locus-tag	class	description
BSK21_RS00030	COG0564	pseudouridine synthase activity
BSK21_RS00040	COG0450	alkyl hydroperoxide reductase
BSK21_RS00045	COG4067	protein conserved in archaea
BSK21_RS00045	COG0189	ligase activity
BSK21_RS00050	COG0189	ligase activity
BSK21_RS00065	COG1185	polyribonucleotide nucleotidyltransferase activity
BSK21_RS00070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSK21_RS00090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSK21_RS00100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSK21_RS00105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSK21_RS00115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSK21_RS00115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSK21_RS00125	COG0138	bifunctional purine biosynthesis protein purh
BSK21_RS00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSK21_RS00140	COG0612	Peptidase, M16
BSK21_RS00145	COG0612	Peptidase, M16
BSK21_RS00150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSK21_RS00160	COG3806	Anti-sigma factor
BSK21_RS00165	COG1595	DNA-templated transcription, initiation
BSK21_RS00170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BSK21_RS00185	COG0300	oxidoreductase activity
BSK21_RS00200	COG0347	Belongs to the P(II) protein family
BSK21_RS00205	COG0004	ammonium transporteR
BSK21_RS00215	COG2897	thiosulfate sulfurtransferase activity
BSK21_RS00220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSK21_RS00230	COG0697	spore germination
BSK21_RS00235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSK21_RS00260	COG1304	FMN binding
BSK21_RS00315	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK21_RS00315	COG3409	Peptidoglycan-binding domain 1 protein
BSK21_RS00320	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BSK21_RS00335	COG0435	Glutathione S-transferase
BSK21_RS00380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BSK21_RS00385	COG0242	peptide deformylase activity
BSK21_RS00390	COG0242	peptide deformylase activity
BSK21_RS00395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSK21_RS00400	COG2860	membrane
BSK21_RS00435	COG0842	Transport permease protein
BSK21_RS00440	COG1129	ABC transporter
BSK21_RS00440	COG0842	Transport permease protein
BSK21_RS00445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSK21_RS00450	COG1611	Belongs to the LOG family
BSK21_RS00455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSK21_RS00460	COG1309	transcriptional regulator
BSK21_RS00495	COG2223	nitrite transmembrane transporter activity
BSK21_RS00500	COG2223	nitrite transmembrane transporter activity
BSK21_RS00505	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BSK21_RS00510	COG1140	nitrate reductase beta subunit
BSK21_RS00515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BSK21_RS00520	COG2181	nitrate reductase activity
BSK21_RS00530	COG0288	reversible hydration of carbon dioxide
BSK21_RS00535	COG0303	'Molybdopterin
BSK21_RS00540	COG1618	nucleotide phosphatase activity, acting on free nucleotides
BSK21_RS00540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSK21_RS00570	COG2207	Transcriptional regulator
BSK21_RS00585	COG0582	viral genome integration into host DNA
BSK21_RS00615	COG4948	Mandelate Racemase Muconate Lactonizing
BSK21_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK21_RS00640	COG1737	Transcriptional regulator
BSK21_RS00645	COG4974	Belongs to the 'phage' integrase family
BSK21_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
BSK21_RS00685	COG3848	Pyruvate phosphate dikinase
BSK21_RS00685	COG0574	Belongs to the PEP-utilizing enzyme family
BSK21_RS00700	COG0583	DNA-binding transcription factor activity
BSK21_RS00710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSK21_RS00720	COG3485	protocatechuate 3,4-dioxygenase
BSK21_RS00725	COG3485	protocatechuate 3,4-dioxygenase
BSK21_RS00730	COG3246	L-lysine catabolic process to acetate
BSK21_RS00735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSK21_RS00760	COG0012	GTP binding
BSK21_RS00770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSK21_RS00775	COG1183	phosphatidylcholine synthase activity
BSK21_RS00785	COG0513	Belongs to the DEAD box helicase family
BSK21_RS00790	COG0193	aminoacyl-tRNA hydrolase activity
BSK21_RS00820	COG0133	tryptophan synthase activity
BSK21_RS00825	COG0135	phosphoribosylanthranilate isomerase activity
BSK21_RS00835	COG0776	regulation of translation
BSK21_RS00840	COG0539	negative regulation of cytoplasmic translation
BSK21_RS00845	COG0778	Nitroreductase
BSK21_RS00850	COG1733	regulation of RNA biosynthetic process
BSK21_RS00860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSK21_RS00865	COG0813	purine-nucleoside phosphorylase activity
BSK21_RS00875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSK21_RS00875	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSK21_RS00885	COG0604	alcohol dehydrogenase
BSK21_RS00905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSK21_RS00915	COG0730	response to heat
BSK21_RS00920	COG0328	RNA-DNA hybrid ribonuclease activity
BSK21_RS00930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSK21_RS00940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSK21_RS00945	COG1758	RNA polymerase activity
BSK21_RS00950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSK21_RS00960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSK21_RS00965	COG0736	holo-[acyl-carrier-protein] synthase activity
BSK21_RS00970	COG0681	Belongs to the peptidase S26 family
BSK21_RS00975	COG0681	Belongs to the peptidase S26 family
BSK21_RS00980	COG0571	ribonuclease III activity
BSK21_RS00985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSK21_RS01000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK21_RS01010	COG1660	Displays ATPase and GTPase activities
BSK21_RS01020	COG2205	protein histidine kinase activity
BSK21_RS01025	COG0745	RESPONSE REGULATOR receiver
BSK21_RS01030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSK21_RS01050	COG1381	Involved in DNA repair and RecF pathway recombination
BSK21_RS01055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK21_RS01085	COG0300	oxidoreductase activity
BSK21_RS01090	COG4991	sh3 domain protein
BSK21_RS01095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSK21_RS01105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSK21_RS01130	COG0250	Participates in transcription elongation, termination and antitermination
BSK21_RS01135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSK21_RS01140	COG0081	regulation of translation
BSK21_RS01145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSK21_RS01150	COG0222	ribosome binding
BSK21_RS01155	COG0085	RNA polymerase activity
BSK21_RS01160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSK21_RS01165	COG0697	spore germination
BSK21_RS01175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSK21_RS01180	COG0049	tRNA binding
BSK21_RS01185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSK21_RS01190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSK21_RS01195	COG0051	transcription antitermination factor activity, RNA binding
BSK21_RS01200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSK21_RS01205	COG0088	Forms part of the polypeptide exit tunnel
BSK21_RS01210	COG0089	rRNA binding
BSK21_RS01215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSK21_RS01220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSK21_RS01225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSK21_RS01230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSK21_RS01235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSK21_RS01245	COG0255	Belongs to the universal ribosomal protein uL29 family
BSK21_RS01250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSK21_RS01260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSK21_RS01265	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSK21_RS01270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSK21_RS01275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSK21_RS01280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSK21_RS01285	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSK21_RS01290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSK21_RS01295	COG1841	ribosomal large subunit assembly
BSK21_RS01305	COG0200	Binds to the 23S rRNA
BSK21_RS01315	COG0563	adenylate kinase activity
BSK21_RS01320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSK21_RS01325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSK21_RS01330	COG0202	RNA polymerase activity
BSK21_RS01350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSK21_RS01365	COG0546	phosphoglycolate phosphatase activity
BSK21_RS01375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK21_RS01380	COG4597	amino acid ABC transporter
BSK21_RS01385	COG0765	amino acid transport
BSK21_RS01390	COG1126	abc transporter atp-binding protein
BSK21_RS01405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSK21_RS01410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSK21_RS01415	COG0706	membrane insertase activity
BSK21_RS01420	COG3300	MHYT domain
BSK21_RS01420	COG5001	Diguanylate cyclase
BSK21_RS01425	COG0037	tRNA processing
BSK21_RS01430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSK21_RS01435	COG0594	ribonuclease P activity
BSK21_RS01440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSK21_RS01450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSK21_RS01455	COG5002	protein histidine kinase activity
BSK21_RS01545	COG1397	ADP-ribosylglycohydrolase
BSK21_RS01595	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BSK21_RS01595	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BSK21_RS01645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSK21_RS01670	COG0745	RESPONSE REGULATOR receiver
BSK21_RS01680	COG0835	chemotaxis
BSK21_RS01690	COG0835	chemotaxis
BSK21_RS01695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSK21_RS01700	COG2201	protein-glutamate methylesterase activity
