.50.261 250 391 2.1E-61 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 SUPERFAMILY SSF56059 1 247 1.41E-72 T 22-04-2016 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 PANTHER PTHR11815:SF1 1 391 7.1E-201 T 22-04-2016 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 PANTHER PTHR11815 1 391 7.1E-201 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Pfam PF08442 ATP-grasp domain 2 210 1.8E-67 T 22-04-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 PIRSF PIRSF001554 1 396 2.9E-143 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 Gene3D G3DSA:3.30.470.20 99 247 6.8E-54 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS13495 0063989900ceca1989d38e190cf17e9f 396 SUPERFAMILY SSF52210 249 393 1.57E-49 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Pfam PF03445 Putative nucleotidyltransferase DUF294 315 453 5.9E-43 T 22-04-2016 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SUPERFAMILY SSF81301 314 417 3.92E-5 T 22-04-2016 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 490 630 2.3E-31 T 22-04-2016 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SMART SM00116 173 220 5.1E-7 T 22-04-2016 IPR000644 CBS domain MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SMART SM00116 237 288 0.0049 T 22-04-2016 IPR000644 CBS domain MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SMART SM00100 18 138 8.0E-6 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SUPERFAMILY SSF54631 171 284 1.18E-21 T 22-04-2016 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Gene3D G3DSA:3.10.580.10 171 284 1.1E-23 T 22-04-2016 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Gene3D G3DSA:2.60.120.10 7 140 3.5E-17 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Pfam PF00571 CBS domain 171 220 2.7E-8 T 22-04-2016 IPR000644 CBS domain MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Pfam PF00571 CBS domain 231 284 1.1E-6 T 22-04-2016 IPR000644 CBS domain MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 SUPERFAMILY SSF51206 7 131 2.62E-20 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 PANTHER PTHR11911 171 284 7.6E-19 T 22-04-2016 MED134_RS08080 d19da7a5d143157fbd95601c546a1d86 636 Pfam PF00027 Cyclic nucleotide-binding domain 38 121 4.1E-12 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS11440 62e809b693673ce9629101f18e683112 202 Gene3D G3DSA:1.20.1440.20 25 198 2.5E-56 T 22-04-2016 IPR023353 LemA-like domain MED134_RS11440 62e809b693673ce9629101f18e683112 202 SUPERFAMILY SSF140478 32 187 2.48E-49 T 22-04-2016 IPR023353 LemA-like domain MED134_RS11440 62e809b693673ce9629101f18e683112 202 Pfam PF04011 LemA family 9 198 1.8E-63 T 22-04-2016 IPR007156 LemA MED134_RS11440 62e809b693673ce9629101f18e683112 202 PANTHER PTHR34478:SF2 2 201 2.2E-72 T 22-04-2016 MED134_RS11440 62e809b693673ce9629101f18e683112 202 PANTHER PTHR34478 2 201 2.2E-72 T 22-04-2016 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 SUPERFAMILY SSF48179 198 286 3.06E-25 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 PANTHER PTHR11374 1 403 1.4E-145 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 PIRSF PIRSF500136 1 403 6.4E-137 T 22-04-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 Gene3D G3DSA:3.40.50.720 230 399 1.2E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 391 2.1E-111 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 313 387 1.1E-15 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 SUPERFAMILY SSF51735 6 190 9.44E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 Gene3D G3DSA:3.40.50.720 4 219 1.9E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 181 8.3E-50 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 SMART SM00984 313 403 5.3E-14 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 SUPERFAMILY SSF52413 311 400 1.18E-17 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 PIRSF PIRSF000124 4 402 1.6E-68 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 PANTHER PTHR11374:SF4 1 403 1.4E-145 T 22-04-2016 MED134_RS01380 fa7496b110d14bc8cbc07bfc846fbe9b 403 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 285 3.2E-24 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Gene3D G3DSA:3.90.180.10 88 170 7.1E-20 T 22-04-2016 IPR011032 GroES-like MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Gene3D G3DSA:3.90.180.10 6 54 7.1E-20 T 22-04-2016 IPR011032 GroES-like MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Pfam PF00107 Zinc-binding dehydrogenase 178 298 6.8E-18 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SUPERFAMILY SSF55347 512 660 3.27E-17 T 22-04-2016 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SUPERFAMILY SSF51735 382 548 7.35E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 PANTHER PTHR22604 349 706 1.3E-55 T 22-04-2016 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SMART SM00829 59 265 0.0064 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Gene3D G3DSA:3.40.50.720 171 286 1.3E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Gene3D G3DSA:3.40.50.720 389 514 2.6E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 390 507 1.2E-18 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 Gene3D G3DSA:3.30.360.10 515 701 8.0E-23 T 22-04-2016 MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SUPERFAMILY SSF50129 87 176 1.84E-21 T 22-04-2016 IPR011032 GroES-like MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SUPERFAMILY SSF50129 9 55 1.84E-21 T 22-04-2016 IPR011032 GroES-like MED134_RS01400 544089c1cedb6103df61a151e5e8eeb3 706 SUPERFAMILY SSF51735 140 298 1.11E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Pfam PF02817 e3 binding domain 269 304 1.7E-15 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 323 547 1.6E-85 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 SUPERFAMILY SSF51230 130 216 1.3E-26 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 155 184 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 SUPERFAMILY SSF51230 2 88 1.27E-26 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 PANTHER PTHR23151 24 547 1.3E-191 T 22-04-2016 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Gene3D G3DSA:4.10.320.10 264 310 6.5E-20 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 133 547 2.4E-137 T 22-04-2016 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 SUPERFAMILY SSF47005 263 307 7.85E-13 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 PANTHER PTHR23151:SF9 24 547 1.3E-191 T 22-04-2016 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Gene3D G3DSA:3.30.559.10 320 548 2.0E-86 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 SUPERFAMILY SSF52777 324 547 5.78E-83 T 22-04-2016 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Pfam PF00364 Biotin-requiring enzyme 133 204 4.4E-19 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Pfam PF00364 Biotin-requiring enzyme 4 76 4.6E-20 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Gene3D G3DSA:2.40.50.100 2 95 1.2E-32 T 22-04-2016 MED134_RS11900 dd786259fea3c1ff8dbe62b6fd67dfa1 548 Gene3D G3DSA:2.40.50.100 131 216 7.3E-30 T 22-04-2016 MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 PANTHER PTHR31793 2 130 6.5E-39 T 22-04-2016 MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 Pfam PF03061 Thioesterase superfamily 18 101 7.1E-14 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 PANTHER PTHR31793:SF9 2 130 6.5E-39 T 22-04-2016 MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 SUPERFAMILY SSF54637 4 130 3.92E-38 T 22-04-2016 IPR029069 HotDog domain MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 121 1.1E-24 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 Gene3D G3DSA:3.10.129.10 4 129 1.5E-41 T 22-04-2016 IPR029069 HotDog domain MED134_RS13720 b3855eac836c4f67e38501be89348db2 130 PIRSF PIRSF003230 1 130 1.8E-38 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 SUPERFAMILY SSF52540 12 195 1.83E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09525 6476a938d5723c8989f408e81e279579 199 Pfam PF00625 Guanylate kinase 14 190 1.4E-45 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MED134_RS09525 6476a938d5723c8989f408e81e279579 199 PANTHER PTHR23117 14 189 1.4E-69 T 22-04-2016 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 14 194 6.0E-63 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 Gene3D G3DSA:3.40.50.300 97 196 1.4E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09525 6476a938d5723c8989f408e81e279579 199 Gene3D G3DSA:3.40.50.300 9 60 2.1E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09525 6476a938d5723c8989f408e81e279579 199 Hamap MF_00328 Guanylate kinase [gmk]. 12 198 33.724 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 ProSitePatterns PS00856 Guanylate kinase-like signature. 49 66 - T 22-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 PANTHER PTHR23117:SF13 14 189 1.4E-69 T 22-04-2016 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 Gene3D G3DSA:3.30.63.10 61 96 4.8E-21 T 22-04-2016 MED134_RS09525 6476a938d5723c8989f408e81e279579 199 SMART SM00072 13 198 1.5E-43 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 PANTHER PTHR22604:SF123 1 378 7.5E-56 T 22-04-2016 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 SUPERFAMILY SSF51735 2 169 3.35E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 SUPERFAMILY SSF55347 143 310 6.87E-30 T 22-04-2016 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 PANTHER PTHR22604 1 378 7.5E-56 T 22-04-2016 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 Gene3D G3DSA:3.30.360.10 325 372 3.4E-32 T 22-04-2016 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 Gene3D G3DSA:3.30.360.10 157 279 3.4E-32 T 22-04-2016 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 Gene3D G3DSA:3.40.50.720 1 156 9.6E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 261 5.1E-7 T 22-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 MED134_RS09560 056713715ada4a16dc503b1d7dec77c2 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 136 1.5E-17 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 MED134_RS03910 d3608d1bc16e31ea306a1f06946f0b54 230 SUPERFAMILY SSF48498 91 226 8.89E-30 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MED134_RS03910 d3608d1bc16e31ea306a1f06946f0b54 230 Gene3D G3DSA:1.10.357.10 21 206 7.8E-5 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 SUPERFAMILY SSF46548 302 411 5.58E-23 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 PANTHER PTHR11921:SF22 114 447 6.1E-47 T 22-04-2016 MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 PANTHER PTHR11921 114 447 6.1E-47 T 22-04-2016 MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 Pfam PF13183 4Fe-4S dicluster domain 314 396 2.2E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 Gene3D G3DSA:1.10.1060.10 291 413 2.9E-31 T 22-04-2016 MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 SUPERFAMILY SSF103501 10 257 1.19E-13 T 22-04-2016 IPR023234 NarG-like domain MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 382 393 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS03605 55cdf4aa68bf0bd44f63123bc438d279 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 316 327 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS01715 ab501a17b6504ca136f157877bfc5b37 122 Pfam PF12487 Protein of unknown function (DUF3703) 9 117 1.6E-41 T 22-04-2016 IPR022172 Protein of unknown function DUF3703 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 Gene3D G3DSA:1.10.10.10 116 174 4.1E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 PANTHER PTHR30173 6 174 1.8E-38 T 22-04-2016 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 78 - T 22-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 SUPERFAMILY SSF88659 113 174 6.54E-12 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 PANTHER PTHR30173:SF31 6 174 1.8E-38 T 22-04-2016 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 Pfam PF04545 Sigma-70, region 4 125 172 3.8E-10 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 SUPERFAMILY SSF88946 7 97 1.88E-25 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 Pfam PF04542 Sigma-70 region 2 24 92 2.4E-18 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 172 1.1E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05805 6997a899b19b17da2127568be7ea43ba 184 Gene3D G3DSA:1.10.1740.10 6 106 3.3E-28 T 22-04-2016 MED134_RS14085 71ba3fbd84bc8b3174a19246611b4d84 281 Pfam PF11138 Protein of unknown function (DUF2911) 27 172 4.0E-50 T 22-04-2016 IPR021314 Protein of unknown function DUF2911 MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 SUPERFAMILY SSF48317 41 456 5.36E-36 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 PANTHER PTHR34599:SF1 120 456 1.7E-22 T 22-04-2016 MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 PANTHER PTHR34599:SF1 32 98 1.7E-22 T 22-04-2016 MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 Pfam PF01569 PAP2 superfamily 319 450 4.3E-11 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 Gene3D G3DSA:1.20.144.10 44 186 2.4E-8 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 Gene3D G3DSA:1.10.606.10 188 457 4.8E-65 T 22-04-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 PANTHER PTHR34599 120 456 1.7E-22 T 22-04-2016 MED134_RS04695 f27ed49f9f34bc82adaebd96123a9c8b 463 PANTHER PTHR34599 32 98 1.7E-22 T 22-04-2016 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 456 3.0E-193 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 Gene3D G3DSA:3.30.499.10 322 457 5.6E-56 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PANTHER PTHR11670 1 455 1.2E-214 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 SUPERFAMILY SSF53732 1 456 2.22E-153 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 459 52.333 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 Gene3D G3DSA:3.30.499.10 2 164 1.2E-22 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 ProSitePatterns PS01244 Aconitase family signature 2. 392 405 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PANTHER PTHR11670:SF12 1 455 1.2E-214 T 22-04-2016 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 Gene3D G3DSA:3.40.1060.10 167 280 4.1E-36 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 Pfam PF00330 Aconitase family (aconitate hydratase) 7 450 3.0E-143 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 336 347 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 195 208 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 133 148 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 82 95 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 119 132 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 392 405 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 108 116 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 209 222 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11800 4f174f76cc14fafada8581c123167d9f 461 PRINTS PR00415 Aconitase family signature 286 300 2.5E-39 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 270 289 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 239 257 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 72 89 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 59 72 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 186 207 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00690 Adhesin family signature 28 46 2.1E-44 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PANTHER PTHR30477:SF16 7 304 9.6E-104 T 22-04-2016 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 53 71 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 262 280 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 28 49 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 186 203 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 72 91 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 283 301 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PRINTS PR00691 Adhesin B signature 128 147 2.4E-29 T 22-04-2016 IPR006129 Adhesin B GO:0007155 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 SUPERFAMILY SSF53807 25 305 4.17E-79 T 22-04-2016 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 303 2.6E-75 T 22-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 Gene3D G3DSA:3.40.50.1980 24 178 9.4E-47 T 22-04-2016 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 PANTHER PTHR30477 7 304 9.6E-104 T 22-04-2016 MED134_RS10265 68d0131716468c11b735fb2d31b5ad59 305 Gene3D G3DSA:3.40.50.1980 179 305 2.1E-44 T 22-04-2016 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 PANTHER PTHR10314 20 47 1.8E-21 T 22-04-2016 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 PANTHER PTHR10314 70 167 1.8E-21 T 22-04-2016 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 PANTHER PTHR10314:SF4 20 47 1.8E-21 T 22-04-2016 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 PANTHER PTHR10314:SF4 70 167 1.8E-21 T 22-04-2016 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 Pfam PF00290 Tryptophan synthase alpha chain 7 243 2.0E-75 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 Gene3D G3DSA:3.20.20.70 1 251 1.6E-88 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 10 252 29.397 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 44 57 - T 22-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 SUPERFAMILY SSF51366 1 252 1.22E-80 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS13015 f5ece80a21970ee8546446827f1b1f53 253 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 242 9.7E-70 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 182 241 9.8E-19 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 TIGRFAM TIGR00277 HDIG: HDIG domain 270 317 3.6E-8 T 22-04-2016 IPR006675 HDIG domain MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 PANTHER PTHR13734:SF5 5 459 4.7E-99 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Pfam PF01966 HD domain 259 348 4.7E-14 T 22-04-2016 IPR006674 HD domain MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Gene3D G3DSA:1.10.3090.10 400 428 2.9E-58 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Gene3D G3DSA:1.10.3090.10 153 331 2.9E-58 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Pfam PF01743 Poly A polymerase head domain 27 155 2.7E-24 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 Gene3D G3DSA:3.30.460.10 9 151 5.4E-35 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 SUPERFAMILY SSF81891 153 461 5.62E-61 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 PANTHER PTHR13734 5 459 4.7E-99 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 SUPERFAMILY SSF81301 5 152 1.2E-30 T 22-04-2016 MED134_RS14150 8749cd37f4aeae818efca31ada7b2338 471 SMART SM00471 254 378 0.0049 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS05670 4b76fd22442afe34626f5f814bc44515 151 Pfam PF13508 Acetyltransferase (GNAT) domain 54 129 1.8E-10 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS05670 4b76fd22442afe34626f5f814bc44515 151 SUPERFAMILY SSF55729 30 138 1.01E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS05670 4b76fd22442afe34626f5f814bc44515 151 Gene3D G3DSA:3.40.630.30 19 137 1.2E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 6.4E-15 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 4.8E-214 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PANTHER PTHR23115:SF112 1 393 5.4E-233 T 22-04-2016 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 1.5E-31 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 SUPERFAMILY SSF50447 205 302 1.95E-27 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Gene3D G3DSA:3.40.50.300 5 211 7.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PANTHER PTHR23115 1 393 5.4E-233 T 22-04-2016 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 SUPERFAMILY SSF52540 7 219 2.68E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Gene3D G3DSA:2.40.30.10 301 394 2.5E-43 T 22-04-2016 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 SUPERFAMILY SSF50465 303 395 9.5E-35 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.3E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 5.3E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.3E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.3E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.3E-25 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Gene3D G3DSA:2.40.30.10 212 299 8.5E-33 T 22-04-2016 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 57.725 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 145 2.7E-14 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS04925 347d65d12d53822f49761a2746b0a36e 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 199 1.7E-57 T 22-04-2016 MED134_RS06610 f722d36ff883b729bb8182ef446e361a 199 PANTHER PTHR23026:SF101 1 199 5.5E-44 T 22-04-2016 MED134_RS06610 f722d36ff883b729bb8182ef446e361a 199 PANTHER PTHR23026 1 199 5.5E-44 T 22-04-2016 MED134_RS06610 f722d36ff883b729bb8182ef446e361a 199 SUPERFAMILY SSF55469 1 196 1.05E-41 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS06610 f722d36ff883b729bb8182ef446e361a 199 Gene3D G3DSA:3.40.109.10 1 198 5.7E-51 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS06610 f722d36ff883b729bb8182ef446e361a 199 Pfam PF00881 Nitroreductase family 8 173 5.2E-20 T 22-04-2016 IPR029479 Nitroreductase MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 Gene3D G3DSA:3.40.50.200 100 449 1.1E-54 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PANTHER PTHR10795:SF332 145 465 8.0E-39 T 22-04-2016 MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 215 228 2.7E-7 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 168 187 2.7E-7 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 391 407 2.7E-7 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 SUPERFAMILY SSF52743 86 461 1.57E-62 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 SUPERFAMILY SSF52743 5 55 1.57E-62 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 465 536 1.2E-14 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PIRSF PIRSF037903 1 459 1.4E-187 T 22-04-2016 IPR017317 Peptidase S8A, subtilisin-related, bacteroidetes-2 MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 PANTHER PTHR10795 145 465 8.0E-39 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 173 184 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 392 402 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site MED134_RS03350 a3eab4e941240d3ead0bcc479cf12ec8 537 Pfam PF00082 Subtilase family 168 433 1.3E-35 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS13425 6da42e7f3f7336eba430e09786720ed2 291 Gene3D G3DSA:3.20.20.70 3 269 1.8E-84 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS13425 6da42e7f3f7336eba430e09786720ed2 291 SUPERFAMILY SSF51569 2 286 3.91E-67 T 22-04-2016 MED134_RS13425 6da42e7f3f7336eba430e09786720ed2 291 PANTHER PTHR23416 1 287 7.4E-86 T 22-04-2016 MED134_RS13425 6da42e7f3f7336eba430e09786720ed2 291 PANTHER PTHR23416:SF1 1 287 7.4E-86 T 22-04-2016 MED134_RS13425 6da42e7f3f7336eba430e09786720ed2 291 Pfam PF03102 NeuB family 27 270 6.3E-66 T 22-04-2016 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 MED134_RS07450 714c59dc2df59a99592e241360e64926 204 Pfam PF01810 LysE type translocator 15 195 1.6E-11 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PANTHER PTHR19370:SF93 4 263 1.8E-48 T 22-04-2016 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 SUPERFAMILY SSF63380 3 105 6.35E-24 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PANTHER PTHR19370 4 263 1.8E-48 T 22-04-2016 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Pfam PF00970 Oxidoreductase FAD-binding domain 8 103 9.9E-14 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 55 62 2.7E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 211 219 2.7E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 2.7E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 141 150 2.7E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 267 339 4.2E-13 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00406 Cytochrome B5 reductase signature 90 104 3.5E-7 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00406 Cytochrome B5 reductase signature 55 62 3.5E-7 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00406 Cytochrome B5 reductase signature 211 219 3.5E-7 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 PRINTS PR00406 Cytochrome B5 reductase signature 116 135 3.5E-7 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 SUPERFAMILY SSF52343 93 241 1.11E-29 T 22-04-2016 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Gene3D G3DSA:2.40.30.10 2 93 5.9E-25 T 22-04-2016 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Gene3D G3DSA:3.10.20.30 238 348 2.6E-28 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Gene3D G3DSA:3.40.50.80 94 237 4.8E-33 T 22-04-2016 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 SUPERFAMILY SSF54292 235 347 8.39E-25 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 Pfam PF00175 Oxidoreductase NAD-binding domain 119 225 1.2E-15 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MED134_RS09365 d08e48bd6738f83a5b513876cfc5c368 350 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 296 304 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 PANTHER PTHR23416 49 194 2.2E-30 T 22-04-2016 MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 Gene3D G3DSA:2.160.10.10 64 193 5.3E-34 T 22-04-2016 MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 SUPERFAMILY SSF51161 2 192 4.44E-41 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 149 177 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 PANTHER PTHR23416:SF23 49 194 2.2E-30 T 22-04-2016 MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 144 174 0.0015 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 139 4.3E-7 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 1 189 9.6E-62 T 22-04-2016 IPR020019 Sialic acid O-acyltransferase NeuD-like MED134_RS01420 90d137d43a5f0574f8aa8f1b3bc1547e 197 Gene3D G3DSA:3.40.50.20 1 63 7.3E-19 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS11205 7de70d489d94c012ae11908efacdf8bc 176 PANTHER PTHR40394:SF2 8 149 4.4E-14 T 22-04-2016 MED134_RS11205 7de70d489d94c012ae11908efacdf8bc 176 PANTHER PTHR40394 8 149 4.4E-14 T 22-04-2016 MED134_RS11205 7de70d489d94c012ae11908efacdf8bc 176 Pfam PF11821 Protein of unknown function (DUF3341) 5 170 3.3E-61 T 22-04-2016 IPR021776 Protein of unknown function DUF3341 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 89 2.6E-42 T 22-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.057 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 22-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 Pfam PF00203 Ribosomal protein S19 3 83 2.0E-35 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 PANTHER PTHR11880 1 88 1.4E-48 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 PIRSF PIRSF002144 1 93 5.5E-32 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-23 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-23 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-23 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 Gene3D G3DSA:3.30.860.10 1 91 4.4E-40 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 MED134_RS12255 d49f4e610d6c2bef50adc1884e39f3ab 93 SUPERFAMILY SSF54570 3 84 2.09E-33 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 Pfam PF02682 Allophanate hydrolase subunit 1 5 202 6.2E-57 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 SUPERFAMILY SSF160467 5 94 1.57E-5 T 22-04-2016 MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 2.6E-47 T 22-04-2016 IPR010016 KipI family MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 SMART SM00796 4 203 1.6E-59 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 PANTHER PTHR34698:SF2 1 224 1.0E-70 T 22-04-2016 MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 Gene3D G3DSA:2.40.100.10 89 222 1.7E-43 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 PANTHER PTHR34698 1 224 1.0E-70 T 22-04-2016 MED134_RS04760 6e3bc58c348e26576f7f2827e04444ae 224 SUPERFAMILY SSF50891 90 219 3.6E-42 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.40.170.20 435 817 1.0E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.40.170.20 302 379 1.0E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.40.170.20 228 244 1.0E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.40.170.20 869 1022 1.0E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 TIGRFAM TIGR04057 SusC_RagA_signa: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region 200 230 1.8E-15 T 22-04-2016 IPR023997 TonB-dependent outer membrane protein SusC/RagA, conserved site UniPathway: UPA00153 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 SUPERFAMILY SSF49464 25 106 2.88E-17 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Pfam PF07715 TonB-dependent Receptor Plug Domain 118 224 7.2E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.60.40.1120 27 117 8.6E-13 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Gene3D G3DSA:2.170.130.10 118 227 6.6E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 SUPERFAMILY SSF56935 440 788 2.46E-93 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 SUPERFAMILY SSF56935 104 248 2.46E-93 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 SUPERFAMILY SSF56935 293 381 2.46E-93 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 SUPERFAMILY SSF56935 860 1022 2.46E-93 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 PANTHER PTHR11532 1 391 1.4E-221 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 PANTHER PTHR11532 511 1020 1.4E-221 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 27 1022 2.2E-233 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 PANTHER PTHR11532:SF57 1 391 1.4E-221 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 PANTHER PTHR11532:SF57 511 1020 1.4E-221 T 22-04-2016 MED134_RS10495 6aafdc40f2e8e648f3b75886c7f06c7a 1022 Pfam PF13715 CarboxypepD_reg-like domain 27 108 2.0E-17 T 22-04-2016 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 PANTHER PTHR32234 177 502 5.3E-89 T 22-04-2016 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 PANTHER PTHR32234 521 575 5.3E-89 T 22-04-2016 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 PANTHER PTHR32234:SF0 177 502 5.3E-89 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 PANTHER PTHR32234:SF0 521 575 5.3E-89 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 Pfam PF13899 Thioredoxin-like 521 582 8.4E-12 T 22-04-2016 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 194 387 7.4E-14 T 22-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 Pfam PF11412 Disulphide bond corrector protein DsbC 33 136 3.8E-9 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 Gene3D G3DSA:3.40.30.10 518 654 8.7E-40 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 SUPERFAMILY SSF52833 462 482 2.66E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04790 25cd3eaed390bca1a1596bc4f25833f0 656 SUPERFAMILY SSF52833 514 650 2.66E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 624 635 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 PANTHER PTHR11748:SF35 5 180 5.2E-110 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 PANTHER PTHR11748 5 180 5.2E-110 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Pfam PF01565 FAD binding domain 37 171 7.0E-33 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 SUPERFAMILY SSF46548 501 643 7.85E-12 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 SUPERFAMILY SSF56176 5 273 3.23E-50 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Pfam PF02913 FAD linked oxidases, C-terminal domain 274 522 3.7E-47 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Gene3D G3DSA:3.30.43.10 5 87 9.5E-15 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 SUPERFAMILY SSF55103 279 532 5.72E-51 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Gene3D G3DSA:1.10.1060.10 499 654 6.3E-15 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 PANTHER PTHR11748:SF35 240 571 5.2E-110 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 PANTHER PTHR11748 240 571 5.2E-110 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Pfam PF13534 4Fe-4S dicluster domain 561 639 5.7E-9 T 22-04-2016 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Gene3D G3DSA:3.30.465.10 216 273 1.8E-33 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MED134_RS03565 0a25fff76fd0a02d69bbd45e8328f69c 970 Gene3D G3DSA:3.30.465.10 91 181 1.8E-33 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 SUPERFAMILY SSF53067 136 292 2.66E-34 T 22-04-2016 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 PANTHER PTHR30005:SF0 7 288 1.7E-58 T 22-04-2016 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 Gene3D G3DSA:3.30.420.40 4 125 3.2E-38 T 22-04-2016 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 SUPERFAMILY SSF53067 6 125 1.58E-33 T 22-04-2016 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 Pfam PF02541 Ppx/GppA phosphatase family 43 293 1.1E-39 T 22-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 PANTHER PTHR30005 7 288 1.7E-58 T 22-04-2016 MED134_RS01010 f2b6cea8dfe8e746a3382630d40da155 295 Gene3D G3DSA:3.30.420.150 135 292 1.3E-26 T 22-04-2016 MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 PANTHER PTHR34388 1 313 4.0E-56 T 22-04-2016 MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 SUPERFAMILY SSF52540 13 204 2.35E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 Gene3D G3DSA:1.10.8.60 141 229 1.4E-18 T 22-04-2016 MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 Pfam PF06144 DNA polymerase III, delta subunit 20 187 4.3E-30 T 22-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 SUPERFAMILY SSF48019 210 319 3.74E-9 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 Gene3D G3DSA:3.40.50.300 9 132 9.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03630 04334b170bba3bb77c10e6f036370323 334 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 332 1.2E-59 T 22-04-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 PANTHER PTHR22572 6 422 1.5E-140 T 22-04-2016 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 97 105 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 SUPERFAMILY SSF53448 2 272 1.13E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04470 2b381e5f209688c487045ab479f47107 422 SUPERFAMILY SSF53448 369 384 1.13E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04470 2b381e5f209688c487045ab479f47107 422 PANTHER PTHR22572:SF79 6 422 1.5E-140 T 22-04-2016 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 Pfam PF00483 Nucleotidyl transferase 7 269 5.6E-66 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 SUPERFAMILY SSF51161 286 422 1.17E-22 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS04470 2b381e5f209688c487045ab479f47107 422 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 388 1.4E-133 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 Gene3D G3DSA:3.90.550.10 5 329 8.3E-73 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04470 2b381e5f209688c487045ab479f47107 422 Gene3D G3DSA:2.160.10.10 330 404 8.0E-4 T 22-04-2016 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 205 215 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04470 2b381e5f209688c487045ab479f47107 422 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS03610 3bb5fb99e2c25acc5a2e2416f01984f0 314 Pfam PF02470 MlaD protein 36 110 9.7E-14 T 22-04-2016 IPR003399 Mce/MlaD MED134_RS03610 3bb5fb99e2c25acc5a2e2416f01984f0 314 PANTHER PTHR33371 8 299 8.4E-18 T 22-04-2016 MED134_RS02025 fb400a214e9b4a26c582faa94fe008d9 641 PANTHER PTHR37464 2 369 9.4E-23 T 22-04-2016 MED134_RS02025 fb400a214e9b4a26c582faa94fe008d9 641 Pfam PF07584 Aerotolerance regulator N-terminal 1 76 1.9E-17 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal MED134_RS02025 fb400a214e9b4a26c582faa94fe008d9 641 PANTHER PTHR37464:SF1 2 369 9.4E-23 T 22-04-2016 MED134_RS02025 fb400a214e9b4a26c582faa94fe008d9 641 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 81 7.3E-17 T 22-04-2016 IPR011933 Double transmembrane domain MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 PANTHER PTHR11070 1 528 2.3E-195 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 PANTHER PTHR11070 544 659 2.3E-195 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Pfam PF13361 UvrD-like helicase C-terminal domain 286 631 9.7E-73 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 SUPERFAMILY SSF52540 8 657 3.35E-168 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:3.40.50.300 200 294 1.2E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:3.40.50.300 7 112 1.2E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 PANTHER PTHR11070:SF7 1 528 2.3E-195 T 22-04-2016 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 PANTHER PTHR11070:SF7 544 659 2.3E-195 T 22-04-2016 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:3.40.50.300 295 397 2.9E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:3.40.50.300 567 657 2.9E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:1.10.486.10 398 555 1.3E-41 T 22-04-2016 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 280 9.0E-72 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 MED134_RS03670 c4f4c5f1625b3bddd9d919307bff88be 778 Gene3D G3DSA:1.10.10.160 116 199 8.5E-21 T 22-04-2016 IPR013986 DExx box DNA helicase domain MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 Gene3D G3DSA:3.40.50.1820 37 310 5.2E-51 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 144 157 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 130 143 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 84 99 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 64 82 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 286 308 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00412 Epoxide hydrolase signature 251 267 3.0E-17 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 Pfam PF00561 alpha/beta hydrolase fold 58 297 5.8E-18 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PANTHER PTHR10992 48 311 2.1E-49 T 22-04-2016 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 144 157 5.4E-12 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 99 5.4E-12 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 253 267 5.4E-12 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS08835 529efc6c31cb3ce5f62651cc2d46e20a 311 SUPERFAMILY SSF53474 37 311 5.3E-49 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS04095 47417ec1d414fa66652628925761cb4d 99 PIRSF PIRSF029218 1 99 2.3E-31 T 22-04-2016 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 MED134_RS04095 47417ec1d414fa66652628925761cb4d 99 PANTHER PTHR33755 1 97 1.2E-14 T 22-04-2016 MED134_RS04095 47417ec1d414fa66652628925761cb4d 99 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 92 2.0E-15 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 Pfam PF01063 Amino-transferase class IV 70 310 2.4E-32 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 Gene3D G3DSA:3.20.10.10 173 340 5.7E-51 T 22-04-2016 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 45 353 1.7E-97 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 PIRSF PIRSF006468 2 354 9.2E-111 T 22-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 Gene3D G3DSA:3.30.470.10 4 172 1.5E-62 T 22-04-2016 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 SUPERFAMILY SSF56752 6 350 5.62E-97 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 PANTHER PTHR11825 17 352 2.3E-110 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS06930 3f4f1c1361763ee029c5b88eea33348b 354 ProSitePatterns PS00770 Aminotransferases class-IV signature. 231 260 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 SMART SM00448 4 112 3.4E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 PANTHER PTHR26402 4 114 6.2E-31 T 22-04-2016 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 SUPERFAMILY SSF52172 2 123 1.14E-28 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 SMART SM00850 138 229 1.5E-25 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 Gene3D G3DSA:2.40.50.40 133 198 5.8E-22 T 22-04-2016 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 Pfam PF00072 Response regulator receiver domain 7 112 2.4E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 PANTHER PTHR26402:SF524 4 114 6.2E-31 T 22-04-2016 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 Gene3D G3DSA:3.40.50.2300 3 122 3.3E-30 T 22-04-2016 MED134_RS05040 b1e8225afdd3f61dd60fb7dce002aea7 232 Pfam PF04397 LytTr DNA-binding domain 139 222 1.8E-19 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS09580 748213b1551a1d38b20925c0d0b360d5 214 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 45 195 3.4E-20 T 22-04-2016 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 Pfam PF08281 Sigma-70, region 4 124 174 1.3E-10 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 SUPERFAMILY SSF88659 106 183 6.73E-12 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 179 3.0E-25 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 PANTHER PTHR30173 1 184 2.9E-34 T 22-04-2016 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 SUPERFAMILY SSF88946 4 103 3.1E-22 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 Pfam PF04542 Sigma-70 region 2 27 93 1.9E-12 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 Gene3D G3DSA:1.10.10.10 122 182 5.1E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 PANTHER PTHR30173:SF24 1 184 2.9E-34 T 22-04-2016 MED134_RS04415 661dd526f87fcb4ea08c92c0db1a4e7d 192 Gene3D G3DSA:1.10.1740.10 6 111 1.6E-27 T 22-04-2016 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 SUPERFAMILY SSF82861 26 112 1.44E-11 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 Gene3D G3DSA:3.30.70.100 183 269 9.3E-16 T 22-04-2016 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 SUPERFAMILY SSF50182 115 179 2.68E-15 T 22-04-2016 IPR010920 LSM domain MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 PANTHER PTHR30221 18 292 1.2E-49 T 22-04-2016 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 Gene3D G3DSA:2.30.30.60 131 178 4.0E-14 T 22-04-2016 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 SUPERFAMILY SSF82689 182 283 2.48E-21 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 PANTHER PTHR30221:SF7 18 292 1.2E-49 T 22-04-2016 MED134_RS14280 b97b2882d24ef6e46eda0d4b44111ad2 292 Pfam PF00924 Mechanosensitive ion channel 70 272 1.5E-42 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 363 4.8E-100 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 Gene3D G3DSA:3.90.1150.10 250 366 1.6E-39 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 PIRSF PIRSF000390 1 367 2.9E-87 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 PANTHER PTHR30244:SF13 1 366 5.6E-110 T 22-04-2016 MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 PANTHER PTHR30244 1 366 5.6E-110 T 22-04-2016 MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 Gene3D G3DSA:3.40.640.10 14 248 2.6E-67 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS13610 127a9d9eb25e3e34337d15288c0ffd78 368 SUPERFAMILY SSF53383 13 366 1.1E-97 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 SUPERFAMILY SSF53056 4 208 1.83E-52 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 SMART SM00947 46 208 3.2E-44 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 PANTHER PTHR11002:SF22 10 207 7.0E-71 T 22-04-2016 MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 PANTHER PTHR11002 10 207 7.0E-71 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 Pfam PF00484 Carbonic anhydrase 54 205 2.5E-38 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MED134_RS09910 10fc831ba342206378c3aff6506c6f92 208 Gene3D G3DSA:3.40.1050.10 4 207 1.1E-54 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MED134_RS01180 c68e2d7a530d25c801358e57d9cef734 298 Gene3D G3DSA:3.40.710.10 50 274 1.0E-19 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01180 c68e2d7a530d25c801358e57d9cef734 298 Pfam PF13354 Beta-lactamase enzyme family 119 266 2.2E-14 T 22-04-2016 MED134_RS01180 c68e2d7a530d25c801358e57d9cef734 298 SUPERFAMILY SSF56601 73 277 3.87E-23 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 SUPERFAMILY SSF109604 462 676 6.28E-24 T 22-04-2016 MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 Pfam PF07697 7TM-HD extracellular 52 250 5.6E-9 T 22-04-2016 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 Pfam PF01966 HD domain 478 619 2.5E-17 T 22-04-2016 IPR006674 HD domain MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 Gene3D G3DSA:1.10.3210.10 464 675 3.6E-31 T 22-04-2016 IPR006674 HD domain MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 Pfam PF07698 7TM receptor with intracellular HD hydrolase 266 453 1.6E-37 T 22-04-2016 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 TIGRFAM TIGR00277 HDIG: HDIG domain 475 573 4.4E-25 T 22-04-2016 IPR006675 HDIG domain MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 PANTHER PTHR36442 41 682 1.4E-129 T 22-04-2016 MED134_RS01950 a3ca1f87857d139f28bc5d3ff8b74892 682 SMART SM00471 474 629 1.3E-10 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 Gene3D G3DSA:3.40.50.450 4 179 1.5E-64 T 22-04-2016 MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 PANTHER PTHR31223:SF0 5 191 4.7E-84 T 22-04-2016 MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 180 1.8E-58 T 22-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 PANTHER PTHR31223 5 191 4.7E-84 T 22-04-2016 MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 SUPERFAMILY SSF102405 3 181 1.83E-59 T 22-04-2016 MED134_RS05255 2ee3379f4aab1d982ab83d165165565b 198 Pfam PF03641 Possible lysine decarboxylase 48 178 4.0E-40 T 22-04-2016 IPR031100 LOG family MED134_RS04660 b3d618cea55cb4f1dfad0299436f5fa9 136 SUPERFAMILY SSF158682 4 132 3.14E-5 T 22-04-2016 IPR029024 TerB-like MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 PANTHER PTHR22642 23 543 7.7E-171 T 22-04-2016 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 PANTHER PTHR22642:SF2 23 543 7.7E-171 T 22-04-2016 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Gene3D G3DSA:2.30.40.10 20 82 8.8E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Gene3D G3DSA:2.30.40.10 512 543 8.8E-19 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 SUPERFAMILY SSF51556 80 141 1.17E-24 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 SUPERFAMILY SSF51556 215 501 1.17E-24 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Pfam PF07969 Amidohydrolase family 69 541 2.1E-89 T 22-04-2016 IPR013108 Amidohydrolase 3 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Gene3D G3DSA:3.20.20.140 83 103 1.9E-20 T 22-04-2016 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Gene3D G3DSA:3.20.20.140 217 482 1.9E-20 T 22-04-2016 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 SUPERFAMILY SSF51338 18 81 4.32E-22 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 SUPERFAMILY SSF51338 500 542 4.32E-22 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS13675 1188878db51fcf3b972a4da812e59b74 544 Gene3D G3DSA:2.30.40.10 483 511 3.8E-4 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 Gene3D G3DSA:3.40.710.10 229 589 9.6E-87 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS06245 e78b298f76228605599253e0f85a809c 622 Gene3D G3DSA:3.90.1310.10 110 228 2.8E-22 T 22-04-2016 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 SUPERFAMILY SSF56519 38 229 2.35E-41 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 Pfam PF00905 Penicillin binding protein transpeptidase domain 247 579 7.8E-54 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 2 588 4.4E-139 T 22-04-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 PANTHER PTHR30627:SF2 1 620 1.0E-139 T 22-04-2016 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 SUPERFAMILY SSF56601 230 589 2.82E-81 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS06245 e78b298f76228605599253e0f85a809c 622 PANTHER PTHR30627 1 620 1.0E-139 T 22-04-2016 MED134_RS06245 e78b298f76228605599253e0f85a809c 622 Pfam PF03717 Penicillin-binding Protein dimerisation domain 47 208 1.8E-32 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 Gene3D G3DSA:1.20.1290.10 7 116 7.9E-30 T 22-04-2016 IPR029032 AhpD-like MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 89 3.3E-10 T 22-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 SUPERFAMILY SSF69118 4 108 6.15E-26 T 22-04-2016 IPR029032 AhpD-like MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 PANTHER PTHR33930 8 114 5.7E-63 T 22-04-2016 MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 PANTHER PTHR33930:SF1 8 114 5.7E-63 T 22-04-2016 MED134_RS05005 c4caaca41d3193f5ff645ce1c686bc9c 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 105 1.4E-16 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 Gene3D G3DSA:3.40.50.300 27 192 9.0E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 PIRSF PIRSF002849 3 322 1.1E-131 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 PANTHER PTHR11603:SF149 9 322 1.3E-134 T 22-04-2016 MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 176 7.6E-64 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 PANTHER PTHR11603 9 322 1.3E-134 T 22-04-2016 MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 SUPERFAMILY SSF52540 15 293 2.59E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02795 765d7f391caa95216690f5a39d3026f5 322 Gene3D G3DSA:1.10.8.300 210 318 1.4E-35 T 22-04-2016 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 Pfam PF00023 Ankyrin repeat 103 131 0.019 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 PRINTS PR01415 Ankyrin repeat signature 35 50 7.0E-8 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 PRINTS PR01415 Ankyrin repeat signature 83 97 7.0E-8 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 PANTHER PTHR24198 5 153 1.6E-36 T 22-04-2016 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 Gene3D G3DSA:1.25.40.20 5 154 3.2E-40 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 SUPERFAMILY SSF48403 5 153 2.9E-40 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 Pfam PF12796 Ankyrin repeats (3 copies) 5 98 1.8E-14 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 SMART SM00248 67 96 7.0E-4 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 SMART SM00248 100 129 3.3 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 SMART SM00248 34 63 7.5E-4 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS08095 4fd08a1feb3b094f7129262e28bb2606 156 SMART SM00248 2 30 4000.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 PRINTS PR01249 Ribosomal protein L31 signature 45 60 3.7E-14 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 PRINTS PR01249 Ribosomal protein L31 signature 60 78 3.7E-14 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.7E-14 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 Pfam PF01197 Ribosomal protein L31 1 79 4.8E-26 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 7.9E-19 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 PANTHER PTHR33280 1 83 1.5E-27 T 22-04-2016 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 PANTHER PTHR33280:SF2 1 83 1.5E-27 T 22-04-2016 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS03460 f424b74312d5e7717bb86f92d1263d29 83 SUPERFAMILY SSF143800 1 80 2.98E-19 T 22-04-2016 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 Gene3D G3DSA:3.30.300.20 18 106 8.8E-32 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 36.453 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 Pfam PF07650 KH domain 37 110 9.5E-20 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 PANTHER PTHR11760:SF19 2 212 3.3E-120 T 22-04-2016 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 Gene3D G3DSA:3.30.1140.32 108 206 1.2E-42 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 SUPERFAMILY SSF54821 106 205 3.79E-38 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 PANTHER PTHR11760 2 212 3.3E-120 T 22-04-2016 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 22-04-2016 IPR018280 Ribosomal protein S3, conserved site MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.1E-86 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 8.8E-38 T 22-04-2016 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 SUPERFAMILY SSF54814 2 105 4.19E-35 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 MED134_RS12265 d7f8bc74d701ed3cd1117454161c16cb 239 SMART SM00322 59 124 1.2E-5 T 22-04-2016 IPR004087 K Homology domain GO:0003676 MED134_RS13545 0a1542439416619c70d97d1fabf63d25 2387 Pfam PF13585 C-terminal domain of CHU protein family 2296 2369 1.3E-10 T 22-04-2016 MED134_RS13545 0a1542439416619c70d97d1fabf63d25 2387 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 2295 2387 5.2E-35 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 259 28.598 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 Gene3D G3DSA:3.10.310.10 116 238 3.1E-30 T 22-04-2016 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 SUPERFAMILY SSF54506 3 118 9.03E-35 T 22-04-2016 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 PANTHER PTHR31689 1 258 5.6E-62 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 65 79 - T 22-04-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 Pfam PF01678 Diaminopimelate epimerase 133 251 8.5E-17 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 Pfam PF01678 Diaminopimelate epimerase 5 110 5.2E-22 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 SUPERFAMILY SSF54506 121 257 3.14E-30 T 22-04-2016 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 257 8.9E-62 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 MED134_RS03995 99d4800acf21b659debc76d9e1e780c1 259 Gene3D G3DSA:3.10.310.10 3 115 5.0E-34 T 22-04-2016 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 SUPERFAMILY SSF53613 5 311 1.54E-60 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 Pfam PF00294 pfkB family carbohydrate kinase 21 299 7.4E-46 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 PANTHER PTHR10584 162 300 7.4E-55 T 22-04-2016 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 PANTHER PTHR10584 1 142 7.4E-55 T 22-04-2016 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 PANTHER PTHR10584:SF188 162 300 7.4E-55 T 22-04-2016 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 PANTHER PTHR10584:SF188 1 142 7.4E-55 T 22-04-2016 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 26 50 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MED134_RS10585 3cb9527b10d2c32e6ac0e144a5a942d3 312 Gene3D G3DSA:3.40.1190.20 6 309 2.5E-68 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 22-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 PANTHER PTHR10681 3 166 3.9E-49 T 22-04-2016 MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 37.041 T 22-04-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 PANTHER PTHR10681:SF81 3 166 3.9E-49 T 22-04-2016 MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 Gene3D G3DSA:3.40.30.10 2 166 4.8E-50 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 Pfam PF08534 Redoxin 19 160 1.6E-27 T 22-04-2016 IPR013740 Redoxin GO:0016491 MED134_RS04170 cb44f893e59f80fd3a74be46670806fa 166 SUPERFAMILY SSF52833 1 162 1.2E-43 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 262 273 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 PANTHER PTHR11699 9 460 7.8E-193 T 22-04-2016 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 SUPERFAMILY SSF53720 9 460 7.46E-130 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 Gene3D G3DSA:3.40.605.10 9 249 3.6E-64 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 Pfam PF00171 Aldehyde dehydrogenase family 9 459 1.3E-127 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 Gene3D G3DSA:3.40.309.10 250 439 3.9E-53 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS01640 89e7c91fa4369c17d823903aebeb5171 465 PANTHER PTHR11699:SF28 9 460 7.8E-193 T 22-04-2016 MED134_RS11310 ff613de09b73eb2a1f4f83e628f78175 122 SUPERFAMILY SSF54593 8 119 2.75E-18 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS11310 ff613de09b73eb2a1f4f83e628f78175 122 Gene3D G3DSA:3.10.180.10 6 119 7.9E-19 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS05575 aa6ac22fef6d066ed672a88149affb52 666 SUPERFAMILY SSF54001 311 427 4.66E-8 T 22-04-2016 MED134_RS05575 aa6ac22fef6d066ed672a88149affb52 666 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 69 196 7.0E-9 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 MED134_RS05575 aa6ac22fef6d066ed672a88149affb52 666 Pfam PF01841 Transglutaminase-like superfamily 314 421 3.3E-5 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Gene3D G3DSA:3.30.930.10 179 408 1.5E-138 T 22-04-2016 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Gene3D G3DSA:3.30.930.10 10 93 1.5E-138 T 22-04-2016 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Pfam PF03129 Anticodon binding domain 413 502 4.5E-17 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 SUPERFAMILY SSF52954 400 504 2.27E-31 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 211 386 2.8E-8 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 5 505 45.926 T 22-04-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 9 292 1.2E-81 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PANTHER PTHR10745 9 115 2.1E-192 T 22-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PANTHER PTHR10745 143 505 2.1E-192 T 22-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 SUPERFAMILY SSF55681 9 116 3.32E-107 T 22-04-2016 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 SUPERFAMILY SSF55681 145 416 3.32E-107 T 22-04-2016 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 Gene3D G3DSA:3.40.50.800 409 504 6.6E-37 T 22-04-2016 IPR004154 Anticodon-binding MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 246 263 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 263 273 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 450 469 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 368 380 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 205 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS08055 ae30073f89ac35c6602ee7dde390395f 511 PRINTS PR01043 Glycyl-tRNA synthetase signature 214 231 1.6E-46 T 22-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 PANTHER PTHR31187 10 482 6.8E-23 T 22-04-2016 IPR004667 ADP/ATP carrier protein GO:0005471|GO:0005524|GO:0006810|GO:0016021 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 SUPERFAMILY SSF103473 18 414 1.7E-21 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 SUPERFAMILY SSF48371 427 768 5.47E-11 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 SUPERFAMILY SSF48371 830 867 5.47E-11 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 Gene3D G3DSA:1.20.1250.20 25 200 2.2E-9 T 22-04-2016 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 PANTHER PTHR31187:SF0 10 482 6.8E-23 T 22-04-2016 MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 Gene3D G3DSA:1.25.10.10 623 734 7.0E-7 T 22-04-2016 IPR011989 Armadillo-like helical MED134_RS01175 24e701c49160cbee61021845c6864ac2 947 Pfam PF03219 TLC ATP/ADP transporter 107 320 1.6E-11 T 22-04-2016 IPR004667 ADP/ATP carrier protein GO:0005471|GO:0005524|GO:0006810|GO:0016021 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Gene3D G3DSA:3.30.830.10 33 260 8.6E-55 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 SUPERFAMILY SSF63411 739 943 5.0E-43 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 SUPERFAMILY SSF63411 39 261 9.95E-54 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 SUPERFAMILY SSF63411 511 719 1.53E-46 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Gene3D G3DSA:3.30.830.10 516 730 5.1E-45 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Pfam PF05193 Peptidase M16 inactive domain 210 388 7.8E-30 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Pfam PF05193 Peptidase M16 inactive domain 681 857 3.3E-20 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 PANTHER PTHR11851 11 858 5.4E-187 T 22-04-2016 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 SUPERFAMILY SSF63411 266 458 1.43E-33 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 PANTHER PTHR11851:SF136 11 858 5.4E-187 T 22-04-2016 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Pfam PF00675 Insulinase (Peptidase family M16) 53 178 5.5E-17 T 22-04-2016 IPR011765 Peptidase M16, N-terminal MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Pfam PF00675 Insulinase (Peptidase family M16) 533 656 4.8E-15 T 22-04-2016 IPR011765 Peptidase M16, N-terminal MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Gene3D G3DSA:3.30.830.10 744 923 2.4E-26 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS00275 018b17fbc3caa40f05ab9568cfad8513 956 Gene3D G3DSA:3.30.830.10 290 447 3.3E-22 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS08400 757350b7a927b14a5f5ca976bf6e764c 191 Pfam PF10544 T5orf172 domain 3 74 1.2E-4 T 22-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 Pfam PF01546 Peptidase family M20/M25/M40 102 337 5.3E-6 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 SUPERFAMILY SSF55031 208 315 2.09E-19 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 40 411 3.5E-66 T 22-04-2016 IPR017439 Amidohydrolase GO:0016787 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 Gene3D G3DSA:3.40.630.10 316 455 2.9E-62 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 Gene3D G3DSA:3.40.630.10 19 207 2.9E-62 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 Pfam PF07687 Peptidase dimerisation domain 206 282 1.5E-6 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 SUPERFAMILY SSF53187 319 348 4.44E-58 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 SUPERFAMILY SSF53187 379 444 4.44E-58 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 SUPERFAMILY SSF53187 27 220 4.44E-58 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 Gene3D G3DSA:3.30.70.360 208 312 8.8E-20 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 PANTHER PTHR30575 126 350 4.2E-117 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 PANTHER PTHR30575 373 463 4.2E-117 T 22-04-2016 MED134_RS14050 2b3665b154ace407dc3993622e0dd913 477 PANTHER PTHR30575 17 109 4.2E-117 T 22-04-2016 MED134_RS14165 b4045d4d4fe01e21eccbef725ede7773 359 Gene3D G3DSA:3.40.50.2000 173 339 6.0E-19 T 22-04-2016 MED134_RS14165 b4045d4d4fe01e21eccbef725ede7773 359 SUPERFAMILY SSF53756 20 357 1.18E-54 T 22-04-2016 MED134_RS14165 b4045d4d4fe01e21eccbef725ede7773 359 PANTHER PTHR12526:SF374 66 357 6.3E-36 T 22-04-2016 MED134_RS14165 b4045d4d4fe01e21eccbef725ede7773 359 PANTHER PTHR12526 66 357 6.3E-36 T 22-04-2016 MED134_RS14165 b4045d4d4fe01e21eccbef725ede7773 359 Pfam PF00534 Glycosyl transferases group 1 179 326 1.6E-24 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 Gene3D G3DSA:3.40.309.10 306 499 6.5E-47 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 PANTHER PTHR11699 23 538 2.0E-257 T 22-04-2016 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 13 539 3.0E-238 T 22-04-2016 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|UniPathway: UPA00261 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 Gene3D G3DSA:3.40.605.10 41 305 1.3E-62 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 PANTHER PTHR11699:SF18 23 538 2.0E-257 T 22-04-2016 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 SUPERFAMILY SSF53720 9 526 6.94E-120 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS07070 10253fde3f7d3c3f9f98e4cf75b73680 543 Pfam PF00171 Aldehyde dehydrogenase family 56 513 1.2E-100 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS03325 5f8d139287804fcc3cb72ef36374fe89 216 SMART SM00464 5 188 0.0018 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 MED134_RS03325 5f8d139287804fcc3cb72ef36374fe89 216 SUPERFAMILY SSF88697 5 180 3.98E-25 T 22-04-2016 IPR015947 PUA-like domain MED134_RS09665 d27df2ae0357a4d6147c955baf5bfcb9 387 Gene3D G3DSA:1.20.1250.20 7 188 4.0E-18 T 22-04-2016 MED134_RS09665 d27df2ae0357a4d6147c955baf5bfcb9 387 Gene3D G3DSA:1.20.1250.20 201 362 3.1E-8 T 22-04-2016 MED134_RS09665 d27df2ae0357a4d6147c955baf5bfcb9 387 SUPERFAMILY SSF103473 4 383 1.7E-41 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS09665 d27df2ae0357a4d6147c955baf5bfcb9 387 Pfam PF07690 Major Facilitator Superfamily 12 352 2.0E-30 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS09665 d27df2ae0357a4d6147c955baf5bfcb9 387 PANTHER PTHR23501 7 354 3.0E-15 T 22-04-2016 MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 222 1.5E-13 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 Gene3D G3DSA:3.60.21.10 7 149 1.5E-28 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 Gene3D G3DSA:3.60.21.10 187 239 1.5E-28 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 SUPERFAMILY SSF56300 180 251 2.78E-29 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 SUPERFAMILY SSF56300 6 124 2.78E-29 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 PANTHER PTHR34990:SF2 2 235 1.5E-68 T 22-04-2016 MED134_RS03555 64b715098b595942ba0f1214ad9a566d 272 PANTHER PTHR34990 2 235 1.5E-68 T 22-04-2016 MED134_RS07195 1c5f269ddc516f05aa7e2d3874c1410e 847 Pfam PF13715 CarboxypepD_reg-like domain 24 107 7.0E-15 T 22-04-2016 MED134_RS07195 1c5f269ddc516f05aa7e2d3874c1410e 847 Gene3D G3DSA:2.60.40.1120 24 115 1.2E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07195 1c5f269ddc516f05aa7e2d3874c1410e 847 SUPERFAMILY SSF49464 22 105 1.96E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07195 1c5f269ddc516f05aa7e2d3874c1410e 847 PANTHER PTHR11532:SF57 5 107 5.2E-17 T 22-04-2016 MED134_RS07195 1c5f269ddc516f05aa7e2d3874c1410e 847 PANTHER PTHR11532 5 107 5.2E-17 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 PANTHER PTHR30069:SF4 109 880 1.4E-91 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Pfam PF13715 CarboxypepD_reg-like domain 27 101 3.0E-12 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Gene3D G3DSA:2.40.170.20 244 899 5.1E-72 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Gene3D G3DSA:2.170.130.10 122 243 8.3E-29 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Pfam PF07715 TonB-dependent Receptor Plug Domain 123 241 2.9E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 PANTHER PTHR30069 109 880 1.4E-91 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 SUPERFAMILY SSF49464 27 100 1.8E-12 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 SUPERFAMILY SSF56935 343 896 4.27E-82 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 SUPERFAMILY SSF56935 122 308 4.27E-82 T 22-04-2016 MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Gene3D G3DSA:2.60.40.1120 27 100 4.5E-13 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07895 b194b31737c6879d182a6c9306ab3c07 900 Pfam PF00593 TonB dependent receptor 578 897 7.8E-19 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10910 67fd3750f90e1f6a7635e4a0a589e9db 252 PANTHER PTHR30269:SF0 3 246 5.6E-32 T 22-04-2016 MED134_RS10910 67fd3750f90e1f6a7635e4a0a589e9db 252 PANTHER PTHR30269 3 246 5.6E-32 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 MED134_RS10910 67fd3750f90e1f6a7635e4a0a589e9db 252 Pfam PF01925 Sulfite exporter TauE/SafE 11 245 3.2E-30 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 MED134_RS09075 4b6763a884bee97fcc7d259775c8f3eb 257 SUPERFAMILY SSF56436 39 183 4.94E-11 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS09075 4b6763a884bee97fcc7d259775c8f3eb 257 Gene3D G3DSA:3.90.1580.10 45 183 8.8E-13 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS09075 4b6763a884bee97fcc7d259775c8f3eb 257 Pfam PF03781 Sulfatase-modifying factor enzyme 1 30 183 8.7E-10 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS05290 c2a9a2db6f18e6c1b5948b793f6a0650 154 Pfam PF14539 Domain of unknown function (DUF4442) 9 148 2.1E-13 T 22-04-2016 IPR027961 Protein of unknown function DUF4442 MED134_RS05290 c2a9a2db6f18e6c1b5948b793f6a0650 154 Gene3D G3DSA:3.10.129.10 6 153 1.9E-25 T 22-04-2016 IPR029069 HotDog domain MED134_RS05290 c2a9a2db6f18e6c1b5948b793f6a0650 154 SUPERFAMILY SSF54637 6 153 1.09E-18 T 22-04-2016 IPR029069 HotDog domain MED134_RS14445 2bf8cfbe3605618ca3693f6a56b54103 542 Pfam PF00144 Beta-lactamase 243 516 2.6E-13 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS14445 2bf8cfbe3605618ca3693f6a56b54103 542 PANTHER PTHR22935:SF80 137 535 1.1E-28 T 22-04-2016 MED134_RS14445 2bf8cfbe3605618ca3693f6a56b54103 542 SUPERFAMILY SSF56601 221 537 1.19E-56 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS14445 2bf8cfbe3605618ca3693f6a56b54103 542 Gene3D G3DSA:3.40.710.10 226 525 8.3E-31 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS14445 2bf8cfbe3605618ca3693f6a56b54103 542 PANTHER PTHR22935 137 535 1.1E-28 T 22-04-2016 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 PANTHER PTHR11071 12 235 9.1E-25 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 PANTHER PTHR11071:SF78 12 235 9.1E-25 T 22-04-2016 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 Gene3D G3DSA:2.40.100.10 71 235 1.7E-40 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 199 214 1.7E-8 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 120 132 1.7E-8 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 82 234 4.3E-37 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS00135 909beb656b01e1c605dae7fb12f045a8 240 SUPERFAMILY SSF50891 72 235 2.78E-38 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS04510 ca0836faae97def965dd2f9ba11fcd61 437 SUPERFAMILY SSF55920 186 405 1.57E-13 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS04510 ca0836faae97def965dd2f9ba11fcd61 437 Pfam PF00557 Metallopeptidase family M24 198 408 4.0E-8 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS04510 ca0836faae97def965dd2f9ba11fcd61 437 Gene3D G3DSA:3.90.230.10 186 429 2.8E-12 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 SUPERFAMILY SSF53474 100 274 2.5E-42 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 SUPERFAMILY SSF53474 363 453 2.5E-42 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 223 253 - T 22-04-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 PANTHER PTHR12277 371 455 2.1E-15 T 22-04-2016 MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 PANTHER PTHR12277 130 275 2.1E-15 T 22-04-2016 MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 Gene3D G3DSA:3.40.50.1820 127 305 3.0E-79 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 Gene3D G3DSA:3.40.50.1820 340 453 3.0E-79 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00295 76674f708a77d5a3c0473aa72a73fa9b 455 Pfam PF12146 Serine aminopeptidase, S33 183 417 1.3E-14 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 SUPERFAMILY SSF52141 2 221 2.83E-89 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 22-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 PANTHER PTHR11264 1 221 3.5E-126 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 SMART SM00986 50 211 6.2E-37 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 2.7E-21 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 37.287 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 Gene3D G3DSA:3.40.470.10 3 221 5.0E-94 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 SMART SM00987 50 211 6.2E-37 T 22-04-2016 MED134_RS02705 ad06568b34a1f66990bab44fd641d332 221 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 2.0E-80 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 105 1.6E-18 T 22-04-2016 IPR000361 FeS cluster biogenesis MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 108 1.6E-33 T 22-04-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 90 107 - T 22-04-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 Gene3D G3DSA:2.60.300.12 1 98 1.2E-29 T 22-04-2016 IPR000361 FeS cluster biogenesis MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 SUPERFAMILY SSF89360 1 98 3.14E-25 T 22-04-2016 IPR000361 FeS cluster biogenesis MED134_RS10895 7740fec5958f619f8129d28ccc9656c3 109 PANTHER PTHR10072 1 108 1.4E-38 T 22-04-2016 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 PANTHER PTHR30456 1 234 3.7E-103 T 22-04-2016 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 237 86.01 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 PANTHER PTHR30456:SF0 1 234 3.7E-103 T 22-04-2016 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 3 236 4.7E-82 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 234 8.0E-90 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 Gene3D G3DSA:3.20.20.70 1 236 8.7E-90 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS07505 15b59de33e494e9bb407ba014638c326 237 SUPERFAMILY SSF63892 1 236 7.72E-87 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 SUPERFAMILY SSF55048 125 186 3.79E-18 T 22-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 Gene3D G3DSA:3.40.366.10 3 117 1.3E-71 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 Gene3D G3DSA:3.40.366.10 190 285 1.3E-71 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 SUPERFAMILY SSF52151 183 288 1.02E-72 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 SUPERFAMILY SSF52151 2 117 1.02E-72 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 291 2.9E-43 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 PANTHER PTHR10982 1 287 6.2E-134 T 22-04-2016 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 Pfam PF00698 Acyl transferase domain 4 281 5.4E-42 T 22-04-2016 IPR014043 Acyl transferase MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 PIRSF PIRSF000446 1 292 8.3E-97 T 22-04-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 Gene3D G3DSA:3.30.70.250 120 189 1.0E-26 T 22-04-2016 MED134_RS07275 85b2c6ed1d1e51cafda34eefdef1920d 294 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 2 284 2.0E-100 T 22-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 PANTHER PTHR11730 7 426 3.7E-157 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 Pfam PF00909 Ammonium Transporter Family 30 418 3.3E-118 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 ProSitePatterns PS01219 Ammonium transporters signature. 167 192 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 TIGRFAM TIGR00836 amt: ammonium transporter 29 418 9.8E-122 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 SUPERFAMILY SSF111352 27 399 1.44E-109 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 PANTHER PTHR11730:SF6 7 426 3.7E-157 T 22-04-2016 MED134_RS13695 1078d0f6fbc2827855f514661b8b600a 426 Gene3D G3DSA:1.10.3430.10 29 399 3.0E-118 T 22-04-2016 IPR029020 Ammonium/urea transporter MED134_RS14045 f89f85a282ea24cd6c42943876e208fd 164 SUPERFAMILY SSF54593 40 161 2.69E-23 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS14045 f89f85a282ea24cd6c42943876e208fd 164 Gene3D G3DSA:3.10.180.10 39 160 3.3E-22 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS14045 f89f85a282ea24cd6c42943876e208fd 164 PANTHER PTHR10374 27 158 8.4E-12 T 22-04-2016 MED134_RS14045 f89f85a282ea24cd6c42943876e208fd 164 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 41 158 6.3E-12 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 Gene3D G3DSA:3.90.1150.10 319 396 8.0E-30 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 Gene3D G3DSA:3.90.1150.10 429 459 8.0E-30 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 PANTHER PTHR11601:SF24 14 495 2.6E-149 T 22-04-2016 MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 SUPERFAMILY SSF53383 32 459 9.15E-73 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 Gene3D G3DSA:3.40.640.10 55 318 5.2E-58 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 PANTHER PTHR11601 14 495 2.6E-149 T 22-04-2016 MED134_RS01220 1e4e913912f9da2ada39d3cdf4fcebb9 501 Pfam PF00266 Aminotransferase class-V 47 451 1.2E-40 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 PANTHER PTHR32060 83 351 2.3E-13 T 22-04-2016 MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 SUPERFAMILY SSF52096 158 412 2.49E-35 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 Pfam PF03572 Peptidase family S41 214 352 8.7E-18 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 Gene3D G3DSA:3.90.226.10 198 432 5.2E-37 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 Gene3D G3DSA:2.30.42.10 118 150 3.1E-4 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS03220 7500930efdecdda66a26d0611b4a3fcd 468 SUPERFAMILY SSF50156 101 151 1.48E-5 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 PANTHER PTHR11759 19 127 2.8E-55 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 124 5.4E-54 T 22-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 SUPERFAMILY SSF53137 16 127 7.19E-45 T 22-04-2016 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 Pfam PF00411 Ribosomal protein S11 17 126 1.0E-44 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 31.509 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 Gene3D G3DSA:3.30.420.80 4 127 1.4E-49 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 22-04-2016 IPR018102 Ribosomal S11, conserved site MED134_RS12350 705e8bfa526ed39e9662a0fff57152e8 127 PIRSF PIRSF002131 1 127 1.5E-49 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 Gene3D G3DSA:3.30.70.360 201 368 2.3E-61 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10445 d1c143137c75617680c4643312e529a4 462 PANTHER PTHR11014:SF72 288 462 1.7E-185 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 PANTHER PTHR11014:SF72 1 270 1.7E-185 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 Gene3D G3DSA:3.40.630.10 3 195 2.8E-61 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 Gene3D G3DSA:3.40.630.10 371 458 2.8E-61 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 PANTHER PTHR11014 288 462 1.7E-185 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 PANTHER PTHR11014 1 270 1.7E-185 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 SUPERFAMILY SSF55031 304 367 6.93E-6 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10445 d1c143137c75617680c4643312e529a4 462 SUPERFAMILY SSF55031 201 247 6.93E-6 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10445 d1c143137c75617680c4643312e529a4 462 SUPERFAMILY SSF53187 372 456 5.53E-62 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 SUPERFAMILY SSF53187 2 201 5.53E-62 T 22-04-2016 MED134_RS10445 d1c143137c75617680c4643312e529a4 462 Pfam PF07687 Peptidase dimerisation domain 199 358 1.7E-26 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS10445 d1c143137c75617680c4643312e529a4 462 Pfam PF01546 Peptidase family M20/M25/M40 82 450 1.7E-32 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 SUPERFAMILY SSF54373 350 505 1.45E-49 T 22-04-2016 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 PANTHER PTHR11552 222 566 3.9E-53 T 22-04-2016 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 PANTHER PTHR11552 1 206 3.9E-53 T 22-04-2016 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 SUPERFAMILY SSF51905 504 565 1.94E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 SUPERFAMILY SSF51905 102 345 1.94E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 SUPERFAMILY SSF51905 7 69 1.94E-62 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 Pfam PF05199 GMC oxidoreductase 433 556 3.1E-22 T 22-04-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 PANTHER PTHR11552:SF139 222 566 3.9E-53 T 22-04-2016 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 PANTHER PTHR11552:SF139 1 206 3.9E-53 T 22-04-2016 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 Gene3D G3DSA:3.50.50.60 234 342 3.3E-77 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 Gene3D G3DSA:3.50.50.60 464 562 3.3E-77 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 Gene3D G3DSA:3.50.50.60 9 162 3.3E-77 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09575 ad94fec088b5cd0d96a1cdce353122e6 568 Pfam PF00732 GMC oxidoreductase 103 340 2.8E-11 T 22-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 Pfam PF01546 Peptidase family M20/M25/M40 95 494 1.9E-21 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 Pfam PF07687 Peptidase dimerisation domain 230 381 1.9E-14 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014:SF72 326 381 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014:SF72 399 496 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014:SF72 19 119 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014:SF72 141 291 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 SUPERFAMILY SSF53187 22 231 6.0E-42 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 SUPERFAMILY SSF53187 413 495 6.0E-42 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 Gene3D G3DSA:3.40.630.10 412 496 1.1E-44 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 Gene3D G3DSA:3.40.630.10 23 225 1.1E-44 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014 326 381 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014 399 496 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014 19 119 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 PANTHER PTHR11014 141 291 1.3E-58 T 22-04-2016 MED134_RS08120 45b676f9c5efc7d4cf2f273631f1721c 499 Gene3D G3DSA:3.30.70.360 231 382 1.8E-38 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS04135 4d567443975d8ece560ed628672f93d2 212 Pfam PF02517 CAAX protease self-immunity 103 191 2.1E-10 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 PRINTS PR01100 Shikimate kinase family signature 102 119 3.2E-6 T 22-04-2016 MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 PRINTS PR01100 Shikimate kinase family signature 5 20 3.2E-6 T 22-04-2016 MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 Gene3D G3DSA:3.40.50.300 2 165 8.9E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 Pfam PF01202 Shikimate kinase 11 135 1.7E-15 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 SUPERFAMILY SSF52540 4 164 1.35E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 5 162 7.2E-50 T 22-04-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 MED134_RS02815 955b73f7e48b97c192641d5e073ef1ec 166 PANTHER PTHR11603 3 166 5.8E-71 T 22-04-2016 MED134_RS02895 4a46d7a79522ce872e6856db600754d3 264 SMART SM00850 162 260 2.9E-13 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS02895 4a46d7a79522ce872e6856db600754d3 264 Pfam PF04397 LytTr DNA-binding domain 170 259 1.5E-14 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS02895 4a46d7a79522ce872e6856db600754d3 264 Gene3D G3DSA:2.40.50.40 161 222 7.5E-9 T 22-04-2016 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 218 307 1.3E-33 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 52 69 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 SUPERFAMILY SSF54534 184 310 1.75E-47 T 22-04-2016 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 Gene3D G3DSA:2.40.100.10 6 159 4.6E-54 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PANTHER PTHR11071 9 145 5.2E-62 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 SUPERFAMILY SSF50891 7 151 7.16E-53 T 22-04-2016 IPR029000 Cyclophilin-like domain MED134_RS03930 c5e09520a4152558792eb1118377648a 310 Gene3D G3DSA:3.10.50.40 176 310 4.2E-52 T 22-04-2016 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 156 2.9E-43 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 97 112 7.0E-32 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 57 69 7.0E-32 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 125 140 7.0E-32 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 124 7.0E-32 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS03930 c5e09520a4152558792eb1118377648a 310 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 7.0E-32 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MED134_RS13475 30cf770327254527e76ca3573e1db99b 338 PANTHER PTHR12526 25 337 9.7E-25 T 22-04-2016 MED134_RS13475 30cf770327254527e76ca3573e1db99b 338 Gene3D G3DSA:3.40.50.2000 179 317 1.9E-12 T 22-04-2016 MED134_RS13475 30cf770327254527e76ca3573e1db99b 338 Pfam PF13692 Glycosyl transferases group 1 165 306 5.5E-19 T 22-04-2016 MED134_RS13475 30cf770327254527e76ca3573e1db99b 338 SUPERFAMILY SSF53756 22 337 7.33E-44 T 22-04-2016 MED134_RS00790 c20c4bc3b8fe2333452e7cfaa037641a 667 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 510 654 1.1E-19 T 22-04-2016 MED134_RS00790 c20c4bc3b8fe2333452e7cfaa037641a 667 SUPERFAMILY SSF49899 451 659 1.37E-29 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS00790 c20c4bc3b8fe2333452e7cfaa037641a 667 SMART SM00560 519 651 6.9E-4 T 22-04-2016 IPR006558 LamG-like jellyroll fold MED134_RS00790 c20c4bc3b8fe2333452e7cfaa037641a 667 Gene3D G3DSA:2.60.120.200 457 658 6.8E-28 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS06095 83c12a146a262dd050bfba3dea4993ec 211 TIGRFAM TIGR03513 GldL_gliding: gliding motility-associated protein GldL 8 208 9.4E-74 T 22-04-2016 IPR019852 Gliding motility-associated protein, GldL MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 PANTHER PTHR34069:SF2 1 352 1.0E-63 T 22-04-2016 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 253 352 7.2E-15 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 Gene3D G3DSA:3.40.47.10 1 184 2.1E-43 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 SUPERFAMILY SSF53901 3 352 1.93E-46 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 PANTHER PTHR34069 1 352 1.0E-63 T 22-04-2016 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 129 202 4.4E-17 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 MED134_RS11960 aebc11e8269512cee260e91fe9087f0a 352 Gene3D G3DSA:3.40.47.10 185 351 9.2E-34 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS04860 92fa3e527d5f4f71c69982ea8e303096 135 SUPERFAMILY SSF52172 5 131 9.39E-29 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS04860 92fa3e527d5f4f71c69982ea8e303096 135 SMART SM00448 3 123 4.2E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04860 92fa3e527d5f4f71c69982ea8e303096 135 PANTHER PTHR26402 8 123 7.0E-26 T 22-04-2016 MED134_RS04860 92fa3e527d5f4f71c69982ea8e303096 135 Pfam PF00072 Response regulator receiver domain 5 123 4.4E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04860 92fa3e527d5f4f71c69982ea8e303096 135 Gene3D G3DSA:3.40.50.2300 5 123 1.7E-29 T 22-04-2016 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 Gene3D G3DSA:3.90.226.10 19 283 2.3E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PANTHER PTHR22855:SF17 1 282 1.0E-116 T 22-04-2016 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 2 279 9.5E-100 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 SUPERFAMILY SSF52096 32 283 2.81E-72 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 280 35.031 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 142 2.0E-34 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 162 180 2.0E-34 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 250 259 2.0E-34 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 216 2.0E-34 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 228 239 2.0E-34 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 Pfam PF01039 Carboxyl transferase domain 99 241 4.5E-18 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 MED134_RS05515 23fa24130142a5e9526387db1a0beb78 285 PANTHER PTHR22855 1 282 1.0E-116 T 22-04-2016 MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 Pfam PF07495 Y_Y_Y domain 652 713 9.0E-12 T 22-04-2016 IPR011123 Two component regulator three Y MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 Gene3D G3DSA:2.130.10.10 249 439 5.7E-8 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 Gene3D G3DSA:2.130.10.10 477 583 5.7E-8 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 SUPERFAMILY SSF69304 322 519 4.32E-5 T 22-04-2016 MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 SUPERFAMILY SSF46894 854 918 3.4E-10 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 Gene3D G3DSA:1.10.10.10 862 919 1.0E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS09430 beb34bd10e90670dc7bbe4de69900235 920 SMART SM00421 860 917 0.0052 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS10935 50cdffd267750727ed96d3ccd82fce0c 482 SUPERFAMILY SSF50998 251 463 2.12E-6 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MED134_RS10935 50cdffd267750727ed96d3ccd82fce0c 482 PANTHER PTHR32438 72 209 2.3E-22 T 22-04-2016 MED134_RS10935 50cdffd267750727ed96d3ccd82fce0c 482 PANTHER PTHR32438 233 434 2.3E-22 T 22-04-2016 MED134_RS10935 50cdffd267750727ed96d3ccd82fce0c 482 PANTHER PTHR32438:SF6 72 209 2.3E-22 T 22-04-2016 MED134_RS10935 50cdffd267750727ed96d3ccd82fce0c 482 PANTHER PTHR32438:SF6 233 434 2.3E-22 T 22-04-2016 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 Hamap MF_00323 Ferrochelatase [hemH]. 1 337 34.181 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 Gene3D G3DSA:3.40.50.1400 195 335 8.7E-31 T 22-04-2016 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 PANTHER PTHR11108 224 335 8.7E-90 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 PANTHER PTHR11108 4 201 8.7E-90 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 SUPERFAMILY SSF53800 3 337 3.14E-90 T 22-04-2016 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 TIGRFAM TIGR00109 hemH: ferrochelatase 3 212 7.4E-46 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 Pfam PF00762 Ferrochelatase 3 335 1.7E-99 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 MED134_RS08655 2e165155ce56b66bf74df08c8f6500b7 346 Gene3D G3DSA:3.40.50.1400 2 194 9.1E-54 T 22-04-2016 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 377 600 1.9E-30 T 22-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 PANTHER PTHR11731 267 331 2.3E-31 T 22-04-2016 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 PANTHER PTHR11731 28 209 2.3E-31 T 22-04-2016 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 SUPERFAMILY SSF49785 395 617 5.74E-50 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 SMART SM00939 361 619 2.9E-62 T 22-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 SUPERFAMILY SSF53474 28 398 7.47E-61 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Gene3D G3DSA:3.40.50.1820 275 391 1.4E-80 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Gene3D G3DSA:3.40.50.1820 11 198 1.4E-80 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 47 617 1.7E-75 T 22-04-2016 IPR005674 CocE/Serine esterase GO:0016787 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 PANTHER PTHR11731:SF151 267 331 2.3E-31 T 22-04-2016 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 PANTHER PTHR11731:SF151 28 209 2.3E-31 T 22-04-2016 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 50 331 1.2E-51 T 22-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Gene3D G3DSA:2.60.120.260 392 621 1.5E-73 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS04785 ee54d2ee5bd10cab872a33ba25c7de26 625 Gene3D G3DSA:1.10.3020.10 199 274 4.4E-27 T 22-04-2016 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 SUPERFAMILY SSF88659 101 168 3.05E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 PANTHER PTHR30173 11 170 8.1E-31 T 22-04-2016 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 Pfam PF04542 Sigma-70 region 2 19 82 3.0E-9 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 PANTHER PTHR30173:SF20 11 170 8.1E-31 T 22-04-2016 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 SUPERFAMILY SSF88946 13 85 5.1E-13 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 Pfam PF08281 Sigma-70, region 4 113 164 3.0E-16 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 Gene3D G3DSA:1.10.10.10 107 170 5.4E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 167 5.3E-24 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00785 be229c287db1bc72fd27fbd1a000b11d 172 Gene3D G3DSA:1.10.1740.10 14 106 3.4E-13 T 22-04-2016 MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 SUPERFAMILY SSF51735 419 548 1.25E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 PANTHER PTHR16254:SF6 5 574 8.5E-186 T 22-04-2016 MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 PANTHER PTHR16254 5 574 8.5E-186 T 22-04-2016 MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 Gene3D G3DSA:3.40.50.720 415 548 1.5E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 Pfam PF00999 Sodium/hydrogen exchanger family 11 390 5.7E-60 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MED134_RS00550 7f23c50569d28a1c25535387d6acb2df 617 Pfam PF02254 TrkA-N domain 420 533 2.3E-22 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MED134_RS09540 92857e2170c647af23eb736862aee07b 253 PANTHER PTHR33546:SF1 78 253 3.0E-19 T 22-04-2016 MED134_RS09540 92857e2170c647af23eb736862aee07b 253 PANTHER PTHR33546 78 253 3.0E-19 T 22-04-2016 MED134_RS09540 92857e2170c647af23eb736862aee07b 253 Pfam PF06439 Domain of Unknown Function (DUF1080) 55 250 7.9E-40 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 MED134_RS10000 9cc2458b81065283f88c700098c31281 129 Pfam PF01230 HIT domain 11 100 2.1E-18 T 22-04-2016 IPR001310 Histidine triad (HIT) protein MED134_RS10000 9cc2458b81065283f88c700098c31281 129 Gene3D G3DSA:3.30.428.10 2 129 4.2E-29 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 MED134_RS10000 9cc2458b81065283f88c700098c31281 129 PRINTS PR00332 Histidine triad family signature 4 20 1.4E-14 T 22-04-2016 IPR001310 Histidine triad (HIT) protein MED134_RS10000 9cc2458b81065283f88c700098c31281 129 PRINTS PR00332 Histidine triad family signature 25 43 1.4E-14 T 22-04-2016 IPR001310 Histidine triad (HIT) protein MED134_RS10000 9cc2458b81065283f88c700098c31281 129 PRINTS PR00332 Histidine triad family signature 87 97 1.4E-14 T 22-04-2016 IPR001310 Histidine triad (HIT) protein MED134_RS10000 9cc2458b81065283f88c700098c31281 129 SUPERFAMILY SSF54197 3 129 5.88E-34 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 MED134_RS10000 9cc2458b81065283f88c700098c31281 129 PANTHER PTHR23089 4 104 1.2E-29 T 22-04-2016 IPR001310 Histidine triad (HIT) protein MED134_RS14110 c16c436d85e9f8cff6d8c97e1946e136 171 SUPERFAMILY SSF159941 1 171 2.09E-43 T 22-04-2016 IPR024047 Protein MM3350-like domain MED134_RS14110 c16c436d85e9f8cff6d8c97e1946e136 171 Gene3D G3DSA:3.10.290.30 1 168 1.1E-36 T 22-04-2016 IPR024047 Protein MM3350-like domain MED134_RS14110 c16c436d85e9f8cff6d8c97e1946e136 171 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 3 131 7.6E-18 T 22-04-2016 IPR012912 Plasmid pRiA4b, Orf3 MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 3921 4024 6.1E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF02494 HYR domain 25 106 4.5E-8 T 22-04-2016 IPR003410 HYR domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF02494 HYR domain 3621 3675 1.7E-5 T 22-04-2016 IPR003410 HYR domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF02494 HYR domain 3233 3269 1.5E-4 T 22-04-2016 IPR003410 HYR domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF02494 HYR domain 375 433 1.7E-6 T 22-04-2016 IPR003410 HYR domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF00754 F5/8 type C domain 3100 3195 1.0E-6 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF00754 F5/8 type C domain 3471 3599 1.8E-7 T 22-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 665 771 1.61E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 3476 3606 1.8E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 1031 1176 4.6E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 1839 1986 7.0E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 2288 2393 2.9E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 256 365 3.7E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 659 770 5.0E-8 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 1436 1582 3.3E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 3099 3202 1.7E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 3458 3606 2.1E-10 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.120.260 2693 2796 2.4E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 2276 2393 9.04E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Pfam PF01483 Proprotein convertase P-domain 3921 4023 1.7E-12 T 22-04-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 Gene3D G3DSA:2.60.40.920 2905 2971 6.9E-4 T 22-04-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 3914 4024 2.21E-12 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 1072 1177 1.51E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 3102 3194 1.61E-9 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 2694 2796 1.04E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 266 358 7.75E-7 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 1886 1986 1.03E-6 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 4265 4330 1.4E-7 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS12965 4896401d98b930f4622a7d68e7428e03 4332 SUPERFAMILY SSF49785 1477 1583 1.13E-5 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Gene3D G3DSA:3.40.50.970 377 571 1.1E-67 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 183 4.7E-58 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 PANTHER PTHR18968 1 574 2.0E-270 T 22-04-2016 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 SUPERFAMILY SSF52467 200 361 8.28E-55 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS04735 afd85950e20b512942a800133ca71b64 574 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 22-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 341 4.2E-41 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 PANTHER PTHR18968:SF116 1 574 2.0E-270 T 22-04-2016 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Gene3D G3DSA:3.40.50.970 14 188 2.5E-71 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 550 3.6E-45 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 SUPERFAMILY SSF52518 9 198 3.61E-63 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS04735 afd85950e20b512942a800133ca71b64 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 16 571 7.2E-214 T 22-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04735 afd85950e20b512942a800133ca71b64 574 SUPERFAMILY SSF52518 380 571 2.4E-63 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS04735 afd85950e20b512942a800133ca71b64 574 Gene3D G3DSA:3.40.50.1220 202 362 7.0E-57 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 PANTHER PTHR38478 1 763 3.2E-159 T 22-04-2016 MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 Pfam PF16313 Met-zincin 428 735 1.2E-125 T 22-04-2016 IPR032534 Domian of unknown function DUF4953 MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 SUPERFAMILY SSF55486 299 519 5.87E-24 T 22-04-2016 MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 Pfam PF17148 Domain of unknown function (DUF5117) 102 293 1.0E-57 T 22-04-2016 IPR033413 Domain of unknown function DUF5117 MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 Pfam PF17162 Domain of unknown function (DUF5118) 46 94 5.8E-24 T 22-04-2016 IPR033428 Domain of unknown function DUF5118 MED134_RS11610 dc6b28332995d8e52e21d00e502e7d48 825 Gene3D G3DSA:3.40.390.10 269 520 1.9E-20 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 PANTHER PTHR23132 17 341 2.0E-74 T 22-04-2016 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 287 314 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Pfam PF01820 D-ala D-ala ligase N-terminus 22 124 4.5E-22 T 22-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 101 112 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 23 342 6.4E-77 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 PIRSF PIRSF039102 18 348 3.2E-86 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 21 344 31.474 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Gene3D G3DSA:3.40.50.20 19 122 4.2E-25 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Gene3D G3DSA:3.30.1490.20 145 216 4.1E-22 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 SUPERFAMILY SSF52440 20 133 9.02E-30 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Gene3D G3DSA:3.30.470.20 125 141 1.1E-36 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Gene3D G3DSA:3.30.470.20 217 342 1.1E-36 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 Pfam PF07478 D-ala D-ala ligase C-terminus 142 336 9.7E-47 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 PANTHER PTHR23132:SF0 17 341 2.0E-74 T 22-04-2016 MED134_RS13005 93652c4f12c4ce70b2ba01fff44e8f26 348 SUPERFAMILY SSF56059 134 340 1.22E-47 T 22-04-2016 MED134_RS04570 2957230579db9fe2fec518d3e102db62 148 Pfam PF05751 FixH 4 146 2.2E-21 T 22-04-2016 IPR008620 Nitrogen fixation protein FixH MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 SUPERFAMILY SSF82171 22 475 2.88E-69 T 22-04-2016 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 Gene3D G3DSA:2.140.10.30 21 474 3.6E-118 T 22-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 PANTHER PTHR11731:SF110 21 729 5.1E-220 T 22-04-2016 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 574 604 - T 22-04-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 Gene3D G3DSA:3.40.50.1820 480 729 1.2E-83 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 SUPERFAMILY SSF53474 480 729 1.94E-74 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 Pfam PF00326 Prolyl oligopeptidase family 534 729 1.0E-56 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 99 445 3.6E-97 T 22-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MED134_RS06465 b4154cd84d059dc7f1f1b7a64d19420e 729 PANTHER PTHR11731 21 729 5.1E-220 T 22-04-2016 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 PANTHER PTHR31964 1 164 5.2E-15 T 22-04-2016 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 SUPERFAMILY SSF52402 3 148 6.03E-23 T 22-04-2016 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 Pfam PF00582 Universal stress protein family 3 146 5.2E-13 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 PANTHER PTHR31964:SF26 1 164 5.2E-15 T 22-04-2016 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 Gene3D G3DSA:3.40.50.620 194 279 3.4E-4 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 Gene3D G3DSA:3.40.50.620 3 148 3.2E-21 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 SUPERFAMILY SSF52402 155 279 1.84E-10 T 22-04-2016 MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 PRINTS PR01438 Universal stress protein signature 105 117 1.1E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 PRINTS PR01438 Universal stress protein signature 1 18 1.1E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04630 240417d0be753ed69335148ffa6d58fc 281 PRINTS PR01438 Universal stress protein signature 123 145 1.1E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 SUPERFAMILY SSF53067 149 313 2.72E-10 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 SUPERFAMILY SSF53067 8 34 2.72E-10 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 SUPERFAMILY SSF53067 76 119 2.72E-10 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 Gene3D G3DSA:3.30.420.40 6 198 1.3E-55 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 PANTHER PTHR30605 1 366 7.6E-102 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 PANTHER PTHR30605:SF0 1 366 7.6E-102 T 22-04-2016 MED134_RS06405 be7063e59a799438fd130fc7ae3d22ee 368 Pfam PF03702 Uncharacterised protein family (UPF0075) 8 366 3.1E-72 T 22-04-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 Hamap MF_01398 ATP synthase subunit b [atpF]. 8 165 12.98 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 PANTHER PTHR33445 7 166 2.6E-36 T 22-04-2016 MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 SUPERFAMILY SSF81573 68 127 1.44E-9 T 22-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 Pfam PF00430 ATP synthase B/B' CF(0) 13 142 3.4E-30 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 16 162 2.8E-36 T 22-04-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 MED134_RS09410 b673861078ac054800b62d3b1efb5be6 166 Gene3D G3DSA:1.20.5.620 68 127 1.9E-14 T 22-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain MED134_RS13595 0dc1cbfbdf6735f8145538f6207e061f 381 PANTHER PTHR10859:SF57 4 337 1.9E-63 T 22-04-2016 MED134_RS13595 0dc1cbfbdf6735f8145538f6207e061f 381 SUPERFAMILY SSF53448 4 235 4.03E-31 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13595 0dc1cbfbdf6735f8145538f6207e061f 381 PANTHER PTHR10859 4 337 1.9E-63 T 22-04-2016 MED134_RS13595 0dc1cbfbdf6735f8145538f6207e061f 381 Pfam PF00535 Glycosyl transferase family 2 6 165 2.1E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13595 0dc1cbfbdf6735f8145538f6207e061f 381 Gene3D G3DSA:3.90.550.10 4 120 6.3E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 71 23.931 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 PANTHER PTHR33370 1 71 6.0E-45 T 22-04-2016 MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.7E-25 T 22-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 SUPERFAMILY SSF50249 1 71 3.0E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.8E-35 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MED134_RS12340 754141fbf9237bbf64774cbc0ec45c17 71 Gene3D G3DSA:2.40.50.140 1 71 5.7E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS13570 862258edbf9ca71c56f55af07f962166 184 SUPERFAMILY SSF54534 53 180 4.12E-20 T 22-04-2016 MED134_RS13570 862258edbf9ca71c56f55af07f962166 184 TIGRFAM TIGR03516 ppisom_GldI: peptidyl-prolyl isomerase, gliding motility-associated 1 179 2.4E-65 T 22-04-2016 IPR019869 Gliding motility-associated, peptidyl-prolyl isomerase, GldI MED134_RS13570 862258edbf9ca71c56f55af07f962166 184 Gene3D G3DSA:3.10.50.40 44 182 4.0E-23 T 22-04-2016 MED134_RS13570 862258edbf9ca71c56f55af07f962166 184 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 86 175 5.1E-9 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 Gene3D G3DSA:3.40.50.1820 49 314 4.8E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 PANTHER PTHR10794:SF46 1 322 7.4E-45 T 22-04-2016 MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 PIRSF PIRSF005211 1 322 1.4E-82 T 22-04-2016 IPR012020 AB hydrolase 4 family KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 PANTHER PTHR10794 1 322 7.4E-45 T 22-04-2016 MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 227 268 - T 22-04-2016 IPR000952 AB hydrolase 4, conserved site KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 Pfam PF12146 Serine aminopeptidase, S33 61 270 2.5E-9 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS09750 a30e2b8f5e2bd14bc53f281857a75a02 322 SUPERFAMILY SSF53474 29 311 6.93E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 24 279 2.2E-75 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 SUPERFAMILY SSF53335 19 283 7.17E-72 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 24 282 47.502 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 Gene3D G3DSA:3.40.50.150 19 217 2.9E-63 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 SMART SM00650 40 216 3.2E-53 T 22-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 Pfam PF00398 Ribosomal RNA adenine dimethylase 25 251 8.8E-49 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 PANTHER PTHR11727 20 283 2.1E-78 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MED134_RS08265 8230eb09a055ae2727cb99a4ea4f076f 288 Gene3D G3DSA:1.10.8.100 223 283 1.4E-19 T 22-04-2016 IPR023165 rRNA adenine dimethylase-like MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 Pfam PF11700 Vacuole effluxer Atg22 like 151 433 8.7E-56 T 22-04-2016 IPR024671 Autophagy-related protein 22-like MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 Pfam PF11700 Vacuole effluxer Atg22 like 9 147 4.3E-23 T 22-04-2016 IPR024671 Autophagy-related protein 22-like MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 Gene3D G3DSA:1.20.1250.20 254 433 8.3E-16 T 22-04-2016 MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 PANTHER PTHR23519 15 435 1.3E-51 T 22-04-2016 MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 Gene3D G3DSA:1.20.1250.20 67 205 7.2E-6 T 22-04-2016 MED134_RS04450 24f77217a5b7f3e7a9a9cc50a921db10 435 SUPERFAMILY SSF103473 10 435 1.03E-28 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS01450 fdcd3b3d3eda46b037399940e1f1ba6e 240 Gene3D G3DSA:3.20.20.140 21 216 1.1E-6 T 22-04-2016 MED134_RS01450 fdcd3b3d3eda46b037399940e1f1ba6e 240 PANTHER PTHR39181:SF1 20 213 4.2E-51 T 22-04-2016 MED134_RS01450 fdcd3b3d3eda46b037399940e1f1ba6e 240 SUPERFAMILY SSF89550 20 214 2.55E-17 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 MED134_RS01450 fdcd3b3d3eda46b037399940e1f1ba6e 240 PANTHER PTHR39181 20 213 4.2E-51 T 22-04-2016 MED134_RS01450 fdcd3b3d3eda46b037399940e1f1ba6e 240 PIRSF PIRSF016557 20 239 5.8E-47 T 22-04-2016 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 UniPathway: UPA00934 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 SMART SM00387 474 593 6.9E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 Gene3D G3DSA:1.10.287.130 358 420 7.9E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 591 2.4E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 Gene3D G3DSA:3.30.565.10 421 591 9.0E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 PANTHER PTHR24423:SF518 346 590 5.0E-57 T 22-04-2016 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 SMART SM00388 366 434 3.6E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 SUPERFAMILY SSF55874 426 591 7.47E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 SUPERFAMILY SSF47384 352 433 1.29E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 7.0E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 7.0E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 534 7.0E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 Pfam PF13689 Domain of unknown function (DUF4154) 36 167 7.0E-23 T 22-04-2016 IPR025293 Protein of unknown function DUF4154 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 367 432 1.7E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14725 59341f283f39161347ebd5ab52bcac2b 593 PANTHER PTHR24423 346 590 5.0E-57 T 22-04-2016 MED134_RS01210 e77fe38c83548bbd1dc4361a013376e4 194 PIRSF PIRSF011489 1 193 2.6E-55 T 22-04-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 MED134_RS01210 e77fe38c83548bbd1dc4361a013376e4 194 PANTHER PTHR38764:SF1 2 194 3.2E-44 T 22-04-2016 MED134_RS01210 e77fe38c83548bbd1dc4361a013376e4 194 Pfam PF04336 Protein of unknown function, DUF479 81 185 3.6E-33 T 22-04-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 MED134_RS01210 e77fe38c83548bbd1dc4361a013376e4 194 PANTHER PTHR38764 2 194 3.2E-44 T 22-04-2016 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 PANTHER PTHR11647:SF70 1 417 4.2E-95 T 22-04-2016 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 Gene3D G3DSA:2.30.40.10 1 74 4.2E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 SUPERFAMILY SSF51338 3 58 2.38E-13 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 SUPERFAMILY SSF51338 369 416 2.38E-13 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 Gene3D G3DSA:3.20.20.140 75 400 4.0E-66 T 22-04-2016 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 PANTHER PTHR11647 1 417 4.2E-95 T 22-04-2016 MED134_RS02030 929848c24e1738bcc5ffa7e2628fbe6d 417 SUPERFAMILY SSF51556 57 350 1.57E-74 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS02065 232e39435600fc2e141784384762cdd8 224 Gene3D G3DSA:1.10.1670.10 124 192 4.8E-21 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal MED134_RS02065 232e39435600fc2e141784384762cdd8 224 Hamap MF_00942 Endonuclease III [nth]. 1 210 30.461 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 PANTHER PTHR10359:SF18 7 191 1.2E-64 T 22-04-2016 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 169 7.3E-19 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 PANTHER PTHR10359 7 191 1.2E-64 T 22-04-2016 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 Gene3D G3DSA:1.10.340.30 25 123 3.8E-28 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 SMART SM00478 39 186 5.4E-44 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 PIRSF PIRSF001435 1 205 5.7E-37 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 MED134_RS02065 232e39435600fc2e141784384762cdd8 224 SUPERFAMILY SSF48150 2 191 4.87E-53 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 160 3.7E-28 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00101 Aspartate carbamoyltransferase signature 146 163 5.4E-5 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 279 5.4E-5 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 5.4E-5 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PANTHER PTHR11405:SF1 1 319 2.9E-59 T 22-04-2016 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 Gene3D G3DSA:3.40.50.1370 159 304 4.0E-41 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PANTHER PTHR11405 1 319 2.9E-59 T 22-04-2016 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 Gene3D G3DSA:3.40.50.1370 1 158 3.8E-46 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 SUPERFAMILY SSF53671 1 319 1.57E-60 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 188 312 3.9E-21 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 6.8E-12 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 279 6.8E-12 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11760 69ffa2b0384e624bab0018b8a951ed79 321 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 282 305 6.8E-12 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Gene3D G3DSA:3.30.300.20 283 345 8.0E-22 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Gene3D G3DSA:3.30.300.20 202 280 2.5E-33 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 SUPERFAMILY SSF54814 284 343 3.4E-11 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 408 25.886 T 22-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 344 4.1E-107 T 22-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 PANTHER PTHR22648:SF0 2 410 9.9E-97 T 22-04-2016 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Gene3D G3DSA:3.30.1480.10 3 125 1.4E-27 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Gene3D G3DSA:2.40.50.140 132 201 2.3E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 SUPERFAMILY SSF54814 203 280 2.22E-27 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Pfam PF08529 NusA N-terminal domain 6 124 2.6E-24 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 SUPERFAMILY SSF69705 3 127 9.42E-26 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 Pfam PF13184 NusA-like KH domain 233 301 3.6E-25 T 22-04-2016 IPR025249 KH domain, NusA-like GO:0003723 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 PANTHER PTHR22648 2 410 9.9E-97 T 22-04-2016 MED134_RS11175 7d2590bebf8d7e0d19be4e643c2ae568 410 SUPERFAMILY SSF50249 135 202 3.43E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 SUPERFAMILY SSF56436 175 388 4.98E-57 T 22-04-2016 IPR016187 C-type lectin fold MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 Pfam PF12867 DinB superfamily 13 141 2.8E-8 T 22-04-2016 IPR024775 DinB-like domain MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 PANTHER PTHR23150:SF24 2 389 3.8E-82 T 22-04-2016 MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 Gene3D G3DSA:3.90.1580.10 317 389 5.2E-16 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 Gene3D G3DSA:3.90.1580.10 169 312 1.1E-31 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 SUPERFAMILY SSF109854 5 139 7.32E-7 T 22-04-2016 MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 PANTHER PTHR23150 2 389 3.8E-82 T 22-04-2016 MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 Pfam PF03781 Sulfatase-modifying factor enzyme 1 317 389 1.2E-4 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 Pfam PF03781 Sulfatase-modifying factor enzyme 1 177 312 1.0E-18 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme MED134_RS07240 354a1c6b446ee481b706dad2b31ea6ab 389 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 8 388 1.1E-137 T 22-04-2016 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255|UniPathway: UPA01014 MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 Hamap MF_00984 Single-stranded DNA-binding protein. 5 112 28.974 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 Pfam PF00436 Single-strand binding protein family 6 108 3.3E-32 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 PANTHER PTHR10302 6 112 1.3E-33 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 SUPERFAMILY SSF50249 6 110 2.36E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 110 7.8E-36 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 Gene3D G3DSA:2.40.50.140 5 111 1.5E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS07865 1c571cf5c3bac33cf1279c965481d448 112 PIRSF PIRSF002070 5 112 7.7E-33 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS03685 d525011d6b2ea13dd5217ccc207dcc8c 127 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 22-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 MED134_RS03685 d525011d6b2ea13dd5217ccc207dcc8c 127 PANTHER PTHR10374 1 123 1.8E-12 T 22-04-2016 MED134_RS03685 d525011d6b2ea13dd5217ccc207dcc8c 127 Gene3D G3DSA:3.10.180.10 1 124 1.5E-24 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS03685 d525011d6b2ea13dd5217ccc207dcc8c 127 SUPERFAMILY SSF54593 6 123 2.69E-23 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS03685 d525011d6b2ea13dd5217ccc207dcc8c 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 7.7E-13 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 PANTHER PTHR11019 1 172 7.3E-70 T 22-04-2016 MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 PANTHER PTHR11019:SF115 1 172 7.3E-70 T 22-04-2016 MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 Gene3D G3DSA:3.40.50.880 1 174 2.4E-56 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 Pfam PF01965 DJ-1/PfpI family 3 171 1.3E-50 T 22-04-2016 IPR002818 DJ-1/PfpI MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 SUPERFAMILY SSF52317 1 172 6.36E-48 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02875 3a620d5cbf27165bb50fbb70e235b94b 182 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 172 3.5E-51 T 22-04-2016 IPR006286 Peptidase C56, PfpI GO:0016798 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 Gene3D G3DSA:3.30.70.1280 1 89 5.4E-32 T 22-04-2016 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 Pfam PF08002 Protein of unknown function (DUF1697) 1 135 6.7E-39 T 22-04-2016 IPR012545 Protein of unknown function DUF1697 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 PIRSF PIRSF008502 1 176 9.2E-44 T 22-04-2016 IPR012545 Protein of unknown function DUF1697 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 PANTHER PTHR36439 1 176 1.9E-34 T 22-04-2016 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 SUPERFAMILY SSF160379 1 174 6.54E-49 T 22-04-2016 MED134_RS10665 47adfbc70a50d54ef63b9e22e646a881 176 PANTHER PTHR36439:SF1 1 176 1.9E-34 T 22-04-2016 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 Gene3D G3DSA:3.30.70.100 174 258 1.7E-26 T 22-04-2016 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 Pfam PF00924 Mechanosensitive ion channel 63 260 1.4E-50 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 SUPERFAMILY SSF50182 106 171 1.05E-16 T 22-04-2016 IPR010920 LSM domain MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 PANTHER PTHR30221 1 263 7.2E-88 T 22-04-2016 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 SUPERFAMILY SSF82689 175 265 1.83E-26 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 Gene3D G3DSA:2.30.30.60 121 170 2.5E-17 T 22-04-2016 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 PANTHER PTHR30221:SF7 1 263 7.2E-88 T 22-04-2016 MED134_RS11410 06ff6b7f6ae5d026cbef83c49681304b 272 SUPERFAMILY SSF82861 18 104 1.05E-19 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS01890 44536ba338d71f4bb73be213ba4a8493 344 Pfam PF04231 Endonuclease I 35 245 1.7E-39 T 22-04-2016 IPR007346 Endonuclease I GO:0004518 MED134_RS01890 44536ba338d71f4bb73be213ba4a8493 344 PANTHER PTHR33607 18 343 1.6E-32 T 22-04-2016 MED134_RS01890 44536ba338d71f4bb73be213ba4a8493 344 PANTHER PTHR33607:SF2 18 343 1.6E-32 T 22-04-2016 MED134_RS01890 44536ba338d71f4bb73be213ba4a8493 344 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 276 344 9.3E-14 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS01890 44536ba338d71f4bb73be213ba4a8493 344 SUPERFAMILY SSF54060 47 245 2.94E-32 T 22-04-2016 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 Pfam PF13807 G-rich domain on putative tyrosine kinase 451 522 9.3E-10 T 22-04-2016 IPR032807 Tyrosine kinase, G-rich domain MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 Pfam PF13614 AAA domain 596 723 4.4E-12 T 22-04-2016 IPR025669 AAA domain MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 PANTHER PTHR32309:SF13 194 789 4.2E-149 T 22-04-2016 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 PANTHER PTHR32309:SF13 1 124 4.2E-149 T 22-04-2016 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 568 779 4.2E-39 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 PANTHER PTHR32309 194 789 4.2E-149 T 22-04-2016 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 PANTHER PTHR32309 1 124 4.2E-149 T 22-04-2016 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 SUPERFAMILY SSF52540 590 772 4.39E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 Pfam PF02706 Chain length determinant protein 12 259 3.2E-18 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 MED134_RS01445 bfadb5b0bcd281560e1d1dc4867cf860 800 Gene3D G3DSA:3.40.50.300 589 797 1.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06175 d11028186a4adfe219708ed3fb404ea5 209 Gene3D G3DSA:3.30.70.100 22 91 1.9E-11 T 22-04-2016 MED134_RS06175 d11028186a4adfe219708ed3fb404ea5 209 Gene3D G3DSA:3.30.70.100 122 184 4.1E-9 T 22-04-2016 MED134_RS06175 d11028186a4adfe219708ed3fb404ea5 209 Pfam PF00403 Heavy-metal-associated domain 30 91 4.9E-8 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS06175 d11028186a4adfe219708ed3fb404ea5 209 SUPERFAMILY SSF55008 130 190 4.97E-10 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS06175 d11028186a4adfe219708ed3fb404ea5 209 SUPERFAMILY SSF55008 23 93 2.49E-10 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF50677 293 481 1.15E-47 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:1.10.730.10 761 894 2.5E-39 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 288 466 9.0E-60 T 22-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 213 958 4.9E-211 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 728 958 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 216 274 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 355 521 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 307 332 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 558 659 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946:SF7 1 157 4.4E-302 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 731 758 4.3E-5 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 11 155 1.2E-16 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 612 634 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 282 301 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 137 154 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 645 655 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 572 590 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PRINTS PR00985 Leucyl-tRNA synthetase signature 253 266 2.8E-40 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 728 958 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 216 274 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 355 521 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 307 332 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 558 659 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 PANTHER PTHR11946 1 157 4.4E-302 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 959 20.818 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:3.40.50.620 731 760 6.9E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:3.40.50.620 491 661 6.9E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:3.40.50.620 1 156 6.9E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:3.40.50.620 215 290 6.9E-148 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Pfam PF08264 Anticodon-binding domain of tRNA 810 919 1.1E-14 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF47323 775 958 5.42E-31 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 Gene3D G3DSA:3.90.740.10 291 490 4.1E-58 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF52374 216 293 1.44E-104 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF52374 732 780 1.44E-104 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF52374 1 157 1.44E-104 T 22-04-2016 MED134_RS10145 d205039fa153016ed730787ef83d81a0 959 SUPERFAMILY SSF52374 482 699 1.44E-104 T 22-04-2016 MED134_RS05715 6d451c3353d702a4f1a14b1e7143689f 161 PIRSF PIRSF032285 1 161 1.3E-47 T 22-04-2016 IPR011235 MepB-like MED134_RS05715 6d451c3353d702a4f1a14b1e7143689f 161 PANTHER PTHR41289 7 155 5.7E-27 T 22-04-2016 MED134_RS05715 6d451c3353d702a4f1a14b1e7143689f 161 Pfam PF08877 MepB protein 27 146 1.9E-46 T 22-04-2016 IPR011235 MepB-like MED134_RS10300 572d5590dacaa2111bbc14cd3279f2f3 76 SUPERFAMILY SSF50037 9 73 4.12E-16 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal MED134_RS10300 572d5590dacaa2111bbc14cd3279f2f3 76 SMART SM00899 3 74 3.0E-12 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MED134_RS10300 572d5590dacaa2111bbc14cd3279f2f3 76 Pfam PF04023 FeoA domain 6 73 1.9E-13 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 1.0E-33 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 21.62 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 22-04-2016 IPR006162 Phosphopantetheine attachment site MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 Pfam PF00550 Phosphopantetheine attachment site 7 73 8.8E-16 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 75 1.0E-9 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 Gene3D G3DSA:1.10.1200.10 3 75 2.1E-31 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 PANTHER PTHR20863 3 75 2.4E-26 T 22-04-2016 MED134_RS08955 6d3c0f20496e2d665cfa7b5baa082557 77 SUPERFAMILY SSF47336 2 76 3.8E-22 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 PIRSF PIRSF006246 1 116 2.2E-45 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 Gene3D G3DSA:2.40.40.20 1 114 1.7E-49 T 22-04-2016 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 PANTHER PTHR21012 2 111 2.2E-56 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 116 63.167 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 93 9.0E-29 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 PANTHER PTHR21012:SF0 2 111 2.2E-56 T 22-04-2016 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 Pfam PF02261 Aspartate decarboxylase 1 113 2.7E-47 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 SUPERFAMILY SSF50692 1 114 4.1E-44 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain MED134_RS07995 9713e61ab1bdee5c7c07d6b5085501e1 116 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 114 1.0E-44 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 251 2.9E-84 T 22-04-2016 MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 PANTHER PTHR22748 1 254 3.5E-104 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 252 1.1E-88 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 244 8.1E-26 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 SUPERFAMILY SSF56219 1 253 1.7E-78 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 Gene3D G3DSA:3.60.10.10 1 252 5.8E-90 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 22-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MED134_RS08035 dbb3c6ec1c09f1eb9257319bfa16f09e 254 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 187 202 - T 22-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 Gene3D G3DSA:3.30.70.560 2 155 2.3E-45 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 PANTHER PTHR20941 2 155 7.8E-51 T 22-04-2016 MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 Gene3D G3DSA:3.40.50.300 162 356 1.1E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 SUPERFAMILY SSF55083 2 155 4.32E-44 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 Pfam PF01712 Deoxynucleoside kinase 179 369 8.2E-42 T 22-04-2016 IPR031314 Deoxynucleoside kinase domain MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 SUPERFAMILY SSF52540 178 370 7.47E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 132 5.2E-35 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS07410 67b50c7cb54eabd53e4c0fa66c869d2f 372 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 2.9E-32 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 SUPERFAMILY SSF52833 1 150 6.16E-47 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 PANTHER PTHR10681:SF122 3 150 5.1E-48 T 22-04-2016 MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 Pfam PF00578 AhpC/TSA family 5 128 2.5E-38 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 PANTHER PTHR10681 3 150 5.1E-48 T 22-04-2016 MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 Gene3D G3DSA:3.40.30.10 2 150 1.3E-45 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS00035 cb9f50c8ee75f5bfaedcbd8b5fa2b7d1 150 PIRSF PIRSF000239 1 150 3.4E-25 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 MED134_RS12055 627e6b304f31bfe5893c1381e6e4da3b 93 PANTHER PTHR31435 1 93 7.1E-17 T 22-04-2016 MED134_RS12055 627e6b304f31bfe5893c1381e6e4da3b 93 SUPERFAMILY SSF55729 3 92 2.01E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS12055 627e6b304f31bfe5893c1381e6e4da3b 93 Pfam PF14542 GCN5-related N-acetyl-transferase 14 91 1.8E-20 T 22-04-2016 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MED134_RS12055 627e6b304f31bfe5893c1381e6e4da3b 93 Gene3D G3DSA:3.40.630.30 1 93 1.3E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 SUPERFAMILY SSF52540 25 344 1.0E-87 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 PANTHER PTHR23408:SF17 22 348 3.9E-153 T 22-04-2016 MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 38 343 6.8E-98 T 22-04-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 PANTHER PTHR23408 22 348 3.9E-153 T 22-04-2016 MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 SMART SM00382 74 225 5.7E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 Gene3D G3DSA:3.40.50.300 78 278 6.4E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 Gene3D G3DSA:1.20.5.170 18 77 6.0E-18 T 22-04-2016 MED134_RS13270 e3516b552cfa00d022daa18b198dd61c 348 Pfam PF03308 ArgK protein 43 314 9.4E-96 T 22-04-2016 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Pfam PF01979 Amidohydrolase family 838 931 3.8E-11 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Gene3D G3DSA:2.30.40.10 557 666 1.5E-25 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 PANTHER PTHR11271:SF39 532 959 5.5E-35 T 22-04-2016 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Gene3D G3DSA:2.30.40.10 837 933 2.1E-21 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 PANTHER PTHR11271 532 959 5.5E-35 T 22-04-2016 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Gene3D G3DSA:2.30.40.10 34 92 1.6E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Gene3D G3DSA:2.30.40.10 404 437 1.6E-15 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 SUPERFAMILY SSF51338 548 617 6.34E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 SUPERFAMILY SSF51338 898 934 6.34E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 SUPERFAMILY SSF51338 37 91 8.1E-11 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 SUPERFAMILY SSF51338 391 425 8.1E-11 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 SUPERFAMILY SSF51556 617 899 2.12E-22 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS03040 d4f72bcc0e9e1466c78f42b9b5ddb4f2 986 Gene3D G3DSA:2.30.40.10 331 403 3.6E-16 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 PANTHER PTHR10314 15 395 1.7E-208 T 22-04-2016 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 Gene3D G3DSA:3.40.50.1100 106 180 1.2E-19 T 22-04-2016 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 SUPERFAMILY SSF53686 12 397 5.63E-137 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 Gene3D G3DSA:3.40.50.1100 181 398 1.0E-82 T 22-04-2016 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 PANTHER PTHR10314:SF3 15 395 1.7E-208 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 384 3.8E-50 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 88 102 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 PIRSF PIRSF001413 3 399 9.4E-163 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 10 397 50.131 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS13020 340a6bb25e6284529db56c4cb87390c8 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 396 6.1E-178 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 SUPERFAMILY SSF48179 184 286 3.32E-33 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 182 207 - T 22-04-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 182 1.1E-65 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 Gene3D G3DSA:3.40.50.720 1 186 8.6E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05135 03afecb2f421077638a91249d172da5b 295 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 281 5.2E-34 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 PANTHER PTHR23309 1 283 2.2E-146 T 22-04-2016 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 SUPERFAMILY SSF51735 1 184 1.72E-62 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05135 03afecb2f421077638a91249d172da5b 295 PIRSF PIRSF000105 1 293 1.3E-94 T 22-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MED134_RS05135 03afecb2f421077638a91249d172da5b 295 Gene3D G3DSA:1.10.1040.10 187 282 7.8E-35 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 Gene3D G3DSA:3.40.30.10 2 151 1.5E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 Pfam PF00578 AhpC/TSA family 6 133 3.7E-39 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 PIRSF PIRSF000239 1 143 6.8E-21 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 PANTHER PTHR10681 4 151 1.2E-45 T 22-04-2016 MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 SUPERFAMILY SSF52833 4 151 2.54E-47 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02060 63ab18a133dc410530129abb5ee50502 151 PANTHER PTHR10681:SF113 4 151 1.2E-45 T 22-04-2016 MED134_RS10870 9e055f7b67976b64ef18856c116e0dfd 437 SUPERFAMILY SSF101960 17 429 3.14E-105 T 22-04-2016 MED134_RS10870 9e055f7b67976b64ef18856c116e0dfd 437 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 404 1.2E-75 T 22-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MED134_RS10870 9e055f7b67976b64ef18856c116e0dfd 437 PANTHER PTHR30508:SF0 27 436 7.3E-114 T 22-04-2016 MED134_RS10870 9e055f7b67976b64ef18856c116e0dfd 437 PANTHER PTHR30508 27 436 7.3E-114 T 22-04-2016 MED134_RS10870 9e055f7b67976b64ef18856c116e0dfd 437 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 145 420 1.9E-84 T 22-04-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 Pfam PF08281 Sigma-70, region 4 106 154 3.3E-7 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 Gene3D G3DSA:1.10.1740.10 6 98 4.7E-19 T 22-04-2016 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 Pfam PF04542 Sigma-70 region 2 11 74 2.9E-11 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 PANTHER PTHR30173:SF8 7 161 8.4E-34 T 22-04-2016 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 1.8E-21 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 PANTHER PTHR30173 7 161 8.4E-34 T 22-04-2016 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 SUPERFAMILY SSF88659 85 161 5.76E-7 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 Gene3D G3DSA:1.10.10.10 102 162 4.4E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08545 f906a926dfbf4606fcdca9d4b4a74e56 166 SUPERFAMILY SSF88946 7 87 1.41E-17 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 38 1078 27.414 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF52540 321 410 5.87E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SMART SM00982 970 1076 8.6E-24 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 238 1043 4.2E-275 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Gene3D G3DSA:3.30.2060.10 143 218 7.3E-15 T 22-04-2016 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SMART SM01058 431 528 3.9E-32 T 22-04-2016 IPR003711 CarD-like/TRCF domain MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Pfam PF03461 TRCF domain 972 1063 3.8E-24 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Pfam PF02559 CarD-like/TRCF domain 432 527 5.8E-22 T 22-04-2016 IPR003711 CarD-like/TRCF domain MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Gene3D G3DSA:3.40.50.300 540 738 6.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 PANTHER PTHR14025:SF21 350 1043 0.0 T 22-04-2016 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Pfam PF00270 DEAD/DEAH box helicase 577 716 1.6E-16 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF52540 490 736 3.53E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SMART SM00490 778 862 7.1E-17 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF52540 22 308 1.14E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 PANTHER PTHR14025 350 1043 0.0 T 22-04-2016 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF143517 958 1092 5.49E-32 T 22-04-2016 MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF52540 734 942 3.25E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Pfam PF00271 Helicase conserved C-terminal domain 760 861 2.4E-15 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SUPERFAMILY SSF141259 423 500 3.53E-18 T 22-04-2016 IPR003711 CarD-like/TRCF domain MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 Gene3D G3DSA:3.40.50.300 751 908 1.2E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08540 93cc4f1fde531ff948e97adf65f1a3fc 1132 SMART SM00487 552 742 2.3E-31 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 Pfam PF00892 EamA-like transporter family 145 283 4.1E-11 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 Pfam PF00892 EamA-like transporter family 9 136 1.2E-8 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 PANTHER PTHR22911:SF71 4 294 1.4E-61 T 22-04-2016 MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 SUPERFAMILY SSF103481 39 137 3.92E-6 T 22-04-2016 MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 PANTHER PTHR22911 4 294 1.4E-61 T 22-04-2016 MED134_RS05765 47e6b71c4e95eb692db3e06f11e75846 301 SUPERFAMILY SSF103481 200 284 1.57E-5 T 22-04-2016 MED134_RS03370 c6bfe2d71bd8a711624cbe89f6014925 675 Pfam PF03571 Peptidase family M49 236 460 1.9E-34 T 22-04-2016 MED134_RS03370 c6bfe2d71bd8a711624cbe89f6014925 675 PANTHER PTHR23422 16 638 5.1E-184 T 22-04-2016 MED134_RS03370 c6bfe2d71bd8a711624cbe89f6014925 675 PANTHER PTHR23422:SF12 16 638 5.1E-184 T 22-04-2016 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 Pfam PF04055 Radical SAM superfamily 51 204 8.0E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 PIRSF PIRSF001619 1 321 3.3E-129 T 22-04-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 PANTHER PTHR22976 1 348 6.1E-169 T 22-04-2016 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 TIGRFAM TIGR00433 bioB: biotin synthase 15 312 5.1E-116 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 Hamap MF_01694 Biotin synthase [bioB]. 6 315 39.729 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 PANTHER PTHR22976:SF19 1 348 6.1E-169 T 22-04-2016 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 SMART SM00876 222 314 2.5E-42 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 SMART SM00729 44 251 9.6E-36 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 Gene3D G3DSA:3.20.20.70 6 315 3.5E-97 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 222 312 5.0E-21 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 MED134_RS07915 f3b86a0ec451463d495c267c5fcc110c 364 SUPERFAMILY SSF102114 6 314 8.76E-86 T 22-04-2016 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 SUPERFAMILY SSF46906 67 139 7.33E-27 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 Gene3D G3DSA:3.30.1550.10 2 71 1.0E-35 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 30.788 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 SUPERFAMILY SSF54747 3 72 1.83E-28 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 9.3E-25 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 PANTHER PTHR11661 1 141 2.6E-64 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 SMART SM00649 9 140 3.1E-76 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-14 T 22-04-2016 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 Gene3D G3DSA:1.10.10.250 72 140 2.9E-32 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 22-04-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 6.5E-63 T 22-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 MED134_RS04905 3bf7b90a2988ccdf967284687efae6d7 146 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 1.0E-27 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 SUPERFAMILY SSF52374 29 347 6.7E-89 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:3.90.800.10 100 208 1.6E-43 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 29 556 4.0E-225 T 22-04-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:3.40.50.620 28 96 7.5E-34 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:3.40.50.620 211 263 7.5E-34 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:2.40.240.10 466 552 2.0E-33 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 338 1.2E-93 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 554 48.793 T 22-04-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 PANTHER PTHR11451 268 588 1.1E-215 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 PANTHER PTHR11451 9 246 1.1E-215 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 PANTHER PTHR11451:SF29 268 588 1.1E-215 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 PANTHER PTHR11451:SF29 9 246 1.1E-215 T 22-04-2016 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 534 3.6E-62 T 22-04-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: REACT_71 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:1.10.1160.10 264 340 1.1E-36 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 SUPERFAMILY SSF50715 341 553 1.67E-74 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 MED134_RS09125 2a1cef389e71eaed529e22a5608a0a22 677 Gene3D G3DSA:2.40.240.10 349 465 5.1E-47 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 MED134_RS02680 cb24853cc9ace598c2f1863c8b2e6226 110 SUPERFAMILY SSF55159 37 108 5.62E-17 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 MED134_RS02680 cb24853cc9ace598c2f1863c8b2e6226 110 Pfam PF01253 Translation initiation factor SUI1 42 104 2.1E-13 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 MED134_RS02680 cb24853cc9ace598c2f1863c8b2e6226 110 Gene3D G3DSA:3.30.780.10 37 110 1.7E-25 T 22-04-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 131 7.0E-36 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 134 2.0E-35 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 4 135 21.967 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 SUPERFAMILY SSF81330 14 127 1.26E-29 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 14 27 - T 22-04-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 7 21 3.2E-10 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 85 93 3.2E-10 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 94 103 3.2E-10 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 PANTHER PTHR30266 3 135 1.1E-34 T 22-04-2016 MED134_RS04445 76294fee0111f7f2b5fd735fa701a44e 144 PANTHER PTHR30266:SF2 3 135 1.1E-34 T 22-04-2016 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Gene3D G3DSA:1.10.8.60 186 258 1.4E-30 T 22-04-2016 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 SMART SM00382 54 188 1.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 SUPERFAMILY SSF52540 23 254 6.11E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 13 238 5.8E-111 T 22-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 PANTHER PTHR13779:SF25 13 330 3.3E-169 T 22-04-2016 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 1.8E-34 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 PANTHER PTHR13779 13 330 3.3E-169 T 22-04-2016 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 330 8.0E-30 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 340 162.706 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 SUPERFAMILY SSF46785 260 329 9.98E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 8.3E-138 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Gene3D G3DSA:3.40.50.300 23 177 6.2E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11230 ef11a5ad566cd0aaa0579995203e0358 340 Gene3D G3DSA:1.10.10.10 260 329 5.9E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04375 c10650e61bdd2b50520051c799dd27dc 93 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 91 19.999 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MED134_RS04375 c10650e61bdd2b50520051c799dd27dc 93 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 2 90 4.6E-29 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MED134_RS04375 c10650e61bdd2b50520051c799dd27dc 93 Gene3D G3DSA:3.30.1360.20 2 91 1.3E-32 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MED134_RS04375 c10650e61bdd2b50520051c799dd27dc 93 PANTHER PTHR12599 3 91 4.7E-28 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MED134_RS04375 c10650e61bdd2b50520051c799dd27dc 93 SUPERFAMILY SSF55248 2 91 4.32E-32 T 22-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 185 7.1E-56 T 22-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 PANTHER PTHR12213 1 186 3.1E-77 T 22-04-2016 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 Gene3D G3DSA:1.20.1200.10 12 188 2.6E-62 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 185 6.0E-35 T 22-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 Pfam PF01923 Cobalamin adenosyltransferase 3 173 4.8E-60 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MED134_RS13315 1bcdcf5b61dd8dda2fb485d9b71dfbd5 191 SUPERFAMILY SSF89028 1 186 1.82E-60 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MED134_RS10705 a5907d23c1f8a6016b4d475e326e0466 257 SUPERFAMILY SSF48613 13 246 4.82E-12 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 MED134_RS10705 a5907d23c1f8a6016b4d475e326e0466 257 Gene3D G3DSA:1.20.910.10 7 253 8.1E-14 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 MED134_RS10705 a5907d23c1f8a6016b4d475e326e0466 257 Pfam PF11251 Protein of unknown function (DUF3050) 16 246 1.4E-99 T 22-04-2016 IPR024423 Protein of unknown function DUF3050 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 PANTHER PTHR24960 64 114 2.9E-19 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 PANTHER PTHR24960 1 44 2.9E-19 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 SUPERFAMILY SSF54862 64 100 1.19E-14 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 SUPERFAMILY SSF54862 4 29 1.19E-14 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 PANTHER PTHR24960:SF38 64 114 2.9E-19 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 PANTHER PTHR24960:SF38 1 44 2.9E-19 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 Pfam PF12838 4Fe-4S dicluster domain 9 91 1.2E-7 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 Gene3D G3DSA:3.30.70.20 3 28 8.3E-15 T 22-04-2016 MED134_RS02970 4eb01945c33e5532c7943dc7c16e1356 117 Gene3D G3DSA:3.30.70.20 63 106 8.3E-15 T 22-04-2016 MED134_RS11670 b6bce17dfb1b535fca769c170a7dc501 212 Gene3D G3DSA:3.30.420.10 13 159 4.2E-42 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS11670 b6bce17dfb1b535fca769c170a7dc501 212 Pfam PF01351 Ribonuclease HII 13 196 9.5E-39 T 22-04-2016 IPR024567 Ribonuclease HII/HIII domain MED134_RS11670 b6bce17dfb1b535fca769c170a7dc501 212 PANTHER PTHR10954 14 196 1.4E-60 T 22-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 MED134_RS11670 b6bce17dfb1b535fca769c170a7dc501 212 SUPERFAMILY SSF53098 4 202 6.22E-63 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS11670 b6bce17dfb1b535fca769c170a7dc501 212 Hamap MF_00052_B Ribonuclease HII [rnhB]. 11 198 32.339 T 22-04-2016 IPR022898 Ribonuclease HII GO:0004523 MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 PANTHER PTHR33594 1 216 1.4E-80 T 22-04-2016 MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 SMART SM00471 23 139 8.0E-7 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 PANTHER PTHR33594:SF1 1 216 1.4E-80 T 22-04-2016 MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 SUPERFAMILY SSF109604 4 216 2.51E-75 T 22-04-2016 MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 Gene3D G3DSA:1.10.3210.10 186 216 5.8E-49 T 22-04-2016 IPR006674 HD domain MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 Gene3D G3DSA:1.10.3210.10 3 143 5.8E-49 T 22-04-2016 IPR006674 HD domain MED134_RS08595 46300cd42239797cfcab79f413743aa4 218 Pfam PF01966 HD domain 30 129 6.2E-8 T 22-04-2016 IPR006674 HD domain MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 SUPERFAMILY SSF55486 5 673 4.0E-195 T 22-04-2016 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 PANTHER PTHR11804:SF8 4 676 1.2E-261 T 22-04-2016 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 Gene3D G3DSA:3.40.390.10 358 501 3.6E-56 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 PANTHER PTHR11804 4 676 1.2E-261 T 22-04-2016 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 Pfam PF01432 Peptidase family M3 225 673 2.2E-145 T 22-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 Gene3D G3DSA:1.10.1370.10 143 348 1.0E-131 T 22-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 Gene3D G3DSA:1.10.1370.10 502 674 1.0E-131 T 22-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MED134_RS12005 2dcdabe798cec2fadd1f0e36ff45b884 676 Gene3D G3DSA:1.20.1050.40 14 142 1.0E-26 T 22-04-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 PANTHER PTHR21535 51 351 3.7E-62 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 Pfam PF01544 CorA-like Mg2+ transporter protein 58 347 3.1E-70 T 22-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 Gene3D G3DSA:1.20.58.340 275 351 6.4E-31 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 31 351 2.7E-91 T 22-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 Gene3D G3DSA:1.20.58.340 161 272 8.6E-39 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 PANTHER PTHR21535:SF33 51 351 3.7E-62 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 Gene3D G3DSA:3.30.460.20 8 160 4.5E-40 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 SUPERFAMILY SSF143865 10 284 2.48E-72 T 22-04-2016 MED134_RS00225 900e49ff53e5a82a30275148d0e82320 351 SUPERFAMILY SSF144083 286 349 6.8E-22 T 22-04-2016 MED134_RS07710 c11ebd9aaf6ac6a43c25f39d05f0df96 350 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 77 294 8.0E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS07710 c11ebd9aaf6ac6a43c25f39d05f0df96 350 SUPERFAMILY SSF56219 30 345 1.19E-27 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS07710 c11ebd9aaf6ac6a43c25f39d05f0df96 350 Gene3D G3DSA:3.60.10.10 31 345 3.5E-9 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 SUPERFAMILY SSF69318 965 1013 3.14E-5 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Pfam PF07593 ASPIC and UnbV 521 587 6.5E-19 T 22-04-2016 IPR011519 ASPIC/UnbV MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026:SF0 357 419 6.5E-31 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026:SF0 57 328 6.5E-31 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026:SF0 437 585 6.5E-31 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 SUPERFAMILY SSF69318 53 402 5.23E-75 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 SUPERFAMILY SSF69318 437 500 5.23E-75 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 SUPERFAMILY SSF69318 888 912 3.14E-5 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Gene3D G3DSA:2.130.10.130 151 401 4.1E-31 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Gene3D G3DSA:2.130.10.130 746 875 7.1E-7 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Gene3D G3DSA:2.130.10.130 61 150 1.2E-9 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Gene3D G3DSA:2.130.10.130 442 499 4.1E-31 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026 357 419 6.5E-31 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026 57 328 6.5E-31 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 PANTHER PTHR16026 437 585 6.5E-31 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 SUPERFAMILY SSF69318 612 876 6.67E-25 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 439 487 4.0E-7 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 70 133 2.1E-12 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 250 312 3.8E-9 T 22-04-2016 MED134_RS10635 dffef3f3298de2ed467ea828ff7c4aae 1081 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 139 189 5.5E-8 T 22-04-2016 MED134_RS10685 10ed526b6fbae43c33483604f4fec181 301 Pfam PF01040 UbiA prenyltransferase family 51 266 3.6E-25 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 MED134_RS10685 10ed526b6fbae43c33483604f4fec181 301 PANTHER PTHR11048 54 300 1.5E-15 T 22-04-2016 MED134_RS10685 10ed526b6fbae43c33483604f4fec181 301 PANTHER PTHR11048:SF27 54 300 1.5E-15 T 22-04-2016 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 SUPERFAMILY SSF51621 34 854 8.0E-215 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PANTHER PTHR30523:SF0 88 859 1.2E-163 T 22-04-2016 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PANTHER PTHR30523 88 859 1.2E-163 T 22-04-2016 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 551 580 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 509 529 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 142 155 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 183 199 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 686 712 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 238 253 1.4E-28 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 Pfam PF00311 Phosphoenolpyruvate carboxylase 304 847 7.0E-112 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS01285 ac0a97f48fc3c5af9ee481c011812912 859 Pfam PF00311 Phosphoenolpyruvate carboxylase 139 285 5.9E-20 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MED134_RS14130 eb2db17ae6c79d2e07b845036839f69d 276 Pfam PF12679 ABC-2 family transporter protein 66 276 1.7E-8 T 22-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 MED134_RS02395 50c18c86e4d839daa698647cd5b6d57d 162 PANTHER PTHR11803 45 162 2.2E-38 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS02395 50c18c86e4d839daa698647cd5b6d57d 162 Pfam PF01042 Endoribonuclease L-PSP 48 159 1.5E-31 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS02395 50c18c86e4d839daa698647cd5b6d57d 162 Gene3D G3DSA:3.30.1330.40 46 161 1.1E-37 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS02395 50c18c86e4d839daa698647cd5b6d57d 162 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 41 159 1.4E-34 T 22-04-2016 IPR006056 RidA family MED134_RS02395 50c18c86e4d839daa698647cd5b6d57d 162 SUPERFAMILY SSF55298 39 161 4.71E-36 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS02415 90a59a6a4b291fceb1600673d425fc5d 281 Pfam PF12146 Serine aminopeptidase, S33 77 190 3.2E-11 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS02415 90a59a6a4b291fceb1600673d425fc5d 281 PANTHER PTHR10992 69 279 7.5E-23 T 22-04-2016 MED134_RS02415 90a59a6a4b291fceb1600673d425fc5d 281 Gene3D G3DSA:3.40.50.1820 69 277 1.9E-29 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS02415 90a59a6a4b291fceb1600673d425fc5d 281 SUPERFAMILY SSF53474 69 278 2.27E-33 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00505 b2819709ba87386e9c3b35ce029b0eb0 1500 PANTHER PTHR32387 42 337 3.0E-12 T 22-04-2016 MED134_RS00505 b2819709ba87386e9c3b35ce029b0eb0 1500 SUPERFAMILY SSF55874 40 126 3.46E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00505 b2819709ba87386e9c3b35ce029b0eb0 1500 Pfam PF13020 Domain of unknown function (DUF3883) 1393 1471 2.1E-11 T 22-04-2016 IPR024975 Domain of unknown function DUF3883 MED134_RS00505 b2819709ba87386e9c3b35ce029b0eb0 1500 Gene3D G3DSA:3.30.565.10 42 139 1.5E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 Gene3D G3DSA:3.40.50.2000 1 209 4.0E-85 T 22-04-2016 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 PANTHER PTHR18964 1 371 9.9E-183 T 22-04-2016 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 PANTHER PTHR18964:SF2 1 371 9.9E-183 T 22-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 369 5.5E-151 T 22-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 Gene3D G3DSA:3.40.50.2000 210 370 2.6E-66 T 22-04-2016 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 SUPERFAMILY SSF53756 1 370 1.81E-130 T 22-04-2016 MED134_RS01375 45a2377b52bcfcdd2530521ed0d2678c 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 369 9.3E-121 T 22-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 183 200 - T 22-04-2016 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 PANTHER PTHR10088 6 265 1.6E-106 T 22-04-2016 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 Pfam PF01380 SIS domain 125 206 3.7E-11 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 SUPERFAMILY SSF53697 7 245 1.31E-67 T 22-04-2016 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 6 261 3.2E-99 T 22-04-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 Gene3D G3DSA:3.40.50.10490 6 243 1.4E-76 T 22-04-2016 MED134_RS11715 5cb84f0cb98720b371b45abf49c1f564 271 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 265 33.325 T 22-04-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 PANTHER PTHR14552 1 107 1.2E-31 T 22-04-2016 MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 Gene3D G3DSA:1.10.287.1080 1 91 1.9E-25 T 22-04-2016 MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 SUPERFAMILY SSF101386 1 100 2.62E-26 T 22-04-2016 MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 PANTHER PTHR14552:SF13 1 107 1.2E-31 T 22-04-2016 MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 PIRSF PIRSF029904 1 108 1.8E-44 T 22-04-2016 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD MED134_RS05565 93a9cedb2e3b7c6e5404f8373bfba20b 108 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 100 1.4E-14 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 Gene3D G3DSA:1.10.10.410 93 149 5.2E-25 T 22-04-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 Pfam PF09424 Yqey-like protein 7 148 2.0E-46 T 22-04-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 SUPERFAMILY SSF89095 1 149 9.42E-39 T 22-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 PANTHER PTHR28055 1 149 1.4E-44 T 22-04-2016 MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 Gene3D G3DSA:1.10.1510.10 1 92 3.8E-26 T 22-04-2016 MED134_RS12555 fa73a571f589ae14efc0de1bdc4305a6 149 PANTHER PTHR28055:SF1 1 149 1.4E-44 T 22-04-2016 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 76 8.9E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 168 192 8.9E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 228 247 8.9E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 Pfam PF01061 ABC-2 type transporter 37 250 3.8E-24 T 22-04-2016 IPR013525 ABC-2 type transporter GO:0016020 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PANTHER PTHR30413:SF8 15 290 3.1E-51 T 22-04-2016 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PIRSF PIRSF006648 16 286 4.0E-15 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MED134_RS13350 d6fe56b93df2dc48e6317098047c1a6b 290 PANTHER PTHR30413 15 290 3.1E-51 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MED134_RS13660 f61dc9abab276b5df74f15f0dea1ca8d 592 SUPERFAMILY SSF56935 105 590 2.96E-22 T 22-04-2016 MED134_RS13660 f61dc9abab276b5df74f15f0dea1ca8d 592 Gene3D G3DSA:2.40.170.20 151 248 6.8E-16 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13660 f61dc9abab276b5df74f15f0dea1ca8d 592 Gene3D G3DSA:2.40.170.20 324 590 6.8E-16 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06385 906d69a9147e27f20580ccf4b436d72a 130 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 128 8.7E-22 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MED134_RS06385 906d69a9147e27f20580ccf4b436d72a 130 PANTHER PTHR30558 1 130 9.3E-17 T 22-04-2016 MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 Pfam PF08338 Domain of unknown function (DUF1731) 258 304 7.4E-18 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 Gene3D G3DSA:3.40.50.720 1 259 9.4E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 223 5.6E-15 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 PANTHER PTHR11092 1 305 2.5E-90 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 301 3.6E-84 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 MED134_RS13190 7b6a7e54e59b7df0e42ac2268da60afc 306 SUPERFAMILY SSF51735 1 305 5.0E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09310 ce44cf2c85073ce6f26b32ffc8ebec1a 426 SUPERFAMILY SSF56801 85 332 3.79E-13 T 22-04-2016 MED134_RS09310 ce44cf2c85073ce6f26b32ffc8ebec1a 426 PANTHER PTHR36932 12 360 1.6E-29 T 22-04-2016 MED134_RS09310 ce44cf2c85073ce6f26b32ffc8ebec1a 426 Gene3D G3DSA:3.40.50.980 165 258 6.3E-4 T 22-04-2016 MED134_RS09310 ce44cf2c85073ce6f26b32ffc8ebec1a 426 PANTHER PTHR36932:SF2 12 360 1.6E-29 T 22-04-2016 MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 PANTHER PTHR21366:SF0 3 134 9.3E-31 T 22-04-2016 MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 3.1E-21 T 22-04-2016 MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 3 130 1.1E-43 T 22-04-2016 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 Gene3D G3DSA:3.10.180.10 3 130 3.7E-41 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 PANTHER PTHR21366 3 134 9.3E-31 T 22-04-2016 MED134_RS06720 00923c3d137aa667767b2513f24cc6b9 134 SUPERFAMILY SSF54593 2 133 5.35E-32 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 Pfam PF01209 ubiE/COQ5 methyltransferase family 13 242 7.0E-69 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 PANTHER PTHR10108 11 242 1.4E-64 T 22-04-2016 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 10 242 34.456 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 150 164 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 PANTHER PTHR10108:SF24 11 242 1.4E-64 T 22-04-2016 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 Gene3D G3DSA:3.40.50.150 17 238 3.4E-47 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 19 242 3.4E-77 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 30 45 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 MED134_RS05490 340660dce087d00cb66a1bbcc84369c8 242 SUPERFAMILY SSF53335 4 236 1.46E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 SUPERFAMILY SSF49373 240 284 4.71E-6 T 22-04-2016 IPR008964 Invasin/intimin cell-adhesion fragments MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 Pfam PF02018 Carbohydrate binding domain 484 602 3.3E-7 T 22-04-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 Gene3D G3DSA:2.60.120.260 479 617 3.8E-24 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 Gene3D G3DSA:2.60.120.360 36 194 1.5E-10 T 22-04-2016 MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 SUPERFAMILY SSF49785 35 211 6.09E-30 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 SUPERFAMILY SSF49785 485 617 3.57E-26 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS14815 624e8e7829c7d9ceef17fd43410e2e23 619 Gene3D G3DSA:2.60.40.1080 239 286 1.6E-5 T 22-04-2016 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 Pfam PF05971 Protein of unknown function (DUF890) 1 281 5.0E-89 T 22-04-2016 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 1 282 43.992 T 22-04-2016 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 PANTHER PTHR13393 1 280 2.7E-91 T 22-04-2016 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 PANTHER PTHR13393:SF0 1 280 2.7E-91 T 22-04-2016 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 PIRSF PIRSF029038 1 282 4.5E-100 T 22-04-2016 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 Gene3D G3DSA:3.40.50.150 89 268 3.0E-10 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01810 423b0ec48f1f768c82ffb393b6cf8433 282 SUPERFAMILY SSF53335 37 280 1.14E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03940 60b1d3443128d10557a57c4942465041 256 PANTHER PTHR11142 1 253 2.0E-73 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 Gene3D G3DSA:3.30.70.660 109 243 3.5E-37 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 245 30.652 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 SUPERFAMILY SSF55120 2 251 1.31E-71 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 2.8E-52 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 PANTHER PTHR11142:SF0 1 253 2.0E-73 T 22-04-2016 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 Gene3D G3DSA:3.30.70.580 2 108 1.5E-33 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 PIRSF PIRSF001430 1 256 3.9E-73 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS03940 60b1d3443128d10557a57c4942465041 256 Pfam PF01416 tRNA pseudouridine synthase 144 246 1.7E-21 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 Gene3D G3DSA:2.130.10.10 1571 1726 3.6E-10 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 Pfam PF02128 Fungalysin metallopeptidase (M36) 245 604 1.0E-142 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 Gene3D G3DSA:2.60.40.60 1761 1798 6.5E-4 T 22-04-2016 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 PANTHER PTHR33478 46 609 4.1E-141 T 22-04-2016 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 48 91 3.7E-11 T 22-04-2016 IPR011096 FTP domain MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 SUPERFAMILY SSF55486 269 601 1.74E-62 T 22-04-2016 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 2091 2164 8.8E-15 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 SUPERFAMILY SSF63825 1124 1301 3.4E-8 T 22-04-2016 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 47 65 6.9E-10 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 407 427 6.9E-10 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 PRINTS PR00999 Fungalysin metallopeptidase (M36) signature 570 592 6.9E-10 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS10020 eb39a264c9b04c38b1371c442f931a40 2165 SUPERFAMILY SSF63825 1510 1721 3.14E-12 T 22-04-2016 MED134_RS08255 e9a4a10d6fffe9d4f31ae516c5e2b64d 141 PANTHER PTHR31793:SF6 6 141 2.3E-16 T 22-04-2016 MED134_RS08255 e9a4a10d6fffe9d4f31ae516c5e2b64d 141 SUPERFAMILY SSF54637 4 141 5.61E-29 T 22-04-2016 IPR029069 HotDog domain MED134_RS08255 e9a4a10d6fffe9d4f31ae516c5e2b64d 141 Gene3D G3DSA:3.10.129.10 3 141 3.7E-26 T 22-04-2016 IPR029069 HotDog domain MED134_RS08255 e9a4a10d6fffe9d4f31ae516c5e2b64d 141 Pfam PF13279 Thioesterase-like superfamily 14 138 8.7E-8 T 22-04-2016 MED134_RS08255 e9a4a10d6fffe9d4f31ae516c5e2b64d 141 PANTHER PTHR31793 6 141 2.3E-16 T 22-04-2016 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF00691 OmpA family 366 461 5.7E-24 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF02412 Thrombospondin type 3 repeat 293 310 7.4E-4 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF02412 Thrombospondin type 3 repeat 320 339 0.029 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF02412 Thrombospondin type 3 repeat 211 229 0.0016 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF02412 Thrombospondin type 3 repeat 266 285 0.0019 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Pfam PF02412 Thrombospondin type 3 repeat 239 256 0.0016 T 22-04-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: REACT_16888 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 SUPERFAMILY SSF103088 345 467 4.32E-39 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 SUPERFAMILY SSF103647 211 285 6.02E-13 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 PANTHER PTHR30128 365 470 1.1E-44 T 22-04-2016 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Gene3D G3DSA:4.10.1080.10 189 275 1.5E-14 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Gene3D G3DSA:4.10.1080.10 276 341 6.8E-12 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 Gene3D G3DSA:3.30.1330.60 362 469 8.0E-42 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 SUPERFAMILY SSF103647 264 340 9.02E-10 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 PRINTS PR01021 OMPA domain signature 367 389 2.6E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 PRINTS PR01021 OMPA domain signature 397 412 2.6E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS08995 9d2ba7d7c374e3aa4039558190f14abb 470 PRINTS PR01021 OMPA domain signature 412 428 2.6E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS09725 b24e88feb68fdbe80c685971febe72f3 169 Pfam PF13474 SnoaL-like domain 29 143 1.2E-30 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain MED134_RS09725 b24e88feb68fdbe80c685971febe72f3 169 Gene3D G3DSA:3.10.450.50 26 136 1.9E-9 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS09725 b24e88feb68fdbe80c685971febe72f3 169 SUPERFAMILY SSF54427 21 143 3.1E-20 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS02650 76afcef500b00307883262a91d270d88 236 Pfam PF13488 Glycine zipper 39 86 1.8E-7 T 22-04-2016 MED134_RS02650 76afcef500b00307883262a91d270d88 236 Gene3D G3DSA:3.30.1330.60 109 220 7.5E-39 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS02650 76afcef500b00307883262a91d270d88 236 PRINTS PR01021 OMPA domain signature 163 179 3.7E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02650 76afcef500b00307883262a91d270d88 236 PRINTS PR01021 OMPA domain signature 148 163 3.7E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02650 76afcef500b00307883262a91d270d88 236 PRINTS PR01021 OMPA domain signature 118 140 3.7E-13 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02650 76afcef500b00307883262a91d270d88 236 SUPERFAMILY SSF103088 98 217 3.27E-38 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS02650 76afcef500b00307883262a91d270d88 236 PANTHER PTHR30128 41 224 2.0E-41 T 22-04-2016 MED134_RS02650 76afcef500b00307883262a91d270d88 236 Pfam PF00691 OmpA family 117 212 7.3E-25 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS10455 dc46872ac1fd56e1cde700c07a91800a 224 SUPERFAMILY SSF51569 5 217 3.3E-51 T 22-04-2016 MED134_RS10455 dc46872ac1fd56e1cde700c07a91800a 224 Pfam PF01081 KDPG and KHG aldolase 10 197 1.3E-27 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MED134_RS10455 dc46872ac1fd56e1cde700c07a91800a 224 Gene3D G3DSA:3.20.20.70 4 222 5.3E-59 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS10455 dc46872ac1fd56e1cde700c07a91800a 224 PANTHER PTHR30246:SF4 1 224 1.4E-64 T 22-04-2016 MED134_RS10455 dc46872ac1fd56e1cde700c07a91800a 224 PANTHER PTHR30246 1 224 1.4E-64 T 22-04-2016 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 Gene3D G3DSA:3.40.640.10 46 271 7.2E-71 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 SUPERFAMILY SSF53383 4 373 3.38E-98 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 Gene3D G3DSA:3.90.1150.10 272 372 1.7E-24 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 PANTHER PTHR11986:SF79 1 374 7.1E-119 T 22-04-2016 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 PANTHER PTHR11986 1 374 7.1E-119 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS11755 423cba85ce2c1da83ff83b4d6592c04c 374 Pfam PF00202 Aminotransferase class-III 12 372 6.9E-87 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 Pfam PF02590 Predicted SPOUT methyltransferase 1 155 6.9E-52 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 PANTHER PTHR33603:SF1 1 156 5.5E-57 T 22-04-2016 MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 156 26.378 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 SUPERFAMILY SSF75217 1 155 1.88E-48 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 PIRSF PIRSF004505 1 156 6.5E-49 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 Gene3D G3DSA:3.40.1280.10 1 156 5.0E-55 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS02255 3deb1923967e23edde0d5e908a2095c3 157 PANTHER PTHR33603 1 156 5.5E-57 T 22-04-2016 MED134_RS03110 57c0b0be9b587dc6b44f83d7c995b382 147 SUPERFAMILY SSF52833 22 132 1.08E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS03110 57c0b0be9b587dc6b44f83d7c995b382 147 Pfam PF13899 Thioredoxin-like 23 117 1.3E-16 T 22-04-2016 MED134_RS03110 57c0b0be9b587dc6b44f83d7c995b382 147 Gene3D G3DSA:3.40.30.10 20 144 1.5E-24 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 SUPERFAMILY SSF53649 3 76 2.75E-73 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 SUPERFAMILY SSF53649 306 501 2.75E-73 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Gene3D G3DSA:3.40.720.10 310 503 7.6E-86 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Gene3D G3DSA:3.40.720.10 3 76 7.6E-86 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 81 294 6.7E-79 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 PANTHER PTHR31637:SF0 1 504 2.8E-247 T 22-04-2016 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Pfam PF01676 Metalloenzyme superfamily 3 493 5.9E-77 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Gene3D G3DSA:3.40.1450.10 77 306 1.7E-86 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 SUPERFAMILY SSF64158 76 298 4.58E-74 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 PANTHER PTHR31637 1 504 2.8E-247 T 22-04-2016 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 3 504 46.219 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 PIRSF PIRSF001492 1 504 7.6E-204 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS06940 e1bfc1b1e6a7960f7ac30f303bb7bb6f 504 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 3 503 1.2E-201 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 PIRSF PIRSF000190 1 214 1.9E-75 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 SUPERFAMILY SSF50475 21 214 7.24E-65 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 PANTHER PTHR10851:SF0 1 214 6.9E-103 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 4 214 2.2E-88 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 Gene3D G3DSA:2.30.110.10 19 214 4.7E-79 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 120 1.3E-20 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 184 197 - T 22-04-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 174 214 3.3E-21 T 22-04-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 PANTHER PTHR10851 1 214 6.9E-103 T 22-04-2016 MED134_RS00995 f62fe058235e27033cbc8dca11be50d9 214 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 11 214 37.124 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 870 156.806 T 22-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PANTHER PTHR11777 1 870 0.0 T 22-04-2016 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 652 694 1.2E-16 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 234 247 2.6E-30 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 284 300 2.6E-30 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 2.6E-30 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 207 218 2.6E-30 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 308 321 2.6E-30 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 SUPERFAMILY SSF50447 459 537 4.94E-14 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 SUPERFAMILY SSF55186 550 706 5.1E-44 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 SMART SM00863 652 694 2.2E-19 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 Pfam PF02272 DHHA1 domain 796 866 8.2E-9 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 Gene3D G3DSA:3.30.930.10 1 249 8.7E-113 T 22-04-2016 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 SUPERFAMILY SSF101353 254 469 2.22E-65 T 22-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 Pfam PF01411 tRNA synthetases class II (A) 5 538 6.6E-201 T 22-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 SUPERFAMILY SSF55681 2 253 9.69E-99 T 22-04-2016 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 PANTHER PTHR11777:SF9 1 870 0.0 T 22-04-2016 MED134_RS11455 c07be77c9fb7472439e30dca9662e39a 870 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 852 3.9E-276 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 MED134_RS13890 2343778cdd604a0109db4998df22af5a 182 Pfam PF01713 Smr domain 118 175 1.6E-5 T 22-04-2016 IPR002625 Smr domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PANTHER PTHR24078:SF190 1 373 9.0E-124 T 22-04-2016 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PRINTS PR00625 DnaJ domain signature 6 24 1.3E-30 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PRINTS PR00625 DnaJ domain signature 24 39 1.3E-30 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PRINTS PR00625 DnaJ domain signature 41 61 1.3E-30 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PRINTS PR00625 DnaJ domain signature 61 80 1.3E-30 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 373 32.845 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SMART SM00271 3 61 6.2E-30 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SUPERFAMILY SSF57938 158 200 1.83E-9 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Pfam PF01556 DnaJ C terminal domain 128 335 7.9E-39 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SUPERFAMILY SSF46565 3 111 2.22E-35 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Pfam PF00226 DnaJ domain 4 66 2.3E-27 T 22-04-2016 IPR001623 DnaJ domain MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Gene3D G3DSA:2.10.230.10 156 203 5.2E-12 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 22-04-2016 IPR018253 DnaJ domain, conserved site MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SUPERFAMILY SSF49493 120 167 1.11E-16 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SUPERFAMILY SSF49493 261 346 8.24E-24 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 PANTHER PTHR24078 1 373 9.0E-124 T 22-04-2016 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Gene3D G3DSA:2.60.260.20 258 336 1.7E-22 T 22-04-2016 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 SUPERFAMILY SSF49493 215 266 1.11E-16 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Gene3D G3DSA:2.60.260.20 115 154 6.7E-19 T 22-04-2016 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Gene3D G3DSA:2.60.260.20 211 256 6.7E-19 T 22-04-2016 MED134_RS13205 2531b0e240be2929ec4a813f5f8e8aff 375 Gene3D G3DSA:1.10.287.110 1 102 7.8E-36 T 22-04-2016 IPR001623 DnaJ domain MED134_RS06945 3b5c73dd2853505693fe9774a12d6940 210 Pfam PF14595 Thioredoxin 86 189 3.3E-7 T 22-04-2016 MED134_RS06945 3b5c73dd2853505693fe9774a12d6940 210 Gene3D G3DSA:3.40.30.10 84 199 8.0E-19 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06945 3b5c73dd2853505693fe9774a12d6940 210 SUPERFAMILY SSF52833 95 201 2.9E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS07100 1749a34bfacad5236fab2a70fea5809c 323 Pfam PF00561 alpha/beta hydrolase fold 35 151 3.4E-18 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS07100 1749a34bfacad5236fab2a70fea5809c 323 Gene3D G3DSA:3.40.50.1820 19 308 4.2E-19 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS07100 1749a34bfacad5236fab2a70fea5809c 323 PIRSF PIRSF000443 2 323 5.4E-55 T 22-04-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 MED134_RS07100 1749a34bfacad5236fab2a70fea5809c 323 SUPERFAMILY SSF53474 23 314 2.98E-58 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS07100 1749a34bfacad5236fab2a70fea5809c 323 PANTHER PTHR32268 35 313 4.0E-40 T 22-04-2016 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Gene3D G3DSA:3.30.70.1450 155 225 4.2E-5 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PANTHER PTHR13789 1 449 8.1E-33 T 22-04-2016 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PRINTS PR00335 TrkA potassium uptake protein signature 293 303 4.8E-14 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PRINTS PR00335 TrkA potassium uptake protein signature 306 320 4.8E-14 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.8E-14 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.8E-14 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PRINTS PR00335 TrkA potassium uptake protein signature 282 292 4.8E-14 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 PANTHER PTHR13789:SF225 1 449 8.1E-33 T 22-04-2016 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 SUPERFAMILY SSF116726 137 226 4.71E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Gene3D G3DSA:3.40.50.720 233 374 2.6E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Gene3D G3DSA:3.40.50.720 1 149 1.0E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 SUPERFAMILY SSF51735 1 149 1.34E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Pfam PF02254 TrkA-N domain 3 123 2.7E-22 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Pfam PF02254 TrkA-N domain 235 350 7.8E-22 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Pfam PF02080 TrkA-C domain 382 448 1.0E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Pfam PF02080 TrkA-C domain 162 225 8.2E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 SUPERFAMILY SSF116726 362 448 1.83E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 SUPERFAMILY SSF51735 233 374 4.04E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05485 979cc8255336e99d05d58f1891b9270e 449 Gene3D G3DSA:3.30.70.1450 380 447 2.6E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MED134_RS12730 a386751c250c038391d0308b6b78c552 150 PANTHER PTHR11803:SF1 26 144 4.9E-46 T 22-04-2016 MED134_RS12730 a386751c250c038391d0308b6b78c552 150 SUPERFAMILY SSF55298 20 147 5.18E-33 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS12730 a386751c250c038391d0308b6b78c552 150 Gene3D G3DSA:3.30.1330.40 18 147 1.7E-38 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MED134_RS12730 a386751c250c038391d0308b6b78c552 150 Pfam PF01042 Endoribonuclease L-PSP 19 145 1.6E-28 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS12730 a386751c250c038391d0308b6b78c552 150 PANTHER PTHR11803 26 144 4.9E-46 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family MED134_RS08860 0856fb183ed5f76d180cbb1ec07d7598 196 PANTHER PTHR35446 1 190 9.1E-16 T 22-04-2016 MED134_RS08860 0856fb183ed5f76d180cbb1ec07d7598 196 SUPERFAMILY SSF69118 9 176 3.29E-39 T 22-04-2016 IPR029032 AhpD-like MED134_RS08860 0856fb183ed5f76d180cbb1ec07d7598 196 Gene3D G3DSA:1.20.1290.10 30 175 1.4E-33 T 22-04-2016 IPR029032 AhpD-like MED134_RS08860 0856fb183ed5f76d180cbb1ec07d7598 196 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 120 1.5E-10 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 Pfam PF12833 Helix-turn-helix domain 203 281 1.5E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 Pfam PF02311 AraC-like ligand binding domain 26 80 8.6E-6 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 Gene3D G3DSA:1.10.10.60 174 232 1.6E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 Gene3D G3DSA:2.60.120.280 19 89 6.7E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 Gene3D G3DSA:1.10.10.60 237 283 5.0E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 SUPERFAMILY SSF51215 27 136 2.35E-9 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 SUPERFAMILY SSF46689 233 282 1.66E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 PANTHER PTHR11019 29 144 5.6E-31 T 22-04-2016 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 PANTHER PTHR11019 164 288 5.6E-31 T 22-04-2016 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 SMART SM00342 196 280 1.1E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 2.7E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS00075 8373c06fb52aba40a7d3fd99f0ef6fee 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 2.7E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 PANTHER PTHR22769:SF42 1 139 1.2E-18 T 22-04-2016 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 Pfam PF00293 NUDIX domain 36 118 6.1E-13 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 PANTHER PTHR22769 1 139 1.2E-18 T 22-04-2016 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 SUPERFAMILY SSF55811 8 142 5.55E-18 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS05705 b75b4dcf0fa88f73b020f8dea5eaf2d1 171 Gene3D G3DSA:3.90.79.10 32 142 1.8E-16 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS12530 aa17101b26c940f4866264251d450299 365 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 144 1.4E-31 T 22-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12530 aa17101b26c940f4866264251d450299 365 PANTHER PTHR21015 2 364 2.9E-117 T 22-04-2016 MED134_RS12530 aa17101b26c940f4866264251d450299 365 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 361 31.772 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12530 aa17101b26c940f4866264251d450299 365 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 355 2.1E-87 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12530 aa17101b26c940f4866264251d450299 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 193 318 2.7E-33 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 MED134_RS12530 aa17101b26c940f4866264251d450299 365 PANTHER PTHR21015:SF22 2 364 2.9E-117 T 22-04-2016 MED134_RS12530 aa17101b26c940f4866264251d450299 365 SUPERFAMILY SSF53756 5 362 1.17E-103 T 22-04-2016 MED134_RS12530 aa17101b26c940f4866264251d450299 365 Gene3D G3DSA:3.40.50.2000 4 205 4.7E-62 T 22-04-2016 MED134_RS14190 6eed05491b01a1b058e720f232e688ad 459 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 20 451 4.5E-167 T 22-04-2016 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90 MED134_RS14190 6eed05491b01a1b058e720f232e688ad 459 PANTHER PTHR12639 18 451 4.5E-93 T 22-04-2016 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90 MED134_RS14190 6eed05491b01a1b058e720f232e688ad 459 PANTHER PTHR12639:SF7 18 451 4.5E-93 T 22-04-2016 MED134_RS14190 6eed05491b01a1b058e720f232e688ad 459 SMART SM00752 10 273 5.3E-87 T 22-04-2016 IPR011020 HTTM MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 22-04-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 Pfam PF01016 Ribosomal L27 protein 2 81 4.3E-35 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 6.7E-33 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 Gene3D G3DSA:2.40.50.100 20 84 1.3E-29 T 22-04-2016 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 25.982 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.0E-32 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.0E-32 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.0E-32 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 84 2.0E-12 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 PANTHER PTHR15893 1 85 1.7E-40 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06000 322c1c9edf55e7cae6e1d1c0fad62490 86 SUPERFAMILY SSF110324 2 83 1.22E-32 T 22-04-2016 MED134_RS13405 281597236a4bdace41bd7b5fdd13ebdc 315 Pfam PF00535 Glycosyl transferase family 2 21 146 7.6E-27 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13405 281597236a4bdace41bd7b5fdd13ebdc 315 Gene3D G3DSA:3.90.550.10 16 146 6.4E-33 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13405 281597236a4bdace41bd7b5fdd13ebdc 315 PANTHER PTHR22916:SF2 1 134 1.2E-32 T 22-04-2016 MED134_RS13405 281597236a4bdace41bd7b5fdd13ebdc 315 SUPERFAMILY SSF53448 18 222 6.08E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13405 281597236a4bdace41bd7b5fdd13ebdc 315 PANTHER PTHR22916 1 134 1.2E-32 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 Pfam PF14821 Threonine synthase N terminus 2 78 1.2E-18 T 22-04-2016 IPR029144 Threonine synthase, N-terminal MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 Gene3D G3DSA:3.90.1380.10 1 85 3.3E-23 T 22-04-2016 IPR029144 Threonine synthase, N-terminal MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 97 111 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 Gene3D G3DSA:3.40.50.1100 106 201 8.6E-14 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 PANTHER PTHR10314:SF1 53 426 2.6E-112 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 PANTHER PTHR10314:SF1 25 36 2.6E-112 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 PANTHER PTHR10314 53 426 2.6E-112 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 PANTHER PTHR10314 25 36 2.6E-112 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 Gene3D G3DSA:3.40.50.1100 202 408 3.9E-64 T 22-04-2016 MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 SUPERFAMILY SSF53686 1 432 8.79E-123 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 98 370 1.2E-23 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS00110 2f50e0293da42ada41fccb9359ab4806 433 TIGRFAM TIGR00260 thrC: threonine synthase 60 399 2.6E-82 T 22-04-2016 IPR004450 Threonine synthase-like MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 PANTHER PTHR12053:SF3 192 487 7.0E-43 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 PANTHER PTHR12053:SF3 24 158 7.0E-43 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 Gene3D G3DSA:3.40.630.10 277 482 2.7E-60 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 Gene3D G3DSA:3.40.630.10 34 92 2.7E-60 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 SUPERFAMILY SSF53187 261 481 6.29E-57 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 SUPERFAMILY SSF53187 38 80 6.29E-57 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 Pfam PF04389 Peptidase family M28 278 466 3.2E-32 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 PANTHER PTHR12053 192 487 7.0E-43 T 22-04-2016 MED134_RS01110 9976fbcb856c6ae8d0973cc5e56b9c2c 516 PANTHER PTHR12053 24 158 7.0E-43 T 22-04-2016 MED134_RS04045 1cd390b1e862c554625946c63231079d 200 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 159 1.3E-11 T 22-04-2016 MED134_RS04045 1cd390b1e862c554625946c63231079d 200 SUPERFAMILY SSF51735 1 199 2.4E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04045 1cd390b1e862c554625946c63231079d 200 Gene3D G3DSA:3.40.50.720 1 199 7.2E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 Pfam PF12796 Ankyrin repeats (3 copies) 977 1067 1.0E-6 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SUPERFAMILY SSF48403 846 1091 3.22E-32 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 Gene3D G3DSA:1.25.40.20 607 903 9.8E-18 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 Gene3D G3DSA:1.25.40.20 904 1092 1.0E-29 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 783 812 47.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 864 893 410.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 675 704 2300.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 1039 1070 9.1 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 452 481 910.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 537 566 3000.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 594 623 95.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 1003 1035 0.01 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SMART SM00248 943 972 36.0 T 22-04-2016 IPR002110 Ankyrin repeat GO:0005515 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 Gene3D G3DSA:1.25.40.20 455 606 3.4E-4 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 PANTHER PTHR24198 756 811 7.6E-25 T 22-04-2016 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 PANTHER PTHR24198 836 897 7.6E-25 T 22-04-2016 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 PANTHER PTHR24198 918 1081 7.6E-25 T 22-04-2016 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 PANTHER PTHR24198 407 419 7.6E-25 T 22-04-2016 MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 Pfam PF01823 MAC/Perforin domain 110 258 3.5E-9 T 22-04-2016 IPR020864 Membrane attack complex component/perforin (MACPF) domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SUPERFAMILY SSF48403 707 902 2.8E-11 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS03775 ef0e90be1f8a01dfcfb0f30dcb892667 1102 SUPERFAMILY SSF48403 442 622 3.88E-6 T 22-04-2016 IPR020683 Ankyrin repeat-containing domain MED134_RS12685 d62d54c36cb575baca1c3cf2e9a234f5 93 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 5 84 16.099 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MED134_RS12685 d62d54c36cb575baca1c3cf2e9a234f5 93 Pfam PF02416 mttA/Hcf106 family 8 58 5.6E-15 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 722 792 1.1E-11 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 PANTHER PTHR11705:SF56 73 415 2.5E-47 T 22-04-2016 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 PANTHER PTHR11705 73 415 2.5E-47 T 22-04-2016 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 Pfam PF05547 Immune inhibitor A peptidase M6 582 703 2.3E-16 T 22-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 Pfam PF00246 Zinc carboxypeptidase 167 423 5.7E-46 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 SUPERFAMILY SSF53187 124 433 8.38E-63 T 22-04-2016 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 SMART SM00631 127 421 2.4E-36 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS01915 cffd4b272ff04e562768c2863f8ae253 792 Gene3D G3DSA:3.40.630.10 125 434 1.3E-75 T 22-04-2016 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 Gene3D G3DSA:3.90.1150.10 275 395 8.6E-31 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 PANTHER PTHR11751 11 396 9.1E-156 T 22-04-2016 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 Pfam PF00155 Aminotransferase class I and II 35 384 6.6E-54 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 SUPERFAMILY SSF53383 1 394 7.1E-98 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 Gene3D G3DSA:3.40.640.10 45 274 6.0E-69 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 PANTHER PTHR11751:SF404 11 396 9.1E-156 T 22-04-2016 MED134_RS05820 ae3332f05bd172ed34ea9ce29eb11d55 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Pfam PF03308 ArgK protein 167 414 3.3E-42 T 22-04-2016 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 SUPERFAMILY SSF52540 126 455 2.75E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Pfam PF02310 B12 binding domain 14 116 1.2E-10 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Gene3D G3DSA:3.40.50.280 9 141 2.0E-37 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 PANTHER PTHR23408:SF1 773 1141 6.6E-217 T 22-04-2016 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 PANTHER PTHR23408:SF1 486 708 6.6E-217 T 22-04-2016 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 SUPERFAMILY SSF52242 5 144 6.41E-42 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Gene3D G3DSA:3.40.50.300 197 398 3.5E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Gene3D G3DSA:3.20.20.240 772 1137 7.2E-191 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Gene3D G3DSA:3.20.20.240 567 707 7.2E-191 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 PANTHER PTHR23408 773 1141 6.6E-217 T 22-04-2016 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 PANTHER PTHR23408 486 708 6.6E-217 T 22-04-2016 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 Pfam PF01642 Methylmalonyl-CoA mutase 577 1135 1.6E-131 T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 SUPERFAMILY SSF51703 772 1137 1.39E-138 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 MED134_RS03735 b70810a1b8e4276bcc0c415fe2020b0c 1141 SUPERFAMILY SSF51703 561 707 1.39E-138 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 SUPERFAMILY SSF111369 51 253 2.35E-14 T 22-04-2016 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 Gene3D G3DSA:2.40.50.100 60 93 1.0E-13 T 22-04-2016 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 Gene3D G3DSA:2.40.50.100 189 213 1.0E-13 T 22-04-2016 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 PANTHER PTHR32347:SF12 6 372 1.7E-42 T 22-04-2016 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 274 2.3E-15 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 374 4.7E-35 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 PANTHER PTHR32347 6 372 1.7E-42 T 22-04-2016 MED134_RS11390 b89b8f13b0e926692bbed5facc329402 388 Gene3D G3DSA:1.20.1600.10 106 172 1.0E-5 T 22-04-2016 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Gene3D G3DSA:3.40.50.670 414 629 2.1E-92 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 SUPERFAMILY SSF55874 9 217 5.5E-71 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 576 637 5.0E-29 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 SMART SM00387 35 179 9.3E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 ProSitePatterns PS00177 DNA topoisomerase II signature. 432 440 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 SUPERFAMILY SSF56719 404 639 2.88E-87 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Gene3D G3DSA:3.30.565.10 10 218 2.7E-88 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 177 5.4E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 SMART SM00433 39 641 0.0 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 117 131 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 539 551 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 39 54 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 519 536 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 501 517 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 278 291 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 74 87 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 580 596 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR00418 DNA topoisomerase II family signature 430 444 3.5E-69 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 643 8.8E-285 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PANTHER PTHR10169 1 640 6.8E-279 T 22-04-2016 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 252 270 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 185 200 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 384 404 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 200 213 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 10 20 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 617 633 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 322 338 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 370 384 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 480 489 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 PRINTS PR01159 DNA gyrase subunit B signature 601 613 1.7E-65 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Pfam PF01751 Toprim domain 429 544 5.9E-18 T 22-04-2016 IPR006171 Toprim domain MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 647 85.14 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Pfam PF00204 DNA gyrase B 231 400 1.1E-59 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 SUPERFAMILY SSF54211 231 401 2.66E-57 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS12790 5ff30d05a0c32a0e5a82253fbe4759da 647 Gene3D G3DSA:3.30.230.10 230 402 3.2E-69 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 26 467 6.3E-164 T 22-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 SMART SM00382 217 418 1.6E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 Pfam PF00772 DnaB-like helicase N terminal domain 26 126 6.5E-32 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 Gene3D G3DSA:3.40.50.300 190 467 5.6E-95 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 SUPERFAMILY SSF52540 198 458 8.09E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 PANTHER PTHR30153 10 475 4.0E-195 T 22-04-2016 MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 SUPERFAMILY SSF48024 24 136 3.66E-31 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 Pfam PF03796 DnaB-like helicase C terminal domain 200 465 2.4E-106 T 22-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 MED134_RS05755 d62153f4b667053816ef00ec549d1154 518 Gene3D G3DSA:1.10.860.10 26 128 3.0E-33 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 PANTHER PTHR21091 5 340 1.5E-147 T 22-04-2016 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 340 7.5E-135 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 PANTHER PTHR21091:SF2 5 340 1.5E-147 T 22-04-2016 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 21 30 - T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 Gene3D G3DSA:3.20.20.210 4 341 8.3E-148 T 22-04-2016 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 5 341 46.28 T 22-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 339 1.6E-131 T 22-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08680 baac40854837b0623055eeb3c3074d24 342 SUPERFAMILY SSF51726 3 341 1.96E-119 T 22-04-2016 MED134_RS08815 8230139ba977ca02ac1580a0e71380c3 244 Pfam PF01553 Acyltransferase 64 188 3.8E-24 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS08815 8230139ba977ca02ac1580a0e71380c3 244 SMART SM00563 77 192 3.1E-24 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS08815 8230139ba977ca02ac1580a0e71380c3 244 Gene3D G3DSA:3.40.1130.10 65 213 1.3E-23 T 22-04-2016 MED134_RS08815 8230139ba977ca02ac1580a0e71380c3 244 SUPERFAMILY SSF69593 13 241 4.45E-33 T 22-04-2016 MED134_RS08815 8230139ba977ca02ac1580a0e71380c3 244 PANTHER PTHR10434 1 242 3.6E-43 T 22-04-2016 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 SUPERFAMILY SSF55874 352 466 2.1E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 Pfam PF00672 HAMP domain 171 239 1.3E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 SMART SM00387 360 466 1.3E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 Gene3D G3DSA:3.30.565.10 311 466 3.1E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 Gene3D G3DSA:1.10.287.130 247 310 1.4E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 319 1.5E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PANTHER PTHR24423 184 466 8.5E-47 T 22-04-2016 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PANTHER PTHR24423 22 38 8.5E-47 T 22-04-2016 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 SMART SM00388 253 324 1.3E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 465 2.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 2.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 2.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 2.8E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 465 1.5E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS08625 c2c0750d1ddf80d40eaafdf1de1be81b 466 SUPERFAMILY SSF47384 246 323 1.22E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 Pfam PF01687 Riboflavin kinase 184 304 2.6E-33 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 Gene3D G3DSA:2.40.30.30 179 312 1.3E-39 T 22-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 Gene3D G3DSA:3.40.50.620 7 178 1.3E-59 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 SUPERFAMILY SSF52374 14 174 1.1E-35 T 22-04-2016 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 306 3.5E-77 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 PANTHER PTHR22749:SF0 11 306 1.4E-112 T 22-04-2016 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 SUPERFAMILY SSF82114 173 309 1.37E-42 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 Pfam PF06574 FAD synthetase 11 165 9.8E-49 T 22-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 SMART SM00904 182 307 1.2E-51 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 PANTHER PTHR22749 11 306 1.4E-112 T 22-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 MED134_RS08290 90d05fbda55d6c427c8a45485f508460 317 PIRSF PIRSF004491 1 314 1.3E-105 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 Gene3D G3DSA:3.40.50.720 7 186 1.1E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 PANTHER PTHR10366 13 332 7.9E-102 T 22-04-2016 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 254 3.2E-56 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 PANTHER PTHR10366:SF472 13 332 7.9E-102 T 22-04-2016 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 Gene3D G3DSA:3.90.25.10 187 316 3.3E-32 T 22-04-2016 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 SUPERFAMILY SSF51735 8 330 9.93E-91 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 PRINTS PR01713 Nucleotide sugar epimerase signature 223 238 1.4E-9 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 PRINTS PR01713 Nucleotide sugar epimerase signature 293 310 1.4E-9 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS01330 7230a5b6387c38c28ef9b18bd0981003 332 PRINTS PR01713 Nucleotide sugar epimerase signature 248 263 1.4E-9 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 233 2.5E-75 T 22-04-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 PANTHER PTHR21235 1 238 5.2E-96 T 22-04-2016 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 237 32.556 T 22-04-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 PANTHER PTHR21235:SF15 1 238 5.2E-96 T 22-04-2016 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 Gene3D G3DSA:3.20.20.70 1 237 3.3E-83 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 Pfam PF00977 Histidine biosynthesis protein 2 230 1.1E-69 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 MED134_RS02425 e647687e2ae736f50a477bcfbdab51ad 240 SUPERFAMILY SSF51366 1 237 1.41E-65 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS01675 6a633d434b8c55d5b0294daa2873bcfc 366 PANTHER PTHR41519:SF1 31 365 1.3E-26 T 22-04-2016 MED134_RS01675 6a633d434b8c55d5b0294daa2873bcfc 366 Pfam PF13449 Esterase-like activity of phytase 53 350 3.8E-70 T 22-04-2016 IPR027372 Phytase-like domain MED134_RS01675 6a633d434b8c55d5b0294daa2873bcfc 366 PANTHER PTHR41519 31 365 1.3E-26 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82866 317 517 3.01E-41 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Gene3D G3DSA:3.30.70.1430 55 127 1.6E-17 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Gene3D G3DSA:1.10.3850.10 908 1159 6.2E-51 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82693 292 352 4.71E-8 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82693 160 197 4.71E-8 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Gene3D G3DSA:3.30.2090.10 814 901 2.9E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Gene3D G3DSA:3.30.2090.10 198 279 3.7E-12 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82714 199 279 1.7E-11 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82714 815 885 9.29E-8 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Pfam PF00873 AcrB/AcrD/AcrF family 16 529 5.2E-93 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Pfam PF00873 AcrB/AcrD/AcrF family 581 1157 4.2E-59 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PRINTS PR00702 Acriflavin resistance protein family signature 491 514 1.54E-27 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.54E-27 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PRINTS PR00702 Acriflavin resistance protein family signature 358 381 1.54E-27 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PRINTS PR00702 Acriflavin resistance protein family signature 412 436 1.54E-27 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PRINTS PR00702 Acriflavin resistance protein family signature 50 68 1.54E-27 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82693 53 127 3.66E-16 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PANTHER PTHR32063 13 524 6.4E-239 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PANTHER PTHR32063 568 1102 6.4E-239 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 PANTHER PTHR32063 1121 1165 6.4E-239 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 SUPERFAMILY SSF82866 902 1162 5.62E-37 T 22-04-2016 MED134_RS07380 369f616f70002fa8a5ee4466ee6a9dc1 1181 Gene3D G3DSA:1.20.1640.10 312 523 4.6E-48 T 22-04-2016 MED134_RS13195 d5511f9b5fad1a7a2c160970e39974bd 221 Pfam PF04264 YceI-like domain 46 218 1.6E-25 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13195 d5511f9b5fad1a7a2c160970e39974bd 221 Gene3D G3DSA:2.40.128.110 45 220 9.8E-35 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13195 d5511f9b5fad1a7a2c160970e39974bd 221 SMART SM00867 45 219 7.8E-26 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13195 d5511f9b5fad1a7a2c160970e39974bd 221 SUPERFAMILY SSF101874 45 220 5.75E-33 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS02005 5eded24887237aea1d61d7110571dd8a 823 Pfam PF06452 Carbohydrate family 9 binding domain-like 36 181 5.4E-5 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS02005 5eded24887237aea1d61d7110571dd8a 823 Gene3D G3DSA:2.60.40.1190 27 205 1.8E-26 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS02005 5eded24887237aea1d61d7110571dd8a 823 SUPERFAMILY SSF49344 26 224 3.14E-39 T 22-04-2016 MED134_RS01530 883aeafe8f30ee54ae0afc7de208b8ac 190 PANTHER PTHR24567 10 189 1.2E-31 T 22-04-2016 MED134_RS01530 883aeafe8f30ee54ae0afc7de208b8ac 190 Gene3D G3DSA:2.60.120.10 3 154 2.8E-34 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS01530 883aeafe8f30ee54ae0afc7de208b8ac 190 SUPERFAMILY SSF51206 8 117 3.01E-18 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS01530 883aeafe8f30ee54ae0afc7de208b8ac 190 Pfam PF00027 Cyclic nucleotide-binding domain 28 117 1.3E-9 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS01530 883aeafe8f30ee54ae0afc7de208b8ac 190 PANTHER PTHR24567:SF33 10 189 1.2E-31 T 22-04-2016 MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 SUPERFAMILY SSF52540 81 464 2.91E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 Gene3D G3DSA:3.40.50.300 202 468 1.7E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 PANTHER PTHR30258:SF1 94 464 2.2E-154 T 22-04-2016 MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 Gene3D G3DSA:3.30.450.90 79 195 5.0E-41 T 22-04-2016 MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 SMART SM00382 224 345 0.0015 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 PANTHER PTHR30258 94 464 2.2E-154 T 22-04-2016 MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 291 305 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MED134_RS08365 eb5f649e9c8057f520e561a9f4b0b1f1 470 Pfam PF00437 Type II/IV secretion system protein 106 363 1.0E-76 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MED134_RS10115 cca5252ffd26b2435fccc90920a811fc 313 PANTHER PTHR33608:SF2 14 310 1.6E-66 T 22-04-2016 MED134_RS10115 cca5252ffd26b2435fccc90920a811fc 313 SUPERFAMILY SSF53300 76 253 1.33E-22 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS10115 cca5252ffd26b2435fccc90920a811fc 313 PANTHER PTHR33608 14 310 1.6E-66 T 22-04-2016 MED134_RS10115 cca5252ffd26b2435fccc90920a811fc 313 Pfam PF01882 Protein of unknown function DUF58 42 131 1.6E-15 T 22-04-2016 IPR002881 Domain of unknown function DUF58 MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 PANTHER PTHR12151 11 209 1.4E-33 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 SUPERFAMILY SSF52833 58 217 1.41E-35 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 Pfam PF02630 SCO1/SenC 59 199 4.4E-16 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 PANTHER PTHR12151:SF10 11 209 1.4E-33 T 22-04-2016 MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 Gene3D G3DSA:3.40.30.10 15 21 1.5E-40 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10550 5212e21880193e3f5f4b76d78e94405e 220 Gene3D G3DSA:3.40.30.10 53 218 1.5E-40 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 SMART SM00175 6 164 1.1E-12 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PANTHER PTHR24073 1 164 1.0E-36 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 157 1.5E-22 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 Gene3D G3DSA:3.40.50.300 6 164 4.6E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 SMART SM00174 7 165 2.6E-7 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PRINTS PR00449 Transforming protein P21 ras signature 139 161 3.4E-26 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PRINTS PR00449 Transforming protein P21 ras signature 5 26 3.4E-26 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PRINTS PR00449 Transforming protein P21 ras signature 47 69 3.4E-26 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PRINTS PR00449 Transforming protein P21 ras signature 28 44 3.4E-26 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 PRINTS PR00449 Transforming protein P21 ras signature 108 121 3.4E-26 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 SUPERFAMILY SSF52540 5 163 7.26E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 SMART SM00173 2 164 2.7E-9 T 22-04-2016 MED134_RS08170 f1202f7bda25a2ea8e3b01e5beea02a5 165 Pfam PF00071 Ras family 6 162 1.0E-33 T 22-04-2016 IPR001806 Small GTPase superfamily GO:0005525|GO:0007264 MED134_RS08850 91a35cc4faeb313305dfaabfe7f907a9 149 Pfam PF02566 OsmC-like protein 36 134 1.9E-16 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS08850 91a35cc4faeb313305dfaabfe7f907a9 149 Gene3D G3DSA:3.30.300.20 43 138 1.9E-30 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS08850 91a35cc4faeb313305dfaabfe7f907a9 149 SUPERFAMILY SSF82784 4 136 2.22E-29 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS08850 91a35cc4faeb313305dfaabfe7f907a9 149 PANTHER PTHR34352 1 142 7.6E-28 T 22-04-2016 MED134_RS08850 91a35cc4faeb313305dfaabfe7f907a9 149 Gene3D G3DSA:2.20.25.10 10 40 1.8E-6 T 22-04-2016 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 Gene3D G3DSA:3.60.150.10 9 350 8.0E-158 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 TIGRFAM TIGR00033 aroC: chorismate synthase 10 351 1.2E-139 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 PIRSF PIRSF001456 3 353 1.9E-145 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 37.071 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 SUPERFAMILY SSF103263 4 350 4.06E-138 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 PANTHER PTHR21085 2 348 1.3E-205 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 ProSitePatterns PS00789 Chorismate synthase signature 3. 321 337 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS03550 bf5e977e4146b80b95b457f294fdc7cb 354 Pfam PF01264 Chorismate synthase 10 347 2.3E-144 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS07295 ab02873405ccad577d72d509976f66c9 219 Pfam PF09365 Conserved hypothetical protein (DUF2461) 6 210 1.7E-57 T 22-04-2016 IPR012808 Conserved hypothetical protein CHP02453 MED134_RS07295 ab02873405ccad577d72d509976f66c9 219 PANTHER PTHR36452 5 217 7.0E-30 T 22-04-2016 MED134_RS07295 ab02873405ccad577d72d509976f66c9 219 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 5 215 2.0E-48 T 22-04-2016 IPR012808 Conserved hypothetical protein CHP02453 MED134_RS07295 ab02873405ccad577d72d509976f66c9 219 PANTHER PTHR36452:SF1 5 217 7.0E-30 T 22-04-2016 MED134_RS07295 ab02873405ccad577d72d509976f66c9 219 PIRSF PIRSF028451 1 219 2.4E-48 T 22-04-2016 IPR015996 Uncharacterised conserved protein UCP028451 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 SUPERFAMILY SSF51556 71 336 1.83E-37 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 Gene3D G3DSA:2.30.40.10 18 73 1.1E-20 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 Gene3D G3DSA:2.30.40.10 338 377 1.1E-20 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 PANTHER PTHR11271 22 378 8.4E-30 T 22-04-2016 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 SUPERFAMILY SSF51338 19 72 7.92E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 SUPERFAMILY SSF51338 338 370 7.92E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 Pfam PF01979 Amidohydrolase family 68 374 3.5E-13 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 Gene3D G3DSA:3.20.20.140 74 333 5.4E-39 T 22-04-2016 MED134_RS00930 ce1f1fee57ec013d9123da4a6ad7343b 378 PANTHER PTHR11271:SF33 22 378 8.4E-30 T 22-04-2016 MED134_RS05065 55ff8841467419901e1f7fcae8c02617 165 PANTHER PTHR37953:SF1 53 161 1.5E-19 T 22-04-2016 MED134_RS05065 55ff8841467419901e1f7fcae8c02617 165 Pfam PF02643 Uncharacterized ACR, COG1430 56 161 3.5E-23 T 22-04-2016 IPR003795 Protein of unknown function DUF192 MED134_RS05065 55ff8841467419901e1f7fcae8c02617 165 PANTHER PTHR37953 53 161 1.5E-19 T 22-04-2016 MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 6 213 34.477 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 11 211 7.8E-56 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 SUPERFAMILY SSF53335 17 202 6.62E-38 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 135 150 - T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 211 6.9E-58 T 22-04-2016 MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 Gene3D G3DSA:3.40.50.150 17 210 5.2E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05125 3915040df0be8ff6b2b9dd2df69bb24f 213 PANTHER PTHR11579 1 208 4.2E-63 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 SMART SM00465 196 275 1.3E-11 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 Gene3D G3DSA:3.30.420.10 2 165 2.7E-49 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 SUPERFAMILY SSF53098 2 195 9.38E-53 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 SMART SM00479 1 166 1.0E-40 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 Gene3D G3DSA:3.40.1440.10 197 270 2.6E-8 T 22-04-2016 IPR027299 GIY-YIG domain MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 PANTHER PTHR30231:SF8 2 163 7.4E-39 T 22-04-2016 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 SUPERFAMILY SSF82771 197 274 9.02E-17 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 Pfam PF00929 Exonuclease 4 157 5.8E-28 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 193 1.0E-27 T 22-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 PANTHER PTHR30231 2 163 7.4E-39 T 22-04-2016 MED134_RS05150 f6d908ab777781269d39c702b3a000fa 459 Pfam PF01541 GIY-YIG catalytic domain 198 270 2.8E-10 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS14460 799516e795f82c8235afc940cd552484 406 PIRSF PIRSF000294 54 398 3.1E-53 T 22-04-2016 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 MED134_RS14460 799516e795f82c8235afc940cd552484 406 PANTHER PTHR30600 37 400 1.7E-82 T 22-04-2016 MED134_RS14460 799516e795f82c8235afc940cd552484 406 SUPERFAMILY SSF46626 64 220 9.69E-40 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS14460 799516e795f82c8235afc940cd552484 406 Gene3D G3DSA:1.10.760.10 75 216 3.3E-39 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS14460 799516e795f82c8235afc940cd552484 406 Gene3D G3DSA:1.10.760.10 217 392 1.1E-37 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS14460 799516e795f82c8235afc940cd552484 406 PANTHER PTHR30600:SF5 37 400 1.7E-82 T 22-04-2016 MED134_RS14460 799516e795f82c8235afc940cd552484 406 Pfam PF03150 Di-haem cytochrome c peroxidase 249 365 1.1E-6 T 22-04-2016 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MED134_RS14460 799516e795f82c8235afc940cd552484 406 Pfam PF03150 Di-haem cytochrome c peroxidase 85 228 5.8E-39 T 22-04-2016 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MED134_RS14460 799516e795f82c8235afc940cd552484 406 SUPERFAMILY SSF46626 221 391 1.51E-26 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS12985 bcd9ee64fc5199b20054fe893638b9e7 254 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 253 35.193 T 22-04-2016 IPR005583 Peroxide stress protein YaaA MED134_RS12985 bcd9ee64fc5199b20054fe893638b9e7 254 PANTHER PTHR30283:SF3 2 254 5.2E-102 T 22-04-2016 MED134_RS12985 bcd9ee64fc5199b20054fe893638b9e7 254 PANTHER PTHR30283 2 254 5.2E-102 T 22-04-2016 MED134_RS12985 bcd9ee64fc5199b20054fe893638b9e7 254 Pfam PF03883 Protein of unknown function (DUF328) 1 241 1.1E-90 T 22-04-2016 IPR005583 Peroxide stress protein YaaA MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 PIRSF PIRSF000477 1 270 1.0E-88 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 PANTHER PTHR11904:SF9 1 270 1.3E-98 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 Gene3D G3DSA:3.40.50.1580 3 269 5.8E-91 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 PANTHER PTHR11904 1 270 1.3E-98 T 22-04-2016 IPR001369 PNP/MTAP phosphorylase MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 SUPERFAMILY SSF53167 3 270 4.97E-85 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 Pfam PF01048 Phosphorylase superfamily 22 267 2.2E-47 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MED134_RS06580 dd376e242dd2a8185b6db60e341c16ed 270 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 21 268 5.6E-87 T 22-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Gene3D G3DSA:3.40.1390.10 7 100 4.5E-25 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Gene3D G3DSA:3.40.1190.10 101 329 3.7E-70 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Pfam PF08245 Mur ligase middle domain 110 306 3.1E-48 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 SUPERFAMILY SSF53244 326 485 5.23E-45 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 414 1.1E-19 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 PANTHER PTHR23135 11 487 5.2E-175 T 22-04-2016 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 482 4.6E-154 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 SUPERFAMILY SSF63418 12 99 5.89E-22 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Pfam PF01225 Mur ligase family, catalytic domain 24 98 2.5E-9 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 SUPERFAMILY SSF53623 101 323 5.63E-67 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 PANTHER PTHR23135:SF4 11 487 5.2E-175 T 22-04-2016 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 11 482 32.301 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 MED134_RS12510 9747e2ee9e15438d8d3151e851bfdf14 487 Gene3D G3DSA:3.90.190.20 330 474 2.9E-50 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 SUPERFAMILY SSF111384 24 168 1.44E-22 T 22-04-2016 IPR024930 Skp domain MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 Gene3D G3DSA:3.90.700.10 52 90 7.0E-4 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 PANTHER PTHR35089 6 144 4.4E-19 T 22-04-2016 MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 Pfam PF03938 Outer membrane protein (OmpH-like) 11 168 1.8E-34 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 SMART SM00935 11 169 8.3E-34 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 Gene3D G3DSA:3.30.910.20 94 168 2.3E-20 T 22-04-2016 MED134_RS07540 5ebcf94b138ad0e46b72567f43603730 170 Gene3D G3DSA:3.30.910.20 13 51 2.3E-20 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Pfam PF11799 impB/mucB/samB family C-terminal domain 241 355 1.7E-8 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Pfam PF00817 impB/mucB/samB family 5 150 8.3E-35 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Pfam PF13438 Domain of unknown function (DUF4113) 368 421 6.7E-16 T 22-04-2016 IPR025188 Domain of unknown function DUF4113 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Gene3D G3DSA:3.30.1490.100 244 355 1.3E-4 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 SUPERFAMILY SSF56672 1 236 1.07E-65 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Gene3D G3DSA:1.10.150.20 178 237 1.9E-10 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 PANTHER PTHR11076:SF40 1 396 1.7E-133 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 PANTHER PTHR11076 1 396 1.7E-133 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 Gene3D G3DSA:3.30.70.270 67 155 2.2E-23 T 22-04-2016 MED134_RS09050 16419124745d23b27e54d5f43cab32ff 424 SUPERFAMILY SSF100879 241 346 2.88E-5 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 SUPERFAMILY SSF50346 100 169 1.18E-14 T 22-04-2016 IPR011033 PRC-barrel-like MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 7 169 7.9E-30 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 Gene3D G3DSA:2.30.30.240 100 169 4.7E-14 T 22-04-2016 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 Pfam PF01782 RimM N-terminal domain 9 88 9.8E-11 T 22-04-2016 IPR002676 RimM protein GO:0006364 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 6 169 18.25 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 Gene3D G3DSA:2.40.30.60 2 94 1.2E-11 T 22-04-2016 IPR002676 RimM protein GO:0006364 MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 SUPERFAMILY SSF50447 5 94 3.53E-17 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS07590 16777f57177fbb5a1036549badcf80e6 174 PANTHER PTHR33692 1 172 1.1E-30 T 22-04-2016 MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 PANTHER PTHR34134:SF1 1 119 4.0E-34 T 22-04-2016 MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 PIRSF PIRSF019455 1 119 1.6E-29 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 SUPERFAMILY SSF46785 1 117 3.62E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 PANTHER PTHR34134 1 119 4.0E-34 T 22-04-2016 MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 Gene3D G3DSA:1.10.10.10 1 75 9.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10335 7fe0c90766e714a079e85aa6c2f0ffc2 119 Pfam PF03965 Penicillinase repressor 4 116 1.2E-32 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 Gene3D G3DSA:3.90.1530.10 36 136 2.4E-34 T 22-04-2016 MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 216 3.6E-50 T 22-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 Pfam PF02195 ParB-like nuclease domain 42 131 1.4E-22 T 22-04-2016 IPR003115 ParB/Sulfiredoxin MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 PANTHER PTHR33375 1 295 1.0E-91 T 22-04-2016 MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 SMART SM00470 41 131 1.4E-30 T 22-04-2016 IPR003115 ParB/Sulfiredoxin MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 SUPERFAMILY SSF109709 123 232 1.67E-34 T 22-04-2016 MED134_RS05375 46541cac20ff143c147fa187bb3dc8ea 299 SUPERFAMILY SSF110849 40 133 6.28E-27 T 22-04-2016 IPR003115 ParB/Sulfiredoxin MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 126 136 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 Gene3D G3DSA:3.20.20.140 1 253 1.1E-83 T 22-04-2016 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 PANTHER PTHR10060 5 257 1.2E-98 T 22-04-2016 IPR001130 TatD family GO:0016788 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 PIRSF PIRSF005902 1 258 2.7E-74 T 22-04-2016 IPR001130 TatD family GO:0016788 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 Pfam PF01026 TatD related DNase 4 253 2.2E-69 T 22-04-2016 IPR001130 TatD family GO:0016788 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 SUPERFAMILY SSF51556 3 254 1.31E-82 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 PANTHER PTHR10060:SF21 5 257 1.2E-98 T 22-04-2016 MED134_RS05970 deb9e111221123324b74ce7dd60042a2 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 253 6.6E-73 T 22-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 MED134_RS04275 b2f7f464eb7f2a1daa7b415e51368fd4 845 SMART SM00631 55 377 1.6E-4 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS04275 b2f7f464eb7f2a1daa7b415e51368fd4 845 SUPERFAMILY SSF52317 606 840 4.12E-14 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS04275 b2f7f464eb7f2a1daa7b415e51368fd4 845 Pfam PF00246 Zinc carboxypeptidase 61 227 9.2E-18 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS04275 b2f7f464eb7f2a1daa7b415e51368fd4 845 Gene3D G3DSA:3.40.630.10 53 317 1.4E-26 T 22-04-2016 MED134_RS04275 b2f7f464eb7f2a1daa7b415e51368fd4 845 SUPERFAMILY SSF53187 49 362 1.15E-50 T 22-04-2016 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Gene3D G3DSA:2.30.42.10 105 184 3.3E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 SUPERFAMILY SSF52096 196 356 9.28E-66 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 SUPERFAMILY SSF52096 41 119 9.28E-66 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 59 356 4.3E-80 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 SUPERFAMILY SSF50156 73 193 3.18E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Gene3D G3DSA:3.90.226.10 507 525 4.3E-59 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Gene3D G3DSA:3.90.226.10 403 415 4.3E-59 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Gene3D G3DSA:3.90.226.10 185 355 4.3E-59 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 SMART SM00245 163 357 5.0E-47 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 PANTHER PTHR32060 39 437 1.8E-100 T 22-04-2016 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Gene3D G3DSA:3.30.750.44 60 104 1.4E-4 T 22-04-2016 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Pfam PF13180 PDZ domain 102 177 1.9E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 PANTHER PTHR32060:SF9 39 437 1.8E-100 T 22-04-2016 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 SMART SM00228 99 174 3.1E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS08145 1e0578e5935021c6e212d2ef8b86db70 528 Pfam PF03572 Peptidase family S41 202 356 9.5E-46 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS05200 f548548dfb54b712b0b01118ae1c29cb 296 Pfam PF16119 Domain of unknown function (DUF4835) 20 294 3.2E-106 T 22-04-2016 IPR032274 Protein of unknown function DUF4835 MED134_RS09425 fad654832b5057c647efb76967757f39 287 SUPERFAMILY SSF52943 2 285 1.16E-80 T 22-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain MED134_RS09425 fad654832b5057c647efb76967757f39 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 285 31.984 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 22-04-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site MED134_RS09425 fad654832b5057c647efb76967757f39 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 285 9.4E-94 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 PANTHER PTHR11693 1 287 3.6E-112 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 Gene3D G3DSA:1.10.287.80 235 280 1.0E-26 T 22-04-2016 MED134_RS09425 fad654832b5057c647efb76967757f39 287 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 4.5E-33 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 PRINTS PR00126 ATP synthase gamma subunit signature 165 182 4.5E-33 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 4.5E-33 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 4.5E-33 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS09425 fad654832b5057c647efb76967757f39 287 Gene3D G3DSA:1.10.287.80 19 60 5.9E-30 T 22-04-2016 MED134_RS09425 fad654832b5057c647efb76967757f39 287 Gene3D G3DSA:1.10.287.80 200 234 5.9E-30 T 22-04-2016 MED134_RS09425 fad654832b5057c647efb76967757f39 287 Gene3D G3DSA:3.40.1380.10 67 190 7.4E-36 T 22-04-2016 MED134_RS09425 fad654832b5057c647efb76967757f39 287 Pfam PF00231 ATP synthase 3 285 7.4E-90 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 PANTHER PTHR11550 1 530 0.0 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 SUPERFAMILY SSF52540 4 269 1.52E-117 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 Hamap MF_01227 CTP synthase [pyrG]. 4 535 49.792 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 Pfam PF06418 CTP synthase N-terminus 5 269 2.0E-122 T 22-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 SUPERFAMILY SSF52317 292 535 7.98E-84 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 Pfam PF00117 Glutamine amidotransferase class-I 305 529 2.7E-56 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 TIGRFAM TIGR00337 PyrG: CTP synthase 4 530 7.7E-240 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 Gene3D G3DSA:3.40.50.300 3 287 2.6E-129 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14215 472aed9377abe2a5db7ca9eb3b4fe473 544 Gene3D G3DSA:3.40.50.880 291 536 1.3E-102 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS09080 db99c1b4729db5b836ab9837533daf5f 151 PANTHER PTHR23091:SF275 12 151 3.2E-35 T 22-04-2016 MED134_RS09080 db99c1b4729db5b836ab9837533daf5f 151 Pfam PF13673 Acetyltransferase (GNAT) domain 30 150 6.8E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS09080 db99c1b4729db5b836ab9837533daf5f 151 PANTHER PTHR23091 12 151 3.2E-35 T 22-04-2016 MED134_RS09080 db99c1b4729db5b836ab9837533daf5f 151 Gene3D G3DSA:3.40.630.30 8 150 3.6E-40 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09080 db99c1b4729db5b836ab9837533daf5f 151 SUPERFAMILY SSF55729 10 151 5.78E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 Pfam PF00512 His Kinase A (phospho-acceptor) domain 317 383 1.5E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 Gene3D G3DSA:1.10.287.130 308 370 1.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 Gene3D G3DSA:3.30.565.10 371 533 1.1E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 SMART SM00387 428 534 7.9E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 PANTHER PTHR24423 309 533 4.7E-42 T 22-04-2016 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 532 2.2E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 SMART SM00388 316 384 1.6E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 SUPERFAMILY SSF55874 374 533 1.83E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 SUPERFAMILY SSF47384 302 384 1.04E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 3.4E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 491 3.4E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS07145 cc773e83d3a3cbef3a9bad13e52c0300 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 3.4E-6 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 Pfam PF03572 Peptidase family S41 310 393 3.4E-6 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 Pfam PF03572 Peptidase family S41 254 301 1.2E-4 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 Gene3D G3DSA:3.90.226.10 239 304 8.6E-8 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 Gene3D G3DSA:3.90.226.10 310 410 1.9E-10 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 SUPERFAMILY SSF52096 245 399 1.08E-26 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS14645 d669f31cc11c4c902847258d1a398bdf 414 SUPERFAMILY SSF52096 48 122 1.08E-26 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS04380 48671422574a34fe11556addfefff7cd 241 PANTHER PTHR12532:SF0 1 238 5.6E-83 T 22-04-2016 MED134_RS04380 48671422574a34fe11556addfefff7cd 241 PANTHER PTHR12532 1 238 5.6E-83 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Gene3D G3DSA:3.30.70.980 134 200 6.7E-27 T 22-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 MED134_RS04380 48671422574a34fe11556addfefff7cd 241 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 2 234 1.9E-76 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 236 28.286 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Gene3D G3DSA:1.10.10.200 1 78 4.9E-29 T 22-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like MED134_RS04380 48671422574a34fe11556addfefff7cd 241 SUPERFAMILY SSF75625 1 237 1.31E-78 T 22-04-2016 IPR029072 YebC-like MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Gene3D G3DSA:3.30.1270.10 209 238 6.0E-33 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Gene3D G3DSA:3.30.1270.10 79 133 6.0E-33 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 MED134_RS04380 48671422574a34fe11556addfefff7cd 241 Pfam PF01709 Transcriptional regulator 5 233 8.0E-78 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 SUPERFAMILY SSF46785 2 116 7.8E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 PIRSF PIRSF019455 1 117 4.1E-26 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 Gene3D G3DSA:1.10.10.10 1 76 9.3E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 Pfam PF03965 Penicillinase repressor 4 115 4.1E-31 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 PANTHER PTHR34134 1 117 1.8E-34 T 22-04-2016 MED134_RS02125 9494f582e73ea6cc35e8545dcd306ee1 117 PANTHER PTHR34134:SF1 1 117 1.8E-34 T 22-04-2016 MED134_RS13575 8bf485fe633a5885cf3acc1bdc6d969f 338 Pfam PF01368 DHH family 18 169 1.7E-21 T 22-04-2016 IPR001667 DDH domain MED134_RS13575 8bf485fe633a5885cf3acc1bdc6d969f 338 Gene3D G3DSA:3.90.1640.10 17 208 8.3E-38 T 22-04-2016 MED134_RS13575 8bf485fe633a5885cf3acc1bdc6d969f 338 Pfam PF02272 DHHA1 domain 270 318 9.2E-7 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 MED134_RS13575 8bf485fe633a5885cf3acc1bdc6d969f 338 SUPERFAMILY SSF64182 17 320 3.27E-63 T 22-04-2016 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 5 151 1.8E-60 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 4.3E-44 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 4.3E-44 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.3E-44 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.3E-44 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 4.3E-44 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 5 325 7.7E-132 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 SUPERFAMILY SSF51735 5 167 5.65E-70 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 Gene3D G3DSA:3.40.50.720 2 159 2.3E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 SUPERFAMILY SSF55347 150 313 6.25E-69 T 22-04-2016 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PIRSF PIRSF000149 2 333 1.8E-127 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 PANTHER PTHR10836 1 328 1.1E-211 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 2.2E-62 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 SMART SM00846 4 151 9.9E-94 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 MED134_RS01055 f47093810e535faac5cd17c0d648f7ce 333 Gene3D G3DSA:3.30.360.10 160 315 1.9E-74 T 22-04-2016 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.9E-57 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-35 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-35 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-35 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-35 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.894 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.0E-47 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 PANTHER PTHR12220 1 132 2.9E-68 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 SUPERFAMILY SSF54686 1 136 3.79E-56 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MED134_RS12270 d3a0693a61ff2a8f6cb64ac4aeb3c866 140 Gene3D G3DSA:3.90.1170.10 23 136 1.3E-51 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 Gene3D G3DSA:2.30.40.10 29 86 2.2E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 Gene3D G3DSA:2.30.40.10 383 393 2.2E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 SUPERFAMILY SSF51556 242 374 1.41E-12 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS03035 823704d386757ac276f5a954371f36a2 429 Pfam PF01979 Amidohydrolase family 312 392 1.6E-9 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 SUPERFAMILY SSF51338 373 394 1.56E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 SUPERFAMILY SSF51338 25 85 1.56E-12 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS03035 823704d386757ac276f5a954371f36a2 429 Gene3D G3DSA:2.30.40.10 313 382 1.5E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 PANTHER PTHR11907 5 211 1.6E-29 T 22-04-2016 MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 PANTHER PTHR11907:SF9 5 211 1.6E-29 T 22-04-2016 MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 SUPERFAMILY SSF53271 67 223 4.7E-23 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 Pfam PF00156 Phosphoribosyl transferase domain 134 216 2.0E-6 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 ProSitePatterns PS00213 Lipocalin signature. 88 99 - T 22-04-2016 IPR022272 Lipocalin family conserved site MED134_RS08065 920e6eab7ddf751f92cf19b49ddbaa4d 226 Gene3D G3DSA:3.40.50.2020 27 209 4.4E-22 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SMART SM00257 173 216 3.0E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SMART SM00257 102 146 3.1E-10 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SMART SM00257 40 83 0.055 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SMART SM00257 233 276 0.02 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SUPERFAMILY SSF54106 101 146 6.41E-8 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SUPERFAMILY SSF54106 172 216 2.88E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SUPERFAMILY SSF53822 354 624 5.38E-12 T 22-04-2016 IPR028082 Periplasmic binding protein-like I MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Gene3D G3DSA:3.10.350.10 233 277 7.8E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Gene3D G3DSA:3.10.350.10 172 217 2.2E-11 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SUPERFAMILY SSF54106 39 83 1.44E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Gene3D G3DSA:3.40.50.2300 370 482 2.3E-6 T 22-04-2016 MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Pfam PF01476 LysM domain 234 276 0.0015 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Pfam PF01476 LysM domain 103 146 7.6E-8 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Pfam PF01476 LysM domain 41 69 1.9E-7 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Pfam PF01476 LysM domain 174 216 2.4E-4 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Gene3D G3DSA:3.10.350.10 100 147 3.2E-12 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 Gene3D G3DSA:3.10.350.10 37 84 7.5E-10 T 22-04-2016 IPR018392 LysM domain MED134_RS03405 dd741a9ee0354d64f8979358c795fb97 686 SUPERFAMILY SSF54106 232 276 3.53E-5 T 22-04-2016 IPR018392 LysM domain MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 PANTHER PTHR39323 1 190 1.8E-23 T 22-04-2016 MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 Gene3D G3DSA:3.60.21.10 8 109 8.6E-10 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 1 189 3.0E-64 T 22-04-2016 IPR026336 Metallophosphoesterase, DNA ligase-associated MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 Pfam PF00149 Calcineurin-like phosphoesterase 8 99 2.8E-6 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 SUPERFAMILY SSF56300 9 140 2.69E-16 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 PANTHER PTHR39323:SF1 1 190 1.8E-23 T 22-04-2016 MED134_RS08570 aa9385cbb8aea4de5f612f360a9e85e7 192 PIRSF PIRSF000887 1 189 6.3E-36 T 22-04-2016 IPR024173 Phosphoesterase, MJ0037 MED134_RS03295 8351b6fc2c32ab9c968c5539121eee99 131 Gene3D G3DSA:1.10.3680.10 5 49 8.1E-8 T 22-04-2016 IPR029024 TerB-like MED134_RS03295 8351b6fc2c32ab9c968c5539121eee99 131 Pfam PF05099 Tellurite resistance protein TerB 5 46 4.0E-6 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal MED134_RS03295 8351b6fc2c32ab9c968c5539121eee99 131 SUPERFAMILY SSF158682 5 111 2.88E-16 T 22-04-2016 IPR029024 TerB-like MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 SUPERFAMILY SSF52540 332 551 2.41E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 Pfam PF00664 ABC transporter transmembrane region 25 289 5.0E-8 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 PANTHER PTHR24221 1 497 2.6E-55 T 22-04-2016 MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 Gene3D G3DSA:1.20.1560.10 8 319 6.8E-29 T 22-04-2016 MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 Gene3D G3DSA:3.40.50.300 333 553 5.0E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 Pfam PF00005 ABC transporter 353 499 3.1E-16 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 SUPERFAMILY SSF90123 7 322 7.46E-37 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS06335 b76905dd0c789a189760567f59f801f7 555 PANTHER PTHR24221:SF138 1 497 2.6E-55 T 22-04-2016 MED134_RS02950 aec09ef5801783d6246d7971949e98e2 251 SUPERFAMILY SSF52317 49 240 9.16E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02950 aec09ef5801783d6246d7971949e98e2 251 Pfam PF01965 DJ-1/PfpI family 50 217 8.2E-17 T 22-04-2016 IPR002818 DJ-1/PfpI MED134_RS02950 aec09ef5801783d6246d7971949e98e2 251 Gene3D G3DSA:3.40.50.880 49 241 9.7E-42 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02950 aec09ef5801783d6246d7971949e98e2 251 PANTHER PTHR11019 4 238 3.0E-12 T 22-04-2016 MED134_RS02950 aec09ef5801783d6246d7971949e98e2 251 PANTHER PTHR11019:SF58 4 238 3.0E-12 T 22-04-2016 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 SUPERFAMILY SSF46946 2 114 3.39E-42 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 Gene3D G3DSA:4.10.910.10 72 123 2.1E-27 T 22-04-2016 IPR027437 30s ribosomal protein S13, C-terminal MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 PANTHER PTHR10871 1 122 4.6E-68 T 22-04-2016 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 PIRSF PIRSF002134 1 124 1.6E-38 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 Gene3D G3DSA:1.10.8.50 1 70 8.3E-27 T 22-04-2016 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 Pfam PF00416 Ribosomal protein S13/S18 3 108 6.0E-31 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 22-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.888 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12345 3d5d7f597619eec7f70a6da110396eae 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.2E-50 T 22-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 PANTHER PTHR11935 3 297 3.9E-86 T 22-04-2016 MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Pfam PF00581 Rhodanese-like domain 261 353 1.6E-11 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Pfam PF00581 Rhodanese-like domain 365 456 3.7E-8 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Gene3D G3DSA:3.60.15.10 4 239 3.3E-51 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SUPERFAMILY SSF52821 359 465 1.28E-21 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SUPERFAMILY SSF52821 224 358 6.29E-20 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SMART SM00450 259 357 1.2E-5 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SMART SM00450 364 459 1.1E-10 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SUPERFAMILY SSF56281 1 242 2.52E-47 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Pfam PF00753 Metallo-beta-lactamase superfamily 15 156 3.4E-13 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Gene3D G3DSA:3.40.250.10 240 357 4.5E-21 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 Gene3D G3DSA:3.40.250.10 360 466 3.0E-22 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 SMART SM00849 12 182 2.8E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS12605 ec1be97129be489e758a8a7f36064766 469 PANTHER PTHR11935:SF9 3 297 3.9E-86 T 22-04-2016 MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 SUPERFAMILY SSF50939 376 517 1.24E-58 T 22-04-2016 IPR011040 Sialidases MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 SUPERFAMILY SSF50939 47 154 1.24E-58 T 22-04-2016 IPR011040 Sialidases MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 SUPERFAMILY SSF50939 184 288 1.24E-58 T 22-04-2016 IPR011040 Sialidases MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 SUPERFAMILY SSF50939 547 818 8.14E-34 T 22-04-2016 IPR011040 Sialidases MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 Pfam PF02012 BNR/Asp-box repeat 381 392 0.1 T 22-04-2016 IPR002860 BNR repeat MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 Gene3D G3DSA:2.130.10.140 373 517 2.3E-78 T 22-04-2016 MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 Gene3D G3DSA:2.130.10.140 61 291 2.3E-78 T 22-04-2016 MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 Gene3D G3DSA:2.130.10.140 582 749 2.6E-31 T 22-04-2016 MED134_RS10985 baaa203b0ec7c374f57685d032180098 957 Gene3D G3DSA:2.130.10.140 750 864 2.8E-10 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Gene3D G3DSA:2.170.130.10 114 221 5.9E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Pfam PF13715 CarboxypepD_reg-like domain 25 109 4.8E-18 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 PANTHER PTHR30069 22 354 6.1E-39 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 SUPERFAMILY SSF49464 23 107 1.57E-15 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 PANTHER PTHR30069:SF1 22 354 6.1E-39 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Gene3D G3DSA:2.60.40.1120 24 97 7.8E-16 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Gene3D G3DSA:2.40.170.20 248 451 1.8E-38 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Gene3D G3DSA:2.40.170.20 486 777 1.8E-38 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 SUPERFAMILY SSF56935 499 792 1.68E-72 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 SUPERFAMILY SSF56935 105 455 1.68E-72 T 22-04-2016 MED134_RS13920 250c754627d3149ad6dd392457b4fdcb 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 121 219 6.2E-11 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 Gene3D G3DSA:1.10.275.10 1 117 5.1E-45 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 ProSitePatterns PS00163 Fumarate lyases signature. 293 302 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 446 5.2E-119 T 22-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PRINTS PR00149 Fumarate lyase superfamily signature 115 133 1.7E-16 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PRINTS PR00149 Fumarate lyase superfamily signature 161 179 1.7E-16 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PRINTS PR00149 Fumarate lyase superfamily signature 250 277 1.7E-16 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PRINTS PR00149 Fumarate lyase superfamily signature 293 309 1.7E-16 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PANTHER PTHR11444 4 447 2.0E-193 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 Gene3D G3DSA:1.10.40.30 389 445 6.4E-28 T 22-04-2016 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 SUPERFAMILY SSF48557 4 446 2.67E-90 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 PANTHER PTHR11444:SF17 4 447 2.0E-193 T 22-04-2016 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 Pfam PF08328 Adenylosuccinate lyase C-terminal 330 445 1.0E-49 T 22-04-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 Gene3D G3DSA:1.20.200.10 118 388 3.6E-76 T 22-04-2016 MED134_RS02805 5db34f33bfb11268d7a2baa919f9946e 447 Pfam PF00206 Lyase 14 311 6.4E-49 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 SUPERFAMILY SSF56925 55 179 4.45E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 Gene3D G3DSA:3.30.1330.60 328 430 6.3E-24 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 PRINTS PR01021 OMPA domain signature 376 392 1.2E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 PRINTS PR01021 OMPA domain signature 361 376 1.2E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 PRINTS PR01021 OMPA domain signature 331 353 1.2E-7 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 SUPERFAMILY SSF103088 324 429 1.06E-22 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 PANTHER PTHR30128 328 430 2.5E-22 T 22-04-2016 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 Gene3D G3DSA:2.40.160.20 60 185 1.4E-4 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 Pfam PF13505 Outer membrane protein beta-barrel domain 9 177 1.8E-9 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel MED134_RS02860 2308e4b714ee3c28bf1c8659734ade56 431 Pfam PF00691 OmpA family 330 421 8.1E-12 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Gene3D G3DSA:4.10.320.10 123 175 1.7E-14 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 204 434 4.8E-71 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 SUPERFAMILY SSF47005 124 169 2.22E-8 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Gene3D G3DSA:2.40.50.100 3 91 7.9E-24 T 22-04-2016 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Pfam PF02817 e3 binding domain 128 163 1.3E-11 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 SUPERFAMILY SSF51230 3 88 2.78E-23 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Pfam PF00364 Biotin-requiring enzyme 5 77 2.5E-16 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 SUPERFAMILY SSF52777 204 433 3.51E-77 T 22-04-2016 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 PANTHER PTHR23151 187 432 3.2E-134 T 22-04-2016 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 PANTHER PTHR23151 5 171 3.2E-134 T 22-04-2016 MED134_RS05110 dfaaa9dba947f4c1303ba64698bedd76 439 Gene3D G3DSA:3.30.559.10 195 433 1.6E-75 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 Pfam PF13432 Tetratricopeptide repeat 180 241 1.1E-4 T 22-04-2016 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 SUPERFAMILY SSF48452 139 242 2.62E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 Pfam PF13174 Tetratricopeptide repeat 143 165 0.13 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 SMART SM00028 211 244 86.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 SMART SM00028 174 207 0.019 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 Gene3D G3DSA:1.25.40.10 142 193 5.5E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05430 686ca33b0f8c5f2d097582e0d8614a91 261 Gene3D G3DSA:1.25.40.10 194 240 2.1E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 91 188 9.9E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SUPERFAMILY SSF48452 96 272 9.21E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SUPERFAMILY SSF48452 539 624 9.66E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SUPERFAMILY SSF48452 310 346 9.66E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 191 261 7.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 305 322 7.0E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SUPERFAMILY SSF48452 303 376 4.3E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SMART SM00028 119 152 85.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SMART SM00028 232 265 55.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SMART SM00028 195 228 0.34 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 SMART SM00028 309 342 1.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 547 622 1.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 323 377 1.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Gene3D G3DSA:1.25.40.10 699 725 1.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Pfam PF13181 Tetratricopeptide repeat 195 227 0.011 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09380 56fb124478cef654e6df990b972797dd 845 Pfam PF13181 Tetratricopeptide repeat 310 337 0.018 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS03195 23206b8688a960edca897f14d8465ffd 179 Pfam PF02635 DsrE/DsrF-like family 55 179 1.0E-12 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein MED134_RS03195 23206b8688a960edca897f14d8465ffd 179 SUPERFAMILY SSF75169 53 179 5.0E-16 T 22-04-2016 IPR027396 DsrEFH-like MED134_RS03195 23206b8688a960edca897f14d8465ffd 179 Gene3D G3DSA:3.40.1260.10 79 177 4.4E-6 T 22-04-2016 IPR027396 DsrEFH-like MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 PANTHER PTHR10245:SF26 1 60 3.9E-20 T 22-04-2016 MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 SMART SM00530 4 59 1.8E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 Pfam PF01381 Helix-turn-helix 9 58 1.3E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 Gene3D G3DSA:1.10.260.40 2 64 1.7E-20 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 SUPERFAMILY SSF47413 2 62 3.22E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS00120 31d5c72d32ec1af3151ebf74f8032de8 66 PANTHER PTHR10245 1 60 3.9E-20 T 22-04-2016 MED134_RS07965 38143d4c6c49ba63931a3ba397617ae4 92 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 6 50 4.0E-7 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS07965 38143d4c6c49ba63931a3ba397617ae4 92 Gene3D G3DSA:2.60.15.10 1 92 3.6E-23 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS07965 38143d4c6c49ba63931a3ba397617ae4 92 SUPERFAMILY SSF51344 1 92 1.96E-14 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS07965 38143d4c6c49ba63931a3ba397617ae4 92 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 1 92 1.1E-16 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 MED134_RS07220 9a03197676d68708dfa90dbf205fabc7 466 Pfam PF07670 Nucleoside recognition 131 230 2.4E-10 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS07220 9a03197676d68708dfa90dbf205fabc7 466 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 242 464 9.6E-71 T 22-04-2016 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS07220 9a03197676d68708dfa90dbf205fabc7 466 PANTHER PTHR10590 42 465 1.6E-168 T 22-04-2016 IPR008276 Concentrative nucleoside transporter GO:0005337|GO:0016020|GO:1901642 Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS07220 9a03197676d68708dfa90dbf205fabc7 466 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 45 118 1.0E-23 T 22-04-2016 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 Pfam PF08323 Starch synthase catalytic domain 2 231 3.8E-59 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 SUPERFAMILY SSF53756 3 468 1.29E-99 T 22-04-2016 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 Gene3D G3DSA:3.40.50.2000 245 447 3.3E-61 T 22-04-2016 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 Pfam PF00534 Glycosyl transferases group 1 279 417 1.5E-11 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 Hamap MF_00484 Glycogen synthase [glgA]. 1 466 36.696 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 PANTHER PTHR12526:SF17 1 466 6.0E-112 T 22-04-2016 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 466 4.1E-142 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS04475 8e0ac8707ab6a1e6bab7d82630da12bd 481 PANTHER PTHR12526 1 466 6.0E-112 T 22-04-2016 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 PANTHER PTHR11986 5 426 2.5E-251 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 SUPERFAMILY SSF53383 8 423 1.51E-117 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 PANTHER PTHR11986:SF18 5 426 2.5E-251 T 22-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 9 422 4.1E-193 T 22-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 Pfam PF00202 Aminotransferase class-III 20 421 1.7E-115 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 Gene3D G3DSA:3.90.1150.10 8 63 2.9E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 Gene3D G3DSA:3.90.1150.10 327 423 2.9E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS13875 38f9bee8df55e4b8e4989a725d81e594 426 Gene3D G3DSA:3.40.640.10 64 325 1.7E-80 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 SUPERFAMILY SSF52402 2 134 1.34E-17 T 22-04-2016 MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 Pfam PF00582 Universal stress protein family 1 134 2.5E-10 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 Gene3D G3DSA:3.40.50.620 1 135 1.3E-14 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 PRINTS PR01438 Universal stress protein signature 112 134 2.1E-8 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 PRINTS PR01438 Universal stress protein signature 94 106 2.1E-8 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04645 dd328b1201c2759e5eb942b9fc15b6b4 268 PRINTS PR01438 Universal stress protein signature 1 18 2.1E-8 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 452 462 - T 22-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 22 462 2.5E-107 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 401 432 - T 22-04-2016 IPR030390 RNA methyltransferase TrmA, active site MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 Pfam PF01938 TRAM domain 14 62 4.8E-5 T 22-04-2016 IPR002792 TRAM domain MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 Gene3D G3DSA:2.40.50.140 13 83 2.1E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 291 470 5.3E-20 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 Gene3D G3DSA:3.40.50.150 267 468 4.5E-63 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 SUPERFAMILY SSF50249 13 62 8.57E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 SUPERFAMILY SSF53335 72 469 2.16E-75 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 PANTHER PTHR11061:SF30 9 471 2.8E-154 T 22-04-2016 MED134_RS13865 1b87a43b339c37326780ec37a1a8b53c 471 PANTHER PTHR11061 9 471 2.8E-154 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 PANTHER PTHR11014 8 356 3.2E-50 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 SUPERFAMILY SSF53187 5 171 7.65E-45 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 SUPERFAMILY SSF53187 281 354 7.65E-45 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 Pfam PF01546 Peptidase family M20/M25/M40 67 351 2.2E-22 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 Gene3D G3DSA:3.40.630.10 6 180 4.4E-48 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 Gene3D G3DSA:3.40.630.10 294 355 4.4E-48 T 22-04-2016 MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 SUPERFAMILY SSF55031 172 264 8.52E-17 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 Gene3D G3DSA:3.30.70.360 181 262 4.7E-22 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS11770 da2cd10534375b0eaa7421f6c7e832f8 356 Pfam PF07687 Peptidase dimerisation domain 168 263 3.9E-13 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.0E-23 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 Pfam PF01250 Ribosomal protein S6 3 91 2.1E-28 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 PANTHER PTHR21011 1 91 3.7E-24 T 22-04-2016 MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 19.74 T 22-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 SUPERFAMILY SSF54995 1 98 1.96E-32 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS02220 40666a2183055bd224a011f3f95501b8 113 Gene3D G3DSA:3.30.70.60 1 97 8.6E-34 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 Pfam PF14579 Helix-hairpin-helix motif 741 824 9.5E-17 T 22-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 Gene3D G3DSA:3.20.20.140 716 756 1.6E-8 T 22-04-2016 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 Gene3D G3DSA:3.20.20.140 5 83 1.6E-8 T 22-04-2016 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 SMART SM00481 1 68 1.8E-5 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 253 665 9.9E-101 T 22-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 SUPERFAMILY SSF89550 5 68 7.06E-8 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 Pfam PF02811 PHP domain 3 106 2.1E-11 T 22-04-2016 IPR004013 PHP domain GO:0003824 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 152 935 7.8E-132 T 22-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS06275 97a18266076445fd7bb7e200183dfc29 1008 PANTHER PTHR32294 1 949 5.8E-161 T 22-04-2016 MED134_RS13075 586320e4911082b3b8ebde1f1a3b6a8d 207 PANTHER PTHR10681 24 206 2.2E-26 T 22-04-2016 MED134_RS13075 586320e4911082b3b8ebde1f1a3b6a8d 207 SUPERFAMILY SSF52833 31 206 8.69E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS13075 586320e4911082b3b8ebde1f1a3b6a8d 207 Gene3D G3DSA:3.40.30.10 34 197 4.2E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS13075 586320e4911082b3b8ebde1f1a3b6a8d 207 Pfam PF00578 AhpC/TSA family 34 153 8.3E-17 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS13075 586320e4911082b3b8ebde1f1a3b6a8d 207 PANTHER PTHR10681:SF91 24 206 2.2E-26 T 22-04-2016 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 SUPERFAMILY SSF82689 180 279 1.57E-25 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 SUPERFAMILY SSF82861 26 110 3.4E-19 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 Gene3D G3DSA:3.30.70.100 180 266 1.0E-21 T 22-04-2016 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 PANTHER PTHR30221:SF7 30 281 5.5E-86 T 22-04-2016 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 Gene3D G3DSA:2.30.30.60 127 176 5.7E-19 T 22-04-2016 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 Pfam PF00924 Mechanosensitive ion channel 70 268 5.1E-49 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 Pfam PF05552 Conserved TM helix 19 62 4.5E-8 T 22-04-2016 IPR008910 Conserved TM helix MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 SUPERFAMILY SSF50182 112 177 2.81E-17 T 22-04-2016 IPR010920 LSM domain MED134_RS11415 c628f1f055c65e87e90232f5944c5c80 281 PANTHER PTHR30221 30 281 5.5E-86 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 SUPERFAMILY SSF52540 344 622 9.43E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 710 718 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 SMART SM00464 43 237 1.9E-43 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Hamap MF_01973 Lon protease [lon]. 