BSK21_RS01710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSK21_RS01730	COG0129	dihydroxy-acid dehydratase activity
BSK21_RS01740	COG0159	tryptophan synthase activity
BSK21_RS01745	COG1131	(ABC) transporter
BSK21_RS01750	COG0842	Transport permease protein
BSK21_RS01755	COG0616	signal peptide processing
BSK21_RS01755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSK21_RS01770	COG0322	excinuclease ABC activity
BSK21_RS01775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSK21_RS01785	COG0314	molybdopterin synthase activity
BSK21_RS01790	COG3300	MHYT domain
BSK21_RS01790	COG5001	Diguanylate cyclase
BSK21_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS01815	COG2890	protein-(glutamine-N5) methyltransferase activity
BSK21_RS01825	COG0142	geranyltranstransferase activity
BSK21_RS01830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSK21_RS01845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSK21_RS01885	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS01890	COG0009	L-threonylcarbamoyladenylate synthase
BSK21_RS01900	COG2885	chlorophyll binding
BSK21_RS01905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSK21_RS01910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSK21_RS01925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSK21_RS01940	COG0540	Belongs to the ATCase OTCase family
BSK21_RS01950	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSK21_RS01960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSK21_RS01970	COG1678	Uncharacterized ACR, COG1678
BSK21_RS01975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK21_RS01980	COG0165	Argininosuccinate lyase
BSK21_RS01990	COG0019	diaminopimelate decarboxylase activity
BSK21_RS02005	COG2884	Cell division ATP-binding protein ftsE
BSK21_RS02025	COG0825	malonyl-CoA metabolic process
BSK21_RS02055	COG0469	pyruvate kinase activity
BSK21_RS02065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSK21_RS02070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSK21_RS02075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSK21_RS02080	COG0072	phenylalanine-tRNA ligase activity
BSK21_RS02080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK21_RS02095	COG0077	Prephenate dehydratase
BSK21_RS02095	COG1605	Chorismate mutase
BSK21_RS02105	COG4166	transmembrane transport
BSK21_RS02110	COG4174	ABC transporter (Permease)
BSK21_RS02115	COG4239	(ABC) transporter, permease
BSK21_RS02125	COG1686	Belongs to the peptidase S11 family
BSK21_RS02135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSK21_RS02140	COG2813	Specifically methylates the guanine in position
BSK21_RS02155	COG0408	coproporphyrinogen oxidase activity
BSK21_RS02160	COG1280	lysine exporter protein (LysE YggA)
BSK21_RS02165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSK21_RS02170	COG0181	hydroxymethylbilane synthase activity
BSK21_RS02180	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSK21_RS02190	COG2217	Heavy metal translocating P-type atpase
BSK21_RS02200	COG3257	ureidoglycine aminohydrolase activity
BSK21_RS02215	COG0443	Heat shock 70 kDa protein
BSK21_RS02220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK21_RS02235	COG2197	response regulator
BSK21_RS02250	COG1558	bacterial-type flagellum-dependent cell motility
BSK21_RS02255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BSK21_RS02270	COG4786	Flagellar basal body rod
BSK21_RS02285	COG1522	sequence-specific DNA binding
BSK21_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
BSK21_RS02295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK21_RS02300	COG1234	tRNA 3'-trailer cleavage
BSK21_RS02305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSK21_RS02315	COG3046	protein related to deoxyribodipyrimidine photolyase
BSK21_RS02330	COG3128	pkhd-type hydroxylase
BSK21_RS02345	COG1278	Cold shock
BSK21_RS02350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSK21_RS02355	COG3118	belongs to the thioredoxin family
BSK21_RS02375	COG3383	formate dehydrogenase (NAD+) activity
BSK21_RS02380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSK21_RS02420	COG0375	protein maturation
BSK21_RS02470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BSK21_RS02480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BSK21_RS02490	COG4191	Histidine kinase
BSK21_RS02495	COG0489	protein tyrosine kinase activity
BSK21_RS02495	COG2151	metal-sulfur cluster biosynthetic enzyme
BSK21_RS02500	COG0513	Belongs to the DEAD box helicase family
BSK21_RS02505	COG0254	rRNA binding
BSK21_RS02510	COG0335	large ribosomal subunit rRNA binding
BSK21_RS02520	COG0336	Belongs to the RNA methyltransferase TrmD family
BSK21_RS02530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSK21_RS02535	COG0778	Nitroreductase
BSK21_RS02560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSK21_RS02585	COG0356	it plays a direct role in the translocation of protons across the membrane
BSK21_RS02590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSK21_RS02595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSK21_RS02600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSK21_RS02610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSK21_RS02615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK21_RS02625	COG1234	tRNA 3'-trailer cleavage
BSK21_RS02630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSK21_RS02635	COG0738	Major facilitator superfamily
BSK21_RS02650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSK21_RS02660	COG1703	isobutyryl-CoA mutase activity
BSK21_RS02670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSK21_RS02675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK21_RS02685	COG0174	glutamine synthetase
BSK21_RS02690	COG0519	Catalyzes the synthesis of GMP from XMP
BSK21_RS02690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSK21_RS02695	COG0174	glutamine synthetase
BSK21_RS02705	COG4215	(ABC) transporter
BSK21_RS02725	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSK21_RS02730	COG0504	CTP synthase activity
BSK21_RS02740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSK21_RS02760	COG0697	spore germination
BSK21_RS02765	COG1760	l-serine dehydratase
BSK21_RS02770	COG0625	glutathione transferase activity
BSK21_RS02775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSK21_RS02790	COG0330	HflC and HflK could
BSK21_RS02800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSK21_RS02820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BSK21_RS02825	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSK21_RS02830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSK21_RS02830	COG0475	glutathione-regulated potassium exporter activity
BSK21_RS02840	COG2968	Membrane
BSK21_RS02845	COG2873	o-acetylhomoserine
BSK21_RS02865	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSK21_RS02870	COG1131	(ABC) transporter
BSK21_RS02885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK21_RS02885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK21_RS02890	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK21_RS02920	COG0714	Associated with various cellular activities
BSK21_RS02950	COG0604	alcohol dehydrogenase
BSK21_RS02960	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSK21_RS02970	COG0686	Belongs to the AlaDH PNT family
BSK21_RS02975	COG1970	mechanosensitive ion channel activity
BSK21_RS02980	COG0625	glutathione transferase activity
BSK21_RS02985	COG0463	Glycosyl transferase, family 2
BSK21_RS03000	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSK21_RS03050	COG1376	ErfK ybiS ycfS ynhG family protein
BSK21_RS03080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSK21_RS03110	COG0069	glutamate synthase activity
BSK21_RS03120	COG0642	Histidine kinase
BSK21_RS03190	COG3206	protein involved in exopolysaccharide biosynthesis
BSK21_RS03190	COG0489	protein tyrosine kinase activity
BSK21_RS03200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSK21_RS03215	COG1492	cobalamin metabolic process
BSK21_RS03225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSK21_RS03230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSK21_RS03240	COG1132	(ABC) transporter
BSK21_RS03245	COG0354	folic acid binding
BSK21_RS03250	COG0318	PFAM AMP-dependent synthetase and ligase
BSK21_RS03255	COG0525	valine-tRNA ligase activity
BSK21_RS03275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSK21_RS03280	COG0583	DNA-binding transcription factor activity
BSK21_RS03290	COG0483	inositol monophosphate 1-phosphatase activity
BSK21_RS03295	COG1522	sequence-specific DNA binding
BSK21_RS03350	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS03370	COG0033	Phosphoglucomutase
BSK21_RS03375	COG1072	(Pantothenic acid kinase))
BSK21_RS03405	COG1295	ribonuclease BN
BSK21_RS03420	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BSK21_RS03425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSK21_RS03430	COG0740	serine-type endopeptidase activity
BSK21_RS03440	COG0251	oxidation-reduction process
BSK21_RS03465	COG0439	Biotin carboxylase
BSK21_RS03470	COG0511	ligase activity, forming carbon-carbon bonds
BSK21_RS03475	COG0410	ABC transporter
BSK21_RS03500	COG1396	sequence-specific DNA binding
BSK21_RS03500	COG3800	Transcriptional regulator
BSK21_RS03505	COG0745	RESPONSE REGULATOR receiver
BSK21_RS03535	COG2391	methyltransferase activity
BSK21_RS03550	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK21_RS03550	COG1024	Enoyl-CoA hydratase
BSK21_RS03560	COG3750	Belongs to the UPF0335 family
BSK21_RS03660	COG0829	nickel cation binding
BSK21_RS03665	COG0831	urea catabolic process
BSK21_RS03670	COG0832	Belongs to the urease beta subunit family
BSK21_RS03675	COG0804	urea catabolic process
BSK21_RS03680	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BSK21_RS03690	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSK21_RS03700	COG0824	Thioesterase
BSK21_RS03725	COG2885	chlorophyll binding
BSK21_RS03735	COG0037	tRNA processing