44 806 67.08 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Gene3D G3DSA:3.40.50.300 341 535 6.4E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PIRSF PIRSF001174 30 809 4.0E-295 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PANTHER PTHR10046 13 810 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 737 756 7.8E-52 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 629 645 7.8E-52 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 7.8E-52 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 390 409 7.8E-52 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 760 778 7.8E-52 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 603 806 5.3E-84 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Gene3D G3DSA:3.30.230.10 625 805 1.7E-68 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 44 236 8.0E-37 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 SUPERFAMILY SSF88697 43 235 1.37E-42 T 22-04-2016 IPR015947 PUA-like domain MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 386 523 9.8E-24 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 Gene3D G3DSA:1.10.8.60 536 617 4.3E-28 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 TIGRFAM TIGR00763 lon: endopeptidase La 46 805 6.7E-281 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 SUPERFAMILY SSF54211 630 805 2.05E-51 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 PANTHER PTHR10046:SF24 13 810 0.0 T 22-04-2016 MED134_RS04410 4fed45161ce7f23a65e9c3ec95a10241 816 SMART SM00382 382 527 2.5E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13155 c31f218172f1d3c548f1cfc4b8f0565b 417 PANTHER PTHR32507 70 403 2.0E-53 T 22-04-2016 MED134_RS13155 c31f218172f1d3c548f1cfc4b8f0565b 417 Pfam PF00999 Sodium/hydrogen exchanger family 20 404 5.6E-32 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MED134_RS13155 c31f218172f1d3c548f1cfc4b8f0565b 417 PANTHER PTHR32507:SF12 70 403 2.0E-53 T 22-04-2016 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Gene3D G3DSA:2.60.40.1120 436 505 1.1E-6 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Gene3D G3DSA:3.30.1330.60 532 646 2.8E-32 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Pfam PF00691 OmpA family 539 629 6.4E-15 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 PANTHER PTHR30128 525 646 1.6E-30 T 22-04-2016 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Pfam PF07676 WD40-like Beta Propeller Repeat 288 313 7.4E-6 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 SUPERFAMILY SSF48452 23 129 1.2E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Gene3D G3DSA:1.25.40.10 23 136 1.7E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 SUPERFAMILY SSF103088 527 645 2.35E-28 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 PRINTS PR01021 OMPA domain signature 570 585 2.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 PRINTS PR01021 OMPA domain signature 540 562 2.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 PRINTS PR01021 OMPA domain signature 585 601 2.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 Gene3D G3DSA:2.130.10.10 165 376 5.8E-11 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 SUPERFAMILY SSF82171 166 388 2.88E-13 T 22-04-2016 MED134_RS00020 cdc2b51f734ec43a801a6fa796892fe5 649 SUPERFAMILY SSF49478 436 503 1.77E-6 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 Pfam PF01494 FAD binding domain 7 362 8.2E-23 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 4.55E-17 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 4.55E-17 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 4.55E-17 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.55E-17 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 SUPERFAMILY SSF51905 6 178 5.7E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 SUPERFAMILY SSF51905 285 374 5.7E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 Gene3D G3DSA:3.50.50.60 286 367 7.2E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 Gene3D G3DSA:3.50.50.60 7 183 7.2E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PANTHER PTHR13789:SF205 3 440 4.8E-157 T 22-04-2016 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 Hamap MF_01971 Kynurenine 3-monooxygenase [kmo]. 4 450 26.987 T 22-04-2016 IPR027545 Kynurenine 3-monooxygenase GO:0004502|GO:0006569|GO:0019805 KEGG: 00380+1.14.13.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|UniPathway: UPA00253 MED134_RS12735 4408917950e3e0a7b73f8b50c2b73e3a 466 PANTHER PTHR13789 3 440 4.8E-157 T 22-04-2016 MED134_RS10250 ce2a298eda0e21efde449dc325385942 163 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 61 155 5.3E-9 T 22-04-2016 IPR000014 PAS domain MED134_RS10250 ce2a298eda0e21efde449dc325385942 163 Gene3D G3DSA:3.30.450.20 62 155 4.6E-21 T 22-04-2016 MED134_RS10250 ce2a298eda0e21efde449dc325385942 163 SUPERFAMILY SSF55785 62 155 1.13E-18 T 22-04-2016 IPR000014 PAS domain MED134_RS10250 ce2a298eda0e21efde449dc325385942 163 Pfam PF13426 PAS domain 62 154 6.1E-14 T 22-04-2016 IPR000014 PAS domain MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 SUPERFAMILY SSF51735 1 179 1.11E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 149 4.1E-12 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 PIRSF PIRSF036497 1 362 2.9E-62 T 22-04-2016 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 SUPERFAMILY SSF55347 157 342 3.2E-37 T 22-04-2016 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 Pfam PF00742 Homoserine dehydrogenase 157 355 4.6E-44 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 Gene3D G3DSA:3.30.360.10 179 337 2.3E-45 T 22-04-2016 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 Gene3D G3DSA:3.40.50.720 1 178 2.5E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 PANTHER PTHR21499:SF29 6 362 7.6E-69 T 22-04-2016 MED134_RS07095 4130b12ec91be69834f65160f9aef7ad 362 PANTHER PTHR21499 6 362 7.6E-69 T 22-04-2016 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 SMART SM00382 370 556 1.2E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 SUPERFAMILY SSF90123 17 328 1.24E-70 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 Pfam PF00664 ABC transporter transmembrane region 28 298 2.2E-41 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 PANTHER PTHR24221 19 581 1.4E-204 T 22-04-2016 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 Pfam PF00005 ABC transporter 362 510 1.0E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 Gene3D G3DSA:3.40.50.300 345 575 6.7E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 SUPERFAMILY SSF52540 336 580 2.05E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01850 a97a181616a8d36ab50d9669094daca9 583 Gene3D G3DSA:1.20.1560.10 18 329 3.7E-67 T 22-04-2016 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 Pfam PF01632 Ribosomal protein L35 2 62 7.7E-26 T 22-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.1E-27 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 22-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.192 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 SUPERFAMILY SSF143034 2 62 2.09E-22 T 22-04-2016 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 PANTHER PTHR33343 1 63 7.2E-25 T 22-04-2016 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.8E-18 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.8E-18 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MED134_RS06315 0bcc44dfa3cad8cf9aea35bbc14a3834 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.8E-18 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Pfam PF02772 S-adenosylmethionine synthetase, central domain 113 242 1.4E-40 T 22-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 115 125 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Gene3D G3DSA:3.30.300.10 255 416 1.4E-63 T 22-04-2016 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 PANTHER PTHR11964:SF1 400 410 3.1E-206 T 22-04-2016 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 PANTHER PTHR11964:SF1 3 379 3.1E-206 T 22-04-2016 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 99 4.2E-41 T 22-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 PIRSF PIRSF000497 1 416 1.0E-160 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 379 1.2E-150 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 244 378 2.6E-61 T 22-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 SUPERFAMILY SSF55973 244 416 1.14E-57 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 PANTHER PTHR11964 400 410 3.1E-206 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 PANTHER PTHR11964 3 379 3.1E-206 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Gene3D G3DSA:3.30.300.10 132 244 2.7E-32 T 22-04-2016 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 SUPERFAMILY SSF55973 111 243 2.04E-38 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 SUPERFAMILY SSF55973 2 108 3.14E-43 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 270 278 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 415 49.779 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 MED134_RS07110 d278d8977689a8270704043cdddf2f12 417 Gene3D G3DSA:3.30.300.10 10 131 3.6E-45 T 22-04-2016 MED134_RS13445 4bea1195de047497c7392641e94bc710 343 Pfam PF03016 Exostosin family 222 284 1.1E-8 T 22-04-2016 IPR004263 Exostosin-like MED134_RS14830 a292f46d09a111abf54bc081dc0b4b0d 351 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 279 351 4.5E-13 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS02410 7b244219ab7c8817790dee92e1f1046e 119 Pfam PF07883 Cupin domain 38 105 9.8E-10 T 22-04-2016 IPR013096 Cupin 2, conserved barrel MED134_RS02410 7b244219ab7c8817790dee92e1f1046e 119 Gene3D G3DSA:2.60.120.10 4 113 1.6E-22 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS02410 7b244219ab7c8817790dee92e1f1046e 119 SUPERFAMILY SSF51182 9 110 3.77E-20 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 PANTHER PTHR11019:SF126 173 262 4.9E-15 T 22-04-2016 MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 Gene3D G3DSA:1.10.10.60 171 207 1.7E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 Pfam PF12833 Helix-turn-helix domain 178 255 8.1E-16 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 PANTHER PTHR11019 173 262 4.9E-15 T 22-04-2016 MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 SMART SM00342 170 254 5.6E-7 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS11630 2c3ccbddd63177172c9087124808fdf0 267 Gene3D G3DSA:1.10.10.60 229 258 4.1E-4 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.8E-63 T 22-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 SUPERFAMILY SSF51735 1 184 1.29E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 PANTHER PTHR23309 2 393 1.2E-154 T 22-04-2016 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 282 5.9E-30 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 309 390 1.4E-14 T 22-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 SUPERFAMILY SSF48179 184 284 1.7E-29 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 182 207 - T 22-04-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Gene3D G3DSA:3.40.50.720 2 186 2.4E-62 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Gene3D G3DSA:1.10.1040.10 187 283 1.6E-30 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 Gene3D G3DSA:1.10.1040.10 308 393 4.5E-20 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MED134_RS11515 b4a843b508ab06a3ae05d36d038ceb3d 394 SUPERFAMILY SSF48179 307 393 8.5E-18 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 327 346 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 SUPERFAMILY SSF48173 214 434 1.83E-92 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 Gene3D G3DSA:3.40.50.620 2 147 1.8E-47 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 Gene3D G3DSA:1.10.579.10 267 434 7.0E-70 T 22-04-2016 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 Gene3D G3DSA:1.25.40.80 148 266 3.9E-28 T 22-04-2016 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PRINTS PR00147 DNA photolyase signature 144 160 9.3E-27 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PRINTS PR00147 DNA photolyase signature 307 323 9.3E-27 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PRINTS PR00147 DNA photolyase signature 327 345 9.3E-27 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PRINTS PR00147 DNA photolyase signature 366 380 9.3E-27 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PANTHER PTHR11455:SF18 1 434 1.4E-162 T 22-04-2016 MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 Pfam PF03441 FAD binding domain of DNA photolyase 258 432 1.4E-74 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 SUPERFAMILY SSF52425 4 176 9.03E-52 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 Pfam PF00875 DNA photolyase 8 165 2.7E-42 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS14060 14087bfb6cb6a16ae9e5d2f19c2b4cd3 436 PANTHER PTHR11455 1 434 1.4E-162 T 22-04-2016 MED134_RS12725 8274ecbfd595065840d9c61c2726ef47 105 SMART SM00465 3 81 5.2E-5 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS12725 8274ecbfd595065840d9c61c2726ef47 105 Pfam PF01541 GIY-YIG catalytic domain 4 76 4.9E-15 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS12725 8274ecbfd595065840d9c61c2726ef47 105 SUPERFAMILY SSF82771 3 75 1.44E-14 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS12725 8274ecbfd595065840d9c61c2726ef47 105 PANTHER PTHR34477 1 104 3.8E-26 T 22-04-2016 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Gene3D G3DSA:2.40.170.20 319 939 3.7E-41 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Gene3D G3DSA:2.40.170.20 230 255 3.7E-41 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Pfam PF14905 Outer membrane protein beta-barrel family 574 936 2.1E-24 T 22-04-2016 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 PANTHER PTHR30069 1 275 7.3E-33 T 22-04-2016 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 SUPERFAMILY SSF49464 22 107 9.42E-16 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Gene3D G3DSA:2.170.130.10 134 229 3.7E-14 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Pfam PF07715 TonB-dependent Receptor Plug Domain 135 226 1.5E-11 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 SUPERFAMILY SSF56935 314 939 1.47E-71 T 22-04-2016 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 SUPERFAMILY SSF56935 105 249 1.47E-71 T 22-04-2016 MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Gene3D G3DSA:2.60.40.1120 23 100 6.1E-16 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS11025 d62628e7cfa497ae493fe3589d3ea4a5 939 Pfam PF13715 CarboxypepD_reg-like domain 24 109 9.3E-19 T 22-04-2016 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 2 157 2.2E-60 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 158 32.677 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 ProSitePatterns PS00052 Ribosomal protein S7 signature. 19 45 - T 22-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 PANTHER PTHR11205 6 158 5.3E-70 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 PIRSF PIRSF002122 2 158 6.7E-51 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 SUPERFAMILY SSF47973 5 151 8.24E-54 T 22-04-2016 IPR023798 Ribosomal protein S7 domain MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 Pfam PF00177 Ribosomal protein S7p/S5e 2 151 3.4E-60 T 22-04-2016 IPR023798 Ribosomal protein S7 domain MED134_RS12220 d1e959a7f31ce814dbea09d82ffdc4ba 158 Gene3D G3DSA:1.10.455.10 6 158 1.8E-59 T 22-04-2016 IPR023798 Ribosomal protein S7 domain MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 Gene3D G3DSA:3.20.20.140 35 434 4.4E-122 T 22-04-2016 MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 SUPERFAMILY SSF51556 33 283 1.05E-91 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 SUPERFAMILY SSF51556 350 433 1.05E-91 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 PANTHER PTHR10443 32 283 8.4E-97 T 22-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 PANTHER PTHR10443 349 434 8.4E-97 T 22-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 MED134_RS01650 5205c1f25fb13bce9a91923d9cdca038 435 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 40 425 1.5E-98 T 22-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 Pfam PF01274 Malate synthase 12 530 4.4E-201 T 22-04-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 PIRSF PIRSF001363 3 531 9.0E-241 T 22-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 PANTHER PTHR21631:SF1 1 531 2.8E-261 T 22-04-2016 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 531 7.2E-235 T 22-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 SUPERFAMILY SSF51645 6 531 1.57E-189 T 22-04-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 22-04-2016 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 PANTHER PTHR21631 1 531 2.8E-261 T 22-04-2016 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 Gene3D G3DSA:1.20.1220.12 414 525 4.9E-26 T 22-04-2016 MED134_RS05545 4efb3fc8ffb764ec734bff3026a2b5d1 531 Gene3D G3DSA:3.20.20.360 72 413 1.6E-113 T 22-04-2016 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 224 4.5E-43 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 PANTHER PTHR21600 1 260 9.0E-125 T 22-04-2016 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 Pfam PF00849 RNA pseudouridylate synthase 68 195 3.8E-14 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 SUPERFAMILY SSF55174 8 60 3.09E-14 T 22-04-2016 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 SMART SM00363 7 69 7.0E-10 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 SUPERFAMILY SSF55120 64 229 5.18E-38 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 PANTHER PTHR21600:SF24 1 260 9.0E-125 T 22-04-2016 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 Gene3D G3DSA:3.10.290.10 6 68 4.4E-23 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS01240 9b016b2a64241af140f190a9f4572b46 260 Pfam PF01479 S4 domain 8 52 3.9E-11 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 100 348 7.4E-95 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 Pfam PF01883 Domain of unknown function DUF59 5 58 2.8E-8 T 22-04-2016 IPR002744 Domain of unknown function DUF59 MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 SUPERFAMILY SSF52540 102 352 8.09E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 PANTHER PTHR23264 1 378 2.1E-133 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 PANTHER PTHR23264:SF19 1 378 2.1E-133 T 22-04-2016 MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 22-04-2016 IPR000808 Mrp, conserved site GO:0005524 MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 Gene3D G3DSA:3.40.50.300 90 347 4.4E-95 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 SUPERFAMILY SSF117916 1 97 1.08E-12 T 22-04-2016 MED134_RS10790 b8b0f33603f915a75ffa1fded0d61191 378 Hamap MF_02040 Iron-sulfur cluster carrier protein. 95 349 35.311 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 Gene3D G3DSA:3.60.21.10 8 131 2.5E-21 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 Gene3D G3DSA:3.60.21.10 194 248 2.5E-21 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 PANTHER PTHR34990:SF1 7 250 1.8E-43 T 22-04-2016 MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 SUPERFAMILY SSF56300 7 237 4.49E-24 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 PANTHER PTHR34990 7 250 1.8E-43 T 22-04-2016 MED134_RS08830 c381107ed5971a46937515b04d28b5bb 253 Pfam PF00149 Calcineurin-like phosphoesterase 8 213 1.9E-5 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 PANTHER PTHR26402 3 116 6.0E-27 T 22-04-2016 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 Pfam PF04397 LytTr DNA-binding domain 151 241 6.2E-18 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 Gene3D G3DSA:3.40.50.2300 3 125 3.5E-26 T 22-04-2016 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 SMART SM00850 148 244 6.2E-22 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 Gene3D G3DSA:2.40.50.40 140 208 3.2E-18 T 22-04-2016 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 SMART SM00448 3 113 7.3E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 SUPERFAMILY SSF52172 4 125 7.68E-26 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07550 6e97fae310db19e903d76ae62cffa621 244 Pfam PF00072 Response regulator receiver domain 6 113 3.6E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 SUPERFAMILY SSF56542 241 422 7.59E-87 T 22-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 SUPERFAMILY SSF56542 4 121 7.59E-87 T 22-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 28 396 1.5E-98 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 396 2.3E-89 T 22-04-2016 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PANTHER PTHR10572 5 400 2.4E-118 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PANTHER PTHR10572:SF6 5 400 2.4E-118 T 22-04-2016 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 SUPERFAMILY SSF55035 115 231 1.33E-18 T 22-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 324 345 5.3E-6 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 79 99 5.3E-6 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 175 193 5.3E-6 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 52 73 5.3E-6 T 22-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 Gene3D G3DSA:3.30.70.420 120 230 3.6E-24 T 22-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 Gene3D G3DSA:3.90.770.10 4 119 3.5E-82 T 22-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS06470 59e39b6fd401237f7633d769ae1db152 437 Gene3D G3DSA:3.90.770.10 246 385 3.5E-82 T 22-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 SUPERFAMILY SSF56235 221 310 2.08E-37 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 SUPERFAMILY SSF56235 37 66 2.08E-37 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 SUPERFAMILY SSF56235 92 193 2.08E-37 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 Gene3D G3DSA:3.60.20.10 8 309 2.2E-47 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 Gene3D G3DSA:3.40.50.2020 336 530 7.1E-21 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 PANTHER PTHR11907:SF0 112 382 1.5E-69 T 22-04-2016 MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 PANTHER PTHR11907:SF0 401 522 1.5E-69 T 22-04-2016 MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 PANTHER PTHR11907 112 382 1.5E-69 T 22-04-2016 MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 PANTHER PTHR11907 401 522 1.5E-69 T 22-04-2016 MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 SUPERFAMILY SSF53271 320 396 2.32E-18 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08975 e94c2f13d0bbea13bc3fe0547dad7fa0 632 SUPERFAMILY SSF53271 426 521 2.32E-18 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SUPERFAMILY SSF52172 1 131 3.56E-37 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SMART SM00448 2 115 3.3E-40 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Gene3D G3DSA:3.40.50.2300 2 130 2.6E-38 T 22-04-2016 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SMART SM00419 288 340 2.4E-4 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Gene3D G3DSA:1.10.10.10 274 346 2.0E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Pfam PF00027 Cyclic nucleotide-binding domain 159 244 3.4E-14 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Pfam PF00072 Response regulator receiver domain 4 116 3.4E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SMART SM00100 140 257 4.8E-7 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SUPERFAMILY SSF51206 146 272 2.23E-30 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 SUPERFAMILY SSF46785 274 346 2.2E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 PANTHER PTHR26402 2 137 2.9E-43 T 22-04-2016 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Pfam PF13545 Crp-like helix-turn-helix domain 280 346 1.4E-10 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MED134_RS04650 0c1d291b4579c84e80ae9532f344082c 348 Gene3D G3DSA:2.60.120.10 145 271 9.1E-24 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS04895 352e978d33702e41c6b943aeef7418e2 173 SUPERFAMILY SSF160369 1 171 1.96E-44 T 22-04-2016 MED134_RS04895 352e978d33702e41c6b943aeef7418e2 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 168 9.0E-5 T 22-04-2016 MED134_RS04895 352e978d33702e41c6b943aeef7418e2 173 PANTHER PTHR11560 1 172 2.9E-35 T 22-04-2016 MED134_RS04895 352e978d33702e41c6b943aeef7418e2 173 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 161 19.086 T 22-04-2016 IPR022973 Ribosomal protein L10 MED134_RS04895 352e978d33702e41c6b943aeef7418e2 173 Pfam PF00466 Ribosomal protein L10 1 100 4.7E-19 T 22-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 PANTHER PTHR10681 303 434 1.9E-21 T 22-04-2016 MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 Gene3D G3DSA:3.40.30.10 2 28 4.7E-41 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 Gene3D G3DSA:3.40.30.10 312 454 4.7E-41 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 PANTHER PTHR10681:SF68 303 434 1.9E-21 T 22-04-2016 MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 SUPERFAMILY SSF52833 314 450 1.48E-27 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS08250 54e873355bce48d1b4301a4d7d1459a4 457 Pfam PF00578 AhpC/TSA family 316 435 3.1E-16 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Gene3D G3DSA:2.120.10.90 495 810 5.6E-120 T 22-04-2016 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 469 5.1E-160 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 810 0.0 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Gene3D G3DSA:3.90.199.10 29 234 2.8E-120 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Gene3D G3DSA:3.90.199.10 331 396 2.8E-120 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 813 29.252 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 656 7.1E-9 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 763 809 5.7E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 667 708 5.4E-9 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 599 1.3E-5 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 546 2.0E-10 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 713 759 7.0E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 PANTHER PTHR10169:SF48 1 779 0.0 T 22-04-2016 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 SMART SM00434 10 462 6.5E-281 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 PANTHER PTHR10169 1 779 0.0 T 22-04-2016 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 SUPERFAMILY SSF56719 29 483 1.44E-178 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 SUPERFAMILY SSF101904 496 820 4.58E-101 T 22-04-2016 MED134_RS01970 043b6b669543fd871ce8b7a098b6b358 848 Gene3D G3DSA:3.30.1360.40 235 330 4.0E-37 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain MED134_RS00170 cf92ff0550973bcce18b379767b9178a 199 Pfam PF08818 Domain of unknown function (DU1801) 21 113 1.8E-14 T 22-04-2016 IPR014922 Domain of unknown function DUF1801 MED134_RS00170 cf92ff0550973bcce18b379767b9178a 199 SUPERFAMILY SSF159888 17 121 1.1E-22 T 22-04-2016 MED134_RS00170 cf92ff0550973bcce18b379767b9178a 199 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 189 4.4E-12 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 27 437 2.0E-94 T 22-04-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Gene3D G3DSA:1.10.3550.10 358 441 5.1E-31 T 22-04-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Gene3D G3DSA:1.10.3550.10 121 154 5.1E-31 T 22-04-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Gene3D G3DSA:1.10.3410.10 256 357 7.8E-31 T 22-04-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 SMART SM00471 60 266 1.3E-9 T 22-04-2016 IPR003607 HD/PDEase domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 PANTHER PTHR11373 156 381 6.4E-62 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 PANTHER PTHR11373 1 140 6.4E-62 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 PANTHER PTHR11373:SF29 156 381 6.4E-62 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 PANTHER PTHR11373:SF29 1 140 6.4E-62 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Pfam PF01966 HD domain 64 134 9.1E-10 T 22-04-2016 IPR006674 HD domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Gene3D G3DSA:1.10.3210.10 1 120 3.4E-67 T 22-04-2016 IPR006674 HD domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 Gene3D G3DSA:1.10.3210.10 157 255 3.4E-67 T 22-04-2016 IPR006674 HD domain MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 SUPERFAMILY SSF109604 18 194 3.71E-62 T 22-04-2016 MED134_RS11035 8e705ac221ccf17bfcb3f6609adca19c 443 SUPERFAMILY SSF109604 235 408 3.71E-62 T 22-04-2016 MED134_RS10390 954dee3dbc5c763a0c4b31cb10815e8b 160 Pfam PF03795 YCII-related domain 74 151 1.7E-5 T 22-04-2016 IPR005545 YCII-related MED134_RS10390 954dee3dbc5c763a0c4b31cb10815e8b 160 Gene3D G3DSA:3.30.70.1060 68 151 2.2E-6 T 22-04-2016 MED134_RS10390 954dee3dbc5c763a0c4b31cb10815e8b 160 SUPERFAMILY SSF54909 58 152 2.95E-7 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS10485 02c8053989478bf6413021f8d3594b1e 278 Gene3D G3DSA:2.60.40.670 40 121 9.2E-18 T 22-04-2016 IPR000601 PKD domain MED134_RS10485 02c8053989478bf6413021f8d3594b1e 278 Pfam PF00801 PKD domain 63 108 2.3E-7 T 22-04-2016 IPR000601 PKD domain MED134_RS10485 02c8053989478bf6413021f8d3594b1e 278 Gene3D G3DSA:2.60.120.260 130 267 1.0E-4 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS10485 02c8053989478bf6413021f8d3594b1e 278 SUPERFAMILY SSF49299 39 119 5.36E-17 T 22-04-2016 IPR000601 PKD domain MED134_RS10485 02c8053989478bf6413021f8d3594b1e 278 SMART SM00089 42 119 9.8E-7 T 22-04-2016 IPR022409 PKD/Chitinase domain MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 SUPERFAMILY SSF47384 234 303 3.53E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 SMART SM00388 241 309 6.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 SMART SM00387 354 464 6.3E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 464 6.8E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 Gene3D G3DSA:1.10.287.130 236 293 9.4E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 PANTHER PTHR24423 239 464 3.7E-49 T 22-04-2016 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 302 4.3E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 Gene3D G3DSA:3.30.565.10 294 464 1.4E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 SUPERFAMILY SSF55874 310 464 3.67E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 5.3E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 5.3E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 5.3E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14375 aa55f1028333964ce6827c807e371a1b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 5.3E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS01320 36514616dea8bc9619c70826c0776a15 184 Pfam PF01553 Acyltransferase 26 137 1.0E-10 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS01320 36514616dea8bc9619c70826c0776a15 184 PANTHER PTHR10434 10 158 2.4E-34 T 22-04-2016 MED134_RS01320 36514616dea8bc9619c70826c0776a15 184 SMART SM00563 29 141 1.1E-16 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS01320 36514616dea8bc9619c70826c0776a15 184 PANTHER PTHR10434:SF9 10 158 2.4E-34 T 22-04-2016 MED134_RS01320 36514616dea8bc9619c70826c0776a15 184 SUPERFAMILY SSF69593 13 160 4.97E-17 T 22-04-2016 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 Gene3D G3DSA:3.40.50.1100 41 139 1.2E-32 T 22-04-2016 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 TIGRFAM TIGR01138 cysM: cysteine synthase B 4 291 3.6E-121 T 22-04-2016 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 291 7.0E-109 T 22-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 280 8.4E-71 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 SUPERFAMILY SSF53686 4 287 4.98E-89 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 PANTHER PTHR10314:SF100 4 292 1.8E-126 T 22-04-2016 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 Gene3D G3DSA:3.40.50.1100 145 291 4.4E-79 T 22-04-2016 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 Gene3D G3DSA:3.40.50.1100 3 40 4.4E-79 T 22-04-2016 MED134_RS12625 35ed05b3ac16c9b24607602ce001869a 292 PANTHER PTHR10314 4 292 1.8E-126 T 22-04-2016 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SMART SM00631 175 490 4.4E-21 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 Gene3D G3DSA:3.40.630.10 170 514 9.8E-60 T 22-04-2016 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 PANTHER PTHR11705:SF56 225 457 4.0E-37 T 22-04-2016 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SMART SM00137 846 1024 6.1E-5 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 Pfam PF00629 MAM domain, meprin/A5/mu 1199 1366 8.4E-13 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 Pfam PF00629 MAM domain, meprin/A5/mu 853 1011 4.8E-17 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SUPERFAMILY SSF53187 171 513 3.1E-45 T 22-04-2016 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 Pfam PF00246 Zinc carboxypeptidase 226 426 1.3E-36 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 PANTHER PTHR11705 225 457 4.0E-37 T 22-04-2016 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 1940 2017 2.0E-12 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SUPERFAMILY SSF49899 1194 1366 5.38E-24 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 Gene3D G3DSA:2.60.40.10 1096 1180 2.0E-10 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SUPERFAMILY SSF49899 851 1012 1.74E-23 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SUPERFAMILY SSF49265 1090 1185 6.81E-13 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS04700 fcfec7b32604eff9f2443f5b2a788c59 2017 SMART SM00060 1095 1169 9.9E-5 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Gene3D G3DSA:3.30.70.20 279 338 1.0E-7 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Pfam PF13746 4Fe-4S dicluster domain 214 323 1.0E-43 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 PANTHER PTHR30176 12 368 1.0E-81 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 352 469 1.5E-17 T 22-04-2016 IPR032879 FixG, C-terminal immunoglobulin-like domain MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 34 458 3.5E-129 T 22-04-2016 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 PANTHER PTHR30176:SF2 12 368 1.0E-81 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Gene3D G3DSA:2.60.40.10 353 470 7.2E-15 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 270 281 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Gene3D G3DSA:1.10.1060.10 218 278 2.3E-10 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 SUPERFAMILY SSF54862 99 120 1.19E-22 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 SUPERFAMILY SSF54862 189 353 1.19E-22 T 22-04-2016 MED134_RS04575 0e08f5cf7ac20ad7092e685c23868dc2 473 Pfam PF12801 4Fe-4S binding domain 89 137 6.5E-14 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS04215 f134bc816817fddd99f78204d1d4cf26 825 SUPERFAMILY SSF49464 21 117 3.53E-13 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS04215 f134bc816817fddd99f78204d1d4cf26 825 Gene3D G3DSA:2.60.40.1120 21 116 7.0E-12 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS04215 f134bc816817fddd99f78204d1d4cf26 825 PANTHER PTHR11532 1 109 1.5E-13 T 22-04-2016 MED134_RS04215 f134bc816817fddd99f78204d1d4cf26 825 PANTHER PTHR11532:SF57 1 109 1.5E-13 T 22-04-2016 MED134_RS04215 f134bc816817fddd99f78204d1d4cf26 825 Pfam PF13715 CarboxypepD_reg-like domain 21 109 7.0E-16 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Gene3D G3DSA:3.10.580.10 129 262 9.0E-25 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SUPERFAMILY SSF158791 6 133 3.27E-27 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Gene3D G3DSA:1.10.357.20 277 448 7.0E-48 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Pfam PF00571 CBS domain 205 255 2.3E-6 T 22-04-2016 IPR000644 CBS domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Pfam PF00571 CBS domain 137 193 2.2E-8 T 22-04-2016 IPR000644 CBS domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SMART SM00924 32 136 1.4E-25 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 PANTHER PTHR11911:SF23 70 85 1.8E-37 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 PANTHER PTHR11911:SF23 123 422 1.8E-37 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 PANTHER PTHR11911 70 85 1.8E-37 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 PANTHER PTHR11911 123 422 1.8E-37 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Pfam PF03448 MgtE intracellular N domain 32 134 1.4E-21 T 22-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Pfam PF01769 Divalent cation transporter 320 441 2.1E-27 T 22-04-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SMART SM00116 207 255 2.4E-4 T 22-04-2016 IPR000644 CBS domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SMART SM00116 143 196 6.6 T 22-04-2016 IPR000644 CBS domain MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SUPERFAMILY SSF54631 136 270 1.26E-29 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 SUPERFAMILY SSF161093 276 447 5.75E-44 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 Gene3D G3DSA:1.25.60.10 2 128 7.6E-28 T 22-04-2016 MED134_RS08260 d4b0def4db6efa561ad9f5c20cacf0a2 449 TIGRFAM TIGR00400 mgtE: magnesium transporter 23 448 3.8E-99 T 22-04-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MED134_RS02375 c3c68de5d2607d13035fffce734730c2 303 Pfam PF01029 NusB family 195 287 2.5E-20 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MED134_RS02375 c3c68de5d2607d13035fffce734730c2 303 Gene3D G3DSA:1.10.940.10 189 286 2.4E-34 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MED134_RS02375 c3c68de5d2607d13035fffce734730c2 303 PANTHER PTHR11078 35 303 6.0E-19 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 MED134_RS02375 c3c68de5d2607d13035fffce734730c2 303 SUPERFAMILY SSF48013 194 291 8.5E-22 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MED134_RS07180 f375bb4d1cf06f7ff42b73ffd6409324 176 PANTHER PTHR10681 1 152 4.9E-13 T 22-04-2016 MED134_RS07180 f375bb4d1cf06f7ff42b73ffd6409324 176 SUPERFAMILY SSF52833 1 164 1.32E-32 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS07180 f375bb4d1cf06f7ff42b73ffd6409324 176 Pfam PF00578 AhpC/TSA family 6 133 2.3E-19 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS07180 f375bb4d1cf06f7ff42b73ffd6409324 176 Gene3D G3DSA:3.40.30.10 1 155 1.7E-22 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953:SF28 353 562 2.1E-85 T 22-04-2016 MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953:SF28 221 322 2.1E-85 T 22-04-2016 MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953:SF28 52 196 2.1E-85 T 22-04-2016 MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 SUPERFAMILY SSF56300 153 322 1.94E-24 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 SUPERFAMILY SSF56300 355 383 1.94E-24 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 SUPERFAMILY SSF56300 449 560 1.94E-24 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 Pfam PF09423 PhoD-like phosphatase 155 559 1.7E-108 T 22-04-2016 IPR018946 Alkaline phosphatase D-related MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 55 144 4.1E-21 T 22-04-2016 IPR032093 Phospholipase D, N-terminal MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 Gene3D G3DSA:3.60.21.10 166 372 2.1E-10 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953 353 562 2.1E-85 T 22-04-2016 MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953 221 322 2.1E-85 T 22-04-2016 MED134_RS05750 2e4166a5dba0623985d33c1b5a7c67a0 580 PANTHER PTHR22953 52 196 2.1E-85 T 22-04-2016 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 SMART SM00448 3 113 8.3E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 Pfam PF04397 LytTr DNA-binding domain 154 243 2.3E-13 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 Gene3D G3DSA:2.40.50.40 143 213 2.4E-15 T 22-04-2016 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 SUPERFAMILY SSF52172 3 129 1.71E-26 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 PANTHER PTHR26402 3 118 1.2E-25 T 22-04-2016 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 SMART SM00850 152 246 2.0E-18 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 Pfam PF00072 Response regulator receiver domain 7 113 1.4E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS06985 781310d1b2d8d8fd64685c9cf93df050 248 Gene3D G3DSA:3.40.50.2300 2 127 1.2E-26 T 22-04-2016 MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 PRINTS PR00689 Acyl-coA-binding protein signature 68 85 1.5E-6 T 22-04-2016 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 PRINTS PR00689 Acyl-coA-binding protein signature 7 22 1.5E-6 T 22-04-2016 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 PRINTS PR00689 Acyl-coA-binding protein signature 24 42 1.5E-6 T 22-04-2016 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 SUPERFAMILY SSF47027 6 85 9.16E-20 T 22-04-2016 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 Gene3D G3DSA:1.20.80.10 7 85 3.6E-18 T 22-04-2016 IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle MED134_RS05835 9f0c82f9ac378199211fe1ff2151c5e0 86 Pfam PF00887 Acyl CoA binding protein 8 85 4.3E-15 T 22-04-2016 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 48 227 1.7E-51 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 PIRSF PIRSF016262 1 237 1.1E-59 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 SUPERFAMILY SSF55681 3 229 7.87E-61 T 22-04-2016 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 Hamap MF_00013 Octanoyltransferase [lipB]. 4 230 33.963 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 PANTHER PTHR10993 5 232 3.1E-76 T 22-04-2016 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 Gene3D G3DSA:3.90.1550.10 3 228 1.7E-68 T 22-04-2016 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 Pfam PF03099 Biotin/lipoate A/B protein ligase family 71 181 4.0E-8 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 88 103 - T 22-04-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 MED134_RS11660 f416817e2a3b28298af1b78ba0bbd807 238 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 92 145 3.0E-14 T 22-04-2016 MED134_RS09760 a151a247e462f592e082a2b160a7807f 122 Pfam PF12680 SnoaL-like domain 11 112 3.3E-10 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain MED134_RS09760 a151a247e462f592e082a2b160a7807f 122 SUPERFAMILY SSF54427 1 119 1.61E-20 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS09760 a151a247e462f592e082a2b160a7807f 122 Gene3D G3DSA:3.10.450.50 2 117 1.2E-12 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 SUPERFAMILY SSF54637 529 689 5.69E-28 T 22-04-2016 IPR029069 HotDog domain MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 Gene3D G3DSA:3.40.605.10 4 239 9.7E-31 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 Gene3D G3DSA:3.10.129.10 524 691 3.8E-35 T 22-04-2016 IPR029069 HotDog domain MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 Gene3D G3DSA:3.40.309.10 257 453 8.2E-35 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 3 661 7.3E-258 T 22-04-2016 IPR011966 Phenylacetic acid degradation protein PaaN MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 Pfam PF01575 MaoC like domain 539 640 5.4E-18 T 22-04-2016 IPR002539 MaoC-like domain MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 SUPERFAMILY SSF53720 3 502 8.64E-72 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 PANTHER PTHR11699:SF12 5 522 7.9E-131 T 22-04-2016 IPR011966 Phenylacetic acid degradation protein PaaN MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 Pfam PF00171 Aldehyde dehydrogenase family 11 499 2.2E-52 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS11535 fd71e84c22d4bc34cda3dbac98025cd3 845 PANTHER PTHR11699 5 522 7.9E-131 T 22-04-2016 MED134_RS02315 074855f1b98f472c44fadad6ebb51092 488 Pfam PF00158 Sigma-54 interaction domain 167 227 3.4E-4 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MED134_RS02315 074855f1b98f472c44fadad6ebb51092 488 Gene3D G3DSA:3.40.50.300 40 246 5.2E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02315 074855f1b98f472c44fadad6ebb51092 488 PANTHER PTHR30267 1 467 5.5E-125 T 22-04-2016 MED134_RS02315 074855f1b98f472c44fadad6ebb51092 488 PANTHER PTHR30267:SF3 1 467 5.5E-125 T 22-04-2016 MED134_RS02315 074855f1b98f472c44fadad6ebb51092 488 SUPERFAMILY SSF52540 40 332 3.39E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08460 2a335eb07876110a05f4b93be8f1d218 342 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 5 327 8.0E-139 T 22-04-2016 IPR026360 Putative exonuclease, DNA ligase-associated MED134_RS08460 2a335eb07876110a05f4b93be8f1d218 342 SUPERFAMILY SSF56281 15 319 5.39E-58 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS08460 2a335eb07876110a05f4b93be8f1d218 342 PANTHER PTHR11203:SF35 12 203 1.7E-51 T 22-04-2016 MED134_RS08460 2a335eb07876110a05f4b93be8f1d218 342 PANTHER PTHR11203 12 203 1.7E-51 T 22-04-2016 MED134_RS08460 2a335eb07876110a05f4b93be8f1d218 342 Gene3D G3DSA:3.60.15.10 17 183 5.2E-17 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 260 4.0E-98 T 22-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 PANTHER PTHR13847:SF5 4 360 1.1E-68 T 22-04-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 265 357 7.7E-26 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 SUPERFAMILY SSF101790 273 362 9.16E-26 T 22-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 362 6.2E-119 T 22-04-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 SUPERFAMILY SSF103025 1 281 2.2E-98 T 22-04-2016 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 PIRSF PIRSF006487 1 363 7.1E-99 T 22-04-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Gene3D G3DSA:3.30.70.1400 52 141 9.9E-31 T 22-04-2016 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 PANTHER PTHR13847 4 360 1.1E-68 T 22-04-2016 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Gene3D G3DSA:3.30.1360.120 2 51 2.1E-51 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Gene3D G3DSA:3.30.1360.120 142 237 2.1E-51 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Gene3D G3DSA:2.40.30.110 280 357 5.7E-30 T 22-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS00100 8bcf335f3bb93c4d0779bce47c804399 363 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 363 43.271 T 22-04-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 SMART SM00257 228 271 4.5E-15 T 22-04-2016 IPR018392 LysM domain MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 Gene3D G3DSA:3.10.350.10 228 271 1.3E-17 T 22-04-2016 IPR018392 LysM domain MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 SUPERFAMILY SSF54106 228 270 1.96E-12 T 22-04-2016 IPR018392 LysM domain MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 PANTHER PTHR33308 71 208 8.5E-18 T 22-04-2016 MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 77 204 8.3E-22 T 22-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 PANTHER PTHR33308:SF3 71 208 8.5E-18 T 22-04-2016 MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 Pfam PF01476 LysM domain 229 270 2.8E-14 T 22-04-2016 IPR018392 LysM domain MED134_RS11595 75b0236a3c15d09630b3b5a37bb94888 277 SMART SM00047 65 208 1.2E-31 T 22-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 169 380 1.4E-62 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 Gene3D G3DSA:3.40.50.1770 262 343 2.6E-17 T 22-04-2016 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 SUPERFAMILY SSF51735 165 329 3.03E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 PANTHER PTHR10160 28 391 2.9E-104 T 22-04-2016 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 201 226 - T 22-04-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 Gene3D G3DSA:3.40.50.720 208 261 2.1E-6 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 SMART SM01003 32 165 3.4E-46 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 Gene3D G3DSA:3.40.50.1770 30 207 4.0E-52 T 22-04-2016 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 SUPERFAMILY SSF52283 30 165 9.35E-43 T 22-04-2016 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 SUPERFAMILY SSF52283 332 388 9.35E-43 T 22-04-2016 MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 SMART SM01002 177 324 1.1E-60 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MED134_RS14565 b9d133fecd13a2c3729064632d3b5999 399 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 32 165 1.6E-37 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MED134_RS02335 645439467068c4c43bd97f5275a71486 227 Pfam PF10677 Protein of unknown function (DUF2490) 28 211 1.5E-46 T 22-04-2016 IPR019619 Protein of unknown function DUF2490 MED134_RS03045 16aa803b7eefa31e25ca73f7a4faa6eb 358 Pfam PF12725 Protein of unknown function (DUF3810) 35 348 1.2E-97 T 22-04-2016 IPR024294 Protein of unknown function DUF3810 MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 SUPERFAMILY SSF63829 202 349 1.8E-15 T 22-04-2016 MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 199 220 0.014 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 322 344 0.0011 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 238 260 7.1E-5 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 60 80 6.1E-4 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 148 168 5.7E-4 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Pfam PF07494 Two component regulator propeller 99 121 1.3E-5 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Gene3D G3DSA:2.120.10.30 265 345 7.5E-6 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Gene3D G3DSA:2.120.10.30 197 264 1.6E-7 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 SUPERFAMILY SSF63829 57 187 1.63E-10 T 22-04-2016 MED134_RS03730 ff094818896bb1d0ffd47f9703d51313 366 Gene3D G3DSA:2.120.10.30 69 170 1.1E-8 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 Pfam PF10150 Ribonuclease E/G family 143 413 3.7E-97 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 PANTHER PTHR30001:SF0 1 507 1.3E-139 T 22-04-2016 MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 SUPERFAMILY SSF50249 39 147 1.06E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 15 427 1.9E-120 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 PANTHER PTHR30001 1 507 1.3E-139 T 22-04-2016 MED134_RS10235 387c3752332f8303cdeedc4c9447c69a 516 Gene3D G3DSA:2.40.50.140 32 147 1.0E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08520 1aa1c77a65164cea775f8effdde9526f 400 SUPERFAMILY SSF56601 53 391 2.29E-71 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08520 1aa1c77a65164cea775f8effdde9526f 400 Pfam PF00144 Beta-lactamase 62 376 2.6E-49 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS08520 1aa1c77a65164cea775f8effdde9526f 400 PANTHER PTHR22935 55 392 6.0E-65 T 22-04-2016 MED134_RS08520 1aa1c77a65164cea775f8effdde9526f 400 Gene3D G3DSA:3.40.710.10 54 386 1.9E-75 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 Pfam PF00691 OmpA family 21 100 6.3E-10 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 Pfam PF00691 OmpA family 171 267 7.1E-11 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 SUPERFAMILY SSF103088 162 273 3.66E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 Gene3D G3DSA:3.30.1330.60 17 125 5.3E-19 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 Gene3D G3DSA:3.30.1330.60 160 274 4.5E-21 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 PRINTS PR01021 OMPA domain signature 22 44 2.6E-8 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 PRINTS PR01021 OMPA domain signature 52 67 2.6E-8 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 PRINTS PR01021 OMPA domain signature 67 83 2.6E-8 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 SUPERFAMILY SSF103088 15 125 1.11E-17 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 PANTHER PTHR30128:SF16 21 234 1.2E-12 T 22-04-2016 MED134_RS09070 e34228be3ee526edb59354ba2abb1a8a 285 PANTHER PTHR30128 21 234 1.2E-12 T 22-04-2016 MED134_RS09350 01bf6a86ba7e66faffa3519f64b3aec3 317 Pfam PF03060 Nitronate monooxygenase 6 316 2.9E-34 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MED134_RS09350 01bf6a86ba7e66faffa3519f64b3aec3 317 Gene3D G3DSA:3.20.20.70 7 257 5.3E-46 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS09350 01bf6a86ba7e66faffa3519f64b3aec3 317 PANTHER PTHR32332 3 317 4.9E-54 T 22-04-2016 MED134_RS09350 01bf6a86ba7e66faffa3519f64b3aec3 317 SUPERFAMILY SSF51412 5 280 7.02E-48 T 22-04-2016 MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806:SF2 333 367 8.4E-110 T 22-04-2016 MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806:SF2 470 548 8.4E-110 T 22-04-2016 MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806:SF2 1 317 8.4E-110 T 22-04-2016 MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 Pfam PF01145 SPFH domain / Band 7 family 32 235 4.1E-14 T 22-04-2016 IPR001107 Band 7 domain MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806 333 367 8.4E-110 T 22-04-2016 IPR027705 Flotillin family MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806 470 548 8.4E-110 T 22-04-2016 IPR027705 Flotillin family MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 PANTHER PTHR13806 1 317 8.4E-110 T 22-04-2016 IPR027705 Flotillin family MED134_RS05340 0dcfd24f500b523dc4aaa8343e1e1a24 688 SUPERFAMILY SSF117892 58 180 2.75E-10 T 22-04-2016 IPR001107 Band 7 domain MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 SUPERFAMILY SSF52242 415 547 1.83E-42 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Pfam PF00809 Pterin binding enzyme 28 266 1.5E-53 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 SUPERFAMILY SSF47644 318 404 1.7E-26 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Pfam PF02310 B12 binding domain 419 512 4.1E-20 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 SMART SM01018 322 405 3.6E-40 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Pfam PF02607 B12 binding domain 325 397 6.5E-24 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 PIRSF PIRSF000381 2 867 0.0 T 22-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 609 880 7.7E-124 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Gene3D G3DSA:3.20.20.20 24 304 6.0E-111 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Gene3D G3DSA:3.40.50.280 415 564 1.9E-60 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 SUPERFAMILY SSF56507 572 894 4.32E-119 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Gene3D G3DSA:3.10.196.10 629 894 2.4E-104 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 TIGRFAM TIGR02082 metH: methionine synthase 4 863 0.0 T 22-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 Gene3D G3DSA:1.10.1240.10 315 402 2.0E-35 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain MED134_RS07085 6ee255acdf9eea25f4ff67edbf981d8e 896 SUPERFAMILY SSF51717 24 298 5.36E-86 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 SUPERFAMILY SSF55021 189 267 5.29E-19 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 PANTHER PTHR21022:SF0 1 267 2.1E-73 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 Gene3D G3DSA:3.40.190.10 88 166 1.2E-24 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 Gene3D G3DSA:3.30.70.260 189 270 2.1E-19 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 PANTHER PTHR21022 1 267 2.1E-73 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 Gene3D G3DSA:3.40.190.10 1 87 1.6E-24 T 22-04-2016 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 Pfam PF00800 Prephenate dehydratase 3 180 3.4E-52 T 22-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 MED134_RS05620 bc6bf20e247ff81a2553416831f4ec95 272 SUPERFAMILY SSF53850 1 182 1.52E-53 T 22-04-2016 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 Pfam PF13167 GTP-binding GTPase N-terminal 29 116 1.0E-33 T 22-04-2016 IPR025121 GTPase HflX, N-terminal MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 200 330 5.9E-13 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 378 8.5E-133 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 PANTHER PTHR10229 8 383 1.3E-157 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 Gene3D G3DSA:3.40.50.300 199 383 3.1E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 Hamap MF_00900 GTPase HflX [hflX]. 31 401 44.068 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 SUPERFAMILY SSF52540 200 383 7.45E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 Pfam PF16360 GTP-binding GTPase Middle Region 118 196 4.6E-30 T 22-04-2016 IPR032305 GTP-binding protein, middle domain MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 PIRSF PIRSF006809 3 393 5.6E-135 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 222 3.7E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 3.7E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 Pfam PF01926 50S ribosome-binding GTPase 201 319 2.6E-22 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS07675 8a04e216f7205e9e00004bfdfbaeba01 408 PANTHER PTHR10229:SF0 8 383 1.3E-157 T 22-04-2016 MED134_RS03170 3edfbe175eb4fb6009915a8710697a19 333 Pfam PF00491 Arginase family 46 321 2.4E-25 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS03170 3edfbe175eb4fb6009915a8710697a19 333 Gene3D G3DSA:3.40.800.10 21 326 2.8E-54 T 22-04-2016 IPR023696 Ureohydrolase domain MED134_RS03170 3edfbe175eb4fb6009915a8710697a19 333 SUPERFAMILY SSF52768 38 325 5.4E-48 T 22-04-2016 MED134_RS03170 3edfbe175eb4fb6009915a8710697a19 333 PANTHER PTHR11358 54 263 9.9E-16 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS03360 d345a4ec44ecf62d62e7e355b67e1b16 230 PANTHER PTHR33706:SF1 103 222 5.0E-12 T 22-04-2016 MED134_RS03360 d345a4ec44ecf62d62e7e355b67e1b16 230 PANTHER PTHR33706 103 222 5.0E-12 T 22-04-2016 MED134_RS03360 d345a4ec44ecf62d62e7e355b67e1b16 230 Gene3D G3DSA:2.20.110.10 100 226 1.1E-14 T 22-04-2016 MED134_RS03360 d345a4ec44ecf62d62e7e355b67e1b16 230 SUPERFAMILY SSF82185 98 213 2.16E-18 T 22-04-2016 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 Pfam PF04055 Radical SAM superfamily 44 117 1.2E-9 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 SUPERFAMILY SSF102114 33 117 6.54E-8 T 22-04-2016 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 PIRSF PIRSF000370 17 213 4.3E-52 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 Gene3D G3DSA:3.20.20.70 45 117 9.6E-8 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 19 213 35.431 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 PANTHER PTHR11228:SF6 4 212 3.5E-25 T 22-04-2016 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 PANTHER PTHR11228 4 212 3.5E-25 T 22-04-2016 MED134_RS12760 1948beaab74819db660a8bc40d565c03 213 Pfam PF13394 4Fe-4S single cluster domain 40 125 1.2E-14 T 22-04-2016 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 27 43 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 157 186 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 84 108 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 260 286 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 232 259 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 120 142 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PRINTS PR00073 Coprogen oxidase signature 44 65 2.4E-83 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 SUPERFAMILY SSF102886 2 300 3.27E-126 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PANTHER PTHR10755 1 301 2.6E-172 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 Gene3D G3DSA:3.40.1500.10 1 300 1.4E-131 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 PIRSF PIRSF000166 1 301 4.7E-128 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS08700 f2eb37375ccfef13c3ba7ffafb920605 301 Pfam PF01218 Coproporphyrinogen III oxidase 6 300 1.7E-134 T 22-04-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 SMART SM00245 161 348 1.4E-52 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 SUPERFAMILY SSF50156 63 177 2.83E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 SMART SM00228 91 161 5.6E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Gene3D G3DSA:3.90.226.10 376 388 4.9E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Gene3D G3DSA:3.90.226.10 171 341 4.9E-60 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 PANTHER PTHR32060 36 343 4.2E-92 T 22-04-2016 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 48 342 2.7E-81 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Gene3D G3DSA:2.30.42.10 97 170 7.4E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Pfam PF13180 PDZ domain 92 169 1.5E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Gene3D G3DSA:3.30.750.44 50 96 5.2E-7 T 22-04-2016 MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 SUPERFAMILY SSF52096 28 109 8.95E-71 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 SUPERFAMILY SSF52096 181 344 8.95E-71 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS09065 2f68ea823efaa1374886ccf62763733e 541 Pfam PF03572 Peptidase family S41 187 342 1.3E-48 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 Pfam PF00925 GTP cyclohydrolase II 216 376 7.7E-36 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 SUPERFAMILY SSF142695 211 377 1.19E-44 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 7 210 38.285 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 13 205 2.6E-86 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 PANTHER PTHR21327 4 376 8.0E-151 T 22-04-2016 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 SUPERFAMILY SSF55821 10 212 2.04E-86 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 Gene3D G3DSA:3.90.870.10 6 216 1.3E-99 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 9 206 1.9E-78 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 PIRSF PIRSF001259 7 378 1.4E-123 T 22-04-2016 MED134_RS04195 a923c2d5c334792970ddee15ccbf75b9 378 PANTHER PTHR21327:SF6 4 376 8.0E-151 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 PANTHER PTHR22550:SF8 1 329 2.9E-80 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 PRINTS PR00453 Von Willebrand factor type A domain signature 194 202 3.7E-5 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 PRINTS PR00453 Von Willebrand factor type A domain signature 92 109 3.7E-5 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 PRINTS PR00453 Von Willebrand factor type A domain signature 132 146 3.7E-5 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 SUPERFAMILY SSF53300 90 271 1.38E-40 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 Gene3D G3DSA:3.40.50.410 89 290 9.1E-35 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 SMART SM00327 91 265 1.4E-25 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 PANTHER PTHR22550 1 329 2.9E-80 T 22-04-2016 MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 Pfam PF00092 von Willebrand factor type A domain 93 286 1.6E-35 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09945 9c7fc1a17de142512463b2e90b5bfc00 334 Pfam PF07584 Aerotolerance regulator N-terminal 5 77 2.2E-16 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 Gene3D G3DSA:3.20.20.80 163 506 3.1E-112 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 32 161 6.3E-17 T 22-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 SUPERFAMILY SSF55545 28 164 8.9E-20 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PANTHER PTHR22600:SF21 28 503 4.0E-157 T 22-04-2016 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 165 477 2.7E-92 T 22-04-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PANTHER PTHR22600 28 503 4.0E-157 T 22-04-2016 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 SUPERFAMILY SSF51445 165 506 1.72E-113 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PIRSF PIRSF001093 3 515 1.3E-78 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 295 313 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 459 476 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 441 457 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 118 138 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 247 264 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 188 209 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 159 176 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 PRINTS PR00738 Glycosyl hydrolase family 20 signature 317 330 4.1E-49 T 22-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 MED134_RS03505 f93f85b14a280d55d7ee87cc53991821 516 Gene3D G3DSA:3.30.379.10 4 162 7.7E-23 T 22-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 5 173 2.0E-45 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PANTHER PTHR11910 7 178 4.6E-46 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 136 155 - T 22-04-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 5 173 1.2E-37 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PRINTS PR00125 ATP synthase delta subunit signature 149 167 1.5E-18 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PRINTS PR00125 ATP synthase delta subunit signature 134 149 1.5E-18 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PRINTS PR00125 ATP synthase delta subunit signature 83 97 1.5E-18 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PRINTS PR00125 ATP synthase delta subunit signature 72 83 1.5E-18 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 PRINTS PR00125 ATP synthase delta subunit signature 4 23 1.5E-18 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 Gene3D G3DSA:1.10.520.20 5 103 2.3E-19 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 176 16.415 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 MED134_RS09415 24fbaa54c3bfb2c8015d320e08f568cb 178 SUPERFAMILY SSF47928 5 103 2.09E-20 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 407 3.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 132 1.9E-19 T 22-04-2016 IPR000014 PAS domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SMART SM00388 185 253 1.7E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SUPERFAMILY SSF55874 242 406 4.71E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Pfam PF13426 PAS domain 21 124 2.4E-10 T 22-04-2016 IPR000014 PAS domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 349 1.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 363 1.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 386 1.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 405 1.2E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SMART SM00387 298 408 1.0E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Gene3D G3DSA:1.10.287.130 176 238 5.6E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Gene3D G3DSA:3.30.565.10 239 407 1.0E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SUPERFAMILY SSF55785 21 133 2.27E-20 T 22-04-2016 IPR000014 PAS domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Gene3D G3DSA:3.30.450.20 10 124 1.3E-17 T 22-04-2016 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PANTHER PTHR24423 183 405 3.1E-68 T 22-04-2016 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 PANTHER PTHR24423 4 143 3.1E-68 T 22-04-2016 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 186 253 1.8E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SMART SM00091 10 76 5.6E-6 T 22-04-2016 IPR000014 PAS domain MED134_RS04655 e7367f6c2d4368131fbbb64a78102ef4 409 SUPERFAMILY SSF47384 173 254 1.86E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 187 203 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 PANTHER PTHR11075 1 315 6.4E-129 T 22-04-2016 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 Pfam PF00472 RF-1 domain 171 280 1.9E-35 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 Gene3D G3DSA:1.20.58.410 1 58 1.2E-5 T 22-04-2016 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 Gene3D G3DSA:3.30.160.20 170 247 1.5E-30 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 Pfam PF03462 PCRF domain 2 162 2.8E-50 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 SMART SM00937 29 137 1.7E-38 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 PANTHER PTHR11075:SF6 1 315 6.4E-129 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 6 305 1.5E-120 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MED134_RS04125 7680576cc69572716ed8a7e0a1010901 316 SUPERFAMILY SSF75620 2 310 2.22E-113 T 22-04-2016 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 Pfam PF03462 PCRF domain 9 203 4.5E-66 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 Gene3D G3DSA:1.20.58.410 4 92 7.1E-16 T 22-04-2016 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 Gene3D G3DSA:3.30.160.20 210 288 1.9E-33 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 Pfam PF00472 RF-1 domain 212 320 5.7E-41 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 SUPERFAMILY SSF75620 8 352 1.57E-125 T 22-04-2016 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 353 1.4E-146 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 PANTHER PTHR11075 1 355 5.5E-162 T 22-04-2016 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 37.298 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 SMART SM00937 62 178 2.8E-53 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 MED134_RS03760 f33236a5599841ad6d156ba57fa4c6f0 359 PANTHER PTHR11075:SF9 1 355 5.5E-162 T 22-04-2016 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 SUPERFAMILY SSF63411 40 249 1.43E-53 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Pfam PF05193 Peptidase M16 inactive domain 210 386 5.9E-30 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Pfam PF05193 Peptidase M16 inactive domain 681 857 3.0E-18 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Gene3D G3DSA:3.30.830.10 517 732 3.1E-42 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 PANTHER PTHR11851:SF136 38 905 4.1E-164 T 22-04-2016 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 SUPERFAMILY SSF63411 734 946 7.49E-42 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Gene3D G3DSA:3.30.830.10 40 265 1.3E-51 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 PANTHER PTHR11851 38 905 4.1E-164 T 22-04-2016 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 SUPERFAMILY SSF63411 510 712 3.0E-41 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 SUPERFAMILY SSF63411 270 458 7.17E-33 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Gene3D G3DSA:3.30.830.10 740 925 4.0E-23 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Gene3D G3DSA:3.30.830.10 275 447 2.2E-18 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Pfam PF00675 Insulinase (Peptidase family M16) 52 139 3.9E-15 T 22-04-2016 IPR011765 Peptidase M16, N-terminal MED134_RS06265 5186d86e8e3fa3343e8a3485d2ef25c8 953 Pfam PF00675 Insulinase (Peptidase family M16) 537 655 5.1E-9 T 22-04-2016 IPR011765 Peptidase M16, N-terminal MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 386 403 1.3E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 403 422 1.3E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 Gene3D G3DSA:1.10.8.60 185 260 3.2E-21 T 22-04-2016 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 Pfam PF00158 Sigma-54 interaction domain 13 179 5.3E-65 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 Pfam PF02954 Bacterial regulatory protein, Fis family 384 420 1.4E-11 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PANTHER PTHR32071 337 422 6.1E-146 T 22-04-2016 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PANTHER PTHR32071 8 264 6.1E-146 T 22-04-2016 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 Gene3D G3DSA:1.10.10.60 376 419 2.3E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 99 114 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 37 50 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 SMART SM00382 33 176 8.1E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 Gene3D G3DSA:3.40.50.300 13 184 7.5E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PANTHER PTHR32071:SF23 337 422 6.1E-146 T 22-04-2016 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 PANTHER PTHR32071:SF23 8 264 6.1E-146 T 22-04-2016 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 SUPERFAMILY SSF46689 369 422 5.68E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS06130 9278f750e9442d4c938e6d8662c9cb5a 422 SUPERFAMILY SSF52540 12 256 1.73E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07820 1f38a2cb43611a770b2384bc17e8b808 590 SMART SM00534 415 587 8.4E-12 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07820 1f38a2cb43611a770b2384bc17e8b808 590 SUPERFAMILY SSF52540 388 588 2.1E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07820 1f38a2cb43611a770b2384bc17e8b808 590 Gene3D G3DSA:3.40.50.300 379 588 3.1E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07820 1f38a2cb43611a770b2384bc17e8b808 590 Pfam PF00488 MutS domain V 419 576 1.1E-26 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS07820 1f38a2cb43611a770b2384bc17e8b808 590 PANTHER PTHR11361 332 588 1.5E-48 T 22-04-2016 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 Gene3D G3DSA:1.25.40.10 107 404 1.3E-34 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 PANTHER PTHR23083 364 404 1.9E-23 T 22-04-2016 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 PANTHER PTHR23083 122 180 1.9E-23 T 22-04-2016 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 PANTHER PTHR23083 225 334 1.9E-23 T 22-04-2016 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SUPERFAMILY SSF48452 77 167 1.5E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 Pfam PF13181 Tetratricopeptide repeat 256 287 0.013 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SUPERFAMILY SSF48452 229 405 1.04E-25 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 Pfam PF13414 TPR repeat 300 334 2.0E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SMART SM00028 220 253 90.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SMART SM00028 288 321 3.3E-7 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SMART SM00028 351 384 450.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS01965 9656902dbd0e082ddd7139976f90b35d 415 SMART SM00028 254 287 14.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 PANTHER PTHR30069 4 568 3.7E-54 T 22-04-2016 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 PANTHER PTHR30069:SF2 4 568 3.7E-54 T 22-04-2016 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 Pfam PF07715 TonB-dependent Receptor Plug Domain 115 219 2.6E-23 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 Gene3D G3DSA:2.170.130.10 97 223 3.2E-33 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 Gene3D G3DSA:2.60.40.1120 21 96 1.5E-15 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 Gene3D G3DSA:2.40.170.20 224 750 1.3E-56 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 SUPERFAMILY SSF49464 21 111 2.31E-15 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 SUPERFAMILY SSF56935 101 693 4.03E-84 T 22-04-2016 MED134_RS10255 eddd15bd3b388e1aeda8f6a9aab294e4 752 Pfam PF13715 CarboxypepD_reg-like domain 22 105 8.8E-22 T 22-04-2016 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 12 411 5.5E-83 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 SUPERFAMILY SSF69742 9 160 2.88E-37 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 Gene3D G3DSA:3.40.50.720 165 302 1.1E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 13 158 2.1E-33 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 317 411 7.0E-20 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 179 302 7.5E-25 T 22-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 SUPERFAMILY SSF51735 163 308 6.73E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 PANTHER PTHR13812:SF18 3 413 3.5E-67 T 22-04-2016 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 PIRSF PIRSF000445 8 416 3.0E-104 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 PANTHER PTHR13812 3 413 3.5E-67 T 22-04-2016 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 SUPERFAMILY SSF69075 315 412 4.97E-12 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 22-04-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS08665 e769c83bec271fe9dee31addc2b08e96 416 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 9 409 22.629 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS00085 dcc9657c317ce54a2d76c784e3e78a2d 199 PANTHER PTHR31573:SF1 13 198 4.5E-74 T 22-04-2016 MED134_RS00085 dcc9657c317ce54a2d76c784e3e78a2d 199 PANTHER PTHR31573 13 198 4.5E-74 T 22-04-2016 IPR032852 DNA oxidative demethylase ALKBH2 GO:0006281 MED134_RS00085 dcc9657c317ce54a2d76c784e3e78a2d 199 Gene3D G3DSA:2.60.120.590 18 198 3.6E-40 T 22-04-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MED134_RS00085 dcc9657c317ce54a2d76c784e3e78a2d 199 SUPERFAMILY SSF51197 4 198 5.36E-65 T 22-04-2016 MED134_RS00085 dcc9657c317ce54a2d76c784e3e78a2d 199 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 18 196 5.3E-35 T 22-04-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MED134_RS04915 d539749b55b61a9a8b64d98d3ce450b0 67 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 60 1.1E-9 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MED134_RS04915 d539749b55b61a9a8b64d98d3ce450b0 67 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 58 5.6E-14 T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 MED134_RS04915 d539749b55b61a9a8b64d98d3ce450b0 67 Gene3D G3DSA:1.20.5.1030 2 58 1.5E-14 T 22-04-2016 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 PANTHER PTHR18964 1 65 1.8E-55 T 22-04-2016 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 PANTHER PTHR18964 82 262 1.8E-55 T 22-04-2016 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 Pfam PF01238 Phosphomannose isomerase type I 10 116 1.4E-11 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 SUPERFAMILY SSF51182 1 314 1.67E-85 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 Gene3D G3DSA:2.60.120.10 236 320 1.4E-14 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 PANTHER PTHR18964:SF114 1 65 1.8E-55 T 22-04-2016 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 PANTHER PTHR18964:SF114 82 262 1.8E-55 T 22-04-2016 MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 Gene3D G3DSA:2.60.120.10 2 224 9.1E-72 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS11130 e7501c307647859f3cec7e51c0cd9749 323 PIRSF PIRSF036894 3 322 3.2E-96 T 22-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 Gene3D G3DSA:2.40.50.140 1 63 7.4E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 Pfam PF00313 'Cold-shock' DNA-binding domain 3 62 4.3E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 SMART SM00357 3 63 7.7E-15 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 SUPERFAMILY SSF50249 1 63 4.93E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 PRINTS PR00050 Cold shock protein signature 36 54 1.0E-9 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 PRINTS PR00050 Cold shock protein signature 4 19 1.0E-9 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01245 7e62cb54fb78a0ef69aeb2c15cf36a62 64 PIRSF PIRSF002599 1 64 4.3E-15 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 MED134_RS11385 be187df1d6085c16ed1f1a91e139a46c 419 Pfam PF12704 MacB-like periplasmic core domain 21 248 2.5E-23 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS11385 be187df1d6085c16ed1f1a91e139a46c 419 PANTHER PTHR30572 1 419 9.9E-61 T 22-04-2016 MED134_RS11385 be187df1d6085c16ed1f1a91e139a46c 419 Pfam PF02687 FtsX-like permease family 291 412 1.1E-19 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 SUPERFAMILY SSF103481 207 288 3.92E-9 T 22-04-2016 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 Pfam PF00892 EamA-like transporter family 150 286 6.5E-15 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 Pfam PF00892 EamA-like transporter family 8 135 5.1E-22 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 PANTHER PTHR12715:SF17 8 291 2.7E-35 T 22-04-2016 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 SUPERFAMILY SSF103481 43 138 3.14E-12 T 22-04-2016 MED134_RS10195 4bf6e124389ecdc3ae62ef8730e69165 294 PANTHER PTHR12715 8 291 2.7E-35 T 22-04-2016 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 Gene3D G3DSA:1.20.1250.20 363 518 3.9E-7 T 22-04-2016 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 SUPERFAMILY SSF103473 17 232 1.13E-29 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 SUPERFAMILY SSF103473 306 519 1.13E-29 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 Pfam PF00854 POT family 357 483 7.1E-17 T 22-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 Pfam PF00854 POT family 93 215 8.2E-30 T 22-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 PANTHER PTHR11654 358 529 9.8E-134 T 22-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 PANTHER PTHR11654 8 291 9.8E-134 T 22-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 Gene3D G3DSA:1.20.1250.20 23 205 8.1E-16 T 22-04-2016 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 12 219 5.4E-60 T 22-04-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 PANTHER PTHR11654:SF119 358 529 9.8E-134 T 22-04-2016 MED134_RS06460 b5383a536a46b967fffd0db040abc879 529 PANTHER PTHR11654:SF119 8 291 9.8E-134 T 22-04-2016 MED134_RS10610 363944c030cc6f026570625670499b79 764 Gene3D G3DSA:2.60.420.10 693 761 1.1E-23 T 22-04-2016 MED134_RS10610 363944c030cc6f026570625670499b79 764 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 15 268 2.4E-61 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MED134_RS10610 363944c030cc6f026570625670499b79 764 Gene3D G3DSA:1.50.10.10 320 692 8.3E-140 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 MED134_RS10610 363944c030cc6f026570625670499b79 764 PIRSF PIRSF036289 1 762 2.1E-251 T 22-04-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase MED134_RS10610 363944c030cc6f026570625670499b79 764 SUPERFAMILY SSF48208 276 758 6.29E-138 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 MED134_RS10610 363944c030cc6f026570625670499b79 764 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 713 758 1.4E-12 T 22-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal MED134_RS10610 363944c030cc6f026570625670499b79 764 Gene3D G3DSA:2.70.98.40 5 271 5.4E-76 T 22-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MED134_RS10610 363944c030cc6f026570625670499b79 764 SUPERFAMILY SSF74650 6 270 1.6E-67 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MED134_RS10610 363944c030cc6f026570625670499b79 764 PANTHER PTHR11051 9 754 4.0E-267 T 22-04-2016 MED134_RS10610 363944c030cc6f026570625670499b79 764 PANTHER PTHR11051:SF11 9 754 4.0E-267 T 22-04-2016 MED134_RS10610 363944c030cc6f026570625670499b79 764 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 325 707 6.0E-140 T 22-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 ProSitePatterns PS00893 Nudix box signature. 97 118 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 SUPERFAMILY SSF55811 61 186 1.18E-24 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 Pfam PF00293 NUDIX domain 73 184 3.3E-20 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 PANTHER PTHR22769 73 181 4.3E-12 T 22-04-2016 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 Gene3D G3DSA:3.90.79.10 65 193 1.2E-24 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 PRINTS PR00502 NUDIX hydrolase family signature 92 106 1.1E-5 T 22-04-2016 IPR020476 NUDIX hydrolase MED134_RS12955 e50bc3639fe4ee4abd5157e658592d90 207 PRINTS PR00502 NUDIX hydrolase family signature 106 121 1.1E-5 T 22-04-2016 IPR020476 NUDIX hydrolase MED134_RS00410 9c0c6ecde60ac3e369ebb22ebbbbea52 244 Gene3D G3DSA:3.90.1680.10 1 222 2.1E-43 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS00410 9c0c6ecde60ac3e369ebb22ebbbbea52 244 PANTHER PTHR13604 51 221 6.5E-35 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS00410 9c0c6ecde60ac3e369ebb22ebbbbea52 244 Pfam PF02586 SOS response associated peptidase (SRAP) 1 217 3.6E-40 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS00410 9c0c6ecde60ac3e369ebb22ebbbbea52 244 SUPERFAMILY SSF143081 2 221 6.93E-44 T 22-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 PANTHER PTHR15238:SF3 1 60 4.3E-24 T 22-04-2016 MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 PANTHER PTHR15238 1 60 4.3E-24 T 22-04-2016 MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 60 15.015 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 SUPERFAMILY SSF57829 3 60 1.16E-15 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 60 5.6E-18 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05070 c658c22164c0499fd00942d5b1ca3d91 60 Pfam PF00471 Ribosomal protein L33 8 60 4.2E-20 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 11 272 42.669 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 PIRSF PIRSF000388 1 272 3.3E-111 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 Gene3D G3DSA:3.20.20.60 9 272 5.1E-117 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 14 272 4.7E-99 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 PANTHER PTHR20881 8 272 3.4E-143 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 SUPERFAMILY SSF51621 10 272 1.45E-104 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS11825 97478d123902c2c9afaf6c786e4c42a8 272 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 267 4.6E-115 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 MED134_RS07900 4d5be976baf97c79e36f1abb4bd3b344 126 SMART SM00448 3 115 4.1E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07900 4d5be976baf97c79e36f1abb4bd3b344 126 Pfam PF00072 Response regulator receiver domain 6 89 2.4E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07900 4d5be976baf97c79e36f1abb4bd3b344 126 SUPERFAMILY SSF52172 3 88 4.41E-18 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07900 4d5be976baf97c79e36f1abb4bd3b344 126 Gene3D G3DSA:3.40.50.2300 3 123 1.4E-19 T 22-04-2016 MED134_RS07900 4d5be976baf97c79e36f1abb4bd3b344 126 PANTHER PTHR26402 3 84 3.4E-16 T 22-04-2016 MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 PANTHER PTHR31801:SF3 2 264 7.6E-104 T 22-04-2016 MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 SUPERFAMILY SSF51219 6 245 3.66E-81 T 22-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 Gene3D G3DSA:3.60.160.10 1 249 6.2E-98 T 22-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 PANTHER PTHR31801 2 264 7.6E-104 T 22-04-2016 MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 2.3E-66 T 22-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 MED134_RS00185 369fb3d6ada7ba0a09f9742fa7325086 266 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 233 1.1E-29 T 22-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 MED134_RS01755 79b8dfcb7d2a5d14c3f1efe76bb2f58c 169 Pfam PF02517 CAAX protease self-immunity 63 158 5.2E-9 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 MED134_RS07625 852481655b95e1301e8832abf200ad6c 221 Pfam PF00072 Response regulator receiver domain 5 129 1.3E-5 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07625 852481655b95e1301e8832abf200ad6c 221 Gene3D G3DSA:1.10.10.10 135 220 3.1E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS07625 852481655b95e1301e8832abf200ad6c 221 Gene3D G3DSA:3.40.50.2300 4 134 4.2E-14 T 22-04-2016 MED134_RS07625 852481655b95e1301e8832abf200ad6c 221 SUPERFAMILY SSF52172 3 145 1.38E-8 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 PANTHER PTHR14413 1 119 4.2E-55 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 Pfam PF01196 Ribosomal protein L17 20 116 2.0E-32 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 4.2E-41 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 Gene3D G3DSA:3.90.1030.10 1 117 5.0E-47 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 PANTHER PTHR14413:SF5 1 119 4.2E-55 T 22-04-2016 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 SUPERFAMILY SSF64263 1 119 5.62E-46 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12365 ec4ef3abb8530258f0927144980b537f 155 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.397 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12595 b418913b8abb0182e52b0b37cdd5b338 114 Gene3D G3DSA:3.40.250.10 11 114 3.7E-28 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12595 b418913b8abb0182e52b0b37cdd5b338 114 Pfam PF00581 Rhodanese-like domain 24 114 1.3E-18 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12595 b418913b8abb0182e52b0b37cdd5b338 114 SMART SM00450 21 114 4.8E-20 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12595 b418913b8abb0182e52b0b37cdd5b338 114 PANTHER PTHR12231 36 113 4.8E-13 T 22-04-2016 MED134_RS12595 b418913b8abb0182e52b0b37cdd5b338 114 SUPERFAMILY SSF52821 6 113 1.7E-28 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS00320 d8d32d0bf4dd8ca90b6fdadedf23c178 448 PANTHER PTHR38733 1 448 3.3E-42 T 22-04-2016 MED134_RS00320 d8d32d0bf4dd8ca90b6fdadedf23c178 448 PANTHER PTHR38733:SF1 1 448 3.3E-42 T 22-04-2016 MED134_RS00320 d8d32d0bf4dd8ca90b6fdadedf23c178 448 Pfam PF10117 McrBC 5-methylcytosine restriction system component 64 385 8.4E-67 T 22-04-2016 IPR019292 5-methylcytosine restriction system component MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 108 1.8E-19 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 SUPERFAMILY SSF89919 1 112 1.05E-28 T 22-04-2016 IPR023799 Ribosome-binding factor A domain MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 12 98 5.0E-17 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 Gene3D G3DSA:3.30.300.20 1 103 3.9E-26 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 Pfam PF02033 Ribosome-binding factor A 5 109 2.4E-23 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 PANTHER PTHR33515 1 109 4.5E-24 T 22-04-2016 MED134_RS06725 de2411d82ec4b197f1e95afb15574e34 130 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 16.715 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 MED134_RS03990 69432d1e1582161f15e15eedad69bb5e 180 Pfam PF13302 Acetyltransferase (GNAT) domain 8 149 7.4E-21 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS03990 69432d1e1582161f15e15eedad69bb5e 180 PANTHER PTHR13256 2 160 3.4E-26 T 22-04-2016 MED134_RS03990 69432d1e1582161f15e15eedad69bb5e 180 SUPERFAMILY SSF55729 1 161 1.53E-32 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS03990 69432d1e1582161f15e15eedad69bb5e 180 Gene3D G3DSA:3.40.630.30 2 159 3.0E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 290 309 3.6E-12 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 349 368 3.6E-12 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 197 220 3.6E-12 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 PRINTS PR00447 Natural resistance-associated macrophage protein signature 148 169 3.6E-12 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 PANTHER PTHR11706 10 396 3.3E-41 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS04770 600befbc7d2d00bd419464b7c94fb25b 408 Pfam PF01566 Natural resistance-associated macrophage protein 31 379 6.3E-87 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 PANTHER PTHR11019:SF1 24 85 4.3E-23 T 22-04-2016 MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 PANTHER PTHR11019:SF1 102 182 4.3E-23 T 22-04-2016 MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 Gene3D G3DSA:3.40.50.880 24 250 7.2E-51 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 Pfam PF01965 DJ-1/PfpI family 43 183 2.0E-12 T 22-04-2016 IPR002818 DJ-1/PfpI MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 SUPERFAMILY SSF52317 26 250 2.63E-42 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 PANTHER PTHR11019 24 85 4.3E-23 T 22-04-2016 MED134_RS03705 934e940c95a15726db8c16f8a8234937 253 PANTHER PTHR11019 102 182 4.3E-23 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 13 916 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 PANTHER PTHR32282 11 931 0.0 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 SUPERFAMILY SSF52540 608 903 3.22E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Pfam PF00005 ABC transporter 735 851 1.8E-5 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 ProSitePatterns PS00211 ABC transporters family signature. 820 834 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.30.1490.20 141 163 4.9E-12 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.30.1490.20 211 261 4.9E-12 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:1.20.1580.10 682 810 6.4E-47 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 PANTHER PTHR32282:SF2 11 931 0.0 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.40.50.300 811 930 1.6E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.40.50.300 469 582 1.1E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.40.50.300 13 61 1.1E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.40.50.300 679 680 1.6E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:3.40.50.300 596 638 1.6E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:1.10.8.280 297 397 5.8E-17 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 SUPERFAMILY SSF52540 17 214 8.32E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 SUPERFAMILY SSF52540 421 560 8.32E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:1.20.1580.10 398 468 2.1E-49 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:1.20.1580.10 102 139 2.1E-49 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Gene3D G3DSA:1.20.1580.10 262 294 2.1E-49 T 22-04-2016 MED134_RS02075 9d57acb42f12bb34589abe3732cbd8b0 931 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 442 538 2.0E-6 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS09250 30f1a8c76eafc0d6e5f2e05b26629997 206 SUPERFAMILY SSF53335 52 154 2.15E-8 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09250 30f1a8c76eafc0d6e5f2e05b26629997 206 Pfam PF13578 Methyltransferase domain 49 153 2.3E-7 T 22-04-2016 MED134_RS09250 30f1a8c76eafc0d6e5f2e05b26629997 206 Gene3D G3DSA:3.40.50.150 23 155 2.4E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 3.3E-98 T 22-04-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 SUPERFAMILY SSF100950 6 217 1.41E-71 T 22-04-2016 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 Gene3D G3DSA:3.40.810.20 5 213 8.1E-87 T 22-04-2016 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 PANTHER PTHR13707 2 217 2.3E-117 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 Pfam PF01144 Coenzyme A transferase 6 201 1.9E-40 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 22-04-2016 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 MED134_RS08770 b690bb38baa0366357e08904d220a00c 218 SMART SM00882 6 202 1.3E-72 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 Pfam PF01551 Peptidase family M23 137 172 1.6E-6 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 Pfam PF01551 Peptidase family M23 51 114 1.7E-10 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 Gene3D G3DSA:2.70.70.10 20 175 2.2E-32 T 22-04-2016 MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 SUPERFAMILY SSF51261 35 174 2.46E-26 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 PANTHER PTHR21666 1 114 9.7E-25 T 22-04-2016 MED134_RS13910 4d462f7421b8e13f5a0ffba6aca489dd 569 PANTHER PTHR21666 138 175 9.7E-25 T 22-04-2016 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 SUPERFAMILY SSF116734 13 219 6.21E-38 T 22-04-2016 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 SUPERFAMILY SSF116734 222 443 1.96E-40 T 22-04-2016 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 PANTHER PTHR30408:SF6 15 247 1.5E-47 T 22-04-2016 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 Pfam PF01420 Type I restriction modification DNA specificity domain 236 416 3.7E-12 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 Pfam PF01420 Type I restriction modification DNA specificity domain 97 202 2.5E-6 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MED134_RS00515 f3ac1b8dd4bb36d0358e2e7c5fc3efed 444 PANTHER PTHR30408 15 247 1.5E-47 T 22-04-2016 MED134_RS07280 c50601a5bd33418213cfd42845d5122d 153 PANTHER PTHR23241 22 148 1.5E-15 T 22-04-2016 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 Gene3D G3DSA:3.40.50.200 145 514 3.0E-51 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 231 241 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 Pfam PF00082 Subtilase family 226 505 1.8E-25 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 245 3.1E-12 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 456 472 3.1E-12 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 282 295 3.1E-12 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 SUPERFAMILY SSF52743 208 514 8.77E-50 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PANTHER PTHR10795:SF419 209 514 7.6E-26 T 22-04-2016 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PANTHER PTHR10795:SF419 115 169 7.6E-26 T 22-04-2016 MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PANTHER PTHR10795 209 514 7.6E-26 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS12695 3cb82d85d3faa1b57997ba1780613b86 514 PANTHER PTHR10795 115 169 7.6E-26 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS03180 3344bed44920d22e39d22fbbbfc7c31e 263 PANTHER PTHR15032:SF13 32 246 1.5E-25 T 22-04-2016 MED134_RS03180 3344bed44920d22e39d22fbbbfc7c31e 263 PANTHER PTHR15032 32 246 1.5E-25 T 22-04-2016 MED134_RS03180 3344bed44920d22e39d22fbbbfc7c31e 263 Pfam PF13483 Beta-lactamase superfamily domain 50 227 5.6E-20 T 22-04-2016 MED134_RS03180 3344bed44920d22e39d22fbbbfc7c31e 263 SUPERFAMILY SSF56281 44 250 6.53E-22 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS03180 3344bed44920d22e39d22fbbbfc7c31e 263 Gene3D G3DSA:3.60.15.10 36 246 3.9E-36 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Gene3D G3DSA:3.40.1190.10 92 306 5.1E-59 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Gene3D G3DSA:3.90.190.20 308 442 1.4E-46 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 SUPERFAMILY SSF51984 3 92 1.44E-13 T 22-04-2016 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 3 445 32.644 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 5 443 5.9E-121 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 PANTHER PTHR23135:SF2 3 445 1.7E-143 T 22-04-2016 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 SUPERFAMILY SSF53244 306 445 5.04E-45 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Gene3D G3DSA:3.40.50.720 2 90 3.3E-11 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Pfam PF08245 Mur ligase middle domain 108 287 2.5E-30 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 PANTHER PTHR23135 3 445 1.7E-143 T 22-04-2016 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 375 2.9E-7 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12520 6e645ba21ed2402fa1761f78a1d728a0 445 SUPERFAMILY SSF53623 94 304 1.44E-50 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 Pfam PF02630 SCO1/SenC 60 201 5.3E-19 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 Gene3D G3DSA:3.40.30.10 15 22 1.3E-45 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 Gene3D G3DSA:3.40.30.10 56 223 1.3E-45 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 PANTHER PTHR12151:SF10 64 222 9.4E-30 T 22-04-2016 MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 SUPERFAMILY SSF52833 61 223 1.19E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10305 2d37c97b26fc101e83528ac58741684c 234 PANTHER PTHR12151 64 222 9.4E-30 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 4.5E-75 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 1.7E-26 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 Pfam PF01479 S4 domain 94 140 8.3E-20 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 SMART SM00363 93 157 1.0E-18 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 SUPERFAMILY SSF55174 3 201 4.97E-64 T 22-04-2016 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 PANTHER PTHR11831:SF4 1 201 2.1E-77 T 22-04-2016 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 PANTHER PTHR11831 1 201 2.1E-77 T 22-04-2016 IPR022801 Ribosomal protein S4/S9 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 Gene3D G3DSA:3.10.290.10 100 183 1.6E-31 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 Gene3D G3DSA:1.10.1050.10 1 99 3.1E-41 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 33.503 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MED134_RS12355 8cd575d0ca1746b5b3dd1c0fbb259326 201 SMART SM01390 3 92 4.0E-45 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 SUPERFAMILY SSF53383 11 470 1.36E-106 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 73 408 5.4E-55 T 22-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 PANTHER PTHR11999 69 467 3.7E-80 T 22-04-2016 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 15 34 9.0E-10 T 22-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 138 158 9.0E-10 T 22-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 389 408 9.0E-10 T 22-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 Gene3D G3DSA:3.40.640.10 90 359 7.9E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS08215 a174c7bf7dee69b60e25b45ee996e0af 474 Gene3D G3DSA:3.90.1150.10 360 471 4.1E-30 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 PANTHER PTHR11749 2 218 3.4E-110 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 PIRSF PIRSF001461 1 219 7.5E-88 T 22-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 202 1.2E-79 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 215 1.5E-86 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 SUPERFAMILY SSF51366 5 216 2.06E-73 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 Gene3D G3DSA:3.20.20.70 2 217 2.2E-89 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS12675 ecc593841d0965f67c611ac66e11f343 219 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MED134_RS04210 1d5728ec2ec7ae6cf0c1a36d1db6ec1e 517 SUPERFAMILY SSF51126 279 511 3.37E-6 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor MED134_RS04210 1d5728ec2ec7ae6cf0c1a36d1db6ec1e 517 SUPERFAMILY SSF51126 185 251 3.37E-6 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 Gene3D G3DSA:3.40.1190.20 1 297 4.5E-58 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 233 246 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 Pfam PF00294 pfkB family carbohydrate kinase 1 281 1.7E-32 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 PANTHER PTHR10584:SF179 1 310 8.7E-60 T 22-04-2016 MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 SUPERFAMILY SSF53613 1 291 9.98E-64 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS08970 fa7f992457e5891bb7a0cfaa57a93d2f 310 PANTHER PTHR10584 1 310 8.7E-60 T 22-04-2016 MED134_RS08575 453ff1fd1002939c802af9314885a87a 381 SUPERFAMILY SSF51905 3 238 1.22E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08575 453ff1fd1002939c802af9314885a87a 381 Gene3D G3DSA:3.50.50.60 93 168 2.5E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08575 453ff1fd1002939c802af9314885a87a 381 Gene3D G3DSA:3.50.50.60 4 60 2.5E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08575 453ff1fd1002939c802af9314885a87a 381 Gene3D G3DSA:3.50.50.60 247 274 2.5E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS08575 453ff1fd1002939c802af9314885a87a 381 Pfam PF05834 Lycopene cyclase protein 6 375 2.6E-58 T 22-04-2016 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 Pfam PF01238 Phosphomannose isomerase type I 8 115 4.1E-15 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 PANTHER PTHR18964:SF114 9 65 3.8E-58 T 22-04-2016 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 PANTHER PTHR18964:SF114 82 260 3.8E-58 T 22-04-2016 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 Gene3D G3DSA:2.60.120.10 2 222 2.3E-73 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 Gene3D G3DSA:2.60.120.10 234 320 1.9E-16 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 SUPERFAMILY SSF51182 2 310 6.05E-83 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 PANTHER PTHR18964 9 65 3.8E-58 T 22-04-2016 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 PANTHER PTHR18964 82 260 3.8E-58 T 22-04-2016 MED134_RS00685 562ec9cbc52b765c76dee106012237f4 322 PIRSF PIRSF036894 3 320 4.7E-99 T 22-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MED134_RS05405 3a27f964b38d6dc9f926fb6b48f8b153 294 PANTHER PTHR22936 19 212 2.7E-16 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 MED134_RS05405 3a27f964b38d6dc9f926fb6b48f8b153 294 SUPERFAMILY SSF144091 10 204 3.92E-31 T 22-04-2016 MED134_RS05405 3a27f964b38d6dc9f926fb6b48f8b153 294 Pfam PF01694 Rhomboid family 59 202 1.6E-21 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS05405 3a27f964b38d6dc9f926fb6b48f8b153 294 Gene3D G3DSA:1.20.1540.10 13 201 4.9E-27 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS00105 dac7567f324d13f6cf69078df49b25c0 242 Pfam PF02230 Phospholipase/Carboxylesterase 46 232 3.9E-12 T 22-04-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MED134_RS00105 dac7567f324d13f6cf69078df49b25c0 242 Gene3D G3DSA:3.40.50.1820 14 241 5.0E-39 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00105 dac7567f324d13f6cf69078df49b25c0 242 SUPERFAMILY SSF53474 20 240 3.37E-33 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00105 dac7567f324d13f6cf69078df49b25c0 242 PANTHER PTHR10655 20 234 1.3E-49 T 22-04-2016 MED134_RS00105 dac7567f324d13f6cf69078df49b25c0 242 PANTHER PTHR10655:SF24 20 234 1.3E-49 T 22-04-2016 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 Pfam PF13715 CarboxypepD_reg-like domain 23 99 1.4E-8 T 22-04-2016 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 SUPERFAMILY SSF56935 841 925 3.63E-47 T 22-04-2016 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 SUPERFAMILY SSF56935 143 398 3.63E-47 T 22-04-2016 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 SUPERFAMILY SSF56935 432 811 3.63E-47 T 22-04-2016 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 Gene3D G3DSA:2.40.170.20 214 381 1.2E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 Gene3D G3DSA:2.40.170.20 434 925 1.2E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 Gene3D G3DSA:2.60.40.1120 22 97 1.1E-7 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07705 c1dd70152cfaa9a5cfad47d0a1f16f07 925 SUPERFAMILY SSF49464 22 97 2.75E-9 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS03030 4412945925746679687fa01f10e2f82f 318 Gene3D G3DSA:3.30.70.890 180 305 2.4E-31 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PANTHER PTHR20861 1 304 1.0E-77 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 Hamap MF_00384 Homoserine kinase [thrB]. 16 317 27.478 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 Pfam PF00288 GHMP kinases N terminal domain 93 159 5.7E-13 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 SUPERFAMILY SSF55060 184 280 3.35E-22 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PANTHER PTHR20861:SF1 1 304 1.0E-77 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 TIGRFAM TIGR00191 thrB: homoserine kinase 16 287 5.3E-65 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PRINTS PR00958 Homoserine kinase signature 263 278 2.1E-25 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PRINTS PR00958 Homoserine kinase signature 184 201 2.1E-25 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PRINTS PR00958 Homoserine kinase signature 106 121 2.1E-25 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PRINTS PR00958 Homoserine kinase signature 146 159 2.1E-25 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PRINTS PR00958 Homoserine kinase signature 23 38 2.1E-25 T 22-04-2016 MED134_RS03030 4412945925746679687fa01f10e2f82f 318 SUPERFAMILY SSF54211 16 167 2.66E-27 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS03030 4412945925746679687fa01f10e2f82f 318 Gene3D G3DSA:3.30.230.10 15 168 4.7E-41 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS03030 4412945925746679687fa01f10e2f82f 318 PIRSF PIRSF000676 12 318 4.5E-74 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 MED134_RS00795 0054eb12fa71498d65c509d39ae21069 442 SUPERFAMILY SSF103473 35 436 5.1E-29 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS00795 0054eb12fa71498d65c509d39ae21069 442 Pfam PF07690 Major Facilitator Superfamily 276 429 3.1E-14 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS00795 0054eb12fa71498d65c509d39ae21069 442 PANTHER PTHR23526 58 432 4.7E-17 T 22-04-2016 MED134_RS00795 0054eb12fa71498d65c509d39ae21069 442 Gene3D G3DSA:1.20.1250.20 62 226 2.3E-4 T 22-04-2016 MED134_RS00795 0054eb12fa71498d65c509d39ae21069 442 Gene3D G3DSA:1.20.1250.20 271 436 2.3E-14 T 22-04-2016 MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 SUPERFAMILY SSF54106 494 538 4.19E-10 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Gene3D G3DSA:1.10.530.10 178 328 2.8E-42 T 22-04-2016 MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Pfam PF01476 LysM domain 429 470 2.1E-13 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Pfam PF01476 LysM domain 496 539 5.2E-14 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 200 228 - T 22-04-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Pfam PF01464 Transglycosylase SLT domain 190 291 1.0E-23 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 SMART SM00257 428 471 4.0E-12 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 SMART SM00257 495 539 4.2E-13 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 SUPERFAMILY SSF54106 427 471 2.09E-11 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 PANTHER PTHR21666:SF206 138 540 6.9E-66 T 22-04-2016 MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Gene3D G3DSA:3.10.350.10 427 471 1.3E-18 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 Gene3D G3DSA:3.10.350.10 494 538 1.3E-17 T 22-04-2016 IPR018392 LysM domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 SUPERFAMILY SSF53955 163 318 2.53E-37 T 22-04-2016 IPR023346 Lysozyme-like domain MED134_RS09200 b49bff9d45deb2f07bda551f7320784e 540 PANTHER PTHR21666 138 540 6.9E-66 T 22-04-2016 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 203 12.527 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 178 194 1.1E-12 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 49 57 1.1E-12 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 98 113 1.1E-12 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695:SF1 177 208 9.2E-25 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695:SF1 141 160 9.2E-25 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695:SF1 7 113 9.2E-25 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695 177 208 9.2E-25 T 22-04-2016 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695 141 160 9.2E-25 T 22-04-2016 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 PANTHER PTHR33695 7 113 9.2E-25 T 22-04-2016 MED134_RS08880 5d89ff6dcd15b54094410dda03aff6bc 210 Pfam PF01252 Signal peptidase (SPase) II 9 194 1.5E-30 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 Pfam PF00920 Dehydratase family 36 554 2.0E-213 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 PANTHER PTHR21000:SF5 2 559 0.0 T 22-04-2016 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 557 1.3E-223 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 SUPERFAMILY SSF143975 3 378 1.18E-135 T 22-04-2016 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 557 42.771 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 SUPERFAMILY SSF52016 380 557 5.96E-57 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MED134_RS04740 46dfd15013ad3db2d73bab2629c19885 559 PANTHER PTHR21000 2 559 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Gene3D G3DSA:3.90.170.10 267 423 1.1E-66 T 22-04-2016 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 422 1.8E-155 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 424 171.755 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 SUPERFAMILY SSF52540 2 423 1.06E-151 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 22-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 SMART SM00788 3 423 3.1E-232 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 22-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Gene3D G3DSA:1.10.300.10 103 194 3.6E-25 T 22-04-2016 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Gene3D G3DSA:3.40.440.10 1 93 1.9E-63 T 22-04-2016 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Gene3D G3DSA:3.40.440.10 195 266 1.9E-63 T 22-04-2016 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 Pfam PF00709 Adenylosuccinate synthetase 6 422 1.1E-165 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS03855 3a76d185fac035ba4afbef5f86e69eff 424 PANTHER PTHR11846 2 424 1.1E-206 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 SUPERFAMILY SSF50621 284 445 2.93E-21 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 Gene3D G3DSA:2.40.37.10 298 457 4.2E-12 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 Gene3D G3DSA:3.20.20.10 52 297 7.5E-29 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 69 312 6.7E-16 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 SUPERFAMILY SSF51419 52 313 2.62E-38 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 PANTHER PTHR11482 24 469 8.9E-47 T 22-04-2016 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 PANTHER PTHR11482:SF36 24 469 8.9E-47 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MED134_RS01480 8d17916e90fe7c0fade1985a31b595e2 487 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 318 433 1.3E-13 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 SUPERFAMILY SSF82171 57 213 1.96E-12 T 22-04-2016 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 Gene3D G3DSA:3.40.50.1820 123 165 2.9E-87 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 Gene3D G3DSA:3.40.50.1820 358 655 2.9E-87 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 SUPERFAMILY SSF53474 395 655 1.64E-65 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 PANTHER PTHR11731:SF140 6 143 3.4E-104 T 22-04-2016 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 PANTHER PTHR11731:SF140 295 655 3.4E-104 T 22-04-2016 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 PANTHER PTHR11731 6 143 3.4E-104 T 22-04-2016 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 PANTHER PTHR11731 295 655 3.4E-104 T 22-04-2016 MED134_RS08600 7d7e3bf991d5111f7208fcd605d7a118 655 Pfam PF00326 Prolyl oligopeptidase family 441 655 7.3E-44 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MED134_RS14660 fa0e0471300e751c86b5958bb34e031b 184 SUPERFAMILY SSF46689 3 74 4.98E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS14660 fa0e0471300e751c86b5958bb34e031b 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.1E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS14660 fa0e0471300e751c86b5958bb34e031b 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.1E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS14660 fa0e0471300e751c86b5958bb34e031b 184 Gene3D G3DSA:1.10.357.10 2 173 1.6E-18 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS14660 fa0e0471300e751c86b5958bb34e031b 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 51 1.7E-11 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 Gene3D G3DSA:3.40.50.1820 4 255 4.4E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 Pfam PF00561 alpha/beta hydrolase fold 12 110 4.3E-21 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PANTHER PTHR10992:SF768 8 255 4.8E-67 T 22-04-2016 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PANTHER PTHR10992 8 255 4.8E-67 T 22-04-2016 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 SUPERFAMILY SSF53474 4 255 1.49E-46 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 4.3E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 4.3E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 4.3E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS07500 b435a4b10cb4228dc34cd01a2b7c1698 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 4.3E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 MED134_RS03900 4380beb8b0a73298a6a420d73568f73e 1275 Pfam PF13585 C-terminal domain of CHU protein family 1185 1273 1.5E-18 T 22-04-2016 MED134_RS00210 7ec708ca8606b9657f8eddf5a2f06134 571 PANTHER PTHR11819 2 297 2.3E-103 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS00210 7ec708ca8606b9657f8eddf5a2f06134 571 PANTHER PTHR11819 378 553 2.3E-103 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS00210 7ec708ca8606b9657f8eddf5a2f06134 571 Pfam PF00474 Sodium:solute symporter family 388 519 5.6E-13 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS00210 7ec708ca8606b9657f8eddf5a2f06134 571 Pfam PF00474 Sodium:solute symporter family 33 316 8.5E-25 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS11860 e300ce8ecc5388425e6f8a83fc2b57b7 547 PANTHER PTHR11819 1 528 4.0E-130 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS11860 e300ce8ecc5388425e6f8a83fc2b57b7 547 PANTHER PTHR11819:SF7 1 528 4.0E-130 T 22-04-2016 MED134_RS11860 e300ce8ecc5388425e6f8a83fc2b57b7 547 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 32 441 6.3E-92 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS11860 e300ce8ecc5388425e6f8a83fc2b57b7 547 Pfam PF00474 Sodium:solute symporter family 32 441 1.1E-55 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS09530 9fa99c782dfdf1380cd21de89f30da19 287 PANTHER PTHR30636 1 287 3.8E-72 T 22-04-2016 MED134_RS09530 9fa99c782dfdf1380cd21de89f30da19 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 1.3E-36 T 22-04-2016 IPR013527 YicC-like, N-terminal MED134_RS09530 9fa99c782dfdf1380cd21de89f30da19 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 286 1.2E-55 T 22-04-2016 IPR005229 Conserved hypothetical protein CHP00255 MED134_RS09530 9fa99c782dfdf1380cd21de89f30da19 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 286 2.6E-30 T 22-04-2016 IPR013551 Domain of unknown function DUF1732 MED134_RS07690 948c04f8ac5fc52cd273fa0382bf2d3b 304 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 1 291 1.7E-85 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS07690 948c04f8ac5fc52cd273fa0382bf2d3b 304 Pfam PF11751 Protein of unknown function (DUF3308) 20 289 9.4E-92 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS06755 5b9fe659c0af1f5b7c6eece87fe49df7 303 Pfam PF09084 NMT1/THI5 like 15 233 1.0E-47 T 22-04-2016 IPR015168 SsuA/THI5-like MED134_RS06755 5b9fe659c0af1f5b7c6eece87fe49df7 303 PANTHER PTHR31528:SF1 1 303 1.5E-68 T 22-04-2016 MED134_RS06755 5b9fe659c0af1f5b7c6eece87fe49df7 303 PANTHER PTHR31528 1 303 1.5E-68 T 22-04-2016 IPR027939 NMT1/THI5 family GO:0009228 UniPathway: UPA00060 MED134_RS06755 5b9fe659c0af1f5b7c6eece87fe49df7 303 SUPERFAMILY SSF53850 8 295 1.86E-25 T 22-04-2016 MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 Pfam PF02397 Bacterial sugar transferase 259 442 3.0E-57 T 22-04-2016 IPR003362 Bacterial sugar transferase MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 29 450 4.7E-126 T 22-04-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 PANTHER PTHR30576:SF0 4 450 1.3E-112 T 22-04-2016 MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 PANTHER PTHR30576 4 450 1.3E-112 T 22-04-2016 MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 Pfam PF13727 CoA-binding domain 56 207 8.8E-7 T 22-04-2016 MED134_RS09295 924bb06b619c0721d61e944abcb67938 450 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 33 446 1.1E-111 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MED134_RS03290 ee15ea7b7529d6c9fdee33be00569303 144 SUPERFAMILY SSF49764 20 137 7.48E-36 T 22-04-2016 IPR008978 HSP20-like chaperone MED134_RS03290 ee15ea7b7529d6c9fdee33be00569303 144 Gene3D G3DSA:2.60.40.790 24 144 7.5E-35 T 22-04-2016 IPR008978 HSP20-like chaperone MED134_RS03290 ee15ea7b7529d6c9fdee33be00569303 144 PANTHER PTHR11527:SF122 35 144 3.9E-31 T 22-04-2016 MED134_RS03290 ee15ea7b7529d6c9fdee33be00569303 144 Pfam PF00011 Hsp20/alpha crystallin family 41 144 3.6E-24 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain MED134_RS03290 ee15ea7b7529d6c9fdee33be00569303 144 PANTHER PTHR11527 35 144 3.9E-31 T 22-04-2016 IPR031107 Small heat shock protein HSP20 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 SUPERFAMILY SSF53790 8 238 2.36E-72 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 Gene3D G3DSA:3.30.950.10 125 240 2.9E-29 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 PIRSF PIRSF005917 1 239 1.1E-50 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 PANTHER PTHR21091:SF18 5 189 3.3E-19 T 22-04-2016 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 67 216 2.2E-8 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 MED134_RS13685 798be3af990ca83b3a589015ac4f46b9 241 PANTHER PTHR21091 5 189 3.3E-19 T 22-04-2016 MED134_RS04565 9604001c596206874e057e323cda8458 235 PANTHER PTHR42208:SF1 1 232 1.6E-29 T 22-04-2016 MED134_RS04565 9604001c596206874e057e323cda8458 235 PANTHER PTHR42208 1 232 1.6E-29 T 22-04-2016 MED134_RS04565 9604001c596206874e057e323cda8458 235 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 5 204 8.8E-55 T 22-04-2016 MED134_RS11450 344f0d7b939eb987a06857d97ef280a5 323 SUPERFAMILY SSF51261 173 298 4.29E-56 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS11450 344f0d7b939eb987a06857d97ef280a5 323 PANTHER PTHR21666 13 299 3.2E-47 T 22-04-2016 MED134_RS11450 344f0d7b939eb987a06857d97ef280a5 323 Pfam PF01551 Peptidase family M23 201 295 2.1E-35 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS11450 344f0d7b939eb987a06857d97ef280a5 323 Gene3D G3DSA:2.70.70.10 149 299 2.9E-53 T 22-04-2016 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 Gene3D G3DSA:3.30.70.660 113 258 6.1E-30 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 PIRSF PIRSF001430 5 259 1.2E-50 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 6 259 23.768 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 Gene3D G3DSA:3.30.70.580 7 106 1.4E-22 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 PANTHER PTHR11142 4 257 1.5E-52 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 SUPERFAMILY SSF55120 6 257 1.87E-53 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02880 43fee73332950f08cf672f2373060a1d 259 Pfam PF01416 tRNA pseudouridine synthase 149 257 8.3E-17 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 Gene3D G3DSA:3.40.50.261 120 288 4.3E-63 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 289 7.7E-122 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 Pfam PF00549 CoA-ligase 151 268 2.4E-12 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 SUPERFAMILY SSF52210 123 287 1.31E-49 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 Pfam PF02629 CoA binding domain 6 99 5.2E-29 T 22-04-2016 IPR003781 CoA-binding GO:0048037 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 SMART SM00881 4 100 3.1E-34 T 22-04-2016 IPR003781 CoA-binding GO:0048037 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 22-04-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PANTHER PTHR11117 1 289 5.6E-156 T 22-04-2016 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 SUPERFAMILY SSF51735 1 122 4.08E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PIRSF PIRSF001553 1 290 1.0E-120 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 2.7E-27 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 2.7E-27 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 2.7E-27 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 2.7E-27 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 MED134_RS02485 7330db9eb82f068cf45601806d118552 290 Gene3D G3DSA:3.40.50.720 2 119 8.0E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 SMART SM00830 277 357 5.9E-23 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 Gene3D G3DSA:3.20.20.70 14 262 2.5E-63 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 Pfam PF00793 DAHP synthetase I family 15 255 2.5E-35 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 SUPERFAMILY SSF48600 267 356 1.68E-22 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 PANTHER PTHR21057 19 275 2.9E-78 T 22-04-2016 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 Pfam PF01817 Chorismate mutase type II 277 355 6.4E-18 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 SUPERFAMILY SSF51569 15 263 4.21E-65 T 22-04-2016 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 Gene3D G3DSA:1.20.59.10 269 359 1.8E-21 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 MED134_RS05605 10cc4e83449d7bd008261bcb04cf0884 363 PANTHER PTHR21057:SF7 19 275 2.9E-78 T 22-04-2016 MED134_RS08190 a93eb294d34ca0d6472905a7f9a4bf87 162 PIRSF PIRSF037663 3 148 5.3E-11 T 22-04-2016 IPR017255 Acetyltransferase, GNAT, predicted MED134_RS08190 a93eb294d34ca0d6472905a7f9a4bf87 162 SUPERFAMILY SSF55729 3 158 8.06E-40 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08190 a93eb294d34ca0d6472905a7f9a4bf87 162 PANTHER PTHR10545 1 159 7.1E-58 T 22-04-2016 MED134_RS08190 a93eb294d34ca0d6472905a7f9a4bf87 162 Gene3D G3DSA:3.40.630.30 1 155 6.7E-55 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08190 a93eb294d34ca0d6472905a7f9a4bf87 162 Pfam PF00583 Acetyltransferase (GNAT) family 56 136 1.7E-18 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 Gene3D G3DSA:3.20.80.10 219 340 2.6E-11 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 Pfam PF06445 GyrI-like small molecule binding domain 274 339 3.9E-9 T 22-04-2016 IPR029442 GyrI-like small molecule binding domain MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 30 176 3.6E-7 T 22-04-2016 IPR019587 Polyketide cyclase/dehydrase MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 SUPERFAMILY SSF55136 209 340 1.59E-13 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 SMART SM00871 183 340 6.0E-4 T 22-04-2016 IPR010499 Bacterial transcription activator, effector binding MED134_RS03375 4571d90fad5bf11b87111bad59f9e4af 343 SUPERFAMILY SSF55961 20 175 3.76E-14 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PANTHER PTHR21087:SF0 1 168 2.1E-47 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 SUPERFAMILY SSF52540 1 172 5.71E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 Gene3D G3DSA:3.40.50.300 1 172 6.9E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PRINTS PR01100 Shikimate kinase family signature 27 40 2.3E-16 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PRINTS PR01100 Shikimate kinase family signature 97 114 2.3E-16 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PRINTS PR01100 Shikimate kinase family signature 75 84 2.3E-16 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PRINTS PR01100 Shikimate kinase family signature 3 18 2.3E-16 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PRINTS PR01100 Shikimate kinase family signature 55 63 2.3E-16 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 PANTHER PTHR21087 1 168 2.1E-47 T 22-04-2016 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 Hamap MF_00109 Shikimate kinase [aroK]. 1 173 22.794 T 22-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS12910 9d0eb8cc6f83a3c36eb43fe4f99d12d9 173 Pfam PF01202 Shikimate kinase 9 171 2.0E-40 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 PANTHER PTHR26402 4 145 2.0E-30 T 22-04-2016 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 Pfam PF00072 Response regulator receiver domain 6 113 8.7E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 SMART SM00448 4 115 2.4E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 Gene3D G3DSA:3.40.50.2300 4 135 2.6E-32 T 22-04-2016 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 SUPERFAMILY SSF53649 226 514 1.35E-10 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 SUPERFAMILY SSF52172 1 136 1.42E-33 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS02525 7c8094dc820f939f406dce7047c34d0a 515 Pfam PF08665 PglZ domain 230 421 4.5E-30 T 22-04-2016 IPR013973 PglZ domain MED134_RS05265 9252711864d17f10be036d7e1bc3bb5d 161 SUPERFAMILY SSF55729 1 142 2.06E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS05265 9252711864d17f10be036d7e1bc3bb5d 161 PANTHER PTHR13947:SF7 5 161 1.5E-35 T 22-04-2016 MED134_RS05265 9252711864d17f10be036d7e1bc3bb5d 161 PANTHER PTHR13947 5 161 1.5E-35 T 22-04-2016 MED134_RS05265 9252711864d17f10be036d7e1bc3bb5d 161 Gene3D G3DSA:3.40.630.30 2 161 1.8E-35 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS05265 9252711864d17f10be036d7e1bc3bb5d 161 Pfam PF00583 Acetyltransferase (GNAT) family 60 138 8.7E-16 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 PANTHER PTHR10366 1 265 1.7E-48 T 22-04-2016 MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 PANTHER PTHR10366 288 322 1.7E-48 T 22-04-2016 MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 SUPERFAMILY SSF51735 2 270 2.14E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 SUPERFAMILY SSF51735 297 325 2.14E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 226 1.2E-24 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS10735 5b7599386651a310031f8f356b45a6fe 329 Gene3D G3DSA:3.40.50.720 2 323 8.9E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 Pfam PF00005 ABC transporter 20 160 4.7E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 Gene3D G3DSA:3.40.50.300 3 224 3.9E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 SUPERFAMILY SSF52540 4 222 3.36E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 PANTHER PTHR24220:SF450 6 226 3.3E-93 T 22-04-2016 MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 Pfam PF13732 Domain of unknown function (DUF4162) 214 308 1.4E-14 T 22-04-2016 IPR025302 Domain of unknown function DUF4162 MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 PANTHER PTHR24220 6 226 3.3E-93 T 22-04-2016 MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 SMART SM00382 29 208 4.8E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13210 7c8cf7ae5d732b0fbbc17c7510e6cc5f 312 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 Gene3D G3DSA:1.25.40.10 118 237 4.9E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 SUPERFAMILY SSF46689 548 600 1.3E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 SMART SM00342 511 598 1.0E-13 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 Gene3D G3DSA:1.10.10.60 564 593 7.0E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 SUPERFAMILY SSF48452 147 379 8.35E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 Pfam PF12833 Helix-turn-helix domain 517 598 3.6E-13 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS02545 c4fe59abcefd5d870c5e5505545f3c9f 627 Gene3D G3DSA:1.25.40.10 238 377 1.3E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 PANTHER PTHR23416:SF55 22 179 1.5E-31 T 22-04-2016 MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 PIRSF PIRSF000441 1 180 2.4E-47 T 22-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 PANTHER PTHR23416 22 179 1.5E-31 T 22-04-2016 MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 Gene3D G3DSA:2.160.10.10 55 174 2.5E-25 T 22-04-2016 MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 SUPERFAMILY SSF51161 36 179 1.94E-34 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS13455 b875d50ad33b9b552382b0880100485c 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 123 154 1.6E-4 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS10720 a033468386bbf3d5bd4c28c8aab46ce4 240 SUPERFAMILY SSF53448 5 219 2.4E-45 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS10720 a033468386bbf3d5bd4c28c8aab46ce4 240 Pfam PF00535 Glycosyl transferase family 2 6 164 3.9E-30 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS10720 a033468386bbf3d5bd4c28c8aab46ce4 240 PANTHER PTHR10859 6 238 6.3E-66 T 22-04-2016 MED134_RS10720 a033468386bbf3d5bd4c28c8aab46ce4 240 Gene3D G3DSA:3.90.550.10 6 218 8.0E-24 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 PANTHER PTHR15160:SF1 14 202 1.9E-38 T 22-04-2016 MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 Pfam PF02151 UvrB/uvrC motif 174 202 3.2E-8 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 Gene3D G3DSA:4.10.860.10 173 201 5.8E-5 T 22-04-2016 IPR001943 UVR domain GO:0005515 MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 PANTHER PTHR15160 14 202 1.9E-38 T 22-04-2016 MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 SUPERFAMILY SSF103256 3 138 1.31E-39 T 22-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 MED134_RS07215 4791bd5d7ae76194eb6a140941b49741 204 Pfam PF02577 Bifunctional nuclease 8 135 4.8E-43 T 22-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PANTHER PTHR10458 1 179 2.1E-64 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 171 2.2E-41 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 Gene3D G3DSA:3.90.45.10 3 185 2.8E-60 T 22-04-2016 IPR023635 Peptide deformylase MED134_RS04320 27191b1307657e7505530c4f66a822af 196 Pfam PF01327 Polypeptide deformylase 3 166 6.1E-49 T 22-04-2016 IPR023635 Peptide deformylase MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PIRSF PIRSF004749 1 189 3.9E-51 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PRINTS PR01576 Peptide deformylase signature 115 133 3.0E-32 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PRINTS PR01576 Peptide deformylase signature 103 114 3.0E-32 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PRINTS PR01576 Peptide deformylase signature 134 163 3.0E-32 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 PRINTS PR01576 Peptide deformylase signature 32 61 3.0E-32 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS04320 27191b1307657e7505530c4f66a822af 196 SUPERFAMILY SSF56420 1 178 4.06E-57 T 22-04-2016 IPR023635 Peptide deformylase MED134_RS04320 27191b1307657e7505530c4f66a822af 196 Hamap MF_00163 Peptide deformylase [def]. 1 176 27.766 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 MED134_RS01525 19a97ecda904db91c95331a4fff02b38 251 PANTHER PTHR11351:SF34 1 238 1.2E-35 T 22-04-2016 MED134_RS01525 19a97ecda904db91c95331a4fff02b38 251 Pfam PF00487 Fatty acid desaturase 4 222 4.5E-19 T 22-04-2016 IPR005804 Fatty acid desaturase domain GO:0006629 MED134_RS01525 19a97ecda904db91c95331a4fff02b38 251 PANTHER PTHR11351 1 238 1.2E-35 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 PANTHER PTHR10366 232 352 7.4E-129 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 PANTHER PTHR10366 12 197 7.4E-129 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 Gene3D G3DSA:3.40.50.720 12 244 1.9E-69 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 Gene3D G3DSA:3.90.25.10 318 353 2.1E-13 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 Gene3D G3DSA:3.90.25.10 245 260 2.1E-13 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 PANTHER PTHR10366:SF246 12 197 7.4E-129 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 PANTHER PTHR10366:SF246 232 352 7.4E-129 T 22-04-2016 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 284 1.8E-74 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 SUPERFAMILY SSF51735 8 197 1.63E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 SUPERFAMILY SSF51735 231 353 1.63E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09245 05fb140fab717ad0be09bd5d1ffea9d0 354 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 10 352 48.651 T 22-04-2016 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|UniPathway: UPA00128 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 Gene3D G3DSA:1.10.1020.10 81 174 1.1E-28 T 22-04-2016 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 TIGRFAM TIGR00571 dam: DNA adenine methylase 24 288 6.2E-73 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 199 205 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 29 267 1.6E-51 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 Gene3D G3DSA:3.40.50.150 18 80 5.1E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 Gene3D G3DSA:3.40.50.150 180 289 5.1E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 SUPERFAMILY SSF53335 23 289 1.11E-66 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PANTHER PTHR30481:SF3 6 289 1.1E-73 T 22-04-2016 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PANTHER PTHR30481 6 289 1.1E-73 T 22-04-2016 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 29 45 4.0E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 71 84 4.0E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 52 66 4.0E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 196 208 4.0E-14 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MED134_RS03690 6c92a5deb12716ab68cb112a67e75872 289 PIRSF PIRSF000398 20 289 1.8E-56 T 22-04-2016 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PANTHER PTHR30194 1 174 1.3E-56 T 22-04-2016 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 7 155 3.4E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 5 158 40.125 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 Gene3D G3DSA:3.30.420.10 6 160 3.1E-52 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 117 152 - T 22-04-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 8 21 2.6E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 87 103 2.6E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 65 81 2.6E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 111 130 2.6E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 143 155 2.6E-29 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 7 157 2.4E-39 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MED134_RS10370 6c6f02ca847e89ea4803c75cab289808 184 SUPERFAMILY SSF53098 6 159 1.11E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 282 301 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 135 153 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 433 448 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 58 83 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 268 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 153 172 1.5E-24 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 Pfam PF01019 Gamma-glutamyltranspeptidase 51 491 2.3E-63 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 PANTHER PTHR11686 49 316 2.1E-58 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS03680 2c42ec0ed4258507f408c37936229ac5 564 SUPERFAMILY SSF56235 40 542 4.44E-79 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 PANTHER PTHR21235 2 251 1.4E-114 T 22-04-2016 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 46.419 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 Gene3D G3DSA:3.20.20.70 4 251 1.1E-97 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 PANTHER PTHR21235:SF2 2 251 1.4E-114 T 22-04-2016 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 250 2.0E-106 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 SUPERFAMILY SSF51366 3 250 1.02E-78 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS02910 c82649bf3fc2a99722c3781e28bdc50e 251 Pfam PF00977 Histidine biosynthesis protein 5 233 2.9E-86 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 PANTHER PTHR11699:SF15 3 456 3.0E-208 T 22-04-2016 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 PANTHER PTHR11699 3 456 3.0E-208 T 22-04-2016 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 Gene3D G3DSA:3.40.309.10 224 407 5.2E-57 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 Pfam PF00171 Aldehyde dehydrogenase family 15 427 6.6E-90 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 Gene3D G3DSA:3.40.605.10 6 223 5.4E-62 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 SUPERFAMILY SSF53720 6 443 1.57E-118 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 236 247 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 PIRSF PIRSF036492 2 456 8.1E-181 T 22-04-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 MED134_RS04745 11162f663d377fb44f6a7739cf072e5e 457 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 208 215 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 SMART SM00448 1 109 2.3E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 PANTHER PTHR26402:SF522 1 118 6.8E-21 T 22-04-2016 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 Gene3D G3DSA:2.40.50.40 143 212 1.1E-13 T 22-04-2016 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 Pfam PF00072 Response regulator receiver domain 3 110 1.1E-15 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 PANTHER PTHR26402 1 118 6.8E-21 T 22-04-2016 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 SMART SM00850 152 252 1.9E-24 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 SUPERFAMILY SSF52172 1 136 1.99E-23 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 Gene3D G3DSA:3.40.50.2300 1 117 3.9E-23 T 22-04-2016 MED134_RS00935 a5a0138cb17e1b092edd7b06925185f4 252 Pfam PF04397 LytTr DNA-binding domain 154 251 8.4E-21 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS12805 647d056544460bdf636275e1018434f4 317 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 40 315 7.9E-107 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MED134_RS12805 647d056544460bdf636275e1018434f4 317 Gene3D G3DSA:3.40.50.300 111 316 7.7E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12805 647d056544460bdf636275e1018434f4 317 SMART SM00382 115 295 2.9E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS12805 647d056544460bdf636275e1018434f4 317 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 40 317 59.497 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MED134_RS12805 647d056544460bdf636275e1018434f4 317 SUPERFAMILY SSF52540 111 316 2.23E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12805 647d056544460bdf636275e1018434f4 317 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 290 303 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS12805 647d056544460bdf636275e1018434f4 317 PANTHER PTHR11564:SF16 10 317 9.6E-123 T 22-04-2016 MED134_RS12805 647d056544460bdf636275e1018434f4 317 Pfam PF00448 SRP54-type protein, GTPase domain 116 316 4.5E-76 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS12805 647d056544460bdf636275e1018434f4 317 Gene3D G3DSA:1.20.120.140 18 101 2.4E-27 T 22-04-2016 MED134_RS12805 647d056544460bdf636275e1018434f4 317 Pfam PF02881 SRP54-type protein, helical bundle domain 28 93 1.3E-11 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS12805 647d056544460bdf636275e1018434f4 317 SMART SM00962 116 317 7.8E-114 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS12805 647d056544460bdf636275e1018434f4 317 PANTHER PTHR11564 10 317 9.6E-123 T 22-04-2016 MED134_RS12805 647d056544460bdf636275e1018434f4 317 SUPERFAMILY SSF47364 14 91 8.64E-18 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS12805 647d056544460bdf636275e1018434f4 317 SMART SM00963 16 97 2.3E-18 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 MED134_RS09615 a534f7c50b9b98ffce26d15bc65fb656 204 Gene3D G3DSA:3.40.30.10 12 203 4.4E-58 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS09615 a534f7c50b9b98ffce26d15bc65fb656 204 Pfam PF14595 Thioredoxin 40 169 1.0E-44 T 22-04-2016 MED134_RS09615 a534f7c50b9b98ffce26d15bc65fb656 204 SUPERFAMILY SSF52833 62 160 7.04E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS13630 19e2ca4e309cfc0b8f5b64d1777b4288 370 PANTHER PTHR12526 19 370 1.8E-39 T 22-04-2016 MED134_RS13630 19e2ca4e309cfc0b8f5b64d1777b4288 370 Pfam PF00534 Glycosyl transferases group 1 197 349 3.3E-35 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS13630 19e2ca4e309cfc0b8f5b64d1777b4288 370 SUPERFAMILY SSF53756 20 370 8.97E-57 T 22-04-2016 MED134_RS13630 19e2ca4e309cfc0b8f5b64d1777b4288 370 Pfam PF13439 Glycosyltransferase Family 4 30 183 7.1E-9 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS13630 19e2ca4e309cfc0b8f5b64d1777b4288 370 Gene3D G3DSA:3.40.50.2000 199 348 2.2E-18 T 22-04-2016 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Gene3D G3DSA:3.40.50.620 108 200 3.0E-89 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Gene3D G3DSA:3.40.50.620 269 519 3.0E-89 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SUPERFAMILY SSF47323 520 643 1.37E-27 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PANTHER PTHR11956 275 643 7.1E-153 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PANTHER PTHR11956 1 206 7.1E-153 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Pfam PF00750 tRNA synthetases class I (R) 250 501 3.9E-29 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 643 22.92 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SUPERFAMILY SSF52374 108 200 1.57E-69 T 22-04-2016 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SUPERFAMILY SSF52374 269 518 1.57E-69 T 22-04-2016 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Gene3D G3DSA:1.10.730.10 520 643 2.1E-30 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PANTHER PTHR11956:SF6 275 643 7.1E-153 T 22-04-2016 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PANTHER PTHR11956:SF6 1 206 7.1E-153 T 22-04-2016 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 267 643 5.9E-83 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SUPERFAMILY SSF55190 8 96 2.09E-7 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 3.5E-9 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 3.5E-9 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 3.5E-9 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SMART SM00836 526 643 2.0E-41 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 84 9.8E-7 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Gene3D G3DSA:3.30.1360.70 6 100 6.7E-10 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 121 132 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 Pfam PF05746 DALR anticodon binding domain 526 643 4.0E-27 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MED134_RS05450 9cef15f543cfb02200f8f6c60dd7a9b5 643 SMART SM01016 5 86 4.4E-7 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Pfam PF00691 OmpA family 430 517 2.4E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Pfam PF13620 Carboxypeptidase regulatory-like domain 326 397 2.1E-9 T 22-04-2016 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Pfam PF07676 WD40-like Beta Propeller Repeat 177 211 0.0017 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Pfam PF07676 WD40-like Beta Propeller Repeat 243 265 0.026 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 PRINTS PR01021 OMPA domain signature 476 492 4.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 PRINTS PR01021 OMPA domain signature 431 453 4.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 PRINTS PR01021 OMPA domain signature 461 476 4.2E-9 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Gene3D G3DSA:2.60.40.1120 327 409 1.1E-7 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 PANTHER PTHR30128 407 537 1.4E-34 T 22-04-2016 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 SUPERFAMILY SSF49478 326 394 7.45E-8 T 22-04-2016 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 SUPERFAMILY SSF82171 125 265 4.84E-14 T 22-04-2016 MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 SUPERFAMILY SSF103088 404 533 1.31E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Gene3D G3DSA:2.120.10.30 121 267 1.2E-13 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS07465 1b8f2574d551170715de6e937f20590e 537 Gene3D G3DSA:3.30.1330.60 417 534 2.5E-33 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 Pfam PF00916 Sulfate permease family 8 148 5.9E-31 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 Pfam PF00916 Sulfate permease family 212 427 6.7E-43 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 Gene3D G3DSA:3.30.750.24 512 618 3.5E-12 T 22-04-2016 IPR002645 STAS domain MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 Pfam PF01740 STAS domain 513 612 1.8E-10 T 22-04-2016 IPR002645 STAS domain MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 PANTHER PTHR11814 1 150 9.2E-146 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 PANTHER PTHR11814 209 621 9.2E-146 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 PANTHER PTHR11814:SF97 1 150 9.2E-146 T 22-04-2016 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 PANTHER PTHR11814:SF97 209 621 9.2E-146 T 22-04-2016 MED134_RS09905 15d5eb0c0a776b623c91e6e0f4d38a0e 625 SUPERFAMILY SSF52091 511 617 4.71E-12 T 22-04-2016 IPR002645 STAS domain MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 Gene3D G3DSA:1.20.1290.10 13 104 5.0E-28 T 22-04-2016 IPR029032 AhpD-like MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 PANTHER PTHR33930:SF4 4 109 1.8E-43 T 22-04-2016 MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 PANTHER PTHR33930 4 109 1.8E-43 T 22-04-2016 MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 SUPERFAMILY SSF69118 13 105 2.88E-22 T 22-04-2016 IPR029032 AhpD-like MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 97 6.2E-17 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 TIGRFAM TIGR04169 perox_w_seleSAM: alkylhydroperoxidase/carboxymuconolactone decarboxylase family protein 3 109 7.6E-58 T 22-04-2016 IPR026445 Alkylhydroperoxidase/carboxymuconolactone decarboxylase family MED134_RS06525 bdf44857203e2d47dbd586f31baaf56d 111 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 39 88 9.8E-14 T 22-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 182 1.2E-38 T 22-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 Pfam PF00156 Phosphoribosyl transferase domain 49 150 5.8E-16 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 PANTHER PTHR19278 1 208 2.6E-56 T 22-04-2016 MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 26.552 T 22-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 Gene3D G3DSA:3.40.50.2020 6 211 1.2E-52 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS12950 a1ab78844943bb9e06c489e4e3d91d08 212 SUPERFAMILY SSF53271 13 211 1.7E-51 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 Gene3D G3DSA:2.40.50.100 101 134 1.2E-18 T 22-04-2016 MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 Gene3D G3DSA:2.40.50.100 195 227 1.2E-18 T 22-04-2016 MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 90 300 2.3E-28 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 PANTHER PTHR30469 64 385 2.2E-57 T 22-04-2016 MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 77 385 7.9E-66 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 SUPERFAMILY SSF111369 90 304 9.55E-31 T 22-04-2016 MED134_RS07385 14d87ad15985f4fa437a4630aa4f53db 388 PANTHER PTHR30469:SF15 64 385 2.2E-57 T 22-04-2016 MED134_RS10215 639e537bd5c9d11bbee8c2f761368a3a 112 Gene3D G3DSA:2.60.120.380 43 104 8.4E-4 T 22-04-2016 MED134_RS10215 639e537bd5c9d11bbee8c2f761368a3a 112 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 47 111 9.7E-9 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 PANTHER PTHR13528 1 71 1.7E-29 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 SUPERFAMILY SSF143800 1 77 1.73E-28 T 22-04-2016 MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 3.5E-27 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 Pfam PF00830 Ribosomal L28 family 3 62 1.4E-25 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.249 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05075 10cd52f06d282df3170283c3266ce8da 79 Gene3D G3DSA:2.30.170.40 2 75 1.9E-34 T 22-04-2016 MED134_RS04035 a55327af401588f39723cbf9da6403ff 100 SUPERFAMILY SSF46785 3 99 2.5E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04035 a55327af401588f39723cbf9da6403ff 100 Gene3D G3DSA:1.10.10.10 2 99 3.7E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04035 a55327af401588f39723cbf9da6403ff 100 PANTHER PTHR33154 11 99 4.3E-14 T 22-04-2016 MED134_RS04035 a55327af401588f39723cbf9da6403ff 100 SMART SM00418 8 97 1.7E-4 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS04035 a55327af401588f39723cbf9da6403ff 100 Pfam PF01022 Bacterial regulatory protein, arsR family 46 75 3.1E-5 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 SUPERFAMILY SSF53383 13 375 1.35E-108 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 Gene3D G3DSA:3.90.1150.10 252 376 5.0E-36 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 PANTHER PTHR30244 1 377 1.1E-115 T 22-04-2016 MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 PANTHER PTHR30244:SF15 1 377 1.1E-115 T 22-04-2016 MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 Gene3D G3DSA:3.40.640.10 15 250 9.9E-82 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 370 4.4E-117 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS07305 ce6afa5b8331ff96d6b140024869ebc9 377 PIRSF PIRSF000390 3 377 8.5E-105 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 Gene3D G3DSA:3.50.30.30 473 559 2.2E-23 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 Pfam PF02225 PA domain 470 547 3.5E-13 T 22-04-2016 IPR003137 PA domain MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 SUPERFAMILY SSF52025 478 549 1.83E-12 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 48 86 1.1E-4 T 22-04-2016 IPR011096 FTP domain MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 PANTHER PTHR33478 42 416 2.2E-88 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 PANTHER PTHR33478 570 806 2.2E-88 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 SUPERFAMILY SSF55486 576 783 2.2E-56 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 SUPERFAMILY SSF55486 268 413 2.2E-56 T 22-04-2016 MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 827 900 9.3E-14 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS11040 94019a2387c8fc480fa7adcd3253e6d0 900 Pfam PF02128 Fungalysin metallopeptidase (M36) 244 786 2.0E-145 T 22-04-2016 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MED134_RS06515 a242d6707d388af9594ccc2554b1e7f6 258 PANTHER PTHR30164 1 250 4.5E-52 T 22-04-2016 MED134_RS06515 a242d6707d388af9594ccc2554b1e7f6 258 SUPERFAMILY SSF55486 60 251 4.69E-39 T 22-04-2016 MED134_RS06515 a242d6707d388af9594ccc2554b1e7f6 258 Pfam PF06167 Glucose-regulated metallo-peptidase M90 25 254 6.4E-62 T 22-04-2016 IPR010384 MtfA family MED134_RS06515 a242d6707d388af9594ccc2554b1e7f6 258 Gene3D G3DSA:3.40.390.10 42 254 9.3E-49 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 Gene3D G3DSA:3.40.50.20 7 115 5.1E-30 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 SUPERFAMILY SSF51246 310 381 2.51E-13 T 22-04-2016 IPR011054 Rudiment single hybrid motif MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 Pfam PF02222 ATP-grasp domain 116 283 3.7E-46 T 22-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 367 4.3E-114 T 22-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 Gene3D G3DSA:3.30.470.20 149 381 1.4E-78 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 PANTHER PTHR11609 11 370 1.4E-123 T 22-04-2016 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 365 37.797 T 22-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 SUPERFAMILY SSF56059 107 304 2.05E-49 T 22-04-2016 MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 SUPERFAMILY SSF52440 6 103 2.59E-22 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS12015 30700e770e7805e8fa4a389accec4f55 384 PANTHER PTHR11609:SF5 11 370 1.4E-123 T 22-04-2016 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 Gene3D G3DSA:3.40.50.300 369 599 8.6E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 ProSitePatterns PS00211 ABC transporters family signature. 506 520 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 Pfam PF00664 ABC transporter transmembrane region 20 315 1.1E-37 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 PANTHER PTHR24221 4 48 1.7E-205 T 22-04-2016 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 PANTHER PTHR24221 82 608 1.7E-205 T 22-04-2016 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 Gene3D G3DSA:1.20.1560.10 4 351 2.1E-67 T 22-04-2016 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 SMART SM00382 394 580 1.3E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 SUPERFAMILY SSF90123 5 49 2.49E-64 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 SUPERFAMILY SSF90123 84 351 2.49E-64 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 Pfam PF00005 ABC transporter 385 534 2.5E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS03485 487530be16570d748cdcf3b771a5f6fa 608 SUPERFAMILY SSF52540 366 604 6.61E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07560 69fce54c2f91543f3d0e62a20c59e472 390 Pfam PF00092 von Willebrand factor type A domain 51 199 2.3E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS07560 69fce54c2f91543f3d0e62a20c59e472 390 Gene3D G3DSA:3.40.50.410 49 203 3.1E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS07560 69fce54c2f91543f3d0e62a20c59e472 390 SUPERFAMILY SSF53300 49 225 4.28E-19 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS02785 af12ea000ff13382cf91e129e05bb82e 268 Pfam PF13559 Domain of unknown function (DUF4129) 195 257 1.3E-5 T 22-04-2016 IPR025403 Domain of unknown function DUF4129 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 Gene3D G3DSA:3.40.50.720 140 300 6.2E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 PANTHER PTHR11695:SF528 22 333 5.6E-126 T 22-04-2016 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 Pfam PF00107 Zinc-binding dehydrogenase 157 292 2.7E-20 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 Gene3D G3DSA:3.90.180.10 2 139 2.8E-52 T 22-04-2016 IPR011032 GroES-like MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 PANTHER PTHR11695 22 333 5.6E-126 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 SUPERFAMILY SSF50129 1 142 1.14E-36 T 22-04-2016 IPR011032 GroES-like MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 SUPERFAMILY SSF50129 285 332 1.6E-5 T 22-04-2016 IPR011032 GroES-like MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 SMART SM00829 18 331 2.2E-7 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 Pfam PF16884 N-terminal domain of oxidoreductase 5 112 5.9E-38 T 22-04-2016 MED134_RS01130 b7295bb70882069e2f19ef6e4d2862d3 333 SUPERFAMILY SSF51735 123 298 6.73E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 19 194 1.1E-76 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 122 132 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 PANTHER PTHR11109 21 193 1.1E-109 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 Gene3D G3DSA:1.10.286.10 15 64 9.3E-18 T 22-04-2016 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 74 90 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 SUPERFAMILY SSF55620 14 194 9.64E-78 T 22-04-2016 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 Pfam PF01227 GTP cyclohydrolase I 18 193 3.7E-76 T 22-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 Gene3D G3DSA:3.30.1130.10 67 194 5.7E-64 T 22-04-2016 MED134_RS02000 e7b04d9c5a8bae5566e3319d0ee5ce24 198 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 13 194 37.653 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 SMART SM00487 285 512 1.5E-13 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 Pfam PF04851 Type III restriction enzyme, res subunit 289 490 4.3E-16 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 SUPERFAMILY SSF52540 255 437 2.94E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 SUPERFAMILY SSF52540 478 536 2.94E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 78 224 4.1E-15 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 PANTHER PTHR30195:SF13 1 440 0.0 T 22-04-2016 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 PANTHER PTHR30195:SF13 468 966 0.0 T 22-04-2016 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 Gene3D G3DSA:3.40.50.300 278 493 1.5E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 PANTHER PTHR30195 1 440 0.0 T 22-04-2016 MED134_RS00500 e2c85b39d16228199182ec458ce2f2e3 1022 PANTHER PTHR30195 468 966 0.0 T 22-04-2016 MED134_RS01425 0d914bb894834b0d023d9fd0cd9098b0 177 PANTHER PTHR30576 1 177 3.5E-50 T 22-04-2016 MED134_RS01425 0d914bb894834b0d023d9fd0cd9098b0 177 Pfam PF02397 Bacterial sugar transferase 3 176 1.6E-47 T 22-04-2016 IPR003362 Bacterial sugar transferase MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 PANTHER PTHR30346:SF15 1 312 1.9E-83 T 22-04-2016 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 SUPERFAMILY SSF46785 1 86 4.36E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.7E-20 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 PANTHER PTHR30346 1 312 1.9E-83 T 22-04-2016 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 Gene3D G3DSA:3.40.190.10 91 175 6.3E-22 T 22-04-2016 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 Gene3D G3DSA:1.10.10.10 1 84 6.7E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 SUPERFAMILY SSF53850 90 292 1.83E-36 T 22-04-2016 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 Gene3D G3DSA:3.40.190.10 176 269 5.1E-19 T 22-04-2016 MED134_RS00195 bf5ecdf6d95061ebe79f1855278eca3c 312 Pfam PF03466 LysR substrate binding domain 89 291 1.9E-37 T 22-04-2016 IPR005119 LysR, substrate-binding MED134_RS14285 37722a24347fd88364793a3c9a1bb1c6 357 Gene3D G3DSA:3.60.10.10 93 307 3.6E-6 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS14285 37722a24347fd88364793a3c9a1bb1c6 357 SUPERFAMILY SSF56219 95 310 3.01E-29 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS14285 37722a24347fd88364793a3c9a1bb1c6 357 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 99 305 5.0E-21 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS14765 e75bb31c45939a9dbdabbdc8b2f8f986 320 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 16 304 7.9E-9 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 Pfam PF00793 DAHP synthetase I family 9 265 1.3E-56 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 PANTHER PTHR21057:SF2 9 269 8.8E-132 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 SUPERFAMILY SSF51569 6 270 8.06E-93 T 22-04-2016 MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 Gene3D G3DSA:3.20.20.70 15 270 3.1E-104 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 PANTHER PTHR21057 9 269 8.8E-132 T 22-04-2016 MED134_RS05915 ef351bc90184ce43ee4d684535765715 272 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 16 269 6.3E-109 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 PANTHER PTHR11918:SF45 5 438 9.8E-119 T 22-04-2016 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 Gene3D G3DSA:3.80.30.20 147 383 2.2E-66 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 153 173 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 9 428 5.2E-128 T 22-04-2016 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 PANTHER PTHR11918 5 438 9.8E-119 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 SMART SM00729 149 371 7.7E-43 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 Pfam PF00919 Uncharacterized protein family UPF0004 6 101 2.3E-23 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 SUPERFAMILY SSF102114 145 384 2.88E-49 T 22-04-2016 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 436 7.6E-117 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 MED134_RS13735 5532f37d6c52932aa8d19910418b7387 447 Pfam PF04055 Radical SAM superfamily 155 329 1.2E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS13870 614804995a57d65894577c5600ecf842 388 SUPERFAMILY SSF82861 16 87 3.27E-5 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MED134_RS13870 614804995a57d65894577c5600ecf842 388 Pfam PF05552 Conserved TM helix 15 52 2.7E-9 T 22-04-2016 IPR008910 Conserved TM helix MED134_RS13870 614804995a57d65894577c5600ecf842 388 Pfam PF05552 Conserved TM helix 93 140 2.7E-11 T 22-04-2016 IPR008910 Conserved TM helix MED134_RS13870 614804995a57d65894577c5600ecf842 388 Pfam PF05552 Conserved TM helix 183 231 2.0E-8 T 22-04-2016 IPR008910 Conserved TM helix MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 Gene3D G3DSA:3.40.50.720 2 262 5.5E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.3E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.3E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.3E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 260 1.5E-42 T 22-04-2016 MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 SUPERFAMILY SSF51735 6 262 7.61E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PANTHER PTHR24321:SF6 3 262 4.5E-14 T 22-04-2016 MED134_RS02630 532e7be05906c085b9a2854aa0bd1d5f 263 PANTHER PTHR24321 3 262 4.5E-14 T 22-04-2016 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 PANTHER PTHR22854:SF2 1 258 1.4E-85 T 22-04-2016 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 256 30.574 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 249 4.2E-77 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 PANTHER PTHR22854 1 258 1.4E-85 T 22-04-2016 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 SUPERFAMILY SSF51366 10 255 7.35E-76 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS13035 8fbaf0ead61cc792767a9687b71d2452 258 Gene3D G3DSA:3.20.20.70 1 255 9.7E-88 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS04620 679581e0118d455f298e1546e9e84919 283 Pfam PF00582 Universal stress protein family 2 139 7.7E-14 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04620 679581e0118d455f298e1546e9e84919 283 Gene3D G3DSA:3.40.50.620 1 144 2.4E-19 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04620 679581e0118d455f298e1546e9e84919 283 SUPERFAMILY SSF52402 3 153 1.26E-20 T 22-04-2016 MED134_RS04620 679581e0118d455f298e1546e9e84919 283 PRINTS PR01438 Universal stress protein signature 107 119 7.5E-5 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04620 679581e0118d455f298e1546e9e84919 283 PRINTS PR01438 Universal stress protein signature 2 20 7.5E-5 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04620 679581e0118d455f298e1546e9e84919 283 Gene3D G3DSA:3.40.50.620 145 278 1.5E-7 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04620 679581e0118d455f298e1546e9e84919 283 SUPERFAMILY SSF52402 157 279 1.0E-12 T 22-04-2016 MED134_RS09955 c8cad100f0788a623ae29d2616e53514 288 Pfam PF01882 Protein of unknown function DUF58 37 122 4.3E-21 T 22-04-2016 IPR002881 Domain of unknown function DUF58 MED134_RS09955 c8cad100f0788a623ae29d2616e53514 288 SUPERFAMILY SSF53300 73 200 8.39E-14 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09955 c8cad100f0788a623ae29d2616e53514 288 PANTHER PTHR33608 1 287 7.8E-86 T 22-04-2016 MED134_RS09955 c8cad100f0788a623ae29d2616e53514 288 Gene3D G3DSA:3.40.50.410 80 199 2.7E-4 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS09955 c8cad100f0788a623ae29d2616e53514 288 PANTHER PTHR33608:SF5 1 287 7.8E-86 T 22-04-2016 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 PANTHER PTHR18866 1 443 3.3E-296 T 22-04-2016 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 SUPERFAMILY SSF52440 1 113 7.12E-49 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 3.1E-218 T 22-04-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Gene3D G3DSA:3.30.470.20 203 441 3.4E-99 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 SUPERFAMILY SSF51246 331 442 2.62E-46 T 22-04-2016 IPR011054 Rudiment single hybrid motif MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 9.3E-73 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 1.5E-44 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Gene3D G3DSA:3.40.50.20 1 129 2.3E-53 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 SUPERFAMILY SSF56059 83 350 3.71E-65 T 22-04-2016 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 6.1E-46 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 Gene3D G3DSA:3.30.1490.20 130 201 5.5E-29 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS06675 6c66d6a7cc5387b84c0488b562a4e8fb 449 SMART SM00878 334 440 2.2E-71 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 SMART SM00382 27 209 3.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 SUPERFAMILY SSF52540 2 224 1.07E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 Pfam PF00005 ABC transporter 19 163 4.2E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 PANTHER PTHR24220 4 222 3.4E-101 T 22-04-2016 MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 PANTHER PTHR24220:SF571 4 222 3.4E-101 T 22-04-2016 MED134_RS06360 7841cf5699e2375dc69a1555da2cb671 296 Gene3D G3DSA:3.40.50.300 2 223 3.7E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 ProSitePatterns PS00123 Alkaline phosphatase active site. 80 88 - T 22-04-2016 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PRINTS PR00113 Alkaline phosphatase signature 161 171 1.96E-26 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PRINTS PR00113 Alkaline phosphatase signature 33 53 1.96E-26 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PRINTS PR00113 Alkaline phosphatase signature 229 258 1.96E-26 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PRINTS PR00113 Alkaline phosphatase signature 117 137 1.96E-26 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 SMART SM00098 34 363 1.4E-49 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PANTHER PTHR11596:SF5 29 357 4.2E-93 T 22-04-2016 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 PANTHER PTHR11596 29 357 4.2E-93 T 22-04-2016 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 Gene3D G3DSA:3.40.720.10 16 361 7.9E-105 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 Pfam PF00245 Alkaline phosphatase 34 309 3.9E-69 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 Pfam PF00245 Alkaline phosphatase 322 360 8.9E-5 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MED134_RS11945 b9e866d25082beb91a4134db3af6903e 363 SUPERFAMILY SSF53649 14 359 6.28E-107 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MED134_RS02810 68524f1e841847e679ce25d489d5646f 448 PIRSF PIRSF002746 1 448 1.7E-154 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MED134_RS02810 68524f1e841847e679ce25d489d5646f 448 PANTHER PTHR30354:SF1 1 447 5.6E-140 T 22-04-2016 MED134_RS02810 68524f1e841847e679ce25d489d5646f 448 Pfam PF02447 GntP family permease 6 444 1.1E-141 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MED134_RS02810 68524f1e841847e679ce25d489d5646f 448 PANTHER PTHR30354 1 447 5.6E-140 T 22-04-2016 MED134_RS02810 68524f1e841847e679ce25d489d5646f 448 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 6 447 1.9E-134 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 Pfam PF01235 Sodium:alanine symporter family 102 508 4.6E-127 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PANTHER PTHR30330:SF3 28 84 2.0E-165 T 22-04-2016 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PANTHER PTHR30330:SF3 104 503 2.0E-165 T 22-04-2016 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PANTHER PTHR30330 28 84 2.0E-165 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PANTHER PTHR30330 104 503 2.0E-165 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 TIGRFAM TIGR00835 agcS: amino acid carrier protein 46 501 1.0E-110 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 470 490 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 243 261 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 361 379 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 271 290 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 138 160 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS14345 b32892842ccbc8b9e623abbba936a608 509 PRINTS PR00175 Sodium/alanine symporter signature 409 431 1.9E-45 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:3.90.1100.10 406 552 5.2E-136 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:3.90.1100.10 20 149 5.2E-136 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:3.90.1100.10 622 675 5.2E-136 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF00562 RNA polymerase Rpb2, domain 6 681 1194 2.5E-153 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856:SF20 1 225 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856:SF20 301 688 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856:SF20 1018 1272 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856:SF20 709 896 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF10385 RNA polymerase beta subunit external 1 domain 552 619 2.4E-22 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.30.150.10 553 619 5.3E-20 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.40.50.150 793 903 9.0E-53 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.40.50.150 1029 1043 9.0E-53 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.40.50.100 678 758 7.8E-25 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:3.90.1110.10 151 226 4.4E-58 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:3.90.1110.10 307 405 4.4E-58 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF04565 RNA polymerase Rpb2, domain 3 474 542 5.2E-31 T 22-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 6 1269 0.0 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF04563 RNA polymerase beta subunit 25 460 1.2E-23 T 22-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1047 1059 - T 22-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 SUPERFAMILY SSF64484 9 222 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 SUPERFAMILY SSF64484 1023 1270 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 SUPERFAMILY SSF64484 304 905 0.0 T 22-04-2016 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856 1 225 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856 301 688 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856 1018 1272 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 PANTHER PTHR20856 709 896 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF04561 RNA polymerase Rpb2, domain 2 296 415 2.2E-21 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF04561 RNA polymerase Rpb2, domain 2 149 218 9.0E-7 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Pfam PF04560 RNA polymerase Rpb2, domain 7 1196 1271 1.1E-24 T 22-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 10 1272 11.914 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.40.270.10 1044 1172 8.9E-76 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS04885 f6a3142adeed531c034b362ee0aaaa40 1272 Gene3D G3DSA:2.40.270.10 759 786 8.9E-76 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.8E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 4.8E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.8E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 SUPERFAMILY SSF51735 2 239 3.08E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 Pfam PF00106 short chain dehydrogenase 3 201 3.2E-31 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PANTHER PTHR24320 3 235 7.9E-54 T 22-04-2016 MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.0E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MED134_RS00530 a6f13c9c252b633dfedf7da9c2e26c62 268 Gene3D G3DSA:3.40.50.720 2 238 2.2E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 Pfam PF13187 4Fe-4S dicluster domain 462 508 1.1E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 PANTHER PTHR30176 227 522 4.7E-12 T 22-04-2016 MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 SUPERFAMILY SSF54862 431 511 1.05E-12 T 22-04-2016 MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 463 474 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 494 505 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 Pfam PF12801 4Fe-4S binding domain 414 456 0.015 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 Pfam PF12801 4Fe-4S binding domain 316 355 6.4E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS06660 7bbd2e7b999a78a6fc6f9476ba99eaa7 543 Gene3D G3DSA:3.30.70.20 433 516 4.4E-13 T 22-04-2016 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 Pfam PF02421 Ferrous iron transport protein B 6 164 2.6E-51 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 11 678 5.3E-152 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 28 46 4.2E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 4.2E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 Pfam PF07670 Nucleoside recognition 345 434 3.8E-15 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 Pfam PF07670 Nucleoside recognition 512 682 2.5E-26 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 Gene3D G3DSA:3.40.50.300 3 170 5.9E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649:SF37 3 166 8.7E-211 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649:SF37 259 538 8.7E-211 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649:SF37 576 708 8.7E-211 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649 3 166 8.7E-211 T 22-04-2016 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649 259 538 8.7E-211 T 22-04-2016 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 PANTHER PTHR11649 576 708 8.7E-211 T 22-04-2016 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 Pfam PF07664 Ferrous iron transport protein B C terminus 454 506 2.8E-16 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MED134_RS10295 0bac957692aa63587ae1f17b0ac6e5ac 708 SUPERFAMILY SSF52540 5 169 1.09E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11910 f845056cef894befd62c9251e6c95292 226 Gene3D G3DSA:3.40.50.720 2 222 5.0E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11910 f845056cef894befd62c9251e6c95292 226 SUPERFAMILY SSF51735 2 223 2.37E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.3E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.3E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.3E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.3E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 2.3E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 Pfam PF00106 short chain dehydrogenase 2 187 3.9E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.1E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 1.1E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.1E-7 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PANTHER PTHR24322 145 176 2.7E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11910 f845056cef894befd62c9251e6c95292 226 PANTHER PTHR24322 6 126 2.7E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 Pfam PF13623 SurA N-terminal domain 4 137 1.5E-28 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 Pfam PF13616 PPIC-type PPIASE domain 336 462 4.9E-30 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 Pfam PF13145 PPIC-type PPIASE domain 213 332 1.0E-6 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 SUPERFAMILY SSF109998 207 250 3.53E-5 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 SUPERFAMILY SSF109998 43 172 3.53E-5 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657 345 600 4.5E-12 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657 1 171 4.5E-12 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657 305 315 4.5E-12 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 Gene3D G3DSA:3.10.50.40 591 680 1.7E-5 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 Gene3D G3DSA:3.10.50.40 346 459 3.6E-20 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 SUPERFAMILY SSF54534 346 462 1.77E-16 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657:SF11 345 600 4.5E-12 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657:SF11 1 171 4.5E-12 T 22-04-2016 MED134_RS06480 f2e5443229caef1f3686ee35e7a55d8a 713 PANTHER PTHR10657:SF11 305 315 4.5E-12 T 22-04-2016 MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 SMART SM00465 205 284 4.5E-13 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 Gene3D G3DSA:3.30.420.10 4 170 1.7E-49 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 SUPERFAMILY SSF53098 223 246 8.29E-56 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 SUPERFAMILY SSF53098 6 193 8.29E-56 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 11 166 1.5E-24 T 22-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 SUPERFAMILY SSF82771 206 280 3.27E-16 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 Pfam PF01541 GIY-YIG catalytic domain 207 276 6.4E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 Pfam PF00929 Exonuclease 11 164 1.3E-33 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 Gene3D G3DSA:3.40.1440.10 206 279 2.3E-6 T 22-04-2016 IPR027299 GIY-YIG domain MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 SMART SM00479 8 173 9.1E-40 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III MED134_RS01800 ff39a7b65f211b8bb0510ff1b9f437ab 466 PANTHER PTHR30231 4 172 4.1E-46 T 22-04-2016 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 Gene3D G3DSA:3.60.120.10 56 430 1.5E-118 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 PANTHER PTHR11236 80 430 5.5E-114 T 22-04-2016 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 PRINTS PR00095 Anthranilate synthase component I signature 361 375 6.1E-15 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 PRINTS PR00095 Anthranilate synthase component I signature 281 294 6.1E-15 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 PRINTS PR00095 Anthranilate synthase component I signature 376 390 6.1E-15 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 PRINTS PR00095 Anthranilate synthase component I signature 267 280 6.1E-15 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS04290 6493126fd94163b47dbee1940482826d 432 Pfam PF00425 chorismate binding enzyme 166 421 5.1E-84 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal MED134_RS04290 6493126fd94163b47dbee1940482826d 432 SUPERFAMILY SSF56322 12 430 3.53E-112 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 Gene3D G3DSA:1.20.1600.10 28 93 1.7E-35 T 22-04-2016 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 Gene3D G3DSA:1.20.1600.10 126 467 1.7E-35 T 22-04-2016 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 Pfam PF02321 Outer membrane efflux protein 36 246 1.5E-14 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 Pfam PF02321 Outer membrane efflux protein 291 466 5.5E-12 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 PANTHER PTHR30203 34 467 7.1E-28 T 22-04-2016 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 SUPERFAMILY SSF56954 2 86 8.37E-47 T 22-04-2016 MED134_RS06345 0af2055bb3d91698076c9261abd2c4f5 468 SUPERFAMILY SSF56954 115 467 8.37E-47 T 22-04-2016 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 57 2.4E-14 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PANTHER PTHR21342:SF1 1 151 7.2E-62 T 22-04-2016 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PANTHER PTHR21342 1 151 7.2E-62 T 22-04-2016 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 SUPERFAMILY SSF52374 2 151 4.5E-39 T 22-04-2016 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 158 30.283 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 Gene3D G3DSA:3.40.50.620 1 151 3.7E-49 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 Pfam PF01467 Cytidylyltransferase-like 6 133 1.3E-14 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.5E-37 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.5E-37 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.5E-37 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.5E-37 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.5E-37 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS13010 f455f5ac6e21a3fc145ba681e722050a 165 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 150 2.4E-50 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 MED134_RS09625 9a9a20dfd0d9ccfbc32e1b4006fb5d83 210 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 29 201 2.1E-70 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MED134_RS09625 9a9a20dfd0d9ccfbc32e1b4006fb5d83 210 SUPERFAMILY SSF55729 3 209 7.42E-84 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09625 9a9a20dfd0d9ccfbc32e1b4006fb5d83 210 PANTHER PTHR30098 5 210 8.1E-68 T 22-04-2016 MED134_RS09625 9a9a20dfd0d9ccfbc32e1b4006fb5d83 210 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 210 82.389 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MED134_RS09625 9a9a20dfd0d9ccfbc32e1b4006fb5d83 210 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 32 209 2.0E-60 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 Gene3D G3DSA:1.10.10.10 176 273 1.4E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 SUPERFAMILY SSF46894 175 273 3.4E-20 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 Pfam PF00486 Transcriptional regulatory protein, C terminal 200 272 3.1E-18 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 PANTHER PTHR26402:SF50 164 273 6.7E-17 T 22-04-2016 MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 PANTHER PTHR26402 164 273 6.7E-17 T 22-04-2016 MED134_RS01565 7fa6b8a7ca0b027ca86f4e98b671de33 275 SMART SM00862 199 272 3.6E-19 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS00220 67279d2df5fb46073a300ce97aab8f97 192 PANTHER PTHR30221 12 164 2.3E-23 T 22-04-2016 MED134_RS00220 67279d2df5fb46073a300ce97aab8f97 192 Pfam PF00924 Mechanosensitive ion channel 55 164 4.1E-13 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS00220 67279d2df5fb46073a300ce97aab8f97 192 Gene3D G3DSA:2.30.30.60 114 164 8.6E-8 T 22-04-2016 MED134_RS00220 67279d2df5fb46073a300ce97aab8f97 192 SUPERFAMILY SSF50182 99 164 1.21E-10 T 22-04-2016 IPR010920 LSM domain MED134_RS00220 67279d2df5fb46073a300ce97aab8f97 192 PANTHER PTHR30221:SF8 12 164 2.3E-23 T 22-04-2016 MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 Gene3D G3DSA:2.170.130.10 130 209 8.8E-5 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 SUPERFAMILY SSF56935 730 920 1.14E-12 T 22-04-2016 MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 SUPERFAMILY SSF56935 371 658 1.14E-12 T 22-04-2016 MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 Gene3D G3DSA:2.60.40.1120 25 116 6.0E-10 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 SUPERFAMILY SSF49464 24 131 1.83E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 Pfam PF13620 Carboxypeptidase regulatory-like domain 24 105 4.5E-10 T 22-04-2016 MED134_RS07125 900cb0a6194c39d4464b8bef49aca070 921 SUPERFAMILY SSF56935 126 411 1.4E-14 T 22-04-2016 MED134_RS13060 6f95b4851e107b2a02fc8e40d117c2b2 190 SUPERFAMILY SSF101874 28 189 5.1E-31 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13060 6f95b4851e107b2a02fc8e40d117c2b2 190 Pfam PF04264 YceI-like domain 29 189 1.0E-24 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13060 6f95b4851e107b2a02fc8e40d117c2b2 190 SMART SM00867 26 189 4.8E-20 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS13060 6f95b4851e107b2a02fc8e40d117c2b2 190 Gene3D G3DSA:2.40.128.110 30 189 2.1E-32 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS03895 47ef0496153f813bf7703e4ea734e311 306 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 5 291 7.6E-77 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS03895 47ef0496153f813bf7703e4ea734e311 306 Pfam PF11751 Protein of unknown function (DUF3308) 17 289 3.7E-77 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS00830 803a6bce3a66357671f88e2732782117 170 SMART SM00935 9 165 1.4E-30 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS00830 803a6bce3a66357671f88e2732782117 170 SUPERFAMILY SSF111384 19 164 6.8E-22 T 22-04-2016 IPR024930 Skp domain MED134_RS00830 803a6bce3a66357671f88e2732782117 170 Pfam PF03938 Outer membrane protein (OmpH-like) 7 164 4.6E-31 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS00830 803a6bce3a66357671f88e2732782117 170 PANTHER PTHR35089 2 170 6.6E-22 T 22-04-2016 MED134_RS00830 803a6bce3a66357671f88e2732782117 170 Gene3D G3DSA:3.30.910.20 9 164 3.0E-20 T 22-04-2016 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 SUPERFAMILY SSF53067 1 105 1.68E-17 T 22-04-2016 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 SUPERFAMILY SSF53067 111 236 1.79E-32 T 22-04-2016 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 232 2.6E-40 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 PANTHER PTHR34265 1 238 7.3E-47 T 22-04-2016 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 Pfam PF03309 Type III pantothenate kinase 3 192 1.4E-44 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 240 21.533 T 22-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 MED134_RS06510 00e7b13e209e81b75edca80e1d93f39e 241 Gene3D G3DSA:3.30.420.40 81 240 3.3E-44 T 22-04-2016 MED134_RS08130 fca1ca5033177ea96046b9e83b99faa8 194 Pfam PF01914 MarC family integral membrane protein 6 193 1.2E-37 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS08130 fca1ca5033177ea96046b9e83b99faa8 194 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 187 3.1E-31 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS08130 fca1ca5033177ea96046b9e83b99faa8 194 PANTHER PTHR33508:SF1 1 194 1.6E-41 T 22-04-2016 MED134_RS08130 fca1ca5033177ea96046b9e83b99faa8 194 PANTHER PTHR33508 1 194 1.6E-41 T 22-04-2016 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SUPERFAMILY SSF50249 547 643 1.59E-133 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Gene3D G3DSA:2.40.50.140 646 729 1.1E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 PANTHER PTHR23355:SF9 84 730 7.9E-224 T 22-04-2016 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Pfam PF00773 RNB domain 258 600 1.2E-107 T 22-04-2016 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SMART SM00316 643 726 3.7E-4 T 22-04-2016 IPR022967 RNA-binding domain, S1 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Pfam PF00575 S1 RNA binding domain 644 724 6.9E-7 T 22-04-2016 IPR003029 S1 domain GO:0003676 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 75 726 7.8E-160 T 22-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 TIGRFAM TIGR02063 RNase_R: ribonuclease R 15 726 1.9E-218 T 22-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SMART SM00357 150 212 0.91 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SMART SM00357 83 142 0.0048 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 PANTHER PTHR23355 84 730 7.9E-224 T 22-04-2016 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SUPERFAMILY SSF50249 185 510 1.59E-133 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Hamap MF_01895 Ribonuclease R [rnr]. 35 726 51.607 T 22-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 ProSitePatterns PS01175 Ribonuclease II family signature. 568 592 - T 22-04-2016 IPR022966 Ribonuclease II/R, conserved site MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Pfam PF08206 Ribonuclease B OB domain 156 211 8.9E-6 T 22-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 Pfam PF08206 Ribonuclease B OB domain 84 141 1.1E-11 T 22-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SMART SM00955 258 601 5.4E-150 T 22-04-2016 MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SUPERFAMILY SSF50249 76 214 1.2E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09090 a44d0090ed652b101bafbdcc0674b4fc 734 SUPERFAMILY SSF50249 646 725 5.07E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01765 5957513700027d42356e964a82e7e171 417 PANTHER PTHR10742 7 413 5.5E-42 T 22-04-2016 MED134_RS01765 5957513700027d42356e964a82e7e171 417 SUPERFAMILY SSF51905 1 281 4.32E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01765 5957513700027d42356e964a82e7e171 417 SUPERFAMILY SSF51905 374 412 4.32E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01765 5957513700027d42356e964a82e7e171 417 Gene3D G3DSA:3.50.50.60 183 278 7.5E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01765 5957513700027d42356e964a82e7e171 417 Gene3D G3DSA:3.50.50.60 3 94 7.5E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS01765 5957513700027d42356e964a82e7e171 417 Pfam PF01593 Flavin containing amine oxidoreductase 15 409 2.0E-31 T 22-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 MED134_RS01765 5957513700027d42356e964a82e7e171 417 PANTHER PTHR10742:SF287 7 413 5.5E-42 T 22-04-2016 MED134_RS13640 9edcd68981863eab54c9ce8ebc6f8eb8 310 SUPERFAMILY SSF53448 2 220 2.19E-52 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13640 9edcd68981863eab54c9ce8ebc6f8eb8 310 Gene3D G3DSA:3.90.550.10 2 219 6.6E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13640 9edcd68981863eab54c9ce8ebc6f8eb8 310 Pfam PF00535 Glycosyl transferase family 2 5 170 4.9E-32 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13640 9edcd68981863eab54c9ce8ebc6f8eb8 310 PANTHER PTHR22916 1 290 3.8E-44 T 22-04-2016 MED134_RS06895 250025c0168e84a8c5564a0a5233c1f8 603 Pfam PF00474 Sodium:solute symporter family 37 450 1.3E-34 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS06895 250025c0168e84a8c5564a0a5233c1f8 603 PANTHER PTHR11819 5 548 2.7E-185 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS06895 250025c0168e84a8c5564a0a5233c1f8 603 PANTHER PTHR11819:SF77 5 548 2.7E-185 T 22-04-2016 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 SMART SM00882 6 217 2.3E-79 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 PANTHER PTHR13707 1 233 5.6E-125 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 Pfam PF01144 Coenzyme A transferase 10 216 1.2E-71 T 22-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 SUPERFAMILY SSF100950 2 230 2.23E-82 T 22-04-2016 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 Gene3D G3DSA:3.40.1080.10 4 216 1.1E-93 T 22-04-2016 MED134_RS08775 37d539a494dfde89e994ac9532272964 233 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 1.2E-78 T 22-04-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 PANTHER PTHR34383 154 292 2.7E-106 T 22-04-2016 MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 PANTHER PTHR34383 30 138 2.7E-106 T 22-04-2016 MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 Gene3D G3DSA:3.40.50.300 8 291 3.8E-91 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 PIRSF PIRSF028756 3 292 4.6E-70 T 22-04-2016 IPR016898 Polyphosphate kinase 2 MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 29 267 5.8E-57 T 22-04-2016 IPR022488 Polyphosphate kinase-2-related MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 SUPERFAMILY SSF52540 60 265 2.15E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13235 57916f40d52dfc8c8a0c7d4abcc09878 292 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 15 279 4.5E-97 T 22-04-2016 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 SUPERFAMILY SSF56529 129 423 4.06E-98 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 PANTHER PTHR11820 7 96 1.0E-179 T 22-04-2016 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 PANTHER PTHR11820 127 425 1.0E-179 T 22-04-2016 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 133 420 2.0E-55 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 Gene3D G3DSA:2.30.30.230 12 129 3.2E-34 T 22-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 Gene3D G3DSA:3.90.850.10 130 417 3.6E-110 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 SUPERFAMILY SSF63433 11 127 9.02E-38 T 22-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 13 423 7.9E-171 T 22-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 Pfam PF09298 Fumarylacetoacetase N-terminal 25 127 1.2E-25 T 22-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 PANTHER PTHR11820:SF1 7 96 1.0E-179 T 22-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS00805 a5caa68a3b933773d924487146c6f9b1 430 PANTHER PTHR11820:SF1 127 425 1.0E-179 T 22-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 MED134_RS02825 b55df4b308627ff47b7e153cd6fa3209 251 Gene3D G3DSA:2.50.20.10 17 246 7.0E-10 T 22-04-2016 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PANTHER PTHR10264 4 319 4.3E-110 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 SMART SM00244 19 178 9.5E-33 T 22-04-2016 IPR001107 Band 7 domain MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PRINTS PR00721 Stomatin signature 130 153 2.8E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PRINTS PR00721 Stomatin signature 73 94 2.8E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PRINTS PR00721 Stomatin signature 26 48 2.8E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PRINTS PR00721 Stomatin signature 173 194 2.8E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 Pfam PF01145 SPFH domain / Band 7 family 23 194 3.4E-30 T 22-04-2016 IPR001107 Band 7 domain MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 PANTHER PTHR10264:SF84 4 319 4.3E-110 T 22-04-2016 MED134_RS09145 381a70c551512ec3d769616c50ef8728 319 SUPERFAMILY SSF117892 50 184 2.09E-25 T 22-04-2016 IPR001107 Band 7 domain MED134_RS06970 9f9f537fbd9f4701ca9bc79e92bba3ec 254 Gene3D G3DSA:3.40.50.150 125 232 8.9E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS06970 9f9f537fbd9f4701ca9bc79e92bba3ec 254 PANTHER PTHR10108 125 241 3.7E-19 T 22-04-2016 MED134_RS06970 9f9f537fbd9f4701ca9bc79e92bba3ec 254 Pfam PF08241 Methyltransferase domain 118 172 1.0E-15 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MED134_RS06970 9f9f537fbd9f4701ca9bc79e92bba3ec 254 SUPERFAMILY SSF53335 124 238 6.97E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS04755 e6ece89a16ca3474eb2822bf2a0e4fec 285 Pfam PF02626 Allophanate hydrolase subunit 2 27 280 1.8E-59 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B MED134_RS04755 e6ece89a16ca3474eb2822bf2a0e4fec 285 SMART SM00797 26 285 1.3E-43 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B MED134_RS06815 61243b25922016c4a4e01a6e90466860 230 PANTHER PTHR11311:SF15 40 197 1.2E-22 T 22-04-2016 MED134_RS06815 61243b25922016c4a4e01a6e90466860 230 Pfam PF06468 Spondin_N 40 201 1.0E-29 T 22-04-2016 IPR009465 Spondin, N-terminal MED134_RS06815 61243b25922016c4a4e01a6e90466860 230 PANTHER PTHR11311 40 197 1.2E-22 T 22-04-2016 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 SUPERFAMILY SSF88946 4 100 4.71E-20 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 Pfam PF08281 Sigma-70, region 4 129 180 7.2E-12 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 SUPERFAMILY SSF88659 116 185 7.66E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 181 9.8E-28 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 Gene3D G3DSA:1.10.1740.10 12 105 2.3E-23 T 22-04-2016 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 PANTHER PTHR30173 12 186 2.2E-36 T 22-04-2016 MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 Gene3D G3DSA:1.10.10.10 122 186 2.7E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05785 848f73c02904f2f4971af7c2b6e8a660 189 Pfam PF04542 Sigma-70 region 2 33 92 4.1E-8 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 Gene3D G3DSA:3.40.47.10 264 422 2.2E-28 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 Gene3D G3DSA:3.40.47.10 2 262 3.3E-41 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 374 9.1E-21 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 SMART SM00825 Beta-ketoacyl synthase 5 424 4.1E-9 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 251 2.3E-28 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 SUPERFAMILY SSF53901 4 258 3.01E-43 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 PANTHER PTHR11712 4 421 5.5E-61 T 22-04-2016 MED134_RS02620 930ecd8b26e18e30f82e1398c82ebcd5 426 SUPERFAMILY SSF53901 219 421 4.76E-45 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 PANTHER PTHR11609:SF7 3 365 9.9E-198 T 22-04-2016 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 Pfam PF02222 ATP-grasp domain 113 284 5.5E-55 T 22-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 1 387 48.516 T 22-04-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 Gene3D G3DSA:3.40.50.20 2 110 4.6E-34 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 Gene3D G3DSA:3.30.470.20 189 384 1.2E-63 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 SUPERFAMILY SSF52440 3 102 1.58E-29 T 22-04-2016 IPR016185 Pre-ATP-grasp domain MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 SUPERFAMILY SSF51246 313 385 2.67E-12 T 22-04-2016 IPR011054 Rudiment single hybrid motif MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 Gene3D G3DSA:3.30.1490.20 114 188 3.3E-24 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 4 385 4.5E-156 T 22-04-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 PANTHER PTHR11609 3 365 9.9E-198 T 22-04-2016 MED134_RS12405 5e6669fc825c504ecddab7d2c3b1fd61 387 SUPERFAMILY SSF56059 104 307 1.4E-57 T 22-04-2016 MED134_RS12570 fac18afb8f5f3f4f96627982856aa577 137 PANTHER PTHR30574 4 130 1.1E-36 T 22-04-2016 MED134_RS12570 fac18afb8f5f3f4f96627982856aa577 137 Pfam PF04143 Sulphur transport 29 129 6.2E-11 T 22-04-2016 IPR007272 Sulphur transport domain MED134_RS12570 fac18afb8f5f3f4f96627982856aa577 137 PANTHER PTHR30574:SF7 4 130 1.1E-36 T 22-04-2016 MED134_RS09975 86fbbc1936b56dfee8f74b80ffa4db66 378 Pfam PF04326 Putative DNA-binding domain 17 142 7.5E-11 T 22-04-2016 IPR007421 Schlafen, AAA domain GO:0005524 MED134_RS14710 31275a2e8bff308ce57d7e7d9fed8534 206 PANTHER PTHR31462 5 193 3.4E-12 T 22-04-2016 MED134_RS14710 31275a2e8bff308ce57d7e7d9fed8534 206 Pfam PF06736 Protein of unknown function (DUF1211) 10 100 1.2E-21 T 22-04-2016 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 MED134_RS10625 49a6808977c002af1420a9897f6363d2 296 Pfam PF06445 GyrI-like small molecule binding domain 200 294 1.5E-6 T 22-04-2016 IPR029442 GyrI-like small molecule binding domain MED134_RS10625 49a6808977c002af1420a9897f6363d2 296 SMART SM00871 141 295 3.7E-5 T 22-04-2016 IPR010499 Bacterial transcription activator, effector binding MED134_RS10625 49a6808977c002af1420a9897f6363d2 296 Gene3D G3DSA:3.20.80.10 203 294 8.3E-4 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS10625 49a6808977c002af1420a9897f6363d2 296 SUPERFAMILY SSF55136 173 294 5.75E-8 T 22-04-2016 IPR011256 Regulatory factor, effector binding domain MED134_RS07535 23f9cecad55f226e198f236579790e22 334 SUPERFAMILY SSF111384 27 172 7.06E-21 T 22-04-2016 IPR024930 Skp domain MED134_RS07535 23f9cecad55f226e198f236579790e22 334 Gene3D G3DSA:3.30.910.20 18 173 1.2E-17 T 22-04-2016 MED134_RS07535 23f9cecad55f226e198f236579790e22 334 Pfam PF03938 Outer membrane protein (OmpH-like) 11 171 1.7E-30 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS07535 23f9cecad55f226e198f236579790e22 334 SMART SM00935 14 174 8.8E-38 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS07535 23f9cecad55f226e198f236579790e22 334 PANTHER PTHR35089 7 180 6.2E-29 T 22-04-2016 MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 SUPERFAMILY SSF51395 8 487 1.1E-120 T 22-04-2016 MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 PIRSF PIRSF006429 2 529 5.4E-142 T 22-04-2016 IPR024188 Glutamate synthase large subunit-like protein MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 PANTHER PTHR11938 150 478 1.7E-62 T 22-04-2016 MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 Gene3D G3DSA:3.20.20.70 30 478 4.1E-113 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 PANTHER PTHR11938:SF50 150 478 1.7E-62 T 22-04-2016 MED134_RS03050 beea0667d8f2303460311da2b891a7ce 533 Pfam PF01645 Conserved region in glutamate synthase 147 464 7.3E-80 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MED134_RS13400 f1d641882dbbf828049b2843c28fd40b 355 PANTHER PTHR22916 5 200 6.9E-16 T 22-04-2016 MED134_RS13400 f1d641882dbbf828049b2843c28fd40b 355 SUPERFAMILY SSF53448 4 211 1.5E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13400 f1d641882dbbf828049b2843c28fd40b 355 Pfam PF00535 Glycosyl transferase family 2 6 122 4.3E-12 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13400 f1d641882dbbf828049b2843c28fd40b 355 Gene3D G3DSA:3.90.550.10 8 213 2.8E-28 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13400 f1d641882dbbf828049b2843c28fd40b 355 Pfam PF02709 N-terminal domain of galactosyltransferase 134 205 2.0E-13 T 22-04-2016 IPR027791 Galactosyltransferase, C-terminal UniPathway: UPA00378 MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 PANTHER PTHR30244:SF18 1 381 2.0E-121 T 22-04-2016 MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 PANTHER PTHR30244 1 381 2.0E-121 T 22-04-2016 MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 372 5.5E-88 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 PIRSF PIRSF000390 1 381 2.4E-94 T 22-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 SUPERFAMILY SSF53383 11 378 4.5E-94 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 Gene3D G3DSA:3.90.1150.10 253 379 3.1E-42 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS01430 a7f146f22e975af222d60f826297e6bb 381 Gene3D G3DSA:3.40.640.10 6 251 7.7E-92 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SUPERFAMILY SSF48452 466 572 5.06E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SMART SM00028 19 53 16.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SMART SM00028 376 409 27.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SMART SM00028 507 540 47.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SMART SM00028 54 87 180.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 PANTHER PTHR23083 25 184 7.5E-13 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 PANTHER PTHR23083 233 298 7.5E-13 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 PANTHER PTHR23083 512 572 7.5E-13 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 PANTHER PTHR23083 339 414 7.5E-13 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 PANTHER PTHR23083 203 214 7.5E-13 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Pfam PF13176 Tetratricopeptide repeat 25 50 0.027 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Gene3D G3DSA:1.25.40.10 472 572 2.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Gene3D G3DSA:1.25.40.10 349 429 2.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Gene3D G3DSA:1.25.40.10 25 282 3.4E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 SUPERFAMILY SSF48452 24 194 1.99E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Pfam PF13432 Tetratricopeptide repeat 474 527 0.012 T 22-04-2016 MED134_RS08275 dc9590071336492c57e5ca8444d8f8f2 597 Pfam PF13174 Tetratricopeptide repeat 545 572 0.017 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS14465 361cbeecca5b4f2dd31137a3c8f71319 136 Pfam PF14126 Domain of unknown function (DUF4293) 2 135 2.6E-24 T 22-04-2016 IPR025635 Protein of unknown function DUF4293 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 PANTHER PTHR23088:SF5 1 309 5.0E-65 T 22-04-2016 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 PANTHER PTHR23088 1 309 5.0E-65 T 22-04-2016 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 168 181 - T 22-04-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 Gene3D G3DSA:3.60.110.10 6 308 1.5E-58 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 SUPERFAMILY SSF56317 5 309 1.44E-64 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS11065 42bdd97e04441abe9fe4c966987429c8 319 Pfam PF00795 Carbon-nitrogen hydrolase 8 286 1.6E-40 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 PANTHER PTHR22572 166 372 1.1E-31 T 22-04-2016 MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 SUPERFAMILY SSF51161 178 353 3.96E-17 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 TIGRFAM TIGR03991 alt_bact_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 382 1.7E-140 T 22-04-2016 IPR023917 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, bacterial-type MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 Pfam PF13562 Sugar nucleotidyl transferase 3 151 2.4E-49 T 22-04-2016 IPR023917 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, bacterial-type MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 Gene3D G3DSA:2.160.10.10 167 328 5.1E-13 T 22-04-2016 MED134_RS05285 b9f133ec6bb9f36a366177ce0b187f61 391 PANTHER PTHR22572:SF99 166 372 1.1E-31 T 22-04-2016 MED134_RS09120 b4cd51af3f1b431328a06a8bd67f74f1 69 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 7 68 6.9E-27 T 22-04-2016 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon MED134_RS09120 b4cd51af3f1b431328a06a8bd67f74f1 69 Gene3D G3DSA:2.20.28.30 4 60 8.1E-4 T 22-04-2016 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 PANTHER PTHR13693:SF60 1 397 2.6E-268 T 22-04-2016 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 397 3.1E-213 T 22-04-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 SUPERFAMILY SSF53383 5 395 9.87E-123 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 PANTHER PTHR13693 1 397 2.6E-268 T 22-04-2016 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 Gene3D G3DSA:3.40.640.10 60 278 5.0E-88 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 395 54.567 T 22-04-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 Gene3D G3DSA:3.90.1150.10 279 392 6.9E-34 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS08990 d564af95ddca64b216c3115abcb2cde9 397 Pfam PF00155 Aminotransferase class I and II 43 386 4.5E-75 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS14730 4e9bbd4e0500ff3c1c525329d695db52 985 Pfam PF07705 CARDB 657 732 9.5E-5 T 22-04-2016 IPR011635 CARDB domain MED134_RS14730 4e9bbd4e0500ff3c1c525329d695db52 985 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 914 985 3.1E-7 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 Pfam PF10442 FIST C domain 218 355 2.8E-30 T 22-04-2016 IPR019494 FIST, C-domain MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 SMART SM01204 218 356 5.2E-40 T 22-04-2016 IPR019494 FIST, C-domain MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 SMART SM00897 24 217 1.0E-41 T 22-04-2016 IPR013702 FIST domain, N-terminal MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 Pfam PF08495 FIST N domain 27 216 8.2E-32 T 22-04-2016 IPR013702 FIST domain, N-terminal MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 PANTHER PTHR40252 1 376 4.2E-63 T 22-04-2016 MED134_RS00605 302bb855fbd86058fbc66ad725d94eb4 376 PANTHER PTHR40252:SF1 1 376 4.2E-63 T 22-04-2016 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 Gene3D G3DSA:3.40.640.10 54 297 7.4E-74 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 Pfam PF00202 Aminotransferase class-III 15 387 4.1E-92 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 Gene3D G3DSA:3.90.1150.10 18 53 7.9E-23 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 Gene3D G3DSA:3.90.1150.10 300 390 7.9E-23 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 SUPERFAMILY SSF53383 9 389 2.53E-105 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 PANTHER PTHR11986 15 396 3.9E-118 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS03280 7d729f253b0d15c5ab7330813216e488 399 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 213 250 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS13680 4635e91ca635cceaa81dc86010c87bc4 80 PANTHER PTHR40613 4 73 7.2E-27 T 22-04-2016 MED134_RS13680 4635e91ca635cceaa81dc86010c87bc4 80 PANTHER PTHR40613:SF1 4 73 7.2E-27 T 22-04-2016 MED134_RS13680 4635e91ca635cceaa81dc86010c87bc4 80 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 5 69 1.3E-31 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor MED134_RS13680 4635e91ca635cceaa81dc86010c87bc4 80 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 16 63 4.0E-14 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 SUPERFAMILY SSF54637 2 138 3.6E-28 T 22-04-2016 IPR029069 HotDog domain MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 133 2.3E-33 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 PANTHER PTHR12418 17 136 1.2E-41 T 22-04-2016 MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 Gene3D G3DSA:3.10.129.10 5 138 5.2E-43 T 22-04-2016 IPR029069 HotDog domain MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 PANTHER PTHR12418:SF33 17 136 1.2E-41 T 22-04-2016 MED134_RS13750 5913ce4313b57821e9add3b2e50fbb19 139 Pfam PF03061 Thioesterase superfamily 51 126 8.3E-11 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS02770 07bf4c133bc50edfd6cb13a461e7b6f1 240 PANTHER PTHR38480:SF1 1 237 3.0E-42 T 22-04-2016 MED134_RS02770 07bf4c133bc50edfd6cb13a461e7b6f1 240 PANTHER PTHR38480 1 237 3.0E-42 T 22-04-2016 MED134_RS02770 07bf4c133bc50edfd6cb13a461e7b6f1 240 Pfam PF06271 RDD family 18 146 2.9E-23 T 22-04-2016 IPR010432 RDD MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 PANTHER PTHR21091:SF111 11 328 3.5E-174 T 22-04-2016 MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 SUPERFAMILY SSF82282 3 329 1.1E-100 T 22-04-2016 IPR003726 Homocysteine-binding domain MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 Gene3D G3DSA:3.20.20.330 2 329 1.2E-114 T 22-04-2016 IPR003726 Homocysteine-binding domain MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 PANTHER PTHR21091 11 328 3.5E-174 T 22-04-2016 MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 PIRSF PIRSF037505 53 329 1.8E-10 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 MED134_RS07090 9322d4bd493cb9e51f304c45a4be9204 332 Pfam PF02574 Homocysteine S-methyltransferase 14 321 2.4E-93 T 22-04-2016 IPR003726 Homocysteine-binding domain MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 4 143 1.0E-19 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 SUPERFAMILY SSF89447 3 143 2.93E-40 T 22-04-2016 MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 156 38.724 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 4 146 4.1E-31 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 PANTHER PTHR34701 4 154 6.1E-39 T 22-04-2016 MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 Pfam PF02381 MraZ protein, putative antitoxin-like 5 75 3.9E-12 T 22-04-2016 IPR020603 MraZ domain MED134_RS12490 413d3da86553d246c8dbfce0335dd311 156 Pfam PF02381 MraZ protein, putative antitoxin-like 84 144 1.3E-11 T 22-04-2016 IPR020603 MraZ domain MED134_RS14635 40f739a268e0ce6b9abe0c3832ba19e2 228 Pfam PF00691 OmpA family 142 220 2.2E-14 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14635 40f739a268e0ce6b9abe0c3832ba19e2 228 SUPERFAMILY SSF103088 125 227 5.23E-22 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS14635 40f739a268e0ce6b9abe0c3832ba19e2 228 PANTHER PTHR30128 142 227 4.7E-18 T 22-04-2016 MED134_RS14635 40f739a268e0ce6b9abe0c3832ba19e2 228 Gene3D G3DSA:3.30.1330.60 133 227 7.6E-22 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 PANTHER PTHR34182 5 110 2.7E-14 T 22-04-2016 MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 74 2.6E-20 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 2.4E-7 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 2.4E-7 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 2.4E-7 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MED134_RS06145 163d2125efacde6577e56d91d59cb144 114 Pfam PF03840 Preprotein translocase SecG subunit 7 75 1.0E-18 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MED134_RS08435 a22a405763cc17afa9cfa00d6be3de02 87 Pfam PF12728 Helix-turn-helix domain 21 68 1.1E-14 T 22-04-2016 MED134_RS08435 a22a405763cc17afa9cfa00d6be3de02 87 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 22 65 4.9E-14 T 22-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 MED134_RS08435 a22a405763cc17afa9cfa00d6be3de02 87 Gene3D G3DSA:1.10.10.10 23 71 4.3E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08435 a22a405763cc17afa9cfa00d6be3de02 87 SUPERFAMILY SSF46955 20 68 3.48E-6 T 22-04-2016 IPR009061 Putative DNA-binding domain MED134_RS08715 dd29ee33641f3e90bc54ecac497907b3 149 Gene3D G3DSA:3.30.70.900 17 100 2.4E-4 T 22-04-2016 MED134_RS08715 dd29ee33641f3e90bc54ecac497907b3 149 Pfam PF11695 Domain of unknown function (DUF3291) 5 143 2.9E-52 T 22-04-2016 IPR021708 Domain of unknown function DUF3291 MED134_RS08715 dd29ee33641f3e90bc54ecac497907b3 149 SUPERFAMILY SSF54909 19 118 1.48E-13 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 394 3.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 340 3.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 354 3.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 373 3.1E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 SUPERFAMILY SSF55874 248 393 1.57E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 395 3.1E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 Gene3D G3DSA:1.10.287.130 193 241 3.6E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PANTHER PTHR24423 196 396 3.0E-38 T 22-04-2016 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 PANTHER PTHR24423 11 53 3.0E-38 T 22-04-2016 MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 Gene3D G3DSA:3.30.565.10 251 393 1.4E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 SMART SM00387 289 396 1.1E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS09985 a3085f50784a34c1f7afa9e297c5df77 396 SUPERFAMILY SSF47384 175 241 3.34E-5 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 7.7E-41 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 7.7E-41 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.7E-41 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 7.7E-41 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 7.7E-41 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 SUPERFAMILY SSF55424 342 459 7.56E-41 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 4.6E-77 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PIRSF PIRSF000350 1 463 3.3E-97 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 Gene3D G3DSA:3.50.50.60 139 333 2.5E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PANTHER PTHR22912 3 458 2.4E-224 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 Gene3D G3DSA:3.50.50.60 2 138 2.2E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 PANTHER PTHR22912:SF151 3 458 2.4E-224 T 22-04-2016 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 465 5.4E-175 T 22-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 455 6.5E-37 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 SUPERFAMILY SSF51905 3 335 6.02E-70 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 327 2.6E-74 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14090 dbb0d6104ada1a910ce3a53ca60bf2f1 466 Gene3D G3DSA:3.30.390.30 334 460 5.7E-47 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 PANTHER PTHR19211:SF7 1 563 0.0 T 22-04-2016 MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Pfam PF12848 ABC transporter 239 313 2.2E-11 T 22-04-2016 IPR032781 ABC-transporter extension domain MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 PANTHER PTHR19211 1 563 0.0 T 22-04-2016 MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 SUPERFAMILY SSF52540 332 531 2.74E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Pfam PF00005 ABC transporter 26 200 3.0E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Pfam PF00005 ABC transporter 349 482 2.8E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 SUPERFAMILY SSF52540 11 245 2.1E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Gene3D G3DSA:3.40.50.300 10 113 2.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Gene3D G3DSA:3.40.50.300 146 297 2.2E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 SMART SM00382 357 535 9.9E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 SMART SM00382 35 245 3.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 6 561 1.6E-275 T 22-04-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 Gene3D G3DSA:3.40.50.300 331 545 2.1E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04285 33b50386da47e498f17f5d9bcdb59dd8 563 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Gene3D G3DSA:2.40.50.140 407 529 3.5E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Gene3D G3DSA:3.30.470.30 231 345 3.9E-25 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Gene3D G3DSA:3.30.1490.70 359 402 6.6E-19 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Gene3D G3DSA:3.30.1490.70 197 230 6.6E-19 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 SUPERFAMILY SSF56091 200 402 3.45E-50 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Pfam PF01068 ATP dependent DNA ligase domain 219 402 3.0E-29 T 22-04-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 PANTHER PTHR10459 105 528 6.4E-69 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 SUPERFAMILY SSF117018 3 178 8.5E-9 T 22-04-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 3 529 5.6E-192 T 22-04-2016 IPR026333 ATP-dependent DNA ligase, PP_1105 family MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Pfam PF04679 ATP dependent DNA ligase C terminal region 423 514 4.0E-10 T 22-04-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 PANTHER PTHR10459:SF10 105 528 6.4E-69 T 22-04-2016 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 Pfam PF04675 DNA ligase N terminus 3 159 1.6E-18 T 22-04-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 MED134_RS08465 67af77b09919c4a32c48cbc3dbf90204 531 SUPERFAMILY SSF50249 407 529 2.4E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS14535 e647b46d786692104eb634d637277146 160 Gene3D G3DSA:1.10.10.10 2 55 2.6E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS14535 e647b46d786692104eb634d637277146 160 SUPERFAMILY SSF54909 68 146 3.89E-14 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS14535 e647b46d786692104eb634d637277146 160 Pfam PF01037 Lrp/AsnC ligand binding domain 74 143 8.1E-12 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS14535 e647b46d786692104eb634d637277146 160 SMART SM00344 6 113 1.2E-31 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MED134_RS14535 e647b46d786692104eb634d637277146 160 PANTHER PTHR30154:SF2 1 155 1.0E-40 T 22-04-2016 MED134_RS14535 e647b46d786692104eb634d637277146 160 SUPERFAMILY SSF46785 5 66 2.14E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS14535 e647b46d786692104eb634d637277146 160 PANTHER PTHR30154 1 155 1.0E-40 T 22-04-2016 MED134_RS14535 e647b46d786692104eb634d637277146 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.9E-10 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS14535 e647b46d786692104eb634d637277146 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.9E-10 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS14535 e647b46d786692104eb634d637277146 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.9E-10 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS14535 e647b46d786692104eb634d637277146 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 4.6E-14 T 22-04-2016 MED134_RS14535 e647b46d786692104eb634d637277146 160 Gene3D G3DSA:3.30.70.920 59 147 8.0E-17 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 Pfam PF05193 Peptidase M16 inactive domain 197 376 1.0E-25 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 PANTHER PTHR11851 6 453 5.5E-56 T 22-04-2016 MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 Gene3D G3DSA:3.30.830.10 28 251 7.2E-38 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 SUPERFAMILY SSF63411 22 246 1.34E-42 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 SUPERFAMILY SSF63411 264 453 1.65E-37 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 Gene3D G3DSA:3.30.830.10 262 443 5.9E-30 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS01280 0a8f97399d5f6e1911e4b0cd150931f1 689 PANTHER PTHR11851:SF140 6 453 5.5E-56 T 22-04-2016 MED134_RS12930 f95f4cb6aca273424a52b0925a743fe2 209 SUPERFAMILY SSF56925 19 205 2.28E-9 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS12930 f95f4cb6aca273424a52b0925a743fe2 209 Pfam PF13568 Outer membrane protein beta-barrel domain 21 172 5.7E-14 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS05590 5167e1529e9697f49577283500009286 150 SUPERFAMILY SSF69500 1 146 1.1E-54 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain MED134_RS05590 5167e1529e9697f49577283500009286 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 145 2.2E-54 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 MED134_RS05590 5167e1529e9697f49577283500009286 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 146 34.193 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 MED134_RS05590 5167e1529e9697f49577283500009286 150 PANTHER PTHR10472 2 149 6.7E-71 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 MED134_RS05590 5167e1529e9697f49577283500009286 150 Gene3D G3DSA:3.50.80.10 1 146 1.9E-58 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain MED134_RS05590 5167e1529e9697f49577283500009286 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 4.2E-58 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Pfam PF00117 Glutamine amidotransferase class-I 7 186 5.4E-31 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Gene3D G3DSA:3.30.300.10 386 510 6.0E-53 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Gene3D G3DSA:3.40.50.620 210 380 2.2E-50 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Pfam PF00958 GMP synthase C terminal domain 420 509 2.6E-43 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.8E-5 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 163 176 1.8E-5 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.8E-5 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 189 5.4E-60 T 22-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 SUPERFAMILY SSF52317 4 194 7.7E-46 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Pfam PF02540 NAD synthase 209 276 3.9E-7 T 22-04-2016 IPR022310 NAD/GMP synthase MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Gene3D G3DSA:3.40.50.880 3 209 1.6E-53 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 SUPERFAMILY SSF52402 179 431 8.82E-49 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 PANTHER PTHR11922 1 507 5.9E-258 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 199 510 1.8E-137 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 PANTHER PTHR11922:SF2 1 507 5.9E-258 T 22-04-2016 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 510 49.888 T 22-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 MED134_RS03410 3d63b9327cbd0e38f13138a1a0638b7b 510 SUPERFAMILY SSF54810 390 510 1.22E-50 T 22-04-2016 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 Gene3D G3DSA:2.170.130.10 114 222 3.5E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 Pfam PF07715 TonB-dependent Receptor Plug Domain 119 215 2.6E-7 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 SUPERFAMILY SSF49464 24 110 3.01E-12 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 Pfam PF13715 CarboxypepD_reg-like domain 25 108 9.2E-10 T 22-04-2016 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 Gene3D G3DSA:2.40.170.20 248 822 7.0E-21 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 Gene3D G3DSA:2.60.40.1120 24 113 1.2E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 PANTHER PTHR11532:SF57 2 152 1.3E-14 T 22-04-2016 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 PANTHER PTHR11532 2 152 1.3E-14 T 22-04-2016 MED134_RS13905 68e66b1e507f3374b734e7955362c523 822 SUPERFAMILY SSF56935 112 822 4.12E-56 T 22-04-2016 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 PANTHER PTHR10744 7 84 1.6E-33 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 1 83 24.333 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 Gene3D G3DSA:2.40.50.140 7 84 9.0E-33 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 12 78 9.0E-23 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 7.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 7.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 7.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 Pfam PF00366 Ribosomal protein S17 12 79 2.2E-29 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.7E-32 T 22-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12280 d42757f0c74880a45603cfe2caf02d16 85 SUPERFAMILY SSF50249 7 84 4.71E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS04950 40071e7c6b6ecf56c74db1fec6acf28e 101 Gene3D G3DSA:3.30.160.100 1 98 1.9E-19 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS04950 40071e7c6b6ecf56c74db1fec6acf28e 101 SUPERFAMILY SSF69754 1 93 2.75E-19 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS04950 40071e7c6b6ecf56c74db1fec6acf28e 101 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 3.0E-12 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 Pfam PF00425 chorismate binding enzyme 201 451 2.0E-78 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PANTHER PTHR11236:SF9 4 465 7.0E-157 T 22-04-2016 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PANTHER PTHR11236 4 465 7.0E-157 T 22-04-2016 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 SUPERFAMILY SSF56322 4 462 5.49E-129 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PRINTS PR00095 Anthranilate synthase component I signature 315 328 3.0E-14 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PRINTS PR00095 Anthranilate synthase component I signature 301 314 3.0E-14 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PRINTS PR00095 Anthranilate synthase component I signature 408 422 3.0E-14 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 PRINTS PR00095 Anthranilate synthase component I signature 393 407 3.0E-14 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 Pfam PF04715 Anthranilate synthase component I, N terminal region 15 160 2.9E-28 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 MED134_RS13055 f7dcccf198874182b6743f3ac35d156c 465 Gene3D G3DSA:3.60.120.10 3 464 9.7E-135 T 22-04-2016 IPR005801 ADC synthase GO:0009058 MED134_RS00140 1a36920d149c8ca30fea8f9f07272c23 215 PANTHER PTHR12992 46 205 3.0E-30 T 22-04-2016 MED134_RS00140 1a36920d149c8ca30fea8f9f07272c23 215 Pfam PF00293 NUDIX domain 58 166 1.5E-11 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 MED134_RS00140 1a36920d149c8ca30fea8f9f07272c23 215 Gene3D G3DSA:3.90.79.10 35 208 7.6E-27 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS00140 1a36920d149c8ca30fea8f9f07272c23 215 SUPERFAMILY SSF55811 45 202 6.63E-28 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 SUPERFAMILY SSF46767 68 149 1.44E-30 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 119 125 - T 22-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 SUPERFAMILY SSF53155 2 74 2.35E-18 T 22-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 Gene3D G3DSA:1.10.10.10 67 149 2.3E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 PANTHER PTHR10815:SF5 1 148 6.3E-52 T 22-04-2016 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 69 148 1.9E-34 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 PANTHER PTHR10815 1 148 6.3E-52 T 22-04-2016 MED134_RS08730 0a00ad83f4f623a61c13b8d1e9872b32 157 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 71 148 5.9E-32 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS13840 3d7c12790f9b9523b7e41952ef259be4 142 Pfam PF14088 Domain of unknown function (DUF4268) 11 136 1.2E-24 T 22-04-2016 IPR025364 Domain of unknown function DUF4268 MED134_RS14755 69df6847f4b6c2e4afb62e1fdd53b11a 424 Pfam PF02018 Carbohydrate binding domain 20 141 5.0E-8 T 22-04-2016 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 MED134_RS14755 69df6847f4b6c2e4afb62e1fdd53b11a 424 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 355 424 2.6E-15 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS14755 69df6847f4b6c2e4afb62e1fdd53b11a 424 Gene3D G3DSA:2.60.120.260 19 163 2.0E-21 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS14755 69df6847f4b6c2e4afb62e1fdd53b11a 424 SUPERFAMILY SSF49785 20 157 5.61E-24 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS14755 69df6847f4b6c2e4afb62e1fdd53b11a 424 Gene3D G3DSA:2.60.120.360 212 338 1.5E-4 T 22-04-2016 MED134_RS02325 3ee138703a0e7d258e60bf386660c9c9 197 Gene3D G3DSA:2.30.180.10 48 194 4.2E-36 T 22-04-2016 IPR000782 FAS1 domain MED134_RS02325 3ee138703a0e7d258e60bf386660c9c9 197 SUPERFAMILY SSF82153 49 195 7.98E-39 T 22-04-2016 IPR000782 FAS1 domain MED134_RS02325 3ee138703a0e7d258e60bf386660c9c9 197 Pfam PF02469 Fasciclin domain 60 194 6.0E-31 T 22-04-2016 IPR000782 FAS1 domain MED134_RS02325 3ee138703a0e7d258e60bf386660c9c9 197 SMART SM00554 84 195 3.1E-23 T 22-04-2016 IPR000782 FAS1 domain MED134_RS02325 3ee138703a0e7d258e60bf386660c9c9 197 PANTHER PTHR10900 49 194 1.1E-44 T 22-04-2016 MED134_RS06595 156a113c162575bbf5a5a6fac86c5ec9 266 PANTHER PTHR23054:SF14 58 264 7.3E-20 T 22-04-2016 MED134_RS06595 156a113c162575bbf5a5a6fac86c5ec9 266 Pfam PF04784 Protein of unknown function, DUF547 98 203 1.2E-25 T 22-04-2016 IPR006869 Domain of unknown function DUF547 MED134_RS06595 156a113c162575bbf5a5a6fac86c5ec9 266 PANTHER PTHR23054 58 264 7.3E-20 T 22-04-2016 MED134_RS14305 4b4bc49d0d46be34fe35cce8aaac06a9 1240 Pfam PF00149 Calcineurin-like phosphoesterase 49 246 2.5E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS14305 4b4bc49d0d46be34fe35cce8aaac06a9 1240 SUPERFAMILY SSF56300 49 251 1.98E-41 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14305 4b4bc49d0d46be34fe35cce8aaac06a9 1240 SUPERFAMILY SSF56300 294 367 1.98E-41 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14305 4b4bc49d0d46be34fe35cce8aaac06a9 1240 Gene3D G3DSA:3.60.21.10 49 251 4.4E-43 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14305 4b4bc49d0d46be34fe35cce8aaac06a9 1240 Gene3D G3DSA:3.60.21.10 294 383 4.4E-43 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14760 74cb1aae4527bc3d03a1041420f230b0 267 Pfam PF12412 Protein of unknown function (DUF3667) 44 87 5.1E-18 T 22-04-2016 IPR022134 Protein of unknown function DUF3667 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Gene3D G3DSA:3.20.70.20 388 545 3.9E-69 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Gene3D G3DSA:3.20.70.20 142 338 3.9E-69 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Gene3D G3DSA:3.20.70.20 593 638 3.9E-69 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Gene3D G3DSA:3.20.70.20 699 710 3.9E-69 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PANTHER PTHR11573 848 874 0.0 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PANTHER PTHR11573 2 769 0.0 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 582 604 - T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 SUPERFAMILY SSF51998 214 643 4.27E-189 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 SUPERFAMILY SSF51998 676 751 4.27E-189 T 22-04-2016 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Pfam PF03477 ATP cone domain 1 88 6.3E-18 T 22-04-2016 IPR005144 ATP-cone domain MED134_RS11010 120fda50184ae249b305cee10a417252 874 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 144 743 1.5E-213 T 22-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 211 2.7E-23 T 22-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 525 548 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 292 311 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 482 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 422 433 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 497 519 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 PRINTS PR01183 Ribonucleotide reductase large chain signature 593 620 1.9E-57 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 Pfam PF02867 Ribonucleotide reductase, barrel domain 215 739 3.6E-187 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MED134_RS11010 120fda50184ae249b305cee10a417252 874 SUPERFAMILY SSF48168 6 213 3.4E-69 T 22-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 MED134_RS00735 077d2a25c5358739693f82844a497ba3 252 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MED134_RS00735 077d2a25c5358739693f82844a497ba3 252 SUPERFAMILY SSF55008 1 59 5.5E-15 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS00735 077d2a25c5358739693f82844a497ba3 252 Gene3D G3DSA:3.30.70.100 1 58 5.9E-18 T 22-04-2016 MED134_RS00735 077d2a25c5358739693f82844a497ba3 252 Pfam PF00403 Heavy-metal-associated domain 4 49 8.1E-11 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MED134_RS14360 5b59339081f18452316b2dd6643980f2 579 Gene3D G3DSA:3.50.50.60 2 175 1.2E-7 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14360 5b59339081f18452316b2dd6643980f2 579 SUPERFAMILY SSF51905 323 412 8.68E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14360 5b59339081f18452316b2dd6643980f2 579 SUPERFAMILY SSF51905 1 177 8.68E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14360 5b59339081f18452316b2dd6643980f2 579 Pfam PF13454 FAD-NAD(P)-binding 5 174 1.7E-28 T 22-04-2016 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 183 363 1.9E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 62 6.8E-6 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 SUPERFAMILY SSF161098 160 349 6.93E-25 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 Gene3D G3DSA:1.10.3720.10 159 363 1.5E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 PANTHER PTHR30465:SF2 1 79 6.6E-96 T 22-04-2016 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 PANTHER PTHR30465:SF2 148 363 6.6E-96 T 22-04-2016 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 PANTHER PTHR30465 1 79 6.6E-96 T 22-04-2016 MED134_RS06420 0ec371f5979862ccb08f8d718c41e693 366 PANTHER PTHR30465 148 363 6.6E-96 T 22-04-2016 MED134_RS10915 91f0a17c1fdfef7a7da780a8a300e75c 355 Pfam PF06283 Trehalose utilisation 90 328 2.6E-28 T 22-04-2016 IPR029010 ThuA-like domain MED134_RS10915 91f0a17c1fdfef7a7da780a8a300e75c 355 Gene3D G3DSA:3.40.50.880 81 348 1.9E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS10915 91f0a17c1fdfef7a7da780a8a300e75c 355 SUPERFAMILY SSF52317 82 193 2.98E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS10915 91f0a17c1fdfef7a7da780a8a300e75c 355 SUPERFAMILY SSF52317 221 344 2.98E-39 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 Gene3D G3DSA:3.10.180.10 187 386 1.7E-84 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 PANTHER PTHR11959 21 386 1.8E-178 T 22-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 27 386 1.2E-138 T 22-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 193 340 7.3E-18 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 Gene3D G3DSA:3.10.180.10 21 186 2.3E-44 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 PIRSF PIRSF009283 14 386 5.9E-140 T 22-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 31 127 1.5E-6 T 22-04-2016 MED134_RS07745 6df578ba25718e969384c1bb1fab56c7 386 SUPERFAMILY SSF54593 22 373 6.15E-98 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 Gene3D G3DSA:3.90.950.10 9 192 1.4E-54 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 SUPERFAMILY SSF52972 7 191 2.94E-54 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 PIRSF PIRSF006305 2 194 2.7E-50 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 Hamap MF_00528 Septum formation protein Maf [maf]. 10 194 21.836 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 Pfam PF02545 Maf-like protein 11 191 7.8E-49 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 MED134_RS00235 1958be99db3d68714838a1047e8d1ad6 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 189 2.3E-38 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 SUPERFAMILY SSF52374 3 327 8.19E-102 T 22-04-2016 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 430 43.679 T 22-04-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 Gene3D G3DSA:3.40.50.620 2 236 7.0E-101 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 166 181 2.2E-28 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 187 209 2.2E-28 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 2.2E-28 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 220 232 2.2E-28 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PANTHER PTHR11766 3 431 1.1E-202 T 22-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 Gene3D G3DSA:3.10.290.10 321 430 5.2E-24 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 Gene3D G3DSA:1.10.240.10 237 320 1.0E-41 T 22-04-2016 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 SUPERFAMILY SSF55174 334 429 2.16E-11 T 22-04-2016 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 429 1.9E-124 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 PANTHER PTHR11766:SF0 3 431 1.1E-202 T 22-04-2016 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 Pfam PF00579 tRNA synthetases class I (W and Y) 32 327 1.4E-83 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS10740 7b59ba37fa4c4f75f1bc695e37686201 431 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 MED134_RS06350 bcefb16bf3d528c74771cb6168e4d28d 381 SUPERFAMILY SSF51445 52 379 5.56E-72 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS06350 bcefb16bf3d528c74771cb6168e4d28d 381 Gene3D G3DSA:3.20.20.80 22 380 3.8E-87 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS06350 bcefb16bf3d528c74771cb6168e4d28d 381 PANTHER PTHR31297 64 377 3.0E-20 T 22-04-2016 MED134_RS06350 bcefb16bf3d528c74771cb6168e4d28d 381 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 81 352 1.9E-59 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 MED134_RS06350 bcefb16bf3d528c74771cb6168e4d28d 381 PANTHER PTHR31297:SF17 64 377 3.0E-20 T 22-04-2016 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 Gene3D G3DSA:3.30.1490.10 76 132 1.7E-29 T 22-04-2016 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 132 30.673 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 PANTHER PTHR11758 1 132 1.9E-50 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 Pfam PF00410 Ribosomal protein S8 4 132 2.0E-49 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 SUPERFAMILY SSF56047 1 132 3.14E-43 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 MED134_RS12305 89fd35dc378a93ccaff95446a07aef0a 132 Gene3D G3DSA:3.30.1370.30 1 67 9.8E-25 T 22-04-2016 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 Pfam PF04389 Peptidase family M28 111 321 2.1E-19 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 SUPERFAMILY SSF49265 356 442 6.85E-7 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 PANTHER PTHR12147 288 358 2.4E-21 T 22-04-2016 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 PANTHER PTHR12147 28 255 2.4E-21 T 22-04-2016 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 Gene3D G3DSA:2.60.40.10 360 437 4.9E-7 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 Gene3D G3DSA:3.40.630.10 28 359 1.6E-42 T 22-04-2016 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 SUPERFAMILY SSF53187 24 218 2.26E-47 T 22-04-2016 MED134_RS02100 dd0af954a72977469f20403235eb0ab4 446 SUPERFAMILY SSF53187 247 354 2.26E-47 T 22-04-2016 MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 PANTHER PTHR11941:SF76 1 256 2.9E-90 T 22-04-2016 MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 SUPERFAMILY SSF52096 2 258 1.42E-79 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 258 7.6E-68 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 Gene3D G3DSA:3.90.226.10 1 257 1.1E-79 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS11510 23d07e07dae74a03052373455f086dd0 259 PANTHER PTHR11941 1 256 2.9E-90 T 22-04-2016 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 Pfam PF00202 Aminotransferase class-III 21 418 3.6E-104 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 SUPERFAMILY SSF53383 5 420 1.89E-111 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 PANTHER PTHR11986:SF8 2 421 5.4E-153 T 22-04-2016 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 Gene3D G3DSA:3.90.1150.10 3 59 9.4E-44 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 Gene3D G3DSA:3.90.1150.10 324 420 9.4E-44 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 Gene3D G3DSA:3.40.640.10 60 320 1.7E-79 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 PANTHER PTHR11986 2 421 5.4E-153 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS07930 323002b7d5b3addffd02781a20914d72 421 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 11 418 3.5E-163 T 22-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 MED134_RS12100 4fc8992ec47a077cafd1e82420c333d5 257 SUPERFAMILY SSF49464 26 103 7.19E-6 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 786 803 - T 22-04-2016 IPR010917 TonB-dependent receptor, conserved site MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 Pfam PF07715 TonB-dependent Receptor Plug Domain 111 218 5.8E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 SUPERFAMILY SSF56935 90 282 9.46E-96 T 22-04-2016 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 SUPERFAMILY SSF56935 316 803 9.46E-96 T 22-04-2016 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 Gene3D G3DSA:2.40.170.20 221 803 4.8E-66 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 Gene3D G3DSA:2.170.130.10 91 220 2.4E-31 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 Pfam PF00593 TonB dependent receptor 538 802 1.4E-22 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 PANTHER PTHR32552 313 803 1.5E-39 T 22-04-2016 MED134_RS09820 adb04d74ca4035045c16bbb768b0c459 803 PANTHER PTHR32552 93 282 1.5E-39 T 22-04-2016 MED134_RS04250 77896beef6c35ac1eeb77304b597a08a 340 Pfam PF04018 Domain of unknown function (DUF368) 21 278 4.8E-78 T 22-04-2016 IPR007163 Protein of unknown function DUF368 MED134_RS04250 77896beef6c35ac1eeb77304b597a08a 340 PANTHER PTHR37308 5 331 9.3E-49 T 22-04-2016 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Gene3D G3DSA:1.25.40.10 146 214 3.3E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Pfam PF13181 Tetratricopeptide repeat 370 402 0.0028 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 PANTHER PTHR23083 28 417 7.5E-65 T 22-04-2016 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Gene3D G3DSA:1.25.40.10 31 145 1.1E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Pfam PF13432 Tetratricopeptide repeat 238 294 0.0027 T 22-04-2016 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SUPERFAMILY SSF81901 201 436 3.14E-30 T 22-04-2016 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Pfam PF14559 Tetratricopeptide repeat 76 137 1.6E-6 T 22-04-2016 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SUPERFAMILY SSF48452 25 266 2.28E-27 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 Gene3D G3DSA:1.25.40.10 215 443 8.7E-41 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 165 198 52.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 29 62 24.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 131 164 0.17 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 233 266 0.02 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 97 130 0.2 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 199 232 4.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 301 334 51.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 267 300 0.19 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 369 402 0.031 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS04260 76063e94d562d6ebc3f7c70592ae8ca1 462 SMART SM00028 63 96 36.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 Gene3D G3DSA:3.30.360.10 128 316 4.7E-25 T 22-04-2016 MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 PANTHER PTHR22604:SF14 1 315 4.5E-65 T 22-04-2016 MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 117 2.5E-24 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 Gene3D G3DSA:3.40.50.720 1 127 4.3E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 SUPERFAMILY SSF51735 2 155 1.98E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 SUPERFAMILY SSF55347 138 237 3.6E-13 T 22-04-2016 MED134_RS05130 903130756a5c63bd80db68cfe802e23a 319 PANTHER PTHR22604 1 315 4.5E-65 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 SUPERFAMILY SSF52540 215 344 1.01E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01655 47b326f4db52931e64d565446a71d144 507 SUPERFAMILY SSF52540 37 167 1.01E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01655 47b326f4db52931e64d565446a71d144 507 SMART SM00487 11 193 7.7E-18 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain MED134_RS01655 47b326f4db52931e64d565446a71d144 507 Pfam PF04851 Type III restriction enzyme, res subunit 13 164 1.5E-19 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031:SF311 216 354 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031:SF311 465 501 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031:SF311 14 174 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 Pfam PF00271 Helicase conserved C-terminal domain 236 340 2.0E-14 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS01655 47b326f4db52931e64d565446a71d144 507 Gene3D G3DSA:3.40.50.300 10 166 1.5E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS01655 47b326f4db52931e64d565446a71d144 507 SMART SM00490 260 341 6.0E-8 T 22-04-2016 IPR001650 Helicase, C-terminal MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031 216 354 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031 465 501 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 PANTHER PTHR24031 14 174 4.0E-34 T 22-04-2016 MED134_RS01655 47b326f4db52931e64d565446a71d144 507 Gene3D G3DSA:3.40.50.300 233 345 1.3E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11200 21c0ae43fa0abd587a0e9e2942acd736 457 PANTHER PTHR34856:SF1 27 446 2.5E-204 T 22-04-2016 MED134_RS11200 21c0ae43fa0abd587a0e9e2942acd736 457 Pfam PF03916 Polysulphide reductase, NrfD 70 394 7.1E-21 T 22-04-2016 IPR005614 NrfD family MED134_RS11200 21c0ae43fa0abd587a0e9e2942acd736 457 PANTHER PTHR34856 27 446 2.5E-204 T 22-04-2016 MED134_RS11380 c33a5a9351576726773e5f61b684fd8b 414 Pfam PF12704 MacB-like periplasmic core domain 21 237 2.1E-22 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS11380 c33a5a9351576726773e5f61b684fd8b 414 Pfam PF02687 FtsX-like permease family 290 407 6.9E-19 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS11380 c33a5a9351576726773e5f61b684fd8b 414 PANTHER PTHR30572 1 414 2.2E-53 T 22-04-2016 MED134_RS12690 92a716e2496382d28c4c3e3b42058ee1 185 SMART SM00014 61 174 3.2E-19 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS12690 92a716e2496382d28c4c3e3b42058ee1 185 SUPERFAMILY SSF48317 3 183 7.85E-33 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS12690 92a716e2496382d28c4c3e3b42058ee1 185 Gene3D G3DSA:1.20.144.10 4 183 4.0E-30 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS12690 92a716e2496382d28c4c3e3b42058ee1 185 PANTHER PTHR14969 1 174 9.1E-21 T 22-04-2016 MED134_RS12690 92a716e2496382d28c4c3e3b42058ee1 185 Pfam PF01569 PAP2 superfamily 65 178 3.1E-23 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS05185 386d46ebb08ee1ff0693a0a54156fce6 338 PANTHER PTHR22916 2 272 2.3E-53 T 22-04-2016 MED134_RS05185 386d46ebb08ee1ff0693a0a54156fce6 338 SUPERFAMILY SSF53448 4 249 2.25E-45 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS05185 386d46ebb08ee1ff0693a0a54156fce6 338 PANTHER PTHR22916:SF30 2 272 2.3E-53 T 22-04-2016 MED134_RS05185 386d46ebb08ee1ff0693a0a54156fce6 338 Gene3D G3DSA:3.90.550.10 6 214 3.3E-36 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS05185 386d46ebb08ee1ff0693a0a54156fce6 338 Pfam PF00535 Glycosyl transferase family 2 6 132 3.3E-24 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS09180 25b8d37593f4e297492746f095d5c571 277 Gene3D G3DSA:3.40.50.150 73 273 2.8E-38 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09180 25b8d37593f4e297492746f095d5c571 277 SUPERFAMILY SSF53335 72 241 1.97E-35 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09180 25b8d37593f4e297492746f095d5c571 277 PANTHER PTHR10108 87 239 1.6E-16 T 22-04-2016 MED134_RS09180 25b8d37593f4e297492746f095d5c571 277 PANTHER PTHR10108:SF779 87 239 1.6E-16 T 22-04-2016 MED134_RS09180 25b8d37593f4e297492746f095d5c571 277 Pfam PF13489 Methyltransferase domain 71 222 2.5E-23 T 22-04-2016 MED134_RS10360 cac068d04749b2b4ae801b489914211e 378 Pfam PF00535 Glycosyl transferase family 2 41 157 7.8E-18 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS10360 cac068d04749b2b4ae801b489914211e 378 Gene3D G3DSA:3.90.550.10 40 274 5.7E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS10360 cac068d04749b2b4ae801b489914211e 378 PANTHER PTHR22916 40 378 5.4E-19 T 22-04-2016 MED134_RS10360 cac068d04749b2b4ae801b489914211e 378 Gene3D G3DSA:1.20.1640.10 281 341 4.5E-4 T 22-04-2016 MED134_RS10360 cac068d04749b2b4ae801b489914211e 378 SUPERFAMILY SSF53448 36 284 8.84E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 Gene3D G3DSA:4.10.520.10 1 90 3.8E-35 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 SMART SM00411 1 90 2.8E-36 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 PANTHER PTHR33175 1 90 7.4E-39 T 22-04-2016 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.4E-31 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.1E-13 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.1E-13 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.1E-13 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 MED134_RS13980 4ba47dc3673355d506078d37eb176b55 90 SUPERFAMILY SSF47729 1 90 1.07E-29 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MED134_RS06500 b164cb389d22366a565bf734878e1cb1 459 SUPERFAMILY SSF48452 37 383 1.52E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS06500 b164cb389d22366a565bf734878e1cb1 459 SMART SM00028 334 367 0.0036 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS06500 b164cb389d22366a565bf734878e1cb1 459 SMART SM00028 297 330 65.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS06500 b164cb389d22366a565bf734878e1cb1 459 Gene3D G3DSA:1.25.40.10 300 419 6.5E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS06500 b164cb389d22366a565bf734878e1cb1 459 SUPERFAMILY SSF48452 295 381 6.56E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 Pfam PF01025 GrpE 27 189 6.4E-40 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 SUPERFAMILY SSF51064 141 189 3.4E-9 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 PRINTS PR00773 GrpE protein signature 60 76 2.6E-22 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 PRINTS PR00773 GrpE protein signature 170 189 2.6E-22 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 PRINTS PR00773 GrpE protein signature 142 157 2.6E-22 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 PRINTS PR00773 GrpE protein signature 88 103 2.6E-22 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 Gene3D G3DSA:2.30.22.10 133 188 3.5E-14 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 Hamap MF_01151 Protein GrpE [grpE]. 8 191 17.343 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 SUPERFAMILY SSF58014 41 133 7.72E-22 T 22-04-2016 MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 Gene3D G3DSA:3.90.20.20 37 131 6.5E-23 T 22-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil MED134_RS13200 d2224c2bb7c83d33696b25da8fa08700 191 PANTHER PTHR21237 18 183 4.6E-33 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 PANTHER PTHR23416 1 182 2.0E-88 T 22-04-2016 MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 127 159 4.7E-4 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 PANTHER PTHR23416:SF36 1 182 2.0E-88 T 22-04-2016 MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 SUPERFAMILY SSF51161 20 179 6.93E-36 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS09280 d504d5a13dc84e92bd3f00140a8079c5 182 Gene3D G3DSA:2.160.10.10 22 180 1.2E-36 T 22-04-2016 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 SUPERFAMILY SSF51445 27 385 2.21E-89 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Gene3D G3DSA:3.40.710.10 573 968 4.1E-70 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 SUPERFAMILY SSF52279 404 556 4.45E-7 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 285 302 - T 22-04-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 PANTHER PTHR30480 32 766 2.2E-101 T 22-04-2016 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Pfam PF00144 Beta-lactamase 601 953 1.5E-39 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 PANTHER PTHR30480:SF5 32 766 2.2E-101 T 22-04-2016 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Gene3D G3DSA:3.20.20.300 53 384 3.9E-88 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 SUPERFAMILY SSF56601 590 951 6.76E-65 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 49 362 4.4E-77 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Gene3D G3DSA:3.40.50.1700 395 555 1.3E-6 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MED134_RS03580 b5eb6f20c31ebc352decbf42acd5a6fb 973 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 404 556 4.2E-7 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 Gene3D G3DSA:3.40.50.720 5 256 1.6E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 PIRSF PIRSF000094 3 264 1.3E-45 T 22-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 PANTHER PTHR24322:SF317 163 196 5.5E-19 T 22-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 PANTHER PTHR24322:SF317 15 147 5.5E-19 T 22-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 PANTHER PTHR24322 163 196 5.5E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 PANTHER PTHR24322 15 147 5.5E-19 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 SUPERFAMILY SSF51735 7 256 5.85E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05190 ca4509eba11b64dc0a22f6ab6f593522 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 8.9E-57 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:3.40.50.740 373 482 2.9E-13 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:3.30.70.20 753 808 9.0E-38 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:3.30.70.20 932 1013 9.0E-38 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:3.30.70.20 841 853 9.0E-38 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 PANTHER PTHR11938 837 901 2.0E-28 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 PANTHER PTHR11938 931 995 2.0E-28 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 PANTHER PTHR11938 758 802 2.0E-28 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Pfam PF12838 4Fe-4S dicluster domain 881 976 6.0E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Pfam PF12838 4Fe-4S dicluster domain 762 866 2.7E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:2.40.40.20 549 692 6.1E-6 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 SUPERFAMILY SSF54862 839 901 6.38E-43 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 SUPERFAMILY SSF54862 755 806 6.38E-43 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 SUPERFAMILY SSF54862 931 1014 6.38E-43 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 SUPERFAMILY SSF53706 106 488 2.77E-16 T 22-04-2016 MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 TIGRFAM TIGR04519 MoCo_extend_TAT: MoCo/4Fe-4S cofactor protein extended Tat translocation domain 5 56 1.7E-17 T 22-04-2016 IPR030948 MoCo/4Fe-4S cofactor protein extended Tat translocation domain MED134_RS11195 969f120dcb8505588355a367d3a27fbd 1023 Gene3D G3DSA:3.30.70.20 854 901 8.1E-15 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Gene3D G3DSA:3.40.50.10490 449 615 1.2E-62 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Pfam PF01380 SIS domain 296 423 2.2E-32 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Pfam PF01380 SIS domain 469 597 1.5E-28 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 PANTHER PTHR10937:SF0 1 615 0.0 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 39.329 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Gene3D G3DSA:3.60.20.10 2 233 7.4E-75 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 SUPERFAMILY SSF53697 250 615 1.02E-116 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Gene3D G3DSA:3.40.50.10490 248 448 7.8E-81 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 1.8E-245 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 PANTHER PTHR10937 1 615 0.0 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 Pfam PF13522 Glutamine amidotransferase domain 63 196 1.8E-24 T 22-04-2016 MED134_RS07975 8bb553c001461677fb0313fd19e8db00 615 SUPERFAMILY SSF56235 2 228 3.0E-68 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS12880 6f2c54176444c479063c0515d87949db 279 Gene3D G3DSA:1.10.600.10 10 277 4.4E-53 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS12880 6f2c54176444c479063c0515d87949db 279 Pfam PF00494 Squalene/phytoene synthase 18 259 1.4E-38 T 22-04-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 MED134_RS12880 6f2c54176444c479063c0515d87949db 279 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 162 188 - T 22-04-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 MED134_RS12880 6f2c54176444c479063c0515d87949db 279 SUPERFAMILY SSF48576 12 277 1.63E-64 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS12880 6f2c54176444c479063c0515d87949db 279 PANTHER PTHR31480 16 277 7.9E-38 T 22-04-2016 MED134_RS12880 6f2c54176444c479063c0515d87949db 279 PANTHER PTHR31480:SF0 16 277 7.9E-38 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 Gene3D G3DSA:2.40.160.50 532 756 2.8E-16 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 Pfam PF01103 Surface antigen 462 754 1.6E-28 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815 91 232 6.6E-72 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815:SF13 264 551 6.6E-72 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815:SF13 569 756 6.6E-72 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815:SF13 91 232 6.6E-72 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815 264 551 6.6E-72 T 22-04-2016 MED134_RS01770 ddba265dde1d659c34df105e8ad6e8dc 756 PANTHER PTHR12815 569 756 6.6E-72 T 22-04-2016 MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 SUPERFAMILY SSF52540 1 219 9.55E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 Gene3D G3DSA:3.40.50.300 1 220 1.0E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 PANTHER PTHR24220 3 216 7.2E-96 T 22-04-2016 MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 SMART SM00382 26 218 8.