BSK21_RS03740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSK21_RS03755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BSK21_RS03760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSK21_RS03770	COG1201	RNA secondary structure unwinding
BSK21_RS03775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSK21_RS03785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSK21_RS03790	COG1832	CoA-binding protein
BSK21_RS03800	COG0156	8-amino-7-oxononanoate synthase activity
BSK21_RS03810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSK21_RS03815	COG0493	'glutamate synthase
BSK21_RS03840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSK21_RS03845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSK21_RS03850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSK21_RS03855	COG0140	phosphoribosyl-ATP diphosphatase activity
BSK21_RS03860	COG0107	imidazoleglycerol-phosphate synthase activity
BSK21_RS03875	COG1278	Cold shock
BSK21_RS03890	COG2084	Dehydrogenase
BSK21_RS03900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSK21_RS03915	COG0154	amidase activity
BSK21_RS03925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSK21_RS03930	COG1414	Transcriptional regulator
BSK21_RS03935	COG0277	FAD linked oxidase domain protein
BSK21_RS03940	COG0277	FAD linked oxidase domain protein
BSK21_RS03945	COG0247	lactate metabolic process
BSK21_RS03950	COG4221	oxidoreductase activity
BSK21_RS03960	COG0481	GTPase activity
BSK21_RS03980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSK21_RS03985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSK21_RS03990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSK21_RS04000	COG0281	malic enzyme
BSK21_RS04000	COG0280	phosphate acetyltransferase
BSK21_RS04005	COG0295	cytidine deaminase activity
BSK21_RS04010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSK21_RS04015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BSK21_RS04020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSK21_RS04025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSK21_RS04060	COG1024	Enoyl-CoA hydratase
BSK21_RS04060	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK21_RS04065	COG0183	Belongs to the thiolase family
BSK21_RS04070	COG0625	glutathione transferase activity
BSK21_RS04075	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS04100	COG0534	Mate efflux family protein
BSK21_RS04105	COG1393	Belongs to the ArsC family
BSK21_RS04110	COG0167	dihydroorotate dehydrogenase activity
BSK21_RS04120	COG0737	Belongs to the 5'-nucleotidase family
BSK21_RS04130	COG2135	peptidase activity
BSK21_RS04140	COG1132	(ABC) transporter
BSK21_RS04150	COG2824	Alkylphosphonate utilization operon protein PhnA
BSK21_RS04160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSK21_RS04170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSK21_RS04175	COG0131	Imidazoleglycerol-phosphate dehydratase
BSK21_RS04190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSK21_RS04215	COG1279	arginine transmembrane transporter activity
BSK21_RS04225	COG0489	protein tyrosine kinase activity
BSK21_RS04230	COG2001	Belongs to the MraZ family
BSK21_RS04235	COG0275	rRNA processing
BSK21_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSK21_RS04260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSK21_RS04265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSK21_RS04270	COG2081	HI0933 family
BSK21_RS04280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSK21_RS04285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSK21_RS04295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSK21_RS04300	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSK21_RS04305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSK21_RS04310	COG0849	cell division
BSK21_RS04315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSK21_RS04325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSK21_RS04330	COG0497	DNA recombination
BSK21_RS04370	COG0484	heat shock protein binding
BSK21_RS04385	COG3474	cytochrome
BSK21_RS04390	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BSK21_RS04400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSK21_RS04415	COG0308	aminopeptidase N
BSK21_RS04430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BSK21_RS04440	COG2010	Cytochrome c
BSK21_RS04440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSK21_RS04465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BSK21_RS04475	COG0019	diaminopimelate decarboxylase activity
BSK21_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK21_RS04490	COG0601	transmembrane transport
BSK21_RS04495	COG0747	negative chemotaxis
BSK21_RS04500	COG4608	Belongs to the ABC transporter superfamily
BSK21_RS04505	COG0444	Belongs to the ABC transporter superfamily
BSK21_RS04510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK21_RS04515	COG1473	amidohydrolase
BSK21_RS04530	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS04550	COG2089	acid synthase
BSK21_RS04560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSK21_RS04585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSK21_RS04590	COG0546	phosphoglycolate phosphatase activity
BSK21_RS04605	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS04610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSK21_RS04635	COG1024	Enoyl-CoA hydratase
BSK21_RS04650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSK21_RS04655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSK21_RS04665	COG0649	NAD binding
BSK21_RS04680	COG3743	rRNA binding
BSK21_RS04680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSK21_RS04720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSK21_RS04725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSK21_RS04740	COG0713	ATP synthesis coupled electron transport
BSK21_RS04755	COG1007	ATP synthesis coupled electron transport
BSK21_RS04765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSK21_RS04775	COG0513	Belongs to the DEAD box helicase family
BSK21_RS04780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSK21_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS04800	COG3842	ATPase activity
BSK21_RS04805	COG2378	regulation of single-species biofilm formation
BSK21_RS04810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSK21_RS04815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSK21_RS04820	COG0805	protein transport
BSK21_RS04840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSK21_RS04845	COG4221	oxidoreductase activity
BSK21_RS04855	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSK21_RS04880	COG1127	ABC transporter
BSK21_RS04885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSK21_RS04890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSK21_RS04895	COG0305	Participates in initiation and elongation during chromosome replication
BSK21_RS04900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSK21_RS04905	COG0418	dihydroorotase activity
BSK21_RS04920	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSK21_RS04930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSK21_RS04960	COG0436	Aminotransferase
BSK21_RS04965	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK21_RS04975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSK21_RS04980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSK21_RS04995	COG0739	heme binding
BSK21_RS05000	COG2833	Protein of unknown function (DUF455)
BSK21_RS05005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSK21_RS05015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSK21_RS05030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSK21_RS05040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSK21_RS05055	COG1024	Enoyl-CoA hydratase
BSK21_RS05060	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS05080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSK21_RS05090	COG0488	(ABC) transporter
BSK21_RS05095	COG1840	ABC-type Fe3 transport system, periplasmic component
BSK21_RS05100	COG3956	TIGRFAM MazG family protein
BSK21_RS05105	COG1473	amidohydrolase
BSK21_RS05110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSK21_RS05115	COG2818	Glycosylase
BSK21_RS05125	COG2890	protein-(glutamine-N5) methyltransferase activity
BSK21_RS05130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSK21_RS05140	COG0010	Belongs to the arginase family
BSK21_RS05145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSK21_RS05155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSK21_RS05170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSK21_RS05190	COG2095	MarC family integral membrane protein
BSK21_RS05195	COG0488	(ABC) transporter
BSK21_RS05200	COG0105	UTP biosynthetic process
BSK21_RS05210	COG5002	protein histidine kinase activity
BSK21_RS05210	COG2198	Histidine kinase
BSK21_RS05210	COG0784	Response regulator, receiver
BSK21_RS05225	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS05240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSK21_RS05260	COG0028	Belongs to the TPP enzyme family
BSK21_RS05290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSK21_RS05300	COG0800	Aldolase
BSK21_RS05305	COG0129	dihydroxy-acid dehydratase activity
BSK21_RS05325	COG0501	Belongs to the peptidase M48B family
BSK21_RS05365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSK21_RS05380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSK21_RS05395	COG0018	arginyl-trna synthetase
BSK21_RS05405	COG1472	Belongs to the glycosyl hydrolase 3 family
BSK21_RS05410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSK21_RS05415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSK21_RS05430	COG0717	Belongs to the dCTP deaminase family
BSK21_RS05450	COG0776	regulation of translation
BSK21_RS05455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK21_RS05460	COG0416	fatty acid biosynthetic process
BSK21_RS05465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSK21_RS05485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSK21_RS05500	COG0175	sulfate reduction
BSK21_RS05505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSK21_RS05515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSK21_RS05515	COG1648	precorrin-2 dehydrogenase activity
BSK21_RS05520	COG1522	sequence-specific DNA binding
BSK21_RS05525	COG2124	cytochrome p450
BSK21_RS05540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSK21_RS05545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSK21_RS05550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSK21_RS05555	COG0149	triose-phosphate isomerase activity
BSK21_RS05565	COG0316	Belongs to the HesB IscA family
BSK21_RS05570	COG2151	metal-sulfur cluster biosynthetic enzyme
BSK21_RS05585	COG0343	queuine tRNA-ribosyltransferase activity
BSK21_RS05605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSK21_RS05610	COG0776	regulation of translation
BSK21_RS05620	COG0406	alpha-ribazole phosphatase activity
BSK21_RS05635	COG4988	ABC transporter
BSK21_RS05640	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BSK21_RS05650	COG1294	oxidase, subunit
BSK21_RS05665	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS05695	COG2828	Protein conserved in bacteria
BSK21_RS05705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSK21_RS05715	COG1802	Transcriptional regulator
BSK21_RS05720	COG1053	succinate dehydrogenase
BSK21_RS05720	COG3976	FMN-binding domain protein
BSK21_RS05735	COG2205	protein histidine kinase activity
BSK21_RS05825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSK21_RS05845	COG3811	Belongs to the UPF0386 family
BSK21_RS05860	COG2197	response regulator
BSK21_RS05865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK21_RS05870	COG0318	PFAM AMP-dependent synthetase and ligase
BSK21_RS05880	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BSK21_RS05890	COG2223	nitrite transmembrane transporter activity
BSK21_RS05895	COG5002	protein histidine kinase activity
BSK21_RS05900	COG2204	response regulator
BSK21_RS05925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSK21_RS05925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSK21_RS05930	COG2072	flavoprotein involved in K transport
BSK21_RS05935	COG4638	Rieske (2fe-2S)
BSK21_RS05960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK21_RS05965	COG3842	ATPase activity
BSK21_RS05970	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSK21_RS05975	COG1177	transmembrane transport
BSK21_RS05980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BSK21_RS05990	COG4681	YaeQ
BSK21_RS06005	COG1473	amidohydrolase
BSK21_RS06015	COG1024	Enoyl-CoA hydratase
BSK21_RS06030	COG0174	glutamine synthetase
BSK21_RS06035	COG0826	peptidase U32
BSK21_RS06055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSK21_RS06060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSK21_RS06075	COG1217	gtp-binding protein TYPA
BSK21_RS06095	COG0538	isocitrate dehydrogenase activity
BSK21_RS06110	COG2945	thiolester hydrolase activity
BSK21_RS06115	COG1959	2 iron, 2 sulfur cluster binding
BSK21_RS06125	COG0719	Fe-S assembly protein
BSK21_RS06130	COG0396	ATPase activity
BSK21_RS06135	COG0719	Fe-S assembly protein
BSK21_RS06145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSK21_RS06170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSK21_RS06175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSK21_RS06180	COG0215	cysteine-tRNA ligase activity
BSK21_RS06185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSK21_RS06195	COG2814	Major facilitator Superfamily
BSK21_RS06200	COG1797	cobyrinic acid a,c-diamide synthase activity
BSK21_RS06210	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BSK21_RS06215	COG2099	Precorrin-6x reductase
BSK21_RS06235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSK21_RS06240	COG0363	glucosamine-6-phosphate deaminase activity
BSK21_RS06250	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSK21_RS06265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSK21_RS06270	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSK21_RS06275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSK21_RS06280	COG2423	ornithine cyclodeaminase activity
BSK21_RS06285	COG0010	Belongs to the arginase family
BSK21_RS06295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BSK21_RS06300	COG1238	metal cluster binding
BSK21_RS06305	COG2321	neutral zinc metallopeptidase
BSK21_RS06360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSK21_RS06380	COG4166	transmembrane transport
BSK21_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS06400	COG2313	pseudouridylate synthase activity
BSK21_RS06420	COG0052	Belongs to the universal ribosomal protein uS2 family
BSK21_RS06425	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSK21_RS06430	COG2197	response regulator
BSK21_RS06440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSK21_RS06450	COG0006	proline dipeptidase activity
BSK21_RS06455	COG0745	RESPONSE REGULATOR receiver
BSK21_RS06460	COG0704	Plays a role in the regulation of phosphate uptake
BSK21_RS06465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSK21_RS06470	COG0581	inorganic phosphate transmembrane transporter activity
BSK21_RS06475	COG0573	inorganic phosphate transmembrane transporter activity
BSK21_RS06485	COG5002	protein histidine kinase activity
BSK21_RS06500	COG0194	GDP metabolic process
BSK21_RS06505	COG1561	YicC-like family, N-terminal region
BSK21_RS06515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSK21_RS06555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSK21_RS06560	COG1923	regulation of RNA biosynthetic process
BSK21_RS06570	COG0569	domain protein
BSK21_RS06580	COG2204	response regulator
BSK21_RS06585	COG5000	phosphorelay sensor kinase activity
BSK21_RS06590	COG2204	response regulator
BSK21_RS06595	COG3852	Histidine kinase
BSK21_RS06600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSK21_RS06605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSK21_RS06605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSK21_RS06620	COG0004	ammonium transporteR
BSK21_RS06625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSK21_RS06630	COG2867	negative regulation of translational initiation
BSK21_RS06665	COG0519	Catalyzes the synthesis of GMP from XMP
BSK21_RS06665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSK21_RS06690	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSK21_RS06695	COG2326	polyphosphate kinase activity
BSK21_RS06700	COG1309	transcriptional regulator
BSK21_RS06710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSK21_RS06730	COG1024	Enoyl-CoA hydratase
BSK21_RS06735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BSK21_RS06740	COG1612	heme a metabolic process
BSK21_RS06745	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BSK21_RS06750	COG0352	thiamine-phosphate diphosphorylase activity
BSK21_RS06775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSK21_RS06780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSK21_RS06785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSK21_RS06795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSK21_RS06800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSK21_RS06800	COG3743	rRNA binding
BSK21_RS06820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSK21_RS06825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSK21_RS06830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSK21_RS06835	COG0248	Ppx GppA phosphatase
BSK21_RS06845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSK21_RS06855	COG3842	ATPase activity
BSK21_RS06860	COG0366	Alpha amylase catalytic
BSK21_RS06865	COG0395	ABC-type sugar transport system, permease component
BSK21_RS06870	COG1175	transmembrane transport
BSK21_RS06875	COG1653	transport
BSK21_RS06880	COG1609	Transcriptional regulator
BSK21_RS06885	COG0837	glucose binding
BSK21_RS06905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSK21_RS06915	COG0840	transmembrane signaling receptor activity
BSK21_RS06925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSK21_RS06930	COG0745	RESPONSE REGULATOR receiver
BSK21_RS06940	COG0482	sulfurtransferase activity
BSK21_RS06945	COG1238	metal cluster binding
BSK21_RS06950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSK21_RS06960	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSK21_RS06965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSK21_RS06975	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSK21_RS06980	COG0750	zinc metalloprotease
BSK21_RS06985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSK21_RS06995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSK21_RS07000	COG0233	cytoplasmic translational termination
BSK21_RS07005	COG0528	UMP kinase activity
BSK21_RS07010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSK21_RS07020	COG0739	heme binding
BSK21_RS07020	COG0741	lytic transglycosylase activity
BSK21_RS07020	COG1196	nuclear chromosome segregation
BSK21_RS07040	COG0629	single-stranded DNA binding
BSK21_RS07045	COG2166	iron-sulfur cluster assembly
BSK21_RS07055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSK21_RS07060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSK21_RS07070	COG0842	Transport permease protein
BSK21_RS07075	COG1131	(ABC) transporter
BSK21_RS07090	COG0318	PFAM AMP-dependent synthetase and ligase
BSK21_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS07115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSK21_RS07120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BSK21_RS07120	COG3264	Mechanosensitive ion channel
BSK21_RS07130	COG0494	nUDIX hydrolase
BSK21_RS07140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSK21_RS07145	COG0415	Belongs to the DNA photolyase family
BSK21_RS07150	COG0604	alcohol dehydrogenase
BSK21_RS07165	COG2059	Chromate
BSK21_RS07175	COG0114	fumarate hydratase activity
BSK21_RS07205	COG0785	Cytochrome C biogenesis protein
BSK21_RS07210	COG1530	ribonuclease E activity
BSK21_RS07215	COG2204	response regulator
BSK21_RS07225	COG0047	phosphoribosylformylglycinamidine synthase activity