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 Pfam PF00005 ABC transporter 17 168 2.5E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS02010 620ee212a991474344219c94c1f66ec5 221 PANTHER PTHR24220:SF111 3 216 7.2E-96 T 22-04-2016 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 Gene3D G3DSA:1.10.1740.10 6 96 9.7E-22 T 22-04-2016 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 Pfam PF04542 Sigma-70 region 2 24 89 3.3E-13 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 PANTHER PTHR30173:SF31 7 175 3.6E-31 T 22-04-2016 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 PANTHER PTHR30173 7 175 3.6E-31 T 22-04-2016 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 SUPERFAMILY SSF88659 119 175 7.48E-11 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 174 7.4E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 Gene3D G3DSA:1.10.10.10 122 176 6.2E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 Pfam PF04545 Sigma-70, region 4 127 174 9.3E-10 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS12640 163d72793bcc3874b04f59d04fed6aa8 179 SUPERFAMILY SSF88946 7 103 2.62E-20 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 SUPERFAMILY SSF50447 827 923 4.52E-33 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Gene3D G3DSA:2.40.30.10 596 689 2.0E-21 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Pfam PF00009 Elongation factor Tu GTP binding domain 427 585 1.8E-30 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 ProSitePatterns PS01176 Initiation factor 2 signature. 876 898 - T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Gene3D G3DSA:3.40.50.10050 725 804 2.2E-24 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 923 17.16 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 349 399 3.9E-12 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 346 925 8.4E-248 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Gene3D G3DSA:2.40.30.10 827 923 1.9E-38 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 SUPERFAMILY SSF50447 597 680 2.0E-22 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 PANTHER PTHR23115 778 921 3.5E-198 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 PANTHER PTHR23115 409 753 3.5E-198 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 SUPERFAMILY SSF52156 704 832 7.72E-37 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 SUPERFAMILY SSF52540 417 597 3.76E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Gene3D G3DSA:3.40.50.300 418 584 9.3E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 PANTHER PTHR23115:SF184 778 921 3.5E-198 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 PANTHER PTHR23115:SF184 409 753 3.5E-198 T 22-04-2016 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 428 584 8.1E-31 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 MED134_RS11180 6ab7922945a7b22701a49e3ae789ca31 926 Pfam PF11987 Translation-initiation factor 2 716 815 1.3E-36 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 Pfam PF00106 short chain dehydrogenase 2 192 7.8E-58 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.2E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.2E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.2E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.2E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.2E-28 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PANTHER PTHR24319:SF32 2 250 2.9E-67 T 22-04-2016 MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 SUPERFAMILY SSF51735 2 235 1.88E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 PANTHER PTHR24319 2 250 2.9E-67 T 22-04-2016 MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MED134_RS09970 26ade80a6cf521311537e890e98d4c85 250 Gene3D G3DSA:3.40.50.720 2 235 2.8E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 SMART SM00861 357 533 1.6E-42 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 SUPERFAMILY SSF52518 359 562 5.89E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624:SF21 160 315 9.3E-126 T 22-04-2016 MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624:SF21 344 693 9.3E-126 T 22-04-2016 MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624:SF21 1 140 9.3E-126 T 22-04-2016 MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 SUPERFAMILY SSF52922 549 691 9.55E-26 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Gene3D G3DSA:3.40.50.970 356 557 3.7E-61 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Gene3D G3DSA:3.40.50.970 2 345 1.9E-71 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624 160 315 9.3E-126 T 22-04-2016 IPR033247 Transketolase family MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624 344 693 9.3E-126 T 22-04-2016 IPR033247 Transketolase family MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 PANTHER PTHR11624 1 140 9.3E-126 T 22-04-2016 IPR033247 Transketolase family MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 SUPERFAMILY SSF52518 2 341 2.83E-45 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Gene3D G3DSA:3.40.50.920 568 689 1.4E-27 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Pfam PF02779 Transketolase, pyrimidine binding domain 366 531 2.2E-34 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Pfam PF02780 Transketolase, C-terminal domain 567 683 1.2E-20 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS11570 2b4a799f77de30570be70d3b1a80f567 693 Pfam PF00676 Dehydrogenase E1 component 35 327 7.4E-29 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 22-04-2016 IPR020595 MnmG-related, conserved site MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 PANTHER PTHR11806 1 623 0.0 T 22-04-2016 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 PANTHER PTHR11806:SF0 1 623 0.0 T 22-04-2016 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 SMART SM01228 550 621 9.2E-41 T 22-04-2016 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 SUPERFAMILY SSF51905 8 69 1.89E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 SUPERFAMILY SSF51905 100 262 1.89E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 22-04-2016 IPR020595 MnmG-related, conserved site MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 Gene3D G3DSA:3.50.50.60 6 174 5.7E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 623 6.2E-253 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 Pfam PF13932 GidA associated domain 402 619 1.0E-68 T 22-04-2016 IPR026904 GidA associated domain 3 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 Pfam PF01134 Glucose inhibited division protein A 9 399 2.2E-156 T 22-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 MED134_RS09175 7d0bfdefc9c10281cafc167afd3a5aec 625 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 625 40.656 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 MED134_RS06990 80873a34037be8a4c41a2baec46f7c18 270 Gene3D G3DSA:3.30.565.10 109 210 3.5E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06990 80873a34037be8a4c41a2baec46f7c18 270 SUPERFAMILY SSF55874 121 205 2.62E-6 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06990 80873a34037be8a4c41a2baec46f7c18 270 Pfam PF06580 Histidine kinase 56 136 2.1E-20 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MED134_RS06990 80873a34037be8a4c41a2baec46f7c18 270 PANTHER PTHR34220 1 262 5.7E-37 T 22-04-2016 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 PANTHER PTHR11835 3 358 3.1E-179 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 335 1.3E-135 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 345 2.1E-124 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 Gene3D G3DSA:3.40.718.10 2 349 4.4E-123 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 SMART SM01329 4 346 5.3E-179 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 350 45.042 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 SUPERFAMILY SSF53659 2 350 2.34E-117 T 22-04-2016 MED134_RS11790 96816635122b9aef2c64fb275f3b1a4f 371 PANTHER PTHR11835:SF35 3 358 3.1E-179 T 22-04-2016 MED134_RS05085 7ed24687e3f78551426d7e316768867c 111 Pfam PF01627 Hpt domain 24 104 9.5E-5 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS05085 7ed24687e3f78551426d7e316768867c 111 Gene3D G3DSA:1.20.120.160 4 103 2.9E-13 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS05085 7ed24687e3f78551426d7e316768867c 111 SUPERFAMILY SSF47226 4 102 2.22E-14 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS03570 382f4fd5375f49f7b172732125e2e887 164 SUPERFAMILY SSF56925 33 164 7.06E-8 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS03570 382f4fd5375f49f7b172732125e2e887 164 Gene3D G3DSA:2.40.160.20 32 139 9.2E-4 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 Pfam PF00106 short chain dehydrogenase 22 228 4.8E-26 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 4.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 4.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 4.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 226 4.2E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PANTHER PTHR24320:SF45 9 311 3.3E-101 T 22-04-2016 MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 Gene3D G3DSA:3.40.50.720 19 261 1.9E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 SUPERFAMILY SSF51735 20 263 7.3E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14425 c9d504db14e3dce9f5aee6bfdf6bdd1b 316 PANTHER PTHR24320 9 311 3.3E-101 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 PANTHER PTHR10314 4 362 4.5E-128 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Gene3D G3DSA:3.40.50.1100 153 324 9.3E-67 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Gene3D G3DSA:3.40.50.1100 2 42 9.3E-67 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 304 1.1E-68 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 SUPERFAMILY SSF53686 2 328 4.58E-95 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Gene3D G3DSA:3.40.50.1100 43 147 1.2E-35 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 SUPERFAMILY SSF54631 338 454 4.67E-16 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 PANTHER PTHR10314:SF104 4 362 4.5E-128 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Gene3D G3DSA:3.10.580.10 338 454 1.6E-16 T 22-04-2016 MED134_RS14570 a8acc86fc3ebec8acc3feef80e2f1379 454 Pfam PF00571 CBS domain 343 392 9.8E-7 T 22-04-2016 IPR000644 CBS domain MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 SUPERFAMILY SSF52172 5 182 1.42E-35 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 232 4.0E-15 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 Gene3D G3DSA:3.40.50.2300 4 131 4.7E-35 T 22-04-2016 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 Gene3D G3DSA:1.10.10.10 141 236 1.4E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 PANTHER PTHR26402:SF606 5 243 1.8E-57 T 22-04-2016 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 SMART SM00448 5 121 1.3E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 PANTHER PTHR26402 5 243 1.8E-57 T 22-04-2016 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 SMART SM00862 160 235 5.5E-15 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS14380 d777a39821418b75d5fbb7e581ee8bd7 243 Pfam PF00072 Response regulator receiver domain 7 120 8.2E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 SUPERFAMILY SSF51366 3 257 1.33E-75 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 SMART SM00934 16 254 4.8E-46 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 254 1.8E-69 T 22-04-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 PANTHER PTHR19278:SF1 4 225 2.5E-67 T 22-04-2016 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 Gene3D G3DSA:3.20.20.70 4 263 4.6E-64 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 PANTHER PTHR19278 4 225 2.5E-67 T 22-04-2016 MED134_RS03755 45eb11eaba780b38b4477f55b3fe3a99 273 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 45 245 3.6E-26 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS07420 920dc7b1a1d585b3d3bc595265257c50 893 Pfam PF13502 AsmA-like C-terminal region 566 791 5.4E-37 T 22-04-2016 IPR032712 AsmA-like, C-terminal MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 PANTHER PTHR10909 24 441 1.7E-144 T 22-04-2016 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 33 146 1.7E-31 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 PANTHER PTHR10909:SF320 24 441 1.7E-144 T 22-04-2016 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 SUPERFAMILY SSF56645 30 268 7.2E-74 T 22-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 SUPERFAMILY SSF47203 256 427 5.15E-41 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 152 164 - T 22-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Gene3D G3DSA:1.10.540.10 17 147 1.4E-36 T 22-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 257 419 6.7E-34 T 22-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Gene3D G3DSA:2.40.110.10 149 244 1.5E-33 T 22-04-2016 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Gene3D G3DSA:1.20.140.10 245 429 2.2E-57 T 22-04-2016 MED134_RS01140 0b1b7e27554335e617ae7ecdae47196e 604 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 150 244 9.3E-23 T 22-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 SUPERFAMILY SSF57863 89 222 3.4E-8 T 22-04-2016 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 235 3.7E-21 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 Gene3D G3DSA:2.40.50.140 2 85 7.1E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 Hamap MF_00201 DNA repair protein RecO [recO]. 1 237 16.469 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 PANTHER PTHR33991 1 224 3.9E-23 T 22-04-2016 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 Pfam PF02565 Recombination protein O C terminal 87 226 9.4E-18 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 Pfam PF11967 Recombination protein O N terminal 1 81 2.1E-20 T 22-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal MED134_RS09815 75402879750ebf1e184fdad44f9c2f07 239 SUPERFAMILY SSF50249 1 82 5.31E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 SUPERFAMILY SSF47240 3 245 1.05E-79 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 PIRSF PIRSF037834 1 251 1.4E-99 T 22-04-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 251 7.9E-85 T 22-04-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 Gene3D G3DSA:1.20.1260.10 2 251 1.0E-92 T 22-04-2016 IPR012347 Ferritin-related MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 PANTHER PTHR30458 1 251 1.3E-102 T 22-04-2016 MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 Pfam PF05138 Phenylacetic acid catabolic protein 3 251 5.8E-92 T 22-04-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 MED134_RS11500 f1d5f4d5e92535bc7e33e0de5bdc2008 251 PANTHER PTHR30458:SF1 1 251 1.3E-102 T 22-04-2016 MED134_RS07805 48314844ac7adf8c95316479edf0ed03 139 Gene3D G3DSA:3.40.50.2300 6 130 3.5E-24 T 22-04-2016 MED134_RS07805 48314844ac7adf8c95316479edf0ed03 139 Pfam PF00072 Response regulator receiver domain 7 127 3.6E-12 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07805 48314844ac7adf8c95316479edf0ed03 139 SMART SM00448 5 129 4.4E-10 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07805 48314844ac7adf8c95316479edf0ed03 139 PANTHER PTHR26402 5 106 2.8E-15 T 22-04-2016 MED134_RS07805 48314844ac7adf8c95316479edf0ed03 139 SUPERFAMILY SSF52172 6 132 3.98E-20 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 SUPERFAMILY SSF50104 3 115 1.4E-36 T 22-04-2016 IPR008991 Translation protein SH3-like domain MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 PANTHER PTHR15680 15 115 3.0E-30 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 PRINTS PR00061 Ribosomal protein L19 signature 89 114 5.7E-29 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 PRINTS PR00061 Ribosomal protein L19 signature 5 34 5.7E-29 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 PRINTS PR00061 Ribosomal protein L19 signature 35 64 5.7E-29 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 114 2.9E-40 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 PIRSF PIRSF002191 1 116 5.6E-41 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 Pfam PF01245 Ribosomal protein L19 4 114 1.3E-40 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS13930 57ebde22f7813e1e8582491f1407524e 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 115 25.754 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 SUPERFAMILY SSF52374 2 191 8.3E-54 T 22-04-2016 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 Gene3D G3DSA:3.40.50.620 2 192 5.1E-58 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 65 3.4E-9 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 191 2.5E-50 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 PANTHER PTHR12039 2 192 1.3E-37 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 Pfam PF01467 Cytidylyltransferase-like 5 165 1.1E-27 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MED134_RS09515 ab48a4351e654c7975b3411a31f86021 192 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 192 27.261 T 22-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 Pfam PF00303 Thymidylate synthase 2 274 1.1E-121 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 PRINTS PR00108 Thymidylate synthase family signature 169 195 1.1E-40 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.1E-40 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 PRINTS PR00108 Thymidylate synthase family signature 207 224 1.1E-40 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 PRINTS PR00108 Thymidylate synthase family signature 112 131 1.1E-40 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.1E-41 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 274 5.8E-89 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 Gene3D G3DSA:3.30.572.10 1 274 5.1E-130 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 Hamap MF_00008 Thymidylate synthase [thyA]. 1 274 45.25 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 SUPERFAMILY SSF55831 1 274 9.16E-128 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 MED134_RS07230 b57d77ad12e610c45d34ef57bbfb7cf2 274 PANTHER PTHR11548 1 274 3.7E-188 T 22-04-2016 MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 PANTHER PTHR33619 91 257 4.8E-32 T 22-04-2016 MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 PANTHER PTHR33619 45 69 4.8E-32 T 22-04-2016 MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 Pfam PF02563 Polysaccharide biosynthesis/export protein 45 139 3.2E-17 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 Pfam PF10531 SLBB domain 144 189 7.4E-7 T 22-04-2016 IPR019554 Soluble ligand binding domain MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 Gene3D G3DSA:3.10.560.10 136 223 5.1E-14 T 22-04-2016 MED134_RS01440 ef2612b5000b8947bba053dce9f24cdf 257 Gene3D G3DSA:3.30.1950.10 53 135 1.4E-17 T 22-04-2016 MED134_RS06730 1b21f777015b4a96423dc650f2b00ef2 401 Pfam PF12704 MacB-like periplasmic core domain 27 245 4.1E-6 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS06730 1b21f777015b4a96423dc650f2b00ef2 401 PANTHER PTHR30489 1 401 2.9E-34 T 22-04-2016 MED134_RS06730 1b21f777015b4a96423dc650f2b00ef2 401 Pfam PF02687 FtsX-like permease family 278 396 8.5E-11 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS08690 9a73f24f28535d142b2e3ff9f475715a 451 PANTHER PTHR32024 15 435 5.9E-118 T 22-04-2016 MED134_RS08690 9a73f24f28535d142b2e3ff9f475715a 451 Pfam PF02386 Cation transport protein 44 430 1.5E-50 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MED134_RS08690 9a73f24f28535d142b2e3ff9f475715a 451 PANTHER PTHR32024:SF1 15 435 5.9E-118 T 22-04-2016 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 PANTHER PTHR21071 1 339 2.2E-135 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Gene3D G3DSA:3.90.78.10 240 339 8.8E-41 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 216 339 3.7E-35 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Gene3D G3DSA:3.30.465.10 79 239 5.0E-51 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 339 6.9E-70 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 PANTHER PTHR21071:SF6 1 339 2.2E-135 T 22-04-2016 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Pfam PF01565 FAD binding domain 23 147 1.2E-14 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Gene3D G3DSA:3.30.43.10 7 70 7.6E-20 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 339 77.581 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 SUPERFAMILY SSF56176 8 192 2.04E-39 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MED134_RS05815 66958e8e809a59e2a3923b38b04a803c 339 SUPERFAMILY SSF56194 212 339 1.31E-44 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 Gene3D G3DSA:3.90.930.12 2 81 1.0E-28 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 179 3.3E-66 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 PRINTS PR00059 Ribosomal protein L6 signature 144 165 1.7E-24 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 PRINTS PR00059 Ribosomal protein L6 signature 70 95 1.7E-24 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 Pfam PF00347 Ribosomal protein L6 11 81 1.9E-17 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 Pfam PF00347 Ribosomal protein L6 89 166 3.6E-14 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 PIRSF PIRSF002162 1 180 2.5E-46 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 PANTHER PTHR11655:SF14 1 180 1.2E-78 T 22-04-2016 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 179 34.014 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 SUPERFAMILY SSF56053 1 81 4.06E-25 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 157 165 - T 22-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 Gene3D G3DSA:3.90.930.12 82 179 1.9E-33 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 SUPERFAMILY SSF56053 82 179 8.32E-30 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS12310 2e4ccbcd0f0af4024459fe45ba898d0b 180 PANTHER PTHR11655 1 180 1.2E-78 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 Gene3D G3DSA:2.60.40.1120 21 110 4.3E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 Pfam PF07715 TonB-dependent Receptor Plug Domain 133 213 1.8E-6 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 SUPERFAMILY SSF56935 120 704 1.9E-52 T 22-04-2016 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 Pfam PF13715 CarboxypepD_reg-like domain 22 105 4.4E-15 T 22-04-2016 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 Gene3D G3DSA:2.170.130.10 135 215 1.1E-5 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 SUPERFAMILY SSF49464 20 104 4.51E-14 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 PANTHER PTHR11532 4 105 5.2E-14 T 22-04-2016 MED134_RS00175 83313c5aec5f54b70961b979478fb20a 721 PANTHER PTHR11532:SF57 4 105 5.2E-14 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 PANTHER PTHR12053 32 468 1.6E-117 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 Pfam PF02225 PA domain 148 234 4.6E-5 T 22-04-2016 IPR003137 PA domain MED134_RS13240 f992f22742e6998631cceea166a2547e 475 Gene3D G3DSA:3.40.630.10 36 95 4.0E-57 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 Gene3D G3DSA:3.40.630.10 263 458 4.0E-57 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 PANTHER PTHR12053:SF3 32 468 1.6E-117 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 Pfam PF04389 Peptidase family M28 264 449 7.9E-19 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 SUPERFAMILY SSF53187 256 460 1.78E-52 T 22-04-2016 MED134_RS13240 f992f22742e6998631cceea166a2547e 475 SUPERFAMILY SSF53187 31 91 1.78E-52 T 22-04-2016 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Pfam PF00629 MAM domain, meprin/A5/mu 56 203 6.8E-21 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 SMART SM00560 1296 1429 9.9E-7 T 22-04-2016 IPR006558 LamG-like jellyroll fold MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 2086 2158 1.3E-7 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1281 1431 1.9E-29 T 22-04-2016 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 PANTHER PTHR23282 2146 2154 3.6E-17 T 22-04-2016 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 PANTHER PTHR23282 58 209 3.6E-17 T 22-04-2016 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 SUPERFAMILY SSF49899 46 204 4.91E-31 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Gene3D G3DSA:2.60.40.360 484 586 6.5E-10 T 22-04-2016 IPR008962 PapD-like MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Gene3D G3DSA:2.60.40.360 234 331 9.2E-9 T 22-04-2016 IPR008962 PapD-like MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Gene3D G3DSA:2.60.40.360 362 456 3.2E-12 T 22-04-2016 IPR008962 PapD-like MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 SUPERFAMILY SSF49899 1269 1437 5.17E-33 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 SMART SM00137 49 207 4.6E-5 T 22-04-2016 IPR000998 MAM domain GO:0016020 MED134_RS04710 a688290c055ba3f634fcfd3678ed6a7b 2159 Gene3D G3DSA:2.60.120.200 1273 1438 2.4E-31 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS12700 f20584467c0a9511950f2bd35d515891 213 SUPERFAMILY SSF53335 5 213 6.11E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12700 f20584467c0a9511950f2bd35d515891 213 Gene3D G3DSA:3.40.50.150 5 213 1.7E-66 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS12700 f20584467c0a9511950f2bd35d515891 213 PANTHER PTHR10509:SF14 6 211 1.1E-61 T 22-04-2016 MED134_RS12700 f20584467c0a9511950f2bd35d515891 213 Pfam PF01596 O-methyltransferase 15 211 2.5E-49 T 22-04-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 MED134_RS12700 f20584467c0a9511950f2bd35d515891 213 PANTHER PTHR10509 6 211 1.1E-61 T 22-04-2016 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PANTHER PTHR11019:SF65 35 134 1.2E-37 T 22-04-2016 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PANTHER PTHR11019:SF65 153 290 1.2E-37 T 22-04-2016 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 4.8E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 4.8E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 Gene3D G3DSA:1.10.10.60 181 235 8.6E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 Pfam PF12833 Helix-turn-helix domain 206 283 2.6E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 SUPERFAMILY SSF46689 182 233 9.56E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 Gene3D G3DSA:2.60.120.10 33 107 5.6E-7 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 Gene3D G3DSA:1.10.10.60 236 284 2.2E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 SUPERFAMILY SSF46689 235 286 7.17E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 SUPERFAMILY SSF51182 15 85 1.07E-6 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 SMART SM00342 199 282 1.6E-24 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 278 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PANTHER PTHR11019 35 134 1.2E-37 T 22-04-2016 MED134_RS10220 e16e12f12c5d11149ac2c2c4ed55d15b 290 PANTHER PTHR11019 153 290 1.2E-37 T 22-04-2016 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 Gene3D G3DSA:3.90.1150.10 275 420 1.6E-54 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 Gene3D G3DSA:3.40.640.10 37 267 4.2E-15 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 Pfam PF00266 Aminotransferase class-V 40 379 3.1E-16 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS12745 fa9f33872336048df2e798033be54a24 420 PANTHER PTHR14084:SF0 8 420 1.9E-214 T 22-04-2016 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 TIGRFAM TIGR01814 kynureninase: kynureninase 10 420 1.1E-136 T 22-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 PANTHER PTHR14084 8 420 1.9E-214 T 22-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 PIRSF PIRSF038800 2 420 3.3E-162 T 22-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 MED134_RS12745 fa9f33872336048df2e798033be54a24 420 SUPERFAMILY SSF53383 8 420 1.8E-75 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS12745 fa9f33872336048df2e798033be54a24 420 Hamap MF_01970 Kynureninase [kynU]. 2 420 45.35 T 22-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 MED134_RS01630 3c476554d435ba62763f23673c18c775 166 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 10 157 1.6E-41 T 22-04-2016 MED134_RS01630 3c476554d435ba62763f23673c18c775 166 SUPERFAMILY SSF50475 12 139 2.55E-24 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS01630 3c476554d435ba62763f23673c18c775 166 Gene3D G3DSA:2.30.110.10 8 165 1.4E-40 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS01630 3c476554d435ba62763f23673c18c775 166 PANTHER PTHR34818 6 165 2.7E-25 T 22-04-2016 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 Pfam PF01409 tRNA synthetases class II core domain (F) 88 334 4.3E-98 T 22-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 41 335 1.2E-93 T 22-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 Gene3D G3DSA:3.30.930.10 15 335 4.5E-118 T 22-04-2016 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 SUPERFAMILY SSF55681 88 335 1.12E-74 T 22-04-2016 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 PANTHER PTHR11538 88 335 1.0E-97 T 22-04-2016 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 334 41.103 T 22-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 18 83 1.1E-17 T 22-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MED134_RS09890 ef787be646ddacfa263764bbccdc721a 338 SUPERFAMILY SSF46589 14 90 1.36E-11 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 MED134_RS09915 55634ded3297871011b18a450541e24c 525 PANTHER PTHR11814:SF123 1 505 1.1E-174 T 22-04-2016 MED134_RS09915 55634ded3297871011b18a450541e24c 525 PANTHER PTHR11814 1 505 1.1E-174 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 MED134_RS09915 55634ded3297871011b18a450541e24c 525 Pfam PF00916 Sulfate permease family 5 390 1.2E-61 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 Gene3D G3DSA:3.30.565.10 574 699 9.0E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 703 3.7E-5 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 SUPERFAMILY SSF55874 574 700 1.38E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 SUPERFAMILY SSF55874 12 206 9.43E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 143 1.0E-18 T 22-04-2016 MED134_RS05695 2a9789937b21ef09bb5263873bd0fa8e 731 Gene3D G3DSA:3.30.565.10 20 212 5.1E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS10410 6e4a45dfaa938bf2716e41df76e59e4f 222 Gene3D G3DSA:3.40.50.720 2 207 3.9E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10410 6e4a45dfaa938bf2716e41df76e59e4f 222 SMART SM00859 4 103 0.0049 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MED134_RS10410 6e4a45dfaa938bf2716e41df76e59e4f 222 SUPERFAMILY SSF51735 1 204 3.19E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10410 6e4a45dfaa938bf2716e41df76e59e4f 222 PANTHER PTHR14097 1 222 6.9E-54 T 22-04-2016 MED134_RS10410 6e4a45dfaa938bf2716e41df76e59e4f 222 Pfam PF13460 NAD(P)H-binding 9 200 8.9E-12 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 PANTHER PTHR24220:SF497 6 202 2.5E-38 T 22-04-2016 MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 Pfam PF00005 ABC transporter 20 155 1.2E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 PANTHER PTHR24220 6 202 2.5E-38 T 22-04-2016 MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 SMART SM00382 29 203 2.4E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 SUPERFAMILY SSF52540 5 213 2.46E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09355 6f89b8c15bc4ded04d570b02c51bcfa7 220 Gene3D G3DSA:3.40.50.300 5 203 3.0E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 Gene3D G3DSA:3.30.70.20 182 252 2.5E-9 T 22-04-2016 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 302 2.1E-103 T 22-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 Pfam PF13484 4Fe-4S double cluster binding domain 184 248 2.3E-20 T 22-04-2016 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 4 307 46.433 T 22-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 Pfam PF08331 Domain of unknown function (DUF1730) 60 132 7.2E-21 T 22-04-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 PANTHER PTHR30002:SF4 11 302 1.7E-124 T 22-04-2016 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 PANTHER PTHR30002 11 302 1.7E-124 T 22-04-2016 MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 185 196 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MED134_RS11240 35d567a8f39b31e817a02110942ad07c 307 SUPERFAMILY SSF46548 131 248 2.51E-18 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 Gene3D G3DSA:3.40.50.2300 2 129 1.2E-22 T 22-04-2016 MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 PANTHER PTHR26402:SF522 2 129 8.1E-22 T 22-04-2016 MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 SUPERFAMILY SSF52172 1 130 4.7E-21 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 SMART SM00448 2 126 1.2E-13 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 Pfam PF00072 Response regulator receiver domain 4 120 4.9E-16 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07905 4ce3682f85aac7e244f9e8ab8c986a45 140 PANTHER PTHR26402 2 129 8.1E-22 T 22-04-2016 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 PIRSF PIRSF002808 1 423 4.0E-41 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 PANTHER PTHR11662 7 415 3.1E-99 T 22-04-2016 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 Gene3D G3DSA:1.20.1250.20 221 412 5.5E-21 T 22-04-2016 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 Pfam PF07690 Major Facilitator Superfamily 14 379 6.2E-57 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 SUPERFAMILY SSF103473 3 418 8.5E-81 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 PANTHER PTHR11662:SF277 7 415 3.1E-99 T 22-04-2016 MED134_RS10470 461fce1c2162f2a97fea205eb82ea3de 423 Gene3D G3DSA:1.20.1250.20 6 199 1.6E-51 T 22-04-2016 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 SUPERFAMILY SSF54364 1 64 1.96E-20 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 74 157 5.4E-31 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 Gene3D G3DSA:3.30.110.10 69 159 8.3E-32 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 63 1.2E-25 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 159 6.1E-47 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 PANTHER PTHR10938 1 159 4.9E-50 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 SUPERFAMILY SSF55200 73 159 3.4E-27 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 MED134_RS06310 7e70855e8b6c3dcccdf0205f90212d16 159 Gene3D G3DSA:3.10.20.80 1 66 6.8E-27 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 MED134_RS07910 c6739ec13a8415055559d0d892b565a4 281 Gene3D G3DSA:2.60.120.650 6 232 1.3E-38 T 22-04-2016 MED134_RS07910 c6739ec13a8415055559d0d892b565a4 281 SMART SM00558 106 252 0.0014 T 22-04-2016 IPR003347 JmjC domain MED134_RS07910 c6739ec13a8415055559d0d892b565a4 281 SUPERFAMILY SSF51197 5 272 6.45E-62 T 22-04-2016 MED134_RS07910 c6739ec13a8415055559d0d892b565a4 281 Pfam PF13621 Cupin-like domain 15 224 8.0E-37 T 22-04-2016 MED134_RS07910 c6739ec13a8415055559d0d892b565a4 281 PANTHER PTHR12461 5 221 2.5E-42 T 22-04-2016 MED134_RS12705 d723a395d2b77ff311f43c9e0f5575fc 363 PANTHER PTHR21240:SF3 11 356 2.3E-21 T 22-04-2016 IPR032465 Amino-carboxymuconate-semialdehyde decarboxylase GO:0001760|GO:0006568|GO:1904984 KEGG: 00380+4.1.1.45|MetaCyc: PWY-5647|MetaCyc: PWY-5652|MetaCyc: PWY-5654|UniPathway: UPA00270 MED134_RS12705 d723a395d2b77ff311f43c9e0f5575fc 363 Gene3D G3DSA:3.20.20.140 8 351 3.3E-39 T 22-04-2016 MED134_RS12705 d723a395d2b77ff311f43c9e0f5575fc 363 Pfam PF04909 Amidohydrolase 88 307 1.6E-14 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS12705 d723a395d2b77ff311f43c9e0f5575fc 363 PANTHER PTHR21240 11 356 2.3E-21 T 22-04-2016 MED134_RS12705 d723a395d2b77ff311f43c9e0f5575fc 363 SUPERFAMILY SSF51556 7 349 4.47E-53 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS13800 6cffe0b5f18a02f5851ac854b3773007 286 Gene3D G3DSA:2.60.120.200 32 284 1.3E-74 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS13800 6cffe0b5f18a02f5851ac854b3773007 286 SUPERFAMILY SSF49899 31 283 1.7E-70 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain MED134_RS13800 6cffe0b5f18a02f5851ac854b3773007 286 Pfam PF00722 Glycosyl hydrolases family 16 74 280 1.2E-30 T 22-04-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 MED134_RS13800 6cffe0b5f18a02f5851ac854b3773007 286 PANTHER PTHR10963 35 282 4.1E-48 T 22-04-2016 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 328 373 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 SMART SM00342 291 377 1.1E-10 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 SUPERFAMILY SSF46689 342 380 5.82E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 Gene3D G3DSA:1.10.10.60 344 380 2.0E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 PANTHER PTHR11019 109 139 9.8E-14 T 22-04-2016 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 PANTHER PTHR11019 248 385 9.8E-14 T 22-04-2016 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 PANTHER PTHR11019:SF50 109 139 9.8E-14 T 22-04-2016 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 PANTHER PTHR11019:SF50 248 385 9.8E-14 T 22-04-2016 MED134_RS14450 53f7808aa55abb309c71de5d3e7a9e5b 387 Pfam PF12833 Helix-turn-helix domain 297 378 1.9E-11 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS07730 a1d81a3db4e70238098a9bffb7c52d3a 430 PANTHER PTHR21666:SF207 180 385 8.2E-50 T 22-04-2016 MED134_RS07730 a1d81a3db4e70238098a9bffb7c52d3a 430 SUPERFAMILY SSF51261 125 377 1.1E-57 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS07730 a1d81a3db4e70238098a9bffb7c52d3a 430 Pfam PF01551 Peptidase family M23 282 376 8.5E-31 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS07730 a1d81a3db4e70238098a9bffb7c52d3a 430 PANTHER PTHR21666 180 385 8.2E-50 T 22-04-2016 MED134_RS07730 a1d81a3db4e70238098a9bffb7c52d3a 430 Gene3D G3DSA:2.70.70.10 240 377 3.2E-42 T 22-04-2016 MED134_RS09160 6c7af376759884f138f25e4e074307ba 349 PANTHER PTHR38674:SF1 16 340 6.9E-88 T 22-04-2016 MED134_RS09160 6c7af376759884f138f25e4e074307ba 349 PANTHER PTHR38674 16 340 6.9E-88 T 22-04-2016 MED134_RS09160 6c7af376759884f138f25e4e074307ba 349 Pfam PF00487 Fatty acid desaturase 101 317 6.3E-26 T 22-04-2016 IPR005804 Fatty acid desaturase domain GO:0006629 MED134_RS03140 81ad804567df4e73474a87a76e7170fe 356 Pfam PF04389 Peptidase family M28 125 336 4.8E-43 T 22-04-2016 IPR007484 Peptidase M28 MED134_RS03140 81ad804567df4e73474a87a76e7170fe 356 Gene3D G3DSA:3.40.630.10 47 348 1.0E-68 T 22-04-2016 MED134_RS03140 81ad804567df4e73474a87a76e7170fe 356 ProSitePatterns PS00018 EF-hand calcium-binding domain. 162 174 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS03140 81ad804567df4e73474a87a76e7170fe 356 PANTHER PTHR12147 52 343 3.2E-42 T 22-04-2016 MED134_RS03140 81ad804567df4e73474a87a76e7170fe 356 SUPERFAMILY SSF53187 50 345 3.14E-67 T 22-04-2016 MED134_RS11295 a18b36fe0bd8fbddea5cfe5624fc57f7 263 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 201 261 1.0E-7 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 MED134_RS11295 a18b36fe0bd8fbddea5cfe5624fc57f7 263 SUPERFAMILY SSF74653 200 259 2.22E-6 T 22-04-2016 MED134_RS09785 b0636ead8a89588c7b3f247728be32e6 240 Gene3D G3DSA:3.30.565.40 41 162 3.5E-15 T 22-04-2016 IPR025303 Domain of unknown function DUF4163 MED134_RS09785 b0636ead8a89588c7b3f247728be32e6 240 Pfam PF13739 Domain of unknown function (DUF4163) 44 145 2.5E-6 T 22-04-2016 IPR025303 Domain of unknown function DUF4163 MED134_RS10805 387bfe35cf72ce6bef957eed8739f1db 110 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 44 94 1.8E-5 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS10805 387bfe35cf72ce6bef957eed8739f1db 110 PANTHER PTHR23426 5 106 4.2E-22 T 22-04-2016 MED134_RS10805 387bfe35cf72ce6bef957eed8739f1db 110 SUPERFAMILY SSF54292 6 106 4.54E-21 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MED134_RS10805 387bfe35cf72ce6bef957eed8739f1db 110 Gene3D G3DSA:3.10.20.30 4 106 3.7E-27 T 22-04-2016 IPR012675 Beta-grasp domain MED134_RS00480 152c7d65f1a91a002554b82f51480aa3 90 Pfam PF12728 Helix-turn-helix domain 35 73 6.4E-7 T 22-04-2016 MED134_RS07430 3bd0edc6fc4baa7c6c4b85f5ceccd3e1 305 Pfam PF01734 Patatin-like phospholipase 4 195 1.4E-17 T 22-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 MED134_RS07430 3bd0edc6fc4baa7c6c4b85f5ceccd3e1 305 SUPERFAMILY SSF52151 2 292 1.07E-32 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MED134_RS07430 3bd0edc6fc4baa7c6c4b85f5ceccd3e1 305 Gene3D G3DSA:3.40.1090.10 2 196 1.1E-11 T 22-04-2016 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 SUPERFAMILY SSF52518 388 568 1.4E-21 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Gene3D G3DSA:3.40.50.970 387 560 5.8E-19 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 SUPERFAMILY SSF52518 4 199 8.62E-34 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 PIRSF PIRSF004983 3 572 1.6E-132 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 PANTHER PTHR18968 9 572 2.0E-117 T 22-04-2016 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 9 444 1.2E-105 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 2 571 28.432 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Pfam PF16582 Middle domain of thiamine pyrophosphate 290 402 2.2E-7 T 22-04-2016 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Gene3D G3DSA:3.40.50.970 4 195 2.9E-45 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 553 1.4E-5 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 192 6.5E-30 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MED134_RS13760 d5575af076f4824d135227f8d4e6ce90 572 PANTHER PTHR18968:SF114 9 572 2.0E-117 T 22-04-2016 MED134_RS14640 eb632467b46fe0a3a860a5a9f6543c92 210 Gene3D G3DSA:1.10.150.20 121 159 7.1E-6 T 22-04-2016 MED134_RS07565 68c1a83390cd817135b1ae0545f2e7a2 293 Pfam PF00691 OmpA family 171 272 3.1E-20 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07565 68c1a83390cd817135b1ae0545f2e7a2 293 PANTHER PTHR30329 85 281 5.9E-27 T 22-04-2016 MED134_RS07565 68c1a83390cd817135b1ae0545f2e7a2 293 Gene3D G3DSA:3.30.1330.60 151 278 5.4E-28 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS07565 68c1a83390cd817135b1ae0545f2e7a2 293 PANTHER PTHR30329:SF4 85 281 5.9E-27 T 22-04-2016 MED134_RS07565 68c1a83390cd817135b1ae0545f2e7a2 293 SUPERFAMILY SSF103088 162 280 9.03E-26 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03720 2f29518d73fe8063176027d56d9232eb 468 Gene3D G3DSA:1.10.606.10 156 463 3.8E-70 T 22-04-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 MED134_RS03720 2f29518d73fe8063176027d56d9232eb 468 PANTHER PTHR34599 155 461 3.8E-27 T 22-04-2016 MED134_RS03720 2f29518d73fe8063176027d56d9232eb 468 PANTHER PTHR34599:SF1 155 461 3.8E-27 T 22-04-2016 MED134_RS03720 2f29518d73fe8063176027d56d9232eb 468 Pfam PF01569 PAP2 superfamily 325 455 4.9E-11 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS03720 2f29518d73fe8063176027d56d9232eb 468 SUPERFAMILY SSF48317 270 461 3.92E-35 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 Pfam PF02348 Cytidylyltransferase 2 211 1.1E-42 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 230 9.1E-56 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 PANTHER PTHR21485:SF4 1 235 6.2E-73 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 PANTHER PTHR21485 1 235 6.2E-73 T 22-04-2016 MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 Gene3D G3DSA:3.90.550.10 1 238 6.1E-60 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS01315 7c0acf1fff7fdd46e1bae64b72d4c631 239 SUPERFAMILY SSF53448 1 232 3.38E-50 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS00970 7b79328e4e83f4870dd32a5bac85a444 179 PANTHER PTHR11608 1 179 1.7E-52 T 22-04-2016 MED134_RS00970 7b79328e4e83f4870dd32a5bac85a444 179 Pfam PF00156 Phosphoribosyl transferase domain 5 164 3.3E-18 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 MED134_RS00970 7b79328e4e83f4870dd32a5bac85a444 179 SUPERFAMILY SSF53271 4 171 1.02E-32 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS00970 7b79328e4e83f4870dd32a5bac85a444 179 Gene3D G3DSA:3.40.50.2020 3 172 1.4E-37 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS10405 8264d4c8f115d41c0dcc3bc082fac468 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 62 4.4E-5 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS10405 8264d4c8f115d41c0dcc3bc082fac468 122 Gene3D G3DSA:3.10.180.10 4 114 6.0E-15 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS10405 8264d4c8f115d41c0dcc3bc082fac468 122 SUPERFAMILY SSF54593 2 117 2.06E-17 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS04765 7ec1ec103d60873384b40c4a558614a7 243 PANTHER PTHR30292:SF0 1 243 2.1E-82 T 22-04-2016 MED134_RS04765 7ec1ec103d60873384b40c4a558614a7 243 PANTHER PTHR30292 1 243 2.1E-82 T 22-04-2016 MED134_RS04765 7ec1ec103d60873384b40c4a558614a7 243 SUPERFAMILY SSF88713 3 242 2.0E-81 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MED134_RS04765 7ec1ec103d60873384b40c4a558614a7 243 Pfam PF03746 LamB/YcsF family 4 235 1.4E-79 T 22-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF MED134_RS08450 13235f2d2da701cb00cf1e62db8b3c34 129 Pfam PF11026 Protein of unknown function (DUF2721) 7 121 2.9E-30 T 22-04-2016 IPR021279 Protein of unknown function DUF2721 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 Gene3D G3DSA:3.30.1360.40 249 324 3.5E-14 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 53 468 1.1E-107 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 SMART SM00434 32 466 6.4E-80 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 SUPERFAMILY SSF56719 33 488 8.24E-104 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 Gene3D G3DSA:3.90.199.10 328 380 1.3E-59 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 Gene3D G3DSA:3.90.199.10 52 248 1.3E-59 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 PANTHER PTHR10169 39 649 3.4E-116 T 22-04-2016 MED134_RS02595 8cf38c396235625d3fcb4101ba1dd1cb 893 PANTHER PTHR10169:SF48 39 649 3.4E-116 T 22-04-2016 MED134_RS11020 364e4ce38ebcb319a1dbf6c2f7c2cd52 116 SUPERFAMILY SSF82185 33 99 1.96E-7 T 22-04-2016 MED134_RS11020 364e4ce38ebcb319a1dbf6c2f7c2cd52 116 Gene3D G3DSA:2.20.110.10 31 99 1.4E-4 T 22-04-2016 MED134_RS02765 00b4363a382b31fb63442b396cc3e7e6 206 PANTHER PTHR30506 1 203 2.0E-69 T 22-04-2016 MED134_RS02765 00b4363a382b31fb63442b396cc3e7e6 206 Pfam PF03458 UPF0126 domain 92 163 6.5E-22 T 22-04-2016 IPR005115 Uncharacterised domain UPF0126 MED134_RS02765 00b4363a382b31fb63442b396cc3e7e6 206 Pfam PF03458 UPF0126 domain 6 78 1.2E-20 T 22-04-2016 IPR005115 Uncharacterised domain UPF0126 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 Gene3D G3DSA:2.40.50.140 1 123 1.7E-65 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 Pfam PF00164 Ribosomal protein S12/S23 8 123 1.9E-44 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 8.4E-69 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PIRSF PIRSF002133 1 124 5.2E-56 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.0E-59 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 SUPERFAMILY SSF50249 2 123 1.2E-52 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 PANTHER PTHR11652 1 116 2.3E-75 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12215 d142b371383a558b9ab7e29af2c0cce4 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.885 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 MED134_RS09695 e1a49d00d7a25ec89c029220caae8370 175 SUPERFAMILY SSF55729 2 160 2.55E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09695 e1a49d00d7a25ec89c029220caae8370 175 PANTHER PTHR13256:SF10 1 159 2.0E-32 T 22-04-2016 MED134_RS09695 e1a49d00d7a25ec89c029220caae8370 175 Gene3D G3DSA:3.40.630.30 1 160 5.1E-40 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09695 e1a49d00d7a25ec89c029220caae8370 175 Pfam PF13302 Acetyltransferase (GNAT) domain 10 154 8.4E-23 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS09695 e1a49d00d7a25ec89c029220caae8370 175 PANTHER PTHR13256 1 159 2.0E-32 T 22-04-2016 MED134_RS02465 4c204ee89f9def614a052fecfce7c1c1 149 SUPERFAMILY SSF160574 33 148 2.22E-21 T 22-04-2016 MED134_RS02465 4c204ee89f9def614a052fecfce7c1c1 149 Pfam PF11396 Putative beta-lactamase-inhibitor-like, PepSY-like 60 148 7.1E-12 T 22-04-2016 IPR021533 Putative beta-lactamase-inhibitor-like, PepSY-like MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 PANTHER PTHR30160:SF1 2 305 2.2E-28 T 22-04-2016 MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 61 303 9.4E-17 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 Gene3D G3DSA:3.40.50.2000 170 300 9.3E-16 T 22-04-2016 MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 PANTHER PTHR30160 2 305 2.2E-28 T 22-04-2016 MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 Gene3D G3DSA:3.40.50.2000 2 135 3.7E-24 T 22-04-2016 MED134_RS04335 52fef96ad43474cd780a6d11ca95694c 328 SUPERFAMILY SSF53756 2 301 4.08E-53 T 22-04-2016 MED134_RS07570 79224de935f69c1ebd288959cad931c9 333 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 4 317 5.8E-59 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS07570 79224de935f69c1ebd288959cad931c9 333 Pfam PF11751 Protein of unknown function (DUF3308) 22 315 1.6E-70 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 Pfam PF00574 Clp protease 10 181 4.9E-68 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PRINTS PR00127 Clp protease catalytic subunit P signature 158 177 1.5E-39 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PRINTS PR00127 Clp protease catalytic subunit P signature 10 25 1.5E-39 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PRINTS PR00127 Clp protease catalytic subunit P signature 49 69 1.5E-39 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PRINTS PR00127 Clp protease catalytic subunit P signature 101 120 1.5E-39 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PRINTS PR00127 Clp protease catalytic subunit P signature 80 97 1.5E-39 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 Gene3D G3DSA:3.90.226.10 10 180 1.4E-68 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 PANTHER PTHR10381 13 179 1.3E-85 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 SUPERFAMILY SSF52096 11 180 1.84E-61 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 102 115 - T 22-04-2016 IPR033135 ClpP, histidine active site MED134_RS10120 69c45c180a0eaa75e8a35a7e99e8c02a 182 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 182 32.43 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MED134_RS03925 685dd6e07f246bf6108a3c2a58d90f97 176 SUPERFAMILY SSF109854 4 175 4.58E-47 T 22-04-2016 MED134_RS03925 685dd6e07f246bf6108a3c2a58d90f97 176 Pfam PF12867 DinB superfamily 29 163 1.2E-15 T 22-04-2016 IPR024775 DinB-like domain MED134_RS03925 685dd6e07f246bf6108a3c2a58d90f97 176 Hamap MF_01256 Putative metal-dependent hydrolase . 2 176 35.7 T 22-04-2016 IPR023774 Putative metal-dependent hydrolase YfiT MED134_RS03925 685dd6e07f246bf6108a3c2a58d90f97 176 Gene3D G3DSA:1.20.120.450 1 175 7.5E-62 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 Gene3D G3DSA:3.40.1280.10 2 150 2.2E-56 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 PIRSF PIRSF029256 2 151 6.2E-55 T 22-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 SUPERFAMILY SSF75217 2 150 1.31E-37 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 PANTHER PTHR12029:SF31 2 150 3.7E-58 T 22-04-2016 MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 Pfam PF00588 SpoU rRNA Methylase family 3 143 2.8E-33 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 PANTHER PTHR12029 2 150 3.7E-58 T 22-04-2016 MED134_RS12850 2c9c2cd8ee81319f6233f0bdcc7465a6 151 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 151 32.012 T 22-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 Pfam PF04552 Sigma-54, DNA binding domain 322 479 2.0E-50 T 22-04-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 479 3.3E-120 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 3 47 4.4E-12 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PRINTS PR00045 Sigma-54 factor signature 181 198 3.8E-22 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PRINTS PR00045 Sigma-54 factor signature 455 473 3.8E-22 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PRINTS PR00045 Sigma-54 factor signature 397 408 3.8E-22 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PRINTS PR00045 Sigma-54 factor signature 381 393 3.8E-22 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PANTHER PTHR32248 1 481 1.4E-136 T 22-04-2016 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PANTHER PTHR32248:SF4 1 481 1.4E-136 T 22-04-2016 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 Pfam PF04963 Sigma-54 factor, core binding domain 107 299 8.9E-54 T 22-04-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 460 467 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS05920 a49d71922ccb40407f45ba6ae76232eb 481 PIRSF PIRSF000774 1 481 2.4E-133 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 PIRSF PIRSF006603 5 437 2.4E-55 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 14 413 3.6E-75 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 Pfam PF01554 MatE 14 177 3.7E-24 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 Pfam PF01554 MatE 261 396 1.4E-13 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 PANTHER PTHR11206 6 433 3.8E-73 T 22-04-2016 MED134_RS09020 e944aabb4580a952139ca953fc8c12c3 441 PANTHER PTHR11206:SF94 6 433 3.8E-73 T 22-04-2016 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 23 126 2.8E-29 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 PANTHER PTHR13501 20 127 1.4E-33 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 Gene3D G3DSA:3.90.470.10 20 131 8.9E-36 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 18 130 24.44 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 SUPERFAMILY SSF54843 13 131 7.72E-35 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MED134_RS12260 60257107b243e573aec8e51f75e4fb16 136 Pfam PF00237 Ribosomal protein L22p/L17e 25 127 2.1E-28 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MED134_RS09600 0c70ae1d601c50ef8534ea4f1d124e3f 264 PANTHER PTHR30622 1 264 5.6E-85 T 22-04-2016 MED134_RS09600 0c70ae1d601c50ef8534ea4f1d124e3f 264 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 261 16.878 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MED134_RS09600 0c70ae1d601c50ef8534ea4f1d124e3f 264 Pfam PF02673 Bacitracin resistance protein BacA 6 256 3.6E-72 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MED134_RS09600 0c70ae1d601c50ef8534ea4f1d124e3f 264 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 254 2.9E-65 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MED134_RS11890 218b175aeabb1637e61819a3a973abe2 160 SUPERFAMILY SSF53927 20 160 4.35E-36 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 MED134_RS11890 218b175aeabb1637e61819a3a973abe2 160 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 22 126 7.2E-16 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 MED134_RS11890 218b175aeabb1637e61819a3a973abe2 160 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 73 119 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MED134_RS11890 218b175aeabb1637e61819a3a973abe2 160 PANTHER PTHR11644 17 160 3.9E-35 T 22-04-2016 MED134_RS11890 218b175aeabb1637e61819a3a973abe2 160 Gene3D G3DSA:3.40.140.10 22 159 4.3E-39 T 22-04-2016 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 480 490 - T 22-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PANTHER PTHR10795:SF419 82 120 8.2E-49 T 22-04-2016 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PANTHER PTHR10795:SF419 305 519 8.2E-49 T 22-04-2016 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PANTHER PTHR10795 82 120 8.2E-49 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PANTHER PTHR10795 305 519 8.2E-49 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 305 318 1.7E-18 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 479 495 1.7E-18 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PRINTS PR00723 Subtilisin serine protease family (S8) signature 82 101 1.7E-18 T 22-04-2016 IPR015500 Peptidase S8, subtilisin-related MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 Gene3D G3DSA:3.40.50.200 49 131 5.3E-10 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 87 98 - T 22-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 Gene3D G3DSA:3.40.50.200 257 554 7.9E-66 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 309 319 - T 22-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 SUPERFAMILY SSF52743 69 123 1.37E-59 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 SUPERFAMILY SSF52743 309 551 1.37E-59 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 PIRSF PIRSF037892 1 557 6.0E-225 T 22-04-2016 IPR017308 Peptidase S8A, subtilisin-related, bacteroidetes MED134_RS09035 72f2eca5635f6104919e4cd3d40728e6 557 Pfam PF00082 Subtilase family 257 514 9.3E-43 T 22-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MED134_RS12920 f4c4fb748e12ddbd78cbeafa925659b2 131 SUPERFAMILY SSF55174 1 82 1.7E-19 T 22-04-2016 MED134_RS12920 f4c4fb748e12ddbd78cbeafa925659b2 131 Gene3D G3DSA:3.10.290.10 1 85 2.2E-24 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12920 f4c4fb748e12ddbd78cbeafa925659b2 131 Pfam PF01479 S4 domain 1 47 9.7E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12920 f4c4fb748e12ddbd78cbeafa925659b2 131 SMART SM00363 1 62 1.3E-5 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 MED134_RS12920 f4c4fb748e12ddbd78cbeafa925659b2 131 PIRSF PIRSF016821 1 123 1.2E-43 T 22-04-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 SUPERFAMILY SSF143597 37 242 1.44E-58 T 22-04-2016 MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 PIRSF PIRSF004793 4 257 2.3E-65 T 22-04-2016 IPR014046 Diadenylate cyclase-like MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 Gene3D G3DSA:3.40.1700.10 117 241 4.7E-43 T 22-04-2016 MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 PANTHER PTHR34185 2 257 1.1E-67 T 22-04-2016 MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 PANTHER PTHR34185:SF1 2 257 1.1E-67 T 22-04-2016 MED134_RS03965 31e6e808016899b45d5d7f2a5d697e4e 257 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 121 238 1.3E-38 T 22-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal MED134_RS02550 44dda94335dc4c15fb6fb200af5bb569 135 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 7 131 4.4E-32 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MED134_RS02550 44dda94335dc4c15fb6fb200af5bb569 135 Gene3D G3DSA:3.40.50.300 8 134 2.1E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02550 44dda94335dc4c15fb6fb200af5bb569 135 PANTHER PTHR33540 1 135 2.2E-30 T 22-04-2016 MED134_RS02550 44dda94335dc4c15fb6fb200af5bb569 135 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 130 1.6E-36 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MED134_RS02550 44dda94335dc4c15fb6fb200af5bb569 135 SUPERFAMILY SSF52540 24 114 1.69E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 SUPERFAMILY SSF52172 1 133 1.57E-25 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 SUPERFAMILY SSF46894 141 205 1.05E-17 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 Gene3D G3DSA:3.40.50.2300 2 118 4.3E-25 T 22-04-2016 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 5.1E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 5.1E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 5.1E-13 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 PANTHER PTHR26402 2 204 1.2E-50 T 22-04-2016 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 Pfam PF00072 Response regulator receiver domain 4 115 3.5E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 Gene3D G3DSA:1.10.10.10 119 205 2.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 SMART SM00448 2 115 1.5E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 SMART SM00421 147 204 9.4E-20 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 PANTHER PTHR26402:SF151 2 204 1.2E-50 T 22-04-2016 MED134_RS12455 facd853ccfc6cadd6403cb238125ba3f 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 3.4E-18 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MED134_RS01060 1b98fc9c8eada02adb103ee1df6a7358 288 SUPERFAMILY SSF53067 112 283 9.84E-43 T 22-04-2016 MED134_RS01060 1b98fc9c8eada02adb103ee1df6a7358 288 PANTHER PTHR12862 1 247 3.4E-22 T 22-04-2016 MED134_RS01060 1b98fc9c8eada02adb103ee1df6a7358 288 SUPERFAMILY SSF53067 1 105 9.07E-33 T 22-04-2016 MED134_RS09505 025233efc0a349924c88ea14814cdef6 166 SMART SM00257 113 162 1.3E-9 T 22-04-2016 IPR018392 LysM domain MED134_RS09505 025233efc0a349924c88ea14814cdef6 166 Pfam PF01476 LysM domain 114 162 5.8E-9 T 22-04-2016 IPR018392 LysM domain MED134_RS09505 025233efc0a349924c88ea14814cdef6 166 PANTHER PTHR34700 21 162 7.3E-26 T 22-04-2016 MED134_RS09505 025233efc0a349924c88ea14814cdef6 166 Gene3D G3DSA:3.10.350.10 111 162 2.5E-9 T 22-04-2016 IPR018392 LysM domain MED134_RS09505 025233efc0a349924c88ea14814cdef6 166 SUPERFAMILY SSF54106 112 162 8.5E-8 T 22-04-2016 IPR018392 LysM domain MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 PANTHER PTHR38474:SF1 4 207 2.7E-58 T 22-04-2016 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 SMART SM01059 1 203 1.0E-66 T 22-04-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 PANTHER PTHR38474 4 207 2.7E-58 T 22-04-2016 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 Pfam PF00302 Chloramphenicol acetyltransferase 2 202 5.1E-30 T 22-04-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 6 196 7.0E-31 T 22-04-2016 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 SUPERFAMILY SSF52777 2 208 1.2E-43 T 22-04-2016 MED134_RS09860 33451ae58cd15e9b9b7ed794a178e408 210 Gene3D G3DSA:3.30.559.10 2 207 1.6E-65 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 SUPERFAMILY SSF48557 10 392 5.5E-99 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 424 29.059 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.7E-18 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 1.7E-18 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.7E-18 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 1.7E-18 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PANTHER PTHR11444 11 392 1.3E-115 T 22-04-2016 IPR000362 Fumarate lyase family MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 1.5E-34 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00145 Argininosuccinate lyase family signature 193 209 1.5E-34 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 1.5E-34 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.5E-34 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 1.5E-34 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 Gene3D G3DSA:1.10.275.10 1 106 7.2E-28 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 Pfam PF00206 Lyase 9 299 3.4E-58 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 Gene3D G3DSA:1.20.200.10 107 385 4.9E-73 T 22-04-2016 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 PANTHER PTHR11444:SF3 11 392 1.3E-115 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11775 f274222e577371ade2000ba8a43be51a 427 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 406 2.3E-102 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 Gene3D G3DSA:2.60.40.1120 28 107 2.0E-10 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 SUPERFAMILY SSF49464 29 108 3.66E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 Gene3D G3DSA:2.40.170.20 232 717 6.9E-47 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 Pfam PF07715 TonB-dependent Receptor Plug Domain 120 227 7.1E-18 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 Pfam PF13715 CarboxypepD_reg-like domain 29 109 1.0E-15 T 22-04-2016 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 PANTHER PTHR30069:SF2 3 588 3.1E-32 T 22-04-2016 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 PANTHER PTHR30069 3 588 3.1E-32 T 22-04-2016 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 SUPERFAMILY SSF56935 102 716 4.27E-75 T 22-04-2016 MED134_RS00720 7038d4277bc6f95a30cf6722ca85ea86 728 Gene3D G3DSA:2.170.130.10 108 231 4.4E-30 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS10060 c2f333c74244a601fdb57eac81684706 511 PANTHER PTHR38657 4 511 2.2E-203 T 22-04-2016 MED134_RS10060 c2f333c74244a601fdb57eac81684706 511 PANTHER PTHR38657:SF1 4 511 2.2E-203 T 22-04-2016 MED134_RS10060 c2f333c74244a601fdb57eac81684706 511 Gene3D G3DSA:1.25.40.80 225 320 1.2E-9 T 22-04-2016 MED134_RS10060 c2f333c74244a601fdb57eac81684706 511 SUPERFAMILY SSF48173 230 492 4.97E-55 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS10060 c2f333c74244a601fdb57eac81684706 511 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 225 9.6E-75 T 22-04-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 SUPERFAMILY SSF51735 121 289 2.89E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 Hamap MF_01576 Bifunctional protein FolD [folD]. 1 291 36.736 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 Gene3D G3DSA:3.40.50.720 138 272 3.9E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 122 290 1.9E-64 T 22-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 268 276 - T 22-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 Gene3D G3DSA:3.40.192.10 5 137 1.5E-44 T 22-04-2016 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 3 119 7.1E-37 T 22-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 74 99 - T 22-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 SUPERFAMILY SSF53223 2 120 8.06E-38 T 22-04-2016 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PANTHER PTHR10025 2 286 7.3E-154 T 22-04-2016 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 206 235 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 247 263 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 264 282 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS03445 63a989b2a35306f26f458df3a77c6575 297 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 153 173 1.6E-78 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 SMART SM00905 4 116 2.7E-28 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 Pfam PF02152 Dihydroneopterin aldolase 4 113 1.3E-24 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 TIGRFAM TIGR00526 folB_dom: FolB domain 2 113 1.5E-13 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 SUPERFAMILY SSF55620 2 117 1.5E-23 T 22-04-2016 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 Gene3D G3DSA:3.30.1130.10 1 118 5.1E-30 T 22-04-2016 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 113 3.3E-23 T 22-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 MED134_RS09115 e494f9480add457c5e485c33061d7fbb 118 PANTHER PTHR20941 1 113 5.6E-16 T 22-04-2016 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 SUPERFAMILY SSF48256 4 428 6.67E-147 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 360 376 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 241 269 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 219 234 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 380 394 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 165 178 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PRINTS PR00143 Citrate synthase signature 297 317 5.2E-49 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PANTHER PTHR11739 10 428 7.8E-178 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 Gene3D G3DSA:1.10.580.10 52 280 8.0E-90 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 PIRSF PIRSF001369 38 428 1.4E-144 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 Gene3D G3DSA:1.10.230.10 281 374 6.7E-37 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 12 421 3.1E-159 T 22-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 Pfam PF00285 Citrate synthase, C-terminal domain 46 411 2.1E-126 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 MED134_RS12385 4533e90300787278ba9b7c3831edc59a 428 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 22-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 MED134_RS05310 9013029928f8bf1e95eb4a270d1aed19 148 Pfam PF14534 Domain of unknown function (DUF4440) 32 141 1.3E-14 T 22-04-2016 IPR027843 Domain of unknown function DUF4440 MED134_RS05310 9013029928f8bf1e95eb4a270d1aed19 148 SUPERFAMILY SSF54427 27 142 2.51E-14 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS05310 9013029928f8bf1e95eb4a270d1aed19 148 Gene3D G3DSA:3.10.450.50 29 142 3.7E-4 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 SUPERFAMILY SSF102405 84 281 1.21E-24 T 22-04-2016 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 PANTHER PTHR32039:SF8 61 366 1.8E-81 T 22-04-2016 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 Gene3D G3DSA:1.10.150.20 15 53 8.1E-5 T 22-04-2016 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 Gene3D G3DSA:3.40.50.450 114 234 1.1E-5 T 22-04-2016 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 PANTHER PTHR32039 61 366 1.8E-81 T 22-04-2016 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 Pfam PF02481 DNA recombination-mediator protein A 74 281 1.2E-68 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 SUPERFAMILY SSF47781 4 57 1.91E-7 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS09495 afbfc4706c076cd19c13a64fb4a2e830 367 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 287 3.7E-63 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 SUPERFAMILY SSF48452 68 258 5.31E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 Pfam PF13424 Tetratricopeptide repeat 195 254 3.7E-7 T 22-04-2016 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 SMART SM00028 109 142 23.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 SMART SM00028 304 337 140.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 SMART SM00028 189 222 0.31 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 PANTHER PTHR24421 539 636 1.7E-16 T 22-04-2016 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 SUPERFAMILY SSF55874 541 635 6.18E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 Gene3D G3DSA:3.30.565.10 544 636 1.0E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 Gene3D G3DSA:1.25.40.10 35 38 3.6E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 Gene3D G3DSA:1.25.40.10 76 241 3.6E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 Gene3D G3DSA:1.25.40.10 280 337 3.6E-22 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07620 33b6b7fdf7c204e5187b254656227ece 636 PANTHER PTHR24421:SF15 539 636 1.7E-16 T 22-04-2016 MED134_RS05950 c52237b8024593470391c5603a86bb3f 264 PANTHER PTHR30625 46 262 7.1E-61 T 22-04-2016 MED134_RS05950 c52237b8024593470391c5603a86bb3f 264 PANTHER PTHR30625:SF8 46 262 7.1E-61 T 22-04-2016 MED134_RS05950 c52237b8024593470391c5603a86bb3f 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 129 249 4.8E-29 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 SUPERFAMILY SSF56954 6 441 4.32E-79 T 22-04-2016 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 PANTHER PTHR30026:SF7 6 441 1.7E-43 T 22-04-2016 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 Pfam PF02321 Outer membrane efflux protein 250 438 4.1E-33 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 Pfam PF02321 Outer membrane efflux protein 34 227 2.8E-23 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 Gene3D G3DSA:1.20.1600.10 31 441 7.0E-66 T 22-04-2016 MED134_RS06050 b1abfe53ecf455a30e2c0bacdda18cea 445 PANTHER PTHR30026 6 441 1.7E-43 T 22-04-2016 MED134_RS03095 8052bde1b9e9e8ae33681ac13154a449 470 Gene3D G3DSA:3.40.30.10 329 462 4.9E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS03095 8052bde1b9e9e8ae33681ac13154a449 470 SUPERFAMILY SSF52833 330 468 1.5E-8 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 182 201 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 PIRSF PIRSF000525 1 354 5.6E-122 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 354 42.426 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 PANTHER PTHR21152:SF1 4 353 8.8E-135 T 22-04-2016 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 PANTHER PTHR21152 4 353 8.8E-135 T 22-04-2016 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 Gene3D G3DSA:3.90.1150.10 253 353 1.8E-30 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 Gene3D G3DSA:3.40.640.10 16 251 7.5E-87 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 SUPERFAMILY SSF53383 2 352 9.37E-97 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS02980 439d87b55896e3795bd33a1a242ffbec 354 Pfam PF00266 Aminotransferase class-V 5 340 5.3E-35 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS12275 094ee514bf84cb2cb420c644fbd03c97 62 SUPERFAMILY SSF46561 1 61 4.84E-17 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12275 094ee514bf84cb2cb420c644fbd03c97 62 Pfam PF00831 Ribosomal L29 protein 4 60 3.9E-18 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12275 094ee514bf84cb2cb420c644fbd03c97 62 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 13.921 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12275 094ee514bf84cb2cb420c644fbd03c97 62 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 59 5.2E-11 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12275 094ee514bf84cb2cb420c644fbd03c97 62 Gene3D G3DSA:1.10.287.310 1 61 3.2E-19 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 Pfam PF05299 M61 glycyl aminopeptidase 278 395 4.6E-34 T 22-04-2016 IPR007963 Peptidase M61, catalytic domain MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 Gene3D G3DSA:2.30.42.10 481 566 6.0E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 SUPERFAMILY SSF50156 501 566 1.84E-12 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 PIRSF PIRSF016493 14 588 5.2E-129 T 22-04-2016 IPR024191 Peptidase M61 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 SUPERFAMILY SSF55486 208 462 1.12E-13 T 22-04-2016 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 Pfam PF13180 PDZ domain 481 561 2.1E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS07945 7e130ad69fbb27b1b3f1e7a161f6744f 590 SMART SM00228 481 552 4.8E-6 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Pfam PF07676 WD40-like Beta Propeller Repeat 220 243 0.002 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Pfam PF07676 WD40-like Beta Propeller Repeat 331 368 2.8E-6 T 22-04-2016 IPR011659 WD40-like Beta Propeller MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 SUPERFAMILY SSF103088 522 646 1.96E-29 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 SUPERFAMILY SSF48452 39 129 3.8E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Gene3D G3DSA:1.25.40.10 27 129 7.9E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 SUPERFAMILY SSF82171 157 418 6.15E-15 T 22-04-2016 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Pfam PF00691 OmpA family 540 629 2.0E-17 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 PANTHER PTHR30128 529 647 5.5E-33 T 22-04-2016 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Gene3D G3DSA:3.30.1330.60 534 647 3.7E-33 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Pfam PF13620 Carboxypeptidase regulatory-like domain 436 505 3.7E-9 T 22-04-2016 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Gene3D G3DSA:2.130.10.10 204 423 5.3E-10 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 Gene3D G3DSA:2.60.40.10 438 480 5.6E-8 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 PRINTS PR01021 OMPA domain signature 586 602 1.2E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 PRINTS PR01021 OMPA domain signature 541 563 1.2E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 PRINTS PR01021 OMPA domain signature 571 586 1.2E-12 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MED134_RS10325 3a8216b6ad0de36feb4192e3adae0840 649 SUPERFAMILY SSF49478 436 489 1.65E-8 T 22-04-2016 MED134_RS01000 b14fed6e9d1d1b5546492cb105b970c2 160 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 102 3.7E-8 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 MED134_RS01000 b14fed6e9d1d1b5546492cb105b970c2 160 Gene3D G3DSA:3.40.50.1240 1 151 2.5E-39 T 22-04-2016 IPR029033 Histidine phosphatase superfamily MED134_RS01000 b14fed6e9d1d1b5546492cb105b970c2 160 SMART SM00855 3 116 1.2E-4 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 MED134_RS01000 b14fed6e9d1d1b5546492cb105b970c2 160 SUPERFAMILY SSF53254 1 151 1.96E-22 T 22-04-2016 IPR029033 Histidine phosphatase superfamily MED134_RS01840 fe44b94310fbf3f1ea3fb081c0e5e24c 120 Pfam PF13564 DoxX-like family 36 114 1.3E-14 T 22-04-2016 IPR032808 DoxX family MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 SUPERFAMILY SSF51556 295 319 1.79E-49 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 SUPERFAMILY SSF51556 98 251 1.79E-49 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 SUPERFAMILY SSF51556 348 438 1.79E-49 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 SUPERFAMILY SSF51338 29 99 5.34E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 SUPERFAMILY SSF51338 437 467 5.34E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Gene3D G3DSA:3.20.20.140 101 250 6.8E-46 T 22-04-2016 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Gene3D G3DSA:3.20.20.140 294 435 6.8E-46 T 22-04-2016 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Pfam PF01979 Amidohydrolase family 95 223 2.4E-5 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Pfam PF01979 Amidohydrolase family 376 488 1.7E-15 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Gene3D G3DSA:2.30.40.10 30 100 2.6E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 Gene3D G3DSA:2.30.40.10 437 495 2.6E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 PANTHER PTHR11271 1 273 7.2E-14 T 22-04-2016 MED134_RS04280 63815be4cd1e6bbaeac1623aaabc7060 522 PANTHER PTHR11271 367 516 7.2E-14 T 22-04-2016 MED134_RS01415 4ce3cf830a0962fe794f5a934a90f26e 199 Pfam PF02397 Bacterial sugar transferase 7 181 1.2E-56 T 22-04-2016 IPR003362 Bacterial sugar transferase MED134_RS01415 4ce3cf830a0962fe794f5a934a90f26e 199 PANTHER PTHR30576 1 189 1.3E-86 T 22-04-2016 MED134_RS01415 4ce3cf830a0962fe794f5a934a90f26e 199 PANTHER PTHR30576:SF8 1 189 1.3E-86 T 22-04-2016 MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 Pfam PF02082 Transcriptional regulator 1 81 1.4E-24 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 PANTHER PTHR33221:SF1 1 135 1.2E-43 T 22-04-2016 MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 SUPERFAMILY SSF46785 1 135 3.87E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 Gene3D G3DSA:1.10.10.10 1 135 1.0E-33 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 135 1.5E-33 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type MED134_RS05465 cd9fec74a4a130ec7ec8813d22865e56 135 PANTHER PTHR33221 1 135 1.2E-43 T 22-04-2016 MED134_RS11540 3ea0690457aa641b9f8da9a5b13b45f0 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 227 9.2E-32 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MED134_RS11540 3ea0690457aa641b9f8da9a5b13b45f0 250 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MED134_RS11540 3ea0690457aa641b9f8da9a5b13b45f0 250 PANTHER PTHR11941 10 221 1.8E-34 T 22-04-2016 MED134_RS11540 3ea0690457aa641b9f8da9a5b13b45f0 250 SUPERFAMILY SSF52096 2 249 1.06E-44 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS11540 3ea0690457aa641b9f8da9a5b13b45f0 250 Gene3D G3DSA:3.90.226.10 2 249 5.8E-43 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS13440 f4cf5d33f08c556e494d33d6c44f985a 488 Pfam PF00535 Glycosyl transferase family 2 220 339 3.1E-13 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13440 f4cf5d33f08c556e494d33d6c44f985a 488 Gene3D G3DSA:3.90.550.10 220 414 1.1E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13440 f4cf5d33f08c556e494d33d6c44f985a 488 SUPERFAMILY SSF53448 220 476 1.41E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13440 f4cf5d33f08c556e494d33d6c44f985a 488 PANTHER PTHR22916 221 405 4.0E-15 T 22-04-2016 MED134_RS14355 8bfc35fd60d6fe314d5ceec7810bccfb 167 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 90 165 1.1E-20 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MED134_RS14355 8bfc35fd60d6fe314d5ceec7810bccfb 167 Gene3D G3DSA:3.10.50.30 89 165 1.6E-19 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MED134_RS14355 8bfc35fd60d6fe314d5ceec7810bccfb 167 SUPERFAMILY SSF54534 90 165 6.8E-15 T 22-04-2016 MED134_RS14355 8bfc35fd60d6fe314d5ceec7810bccfb 167 PIRSF PIRSF006092 19 166 2.1E-20 T 22-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 160 5.7E-47 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 116 133 - T 22-04-2016 IPR001882 Biotin-binding site MED134_RS06680 e784621c858108136414089e1f7aabbe 162 PANTHER PTHR23151 1 159 5.2E-37 T 22-04-2016 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 SUPERFAMILY SSF51230 84 159 5.89E-22 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS06680 e784621c858108136414089e1f7aabbe 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 106 120 2.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 121 134 2.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 89 102 2.0E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 PANTHER PTHR23151:SF64 1 159 5.2E-37 T 22-04-2016 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 Gene3D G3DSA:2.40.50.100 84 159 3.5E-27 T 22-04-2016 MED134_RS06680 e784621c858108136414089e1f7aabbe 162 Pfam PF00364 Biotin-requiring enzyme 86 157 6.1E-20 T 22-04-2016 IPR000089 Biotin/lipoyl attachment MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 326 7.3E-33 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 95 101 - T 22-04-2016 IPR014762 DNA mismatch repair, conserved site MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 128 9.5E-12 T 22-04-2016 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 SUPERFAMILY SSF54211 192 327 9.1E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 SUPERFAMILY SSF118116 445 626 1.57E-40 T 22-04-2016 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 PANTHER PTHR10073 5 554 1.1E-122 T 22-04-2016 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Gene3D G3DSA:3.30.565.10 5 203 8.0E-69 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 SMART SM01340 209 327 3.9E-45 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Gene3D G3DSA:3.30.230.10 204 326 2.6E-32 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 5 306 9.9E-90 T 22-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 SUPERFAMILY SSF55874 5 204 8.38E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Pfam PF08676 MutL C terminal dimerisation domain 446 585 5.2E-27 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 3 625 22.724 T 22-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MED134_RS05415 3c9fcd18c445ca9cb9a111f7b051df2b 626 SMART SM00853 443 585 3.1E-27 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MED134_RS03115 c7523c4fd28b85af19bd1adb4bc32d1e 210 Pfam PF00881 Nitroreductase family 9 186 1.3E-18 T 22-04-2016 IPR029479 Nitroreductase MED134_RS03115 c7523c4fd28b85af19bd1adb4bc32d1e 210 Gene3D G3DSA:3.40.109.10 3 206 1.6E-56 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS03115 c7523c4fd28b85af19bd1adb4bc32d1e 210 SUPERFAMILY SSF55469 3 207 1.96E-47 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS03115 c7523c4fd28b85af19bd1adb4bc32d1e 210 PANTHER PTHR23026 3 210 1.7E-30 T 22-04-2016 MED134_RS03115 c7523c4fd28b85af19bd1adb4bc32d1e 210 PANTHER PTHR23026:SF101 3 210 1.7E-30 T 22-04-2016 MED134_RS02730 d3e7f64de773e7198b50a342c7bc2f23 494 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 358 476 1.1E-9 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MED134_RS02730 d3e7f64de773e7198b50a342c7bc2f23 494 Pfam PF01943 Polysaccharide biosynthesis protein 5 285 4.9E-11 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 SUPERFAMILY SSF101821 77 183 1.21E-26 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 Pfam PF05343 M42 glutamyl aminopeptidase 53 344 9.4E-77 T 22-04-2016 IPR008007 Peptidase M42 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 Gene3D G3DSA:3.40.630.10 8 77 4.2E-72 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 Gene3D G3DSA:3.40.630.10 172 355 4.2E-72 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 SUPERFAMILY SSF53187 178 350 1.07E-57 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 SUPERFAMILY SSF53187 10 88 1.07E-57 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 Gene3D G3DSA:2.40.30.40 78 165 8.2E-25 T 22-04-2016 IPR023367 Peptidase M42, domain 2 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 PANTHER PTHR32481 6 362 4.7E-115 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 PANTHER PTHR32481:SF10 6 362 4.7E-115 T 22-04-2016 MED134_RS13815 2132c4885c08a48f202a4c66b07a84ef 362 PIRSF PIRSF001123 8 361 2.0E-90 T 22-04-2016 IPR008007 Peptidase M42 MED134_RS10130 609b6c961e760f0ed4faab486e8bbaf4 228 PANTHER PTHR36434 1 228 1.4E-78 T 22-04-2016 MED134_RS10130 609b6c961e760f0ed4faab486e8bbaf4 228 Pfam PF04298 Putative neutral zinc metallopeptidase 3 221 5.0E-86 T 22-04-2016 IPR007395 Putative neutral zinc metallopeptidase MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 SUPERFAMILY SSF47240 33 276 3.45E-84 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 PANTHER PTHR30458 10 319 6.7E-159 T 22-04-2016 MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 13 301 8.8E-161 T 22-04-2016 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149+1.14.13.14|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176|UniPathway: UPA00930 MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 Pfam PF05138 Phenylacetic acid catabolic protein 23 297 9.2E-102 T 22-04-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 Gene3D G3DSA:1.20.1260.10 23 277 1.6E-104 T 22-04-2016 IPR012347 Ferritin-related MED134_RS11490 363e255b27c5b31e58957215c12b253c 320 PANTHER PTHR30458:SF0 10 319 6.7E-159 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Gene3D G3DSA:3.40.50.720 163 449 7.6E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 PIRSF PIRSF036684 1 757 0.0 T 22-04-2016 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 SUPERFAMILY SSF53223 11 163 2.66E-53 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Pfam PF00390 Malic enzyme, N-terminal domain 22 153 3.3E-28 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 SUPERFAMILY SSF51735 165 443 2.71E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 SMART SM01274 20 153 1.8E-80 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 ProSitePatterns PS00331 Malic enzymes signature. 161 177 - T 22-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 PANTHER PTHR23406:SF23 33 356 1.7E-160 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 PANTHER PTHR23406:SF23 373 448 1.7E-160 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 SUPERFAMILY SSF53659 431 754 4.07E-90 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 SMART SM00919 165 401 2.0E-128 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Pfam PF01515 Phosphate acetyl/butaryl transferase 431 749 1.2E-90 T 22-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Pfam PF03949 Malic enzyme, NAD binding domain 167 362 4.1E-22 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 PANTHER PTHR23406 33 356 1.7E-160 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 PANTHER PTHR23406 373 448 1.7E-160 T 22-04-2016 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Gene3D G3DSA:3.40.50.10380 7 162 2.6E-52 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MED134_RS11265 22045f50e045dc7d1bf7d559801833cb 764 Gene3D G3DSA:3.40.50.10750 566 725 1.3E-52 T 22-04-2016 MED134_RS00260 12a1ce9836cf2100bb6aab5845649573 445 Gene3D G3DSA:1.10.10.10 390 443 1.6E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00260 12a1ce9836cf2100bb6aab5845649573 445 SUPERFAMILY SSF46894 385 444 4.76E-5 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS00260 12a1ce9836cf2100bb6aab5845649573 445 Pfam PF07696 7TMR-DISM extracellular 2 22 100 1.1E-4 T 22-04-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 Hamap MF_01974 Methionine aminopeptidase [map]. 3 249 38.154 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 247 8.8E-88 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 Gene3D G3DSA:3.90.230.10 4 249 3.5E-79 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PANTHER PTHR10804 1 247 5.3E-105 T 22-04-2016 MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 SUPERFAMILY SSF55920 4 247 2.49E-76 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 68 81 2.0E-18 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 2.0E-18 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 2.0E-18 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 2.0E-18 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 Pfam PF00557 Metallopeptidase family M24 12 238 2.9E-45 T 22-04-2016 IPR000994 Peptidase M24, structural domain MED134_RS06965 f94a07bdfe82141e39d70c37de50daab 273 PANTHER PTHR10804:SF41 1 247 5.3E-105 T 22-04-2016 MED134_RS01740 a9316f73729f8851808b929f97ad9b16 292 Gene3D G3DSA:3.40.50.620 15 144 1.4E-12 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS01740 a9316f73729f8851808b929f97ad9b16 292 SUPERFAMILY SSF52402 16 182 6.58E-13 T 22-04-2016 MED134_RS01740 a9316f73729f8851808b929f97ad9b16 292 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 56 185 6.7E-7 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 MED134_RS08160 9d2fd88233e5987213d38f0c60cb247e 142 Gene3D G3DSA:1.10.3680.10 13 63 1.0E-7 T 22-04-2016 IPR029024 TerB-like MED134_RS08160 9d2fd88233e5987213d38f0c60cb247e 142 SUPERFAMILY SSF158682 14 118 1.31E-13 T 22-04-2016 IPR029024 TerB-like MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PANTHER PTHR30295:SF6 1 155 3.8E-52 T 22-04-2016 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PIRSF PIRSF005900 1 157 7.8E-40 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 ProSitePatterns PS00818 Dps protein family signature 1. 39 55 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 Gene3D G3DSA:1.20.1260.10 5 155 1.2E-50 T 22-04-2016 IPR012347 Ferritin-related MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PANTHER PTHR30295 1 155 3.8E-52 T 22-04-2016 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 SUPERFAMILY SSF47240 5 156 1.39E-39 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 134 152 7.0E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 63 79 7.0E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 39 55 7.0E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS12580 525c1e47b54922eff0d1b8fb00df4cce 157 Pfam PF00210 Ferritin-like domain 19 155 1.2E-21 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MED134_RS08530 8779d170e58110ec9abf737608e00bdb 157 Pfam PF10677 Protein of unknown function (DUF2490) 9 139 3.2E-22 T 22-04-2016 IPR019619 Protein of unknown function DUF2490 MED134_RS08405 a0fef60d25a68aa93cbfd985bf6f5795 84 SUPERFAMILY SSF47413 11 75 1.01E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS08405 a0fef60d25a68aa93cbfd985bf6f5795 84 Gene3D G3DSA:1.10.260.40 10 76 3.7E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS01265 d83cfcfea46efc21ab9d28743371e1ca 164 Gene3D G3DSA:3.40.1280.10 7 164 4.0E-40 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MED134_RS01265 d83cfcfea46efc21ab9d28743371e1ca 164 PANTHER PTHR12029 17 164 1.8E-35 T 22-04-2016 MED134_RS01265 d83cfcfea46efc21ab9d28743371e1ca 164 SUPERFAMILY SSF75217 11 164 2.68E-35 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases MED134_RS01265 d83cfcfea46efc21ab9d28743371e1ca 164 Pfam PF00588 SpoU rRNA Methylase family 17 160 1.4E-32 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MED134_RS03315 0c868062e03eb6c17b9d1818e55b22db 499 SUPERFAMILY SSF53474 24 473 7.87E-74 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03315 0c868062e03eb6c17b9d1818e55b22db 499 Gene3D G3DSA:3.40.50.1820 39 452 8.5E-48 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03315 0c868062e03eb6c17b9d1818e55b22db 499 Pfam PF00450 Serine carboxypeptidase 66 271 1.6E-12 T 22-04-2016 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815 301 571 1.9E-50 T 22-04-2016 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815:SF13 672 823 1.9E-50 T 22-04-2016 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815:SF13 301 571 1.9E-50 T 22-04-2016 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 Pfam PF01103 Surface antigen 491 831 5.3E-23 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815:SF13 113 259 1.9E-50 T 22-04-2016 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 Pfam PF07244 Surface antigen variable number repeat 134 180 1.3E-4 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815 672 823 1.9E-50 T 22-04-2016 MED134_RS05505 59830525a6c0e7e9bd04902183157ef6 856 PANTHER PTHR12815 113 259 1.9E-50 T 22-04-2016 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 SUPERFAMILY SSF53633 1 234 5.24E-69 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 Hamap MF_01220_B Uridylate kinase [pyrH]. 1 235 45.336 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 PANTHER PTHR21499 1 234 2.5E-112 T 22-04-2016 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 PANTHER PTHR21499:SF23 1 234 2.5E-112 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 3 234 6.6E-103 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 PIRSF PIRSF005650 1 235 3.7E-94 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 Pfam PF00696 Amino acid kinase family 4 213 1.1E-28 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS06820 a392be91b439ad578805be9b62532be3 235 Gene3D G3DSA:3.40.1160.10 1 234 1.5E-84 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 MED134_RS14000 f3dc38d5d9a7272faca76df16de9e77b 96 Pfam PF04359 Protein of unknown function (DUF493) 24 94 6.0E-9 T 22-04-2016 IPR007454 Uncharacterised protein family UPF0250 MED134_RS14000 f3dc38d5d9a7272faca76df16de9e77b 96 SUPERFAMILY SSF117991 15 94 1.44E-18 T 22-04-2016 IPR027471 YbeD-like domain MED134_RS14000 f3dc38d5d9a7272faca76df16de9e77b 96 Gene3D G3DSA:3.30.70.1460 16 95 2.7E-17 T 22-04-2016 IPR027471 YbeD-like domain MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 Gene3D G3DSA:3.40.50.620 2 146 2.4E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 PRINTS PR01438 Universal stress protein signature 124 146 4.2E-12 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 PRINTS PR01438 Universal stress protein signature 106 118 4.2E-12 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 PRINTS PR01438 Universal stress protein signature 1 18 4.2E-12 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 SUPERFAMILY SSF52402 156 276 6.2E-9 T 22-04-2016 MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 Pfam PF00582 Universal stress protein family 1 143 3.7E-16 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 Gene3D G3DSA:3.40.50.620 169 275 1.8E-4 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 PANTHER PTHR31964 1 146 9.6E-16 T 22-04-2016 MED134_RS04640 b048fa0d52bb614af529de81474b01bb 281 SUPERFAMILY SSF52402 2 158 3.77E-26 T 22-04-2016 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 PANTHER PTHR30154 2 134 2.3E-38 T 22-04-2016 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 Gene3D G3DSA:3.30.70.920 55 125 5.5E-16 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 SUPERFAMILY SSF46785 1 62 2.14E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 PANTHER PTHR30154:SF2 2 134 2.3E-38 T 22-04-2016 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 1.9E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 4.4E-13 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.4E-13 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.4E-13 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 Gene3D G3DSA:1.10.10.10 3 54 1.6E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 Pfam PF01037 Lrp/AsnC ligand binding domain 75 134 1.1E-12 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 SUPERFAMILY SSF54909 64 137 6.43E-15 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 SMART SM00344 2 108 5.3E-34 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MED134_RS03420 ea816c9927431fd68cb100e387934e5d 144 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 SUPERFAMILY SSF51316 31 158 1.36E-52 T 22-04-2016 IPR011057 Mss4-like MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 Gene3D G3DSA:2.170.150.20 27 158 2.2E-54 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 PANTHER PTHR10173 20 156 2.7E-50 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 PANTHER PTHR10173:SF18 20 156 2.7E-50 T 22-04-2016 MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 33 158 1.1E-46 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS04480 dcb6a50bdd82faab00b6e5d265044703 159 Pfam PF01641 SelR domain 37 156 6.9E-48 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 MED134_RS11435 169f86a6e4236d754e8cba08c3f055be 146 PANTHER PTHR30373 10 142 1.2E-18 T 22-04-2016 MED134_RS11435 169f86a6e4236d754e8cba08c3f055be 146 PANTHER PTHR30373:SF3 10 142 1.2E-18 T 22-04-2016 MED134_RS11435 169f86a6e4236d754e8cba08c3f055be 146 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 6 119 5.3E-23 T 22-04-2016 IPR007621 TPM domain MED134_RS09675 345489116e91c095e0b0688b024dc648 178 SUPERFAMILY SSF51182 1 171 2.65E-55 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS09675 345489116e91c095e0b0688b024dc648 178 PANTHER PTHR15497 3 178 1.2E-72 T 22-04-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 MED134_RS09675 345489116e91c095e0b0688b024dc648 178 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 7 167 5.1E-62 T 22-04-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 MED134_RS09675 345489116e91c095e0b0688b024dc648 178 Gene3D G3DSA:2.60.120.10 6 111 1.7E-21 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS09675 345489116e91c095e0b0688b024dc648 178 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 3 172 34.917 T 22-04-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 MED134_RS09675 345489116e91c095e0b0688b024dc648 178 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 3 154 4.9E-54 T 22-04-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 MED134_RS04185 43c030a10b23433b817e50f0539bb926 206 Gene3D G3DSA:2.50.20.10 22 195 4.1E-15 T 22-04-2016 MED134_RS04185 43c030a10b23433b817e50f0539bb926 206 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 76 194 1.6E-9 T 22-04-2016 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MED134_RS04185 43c030a10b23433b817e50f0539bb926 206 SUPERFAMILY SSF89392 22 199 2.43E-14 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX MED134_RS07250 f317235a7dee01508974d8ddf67ff831 93 Pfam PF04248 Domain of unknown function (DUF427) 1 87 8.2E-30 T 22-04-2016 IPR007361 Domain of unknown function DUF427 MED134_RS07250 f317235a7dee01508974d8ddf67ff831 93 PANTHER PTHR34310:SF1 1 93 6.6E-39 T 22-04-2016 MED134_RS07250 f317235a7dee01508974d8ddf67ff831 93 PANTHER PTHR34310 1 93 6.6E-39 T 22-04-2016 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 Pfam PF00155 Aminotransferase class I and II 32 387 1.0E-69 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 Gene3D G3DSA:3.40.640.10 45 272 3.2E-72 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 Gene3D G3DSA:3.90.1150.10 273 393 6.7E-41 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 SUPERFAMILY SSF53383 1 393 1.32E-110 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 PANTHER PTHR11751 14 393 2.7E-157 T 22-04-2016 MED134_RS12420 e2d1dd62ffd06cdac903e2258dc1f11e 394 PANTHER PTHR11751:SF306 14 393 2.7E-157 T 22-04-2016 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 PANTHER PTHR10362 6 502 4.2E-219 T 22-04-2016 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 10 488 1.2E-184 T 22-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 157 - T 22-04-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 SUPERFAMILY SSF48557 2 495 5.96E-186 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 Gene3D G3DSA:1.20.200.10 200 493 2.9E-116 T 22-04-2016 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 PANTHER PTHR10362:SF7 6 502 4.2E-219 T 22-04-2016 MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 Gene3D G3DSA:1.10.275.10 3 199 9.0E-69 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal MED134_RS01990 59cb9f3370ece8fa8385ffabb992144a 502 Pfam PF00221 Aromatic amino acid lyase 13 468 1.6E-182 T 22-04-2016 IPR001106 Aromatic amino acid lyase MED134_RS08500 06438766cba08988f028989e95e76c06 550 Pfam PF07394 Protein of unknown function (DUF1501) 278 426 5.6E-26 T 22-04-2016 IPR010869 Protein of unknown function DUF1501 MED134_RS12740 1018d33b417bf133bbd956a985747443 205 PIRSF PIRSF010372 1 205 1.1E-64 T 22-04-2016 IPR007396 Transcriptional regulator PAI 2-type MED134_RS12740 1018d33b417bf133bbd956a985747443 205 Pfam PF04299 Putative FMN-binding domain 1 160 4.6E-45 T 22-04-2016 IPR007396 Transcriptional regulator PAI 2-type MED134_RS12740 1018d33b417bf133bbd956a985747443 205 PANTHER PTHR35802:SF1 2 200 1.4E-49 T 22-04-2016 MED134_RS12740 1018d33b417bf133bbd956a985747443 205 SUPERFAMILY SSF50475 12 187 3.54E-32 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS12740 1018d33b417bf133bbd956a985747443 205 Gene3D G3DSA:2.30.110.10 1 200 5.8E-58 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS12740 1018d33b417bf133bbd956a985747443 205 PANTHER PTHR35802 2 200 1.4E-49 T 22-04-2016 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 SMART SM00448 1 110 6.2E-14 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 Gene3D G3DSA:2.40.50.40 138 206 2.0E-21 T 22-04-2016 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 SMART SM00850 146 237 1.4E-27 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 Pfam PF04397 LytTr DNA-binding domain 147 236 5.7E-21 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 SUPERFAMILY SSF52172 2 122 1.99E-22 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 Pfam PF00072 Response regulator receiver domain 4 110 5.4E-17 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 PANTHER PTHR26402 1 113 2.6E-22 T 22-04-2016 MED134_RS00620 e7a0912eb6ba49811ca2de481699436f 239 Gene3D G3DSA:3.40.50.2300 2 114 1.9E-22 T 22-04-2016 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Gene3D G3DSA:1.10.8.60 378 444 9.9E-25 T 22-04-2016 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Gene3D G3DSA:3.40.50.300 195 377 2.9E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Pfam PF06480 FtsH Extracellular 23 133 5.1E-6 T 22-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 142 635 2.1E-214 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 ProSitePatterns PS00674 AAA-protein family signature. 339 357 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 368 8.2E-45 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 SUPERFAMILY SSF140990 451 643 3.01E-63 T 22-04-2016 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 SUPERFAMILY SSF52540 196 468 6.42E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 SMART SM00382 231 371 1.9E-22 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 19 647 34.079 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 PANTHER PTHR23076:SF10 3 648 0.0 T 22-04-2016 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 Pfam PF01434 Peptidase family M41 432 634 2.4E-71 T 22-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 MED134_RS05855 af5559e42f8d01aca810ea685097b205 651 PANTHER PTHR23076 3 648 0.0 T 22-04-2016 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 PANTHER PTHR30308 5 153 1.2E-59 T 22-04-2016 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 Pfam PF01668 SmpB protein 7 69 7.7E-27 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 ProSitePatterns PS01317 SsrA-binding protein. 24 36 - T 22-04-2016 IPR020081 SsrA-binding protein, conserved site MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 PANTHER PTHR30308:SF2 5 153 1.2E-59 T 22-04-2016 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 Gene3D G3DSA:2.40.280.10 5 126 1.2E-46 T 22-04-2016 IPR023620 Small protein B MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 TIGRFAM TIGR00086 smpB: SsrA-binding protein 6 147 3.2E-54 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 8 131 2.0E-28 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 Hamap MF_00023 SsrA-binding protein [smpB]. 1 153 61.375 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 MED134_RS04225 6eaf3ee8d0d235915755814242daf259 153 SUPERFAMILY SSF74982 4 131 7.59E-43 T 22-04-2016 IPR023620 Small protein B MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 PRINTS PR01438 Universal stress protein signature 108 120 1.3E-11 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 PRINTS PR01438 Universal stress protein signature 1 17 1.3E-11 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 PRINTS PR01438 Universal stress protein signature 126 148 1.3E-11 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 SUPERFAMILY SSF52402 1 159 3.52E-25 T 22-04-2016 MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 SUPERFAMILY SSF52402 156 281 2.34E-10 T 22-04-2016 MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 Pfam PF00582 Universal stress protein family 1 147 1.7E-15 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 Gene3D G3DSA:3.40.50.620 223 281 7.3E-6 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 Gene3D G3DSA:3.40.50.620 1 148 3.7E-23 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04635 b7dd2bb5383640edb4985c5424b84056 282 PANTHER PTHR31964 1 168 7.4E-16 T 22-04-2016 MED134_RS13330 97625c45c8a62d2fdcc9aeda94d3cb90 261 Pfam PF13578 Methyltransferase domain 114 215 8.6E-14 T 22-04-2016 MED134_RS13330 97625c45c8a62d2fdcc9aeda94d3cb90 261 Gene3D G3DSA:3.40.50.150 94 252 4.3E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13330 97625c45c8a62d2fdcc9aeda94d3cb90 261 SUPERFAMILY SSF53335 92 252 7.21E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 PANTHER PTHR11699 2 450 1.5E-219 T 22-04-2016 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 SUPERFAMILY SSF53720 3 451 1.96E-140 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 Gene3D G3DSA:3.40.605.10 3 242 1.6E-72 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 Pfam PF00171 Aldehyde dehydrogenase family 3 448 6.4E-137 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 PANTHER PTHR11699:SF28 2 450 1.5E-219 T 22-04-2016 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 Gene3D G3DSA:3.40.309.10 243 424 6.2E-60 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 MED134_RS02835 b3a5fcc0c89bd3e1b25ca450076ba07d 451 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 255 266 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MED134_RS05015 30c9314c37030890d3909b6b5f84eb08 282 Gene3D G3DSA:1.20.144.10 87 252 3.9E-25 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS05015 30c9314c37030890d3909b6b5f84eb08 282 Pfam PF01569 PAP2 superfamily 139 241 2.3E-12 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS05015 30c9314c37030890d3909b6b5f84eb08 282 SUPERFAMILY SSF48317 74 250 5.89E-22 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS02320 85f599a8511051df47934f0f8f2aabcb 373 Gene3D G3DSA:3.40.50.410 182 338 1.6E-4 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS02320 85f599a8511051df47934f0f8f2aabcb 373 SUPERFAMILY SSF53300 183 350 3.02E-15 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 15 255 3.0E-55 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 272 19.138 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PANTHER PTHR30371 11 57 8.3E-72 T 22-04-2016 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PANTHER PTHR30371 79 272 8.3E-72 T 22-04-2016 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 Pfam PF00902 Sec-independent protein translocase protein (TatC) 16 250 6.9E-66 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 131 157 8.3E-35 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 8.3E-35 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 113 131 8.3E-35 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS05000 797b9279b17698b5d3cc55938df1f38d 279 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 183 211 8.3E-35 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 Gene3D G3DSA:1.10.10.10 10 149 3.0E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 SUPERFAMILY SSF46785 13 150 1.76E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 SMART SM00347 35 137 1.5E-20 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 3.2E-9 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 127 147 3.2E-9 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 3.2E-9 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 Pfam PF01047 MarR family 42 101 2.8E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 PANTHER PTHR33164 37 147 2.3E-22 T 22-04-2016 MED134_RS13065 9305717183e95d9febb5f8c4040391cc 153 PANTHER PTHR33164:SF4 37 147 2.3E-22 T 22-04-2016 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 PIRSF PIRSF020736 1 193 2.5E-48 T 22-04-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 4 43 1.8E-6 T 22-04-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 46 192 1.1E-27 T 22-04-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 SUPERFAMILY SSF47240 1 193 3.29E-67 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 PANTHER PTHR42637:SF1 1 192 7.9E-24 T 22-04-2016 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 PANTHER PTHR42637 1 192 7.9E-24 T 22-04-2016 MED134_RS00900 1b7b11f81da8ab52e0ab3f45c5d746fd 193 Gene3D G3DSA:1.20.1260.10 2 193 2.5E-64 T 22-04-2016 IPR012347 Ferritin-related MED134_RS02245 904fd18d1ea6c9ca61e6e2d341bbcc0e 313 Pfam PF03631 Virulence factor BrkB 54 304 2.7E-49 T 22-04-2016 IPR017039 Virulence factor BrkB MED134_RS02245 904fd18d1ea6c9ca61e6e2d341bbcc0e 313 PANTHER PTHR30213 10 306 5.7E-38 T 22-04-2016 MED134_RS02245 904fd18d1ea6c9ca61e6e2d341bbcc0e 313 PIRSF PIRSF035875 35 313 1.1E-47 T 22-04-2016 IPR017039 Virulence factor BrkB MED134_RS02245 904fd18d1ea6c9ca61e6e2d341bbcc0e 313 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 53 304 4.1E-27 T 22-04-2016 IPR017039 Virulence factor BrkB MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 6 279 50.92 T 22-04-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 PANTHER PTHR11941 1 273 2.6E-159 T 22-04-2016 MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 Gene3D G3DSA:3.90.226.10 7 216 4.0E-65 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 Gene3D G3DSA:1.10.12.10 219 268 8.8E-28 T 22-04-2016 IPR014748 Crontonase, C-terminal MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 TIGRFAM TIGR01929 menB: naphthoate synthase 12 275 8.4E-124 T 22-04-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 SUPERFAMILY SSF52096 6 275 3.65E-76 T 22-04-2016 IPR029045 ClpP/crotonase-like domain MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 PANTHER PTHR11941:SF20 1 273 2.6E-159 T 22-04-2016 MED134_RS13780 ceb465591a906dcbd9f69eae94ab4c24 279 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 275 4.3E-60 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 202 3.4E-27 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 Gene3D G3DSA:3.30.950.10 112 223 1.4E-40 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 81 92 - T 22-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 221 35.877 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 PIRSF PIRSF005917 1 224 1.2E-91 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 SUPERFAMILY SSF53790 2 219 1.44E-79 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 PANTHER PTHR21091 1 221 1.2E-88 T 22-04-2016 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 PANTHER PTHR21091:SF18 1 221 1.2E-88 T 22-04-2016 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 221 4.0E-71 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS09825 b4179a73861b5f57d8fe8825c234453d 224 Gene3D G3DSA:3.40.1010.10 3 111 7.3E-17 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 Gene3D G3DSA:3.40.390.10 405 473 1.1E-8 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 SUPERFAMILY SSF55486 205 471 3.18E-27 T 22-04-2016 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 Pfam PF16313 Met-zincin 396 702 1.4E-68 T 22-04-2016 IPR032534 Domian of unknown function DUF4953 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 Pfam PF17162 Domain of unknown function (DUF5118) 25 63 2.8E-8 T 22-04-2016 IPR033428 Domain of unknown function DUF5118 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 Pfam PF17148 Domain of unknown function (DUF5117) 77 269 1.0E-44 T 22-04-2016 IPR033413 Domain of unknown function DUF5117 MED134_RS14245 3247a6b29befb5d2e5d890425b5b00e2 797 PANTHER PTHR38478 22 771 5.7E-117 T 22-04-2016 MED134_RS13465 00f4bfc36aafaff501648b23bf53b69b 357 SUPERFAMILY SSF53756 5 356 1.88E-55 T 22-04-2016 MED134_RS13465 00f4bfc36aafaff501648b23bf53b69b 357 PANTHER PTHR12526 1 357 1.7E-44 T 22-04-2016 MED134_RS13465 00f4bfc36aafaff501648b23bf53b69b 357 Pfam PF13439 Glycosyltransferase Family 4 12 122 1.1E-13 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS13465 00f4bfc36aafaff501648b23bf53b69b 357 Pfam PF00534 Glycosyl transferases group 1 170 320 3.7E-26 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS13465 00f4bfc36aafaff501648b23bf53b69b 357 Gene3D G3DSA:3.40.50.2000 176 321 1.4E-11 T 22-04-2016 MED134_RS05275 6de928498c6838ece5eb16c5a32f57e9 289 SUPERFAMILY SSF103481 207 288 9.94E-6 T 22-04-2016 MED134_RS05275 6de928498c6838ece5eb16c5a32f57e9 289 SUPERFAMILY SSF103481 51 134 6.8E-8 T 22-04-2016 MED134_RS05275 6de928498c6838ece5eb16c5a32f57e9 289 Pfam PF00892 EamA-like transporter family 2 133 4.5E-8 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 PIRSF PIRSF006621 2 315 6.6E-43 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 PANTHER PTHR11082 9 311 2.5E-68 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 Pfam PF01207 Dihydrouridine synthase (Dus) 8 259 4.3E-28 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 SUPERFAMILY SSF51395 5 304 6.01E-36 T 22-04-2016 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 PANTHER PTHR11082:SF32 9 311 2.5E-68 T 22-04-2016 MED134_RS01125 b1ad18430bd9bf534de03e8e898d597d 315 Gene3D G3DSA:3.20.20.70 5 237 1.3E-39 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 SUPERFAMILY SSF54826 3 100 2.04E-16 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 Pfam PF13378 Enolase C-terminal domain-like 131 332 1.5E-23 T 22-04-2016 IPR029065 Enolase C-terminal domain-like MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 Gene3D G3DSA:3.20.20.120 114 335 2.7E-60 T 22-04-2016 IPR029065 Enolase C-terminal domain-like MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 SMART SM00922 128 226 2.9E-15 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 Gene3D G3DSA:3.30.390.10 1 100 3.9E-34 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 PANTHER PTHR13794 10 334 3.2E-69 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 SUPERFAMILY SSF51604 114 336 8.78E-51 T 22-04-2016 IPR029065 Enolase C-terminal domain-like MED134_RS04535 bc307f48dade2092b33a0e192be71ee5 344 PANTHER PTHR13794:SF8 10 334 3.2E-69 T 22-04-2016 IPR010197 o-succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00079|UniPathway: UPA01057 MED134_RS03225 028075ae041c8c56a1f165c3fee249fa 356 Gene3D G3DSA:2.130.10.10 82 352 8.5E-18 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS03225 028075ae041c8c56a1f165c3fee249fa 356 SUPERFAMILY SSF51004 84 352 2.88E-17 T 22-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 7 223 4.9E-57 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Pfam PF07977 FabA-like domain 333 456 1.6E-30 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 SUPERFAMILY SSF54211 7 128 2.12E-36 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 PANTHER PTHR30272:SF1 259 466 1.5E-93 T 22-04-2016 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 SUPERFAMILY SSF54211 144 302 3.64E-35 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 325 461 4.4E-49 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 8 302 1.3E-88 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 PANTHER PTHR30272 259 466 1.5E-93 T 22-04-2016 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 SUPERFAMILY SSF54637 326 463 7.47E-43 T 22-04-2016 IPR029069 HotDog domain MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Gene3D G3DSA:3.10.129.10 322 464 5.0E-53 T 22-04-2016 IPR029069 HotDog domain MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 324 464 30.722 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Gene3D G3DSA:3.30.1700.10 134 306 4.9E-47 T 22-04-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 MED134_RS02510 9594a7f7a296345744c747a2b37dcca4 468 Gene3D G3DSA:3.30.230.20 7 129 1.2E-41 T 22-04-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 MED134_RS14030 7f8731ff5d833353dced4689bc17d94f 235 SUPERFAMILY SSF100950 1 235 2.09E-65 T 22-04-2016 MED134_RS14030 7f8731ff5d833353dced4689bc17d94f 235 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 9 234 6.6E-61 T 22-04-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31|UniPathway: UPA00115 MED134_RS14030 7f8731ff5d833353dced4689bc17d94f 235 PANTHER PTHR11054 2 231 2.1E-71 T 22-04-2016 MED134_RS14030 7f8731ff5d833353dced4689bc17d94f 235 Gene3D G3DSA:3.40.50.1360 1 233 2.5E-75 T 22-04-2016 MED134_RS14030 7f8731ff5d833353dced4689bc17d94f 235 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 225 1.9E-64 T 22-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 PIRSF PIRSF000498 1 195 7.0E-67 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 191 3.0E-61 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 Gene3D G3DSA:2.40.30.20 103 193 1.3E-29 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 Gene3D G3DSA:2.40.30.20 5 102 2.6E-31 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 PANTHER PTHR21098 1 195 3.9E-85 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 Pfam PF00677 Lumazine binding domain 3 85 6.6E-20 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 Pfam PF00677 Lumazine binding domain 98 182 1.4E-22 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 SUPERFAMILY SSF63380 1 91 4.0E-25 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS06705 d666b5f836ec741fc46b607726ec9044 195 SUPERFAMILY SSF63380 91 193 1.96E-30 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MED134_RS11925 3b94e64a8ce7d131cbeffe9533229c99 496 Pfam PF04087 Domain of unknown function (DUF389) 97 240 4.4E-34 T 22-04-2016 IPR005240 Protein of unknown function DUF389 MED134_RS11925 3b94e64a8ce7d131cbeffe9533229c99 496 PANTHER PTHR20992:SF9 21 281 7.6E-51 T 22-04-2016 MED134_RS11925 3b94e64a8ce7d131cbeffe9533229c99 496 PANTHER PTHR20992 21 281 7.6E-51 T 22-04-2016 MED134_RS07175 4fedfcd806b2f2d5c2e034c262da664a 335 PANTHER PTHR28208 52 314 2.1E-55 T 22-04-2016 MED134_RS07175 4fedfcd806b2f2d5c2e034c262da664a 335 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 197 292 9.3E-34 T 22-04-2016 IPR019236 Domain of unknown function DUF2183 MED134_RS07175 4fedfcd806b2f2d5c2e034c262da664a 335 PANTHER PTHR28208:SF3 52 314 2.1E-55 T 22-04-2016 MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 SMART SM00450 35 132 1.9E-21 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 Gene3D G3DSA:3.40.250.10 30 142 2.4E-30 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 PANTHER PTHR12231 47 130 1.5E-13 T 22-04-2016 MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 ProSitePatterns PS00380 Rhodanese signature 1. 60 71 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 SUPERFAMILY SSF52821 29 139 1.83E-28 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06560 eff7129a4d1befd0df4c9023804c3f47 162 Pfam PF00581 Rhodanese-like domain 39 128 5.7E-16 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 PANTHER PTHR30203:SF1 22 394 5.7E-26 T 22-04-2016 MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 PANTHER PTHR30203 22 394 5.7E-26 T 22-04-2016 MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 Gene3D G3DSA:1.20.1600.10 14 403 1.2E-44 T 22-04-2016 MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 SUPERFAMILY SSF56954 2 404 3.27E-59 T 22-04-2016 MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 Pfam PF02321 Outer membrane efflux protein 22 200 4.2E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS00745 a1853f45daffdfcdd83cffd22ea47a6d 406 Pfam PF02321 Outer membrane efflux protein 225 405 3.2E-20 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 Gene3D G3DSA:3.40.390.10 280 521 5.4E-16 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 Pfam PF17162 Domain of unknown function (DUF5118) 50 97 1.6E-19 T 22-04-2016 IPR033428 Domain of unknown function DUF5118 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 PANTHER PTHR38478 56 831 2.2E-145 T 22-04-2016 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 SUPERFAMILY SSF55486 241 521 5.5E-23 T 22-04-2016 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 Pfam PF17148 Domain of unknown function (DUF5117) 110 298 1.7E-60 T 22-04-2016 IPR033413 Domain of unknown function DUF5117 MED134_RS03520 1fd1e4aa1dea38b73dc54f334867f3f3 832 Pfam PF16313 Met-zincin 432 736 1.5E-105 T 22-04-2016 IPR032534 Domian of unknown function DUF4953 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 PIRSF PIRSF037489 1 364 8.5E-115 T 22-04-2016 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 PANTHER PTHR13799:SF13 155 364 1.9E-106 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 PANTHER PTHR13799:SF13 1 133 1.9E-106 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 359 1.0E-52 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 Gene3D G3DSA:3.30.70.830 130 234 4.6E-35 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 Gene3D G3DSA:3.40.1390.30 1 113 1.1E-44 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 347 1.1E-72 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 SUPERFAMILY SSF102705 1 363 2.35E-119 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 Gene3D G3DSA:3.40.1390.30 236 326 1.6E-30 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 Gene3D G3DSA:3.40.1390.30 114 129 1.6E-30 T 22-04-2016 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 PANTHER PTHR13799 155 364 1.9E-106 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MED134_RS05890 6eb6e11010877dc048ae85430e3fed36 364 PANTHER PTHR13799 1 133 1.9E-106 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 6.8E-56 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 SMART SM01374 1 122 6.4E-88 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 22-04-2016 IPR019972 Ribosomal protein L14P, conserved site MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 Gene3D G3DSA:2.40.150.20 1 122 4.8E-54 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 SUPERFAMILY SSF50193 1 122 6.28E-51 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.821 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.6E-57 T 22-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12285 613a78375189d9e01f4da32f666ced6c 122 PANTHER PTHR11761 1 122 2.8E-77 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 PANTHER PTHR40114 1 155 4.1E-42 T 22-04-2016 MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 SMART SM01118 1 148 4.1E-24 T 22-04-2016 IPR023577 CYTH domain MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 SUPERFAMILY SSF55154 1 150 4.91E-42 T 22-04-2016 IPR033469 CYTH-like domain MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 Pfam PF01928 CYTH domain 1 139 8.9E-14 T 22-04-2016 IPR023577 CYTH domain MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 Gene3D G3DSA:2.40.320.10 2 152 1.4E-54 T 22-04-2016 IPR023577 CYTH domain MED134_RS10395 fb8f938d4563a0b397d09da8fdb2ad1c 155 PIRSF PIRSF016487 1 155 2.8E-57 T 22-04-2016 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like MED134_RS14675 b98f1c0f960494f2aa0e9384671f2eb2 364 Pfam PF14175 YaaC-like Protein 31 349 1.1E-55 T 22-04-2016 IPR026988 YaaC-like protein MED134_RS06760 b105cdf5558e0f75f8b33af6e69edf66 233 Gene3D G3DSA:3.20.20.380 1 232 6.0E-81 T 22-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 MED134_RS06760 b105cdf5558e0f75f8b33af6e69edf66 233 PANTHER PTHR12598 1 200 5.4E-85 T 22-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 MED134_RS06760 b105cdf5558e0f75f8b33af6e69edf66 233 SUPERFAMILY SSF110395 1 199 9.29E-64 T 22-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 MED134_RS06760 b105cdf5558e0f75f8b33af6e69edf66 233 PANTHER PTHR12598:SF0 1 200 5.4E-85 T 22-04-2016 MED134_RS06760 b105cdf5558e0f75f8b33af6e69edf66 233 Pfam PF03932 CutC family 1 200 1.4E-72 T 22-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 SUPERFAMILY SSF81452 255 324 9.68E-19 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 Gene3D G3DSA:1.20.120.80 21 143 3.9E-57 T 22-04-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 Gene3D G3DSA:1.20.120.80 256 325 3.9E-57 T 22-04-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 PANTHER PTHR11403 29 142 3.6E-27 T 22-04-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 PANTHER PTHR11403 255 325 3.6E-27 T 22-04-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 Pfam PF00510 Cytochrome c oxidase subunit III 258 324 8.6E-8 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 MED134_RS11330 a0b34ea53f52eac6bd5d16a920eb99b6 325 SUPERFAMILY SSF81452 12 135 4.97E-19 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 MED134_RS02490 7064f3e7b94cb5bd3f1e2f99e246e4c2 133 Gene3D G3DSA:3.10.450.50 1 120 2.2E-9 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS02490 7064f3e7b94cb5bd3f1e2f99e246e4c2 133 SUPERFAMILY SSF54427 2 116 6.39E-15 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS02490 7064f3e7b94cb5bd3f1e2f99e246e4c2 133 Pfam PF12680 SnoaL-like domain 19 112 2.1E-8 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain MED134_RS09270 73537b66bd10739dea59f2d5a4802e05 409 Pfam PF04932 O-Antigen ligase 201 345 1.2E-11 T 22-04-2016 IPR007016 O-antigen ligase-related MED134_RS08740 862a3a3efd7317fc1b8cc31aa53392fe 574 Pfam PF13687 Domain of unknown function (DUF4153) 149 371 2.0E-52 T 22-04-2016 IPR025291 Protein of unknown function DUF4153 MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Gene3D G3DSA:2.30.180.10 175 315 1.8E-23 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Gene3D G3DSA:2.30.180.10 38 172 5.5E-28 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SMART SM00554 361 466 5.2E-13 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SMART SM00554 73 176 1.4E-18 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SMART SM00554 214 319 8.0E-17 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 PANTHER PTHR10900 241 463 7.3E-51 T 22-04-2016 MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 PANTHER PTHR10900 39 175 7.3E-51 T 22-04-2016 MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SUPERFAMILY SSF82153 319 463 3.53E-20 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SUPERFAMILY SSF82153 39 176 1.57E-26 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Gene3D G3DSA:2.30.180.10 319 463 6.9E-23 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Pfam PF02469 Fasciclin domain 187 315 3.5E-20 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Pfam PF02469 Fasciclin domain 328 463 6.8E-16 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 Pfam PF02469 Fasciclin domain 49 172 1.4E-24 T 22-04-2016 IPR000782 FAS1 domain MED134_RS03365 1ad1b9bd70c4b071554ed9b28a422868 466 SUPERFAMILY SSF82153 176 320 3.79E-23 T 22-04-2016 IPR000782 FAS1 domain MED134_RS11015 455869296d8e7448b410552e5621659c 745 SUPERFAMILY SSF109755 575 717 5.76E-5 T 22-04-2016 MED134_RS11015 455869296d8e7448b410552e5621659c 745 Pfam PF01384 Phosphate transporter family 26 341 7.0E-31 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 MED134_RS11015 455869296d8e7448b410552e5621659c 745 PANTHER PTHR11101 403 710 6.5E-19 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 MED134_RS11015 455869296d8e7448b410552e5621659c 745 PANTHER PTHR11101 1 86 6.5E-19 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 MED134_RS11015 455869296d8e7448b410552e5621659c 745 PANTHER PTHR11101:SF16 403 710 6.5E-19 T 22-04-2016 MED134_RS11015 455869296d8e7448b410552e5621659c 745 PANTHER PTHR11101:SF16 1 86 6.5E-19 T 22-04-2016 MED134_RS12870 874965b467c71299923fd94afefae61a 330 Gene3D G3DSA:3.40.50.720 5 167 2.0E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12870 874965b467c71299923fd94afefae61a 330 PANTHER PTHR10366 4 327 4.8E-81 T 22-04-2016 MED134_RS12870 874965b467c71299923fd94afefae61a 330 Gene3D G3DSA:3.90.25.10 168 310 6.7E-30 T 22-04-2016 MED134_RS12870 874965b467c71299923fd94afefae61a 330 SUPERFAMILY SSF51735 6 312 3.61E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12870 874965b467c71299923fd94afefae61a 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 239 5.0E-56 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 MED134_RS08745 598f7bcb7d7afceb063f55b601487d94 238 SUPERFAMILY SSF53098 9 227 1.75E-33 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08745 598f7bcb7d7afceb063f55b601487d94 238 Gene3D G3DSA:3.30.420.10 60 223 3.7E-24 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08745 598f7bcb7d7afceb063f55b601487d94 238 Gene3D G3DSA:3.30.420.10 10 26 3.7E-24 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS08745 598f7bcb7d7afceb063f55b601487d94 238 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 62 223 6.7E-15 T 22-04-2016 IPR019288 Predicted 3'-5' exonuclease, PolB-like MED134_RS12460 603c8535f73764930fe28cc757b90fd2 262 PANTHER PTHR23090 4 212 1.2E-48 T 22-04-2016 MED134_RS12460 603c8535f73764930fe28cc757b90fd2 262 Pfam PF02540 NAD synthase 7 240 1.4E-50 T 22-04-2016 IPR022310 NAD/GMP synthase MED134_RS12460 603c8535f73764930fe28cc757b90fd2 262 SUPERFAMILY SSF52402 3 255 9.54E-62 T 22-04-2016 MED134_RS12460 603c8535f73764930fe28cc757b90fd2 262 Gene3D G3DSA:3.40.50.620 2 255 1.0E-68 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS12460 603c8535f73764930fe28cc757b90fd2 262 TIGRFAM TIGR00552 nadE: NAD+ synthetase 4 240 2.6E-54 T 22-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 MED134_RS13260 a11bc641462d58c38c20315db4d6111c 189 SUPERFAMILY SSF48317 4 182 1.01E-31 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS13260 a11bc641462d58c38c20315db4d6111c 189 SMART SM00014 59 175 5.7E-19 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS13260 a11bc641462d58c38c20315db4d6111c 189 Gene3D G3DSA:1.20.144.10 4 179 4.4E-27 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS13260 a11bc641462d58c38c20315db4d6111c 189 Pfam PF01569 PAP2 superfamily 61 180 2.8E-25 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS13260 a11bc641462d58c38c20315db4d6111c 189 PANTHER PTHR14969 1 175 3.7E-18 T 22-04-2016 MED134_RS11070 c86681aa990cbfa50953b320bf0be878 207 PANTHER PTHR30558 113 145 3.3E-13 T 22-04-2016 MED134_RS11070 c86681aa990cbfa50953b320bf0be878 207 PANTHER PTHR30558 1 89 3.3E-13 T 22-04-2016 MED134_RS11070 c86681aa990cbfa50953b320bf0be878 207 Pfam PF02472 Biopolymer transport protein ExbD/TolR 3 145 2.0E-19 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MED134_RS01485 8e491e85b45e3f209249d5ca381a7e9f 123 Gene3D G3DSA:1.10.8.290 6 122 1.1E-49 T 22-04-2016 IPR023204 SP1917 domain MED134_RS01485 8e491e85b45e3f209249d5ca381a7e9f 123 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 10 121 6.8E-48 T 22-04-2016 IPR014580 Uncharacterised conserved protein UCP033199 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 PANTHER PTHR11669:SF8 133 248 3.2E-47 T 22-04-2016 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 PANTHER PTHR11669:SF8 1 88 3.2E-47 T 22-04-2016 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 SUPERFAMILY SSF52540 3 84 2.75E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 SUPERFAMILY SSF52540 126 248 2.75E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 Pfam PF13177 DNA polymerase III, delta subunit 9 210 1.8E-41 T 22-04-2016 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 Gene3D G3DSA:1.10.8.60 201 248 2.5E-5 T 22-04-2016 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 Gene3D G3DSA:3.40.50.300 3 83 1.8E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 Gene3D G3DSA:3.40.50.300 125 200 1.8E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 PANTHER PTHR11669 133 248 3.2E-47 T 22-04-2016 MED134_RS09190 2e94fd35408f44cb0138fbd6a3b9b091 383 PANTHER PTHR11669 1 88 3.2E-47 T 22-04-2016 MED134_RS02615 4cc00203165ff03195e2aad8e897cf20 81 Gene3D G3DSA:1.10.1200.10 7 79 2.5E-16 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS02615 4cc00203165ff03195e2aad8e897cf20 81 Pfam PF00550 Phosphopantetheine attachment site 21 73 7.5E-7 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS02615 4cc00203165ff03195e2aad8e897cf20 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 44 80 0.008 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 MED134_RS02615 4cc00203165ff03195e2aad8e897cf20 81 SUPERFAMILY SSF47336 6 79 5.63E-14 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain MED134_RS09710 eaea0e58e20fb27b0c8d7fc7b2f7b786 267 Gene3D G3DSA:3.40.50.720 3 214 1.9E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09710 eaea0e58e20fb27b0c8d7fc7b2f7b786 267 Pfam PF13460 NAD(P)H-binding 11 193 1.4E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09710 eaea0e58e20fb27b0c8d7fc7b2f7b786 267 SUPERFAMILY SSF51735 3 244 6.73E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS06590 15ac9ff6fd11517ad0b1a11ca54f9ed7 295 PANTHER PTHR23054:SF21 128 273 8.1E-20 T 22-04-2016 MED134_RS06590 15ac9ff6fd11517ad0b1a11ca54f9ed7 295 Pfam PF04784 Protein of unknown function, DUF547 130 234 1.3E-26 T 22-04-2016 IPR006869 Domain of unknown function DUF547 MED134_RS06590 15ac9ff6fd11517ad0b1a11ca54f9ed7 295 PANTHER PTHR23054 128 273 8.1E-20 T 22-04-2016 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 171 3.6E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Gene3D G3DSA:3.40.50.670 376 544 4.4E-60 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Pfam PF01751 Toprim domain 409 514 1.1E-13 T 22-04-2016 IPR006171 Toprim domain MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PANTHER PTHR10169:SF28 5 618 5.7E-279 T 22-04-2016 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 SUPERFAMILY SSF56719 396 607 4.45E-58 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 SMART SM00387 37 172 1.4E-6 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PANTHER PTHR10169 5 618 5.7E-279 T 22-04-2016 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 ProSitePatterns PS00177 DNA topoisomerase II signature. 412 420 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Gene3D G3DSA:3.30.230.10 209 375 3.2E-43 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 546 604 1.1E-6 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Pfam PF00204 DNA gyrase B 213 368 4.8E-27 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 550 566 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 410 424 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 490 507 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 41 56 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 75 88 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 510 522 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 110 124 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 254 267 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR00418 DNA topoisomerase II family signature 472 488 9.1E-49 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 Gene3D G3DSA:3.30.565.10 7 206 2.2E-54 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR01159 DNA gyrase subunit B signature 585 601 1.8E-5 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR01159 DNA gyrase subunit B signature 344 358 1.8E-5 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR01159 DNA gyrase subunit B signature 358 378 1.8E-5 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 PRINTS PR01159 DNA gyrase subunit B signature 192 205 1.8E-5 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 SUPERFAMILY SSF54211 210 367 1.63E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 SUPERFAMILY SSF55874 6 205 5.67E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS02600 2e393459a4b59b93c459e26c7bd16174 618 SMART SM00433 41 609 1.3E-156 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 PANTHER PTHR34599 96 442 1.2E-32 T 22-04-2016 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 PANTHER PTHR34599 43 80 1.2E-32 T 22-04-2016 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 SUPERFAMILY SSF48317 159 439 1.18E-42 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 Gene3D G3DSA:1.10.606.10 238 446 2.5E-93 T 22-04-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 Gene3D G3DSA:1.10.606.10 73 203 2.5E-93 T 22-04-2016 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 Pfam PF01569 PAP2 superfamily 319 429 4.0E-13 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 PANTHER PTHR34599:SF1 96 442 1.2E-32 T 22-04-2016 MED134_RS10630 b10b9d97b13c5a888ebbec5da6e107dc 451 PANTHER PTHR34599:SF1 43 80 1.2E-32 T 22-04-2016 MED134_RS06605 b79dca2d16057a08fb4d0b3507357f52 108 Pfam PF01638 HxlR-like helix-turn-helix 19 104 1.8E-31 T 22-04-2016 IPR002577 Helix-turn-helix, HxlR type MED134_RS06605 b79dca2d16057a08fb4d0b3507357f52 108 PANTHER PTHR33204:SF5 8 107 1.2E-38 T 22-04-2016 MED134_RS06605 b79dca2d16057a08fb4d0b3507357f52 108 SUPERFAMILY SSF46785 7 104 2.87E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS06605 b79dca2d16057a08fb4d0b3507357f52 108 PANTHER PTHR33204 8 107 1.2E-38 T 22-04-2016 MED134_RS06605 b79dca2d16057a08fb4d0b3507357f52 108 Gene3D G3DSA:1.10.10.10 4 104 3.9E-37 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 PANTHER PTHR23083 62 155 6.7E-13 T 22-04-2016 MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 Pfam PF13414 TPR repeat 122 155 4.3E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 SMART SM00028 115 148 1.1E-7 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 SMART SM00028 78 111 48.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 Gene3D G3DSA:1.25.40.10 60 165 2.3E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09935 27e47e70be5ba86d8bb43c010460e972 296 SUPERFAMILY SSF48452 60 163 1.34E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 SUPERFAMILY SSF88946 10 78 8.24E-15 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 Gene3D G3DSA:1.10.10.10 119 180 2.0E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 Gene3D G3DSA:1.10.1740.10 10 95 2.7E-17 T 22-04-2016 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 Pfam PF08281 Sigma-70, region 4 122 174 9.0E-9 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 Pfam PF04542 Sigma-70 region 2 12 77 4.7E-11 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 PANTHER PTHR30173 11 182 1.2E-27 T 22-04-2016 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 SUPERFAMILY SSF88659 92 180 6.73E-12 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS11980 28d1d4757dc41c98e4854c69880803f3 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 176 9.7E-24 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 PANTHER PTHR10366:SF41 2 346 5.2E-163 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 SUPERFAMILY SSF51735 1 345 1.66E-93 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 317 4.9E-104 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 PANTHER PTHR10366 2 346 5.2E-163 T 22-04-2016 MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 Gene3D G3DSA:3.90.25.10 188 344 4.2E-53 T 22-04-2016 MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 333 1.3E-140 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 MED134_RS01340 f160e90d71e123cf49b9304d78ec659d 347 Gene3D G3DSA:3.40.50.720 1 187 5.0E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00775 fecc6a9dff1f0c5c13b1360d3f4afd9d 763 Pfam PF07715 TonB-dependent Receptor Plug Domain 143 221 6.9E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00775 fecc6a9dff1f0c5c13b1360d3f4afd9d 763 Gene3D G3DSA:2.170.130.10 144 225 4.0E-13 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS00775 fecc6a9dff1f0c5c13b1360d3f4afd9d 763 SUPERFAMILY SSF56935 125 763 2.24E-58 T 22-04-2016 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 11 374 9.8E-144 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 SUPERFAMILY SSF51713 1 372 1.31E-147 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 366 51.574 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 PANTHER PTHR21148:SF26 1 372 1.1E-145 T 22-04-2016 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 367 1.1E-82 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 11 374 1.4E-148 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 Gene3D G3DSA:3.20.20.105 1 372 2.0E-152 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 MED134_RS05775 b56496f64d05c641b0710b745a7010b7 376 PANTHER PTHR21148 1 372 1.1E-145 T 22-04-2016 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 PANTHER PTHR15362:SF2 103 149 1.5E-20 T 22-04-2016 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 PANTHER PTHR15362:SF2 1 87 1.5E-20 T 22-04-2016 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 Pfam PF01066 CDP-alcohol phosphatidyltransferase 7 70 3.9E-13 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 PANTHER PTHR15362 103 149 1.5E-20 T 22-04-2016 MED134_RS13555 d2977acc832d03fbe8f1f8eac10b8b68 240 PANTHER PTHR15362 1 87 1.5E-20 T 22-04-2016 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 346 65.909 T 22-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 Gene3D G3DSA:3.20.20.70 107 318 9.1E-18 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 PANTHER PTHR30544:SF5 1 346 1.2E-144 T 22-04-2016 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 PIRSF PIRSF006004 3 346 2.3E-122 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 Pfam PF13394 4Fe-4S single cluster domain 113 218 2.3E-8 T 22-04-2016 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 PANTHER PTHR30544 1 346 1.2E-144 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 345 1.1E-118 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 Pfam PF04055 Radical SAM superfamily 109 275 3.0E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 SMART SM00729 104 320 0.0091 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS05530 51cd9074c9632c56ca167669e6673395 346 SUPERFAMILY SSF102114 103 318 1.01E-15 T 22-04-2016 MED134_RS10990 5001edf181aa6538d88d74f745947d32 222 SUPERFAMILY SSF81343 3 221 2.22E-44 T 22-04-2016 MED134_RS10990 5001edf181aa6538d88d74f745947d32 222 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 83 202 1.4E-6 T 22-04-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 MED134_RS10990 5001edf181aa6538d88d74f745947d32 222 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 7 217 2.6E-49 T 22-04-2016 IPR011138 Succinate dehydrogenase cytochrome b558 subunit UniPathway: UPA00223 MED134_RS10990 5001edf181aa6538d88d74f745947d32 222 Gene3D G3DSA:1.20.950.10 14 214 9.8E-16 T 22-04-2016 MED134_RS02145 395b927d377d6050c481fba2efecaa93 130 SUPERFAMILY SSF52833 22 129 1.66E-9 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS02145 395b927d377d6050c481fba2efecaa93 130 Pfam PF11009 Protein of unknown function (DUF2847) 24 126 6.6E-39 T 22-04-2016 IPR022551 Protein of unknown function DUF2847 MED134_RS02145 395b927d377d6050c481fba2efecaa93 130 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 24 127 7.2E-42 T 22-04-2016 IPR022551 Protein of unknown function DUF2847 MED134_RS02145 395b927d377d6050c481fba2efecaa93 130 Gene3D G3DSA:3.40.30.10 25 130 6.0E-7 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS05495 10d355f76ba113e15acfa2b88a1d5b3b 234 Pfam PF13568 Outer membrane protein beta-barrel domain 28 200 7.1E-22 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS14275 bf6da90ae986da3ad263fb181a33989e 419 PANTHER PTHR13693 43 401 8.1E-98 T 22-04-2016 MED134_RS14275 bf6da90ae986da3ad263fb181a33989e 419 Gene3D G3DSA:3.40.640.10 68 284 7.0E-67 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS14275 bf6da90ae986da3ad263fb181a33989e 419 SUPERFAMILY SSF53383 39 401 1.65E-81 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS14275 bf6da90ae986da3ad263fb181a33989e 419 Pfam PF00155 Aminotransferase class I and II 45 393 4.2E-42 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS14275 bf6da90ae986da3ad263fb181a33989e 419 Gene3D G3DSA:3.90.1150.10 285 399 3.4E-14 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 192 1.4E-64 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 Gene3D G3DSA:3.40.50.300 3 195 9.9E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 Pfam PF01926 50S ribosome-binding GTPase 26 143 5.4E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 196 25.858 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 PANTHER PTHR11649 1 195 1.2E-53 T 22-04-2016 MED134_RS12480 0b0eac92fcd3ce8e44a42893139cc58c 201 SUPERFAMILY SSF52540 16 194 2.55E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 114 1.5E-20 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 Gene3D G3DSA:3.40.50.720 2 142 7.7E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 SUPERFAMILY SSF51735 2 171 1.14E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 SUPERFAMILY SSF55347 126 289 1.32E-32 T 22-04-2016 MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 Gene3D G3DSA:3.30.360.10 143 322 1.8E-44 T 22-04-2016 MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 PANTHER PTHR22604:SF105 1 322 4.0E-90 T 22-04-2016 MED134_RS00205 b26e145a7703767d5b9199f9e2a8fba3 322 PANTHER PTHR22604 1 322 4.0E-90 T 22-04-2016 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 SUPERFAMILY SSF69864 173 391 4.71E-56 T 22-04-2016 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 PANTHER PTHR11587:SF2 1 393 7.4E-115 T 22-04-2016 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 Pfam PF00764 Arginosuccinate synthase 5 387 3.4E-89 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 Gene3D G3DSA:3.40.50.620 2 171 1.8E-40 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 7 15 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 Gene3D G3DSA:3.90.1260.10 173 393 6.4E-55 T 22-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 PANTHER PTHR11587 1 393 7.4E-115 T 22-04-2016 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 TIGRFAM TIGR00032 argG: argininosuccinate synthase 3 389 1.5E-84 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 MED134_RS11740 b0c13e8212d590bb4a30e2388f10a3ba 393 SUPERFAMILY SSF52402 1 185 2.07E-38 T 22-04-2016 MED134_RS01910 84fc06805681180548db2e572ceac416 227 SUPERFAMILY SSF52317 1 225 9.3E-78 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS01910 84fc06805681180548db2e572ceac416 227 PANTHER PTHR11019 1 64 5.3E-65 T 22-04-2016 MED134_RS01910 84fc06805681180548db2e572ceac416 227 PANTHER PTHR11019 85 224 5.3E-65 T 22-04-2016 MED134_RS01910 84fc06805681180548db2e572ceac416 227 Pfam PF01965 DJ-1/PfpI family 27 223 1.6E-16 T 22-04-2016 IPR002818 DJ-1/PfpI MED134_RS01910 84fc06805681180548db2e572ceac416 227 PANTHER PTHR11019:SF97 1 64 5.3E-65 T 22-04-2016 MED134_RS01910 84fc06805681180548db2e572ceac416 227 PANTHER PTHR11019:SF97 85 224 5.3E-65 T 22-04-2016 MED134_RS01910 84fc06805681180548db2e572ceac416 227 Gene3D G3DSA:3.40.50.880 1 226 1.7E-92 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12075 0393bfdca9948b7f72f262638bb32215 229 PANTHER PTHR24023 1 226 1.1E-44 T 22-04-2016 MED134_RS12075 0393bfdca9948b7f72f262638bb32215 229 Pfam PF01391 Collagen triple helix repeat (20 copies) 4 60 1.2E-8 T 22-04-2016 IPR008160 Collagen triple helix repeat MED134_RS12075 0393bfdca9948b7f72f262638bb32215 229 Pfam PF01391 Collagen triple helix repeat (20 copies) 169 226 2.6E-8 T 22-04-2016 IPR008160 Collagen triple helix repeat MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 Pfam PF00491 Arginase family 21 278 4.6E-65 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 TIGRFAM TIGR01230 agmatinase: agmatinase 16 279 1.2E-69 T 22-04-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 SUPERFAMILY SSF52768 15 282 1.6E-72 T 22-04-2016 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 PANTHER PTHR11358 4 303 1.7E-89 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 PIRSF PIRSF036979 2 284 1.7E-57 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 Gene3D G3DSA:3.40.800.10 14 280 3.2E-68 T 22-04-2016 IPR023696 Ureohydrolase domain MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 ProSitePatterns PS01053 Arginase family signature. 209 230 - T 22-04-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 MED134_RS01475 b373fdc7c0c60eb59b7e88a7ee290b0d 312 PANTHER PTHR11358:SF34 4 303 1.7E-89 T 22-04-2016 MED134_RS03275 dd2ecc003bb04277257aad4c5364ebe0 192 SUPERFAMILY SSF81901 51 148 2.88E-6 T 22-04-2016 MED134_RS03275 dd2ecc003bb04277257aad4c5364ebe0 192 Gene3D G3DSA:1.25.40.10 51 155 2.3E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05300 48866f7fcfae4a4bbf0915e5fe2dc9e5 113 Pfam PF03551 Transcriptional regulator PadR-like family 19 89 6.5E-18 T 22-04-2016 IPR005149 Transcription regulator PadR, N-terminal MED134_RS05300 48866f7fcfae4a4bbf0915e5fe2dc9e5 113 SUPERFAMILY SSF46785 9 101 1.86E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05300 48866f7fcfae4a4bbf0915e5fe2dc9e5 113 Gene3D G3DSA:1.10.10.10 4 106 4.2E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05300 48866f7fcfae4a4bbf0915e5fe2dc9e5 113 PANTHER PTHR33169 1 103 3.7E-29 T 22-04-2016 MED134_RS05300 48866f7fcfae4a4bbf0915e5fe2dc9e5 113 PANTHER PTHR33169:SF3 1 103 3.7E-29 T 22-04-2016 MED134_RS02640 53269585c612fe0c73936a10a0b4acac 235 Pfam PF13847 Methyltransferase domain 57 148 7.0E-16 T 22-04-2016 IPR025714 Methyltransferase domain MED134_RS02640 53269585c612fe0c73936a10a0b4acac 235 Gene3D G3DSA:3.40.50.150 33 231 2.8E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS02640 53269585c612fe0c73936a10a0b4acac 235 SUPERFAMILY SSF53335 45 177 1.98E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS02095 f2a366318238bc9c5c4ffa5335935ff8 264 Gene3D G3DSA:2.60.40.1190 48 264 4.1E-50 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS02095 f2a366318238bc9c5c4ffa5335935ff8 264 ProDom PD004647 DEGRADATION HYDROLASE GLYCOSIDASE XYLAN A XYLANASE PRECURSOR SIGNAL REPEAT 14- 56 264 9.0E-6 T 22-04-2016 MED134_RS02095 f2a366318238bc9c5c4ffa5335935ff8 264 SUPERFAMILY SSF49344 49 263 2.2E-35 T 22-04-2016 MED134_RS02095 f2a366318238bc9c5c4ffa5335935ff8 264 Pfam PF06452 Carbohydrate family 9 binding domain-like 58 263 5.0E-48 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 SUPERFAMILY SSF103473 4 403 1.06E-52 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 Gene3D G3DSA:1.20.1250.20 13 188 1.1E-23 T 22-04-2016 MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 Gene3D G3DSA:1.20.1250.20 213 399 1.5E-5 T 22-04-2016 MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 PANTHER PTHR23502:SF19 8 388 9.8E-94 T 22-04-2016 MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 PANTHER PTHR23502 8 388 9.8E-94 T 22-04-2016 MED134_RS01635 b4c5024f5f92c41f5603cb948ee8fe5b 406 Pfam PF07690 Major Facilitator Superfamily 19 355 2.7E-34 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 PANTHER PTHR10314 11 369 1.0E-160 T 22-04-2016 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 Gene3D G3DSA:3.40.50.1100 103 346 8.1E-83 T 22-04-2016 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 SUPERFAMILY SSF53686 7 364 7.33E-98 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 PANTHER PTHR10314:SF30 11 369 1.0E-160 T 22-04-2016 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 TIGRFAM TIGR02079 THD1: threonine dehydratase 14 421 1.2E-188 T 22-04-2016 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 328 414 2.2E-20 T 22-04-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 MED134_RS04720 9668039bc9465484be12c43a1ad4c374 421 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 315 2.4E-77 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MED134_RS06105 84e18056de97879c94bcaba913184993 388 Gene3D G3DSA:3.40.800.10 75 302 4.6E-22 T 22-04-2016 IPR023696 Ureohydrolase domain MED134_RS06105 84e18056de97879c94bcaba913184993 388 SUPERFAMILY SSF52768 29 304 5.22E-48 T 22-04-2016 MED134_RS06105 84e18056de97879c94bcaba913184993 388 Pfam PF00491 Arginase family 80 298 1.7E-9 T 22-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 Gene3D G3DSA:3.30.450.20 136 275 2.5E-30 T 22-04-2016 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SUPERFAMILY SSF55874 353 506 9.69E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SMART SM00091 151 219 0.56 T 22-04-2016 IPR000014 PAS domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SMART SM00091 19 92 20.0 T 22-04-2016 IPR000014 PAS domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 1.6E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 1.6E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 1.6E-5 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SUPERFAMILY SSF55785 41 140 1.9E-10 T 22-04-2016 IPR000014 PAS domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SMART SM00387 398 510 6.3E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 Gene3D G3DSA:3.30.565.10 364 506 2.3E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 198 274 2.9E-7 T 22-04-2016 IPR000014 PAS domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SMART SM00086 226 269 1.1E-5 T 22-04-2016 IPR001610 PAC motif MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SMART SM00086 98 139 0.0058 T 22-04-2016 IPR001610 PAC motif MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 506 3.6E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 Gene3D G3DSA:3.30.450.20 23 135 5.2E-12 T 22-04-2016 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 PANTHER PTHR24423 68 506 6.2E-51 T 22-04-2016 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 Pfam PF08447 PAS fold 174 263 9.4E-17 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 MED134_RS04775 70e526f4e75ace18818e6e7873281d3d 511 SUPERFAMILY SSF55785 159 270 1.48E-17 T 22-04-2016 IPR000014 PAS domain MED134_RS11030 8c2d3e7316487c386354b14950100409 420 SUPERFAMILY SSF51126 73 353 1.02E-6 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor MED134_RS11030 8c2d3e7316487c386354b14950100409 420 PANTHER PTHR41339 51 419 7.7E-27 T 22-04-2016 MED134_RS04855 cb2837aa3f431c34245533139be0f0f6 181 SUPERFAMILY SSF52172 5 167 1.27E-17 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS04855 cb2837aa3f431c34245533139be0f0f6 181 Pfam PF00072 Response regulator receiver domain 7 114 1.2E-12 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04855 cb2837aa3f431c34245533139be0f0f6 181 SMART SM00448 5 118 3.0E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS04855 cb2837aa3f431c34245533139be0f0f6 181 PANTHER PTHR26402 5 108 1.8E-14 T 22-04-2016 MED134_RS04855 cb2837aa3f431c34245533139be0f0f6 181 Gene3D G3DSA:3.40.50.2300 4 114 1.5E-17 T 22-04-2016 MED134_RS13080 9a05414dc2e3ef37b4271266d0173a91 101 Pfam PF00581 Rhodanese-like domain 8 99 3.0E-15 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13080 9a05414dc2e3ef37b4271266d0173a91 101 Gene3D G3DSA:3.40.250.10 2 100 5.9E-27 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13080 9a05414dc2e3ef37b4271266d0173a91 101 SUPERFAMILY SSF52821 3 100 4.45E-27 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS13080 9a05414dc2e3ef37b4271266d0173a91 101 SMART SM00450 5 101 9.6E-17 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12470 f87194e1b35a409124eb65a8ad979255 112 TIGRFAM TIGR03515 GldC: gliding motility-associated protein GldC 6 109 6.4E-44 T 22-04-2016 IPR019854 Gliding motility-associated protein, GldC MED134_RS02700 a417a54fd1daf294f82b16a6bc78ad3b 283 PANTHER PTHR30024 3 275 1.6E-49 T 22-04-2016 MED134_RS02700 a417a54fd1daf294f82b16a6bc78ad3b 283 Pfam PF09084 NMT1/THI5 like 18 166 2.9E-8 T 22-04-2016 IPR015168 SsuA/THI5-like MED134_RS02700 a417a54fd1daf294f82b16a6bc78ad3b 283 PANTHER PTHR30024:SF1 3 275 1.6E-49 T 22-04-2016 MED134_RS02700 a417a54fd1daf294f82b16a6bc78ad3b 283 Gene3D G3DSA:3.40.190.10 91 205 2.3E-5 T 22-04-2016 MED134_RS02700 a417a54fd1daf294f82b16a6bc78ad3b 283 SUPERFAMILY SSF53850 3 221 4.14E-28 T 22-04-2016 MED134_RS12395 76222762d8d7337b4bed5dca7201ec0d 304 Gene3D G3DSA:3.75.10.10 3 304 8.9E-57 T 22-04-2016 MED134_RS12395 76222762d8d7337b4bed5dca7201ec0d 304 Pfam PF02274 Amidinotransferase 51 303 3.9E-18 T 22-04-2016 MED134_RS12395 76222762d8d7337b4bed5dca7201ec0d 304 SUPERFAMILY SSF55909 3 304 4.1E-44 T 22-04-2016 MED134_RS12395 76222762d8d7337b4bed5dca7201ec0d 304 PANTHER PTHR12737 56 304 2.1E-16 T 22-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 MED134_RS07815 7dd000173882a5c64d6c15613381083e 123 SUPERFAMILY SSF54593 7 122 1.31E-18 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS07815 7dd000173882a5c64d6c15613381083e 123 Gene3D G3DSA:3.10.180.10 6 122 9.2E-19 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS08100 b5e0e71292fcaa5db2bd6207ce3329ac 170 Pfam PF07274 Protein of unknown function (DUF1440) 33 158 4.9E-26 T 22-04-2016 IPR009898 Protein of unknown function DUF1440 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 Gene3D G3DSA:3.20.20.80 249 471 1.2E-73 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 Gene3D G3DSA:3.20.20.80 38 211 1.2E-73 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 PANTHER PTHR10357:SF11 34 171 1.8E-57 T 22-04-2016 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 PANTHER PTHR10357:SF11 207 501 1.8E-57 T 22-04-2016 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 PANTHER PTHR10357 34 171 1.8E-57 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 PANTHER PTHR10357 207 501 1.8E-57 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 Pfam PF00128 Alpha amylase, catalytic domain 78 422 4.3E-38 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 SMART SM00642 46 465 8.1E-54 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 SUPERFAMILY SSF51445 34 211 1.75E-69 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS13970 d783f13c4bed11d642ec49392a1cf6bb 557 SUPERFAMILY SSF51445 249 471 1.75E-69 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 PRINTS PR00147 DNA photolyase signature 390 404 3.07E-6 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 PRINTS PR00147 DNA photolyase signature 351 369 3.07E-6 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 PRINTS PR00147 DNA photolyase signature 331 347 3.07E-6 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 PANTHER PTHR11455 1 429 3.7E-167 T 22-04-2016 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 Gene3D G3DSA:3.40.50.620 2 147 3.9E-39 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 Gene3D G3DSA:1.25.40.80 148 291 9.5E-55 T 22-04-2016 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 SUPERFAMILY SSF52425 3 193 7.06E-44 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 SUPERFAMILY SSF48173 207 428 1.44E-68 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 Pfam PF00875 DNA photolyase 4 164 2.7E-37 T 22-04-2016 IPR006050 DNA photolyase, N-terminal MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 Gene3D G3DSA:1.10.579.10 292 429 5.0E-47 T 22-04-2016 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 TIGRFAM TIGR02765 crypto_DASH: cryptochrome, DASH family 3 429 1.0E-144 T 22-04-2016 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 Pfam PF03441 FAD binding domain of DNA photolyase 284 429 1.1E-33 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain MED134_RS10055 b3b2b63262f873fba7af03a32f2532a1 432 PANTHER PTHR11455:SF22 1 429 3.7E-167 T 22-04-2016 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 MED134_RS08210 1feefba72e645c7347d5328d92d16391 160 SUPERFAMILY SSF55729 1 156 6.85E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08210 1feefba72e645c7347d5328d92d16391 160 Gene3D G3DSA:3.40.630.30 1 157 5.9E-35 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08210 1feefba72e645c7347d5328d92d16391 160 PANTHER PTHR23091 1 156 4.4E-15 T 22-04-2016 MED134_RS08210 1feefba72e645c7347d5328d92d16391 160 Pfam PF00583 Acetyltransferase (GNAT) family 54 132 8.3E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS14550 99ea6bc815461712a9f91da8900bd7ee 389 Gene3D G3DSA:3.20.20.220 68 387 4.3E-96 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like MED134_RS14550 99ea6bc815461712a9f91da8900bd7ee 389 PANTHER PTHR13914:SF0 6 387 1.2E-120 T 22-04-2016 MED134_RS14550 99ea6bc815461712a9f91da8900bd7ee 389 PANTHER PTHR13914 6 387 1.2E-120 T 22-04-2016 IPR015659 Proline oxidase family GO:0004657|GO:0006562 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 MED134_RS14550 99ea6bc815461712a9f91da8900bd7ee 389 Pfam PF01619 Proline dehydrogenase 77 375 3.3E-84 T 22-04-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 MED134_RS14550 99ea6bc815461712a9f91da8900bd7ee 389 SUPERFAMILY SSF51730 69 387 2.12E-91 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like MED134_RS00055 27fa8a436ba9a70ad668fbfafe5553a1 416 Pfam PF05684 Protein of unknown function (DUF819) 18 411 6.1E-91 T 22-04-2016 IPR008537 Protein of unknown function DUF819 MED134_RS00055 27fa8a436ba9a70ad668fbfafe5553a1 416 PANTHER PTHR34289:SF3 24 412 2.6E-79 T 22-04-2016 MED134_RS00055 27fa8a436ba9a70ad668fbfafe5553a1 416 PANTHER PTHR34289 24 412 2.6E-79 T 22-04-2016 MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 PANTHER PTHR32315 3 159 4.6E-77 T 22-04-2016 MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 162 2.5E-63 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 SUPERFAMILY SSF53271 5 165 2.56E-47 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 Pfam PF00156 Phosphoribosyl transferase domain 34 147 1.9E-12 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 Gene3D G3DSA:3.40.50.2020 2 164 1.9E-62 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS00770 08241281bbb80c799e090a26d9598d0e 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 34.365 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 485 531 0.0081 T 22-04-2016 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 Gene3D G3DSA:1.50.10.10 202 326 1.8E-20 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 Gene3D G3DSA:1.50.10.10 362 537 1.8E-20 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 SUPERFAMILY SSF48208 171 546 2.48E-71 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 Gene3D G3DSA:3.40.30.10 24 141 2.8E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 Pfam PF03190 Protein of unknown function, DUF255 6 158 3.5E-65 T 22-04-2016 IPR004879 Domain of unknown function DUF255 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 SUPERFAMILY SSF52833 5 143 4.84E-32 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 PANTHER PTHR12145:SF11 6 678 5.2E-235 T 22-04-2016 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 PANTHER PTHR12145 6 678 5.2E-235 T 22-04-2016 MED134_RS11420 17aab7f4bc7e41f9b62227c58f8dd559 679 PIRSF PIRSF006402 1 679 4.4E-222 T 22-04-2016 IPR024705 Spermatogenesis-associated protein 20 MED134_RS14160 65118effa497854320b07d1d93b2ea6d 300 Pfam PF04230 Polysaccharide pyruvyl transferase 206 249 9.9E-6 T 22-04-2016 IPR007345 Polysaccharide pyruvyl transferase MED134_RS13625 22c7b9f09fb0070135fdef7c26de5dcd 378 Pfam PF13524 Glycosyl transferases group 1 292 373 1.2E-8 T 22-04-2016 MED134_RS13625 22c7b9f09fb0070135fdef7c26de5dcd 378 SUPERFAMILY SSF53756 15 375 3.18E-19 T 22-04-2016 MED134_RS01165 42d54d74307eed6677f44375888c2c3a 972 SUPERFAMILY SSF56059 889 945 6.0E-26 T 22-04-2016 MED134_RS01165 42d54d74307eed6677f44375888c2c3a 972 SUPERFAMILY SSF56059 621 857 6.0E-26 T 22-04-2016 MED134_RS01165 42d54d74307eed6677f44375888c2c3a 972 Gene3D G3DSA:3.30.1490.20 607 810 5.7E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MED134_RS01165 42d54d74307eed6677f44375888c2c3a 972 Gene3D G3DSA:3.30.470.20 811 947 2.4E-7 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS01165 42d54d74307eed6677f44375888c2c3a 972 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 623 950 1.9E-25 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MED134_RS08505 f8b3ece7e71ad49eac5b0d71933988c2 485 Pfam PF08811 Protein of unknown function (DUF1800) 30 484 6.7E-89 T 22-04-2016 IPR014917 Protein of unknown function DUF1800 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 SUPERFAMILY SSF64005 9 235 4.58E-88 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 4.8E-92 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 Gene3D G3DSA:3.40.1180.10 6 245 2.4E-102 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 22-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 40.183 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 1.0E-83 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS07525 86a4cfbf8365af29a4aac407d89acec7 246 PANTHER PTHR10291 3 245 3.1E-119 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 MED134_RS08960 a17d59e4c6b6ebd4118e4c45194b9669 197 PANTHER PTHR10520 1 196 1.8E-60 T 22-04-2016 MED134_RS08960 a17d59e4c6b6ebd4118e4c45194b9669 197 PANTHER PTHR10520:SF9 1 196 1.8E-60 T 22-04-2016 MED134_RS08960 a17d59e4c6b6ebd4118e4c45194b9669 197 SUPERFAMILY SSF53328 2 196 4.45E-44 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS08960 a17d59e4c6b6ebd4118e4c45194b9669 197 Gene3D G3DSA:3.40.50.170 1 196 4.2E-51 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS08960 a17d59e4c6b6ebd4118e4c45194b9669 197 Pfam PF00551 Formyl transferase 2 192 2.6E-40 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MED134_RS14420 f976e4d464880b8250ddc87517ea0780 203 SUPERFAMILY SSF55961 10 197 5.15E-22 T 22-04-2016 MED134_RS14420 f976e4d464880b8250ddc87517ea0780 203 Gene3D G3DSA:3.30.530.20 19 197 2.9E-15 T 22-04-2016 IPR023393 START-like domain MED134_RS11005 5b422a5235852126782e6c0266d2bcf0 328 PANTHER PTHR23409 5 328 1.0E-213 T 22-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 MED134_RS11005 5b422a5235852126782e6c0266d2bcf0 328 Gene3D G3DSA:1.10.620.20 5 289 8.0E-115 T 22-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 MED134_RS11005 5b422a5235852126782e6c0266d2bcf0 328 SUPERFAMILY SSF47240 5 306 6.2E-111 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS11005 5b422a5235852126782e6c0266d2bcf0 328 Pfam PF00268 Ribonucleotide reductase, small chain 14 281 2.0E-114 T 22-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 MED134_RS11005 5b422a5235852126782e6c0266d2bcf0 328 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 104 120 - T 22-04-2016 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 MED134_RS12940 e8cf392b6040b776cd472ba51826d45b 281 PANTHER PTHR11624 3 272 1.9E-83 T 22-04-2016 IPR033247 Transketolase family MED134_RS12940 e8cf392b6040b776cd472ba51826d45b 281 Gene3D G3DSA:3.40.50.970 3 273 6.1E-92 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS12940 e8cf392b6040b776cd472ba51826d45b 281 SUPERFAMILY SSF52518 3 274 5.24E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS12940 e8cf392b6040b776cd472ba51826d45b 281 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 269 9.0E-53 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 MED134_RS07065 933868a1da10c66300a3ab504199ce73 238 PANTHER PTHR17985 2 121 2.1E-13 T 22-04-2016 IPR008551 Transport and Golgi organisation protein 2 MED134_RS07065 933868a1da10c66300a3ab504199ce73 238 Pfam PF05742 Transport and Golgi organisation 2 1 174 3.9E-15 T 22-04-2016 IPR008551 Transport and Golgi organisation protein 2 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 SUPERFAMILY SSF52172 1 183 1.37E-38 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 PANTHER PTHR26402:SF292 4 223 6.2E-71 T 22-04-2016 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 Pfam PF00072 Response regulator receiver domain 7 115 2.7E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 PANTHER PTHR26402 4 223 6.2E-71 T 22-04-2016 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 Gene3D G3DSA:1.10.10.10 126 223 5.3E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 SMART SM00448 4 115 4.2E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 SMART SM00862 149 223 2.8E-15 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 223 1.2E-18 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS07150 2d59f0bb77626f1ca104ff0d71876ec4 225 Gene3D G3DSA:3.40.50.2300 2 125 1.2E-37 T 22-04-2016 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 SUPERFAMILY SSF63737 37 226 9.94E-19 T 22-04-2016 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 Pfam PF01433 Peptidase family M1 41 374 1.8E-26 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 Gene3D G3DSA:1.10.390.10 340 476 1.6E-14 T 22-04-2016 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 PANTHER PTHR11533:SF185 39 478 6.4E-36 T 22-04-2016 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 PANTHER PTHR11533 39 478 6.4E-36 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS03200 be6a524909ee33d82db8ac62e6a87def 539 SUPERFAMILY SSF55486 240 473 6.23E-37 T 22-04-2016 MED134_RS11880 a947329032a8f7edee537beb10da8b8e 1269 SUPERFAMILY SSF52129 523 903 1.15E-69 T 22-04-2016 IPR029030 Caspase-like domain MED134_RS11880 a947329032a8f7edee537beb10da8b8e 1269 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 1176 1260 1.7E-6 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS11880 a947329032a8f7edee537beb10da8b8e 1269 Pfam PF01364 Peptidase family C25 531 900 4.5E-83 T 22-04-2016 IPR001769 Gingipain GO:0006508|GO:0008234 MED134_RS11880 a947329032a8f7edee537beb10da8b8e 1269 Gene3D G3DSA:3.40.50.10390 527 669 5.4E-16 T 22-04-2016 IPR029031 Gingipain, N-terminal MED134_RS11880 a947329032a8f7edee537beb10da8b8e 1269 Gene3D G3DSA:3.40.50.1460 674 901 1.4E-56 T 22-04-2016 IPR029030 Caspase-like domain MED134_RS06840 5e7152eac3cb5bf48827f5767506d03e 181 PANTHER PTHR10851 25 98 1.1E-14 T 22-04-2016 MED134_RS06840 5e7152eac3cb5bf48827f5767506d03e 181 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 24 99 2.1E-14 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 MED134_RS06840 5e7152eac3cb5bf48827f5767506d03e 181 SUPERFAMILY SSF50475 10 181 3.37E-32 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS06840 5e7152eac3cb5bf48827f5767506d03e 181 Gene3D G3DSA:2.30.110.10 2 181 2.6E-41 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS14340 675aad92fbf36cbf1c2ccc5758afbc27 370 Gene3D G3DSA:1.10.10.10 294 363 2.0E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 ProSitePatterns PS00905 GTP1/OBG family signature. 216 229 - T 22-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 Gene3D G3DSA:3.40.50.300 163 331 3.7E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PANTHER PTHR11702 3 331 1.0E-142 T 22-04-2016 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 Hamap MF_01454 GTPase Obg [obg]. 5 331 43.944 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PANTHER PTHR11702:SF3 3 331 1.0E-142 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PIRSF PIRSF002401 3 332 1.1E-124 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 SUPERFAMILY SSF82051 5 161 1.22E-50 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 Pfam PF01926 50S ribosome-binding GTPase 164 281 3.5E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 Gene3D G3DSA:2.70.210.12 5 159 2.6E-51 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 6 330 1.5E-128 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 Pfam PF01018 GTP1/OBG 6 161 8.5E-56 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 SUPERFAMILY SSF52540 155 330 1.05E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 165 185 2.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 214 229 2.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 231 249 2.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS12025 f05b092ab20fffe134e65491db2e847e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 186 204 2.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 183 1.4E-63 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 PANTHER PTHR11603 1 327 2.2E-143 T 22-04-2016 MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 PANTHER PTHR11603:SF156 1 327 2.2E-143 T 22-04-2016 MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 Gene3D G3DSA:1.10.8.300 213 328 1.2E-35 T 22-04-2016 MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 Gene3D G3DSA:3.40.50.300 30 199 7.8E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 PIRSF PIRSF002849 1 333 3.4E-125 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted MED134_RS13120 40423e1946b3d8082b0cb9811c432fdd 333 SUPERFAMILY SSF52540 21 304 2.44E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 Gene3D G3DSA:1.10.287.90 76 156 3.4E-16 T 22-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 PANTHER PTHR22888 310 349 1.4E-39 T 22-04-2016 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 PANTHER PTHR22888 31 268 1.4E-39 T 22-04-2016 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 SUPERFAMILY SSF81464 71 155 4.41E-14 T 22-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 Gene3D G3DSA:2.60.40.420 314 348 3.3E-33 T 22-04-2016 IPR008972 Cupredoxin MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 Gene3D G3DSA:2.60.40.420 167 272 3.3E-33 T 22-04-2016 IPR008972 Cupredoxin MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 PANTHER PTHR22888:SF2 310 349 1.4E-39 T 22-04-2016 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 PANTHER PTHR22888:SF2 31 268 1.4E-39 T 22-04-2016 MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 SUPERFAMILY SSF49503 314 349 2.35E-32 T 22-04-2016 IPR008972 Cupredoxin MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 SUPERFAMILY SSF49503 166 272 2.35E-32 T 22-04-2016 IPR008972 Cupredoxin MED134_RS11220 bef5788469d7f6a8d859ad006c94e3f9 360 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 88 151 9.1E-7 T 22-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 MED134_RS06090 c68ff0f46796851b8c316961008eadd9 516 TIGRFAM TIGR03517 GldM_gliding: gliding motility-associated protein GldM 1 510 1.7E-118 T 22-04-2016 IPR019859 Gliding motility-associated protein GldM MED134_RS06090 c68ff0f46796851b8c316961008eadd9 516 Pfam PF12080 GldM C-terminal domain 329 498 2.5E-47 T 22-04-2016 IPR022719 Gliding motility-associated protein GldM, C-terminal MED134_RS06090 c68ff0f46796851b8c316961008eadd9 516 Pfam PF12081 GldM N-terminal domain 31 216 1.2E-42 T 22-04-2016 IPR022720 Gliding motility-associated protein GldM, N-terminal MED134_RS03915 b1e555502225a7a2ffcf31525c092c09 441 PANTHER PTHR10566 7 373 5.2E-64 T 22-04-2016 MED134_RS03915 b1e555502225a7a2ffcf31525c092c09 441 Pfam PF03109 ABC1 family 111 222 5.0E-21 T 22-04-2016 IPR004147 UbiB domain MED134_RS03915 b1e555502225a7a2ffcf31525c092c09 441 Gene3D G3DSA:3.90.1200.10 246 331 1.5E-6 T 22-04-2016 MED134_RS03915 b1e555502225a7a2ffcf31525c092c09 441 SUPERFAMILY SSF56112 92 154 5.13E-22 T 22-04-2016 IPR011009 Protein kinase-like domain MED134_RS03915 b1e555502225a7a2ffcf31525c092c09 441 SUPERFAMILY SSF56112 185 371 5.13E-22 T 22-04-2016 IPR011009 Protein kinase-like domain MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 Gene3D G3DSA:1.10.3860.10 1 418 2.3E-135 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 48 68 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 342 361 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 205 224 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 369 389 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 307 333 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PRINTS PR00173 Glutamate-aspartate symporter signature 157 179 1.9E-52 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 PANTHER PTHR11958 1 433 1.7E-157 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 Pfam PF00375 Sodium:dicarboxylate symporter family 6 414 6.8E-129 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 310 333 - T 22-04-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS03545 82dd6ca88a1578c89b77075ab3e666f2 433 SUPERFAMILY SSF118215 6 414 1.31E-117 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 MED134_RS06600 5477600d1973de243ef619677e5874de 235 SUPERFAMILY SSF53448 2 214 4.57E-38 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS06600 5477600d1973de243ef619677e5874de 235 PANTHER PTHR10859:SF92 3 205 1.1E-27 T 22-04-2016 MED134_RS06600 5477600d1973de243ef619677e5874de 235 Pfam PF00535 Glycosyl transferase family 2 5 140 1.9E-19 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS06600 5477600d1973de243ef619677e5874de 235 PANTHER PTHR10859 3 205 1.1E-27 T 22-04-2016 MED134_RS06600 5477600d1973de243ef619677e5874de 235 TIGRFAM TIGR04283 glyco_like_mftF: transferase 2, rSAM/selenodomain-associated 4 230 1.1E-71 T 22-04-2016 IPR026461 Transferase 2, rSAM/selenodomain-associated MED134_RS06600 5477600d1973de243ef619677e5874de 235 Gene3D G3DSA:3.90.550.10 4 228 5.6E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 Pfam PF01807 CHC2 zinc finger 27 88 1.8E-8 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 Gene3D G3DSA:3.40.1360.10 183 281 1.3E-13 T 22-04-2016 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 SUPERFAMILY SSF57783 6 85 4.76E-17 T 22-04-2016 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 SMART SM00400 31 85 0.0059 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 Pfam PF13155 Toprim-like 189 274 9.2E-11 T 22-04-2016 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 SUPERFAMILY SSF56731 182 281 2.35E-6 T 22-04-2016 MED134_RS00470 02f9f119573fd49c4b26aac806944057 291 Gene3D G3DSA:3.90.580.10 6 86 5.2E-17 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MED134_RS09630 53ee5c50aae6d3f8be23d3c76092faf4 127 SUPERFAMILY SSF50249 42 127 1.31E-9 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS09630 53ee5c50aae6d3f8be23d3c76092faf4 127 Pfam PF11325 Domain of unknown function (DUF3127) 2 89 5.0E-34 T 22-04-2016 IPR021474 Protein of unknown function DUF3127 MED134_RS09630 53ee5c50aae6d3f8be23d3c76092faf4 127 Gene3D G3DSA:2.40.50.140 34 127 2.1E-6 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 SUPERFAMILY SSF53448 174 292 4.44E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 SUPERFAMILY SSF53448 2 123 4.44E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 Gene3D G3DSA:3.90.550.10 184 250 3.2E-21 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 Gene3D G3DSA:3.90.550.10 6 144 3.2E-21 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 PANTHER PTHR22916 176 320 1.1E-15 T 22-04-2016 MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 PANTHER PTHR22916 2 134 1.1E-15 T 22-04-2016 MED134_RS13450 d1fe2f1c125fa076152d8c6133347359 320 Pfam PF00535 Glycosyl transferase family 2 5 124 1.0E-11 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 319 1.2E-69 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 SUPERFAMILY SSF54713 229 319 1.28E-16 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 SUPERFAMILY SSF54713 148 227 9.16E-13 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Hamap MF_00050 Elongation factor Ts [tsf]. 1 321 51.627 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 SUPERFAMILY SSF46934 3 55 3.74E-17 T 22-04-2016 IPR009060 UBA-like GO:0005515 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 22-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 22-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 SUPERFAMILY SSF54713 58 145 4.45E-17 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Gene3D G3DSA:1.10.286.20 236 278 7.1E-9 T 22-04-2016 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Gene3D G3DSA:3.30.479.20 58 95 1.1E-22 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Gene3D G3DSA:3.30.479.20 286 319 1.1E-22 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Gene3D G3DSA:3.30.479.20 176 191 1.1E-22 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Pfam PF00889 Elongation factor TS 73 214 1.0E-34 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Pfam PF00889 Elongation factor TS 228 319 1.1E-18 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 PANTHER PTHR11741 1 207 1.4E-78 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 PANTHER PTHR11741 250 317 1.4E-78 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 MED134_RS06810 aa5e51975c015f70a17d3f44f06a9d51 321 Gene3D G3DSA:1.10.8.10 2 55 8.1E-26 T 22-04-2016 MED134_RS13380 6cddac76120eb59be4e6278a4f8eea89 286 Gene3D G3DSA:3.90.550.10 4 236 1.2E-63 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13380 6cddac76120eb59be4e6278a4f8eea89 286 PANTHER PTHR22916 1 209 4.8E-55 T 22-04-2016 MED134_RS13380 6cddac76120eb59be4e6278a4f8eea89 286 SUPERFAMILY SSF53448 4 226 1.29E-57 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13380 6cddac76120eb59be4e6278a4f8eea89 286 Pfam PF00535 Glycosyl transferase family 2 7 132 3.6E-34 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13380 6cddac76120eb59be4e6278a4f8eea89 286 PANTHER PTHR22916:SF34 1 209 4.8E-55 T 22-04-2016 MED134_RS01255 2b32e564ccaf1b8566a34f9d63687135 393 Pfam PF03602 Conserved hypothetical protein 95 95 163 2.1E-4 T 22-04-2016 MED134_RS01255 2b32e564ccaf1b8566a34f9d63687135 393 SUPERFAMILY SSF53335 74 181 2.82E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01255 2b32e564ccaf1b8566a34f9d63687135 393 Gene3D G3DSA:3.40.50.150 83 182 2.1E-13 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 PRINTS PR01438 Universal stress protein signature 113 135 1.8E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 PRINTS PR01438 Universal stress protein signature 1 14 1.8E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 PRINTS PR01438 Universal stress protein signature 95 107 1.8E-6 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 SUPERFAMILY SSF52402 1 145 8.37E-21 T 22-04-2016 MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 Gene3D G3DSA:3.40.50.620 1 137 2.5E-19 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 Pfam PF00582 Universal stress protein family 1 135 2.5E-14 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS09010 bdeb4073e3264ff4f84e7f199c5a2ee0 264 SUPERFAMILY SSF52402 157 261 6.87E-5 T 22-04-2016 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 SUPERFAMILY SSF53383 2 380 5.44E-95 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 Gene3D G3DSA:3.40.640.10 46 256 2.0E-54 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 PANTHER PTHR11751 15 381 3.5E-104 T 22-04-2016 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 PANTHER PTHR11751:SF305 15 381 3.5E-104 T 22-04-2016 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 Pfam PF00155 Aminotransferase class I and II 32 380 3.6E-52 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS05615 d5c139a588743b7ac9927fbddb5faad3 381 Gene3D G3DSA:3.90.1150.10 257 380 5.0E-32 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 SUPERFAMILY SSF50104 126 271 1.68E-55 T 22-04-2016 IPR008991 Translation protein SH3-like domain MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Gene3D G3DSA:2.40.50.140 1 114 1.7E-50 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 274 1.5E-116 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 8.3E-32 T 22-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 246 2.3E-51 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 PANTHER PTHR13691:SF5 1 274 2.0E-130 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 SUPERFAMILY SSF50249 3 122 6.17E-46 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 PANTHER PTHR13691 1 274 2.0E-130 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 PIRSF PIRSF002158 13 274 1.0E-90 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Gene3D G3DSA:2.30.30.30 119 195 5.7E-32 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 SMART SM01382 124 251 9.1E-84 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 44.223 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 SMART SM01383 42 118 5.6E-42 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12250 baa11a3a8342ffec023dfd6418ad8adb 274 Gene3D G3DSA:4.10.950.10 196 273 1.2E-30 T 22-04-2016 IPR014726 Ribosomal protein L2, domain 3 MED134_RS00890 fa57b6dea1bf7cf87f3dbb4e050088cc 203 Gene3D G3DSA:3.40.30.10 21 202 9.6E-33 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS00890 fa57b6dea1bf7cf87f3dbb4e050088cc 203 SUPERFAMILY SSF52833 68 188 2.93E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS00890 fa57b6dea1bf7cf87f3dbb4e050088cc 203 PANTHER PTHR10681 73 190 9.9E-15 T 22-04-2016 MED134_RS00890 fa57b6dea1bf7cf87f3dbb4e050088cc 203 Pfam PF08534 Redoxin 68 188 7.7E-13 T 22-04-2016 IPR013740 Redoxin GO:0016491 MED134_RS00890 fa57b6dea1bf7cf87f3dbb4e050088cc 203 PANTHER PTHR10681:SF68 73 190 9.9E-15 T 22-04-2016 MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 Gene3D G3DSA:3.40.50.970 4 186 1.7E-54 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 Pfam PF02779 Transketolase, pyrimidine binding domain 11 173 1.3E-31 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 SUPERFAMILY SSF52518 2 175 5.3E-51 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 SUPERFAMILY SSF52922 182 314 6.94E-36 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 Gene3D G3DSA:3.40.50.920 187 314 1.3E-38 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 PANTHER PTHR11624:SF2 12 317 1.1E-105 T 22-04-2016 MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 SMART SM00861 10 175 3.8E-42 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 PANTHER PTHR11624 12 317 1.1E-105 T 22-04-2016 IPR033247 Transketolase family MED134_RS12935 49b84f26ef7e5a3ac4da827234f3d799 317 Pfam PF02780 Transketolase, C-terminal domain 186 306 1.9E-31 T 22-04-2016 IPR033248 Transketolase, C-terminal domain MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Pfam PF01330 RuvA N terminal domain 1 61 1.3E-22 T 22-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Gene3D G3DSA:1.10.150.20 67 138 5.9E-27 T 22-04-2016 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Pfam PF07499 RuvA, C-terminal domain 149 193 6.0E-13 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 193 27.698 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Gene3D G3DSA:1.10.8.10 139 193 2.4E-22 T 22-04-2016 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Gene3D G3DSA:2.40.50.140 1 63 3.3E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 SUPERFAMILY SSF47781 64 133 5.34E-19 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 Pfam PF14520 Helix-hairpin-helix domain 71 129 4.6E-16 T 22-04-2016 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 SUPERFAMILY SSF50249 1 62 5.14E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 PANTHER PTHR33796 2 193 9.8E-64 T 22-04-2016 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 SUPERFAMILY SSF46929 146 193 7.19E-14 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MED134_RS11270 bba19a1ba2e3719160bf9fb8a9bbeeae 193 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 193 1.3E-46 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 SUPERFAMILY SSF52540 4 222 6.16E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 220 3.5E-71 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 Hamap MF_00238 Cytidylate kinase [cmk]. 3 226 31.966 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 Gene3D G3DSA:3.40.50.300 2 224 2.3E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 Pfam PF02224 Cytidylate kinase 5 223 1.7E-67 T 22-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 MED134_RS04400 2b06993d5e0c5f52f535cc719d224fa4 230 PANTHER PTHR21299 5 230 3.1E-58 T 22-04-2016 MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 22 75 1.0E-14 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 SMART SM01234 8 75 1.1E-35 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 20.786 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 12 82 8.3E-26 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 PANTHER PTHR33383 12 78 1.3E-33 T 22-04-2016 MED134_RS05055 551838d2b2d161e9e2b9da4add00d521 84 Pfam PF01809 Haemolytic domain 12 75 1.3E-26 T 22-04-2016 IPR002696 Putative membrane protein insertion efficiency factor MED134_RS04025 03f69ff7113dc79e9a7db274320fbcc4 210 PANTHER PTHR30086 2 206 4.7E-75 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS04025 03f69ff7113dc79e9a7db274320fbcc4 210 Pfam PF01810 LysE type translocator 15 206 2.2E-32 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS04025 03f69ff7113dc79e9a7db274320fbcc4 210 PIRSF PIRSF006324 1 209 3.0E-48 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS04025 03f69ff7113dc79e9a7db274320fbcc4 210 PANTHER PTHR30086:SF7 2 206 4.7E-75 T 22-04-2016 MED134_RS01470 5071ce246ad5be3fe52fcc75d0093274 324 Gene3D G3DSA:3.40.910.10 6 322 2.8E-76 T 22-04-2016 IPR002773 Deoxyhypusine synthase GO:0008612 UniPathway: UPA00354 MED134_RS01470 5071ce246ad5be3fe52fcc75d0093274 324 SUPERFAMILY SSF52467 6 323 3.27E-82 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain MED134_RS01470 5071ce246ad5be3fe52fcc75d0093274 324 PANTHER PTHR11703 39 319 4.4E-49 T 22-04-2016 IPR002773 Deoxyhypusine synthase GO:0008612 UniPathway: UPA00354 MED134_RS01470 5071ce246ad5be3fe52fcc75d0093274 324 Pfam PF01916 Deoxyhypusine synthase 16 320 2.4E-41 T 22-04-2016 IPR002773 Deoxyhypusine synthase GO:0008612 UniPathway: UPA00354 MED134_RS13995 52614ca2683fbf86ab325264ca23f055 178 Gene3D G3DSA:3.40.50.300 3 173 3.8E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13995 52614ca2683fbf86ab325264ca23f055 178 Pfam PF13521 AAA domain 4 168 1.0E-41 T 22-04-2016 MED134_RS13995 52614ca2683fbf86ab325264ca23f055 178 SUPERFAMILY SSF52540 2 173 9.51E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS12105 1a52da3ac18196dc883861d6a56523d2 164 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 66 - T 22-04-2016 IPR010916 TonB box, conserved site MED134_RS06615 df9e0829d6661526aa7630441f441440 253 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 44 237 3.7E-32 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS06615 df9e0829d6661526aa7630441f441440 253 PANTHER PTHR39200:SF1 1 251 9.6E-15 T 22-04-2016 MED134_RS06615 df9e0829d6661526aa7630441f441440 253 PANTHER PTHR39200 1 251 9.6E-15 T 22-04-2016 MED134_RS05525 27b52f3bd638842558da86e2011a9159 284 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 222 282 5.6E-10 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 SUPERFAMILY SSF51230 64 109 9.57E-7 T 22-04-2016 IPR011053 Single hybrid motif MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PANTHER PTHR30386:SF8 141 399 2.5E-30 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PANTHER PTHR30386:SF8 1 124 2.5E-30 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 Gene3D G3DSA:2.40.50.100 284 321 5.2E-13 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 Gene3D G3DSA:2.40.50.100 65 102 5.2E-13 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 Pfam PF13533 Biotin-lipoyl like 72 110 2.7E-11 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PANTHER PTHR30386 141 399 2.5E-30 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PANTHER PTHR30386 1 124 2.5E-30 T 22-04-2016 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 82 102 2.6E-6 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 304 325 2.6E-6 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MED134_RS06340 f5c05a294165b8500a775796e9c4e958 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 337 361 2.6E-6 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MED134_RS03125 3c79ebc24054f6b6a9a14e02a10aa05b 222 Pfam PF02698 DUF218 domain 51 170 1.5E-25 T 22-04-2016 IPR003848 Domain of unknown function DUF218 MED134_RS03125 3c79ebc24054f6b6a9a14e02a10aa05b 222 PANTHER PTHR30336 1 207 1.2E-66 T 22-04-2016 MED134_RS03125 3c79ebc24054f6b6a9a14e02a10aa05b 222 PANTHER PTHR30336:SF0 1 207 1.2E-66 T 22-04-2016 MED134_RS03125 3c79ebc24054f6b6a9a14e02a10aa05b 222 Gene3D G3DSA:3.40.50.620 43 166 3.4E-12 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS01410 ca55f28f714232923518990f736cf38e 412 Pfam PF13579 Glycosyl transferase 4-like domain 16 203 4.3E-15 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS01410 ca55f28f714232923518990f736cf38e 412 PANTHER PTHR12526 1 405 6.5E-35 T 22-04-2016 MED134_RS01410 ca55f28f714232923518990f736cf38e 412 Pfam PF00534 Glycosyl transferases group 1 223 388 3.5E-9 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS01410 ca55f28f714232923518990f736cf38e 412 SUPERFAMILY SSF53756 2 406 1.26E-44 T 22-04-2016 MED134_RS01070 e33e7335193e900b9ef9f6b365d20af9 379 SUPERFAMILY SSF55729 2 117 2.75E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01070 e33e7335193e900b9ef9f6b365d20af9 379 SUPERFAMILY SSF55729 145 363 2.75E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01070 e33e7335193e900b9ef9f6b365d20af9 379 Gene3D G3DSA:3.40.630.30 2 80 8.9E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01070 e33e7335193e900b9ef9f6b365d20af9 379 Gene3D G3DSA:3.40.630.30 306 362 8.9E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01070 e33e7335193e900b9ef9f6b365d20af9 379 PANTHER PTHR41368 1 379 5.3E-89 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 PANTHER PTHR10657 1 215 2.9E-31 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 SUPERFAMILY SSF54534 224 326 9.16E-22 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 SUPERFAMILY SSF109998 21 133 3.33E-7 T 22-04-2016 IPR027304 Trigger factor/SurA domain MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 Gene3D G3DSA:3.10.50.40 223 345 1.7E-30 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 Gene3D G3DSA:3.10.50.40 112 219 2.1E-35 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 SUPERFAMILY SSF54534 113 215 2.16E-26 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 Pfam PF13616 PPIC-type PPIASE domain 113 217 3.6E-23 T 22-04-2016 MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 261 282 - T 22-04-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site MED134_RS00840 43aaea7c0f6b53e722b03e996e06e347 643 Pfam PF00639 PPIC-type PPIASE domain 230 323 1.7E-23 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 SUPERFAMILY SSF102114 3 372 1.57E-107 T 22-04-2016 MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 Gene3D G3DSA:3.80.30.20 3 233 5.0E-40 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 PANTHER PTHR13932 3 372 1.6E-123 T 22-04-2016 MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 3 361 1.4E-85 T 22-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 Pfam PF04055 Radical SAM superfamily 6 173 3.6E-22 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 Pfam PF06969 HemN C-terminal domain 297 360 2.8E-6 T 22-04-2016 IPR010723 HemN, C-terminal MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 SMART SM00729 1 218 9.4E-52 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS10375 e3e28635b41363b9814874ba4c5a0228 377 PANTHER PTHR13932:SF5 3 372 1.6E-123 T 22-04-2016 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 SUPERFAMILY SSF50621 234 365 4.88E-40 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PANTHER PTHR30511:SF0 1 366 7.9E-108 T 22-04-2016 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 Pfam PF00842 Alanine racemase, C-terminal domain 240 362 1.1E-32 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 TIGRFAM TIGR00492 alr: alanine racemase 6 364 1.7E-89 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 SUPERFAMILY SSF51419 8 240 1.64E-60 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PANTHER PTHR30511 1 366 7.9E-108 T 22-04-2016 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 SMART SM01005 240 364 5.8E-44 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 Gene3D G3DSA:3.20.20.10 10 221 1.9E-63 T 22-04-2016 IPR029066 PLP-binding barrel MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 Pfam PF01168 Alanine racemase, N-terminal domain 8 227 7.5E-59 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 27 43 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 346 359 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 295 312 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 124 136 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 63 81 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 256 271 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 158 169 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 PRINTS PR00992 Alanine racemase signature 202 229 9.1E-44 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 Gene3D G3DSA:2.40.37.10 222 365 1.7E-46 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 MED134_RS09845 921c4d690e35294a401a5abcc33a8ad2 366 Hamap MF_01201 Alanine racemase. 1 364 28.091 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 MED134_RS08840 d815223b567558af89e3916b56db54af 563 SUPERFAMILY SSF64182 53 450 2.75E-116 T 22-04-2016 MED134_RS08840 d815223b567558af89e3916b56db54af 563 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 24 562 4.7E-159 T 22-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MED134_RS08840 d815223b567558af89e3916b56db54af 563 Pfam PF02272 DHHA1 domain 372 435 2.4E-11 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 MED134_RS08840 d815223b567558af89e3916b56db54af 563 PANTHER PTHR30255 1 563 1.5E-198 T 22-04-2016 MED134_RS08840 d815223b567558af89e3916b56db54af 563 Pfam PF01368 DHH family 79 214 1.3E-12 T 22-04-2016 IPR001667 DDH domain MED134_RS08840 d815223b567558af89e3916b56db54af 563 PANTHER PTHR30255:SF2 1 563 1.5E-198 T 22-04-2016 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 PANTHER PTHR20941:SF1 6 277 5.7E-111 T 22-04-2016 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 Pfam PF00809 Pterin binding enzyme 18 257 1.4E-72 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 SUPERFAMILY SSF51717 2 273 1.44E-92 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 5.0E-90 T 22-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 PANTHER PTHR20941 6 277 5.7E-111 T 22-04-2016 MED134_RS13540 92c41d2cb7a961037d71973b7a9fcea3 277 Gene3D G3DSA:3.20.20.20 13 274 1.4E-97 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 MED134_RS11110 f7ce56d61826348900b9c797264ac6fc 160 Gene3D G3DSA:2.20.110.10 24 143 3.5E-9 T 22-04-2016 MED134_RS11110 f7ce56d61826348900b9c797264ac6fc 160 SUPERFAMILY SSF82185 24 102 1.83E-11 T 22-04-2016 MED134_RS11110 f7ce56d61826348900b9c797264ac6fc 160 SUPERFAMILY SSF82185 85 151 2.62E-6 T 22-04-2016 MED134_RS11100 afad38c2bb226c0b63fbad893d401b11 496 Pfam PF13641 Glycosyltransferase like family 2 56 281 1.3E-28 T 22-04-2016 MED134_RS11100 afad38c2bb226c0b63fbad893d401b11 496 Gene3D G3DSA:3.90.550.10 54 298 2.6E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11100 afad38c2bb226c0b63fbad893d401b11 496 PANTHER PTHR32044 49 311 2.2E-112 T 22-04-2016 MED134_RS11100 afad38c2bb226c0b63fbad893d401b11 496 SUPERFAMILY SSF53448 56 371 2.67E-47 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11100 afad38c2bb226c0b63fbad893d401b11 496 PANTHER PTHR32044:SF10 49 311 2.2E-112 T 22-04-2016 MED134_RS09780 8e5d8fed11af938bb6994ccd97ff27fa 154 SUPERFAMILY SSF109854 11 147 6.41E-15 T 22-04-2016 MED134_RS09780 8e5d8fed11af938bb6994ccd97ff27fa 154 Gene3D G3DSA:1.20.120.450 12 56 4.5E-4 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS09780 8e5d8fed11af938bb6994ccd97ff27fa 154 Pfam PF12867 DinB superfamily 11 143 4.6E-18 T 22-04-2016 IPR024775 DinB-like domain MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 PANTHER PTHR32332 1 304 1.7E-127 T 22-04-2016 MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 SUPERFAMILY SSF51412 3 307 7.78E-74 T 22-04-2016 MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 Pfam PF03060 Nitronate monooxygenase 78 300 1.5E-45 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 Pfam PF03060 Nitronate monooxygenase 3 77 5.7E-20 T 22-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 Gene3D G3DSA:3.20.20.70 3 295 7.4E-74 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS03345 9dfbe70e34641877503592bbd04f9a77 315 PANTHER PTHR32332:SF20 1 304 1.7E-127 T 22-04-2016 MED134_RS14825 4fa15297404c3e8f2dadaeda61bb9ab0 310 Gene3D G3DSA:4.10.1080.10 127 234 1.2E-9 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS11845 382565b6dc168049341f1a5e769b8eab 169 PANTHER PTHR23091 1 169 3.6E-35 T 22-04-2016 MED134_RS11845 382565b6dc168049341f1a5e769b8eab 169 Gene3D G3DSA:3.40.630.30 1 156 2.2E-34 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS11845 382565b6dc168049341f1a5e769b8eab 169 Pfam PF00583 Acetyltransferase (GNAT) family 62 146 3.7E-14 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS11845 382565b6dc168049341f1a5e769b8eab 169 SUPERFAMILY SSF55729 1 155 1.31E-29 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS11845 382565b6dc168049341f1a5e769b8eab 169 PANTHER PTHR23091:SF257 1 169 3.6E-35 T 22-04-2016 MED134_RS04190 8c572e996221ae4548331283b2ab6d80 529 Pfam PF03739 Predicted permease YjgP/YjgQ family 1 429 5.9E-76 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 MED134_RS04190 8c572e996221ae4548331283b2ab6d80 529 PANTHER PTHR33529 1 231 2.0E-58 T 22-04-2016 MED134_RS04190 8c572e996221ae4548331283b2ab6d80 529 PANTHER PTHR33529 326 458 2.0E-58 T 22-04-2016 MED134_RS04190 8c572e996221ae4548331283b2ab6d80 529 PANTHER PTHR33529:SF2 1 231 2.0E-58 T 22-04-2016 MED134_RS04190 8c572e996221ae4548331283b2ab6d80 529 PANTHER PTHR33529:SF2 326 458 2.0E-58 T 22-04-2016 MED134_RS02925 5d41ad95dfe141a6e30650f833bb61d3 345 Pfam PF01594 Domain of unknown function DUF20 13 329 1.1E-41 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like MED134_RS02925 5d41ad95dfe141a6e30650f833bb61d3 345 PANTHER PTHR21716:SF13 1 344 1.9E-48 T 22-04-2016 MED134_RS02925 5d41ad95dfe141a6e30650f833bb61d3 345 PANTHER PTHR21716 1 344 1.9E-48 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 309 6.4E-102 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 SMART SM01400 8 123 1.1E-63 T 22-04-2016 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 22-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 SUPERFAMILY SSF53271 72 302 3.69E-56 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 PANTHER PTHR10210:SF41 1 309 9.7E-137 T 22-04-2016 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 PANTHER PTHR10210 1 309 9.7E-137 T 22-04-2016 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 Gene3D G3DSA:3.40.50.2020 5 161 3.6E-63 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 Pfam PF14572 Phosphoribosyl synthetase-associated domain 203 310 1.2E-20 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 Gene3D G3DSA:3.40.50.2020 162 287 7.7E-43 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like MED134_RS08305 56fa1ad0f439c2f8d14d962f46e0255e 313 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 123 1.0E-40 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PANTHER PTHR30295:SF6 1 155 2.7E-48 T 22-04-2016 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 Gene3D G3DSA:1.20.1260.10 2 155 1.8E-54 T 22-04-2016 IPR012347 Ferritin-related MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 60 76 1.5E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 36 52 1.5E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 131 149 1.5E-12 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PANTHER PTHR30295 1 155 2.7E-48 T 22-04-2016 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 SUPERFAMILY SSF47240 2 155 1.38E-43 T 22-04-2016 IPR009078 Ferritin-like superfamily MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 Pfam PF00210 Ferritin-like domain 17 156 5.0E-25 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 PIRSF PIRSF005900 1 159 1.7E-44 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MED134_RS01325 e60f9c6a1c2945a940cbc988d6a60c68 163 ProSitePatterns PS00818 Dps protein family signature 1. 36 52 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 SUPERFAMILY SSF46785 2 117 1.02E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 PIRSF PIRSF019455 1 123 1.6E-27 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 PANTHER PTHR34134:SF1 1 115 8.1E-27 T 22-04-2016 MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 Pfam PF03965 Penicillinase repressor 3 115 3.4E-28 T 22-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 PANTHER PTHR34134 1 115 8.1E-27 T 22-04-2016 MED134_RS10440 d26f39d1d14cfbbcebdea559dd481087 123 Gene3D G3DSA:1.10.10.10 2 74 6.9E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS14665 6015da1bd068ef2714013a0c6af3c07f 231 Gene3D G3DSA:3.40.30.10 63 187 9.2E-14 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14665 6015da1bd068ef2714013a0c6af3c07f 231 SUPERFAMILY SSF52833 64 191 2.38E-12 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14665 6015da1bd068ef2714013a0c6af3c07f 231 Pfam PF00578 AhpC/TSA family 69 182 7.7E-8 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 SUPERFAMILY SSF55120 7 183 1.92E-27 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 PANTHER PTHR21600 133 180 7.0E-39 T 22-04-2016 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 PANTHER PTHR21600 7 113 7.0E-39 T 22-04-2016 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 PANTHER PTHR21600:SF23 133 180 7.0E-39 T 22-04-2016 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 PANTHER PTHR21600:SF23 7 113 7.0E-39 T 22-04-2016 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 9 183 5.2E-36 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 Pfam PF00849 RNA pseudouridylate synthase 9 156 7.9E-13 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS01820 21644706b521bcf853b9134f13ae7788 190 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 45 59 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 PANTHER PTHR11019:SF61 117 291 1.3E-37 T 22-04-2016 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 SUPERFAMILY SSF46689 245 291 2.96E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 Gene3D G3DSA:1.10.10.60 190 242 2.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 261 276 6.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 292 6.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 SMART SM00342 209 292 5.8E-27 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 Pfam PF12833 Helix-turn-helix domain 215 292 2.8E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 Gene3D G3DSA:1.10.10.60 245 291 5.3E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 246 288 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MED134_RS08660 a84bb3cc24de0dd44db948363eb272a1 296 PANTHER PTHR11019 117 291 1.3E-37 T 22-04-2016 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 106 317 3.5E-34 T 22-04-2016 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 302 313 3.7E-9 T 22-04-2016 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 165 179 3.7E-9 T 22-04-2016 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 251 265 3.7E-9 T 22-04-2016 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 142 161 3.7E-9 T 22-04-2016 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 186 202 3.7E-9 T 22-04-2016 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 Gene3D G3DSA:3.90.15.10 108 239 2.4E-40 T 22-04-2016 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 Gene3D G3DSA:1.20.120.380 252 333 8.9E-21 T 22-04-2016 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 SUPERFAMILY SSF55869 48 102 4.97E-15 T 22-04-2016 MED134_RS04820 cc446ccd556eaacf125713332cc34ca5 359 SUPERFAMILY SSF56349 98 322 2.88E-62 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS12425 31f21dea2b2e50bdcff3805be19dd70a 365 PIRSF PIRSF015921 2 365 1.1E-79 T 22-04-2016 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 MED134_RS12425 31f21dea2b2e50bdcff3805be19dd70a 365 Pfam PF00487 Fatty acid desaturase 64 340 5.0E-41 T 22-04-2016 IPR005804 Fatty acid desaturase domain GO:0006629 MED134_RS12425 31f21dea2b2e50bdcff3805be19dd70a 365 PANTHER PTHR19353 14 361 1.8E-70 T 22-04-2016 MED134_RS12425 31f21dea2b2e50bdcff3805be19dd70a 365 PANTHER PTHR19353:SF14 14 361 1.8E-70 T 22-04-2016 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 Pfam PF01266 FAD dependent oxidoreductase 16 369 5.2E-36 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 PANTHER PTHR13847 14 370 6.9E-35 T 22-04-2016 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 SUPERFAMILY SSF51905 5 110 1.2E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 SUPERFAMILY SSF51905 166 287 1.2E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 PANTHER PTHR13847:SF44 14 370 6.9E-35 T 22-04-2016 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 Gene3D G3DSA:3.50.50.60 15 77 2.2E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS11115 fe3fa4fa91da3816d1c36037b65ac8ea 371 Gene3D G3DSA:3.50.50.60 140 294 2.2E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS14715 6a7397186fa2199b6d75d7b53d24f6b1 1256 SUPERFAMILY SSF49299 427 504 2.75E-5 T 22-04-2016 IPR000601 PKD domain MED134_RS14715 6a7397186fa2199b6d75d7b53d24f6b1 1256 Pfam PF13585 C-terminal domain of CHU protein family 1165 1253 1.1E-19 T 22-04-2016 MED134_RS12650 b09d844e8caba0ff006d0cd0b182090e 436 Gene3D G3DSA:1.25.40.10 164 302 1.7E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12650 b09d844e8caba0ff006d0cd0b182090e 436 Gene3D G3DSA:1.25.40.10 341 411 1.7E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12650 b09d844e8caba0ff006d0cd0b182090e 436 Gene3D G3DSA:1.25.40.10 77 163 9.7E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS12650 b09d844e8caba0ff006d0cd0b182090e 436 SUPERFAMILY SSF48452 157 313 5.88E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS08525 4f67280fbc29221a7d7a03ba524c3995 274 PANTHER PTHR10245 6 129 8.1E-12 T 22-04-2016 MED134_RS08525 4f67280fbc29221a7d7a03ba524c3995 274 SUPERFAMILY SSF47413 2 68 1.3E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS08525 4f67280fbc29221a7d7a03ba524c3995 274 SMART SM00530 10 65 3.9E-13 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS08525 4f67280fbc29221a7d7a03ba524c3995 274 Gene3D G3DSA:1.10.260.40 5 69 2.3E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS08525 4f67280fbc29221a7d7a03ba524c3995 274 Pfam PF01381 Helix-turn-helix 11 65 4.8E-13 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS04435 68f6efe02ff7c5636f0e661e0ae85942 270 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 35 171 7.9E-16 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS00015 fbf2dc9f9df7e76c0961a99ae83bfa0d 314 Pfam PF11751 Protein of unknown function (DUF3308) 21 299 1.4E-95 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS00015 fbf2dc9f9df7e76c0961a99ae83bfa0d 314 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 1 300 2.6E-86 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS12040 149678bc3e90a187a4cfcec2a2f83f61 245 Gene3D G3DSA:3.30.1380.10 43 132 7.4E-4 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain MED134_RS12040 149678bc3e90a187a4cfcec2a2f83f61 245 PANTHER PTHR34385:SF1 50 237 3.6E-36 T 22-04-2016 MED134_RS12040 149678bc3e90a187a4cfcec2a2f83f61 245 PANTHER PTHR34385 50 237 3.6E-36 T 22-04-2016 MED134_RS12040 149678bc3e90a187a4cfcec2a2f83f61 245 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 51 194 1.6E-34 T 22-04-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MED134_RS12040 149678bc3e90a187a4cfcec2a2f83f61 245 SUPERFAMILY SSF55166 44 192 1.49E-23 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain MED134_RS06440 3c40e17c326631624777bf8f5c48461e 373 Pfam PF02684 Lipid-A-disaccharide synthetase 4 351 8.8E-85 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS06440 3c40e17c326631624777bf8f5c48461e 373 SUPERFAMILY SSF53756 1 334 2.32E-26 T 22-04-2016 MED134_RS06440 3c40e17c326631624777bf8f5c48461e 373 PANTHER PTHR30372 1 367 8.1E-96 T 22-04-2016 MED134_RS06440 3c40e17c326631624777bf8f5c48461e 373 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 364 9.6E-74 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 MED134_RS06440 3c40e17c326631624777bf8f5c48461e 373 PANTHER PTHR30372:SF0 1 367 8.1E-96 T 22-04-2016 MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 PANTHER PTHR23088:SF28 6 254 2.0E-80 T 22-04-2016 MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 PANTHER PTHR23088 6 254 2.0E-80 T 22-04-2016 MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 SUPERFAMILY SSF56317 3 252 2.22E-59 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 22-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 Gene3D G3DSA:3.60.110.10 3 255 3.1E-57 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS08075 bab046aec61fe3c57d3866026365e5ab 259 Pfam PF00795 Carbon-nitrogen hydrolase 8 244 9.1E-33 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS10750 37936ed43db645b08d8bb0d7a23bac81 325 SUPERFAMILY SSF56801 69 314 3.89E-6 T 22-04-2016 MED134_RS10750 37936ed43db645b08d8bb0d7a23bac81 325 Pfam PF04443 Acyl-protein synthetase, LuxE 156 322 1.3E-6 T 22-04-2016 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723|UniPathway: UPA00569 MED134_RS10750 37936ed43db645b08d8bb0d7a23bac81 325 Pfam PF04443 Acyl-protein synthetase, LuxE 13 85 3.1E-6 T 22-04-2016 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723|UniPathway: UPA00569 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 SUPERFAMILY SSF50447 2 202 9.71E-72 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 202 5.5E-80 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 ProSitePatterns PS00474 Ribosomal protein L3 signature. 98 121 - T 22-04-2016 IPR019926 Ribosomal protein L3, conserved site MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 203 35.684 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 Gene3D G3DSA:2.40.30.10 156 202 7.2E-10 T 22-04-2016 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 Gene3D G3DSA:2.40.30.10 3 32 7.2E-10 T 22-04-2016 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 Pfam PF00297 Ribosomal protein L3 93 180 4.0E-14 T 22-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 Gene3D G3DSA:4.10.960.10 78 155 1.9E-29 T 22-04-2016 MED134_RS12235 34225053fc14edd3245b5636e41d7e22 203 PANTHER PTHR11229 1 202 2.2E-102 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS10965 9625d1c77d56d6c24a2d8f3a7127c17b 424 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 12 405 1.7E-77 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MED134_RS10965 9625d1c77d56d6c24a2d8f3a7127c17b 424 Pfam PF05525 Branched-chain amino acid transport protein 4 416 1.9E-90 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MED134_RS10965 9625d1c77d56d6c24a2d8f3a7127c17b 424 PANTHER PTHR30588:SF0 1 423 6.9E-101 T 22-04-2016 MED134_RS10965 9625d1c77d56d6c24a2d8f3a7127c17b 424 PANTHER PTHR30588 1 423 6.9E-101 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 PANTHER PTHR24220 6 229 4.2E-123 T 22-04-2016 MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 SMART SM00382 33 220 3.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 SUPERFAMILY SSF52540 4 223 1.52E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 Pfam PF00005 ABC transporter 24 172 6.4E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 Gene3D G3DSA:3.40.50.300 3 223 3.4E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS13325 aa0dfd8e51456daf9e8adb3d8367aadc 229 PANTHER PTHR24220:SF578 6 229 4.2E-123 T 22-04-2016 MED134_RS14750 02b2e9d5f9114b58a4372e920def3ba6 358 PANTHER PTHR12526 92 358 1.3E-26 T 22-04-2016 MED134_RS14750 02b2e9d5f9114b58a4372e920def3ba6 358 SUPERFAMILY SSF53756 9 358 8.37E-43 T 22-04-2016 MED134_RS14750 02b2e9d5f9114b58a4372e920def3ba6 358 Gene3D G3DSA:3.40.50.2000 175 326 2.7E-14 T 22-04-2016 MED134_RS14750 02b2e9d5f9114b58a4372e920def3ba6 358 Pfam PF00534 Glycosyl transferases group 1 181 326 3.7E-21 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS04345 a374676f37074c5206a4749796be87fa 226 Pfam PF12804 MobA-like NTP transferase domain 4 128 7.9E-16 T 22-04-2016 IPR025877 MobA-like NTP transferase MED134_RS04345 a374676f37074c5206a4749796be87fa 226 Gene3D G3DSA:3.90.550.10 2 225 1.8E-22 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04345 a374676f37074c5206a4749796be87fa 226 SUPERFAMILY SSF53448 2 225 1.35E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 PANTHER PTHR24220 11 225 8.8E-73 T 22-04-2016 MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 SMART SM00382 38 226 1.9E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 Pfam PF00005 ABC transporter 30 177 1.1E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 PANTHER PTHR24220:SF73 11 225 8.8E-73 T 22-04-2016 MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 Gene3D G3DSA:3.40.50.300 6 239 9.6E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS03245 b2ddb623221c192b865ae3e71c761361 264 SUPERFAMILY SSF52540 7 236 3.32E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 SUPERFAMILY SSF117916 217 297 2.62E-21 T 22-04-2016 MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 SMART SM00932 109 194 2.8E-27 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 SMART SM00932 6 92 6.9E-21 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 PANTHER PTHR11178 112 299 7.0E-43 T 22-04-2016 MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 SUPERFAMILY SSF110836 5 91 2.48E-16 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 SUPERFAMILY SSF110836 109 195 1.26E-19 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 109 194 2.8E-25 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 91 9.3E-24 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 Pfam PF01106 NifU-like domain 228 293 1.9E-23 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 Gene3D G3DSA:3.30.1370.70 6 91 1.3E-20 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 Gene3D G3DSA:3.30.1370.70 108 195 2.6E-22 T 22-04-2016 IPR014824 Scaffold protein Nfu/NifU, N-terminal MED134_RS07575 7c97706f1d21a5dd5e0ca93d8ef54109 300 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 235 298 3.0E-13 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MED134_RS11620 7a890624e0bb9bb45d62f10643b9e8ef 153 Pfam PF05360 yiaA/B two helix domain 28 80 7.1E-20 T 22-04-2016 IPR008024 YiaAB two helix MED134_RS11620 7a890624e0bb9bb45d62f10643b9e8ef 153 Pfam PF05360 yiaA/B two helix domain 91 143 2.9E-21 T 22-04-2016 IPR008024 YiaAB two helix MED134_RS11620 7a890624e0bb9bb45d62f10643b9e8ef 153 PANTHER PTHR37290 19 143 2.0E-58 T 22-04-2016 MED134_RS11620 7a890624e0bb9bb45d62f10643b9e8ef 153 PANTHER PTHR37290:SF1 19 143 2.0E-58 T 22-04-2016 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 PANTHER PTHR11601 4 381 1.6E-126 T 22-04-2016 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 Gene3D G3DSA:3.90.1150.10 248 378 1.9E-31 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 Gene3D G3DSA:3.40.640.10 16 247 3.9E-77 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 Pfam PF00266 Aminotransferase class-V 4 372 3.2E-75 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 PIRSF PIRSF005572 1 383 6.2E-107 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 PANTHER PTHR11601:SF45 4 381 1.6E-126 T 22-04-2016 MED134_RS13900 feb8ee2094e8aa74cbc43e57a998a04b 385 SUPERFAMILY SSF53383 4 381 2.86E-92 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS02275 d874acb4a58d9b837448f343599f0f36 268 SUPERFAMILY SSF49464 37 121 6.54E-9 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS02275 d874acb4a58d9b837448f343599f0f36 268 Gene3D G3DSA:2.60.40.1120 39 127 5.2E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS02275 d874acb4a58d9b837448f343599f0f36 268 Pfam PF13715 CarboxypepD_reg-like domain 39 124 6.6E-13 T 22-04-2016 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 PIRSF PIRSF000294 32 348 2.1E-70 T 22-04-2016 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 Pfam PF03150 Di-haem cytochrome c peroxidase 63 209 3.3E-37 T 22-04-2016 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 Gene3D G3DSA:1.10.760.10 201 352 2.5E-42 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 PANTHER PTHR30600 56 351 8.0E-63 T 22-04-2016 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 Gene3D G3DSA:1.10.760.10 56 200 5.2E-36 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 PANTHER PTHR30600:SF7 56 351 8.0E-63 T 22-04-2016 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 SUPERFAMILY SSF46626 40 197 3.53E-38 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS10925 ed85e1442fefa01fed1f83e6c16bbe12 355 SUPERFAMILY SSF46626 187 342 3.62E-30 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS09305 34801e83f57c1c8d64ff9033974b5676 312 SUPERFAMILY SSF56219 33 312 3.53E-22 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS09305 34801e83f57c1c8d64ff9033974b5676 312 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 42 303 3.6E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS09305 34801e83f57c1c8d64ff9033974b5676 312 Gene3D G3DSA:3.60.10.10 39 310 1.2E-32 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 PANTHER PTHR23083 69 206 1.6E-25 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 PANTHER PTHR23083 241 345 1.6E-25 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 PANTHER PTHR23083 612 710 1.6E-25 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 PANTHER PTHR23083 499 573 1.6E-25 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 PANTHER PTHR23083 731 821 1.6E-25 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF13432 Tetratricopeptide repeat 734 778 0.013 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF13432 Tetratricopeptide repeat 506 568 0.001 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF13432 Tetratricopeptide repeat 144 201 4.4E-5 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 726 861 2.7E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 445 562 3.9E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SUPERFAMILY SSF48452 537 574 9.7E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SUPERFAMILY SSF48452 601 703 9.7E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 563 627 8.2E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SUPERFAMILY SSF81901 105 348 1.12E-13 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 105 186 1.8E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 628 690 3.8E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SUPERFAMILY SSF81901 282 535 9.68E-16 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SUPERFAMILY SSF48452 726 822 8.06E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 540 573 2.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 502 535 98.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 612 645 10.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 280 313 9.5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 245 278 320.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 833 866 160.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 139 172 32.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 796 829 100.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 315 348 4.1 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 SMART SM00028 760 793 71.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 261 444 5.6E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 277 340 2.9E-9 T 22-04-2016 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Gene3D G3DSA:1.25.40.10 187 260 5.5E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF13174 Tetratricopeptide repeat 651 682 0.097 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS13655 53f4f791fd93e819551c2d81992b04c4 1006 Pfam PF13174 Tetratricopeptide repeat 613 645 5.2E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 PANTHER PTHR11374 1 463 0.0 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Gene3D G3DSA:3.40.50.720 4 217 7.2E-74 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Gene3D G3DSA:1.20.5.100 218 243 2.7E-14 T 22-04-2016 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 PANTHER PTHR11374:SF3 1 463 0.0 T 22-04-2016 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 SMART SM00984 333 448 7.7E-40 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 SUPERFAMILY SSF48179 215 314 2.55E-28 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 SUPERFAMILY SSF52413 318 459 2.75E-34 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 191 1.6E-59 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 443 1.6E-102 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Gene3D G3DSA:3.40.50.720 246 464 9.6E-89 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 215 309 2.7E-31 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 PIRSF PIRSF500133 1 464 1.1E-238 T 22-04-2016 IPR028356 UDP-glucose 6-dehydrogenase, eukaryotic type GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 SUPERFAMILY SSF51735 4 206 1.69E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 334 447 2.0E-33 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 MED134_RS01370 132de5acd498e172bbd93884c72bfe8c 464 PIRSF PIRSF000124 4 463 5.8E-132 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 MED134_RS09225 913f1f72dff1cd015e0c7df54ec7b6a1 497 Pfam PF03321 GH3 auxin-responsive promoter 185 487 6.8E-55 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS09225 913f1f72dff1cd015e0c7df54ec7b6a1 497 Pfam PF03321 GH3 auxin-responsive promoter 19 171 9.5E-31 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS09225 913f1f72dff1cd015e0c7df54ec7b6a1 497 PANTHER PTHR31901 18 493 1.4E-37 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS09225 913f1f72dff1cd015e0c7df54ec7b6a1 497 PANTHER PTHR31901:SF5 18 493 1.4E-37 T 22-04-2016 MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 SUPERFAMILY SSF53474 183 252 3.67E-40 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 SUPERFAMILY SSF53474 5 139 3.67E-40 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 PANTHER PTHR11614 1 269 1.7E-77 T 22-04-2016 MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 PANTHER PTHR11614:SF108 1 269 1.7E-77 T 22-04-2016 MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 Pfam PF12146 Serine aminopeptidase, S33 47 162 3.6E-11 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 Pfam PF02566 OsmC-like protein 297 400 2.5E-19 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 Gene3D G3DSA:3.30.300.20 257 403 4.8E-47 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 SUPERFAMILY SSF82784 229 403 1.96E-43 T 22-04-2016 IPR003718 OsmC/Ohr family MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 Gene3D G3DSA:3.40.50.1820 181 251 4.3E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS02340 4121a6f83c487bb03c46782a2f70cea8 404 Gene3D G3DSA:3.40.50.1820 3 137 4.3E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS07485 03162d389fbcddbfe9f48703f9edccd7 114 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 105 1.6E-28 T 22-04-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MED134_RS07485 03162d389fbcddbfe9f48703f9edccd7 114 PANTHER PTHR37309 1 110 6.6E-24 T 22-04-2016 MED134_RS07485 03162d389fbcddbfe9f48703f9edccd7 114 PANTHER PTHR37309:SF1 1 110 6.6E-24 T 22-04-2016 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 PANTHER PTHR30586:SF1 3 215 2.2E-107 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 6 210 5.3E-87 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 3 213 35.387 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 PIRSF PIRSF006102 5 215 1.2E-61 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 Pfam PF02508 Rnf-Nqr subunit, membrane protein 11 201 2.8E-56 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MED134_RS07025 6c00a3326862a4f6cbc4e57b6b8a7cf4 215 PANTHER PTHR30586 3 215 2.2E-107 T 22-04-2016 MED134_RS05935 cae518e723fc9f878999c19dde1141bd 157 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 150 5.3E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 14 290 22.255 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 PANTHER PTHR11609:SF9 3 309 6.8E-91 T 22-04-2016 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 ProSitePatterns PS01058 SAICAR synthetase signature 2. 196 204 - T 22-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 PANTHER PTHR11609 3 309 6.8E-91 T 22-04-2016 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 Pfam PF01259 SAICAR synthetase 16 257 1.9E-85 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 SUPERFAMILY SSF56104 7 293 2.84E-93 T 22-04-2016 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 Gene3D G3DSA:3.30.200.20 7 104 4.5E-38 T 22-04-2016 MED134_RS04825 32abc090a166b18ed36073dae46203cc 315 Gene3D G3DSA:3.30.470.20 105 235 1.3E-48 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 SUPERFAMILY SSF52540 39 190 3.45E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 PANTHER PTHR30160:SF13 2 338 9.2E-67 T 22-04-2016 MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 5 331 3.3E-81 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 2 334 26.242 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 14 325 4.2E-45 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 MED134_RS05885 a77e4c6ca3a5a5e4b400e68f8df25a43 339 PANTHER PTHR30160 2 338 9.2E-67 T 22-04-2016 MED134_RS10890 7050aaeb433772a1c679f00c8f8b3b7e 481 PANTHER PTHR30508 4 481 0.0 T 22-04-2016 MED134_RS10890 7050aaeb433772a1c679f00c8f8b3b7e 481 PANTHER PTHR30508:SF1 4 481 0.0 T 22-04-2016 MED134_RS10890 7050aaeb433772a1c679f00c8f8b3b7e 481 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 452 1.4E-67 T 22-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MED134_RS10890 7050aaeb433772a1c679f00c8f8b3b7e 481 SUPERFAMILY SSF101960 37 478 3.79E-139 T 22-04-2016 MED134_RS10890 7050aaeb433772a1c679f00c8f8b3b7e 481 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 16 472 1.4E-189 T 22-04-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MED134_RS13370 ed6fe0463eab94899ef70179019c40c1 312 Pfam PF00535 Glycosyl transferase family 2 4 139 3.1E-27 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13370 ed6fe0463eab94899ef70179019c40c1 312 Gene3D G3DSA:3.90.550.10 1 197 2.0E-40 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13370 ed6fe0463eab94899ef70179019c40c1 312 PANTHER PTHR22916 1 309 2.1E-36 T 22-04-2016 MED134_RS13370 ed6fe0463eab94899ef70179019c40c1 312 SUPERFAMILY SSF53448 2 231 1.21E-40 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 8 723 8.9E-256 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 PANTHER PTHR31998 1 733 0.0 T 22-04-2016 MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 PIRSF PIRSF001265 1 728 1.7E-251 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 PANTHER PTHR31998:SF0 1 733 0.0 T 22-04-2016 MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 3 721 23.679 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 MED134_RS07185 2c6d072d9ffbc3e514d0e10d4b42d4ab 809 Pfam PF03030 Inorganic H+ pyrophosphatase 14 716 6.2E-258 T 22-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 MED134_RS03390 b105aa53077846d7834b92e7bf03000b 236 Pfam PF13489 Methyltransferase domain 58 159 7.0E-9 T 22-04-2016 MED134_RS03390 b105aa53077846d7834b92e7bf03000b 236 SUPERFAMILY SSF53335 53 221 4.48E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS03390 b105aa53077846d7834b92e7bf03000b 236 Gene3D G3DSA:3.40.50.150 57 176 5.3E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 PANTHER PTHR24220 9 237 5.6E-126 T 22-04-2016 MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 SUPERFAMILY SSF52540 5 235 7.64E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 SMART SM00382 32 217 1.4E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 PANTHER PTHR24220:SF581 9 237 5.6E-126 T 22-04-2016 MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 Pfam PF00005 ABC transporter 25 168 4.7E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS10270 70a4e30bafb192ccdd55e1d6e3e19b91 246 Gene3D G3DSA:3.40.50.300 5 238 4.7E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS11275 bb10351067a313ca7328229eb6d92437 2489 Pfam PF14349 Motility related/secretion protein 1181 1692 8.3E-141 T 22-04-2016 IPR025684 Gliding motility protein SprA N-terminal domain MED134_RS11275 bb10351067a313ca7328229eb6d92437 2489 Pfam PF14349 Motility related/secretion protein 58 451 2.2E-59 T 22-04-2016 IPR025684 Gliding motility protein SprA N-terminal domain MED134_RS11275 bb10351067a313ca7328229eb6d92437 2489 Gene3D G3DSA:4.10.1080.10 484 541 3.6E-4 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS11275 bb10351067a313ca7328229eb6d92437 2489 TIGRFAM TIGR04189 surface_SprA: cell surface protein SprA 51 2488 0.0 T 22-04-2016 IPR026377 Cell surface SprA MED134_RS11275 bb10351067a313ca7328229eb6d92437 2489 SUPERFAMILY SSF103647 482 549 2.48E-5 T 22-04-2016 IPR028974 TSP type-3 repeat GO:0005509 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Pfam PF01266 FAD dependent oxidoreductase 4 395 2.6E-49 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 SUPERFAMILY SSF54373 269 355 1.31E-8 T 22-04-2016 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 SUPERFAMILY SSF51905 3 55 2.27E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 SUPERFAMILY SSF51905 357 414 2.27E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 SUPERFAMILY SSF51905 108 268 2.27E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Gene3D G3DSA:3.30.9.10 136 188 2.6E-5 T 22-04-2016 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Gene3D G3DSA:3.50.50.60 109 131 8.3E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Gene3D G3DSA:3.50.50.60 4 59 8.3E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Gene3D G3DSA:3.50.50.60 189 267 8.3E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 Gene3D G3DSA:3.50.50.60 357 413 8.3E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 PANTHER PTHR13847 108 413 2.6E-47 T 22-04-2016 MED134_RS07760 ffbb5819a76c991062c9741a9a7bc5d8 415 PANTHER PTHR13847 5 66 2.6E-47 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 21 1071 9.4E-181 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 TIGRFAM TIGR04057 SusC_RagA_signa: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region 216 246 9.7E-16 T 22-04-2016 IPR023997 TonB-dependent outer membrane protein SusC/RagA, conserved site UniPathway: UPA00153 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF56935 976 1071 1.36E-86 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF56935 355 443 1.36E-86 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF56935 881 924 1.36E-86 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF56935 100 263 1.36E-86 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF56935 485 819 1.36E-86 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.60.40.1120 21 92 5.4E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Pfam PF13715 CarboxypepD_reg-like domain 22 104 1.0E-16 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532 207 430 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532 21 186 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532 486 532 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532 554 1069 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.170.130.10 101 240 2.5E-22 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532:SF51 207 430 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532:SF51 21 186 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532:SF51 486 532 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 PANTHER PTHR11532:SF51 554 1069 1.2E-184 T 22-04-2016 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.40.170.20 487 922 9.1E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.40.170.20 984 1071 9.1E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.40.170.20 362 430 9.1E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Gene3D G3DSA:2.40.170.20 241 281 9.1E-42 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 Pfam PF07715 TonB-dependent Receptor Plug Domain 114 240 2.9E-21 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS06540 56a315f3b664c40ce3d7a112eb7037a0 1071 SUPERFAMILY SSF49464 20 102 7.19E-17 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS09385 3f63f045f1e44a86fcf9304e8a78b328 134 PANTHER PTHR35024:SF2 20 122 1.6E-18 T 22-04-2016 MED134_RS09385 3f63f045f1e44a86fcf9304e8a78b328 134 PANTHER PTHR35024 20 122 1.6E-18 T 22-04-2016 MED134_RS09385 3f63f045f1e44a86fcf9304e8a78b328 134 Pfam PF04519 Polymer-forming cytoskeletal 19 114 2.9E-25 T 22-04-2016 IPR007607 Protein of unknown function DUF583 MED134_RS00095 4f7c2cfc75910c093e25a73f557fd17a 270 Gene3D G3DSA:3.40.50.720 1 219 7.9E-21 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS00095 4f7c2cfc75910c093e25a73f557fd17a 270 PANTHER PTHR10491 1 209 3.7E-16 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family MED134_RS00095 4f7c2cfc75910c093e25a73f557fd17a 270 Pfam PF04321 RmlD substrate binding domain 1 231 2.3E-11 T 22-04-2016 IPR029903 RmlD-like substrate binding domain MED134_RS00095 4f7c2cfc75910c093e25a73f557fd17a 270 SUPERFAMILY SSF51735 1 240 2.68E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS03120 5fe0e37274c4ffa5b6d5673d9ce30ffd 131 Pfam PF03061 Thioesterase superfamily 29 100 1.5E-16 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS03120 5fe0e37274c4ffa5b6d5673d9ce30ffd 131 SUPERFAMILY SSF54637 7 127 6.68E-34 T 22-04-2016 IPR029069 HotDog domain MED134_RS03120 5fe0e37274c4ffa5b6d5673d9ce30ffd 131 Gene3D G3DSA:3.10.129.10 7 127 3.7E-37 T 22-04-2016 IPR029069 HotDog domain MED134_RS03120 5fe0e37274c4ffa5b6d5673d9ce30ffd 131 PANTHER PTHR11049:SF8 4 128 1.5E-60 T 22-04-2016 MED134_RS03120 5fe0e37274c4ffa5b6d5673d9ce30ffd 131 PANTHER PTHR11049 4 128 1.5E-60 T 22-04-2016 MED134_RS01680 e2e1fb46af4ebfa14314853bd2387aab 93 PANTHER PTHR40077 5 90 9.3E-13 T 22-04-2016 MED134_RS01680 e2e1fb46af4ebfa14314853bd2387aab 93 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 5 88 7.2E-30 T 22-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane MED134_RS01680 e2e1fb46af4ebfa14314853bd2387aab 93 Pfam PF12823 Domain of unknown function (DUF3817) 2 89 1.2E-25 T 22-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane MED134_RS12830 0cd428b1367653e6019afd1a0614d1dd 829 Pfam PF00246 Zinc carboxypeptidase 44 208 1.0E-17 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS12830 0cd428b1367653e6019afd1a0614d1dd 829 SUPERFAMILY SSF53187 30 318 6.95E-52 T 22-04-2016 MED134_RS12830 0cd428b1367653e6019afd1a0614d1dd 829 SUPERFAMILY SSF52317 582 823 2.48E-19 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS12830 0cd428b1367653e6019afd1a0614d1dd 829 SMART SM00631 36 303 0.0035 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS12830 0cd428b1367653e6019afd1a0614d1dd 829 Gene3D G3DSA:3.40.630.10 34 268 5.5E-26 T 22-04-2016 MED134_RS11505 c866b3e41b0dee1ae589d6655678646f 166 Gene3D G3DSA:3.30.40.10 120 157 7.1E-4 T 22-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type MED134_RS11505 c866b3e41b0dee1ae589d6655678646f 166 Pfam PF01883 Domain of unknown function DUF59 14 71 1.4E-11 T 22-04-2016 IPR002744 Domain of unknown function DUF59 MED134_RS11505 c866b3e41b0dee1ae589d6655678646f 166 SUPERFAMILY SSF117916 12 100 9.81E-20 T 22-04-2016 MED134_RS11505 c866b3e41b0dee1ae589d6655678646f 166 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 19 164 9.7E-54 T 22-04-2016 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UniPathway: UPA00930 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 271 1.9E-18 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 402 8.7E-47 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 Gene3D G3DSA:2.40.50.100 64 96 6.9E-14 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 Gene3D G3DSA:2.40.50.100 185 208 6.9E-14 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 PANTHER PTHR32347 355 418 1.0E-54 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 PANTHER PTHR32347 38 336 1.0E-54 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 PANTHER PTHR32347:SF12 355 418 1.0E-54 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 PANTHER PTHR32347:SF12 38 336 1.0E-54 T 22-04-2016 MED134_RS11400 96fdf076b576e8e8a589b7a9f1821d23 426 SUPERFAMILY SSF111369 52 242 4.45E-24 T 22-04-2016 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Gene3D G3DSA:2.40.30.10 315 396 1.4E-22 T 22-04-2016 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 2 397 38.509 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Gene3D G3DSA:3.40.50.620 2 213 4.0E-87 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 2 228 2.4E-82 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Gene3D G3DSA:2.30.30.280 260 311 8.0E-21 T 22-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 PANTHER PTHR11933 254 396 3.6E-148 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 PANTHER PTHR11933 1 218 3.6E-148 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Pfam PF03054 tRNA methyl transferase 2 231 1.3E-87 T 22-04-2016 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 Pfam PF03054 tRNA methyl transferase 253 396 2.0E-32 T 22-04-2016 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 SUPERFAMILY SSF52402 1 223 5.51E-48 T 22-04-2016 MED134_RS03355 172ea47d0f6f4c87b8f638159026a966 397 SUPERFAMILY SSF52402 263 310 5.51E-48 T 22-04-2016 MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 Gene3D G3DSA:3.30.1320.10 3 83 4.7E-31 T 22-04-2016 IPR023803 Ribosomal protein S16 domain MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 SUPERFAMILY SSF54565 3 101 4.45E-33 T 22-04-2016 IPR023803 Ribosomal protein S16 domain MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.803 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 Pfam PF00886 Ribosomal protein S16 9 67 1.5E-22 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 PANTHER PTHR12919 2 165 7.3E-38 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS07595 d8f1847b9fa0751fc58359c7feb782e2 172 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 78 1.4E-29 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS06635 5f74d92f2a21ef94aab2c85b00d71478 419 Pfam PF07244 Surface antigen variable number repeat 23 92 2.0E-4 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 MED134_RS02870 e3170ac4bdce3d06cf160f3e3ed0a2f3 227 PANTHER PTHR36452 1 227 5.0E-34 T 22-04-2016 MED134_RS02870 e3170ac4bdce3d06cf160f3e3ed0a2f3 227 Pfam PF09365 Conserved hypothetical protein (DUF2461) 9 212 8.0E-60 T 22-04-2016 IPR012808 Conserved hypothetical protein CHP02453 MED134_RS02870 e3170ac4bdce3d06cf160f3e3ed0a2f3 227 PANTHER PTHR36452:SF1 1 227 5.0E-34 T 22-04-2016 MED134_RS02870 e3170ac4bdce3d06cf160f3e3ed0a2f3 227 PIRSF PIRSF028451 1 221 2.1E-50 T 22-04-2016 IPR015996 Uncharacterised conserved protein UCP028451 MED134_RS02870 e3170ac4bdce3d06cf160f3e3ed0a2f3 227 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 7 217 2.2E-51 T 22-04-2016 IPR012808 Conserved hypothetical protein CHP02453 MED134_RS09570 823d7818e136e20a7df7aec22c8ca271 329 Pfam PF01261 Xylose isomerase-like TIM barrel 70 268 2.7E-15 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09570 823d7818e136e20a7df7aec22c8ca271 329 SUPERFAMILY SSF51658 44 317 2.23E-40 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09570 823d7818e136e20a7df7aec22c8ca271 329 Gene3D G3DSA:3.20.20.150 46 319 1.6E-37 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09570 823d7818e136e20a7df7aec22c8ca271 329 PANTHER PTHR12110 63 329 2.3E-16 T 22-04-2016 MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 Gene3D G3DSA:3.30.70.890 193 303 4.8E-4 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 SUPERFAMILY SSF54211 8 159 8.35E-6 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 PRINTS PR00960 LmbP protein signature 91 112 2.2E-7 T 22-04-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478|UniPathway: UPA00543|UniPathway: UPA00977 MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 PRINTS PR00960 LmbP protein signature 269 288 2.2E-7 T 22-04-2016 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0008152|GO:0016301 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478|UniPathway: UPA00543|UniPathway: UPA00977 MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 SUPERFAMILY SSF55060 182 309 7.67E-15 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain MED134_RS10680 f58b8c89f0ec0c9372db40b6548108dd 312 Gene3D G3DSA:3.30.230.10 40 192 3.6E-8 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SUPERFAMILY SSF49464 39 109 7.46E-6 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 PANTHER PTHR34220 498 729 1.5E-41 T 22-04-2016 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Gene3D G3DSA:2.60.40.1120 39 97 1.4E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SUPERFAMILY SSF48452 161 333 1.41E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Pfam PF06580 Histidine kinase 528 606 6.2E-22 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SUPERFAMILY SSF55874 589 676 2.19E-7 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Gene3D G3DSA:1.25.40.10 250 448 1.2E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Gene3D G3DSA:1.25.40.10 129 249 2.8E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Pfam PF13181 Tetratricopeptide repeat 276 306 0.092 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Pfam PF13181 Tetratricopeptide repeat 171 197 0.1 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SMART SM00028 362 395 98.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SMART SM00028 276 309 26.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SMART SM00028 166 199 3.3 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 SUPERFAMILY SSF48452 311 440 1.16E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07555 01c5cd3d741b159f7348d56dfdff8218 732 Gene3D G3DSA:3.30.565.10 583 730 1.4E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 7.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 7.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 7.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 SMART SM00388 252 320 2.3E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 SUPERFAMILY SSF55874 321 469 2.75E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423:SF518 5 10 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423:SF518 81 119 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423:SF518 231 468 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 Gene3D G3DSA:1.10.287.130 244 316 8.3E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 SMART SM00387 360 470 1.3E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 SUPERFAMILY SSF47384 241 318 1.43E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423 5 10 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423 81 119 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 PANTHER PTHR24423 231 468 5.8E-59 T 22-04-2016 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 Gene3D G3DSA:3.30.565.10 323 468 9.9E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 Pfam PF05227 CHASE3 domain 38 172 3.9E-19 T 22-04-2016 IPR007891 CHASE3 MED134_RS14720 2d9d585a76bd081a4bf43494289c17ea 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 469 1.4E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 PANTHER PTHR10772 4 91 3.0E-41 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 22-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 Pfam PF00166 Chaperonin 10 Kd subunit 4 91 6.2E-32 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 PRINTS PR00297 10kDa chaperonin signature 5 20 5.77E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 PRINTS PR00297 10kDa chaperonin signature 27 48 5.77E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 PRINTS PR00297 10kDa chaperonin signature 57 69 5.77E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 PRINTS PR00297 10kDa chaperonin signature 78 91 5.77E-30 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 SUPERFAMILY SSF50129 2 91 7.16E-31 T 22-04-2016 IPR011032 GroES-like MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 Hamap MF_00580 10 kDa chaperonin [groS]. 4 91 21.335 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 SMART SM00883 4 91 1.2E-48 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS06150 7fb7703d8490a85f882bc4e8634c96bd 91 Gene3D G3DSA:2.30.33.40 4 91 4.4E-33 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MED134_RS01685 76abfe05b77907c0fcc3d52353244bca 121 Pfam PF09685 Domain of unknown function (DUF4870) 13 120 6.8E-31 T 22-04-2016 IPR019109 Protein of unknown function DUF4870 MED134_RS05965 f80fdacd073825b1c6f12d6605bfd8f9 373 PANTHER PTHR30068:SF3 24 372 6.1E-70 T 22-04-2016 MED134_RS05965 f80fdacd073825b1c6f12d6605bfd8f9 373 SUPERFAMILY SSF69593 85 240 9.81E-5 T 22-04-2016 MED134_RS05965 f80fdacd073825b1c6f12d6605bfd8f9 373 PANTHER PTHR30068 24 372 6.1E-70 T 22-04-2016 MED134_RS09635 2b161662bbac1aca27d1f14da9bd3640 291 SMART SM00903 22 176 1.6E-8 T 22-04-2016 IPR002563 Flavin reductase like domain GO:0010181 MED134_RS09635 2b161662bbac1aca27d1f14da9bd3640 291 Gene3D G3DSA:2.30.110.10 18 192 3.7E-56 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS09635 2b161662bbac1aca27d1f14da9bd3640 291 PANTHER PTHR33798 1 223 5.9E-53 T 22-04-2016 MED134_RS09635 2b161662bbac1aca27d1f14da9bd3640 291 Pfam PF01613 Flavin reductase like domain 24 167 1.0E-14 T 22-04-2016 IPR002563 Flavin reductase like domain GO:0010181 MED134_RS09635 2b161662bbac1aca27d1f14da9bd3640 291 SUPERFAMILY SSF50475 4 194 7.36E-37 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS08000 27224f7b19822559551c77ca70687f99 301 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 2 288 1.2E-28 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MED134_RS08000 27224f7b19822559551c77ca70687f99 301 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 13 270 1.5E-16 T 22-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MED134_RS12415 0e2d9d79bd7e029b3d81f3d09b7dec92 179 SUPERFAMILY SSF56235 16 167 3.09E-7 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS12415 0e2d9d79bd7e029b3d81f3d09b7dec92 179 Gene3D G3DSA:3.60.60.10 14 167 1.4E-10 T 22-04-2016 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 MED134_RS11285 2671fff9328eff02c4d8aff24b8bc06f 110 SUPERFAMILY SSF144091 20 103 1.1E-5 T 22-04-2016 MED134_RS11285 2671fff9328eff02c4d8aff24b8bc06f 110 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 13 24 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MED134_RS11285 2671fff9328eff02c4d8aff24b8bc06f 110 Pfam PF04892 VanZ like family 13 99 3.2E-9 T 22-04-2016 IPR006976 VanZ-like MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 SUPERFAMILY SSF55486 351 586 2.04E-37 T 22-04-2016 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533:SF163 158 212 5.8E-36 T 22-04-2016 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533:SF163 1 128 5.8E-36 T 22-04-2016 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533:SF163 231 298 5.8E-36 T 22-04-2016 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533:SF163 346 586 5.8E-36 T 22-04-2016 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 Pfam PF01433 Peptidase family M1 338 471 4.6E-6 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533 158 212 5.8E-36 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533 1 128 5.8E-36 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533 231 298 5.8E-36 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 PANTHER PTHR11533 346 586 5.8E-36 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 MED134_RS12110 211396fbc96e4c2d10f7d814d7359c66 768 Gene3D G3DSA:1.10.390.10 449 587 2.5E-15 T 22-04-2016 MED134_RS09470 e9059290433e844489b435dc962e07b2 410 PANTHER PTHR21666 32 410 5.3E-21 T 22-04-2016 MED134_RS09470 e9059290433e844489b435dc962e07b2 410 Pfam PF01551 Peptidase family M23 311 403 1.4E-16 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS09470 e9059290433e844489b435dc962e07b2 410 SUPERFAMILY SSF51261 222 407 2.12E-23 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS09470 e9059290433e844489b435dc962e07b2 410 Gene3D G3DSA:2.70.70.10 264 408 1.2E-27 T 22-04-2016 MED134_RS09470 e9059290433e844489b435dc962e07b2 410 PANTHER PTHR21666:SF200 32 410 5.3E-21 T 22-04-2016 MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 Gene3D G3DSA:3.90.1150.10 282 398 1.5E-24 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 2.7E-173 T 22-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 PANTHER PTHR11601:SF17 6 403 2.4E-190 T 22-04-2016 MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 SUPERFAMILY SSF53383 3 400 6.92E-129 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 Gene3D G3DSA:3.40.640.10 35 281 7.8E-82 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 Pfam PF00266 Aminotransferase class-V 24 392 2.2E-145 T 22-04-2016 IPR000192 Aminotransferase class V domain MED134_RS10865 5cccdfbb7174e7710294fa9db781e2f5 404 PANTHER PTHR11601 6 403 2.4E-190 T 22-04-2016 MED134_RS04850 6e4428daaf0b698b555e4b68b1a2802f 191 Gene3D G3DSA:1.20.910.10 2 187 8.5E-34 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 MED134_RS04850 6e4428daaf0b698b555e4b68b1a2802f 191 SUPERFAMILY SSF48613 3 186 1.38E-31 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 MED134_RS04850 6e4428daaf0b698b555e4b68b1a2802f 191 Pfam PF01126 Heme oxygenase 103 184 7.6E-5 T 22-04-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 MED134_RS04850 6e4428daaf0b698b555e4b68b1a2802f 191 Pfam PF01126 Heme oxygenase 3 85 2.7E-9 T 22-04-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 MED134_RS07360 fc9752daebd35e59478e7d95433ff9fd 92 Pfam PF01541 GIY-YIG catalytic domain 2 73 7.6E-12 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS07360 fc9752daebd35e59478e7d95433ff9fd 92 SUPERFAMILY SSF82771 2 79 1.44E-7 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily MED134_RS00730 038e2167d725d2c1e84338f206e7567d 163 Gene3D G3DSA:1.20.1260.10 69 158 1.9E-20 T 22-04-2016 IPR012347 Ferritin-related MED134_RS00730 038e2167d725d2c1e84338f206e7567d 163 Pfam PF03713 Domain of unknown function (DUF305) 102 155 2.0E-11 T 22-04-2016 IPR005183 Domain of unknown function DUF305 MED134_RS00145 b47f6f087e5fca90101d05d0ef32cdd5 267 SMART SM00563 53 192 3.0E-13 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS00145 b47f6f087e5fca90101d05d0ef32cdd5 267 SUPERFAMILY SSF69593 24 212 7.59E-11 T 22-04-2016 MED134_RS00145 b47f6f087e5fca90101d05d0ef32cdd5 267 Gene3D G3DSA:3.40.1130.10 40 198 8.2E-5 T 22-04-2016 MED134_RS00145 b47f6f087e5fca90101d05d0ef32cdd5 267 Pfam PF01553 Acyltransferase 45 189 1.5E-8 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 PANTHER PTHR13903 1 236 6.7E-95 T 22-04-2016 IPR012093 Pirin MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 PANTHER PTHR13903:SF7 1 236 6.7E-95 T 22-04-2016 MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 PIRSF PIRSF006232 1 233 3.3E-45 T 22-04-2016 IPR012093 Pirin MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 Gene3D G3DSA:2.60.120.10 7 233 6.2E-62 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 Pfam PF02678 Pirin 13 120 8.0E-31 T 22-04-2016 IPR003829 Pirin, N-terminal domain MED134_RS14350 0160772e094843b86dbf002d04e70f83 237 SUPERFAMILY SSF51182 4 233 2.46E-65 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 Gene3D G3DSA:1.10.8.300 204 316 3.9E-33 T 22-04-2016 MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 PIRSF PIRSF002849 2 317 1.6E-118 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 173 2.8E-62 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 Gene3D G3DSA:3.40.50.300 26 189 2.2E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 PANTHER PTHR11603:SF156 17 316 6.8E-129 T 22-04-2016 MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 SUPERFAMILY SSF52540 23 295 3.29E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00855 856e0be9b4fc76826a8a35d75190b99f 317 PANTHER PTHR11603 17 316 6.8E-129 T 22-04-2016 MED134_RS06220 a9e7147aa637a3f5f02bbc8275d558f9 420 Pfam PF12704 MacB-like periplasmic core domain 26 255 2.7E-27 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS06220 a9e7147aa637a3f5f02bbc8275d558f9 420 Pfam PF02687 FtsX-like permease family 298 412 7.8E-18 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS06220 a9e7147aa637a3f5f02bbc8275d558f9 420 PANTHER PTHR30572 5 419 2.2E-61 T 22-04-2016 MED134_RS14405 65e8accb034bb29a1c26a2c65f20fc33 238 Gene3D G3DSA:3.30.1330.80 136 233 2.3E-12 T 22-04-2016 MED134_RS14405 65e8accb034bb29a1c26a2c65f20fc33 238 SUPERFAMILY SSF117856 33 237 1.99E-40 T 22-04-2016 MED134_RS14405 65e8accb034bb29a1c26a2c65f20fc33 238 Pfam PF03306 Alpha-acetolactate decarboxylase 39 233 5.9E-18 T 22-04-2016 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939|UniPathway: UPA00626 MED134_RS14405 65e8accb034bb29a1c26a2c65f20fc33 238 Gene3D G3DSA:3.30.1330.80 40 135 1.8E-5 T 22-04-2016 MED134_RS09455 bc8512e2f4c29b73ee19a41539ebcee2 339 PANTHER PTHR22572 2 330 4.3E-51 T 22-04-2016 MED134_RS09455 bc8512e2f4c29b73ee19a41539ebcee2 339 Pfam PF00483 Nucleotidyl transferase 8 238 4.3E-20 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 MED134_RS09455 bc8512e2f4c29b73ee19a41539ebcee2 339 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 292 1.6E-5 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS09455 bc8512e2f4c29b73ee19a41539ebcee2 339 Gene3D G3DSA:3.90.550.10 1 298 3.2E-54 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS09455 bc8512e2f4c29b73ee19a41539ebcee2 339 SUPERFAMILY SSF53448 1 298 9.98E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11995 5f4a5349b1d00be3dd18415e35e50870 167 Gene3D G3DSA:1.10.10.10 2 85 5.2E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS11995 5f4a5349b1d00be3dd18415e35e50870 167 PIRSF PIRSF006707 1 167 1.4E-49 T 22-04-2016 IPR026282 DNA-binding protein, MJ1563 type MED134_RS11995 5f4a5349b1d00be3dd18415e35e50870 167 PANTHER PTHR38465 1 114 1.3E-17 T 22-04-2016 MED134_RS11995 5f4a5349b1d00be3dd18415e35e50870 167 SUPERFAMILY SSF46785 4 119 4.4E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 SUPERFAMILY SSF50156 105 196 5.65E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 Pfam PF02163 Peptidase family M50 10 420 1.7E-59 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 PANTHER PTHR22939:SF78 75 434 1.2E-38 T 22-04-2016 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 7 433 5.7E-70 T 22-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 Gene3D G3DSA:2.30.42.10 100 189 3.0E-8 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 SUPERFAMILY SSF50156 219 278 9.99E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 PANTHER PTHR22939 75 434 1.2E-38 T 22-04-2016 MED134_RS10310 52b2c8c0d05768e7f98946ba3767012e 435 Gene3D G3DSA:2.30.42.10 190 284 8.3E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.170.130.10 116 238 1.2E-23 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Pfam PF13715 CarboxypepD_reg-like domain 28 106 1.4E-17 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF56935 818 862 2.2E-101 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF56935 102 260 2.2E-101 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF56935 302 390 2.2E-101 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF56935 419 755 2.2E-101 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF56935 901 952 2.2E-101 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 TIGRFAM TIGR04057 SusC_RagA_signa: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region 211 241 2.4E-19 T 22-04-2016 IPR023997 TonB-dependent outer membrane protein SusC/RagA, conserved site UniPathway: UPA00153 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.40.170.20 239 266 3.2E-55 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.40.170.20 827 852 3.2E-55 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.40.170.20 897 992 3.2E-55 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.40.170.20 311 785 3.2E-55 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 PANTHER PTHR11532:SF57 444 994 2.3E-249 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 PANTHER PTHR11532:SF57 1 356 2.3E-249 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 TIGRFAM TIGR04056 OMP_RagA_SusC: TonB-linked outer membrane protein, SusC/RagA family 26 995 1.2E-252 T 22-04-2016 IPR023996 TonB-dependent outer membrane protein, SusC/RagA UniPathway: UPA00153 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 PANTHER PTHR11532 444 994 2.3E-249 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 PANTHER PTHR11532 1 356 2.3E-249 T 22-04-2016 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 SUPERFAMILY SSF49464 26 99 3.01E-16 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Gene3D G3DSA:2.60.40.1120 28 115 1.0E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Pfam PF07715 TonB-dependent Receptor Plug Domain 114 235 1.7E-23 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS02110 2f4b63d2eae7dfe68a1b8b407673d762 996 Pfam PF00593 TonB dependent receptor 608 993 7.5E-21 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 317 339 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 116 290 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 785 793 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 369 430 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 833 909 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF56935 495 736 1.37E-24 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Gene3D G3DSA:2.60.40.1120 26 99 4.6E-8 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Gene3D G3DSA:2.40.170.20 325 486 2.1E-6 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Gene3D G3DSA:2.40.170.20 239 281 2.1E-6 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Gene3D G3DSA:2.40.170.20 540 673 2.1E-6 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Gene3D G3DSA:2.170.130.10 139 206 3.1E-4 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Pfam PF14905 Outer membrane protein beta-barrel family 452 784 3.3E-16 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 Pfam PF13715 CarboxypepD_reg-like domain 26 119 3.3E-12 T 22-04-2016 MED134_RS07435 6e82bad72d64f32e85ff30cd451d5291 926 SUPERFAMILY SSF49464 23 111 3.92E-9 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 PANTHER PTHR30270 1 350 4.1E-120 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 PIRSF PIRSF005303 10 346 4.8E-99 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 PANTHER PTHR30270:SF0 1 350 4.1E-120 T 22-04-2016 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 Gene3D G3DSA:3.90.650.10 161 344 3.2E-47 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 Pfam PF02769 AIR synthase related protein, C-terminal domain 165 325 4.9E-7 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 SUPERFAMILY SSF55326 12 152 8.02E-36 T 22-04-2016 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 SUPERFAMILY SSF56042 159 327 5.53E-35 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 15 343 28.552 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 Pfam PF00586 AIR synthase related protein, N-terminal domain 41 152 7.4E-24 T 22-04-2016 IPR016188 PurM-like, N-terminal domain MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 16 345 3.1E-96 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 MED134_RS10950 c672cbd3a6c34a397cd9a610765e304c 350 Gene3D G3DSA:3.30.1330.10 10 153 1.4E-44 T 22-04-2016 IPR016188 PurM-like, N-terminal domain MED134_RS12845 6e74b8cebd840201cc0e0397fdc61dd7 173 SUPERFAMILY SSF82185 34 71 3.79E-5 T 22-04-2016 MED134_RS12845 6e74b8cebd840201cc0e0397fdc61dd7 173 SUPERFAMILY SSF82185 101 168 3.79E-5 T 22-04-2016 MED134_RS12845 6e74b8cebd840201cc0e0397fdc61dd7 173 Gene3D G3DSA:2.20.110.10 107 170 0.001 T 22-04-2016 MED134_RS02820 89098b44d44c3e251c56128b7d004863 300 Pfam PF01904 Protein of unknown function DUF72 57 276 9.1E-47 T 22-04-2016 IPR002763 Protein of unknown function DUF72 MED134_RS02820 89098b44d44c3e251c56128b7d004863 300 PANTHER PTHR30348:SF3 40 260 4.6E-40 T 22-04-2016 MED134_RS02820 89098b44d44c3e251c56128b7d004863 300 PANTHER PTHR30348 40 260 4.6E-40 T 22-04-2016 MED134_RS02820 89098b44d44c3e251c56128b7d004863 300 SUPERFAMILY SSF117396 40 279 1.06E-61 T 22-04-2016 IPR002763 Protein of unknown function DUF72 MED134_RS02820 89098b44d44c3e251c56128b7d004863 300 Gene3D G3DSA:3.20.20.410 33 282 1.7E-63 T 22-04-2016 IPR002763 Protein of unknown function DUF72 MED134_RS01550 b01d388be6242781070183b1eb589bb7 149 Pfam PF00226 DnaJ domain 9 62 1.6E-7 T 22-04-2016 IPR001623 DnaJ domain MED134_RS01550 b01d388be6242781070183b1eb589bb7 149 SUPERFAMILY SSF46565 7 63 1.44E-10 T 22-04-2016 IPR001623 DnaJ domain MED134_RS01550 b01d388be6242781070183b1eb589bb7 149 Pfam PF13619 KTSC domain 85 136 1.3E-12 T 22-04-2016 IPR025309 KTSC domain MED134_RS01550 b01d388be6242781070183b1eb589bb7 149 Gene3D G3DSA:1.10.287.110 9 63 6.2E-12 T 22-04-2016 IPR001623 DnaJ domain MED134_RS01550 b01d388be6242781070183b1eb589bb7 149 SMART SM00271 5 67 3.2E-7 T 22-04-2016 IPR001623 DnaJ domain MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 SUPERFAMILY SSF52172 4 133 1.99E-40 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 SMART SM00448 6 119 4.3E-42 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 Pfam PF00072 Response regulator receiver domain 8 119 2.4E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 SMART SM00862 154 225 1.2E-22 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 Gene3D G3DSA:1.10.10.10 132 226 2.3E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 PANTHER PTHR26402:SF50 6 225 3.4E-84 T 22-04-2016 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 225 1.1E-21 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 SUPERFAMILY SSF46894 129 226 1.3E-26 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 Gene3D G3DSA:3.40.50.2300 2 130 1.0E-41 T 22-04-2016 MED134_RS10760 bdc460bc5b9bfa5eadeab62120715adf 227 PANTHER PTHR26402 6 225 3.4E-84 T 22-04-2016 MED134_RS14685 e8b77095f695be4721683853d5304fd3 217 Gene3D G3DSA:3.40.30.10 131 209 1.3E-7 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14685 e8b77095f695be4721683853d5304fd3 217 SUPERFAMILY SSF52833 133 208 1.48E-5 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10050 3a2c4ab53dc3fad559787258ff2d7fe2 518 Pfam PF14134 Domain of unknown function (DUF4301) 4 516 2.5E-212 T 22-04-2016 IPR025393 Domain of unknown function DUF4301 MED134_RS10050 3a2c4ab53dc3fad559787258ff2d7fe2 518 SUPERFAMILY SSF53448 165 326 8.81E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS10050 3a2c4ab53dc3fad559787258ff2d7fe2 518 SUPERFAMILY SSF53448 392 514 8.81E-18 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS06205 e75c8bf1f1bd52c31da0a372db050a0c 137 TIGRFAM TIGR04127 flavo_near_exo: exosortase F-associated protein 2 134 1.5E-50 T 22-04-2016 IPR026414 Exosortase F-associated protein MED134_RS06450 3c817097e0b73fbb4beae38b8305feab 674 Pfam PF13567 Domain of unknown function (DUF4131) 17 190 6.1E-19 T 22-04-2016 IPR025405 Domain of unknown function DUF4131 MED134_RS06450 3c817097e0b73fbb4beae38b8305feab 674 Pfam PF03772 Competence protein 232 497 2.1E-57 T 22-04-2016 IPR004477 ComEC/Rec2-related protein MED134_RS06450 3c817097e0b73fbb4beae38b8305feab 674 PANTHER PTHR30619:SF2 4 522 7.6E-62 T 22-04-2016 MED134_RS06450 3c817097e0b73fbb4beae38b8305feab 674 PANTHER PTHR30619 4 522 7.6E-62 T 22-04-2016 MED134_RS06450 3c817097e0b73fbb4beae38b8305feab 674 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 254 429 6.3E-27 T 22-04-2016 IPR004477 ComEC/Rec2-related protein MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 SUPERFAMILY SSF111304 5 200 3.79E-68 T 22-04-2016 IPR023627 Recombination protein RecR MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 Pfam PF13662 Toprim domain 82 171 1.1E-23 T 22-04-2016 IPR006171 Toprim domain MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 PANTHER PTHR30446 2 201 1.5E-103 T 22-04-2016 MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 Pfam PF02132 RecR protein 41 79 1.7E-15 T 22-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 PANTHER PTHR30446:SF0 2 201 1.5E-103 T 22-04-2016 MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 88.306 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 ProSitePatterns PS01300 RecR protein signature. 