BSK21_RS07230	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSK21_RS07235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSK21_RS07245	COG0646	methionine synthase
BSK21_RS07245	COG1410	methionine synthase
BSK21_RS07250	COG5012	cobalamin binding
BSK21_RS07260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSK21_RS07265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSK21_RS07275	COG4974	Belongs to the 'phage' integrase family
BSK21_RS07280	COG4536	flavin adenine dinucleotide binding
BSK21_RS07285	COG0433	COG0433 Predicted ATPase
BSK21_RS07305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSK21_RS07310	COG2989	Protein conserved in bacteria
BSK21_RS07335	COG0840	transmembrane signaling receptor activity
BSK21_RS07345	COG1984	allophanate hydrolase subunit 2
BSK21_RS07350	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSK21_RS07355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSK21_RS07360	COG1522	sequence-specific DNA binding
BSK21_RS07365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSK21_RS07370	COG1024	Enoyl-CoA hydratase
BSK21_RS07375	COG0318	PFAM AMP-dependent synthetase and ligase
BSK21_RS07415	COG1278	Cold shock
BSK21_RS07420	COG0259	pyridoxamine-phosphate oxidase activity
BSK21_RS07425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSK21_RS07435	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BSK21_RS07445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSK21_RS07455	COG0698	ribose 5-phosphate isomerase
BSK21_RS07470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSK21_RS07485	COG0303	'Molybdopterin
BSK21_RS07490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSK21_RS07495	COG0658	competence protein
BSK21_RS07495	COG2333	competence protein COMEC
BSK21_RS07500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSK21_RS07505	COG0372	Belongs to the citrate synthase family
BSK21_RS07510	COG1024	Enoyl-CoA hydratase
BSK21_RS07515	COG3088	subunit of a heme lyase
BSK21_RS07520	COG1138	Cytochrome C-type biogenesis protein
BSK21_RS07540	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSK21_RS07545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSK21_RS07550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSK21_RS07560	COG0583	DNA-binding transcription factor activity
BSK21_RS07565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSK21_RS07570	COG1357	PFAM Pentapeptide repeats (8 copies)
BSK21_RS07575	COG0271	Belongs to the BolA IbaG family
BSK21_RS07580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSK21_RS07600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSK21_RS07605	COG2354	Protein conserved in bacteria
BSK21_RS07630	COG0126	phosphoglycerate kinase activity
BSK21_RS07635	COG3588	fructose-bisphosphate aldolase
BSK21_RS07645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSK21_RS07650	COG0022	dehydrogenase e1 component
BSK21_RS07650	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK21_RS07655	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK21_RS07750	COG4695	Portal protein
BSK21_RS07760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSK21_RS07765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSK21_RS07790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSK21_RS07800	COG0360	Binds together with S18 to 16S ribosomal RNA
BSK21_RS07805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSK21_RS07810	COG0359	binds to the 23S rRNA
BSK21_RS07820	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSK21_RS07835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSK21_RS07835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSK21_RS07865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSK21_RS07870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSK21_RS07875	COG1560	Kdo2-lipid A biosynthetic process
BSK21_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK21_RS07905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSK21_RS07910	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSK21_RS07915	COG4133	protoheme IX ABC transporter activity
BSK21_RS07920	COG3737	Protein of unknown function (DUF498/DUF598)
BSK21_RS07925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSK21_RS07930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSK21_RS07935	COG1862	Preprotein translocase
BSK21_RS07945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSK21_RS07955	COG1160	GTP binding
BSK21_RS07960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSK21_RS07975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSK21_RS07980	COG5265	(ABC) transporter
BSK21_RS07990	COG1611	Belongs to the LOG family
BSK21_RS08000	COG0840	transmembrane signaling receptor activity
BSK21_RS08025	COG3119	arylsulfatase activity
BSK21_RS08050	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS08050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSK21_RS08060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK21_RS08065	COG4235	cytochrome complex assembly
BSK21_RS08070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSK21_RS08090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSK21_RS08100	COG3384	dioxygenase
BSK21_RS08110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSK21_RS08135	COG2379	hydroxypyruvate reductase
BSK21_RS08150	COG0587	DNA-directed DNA polymerase activity
BSK21_RS08155	COG0583	DNA-binding transcription factor activity
BSK21_RS08175	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSK21_RS08185	COG0596	Alpha beta hydrolase
BSK21_RS08195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSK21_RS08205	COG1393	Belongs to the ArsC family
BSK21_RS08210	COG1278	Cold shock
BSK21_RS08220	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BSK21_RS08245	COG1846	Transcriptional regulator
BSK21_RS08270	COG0534	Mate efflux family protein
BSK21_RS08290	COG0187	DNA topoisomerase II activity
BSK21_RS08300	COG2010	Cytochrome c
BSK21_RS08310	COG1136	(ABC) transporter
BSK21_RS08315	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSK21_RS08320	COG0442	prolyl-tRNA aminoacylation
BSK21_RS08325	COG0628	permease
BSK21_RS08335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSK21_RS08340	COG0248	Ppx GppA phosphatase
BSK21_RS08350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BSK21_RS08355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSK21_RS08360	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSK21_RS08360	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSK21_RS08375	COG4770	biotin carboxylase activity
BSK21_RS08400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSK21_RS08410	COG3800	Transcriptional regulator
BSK21_RS08410	COG1396	sequence-specific DNA binding
BSK21_RS08435	COG3119	arylsulfatase activity
BSK21_RS08440	COG1309	transcriptional regulator
BSK21_RS08455	COG4175	Glycine betaine
BSK21_RS08470	COG0583	DNA-binding transcription factor activity
BSK21_RS08475	COG0217	transcriptional regulatory protein
BSK21_RS08480	COG3273	potassium ion transport
BSK21_RS08480	COG0471	metal ion transport
BSK21_RS08485	COG1692	metallophosphoesterase
BSK21_RS08490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSK21_RS08495	COG2239	Acts as a magnesium transporter
BSK21_RS08500	COG0402	S-adenosylhomocysteine deaminase activity
BSK21_RS08520	COG0670	Belongs to the BI1 family
BSK21_RS08530	COG0583	DNA-binding transcription factor activity
BSK21_RS08535	COG0604	alcohol dehydrogenase
BSK21_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS08535	COG3321	synthase
BSK21_RS08545	COG0483	inositol monophosphate 1-phosphatase activity
BSK21_RS08555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSK21_RS08565	COG0415	Belongs to the DNA photolyase family
BSK21_RS08570	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSK21_RS08575	COG0154	amidase activity
BSK21_RS08585	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSK21_RS08590	COG0590	tRNA wobble adenosine to inosine editing
BSK21_RS08595	COG1187	pseudouridine synthase activity
BSK21_RS08645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSK21_RS08650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSK21_RS08660	COG0735	belongs to the Fur family
BSK21_RS08665	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BSK21_RS08725	COG0667	Aldo Keto reductase
BSK21_RS08735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK21_RS08740	COG2255	four-way junction helicase activity
BSK21_RS08745	COG0632	four-way junction helicase activity
BSK21_RS08765	COG2264	protein methyltransferase activity
BSK21_RS08775	COG2391	methyltransferase activity
BSK21_RS08785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSK21_RS08795	COG1183	phosphatidylcholine synthase activity
BSK21_RS08800	COG4974	Belongs to the 'phage' integrase family
BSK21_RS08810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSK21_RS08820	COG3768	UPF0283 membrane protein
BSK21_RS08825	COG3106	COG3106 Predicted ATPase
BSK21_RS08830	COG0101	tRNA pseudouridine synthase activity
BSK21_RS08835	COG0729	surface antigen
BSK21_RS08860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK21_RS08875	COG3842	ATPase activity
BSK21_RS08880	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSK21_RS08885	COG1177	transmembrane transport
BSK21_RS08890	COG1618	nucleotide phosphatase activity, acting on free nucleotides
BSK21_RS08890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSK21_RS08895	COG0746	molybdenum cofactor guanylyltransferase activity
BSK21_RS08900	COG0425	Belongs to the sulfur carrier protein TusA family
BSK21_RS08915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSK21_RS08935	COG1522	sequence-specific DNA binding
BSK21_RS08940	COG0492	ferredoxin-NADP+ reductase activity
BSK21_RS08945	COG3038	cytochrome b561
BSK21_RS08955	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK21_RS08965	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSK21_RS08970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSK21_RS08985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSK21_RS08990	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS08995	COG0583	DNA-binding transcription factor activity