58 79 - T 22-04-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 TIGRFAM TIGR00615 recR: recombination protein RecR 5 196 2.6E-67 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MED134_RS05120 c5d4a1d8bb3c0d3741a16a185268c859 205 SMART SM00493 81 166 7.4E-8 T 22-04-2016 IPR006171 Toprim domain MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 PIRSF PIRSF002211 1 59 4.8E-26 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 6.8E-25 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 PANTHER PTHR15892:SF2 1 58 1.1E-20 T 22-04-2016 MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 SUPERFAMILY SSF55129 1 58 9.42E-21 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 Gene3D G3DSA:3.30.1390.20 1 58 1.5E-27 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.2E-17 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.567 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 MED134_RS12325 5b8c7933f6856f47ff4333d539b97a05 59 PANTHER PTHR15892 1 58 1.1E-20 T 22-04-2016 MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 Gene3D G3DSA:3.90.550.10 3 210 7.4E-48 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 Pfam PF00535 Glycosyl transferase family 2 4 179 3.4E-23 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 SUPERFAMILY SSF53448 3 249 6.14E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 PANTHER PTHR22916:SF9 157 261 4.3E-48 T 22-04-2016 MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 PANTHER PTHR22916 2 139 4.3E-48 T 22-04-2016 MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 PANTHER PTHR22916:SF9 2 139 4.3E-48 T 22-04-2016 MED134_RS05115 84e68fc80a51edef03b1b43f4ed0a863 376 PANTHER PTHR22916 157 261 4.3E-48 T 22-04-2016 MED134_RS05020 6e352deb07ec449760cb25c0a3645b60 125 Pfam PF01618 MotA/TolQ/ExbB proton channel family 38 119 2.3E-11 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 SUPERFAMILY SSF81336 201 360 5.62E-31 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 PRINTS PR00123 ATP synthase A subunit signature 288 310 3.6E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 PRINTS PR00123 ATP synthase A subunit signature 209 225 3.6E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 PRINTS PR00123 ATP synthase A subunit signature 347 362 3.6E-17 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 PANTHER PTHR11410:SF0 127 372 1.5E-47 T 22-04-2016 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 Pfam PF00119 ATP synthase A chain 153 360 4.6E-44 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 Hamap MF_01393 ATP synthase subunit a [atpB]. 130 367 11.563 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 Gene3D G3DSA:1.20.120.220 201 366 1.1E-35 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 PANTHER PTHR11410 127 372 1.5E-47 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS09400 d2ea682e9fd4f8602a138181354e1ab9 392 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 128 361 2.0E-36 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 MED134_RS14770 50dcb6eac61c48abeca94ecaea7ca7b9 926 Pfam PF05569 BlaR1 peptidase M56 45 256 4.0E-13 T 22-04-2016 IPR008756 Peptidase M56 MED134_RS14770 50dcb6eac61c48abeca94ecaea7ca7b9 926 PANTHER PTHR33446 1 175 7.8E-19 T 22-04-2016 MED134_RS14770 50dcb6eac61c48abeca94ecaea7ca7b9 926 PANTHER PTHR33446:SF2 1 175 7.8E-19 T 22-04-2016 MED134_RS13810 1217a5ca0d9228533a547edcc8f3e0d4 1038 SUPERFAMILY SSF51445 202 394 7.72E-39 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS13810 1217a5ca0d9228533a547edcc8f3e0d4 1038 SUPERFAMILY SSF51445 31 175 7.72E-39 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS13810 1217a5ca0d9228533a547edcc8f3e0d4 1038 Gene3D G3DSA:3.20.20.80 31 392 8.5E-35 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 PANTHER PTHR21588 355 845 1.7E-63 T 22-04-2016 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 SUPERFAMILY SSF141072 200 308 1.83E-5 T 22-04-2016 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 Gene3D G3DSA:2.130.10.10 657 702 1.2E-16 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 Gene3D G3DSA:2.130.10.10 792 806 1.2E-16 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 Gene3D G3DSA:2.130.10.10 494 597 1.2E-16 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 Gene3D G3DSA:2.130.10.10 299 461 1.2E-16 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 PANTHER PTHR21588:SF5 355 845 1.7E-63 T 22-04-2016 MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 SUPERFAMILY SSF51004 493 568 9.42E-16 T 22-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 SUPERFAMILY SSF51004 297 460 9.42E-16 T 22-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain MED134_RS14605 eba1a71a3ef4bab0cf6fd44e380b694d 886 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 825 886 1.8E-9 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS14395 2ffd82b9a94bd95f9f31689c3ce003e6 176 PANTHER PTHR34582 25 157 8.4E-38 T 22-04-2016 MED134_RS14395 2ffd82b9a94bd95f9f31689c3ce003e6 176 Pfam PF04239 Protein of unknown function (DUF421) 94 159 3.8E-11 T 22-04-2016 IPR007353 Protein of unknown function DUF421 MED134_RS14395 2ffd82b9a94bd95f9f31689c3ce003e6 176 Gene3D G3DSA:3.30.240.20 90 157 1.8E-15 T 22-04-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain MED134_RS14395 2ffd82b9a94bd95f9f31689c3ce003e6 176 PANTHER PTHR34582:SF1 25 157 8.4E-38 T 22-04-2016 MED134_RS10185 97e3540158e0c01d2e1d36682735772b 126 PANTHER PTHR10584:SF191 5 66 1.3E-15 T 22-04-2016 MED134_RS10185 97e3540158e0c01d2e1d36682735772b 126 PANTHER PTHR10584 5 66 1.3E-15 T 22-04-2016 MED134_RS10185 97e3540158e0c01d2e1d36682735772b 126 Pfam PF04241 Protein of unknown function (DUF423) 19 108 1.1E-24 T 22-04-2016 IPR006696 Protein of unknown function DUF423 MED134_RS03860 78cc9bf7b60b37c50330d0bbc5587efc 611 Gene3D G3DSA:2.60.450.10 56 148 1.3E-9 T 22-04-2016 MED134_RS03860 78cc9bf7b60b37c50330d0bbc5587efc 611 Gene3D G3DSA:2.60.450.10 279 379 1.8E-7 T 22-04-2016 MED134_RS03860 78cc9bf7b60b37c50330d0bbc5587efc 611 Gene3D G3DSA:2.60.450.10 153 260 4.6E-11 T 22-04-2016 MED134_RS03860 78cc9bf7b60b37c50330d0bbc5587efc 611 Pfam PF13100 OstA-like protein 54 186 2.8E-38 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal MED134_RS07155 f8151df81ce54d105d9c570ae87a8fb9 130 SUPERFAMILY SSF46458 5 124 1.61E-25 T 22-04-2016 IPR009050 Globin-like MED134_RS07155 f8151df81ce54d105d9c570ae87a8fb9 130 Gene3D G3DSA:1.10.490.10 4 113 2.7E-17 T 22-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 Pfam PF13649 Methyltransferase domain 58 151 9.9E-10 T 22-04-2016 MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 Gene3D G3DSA:3.40.50.150 26 228 1.6E-21 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 PANTHER PTHR10108:SF868 206 229 4.5E-41 T 22-04-2016 MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 PANTHER PTHR10108:SF868 34 189 4.5E-41 T 22-04-2016 MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 SUPERFAMILY SSF53335 37 244 1.67E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 PANTHER PTHR10108 206 229 4.5E-41 T 22-04-2016 MED134_RS05905 80efce9d2718e71015a02b4370821a5a 267 PANTHER PTHR10108 34 189 4.5E-41 T 22-04-2016 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 Pfam PF01207 Dihydrouridine synthase (Dus) 16 314 2.1E-86 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 PANTHER PTHR11082 3 318 8.1E-122 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 Gene3D G3DSA:3.20.20.70 13 249 4.2E-80 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 Gene3D G3DSA:1.10.1200.80 255 324 5.9E-18 T 22-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 PANTHER PTHR11082:SF25 3 318 8.1E-122 T 22-04-2016 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 13 322 8.0E-96 T 22-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 SUPERFAMILY SSF51395 13 318 6.23E-84 T 22-04-2016 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS06735 65fb0635dc15b8253a0987b0a205f09b 330 PIRSF PIRSF006621 1 328 3.2E-100 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 SUPERFAMILY SSF48498 81 190 1.78E-15 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 SUPERFAMILY SSF46689 8 71 6.98E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 Gene3D G3DSA:1.10.10.60 8 58 3.0E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 Gene3D G3DSA:1.10.357.10 59 191 1.5E-24 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.2E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.2E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 PANTHER PTHR30055:SF56 1 165 9.4E-25 T 22-04-2016 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 PANTHER PTHR30055 1 165 9.4E-25 T 22-04-2016 MED134_RS11480 ba8d2eeae5c099ec2ae405bd570b597f 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 5.2E-15 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 SUPERFAMILY SSF103481 29 125 1.7E-15 T 22-04-2016 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 SUPERFAMILY SSF103481 169 267 3.14E-11 T 22-04-2016 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 PANTHER PTHR22911:SF6 1 268 2.4E-60 T 22-04-2016 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 Pfam PF00892 EamA-like transporter family 137 262 7.2E-8 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 Pfam PF00892 EamA-like transporter family 1 124 2.0E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS06260 b7ebee678188c220379bda1002a7ef15 269 PANTHER PTHR22911 1 268 2.4E-60 T 22-04-2016 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 Gene3D G3DSA:3.40.718.10 2 331 4.9E-110 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 PANTHER PTHR30004:SF6 3 339 1.6E-127 T 22-04-2016 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 36 323 7.8E-98 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 PANTHER PTHR30004 3 339 1.6E-127 T 22-04-2016 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 326 2.1E-101 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 327 28.492 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 MED134_RS06700 d0527bf1bc217353c1a3142c8041aa55 360 SUPERFAMILY SSF53659 6 330 1.15E-89 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 Pfam PF00501 AMP-binding enzyme 20 458 3.6E-97 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 Gene3D G3DSA:3.40.50.980 41 183 1.9E-35 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 Gene3D G3DSA:3.40.50.980 324 381 7.6E-31 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 Gene3D G3DSA:3.40.50.980 184 275 7.6E-31 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 SUPERFAMILY SSF56801 327 587 8.11E-108 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 SUPERFAMILY SSF56801 25 280 8.11E-108 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 PRINTS PR00154 AMP-binding signature 172 183 3.8E-5 T 22-04-2016 IPR020459 AMP-binding MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 PRINTS PR00154 AMP-binding signature 184 192 3.8E-5 T 22-04-2016 IPR020459 AMP-binding MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 Gene3D G3DSA:2.30.38.10 386 449 1.4E-19 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 22-04-2016 IPR020845 AMP-binding, conserved site MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 PANTHER PTHR24096 29 587 1.5E-181 T 22-04-2016 MED134_RS01920 e32cafcfbba5c7e8ffe38d38fde52cb2 589 PANTHER PTHR24096:SF193 29 587 1.5E-181 T 22-04-2016 MED134_RS10150 cfd1d990edb2f0ca6dbe6d74bce9f967 215 Gene3D G3DSA:3.90.470.20 122 207 2.1E-11 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MED134_RS10150 cfd1d990edb2f0ca6dbe6d74bce9f967 215 Gene3D G3DSA:3.90.470.20 50 121 1.9E-9 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MED134_RS10150 cfd1d990edb2f0ca6dbe6d74bce9f967 215 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 111 190 2.5E-8 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MED134_RS10150 cfd1d990edb2f0ca6dbe6d74bce9f967 215 SUPERFAMILY SSF56214 111 191 2.88E-9 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MED134_RS10150 cfd1d990edb2f0ca6dbe6d74bce9f967 215 SUPERFAMILY SSF56214 37 104 2.09E-5 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MED134_RS07825 80b9639798e83ba3e75d4b13eecd1f03 118 PANTHER PTHR35145 1 118 5.8E-36 T 22-04-2016 MED134_RS07825 80b9639798e83ba3e75d4b13eecd1f03 118 Pfam PF04237 YjbR 12 102 1.2E-26 T 22-04-2016 IPR007351 Uncharacterised protein YjbR MED134_RS07825 80b9639798e83ba3e75d4b13eecd1f03 118 SUPERFAMILY SSF142906 1 116 6.67E-41 T 22-04-2016 MED134_RS09300 6f09c5a403648528099fc3bccb0dbca9 264 SUPERFAMILY SSF53448 11 234 8.84E-59 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS09300 6f09c5a403648528099fc3bccb0dbca9 264 PANTHER PTHR22916 4 262 6.4E-50 T 22-04-2016 MED134_RS09300 6f09c5a403648528099fc3bccb0dbca9 264 Gene3D G3DSA:3.90.550.10 11 237 9.3E-54 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS09300 6f09c5a403648528099fc3bccb0dbca9 264 Pfam PF00535 Glycosyl transferase family 2 14 154 1.6E-36 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS04350 e41863d158951df40338ed408d358b38 346 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 120 315 1.2E-19 T 22-04-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 MED134_RS04350 e41863d158951df40338ed408d358b38 346 SUPERFAMILY SSF53756 1 321 7.22E-32 T 22-04-2016 MED134_RS04355 da20b6d25caa3015cee377dec04b6885 174 Gene3D G3DSA:2.40.160.20 25 174 1.9E-4 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04355 da20b6d25caa3015cee377dec04b6885 174 SUPERFAMILY SSF56925 24 174 2.15E-9 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04355 da20b6d25caa3015cee377dec04b6885 174 Pfam PF13505 Outer membrane protein beta-barrel domain 6 174 1.2E-16 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel MED134_RS07345 4cc77e3c9d19f2d5c5a5064e2a26b10c 4766 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 4672 4762 2.4E-10 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS07345 4cc77e3c9d19f2d5c5a5064e2a26b10c 4766 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 278 345 3.7E-8 T 22-04-2016 IPR010221 VCBS repeat MED134_RS07345 4cc77e3c9d19f2d5c5a5064e2a26b10c 4766 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 597 666 7.9E-8 T 22-04-2016 IPR010221 VCBS repeat MED134_RS07345 4cc77e3c9d19f2d5c5a5064e2a26b10c 4766 Pfam PF13585 C-terminal domain of CHU protein family 4669 4755 7.4E-23 T 22-04-2016 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 242 258 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 396 414 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 372 390 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 272 291 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 56 81 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 461 478 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 147 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 147 166 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 437 452 5.68E-69 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PANTHER PTHR11686 4 563 6.3E-197 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 35 555 2.5E-161 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 PANTHER PTHR11686:SF9 4 563 6.3E-197 T 22-04-2016 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 Pfam PF01019 Gamma-glutamyltranspeptidase 49 557 1.9E-160 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MED134_RS01205 f73526b5c1ed7ce3c0850f906fa8046e 563 SUPERFAMILY SSF56235 29 563 6.95E-177 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS10575 cc93756add761967b758846ea6df9d23 226 PANTHER PTHR26402:SF472 4 115 3.0E-29 T 22-04-2016 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 Gene3D G3DSA:2.40.50.40 127 193 1.8E-18 T 22-04-2016 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 Gene3D G3DSA:3.40.50.2300 2 116 5.2E-28 T 22-04-2016 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 SMART SM00448 4 113 5.2E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 Pfam PF04397 LytTr DNA-binding domain 136 224 1.3E-17 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 SUPERFAMILY SSF52172 1 116 1.04E-25 T 22-04-2016 IPR011006 CheY-like superfamily MED134_RS10575 cc93756add761967b758846ea6df9d23 226 SMART SM00850 134 225 2.3E-18 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 PANTHER PTHR26402 4 115 3.0E-29 T 22-04-2016 MED134_RS10575 cc93756add761967b758846ea6df9d23 226 Pfam PF00072 Response regulator receiver domain 7 113 1.7E-20 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 MED134_RS13110 1c9d695aabb4d0fba0668eb172718726 438 SUPERFAMILY SSF111283 4 432 1.57E-89 T 22-04-2016 MED134_RS13110 1c9d695aabb4d0fba0668eb172718726 438 Pfam PF01523 Putative modulator of DNA gyrase 25 311 7.3E-46 T 22-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS13110 1c9d695aabb4d0fba0668eb172718726 438 PANTHER PTHR30624:SF8 1 436 6.5E-110 T 22-04-2016 MED134_RS13110 1c9d695aabb4d0fba0668eb172718726 438 PANTHER PTHR30624 1 436 6.5E-110 T 22-04-2016 MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 Gene3D G3DSA:1.20.1250.20 208 402 3.8E-23 T 22-04-2016 MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 Gene3D G3DSA:1.20.1250.20 8 192 9.1E-13 T 22-04-2016 MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 PANTHER PTHR23522:SF1 1 406 1.8E-137 T 22-04-2016 MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 SUPERFAMILY SSF103473 8 401 1.07E-38 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 Pfam PF03825 Nucleoside H+ symporter 5 401 5.4E-120 T 22-04-2016 MED134_RS09565 01bc2bc15d2d858db65922e77e98ec53 407 PANTHER PTHR23522 1 406 1.8E-137 T 22-04-2016 MED134_RS08785 73d55f3c90ce13189002facb5ef25ae3 158 TIGRFAM TIGR03511 GldH_lipo: gliding motility-associated lipoprotein GldH 6 156 2.4E-31 T 22-04-2016 IPR020018 Gliding motility-associated lipoprotein, GldH MED134_RS08785 73d55f3c90ce13189002facb5ef25ae3 158 Pfam PF14109 GldH lipoprotein 22 154 3.6E-38 T 22-04-2016 IPR020018 Gliding motility-associated lipoprotein, GldH MED134_RS11090 708ca47ae8cfbf2e4492c678096ad856 551 PANTHER PTHR33908 1 505 4.1E-36 T 22-04-2016 MED134_RS11090 708ca47ae8cfbf2e4492c678096ad856 551 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 61 233 8.1E-8 T 22-04-2016 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 MED134_RS13530 14f417f09132792d0f73eb87541a660c 579 Pfam PF07681 DoxX 6 93 2.6E-5 T 22-04-2016 IPR032808 DoxX family MED134_RS10850 ba9639a9632c30ef8da31ff12c93766a 141 SUPERFAMILY SSF82649 8 137 2.83E-44 T 22-04-2016 MED134_RS10850 ba9639a9632c30ef8da31ff12c93766a 141 Gene3D G3DSA:3.90.1010.10 3 139 1.7E-53 T 22-04-2016 MED134_RS10850 ba9639a9632c30ef8da31ff12c93766a 141 Pfam PF02657 Fe-S metabolism associated domain 13 130 8.9E-47 T 22-04-2016 IPR003808 Fe-S metabolism associated domain, SufE-like UniPathway: UPA00266 MED134_RS10850 ba9639a9632c30ef8da31ff12c93766a 141 PANTHER PTHR12735:SF11 2 138 1.1E-46 T 22-04-2016 MED134_RS10850 ba9639a9632c30ef8da31ff12c93766a 141 PANTHER PTHR12735 2 138 1.1E-46 T 22-04-2016 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 380 4.0E-122 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 Gene3D G3DSA:3.40.640.10 8 247 2.5E-78 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 Gene3D G3DSA:3.90.1150.10 248 382 3.6E-46 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 PANTHER PTHR11808 5 384 6.0E-157 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 SUPERFAMILY SSF53383 49 380 6.65E-103 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS03155 d1e56abc70f742ef7cda2313310c5d34 391 PIRSF PIRSF001434 1 382 3.7E-126 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS10430 f7f205df0f0a7cf990882afe09d48c4e 423 Pfam PF00924 Mechanosensitive ion channel 155 400 2.0E-38 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MED134_RS10430 f7f205df0f0a7cf990882afe09d48c4e 423 PANTHER PTHR30414 3 423 1.8E-130 T 22-04-2016 MED134_RS10430 f7f205df0f0a7cf990882afe09d48c4e 423 Gene3D G3DSA:2.30.30.60 210 260 8.9E-10 T 22-04-2016 MED134_RS10430 f7f205df0f0a7cf990882afe09d48c4e 423 PANTHER PTHR30414:SF0 3 423 1.8E-130 T 22-04-2016 IPR030192 Miniconductance mechanosensitive channel YbdG GO:0008381|GO:0016021|GO:0071470 MED134_RS10430 f7f205df0f0a7cf990882afe09d48c4e 423 SUPERFAMILY SSF50182 193 260 7.85E-11 T 22-04-2016 IPR010920 LSM domain MED134_RS09645 6d4c0b2f9ba2b79402f443797ec1328d 366 Gene3D G3DSA:2.20.28.30 14 39 5.1E-4 T 22-04-2016 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 MED134_RS09645 6d4c0b2f9ba2b79402f443797ec1328d 366 PANTHER PTHR37826:SF1 63 366 1.4E-52 T 22-04-2016 MED134_RS09645 6d4c0b2f9ba2b79402f443797ec1328d 366 PANTHER PTHR37826 63 366 1.4E-52 T 22-04-2016 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 SUPERFAMILY SSF88946 2 82 2.2E-15 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 160 5.2E-25 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 Pfam PF08281 Sigma-70, region 4 108 156 5.0E-14 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 Gene3D G3DSA:1.10.1740.10 2 78 3.0E-16 T 22-04-2016 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 SUPERFAMILY SSF88659 77 161 6.92E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 Gene3D G3DSA:1.10.10.10 101 160 5.2E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 PANTHER PTHR30173 2 160 7.0E-32 T 22-04-2016 MED134_RS14225 0afa6c532e6bd8388c53bcd449404590 169 Pfam PF04542 Sigma-70 region 2 9 75 1.8E-12 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 SUPERFAMILY SSF55729 8 150 1.68E-11 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 Gene3D G3DSA:3.40.630.30 9 191 2.4E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 SUPERFAMILY SSF56317 223 489 6.28E-59 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 Pfam PF00795 Carbon-nitrogen hydrolase 233 486 4.9E-34 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 Pfam PF00583 Acetyltransferase (GNAT) family 58 146 1.5E-5 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 Gene3D G3DSA:3.60.110.10 218 505 4.8E-60 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 PANTHER PTHR23088:SF12 209 508 1.0E-138 T 22-04-2016 MED134_RS01460 4e60fa26e7dc1b57fd08898b3547f1c1 508 PANTHER PTHR23088 209 508 1.0E-138 T 22-04-2016 MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 SUPERFAMILY SSF52833 1 211 1.14E-54 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 PIRSF PIRSF000239 1 213 4.0E-54 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 Pfam PF00578 AhpC/TSA family 4 153 1.1E-26 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 176 209 1.8E-7 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 PANTHER PTHR10681 3 212 6.9E-58 T 22-04-2016 MED134_RS04155 f762829df77b0a76148d0e3f05d7897d 214 Gene3D G3DSA:3.40.30.10 3 210 9.2E-58 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10070 b874ba9353558405ae1f1da0065a8b11 94 Pfam PF10985 Protein of unknown function (DUF2805) 10 82 3.3E-36 T 22-04-2016 IPR019882 Conserved hypothetical protein CHP03643 MED134_RS10070 b874ba9353558405ae1f1da0065a8b11 94 TIGRFAM TIGR03643 TIGR03643: TIGR03643 family protein 9 80 3.5E-34 T 22-04-2016 IPR019882 Conserved hypothetical protein CHP03643 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 PANTHER PTHR10885 1 166 6.7E-55 T 22-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 6 162 2.7E-40 T 22-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 PIRSF PIRSF018427 1 171 3.8E-53 T 22-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 Pfam PF00293 NUDIX domain 30 158 2.4E-19 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 4 170 31.098 T 22-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 Gene3D G3DSA:3.90.79.10 1 169 3.5E-53 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS00025 990d021e000dc5f90d333759a4886f5e 172 SUPERFAMILY SSF55811 4 168 5.55E-47 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 Gene3D G3DSA:3.40.50.720 1 153 2.9E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 Gene3D G3DSA:1.10.3730.10 156 259 2.2E-29 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 PANTHER PTHR11645 1 257 7.5E-83 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 261 21.648 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 259 2.5E-63 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 157 258 5.2E-27 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 SUPERFAMILY SSF48179 156 260 9.52E-28 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 93 7.8E-18 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 PIRSF PIRSF000193 1 262 2.0E-65 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 MED134_RS11750 1b17e7493aece3526f0201d0eb777a54 262 SUPERFAMILY SSF51735 1 154 7.86E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS04200 dd223746f473a2c417ee1307dc614871 353 Pfam PF05096 Glutamine cyclotransferase 106 350 1.6E-86 T 22-04-2016 IPR007788 Glutamine cyclotransferase MED134_RS04200 dd223746f473a2c417ee1307dc614871 353 SUPERFAMILY SSF50969 116 348 9.42E-18 T 22-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MED134_RS04200 dd223746f473a2c417ee1307dc614871 353 PANTHER PTHR31270 119 351 6.4E-83 T 22-04-2016 MED134_RS04200 dd223746f473a2c417ee1307dc614871 353 PANTHER PTHR31270:SF0 119 351 6.4E-83 T 22-04-2016 MED134_RS04200 dd223746f473a2c417ee1307dc614871 353 Gene3D G3DSA:2.130.10.10 145 349 4.4E-12 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS13165 4e35d41d28a0d9720df00405d672e87d 171 Pfam PF03929 PepSY-associated TM region 4 145 2.3E-8 T 22-04-2016 IPR005625 PepSY-associated TM protein MED134_RS13175 18d63c0b87257e73ea10c5088336f732 198 Gene3D G3DSA:3.40.50.1460 37 113 4.6E-4 T 22-04-2016 IPR029030 Caspase-like domain MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 3 188 3.5E-45 T 22-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 132 142 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 1 18 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 76 91 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 31 42 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 146 157 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PRINTS PR00988 Uridine kinase signature 168 181 4.6E-35 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 SUPERFAMILY SSF52540 3 194 3.75E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 Gene3D G3DSA:3.40.50.300 1 201 1.3E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 PANTHER PTHR10285 2 189 3.0E-83 T 22-04-2016 MED134_RS07670 24151b317df4873d9b8dc3fc7d819043 202 TIGRFAM TIGR00235 udk: uridine kinase 2 200 1.9E-80 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 Pfam PF00036 EF hand 24 48 1.3E-6 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 ProSitePatterns PS00018 EF-hand calcium-binding domain. 30 42 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 SUPERFAMILY SSF47473 4 84 1.15E-13 T 22-04-2016 IPR011992 EF-hand domain pair MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 SMART SM00054 21 49 0.011 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 SMART SM00054 59 87 23.0 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 MED134_RS01795 cd1a2f3b9b4a12efeb03222008f183ef 91 Gene3D G3DSA:1.10.238.10 17 83 8.6E-12 T 22-04-2016 IPR011992 EF-hand domain pair MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 Pfam PF00702 haloacid dehalogenase-like hydrolase 349 560 2.5E-32 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PANTHER PTHR24093:SF210 37 652 7.0E-239 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 103 650 8.5E-153 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 Pfam PF00122 E1-E2 ATPase 123 343 9.9E-56 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF56784 351 371 3.64E-51 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF56784 408 646 3.64E-51 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PANTHER PTHR24093 37 652 7.0E-239 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 Gene3D G3DSA:3.40.50.1000 471 617 1.4E-41 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 Gene3D G3DSA:3.40.1110.10 369 470 1.3E-9 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 125 626 3.0E-70 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF81653 154 251 9.94E-21 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 104 649 7.5E-162 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00941 Cadmium-transporting ATPase signature 156 172 7.3E-13 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00941 Cadmium-transporting ATPase signature 81 93 7.3E-13 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00941 Cadmium-transporting ATPase signature 136 156 7.3E-13 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00941 Cadmium-transporting ATPase signature 217 233 7.3E-13 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00941 Cadmium-transporting ATPase signature 236 250 7.3E-13 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 355 361 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 Gene3D G3DSA:2.70.150.10 102 252 5.4E-22 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF81665 252 347 2.35E-9 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF81665 102 155 2.35E-9 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 SUPERFAMILY SSF81665 596 637 2.35E-9 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 546 565 2.9E-17 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 570 582 2.9E-17 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 201 215 2.9E-17 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 492 502 2.9E-17 T 22-04-2016 MED134_RS00710 b536820a889472b6098ea4459ee07c35 655 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 353 367 2.9E-17 T 22-04-2016 MED134_RS08005 f23ad5e04eb1bb0ed0b33a24d59cd38d 381 Pfam PF00756 Putative esterase 28 173 4.4E-12 T 22-04-2016 IPR000801 Putative esterase MED134_RS08005 f23ad5e04eb1bb0ed0b33a24d59cd38d 381 SUPERFAMILY SSF53474 18 250 4.28E-31 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08005 f23ad5e04eb1bb0ed0b33a24d59cd38d 381 Gene3D G3DSA:3.40.50.1820 22 251 1.0E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS05910 2bdfdc69206af47411646032e89755c1 216 Gene3D G3DSA:2.30.110.10 18 193 7.2E-42 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS05910 2bdfdc69206af47411646032e89755c1 216 PANTHER PTHR33798 35 207 9.8E-20 T 22-04-2016 MED134_RS05910 2bdfdc69206af47411646032e89755c1 216 Pfam PF01613 Flavin reductase like domain 37 172 1.6E-14 T 22-04-2016 IPR002563 Flavin reductase like domain GO:0010181 MED134_RS05910 2bdfdc69206af47411646032e89755c1 216 SUPERFAMILY SSF50475 27 193 3.43E-30 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 MED134_RS09585 d2e24b698befc141417d8f740b8751b1 315 PANTHER PTHR12110 48 315 6.3E-40 T 22-04-2016 MED134_RS09585 d2e24b698befc141417d8f740b8751b1 315 Gene3D G3DSA:3.20.20.150 63 312 3.2E-66 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09585 d2e24b698befc141417d8f740b8751b1 315 Pfam PF01261 Xylose isomerase-like TIM barrel 72 260 9.2E-24 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09585 d2e24b698befc141417d8f740b8751b1 315 SUPERFAMILY SSF51658 55 293 5.47E-57 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain MED134_RS09585 d2e24b698befc141417d8f740b8751b1 315 PIRSF PIRSF006241 46 312 2.7E-89 T 22-04-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 MED134_RS02235 65dd36f9ad65ebbcdb77a4e1e44c9202 143 PANTHER PTHR36919 9 142 7.0E-26 T 22-04-2016 MED134_RS02235 65dd36f9ad65ebbcdb77a4e1e44c9202 143 PANTHER PTHR36919:SF1 9 142 7.0E-26 T 22-04-2016 MED134_RS02235 65dd36f9ad65ebbcdb77a4e1e44c9202 143 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 26 141 2.7E-30 T 22-04-2016 IPR019223 Domain of unknown function DUF2147 MED134_RS02560 eba2c2effa6ead7adfa8603942c78478 725 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 633 725 1.8E-35 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS02560 eba2c2effa6ead7adfa8603942c78478 725 Pfam PF13585 C-terminal domain of CHU protein family 634 707 4.5E-11 T 22-04-2016 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 PANTHER PTHR10629 1 408 7.2E-58 T 22-04-2016 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 112 124 - T 22-04-2016 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 SUPERFAMILY SSF53335 109 408 4.05E-81 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 SUPERFAMILY SSF53335 4 44 4.05E-81 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 6 405 1.0E-58 T 22-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 Pfam PF00145 C-5 cytosine-specific DNA methylase 5 406 1.7E-62 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 201 214 1.4E-14 T 22-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 155 169 1.4E-14 T 22-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 1.4E-14 T 22-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 Gene3D G3DSA:3.90.120.10 327 393 7.5E-10 T 22-04-2016 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 387 405 - T 22-04-2016 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 Gene3D G3DSA:3.40.50.150 1 44 2.4E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 Gene3D G3DSA:3.40.50.150 86 257 2.4E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS05690 2da3695a84511ba682a97b99f784a27c 409 PANTHER PTHR10629:SF32 1 408 7.2E-58 T 22-04-2016 MED134_RS02755 2efb1f824ae90e5ea232b06b85939539 477 PANTHER PTHR11819 2 424 6.6E-77 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS02755 2efb1f824ae90e5ea232b06b85939539 477 Pfam PF00474 Sodium:solute symporter family 33 406 5.2E-18 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS02755 2efb1f824ae90e5ea232b06b85939539 477 PANTHER PTHR11819:SF94 2 424 6.6E-77 T 22-04-2016 IPR031155 Urea active transporter GO:0015204|GO:0016021|GO:0071918 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 SUPERFAMILY SSF55874 215 340 6.02E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 SMART SM00388 128 196 8.9E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 SUPERFAMILY SSF47384 117 195 1.96E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 PANTHER PTHR24423 107 340 1.0E-56 T 22-04-2016 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 Gene3D G3DSA:3.30.565.10 202 340 1.8E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 194 2.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 321 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 300 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 286 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 340 3.1E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 342 2.1E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 Gene3D G3DSA:1.10.287.130 120 191 2.0E-8 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MED134_RS00610 cd6188f7eca21ce645681ddb5fc6bc90 343 SMART SM00387 234 343 3.0E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS14525 9fb477ebac70415c83b88a40e48cab7a 149 SMART SM00530 13 69 1.6E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS14525 9fb477ebac70415c83b88a40e48cab7a 149 Pfam PF01381 Helix-turn-helix 14 69 8.2E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS14525 9fb477ebac70415c83b88a40e48cab7a 149 Gene3D G3DSA:1.10.260.40 5 74 4.5E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS14525 9fb477ebac70415c83b88a40e48cab7a 149 SUPERFAMILY SSF47413 6 73 8.32E-10 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS00090 5e5f9c30387760d60bd11e284635b9e2 115 PANTHER PTHR36974 1 112 2.6E-21 T 22-04-2016 MED134_RS06215 7161ed751dc2c7d86ec27e59f46b834b 151 PANTHER PTHR21021:SF15 14 151 8.3E-36 T 22-04-2016 MED134_RS06215 7161ed751dc2c7d86ec27e59f46b834b 151 SUPERFAMILY SSF55781 16 149 7.63E-35 T 22-04-2016 IPR029016 GAF domain-like MED134_RS06215 7161ed751dc2c7d86ec27e59f46b834b 151 Pfam PF13185 GAF domain 25 148 2.0E-12 T 22-04-2016 IPR003018 GAF domain GO:0005515 MED134_RS06215 7161ed751dc2c7d86ec27e59f46b834b 151 PANTHER PTHR21021 14 151 8.3E-36 T 22-04-2016 MED134_RS06215 7161ed751dc2c7d86ec27e59f46b834b 151 Gene3D G3DSA:3.30.450.40 18 151 6.7E-35 T 22-04-2016 IPR029016 GAF domain-like MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 Pfam PF00106 short chain dehydrogenase 7 191 2.5E-53 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 Gene3D G3DSA:3.40.50.720 1 217 1.2E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 7.9E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.1E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.1E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.1E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.1E-25 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 SUPERFAMILY SSF51735 1 220 1.41E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 7.7E-4 T 22-04-2016 MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PANTHER PTHR24322 11 138 2.0E-47 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS01670 363aec9a088ee51188d661225fdfc732 238 PANTHER PTHR24322 154 185 2.0E-47 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 PANTHER PTHR12151:SF10 63 200 3.6E-28 T 22-04-2016 MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 Gene3D G3DSA:3.40.30.10 60 243 5.2E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 Gene3D G3DSA:3.40.30.10 7 19 5.2E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 PANTHER PTHR12151 63 200 3.6E-28 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 Pfam PF02630 SCO1/SenC 63 201 4.3E-21 T 22-04-2016 IPR003782 Copper chaperone SCO1/SenC MED134_RS11345 b75d4c2c795ea469a03a5c191c74b4ab 244 SUPERFAMILY SSF52833 62 211 1.48E-37 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 Pfam PF04055 Radical SAM superfamily 55 222 2.6E-12 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 PANTHER PTHR13932 4 446 4.4E-162 T 22-04-2016 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 SUPERFAMILY SSF102114 3 437 4.84E-115 T 22-04-2016 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 PANTHER PTHR13932:SF6 4 446 4.4E-162 T 22-04-2016 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 3 452 1.7E-129 T 22-04-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 Gene3D G3DSA:3.80.30.20 50 277 1.5E-26 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 SMART SM00729 50 272 1.8E-36 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MED134_RS04560 3b5a7b9b46f32a694528b50284bc6541 453 PIRSF PIRSF000167 2 449 2.2E-139 T 22-04-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 MED134_RS11645 16d39c7e71bcf3346947116c2daafec0 136 Pfam PF13715 CarboxypepD_reg-like domain 41 102 2.7E-11 T 22-04-2016 MED134_RS11645 16d39c7e71bcf3346947116c2daafec0 136 SUPERFAMILY SSF49464 39 104 2.75E-10 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS11645 16d39c7e71bcf3346947116c2daafec0 136 Gene3D G3DSA:2.60.40.1120 40 101 2.4E-6 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS10425 599e81d1e4455797a66ca1aa67cc1f15 367 Pfam PF14362 Domain of unknown function (DUF4407) 15 301 3.1E-99 T 22-04-2016 IPR025519 Protein of unknown function DUF4407 MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 Gene3D G3DSA:3.40.1190.20 3 304 4.2E-69 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 37 61 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 SUPERFAMILY SSF53613 4 305 1.87E-66 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 Pfam PF00294 pfkB family carbohydrate kinase 6 301 7.7E-49 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 PANTHER PTHR10584:SF161 1 301 5.5E-56 T 22-04-2016 MED134_RS11260 1eabb60e9d5b2d3fa33b7dc56973c215 317 PANTHER PTHR10584 1 301 5.5E-56 T 22-04-2016 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 SUPERFAMILY SSF51735 98 294 1.09E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 PANTHER PTHR10996:SF20 1 316 1.5E-93 T 22-04-2016 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 315 2.3E-26 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 Gene3D G3DSA:3.40.50.720 1 104 3.4E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 135 293 3.0E-46 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 Gene3D G3DSA:3.40.50.720 105 294 1.4E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 SUPERFAMILY SSF52283 1 118 1.23E-25 T 22-04-2016 MED134_RS02985 3ea2aa9ebd46f804bc8ed507995b33ea 316 PANTHER PTHR10996 1 316 1.5E-93 T 22-04-2016 MED134_RS05520 fba9b4f1fe4a6db7b94259a7b26197de 325 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 MED134_RS05520 fba9b4f1fe4a6db7b94259a7b26197de 325 SUPERFAMILY SSF48576 4 324 1.09E-80 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS05520 fba9b4f1fe4a6db7b94259a7b26197de 325 Gene3D G3DSA:1.10.600.10 5 325 2.2E-89 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS05520 fba9b4f1fe4a6db7b94259a7b26197de 325 Pfam PF00348 Polyprenyl synthetase 32 275 2.2E-63 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 MED134_RS05520 fba9b4f1fe4a6db7b94259a7b26197de 325 PANTHER PTHR12001 14 325 5.1E-83 T 22-04-2016 IPR017446 Polyprenyl synthetase-related MED134_RS07680 a078b307df307812ccc0955348158b1a 328 SUPERFAMILY SSF56219 19 322 7.98E-32 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS07680 a078b307df307812ccc0955348158b1a 328 Gene3D G3DSA:3.60.10.10 48 320 1.6E-13 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS07680 a078b307df307812ccc0955348158b1a 328 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 58 271 8.7E-10 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS04270 b22403625b51092c224815e2c8741c61 456 Gene3D G3DSA:3.40.50.1820 35 131 2.8E-6 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS04270 b22403625b51092c224815e2c8741c61 456 SUPERFAMILY SSF53474 37 153 2.35E-7 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS08090 4572b5ec2b1f03528da708c0ab1db5e9 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 190 3.5E-9 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08090 4572b5ec2b1f03528da708c0ab1db5e9 220 Gene3D G3DSA:3.40.50.1000 91 196 3.3E-12 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08090 4572b5ec2b1f03528da708c0ab1db5e9 220 Gene3D G3DSA:3.40.50.1000 7 24 3.3E-12 T 22-04-2016 IPR023214 HAD-like domain MED134_RS08090 4572b5ec2b1f03528da708c0ab1db5e9 220 SUPERFAMILY SSF56784 6 212 4.01E-24 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 PANTHER PTHR21485 6 169 1.3E-37 T 22-04-2016 MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 PANTHER PTHR21485:SF3 6 169 1.3E-37 T 22-04-2016 MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 15 163 1.0E-39 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 Pfam PF08282 haloacid dehalogenase-like hydrolase 84 149 1.1E-7 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 SUPERFAMILY SSF56784 10 166 1.08E-37 T 22-04-2016 IPR023214 HAD-like domain MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 PIRSF PIRSF006118 1 174 2.1E-54 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 MED134_RS00245 e0da54748c90d32f903ba81747b1e473 175 Gene3D G3DSA:3.40.50.1000 4 166 1.3E-39 T 22-04-2016 IPR023214 HAD-like domain MED134_RS06920 4f9b18ca90694de7c6c12b3bd49ec9f2 227 SUPERFAMILY SSF53335 18 220 3.09E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS06920 4f9b18ca90694de7c6c12b3bd49ec9f2 227 Gene3D G3DSA:3.40.50.150 6 225 6.3E-61 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS06920 4f9b18ca90694de7c6c12b3bd49ec9f2 227 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 150 225 1.9E-21 T 22-04-2016 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MED134_RS06920 4f9b18ca90694de7c6c12b3bd49ec9f2 227 PANTHER PTHR39963 3 226 1.1E-36 T 22-04-2016 MED134_RS04530 e090b6f46f2763c49b42e5ebf1c762c8 304 Pfam PF02517 CAAX protease self-immunity 139 234 9.9E-11 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 MED134_RS00215 1f649e544671d4bcccd09e782a015182 845 SUPERFAMILY SSF52317 636 815 3.66E-16 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS00215 1f649e544671d4bcccd09e782a015182 845 Gene3D G3DSA:2.60.40.10 524 586 4.8E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS00215 1f649e544671d4bcccd09e782a015182 845 Pfam PF02585 GlcNAc-PI de-N-acetylase 51 186 3.5E-13 T 22-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related MED134_RS00215 1f649e544671d4bcccd09e782a015182 845 SUPERFAMILY SSF102588 49 221 1.05E-26 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain MED134_RS00215 1f649e544671d4bcccd09e782a015182 845 Gene3D G3DSA:3.40.50.10320 49 301 7.6E-30 T 22-04-2016 IPR024078 Putative deacetylase LmbE-like domain MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 SUPERFAMILY SSF52540 1258 1409 1.34E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 1264 1385 8.7E-7 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 Pfam PF12458 ATPase involved in DNA repair 34 471 2.7E-188 T 22-04-2016 IPR020958 DUF3686 MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 SMART SM00382 1260 1409 2.2E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 Gene3D G3DSA:3.40.50.300 1106 1126 2.7E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05345 88b717ec02a57fa3685fec4143950506 1625 Gene3D G3DSA:3.40.50.300 1253 1394 2.7E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05550 2d87888697395bc6b63590c79083f131 490 SUPERFAMILY SSF47413 4 69 1.66E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS05550 2d87888697395bc6b63590c79083f131 490 Gene3D G3DSA:1.10.260.40 2 70 5.2E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS05550 2d87888697395bc6b63590c79083f131 490 SMART SM00530 13 68 4.7E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS05550 2d87888697395bc6b63590c79083f131 490 Pfam PF12844 Helix-turn-helix domain 13 66 2.0E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS10035 fd919c14628f5b3999afc985d749991b 86 Gene3D G3DSA:3.30.70.930 2 63 1.1E-7 T 22-04-2016 IPR029756 MTH1187/YkoF-like MED134_RS10035 fd919c14628f5b3999afc985d749991b 86 SUPERFAMILY SSF89957 1 76 2.62E-18 T 22-04-2016 IPR029756 MTH1187/YkoF-like MED134_RS13140 12ddb7904158b45f165e1749814d23cb 583 SUPERFAMILY SSF52317 233 421 2.75E-5 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS06640 535cd7c063823195cae2d2a06d63e2d1 336 SUPERFAMILY SSF51445 26 334 7.86E-50 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS06640 535cd7c063823195cae2d2a06d63e2d1 336 Gene3D G3DSA:3.20.20.80 165 320 5.8E-8 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS12610 560c50a2fe5a19540726a6e3e701e4b7 270 PANTHER PTHR30269:SF14 1 270 1.5E-42 T 22-04-2016 MED134_RS12610 560c50a2fe5a19540726a6e3e701e4b7 270 Pfam PF01925 Sulfite exporter TauE/SafE 10 260 1.5E-45 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 MED134_RS12610 560c50a2fe5a19540726a6e3e701e4b7 270 PANTHER PTHR30269 1 270 1.5E-42 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 MED134_RS07835 661e48fda69367e54a00c9f62ad823c0 206 Pfam PF14014 Protein of unknown function (DUF4230) 40 186 1.0E-28 T 22-04-2016 IPR025324 Protein of unknown function DUF4230 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 Pfam PF02569 Pantoate-beta-alanine ligase 4 279 5.0E-88 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 281 33.546 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 Gene3D G3DSA:3.30.1300.10 181 281 7.4E-21 T 22-04-2016 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 PANTHER PTHR21299 4 282 2.5E-93 T 22-04-2016 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 PANTHER PTHR21299:SF1 4 282 2.5E-93 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 SUPERFAMILY SSF52374 3 281 5.33E-90 T 22-04-2016 MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 Gene3D G3DSA:3.40.50.620 2 176 1.7E-61 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS07990 749f041f1d39f8c7f485435e075d4797 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 281 3.4E-78 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 MED134_RS05215 f7e8786208d012e327785d078cef971c 270 Gene3D G3DSA:1.25.40.10 26 244 5.6E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS05215 f7e8786208d012e327785d078cef971c 270 Pfam PF13525 Outer membrane lipoprotein 181 267 1.0E-7 T 22-04-2016 MED134_RS05215 f7e8786208d012e327785d078cef971c 270 Pfam PF13525 Outer membrane lipoprotein 28 175 6.5E-17 T 22-04-2016 MED134_RS05215 f7e8786208d012e327785d078cef971c 270 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 2 176 2.2E-28 T 22-04-2016 IPR017689 Outer membrane protein assembly factor BamD MED134_RS05215 f7e8786208d012e327785d078cef971c 270 SUPERFAMILY SSF48452 26 143 2.74E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 SMART SM00849 42 257 5.0E-11 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 PANTHER PTHR23200:SF41 1 285 5.0E-58 T 22-04-2016 MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 Pfam PF00753 Metallo-beta-lactamase superfamily 45 251 1.3E-14 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 SUPERFAMILY SSF56281 1 275 3.28E-37 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 PANTHER PTHR23200 1 285 5.0E-58 T 22-04-2016 MED134_RS09030 71dc2650b18741110e4d668f4133c7a3 286 Gene3D G3DSA:3.60.15.10 3 271 2.8E-41 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS10845 821c58854bb58c1a9d143ad46e805ebd 105 Pfam PF01883 Domain of unknown function DUF59 10 83 1.3E-19 T 22-04-2016 IPR002744 Domain of unknown function DUF59 MED134_RS10845 821c58854bb58c1a9d143ad46e805ebd 105 PANTHER PTHR13696:SF62 1 102 1.8E-19 T 22-04-2016 MED134_RS10845 821c58854bb58c1a9d143ad46e805ebd 105 PANTHER PTHR13696 1 102 1.8E-19 T 22-04-2016 MED134_RS10845 821c58854bb58c1a9d143ad46e805ebd 105 SUPERFAMILY SSF117916 10 104 6.21E-31 T 22-04-2016 MED134_RS11795 0042406424962b3b893aba702482296d 204 PANTHER PTHR11670:SF27 1 204 3.4E-85 T 22-04-2016 MED134_RS11795 0042406424962b3b893aba702482296d 204 Gene3D G3DSA:3.20.19.10 2 202 7.4E-41 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MED134_RS11795 0042406424962b3b893aba702482296d 204 PANTHER PTHR11670 1 204 3.4E-85 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11795 0042406424962b3b893aba702482296d 204 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 204 37.764 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11795 0042406424962b3b893aba702482296d 204 SUPERFAMILY SSF52016 1 198 1.45E-52 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MED134_RS11795 0042406424962b3b893aba702482296d 204 Pfam PF00694 Aconitase C-terminal domain 1 122 2.7E-32 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS11795 0042406424962b3b893aba702482296d 204 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 194 4.3E-62 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 MED134_RS02945 d31982d9a917dd1e6c6fa916d8df9751 402 SUPERFAMILY SSF103473 17 401 1.57E-55 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS02945 d31982d9a917dd1e6c6fa916d8df9751 402 Pfam PF07690 Major Facilitator Superfamily 33 359 1.6E-42 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MED134_RS02945 d31982d9a917dd1e6c6fa916d8df9751 402 PANTHER PTHR23517 1 398 3.0E-48 T 22-04-2016 MED134_RS02945 d31982d9a917dd1e6c6fa916d8df9751 402 Gene3D G3DSA:1.20.1250.20 20 202 3.4E-30 T 22-04-2016 MED134_RS02945 d31982d9a917dd1e6c6fa916d8df9751 402 Gene3D G3DSA:1.20.1250.20 203 396 7.8E-20 T 22-04-2016 MED134_RS10570 263800cda5c0d498ad67a2014d33af79 337 PANTHER PTHR34220 108 336 1.7E-60 T 22-04-2016 MED134_RS10570 263800cda5c0d498ad67a2014d33af79 337 Pfam PF06580 Histidine kinase 149 225 2.7E-23 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MED134_RS10570 263800cda5c0d498ad67a2014d33af79 337 PANTHER PTHR34220:SF1 108 336 1.7E-60 T 22-04-2016 MED134_RS01855 53c76c137c993a75f8d5466d84a0bf8c 135 SUPERFAMILY SSF54909 33 131 3.33E-20 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS01855 53c76c137c993a75f8d5466d84a0bf8c 135 Gene3D G3DSA:3.30.70.900 23 132 1.8E-35 T 22-04-2016 MED134_RS01855 53c76c137c993a75f8d5466d84a0bf8c 135 SMART SM00886 36 134 4.6E-10 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel MED134_RS01855 53c76c137c993a75f8d5466d84a0bf8c 135 Pfam PF07876 Stress responsive A/B Barrel Domain 38 132 1.1E-11 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel MED134_RS02190 63b2906c5377d0f2ca61bc6fb00c4159 222 Pfam PF03006 Haemolysin-III related 13 206 5.1E-40 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MED134_RS02190 63b2906c5377d0f2ca61bc6fb00c4159 222 PANTHER PTHR20855:SF3 11 213 1.1E-64 T 22-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 MED134_RS02190 63b2906c5377d0f2ca61bc6fb00c4159 222 PANTHER PTHR20855 11 213 1.1E-64 T 22-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MED134_RS02190 63b2906c5377d0f2ca61bc6fb00c4159 222 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 213 1.5E-65 T 22-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 PANTHER PTHR11717 1 139 3.1E-44 T 22-04-2016 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 Gene3D G3DSA:3.40.50.270 1 144 1.2E-46 T 22-04-2016 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 SMART SM00226 2 143 1.2E-40 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 SUPERFAMILY SSF52788 1 144 6.8E-43 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 2 139 2.0E-37 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 72 87 1.1E-14 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 38 54 1.1E-14 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 1.1E-14 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MED134_RS13690 fcf135501ccce0250df881657da23ee6 145 PANTHER PTHR11717:SF7 1 139 3.1E-44 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MED134_RS03985 d8517a9f2e92ab36328222638fa281d9 347 PANTHER PTHR30518 1 347 3.0E-63 T 22-04-2016 MED134_RS03985 d8517a9f2e92ab36328222638fa281d9 347 Gene3D G3DSA:3.30.160.60 306 344 1.8E-10 T 22-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 MED134_RS03985 d8517a9f2e92ab36328222638fa281d9 347 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 4 342 1.2E-56 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like MED134_RS03985 d8517a9f2e92ab36328222638fa281d9 347 Pfam PF02618 YceG-like family 44 333 4.8E-69 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like MED134_RS03985 d8517a9f2e92ab36328222638fa281d9 347 PANTHER PTHR30518:SF2 1 347 3.0E-63 T 22-04-2016 MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 Gene3D G3DSA:3.10.129.10 8 132 4.2E-35 T 22-04-2016 IPR029069 HotDog domain MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 PANTHER PTHR12418 1 131 7.3E-30 T 22-04-2016 MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 Pfam PF03061 Thioesterase superfamily 46 119 2.0E-10 T 22-04-2016 IPR006683 Thioesterase domain MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 127 1.6E-21 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 PANTHER PTHR12418:SF24 1 131 7.3E-30 T 22-04-2016 MED134_RS11520 833ad7e9bfe2867eab8d0c90423bcc2d 136 SUPERFAMILY SSF54637 8 128 7.11E-25 T 22-04-2016 IPR029069 HotDog domain MED134_RS10200 0eebd63ff00c6ca7733e6bc6c388508d 187 TIGRFAM TIGR03512 GldD_lipo: gliding motility-associated lipoprotein GldD 7 186 1.2E-67 T 22-04-2016 IPR019850 Gliding motility-associated lipoprotein, GldD MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 Gene3D G3DSA:3.40.640.10 65 275 9.5E-73 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 Pfam PF00155 Aminotransferase class I and II 27 389 4.3E-41 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 SUPERFAMILY SSF53383 21 392 3.82E-79 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 Gene3D G3DSA:3.90.1150.10 276 388 7.5E-17 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 PANTHER PTHR13693 27 392 7.5E-132 T 22-04-2016 MED134_RS07940 f446b6967148c37cf90eaebd167f8b0a 394 PANTHER PTHR13693:SF53 27 392 7.5E-132 T 22-04-2016 MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 Gene3D G3DSA:2.160.10.10 147 253 1.9E-27 T 22-04-2016 MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 Gene3D G3DSA:1.10.3130.10 63 146 4.6E-27 T 22-04-2016 MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 206 240 4.6E-4 T 22-04-2016 IPR001451 Hexapeptide repeat MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 SUPERFAMILY SSF51161 66 254 2.91E-39 T 22-04-2016 IPR011004 Trimeric LpxA-like MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 PANTHER PTHR23416:SF65 78 250 6.4E-68 T 22-04-2016 MED134_RS12630 ebc2335d399a5be3949ea8e09f2ed96d 266 PANTHER PTHR23416 78 250 6.4E-68 T 22-04-2016 MED134_RS00690 a1626910048e35203eaba497b8ee290e 205 Pfam PF01914 MarC family integral membrane protein 7 200 1.5E-49 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS00690 a1626910048e35203eaba497b8ee290e 205 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 198 9.1E-48 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MED134_RS00690 a1626910048e35203eaba497b8ee290e 205 PANTHER PTHR33508:SF1 1 199 8.0E-60 T 22-04-2016 MED134_RS00690 a1626910048e35203eaba497b8ee290e 205 PANTHER PTHR33508 1 199 8.0E-60 T 22-04-2016 MED134_RS10140 5dde5356bc390c879b7ce59995971776 86 SMART SM00679 17 48 4.5E-5 T 22-04-2016 IPR006603 PQ-loop repeat MED134_RS10140 5dde5356bc390c879b7ce59995971776 86 Pfam PF04193 PQ loop repeat 5 59 2.2E-15 T 22-04-2016 IPR006603 PQ-loop repeat MED134_RS10795 4074e99cce7ec0ab055eb0f8b2597fe1 80 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 76 3.0E-8 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MED134_RS10795 4074e99cce7ec0ab055eb0f8b2597fe1 80 PANTHER PTHR11178 10 78 2.2E-19 T 22-04-2016 MED134_RS10795 4074e99cce7ec0ab055eb0f8b2597fe1 80 SUPERFAMILY SSF117916 2 78 3.05E-24 T 22-04-2016 MED134_RS10795 4074e99cce7ec0ab055eb0f8b2597fe1 80 Pfam PF01106 NifU-like domain 10 76 6.7E-27 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MED134_RS13600 4c18172651ca0e2d5a5b1aa8c1e0b60d 427 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 57 201 2.7E-6 T 22-04-2016 MED134_RS09015 44b9d71de5d4defd7f1de2e00d5c6a9a 166 Pfam PF00583 Acetyltransferase (GNAT) family 55 144 2.0E-17 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS09015 44b9d71de5d4defd7f1de2e00d5c6a9a 166 Gene3D G3DSA:3.40.630.30 2 165 8.2E-47 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09015 44b9d71de5d4defd7f1de2e00d5c6a9a 166 SUPERFAMILY SSF55729 2 155 3.26E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS09015 44b9d71de5d4defd7f1de2e00d5c6a9a 166 PANTHER PTHR23091 1 147 5.1E-20 T 22-04-2016 MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 PANTHER PTHR11751 6 380 3.8E-123 T 22-04-2016 MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 Gene3D G3DSA:3.40.640.10 41 268 7.0E-75 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 PANTHER PTHR11751:SF301 6 380 3.8E-123 T 22-04-2016 MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 SUPERFAMILY SSF53383 2 379 4.26E-96 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 Pfam PF00155 Aminotransferase class I and II 28 375 8.0E-57 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MED134_RS08105 c969c0b9b73a55f0855ff526588f9a21 380 Gene3D G3DSA:3.90.1150.10 269 377 6.3E-18 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 SUPERFAMILY SSF52402 1 154 1.84E-27 T 22-04-2016 MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 PANTHER PTHR31964:SF26 1 160 8.9E-20 T 22-04-2016 MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 SUPERFAMILY SSF52402 152 274 3.43E-8 T 22-04-2016 MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 PRINTS PR01438 Universal stress protein signature 120 142 2.8E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 PRINTS PR01438 Universal stress protein signature 1 19 2.8E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 PRINTS PR01438 Universal stress protein signature 102 114 2.8E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 PANTHER PTHR31964 1 160 8.9E-20 T 22-04-2016 MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 Gene3D G3DSA:3.40.50.620 1 144 1.1E-26 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS00700 9fc3316d9975e40c5f6885815e9f05e4 278 Pfam PF00582 Universal stress protein family 2 143 2.8E-20 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS09220 12748fbfbc7f1ceaf28f8ea84ce83261 288 Pfam PF01551 Peptidase family M23 186 281 1.1E-28 T 22-04-2016 IPR016047 Peptidase M23 MED134_RS09220 12748fbfbc7f1ceaf28f8ea84ce83261 288 SUPERFAMILY SSF51261 76 285 1.83E-44 T 22-04-2016 IPR011055 Duplicated hybrid motif MED134_RS09220 12748fbfbc7f1ceaf28f8ea84ce83261 288 Gene3D G3DSA:2.70.70.10 151 286 3.3E-38 T 22-04-2016 MED134_RS09220 12748fbfbc7f1ceaf28f8ea84ce83261 288 PANTHER PTHR21666 92 286 1.5E-36 T 22-04-2016 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PANTHER PTHR23403 345 618 3.4E-237 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PANTHER PTHR23403 6 326 3.4E-237 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 SUPERFAMILY SSF48208 94 596 3.06E-108 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 ProSitePatterns PS00928 Trehalase signature 2. 504 513 - T 22-04-2016 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 Pfam PF01204 Trehalase 89 600 2.0E-135 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 Pfam PF07492 Neutral trehalase Ca2+ binding domain 11 37 1.2E-12 T 22-04-2016 IPR011120 Neutral trehalase Ca2+ binding GO:0004555|GO:0005509|GO:0005737|GO:0005993 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PANTHER PTHR23403:SF6 345 618 3.4E-237 T 22-04-2016 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PANTHER PTHR23403:SF6 6 326 3.4E-237 T 22-04-2016 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 583 596 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 377 394 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 353 370 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 424 440 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 497 513 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 298 315 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 PRINTS PR00744 Glycosyl hydrolase family 37 signature 233 251 9.0E-42 T 22-04-2016 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS11255 abb7f5a14e5df94696b58270954d2cc4 618 ProSitePatterns PS00927 Trehalase signature 1. 191 204 - T 22-04-2016 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28 MED134_RS04295 b956894748e32b9670644a159cab57fc 536 SUPERFAMILY SSF53335 280 396 1.96E-12 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS04295 b956894748e32b9670644a159cab57fc 536 Gene3D G3DSA:3.40.50.150 302 398 7.9E-11 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS08270 c3b124a9270ed3afa4411600f29c9fab 102 Pfam PF14114 Domain of unknown function (DUF4286) 3 98 2.5E-34 T 22-04-2016 IPR025563 Protein of unknown function DUF4286 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 2 136 18.121 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 SUPERFAMILY SSF53098 2 134 1.26E-32 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 Gene3D G3DSA:3.30.420.140 2 134 1.2E-36 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 PANTHER PTHR33317 3 133 6.3E-27 T 22-04-2016 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 6 133 2.4E-20 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 Pfam PF03652 Holliday junction resolvase 3 133 4.8E-34 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MED134_RS04325 42581972a086a0c99e7ce98a720bab6b 136 SMART SM00732 2 100 5.8E-16 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 MED134_RS13385 96dbbdac76ff26598282c2312f5ab789 259 SUPERFAMILY SSF53448 2 232 5.06E-30 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13385 96dbbdac76ff26598282c2312f5ab789 259 Pfam PF00535 Glycosyl transferase family 2 3 124 2.5E-8 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS13385 96dbbdac76ff26598282c2312f5ab789 259 Gene3D G3DSA:3.90.550.10 2 207 2.4E-14 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417 188 409 2.7E-46 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417 129 139 2.7E-46 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417 1 110 2.7E-46 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 48 207 2.6E-43 T 22-04-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675|UniPathway: UPA00958 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 SUPERFAMILY SSF53756 54 397 4.71E-5 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417:SF2 188 409 2.7E-46 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417:SF2 129 139 2.7E-46 T 22-04-2016 MED134_RS07300 bdfa4eb6c4ab4b35b1d21ac03bb44775 412 PANTHER PTHR23417:SF2 1 110 2.7E-46 T 22-04-2016 MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 SUPERFAMILY SSF52540 3 78 6.39E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 SUPERFAMILY SSF52540 107 286 6.39E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 PANTHER PTHR30473 1 318 1.7E-131 T 22-04-2016 MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 Gene3D G3DSA:3.40.50.300 108 310 6.2E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 Pfam PF02562 PhoH-like protein 108 310 9.8E-91 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 MED134_RS04830 65f6f7f29f0cca1603127fb257976ade 318 PANTHER PTHR30473:SF1 1 318 1.7E-131 T 22-04-2016 MED134_RS13225 af7dd08c058be275bd7edccc9addb9af 298 Gene3D G3DSA:2.40.160.60 89 159 2.9E-4 T 22-04-2016 MED134_RS13225 af7dd08c058be275bd7edccc9addb9af 298 SUPERFAMILY SSF56935 36 159 7.66E-6 T 22-04-2016 MED134_RS14220 fd00306794c521af424737e1305a6902 628 Pfam PF14849 YidC periplasmic domain 96 367 1.1E-31 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal MED134_RS14220 fd00306794c521af424737e1305a6902 628 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 381 582 4.3E-56 T 22-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal MED134_RS14220 fd00306794c521af424737e1305a6902 628 PRINTS PR00701 60kDa inner membrane protein signature 441 464 8.0E-10 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 PRINTS PR00701 60kDa inner membrane protein signature 101 122 8.0E-10 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 PRINTS PR00701 60kDa inner membrane protein signature 266 281 8.0E-10 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 Pfam PF02096 60Kd inner membrane protein 381 583 3.8E-54 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 PANTHER PTHR12428:SF14 370 625 2.9E-55 T 22-04-2016 MED134_RS14220 fd00306794c521af424737e1305a6902 628 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 7 586 14.015 T 22-04-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 PANTHER PTHR12428 370 625 2.9E-55 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MED134_RS14220 fd00306794c521af424737e1305a6902 628 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 8 366 1.5E-24 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 PANTHER PTHR30349 3 296 3.7E-75 T 22-04-2016 MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 Gene3D G3DSA:1.10.150.130 3 94 6.5E-22 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 Pfam PF00589 Phage integrase family 113 279 3.5E-36 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 294 27.624 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 PANTHER PTHR30349:SF5 3 296 3.7E-75 T 22-04-2016 MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 SUPERFAMILY SSF56349 10 286 4.71E-47 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 4 85 1.2E-16 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MED134_RS04955 9e0d0241707e932dfcb4fd2a417af778 296 Gene3D G3DSA:1.10.443.10 109 287 2.0E-46 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MED134_RS03085 e9bb2a07f12b795c70935b66aa6dea30 172 Pfam PF09413 Putative prokaryotic signal transducing protein 12 73 5.4E-9 T 22-04-2016 IPR018551 Domain of unknown function DUF2007 MED134_RS14115 e4f39e70ae510d90da2305880ab7a311 351 Pfam PF04245 37-kD nucleoid-associated bacterial protein 14 339 1.3E-57 T 22-04-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 Gene3D G3DSA:3.40.1400.10 1 141 2.1E-59 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 PIRSF PIRSF005384 1 142 6.6E-54 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 141 9.2E-48 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 141 1.9E-42 T 22-04-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 PANTHER PTHR30345 1 141 3.6E-64 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 Pfam PF02502 Ribose/Galactose Isomerase 3 140 9.4E-56 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS09085 7c2d4cc78512b7090e62d5230abc729e 143 SUPERFAMILY SSF89623 1 141 2.62E-54 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 PANTHER PTHR10668:SF4 5 486 2.4E-89 T 22-04-2016 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 PANTHER PTHR10668 5 486 2.4E-89 T 22-04-2016 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 SUPERFAMILY SSF51905 443 483 7.77E-64 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 SUPERFAMILY SSF51905 1 314 7.77E-64 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 Gene3D G3DSA:3.50.50.60 2 94 5.5E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 Gene3D G3DSA:3.50.50.60 199 345 5.5E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 Pfam PF01593 Flavin containing amine oxidoreductase 15 481 2.2E-30 T 22-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 MED134_RS12885 1aa97abbf1a32c71dad230a9dab3749e 486 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 483 3.5E-116 T 22-04-2016 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 MED134_RS01025 bd7dfc645909c9db44de2582c46f03fa 253 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 75 97 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MED134_RS01025 bd7dfc645909c9db44de2582c46f03fa 253 Pfam PF01066 CDP-alcohol phosphatidyltransferase 34 97 1.3E-9 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MED134_RS00535 a62b1dfce16eadcb1e960bc5b9e5d700 321 PANTHER PTHR24014:SF4 62 270 1.2E-21 T 22-04-2016 MED134_RS00535 a62b1dfce16eadcb1e960bc5b9e5d700 321 PANTHER PTHR24014 62 270 1.2E-21 T 22-04-2016 MED134_RS00535 a62b1dfce16eadcb1e960bc5b9e5d700 321 SUPERFAMILY SSF51197 100 276 4.26E-10 T 22-04-2016 MED134_RS12980 86f0018f266677882677c4b842fd4060 160 SUPERFAMILY SSF50242 33 156 9.81E-13 T 22-04-2016 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold MED134_RS12980 86f0018f266677882677c4b842fd4060 160 Pfam PF00965 Tissue inhibitor of metalloproteinase 36 114 7.7E-5 T 22-04-2016 IPR001820 Protease inhibitor I35 (TIMP) GO:0008191 MED134_RS12980 86f0018f266677882677c4b842fd4060 160 Gene3D G3DSA:2.40.50.120 32 153 2.4E-6 T 22-04-2016 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 Gene3D G3DSA:3.90.1150.10 322 425 6.1E-40 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 Gene3D G3DSA:3.90.1150.10 4 71 6.1E-40 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 Pfam PF00202 Aminotransferase class-III 35 412 1.7E-82 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 Gene3D G3DSA:3.40.640.10 73 317 2.2E-81 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 99.757 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 SUPERFAMILY SSF53383 4 426 1.55E-126 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 1.8E-181 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 PANTHER PTHR11986:SF5 1 428 4.7E-203 T 22-04-2016 MED134_RS11600 1253a7303ea9cf06613e0918f92cccf3 428 PANTHER PTHR11986 1 428 4.7E-203 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MED134_RS07875 881cc4e7c59709bc45199d8cd0ab4b24 480 Pfam PF00939 Sodium:sulfate symporter transmembrane region 20 472 9.1E-83 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS07875 881cc4e7c59709bc45199d8cd0ab4b24 480 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 426 442 - T 22-04-2016 IPR031312 Sodium/sulphate symporter, conserved site MED134_RS07875 881cc4e7c59709bc45199d8cd0ab4b24 480 PANTHER PTHR10283:SF82 1 480 5.5E-139 T 22-04-2016 MED134_RS07875 881cc4e7c59709bc45199d8cd0ab4b24 480 PANTHER PTHR10283 1 480 5.5E-139 T 22-04-2016 MED134_RS07875 881cc4e7c59709bc45199d8cd0ab4b24 480 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 34 471 2.4E-89 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS09775 a6772ab45fdaa5433d58cd75c455e942 118 Gene3D G3DSA:3.40.30.10 3 110 7.6E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS09775 a6772ab45fdaa5433d58cd75c455e942 118 SUPERFAMILY SSF52833 3 110 3.06E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS09775 a6772ab45fdaa5433d58cd75c455e942 118 Pfam PF03960 ArsC family 33 108 1.3E-9 T 22-04-2016 IPR006660 Arsenate reductase-like MED134_RS00680 5082c038375d514ec472738b72792c86 269 SUPERFAMILY SSF53448 1 199 4.5E-29 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS00680 5082c038375d514ec472738b72792c86 269 PANTHER PTHR10859 5 243 1.2E-42 T 22-04-2016 MED134_RS00680 5082c038375d514ec472738b72792c86 269 Gene3D G3DSA:3.90.550.10 2 196 5.8E-22 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS00680 5082c038375d514ec472738b72792c86 269 Pfam PF00535 Glycosyl transferase family 2 5 168 8.4E-19 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS00400 798b08232445cbb61ededa713c186c4b 337 PANTHER PTHR34580:SF3 1 337 4.0E-35 T 22-04-2016 MED134_RS00400 798b08232445cbb61ededa713c186c4b 337 PANTHER PTHR34580 1 337 4.0E-35 T 22-04-2016 MED134_RS00400 798b08232445cbb61ededa713c186c4b 337 Pfam PF13280 WYL domain 159 333 1.4E-29 T 22-04-2016 IPR026881 WYL domain MED134_RS00475 d4694272977389cc4e89d87a583f3f21 389 PANTHER PTHR34985 51 334 1.2E-18 T 22-04-2016 MED134_RS00475 d4694272977389cc4e89d87a583f3f21 389 Pfam PF05272 Virulence-associated protein E 96 284 1.7E-20 T 22-04-2016 IPR007936 Virulence-associated E MED134_RS02920 c630fee2afb5a74e25759b557c273be0 138 PANTHER PTHR39434:SF1 1 138 1.7E-43 T 22-04-2016 MED134_RS02920 c630fee2afb5a74e25759b557c273be0 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 1.3E-6 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS02920 c630fee2afb5a74e25759b557c273be0 138 Gene3D G3DSA:3.10.180.10 6 135 3.8E-23 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS02920 c630fee2afb5a74e25759b557c273be0 138 PANTHER PTHR39434 1 138 1.7E-43 T 22-04-2016 MED134_RS02920 c630fee2afb5a74e25759b557c273be0 138 SUPERFAMILY SSF54593 1 131 2.26E-21 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS11625 ae18d3f2186d4dafe902d8d1fe5225ea 128 Pfam PF04134 Protein of unknown function, DUF393 10 118 4.5E-26 T 22-04-2016 IPR007263 Protein of unknown function DUF393 MED134_RS11625 ae18d3f2186d4dafe902d8d1fe5225ea 128 PANTHER PTHR33639 9 125 5.7E-34 T 22-04-2016 MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 Pfam PF01523 Putative modulator of DNA gyrase 61 386 3.4E-57 T 22-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 PANTHER PTHR30624 35 246 9.4E-200 T 22-04-2016 MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 PANTHER PTHR30624 265 542 9.4E-200 T 22-04-2016 MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 PANTHER PTHR30624:SF10 35 246 9.4E-200 T 22-04-2016 MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 PANTHER PTHR30624:SF10 265 542 9.4E-200 T 22-04-2016 MED134_RS13105 b4bf20e655c0bb87b6794af0d7dbf12d 544 SUPERFAMILY SSF111283 42 538 4.19E-94 T 22-04-2016 MED134_RS12600 5e37b64909f25528b980d7dfae2f7784 104 Gene3D G3DSA:3.40.250.10 1 100 2.4E-22 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12600 5e37b64909f25528b980d7dfae2f7784 104 Pfam PF00581 Rhodanese-like domain 10 98 8.8E-9 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12600 5e37b64909f25528b980d7dfae2f7784 104 SMART SM00450 5 103 1.5E-11 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS12600 5e37b64909f25528b980d7dfae2f7784 104 SUPERFAMILY SSF52821 2 100 2.88E-23 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS14370 13ac88eb761c6192b4042c039382a563 800 SUPERFAMILY SSF49344 23 219 7.06E-36 T 22-04-2016 MED134_RS14370 13ac88eb761c6192b4042c039382a563 800 Gene3D G3DSA:2.60.40.1190 23 211 7.3E-31 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS14370 13ac88eb761c6192b4042c039382a563 800 Pfam PF06452 Carbohydrate family 9 binding domain-like 33 189 6.4E-8 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS12865 c19f8bbd5677bf91acf85c9521bc84bd 338 Pfam PF00535 Glycosyl transferase family 2 9 177 8.4E-24 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS12865 c19f8bbd5677bf91acf85c9521bc84bd 338 Gene3D G3DSA:3.90.550.10 6 240 5.7E-43 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS12865 c19f8bbd5677bf91acf85c9521bc84bd 338 Gene3D G3DSA:3.40.50.720 244 337 2.1E-4 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12865 c19f8bbd5677bf91acf85c9521bc84bd 338 SUPERFAMILY SSF53448 6 232 5.53E-45 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS12865 c19f8bbd5677bf91acf85c9521bc84bd 338 PANTHER PTHR22916 4 244 3.7E-40 T 22-04-2016 MED134_RS14070 deb8d7fe142cd6c64c8a5605057c93e4 169 SUPERFAMILY SSF55961 4 150 1.88E-21 T 22-04-2016 MED134_RS02420 9ce4bb1e832cfd447461f99309feafda 171 Pfam PF07609 Protein of unknown function (DUF1572) 8 153 6.7E-12 T 22-04-2016 IPR011466 Protein of unknown function DUF1572 MED134_RS02420 9ce4bb1e832cfd447461f99309feafda 171 SUPERFAMILY SSF109854 8 150 3.11E-18 T 22-04-2016 MED134_RS02420 9ce4bb1e832cfd447461f99309feafda 171 Gene3D G3DSA:1.20.120.450 29 146 3.1E-15 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 317 333 4.0E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 302 317 4.0E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 PANTHER PTHR11019 232 334 2.6E-21 T 22-04-2016 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 SMART SM00342 249 333 3.8E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 SUPERFAMILY SSF46689 286 334 1.03E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 Gene3D G3DSA:1.10.10.60 234 286 1.8E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 Pfam PF12833 Helix-turn-helix domain 256 334 1.5E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 SUPERFAMILY SSF46689 235 284 3.72E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS04845 8bf0696291e264a72bfff55e24143da0 338 Gene3D G3DSA:1.10.10.60 287 334 2.5E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 PANTHER PTHR33164 1 147 4.7E-22 T 22-04-2016 MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 SMART SM00347 23 122 1.1E-15 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 SUPERFAMILY SSF46785 6 140 1.21E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 22-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 Pfam PF01047 MarR family 36 88 2.5E-11 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MED134_RS01155 815af34799f2adda398b3061c4c9ce2c 151 Gene3D G3DSA:1.10.10.10 5 139 1.1E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS08695 b5a39ec510c808609b6ebd4904faa61a 252 PANTHER PTHR37468 1 235 2.8E-22 T 22-04-2016 MED134_RS08695 b5a39ec510c808609b6ebd4904faa61a 252 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 15 224 2.0E-28 T 22-04-2016 MED134_RS08645 a8320277d848855bd779aac91d522508 460 PANTHER PTHR11206 3 449 7.7E-114 T 22-04-2016 MED134_RS08645 a8320277d848855bd779aac91d522508 460 PIRSF PIRSF006603 1 460 8.2E-79 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS08645 a8320277d848855bd779aac91d522508 460 Pfam PF01554 MatE 24 185 1.4E-27 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS08645 a8320277d848855bd779aac91d522508 460 Pfam PF01554 MatE 253 411 5.0E-15 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS08645 a8320277d848855bd779aac91d522508 460 PANTHER PTHR11206:SF132 3 449 7.7E-114 T 22-04-2016 MED134_RS08645 a8320277d848855bd779aac91d522508 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 420 3.3E-45 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 Pfam PF13620 Carboxypeptidase regulatory-like domain 33 109 9.1E-9 T 22-04-2016 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 Gene3D G3DSA:2.60.40.1120 33 110 1.9E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 SUPERFAMILY SSF49452 28 109 5.49E-12 T 22-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 Gene3D G3DSA:2.120.10.60 365 475 6.4E-17 T 22-04-2016 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 Gene3D G3DSA:2.120.10.60 212 323 6.4E-17 T 22-04-2016 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 SUPERFAMILY SSF49265 116 213 2.61E-5 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS03795 7a19781cd288095e43a2dda2ed65705d 501 SUPERFAMILY SSF69304 214 481 3.01E-13 T 22-04-2016 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 PANTHER PTHR10366:SF401 2 238 1.3E-75 T 22-04-2016 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 PANTHER PTHR10366:SF401 259 301 1.3E-75 T 22-04-2016 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 Pfam PF11066 Protein of unknown function (DUF2867) 333 467 1.6E-28 T 22-04-2016 IPR021295 Protein of unknown function DUF2867 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 PANTHER PTHR10366 2 238 1.3E-75 T 22-04-2016 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 PANTHER PTHR10366 259 301 1.3E-75 T 22-04-2016 MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 Gene3D G3DSA:3.40.50.720 1 221 4.7E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 SUPERFAMILY SSF51735 1 291 6.88E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS05460 de5fbb0cfea3885c2dfbabf7a80942ec 478 Pfam PF13460 NAD(P)H-binding 7 145 4.5E-9 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS11640 872d7c094a3db6a9211ba82d07adbfd2 222 SUPERFAMILY SSF54001 53 218 1.54E-14 T 22-04-2016 MED134_RS11640 872d7c094a3db6a9211ba82d07adbfd2 222 PANTHER PTHR11039 53 218 1.2E-26 T 22-04-2016 MED134_RS11640 872d7c094a3db6a9211ba82d07adbfd2 222 SMART SM00460 110 176 2.1E-5 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS11640 872d7c094a3db6a9211ba82d07adbfd2 222 Pfam PF01841 Transglutaminase-like superfamily 50 174 2.3E-8 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS11640 872d7c094a3db6a9211ba82d07adbfd2 222 PANTHER PTHR11039:SF43 53 218 1.2E-26 T 22-04-2016 MED134_RS13775 f3634b3fa610de3104d4fe55cbaccad3 379 SUPERFAMILY SSF54001 36 370 3.39E-42 T 22-04-2016 MED134_RS13775 f3634b3fa610de3104d4fe55cbaccad3 379 Pfam PF03051 Peptidase C1-like family 132 377 2.5E-13 T 22-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 MED134_RS13775 f3634b3fa610de3104d4fe55cbaccad3 379 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 44 55 - T 22-04-2016 IPR000169 Cysteine peptidase, cysteine active site MED134_RS13775 f3634b3fa610de3104d4fe55cbaccad3 379 Gene3D G3DSA:3.90.70.10 35 377 4.2E-75 T 22-04-2016 MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 Gene3D G3DSA:2.40.50.140 85 147 1.9E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 Pfam PF00313 'Cold-shock' DNA-binding domain 86 146 1.5E-16 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 PRINTS PR00050 Cold shock protein signature 87 102 9.8E-7 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 PRINTS PR00050 Cold shock protein signature 120 138 9.8E-7 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 SMART SM00357 86 147 1.3E-10 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 MED134_RS01825 b8e5a8b804e62d3894cde04092985704 148 SUPERFAMILY SSF50249 82 147 2.14E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS01560 8e7063929c65bd43333b82800bd20794 188 SUPERFAMILY SSF101874 24 188 1.14E-27 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS01560 8e7063929c65bd43333b82800bd20794 188 Gene3D G3DSA:2.40.128.110 26 188 5.5E-28 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS01560 8e7063929c65bd43333b82800bd20794 188 SMART SM00867 26 187 4.0E-10 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS01560 8e7063929c65bd43333b82800bd20794 188 Pfam PF04264 YceI-like domain 29 188 8.6E-24 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS02800 452854748e2eb2b4c1bb5938edf1d0be 444 PANTHER PTHR33608:SF3 2 444 1.1E-116 T 22-04-2016 MED134_RS02800 452854748e2eb2b4c1bb5938edf1d0be 444 Pfam PF01882 Protein of unknown function DUF58 200 284 1.2E-20 T 22-04-2016 IPR002881 Domain of unknown function DUF58 MED134_RS02800 452854748e2eb2b4c1bb5938edf1d0be 444 PANTHER PTHR33608 2 444 1.1E-116 T 22-04-2016 MED134_RS02800 452854748e2eb2b4c1bb5938edf1d0be 444 SUPERFAMILY SSF53300 238 377 1.06E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 9 89 4.4E-13 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 PANTHER PTHR10815:SF2 6 108 1.6E-34 T 22-04-2016 MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 10 91 1.8E-23 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 SUPERFAMILY SSF46767 8 92 4.84E-22 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 Gene3D G3DSA:1.10.10.10 8 95 9.1E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10785 2e66c9b2efd00af3abf394b7fd30ee32 112 PANTHER PTHR10815 6 108 1.6E-34 T 22-04-2016 MED134_RS08375 de5456a08b0b54aad4539d1b02faff33 136 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 32 6.8E-4 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site MED134_RS08375 de5456a08b0b54aad4539d1b02faff33 136 Gene3D G3DSA:3.30.700.10 14 86 2.5E-6 T 22-04-2016 MED134_RS08375 de5456a08b0b54aad4539d1b02faff33 136 SUPERFAMILY SSF54523 16 92 3.92E-10 T 22-04-2016 MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 PIRSF PIRSF002161 3 183 2.0E-66 T 22-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 PANTHER PTHR11994 6 183 2.6E-81 T 22-04-2016 MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 4 182 41.975 T 22-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 Gene3D G3DSA:3.30.1440.10 5 182 6.8E-72 T 22-04-2016 IPR022803 Ribosomal protein L5 domain MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 PANTHER PTHR11994:SF4 6 183 2.6E-81 T 22-04-2016 MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 SUPERFAMILY SSF55282 6 182 7.53E-72 T 22-04-2016 IPR022803 Ribosomal protein L5 domain MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 Pfam PF00281 Ribosomal protein L5 27 83 1.8E-23 T 22-04-2016 IPR031310 Ribosomal protein L5, N-terminal MED134_RS12295 7bd5abe3f31f200d2ba789c552e72a17 183 Pfam PF00673 ribosomal L5P family C-terminus 87 180 8.8E-40 T 22-04-2016 IPR031309 Ribosomal protein L5, C-terminal MED134_RS14290 80dc6697f43975bff2aad9eb3cfea217 378 PANTHER PTHR13871 250 363 2.6E-25 T 22-04-2016 MED134_RS14290 80dc6697f43975bff2aad9eb3cfea217 378 SUPERFAMILY SSF52833 235 375 2.07E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14290 80dc6697f43975bff2aad9eb3cfea217 378 Gene3D G3DSA:3.40.30.10 237 373 4.7E-49 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14290 80dc6697f43975bff2aad9eb3cfea217 378 Pfam PF00578 AhpC/TSA family 238 359 4.8E-23 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS14290 80dc6697f43975bff2aad9eb3cfea217 378 Pfam PF14289 Domain of unknown function (DUF4369) 22 117 6.1E-11 T 22-04-2016 IPR025380 Domain of unknown function DUF4369 MED134_RS11140 a20b8b168bd2cd01ab0b1e4b1279fad6 99 Pfam PF00085 Thioredoxin 4 95 3.8E-14 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 MED134_RS11140 a20b8b168bd2cd01ab0b1e4b1279fad6 99 SUPERFAMILY SSF52833 4 97 1.26E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11140 a20b8b168bd2cd01ab0b1e4b1279fad6 99 Gene3D G3DSA:3.40.30.10 9 97 2.0E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS11140 a20b8b168bd2cd01ab0b1e4b1279fad6 99 PANTHER PTHR10438 11 99 2.8E-20 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MED134_RS12045 0bf3dec9f5df5e02513d31b65fc87eb3 156 Gene3D G3DSA:3.40.630.30 16 153 3.8E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS12045 0bf3dec9f5df5e02513d31b65fc87eb3 156 PANTHER PTHR23091 35 155 8.5E-19 T 22-04-2016 MED134_RS12045 0bf3dec9f5df5e02513d31b65fc87eb3 156 SUPERFAMILY SSF55729 14 155 1.06E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS12045 0bf3dec9f5df5e02513d31b65fc87eb3 156 Pfam PF13673 Acetyltransferase (GNAT) domain 46 154 8.6E-15 T 22-04-2016 IPR000182 GNAT domain GO:0008080 MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 SUPERFAMILY SSF51735 2 282 4.13E-90 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 282 2.6E-94 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 Pfam PF04321 RmlD substrate binding domain 2 282 9.9E-100 T 22-04-2016 IPR029903 RmlD-like substrate binding domain MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 Gene3D G3DSA:3.40.50.720 2 229 4.3E-59 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 PANTHER PTHR10491:SF4 2 281 3.6E-93 T 22-04-2016 MED134_RS01355 1e457f78b5980c220c7a67b0a1244fe6 284 PANTHER PTHR10491 2 281 3.6E-93 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family MED134_RS00625 a03323eccbc634cd7e101ccf4a259c22 868 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 791 867 8.5E-10 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS00625 a03323eccbc634cd7e101ccf4a259c22 868 SUPERFAMILY SSF101898 42 236 1.12E-10 T 22-04-2016 MED134_RS00625 a03323eccbc634cd7e101ccf4a259c22 868 Gene3D G3DSA:2.120.10.30 98 251 2.2E-8 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS03240 83999269155f7537acb047dcfb8d1133 341 Pfam PF01032 FecCD transport family 17 335 1.5E-80 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 MED134_RS03240 83999269155f7537acb047dcfb8d1133 341 Gene3D G3DSA:1.10.3470.10 3 338 2.0E-93 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS03240 83999269155f7537acb047dcfb8d1133 341 PANTHER PTHR30472 5 341 9.3E-114 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 MED134_RS03240 83999269155f7537acb047dcfb8d1133 341 SUPERFAMILY SSF81345 5 335 1.12E-68 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS03240 83999269155f7537acb047dcfb8d1133 341 PANTHER PTHR30472:SF32 5 341 9.3E-114 T 22-04-2016 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 SUPERFAMILY SSF51621 9 383 2.74E-126 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 SUPERFAMILY SSF51621 420 505 2.74E-126 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 PANTHER PTHR21631 437 536 9.7E-70 T 22-04-2016 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 PANTHER PTHR21631 308 400 9.7E-70 T 22-04-2016 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 PANTHER PTHR21631 96 257 9.7E-70 T 22-04-2016 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Gene3D G3DSA:3.20.20.60 15 261 8.4E-138 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Gene3D G3DSA:3.20.20.60 420 503 8.4E-138 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Gene3D G3DSA:3.20.20.60 294 383 8.4E-138 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Pfam PF00463 Isocitrate lyase family 431 521 4.9E-12 T 22-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Pfam PF00463 Isocitrate lyase family 98 261 5.2E-23 T 22-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 MED134_RS05540 cf24cf98a07f5b3219f5d75f5ab3bbbd 536 Pfam PF00463 Isocitrate lyase family 308 384 3.4E-11 T 22-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 MED134_RS03495 bdfcf2768ccca64dca573f9e8f67716c 351 SUPERFAMILY SSF53300 114 297 9.64E-17 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS03495 bdfcf2768ccca64dca573f9e8f67716c 351 Gene3D G3DSA:3.40.50.410 116 297 1.1E-7 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS03495 bdfcf2768ccca64dca573f9e8f67716c 351 Pfam PF00092 von Willebrand factor type A domain 116 292 9.0E-10 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS03495 bdfcf2768ccca64dca573f9e8f67716c 351 SMART SM00327 111 296 1.5E-8 T 22-04-2016 IPR002035 von Willebrand factor, type A MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 Pfam PF00582 Universal stress protein family 198 276 1.6E-5 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 Pfam PF00582 Universal stress protein family 1 146 8.9E-16 T 22-04-2016 IPR006016 UspA GO:0006950 MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 SUPERFAMILY SSF52402 200 276 3.18E-7 T 22-04-2016 MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 SUPERFAMILY SSF52402 1 153 2.68E-24 T 22-04-2016 MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 PRINTS PR01438 Universal stress protein signature 124 146 3.2E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 PRINTS PR01438 Universal stress protein signature 1 9 3.2E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 PRINTS PR01438 Universal stress protein signature 106 118 3.2E-7 T 22-04-2016 IPR006015 Universal stress protein A MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 Gene3D G3DSA:3.40.50.620 210 276 2.4E-6 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS04690 9ae9f97bf77c9d550a670324e78742fd 283 Gene3D G3DSA:3.40.50.620 1 148 1.6E-21 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS05850 be436247724a2ea3c185af2326b12377 204 SUPERFAMILY SSF100950 39 201 8.37E-14 T 22-04-2016 MED134_RS05850 be436247724a2ea3c185af2326b12377 204 Gene3D G3DSA:3.40.50.10420 39 174 1.6E-7 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain MED134_RS05850 be436247724a2ea3c185af2326b12377 204 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 102 191 1.7E-6 T 22-04-2016 IPR003741 LUD domain MED134_RS12960 3be52773cd413bf7e9d93df1a81c583f 583 Gene3D G3DSA:3.40.630.10 39 320 1.3E-21 T 22-04-2016 MED134_RS12960 3be52773cd413bf7e9d93df1a81c583f 583 PANTHER PTHR11705 26 360 3.5E-20 T 22-04-2016 MED134_RS12960 3be52773cd413bf7e9d93df1a81c583f 583 SUPERFAMILY SSF53187 38 313 2.13E-35 T 22-04-2016 MED134_RS12960 3be52773cd413bf7e9d93df1a81c583f 583 PANTHER PTHR11705:SF82 26 360 3.5E-20 T 22-04-2016 MED134_RS05360 32b942d02381c8029c21bbdbaf2c4464 141 Gene3D G3DSA:1.10.760.10 38 138 4.5E-24 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS05360 32b942d02381c8029c21bbdbaf2c4464 141 SUPERFAMILY SSF46626 1 130 6.95E-22 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS05360 32b942d02381c8029c21bbdbaf2c4464 141 Pfam PF00034 Cytochrome c 37 122 1.0E-9 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS01405 5e3d9faea47441825e51596f5a0f2f92 624 PANTHER PTHR39210 99 567 4.3E-21 T 22-04-2016 MED134_RS01405 5e3d9faea47441825e51596f5a0f2f92 624 SUPERFAMILY SSF48230 99 368 1.33E-23 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase MED134_RS01405 5e3d9faea47441825e51596f5a0f2f92 624 Pfam PF07940 Heparinase II/III-like protein 409 580 8.9E-28 T 22-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 MED134_RS01405 5e3d9faea47441825e51596f5a0f2f92 624 Pfam PF16889 Heparinase II/III N-terminus 135 321 5.5E-16 T 22-04-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 MED134_RS06135 a890251a0d134df56ec4685a2e1b0724 170 Pfam PF04390 Lipopolysaccharide-assembly 12 164 3.6E-16 T 22-04-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MED134_RS02750 2efbb85bb6e6124c83e0a8a0c1dbf10a 411 PANTHER PTHR30572 4 411 7.5E-75 T 22-04-2016 MED134_RS02750 2efbb85bb6e6124c83e0a8a0c1dbf10a 411 Pfam PF12704 MacB-like periplasmic core domain 23 247 2.0E-30 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS02750 2efbb85bb6e6124c83e0a8a0c1dbf10a 411 Pfam PF02687 FtsX-like permease family 292 404 8.5E-21 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS11705 07a185d3c24e83b4d003bdbe935caf44 169 Pfam PF05163 DinB family 13 146 1.3E-4 T 22-04-2016 IPR007837 DNA damage-inducible protein DinB MED134_RS11705 07a185d3c24e83b4d003bdbe935caf44 169 SUPERFAMILY SSF109854 17 149 6.23E-7 T 22-04-2016 MED134_RS11705 07a185d3c24e83b4d003bdbe935caf44 169 Gene3D G3DSA:1.20.120.450 25 149 1.8E-4 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS10280 4de3ce29cb0e20e5558435565186721f 370 Gene3D G3DSA:1.10.3470.10 49 274 5.2E-12 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS10280 4de3ce29cb0e20e5558435565186721f 370 PANTHER PTHR30477 9 311 2.5E-108 T 22-04-2016 MED134_RS10280 4de3ce29cb0e20e5558435565186721f 370 PANTHER PTHR30477:SF3 9 311 2.5E-108 T 22-04-2016 MED134_RS10280 4de3ce29cb0e20e5558435565186721f 370 SUPERFAMILY SSF81345 15 273 2.35E-30 T 22-04-2016 IPR029022 ABC transporter, BtuC-like MED134_RS10280 4de3ce29cb0e20e5558435565186721f 370 Pfam PF00950 ABC 3 transport family 14 278 4.0E-74 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 MED134_RS02360 d51e5b43a969c03936ef6700f9410faf 193 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 56 191 3.9E-37 T 22-04-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS02360 d51e5b43a969c03936ef6700f9410faf 193 Gene3D G3DSA:2.60.40.200 52 191 3.6E-41 T 22-04-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS02360 d51e5b43a969c03936ef6700f9410faf 193 SUPERFAMILY SSF49329 49 191 6.81E-40 T 22-04-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 MED134_RS02360 d51e5b43a969c03936ef6700f9410faf 193 PANTHER PTHR10003 54 189 3.7E-21 T 22-04-2016 IPR024134 Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone MetaCyc: PWY-6854 MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 PANTHER PTHR22935 1 187 3.3E-34 T 22-04-2016 MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 26 201 26.605 T 22-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 Gene3D G3DSA:3.30.1380.10 24 193 2.6E-54 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 SUPERFAMILY SSF55166 25 199 2.41E-49 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 PIRSF PIRSF026671 4 199 2.2E-49 T 22-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 Pfam PF01427 D-ala-D-ala dipeptidase 27 190 2.8E-32 T 22-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 MED134_RS03515 7d91b86bbb8b85168c3f70a4d598de82 205 PANTHER PTHR22935:SF81 1 187 3.3E-34 T 22-04-2016 MED134_RS09980 b5db2f6fb237edd43e47b2caef6f9a85 241 PANTHER PTHR24032:SF31 2 227 1.8E-21 T 22-04-2016 MED134_RS09980 b5db2f6fb237edd43e47b2caef6f9a85 241 Gene3D G3DSA:3.60.21.10 1 228 1.2E-41 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS09980 b5db2f6fb237edd43e47b2caef6f9a85 241 PANTHER PTHR24032 2 227 1.8E-21 T 22-04-2016 MED134_RS09980 b5db2f6fb237edd43e47b2caef6f9a85 241 Pfam PF00149 Calcineurin-like phosphoesterase 1 141 2.2E-14 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 MED134_RS09980 b5db2f6fb237edd43e47b2caef6f9a85 241 SUPERFAMILY SSF56300 1 218 5.17E-36 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 PANTHER PTHR11808:SF15 15 391 8.5E-138 T 22-04-2016 MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 SUPERFAMILY SSF53383 13 379 4.76E-86 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 379 6.9E-97 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 Gene3D G3DSA:3.40.640.10 18 234 5.1E-73 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 Gene3D G3DSA:3.90.1150.10 256 380 2.6E-28 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 PANTHER PTHR11808 15 391 8.5E-138 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS04145 6f178f60ce38742e9f29f3f701531a69 404 PIRSF PIRSF001434 2 396 3.1E-103 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.112 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 PANTHER PTHR23321 1 88 1.8E-34 T 22-04-2016 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 Gene3D G3DSA:1.10.287.10 2 89 1.3E-36 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 Pfam PF00312 Ribosomal protein S15 8 88 1.8E-32 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 SUPERFAMILY SSF47060 2 89 1.0E-32 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 9.5E-32 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 SMART SM01387 8 88 1.5E-43 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 4.0E-30 T 22-04-2016 MED134_RS05635 6352891e3f4649bdb8fec323761560ae 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Pfam PF08245 Mur ligase middle domain 108 280 9.2E-18 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 PANTHER PTHR23135 1 378 1.2E-59 T 22-04-2016 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Gene3D G3DSA:3.90.190.20 306 441 4.8E-24 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 SUPERFAMILY SSF53623 93 301 4.73E-35 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Gene3D G3DSA:3.40.1190.10 92 305 8.0E-47 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 PANTHER PTHR23135:SF5 1 378 1.2E-59 T 22-04-2016 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Gene3D G3DSA:3.40.50.720 1 91 1.1E-22 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 305 380 2.0E-5 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 SUPERFAMILY SSF53244 303 445 5.49E-29 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 Pfam PF01225 Mur ligase family, catalytic domain 3 102 3.8E-10 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 MED134_RS12800 517a0f4adebc7bac080a56412e6e1567 450 SUPERFAMILY SSF51984 1 91 1.7E-16 T 22-04-2016 MED134_RS06785 eaff21b81b15ccd00c08026d7a168425 166 Gene3D G3DSA:2.60.40.10 61 138 8.7E-4 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS11635 07ea2b01e0657fdf3c430135abbf816e 387 Pfam PF00144 Beta-lactamase 47 362 4.4E-43 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS11635 07ea2b01e0657fdf3c430135abbf816e 387 PANTHER PTHR22935 45 379 1.0E-42 T 22-04-2016 MED134_RS11635 07ea2b01e0657fdf3c430135abbf816e 387 SUPERFAMILY SSF56601 39 372 1.99E-56 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS11635 07ea2b01e0657fdf3c430135abbf816e 387 Gene3D G3DSA:3.40.710.10 27 368 1.2E-55 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS12875 369655512af20cfb2a7f56c6c9089548 155 Pfam PF04116 Fatty acid hydroxylase superfamily 10 141 8.4E-12 T 22-04-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 MED134_RS12875 369655512af20cfb2a7f56c6c9089548 155 PANTHER PTHR31899 11 126 2.6E-21 T 22-04-2016 MED134_RS01880 5e9a6a580dd9024406541de10761a6ba 374 Gene3D G3DSA:2.120.10.10 103 339 2.0E-17 T 22-04-2016 IPR011040 Sialidases MED134_RS01880 5e9a6a580dd9024406541de10761a6ba 374 SUPERFAMILY SSF50939 122 345 3.53E-25 T 22-04-2016 IPR011040 Sialidases MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 PANTHER PTHR30471 10 237 1.0E-90 T 22-04-2016 MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 186 191 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 Pfam PF04002 RadC-like JAB domain 116 235 1.0E-41 T 22-04-2016 IPR025657 RadC-like JAB domain MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 TIGRFAM TIGR00608 radc: DNA repair protein RadC 23 237 3.6E-60 T 22-04-2016 IPR001405 RadC protein MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 PANTHER PTHR30471:SF3 10 237 1.0E-90 T 22-04-2016 MED134_RS12140 c44eb1f9aca6c7c9e19fbd025db97b7e 237 Gene3D G3DSA:3.40.140.10 113 237 8.7E-45 T 22-04-2016 MED134_RS11460 96837ac7b7f6a0b60109905d5fdf1df1 314 Gene3D G3DSA:3.40.50.1110 111 259 9.6E-5 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS11460 96837ac7b7f6a0b60109905d5fdf1df1 314 Pfam PF08885 GSCFA family 21 256 8.4E-89 T 22-04-2016 IPR014982 GSCFA MED134_RS11460 96837ac7b7f6a0b60109905d5fdf1df1 314 SUPERFAMILY SSF52266 156 257 1.25E-5 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain MED134_RS01390 0ebc8162392ea82f9fe2110c82d86b87 424 Pfam PF04932 O-Antigen ligase 205 343 8.7E-9 T 22-04-2016 IPR007016 O-antigen ligase-related MED134_RS06505 615ad37e36e0d54df5d5235f1a50382e 415 Gene3D G3DSA:2.40.160.60 42 390 1.6E-24 T 22-04-2016 MED134_RS06505 615ad37e36e0d54df5d5235f1a50382e 415 SUPERFAMILY SSF56935 54 409 1.4E-5 T 22-04-2016 MED134_RS04205 fe66afddf5db536524c045a4cdbc81e2 247 SUPERFAMILY SSF49464 143 219 3.14E-11 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS04205 fe66afddf5db536524c045a4cdbc81e2 247 Gene3D G3DSA:2.60.40.1120 144 222 6.3E-7 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS04205 fe66afddf5db536524c045a4cdbc81e2 247 Pfam PF13715 CarboxypepD_reg-like domain 144 222 4.3E-9 T 22-04-2016 MED134_RS03340 1c9772f3dab2f84c35e5db2614a900f3 187 PANTHER PTHR30305 13 185 2.2E-65 T 22-04-2016 MED134_RS03340 1c9772f3dab2f84c35e5db2614a900f3 187 SUPERFAMILY SSF82057 113 185 4.39E-22 T 22-04-2016 MED134_RS03340 1c9772f3dab2f84c35e5db2614a900f3 187 Gene3D G3DSA:2.30.30.40 117 185 3.5E-23 T 22-04-2016 MED134_RS03340 1c9772f3dab2f84c35e5db2614a900f3 187 Pfam PF03831 PhnA domain 119 185 7.7E-26 T 22-04-2016 IPR013988 PhnA protein, C-terminal MED134_RS03340 1c9772f3dab2f84c35e5db2614a900f3 187 PANTHER PTHR30305:SF2 13 185 2.2E-65 T 22-04-2016 MED134_RS08870 b8e057b76872fd31a019bbd458c427d5 127 PANTHER PTHR33823 6 127 6.1E-20 T 22-04-2016 MED134_RS08870 b8e057b76872fd31a019bbd458c427d5 127 SUPERFAMILY SSF109635 3 94 3.01E-6 T 22-04-2016 MED134_RS08870 b8e057b76872fd31a019bbd458c427d5 127 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 93 122 4.3E-6 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MED134_RS07080 d336242a105a228be89af57b0324333b 321 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 19 319 4.0E-91 T 22-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 MED134_RS07080 d336242a105a228be89af57b0324333b 321 Gene3D G3DSA:3.20.20.220 3 318 9.8E-87 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like MED134_RS07080 d336242a105a228be89af57b0324333b 321 SUPERFAMILY SSF51730 7 317 3.34E-81 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like MED134_RS07080 d336242a105a228be89af57b0324333b 321 Pfam PF02219 Methylenetetrahydrofolate reductase 9 318 1.5E-64 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 MED134_RS07080 d336242a105a228be89af57b0324333b 321 PANTHER PTHR21091 180 283 2.3E-30 T 22-04-2016 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 SUPERFAMILY SSF48452 25 98 1.52E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 Pfam PF08239 Bacterial SH3 domain 204 249 2.5E-7 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 SMART SM00028 59 92 4.1E-4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 SMART SM00028 25 58 0.0017 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 Gene3D G3DSA:1.25.40.10 23 98 3.1E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 Pfam PF13432 Tetratricopeptide repeat 31 92 2.4E-9 T 22-04-2016 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 Gene3D G3DSA:2.30.30.40 218 249 2.9E-4 T 22-04-2016 MED134_RS09925 c682c8354f7c0b9d690eceb25b80045f 254 SMART SM00287 192 254 8.0E-4 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type MED134_RS13395 8499d488fc7e948f2cd88ef1e99e5cbb 361 PANTHER PTHR41244:SF1 5 360 2.9E-101 T 22-04-2016 MED134_RS13395 8499d488fc7e948f2cd88ef1e99e5cbb 361 Pfam PF14307 Glycosyltransferase WbsX 8 355 2.4E-128 T 22-04-2016 IPR032719 Glycosyltransferase WbsX MED134_RS13395 8499d488fc7e948f2cd88ef1e99e5cbb 361 PANTHER PTHR41244 5 360 2.9E-101 T 22-04-2016 MED134_RS09755 3fedb8a97739feb1984ea70a8ff7eb4a 158 PANTHER PTHR31793 1 145 3.9E-19 T 22-04-2016 MED134_RS09755 3fedb8a97739feb1984ea70a8ff7eb4a 158 SUPERFAMILY SSF54637 1 151 6.68E-31 T 22-04-2016 IPR029069 HotDog domain MED134_RS09755 3fedb8a97739feb1984ea70a8ff7eb4a 158 Pfam PF13279 Thioesterase-like superfamily 9 126 1.7E-12 T 22-04-2016 MED134_RS09755 3fedb8a97739feb1984ea70a8ff7eb4a 158 Gene3D G3DSA:3.10.129.10 2 131 1.3E-22 T 22-04-2016 IPR029069 HotDog domain MED134_RS13645 07937b6c37a63ed6e1edc238b8c05796 292 Gene3D G3DSA:3.90.550.10 2 193 1.1E-20 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13645 07937b6c37a63ed6e1edc238b8c05796 292 SUPERFAMILY SSF53448 1 217 1.66E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS13645 07937b6c37a63ed6e1edc238b8c05796 292 PANTHER PTHR22916 1 200 1.8E-16 T 22-04-2016 MED134_RS13645 07937b6c37a63ed6e1edc238b8c05796 292 Pfam PF00535 Glycosyl transferase family 2 3 163 8.9E-15 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 PANTHER PTHR21666:SF186 19 216 1.2E-20 T 22-04-2016 MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 SUPERFAMILY SSF54001 116 227 2.03E-32 T 22-04-2016 MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 Pfam PF08239 Bacterial SH3 domain 13 61 6.4E-8 T 22-04-2016 IPR003646 SH3-like domain, bacterial-type MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 Gene3D G3DSA:2.30.30.40 21 64 1.2E-4 T 22-04-2016 MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 Gene3D G3DSA:3.90.1720.10 117 230 7.1E-34 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 PANTHER PTHR21666 19 216 1.2E-20 T 22-04-2016 MED134_RS01960 30b2a0c9c4d79ccd292bab7d92d66570 249 Pfam PF00877 NlpC/P60 family 137 230 7.9E-21 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- MED134_RS00395 d42a121ab580923d6f640e0d647acb06 454 PIRSF PIRSF005850 4 454 1.4E-127 T 22-04-2016 IPR019219 Protein of unknown function DUF2130 MED134_RS00395 d42a121ab580923d6f640e0d647acb06 454 Pfam PF09903 Uncharacterized protein conserved in bacteria (DUF2130) 185 441 6.2E-97 T 22-04-2016 IPR019219 Protein of unknown function DUF2130 MED134_RS10245 5811886910bff20eb96c26686044738a 269 Pfam PF13715 CarboxypepD_reg-like domain 25 102 1.6E-8 T 22-04-2016 MED134_RS10245 5811886910bff20eb96c26686044738a 269 SUPERFAMILY SSF49464 25 88 1.83E-5 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS10245 5811886910bff20eb96c26686044738a 269 Gene3D G3DSA:2.60.40.1120 25 107 4.1E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS11725 74f6084b1d9669f7d17988993fc597a4 96 SUPERFAMILY SSF102829 7 95 4.05E-13 T 22-04-2016 IPR007838 Cell division protein ZapA-like MED134_RS11725 74f6084b1d9669f7d17988993fc597a4 96 Pfam PF05164 Cell division protein ZapA 7 89 1.6E-19 T 22-04-2016 IPR007838 Cell division protein ZapA-like MED134_RS04875 e2e76dad787bc0ea5651001f72591bc9 106 Pfam PF11950 Protein of unknown function (DUF3467) 2 89 9.4E-30 T 22-04-2016 IPR021857 Protein of unknown function DUF3467 MED134_RS03665 e988cd3a790a6b0a65a675f74fddf211 307 Gene3D G3DSA:3.40.50.1820 54 284 2.0E-37 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03665 e988cd3a790a6b0a65a675f74fddf211 307 Pfam PF07859 alpha/beta hydrolase fold 83 276 3.2E-8 T 22-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 MED134_RS03665 e988cd3a790a6b0a65a675f74fddf211 307 SUPERFAMILY SSF53474 45 285 1.08E-32 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00030 e5ddc2db0314064640446985296a136c 136 PIRSF PIRSF006113 1 136 1.2E-18 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein MED134_RS00030 e5ddc2db0314064640446985296a136c 136 Gene3D G3DSA:3.30.479.10 2 135 4.1E-45 T 22-04-2016 MED134_RS00030 e5ddc2db0314064640446985296a136c 136 SUPERFAMILY SSF55620 2 136 4.78E-47 T 22-04-2016 MED134_RS00030 e5ddc2db0314064640446985296a136c 136 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 136 7.5E-35 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein MED134_RS00030 e5ddc2db0314064640446985296a136c 136 PANTHER PTHR12589 7 136 1.3E-51 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein MED134_RS12670 c886e826d80a2a87fb84bbe308062a50 233 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 21 229 1.2E-30 T 22-04-2016 MED134_RS12670 c886e826d80a2a87fb84bbe308062a50 233 PANTHER PTHR23291 7 233 2.2E-22 T 22-04-2016 IPR006214 Bax inhibitor 1-related MED134_RS04840 c1bf056d1b069984a62955d7877cdc15 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 72 4.3E-13 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain MED134_RS04840 c1bf056d1b069984a62955d7877cdc15 98 SUPERFAMILY SSF54909 1 91 9.08E-23 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel MED134_RS04840 c1bf056d1b069984a62955d7877cdc15 98 Gene3D G3DSA:3.30.70.900 1 89 6.0E-17 T 22-04-2016 MED134_RS04180 89efaeebfa401715049ead52603c623f 821 Pfam PF09397 Ftsk gamma domain 748 808 1.4E-25 T 22-04-2016 IPR018541 FtsK gamma domain MED134_RS04180 89efaeebfa401715049ead52603c623f 821 SMART SM00843 746 811 2.4E-30 T 22-04-2016 IPR018541 FtsK gamma domain MED134_RS04180 89efaeebfa401715049ead52603c623f 821 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 26 184 1.1E-20 T 22-04-2016 IPR025199 DNA translocase FtsK, 4TM region MED134_RS04180 89efaeebfa401715049ead52603c623f 821 Gene3D G3DSA:3.40.50.300 417 711 9.9E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS04180 89efaeebfa401715049ead52603c623f 821 PANTHER PTHR22683:SF41 200 821 1.5E-180 T 22-04-2016 MED134_RS04180 89efaeebfa401715049ead52603c623f 821 Pfam PF01580 FtsK/SpoIIIE family 444 647 7.1E-46 T 22-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MED134_RS04180 89efaeebfa401715049ead52603c623f 821 PANTHER PTHR22683 200 821 1.5E-180 T 22-04-2016 MED134_RS04180 89efaeebfa401715049ead52603c623f 821 SUPERFAMILY SSF46785 747 809 1.07E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS04180 89efaeebfa401715049ead52603c623f 821 SUPERFAMILY SSF52540 415 717 4.87E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 Gene3D G3DSA:3.40.30.10 7 24 1.4E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 Gene3D G3DSA:3.40.30.10 94 235 1.4E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 PANTHER PTHR10681:SF68 51 217 2.9E-15 T 22-04-2016 MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 SUPERFAMILY SSF52833 96 235 2.2E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 Pfam PF00578 AhpC/TSA family 97 211 2.3E-15 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS14630 f8306c800c8b659f87af1fa963bbc3dc 242 PANTHER PTHR10681 51 217 2.9E-15 T 22-04-2016 MED134_RS00070 77b072a426cb4234d4a7e65731a1b171 257 Gene3D G3DSA:1.10.575.10 22 256 1.0E-67 T 22-04-2016 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 MED134_RS00070 77b072a426cb4234d4a7e65731a1b171 257 Pfam PF02265 S1/P1 Nuclease 22 256 7.7E-69 T 22-04-2016 IPR003154 S1/P1 nuclease GO:0003676|GO:0004519|GO:0006308 MED134_RS00070 77b072a426cb4234d4a7e65731a1b171 257 SUPERFAMILY SSF48537 22 255 4.84E-62 T 22-04-2016 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 MED134_RS00070 77b072a426cb4234d4a7e65731a1b171 257 PANTHER PTHR33146 1 256 1.2E-52 T 22-04-2016 MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 Pfam PF00571 CBS domain 23 77 9.7E-12 T 22-04-2016 IPR000644 CBS domain MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 Pfam PF00571 CBS domain 96 145 4.9E-10 T 22-04-2016 IPR000644 CBS domain MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 SUPERFAMILY SSF54631 19 145 7.93E-35 T 22-04-2016 MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 SMART SM00116 30 78 1.4E-6 T 22-04-2016 IPR000644 CBS domain MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 SMART SM00116 99 146 2.4E-9 T 22-04-2016 IPR000644 CBS domain MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 Gene3D G3DSA:3.10.580.10 20 145 9.7E-32 T 22-04-2016 MED134_RS09700 849d63bff44fec59d521bc71651e1436 154 PANTHER PTHR11911 20 147 5.5E-30 T 22-04-2016 MED134_RS10490 8cdb2824fbda514c6454353451ef0378 487 Gene3D G3DSA:1.25.40.10 207 430 2.7E-31 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10490 8cdb2824fbda514c6454353451ef0378 487 SUPERFAMILY SSF48452 18 487 1.77E-96 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS10490 8cdb2824fbda514c6454353451ef0378 487 Pfam PF14322 Starch-binding associating with outer membrane 22 225 1.6E-24 T 22-04-2016 MED134_RS10490 8cdb2824fbda514c6454353451ef0378 487 Pfam PF07980 SusD family 333 487 1.1E-27 T 22-04-2016 IPR012944 RagB/SusD domain MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 Gene3D G3DSA:2.60.120.10 13 144 1.4E-19 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 Gene3D G3DSA:1.10.10.10 149 211 2.0E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 PANTHER PTHR24567 1 211 3.2E-24 T 22-04-2016 MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 SMART SM00419 161 209 2.9E-5 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 SUPERFAMILY SSF51206 12 144 4.58E-23 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 SUPERFAMILY SSF46785 143 211 7.87E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS12615 8536d0061f83579bfa6ee7119f8feffb 211 Pfam PF13545 Crp-like helix-turn-helix domain 149 211 4.6E-9 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MED134_RS02090 a89c58b174d7ed1b82c50443cff19ba4 259 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 191 258 1.4E-14 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS00180 2efae0dd71e66718141c7b894522148b 124 Gene3D G3DSA:3.30.1050.10 26 106 3.3E-4 T 22-04-2016 IPR003033 SCP2 sterol-binding domain MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 Pfam PF08281 Sigma-70, region 4 109 158 4.3E-8 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 PANTHER PTHR30173:SF8 1 163 1.8E-48 T 22-04-2016 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 Gene3D G3DSA:1.10.1740.10 6 104 2.0E-23 T 22-04-2016 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 SUPERFAMILY SSF88659 102 163 2.06E-8 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 Pfam PF04542 Sigma-70 region 2 12 79 7.0E-16 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 162 1.3E-26 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 Gene3D G3DSA:1.10.10.10 105 163 5.3E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 PANTHER PTHR30173 1 163 1.8E-48 T 22-04-2016 MED134_RS00155 32a01494549b18b584758ffade75f3d6 164 SUPERFAMILY SSF88946 6 90 3.01E-22 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS03950 81ecc262d3a1b21567be9c89df8d66e9 373 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 189 362 1.7E-16 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MED134_RS03950 81ecc262d3a1b21567be9c89df8d66e9 373 Gene3D G3DSA:3.30.70.1230 186 368 1.1E-22 T 22-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MED134_RS03950 81ecc262d3a1b21567be9c89df8d66e9 373 SUPERFAMILY SSF55073 183 366 2.35E-35 T 22-04-2016 IPR029787 Nucleotide cyclase MED134_RS00285 f5a8479c0d1d5fb4eb1d1dc75195862f 287 Pfam PF15461 Beta-carotene 15,15'-dioxygenase 30 285 2.5E-50 T 22-04-2016 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 MED134_RS00285 f5a8479c0d1d5fb4eb1d1dc75195862f 287 TIGRFAM TIGR03753 blh_monoox: beta-carotene 15,15'-monooxygenase, Brp/Blh family 26 282 2.7E-60 T 22-04-2016 IPR022270 Beta-carotene 15,15'-monooxygenase, Brp/Blh family GO:0016702|GO:0055114 KEGG: 00830+1.13.11.63|MetaCyc: PWY-6857 MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 Gene3D G3DSA:3.40.250.10 144 263 2.2E-35 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 SUPERFAMILY SSF52821 2 121 1.83E-30 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 SUPERFAMILY SSF52821 147 262 2.75E-29 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 Gene3D G3DSA:3.40.250.10 2 139 2.3E-34 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 Pfam PF00581 Rhodanese-like domain 8 118 5.9E-16 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 Pfam PF00581 Rhodanese-like domain 148 260 7.0E-11 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 PANTHER PTHR11364 1 263 1.1E-98 T 22-04-2016 MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 SMART SM00450 6 121 2.2E-15 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 SMART SM00450 140 264 1.3E-8 T 22-04-2016 IPR001763 Rhodanese-like domain MED134_RS06770 1b96bc967135596b947d9b55c663e52d 268 PANTHER PTHR11364:SF13 1 263 1.1E-98 T 22-04-2016 MED134_RS08425 d6015ccd427baf73cd170670c6224983 198 Gene3D G3DSA:3.40.50.300 27 189 3.0E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS08425 d6015ccd427baf73cd170670c6224983 198 SUPERFAMILY SSF52540 25 191 2.73E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00345 a88e2b791e58d5ccb8ef404d56ad2fd0 598 Gene3D G3DSA:3.40.50.300 1 181 3.5E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00345 a88e2b791e58d5ccb8ef404d56ad2fd0 598 Gene3D G3DSA:3.40.50.300 279 401 3.5E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00345 a88e2b791e58d5ccb8ef404d56ad2fd0 598 Pfam PF13175 AAA ATPase domain 1 398 8.7E-49 T 22-04-2016 MED134_RS00345 a88e2b791e58d5ccb8ef404d56ad2fd0 598 SUPERFAMILY SSF52540 238 401 1.35E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS00345 a88e2b791e58d5ccb8ef404d56ad2fd0 598 SUPERFAMILY SSF52540 1 180 1.35E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS10860 d0ceb16f24d063c7fc806c2f6e6e263e 114 Pfam PF03724 META domain 7 98 1.3E-15 T 22-04-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 Pfam PF00005 ABC transporter 18 157 5.7E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 Gene3D G3DSA:3.40.50.300 2 222 3.1E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 PANTHER PTHR24220 4 233 5.4E-83 T 22-04-2016 MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 TIGRFAM TIGR03522 GldA_ABC_ATP: gliding motility-associated ABC transporter ATP-binding subunit GldA 1 296 8.8E-142 T 22-04-2016 IPR019864 Gliding motility-associated ABC transporter ATP-binding subunit GldA MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 SMART SM00382 27 207 2.1E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain MED134_RS05625 ba307bd95a26fb1f94e0a643d328b225 297 SUPERFAMILY SSF52540 3 220 1.21E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS02170 36c84806c2e538762a91bc81f9c2a6ca 317 Pfam PF02661 Fic/DOC family 99 194 1.8E-19 T 22-04-2016 IPR003812 Fido domain MED134_RS02170 36c84806c2e538762a91bc81f9c2a6ca 317 PANTHER PTHR13504 37 288 3.2E-40 T 22-04-2016 MED134_RS02170 36c84806c2e538762a91bc81f9c2a6ca 317 SUPERFAMILY SSF140931 76 255 5.75E-38 T 22-04-2016 IPR003812 Fido domain MED134_RS02170 36c84806c2e538762a91bc81f9c2a6ca 317 Gene3D G3DSA:1.10.3290.10 13 259 4.6E-59 T 22-04-2016 IPR003812 Fido domain MED134_RS07810 9e66cf9fae6eedb30a89e1d3f51a468c 333 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 177 2.7E-30 T 22-04-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MED134_RS07810 9e66cf9fae6eedb30a89e1d3f51a468c 333 PANTHER PTHR40031 2 329 8.3E-30 T 22-04-2016 MED134_RS07810 9e66cf9fae6eedb30a89e1d3f51a468c 333 PANTHER PTHR40031:SF1 2 329 8.3E-30 T 22-04-2016 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 PANTHER PTHR21294 1 246 7.2E-57 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 PIRSF PIRSF000090 1 246 1.1E-49 T 22-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 PANTHER PTHR21294:SF0 1 246 7.2E-57 T 22-04-2016 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 SUPERFAMILY SSF52402 1 241 1.83E-62 T 22-04-2016 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 Pfam PF01012 Electron transfer flavoprotein domain 25 206 4.5E-37 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 Gene3D G3DSA:3.40.50.620 1 244 9.7E-69 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS07205 62383436b8e3fb19c30c537d7481dbf6 246 SMART SM00893 23 212 2.1E-37 T 22-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 MED134_RS11820 76b92240e882cd4dfa943c7c5f560e4c 229 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 61 75 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS11820 76b92240e882cd4dfa943c7c5f560e4c 229 Pfam PF00849 RNA pseudouridylate synthase 16 171 3.0E-35 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS11820 76b92240e882cd4dfa943c7c5f560e4c 229 SUPERFAMILY SSF55120 8 220 1.17E-54 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MED134_RS11820 76b92240e882cd4dfa943c7c5f560e4c 229 PANTHER PTHR11079:SF83 10 225 2.1E-76 T 22-04-2016 MED134_RS11820 76b92240e882cd4dfa943c7c5f560e4c 229 PANTHER PTHR11079 10 225 2.1E-76 T 22-04-2016 MED134_RS01790 b9d2fa54fea0480df50522c4f1ec5b47 366 PANTHER PTHR22893:SF14 4 366 3.2E-157 T 22-04-2016 MED134_RS01790 b9d2fa54fea0480df50522c4f1ec5b47 366 Gene3D G3DSA:3.20.20.70 4 363 1.5E-125 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS01790 b9d2fa54fea0480df50522c4f1ec5b47 366 PANTHER PTHR22893 4 366 3.2E-157 T 22-04-2016 MED134_RS01790 b9d2fa54fea0480df50522c4f1ec5b47 366 SUPERFAMILY SSF51395 4 363 8.31E-114 T 22-04-2016 MED134_RS01790 b9d2fa54fea0480df50522c4f1ec5b47 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 340 9.4E-85 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MED134_RS05365 5426e046178e05594344e16811885b16 370 Gene3D G3DSA:2.40.160.20 181 370 7.7E-9 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS05365 5426e046178e05594344e16811885b16 370 SUPERFAMILY SSF56925 186 370 1.54E-10 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS05365 5426e046178e05594344e16811885b16 370 Pfam PF13505 Outer membrane protein beta-barrel domain 179 370 2.7E-11 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel MED134_RS08555 f18f0ff96efc6c91939b17c79f2dbe16 144 Pfam PF07681 DoxX 12 90 8.4E-10 T 22-04-2016 IPR032808 DoxX family MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 Gene3D G3DSA:1.10.132.20 69 185 1.4E-37 T 22-04-2016 IPR023584 Ribosome recycling factor domain MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 PANTHER PTHR20982 3 185 1.7E-64 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 6 185 24.588 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 SUPERFAMILY SSF55194 6 184 8.5E-64 T 22-04-2016 IPR023584 Ribosome recycling factor domain MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 