BSK21_RS09000	COG4149	molybdate abc transporter
BSK21_RS09005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSK21_RS09020	COG0006	proline dipeptidase activity
BSK21_RS09030	COG1522	sequence-specific DNA binding
BSK21_RS09035	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS09035	COG1902	pentaerythritol trinitrate reductase activity
BSK21_RS09045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK21_RS09055	COG4638	Rieske (2fe-2S)
BSK21_RS09060	COG0583	DNA-binding transcription factor activity
BSK21_RS09065	COG3257	ureidoglycine aminohydrolase activity
BSK21_RS09075	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BSK21_RS09085	COG2351	hydroxyisourate hydrolase activity
BSK21_RS09090	COG0583	DNA-binding transcription factor activity
BSK21_RS09100	COG1858	cytochrome C peroxidase
BSK21_RS09115	COG4213	ABC transporter substrate-binding protein
BSK21_RS09120	COG4214	carbohydrate transport
BSK21_RS09130	COG1070	Carbohydrate kinase
BSK21_RS09135	COG2115	Belongs to the xylose isomerase family
BSK21_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS09160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK21_RS09185	COG4964	Belongs to the GSP D family
BSK21_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
BSK21_RS09260	COG0318	PFAM AMP-dependent synthetase and ligase
BSK21_RS09265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK21_RS09270	COG2197	response regulator
BSK21_RS09275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSK21_RS09290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK21_RS09325	COG0069	glutamate synthase activity
BSK21_RS09335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK21_RS09340	COG0589	response to stress
BSK21_RS09350	COG2358	TRAP transporter, solute receptor (TAXI family
BSK21_RS09355	COG1737	Transcriptional regulator
BSK21_RS09365	COG4948	Mandelate Racemase Muconate Lactonizing
BSK21_RS09375	COG4175	Glycine betaine
BSK21_RS09375	COG0517	IMP dehydrogenase activity
BSK21_RS09380	COG4176	ABC-type proline glycine betaine transport system permease component
BSK21_RS09390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BSK21_RS09410	COG1012	belongs to the aldehyde dehydrogenase family
BSK21_RS09425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSK21_RS09425	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS09430	COG4311	Sarcosine oxidase, delta subunit
BSK21_RS09440	COG4977	sequence-specific DNA binding
BSK21_RS09465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSK21_RS09475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSK21_RS09490	COG1228	amidohydrolase
BSK21_RS09495	COG2986	histidine ammonia-lyase
BSK21_RS09505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSK21_RS09520	COG0601	transmembrane transport
BSK21_RS09525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK21_RS09530	COG4172	Belongs to the ABC transporter superfamily
BSK21_RS09535	COG3608	succinylglutamate desuccinylase aspartoacylase
BSK21_RS09540	COG1017	nitric oxide dioxygenase activity
BSK21_RS09540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSK21_RS09560	COG0277	FAD linked oxidase domain protein
BSK21_RS09595	COG4584	PFAM Integrase catalytic
BSK21_RS09625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSK21_RS09645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSK21_RS09655	COG0084	hydrolase, TatD family'
BSK21_RS09660	COG1234	tRNA 3'-trailer cleavage
BSK21_RS09675	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSK21_RS09685	COG3842	ATPase activity
BSK21_RS09710	COG0321	lipoyl(octanoyl) transferase activity
BSK21_RS09725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK21_RS09730	COG1610	YqeY-like protein
BSK21_RS09735	COG0505	Belongs to the CarA family
BSK21_RS09740	COG1215	transferase activity, transferring glycosyl groups
BSK21_RS09750	COG1802	Transcriptional regulator
BSK21_RS09760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSK21_RS09770	COG1522	sequence-specific DNA binding
BSK21_RS09780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSK21_RS09785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSK21_RS09790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSK21_RS09795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSK21_RS09800	COG3773	Cell wall hydrolase
BSK21_RS09800	COG3409	Peptidoglycan-binding domain 1 protein
BSK21_RS09805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSK21_RS09805	COG0574	Belongs to the PEP-utilizing enzyme family
BSK21_RS09810	COG0751	glycine-tRNA ligase activity
BSK21_RS09820	COG0752	glycyl-tRNA synthetase alpha subunit
BSK21_RS09830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSK21_RS09840	COG1469	GTP cyclohydrolase I activity
BSK21_RS09850	COG0625	glutathione transferase activity
BSK21_RS09860	COG2917	probably involved in intracellular septation
BSK21_RS09870	COG0552	protein localization to endoplasmic reticulum
BSK21_RS09900	COG1570	exodeoxyribonuclease VII activity
BSK21_RS09905	COG1329	Transcriptional regulator
BSK21_RS09910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSK21_RS09915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BSK21_RS09935	COG2267	carboxylic ester hydrolase activity
BSK21_RS09960	COG0564	pseudouridine synthase activity
BSK21_RS09995	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSK21_RS10000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSK21_RS10000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSK21_RS10025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSK21_RS10025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSK21_RS10035	COG0432	Pfam Uncharacterised protein family UPF0047
BSK21_RS10045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSK21_RS10050	COG0358	DNA primase activity
BSK21_RS10070	COG1741	Belongs to the pirin family
BSK21_RS10095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSK21_RS10115	COG2132	Multicopper oxidase
BSK21_RS10150	COG1138	Cytochrome C-type biogenesis protein
BSK21_RS10155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK21_RS10160	COG3088	subunit of a heme lyase
BSK21_RS10165	COG4235	cytochrome complex assembly
BSK21_RS10170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSK21_RS10205	COG2010	Cytochrome c
BSK21_RS10210	COG2132	Multicopper oxidase
BSK21_RS10220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSK21_RS10220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSK21_RS10225	COG1742	UPF0060 membrane protein
BSK21_RS10290	COG0582	viral genome integration into host DNA
BSK21_RS10305	COG4948	Mandelate Racemase Muconate Lactonizing
BSK21_RS10330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK21_RS10335	COG0601	transmembrane transport
BSK21_RS10340	COG0747	negative chemotaxis
BSK21_RS10345	COG0824	Thioesterase
BSK21_RS10345	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK21_RS10350	COG3246	L-lysine catabolic process to acetate
BSK21_RS10365	COG1024	Enoyl-CoA hydratase
BSK21_RS10375	COG1960	acyl-CoA dehydrogenase activity
BSK21_RS10385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSK21_RS10390	COG1940	carbohydrate kinase activity
BSK21_RS10400	COG0019	diaminopimelate decarboxylase activity
BSK21_RS10410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSK21_RS10410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSK21_RS10415	COG0509	glycine decarboxylation via glycine cleavage system
BSK21_RS10420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSK21_RS10430	COG0156	8-amino-7-oxononanoate synthase activity
BSK21_RS10445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSK21_RS10455	COG3258	Cytochrome c
BSK21_RS10480	COG0785	Cytochrome C biogenesis protein
BSK21_RS10495	COG2391	methyltransferase activity
BSK21_RS10505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSK21_RS10550	COG0459	protein refolding
BSK21_RS10555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSK21_RS10570	COG1227	inorganic diphosphatase activity
BSK21_RS10585	COG2030	dehydratase
BSK21_RS10590	COG0196	riboflavin kinase activity
BSK21_RS10595	COG2983	Belongs to the UPF0260 family
BSK21_RS10615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSK21_RS10620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSK21_RS10625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSK21_RS10630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSK21_RS10635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSK21_RS10645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK21_RS10670	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BSK21_RS10680	COG0287	Prephenate dehydrogenase
BSK21_RS10685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSK21_RS10690	COG2169	Transcriptional regulator
BSK21_RS10690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSK21_RS10695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSK21_RS10730	COG3318	Belongs to the UPF0149 family
BSK21_RS10730	COG3012	SEC-C Motif Domain Protein
BSK21_RS10760	COG3842	ATPase activity
BSK21_RS10770	COG0395	ABC-type sugar transport system, permease component
BSK21_RS10775	COG1175	transmembrane transport
BSK21_RS10785	COG1609	Transcriptional regulator
BSK21_RS10815	COG0800	Aldolase
BSK21_RS10820	COG3734	2-keto-3-deoxy-galactonokinase
BSK21_RS10830	COG0395	ABC-type sugar transport system, permease component
BSK21_RS10835	COG1175	transmembrane transport
BSK21_RS10845	COG1414	Transcriptional regulator
BSK21_RS10860	COG4948	Mandelate Racemase Muconate Lactonizing
BSK21_RS10870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSK21_RS10880	COG1349	DNA-binding transcription factor activity
BSK21_RS10900	COG0582	viral genome integration into host DNA
BSK21_RS10910	COG3454	Phosphonate metabolism
BSK21_RS10920	COG4778	phosphonate C-P lyase system protein PhnL
BSK21_RS10925	COG4107	phosphonate C-P lyase system protein PhnK
BSK21_RS10930	COG3627	carbon phosphorus lyase activity
BSK21_RS10935	COG3626	phosphonate metabolism
BSK21_RS10945	COG3624	Phosphonate C-P lyase system protein PhnG
BSK21_RS10950	COG2188	Transcriptional regulator
BSK21_RS10960	COG3639	organic phosphonate transmembrane transporter activity
BSK21_RS10965	COG3639	organic phosphonate transmembrane transporter activity
BSK21_RS10970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BSK21_RS10975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSK21_RS11040	COG0768	penicillin binding
BSK21_RS11045	COG0772	Belongs to the SEDS family
BSK21_RS11050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSK21_RS11060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSK21_RS11085	COG2353	YceI-like domain
BSK21_RS11090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSK21_RS11095	COG1012	belongs to the aldehyde dehydrogenase family
BSK21_RS11100	COG1162	GTPase activity
BSK21_RS11115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSK21_RS11125	COG0124	histidyl-tRNA synthetase
BSK21_RS11130	COG2900	Belongs to the SlyX family
BSK21_RS11160	COG3845	ABC transporter
BSK21_RS11165	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS11170	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS11195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSK21_RS11200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSK21_RS11230	COG0339	signal peptide processing
BSK21_RS11235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSK21_RS11240	COG0756	dUTP diphosphatase activity
BSK21_RS11245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSK21_RS11275	COG0606	chelatase, subunit chli
BSK21_RS11290	COG0792	nuclease activity
BSK21_RS11295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSK21_RS11305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSK21_RS11325	COG0180	Tryptophanyl-tRNA synthetase
BSK21_RS11340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSK21_RS11355	COG1744	ABC transporter substrate-binding protein PnrA-like
BSK21_RS11360	COG3845	ABC transporter
BSK21_RS11365	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS11370	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS11375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSK21_RS11425	COG2030	dehydratase
BSK21_RS11450	COG0039	L-malate dehydrogenase activity
BSK21_RS11455	COG0045	succinate-CoA ligase (ADP-forming) activity
BSK21_RS11460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSK21_RS11470	COG0567	Dehydrogenase, E1 component
BSK21_RS11475	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK21_RS11520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSK21_RS11550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSK21_RS11555	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BSK21_RS11575	COG3551	Protein conserved in bacteria
BSK21_RS11605	COG4181	ATPase activity
BSK21_RS11625	COG2943	transferase activity, transferring hexosyl groups
BSK21_RS11630	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BSK21_RS11645	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSK21_RS11655	COG0424	maF-like protein
BSK21_RS11660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSK21_RS11665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSK21_RS11685	COG5328	Belongs to the UPF0262 family
BSK21_RS11690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSK21_RS11700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSK21_RS11710	COG0840	transmembrane signaling receptor activity
BSK21_RS11720	COG0527	aspartate kinase activity
BSK21_RS11725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSK21_RS11750	COG0659	secondary active sulfate transmembrane transporter activity
BSK21_RS11755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSK21_RS11760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSK21_RS11815	COG4964	Belongs to the GSP D family
BSK21_RS11850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSK21_RS11880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSK21_RS11880	COG1754	DNA topoisomerase type I activity
BSK21_RS11890	COG0758	DNA mediated transformation
BSK21_RS11890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSK21_RS11900	COG0312	modulator of DNA gyrase
BSK21_RS11910	COG0109	protoheme IX farnesyltransferase activity
BSK21_RS11920	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSK21_RS11930	COG3346	SURF1 family
BSK21_RS11940	COG0612	Peptidase, M16
BSK21_RS11945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK21_RS11950	COG0277	FAD linked oxidase domain protein
BSK21_RS11955	COG1643	Atp-dependent helicase
BSK21_RS11960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSK21_RS11970	COG0306	phosphate transporter
BSK21_RS11980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSK21_RS11985	COG0842	Transport permease protein
BSK21_RS12010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSK21_RS12045	COG2326	polyphosphate kinase activity
BSK21_RS12065	COG1872	DUF167
BSK21_RS12085	COG0346	lactoylglutathione lyase activity
BSK21_RS12095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSK21_RS12105	COG0512	Glutamine amidotransferase of anthranilate synthase
BSK21_RS12105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSK21_RS12110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSK21_RS12125	COG1435	thymidine kinase activity
BSK21_RS12130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSK21_RS12135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK21_RS12140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK21_RS12150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSK21_RS12155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSK21_RS12160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSK21_RS12165	COG1253	flavin adenine dinucleotide binding
BSK21_RS12170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSK21_RS12175	COG1702	phosphate starvation-inducible protein PhoH
BSK21_RS12190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSK21_RS12205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSK21_RS12210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSK21_RS12215	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSK21_RS12225	COG1047	Peptidyl-prolyl cis-trans
BSK21_RS12240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSK21_RS12260	COG0488	(ABC) transporter
BSK21_RS12265	COG0667	Aldo Keto reductase
BSK21_RS12270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSK21_RS12285	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BSK21_RS12305	COG0556	nucleotide-excision repair
BSK21_RS12325	COG3842	ATPase activity
BSK21_RS12330	COG0395	ABC-type sugar transport system, permease component
BSK21_RS12340	COG1653	transport
BSK21_RS12345	COG1609	Transcriptional regulator
BSK21_RS12350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSK21_RS12365	COG3842	ATPase activity
BSK21_RS12370	COG0395	ABC-type sugar transport system, permease component
BSK21_RS12375	COG1175	transmembrane transport
BSK21_RS12385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSK21_RS12390	COG4989	oxidoreductase activity
BSK21_RS12400	COG2188	Transcriptional regulator
BSK21_RS12405	COG0673	inositol 2-dehydrogenase activity
BSK21_RS12410	COG0662	Cupin 2, conserved barrel domain protein
BSK21_RS12440	COG0028	Belongs to the TPP enzyme family
BSK21_RS12460	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSK21_RS12460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSK21_RS12465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSK21_RS12475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK21_RS12495	COG4176	ABC-type proline glycine betaine transport system permease component
BSK21_RS12515	COG1802	Transcriptional regulator
BSK21_RS12520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSK21_RS12530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSK21_RS12535	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BSK21_RS12540	COG1228	amidohydrolase
BSK21_RS12575	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSK21_RS12580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSK21_RS12590	COG0542	response to heat
BSK21_RS12595	COG0284	orotidine-5'-phosphate decarboxylase activity
BSK21_RS12620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSK21_RS12635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSK21_RS12640	COG1404	Belongs to the peptidase S8 family
BSK21_RS12650	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BSK21_RS12680	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSK21_RS12725	COG0584	glycerophosphoryl diester phosphodiesterase
BSK21_RS12735	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSK21_RS12740	COG0668	transmembrane transport
BSK21_RS12745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSK21_RS12745	COG0678	peroxiredoxin activity
BSK21_RS12755	COG0742	ribosomal rna small subunit methyltransferase
BSK21_RS12770	COG0024	Methionine aminopeptidase
BSK21_RS12775	COG1489	DNA binding
BSK21_RS12780	COG1546	Belongs to the CinA family
BSK21_RS12780	COG1058	Belongs to the CinA family
BSK21_RS12810	COG0583	DNA-binding transcription factor activity
BSK21_RS12815	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSK21_RS12815	COG1902	pentaerythritol trinitrate reductase activity
BSK21_RS12835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSK21_RS12850	COG1652	LysM domain
BSK21_RS12855	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSK21_RS12865	COG2423	ornithine cyclodeaminase activity
BSK21_RS12875	COG1671	Belongs to the UPF0178 family
BSK21_RS12880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSK21_RS12885	COG0679	Auxin Efflux Carrier
BSK21_RS12890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSK21_RS12895	COG0799	negative regulation of ribosome biogenesis
BSK21_RS12900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSK21_RS12905	COG0066	3-isopropylmalate dehydratase activity
BSK21_RS12920	COG0473	3-isopropylmalate dehydrogenase activity
BSK21_RS12925	COG0697	spore germination
BSK21_RS12950	COG0348	domain, Protein
BSK21_RS12955	COG2010	Cytochrome c
BSK21_RS12980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSK21_RS12985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSK21_RS13000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSK21_RS13005	COG0288	reversible hydration of carbon dioxide
BSK21_RS13015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSK21_RS13035	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSK21_RS13055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSK21_RS13065	COG0793	Belongs to the peptidase S41A family
BSK21_RS13070	COG1051	belongs to the nudix hydrolase family
BSK21_RS13075	COG2951	lytic endotransglycosylase activity
BSK21_RS13080	COG0557	exoribonuclease II activity
BSK21_RS13085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK21_RS13105	COG2171	N-acyltransferase activity
BSK21_RS13115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSK21_RS13130	COG0560	Phosphoserine phosphatase
BSK21_RS13130	COG3830	Belongs to the UPF0237 family
BSK21_RS13140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSK21_RS13145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSK21_RS13150	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BSK21_RS13160	COG0183	Belongs to the thiolase family
BSK21_RS13165	COG3022	response to hydroperoxide
BSK21_RS13170	COG0514	ATP-dependent DNA helicase (RecQ)
BSK21_RS13175	COG2835	tetraacyldisaccharide 4'-kinase activity
BSK21_RS13195	COG0745	RESPONSE REGULATOR receiver
BSK21_RS13210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSK21_RS13240	COG0582	viral genome integration into host DNA
BSK21_RS13255	COG0495	leucyl-tRNA aminoacylation
BSK21_RS13280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSK21_RS13290	COG1024	Enoyl-CoA hydratase
BSK21_RS13295	COG0300	oxidoreductase activity
BSK21_RS13305	COG0312	modulator of DNA gyrase
BSK21_RS13315	COG1215	transferase activity, transferring glycosyl groups
BSK21_RS13330	COG1519	Transferase
BSK21_RS13340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSK21_RS13350	COG1194	a g-specific adenine glycosylase
BSK21_RS13365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSK21_RS13435	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BSK21_RS13440	COG0732	type I restriction modification DNA specificity domain
BSK21_RS13455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSK21_RS13520	COG1609	Transcriptional regulator
BSK21_RS13525	COG2308	Evidence 4 Homologs of previously reported genes of
BSK21_RS13560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSK21_RS13565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSK21_RS13575	COG0625	glutathione transferase activity
BSK21_RS13600	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BSK21_RS13610	COG4143	(ABC) transporter
BSK21_RS13615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSK21_RS13630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSK21_RS13645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSK21_RS13650	COG0142	geranyltranstransferase activity
BSK21_RS13655	COG1722	exodeoxyribonuclease VII activity
BSK21_RS13660	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSK21_RS13665	COG0745	RESPONSE REGULATOR receiver
BSK21_RS13670	COG1846	Transcriptional regulator
BSK21_RS13675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSK21_RS13690	COG0765	amino acid transport
BSK21_RS13695	COG0348	domain, Protein
BSK21_RS13695	COG3901	Regulator of nitric oxide reductase transcription
BSK21_RS13745	COG1131	(ABC) transporter
BSK21_RS13760	COG1116	anion transmembrane transporter activity
BSK21_RS13765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSK21_RS13785	COG5002	protein histidine kinase activity
BSK21_RS13785	COG0784	Response regulator, receiver
BSK21_RS13785	COG2198	Histidine kinase
BSK21_RS13795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSK21_RS13805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSK21_RS13830	COG1968	undecaprenyl-diphosphatase activity
BSK21_RS13845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK21_RS13865	COG1137	ATPase activity
BSK21_RS13870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSK21_RS13875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK21_RS13915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSK21_RS13935	COG0443	Heat shock 70 kDa protein
BSK21_RS13945	COG2003	Belongs to the UPF0758 family
BSK21_RS13960	COG0653	protein targeting
BSK21_RS13965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSK21_RS13970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSK21_RS13975	COG0494	nUDIX hydrolase
BSK21_RS13980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSK21_RS13995	COG0779	Required for maturation of 30S ribosomal subunits
BSK21_RS14010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSK21_RS14020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSK21_RS14025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSK21_RS14030	COG1040	competence protein
BSK21_RS14060	COG3034	peptidoglycan biosynthetic process
BSK21_RS14065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSK21_RS14075	COG0494	nUDIX hydrolase
BSK21_RS14085	COG0494	nUDIX hydrolase
BSK21_RS14095	COG0137	argininosuccinate synthase activity
BSK21_RS14115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK21_RS14120	COG0280	phosphate acetyltransferase
BSK21_RS14120	COG0281	malic enzyme
BSK21_RS14125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSK21_RS14130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSK21_RS14135	COG1420	regulation of RNA biosynthetic process
BSK21_RS14140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSK21_RS14145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSK21_RS14150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSK21_RS14165	COG0357	Ribosomal RNA small subunit methyltransferase G
BSK21_RS14170	COG0445	tRNA wobble uridine modification
BSK21_RS14175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSK21_RS14180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSK21_RS14185	COG1981	membrane
BSK21_RS14190	COG0424	maF-like protein
BSK21_RS14195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSK21_RS14200	COG0237	dephospho-CoA kinase activity
BSK21_RS14205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSK21_RS14210	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSK21_RS14235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSK21_RS14245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSK21_RS14255	COG1074	ATP-dependent DNA helicase activity
BSK21_RS14260	COG2887	Belongs to the helicase family. UvrD subfamily
BSK21_RS14265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSK21_RS14270	COG3178	'Phosphotransferase
BSK21_RS14275	COG0802	atpase or kinase
BSK21_RS14280	COG2205	protein histidine kinase activity
BSK21_RS14290	COG1999	signal sequence binding
BSK21_RS14295	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSK21_RS14300	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BSK21_RS14305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSK21_RS14325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSK21_RS14330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSK21_RS14390	COG0789	Transcriptional regulator
BSK21_RS14395	COG1999	signal sequence binding
BSK21_RS14405	COG1999	signal sequence binding
BSK21_RS14480	COG1309	transcriptional regulator
BSK21_RS14500	COG1959	2 iron, 2 sulfur cluster binding
BSK21_RS14515	COG0174	glutamine synthetase
BSK21_RS14570	COG4134	Bacterial extracellular solute-binding protein
BSK21_RS14575	COG4135	transport system, permease component
BSK21_RS14580	COG4136	ATPase activity
BSK21_RS14585	COG1309	transcriptional regulator
BSK21_RS14615	COG1360	Flagellar Motor Protein
BSK21_RS14635	COG1706	bacterial-type flagellum-dependent cell motility
BSK21_RS14640	COG1338	Plays a role in the flagellum-specific transport system
BSK21_RS14645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSK21_RS14655	COG1766	The M ring may be actively involved in energy transduction
BSK21_RS14675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSK21_RS14685	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSK21_RS14690	COG1684	flagellar biosynthetic protein fliR
BSK21_RS14710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BSK21_RS14720	COG4786	Flagellar basal body rod
BSK21_RS14725	COG4786	Flagellar basal body rod
BSK21_RS14730	COG1987	bacterial-type flagellum assembly
BSK21_RS14735	COG1677	Flagellar hook-basal body complex protein FliE
BSK21_RS14740	COG1558	bacterial-type flagellum-dependent cell motility
BSK21_RS14745	COG1815	bacterial-type flagellum-dependent cell motility
BSK21_RS14750	COG1157	protein secretion by the type III secretion system
BSK21_RS14760	COG5443	negative regulation of bacterial-type flagellum assembly
BSK21_RS14800	COG2226	methyltransferase
BSK21_RS14805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSK21_RS14815	COG0268	Binds directly to 16S ribosomal RNA
BSK21_RS14830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSK21_RS14840	COG1280	lysine exporter protein (LysE YggA)
BSK21_RS14850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSK21_RS14855	COG1346	cytolysis
BSK21_RS14870	COG1054	Belongs to the UPF0176 family
BSK21_RS14875	COG1335	isochorismatase
BSK21_RS14880	COG0659	secondary active sulfate transmembrane transporter activity
BSK21_RS14905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSK21_RS14915	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BSK21_RS14920	COG2270	Major facilitator Superfamily
BSK21_RS14935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSK21_RS14940	COG0154	amidase activity
BSK21_RS14945	COG0436	Aminotransferase
BSK21_RS14950	COG1674	ftsk spoiiie
BSK21_RS15650	COG3246	L-lysine catabolic process to acetate
BSK21_RS15735	COG0133	tryptophan synthase activity