Pfam PF01765 Ribosome recycling factor 25 183 1.1E-58 T 22-04-2016 IPR023584 Ribosome recycling factor domain MED134_RS06825 e898db1dc7931fbde6a19629976c0883 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 13 185 3.3E-61 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 MED134_RS08630 c8959c387434d32bac3bfd2afe5d3bd5 183 Pfam PF03653 Uncharacterised protein family (UPF0093) 1 148 3.1E-47 T 22-04-2016 IPR005265 Uncharacterised protein family UPF0093 MED134_RS08630 c8959c387434d32bac3bfd2afe5d3bd5 183 PANTHER PTHR40255 3 173 8.8E-41 T 22-04-2016 MED134_RS08630 c8959c387434d32bac3bfd2afe5d3bd5 183 PIRSF PIRSF004638 1 151 1.2E-45 T 22-04-2016 IPR005265 Uncharacterised protein family UPF0093 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 Pfam PF12345 Protein of unknown function (DUF3641) 216 349 2.9E-55 T 22-04-2016 IPR024521 Domain of unknown function DUF3641 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 Pfam PF04055 Radical SAM superfamily 59 196 2.4E-9 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 PANTHER PTHR11228:SF20 1 343 6.8E-113 T 22-04-2016 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 Gene3D G3DSA:3.20.20.70 50 348 8.3E-29 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 PANTHER PTHR11228 1 343 6.8E-113 T 22-04-2016 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 Pfam PF13353 4Fe-4S single cluster domain 64 161 3.5E-5 T 22-04-2016 MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 TIGRFAM TIGR04167 rSAM_SeCys: radical SAM/Cys-rich domain protein 48 349 3.2E-132 T 22-04-2016 IPR026351 Radical SAM/Cys-rich domain protein MED134_RS06530 db53bd4d53095fd415cd93973aa578e9 351 SUPERFAMILY SSF102114 55 346 8.63E-38 T 22-04-2016 MED134_RS09720 0b8072a99c5b7fe5fd658892a9c519a6 1133 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 1059 1132 9.1E-15 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS09720 0b8072a99c5b7fe5fd658892a9c519a6 1133 SUPERFAMILY SSF110296 446 739 6.19E-19 T 22-04-2016 MED134_RS09720 0b8072a99c5b7fe5fd658892a9c519a6 1133 SUPERFAMILY SSF110296 110 414 1.18E-55 T 22-04-2016 MED134_RS09720 0b8072a99c5b7fe5fd658892a9c519a6 1133 Gene3D G3DSA:2.130.10.140 488 738 2.2E-30 T 22-04-2016 MED134_RS09720 0b8072a99c5b7fe5fd658892a9c519a6 1133 Gene3D G3DSA:2.130.10.140 129 482 4.7E-86 T 22-04-2016 MED134_RS11425 74333247e1b89ef59ba12b4feba56830 67 SUPERFAMILY SSF89807 1 66 1.27E-19 T 22-04-2016 IPR009923 Dodecin MED134_RS11425 74333247e1b89ef59ba12b4feba56830 67 Pfam PF07311 Dodecin 3 66 1.8E-25 T 22-04-2016 IPR009923 Dodecin MED134_RS11425 74333247e1b89ef59ba12b4feba56830 67 Gene3D G3DSA:3.30.1660.10 2 66 5.4E-20 T 22-04-2016 IPR025543 Dodecin-like MED134_RS04300 82712e3fde52b725653b24b8d45ad02d 73 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 8 70 4.7E-34 T 22-04-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 MED134_RS04300 82712e3fde52b725653b24b8d45ad02d 73 Gene3D G3DSA:1.10.720.30 16 72 2.6E-30 T 22-04-2016 IPR003034 SAP domain MED134_RS07955 dfd160342642196b56bf0db2e150d710 158 Pfam PF11188 Protein of unknown function (DUF2975) 47 158 5.3E-6 T 22-04-2016 IPR021354 Protein of unknown function DUF2975 MED134_RS03395 7db32ad401ea0fb8763ccf49d319e16c 175 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 114 160 1.3E-6 T 22-04-2016 IPR018637 Domain of unknown function DUF2059 MED134_RS03395 7db32ad401ea0fb8763ccf49d319e16c 175 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 78 119 6.2E-7 T 22-04-2016 IPR018637 Domain of unknown function DUF2059 MED134_RS11495 b13f2a79db70d5155ee7275a7902f70d 94 Pfam PF06243 Phenylacetic acid degradation B 4 91 3.6E-39 T 22-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 MED134_RS11495 b13f2a79db70d5155ee7275a7902f70d 94 PIRSF PIRSF030200 1 94 1.3E-42 T 22-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 MED134_RS11495 b13f2a79db70d5155ee7275a7902f70d 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 5 94 1.1E-44 T 22-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 MED134_RS01590 15105c2f2a0505c9ce92f9c5d0395da8 180 Pfam PF04264 YceI-like domain 47 173 2.4E-9 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS01590 15105c2f2a0505c9ce92f9c5d0395da8 180 SUPERFAMILY SSF101874 27 177 1.57E-16 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS01590 15105c2f2a0505c9ce92f9c5d0395da8 180 Gene3D G3DSA:2.40.128.110 51 178 6.3E-17 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS14540 6756e59fbdc75725cc25f4f3054b25ab 173 SUPERFAMILY SSF109854 10 170 2.75E-25 T 22-04-2016 MED134_RS14540 6756e59fbdc75725cc25f4f3054b25ab 173 Pfam PF12867 DinB superfamily 40 167 1.6E-12 T 22-04-2016 IPR024775 DinB-like domain MED134_RS14540 6756e59fbdc75725cc25f4f3054b25ab 173 Gene3D G3DSA:1.20.120.450 11 173 1.4E-43 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 Gene3D G3DSA:2.120.10.30 570 638 5.8E-6 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 659 726 1.2E-5 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 SUPERFAMILY SSF63829 286 533 5.82E-10 T 22-04-2016 MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 SUPERFAMILY SSF63829 561 671 8.5E-6 T 22-04-2016 MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 Gene3D G3DSA:2.120.10.30 246 450 5.0E-4 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 Gene3D G3DSA:2.120.10.30 451 534 2.1E-4 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 SUPERFAMILY SSF50998 356 390 4.71E-6 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 SUPERFAMILY SSF50998 8 223 4.71E-6 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MED134_RS09810 b82ab119ef87a6627318115140e0996a 743 Pfam PF07494 Two component regulator propeller 513 533 0.0046 T 22-04-2016 IPR011110 Two component regulator propeller MED134_RS13550 c9bbda361ccf58f7e3276edcea1d79f0 342 Gene3D G3DSA:2.40.160.20 205 309 7.9E-4 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS13550 c9bbda361ccf58f7e3276edcea1d79f0 342 Gene3D G3DSA:2.40.160.60 18 72 2.7E-7 T 22-04-2016 MED134_RS13550 c9bbda361ccf58f7e3276edcea1d79f0 342 SUPERFAMILY SSF56935 15 249 2.87E-5 T 22-04-2016 MED134_RS10580 07501076d1528e8eb300d864b99d6423 173 Pfam PF11322 Protein of unknown function (DUF3124) 52 172 1.4E-46 T 22-04-2016 IPR021471 Protein of unknown function DUF3124 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 411 7.7E-102 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 PANTHER PTHR30474:SF1 254 415 3.6E-116 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 PANTHER PTHR30474:SF1 10 205 3.6E-116 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 Pfam PF01098 Cell cycle protein 237 412 6.7E-47 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 Pfam PF01098 Cell cycle protein 13 208 3.5E-30 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 PANTHER PTHR30474 254 415 3.6E-116 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS06250 e02b4e53d37ba91f33730bed5a059279 419 PANTHER PTHR30474 10 205 3.6E-116 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 MED134_RS07885 8169a40a5e8cff2418da0ce69f113899 193 Gene3D G3DSA:3.40.50.150 18 179 1.5E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS07885 8169a40a5e8cff2418da0ce69f113899 193 SUPERFAMILY SSF53335 3 192 2.05E-47 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS07885 8169a40a5e8cff2418da0ce69f113899 193 PANTHER PTHR32183:SF6 8 172 3.5E-22 T 22-04-2016 MED134_RS07885 8169a40a5e8cff2418da0ce69f113899 193 PANTHER PTHR32183 8 172 3.5E-22 T 22-04-2016 MED134_RS07885 8169a40a5e8cff2418da0ce69f113899 193 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 5 175 4.6E-29 T 22-04-2016 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67 MED134_RS03310 b771855b80373ec37a871a945bf7f4d2 242 Pfam PF11750 Protein of unknown function (DUF3307) 7 121 2.0E-22 T 22-04-2016 IPR021737 Bacteriophage phiKZ, Orf197 MED134_RS08245 36f1f334f4c1ca446d1ae56ae8470096 128 Gene3D G3DSA:2.60.120.10 1 114 9.2E-32 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS08245 36f1f334f4c1ca446d1ae56ae8470096 128 SUPERFAMILY SSF51182 1 116 8.25E-22 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS08245 36f1f334f4c1ca446d1ae56ae8470096 128 Pfam PF07883 Cupin domain 37 104 6.9E-10 T 22-04-2016 IPR013096 Cupin 2, conserved barrel MED134_RS07320 051f78a6afe358c49f847daef32a050a 318 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 11 305 5.4E-80 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS07320 051f78a6afe358c49f847daef32a050a 318 Pfam PF11751 Protein of unknown function (DUF3308) 24 303 5.1E-92 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS07340 051f78a6afe358c49f847daef32a050a 318 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 11 305 5.4E-80 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS07340 051f78a6afe358c49f847daef32a050a 318 Pfam PF11751 Protein of unknown function (DUF3308) 24 303 5.1E-92 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS01940 de1ec5809bffa348b2f100ed417c25b5 944 Gene3D G3DSA:1.10.390.10 346 492 1.6E-8 T 22-04-2016 MED134_RS01940 de1ec5809bffa348b2f100ed417c25b5 944 SUPERFAMILY SSF55486 275 490 1.39E-8 T 22-04-2016 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 SUPERFAMILY SSF161098 128 342 5.76E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 PANTHER PTHR30465 5 76 7.3E-94 T 22-04-2016 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 PANTHER PTHR30465 113 357 7.3E-94 T 22-04-2016 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 356 8.0E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 Gene3D G3DSA:1.10.3720.10 125 353 8.9E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 PANTHER PTHR30465:SF0 113 357 7.3E-94 T 22-04-2016 MED134_RS13525 73061c163e3bb38de31d70ace3537509 358 PANTHER PTHR30465:SF0 5 76 7.3E-94 T 22-04-2016 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 265 6.1E-50 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 237 6.6E-24 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 7 18 - T 22-04-2016 IPR000150 Cof protein GO:0016787 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 PANTHER PTHR10000 1 271 7.4E-50 T 22-04-2016 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 Gene3D G3DSA:3.30.1240.10 87 182 5.6E-19 T 22-04-2016 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 265 5.1E-46 T 22-04-2016 IPR000150 Cof protein GO:0016787 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 SUPERFAMILY SSF56784 3 269 4.02E-58 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 PANTHER PTHR10000:SF8 1 271 7.4E-50 T 22-04-2016 MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 Gene3D G3DSA:3.40.50.1000 2 73 2.9E-41 T 22-04-2016 IPR023214 HAD-like domain MED134_RS13300 dd6dfd25f00693d787fc39fa3bb974bb 272 Gene3D G3DSA:3.40.50.1000 183 270 2.9E-41 T 22-04-2016 IPR023214 HAD-like domain MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 SUPERFAMILY SSF54631 219 348 4.42E-23 T 22-04-2016 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 Gene3D G3DSA:3.10.580.10 210 331 3.8E-11 T 22-04-2016 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 Pfam PF01595 Domain of unknown function DUF21 9 198 1.6E-33 T 22-04-2016 IPR002550 Domain of unknown function DUF21 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 Gene3D G3DSA:3.30.465.10 332 429 7.1E-23 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 PANTHER PTHR22777 15 428 1.7E-91 T 22-04-2016 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 Pfam PF03471 Transporter associated domain 354 429 4.0E-17 T 22-04-2016 IPR005170 Transporter-associated domain MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 SMART SM01091 352 431 3.9E-20 T 22-04-2016 IPR005170 Transporter-associated domain MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 SMART SM00116 289 337 0.061 T 22-04-2016 IPR000644 CBS domain MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 SMART SM00116 232 281 23.0 T 22-04-2016 IPR000644 CBS domain MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 SUPERFAMILY SSF56176 353 428 4.09E-17 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MED134_RS06485 5f7c991f7ea962974abcab5908862960 432 Pfam PF00571 CBS domain 288 336 3.0E-5 T 22-04-2016 IPR000644 CBS domain MED134_RS06455 c15294f276d09244e773d944f9be99a1 179 SUPERFAMILY SSF52833 18 159 1.44E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06455 c15294f276d09244e773d944f9be99a1 179 Pfam PF13899 Thioredoxin-like 23 127 4.9E-12 T 22-04-2016 MED134_RS06455 c15294f276d09244e773d944f9be99a1 179 Gene3D G3DSA:3.40.30.10 20 145 6.1E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06455 c15294f276d09244e773d944f9be99a1 179 ProSitePatterns PS00194 Thioredoxin family active site. 41 59 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 MED134_RS04220 2758e4dbc03ac1550643eb12909e4fe7 244 SUPERFAMILY SSF49464 30 105 1.96E-7 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS04220 2758e4dbc03ac1550643eb12909e4fe7 244 Gene3D G3DSA:2.60.40.1120 35 113 5.7E-5 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 PANTHER PTHR35089 1 170 7.0E-20 T 22-04-2016 MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 Pfam PF03938 Outer membrane protein (OmpH-like) 8 163 3.4E-27 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 SMART SM00935 7 164 2.6E-32 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 SUPERFAMILY SSF111384 19 164 3.53E-20 T 22-04-2016 IPR024930 Skp domain MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 Gene3D G3DSA:3.30.910.20 93 164 3.2E-16 T 22-04-2016 MED134_RS09185 b8bdd80e988320919fa36da1195fed5a 171 Gene3D G3DSA:3.30.910.20 8 55 3.2E-16 T 22-04-2016 MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 PANTHER PTHR10366 3 309 1.7E-122 T 22-04-2016 MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 PANTHER PTHR10366:SF399 3 309 1.7E-122 T 22-04-2016 MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 Gene3D G3DSA:3.90.25.10 172 311 1.1E-50 T 22-04-2016 MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 Gene3D G3DSA:3.40.50.720 1 171 1.3E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 SUPERFAMILY SSF51735 1 310 1.03E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS09290 5cc91aa12968c510bb4f997a0b58e8cc 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 302 2.7E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS14555 4a8ce9e8b535eab05e749c141fce261d 194 Gene3D G3DSA:3.10.450.50 22 130 5.9E-6 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS14555 4a8ce9e8b535eab05e749c141fce261d 194 SUPERFAMILY SSF54427 20 129 9.45E-6 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS02935 d2de23af0338fce749212f597286cdbb 839 SUPERFAMILY SSF53187 49 364 2.13E-58 T 22-04-2016 MED134_RS02935 d2de23af0338fce749212f597286cdbb 839 SUPERFAMILY SSF52317 606 835 1.28E-14 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02935 d2de23af0338fce749212f597286cdbb 839 Gene3D G3DSA:3.40.630.10 53 319 5.1E-37 T 22-04-2016 MED134_RS02935 d2de23af0338fce749212f597286cdbb 839 SMART SM00631 55 340 0.0052 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS02935 d2de23af0338fce749212f597286cdbb 839 Pfam PF00246 Zinc carboxypeptidase 62 291 7.8E-24 T 22-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MED134_RS12970 0c56cc449a94ae3477f0c251c580c423 220 Gene3D G3DSA:3.40.470.10 43 186 4.4E-4 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like MED134_RS10545 f2d3b915c621929407bc835753e896f6 331 PANTHER PTHR30289 212 315 2.2E-13 T 22-04-2016 MED134_RS10545 f2d3b915c621929407bc835753e896f6 331 PANTHER PTHR30289:SF1 212 315 2.2E-13 T 22-04-2016 MED134_RS10545 f2d3b915c621929407bc835753e896f6 331 Pfam PF14240 YHYH protein 179 287 1.6E-9 T 22-04-2016 IPR025924 YHYH domain MED134_RS02430 532193fe843a5dabe0266bd448369987 193 Pfam PF00117 Glutamine amidotransferase class-I 5 191 6.5E-15 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 MED134_RS02430 532193fe843a5dabe0266bd448369987 193 PIRSF PIRSF000495 1 193 2.1E-62 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 MED134_RS02430 532193fe843a5dabe0266bd448369987 193 PANTHER PTHR21235:SF1 3 192 3.7E-73 T 22-04-2016 MED134_RS02430 532193fe843a5dabe0266bd448369987 193 SUPERFAMILY SSF52317 3 192 7.05E-47 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02430 532193fe843a5dabe0266bd448369987 193 Gene3D G3DSA:3.40.50.880 1 193 4.1E-66 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like MED134_RS02430 532193fe843a5dabe0266bd448369987 193 PANTHER PTHR21235 3 192 3.7E-73 T 22-04-2016 MED134_RS02430 532193fe843a5dabe0266bd448369987 193 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 193 31.958 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 MED134_RS02430 532193fe843a5dabe0266bd448369987 193 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 192 5.1E-61 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 24 252 1.2E-8 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 SUPERFAMILY SSF56300 140 170 3.14E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 SUPERFAMILY SSF56300 209 282 3.14E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 SUPERFAMILY SSF56300 24 109 3.14E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 Gene3D G3DSA:3.60.21.10 24 170 5.3E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS10810 ab897b876ba806fc39b6936e997184ac 297 Gene3D G3DSA:3.60.21.10 209 260 5.3E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14310 42a3c3379448217c4469bfcbb342dbbd 1225 Gene3D G3DSA:3.60.21.10 47 238 1.0E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14310 42a3c3379448217c4469bfcbb342dbbd 1225 Gene3D G3DSA:3.60.21.10 281 375 1.0E-20 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14310 42a3c3379448217c4469bfcbb342dbbd 1225 SUPERFAMILY SSF56300 81 238 7.17E-17 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS14310 42a3c3379448217c4469bfcbb342dbbd 1225 SUPERFAMILY SSF56300 290 363 7.17E-17 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like MED134_RS11780 24d681485e2c8f09b05a3c11f7e300fc 93 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 33 92 6.5E-18 T 22-04-2016 IPR018691 Protein of unknown function DUF2188 MED134_RS07460 b92f1aa32c438985ed45f104bcf0c038 503 PANTHER PTHR31901 5 500 4.3E-70 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS07460 b92f1aa32c438985ed45f104bcf0c038 503 Pfam PF03321 GH3 auxin-responsive promoter 21 493 4.5E-113 T 22-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- MED134_RS07460 b92f1aa32c438985ed45f104bcf0c038 503 PANTHER PTHR31901:SF5 5 500 4.3E-70 T 22-04-2016 MED134_RS09105 30451466a0d0d67ff79242d0004d9250 233 PANTHER PTHR30086 1 210 1.4E-15 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS09105 30451466a0d0d67ff79242d0004d9250 233 Pfam PF01810 LysE type translocator 14 205 4.1E-18 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS11735 d0409575585fdae956809949ae1b0ebf 204 SUPERFAMILY SSF55729 1 132 2.7E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS11735 d0409575585fdae956809949ae1b0ebf 204 Gene3D G3DSA:3.40.630.30 1 147 8.0E-14 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS10400 afb166e294a93f4ffb19eb58ac5d229d 125 Gene3D G3DSA:3.10.180.10 1 110 7.3E-19 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS10400 afb166e294a93f4ffb19eb58ac5d229d 125 SUPERFAMILY SSF54593 1 111 6.58E-23 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS10400 afb166e294a93f4ffb19eb58ac5d229d 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 108 4.0E-6 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS06790 bd946d2cc2cda23692627778211a617d 886 SUPERFAMILY SSF49344 32 224 9.02E-42 T 22-04-2016 MED134_RS06790 bd946d2cc2cda23692627778211a617d 886 Gene3D G3DSA:2.60.40.1190 32 210 5.4E-28 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS06790 bd946d2cc2cda23692627778211a617d 886 Pfam PF06452 Carbohydrate family 9 binding domain-like 39 190 1.7E-9 T 22-04-2016 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6784 MED134_RS07405 ffc44edfb2950ef41309e57fcd0fc4a4 475 Pfam PF08757 CotH protein 129 467 3.3E-45 T 22-04-2016 IPR014867 Spore coat protein CotH MED134_RS06960 22a44c6a57066fe641112a2a16eae1f8 153 SUPERFAMILY SSF56784 5 113 1.94E-27 T 22-04-2016 IPR023214 HAD-like domain MED134_RS06960 22a44c6a57066fe641112a2a16eae1f8 153 Gene3D G3DSA:3.40.50.1000 4 121 4.2E-45 T 22-04-2016 IPR023214 HAD-like domain MED134_RS06960 22a44c6a57066fe641112a2a16eae1f8 153 PIRSF PIRSF020079 5 140 3.6E-45 T 22-04-2016 IPR016769 Bacteriophage SP01, Orf1 MED134_RS10320 3d6df899cc0157ea19c047bbcd722adf 313 TIGRFAM TIGR03519 T9SS_PorP_fam: type IX secretion system membrane protein, PorP/SprF family 8 299 1.9E-85 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS10320 3d6df899cc0157ea19c047bbcd722adf 313 Pfam PF11751 Protein of unknown function (DUF3308) 22 298 5.1E-97 T 22-04-2016 IPR019861 Type IX secretion system membrane protein, PorP/SprF family MED134_RS05930 b33fc5dba264ce134eb20de764adb101 232 Pfam PF13568 Outer membrane protein beta-barrel domain 30 208 2.0E-17 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 162 3.3E-45 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 Hamap MF_00984 Single-stranded DNA-binding protein. 5 113 29.409 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 SUPERFAMILY SSF50249 5 162 2.16E-48 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 Pfam PF00436 Single-strand binding protein family 5 109 1.5E-33 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 PANTHER PTHR10302:SF0 1 162 8.5E-37 T 22-04-2016 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 PIRSF PIRSF002070 1 160 9.6E-35 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 PANTHER PTHR10302 1 162 8.5E-37 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 MED134_RS10210 3401bdd0b2b3e4ff66a04ffcf4ebe264 162 Gene3D G3DSA:2.40.50.140 2 162 6.0E-46 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold MED134_RS14705 77b57856f1e947776e60cf05fab96c58 397 Pfam PF12412 Protein of unknown function (DUF3667) 64 108 1.2E-17 T 22-04-2016 IPR022134 Protein of unknown function DUF3667 MED134_RS13700 ecb16d70cfa687d70f18968cbd68273e 347 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 28 347 7.2E-79 T 22-04-2016 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 MED134_RS13700 ecb16d70cfa687d70f18968cbd68273e 347 SUPERFAMILY SSF56935 25 306 3.66E-7 T 22-04-2016 MED134_RS13000 415e2da60a43fdf616e87513b6c9aa9a 197 SMART SM00740 110 180 2.5 T 22-04-2016 IPR005543 PASTA domain MED134_RS13000 415e2da60a43fdf616e87513b6c9aa9a 197 SMART SM00740 40 108 0.002 T 22-04-2016 IPR005543 PASTA domain MED134_RS13000 415e2da60a43fdf616e87513b6c9aa9a 197 Pfam PF03793 PASTA domain 45 107 7.0E-10 T 22-04-2016 IPR005543 PASTA domain MED134_RS13000 415e2da60a43fdf616e87513b6c9aa9a 197 Pfam PF03793 PASTA domain 114 164 1.2E-4 T 22-04-2016 IPR005543 PASTA domain MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 SUPERFAMILY SSF88946 2 99 1.39E-24 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 Gene3D G3DSA:1.10.1740.10 2 100 1.0E-30 T 22-04-2016 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 PANTHER PTHR30173 1 175 7.7E-38 T 22-04-2016 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 Pfam PF08281 Sigma-70, region 4 119 170 7.5E-15 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 PANTHER PTHR30173:SF24 1 175 7.7E-38 T 22-04-2016 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 Gene3D G3DSA:1.10.10.10 115 174 6.3E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 74 - T 22-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 Pfam PF04542 Sigma-70 region 2 21 88 9.1E-15 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 172 2.2E-30 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS01865 686bc1151e719f25b178e9fb26ca2f27 177 SUPERFAMILY SSF88659 115 174 4.11E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MED134_RS06650 088734db5b82abfe301f417e01e93abe 236 Pfam PF04784 Protein of unknown function, DUF547 69 170 2.1E-19 T 22-04-2016 IPR006869 Domain of unknown function DUF547 MED134_RS06650 088734db5b82abfe301f417e01e93abe 236 PANTHER PTHR23054:SF14 40 236 3.4E-15 T 22-04-2016 MED134_RS06650 088734db5b82abfe301f417e01e93abe 236 PANTHER PTHR23054 40 236 3.4E-15 T 22-04-2016 MED134_RS07840 a18e693304f96c536566698eb99d2247 503 Gene3D G3DSA:2.60.40.1120 28 83 9.7E-5 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07840 a18e693304f96c536566698eb99d2247 503 SUPERFAMILY SSF49464 28 90 2.09E-6 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07840 a18e693304f96c536566698eb99d2247 503 Pfam PF13715 CarboxypepD_reg-like domain 28 107 8.2E-9 T 22-04-2016 MED134_RS04430 b17b5e37e284244285e3f3d84ce43839 241 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 41 225 1.6E-51 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS04430 b17b5e37e284244285e3f3d84ce43839 241 PANTHER PTHR39200:SF1 1 241 3.4E-38 T 22-04-2016 MED134_RS04430 b17b5e37e284244285e3f3d84ce43839 241 PANTHER PTHR39200 1 241 3.4E-38 T 22-04-2016 MED134_RS13070 433497fcdd7092fc52b1f576a09a00ba 167 Gene3D G3DSA:3.40.30.10 3 149 1.4E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS13070 433497fcdd7092fc52b1f576a09a00ba 167 SUPERFAMILY SSF52833 30 162 7.89E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS13070 433497fcdd7092fc52b1f576a09a00ba 167 Pfam PF00578 AhpC/TSA family 41 145 6.2E-15 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 MED134_RS05210 be065410deac918da83f9511bacd4679 112 Pfam PF01192 RNA polymerase Rpb6 22 73 2.6E-7 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS05210 be065410deac918da83f9511bacd4679 112 SMART SM01409 19 73 0.0015 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MED134_RS07375 5897d68b788c19b993e7fd2a77800899 440 Gene3D G3DSA:1.25.40.10 332 398 7.3E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07375 5897d68b788c19b993e7fd2a77800899 440 SUPERFAMILY SSF48452 42 440 1.26E-33 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS07375 5897d68b788c19b993e7fd2a77800899 440 Pfam PF07980 SusD family 338 419 4.7E-13 T 22-04-2016 IPR012944 RagB/SusD domain MED134_RS06935 568a909180fb2a45f4381ec24b7e4379 261 PANTHER PTHR22726:SF9 1 251 1.4E-71 T 22-04-2016 MED134_RS06935 568a909180fb2a45f4381ec24b7e4379 261 Gene3D G3DSA:3.30.2010.10 76 152 7.7E-15 T 22-04-2016 MED134_RS06935 568a909180fb2a45f4381ec24b7e4379 261 PANTHER PTHR22726 1 251 1.4E-71 T 22-04-2016 MED134_RS06935 568a909180fb2a45f4381ec24b7e4379 261 Pfam PF01435 Peptidase family M48 74 248 1.7E-29 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MED134_RS06950 1f74d3b6877bf63646878b93a17b223e 190 Gene3D G3DSA:3.40.30.10 58 180 7.5E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS06950 1f74d3b6877bf63646878b93a17b223e 190 Pfam PF14595 Thioredoxin 62 169 6.3E-8 T 22-04-2016 MED134_RS06950 1f74d3b6877bf63646878b93a17b223e 190 SUPERFAMILY SSF52833 74 178 3.66E-13 T 22-04-2016 IPR012336 Thioredoxin-like fold MED134_RS10670 11f596dab052373594557d5fb6cf79db 158 Pfam PF03073 TspO/MBR family 12 156 9.1E-44 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 MED134_RS10670 11f596dab052373594557d5fb6cf79db 158 PIRSF PIRSF005859 1 158 9.8E-49 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 MED134_RS10670 11f596dab052373594557d5fb6cf79db 158 PANTHER PTHR10057 9 158 1.8E-46 T 22-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 MED134_RS05800 6ba547ef860c89bc4c807dc65e023adf 248 Pfam PF10099 Anti-sigma-K factor rskA 59 230 1.8E-15 T 22-04-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 162 225 6.8E-11 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 32 104 4.4E-23 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 PANTHER PTHR30522 1 257 1.3E-109 T 22-04-2016 MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 PANTHER PTHR30522:SF0 1 257 1.3E-109 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 TIGRFAM TIGR00444 mazG: MazG family protein 24 256 5.9E-86 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 SUPERFAMILY SSF101386 136 234 2.43E-26 T 22-04-2016 MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 Gene3D G3DSA:1.10.287.1080 23 77 1.8E-8 T 22-04-2016 MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 Gene3D G3DSA:1.10.287.1080 132 221 9.6E-17 T 22-04-2016 MED134_RS04310 ffd036acc23f16be700b39210c252e58 258 SUPERFAMILY SSF101386 11 109 1.11E-20 T 22-04-2016 MED134_RS07660 dd41d69f678c313d5a9d49cb6b2b348b 451 PANTHER PTHR23408 186 413 6.5E-42 T 22-04-2016 MED134_RS07660 dd41d69f678c313d5a9d49cb6b2b348b 451 Pfam PF01642 Methylmalonyl-CoA mutase 138 418 7.0E-70 T 22-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 MED134_RS07660 dd41d69f678c313d5a9d49cb6b2b348b 451 Gene3D G3DSA:3.20.20.240 36 449 2.2E-85 T 22-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 MED134_RS07660 dd41d69f678c313d5a9d49cb6b2b348b 451 SUPERFAMILY SSF51703 3 412 6.54E-101 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 MED134_RS07660 dd41d69f678c313d5a9d49cb6b2b348b 451 PANTHER PTHR23408:SF13 186 413 6.5E-42 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.170.130.10 114 234 2.9E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.60.40.1120 29 113 3.3E-11 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.40.170.20 972 1012 8.7E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.40.170.20 596 627 8.7E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.40.170.20 669 913 8.7E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Gene3D G3DSA:2.40.170.20 235 523 8.7E-36 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069 1 547 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069 587 640 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069 659 1019 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 Pfam PF13620 Carboxypeptidase regulatory-like domain 27 105 2.5E-16 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069:SF6 1 547 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069:SF6 587 640 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 PANTHER PTHR30069:SF6 659 1019 2.1E-118 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 567 637 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 354 517 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 103 306 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 666 766 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 974 1012 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF56935 799 925 4.58E-55 T 22-04-2016 MED134_RS02195 724442e755c3ce8fc951d989919049e7 1072 SUPERFAMILY SSF49464 26 115 1.55E-14 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS08285 bb7b5ecc8c2ab1abb3776abf8d935e75 442 PANTHER PTHR12639 2 439 2.6E-61 T 22-04-2016 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90 MED134_RS08285 bb7b5ecc8c2ab1abb3776abf8d935e75 442 SMART SM00752 8 269 2.8E-26 T 22-04-2016 IPR011020 HTTM MED134_RS08285 bb7b5ecc8c2ab1abb3776abf8d935e75 442 Pfam PF05090 Vitamin K-dependent gamma-carboxylase 18 439 9.5E-151 T 22-04-2016 IPR007782 Vitamin K-dependent gamma-carboxylase GO:0008488|GO:0017187 KEGG: 00130+4.1.1.90 MED134_RS14620 1f5b0e5731474dab5541be95787c6240 334 Gene3D G3DSA:2.40.30.10 234 327 6.1E-14 T 22-04-2016 MED134_RS14620 1f5b0e5731474dab5541be95787c6240 334 SUPERFAMILY SSF50465 234 331 1.34E-13 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 PANTHER PTHR11603 1 334 2.8E-141 T 22-04-2016 MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 Gene3D G3DSA:3.40.50.300 36 200 1.4E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 54 184 1.2E-64 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 PIRSF PIRSF002849 1 334 1.1E-130 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 Gene3D G3DSA:1.10.8.300 214 330 4.7E-40 T 22-04-2016 MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 SUPERFAMILY SSF52540 32 310 6.5E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09960 834e5c528c28796e2a6c611d843bb683 334 PANTHER PTHR11603:SF148 1 334 2.8E-141 T 22-04-2016 MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SUPERFAMILY SSF51126 505 756 1.65E-34 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 265 291 350.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 243 264 5600.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 625 646 140.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 715 739 8000.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 330 357 6000.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SMART SM00710 687 712 2100.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 Pfam PF16318 Domain of unknown function (DUF4957) 530 640 3.9E-12 T 22-04-2016 IPR032530 Domain of unknown function DUF4957 MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 Pfam PF14592 Chondroitinase B 28 451 6.1E-208 T 22-04-2016 MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 SUPERFAMILY SSF51126 26 502 1.14E-106 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 Gene3D G3DSA:2.160.20.10 505 764 5.1E-32 T 22-04-2016 IPR012334 Pectin lyase fold MED134_RS10515 cbf28d20a7b0779275f3d53349f2da1c 767 Gene3D G3DSA:2.160.20.10 27 491 1.1E-114 T 22-04-2016 IPR012334 Pectin lyase fold MED134_RS04370 46252479e73e6384bae97d506af7a667 211 Pfam PF01841 Transglutaminase-like superfamily 29 135 9.8E-12 T 22-04-2016 IPR002931 Transglutaminase-like MED134_RS04370 46252479e73e6384bae97d506af7a667 211 SUPERFAMILY SSF54001 15 153 3.44E-18 T 22-04-2016 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 SMART SM00418 18 100 2.1E-14 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 PANTHER PTHR33154 21 108 5.5E-13 T 22-04-2016 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 Gene3D G3DSA:1.10.10.10 4 101 4.5E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 Pfam PF01022 Bacterial regulatory protein, arsR family 25 71 1.8E-12 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 4.8E-7 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.8E-7 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 4.8E-7 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MED134_RS10525 05a25d24c28c70f6ab86cccd6f396873 109 SUPERFAMILY SSF46785 10 100 5.06E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 Gene3D G3DSA:3.40.50.1820 261 435 5.1E-38 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 Gene3D G3DSA:3.40.50.1820 55 111 5.1E-38 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 Gene3D G3DSA:3.40.50.1820 156 200 5.1E-38 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 65 423 1.7E-23 T 22-04-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 PANTHER PTHR10272 1 419 5.8E-35 T 22-04-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 SUPERFAMILY SSF53474 145 196 8.8E-19 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS05025 86262fcd33af6cb3a1baadeb4b083fcd 439 SUPERFAMILY SSF53474 265 428 8.8E-19 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS14650 8abb0194ea95961cbba2b8049474787e 196 Pfam PF14302 Domain of unknown function (DUF4377) 60 116 1.5E-10 T 22-04-2016 IPR025485 Domain of unknown function DUF4377 MED134_RS08735 94aae5bd19e37d50181f68832a3d9e65 382 PANTHER PTHR22935 91 367 2.1E-43 T 22-04-2016 MED134_RS08735 94aae5bd19e37d50181f68832a3d9e65 382 PANTHER PTHR22935:SF2 91 367 2.1E-43 T 22-04-2016 MED134_RS08735 94aae5bd19e37d50181f68832a3d9e65 382 Pfam PF00144 Beta-lactamase 90 351 3.2E-32 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS08735 94aae5bd19e37d50181f68832a3d9e65 382 Gene3D G3DSA:3.40.710.10 88 363 2.2E-47 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS08735 94aae5bd19e37d50181f68832a3d9e65 382 SUPERFAMILY SSF56601 5 371 3.44E-74 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS03700 dfe0bfe55522141161e7dea5e68b876e 371 Pfam PF14072 DNA-sulfur modification-associated 11 324 6.7E-18 T 22-04-2016 IPR017642 DNA sulphur modification protein DndB MED134_RS03700 dfe0bfe55522141161e7dea5e68b876e 371 TIGRFAM TIGR03187 DGQHR: DGQHR domain 13 316 9.4E-72 T 22-04-2016 IPR017601 DGQHR-containing domain MED134_RS10780 2a0f86a28f9a37fdbd3e61e897b6bad3 209 Pfam PF01810 LysE type translocator 16 197 1.7E-11 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 MED134_RS08635 7608563bd5637328493226b5059224e3 222 Gene3D G3DSA:2.40.160.20 46 209 6.3E-16 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS08635 7608563bd5637328493226b5059224e3 222 SUPERFAMILY SSF56925 49 213 6.8E-15 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS08635 7608563bd5637328493226b5059224e3 222 Pfam PF13505 Outer membrane protein beta-barrel domain 12 213 1.4E-17 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel MED134_RS14105 a86b435d47e42d46321bdbf7488361b5 350 PANTHER PTHR35457 97 337 2.0E-29 T 22-04-2016 MED134_RS14105 a86b435d47e42d46321bdbf7488361b5 350 PANTHER PTHR35457 2 44 2.0E-29 T 22-04-2016 MED134_RS14105 a86b435d47e42d46321bdbf7488361b5 350 Pfam PF02628 Cytochrome oxidase assembly protein 7 331 2.1E-37 T 22-04-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 MED134_RS14105 a86b435d47e42d46321bdbf7488361b5 350 PANTHER PTHR35457:SF1 97 337 2.0E-29 T 22-04-2016 MED134_RS14105 a86b435d47e42d46321bdbf7488361b5 350 PANTHER PTHR35457:SF1 2 44 2.0E-29 T 22-04-2016 MED134_RS14515 89b214a92361bad7e3f261b52a64dd04 281 SUPERFAMILY SSF103473 9 259 5.36E-6 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS14515 89b214a92361bad7e3f261b52a64dd04 281 Pfam PF03741 Integral membrane protein TerC family 15 218 3.0E-50 T 22-04-2016 IPR005496 Integral membrane protein TerC GO:0016021 MED134_RS14515 89b214a92361bad7e3f261b52a64dd04 281 PANTHER PTHR30060:SF1 1 258 7.0E-87 T 22-04-2016 MED134_RS14515 89b214a92361bad7e3f261b52a64dd04 281 PANTHER PTHR30060 1 258 7.0E-87 T 22-04-2016 MED134_RS11210 5c44f0462f375befa15b989aa94e228c 232 PANTHER PTHR40394 26 227 1.2E-20 T 22-04-2016 MED134_RS11210 5c44f0462f375befa15b989aa94e228c 232 Gene3D G3DSA:1.10.760.10 86 181 6.0E-16 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS11210 5c44f0462f375befa15b989aa94e228c 232 SUPERFAMILY SSF46626 82 181 2.54E-16 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS11210 5c44f0462f375befa15b989aa94e228c 232 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 96 176 3.1E-10 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS05975 0954ce47614070ab45c8c256b2974867 145 Pfam PF13650 Aspartyl protease 29 127 1.2E-14 T 22-04-2016 MED134_RS05975 0954ce47614070ab45c8c256b2974867 145 SUPERFAMILY SSF50630 22 136 2.66E-10 T 22-04-2016 IPR021109 Aspartic peptidase domain MED134_RS05975 0954ce47614070ab45c8c256b2974867 145 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 39 50 - T 22-04-2016 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MED134_RS01610 aa451a15fe7641db05b2d513a06ab04b 186 Pfam PF14902 Domain of unknown function (DUF4494) 5 144 1.7E-46 T 22-04-2016 IPR027848 Protein of unknown function DUF4494 MED134_RS03305 a8bb4c0c843840bd4f088c8a029ed75e 230 Gene3D G3DSA:1.10.10.10 170 206 6.6E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS03305 a8bb4c0c843840bd4f088c8a029ed75e 230 SUPERFAMILY SSF46894 158 207 7.94E-5 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MED134_RS11920 d66e88b513c6e9540bb6935430e2b7cc 361 SUPERFAMILY SSF53448 6 282 7.93E-61 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11920 d66e88b513c6e9540bb6935430e2b7cc 361 SUPERFAMILY SSF159283 290 352 6.67E-12 T 22-04-2016 MED134_RS11920 d66e88b513c6e9540bb6935430e2b7cc 361 Gene3D G3DSA:3.90.550.10 5 274 7.8E-79 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11920 d66e88b513c6e9540bb6935430e2b7cc 361 Pfam PF00483 Nucleotidyl transferase 9 286 1.8E-46 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 MED134_RS11920 d66e88b513c6e9540bb6935430e2b7cc 361 PANTHER PTHR12526 158 288 7.3E-37 T 22-04-2016 MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 Gene3D G3DSA:2.60.120.10 2 180 5.0E-74 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 3.0E-70 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 PANTHER PTHR21047 2 179 1.1E-67 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 SUPERFAMILY SSF51182 2 181 1.01E-68 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 5 171 6.0E-48 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MED134_RS01350 c0cd66cb51ade1089546088d9595ef99 184 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 4.2E-70 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MED134_RS11105 2c59b0a75fec0051f226f5e10576b502 230 PANTHER PTHR10859 2 225 9.1E-45 T 22-04-2016 MED134_RS11105 2c59b0a75fec0051f226f5e10576b502 230 Gene3D G3DSA:3.90.550.10 1 123 1.1E-16 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11105 2c59b0a75fec0051f226f5e10576b502 230 SUPERFAMILY SSF53448 2 206 1.36E-33 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS11105 2c59b0a75fec0051f226f5e10576b502 230 Pfam PF00535 Glycosyl transferase family 2 7 137 1.1E-20 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS06665 e8d077644931d8936b142d4d50692cbe 609 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 248 488 7.0E-5 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 MED134_RS06665 e8d077644931d8936b142d4d50692cbe 609 SUPERFAMILY SSF53383 248 604 1.86E-12 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase MED134_RS06665 e8d077644931d8936b142d4d50692cbe 609 Gene3D G3DSA:3.40.640.10 248 452 5.1E-12 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MED134_RS05305 6eee5f7743ab1da1135e8d5a90c26382 598 PANTHER PTHR33885:SF3 71 204 6.2E-15 T 22-04-2016 MED134_RS05305 6eee5f7743ab1da1135e8d5a90c26382 598 PANTHER PTHR33885 71 204 6.2E-15 T 22-04-2016 MED134_RS05305 6eee5f7743ab1da1135e8d5a90c26382 598 Pfam PF04024 PspC domain 115 176 5.7E-19 T 22-04-2016 IPR007168 Phage shock protein, PspC, N-terminal MED134_RS03820 1cc78163c86c17758ee4b43784bce13a 508 Pfam PF07012 Curlin associated repeat 158 188 2.6E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03820 1cc78163c86c17758ee4b43784bce13a 508 Pfam PF07012 Curlin associated repeat 21 52 5.3E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 Gene3D G3DSA:3.50.50.60 291 348 2.5E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 Gene3D G3DSA:3.50.50.60 3 83 2.5E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 Gene3D G3DSA:3.50.50.60 132 191 2.5E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 Pfam PF01266 FAD dependent oxidoreductase 5 328 7.0E-19 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 SUPERFAMILY SSF51971 3 220 2.12E-14 T 22-04-2016 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 SUPERFAMILY SSF51971 276 333 2.12E-14 T 22-04-2016 MED134_RS06080 c6ee323d14efda7cc60cfc67bc4a19c4 352 Gene3D G3DSA:3.30.9.10 192 290 6.3E-8 T 22-04-2016 MED134_RS13460 126f290dcb63de7f427013bb2c32a6fe 369 PANTHER PTHR12526 201 369 1.8E-16 T 22-04-2016 MED134_RS13460 126f290dcb63de7f427013bb2c32a6fe 369 Pfam PF00534 Glycosyl transferases group 1 187 351 5.5E-19 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 MED134_RS13460 126f290dcb63de7f427013bb2c32a6fe 369 Gene3D G3DSA:3.40.50.2000 199 349 4.1E-11 T 22-04-2016 MED134_RS13460 126f290dcb63de7f427013bb2c32a6fe 369 SUPERFAMILY SSF53756 37 368 1.26E-34 T 22-04-2016 MED134_RS13460 126f290dcb63de7f427013bb2c32a6fe 369 PANTHER PTHR12526:SF397 201 369 1.8E-16 T 22-04-2016 MED134_RS03465 59708c705e50c518964c27474f6ae904 180 Pfam PF13858 Protein of unknown function (DUF4199) 17 173 2.6E-29 T 22-04-2016 IPR025250 Protein of unknown function DUF4199 MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 Gene3D G3DSA:3.90.870.10 2 204 1.6E-57 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 PANTHER PTHR17490:SF7 1 201 1.7E-70 T 22-04-2016 MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 Pfam PF01300 Telomere recombination 23 199 8.0E-45 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 PANTHER PTHR17490 1 201 1.7E-70 T 22-04-2016 MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 202 1.0E-57 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 MED134_RS03655 f866c28371a901b05dee3a986d1ae63b 205 SUPERFAMILY SSF55821 1 204 6.71E-51 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain MED134_RS03885 20e378d3599ce508a2ebf2497599b158 218 SUPERFAMILY SSF53474 21 215 1.49E-17 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03885 20e378d3599ce508a2ebf2497599b158 218 Pfam PF02230 Phospholipase/Carboxylesterase 22 215 1.7E-7 T 22-04-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MED134_RS03885 20e378d3599ce508a2ebf2497599b158 218 Gene3D G3DSA:3.40.50.1820 14 214 1.2E-15 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 Gene3D G3DSA:3.30.1330.10 34 176 2.2E-15 T 22-04-2016 IPR016188 PurM-like, N-terminal domain MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 Pfam PF02769 AIR synthase related protein, C-terminal domain 183 378 3.0E-7 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 Gene3D G3DSA:3.90.650.10 177 380 5.1E-41 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 SUPERFAMILY SSF55326 21 168 2.27E-13 T 22-04-2016 MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 SUPERFAMILY SSF56042 177 379 4.77E-31 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 PANTHER PTHR10520 37 237 1.2E-44 T 22-04-2016 MED134_RS03770 43549b71412b1239751f2bbd7be07898 393 PANTHER PTHR10520 253 377 1.2E-44 T 22-04-2016 MED134_RS11290 9134c301ba054499432bf4f217c7566a 242 SUPERFAMILY SSF74653 142 241 7.85E-8 T 22-04-2016 MED134_RS11290 9134c301ba054499432bf4f217c7566a 242 SUPERFAMILY SSF74653 67 80 7.85E-8 T 22-04-2016 MED134_RS11290 9134c301ba054499432bf4f217c7566a 242 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 180 239 1.5E-9 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 MED134_RS09790 ad0e19e421c168873b847647f48b2e7e 417 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 347 417 3.1E-16 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS14180 693d42c1efc9b21ffde61ad5bd78a091 404 Pfam PF16148 Domain of unknown function (DUF4856) 38 398 4.6E-154 T 22-04-2016 IPR032331 Protein of unknown function DUF4856 MED134_RS01620 1f0ab88477a297277cf3a240d6a49ffa 158 Gene3D G3DSA:2.60.120.10 32 147 3.3E-17 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS01620 1f0ab88477a297277cf3a240d6a49ffa 158 SUPERFAMILY SSF51182 34 148 8.9E-19 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS01620 1f0ab88477a297277cf3a240d6a49ffa 158 PANTHER PTHR33570 29 151 3.5E-12 T 22-04-2016 MED134_RS01620 1f0ab88477a297277cf3a240d6a49ffa 158 PANTHER PTHR33570:SF5 29 151 3.5E-12 T 22-04-2016 MED134_RS01620 1f0ab88477a297277cf3a240d6a49ffa 158 Pfam PF07883 Cupin domain 67 130 4.3E-8 T 22-04-2016 IPR013096 Cupin 2, conserved barrel MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 SUPERFAMILY SSF63411 23 233 2.44E-57 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 PANTHER PTHR11851:SF136 18 429 3.9E-120 T 22-04-2016 MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 Gene3D G3DSA:3.30.830.10 26 237 6.2E-53 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 PANTHER PTHR11851 18 429 3.9E-120 T 22-04-2016 MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 Pfam PF05193 Peptidase M16 inactive domain 190 366 4.8E-25 T 22-04-2016 IPR007863 Peptidase M16, C-terminal MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 Pfam PF00675 Insulinase (Peptidase family M16) 36 150 7.9E-19 T 22-04-2016 IPR011765 Peptidase M16, N-terminal MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 Gene3D G3DSA:3.30.830.10 257 428 8.0E-21 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 MED134_RS01275 7c2f6239f2e2543f5c15469bf4f91030 439 SUPERFAMILY SSF63411 255 436 2.07E-33 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 SUPERFAMILY SSF69318 454 516 1.96E-72 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 SUPERFAMILY SSF69318 57 419 1.96E-72 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 78 141 2.5E-14 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 720 788 2.7E-10 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 459 504 1.4E-6 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 838 897 1.4E-6 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 268 331 1.5E-12 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 SUPERFAMILY SSF69318 639 904 8.89E-57 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 SUPERFAMILY SSF69318 444 527 8.89E-57 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 PANTHER PTHR16026 372 450 5.6E-34 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 PANTHER PTHR16026 467 604 5.6E-34 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 PANTHER PTHR16026 70 346 5.6E-34 T 22-04-2016 IPR027039 Cartilage acidic protein 1 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Pfam PF07593 ASPIC and UnbV 540 607 1.3E-20 T 22-04-2016 IPR011519 ASPIC/UnbV MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 SUPERFAMILY SSF69318 990 1079 3.14E-7 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Gene3D G3DSA:2.130.10.130 889 1067 1.9E-8 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Gene3D G3DSA:2.130.10.130 459 521 1.0E-42 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Gene3D G3DSA:2.130.10.130 659 888 4.3E-23 T 22-04-2016 MED134_RS10640 a27ba179ae7c49226784c6ed269f599b 1113 Gene3D G3DSA:2.130.10.130 61 418 1.0E-42 T 22-04-2016 MED134_RS02655 7ec4b47dace565fefaee740b5a932433 161 Pfam PF13648 Lipocalin-like domain 32 118 8.4E-10 T 22-04-2016 IPR024311 Lipocalin-like domain MED134_RS09135 2c545977f0da09c3844be8f44233ffe8 139 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 11 103 7.4E-7 T 22-04-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 SUPERFAMILY SSF50939 485 741 5.1E-43 T 22-04-2016 IPR011040 Sialidases MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 Gene3D G3DSA:2.130.10.140 486 668 1.2E-30 T 22-04-2016 MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 Gene3D G3DSA:2.130.10.140 669 705 2.3E-4 T 22-04-2016 MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 Gene3D G3DSA:2.130.10.140 46 417 1.7E-83 T 22-04-2016 MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 SUPERFAMILY SSF110296 38 140 6.8E-17 T 22-04-2016 MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 Pfam PF15902 Sortilin, neurotensin receptor 3, 125 278 7.1E-12 T 22-04-2016 IPR031778 Sortilin, N-terminal MED134_RS02830 d6fbf7f3cca0ca53e25b54aab3014930 1028 SUPERFAMILY SSF110296 105 418 3.14E-58 T 22-04-2016 MED134_RS10620 af693de52229b0f7596753aabc6db174 189 PANTHER PTHR14136 6 170 1.5E-21 T 22-04-2016 MED134_RS10620 af693de52229b0f7596753aabc6db174 189 PANTHER PTHR14136:SF12 6 170 1.5E-21 T 22-04-2016 MED134_RS10620 af693de52229b0f7596753aabc6db174 189 Pfam PF13599 Pentapeptide repeats (9 copies) 27 85 3.8E-11 T 22-04-2016 IPR001646 Pentapeptide repeat MED134_RS10620 af693de52229b0f7596753aabc6db174 189 Pfam PF13599 Pentapeptide repeats (9 copies) 90 152 5.4E-11 T 22-04-2016 IPR001646 Pentapeptide repeat MED134_RS10620 af693de52229b0f7596753aabc6db174 189 SUPERFAMILY SSF141571 9 188 6.77E-43 T 22-04-2016 MED134_RS12975 cd8b711672e0d3ac2ea22fb1ddf1b706 39 TIGRFAM TIGR04560 ribo_THX: ribosomal small subunit protein bTHX 1 25 6.5E-12 T 22-04-2016 IPR030826 30S ribosomal protein GO:0005840 MED134_RS13340 f820cd145f7a71f307834dc64edca714 261 Pfam PF02563 Polysaccharide biosynthesis/export protein 43 139 9.6E-16 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MED134_RS13340 f820cd145f7a71f307834dc64edca714 261 Gene3D G3DSA:3.10.560.10 129 225 2.1E-13 T 22-04-2016 MED134_RS13340 f820cd145f7a71f307834dc64edca714 261 PANTHER PTHR33619 89 234 3.5E-31 T 22-04-2016 MED134_RS13340 f820cd145f7a71f307834dc64edca714 261 PANTHER PTHR33619 48 68 3.5E-31 T 22-04-2016 MED134_RS13340 f820cd145f7a71f307834dc64edca714 261 Gene3D G3DSA:3.30.1950.10 52 128 4.4E-11 T 22-04-2016 MED134_RS05400 992da1a34907450629f38f5185948e98 343 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 103 331 2.2E-18 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS05400 992da1a34907450629f38f5185948e98 343 SUPERFAMILY SSF56219 99 338 1.15E-32 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS05400 992da1a34907450629f38f5185948e98 343 Gene3D G3DSA:3.60.10.10 101 339 2.7E-15 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 SUPERFAMILY SSF48452 210 338 2.73E-8 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 SMART SM00342 499 586 1.0E-9 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 SUPERFAMILY SSF46689 552 588 1.17E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 Gene3D G3DSA:1.25.40.10 74 193 5.6E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 Gene3D G3DSA:1.25.40.10 206 358 3.9E-4 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 Gene3D G3DSA:1.10.10.60 552 581 2.4E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 MED134_RS02540 7740cab5fb17b7903f602bedc39b2962 615 Pfam PF12833 Helix-turn-helix domain 505 586 1.1E-11 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MED134_RS13960 bd453fc0070f98ae726817b7d90a0139 507 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 287 479 6.2E-10 T 22-04-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MED134_RS13960 bd453fc0070f98ae726817b7d90a0139 507 SUPERFAMILY SSF56935 35 139 1.72E-16 T 22-04-2016 MED134_RS13960 bd453fc0070f98ae726817b7d90a0139 507 SUPERFAMILY SSF56935 221 486 1.72E-16 T 22-04-2016 MED134_RS13960 bd453fc0070f98ae726817b7d90a0139 507 Gene3D G3DSA:2.40.160.60 217 506 3.3E-55 T 22-04-2016 MED134_RS13960 bd453fc0070f98ae726817b7d90a0139 507 Gene3D G3DSA:2.40.160.60 32 156 3.3E-55 T 22-04-2016 MED134_RS03400 9cbffc6a189d14a6d2e2f01c3d527648 257 Gene3D G3DSA:3.40.390.10 124 243 5.5E-5 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS03400 9cbffc6a189d14a6d2e2f01c3d527648 257 SUPERFAMILY SSF55486 118 227 5.57E-8 T 22-04-2016 MED134_RS06545 7940063db3b5d0b1c9d77b68221ab79f 479 PANTHER PTHR35148 1 479 4.4E-47 T 22-04-2016 MED134_RS06545 7940063db3b5d0b1c9d77b68221ab79f 479 Pfam PF12771 Starch-binding associating with outer membrane 11 476 1.4E-59 T 22-04-2016 MED134_RS06545 7940063db3b5d0b1c9d77b68221ab79f 479 SUPERFAMILY SSF48452 19 478 5.56E-114 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS14700 c9dde64b353ec322c6a4d7991eb52926 365 PANTHER PTHR23028 1 349 6.1E-22 T 22-04-2016 MED134_RS14700 c9dde64b353ec322c6a4d7991eb52926 365 Pfam PF01757 Acyltransferase family 1 339 2.6E-21 T 22-04-2016 IPR002656 Acyltransferase 3 GO:0016747 MED134_RS10240 8c55f001e6a855d03db5d92831d89ae3 159 PANTHER PTHR33602 20 157 3.7E-19 T 22-04-2016 MED134_RS10240 8c55f001e6a855d03db5d92831d89ae3 159 Gene3D G3DSA:1.10.10.10 59 103 2.4E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10240 8c55f001e6a855d03db5d92831d89ae3 159 Pfam PF02631 RecX family 42 154 4.1E-22 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 MED134_RS10240 8c55f001e6a855d03db5d92831d89ae3 159 Hamap MF_01114 Regulatory protein RecX [recX]. 2 157 11.545 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 MED134_RS10240 8c55f001e6a855d03db5d92831d89ae3 159 PANTHER PTHR33602:SF1 20 157 3.7E-19 T 22-04-2016 MED134_RS10745 6e49c0ff18bd6626132420e1054960dd 149 Pfam PF04945 YHS domain 45 81 1.1E-8 T 22-04-2016 IPR007029 YHS domain MED134_RS09520 f5bfe3e5772bacc42653bd312b28ffe7 114 Gene3D G3DSA:3.20.160.10 1 114 3.2E-52 T 22-04-2016 MED134_RS09520 f5bfe3e5772bacc42653bd312b28ffe7 114 Pfam PF08888 HopJ type III effector protein 3 111 2.1E-50 T 22-04-2016 IPR014984 HopJ type III effector protein MED134_RS10535 87b68899bbc2606da5404ba2dd268f65 210 PANTHER PTHR11717:SF18 24 106 8.0E-17 T 22-04-2016 MED134_RS10535 87b68899bbc2606da5404ba2dd268f65 210 PANTHER PTHR11717 24 106 8.0E-17 T 22-04-2016 MED134_RS10535 87b68899bbc2606da5404ba2dd268f65 210 Gene3D G3DSA:3.40.50.270 48 205 4.7E-22 T 22-04-2016 MED134_RS10535 87b68899bbc2606da5404ba2dd268f65 210 SUPERFAMILY SSF52788 49 207 4.71E-22 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 Gene3D G3DSA:3.40.710.10 184 486 1.3E-70 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 SUPERFAMILY SSF54427 41 153 3.18E-8 T 22-04-2016 IPR032710 NTF2-like domain MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 PANTHER PTHR22935 184 500 5.5E-51 T 22-04-2016 MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 Pfam PF00144 Beta-lactamase 184 478 8.2E-47 T 22-04-2016 IPR001466 Beta-lactamase-related MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 SUPERFAMILY SSF56601 184 480 4.35E-65 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like MED134_RS04015 fd8acd0f70a12c2ac6f281f2b356a775 503 Pfam PF14534 Domain of unknown function (DUF4440) 41 153 1.2E-10 T 22-04-2016 IPR027843 Domain of unknown function DUF4440 MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 SUPERFAMILY SSF53448 3 144 1.06E-21 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 PANTHER PTHR10859:SF99 5 127 1.1E-17 T 22-04-2016 MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 Gene3D G3DSA:3.90.550.10 4 111 1.4E-12 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 Gene3D G3DSA:3.90.550.10 157 219 1.4E-12 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 Pfam PF00535 Glycosyl transferase family 2 2 138 3.7E-19 T 22-04-2016 IPR001173 Glycosyltransferase 2-like MED134_RS04340 7ca0d882216bb076af66ecb53145305f 252 PANTHER PTHR10859 5 127 1.1E-17 T 22-04-2016 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 PANTHER PTHR12715:SF14 7 290 4.3E-54 T 22-04-2016 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 SUPERFAMILY SSF103481 42 143 2.35E-16 T 22-04-2016 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 Pfam PF00892 EamA-like transporter family 155 289 1.1E-10 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 Pfam PF00892 EamA-like transporter family 7 139 1.9E-22 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 PANTHER PTHR12715 7 290 4.3E-54 T 22-04-2016 MED134_RS09770 60757f6836b9626391cf0dbcf2811729 297 SUPERFAMILY SSF103481 188 293 2.09E-10 T 22-04-2016 MED134_RS11850 0cf1069d84b82b25f8dd3d43003ac89f 174 Pfam PF02517 CAAX protease self-immunity 4 160 4.7E-14 T 22-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 MED134_RS11665 e68ccc8d5fb0dcc129dae781b13db209 818 SUPERFAMILY SSF50998 741 786 3.84E-5 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MED134_RS11665 e68ccc8d5fb0dcc129dae781b13db209 818 SUPERFAMILY SSF50998 506 677 3.84E-5 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MED134_RS06585 11018aed7efbc43657682fc7029aadd6 322 Pfam PF08241 Methyltransferase domain 64 172 1.7E-16 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MED134_RS06585 11018aed7efbc43657682fc7029aadd6 322 PANTHER PTHR10108 1 271 1.4E-77 T 22-04-2016 MED134_RS06585 11018aed7efbc43657682fc7029aadd6 322 PANTHER PTHR10108:SF846 1 271 1.4E-77 T 22-04-2016 MED134_RS06585 11018aed7efbc43657682fc7029aadd6 322 Gene3D G3DSA:3.40.50.150 57 222 3.8E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS06585 11018aed7efbc43657682fc7029aadd6 322 SUPERFAMILY SSF53335 55 224 6.46E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13365 50c6d37dda7fb8f382f783b540915e3b 294 Pfam PF05050 Methyltransferase FkbM domain 109 275 1.2E-14 T 22-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- MED134_RS13365 50c6d37dda7fb8f382f783b540915e3b 294 SUPERFAMILY SSF53335 29 277 3.29E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS13365 50c6d37dda7fb8f382f783b540915e3b 294 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 106 258 3.3E-24 T 22-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- MED134_RS13365 50c6d37dda7fb8f382f783b540915e3b 294 Gene3D G3DSA:3.40.50.150 104 269 4.9E-18 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS08025 c0e63f1a39e4873a850032d48ef5dd2a 149 Pfam PF06271 RDD family 7 131 1.1E-19 T 22-04-2016 IPR010432 RDD MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.8E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.8E-8 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PANTHER PTHR24322 11 140 4.0E-50 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PANTHER PTHR24322 157 193 4.0E-50 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.7E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 SUPERFAMILY SSF51735 5 251 3.04E-81 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 Gene3D G3DSA:3.40.50.720 3 251 3.4E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10465 deaa19ec3d8a3a23f497c62941d6e4fe 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 2.3E-65 T 22-04-2016 MED134_RS14625 2bf846e648d26e558e14fe84e9341e19 66 Gene3D G3DSA:3.40.50.620 6 66 1.8E-8 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MED134_RS14625 2bf846e648d26e558e14fe84e9341e19 66 SUPERFAMILY SSF52402 9 65 1.3E-9 T 22-04-2016 MED134_RS10330 abf6b54f1c1b293cab184037ebd2c017 172 PANTHER PTHR39165:SF1 2 165 3.0E-32 T 22-04-2016 MED134_RS10330 abf6b54f1c1b293cab184037ebd2c017 172 Pfam PF04306 Protein of unknown function (DUF456) 24 160 1.2E-38 T 22-04-2016 IPR007403 Protein of unknown function DUF456 MED134_RS10330 abf6b54f1c1b293cab184037ebd2c017 172 PANTHER PTHR39165 2 165 3.0E-32 T 22-04-2016 MED134_RS00615 4ba3465ddfca03a725a4f64a682b2410 105 SUPERFAMILY SSF47226 4 104 5.63E-15 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS00615 4ba3465ddfca03a725a4f64a682b2410 105 Gene3D G3DSA:1.20.120.160 5 102 4.6E-11 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS00615 4ba3465ddfca03a725a4f64a682b2410 105 Pfam PF01627 Hpt domain 24 89 2.6E-5 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MED134_RS10090 709a7b4db8de2490e33260748d70519c 624 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 542 622 1.4E-25 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS10090 709a7b4db8de2490e33260748d70519c 624 Pfam PF13585 C-terminal domain of CHU protein family 542 614 5.9E-15 T 22-04-2016 MED134_RS12620 a489bd1ab2794d091ea6e8a1d8f82687 291 Pfam PF04116 Fatty acid hydroxylase superfamily 118 254 6.0E-24 T 22-04-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 MED134_RS09900 86ad0b31be3def65c60e7280a1d60c45 184 Pfam PF02674 Colicin V production protein 4 149 3.1E-27 T 22-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MED134_RS05770 9587bd054d12ffe020123cda649ec4d8 358 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 353 3.3E-65 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 MED134_RS05770 9587bd054d12ffe020123cda649ec4d8 358 PANTHER PTHR33529 1 358 9.3E-64 T 22-04-2016 MED134_RS05770 9587bd054d12ffe020123cda649ec4d8 358 PANTHER PTHR33529:SF1 1 358 9.3E-64 T 22-04-2016 MED134_RS14075 3790ba198ba644810652f289f48a0840 146 Pfam PF08818 Domain of unknown function (DU1801) 27 121 9.0E-8 T 22-04-2016 IPR014922 Domain of unknown function DUF1801 MED134_RS14075 3790ba198ba644810652f289f48a0840 146 SUPERFAMILY SSF159888 20 125 1.09E-6 T 22-04-2016 MED134_RS05330 b725578e04cc4fe2328624269161e31a 237 Pfam PF04012 PspA/IM30 family 2 230 3.9E-45 T 22-04-2016 IPR007157 PspA/IM30 MED134_RS05330 b725578e04cc4fe2328624269161e31a 237 PANTHER PTHR31088 2 233 1.3E-42 T 22-04-2016 MED134_RS05330 b725578e04cc4fe2328624269161e31a 237 PANTHER PTHR31088:SF0 2 233 1.3E-42 T 22-04-2016 MED134_RS05330 b725578e04cc4fe2328624269161e31a 237 SUPERFAMILY SSF57997 14 154 2.81E-6 T 22-04-2016 MED134_RS00665 88554e9bec0205d356083178ab245aa3 504 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 236 461 2.7E-8 T 22-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 MED134_RS00665 88554e9bec0205d356083178ab245aa3 504 SUPERFAMILY SSF51445 216 481 8.81E-50 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily MED134_RS00665 88554e9bec0205d356083178ab245aa3 504 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 328 337 - T 22-04-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 MED134_RS00665 88554e9bec0205d356083178ab245aa3 504 Gene3D G3DSA:3.20.20.80 217 465 1.5E-37 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 MED134_RS13635 0cd0d98b9fa79c858e4f9cd70557c1aa 129 SUPERFAMILY SSF51182 4 126 8.26E-42 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS13635 0cd0d98b9fa79c858e4f9cd70557c1aa 129 Pfam PF05523 WxcM-like, C-terminal 3 128 6.3E-52 T 22-04-2016 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 MED134_RS13635 0cd0d98b9fa79c858e4f9cd70557c1aa 129 Gene3D G3DSA:2.60.120.10 36 125 6.2E-9 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS02470 1552334e22324f5b6c71d85e9f158c64 271 Pfam PF01145 SPFH domain / Band 7 family 28 209 4.4E-27 T 22-04-2016 IPR001107 Band 7 domain MED134_RS02470 1552334e22324f5b6c71d85e9f158c64 271 PANTHER PTHR10264:SF78 1 245 7.9E-24 T 22-04-2016 MED134_RS02470 1552334e22324f5b6c71d85e9f158c64 271 SUPERFAMILY SSF117892 61 194 4.05E-22 T 22-04-2016 IPR001107 Band 7 domain MED134_RS02470 1552334e22324f5b6c71d85e9f158c64 271 SMART SM00244 25 189 1.3E-13 T 22-04-2016 IPR001107 Band 7 domain MED134_RS02470 1552334e22324f5b6c71d85e9f158c64 271 PANTHER PTHR10264 1 245 7.9E-24 T 22-04-2016 IPR001972 Stomatin family GO:0016020 MED134_RS03875 5ae532a4de7a1c498a2095b48a1847ef 217 Gene3D G3DSA:3.40.50.1820 38 192 8.0E-12 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS03875 5ae532a4de7a1c498a2095b48a1847ef 217 SUPERFAMILY SSF53474 4 210 4.61E-15 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS10615 27ea0c45428481b22610f4a24e9cd636 201 Pfam PF14014 Protein of unknown function (DUF4230) 40 185 8.5E-23 T 22-04-2016 IPR025324 Protein of unknown function DUF4230 MED134_RS13095 f361bf2d7b2017fc75a42ef2d123558c 531 Pfam PF01391 Collagen triple helix repeat (20 copies) 26 71 1.1E-7 T 22-04-2016 IPR008160 Collagen triple helix repeat MED134_RS12945 a4fbc475f535ff3b57df81a7af87b2fc 130 SUPERFAMILY SSF55961 9 125 3.3E-15 T 22-04-2016 MED134_RS12945 a4fbc475f535ff3b57df81a7af87b2fc 130 Gene3D G3DSA:3.30.530.20 9 121 3.0E-9 T 22-04-2016 IPR023393 START-like domain MED134_RS02055 7cf0db6e6c9076b19d9df6eba3a73ae4 485 SUPERFAMILY SSF52374 253 388 6.89E-9 T 22-04-2016 MED134_RS02055 7cf0db6e6c9076b19d9df6eba3a73ae4 485 SUPERFAMILY SSF52374 422 473 6.89E-9 T 22-04-2016 MED134_RS05445 51c976576d134c372944b8ab8760a9ce 97 Pfam PF05258 Protein of unknown function (DUF721) 10 95 3.4E-12 T 22-04-2016 IPR007922 Protein of unknown function DUF721/UPF0232 MED134_RS01985 8f33240566dd043797ffb19131a4a53d 121 Gene3D G3DSA:3.40.50.10600 72 117 3.7E-4 T 22-04-2016 IPR021866 SpoIIAA-like MED134_RS01985 8f33240566dd043797ffb19131a4a53d 121 SUPERFAMILY SSF52091 71 117 6.67E-5 T 22-04-2016 IPR002645 STAS domain MED134_RS03255 2849346dd48ac0a7f71f85f613814769 468 Pfam PF02646 RmuC family 151 448 8.0E-105 T 22-04-2016 IPR003798 DNA recombination RmuC MED134_RS03255 2849346dd48ac0a7f71f85f613814769 468 PANTHER PTHR30563 36 468 2.1E-100 T 22-04-2016 MED134_RS02300 a21bf785a20509e5546a6cf349bada1c 361 Gene3D G3DSA:2.40.160.20 47 191 3.3E-21 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS02300 a21bf785a20509e5546a6cf349bada1c 361 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 54 190 3.8E-12 T 22-04-2016 IPR018550 Lipid A 3-O-deacylase-related MED134_RS08845 338afafb123d097492c672725204f9fa 517 Gene3D G3DSA:3.30.70.1070 441 511 3.5E-4 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS08845 338afafb123d097492c672725204f9fa 517 SUPERFAMILY SSF110997 441 511 1.7E-6 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS13765 02571997d624c8bd2ec69c5c8595914e 113 Pfam PF11015 Protein of unknown function (DUF2853) 10 110 1.1E-45 T 22-04-2016 IPR021274 Protein of unknown function DUF2853 MED134_RS13765 02571997d624c8bd2ec69c5c8595914e 113 Gene3D G3DSA:1.10.238.120 1 112 4.6E-53 T 22-04-2016 IPR023154 Jann4075-like domain MED134_RS13765 02571997d624c8bd2ec69c5c8595914e 113 SUPERFAMILY SSF158587 1 112 2.88E-48 T 22-04-2016 IPR023154 Jann4075-like domain MED134_RS02385 b07381f2e0580b651667fc90a8aeef54 132 Pfam PF11680 Protein of unknown function (DUF3276) 2 129 8.4E-52 T 22-04-2016 IPR021694 Protein of unknown function DUF3276 MED134_RS02385 b07381f2e0580b651667fc90a8aeef54 132 SMART SM00712 11 82 0.0037 T 22-04-2016 IPR006628 Purine-rich element binding protein family MED134_RS01230 36608125d2c7ef5ade18c49367741071 210 PANTHER PTHR22936 7 205 9.7E-22 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 MED134_RS01230 36608125d2c7ef5ade18c49367741071 210 SUPERFAMILY SSF144091 4 178 2.09E-36 T 22-04-2016 MED134_RS01230 36608125d2c7ef5ade18c49367741071 210 Pfam PF01694 Rhomboid family 40 178 1.2E-27 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS01230 36608125d2c7ef5ade18c49367741071 210 Gene3D G3DSA:1.20.1540.10 5 179 4.4E-34 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MED134_RS00445 cb4944cb89b9e3ba2399d02e7f4c2fbd 78 Gene3D G3DSA:1.10.1220.10 23 75 5.3E-6 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MED134_RS00445 cb4944cb89b9e3ba2399d02e7f4c2fbd 78 SUPERFAMILY SSF47598 17 75 1.89E-5 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 MED134_RS07755 f3549dfc076b4744e9edf5a68c97f35b 301 SUPERFAMILY SSF56059 95 273 4.32E-13 T 22-04-2016 MED134_RS07755 f3549dfc076b4744e9edf5a68c97f35b 301 PANTHER PTHR39217 32 301 1.2E-61 T 22-04-2016 MED134_RS07755 f3549dfc076b4744e9edf5a68c97f35b 301 Gene3D G3DSA:3.30.470.20 179 249 8.0E-5 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 MED134_RS07755 f3549dfc076b4744e9edf5a68c97f35b 301 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 140 243 1.8E-5 T 22-04-2016 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 MED134_RS01780 51fac1015e98e392b72b5be457d2164a 775 Pfam PF13585 C-terminal domain of CHU protein family 691 764 1.9E-17 T 22-04-2016 MED134_RS01780 51fac1015e98e392b72b5be457d2164a 775 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 689 775 1.3E-30 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS05710 72dc4d9bb0c68c7321fa1cb0a3e5ee6b 103 Pfam PF15580 Immunity protein 53 6 96 1.4E-32 T 22-04-2016 IPR028228 Immunity protein 53 MED134_RS01595 07aa4a5a0df980fed966ebd72458dcb3 134 Pfam PF12869 tRNA_anti-like 28 125 4.4E-7 T 22-04-2016 IPR024422 Protein of unknown function, OB-fold-containing MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 PANTHER PTHR11620 1 59 1.4E-24 T 22-04-2016 MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 PANTHER PTHR11620 76 96 1.4E-24 T 22-04-2016 MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 SUPERFAMILY SSF54189 1 95 1.26E-27 T 22-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 Pfam PF00276 Ribosomal protein L23 3 92 2.6E-31 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 Gene3D G3DSA:3.30.70.330 1 96 1.3E-31 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 MED134_RS12245 2cdbab3941b2081e557606622c16b208 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 1 95 19.641 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MED134_RS11675 1705d29c5114c8a053c85bb3ef92b52d 668 Pfam PF14121 Putative porin 61 667 1.5E-154 T 22-04-2016 IPR025631 Putative porin-10 MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 PANTHER PTHR12553 185 300 2.4E-62 T 22-04-2016 MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 PANTHER PTHR12553 7 155 2.4E-62 T 22-04-2016 MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 Gene3D G3DSA:3.60.15.10 7 304 1.3E-68 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 SUPERFAMILY SSF56281 7 305 2.49E-69 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 7 303 1.8E-89 T 22-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 Pfam PF00753 Metallo-beta-lactamase superfamily 27 99 5.7E-10 T 22-04-2016 IPR001279 Metallo-beta-lactamase MED134_RS00985 f44cc6e661f947b74e9f57fc3212ad7c 305 Hamap MF_01818 Ribonuclease BN [rbn]. 5 305 30.76 T 22-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MED134_RS13115 9dbac018f12e25a07a9d4c6886bbbf2f 206 Pfam PF13709 Domain of unknown function (DUF4159) 7 204 4.4E-55 T 22-04-2016 IPR025297 Domain of unknown function DUF4159 MED134_RS08380 26726c9e68a17e8670e4d3376601aa52 143 PANTHER PTHR33293:SF1 21 139 5.1E-15 T 22-04-2016 MED134_RS08380 26726c9e68a17e8670e4d3376601aa52 143 PANTHER PTHR33293 21 139 5.1E-15 T 22-04-2016 MED134_RS08380 26726c9e68a17e8670e4d3376601aa52 143 Pfam PF03400 IS1 transposase 21 133 3.0E-25 T 22-04-2016 IPR005063 Transposase, IS1 GO:0003677|GO:0004803|GO:0006313 MED134_RS06915 fe6478c3a6e7ed6b86a0f6d43c98aa21 132 Pfam PF10990 Protein of unknown function (DUF2809) 26 114 2.4E-23 T 22-04-2016 IPR021257 Protein of unknown function DUF2809 MED134_RS06475 bb3f53720bf3c37cd2531430a043e722 304 Gene3D G3DSA:3.30.230.10 6 128 2.9E-7 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MED134_RS06475 bb3f53720bf3c37cd2531430a043e722 304 SUPERFAMILY SSF54211 5 179 7.17E-10 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold MED134_RS11325 a960a133172e38194be4533a901ba59a 193 PANTHER PTHR11403:SF0 19 191 8.2E-24 T 22-04-2016 MED134_RS11325 a960a133172e38194be4533a901ba59a 193 Gene3D G3DSA:1.20.120.80 12 191 4.2E-37 T 22-04-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 MED134_RS11325 a960a133172e38194be4533a901ba59a 193 Pfam PF00510 Cytochrome c oxidase subunit III 58 190 3.8E-14 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 MED134_RS11325 a960a133172e38194be4533a901ba59a 193 PANTHER PTHR11403 19 191 8.2E-24 T 22-04-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 MED134_RS11325 a960a133172e38194be4533a901ba59a 193 SUPERFAMILY SSF81452 3 191 2.09E-35 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 MED134_RS06495 1c5430b33d629a4f4a290fc32cf516d2 190 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 11 167 1.8E-15 T 22-04-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MED134_RS06495 1c5430b33d629a4f4a290fc32cf516d2 190 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 31 151 2.2E-6 T 22-04-2016 IPR010664 Lipopolysaccharide assembly, LptC-related MED134_RS10940 bd2fb4c161392d1fe035b89a64d47a5e 413 TIGRFAM TIGR04312 choice_anch_B: choice-of-anchor B domain 46 410 1.3E-168 T 22-04-2016 IPR027589 Choice-of-anchor B domain MED134_RS10940 bd2fb4c161392d1fe035b89a64d47a5e 413 SUPERFAMILY SSF101908 103 294 4.58E-5 T 22-04-2016 MED134_RS10940 bd2fb4c161392d1fe035b89a64d47a5e 413 PANTHER PTHR38787 44 408 5.7E-93 T 22-04-2016 MED134_RS03645 635c12c3400aae32600000cbca3fa1a8 287 PANTHER PTHR30329 135 286 3.4E-28 T 22-04-2016 MED134_RS03645 635c12c3400aae32600000cbca3fa1a8 287 Gene3D G3DSA:3.30.1330.60 145 265 3.4E-30 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03645 635c12c3400aae32600000cbca3fa1a8 287 Pfam PF00691 OmpA family 158 257 3.0E-18 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03645 635c12c3400aae32600000cbca3fa1a8 287 SUPERFAMILY SSF103088 150 265 1.96E-28 T 22-04-2016 IPR006665 OmpA-like domain MED134_RS03645 635c12c3400aae32600000cbca3fa1a8 287 PANTHER PTHR30329:SF4 135 286 3.4E-28 T 22-04-2016 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PANTHER PTHR24305 41 441 4.2E-86 T 22-04-2016 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PANTHER PTHR24305:SF21 41 441 4.2E-86 T 22-04-2016 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 384 393 - T 22-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 Gene3D G3DSA:1.10.630.10 4 441 9.5E-104 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 Pfam PF00067 Cytochrome P450 22 438 3.5E-77 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 391 414 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 246 263 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 32 51 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 381 391 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 266 292 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00463 E-class P450 group I signature 348 372 2.8E-23 T 22-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 SUPERFAMILY SSF48264 8 441 1.06E-95 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00385 P450 superfamily signature 309 320 1.2E-13 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00385 P450 superfamily signature 382 391 1.2E-13 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00385 P450 superfamily signature 257 274 1.2E-13 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS11235 431881e5dfab3907e49a9073439b0151 441 PRINTS PR00385 P450 superfamily signature 391 402 1.2E-13 T 22-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 MED134_RS01260 8812eab2e5aec7a10a72f6d34917d9a7 365 PANTHER PTHR21716 23 357 4.2E-36 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like MED134_RS01260 8812eab2e5aec7a10a72f6d34917d9a7 365 Pfam PF01594 Domain of unknown function DUF20 23 350 1.3E-38 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like MED134_RS11335 ae97c378fcc1b2dd0285543b29474c28 127 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 24 104 2.7E-20 T 22-04-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 Gene3D G3DSA:1.10.600.10 14 323 7.4E-96 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 201 213 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 PANTHER PTHR12001:SF23 13 324 1.8E-93 T 22-04-2016 MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 PANTHER PTHR12001 13 324 1.8E-93 T 22-04-2016 IPR017446 Polyprenyl synthetase-related MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 SUPERFAMILY SSF48576 16 323 9.92E-89 T 22-04-2016 IPR008949 Isoprenoid synthase domain MED134_RS07400 7b9a75f2e87bffd60711e3fcda3edcb9 324 Pfam PF00348 Polyprenyl synthetase 25 267 5.0E-75 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 MED134_RS06075 543ae873a7c401d073471090560f3a30 131 Pfam PF06170 Protein of unknown function (DUF983) 37 117 5.3E-10 T 22-04-2016 IPR009325 Protein of unknown function DUF983 MED134_RS10040 7c974def25483662f51e8eb8d2c9b9a7 210 Pfam PF04973 Nicotinamide mononucleotide transporter 21 201 1.1E-49 T 22-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MED134_RS10040 7c974def25483662f51e8eb8d2c9b9a7 210 PANTHER PTHR36122 21 206 2.1E-37 T 22-04-2016 MED134_RS10040 7c974def25483662f51e8eb8d2c9b9a7 210 PANTHER PTHR36122:SF1 21 206 2.1E-37 T 22-04-2016 MED134_RS10040 7c974def25483662f51e8eb8d2c9b9a7 210 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 22 202 7.4E-27 T 22-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MED134_RS08235 b22825617ff809798678a2c9890e436a 170 Pfam PF13858 Protein of unknown function (DUF4199) 7 169 2.7E-24 T 22-04-2016 IPR025250 Protein of unknown function DUF4199 MED134_RS08825 a9396d0968707e8deec9a48c9f11f35a 150 Gene3D G3DSA:3.30.479.10 2 145 8.0E-36 T 22-04-2016 MED134_RS08825 a9396d0968707e8deec9a48c9f11f35a 150 SUPERFAMILY SSF55620 2 146 4.56E-36 T 22-04-2016 MED134_RS08825 a9396d0968707e8deec9a48c9f11f35a 150 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 144 1.3E-31 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein MED134_RS08825 a9396d0968707e8deec9a48c9f11f35a 150 PANTHER PTHR12589 1 144 4.4E-28 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein MED134_RS14775 47a942deb1e94ca1d4b94e1b91fa65a6 827 Gene3D G3DSA:3.40.50.1820 279 554 4.6E-26 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS14775 47a942deb1e94ca1d4b94e1b91fa65a6 827 SUPERFAMILY SSF53474 273 522 1.44E-17 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00525 d7d5e55721a65638cb9b583e7d1fa86d 294 Pfam PF14499 Domain of unknown function (DUF4437) 43 291 3.8E-81 T 22-04-2016 IPR028013 Protein of unknown function DUF4437 MED134_RS00525 d7d5e55721a65638cb9b583e7d1fa86d 294 SUPERFAMILY SSF51182 38 156 6.21E-10 T 22-04-2016 IPR011051 RmlC-like cupin domain MED134_RS00525 d7d5e55721a65638cb9b583e7d1fa86d 294 Gene3D G3DSA:2.60.120.10 57 177 4.1E-15 T 22-04-2016 IPR014710 RmlC-like jelly roll fold MED134_RS07665 639b7a3ef9541257713c2b7bcc489f70 110 Pfam PF04977 Septum formation initiator 25 98 2.3E-7 T 22-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 MED134_RS05370 ca210782350932845826b875bf7e81c0 255 Gene3D G3DSA:3.40.50.300 3 253 2.2E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05370 ca210782350932845826b875bf7e81c0 255 SUPERFAMILY SSF52540 1 252 5.01E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS05370 ca210782350932845826b875bf7e81c0 255 PANTHER PTHR13696:SF52 1 253 2.2E-89 T 22-04-2016 MED134_RS05370 ca210782350932845826b875bf7e81c0 255 PANTHER PTHR13696 1 253 2.2E-89 T 22-04-2016 MED134_RS05370 ca210782350932845826b875bf7e81c0 255 Pfam PF13614 AAA domain 2 178 8.9E-69 T 22-04-2016 IPR025669 AAA domain MED134_RS13430 3d8ec99f7455d06331b8963cec43620e 466 SUPERFAMILY SSF53756 137 461 6.8E-12 T 22-04-2016 MED134_RS13430 3d8ec99f7455d06331b8963cec43620e 466 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 111 229 2.4E-5 T 22-04-2016 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 SUPERFAMILY SSF50939 167 422 1.04E-70 T 22-04-2016 IPR011040 Sialidases MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 SUPERFAMILY SSF50939 23 137 1.04E-70 T 22-04-2016 IPR011040 Sialidases MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 Pfam PF15902 Sortilin, neurotensin receptor 3, 173 297 8.3E-11 T 22-04-2016 IPR031778 Sortilin, N-terminal MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 Gene3D G3DSA:2.130.10.140 43 407 4.0E-88 T 22-04-2016 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 Gene3D G3DSA:2.130.10.140 555 722 2.2E-40 T 22-04-2016 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 Gene3D G3DSA:2.130.10.140 426 533 3.7E-6 T 22-04-2016 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 SUPERFAMILY SSF110296 440 457 7.06E-57 T 22-04-2016 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 SUPERFAMILY SSF110296 306 392 7.06E-57 T 22-04-2016 MED134_RS08640 6aaec2c07c3b3a03b3f813c67a1c82ee 1033 SUPERFAMILY SSF110296 513 705 7.06E-57 T 22-04-2016 MED134_RS00915 ae99d582e9258519cb9bfbc918b25740 106 Pfam PF13239 2TM domain 23 100 3.4E-27 T 22-04-2016 IPR025698 2TM domain MED134_RS11350 60058d1feea470505de3cde816c24734 181 Pfam PF04238 Protein of unknown function (DUF420) 47 175 2.8E-47 T 22-04-2016 IPR007352 Protein of unknown function DUF420 MED134_RS11350 60058d1feea470505de3cde816c24734 181 PANTHER PTHR37692 1 181 4.3E-46 T 22-04-2016 MED134_RS02085 4bd0dbd6393c3d42b30a0d6954450fea 287 Gene3D G3DSA:2.130.10.10 185 279 2.1E-7 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MED134_RS02085 4bd0dbd6393c3d42b30a0d6954450fea 287 Gene3D G3DSA:2.120.10.60 18 73 4.4E-7 T 22-04-2016 MED134_RS02085 4bd0dbd6393c3d42b30a0d6954450fea 287 Gene3D G3DSA:2.120.10.60 118 174 4.4E-7 T 22-04-2016 MED134_RS02085 4bd0dbd6393c3d42b30a0d6954450fea 287 SUPERFAMILY SSF69322 18 115 5.89E-11 T 22-04-2016 MED134_RS02085 4bd0dbd6393c3d42b30a0d6954450fea 287 SUPERFAMILY SSF69322 188 279 5.89E-11 T 22-04-2016 MED134_RS09000 471f86e99e4ba82f7e0d3f97489467b1 896 Pfam PF12705 PD-(D/E)XK nuclease superfamily 635 895 7.8E-27 T 22-04-2016 MED134_RS09000 471f86e99e4ba82f7e0d3f97489467b1 896 SUPERFAMILY SSF52540 265 642 1.17E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS09000 471f86e99e4ba82f7e0d3f97489467b1 896 SUPERFAMILY SSF52980 635 835 1.55E-7 T 22-04-2016 IPR011335 Restriction endonuclease type II-like MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 PANTHER PTHR11328 1 471 2.7E-70 T 22-04-2016 MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 Pfam PF13347 MFS/sugar transport protein 16 454 1.7E-71 T 22-04-2016 MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 Gene3D G3DSA:1.20.1250.20 15 207 1.1E-12 T 22-04-2016 MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 Gene3D G3DSA:1.20.1250.20 244 456 5.0E-12 T 22-04-2016 MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 PANTHER PTHR11328:SF24 1 471 2.7E-70 T 22-04-2016 MED134_RS13790 6f2484af1d72e924d8fb136cc64158a3 473 SUPERFAMILY SSF103473 14 448 2.75E-35 T 22-04-2016 IPR020846 Major facilitator superfamily domain MED134_RS14005 751a8c02ebbb2bbfa2073ebcf6d5f5b8 216 Pfam PF14123 Domain of unknown function (DUF4290) 5 176 7.1E-78 T 22-04-2016 IPR025632 Protein of unknown function DUF4290 MED134_RS03595 d046cd6b7eb0921e82715a944f512c58 144 Gene3D G3DSA:3.40.50.1000 29 140 1.5E-25 T 22-04-2016 IPR023214 HAD-like domain MED134_RS03595 d046cd6b7eb0921e82715a944f512c58 144 SUPERFAMILY SSF56784 29 124 9.26E-19 T 22-04-2016 IPR023214 HAD-like domain MED134_RS03190 dab632e16258144769299d978ca0832f 431 Pfam PF10011 Predicted membrane protein (DUF2254) 18 381 1.8E-98 T 22-04-2016 IPR018723 Protein of unknown function DUF2254, membrane MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 Pfam PF02699 Preprotein translocase subunit 11 82 1.2E-18 T 22-04-2016 IPR003849 Preprotein translocase YajC MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 12 83 8.3E-17 T 22-04-2016 IPR003849 Preprotein translocase YajC MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 6 26 5.7E-5 T 22-04-2016 IPR003849 Preprotein translocase YajC MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 44 62 5.7E-5 T 22-04-2016 IPR003849 Preprotein translocase YajC MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 SMART SM01323 6 86 4.0E-15 T 22-04-2016 IPR003849 Preprotein translocase YajC MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 PANTHER PTHR33909:SF1 11 81 5.4E-14 T 22-04-2016 MED134_RS02365 2b916ea38a4784ee3e0f44c4cfdcb597 99 PANTHER PTHR33909 11 81 5.4E-14 T 22-04-2016 MED134_RS07830 af6125553309b68d0dccc1d81e4228c8 162 Gene3D G3DSA:3.40.50.300 4 128 1.0E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07830 af6125553309b68d0dccc1d81e4228c8 162 SUPERFAMILY SSF52540 2 151 4.57E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase MED134_RS07830 af6125553309b68d0dccc1d81e4228c8 162 Pfam PF13671 AAA domain 4 149 5.3E-18 T 22-04-2016 MED134_RS13535 92be2e4289af318bc7f4892d51053332 179 Pfam PF07659 Domain of Unknown Function (DUF1599) 115 176 9.1E-29 T 22-04-2016 IPR011630 Clostridium phage phiCTP1, Gp74 MED134_RS13535 92be2e4289af318bc7f4892d51053332 179 Pfam PF07659 Domain of Unknown Function (DUF1599) 22 82 2.2E-26 T 22-04-2016 IPR011630 Clostridium phage phiCTP1, Gp74 MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 Pfam PF00248 Aldo/keto reductase family 15 335 5.2E-69 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 PANTHER PTHR11732:SF112 1 138 1.2E-144 T 22-04-2016 MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 PANTHER PTHR11732:SF112 157 344 1.2E-144 T 22-04-2016 MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 Gene3D G3DSA:3.20.20.100 1 340 2.9E-96 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 SUPERFAMILY SSF51430 1 342 8.38E-98 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 PANTHER PTHR11732 1 138 1.2E-144 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta MED134_RS08020 7f8f5aeb2f650545b2b04b6128c6b010 344 PANTHER PTHR11732 157 344 1.2E-144 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta MED134_RS03955 b7151bca7ec22f159c83e945abf65494 351 Pfam PF12412 Protein of unknown function (DUF3667) 68 110 4.6E-13 T 22-04-2016 IPR022134 Protein of unknown function DUF3667 MED134_RS00065 28130760cfd7838788ed17c15fd100b9 315 Pfam PF12146 Serine aminopeptidase, S33 80 278 3.7E-8 T 22-04-2016 IPR022742 Serine aminopeptidase, S33 MED134_RS00065 28130760cfd7838788ed17c15fd100b9 315 Gene3D G3DSA:3.40.50.1820 40 313 2.3E-29 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS00065 28130760cfd7838788ed17c15fd100b9 315 SUPERFAMILY SSF53474 38 294 1.11E-29 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold MED134_RS10830 3db05829fa19c669f7eb6fab40f7603a 308 Pfam PF11276 Protein of unknown function (DUF3078) 69 166 5.1E-18 T 22-04-2016 IPR021428 Protein of unknown function DUF3078 MED134_RS00920 92f1aff22a98181d3e51b1b757d3fa8c 103 Pfam PF13239 2TM domain 9 89 1.2E-16 T 22-04-2016 IPR025698 2TM domain MED134_RS12410 58f814cd97dc8249aa2ea3f0f1427185 594 Pfam PF05960 Bacterial protein of unknown function (DUF885) 51 586 2.0E-168 T 22-04-2016 IPR010281 Protein of unknown function DUF885 MED134_RS12410 58f814cd97dc8249aa2ea3f0f1427185 594 PANTHER PTHR33361:SF4 36 590 2.6E-178 T 22-04-2016 MED134_RS12410 58f814cd97dc8249aa2ea3f0f1427185 594 PANTHER PTHR33361 36 590 2.6E-178 T 22-04-2016 MED134_RS13130 b1548bf79024c4b763105b7e6c119891 427 Pfam PF07584 Aerotolerance regulator N-terminal 1 76 3.2E-17 T 22-04-2016 IPR024163 Aerotolerance regulator, N-terminal MED134_RS13130 b1548bf79024c4b763105b7e6c119891 427 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 1 79 2.3E-21 T 22-04-2016 IPR011933 Double transmembrane domain MED134_RS09445 e104e806f6631c2dce0773fc7f65d863 475 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 331 460 1.0E-13 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MED134_RS09445 e104e806f6631c2dce0773fc7f65d863 475 Pfam PF01943 Polysaccharide biosynthesis protein 4 259 1.3E-10 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MED134_RS02735 dfe95c4ea75aa99114d99923fb71342b 425 SUPERFAMILY SSF53756 4 68 5.76E-19 T 22-04-2016 MED134_RS02735 dfe95c4ea75aa99114d99923fb71342b 425 SUPERFAMILY SSF53756 113 402 5.76E-19 T 22-04-2016 MED134_RS12060 3b5581d8f01334a0df72fdc00dc99ddf 382 Pfam PF13585 C-terminal domain of CHU protein family 291 379 9.0E-28 T 22-04-2016 MED134_RS12060 3b5581d8f01334a0df72fdc00dc99ddf 382 TIGRFAM TIGR04131 Bac_Flav_CTERM: gliding motility-associated C-terminal domain 292 382 2.4E-16 T 22-04-2016 IPR026341 Gliding motility-associated, C-terminal domain MED134_RS10755 50f577c3e6a786ee1e48f1f4fc123e48 776 TIGRFAM TIGR04183 Por_Secre_tail: Por secretion system C-terminal sorting domain 708 776 6.1E-13 T 22-04-2016 IPR026444 Secretion system C-terminal sorting domain MED134_RS13485 db12c679d18103574d2b7aac3de95705 397 Pfam PF13387 Domain of unknown function (DUF4105) 31 169 6.1E-22 T 22-04-2016 IPR025178 Domain of unknown function DUF4105 MED134_RS00380 66983abc35e02b363e4299cae235511a 293 Gene3D G3DSA:3.40.50.2300 1 134 2.9E-6 T 22-04-2016 MED134_RS11575 bf8aea061c67fabbad2c71085b3cf2d9 188 Pfam PF13590 Domain of unknown function (DUF4136) 24 183 6.7E-32 T 22-04-2016 IPR025411 Domain of unknown function DUF4136 MED134_RS04500 dfb614bf800737976cd1ac51aad6feda 202 Gene3D G3DSA:2.40.160.20 7 171 2.0E-4 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04500 dfb614bf800737976cd1ac51aad6feda 202 SUPERFAMILY SSF56925 25 202 8.63E-6 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS04500 dfb614bf800737976cd1ac51aad6feda 202 Pfam PF13568 Outer membrane protein beta-barrel domain 19 177 2.5E-32 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS07985 c7f3a38c9039d3af818bcae407fbf0b5 270 PANTHER PTHR12526:SF17 5 237 1.2E-15 T 22-04-2016 MED134_RS07985 c7f3a38c9039d3af818bcae407fbf0b5 270 PANTHER PTHR12526 5 237 1.2E-15 T 22-04-2016 MED134_RS07985 c7f3a38c9039d3af818bcae407fbf0b5 270 SUPERFAMILY SSF53756 5 246 2.93E-19 T 22-04-2016 MED134_RS07985 c7f3a38c9039d3af818bcae407fbf0b5 270 Pfam PF08323 Starch synthase catalytic domain 5 235 2.8E-47 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 MED134_RS01835 b0347a8f75a230fd33df0281c6430fb3 116 Pfam PF13564 DoxX-like family 7 103 1.4E-11 T 22-04-2016 IPR032808 DoxX family MED134_RS05315 65564051e2b980d64a2e5d3c63b4af36 245 PANTHER PTHR39200:SF1 3 231 7.4E-12 T 22-04-2016 MED134_RS05315 65564051e2b980d64a2e5d3c63b4af36 245 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 45 226 1.4E-39 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS05315 65564051e2b980d64a2e5d3c63b4af36 245 PANTHER PTHR39200 3 231 7.4E-12 T 22-04-2016 MED134_RS04595 5e493f2ee98aca6b3668bdca0229e2a8 68 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 1.0E-19 T 22-04-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type MED134_RS04595 5e493f2ee98aca6b3668bdca0229e2a8 68 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 4.0E-10 T 22-04-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type MED134_RS06925 7465787b6cd7624309a98e8c58899a8d 182 Pfam PF16267 Domain of unknown function (DUF4920) 72 157 1.5E-35 T 22-04-2016 IPR032577 Protein of unknown function DUF4920 MED134_RS00715 9d653024a7fdefaefafbfff9606f4c14 137 Pfam PF01475 Ferric uptake regulator family 11 114 3.9E-9 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MED134_RS00715 9d653024a7fdefaefafbfff9606f4c14 137 SUPERFAMILY SSF46785 3 133 5.31E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS00715 9d653024a7fdefaefafbfff9606f4c14 137 Gene3D G3DSA:1.10.10.10 1 78 6.8E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 Gene3D G3DSA:2.30.40.10 3 70 3.1E-21 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 430 2.7E-89 T 22-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 Pfam PF01979 Amidohydrolase family 52 426 4.0E-23 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 SUPERFAMILY SSF51338 1 55 4.33E-32 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 SUPERFAMILY SSF51338 373 437 4.33E-32 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 SUPERFAMILY SSF51556 56 374 6.49E-94 T 22-04-2016 IPR032466 Metal-dependent hydrolase MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 ProSitePatterns PS00483 Dihydroorotase signature 2. 309 320 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 Gene3D G3DSA:3.20.20.140 71 413 1.3E-105 T 22-04-2016 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 PANTHER PTHR11647:SF1 1 430 4.2E-139 T 22-04-2016 MED134_RS10725 ccf174588baf5a8b8adb85c87c16bdc5 446 PANTHER PTHR11647 1 430 4.2E-139 T 22-04-2016 MED134_RS10510 d8475486ec4fcb68d94981c6294a1577 739 SUPERFAMILY SSF48230 126 369 1.37E-15 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase MED134_RS10510 d8475486ec4fcb68d94981c6294a1577 739 Pfam PF07940 Heparinase II/III-like protein 404 606 8.0E-9 T 22-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 MED134_RS10510 d8475486ec4fcb68d94981c6294a1577 739 Pfam PF16889 Heparinase II/III N-terminus 130 348 3.6E-23 T 22-04-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 MED134_RS10510 d8475486ec4fcb68d94981c6294a1577 739 PANTHER PTHR39210 26 573 2.1E-17 T 22-04-2016 MED134_RS06775 bf579e05d58adf4ac2a2c66d276f653d 337 PANTHER PTHR10188:SF23 49 314 1.5E-102 T 22-04-2016 MED134_RS06775 bf579e05d58adf4ac2a2c66d276f653d 337 Pfam PF01112 Asparaginase 56 327 8.3E-72 T 22-04-2016 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MED134_RS06775 bf579e05d58adf4ac2a2c66d276f653d 337 PANTHER PTHR10188 49 314 1.5E-102 T 22-04-2016 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MED134_RS06775 bf579e05d58adf4ac2a2c66d276f653d 337 SUPERFAMILY SSF56235 49 327 1.47E-77 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal MED134_RS10530 777e0a69547bba941b313413aa2d3282 155 Gene3D G3DSA:3.90.360.10 52 111 8.3E-4 T 22-04-2016 IPR019467 Histone acetyl transferase HAT1 N-terminal GO:0004402|GO:0016568 MED134_RS01270 561a835916475a8117813e02e6f2d862 215 Pfam PF13709 Domain of unknown function (DUF4159) 23 213 1.1E-64 T 22-04-2016 IPR025297 Domain of unknown function DUF4159 MED134_RS13915 65f6fa920afd919cfb152ec1ea81c1d4 297 Pfam PF14054 Domain of unknown function (DUF4249) 6 277 3.6E-19 T 22-04-2016 IPR025345 Protein of unknown function DUF4249 MED134_RS06085 b9c493510d0c12b3586543c33778f822 296 TIGRFAM TIGR03523 GldN: gliding motility associated protein GldN 6 296 1.6E-75 T 22-04-2016 IPR019847 Gliding motility associated protein GldN MED134_RS08110 0ae672fdc39ed7b1230c66d9dd83bcd3 188 Pfam PF11307 Protein of unknown function (DUF3109) 1 180 2.2E-78 T 22-04-2016 IPR021458 Protein of unknown function DUF3109 MED134_RS14240 ae4e42f33c180aea6f42e19d9b7a206b 182 Gene3D G3DSA:3.40.50.150 20 122 6.6E-4 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS14240 ae4e42f33c180aea6f42e19d9b7a206b 182 Pfam PF14060 Domain of unknown function (DUF4252) 9 159 1.0E-25 T 22-04-2016 IPR025348 Protein of unknown function DUF4252 MED134_RS08340 15785d388e19cea214b379f9cce96385 419 SUPERFAMILY SSF49265 245 414 7.52E-7 T 22-04-2016 IPR003961 Fibronectin type III GO:0005515 MED134_RS08340 15785d388e19cea214b379f9cce96385 419 Gene3D G3DSA:2.60.40.10 245 313 7.7E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold MED134_RS00555 5b3d5a05709ef17b2d407d3d6d175e37 209 Pfam PF14064 HmuY protein 57 197 9.8E-11 T 22-04-2016 IPR025921 HmuY protein MED134_RS06550 3fe82992d7f149109687df9cc08b944c 444 Pfam PF00474 Sodium:solute symporter family 45 197 8.5E-7 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MED134_RS13885 53a123a58f434b262200d88479d7ac1b 92 Pfam PF10825 Protein of unknown function (DUF2752) 8 55 4.6E-15 T 22-04-2016 IPR021215 Protein of unknown function DUF2752 MED134_RS14475 daf2de2861de9fe4952bfaa825a3384e 91 Pfam PF09834 Predicted membrane protein (DUF2061) 31 82 7.2E-22 T 22-04-2016 IPR018638 Domain of unknown function DUF2061, membrane MED134_RS13845 8a82ff0a7b5f139c74655f50e08cff61 222 Pfam PF02535 ZIP Zinc transporter 85 220 4.9E-12 T 22-04-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MED134_RS00965 b4ed38d2438ffa8cd7db26d0e9732e27 452 Pfam PF07012 Curlin associated repeat 143 176 3.5E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS00965 b4ed38d2438ffa8cd7db26d0e9732e27 452 Pfam PF07012 Curlin associated repeat 165 197 3.7E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS00965 b4ed38d2438ffa8cd7db26d0e9732e27 452 Pfam PF07012 Curlin associated repeat 363 396 7.6E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS00965 b4ed38d2438ffa8cd7db26d0e9732e27 452 Pfam PF07012 Curlin associated repeat 264 295 3.0E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS05035 3d54a3c2cd5062e4de4d35e47196be85 350 Pfam PF06580 Histidine kinase 164 241 2.0E-22 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MED134_RS05035 3d54a3c2cd5062e4de4d35e47196be85 350 PANTHER PTHR34220:SF1 1 350 1.3E-46 T 22-04-2016 MED134_RS05035 3d54a3c2cd5062e4de4d35e47196be85 350 PANTHER PTHR34220 1 350 1.3E-46 T 22-04-2016 MED134_RS05035 3d54a3c2cd5062e4de4d35e47196be85 350 Gene3D G3DSA:3.30.565.10 212 299 4.5E-4 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain MED134_RS05780 99c8ee10bc94bf8749e6a3b4248a1078 411 Pfam PF01566 Natural resistance-associated macrophage protein 28 377 5.2E-16 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 MED134_RS09340 fb1cbd7c7940c3de53b16255ffc10c5d 203 Pfam PF14063 Protein of unknown function (DUF4254) 40 182 1.6E-65 T 22-04-2016 IPR025350 Protein of unknown function DUF4254 MED134_RS12655 e23beb1547d9645261f39d1bd978efe9 207 Pfam PF14224 Domain of unknown function (DUF4331) 42 206 1.5E-6 T 22-04-2016 IPR025566 Protein of unknown function DUF4331 MED134_RS11615 6eb1de0f667835f323f4cd17effe7f08 490 SUPERFAMILY SSF48452 94 126 1.73E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11615 6eb1de0f667835f323f4cd17effe7f08 490 SUPERFAMILY SSF48452 251 361 1.73E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11615 6eb1de0f667835f323f4cd17effe7f08 490 Gene3D G3DSA:1.25.40.10 212 364 5.9E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS11615 6eb1de0f667835f323f4cd17effe7f08 490 Gene3D G3DSA:1.25.40.10 96 164 5.9E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MED134_RS09215 f7acdeb4863f7c8e9fdc95cb78ade00d 62 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 10 55 4.6E-19 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MED134_RS09215 f7acdeb4863f7c8e9fdc95cb78ade00d 62 PANTHER PTHR33162 6 62 3.8E-14 T 22-04-2016 MED134_RS09215 f7acdeb4863f7c8e9fdc95cb78ade00d 62 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 8 61 19.006 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MED134_RS09215 f7acdeb4863f7c8e9fdc95cb78ade00d 62 Pfam PF02416 mttA/Hcf106 family 11 61 3.0E-18 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MED134_RS13310 ae0aee900a920ea7ba6710b49a7910e2 73 Pfam PF11387 Protein of unknown function (DUF2795) 11 56 3.0E-17 T 22-04-2016 IPR021527 Protein of unknown function DUF2795 MED134_RS10030 213624cc83b50b89a3a08acee7801377 319 Gene3D G3DSA:2.60.40.1120 22 78 4.7E-4 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07045 4cdca05404219fbd84fd361657c4311a 417 Pfam PF17116 Domain of unknown function (DUF5103) 30 313 7.9E-96 T 22-04-2016 IPR031345 Protein of unknown function DUF5103 MED134_RS06955 d36ab802c5950ba5fbad32e4ed582cc9 128 PANTHER PTHR34980 1 123 1.2E-30 T 22-04-2016 MED134_RS06955 d36ab802c5950ba5fbad32e4ed582cc9 128 Pfam PF05656 Protein of unknown function (DUF805) 12 122 5.3E-33 T 22-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 MED134_RS06975 6c64e1b922416e4956ed680523d20474 332 PANTHER PTHR30040:SF3 1 332 7.2E-71 T 22-04-2016 MED134_RS06975 6c64e1b922416e4956ed680523d20474 332 PANTHER PTHR30040 1 332 7.2E-71 T 22-04-2016 MED134_RS06975 6c64e1b922416e4956ed680523d20474 332 Pfam PF02424 ApbE family 32 313 3.4E-69 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 MED134_RS06975 6c64e1b922416e4956ed680523d20474 332 SUPERFAMILY SSF143631 26 330 3.14E-76 T 22-04-2016 IPR003374 ApbE-like domain MED134_RS06975 6c64e1b922416e4956ed680523d20474 332 PIRSF PIRSF006268 1 332 2.8E-68 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 MED134_RS02855 fbde92e13a36a4ee1af7c9eb822e8d2a 198 PANTHER PTHR23026 14 195 9.5E-15 T 22-04-2016 MED134_RS02855 fbde92e13a36a4ee1af7c9eb822e8d2a 198 Pfam PF00881 Nitroreductase family 73 157 1.2E-7 T 22-04-2016 IPR029479 Nitroreductase MED134_RS02855 fbde92e13a36a4ee1af7c9eb822e8d2a 198 Pfam PF00881 Nitroreductase family 15 56 3.5E-7 T 22-04-2016 IPR029479 Nitroreductase MED134_RS02855 fbde92e13a36a4ee1af7c9eb822e8d2a 198 SUPERFAMILY SSF55469 11 193 1.13E-35 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS02855 fbde92e13a36a4ee1af7c9eb822e8d2a 198 Gene3D G3DSA:3.40.109.10 4 193 2.8E-37 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 MED134_RS11120 4768a7ef148ade3ab9f1d89d4224fdc0 152 Gene3D G3DSA:3.10.50.30 88 142 6.5E-5 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MED134_RS03205 9724ad5d032b2a84ecd678931ce0b4f4 410 Pfam PF02687 FtsX-like permease family 278 403 1.8E-16 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 MED134_RS03205 9724ad5d032b2a84ecd678931ce0b4f4 410 Pfam PF12704 MacB-like periplasmic core domain 28 207 6.8E-9 T 22-04-2016 IPR025857 MacB-like periplasmic core domain MED134_RS03205 9724ad5d032b2a84ecd678931ce0b4f4 410 PANTHER PTHR30489 21 410 5.8E-35 T 22-04-2016 MED134_RS11185 a01e49609ee971963606e2834cf05596 129 Pfam PF05036 Sporulation related domain 56 124 1.7E-6 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 MED134_RS12135 e83ebbeb48beebcf155c16ec8c346f18 146 Pfam PF07606 Protein of unknown function (DUF1569) 12 144 7.7E-12 T 22-04-2016 IPR011463 Protein of unknown function DUF1569 MED134_RS08590 22288bac9540989fa09048e0d8d132d7 137 PANTHER PTHR40052:SF2 1 135 1.5E-56 T 22-04-2016 MED134_RS08590 22288bac9540989fa09048e0d8d132d7 137 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 2 135 2.3E-62 T 22-04-2016 IPR009474 Putative bacilliredoxin, YphP/YqiW family MED134_RS08590 22288bac9540989fa09048e0d8d132d7 137 PANTHER PTHR40052 1 135 1.5E-56 T 22-04-2016 MED134_RS08590 22288bac9540989fa09048e0d8d132d7 137 Pfam PF06491 Disulphide isomerase 2 135 9.7E-63 T 22-04-2016 IPR009474 Putative bacilliredoxin, YphP/YqiW family MED134_RS08415 b03bdad1ae4846288853d4cdd504c434 288 Pfam PF03432 Relaxase/Mobilisation nuclease domain 10 226 5.0E-15 T 22-04-2016 IPR005094 Endonuclease relaxase, MobA/VirD2 MED134_RS05295 fdf47f2d895ecc61867e16df169376ea 176 Pfam PF09685 Domain of unknown function (DUF4870) 10 153 1.6E-31 T 22-04-2016 IPR019109 Protein of unknown function DUF4870 MED134_RS06690 bf1fb8596776a25a46d3be9c880dbb07 65 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 57 17.247 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 MED134_RS06690 bf1fb8596776a25a46d3be9c880dbb07 65 PANTHER PTHR35534 1 63 1.5E-19 T 22-04-2016 MED134_RS06690 bf1fb8596776a25a46d3be9c880dbb07 65 Pfam PF01783 Ribosomal L32p protein family 2 59 7.0E-21 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 MED134_RS06690 bf1fb8596776a25a46d3be9c880dbb07 65 SUPERFAMILY SSF57829 1 57 2.69E-17 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 MED134_RS06690 bf1fb8596776a25a46d3be9c880dbb07 65 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 57 4.8E-17 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 MED134_RS12030 8402ea38a05b845a9c9b7396b4deffbc 174 Pfam PF13590 Domain of unknown function (DUF4136) 21 172 3.6E-14 T 22-04-2016 IPR025411 Domain of unknown function DUF4136 MED134_RS00825 d9bcc648d4c1a01ed0889ea35ebb8aa8 128 Gene3D G3DSA:1.10.3420.10 2 127 1.1E-43 T 22-04-2016 IPR023292 NTP pyrophosphohydrolase-like domain MED134_RS00825 d9bcc648d4c1a01ed0889ea35ebb8aa8 128 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 93 7.4E-22 T 22-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 MED134_RS06045 486345f22876308a7e519e6afc720630 59 Pfam PF14255 Cysteine-rich CPXCG 7 48 6.0E-16 T 22-04-2016 IPR025990 Cysteine-rich CPXCG protein MED134_RS06200 6b72344d81befdd2cc35bbd6bea78d05 187 Pfam PF11827 Protein of unknown function (DUF3347) 13 182 1.7E-42 T 22-04-2016 IPR021782 Protein of unknown function DUF3347 MED134_RS04550 7613bcc5bcf7ff4802e7f484b2b81142 128 Gene3D G3DSA:3.30.530.20 1 126 1.3E-17 T 22-04-2016 IPR023393 START-like domain MED134_RS04550 7613bcc5bcf7ff4802e7f484b2b81142 128 SUPERFAMILY SSF55961 1 127 1.55E-19 T 22-04-2016 MED134_RS06890 2820435ca84d1e31249ff6971e4249f9 118 SUPERFAMILY SSF159888 2 108 4.58E-27 T 22-04-2016 MED134_RS06890 2820435ca84d1e31249ff6971e4249f9 118 Pfam PF08818 Domain of unknown function (DU1801) 15 106 1.8E-14 T 22-04-2016 IPR014922 Domain of unknown function DUF1801 MED134_RS10715 6457300a8887c1f98b9d815064a0919d 218 Pfam PF14093 Domain of unknown function (DUF4271) 14 216 7.8E-32 T 22-04-2016 IPR025367 Protein of unknown function DUF4271 MED134_RS10560 78bc7b7b63728370be0c9be23bb5cc4a 283 Pfam PF14240 YHYH protein 137 227 3.5E-10 T 22-04-2016 IPR025924 YHYH domain MED134_RS08230 b831183c4611675b2567f3a5547ba544 131 Gene3D G3DSA:3.10.180.10 14 126 1.2E-14 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS08230 b831183c4611675b2567f3a5547ba544 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 119 3.5E-4 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MED134_RS08230 b831183c4611675b2567f3a5547ba544 131 SUPERFAMILY SSF54593 5 124 1.61E-20 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MED134_RS03780 e9eb31e72cedc07720c5f0e000ad4180 170 Pfam PF09851 Short C-terminal domain 142 168 7.5E-7 T 22-04-2016 IPR018649 SHOCT domain MED134_RS07455 9cb2dd97a1b70f8389a5622479da475c 265 Pfam PF10977 Protein of unknown function (DUF2797) 37 259 1.9E-90 T 22-04-2016 IPR021246 Protein of unknown function DUF2797 MED134_RS03320 7f4ae0095e0da6a25a098d97baaf43b8 290 Pfam PF12388 Dual-action HEIGH metallo-peptidase 83 290 1.6E-82 T 22-04-2016 IPR024653 Peptidase, metallopeptidase M10/M27/M57 MED134_RS03320 7f4ae0095e0da6a25a098d97baaf43b8 290 SUPERFAMILY SSF55486 261 290 1.47E-18 T 22-04-2016 MED134_RS03320 7f4ae0095e0da6a25a098d97baaf43b8 290 SUPERFAMILY SSF55486 133 231 1.47E-18 T 22-04-2016 MED134_RS03320 7f4ae0095e0da6a25a098d97baaf43b8 290 Gene3D G3DSA:3.40.390.10 102 290 2.3E-13 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MED134_RS04665 071c27b841ef2faa12873b601be84938 151 Gene3D G3DSA:1.20.120.450 1 148 2.3E-39 T 22-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase MED134_RS04665 071c27b841ef2faa12873b601be84938 151 Pfam PF12867 DinB superfamily 14 143 2.7E-14 T 22-04-2016 IPR024775 DinB-like domain MED134_RS04665 071c27b841ef2faa12873b601be84938 151 SUPERFAMILY SSF109854 6 148 1.68E-24 T 22-04-2016 MED134_RS06625 670b405ee2be22d40b389546a5cb973f 51 Pfam PF01679 Proteolipid membrane potential modulator 3 48 1.9E-23 T 22-04-2016 IPR000612 Proteolipid membrane potential modulator GO:0016021 MED134_RS06625 670b405ee2be22d40b389546a5cb973f 51 PANTHER PTHR21659 3 48 1.3E-17 T 22-04-2016 IPR000612 Proteolipid membrane potential modulator GO:0016021 MED134_RS06625 670b405ee2be22d40b389546a5cb973f 51 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 7 22 - T 22-04-2016 IPR000612 Proteolipid membrane potential modulator GO:0016021 MED134_RS05685 45e8a301adbc6ec32f86fef8cd94ac38 71 Gene3D G3DSA:1.10.260.40 5 62 9.6E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS05685 45e8a301adbc6ec32f86fef8cd94ac38 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 61 3.4E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MED134_RS05685 45e8a301adbc6ec32f86fef8cd94ac38 71 SUPERFAMILY SSF47413 3 61 1.52E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MED134_RS06695 b5fdc9158032154337ecfdda57d8d6e5 179 Pfam PF02620 Uncharacterized ACR, COG1399 59 175 1.0E-19 T 22-04-2016 IPR003772 Protein of unknown function DUF177 MED134_RS02760 b1c65d3bbe3b7ca8a495b26899f3b353 127 Gene3D G3DSA:3.40.50.720 3 123 1.6E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS02760 b1c65d3bbe3b7ca8a495b26899f3b353 127 Pfam PF13380 CoA binding domain 3 121 1.8E-17 T 22-04-2016 IPR003781 CoA-binding GO:0048037 MED134_RS02760 b1c65d3bbe3b7ca8a495b26899f3b353 127 SUPERFAMILY SSF51735 3 124 8.53E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 Gene3D G3DSA:3.40.1190.20 1 334 1.7E-72 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 PANTHER PTHR10584:SF203 223 330 4.2E-89 T 22-04-2016 MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 PANTHER PTHR10584:SF203 1 205 4.2E-89 T 22-04-2016 MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 PANTHER PTHR10584 223 330 4.2E-89 T 22-04-2016 MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 PANTHER PTHR10584 1 205 4.2E-89 T 22-04-2016 MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 SUPERFAMILY SSF53613 1 330 4.37E-69 T 22-04-2016 IPR029056 Ribokinase-like MED134_RS10460 fb0e7562e5349678f81bc0b2a6a455a1 340 Pfam PF00294 pfkB family carbohydrate kinase 1 309 1.8E-28 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB MED134_RS09130 54a9b5143a199d3e2b99bce0c96ca3b8 124 Pfam PF12732 YtxH-like protein 8 78 2.0E-15 T 22-04-2016 IPR024623 Uncharacterised protein family YtxH MED134_RS11940 90f61ff03ec0d4a76fb2b2ea10a2d3c6 245 PANTHER PTHR30188 1 243 3.3E-52 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MED134_RS11940 90f61ff03ec0d4a76fb2b2ea10a2d3c6 245 Pfam PF02405 Permease MlaE 32 242 2.0E-58 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MED134_RS09055 db6e83a9fe3306c260561eb1723f7c12 118 SUPERFAMILY SSF51306 20 99 8.55E-13 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C MED134_RS09055 db6e83a9fe3306c260561eb1723f7c12 118 PANTHER PTHR33516:SF1 21 98 2.5E-14 T 22-04-2016 MED134_RS09055 db6e83a9fe3306c260561eb1723f7c12 118 Gene3D G3DSA:2.10.109.10 24 104 4.6E-18 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain MED134_RS09055 db6e83a9fe3306c260561eb1723f7c12 118 PANTHER PTHR33516 21 98 2.5E-14 T 22-04-2016 MED134_RS02890 beb1e80c470894a236604b66dd9d095d 267 Pfam PF08907 Domain of unknown function (DUF1853) 21 254 4.9E-52 T 22-04-2016 IPR015003 Protein of unknown function DUF1853 MED134_RS00165 bc6d8392eb6e395821952e123719d4ee 137 Pfam PF08818 Domain of unknown function (DU1801) 26 130 4.9E-9 T 22-04-2016 IPR014922 Domain of unknown function DUF1801 MED134_RS00165 bc6d8392eb6e395821952e123719d4ee 137 SUPERFAMILY SSF159888 70 134 1.23E-8 T 22-04-2016 MED134_RS00740 a4d7b8692aeba242efebe8d276d06d1d 169 Pfam PF11827 Protein of unknown function (DUF3347) 23 164 2.0E-42 T 22-04-2016 IPR021782 Protein of unknown function DUF3347 MED134_RS02975 3ebf28aef7b200e44a9947d6265b1367 361 Pfam PF05893 Acyl-CoA reductase (LuxC) 54 217 1.1E-6 T 22-04-2016 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723|UniPathway: UPA00569 MED134_RS02975 3ebf28aef7b200e44a9947d6265b1367 361 SUPERFAMILY SSF53720 95 244 7.29E-7 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MED134_RS02740 e244d467cef14d46cdea8aaa997c18e2 808 PANTHER PTHR38454:SF1 1 791 9.3E-23 T 22-04-2016 MED134_RS02740 e244d467cef14d46cdea8aaa997c18e2 808 Pfam PF09586 Bacterial membrane protein YfhO 700 779 3.2E-8 T 22-04-2016 IPR018580 Uncharacterised protein family YfhO MED134_RS02740 e244d467cef14d46cdea8aaa997c18e2 808 PANTHER PTHR38454 1 791 9.3E-23 T 22-04-2016 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 Pfam PF13585 C-terminal domain of CHU protein family 1833 1927 1.6E-22 T 22-04-2016 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1208 1238 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1082 1112 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1334 1364 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1586 1616 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1714 1742 1.8E-6 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 956 986 1.9E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 445 474 5.2E-4 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 578 608 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 704 734 1.9E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 830 860 1.9E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS00010 d3a537a0c7290c40d8490399903809c8 1929 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1460 1490 1.3E-8 T 22-04-2016 IPR001434 Domain of unknown function DUF11 MED134_RS03430 c0112e27fa6b90346a2a8571d99c1803 130 SUPERFAMILY SSF49503 28 118 1.33E-5 T 22-04-2016 IPR008972 Cupredoxin MED134_RS03430 c0112e27fa6b90346a2a8571d99c1803 130 Gene3D G3DSA:2.60.40.420 37 119 3.2E-6 T 22-04-2016 IPR008972 Cupredoxin MED134_RS11985 b401a70c880baa557ffdd6d9e61dabc3 158 SUPERFAMILY SSF55961 1 135 1.75E-17 T 22-04-2016 MED134_RS13355 8cdd915244ed705171df8cbe3a12cc4a 271 Pfam PF04230 Polysaccharide pyruvyl transferase 87 199 7.1E-12 T 22-04-2016 IPR007345 Polysaccharide pyruvyl transferase MED134_RS07770 6950dbadda888f3ca82d562931111da0 570 PANTHER PTHR33361:SF6 50 569 5.8E-164 T 22-04-2016 MED134_RS07770 6950dbadda888f3ca82d562931111da0 570 PANTHER PTHR33361 50 569 5.8E-164 T 22-04-2016 MED134_RS07770 6950dbadda888f3ca82d562931111da0 570 Pfam PF05960 Bacterial protein of unknown function (DUF885) 47 562 1.7E-158 T 22-04-2016 IPR010281 Protein of unknown function DUF885 MED134_RS05665 89f3f0282485561f73c5127b9cc3ed26 193 Pfam PF06347 Bacterial SH3 domain 134 184 9.4E-5 T 22-04-2016 IPR010466 Protein of unknown function DUF1058 MED134_RS03880 66279b379f8da573ef44aa4420ef51f5 99 SUPERFAMILY SSF55729 7 95 3.39E-6 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase MED134_RS08070 e7a944b23b80105e78bf08b9f81287bb 554 Pfam PF13205 Bacterial Ig-like domain 43 137 1.0E-12 T 22-04-2016 IPR032812 SbsA, Ig-like domain MED134_RS07980 c81bed130a6a4720ab8ea2ae34e05c9c 592 Pfam PF14092 Domain of unknown function (DUF4270) 30 575 8.8E-93 T 22-04-2016 IPR025366 Protein of unknown function DUF4270 MED134_RS09465 1670ba9dac4a91731adeb488c02f9fe0 259 Pfam PF14125 Domain of unknown function (DUF4292) 45 253 1.4E-57 T 22-04-2016 IPR025634 Protein of unknown function DUF4292 MED134_RS09595 0bbe52310d924b59392649aeb524a0f5 87 Pfam PF11297 Protein of unknown function (DUF3098) 17 83 8.5E-34 T 22-04-2016 IPR021448 Protein of unknown function DUF3098 MED134_RS12095 55dfc0f7467595a10007c553c7b5385d 243 SUPERFAMILY SSF49464 4 83 1.96E-8 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS12095 55dfc0f7467595a10007c553c7b5385d 243 Pfam PF13715 CarboxypepD_reg-like domain 3 85 3.8E-9 T 22-04-2016 MED134_RS01310 fe16af562053cb491c98efac00b453f0 186 Pfam PF13548 Domain of unknown function (DUF4126) 9 180 5.9E-52 T 22-04-2016 IPR025196 Domain of unknown function DUF4126 MED134_RS10840 26a778d46bf68a810db39cc4b2c81003 169 Pfam PF10652 Protein of unknown function (DUF2480) 3 167 3.3E-74 T 22-04-2016 IPR018914 Protein of unknown function DUF2480 MED134_RS01495 aabf3636f611e86e4c3a1a24188907c0 359 Pfam PF06439 Domain of Unknown Function (DUF1080) 56 178 1.2E-12 T 22-04-2016 IPR010496 Domain of unknown function DUF1080 MED134_RS01295 411bc7e249dbfa2f49286308685437b0 263 Gene3D G3DSA:3.40.50.150 45 131 9.9E-5 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MED134_RS01295 411bc7e249dbfa2f49286308685437b0 263 Pfam PF12864 Protein of unknown function (DUF3822) 7 242 5.1E-65 T 22-04-2016 IPR024213 Protein of unknown function DUF3822 MED134_RS02715 874ed2cb5a88f378a1c4266c2dd6d789 136 PANTHER PTHR33639 3 132 2.9E-56 T 22-04-2016 MED134_RS02715 874ed2cb5a88f378a1c4266c2dd6d789 136 Pfam PF04134 Protein of unknown function, DUF393 6 115 5.7E-37 T 22-04-2016 IPR007263 Protein of unknown function DUF393 MED134_RS02790 9e2353d57ec2189c9ccb118749e1a554 405 Pfam PF14258 Domain of unknown function (DUF4350) 40 112 2.0E-14 T 22-04-2016 IPR025646 Domain of unknown function DUF4350 MED134_RS07225 73a003aab45c2d2d86749c0dc0ed8208 434 Gene3D G3DSA:2.60.40.1120 39 96 6.4E-7 T 22-04-2016 IPR014766 Carboxypeptidase, regulatory domain MED134_RS07225 73a003aab45c2d2d86749c0dc0ed8208 434 SUPERFAMILY SSF49464 38 120 6.8E-10 T 22-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain MED134_RS07225 73a003aab45c2d2d86749c0dc0ed8208 434 Pfam PF13715 CarboxypepD_reg-like domain 39 120 3.7E-10 T 22-04-2016 MED134_RS12540 f37f6c33c75ea61a63a75516aa75e121 238 Pfam PF03799 Cell division protein FtsQ 117 213 4.9E-5 T 22-04-2016 IPR005548 Cell division protein FtsQ/DivIB MED134_RS07115 d32745d089ff9cc802c5fa5ffb173278 180 PANTHER PTHR13194:SF7 1 177 3.4E-18 T 22-04-2016 MED134_RS07115 d32745d089ff9cc802c5fa5ffb173278 180 SUPERFAMILY SSF49785 28 175 4.17E-17 T 22-04-2016 IPR008979 Galactose-binding domain-like MED134_RS07115 d32745d089ff9cc802c5fa5ffb173278 180 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 21 174 3.9E-27 T 22-04-2016 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 MED134_RS07115 d32745d089ff9cc802c5fa5ffb173278 180 PANTHER PTHR13194 1 177 3.4E-18 T 22-04-2016 MED134_RS04050 a9fec07285a31bad878190df619021b7 418 SUPERFAMILY SSF159501 14 328 1.36E-31 T 22-04-2016 MED134_RS04240 e283ebe7ab79af8de9f2917a4a34ed48 688 Pfam PF03993 Domain of Unknown Function (DUF349) 235 308 2.4E-12 T 22-04-2016 IPR007139 Protein of unknown function DUF349 MED134_RS04240 e283ebe7ab79af8de9f2917a4a34ed48 688 Pfam PF03993 Domain of Unknown Function (DUF349) 312 390 2.6E-11 T 22-04-2016 IPR007139 Protein of unknown function DUF349 MED134_RS04240 e283ebe7ab79af8de9f2917a4a34ed48 688 Pfam PF03993 Domain of Unknown Function (DUF349) 472 542 5.3E-17 T 22-04-2016 IPR007139 Protein of unknown function DUF349 MED134_RS04240 e283ebe7ab79af8de9f2917a4a34ed48 688 Pfam PF03993 Domain of Unknown Function (DUF349) 154 230 4.1E-16 T 22-04-2016 IPR007139 Protein of unknown function DUF349 MED134_RS04240 e283ebe7ab79af8de9f2917a4a34ed48 688 Pfam PF03993 Domain of Unknown Function (DUF349) 395 467 6.9E-19 T 22-04-2016 IPR007139 Protein of unknown function DUF349 MED134_RS14295 ebd769f6f3f98136c780cb3b6eaa7274 791 SUPERFAMILY SSF55781 248 387 4.25E-6 T 22-04-2016 IPR029016 GAF domain-like MED134_RS14295 ebd769f6f3f98136c780cb3b6eaa7274 791 Gene3D G3DSA:3.30.450.40 298 382 2.0E-5 T 22-04-2016 IPR029016 GAF domain-like MED134_RS03635 1f0e2aa1da1b19e626a425cc86f88aba 147 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 35 144 1.3E-39 T 22-04-2016 IPR029464 Type I restriction enzyme R protein, N-terminal domain MED134_RS06035 6cffe90cab1f982261dbca80abd99817 72 ProDom PD058023 TRANSMEMBRANE SO1069 MEMBRANE VCA0743 SO4196 VVA0623 VPA0666 HI1736 PM0424 1 65 5.0E-9 T 22-04-2016 IPR020137 Uncharacterised protein family HI1736 MED134_RS07740 b0d2a046c5621286c966f939eebdd3f4 272 Pfam PF11306 Protein of unknown function (DUF3108) 30 260 4.8E-62 T 22-04-2016 IPR021457 Protein of unknown function DUF3108 MED134_RS13275 3e71e0dc348130690fc0a7a72b8ed42e 155 Pfam PF09537 Domain of unknown function (DUF2383) 9 108 3.8E-9 T 22-04-2016 IPR019052 Domain of unknown function DUF2383 MED134_RS08535 659ee7b4efbbd58c614d6bc37637a063 190 SUPERFAMILY SSF160574 24 176 1.09E-11 T 22-04-2016 MED134_RS08225 ff827e8181ae3b403387b35e2f584539 144 Pfam PF05154 TM2 domain 59 104 5.5E-11 T 22-04-2016 IPR007829 TM2 domain MED134_RS01775 f488b770d9f559613f4173cf070b2eec 1680 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1182 1639 3.1E-85 T 22-04-2016 IPR007452 Translocation and assembly module TamB MED134_RS00050 881a9cf400097f4993fcbc2bfb94ef13 232 Pfam PF14289 Domain of unknown function (DUF4369) 16 119 5.8E-16 T 22-04-2016 IPR025380 Domain of unknown function DUF4369 MED134_RS09210 4b5be0742e9bf43685ad5642e34b8c39 323 Pfam PF16125 Domain of unknown function (DUF4837) 30 319 1.9E-88 T 22-04-2016 IPR032286 Protein of unknown function DUF4837 MED134_RS05940 1d113d28ff88b58aebdc98a68c72c8a9 204 Pfam PF02472 Biopolymer transport protein ExbD/TolR 3 146 8.6E-19 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MED134_RS11915 134faeae2e4ff52f8c90a5e6b4dc3605 198 Pfam PF10263 SprT-like family 28 95 1.4E-8 T 22-04-2016 IPR006640 SprT-like MED134_RS01815 4864fd4e38b9006c02e0b799c1df9dc5 160 Pfam PF13648 Lipocalin-like domain 35 128 9.9E-8 T 22-04-2016 IPR024311 Lipocalin-like domain MED134_RS10170 87f746ef975e160680290df2276fb590 114 Pfam PF05154 TM2 domain 58 104 2.2E-10 T 22-04-2016 IPR007829 TM2 domain MED134_RS04585 94a7158668093841081385af6c98e047 62 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 20 56 9.7E-7 T 22-04-2016 IPR008621 Cbb3-type cytochrome oxidase component MED134_RS03840 af76ade71255b4c3915e2b496aada6ca 315 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 308 1.5E-68 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 MED134_RS03840 af76ade71255b4c3915e2b496aada6ca 315 PANTHER PTHR10846 12 313 9.7E-44 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 MED134_RS03840 af76ade71255b4c3915e2b496aada6ca 315 Pfam PF01699 Sodium/calcium exchanger protein 169 313 2.9E-24 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 MED134_RS03840 af76ade71255b4c3915e2b496aada6ca 315 Pfam PF01699 Sodium/calcium exchanger protein 2 143 2.7E-27 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 MED134_RS07160 30c0e77942dd2c1a7a04a75d5114d023 262 SUPERFAMILY SSF101898 72 191 6.8E-5 T 22-04-2016 MED134_RS07265 90a4b7211df289752adcf538b3a66f9e 148 Pfam PF13239 2TM domain 21 106 1.4E-20 T 22-04-2016 IPR025698 2TM domain MED134_RS09285 15ce8ee291aae6fcb6509d53e2c1970c 407 Pfam PF13579 Glycosyl transferase 4-like domain 23 198 8.5E-8 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain MED134_RS09285 15ce8ee291aae6fcb6509d53e2c1970c 407 Pfam PF13692 Glycosyl transferases group 1 232 369 3.5E-8 T 22-04-2016 MED134_RS09285 15ce8ee291aae6fcb6509d53e2c1970c 407 SUPERFAMILY SSF53756 11 407 6.8E-31 T 22-04-2016 MED134_RS05735 c7c7ebabbb523f8ec2c72faef96a577b 178 Pfam PF11138 Protein of unknown function (DUF2911) 40 176 1.2E-43 T 22-04-2016 IPR021314 Protein of unknown function DUF2911 MED134_RS14575 d0f925740063eda422ff0cd59109d812 425 Pfam PF11013 Protein of unknown function (DUF2851) 3 378 4.5E-143 T 22-04-2016 IPR021272 Protein of unknown function DUF2851 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 614 647 4.2E-8 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 70 95 3.9E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 160 186 1.1E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 664 694 3.9E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 468 490 2.7E-4 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 528 570 2.4E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 555 581 9.4E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 383 416 5.3E-6 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 372 405 2.2E-4 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 270 296 8.2E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 361 394 1.2E-5 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 328 361 1.9E-4 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 405 427 1.7E-4 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS03825 f6aa04ad2b5ff6b54b6078301ef8ff6d 750 Pfam PF07012 Curlin associated repeat 152 182 1.1E-4 T 22-04-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 MED134_RS05395 7c5bdfe73abb6e65021eab22fefd3434 211 Pfam PF08889 WbqC-like protein family 13 149 4.9E-24 T 22-04-2016 IPR014985 WbqC-like protein family MED134_RS00460 cfeb213f4b72ab2956c7190154aa483c 259 Pfam PF03432 Relaxase/Mobilisation nuclease domain 9 239 4.2E-16 T 22-04-2016 IPR005094 Endonuclease relaxase, MobA/VirD2 MED134_RS03810 431010998517bc4c96952a4852291d1e 253 Pfam PF10627 Curli assembly protein CsgE 155 246 2.0E-8 T 22-04-2016 IPR018900 Curli assembly protein CsgE MED134_RS02130 f58b75c33d58901bc90dab618b62fda5 826 Pfam PF05569 BlaR1 peptidase M56 14 261 8.8E-14 T 22-04-2016 IPR008756 Peptidase M56 MED134_RS02130 f58b75c33d58901bc90dab618b62fda5 826 PANTHER PTHR34978 158 286 3.3E-12 T 22-04-2016 MED134_RS10075 5974065e7a9c51fa858716f1ec0ee9d1 140 Pfam PF10504 Protein of unknown function (DUF2452) 57 133 3.0E-12 T 22-04-2016 IPR019534 Protein of unknown function DUF2452 MED134_RS06120 3267411fb3b2a65cfeef8ff98b090aa0 311 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 37 307 7.5E-44 T 22-04-2016 IPR018707 Protein of unknown function DUF2219 MED134_RS06120 3267411fb3b2a65cfeef8ff98b090aa0 311 Gene3D G3DSA:2.40.128.140 25 306 1.6E-46 T 22-04-2016 MED134_RS03805 c67ff5b17f8e80665c98858cbf817e2a 135 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 11 134 1.6E-42 T 22-04-2016 IPR018893 Type VIII secretion system, CsgF MED134_RS09800 3c0ee93a186aca381c139cbb0e7a810d 280 Gene3D G3DSA:2.40.160.20 207 275 8.6E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS09800 3c0ee93a186aca381c139cbb0e7a810d 280 Gene3D G3DSA:2.40.160.20 145 172 8.6E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS13470 e2706e648e99298a164eb875f42ce919 441 Pfam PF04932 O-Antigen ligase 235 373 1.6E-11 T 22-04-2016 IPR007016 O-antigen ligase-related MED134_RS01020 e60b083c23d6fe8b5ce4dc4225186516 219 Pfam PF13568 Outer membrane protein beta-barrel domain 21 170 6.4E-13 T 22-04-2016 IPR025665 Outer membrane protein beta-barrel domain MED134_RS08810 74c83f7522aed921689b03eec8c088f9 481 SUPERFAMILY SSF56925 365 481 4.45E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MED134_RS10835 0c953b906cc07bde055dfbf1f38bb5e9 318 Pfam PF11276 Protein of unknown function (DUF3078) 42 135 1.1E-28 T 22-04-2016 IPR021428 Protein of unknown function DUF3078 MED134_RS03385 5a0e5ebb17b65eaafa24113e1d627f20 164 Pfam PF03692 Putative zinc- or iron-chelating domain 50 137 5.3E-15 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein MED134_RS01895 1cdff24061cf5ae815640f84257dc273 1098 Pfam PF07705 CARDB 522 606 6.2E-7 T 22-04-2016 IPR011635 CARDB domain MED134_RS08155 1c5eb0cf3c6da8d35d67b65e2691485d 197 Pfam PF13795 HupE / UreJ protein 7 161 2.0E-46 T 22-04-2016 IPR032809 Putative HupE/UreJ protein MED134_RS10730 45c9f8be2e00209e41c5fff515daf402 155 Pfam PF14129 Domain of unknown function (DUF4296) 16 96 2.5E-13 T 22-04-2016 IPR025381 Domain of unknown function DUF4296 MED134_RS04970 85ed620a141fa7ac08e1ebf7f9125df8 294 Pfam PF12836 Helix-hairpin-helix motif 232 291 1.8E-13 T 22-04-2016 MED134_RS04970 85ed620a141fa7ac08e1ebf7f9125df8 294 Gene3D G3DSA:1.10.150.310 236 294 2.8E-7 T 22-04-2016 IPR023097 Tex RuvX-like domain MED134_RS04970 85ed620a141fa7ac08e1ebf7f9125df8 294 SUPERFAMILY SSF47781 221 293 5.04E-14 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 MED134_RS04970 85ed620a141fa7ac08e1ebf7f9125df8 294 Gene3D G3DSA:1.10.150.280 148 215 2.0E-4 T 22-04-2016 MED134_RS11885 77b57b480a29222daea88b0dc3fc0a03 396 Gene3D G3DSA:2.40.160.60 37 211 1.8E-10 T 22-04-2016 MED134_RS11885 77b57b480a29222daea88b0dc3fc0a03 396 Gene3D G3DSA:2.40.160.60 316 375 4.3E-7 T 22-04-2016 MED134_RS00940 8c9f3fe140556d4077c98be315dbebd0 397 Pfam PF07766 LETM1-like protein 316 394 1.4E-11 T 22-04-2016 IPR011685 LETM1-like MED134_RS09100 72ed04076d65382f1181a44ac14d7755 223 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 28 207 1.7E-39 T 22-04-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain MED134_RS14185 9ac621c7d7260bef95d3d8df812cfb09 373 Pfam PF09375 Imelysin 51 331 1.0E-28 T 22-04-2016 MED134_RS04395 f3e7b6b2f1513167ff9568d9ea91929c 134 Pfam PF14248 Domain of unknown function (DUF4345) 6 121 4.6E-23 T 22-04-2016 IPR025597 Protein of unknown function DUF4345 MED134_RS02015 21673682f1cfb5eca6736d11ab300280 254 Pfam PF09674 Protein of unknown function (DUF2400) 26 250 9.8E-84 T 22-04-2016 IPR014127 Conserved hypothetical protein CHP02757 MED134_RS02015 21673682f1cfb5eca6736d11ab300280 254 TIGRFAM TIGR02757 TIGR02757: TIGR02757 family protein 22 249 1.4E-68 T 22-04-2016 IPR014127 Conserved hypothetical protein CHP02757 MED134_RS12465 59fc416025a2ca58706515154ebb18ad 325 TIGRFAM TIGR03514 GldB_lipo: gliding motility-associated lipoprotein GldB 16 325 1.6E-99 T 22-04-2016 IPR019853 Gliding motility-associated lipoprotein, GldB MED134_RS04085 b4099ae691bc2f721009485e965526bd 186 Pfam PF06271 RDD family 25 167 2.2E-10 T 22-04-2016 IPR010432 RDD MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 1000 1034 1.6E-10 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 694 717 1.7E-7 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 606 640 1.6E-12 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 1075 1110 2.4E-6 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 529 564 1.3E-12 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 922 958 1.3E-7 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 453 486 3.0E-14 T 22-04-2016 IPR025667 SprB repeat MED134_RS14600 769cb68a0b158098d6c631e11a972d97 2205 Pfam PF13573 SprB repeat 847 881 6.0E-9 T 22-04-2016 IPR025667 SprB repeat MED134_RS01045 2db6de246730b5b14f6650fbf5344d55 1471 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1006 1430 5.3E-76 T 22-04-2016 IPR007452 Translocation and assembly module TamB MED134_RS01600 95d271253a5fa8b791d40e5dfd4833ea 281 Gene3D G3DSA:1.10.760.10 7 109 1.3E-4 T 22-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 MED134_RS01600 95d271253a5fa8b791d40e5dfd4833ea 281 SUPERFAMILY SSF101874 139 277 6.67E-5 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MED134_RS02990 d67490f8af20a6379a96d261b8d3c2fd 211 Pfam PF06078 Bacterial protein of unknown function (DUF937) 6 140 1.1E-36 T 22-04-2016 IPR009282 Protein of unknown function DUF937 MED134_RS09930 7852c739ac7dd74f4e68e5c4fd3fb40c 588 Pfam PF13584 Oxygen tolerance 16 499 5.6E-147 T 22-04-2016 IPR025738 Aerotolerance-related protein BatD MED134_RS07925 3ff161c7ad71f535a8afabf63c2de046 147 Pfam PF08695 Cytochrome oxidase complex assembly protein 1 31 139 1.8E-11 T 22-04-2016 IPR014807 Cytochrome oxidase assembly protein 1 MED134_RS14610 077917166f19267d0f59fa65c2e13c05 232 Pfam PF07799 Protein of unknown function (DUF1643) 59 197 7.3E-19 T 22-04-2016 IPR012441 Protein of unknown function DUF1643 MED134_RS13820 31d53e66be0d5ca7b3c698c9c0a4e08b 226 Pfam PF14127 Domain of unknown function (DUF4294) 39 195 6.9E-62 T 22-04-2016 IPR025636 Protein of unknown function DUF4294 MED134_RS09390 d03cecc536210f8b99c222d70ef0807d 71 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 13 64 7.7E-10 T 22-04-2016 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter