locus-tag	class	description
DN752_RS00040	COG0831	urea catabolic process
DN752_RS00045	COG0832	Belongs to the urease beta subunit family
DN752_RS00050	COG0804	urea catabolic process
DN752_RS00055	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DN752_RS00060	COG0830	nickel cation binding
DN752_RS00065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DN752_RS00070	COG0829	nickel cation binding
DN752_RS00080	COG4413	Urea transporter
DN752_RS00100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN752_RS00115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN752_RS00140	COG4771	TonB-dependent receptor
DN752_RS00145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN752_RS00150	COG3940	Belongs to the glycosyl hydrolase 43 family
DN752_RS00155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN752_RS00175	COG0352	thiamine-phosphate diphosphorylase activity
DN752_RS00180	COG2022	thiamine diphosphate biosynthetic process
DN752_RS00185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DN752_RS00195	COG0656	L-ascorbic acid biosynthetic process
DN752_RS00200	COG1764	response to oxidative stress
DN752_RS00210	COG0745	RESPONSE REGULATOR receiver
DN752_RS00215	COG5002	protein histidine kinase activity
DN752_RS00230	COG0471	metal ion transport
DN752_RS00250	COG2171	N-acyltransferase activity
DN752_RS00265	COG0803	Belongs to the bacterial solute-binding protein 9 family
DN752_RS00270	COG1121	(ABC) transporter
DN752_RS00275	COG1321	iron dependent repressor
DN752_RS00275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN752_RS00280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN752_RS00290	COG0693	protein deglycase activity
DN752_RS00295	COG0628	permease
DN752_RS00300	COG0004	ammonium transporteR
DN752_RS00350	COG1678	Uncharacterized ACR, COG1678
DN752_RS00355	COG0259	pyridoxamine-phosphate oxidase activity
DN752_RS00360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN752_RS00365	COG0739	heme binding
DN752_RS00370	COG0492	ferredoxin-NADP+ reductase activity
DN752_RS00375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN752_RS00385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DN752_RS00405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DN752_RS00410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DN752_RS00415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DN752_RS00420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN752_RS00440	COG3047	cAMP biosynthetic process
DN752_RS00480	COG3119	arylsulfatase activity
DN752_RS00485	COG5002	protein histidine kinase activity
DN752_RS00485	COG2198	Histidine kinase
DN752_RS00485	COG0784	Response regulator, receiver
DN752_RS00500	COG4774	siderophore transport
DN752_RS00515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DN752_RS00515	COG0116	Belongs to the methyltransferase superfamily
DN752_RS00525	COG0482	sulfurtransferase activity
DN752_RS00535	COG1643	Atp-dependent helicase
DN752_RS00595	COG1629	transport
DN752_RS00595	COG4206	TonB-dependent receptor
DN752_RS00600	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS00610	COG1609	Transcriptional regulator
DN752_RS00660	COG1629	transport
DN752_RS00695	COG1629	transport
DN752_RS00745	COG4771	TonB-dependent receptor
DN752_RS00765	COG2207	Transcriptional regulator
DN752_RS00765	COG1609	Transcriptional regulator
DN752_RS00785	COG3279	Response regulator of the LytR AlgR family
DN752_RS00790	COG3275	phosphorelay sensor kinase activity
DN752_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS00820	COG2271	Major facilitator Superfamily
DN752_RS00845	COG0702	epimerase
DN752_RS00850	COG4771	TonB-dependent receptor
DN752_RS00865	COG3119	arylsulfatase activity
DN752_RS00870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS00875	COG0702	epimerase
DN752_RS00880	COG4771	TonB-dependent receptor
DN752_RS00885	COG2205	protein histidine kinase activity
DN752_RS00885	COG3292	Two component regulator propeller
DN752_RS00885	COG0745	RESPONSE REGULATOR receiver
DN752_RS00890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DN752_RS00895	COG0285	dihydrofolate synthase activity
DN752_RS00905	COG0848	biopolymer transport protein
DN752_RS00910	COG0811	peptide transport
DN752_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN752_RS00955	COG2094	Belongs to the DNA glycosylase MPG family
DN752_RS01025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN752_RS01025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN752_RS01030	COG0358	DNA primase activity
DN752_RS01035	COG0489	protein tyrosine kinase activity
DN752_RS01040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DN752_RS01040	COG0316	Belongs to the HesB IscA family
DN752_RS01050	COG5433	transposase activity
DN752_RS01065	COG4771	TonB-dependent receptor
DN752_RS01065	COG4771	TonB-dependent receptor
DN752_RS01090	COG1069	ribulokinase activity
DN752_RS01095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS01100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN752_RS01105	COG0823	Involved in the tonB-independent uptake of proteins
DN752_RS01115	COG3119	arylsulfatase activity
DN752_RS01125	COG3119	arylsulfatase activity
DN752_RS01130	COG0702	epimerase
DN752_RS01135	COG4771	TonB-dependent receptor
DN752_RS01160	COG0702	epimerase
DN752_RS01165	COG1629	transport
DN752_RS01165	COG4206	TonB-dependent receptor
DN752_RS01185	COG2318	DinB family
DN752_RS01195	COG1017	nitric oxide dioxygenase activity
DN752_RS01195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN752_RS01200	COG2267	carboxylic ester hydrolase activity
DN752_RS01205	COG1335	isochorismatase
DN752_RS01245	COG3940	Belongs to the glycosyl hydrolase 43 family
DN752_RS01250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS01255	COG3119	arylsulfatase activity
DN752_RS01255	COG3408	Glycogen debranching enzyme
DN752_RS01265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DN752_RS01275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS01285	COG0363	glucosamine-6-phosphate deaminase activity
DN752_RS01295	COG0702	epimerase
DN752_RS01300	COG4771	TonB-dependent receptor
DN752_RS01305	COG1609	Transcriptional regulator
DN752_RS01460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN752_RS01470	COG0673	inositol 2-dehydrogenase activity
DN752_RS01485	COG2261	transglycosylase associated protein
DN752_RS01515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DN752_RS01520	COG1309	transcriptional regulator
DN752_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS01540	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN752_RS01545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN752_RS01550	COG0825	malonyl-CoA metabolic process
DN752_RS01570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN752_RS01580	COG2814	Major facilitator Superfamily
DN752_RS01585	COG0488	(ABC) transporter
DN752_RS01590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DN752_RS01595	COG2116	formate transmembrane transporter activity
DN752_RS01630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DN752_RS01635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DN752_RS01640	COG0298	carbon dioxide binding
DN752_RS01645	COG0409	Hydrogenase expression formation protein
DN752_RS01695	COG0123	including yeast histone deacetylase and acetoin utilization protein
DN752_RS01705	COG1950	PFAM Membrane protein of
DN752_RS01735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN752_RS01740	COG0460	homoserine dehydrogenase
DN752_RS01750	COG1115	amino acid carrier protein
DN752_RS01755	COG2177	Part of the ABC transporter FtsEX involved in
DN752_RS01765	COG1968	undecaprenyl-diphosphatase activity
DN752_RS01770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DN752_RS01775	COG0196	riboflavin kinase activity
DN752_RS01780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN752_RS01800	COG3119	arylsulfatase activity
DN752_RS01805	COG3119	arylsulfatase activity
DN752_RS01815	COG0702	epimerase
DN752_RS01875	COG0183	Belongs to the thiolase family
DN752_RS01885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DN752_RS01890	COG1366	Belongs to the anti-sigma-factor antagonist family
DN752_RS01895	COG1234	tRNA 3'-trailer cleavage
DN752_RS01900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DN752_RS01925	COG4977	sequence-specific DNA binding
DN752_RS01925	COG1917	Cupin 2, conserved barrel domain protein
DN752_RS01940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN752_RS01950	COG0408	coproporphyrinogen oxidase activity
DN752_RS01955	COG0671	phosphoesterase, PA-phosphatase related
DN752_RS01960	COG0307	riboflavin synthase, alpha
DN752_RS01965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DN752_RS01970	COG1607	acyl-coa hydrolase
DN752_RS01980	COG2814	Major facilitator Superfamily
DN752_RS01990	COG0783	Belongs to the Dps family
DN752_RS02000	COG2706	6-phosphogluconolactonase activity
DN752_RS02005	COG1278	Cold shock
DN752_RS02010	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS02020	COG3279	Response regulator of the LytR AlgR family
DN752_RS02060	COG0667	Aldo Keto reductase
DN752_RS02065	COG3291	Pkd domain containing protein
DN752_RS02085	COG0561	phosphatase activity
DN752_RS02090	COG4771	TonB-dependent receptor
DN752_RS02115	COG0745	RESPONSE REGULATOR receiver
DN752_RS02115	COG2205	protein histidine kinase activity
DN752_RS02115	COG3292	Two component regulator propeller
DN752_RS02120	COG4771	TonB-dependent receptor
DN752_RS02140	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DN752_RS02145	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DN752_RS02155	COG1131	(ABC) transporter
DN752_RS02165	COG1725	Transcriptional regulator
DN752_RS02175	COG3386	PFAM SMP-30 Gluconolaconase
DN752_RS02180	COG2610	gluconate transmembrane transporter activity
DN752_RS02190	COG0800	Aldolase
DN752_RS02195	COG2186	Transcriptional regulator
DN752_RS02200	COG3250	beta-galactosidase activity
DN752_RS02210	COG3119	arylsulfatase activity
DN752_RS02220	COG3119	arylsulfatase activity
DN752_RS02225	COG0702	epimerase
DN752_RS02230	COG1629	transport
DN752_RS02230	COG4206	TonB-dependent receptor
DN752_RS02260	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN752_RS02285	COG0297	glycogen (starch) synthase activity
DN752_RS02300	COG0438	transferase activity, transferring glycosyl groups
DN752_RS02310	COG2327	Polysaccharide pyruvyl transferase
DN752_RS02320	COG0662	Cupin 2, conserved barrel domain protein
DN752_RS02320	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DN752_RS02325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN752_RS02330	COG0489	protein tyrosine kinase activity
DN752_RS02375	COG2201	protein-glutamate methylesterase activity
DN752_RS02405	COG3119	arylsulfatase activity
DN752_RS02430	COG2354	Protein conserved in bacteria
DN752_RS02440	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN752_RS02440	COG0022	dehydrogenase e1 component
DN752_RS02445	COG4206	TonB-dependent receptor
DN752_RS02445	COG1629	transport
DN752_RS02450	COG0702	epimerase
DN752_RS02460	COG3292	Two component regulator propeller
DN752_RS02460	COG2205	protein histidine kinase activity
DN752_RS02460	COG0745	RESPONSE REGULATOR receiver
DN752_RS02480	COG0561	phosphatase activity
DN752_RS02485	COG4771	TonB-dependent receptor
DN752_RS02495	COG3275	phosphorelay sensor kinase activity
DN752_RS02500	COG3279	Response regulator of the LytR AlgR family
DN752_RS02505	COG0590	tRNA wobble adenosine to inosine editing
DN752_RS02520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN752_RS02525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN752_RS02545	COG1196	nuclear chromosome segregation
DN752_RS02565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN752_RS02580	COG0137	argininosuccinate synthase activity
DN752_RS02585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DN752_RS02600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DN752_RS02610	COG0165	Argininosuccinate lyase
DN752_RS02620	COG0758	DNA mediated transformation
DN752_RS02630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN752_RS02675	COG0277	FAD linked oxidase domain protein
DN752_RS02675	COG0247	lactate metabolic process
DN752_RS02690	COG3250	beta-galactosidase activity
DN752_RS02715	COG2207	Transcriptional regulator
DN752_RS02715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN752_RS02730	COG4771	TonB-dependent receptor
DN752_RS02765	COG1484	DNA-dependent DNA replication
DN752_RS02770	COG4584	PFAM Integrase catalytic
DN752_RS02865	COG0629	single-stranded DNA binding
DN752_RS02875	COG0659	secondary active sulfate transmembrane transporter activity
DN752_RS02885	COG0667	Aldo Keto reductase
DN752_RS02890	COG0667	Aldo Keto reductase
DN752_RS02900	COG2205	protein histidine kinase activity
DN752_RS02900	COG0784	Response regulator, receiver
DN752_RS02900	COG5002	protein histidine kinase activity
DN752_RS02910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DN752_RS02925	COG2135	peptidase activity
DN752_RS02930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN752_RS02945	COG1940	carbohydrate kinase activity
DN752_RS02950	COG0363	glucosamine-6-phosphate deaminase activity
DN752_RS02985	COG1484	DNA-dependent DNA replication
DN752_RS02990	COG4584	PFAM Integrase catalytic
DN752_RS03000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS03025	COG3537	Alpha-1,2-mannosidase
DN752_RS03040	COG3537	Alpha-1,2-mannosidase
DN752_RS03045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN752_RS03065	COG4771	TonB-dependent receptor
DN752_RS03085	COG0702	epimerase
DN752_RS03090	COG1629	transport
DN752_RS03110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN752_RS03115	COG3119	arylsulfatase activity
DN752_RS03120	COG0702	epimerase
DN752_RS03125	COG4771	TonB-dependent receptor
DN752_RS03135	COG1595	DNA-templated transcription, initiation
DN752_RS03155	COG0702	epimerase
DN752_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS03195	COG3119	arylsulfatase activity
DN752_RS03200	COG3119	arylsulfatase activity
DN752_RS03215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN752_RS03235	COG3275	phosphorelay sensor kinase activity
DN752_RS03240	COG3279	Response regulator of the LytR AlgR family
DN752_RS03270	COG0405	Gamma-glutamyltransferase
DN752_RS03290	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DN752_RS03305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN752_RS03310	COG3938	Belongs to the proline racemase family
DN752_RS03325	COG1570	exodeoxyribonuclease VII activity
DN752_RS03330	COG1722	exodeoxyribonuclease VII activity
DN752_RS03345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DN752_RS03355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN752_RS03365	COG0156	8-amino-7-oxononanoate synthase activity
DN752_RS03370	COG0439	Biotin carboxylase
DN752_RS03380	COG0424	maF-like protein
DN752_RS03480	COG2183	response to ionizing radiation
DN752_RS03485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS03495	COG3250	beta-galactosidase activity
DN752_RS03505	COG3537	Alpha-1,2-mannosidase
DN752_RS03525	COG0702	epimerase
DN752_RS03530	COG1629	transport
DN752_RS03540	COG2308	Evidence 4 Homologs of previously reported genes of
DN752_RS03575	COG4771	TonB-dependent receptor
DN752_RS03580	COG0702	epimerase
DN752_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS03635	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DN752_RS03640	COG4677	pectinesterase activity
DN752_RS03670	COG0038	chloride channel
DN752_RS03690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN752_RS03710	COG1858	cytochrome C peroxidase
DN752_RS03730	COG4771	TonB-dependent receptor
DN752_RS03755	COG4771	TonB-dependent receptor
DN752_RS03765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN752_RS03765	COG0604	alcohol dehydrogenase
DN752_RS03765	COG4221	oxidoreductase activity
DN752_RS03765	COG3321	synthase
DN752_RS03770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DN752_RS03785	COG1929	Belongs to the glycerate kinase type-1 family
DN752_RS03795	COG1115	amino acid carrier protein
DN752_RS03805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DN752_RS03815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN752_RS03820	COG0166	Belongs to the GPI family
DN752_RS03885	COG1501	Belongs to the glycosyl hydrolase 31 family
DN752_RS03890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN752_RS03905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN752_RS03910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DN752_RS03945	COG0517	IMP dehydrogenase activity
DN752_RS03960	COG1446	asparaginase
DN752_RS03980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DN752_RS03985	COG0124	histidyl-tRNA synthetase
DN752_RS04000	COG1217	gtp-binding protein TYPA
DN752_RS04010	COG0473	3-isopropylmalate dehydrogenase activity
DN752_RS04015	COG1024	Enoyl-CoA hydratase
DN752_RS04050	COG0756	dUTP diphosphatase activity
DN752_RS04070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DN752_RS04075	COG0154	amidase activity
DN752_RS04080	COG0791	NLP P60 protein
DN752_RS04080	COG1388	LysM domain
DN752_RS04080	COG3103	Sh3 type 3 domain protein
DN752_RS04095	COG0632	four-way junction helicase activity
DN752_RS04105	COG0509	glycine decarboxylation via glycine cleavage system
DN752_RS04140	COG2003	Belongs to the UPF0758 family
DN752_RS04150	COG1595	DNA-templated transcription, initiation
DN752_RS04220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS04335	COG1629	transport
DN752_RS04355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DN752_RS04385	COG0587	DNA-directed DNA polymerase activity
DN752_RS04430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN752_RS04440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN752_RS04505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DN752_RS04515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN752_RS04545	COG1285	pathogenesis
DN752_RS04550	COG3781	membrane
DN752_RS04560	COG2217	Heavy metal translocating P-type atpase
DN752_RS04615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN752_RS04620	COG2217	Heavy metal translocating P-type atpase
DN752_RS04640	COG3344	reverse transcriptase
DN752_RS04685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN752_RS04770	COG2205	protein histidine kinase activity
DN752_RS04785	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DN752_RS04805	COG3119	arylsulfatase activity
DN752_RS04815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS04825	COG0702	epimerase
DN752_RS04830	COG4771	TonB-dependent receptor
DN752_RS04860	COG3119	arylsulfatase activity
DN752_RS04865	COG0702	epimerase
DN752_RS04870	COG4771	TonB-dependent receptor
DN752_RS04875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS04880	COG3292	Two component regulator propeller
DN752_RS04880	COG2205	protein histidine kinase activity
DN752_RS04880	COG0745	RESPONSE REGULATOR receiver
DN752_RS04905	COG1629	transport
DN752_RS04910	COG0702	epimerase
DN752_RS04940	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS04945	COG1012	belongs to the aldehyde dehydrogenase family
DN752_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS04955	COG1063	alcohol dehydrogenase
DN752_RS04990	COG3119	arylsulfatase activity
DN752_RS05005	COG4771	TonB-dependent receptor
DN752_RS05015	COG3119	arylsulfatase activity
DN752_RS05020	COG1063	alcohol dehydrogenase
DN752_RS05025	COG3119	arylsulfatase activity
DN752_RS05030	COG3119	arylsulfatase activity
DN752_RS05035	COG0673	inositol 2-dehydrogenase activity
DN752_RS05040	COG3386	PFAM SMP-30 Gluconolaconase
DN752_RS05045	COG3119	arylsulfatase activity
DN752_RS05070	COG0561	phosphatase activity
DN752_RS05075	COG4771	TonB-dependent receptor
DN752_RS05080	COG0702	epimerase
DN752_RS05085	COG1629	transport
DN752_RS05095	COG3250	beta-galactosidase activity
DN752_RS05100	COG3119	arylsulfatase activity
DN752_RS05100	COG3408	Glycogen debranching enzyme
DN752_RS05110	COG3119	arylsulfatase activity
DN752_RS05115	COG3119	arylsulfatase activity
DN752_RS05135	COG4221	oxidoreductase activity
DN752_RS05165	COG4584	PFAM Integrase catalytic
DN752_RS05170	COG1484	DNA-dependent DNA replication
DN752_RS05180	COG3311	Transcriptional regulator
DN752_RS05210	COG3292	Two component regulator propeller
DN752_RS05210	COG2205	protein histidine kinase activity
DN752_RS05210	COG0745	RESPONSE REGULATOR receiver
DN752_RS05220	COG1331	Highly conserved protein containing a thioredoxin domain
DN752_RS05235	COG4771	TonB-dependent receptor
DN752_RS05245	COG3250	beta-galactosidase activity
DN752_RS05250	COG3250	beta-galactosidase activity
DN752_RS05255	COG3119	arylsulfatase activity
DN752_RS05260	COG3250	beta-galactosidase activity
DN752_RS05285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DN752_RS05315	COG3119	arylsulfatase activity
DN752_RS05320	COG3408	Glycogen debranching enzyme
DN752_RS05320	COG3119	arylsulfatase activity
DN752_RS05335	COG1917	Cupin 2, conserved barrel domain protein
DN752_RS05335	COG4977	sequence-specific DNA binding
DN752_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS05355	COG1063	alcohol dehydrogenase
DN752_RS05380	COG3119	arylsulfatase activity
DN752_RS05390	COG3250	beta-galactosidase activity
DN752_RS05415	COG3119	arylsulfatase activity
DN752_RS05425	COG4771	TonB-dependent receptor
DN752_RS05440	COG1609	Transcriptional regulator
DN752_RS05445	COG1733	regulation of RNA biosynthetic process
DN752_RS05450	COG0604	alcohol dehydrogenase
DN752_RS05475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN752_RS05495	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS05500	COG2271	Major facilitator Superfamily
DN752_RS05550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DN752_RS05590	COG0561	phosphatase activity
DN752_RS05595	COG4771	TonB-dependent receptor
DN752_RS05610	COG0463	Glycosyl transferase, family 2
DN752_RS05610	COG1216	Glycosyl transferase, family 2
DN752_RS05650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DN752_RS05655	COG1218	3'(2'),5'-bisphosphate nucleotidase
DN752_RS05660	COG0662	Cupin 2, conserved barrel domain protein
DN752_RS05660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DN752_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS05685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DN752_RS05795	COG3279	Response regulator of the LytR AlgR family
DN752_RS05840	COG1104	cysteine desulfurase activity
DN752_RS05845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DN752_RS05860	COG4771	TonB-dependent receptor
DN752_RS05890	COG1595	DNA-templated transcription, initiation
DN752_RS05935	COG4771	TonB-dependent receptor
DN752_RS05950	COG4771	TonB-dependent receptor
DN752_RS05965	COG0702	epimerase
DN752_RS05970	COG4771	TonB-dependent receptor
DN752_RS06000	COG2204	response regulator
DN752_RS06005	COG5002	protein histidine kinase activity
DN752_RS06005	COG2205	protein histidine kinase activity
DN752_RS06005	COG0784	Response regulator, receiver
DN752_RS06065	COG0436	Aminotransferase
DN752_RS06095	COG0714	Associated with various cellular activities
DN752_RS06100	COG3119	arylsulfatase activity
DN752_RS06120	COG0006	proline dipeptidase activity
DN752_RS06135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN752_RS06140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DN752_RS06145	COG0193	aminoacyl-tRNA hydrolase activity
DN752_RS06165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN752_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN752_RS06220	COG1136	(ABC) transporter
DN752_RS06220	COG0577	efflux transmembrane transporter activity
DN752_RS06235	COG0463	Glycosyl transferase, family 2
DN752_RS06235	COG1216	Glycosyl transferase, family 2
DN752_RS06240	COG0463	Glycosyl transferase, family 2
DN752_RS06255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DN752_RS06275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DN752_RS06280	COG1366	Belongs to the anti-sigma-factor antagonist family
DN752_RS06290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN752_RS06300	COG0544	peptidyl-prolyl cis-trans isomerase activity
DN752_RS06305	COG0740	serine-type endopeptidase activity
DN752_RS06310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DN752_RS06315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN752_RS06330	COG4771	TonB-dependent receptor
DN752_RS06335	COG1360	Flagellar Motor Protein
DN752_RS06340	COG0602	queuosine metabolic process
DN752_RS06345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DN752_RS06355	COG0481	GTPase activity
DN752_RS06365	COG1629	transport
DN752_RS06385	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
DN752_RS06405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DN752_RS06415	COG2204	response regulator
DN752_RS06420	COG0784	Response regulator, receiver
DN752_RS06420	COG5002	protein histidine kinase activity
DN752_RS06420	COG2198	Histidine kinase
DN752_RS06440	COG0540	Belongs to the ATCase OTCase family
DN752_RS06445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DN752_RS06455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN752_RS06455	COG1796	DNA polymerase
DN752_RS06465	COG1278	Cold shock
DN752_RS06480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DN752_RS06485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DN752_RS06495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DN752_RS06500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN752_RS06525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN752_RS06530	COG1120	ATPase activity
DN752_RS06535	COG1846	Transcriptional regulator
DN752_RS06540	COG0492	ferredoxin-NADP+ reductase activity
DN752_RS06545	COG0633	Ferredoxin
DN752_RS06565	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DN752_RS06565	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DN752_RS06575	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DN752_RS06595	COG1981	membrane
DN752_RS06600	COG1999	signal sequence binding
DN752_RS06615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN752_RS06630	COG1136	(ABC) transporter
DN752_RS06635	COG5002	protein histidine kinase activity
DN752_RS06645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DN752_RS06670	COG1418	mRNA catabolic process
DN752_RS06695	COG2003	Belongs to the UPF0758 family
DN752_RS06700	COG0268	Binds directly to 16S ribosomal RNA
DN752_RS06710	COG0436	Aminotransferase
DN752_RS06715	COG0488	(ABC) transporter
DN752_RS06730	COG3279	Response regulator of the LytR AlgR family
DN752_RS06735	COG3275	phosphorelay sensor kinase activity
DN752_RS06745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DN752_RS06750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DN752_RS06755	COG1136	(ABC) transporter
DN752_RS06755	COG0577	efflux transmembrane transporter activity
DN752_RS06770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DN752_RS06780	COG0745	RESPONSE REGULATOR receiver
DN752_RS06790	COG0564	pseudouridine synthase activity
DN752_RS06800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DN752_RS06805	COG0052	Belongs to the universal ribosomal protein uS2 family
DN752_RS06810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DN752_RS06815	COG0006	proline dipeptidase activity
DN752_RS06820	COG1215	transferase activity, transferring glycosyl groups
DN752_RS06825	COG0612	Peptidase, M16
DN752_RS06850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN752_RS06860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN752_RS06865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN752_RS06870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN752_RS06900	COG1024	Enoyl-CoA hydratase
DN752_RS06915	COG0017	Asparaginyl-tRNA synthetase
DN752_RS06920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DN752_RS06920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DN752_RS06925	COG2270	Major facilitator Superfamily
DN752_RS06945	COG0811	peptide transport
DN752_RS06955	COG0252	asparaginase activity
DN752_RS06960	COG0084	hydrolase, TatD family'
DN752_RS06965	COG1215	transferase activity, transferring glycosyl groups
DN752_RS06975	COG2208	phosphoserine phosphatase activity
DN752_RS06990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DN752_RS06995	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DN752_RS07005	COG0346	lactoylglutathione lyase activity
DN752_RS07015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DN752_RS07020	COG2045	Belongs to the ComB family
DN752_RS07030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DN752_RS07040	COG1694	Mazg nucleotide pyrophosphohydrolase
DN752_RS07045	COG1119	ATPase activity
DN752_RS07050	COG1490	D-aminoacyl-tRNA deacylase activity
DN752_RS07080	COG0316	Belongs to the HesB IscA family
DN752_RS07090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DN752_RS07115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN752_RS07120	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN752_RS07130	COG2235	arginine
DN752_RS07135	COG3590	peptidase
DN752_RS07140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DN752_RS07150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DN752_RS07155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DN752_RS07170	COG0436	Aminotransferase
DN752_RS07175	COG0287	Prephenate dehydrogenase
DN752_RS07180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN752_RS07195	COG0402	S-adenosylhomocysteine deaminase activity
DN752_RS07205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DN752_RS07215	COG4864	UPF0365 protein
DN752_RS07225	COG0442	prolyl-tRNA aminoacylation
DN752_RS07255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN752_RS07260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DN752_RS07265	COG0156	8-amino-7-oxononanoate synthase activity
DN752_RS07270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN752_RS07280	COG1393	Belongs to the ArsC family
DN752_RS07285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DN752_RS07295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DN752_RS07295	COG0519	Catalyzes the synthesis of GMP from XMP
DN752_RS07300	COG0673	inositol 2-dehydrogenase activity
DN752_RS07325	COG2222	sugar isomerase
DN752_RS07335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN752_RS07345	COG0248	Ppx GppA phosphatase
DN752_RS07370	COG0514	ATP-dependent DNA helicase (RecQ)
DN752_RS07375	COG0151	Belongs to the GarS family
DN752_RS07380	COG1774	PSP1 C-terminal conserved region
DN752_RS07390	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DN752_RS07390	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DN752_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS07400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DN752_RS07450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DN752_RS07455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN752_RS07460	COG2239	Acts as a magnesium transporter
DN752_RS07465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DN752_RS07470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DN752_RS07475	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DN752_RS07485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DN752_RS07500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN752_RS07505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DN752_RS07510	COG0511	ligase activity, forming carbon-carbon bonds
DN752_RS07515	COG0439	Biotin carboxylase
DN752_RS07560	COG0022	dehydrogenase e1 component
DN752_RS07565	COG0686	Belongs to the AlaDH PNT family
DN752_RS07570	COG2986	histidine ammonia-lyase
DN752_RS07575	COG0583	DNA-binding transcription factor activity
DN752_RS07580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DN752_RS07590	COG1349	DNA-binding transcription factor activity
DN752_RS07620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN752_RS07620	COG0352	thiamine-phosphate diphosphorylase activity
DN752_RS07620	COG0351	phosphomethylpyrimidine kinase
DN752_RS07625	COG0351	phosphomethylpyrimidine kinase
DN752_RS07630	COG0352	thiamine-phosphate diphosphorylase activity
DN752_RS07635	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DN752_RS07640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN752_RS07650	COG1045	serine acetyltransferase
DN752_RS07665	COG0148	phosphopyruvate hydratase activity
DN752_RS07670	COG0505	Belongs to the CarA family
DN752_RS07675	COG0203	ribosomal protein L17
DN752_RS07680	COG0202	RNA polymerase activity
DN752_RS07685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DN752_RS07690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DN752_RS07695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DN752_RS07700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN752_RS07705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DN752_RS07715	COG0201	protein transport
DN752_RS07720	COG0200	Binds to the 23S rRNA
DN752_RS07730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DN752_RS07735	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DN752_RS07740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DN752_RS07745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DN752_RS07750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DN752_RS07755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DN752_RS07760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DN752_RS07765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DN752_RS07770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DN752_RS07775	COG0255	Belongs to the universal ribosomal protein uL29 family
DN752_RS07780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DN752_RS07785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DN752_RS07790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DN752_RS07795	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DN752_RS07800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DN752_RS07805	COG0089	rRNA binding
DN752_RS07810	COG0088	Forms part of the polypeptide exit tunnel
DN752_RS07815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DN752_RS07820	COG0051	transcription antitermination factor activity, RNA binding
DN752_RS07825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DN752_RS07830	COG0049	tRNA binding
DN752_RS07835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DN752_RS07845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DN752_RS07850	COG0085	RNA polymerase activity
DN752_RS07855	COG0222	ribosome binding
DN752_RS07860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DN752_RS07865	COG0081	regulation of translation
DN752_RS07870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DN752_RS07915	COG0511	ligase activity, forming carbon-carbon bonds
DN752_RS07920	COG0528	UMP kinase activity
DN752_RS07925	COG0233	cytoplasmic translational termination
DN752_RS07935	COG1629	transport
DN752_RS07935	COG4206	TonB-dependent receptor
DN752_RS07955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DN752_RS07960	COG0194	GDP metabolic process
DN752_RS07985	COG0210	DNA helicase
DN752_RS07995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DN752_RS08020	COG4555	ABC transporter
DN752_RS08025	COG0300	oxidoreductase activity
DN752_RS08030	COG1473	amidohydrolase
DN752_RS08035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN752_RS08040	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DN752_RS08050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN752_RS08065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DN752_RS08070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DN752_RS08075	COG0772	Belongs to the SEDS family
DN752_RS08080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DN752_RS08085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN752_RS08090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DN752_RS08095	COG0768	penicillin binding
DN752_RS08105	COG0275	rRNA processing
DN752_RS08110	COG2001	Belongs to the MraZ family
DN752_RS08130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DN752_RS08155	COG0497	DNA recombination
DN752_RS08180	COG0501	Belongs to the peptidase M48B family
DN752_RS08195	COG3022	response to hydroperoxide
DN752_RS08200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DN752_RS08210	COG0126	phosphoglycerate kinase activity
DN752_RS08215	COG0009	L-threonylcarbamoyladenylate synthase
DN752_RS08245	COG0658	competence protein
DN752_RS08245	COG2333	competence protein COMEC
DN752_RS08345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN752_RS08370	COG0542	response to heat
DN752_RS08380	COG0009	L-threonylcarbamoyladenylate synthase
DN752_RS08385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN752_RS08430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DN752_RS08435	COG0732	type I restriction modification DNA specificity domain
DN752_RS08520	COG2003	Belongs to the UPF0758 family
DN752_RS08535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN752_RS08650	COG0702	epimerase
DN752_RS08655	COG1629	transport
DN752_RS08665	COG1595	DNA-templated transcription, initiation
DN752_RS08675	COG1629	transport
DN752_RS08675	COG4206	TonB-dependent receptor
DN752_RS08690	COG0667	Aldo Keto reductase
DN752_RS08700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DN752_RS08725	COG0673	inositol 2-dehydrogenase activity
DN752_RS08730	COG2884	Cell division ATP-binding protein ftsE
DN752_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
DN752_RS08770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS08800	COG1629	transport
DN752_RS08845	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS08855	COG0584	glycerophosphoryl diester phosphodiesterase
DN752_RS08900	COG2197	response regulator
DN752_RS08905	COG1063	alcohol dehydrogenase
DN752_RS08910	COG0738	Major facilitator superfamily
DN752_RS08920	COG1609	Transcriptional regulator
DN752_RS08925	COG0513	Belongs to the DEAD box helicase family
DN752_RS08930	COG0668	transmembrane transport
DN752_RS08945	COG1082	Xylose isomerase domain protein TIM barrel
DN752_RS08955	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS08970	COG4771	TonB-dependent receptor
DN752_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
DN752_RS09040	COG1858	cytochrome C peroxidase
DN752_RS09045	COG1538	Outer membrane efflux protein
DN752_RS09090	COG4771	TonB-dependent receptor
DN752_RS09105	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN752_RS09105	COG1024	Enoyl-CoA hydratase
DN752_RS09130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DN752_RS09130	COG3264	Mechanosensitive ion channel
DN752_RS09140	COG0071	Belongs to the small heat shock protein (HSP20) family
DN752_RS09145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN752_RS09155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN752_RS09175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN752_RS09180	COG0673	inositol 2-dehydrogenase activity
DN752_RS09185	COG4771	TonB-dependent receptor
DN752_RS09190	COG0702	epimerase
DN752_RS09210	COG0552	protein localization to endoplasmic reticulum
DN752_RS09220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DN752_RS09225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DN752_RS09230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN752_RS09240	COG0113	porphobilinogen synthase activity
DN752_RS09245	COG0004	ammonium transporteR
DN752_RS09260	COG3119	arylsulfatase activity
DN752_RS09270	COG0564	pseudouridine synthase activity
DN752_RS09275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DN752_RS09280	COG3852	Histidine kinase
DN752_RS09285	COG0783	Belongs to the Dps family
DN752_RS09290	COG1668	transmembrane transport
DN752_RS09295	COG4152	abc transporter atp-binding protein
DN752_RS09305	COG0484	heat shock protein binding
DN752_RS09310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DN752_RS09315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DN752_RS09320	COG0563	adenylate kinase activity
DN752_RS09325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DN752_RS09340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DN752_RS09385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DN752_RS09390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DN752_RS09395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DN752_RS09400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DN752_RS09405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DN752_RS09415	COG0356	it plays a direct role in the translocation of protons across the membrane
DN752_RS09445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DN752_RS09450	COG0322	excinuclease ABC activity
DN752_RS09470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DN752_RS09495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN752_RS09525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN752_RS09540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DN752_RS09550	COG0564	pseudouridine synthase activity
DN752_RS09555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DN752_RS09565	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DN752_RS09570	COG2807	transmembrane transport
DN752_RS09575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DN752_RS09600	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN752_RS09605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DN752_RS09615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DN752_RS09635	COG1610	YqeY-like protein
DN752_RS09640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DN752_RS09645	COG0596	Alpha beta hydrolase
DN752_RS09650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN752_RS09670	COG0142	geranyltranstransferase activity
DN752_RS09675	COG0557	exoribonuclease II activity
DN752_RS09690	COG0321	lipoyl(octanoyl) transferase activity
DN752_RS09705	COG0792	nuclease activity
DN752_RS09715	COG0436	Aminotransferase
DN752_RS09725	COG1215	transferase activity, transferring glycosyl groups
DN752_RS09750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN752_RS09760	COG3275	phosphorelay sensor kinase activity
DN752_RS09765	COG3279	Response regulator of the LytR AlgR family
DN752_RS09770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DN752_RS09775	COG0423	glycine-tRNA ligase activity
DN752_RS09800	COG1181	Belongs to the D-alanine--D-alanine ligase family
DN752_RS09805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DN752_RS09830	COG1085	galactose-1-phosphate uridylyltransferase
DN752_RS09835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DN752_RS09845	COG1609	Transcriptional regulator
DN752_RS09850	COG2234	aminopeptidase activity
DN752_RS09855	COG0215	cysteine-tRNA ligase activity
DN752_RS09880	COG0779	Required for maturation of 30S ribosomal subunits
DN752_RS09885	COG0195	Participates in both transcription termination and antitermination
DN752_RS09885	COG2251	uridine kinase activity
DN752_RS09890	COG5180	pathogenesis
DN752_RS09890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DN752_RS09910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN752_RS09930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN752_RS09935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DN752_RS09940	COG1187	pseudouridine synthase activity
DN752_RS09950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN752_RS09970	COG1595	DNA-templated transcription, initiation
DN752_RS09985	COG0247	lactate metabolic process
DN752_RS09985	COG2181	nitrate reductase activity
DN752_RS09990	COG2181	nitrate reductase activity
DN752_RS09990	COG0247	lactate metabolic process
DN752_RS10005	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DN752_RS10035	COG1960	acyl-CoA dehydrogenase activity
DN752_RS10045	COG0657	acetylesterase activity
DN752_RS10045	COG2755	lipolytic protein G-D-S-L family
DN752_RS10050	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN752_RS10065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DN752_RS10065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DN752_RS10075	COG0513	Belongs to the DEAD box helicase family
DN752_RS10100	COG0438	transferase activity, transferring glycosyl groups
DN752_RS10110	COG0542	response to heat
DN752_RS10120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DN752_RS10130	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DN752_RS10150	COG2871	sodium ion transport
DN752_RS10155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DN752_RS10165	COG1966	Carbon starvation protein
DN752_RS10195	COG1629	transport
DN752_RS10210	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN752_RS10220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN752_RS10225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN752_RS10240	COG0438	transferase activity, transferring glycosyl groups
DN752_RS10245	COG1472	Belongs to the glycosyl hydrolase 3 family
DN752_RS10255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DN752_RS10275	COG0514	ATP-dependent DNA helicase (RecQ)
DN752_RS10290	COG4771	TonB-dependent receptor
DN752_RS10300	COG4771	TonB-dependent receptor
DN752_RS10350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN752_RS10355	COG1960	acyl-CoA dehydrogenase activity
DN752_RS10360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DN752_RS10365	COG4974	Belongs to the 'phage' integrase family
DN752_RS10420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DN752_RS10430	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DN752_RS10455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN752_RS10460	COG2154	pterin-4-alpha-carbinolamine dehydratase
DN752_RS10470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN752_RS10475	COG1253	flavin adenine dinucleotide binding
DN752_RS10500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DN752_RS10505	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DN752_RS10525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN752_RS10530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN752_RS10560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DN752_RS10575	COG1233	COG1233 Phytoene dehydrogenase and related
DN752_RS10580	COG1595	DNA-templated transcription, initiation
DN752_RS10590	COG1477	protein flavinylation
DN752_RS10595	COG2255	four-way junction helicase activity
DN752_RS10600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DN752_RS10615	COG1138	Cytochrome C-type biogenesis protein
DN752_RS10635	COG0105	UTP biosynthetic process
DN752_RS10640	COG2404	hydrolase activity, acting on ester bonds
DN752_RS10650	COG0545	Peptidyl-prolyl cis-trans isomerase
DN752_RS10655	COG0545	Peptidyl-prolyl cis-trans isomerase
DN752_RS10660	COG1573	uracil-dna glycosylase
DN752_RS10675	COG4771	TonB-dependent receptor
DN752_RS10680	COG0702	epimerase
DN752_RS10685	COG1959	2 iron, 2 sulfur cluster binding
DN752_RS10695	COG0175	sulfate reduction
DN752_RS10700	COG0175	sulfate reduction
DN752_RS10705	COG2895	sulfate adenylyltransferase (ATP) activity
DN752_RS10710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN752_RS10715	COG1648	precorrin-2 dehydrogenase activity
DN752_RS10715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN752_RS10720	COG1648	precorrin-2 dehydrogenase activity
DN752_RS10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN752_RS10725	COG4771	TonB-dependent receptor
DN752_RS10735	COG3511	phospholipase C
DN752_RS10740	COG3250	beta-galactosidase activity
DN752_RS10750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS10765	COG3395	kinase activity
DN752_RS10770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DN752_RS10775	COG1454	alcohol dehydrogenase
DN752_RS10780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS10785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN752_RS10790	COG3408	Glycogen debranching enzyme
DN752_RS10850	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DN752_RS10860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN752_RS10860	COG1918	ferrous iron import across plasma membrane
DN752_RS10880	COG0463	Glycosyl transferase, family 2
DN752_RS10885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DN752_RS10890	COG3119	arylsulfatase activity
DN752_RS10900	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DN752_RS10905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DN752_RS10930	COG3152	Membrane
DN752_RS10935	COG0519	Catalyzes the synthesis of GMP from XMP
DN752_RS10940	COG3119	arylsulfatase activity
DN752_RS10970	COG0110	maltose O-acetyltransferase activity
DN752_RS11020	COG0702	epimerase
DN752_RS11025	COG4206	TonB-dependent receptor
DN752_RS11025	COG1629	transport
DN752_RS11035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DN752_RS11055	COG1595	DNA-templated transcription, initiation
DN752_RS11070	COG4206	TonB-dependent receptor
DN752_RS11070	COG1629	transport
DN752_RS11075	COG0798	PFAM Bile acid sodium symporter
DN752_RS11100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DN752_RS11135	COG0534	Mate efflux family protein
DN752_RS11180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DN752_RS11185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DN752_RS11200	COG1858	cytochrome C peroxidase
DN752_RS11205	COG1956	GAF domain-containing protein
DN752_RS11210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN752_RS11210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN752_RS11235	COG1381	Involved in DNA repair and RecF pathway recombination
DN752_RS11260	COG0772	Belongs to the SEDS family
DN752_RS11265	COG0768	penicillin binding
DN752_RS11280	COG1077	Cell shape determining protein MreB Mrl
DN752_RS11290	COG0138	bifunctional purine biosynthesis protein purh
DN752_RS11300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DN752_RS11330	COG4584	PFAM Integrase catalytic
DN752_RS11335	COG1484	DNA-dependent DNA replication
DN752_RS11345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DN752_RS11350	COG1160	GTP binding
DN752_RS11375	COG0778	Nitroreductase
DN752_RS11380	COG1733	regulation of RNA biosynthetic process
DN752_RS11390	COG4191	Histidine kinase
DN752_RS11420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DN752_RS11425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN752_RS11435	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DN752_RS11445	COG3119	arylsulfatase activity
DN752_RS11445	COG3408	Glycogen debranching enzyme
DN752_RS11450	COG3005	denitrification pathway
DN752_RS11455	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DN752_RS11460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN752_RS11460	COG1333	cytochrome c biogenesis protein
DN752_RS11465	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DN752_RS11485	COG0640	Transcriptional regulator
DN752_RS11495	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS11500	COG0156	8-amino-7-oxononanoate synthase activity
DN752_RS11545	COG0501	Belongs to the peptidase M48B family
DN752_RS11560	COG3239	Fatty acid desaturase
DN752_RS11570	COG1187	pseudouridine synthase activity
DN752_RS11585	COG0668	transmembrane transport
DN752_RS11610	COG0673	inositol 2-dehydrogenase activity
DN752_RS11615	COG3842	ATPase activity
DN752_RS11625	COG2318	DinB family
DN752_RS11630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN752_RS11645	COG1401	restriction endodeoxyribonuclease activity
DN752_RS11650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN752_RS11655	COG0432	Pfam Uncharacterised protein family UPF0047
DN752_RS11660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DN752_RS11665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN752_RS11665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN752_RS11680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DN752_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS11725	COG3119	arylsulfatase activity
DN752_RS11745	COG0708	Exodeoxyribonuclease III
DN752_RS11755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DN752_RS11760	COG0445	tRNA wobble uridine modification
DN752_RS11795	COG3361	conserved protein (COG2071)
DN752_RS11815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DN752_RS11825	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN752_RS11825	COG1024	Enoyl-CoA hydratase
DN752_RS11835	COG0183	Belongs to the thiolase family
DN752_RS11845	COG1960	acyl-CoA dehydrogenase activity
DN752_RS11890	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DN752_RS11905	COG0110	maltose O-acetyltransferase activity
DN752_RS11915	COG4251	negative regulation of phosphorylation
DN752_RS11935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN752_RS11940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DN752_RS11940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DN752_RS11955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN752_RS11965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DN752_RS11970	COG0805	protein transport
DN752_RS11975	COG0698	ribose 5-phosphate isomerase
DN752_RS11990	COG0572	uridine kinase
DN752_RS11995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DN752_RS12005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN752_RS12025	COG4585	Histidine kinase
DN752_RS12030	COG2197	response regulator
DN752_RS12035	COG0673	inositol 2-dehydrogenase activity
DN752_RS12050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DN752_RS12060	COG0157	Belongs to the NadC ModD family
DN752_RS12075	COG1132	(ABC) transporter
DN752_RS12085	COG0702	epimerase
DN752_RS12090	COG4771	TonB-dependent receptor
DN752_RS12135	COG1696	Membrane protein involved in D-alanine export
DN752_RS12155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN752_RS12165	COG1506	peptidase
DN752_RS12180	COG0006	proline dipeptidase activity
DN752_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN752_RS12215	COG0019	diaminopimelate decarboxylase activity
DN752_RS12240	COG1979	alcohol dehydrogenase
DN752_RS12245	COG4303	Ethanolamine ammonia lyase large subunit
DN752_RS12255	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DN752_RS12270	COG2855	membrane
DN752_RS12275	COG0583	DNA-binding transcription factor activity
DN752_RS12305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN752_RS12310	COG0673	inositol 2-dehydrogenase activity
DN752_RS12335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN752_RS12340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN752_RS12365	COG1809	phosphosulfolactate synthase activity
DN752_RS12375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DN752_RS12390	COG1012	belongs to the aldehyde dehydrogenase family
DN752_RS12395	COG1011	Hydrolase
DN752_RS12400	COG0640	Transcriptional regulator
DN752_RS12410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN752_RS12415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS12440	COG2176	DNA-directed DNA polymerase activity
DN752_RS12450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN752_RS12455	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS12465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN752_RS12470	COG0367	asparagine synthase
DN752_RS12485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN752_RS12490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN752_RS12495	COG1309	transcriptional regulator
DN752_RS12500	COG3119	arylsulfatase activity
DN752_RS12505	COG0561	phosphatase activity
DN752_RS12510	COG4771	TonB-dependent receptor
DN752_RS12520	COG1595	DNA-templated transcription, initiation
DN752_RS12545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DN752_RS12550	COG1530	ribonuclease E activity
DN752_RS12560	COG0776	regulation of translation
DN752_RS12570	COG0629	single-stranded DNA binding
DN752_RS12580	COG0067	glutamate synthase
DN752_RS12580	COG0069	glutamate synthase activity
DN752_RS12580	COG0070	glutamate synthase
DN752_RS12590	COG3119	arylsulfatase activity
DN752_RS12610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS12615	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DN752_RS12620	COG0217	transcriptional regulatory protein
DN752_RS12625	COG1252	NADH dehydrogenase
DN752_RS12655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DN752_RS12670	COG1629	transport
DN752_RS12690	COG1649	PFAM Uncharacterised BCR, COG1649
DN752_RS12705	COG3940	Belongs to the glycosyl hydrolase 43 family
DN752_RS12710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN752_RS12720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DN752_RS12725	COG0527	aspartate kinase activity
DN752_RS12740	COG0556	nucleotide-excision repair
DN752_RS12755	COG1960	acyl-CoA dehydrogenase activity
DN752_RS12785	COG1611	Belongs to the LOG family
DN752_RS12805	COG3275	phosphorelay sensor kinase activity
DN752_RS12810	COG3279	Response regulator of the LytR AlgR family
DN752_RS12815	COG0784	Response regulator, receiver
DN752_RS12820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DN752_RS12830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DN752_RS12850	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DN752_RS12850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DN752_RS12855	COG1116	anion transmembrane transporter activity
DN752_RS12860	COG1116	anion transmembrane transporter activity
DN752_RS12865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN752_RS12870	COG1116	anion transmembrane transporter activity
DN752_RS12870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN752_RS12930	COG0517	IMP dehydrogenase activity
DN752_RS12930	COG0516	GMP reductase activity
DN752_RS12950	COG1104	cysteine desulfurase activity
DN752_RS12955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN752_RS12965	COG3956	TIGRFAM MazG family protein
DN752_RS12970	COG2239	Acts as a magnesium transporter
DN752_RS12985	COG5002	protein histidine kinase activity
DN752_RS12995	COG1704	LemA family
DN752_RS13025	COG2264	protein methyltransferase activity
DN752_RS13030	COG0149	triose-phosphate isomerase activity
DN752_RS13035	COG2137	regulation of response to DNA damage stimulus
DN752_RS13045	COG0251	oxidation-reduction process
DN752_RS13065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DN752_RS13065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN752_RS13070	COG1137	ATPase activity
DN752_RS13090	COG0335	large ribosomal subunit rRNA binding
DN752_RS13095	COG0336	Belongs to the RNA methyltransferase TrmD family
DN752_RS13100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DN752_RS13105	COG0228	four-way junction DNA binding
DN752_RS13130	COG1566	PFAM secretion protein HlyD family protein
DN752_RS13135	COG0745	RESPONSE REGULATOR receiver
DN752_RS13140	COG0642	Histidine kinase
DN752_RS13150	COG2003	Belongs to the UPF0758 family
DN752_RS13195	COG4771	TonB-dependent receptor
DN752_RS13250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DN752_RS13305	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DN752_RS13330	COG0653	protein targeting
DN752_RS13335	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DN752_RS13370	COG1309	transcriptional regulator
DN752_RS13375	COG2890	protein-(glutamine-N5) methyltransferase activity
DN752_RS13380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN752_RS13395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DN752_RS13410	COG0662	Cupin 2, conserved barrel domain protein
DN752_RS13415	COG3844	kynureninase activity
DN752_RS13420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN752_RS13440	COG0004	ammonium transporteR
DN752_RS13480	COG1395	domain, Protein
DN752_RS13485	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DN752_RS13500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DN752_RS13505	COG0612	Peptidase, M16
DN752_RS13515	COG2217	Heavy metal translocating P-type atpase
DN752_RS13520	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DN752_RS13525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN752_RS13550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DN752_RS13575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DN752_RS13585	COG0297	glycogen (starch) synthase activity
DN752_RS13590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DN752_RS13595	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DN752_RS13610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN752_RS13630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN752_RS13635	COG0688	phosphatidylethanolamine metabolic process
DN752_RS13650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DN752_RS13655	COG4591	ABC-type transport system involved in lipoprotein release permease component
DN752_RS13665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN752_RS13670	COG0788	formyltetrahydrofolate deformylase activity
DN752_RS13680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN752_RS13685	COG1473	amidohydrolase
DN752_RS13725	COG4977	sequence-specific DNA binding
DN752_RS13740	COG1187	pseudouridine synthase activity
DN752_RS13745	COG0714	Associated with various cellular activities
DN752_RS13775	COG0793	Belongs to the peptidase S41A family
DN752_RS13775	COG4946	Tricorn protease homolog
DN752_RS13780	COG1253	flavin adenine dinucleotide binding
DN752_RS13785	COG0628	permease
DN752_RS13795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN752_RS13800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN752_RS13805	COG0569	domain protein
DN752_RS13810	COG1556	Lactate utilization protein
DN752_RS13815	COG1139	Iron-sulfur cluster binding protein
DN752_RS13820	COG0247	lactate metabolic process
DN752_RS13825	COG1501	Belongs to the glycosyl hydrolase 31 family
DN752_RS13835	COG4952	isomerase
DN752_RS13840	COG1070	Carbohydrate kinase
DN752_RS13850	COG3177	Filamentation induced by cAMP protein fic
DN752_RS13855	COG0673	inositol 2-dehydrogenase activity
DN752_RS13870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DN752_RS13880	COG1283	sodium-dependent phosphate transmembrane transporter activity
DN752_RS13890	COG0590	tRNA wobble adenosine to inosine editing
DN752_RS13925	COG0513	Belongs to the DEAD box helicase family
DN752_RS13930	COG4628	conserved protein (DUF2132)
DN752_RS13940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN752_RS13955	COG1254	Belongs to the acylphosphatase family
DN752_RS13975	COG1090	epimerase
DN752_RS13980	COG0038	chloride channel
DN752_RS13985	COG1609	Transcriptional regulator
DN752_RS13990	COG2755	lipolytic protein G-D-S-L family
DN752_RS13990	COG0657	acetylesterase activity
DN752_RS14005	COG1609	Transcriptional regulator
DN752_RS14015	COG3254	rhamnose metabolic process
DN752_RS14020	COG4771	TonB-dependent receptor
DN752_RS14025	COG0702	epimerase
DN752_RS14040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN752_RS14045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN752_RS14070	COG2755	lipolytic protein G-D-S-L family
DN752_RS14075	COG2353	YceI-like domain
DN752_RS14090	COG4181	ATPase activity
DN752_RS14120	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DN752_RS14130	COG1629	transport
DN752_RS14150	COG0726	polysaccharide deacetylase
DN752_RS14150	COG1649	PFAM Uncharacterised BCR, COG1649
DN752_RS14160	COG3458	cephalosporin-C deacetylase activity
DN752_RS14165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS14170	COG0745	RESPONSE REGULATOR receiver
DN752_RS14170	COG2205	protein histidine kinase activity
DN752_RS14170	COG3292	Two component regulator propeller
DN752_RS14185	COG4771	TonB-dependent receptor
DN752_RS14190	COG0702	epimerase
DN752_RS14205	COG4206	TonB-dependent receptor
DN752_RS14205	COG1629	transport
DN752_RS14220	COG3401	FG-GAP repeat protein
DN752_RS14240	COG2755	lipolytic protein G-D-S-L family
DN752_RS14270	COG3250	beta-galactosidase activity
DN752_RS14275	COG3250	beta-galactosidase activity
DN752_RS14285	COG1629	transport
DN752_RS14295	COG4771	TonB-dependent receptor
DN752_RS14300	COG0702	epimerase
DN752_RS14310	COG1501	Belongs to the glycosyl hydrolase 31 family
DN752_RS14315	COG0673	inositol 2-dehydrogenase activity
DN752_RS14325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS14335	COG3250	beta-galactosidase activity
DN752_RS14375	COG0385	Bile acid
DN752_RS14385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN752_RS14395	COG3250	beta-galactosidase activity
DN752_RS14400	COG3940	Belongs to the glycosyl hydrolase 43 family
DN752_RS14435	COG0419	ATPase involved in DNA repair
DN752_RS14440	COG0420	3'-5' exonuclease activity
DN752_RS14445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DN752_RS14450	COG3781	membrane
DN752_RS14525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN752_RS14585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DN752_RS14605	COG1132	(ABC) transporter
DN752_RS14610	COG0101	tRNA pseudouridine synthase activity
DN752_RS14645	COG0626	cystathionine gamma-synthase activity
DN752_RS14650	COG0606	chelatase, subunit chli
DN752_RS14660	COG1132	(ABC) transporter
DN752_RS14670	COG0254	rRNA binding
DN752_RS14680	COG0470	DNA polymerase III
DN752_RS14695	COG0181	hydroxymethylbilane synthase activity
DN752_RS14700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN752_RS14710	COG1115	amino acid carrier protein
DN752_RS14720	COG2207	Transcriptional regulator
DN752_RS14725	COG0022	dehydrogenase e1 component
DN752_RS14730	COG3217	Mosc domain protein beta barrel domain protein
DN752_RS14730	COG0633	Ferredoxin
DN752_RS14740	COG0443	Heat shock 70 kDa protein
DN752_RS14750	COG1132	(ABC) transporter
DN752_RS14760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DN752_RS14775	COG1862	Preprotein translocase
DN752_RS14785	COG0237	dephospho-CoA kinase activity
DN752_RS14795	COG0791	NLP P60 protein
DN752_RS14800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DN752_RS14815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DN752_RS14820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DN752_RS14835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN752_RS14835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DN752_RS14840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN752_RS14850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DN752_RS14855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DN752_RS14885	COG0612	Peptidase, M16
DN752_RS14905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DN752_RS14910	COG0594	ribonuclease P activity
DN752_RS14915	COG0793	Belongs to the peptidase S41A family
DN752_RS14920	COG1214	PFAM Peptidase M22, glycoprotease
DN752_RS14960	COG4221	oxidoreductase activity
DN752_RS14980	COG0295	cytidine deaminase activity
DN752_RS14990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DN752_RS14995	COG0328	RNA-DNA hybrid ribonuclease activity
DN752_RS15000	COG2095	MarC family integral membrane protein
DN752_RS15010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DN752_RS15030	COG0702	epimerase
DN752_RS15035	COG4771	TonB-dependent receptor
DN752_RS15045	COG0167	dihydroorotate dehydrogenase activity
DN752_RS15050	COG1674	ftsk spoiiie
DN752_RS15060	COG0284	orotidine-5'-phosphate decarboxylase activity
DN752_RS15075	COG1054	Belongs to the UPF0176 family
DN752_RS15080	COG0813	purine-nucleoside phosphorylase activity
DN752_RS15085	COG2072	flavoprotein involved in K transport
DN752_RS15090	COG0488	(ABC) transporter
DN752_RS15105	COG2226	methyltransferase
DN752_RS15110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DN752_RS15125	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DN752_RS15130	COG0527	aspartate kinase activity
DN752_RS15140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DN752_RS15155	COG0450	alkyl hydroperoxide reductase
DN752_RS15165	COG1162	GTPase activity
DN752_RS15175	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DN752_RS15180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DN752_RS15205	COG0673	inositol 2-dehydrogenase activity
DN752_RS15210	COG2211	Major facilitator Superfamily
DN752_RS15215	COG1082	Xylose isomerase domain protein TIM barrel
DN752_RS15230	COG1082	Xylose isomerase domain protein TIM barrel
DN752_RS15260	COG2234	aminopeptidase activity
DN752_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS15280	COG3661	Belongs to the glycosyl hydrolase 67 family
DN752_RS15285	COG1609	Transcriptional regulator
DN752_RS15290	COG4771	TonB-dependent receptor
DN752_RS15295	COG0702	epimerase
DN752_RS15305	COG1312	Catalyzes the dehydration of D-mannonate
DN752_RS15325	COG2161	toxin-antitoxin pair type II binding
DN752_RS15335	COG0514	ATP-dependent DNA helicase (RecQ)
DN752_RS15355	COG1070	Carbohydrate kinase
DN752_RS15360	COG2115	Belongs to the xylose isomerase family
DN752_RS15375	COG2160	L-arabinose isomerase activity
DN752_RS15395	COG0793	Belongs to the peptidase S41A family
DN752_RS15405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DN752_RS15410	COG0242	peptide deformylase activity
DN752_RS15415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN752_RS15425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN752_RS15430	COG0303	'Molybdopterin
DN752_RS15435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN752_RS15440	COG0315	cyclic pyranopterin monophosphate synthase activity
DN752_RS15440	COG0746	molybdenum cofactor guanylyltransferase activity
DN752_RS15445	COG0315	cyclic pyranopterin monophosphate synthase activity
DN752_RS15450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN752_RS15455	COG0314	molybdopterin synthase activity
DN752_RS15465	COG2197	response regulator
DN752_RS15470	COG4585	Histidine kinase
DN752_RS15485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN752_RS15485	COG2146	nitrite reductase [NAD(P)H] activity
DN752_RS15540	COG0243	molybdopterin cofactor binding
DN752_RS15545	COG2223	nitrite transmembrane transporter activity
DN752_RS15555	COG0561	phosphatase activity
DN752_RS15580	COG1289	transmembrane transporter activity
DN752_RS15585	COG0673	inositol 2-dehydrogenase activity
DN752_RS15600	COG4206	TonB-dependent receptor
DN752_RS15600	COG1629	transport
DN752_RS15625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DN752_RS15635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS15650	COG0668	transmembrane transport
DN752_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS15675	COG0527	aspartate kinase activity
DN752_RS15675	COG0460	homoserine dehydrogenase
DN752_RS15680	COG0083	homoserine kinase activity
DN752_RS15685	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DN752_RS15710	COG0492	ferredoxin-NADP+ reductase activity
DN752_RS15715	COG2205	protein histidine kinase activity
DN752_RS15720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DN752_RS15725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DN752_RS15730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DN752_RS15735	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN752_RS15740	COG1805	sodium ion transport
DN752_RS15750	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN752_RS15755	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN752_RS15765	COG3118	belongs to the thioredoxin family
DN752_RS15780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DN752_RS15790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN752_RS15795	COG1649	PFAM Uncharacterised BCR, COG1649
DN752_RS15800	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DN752_RS15815	COG2197	response regulator
DN752_RS15825	COG0330	HflC and HflK could
DN752_RS15830	COG0330	HflC and HflK could
DN752_RS15835	COG1629	transport
DN752_RS15850	COG3250	beta-galactosidase activity
DN752_RS15850	COG5297	Belongs to the glycosyl hydrolase family 6
DN752_RS15855	COG1472	Belongs to the glycosyl hydrolase 3 family
DN752_RS15860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DN752_RS15865	COG3876	Protein conserved in bacteria
DN752_RS15880	COG3387	PFAM Glycoside hydrolase 15-related
DN752_RS15885	COG0357	Ribosomal RNA small subunit methyltransferase G
DN752_RS15890	COG1595	DNA-templated transcription, initiation
DN752_RS15900	COG0343	queuine tRNA-ribosyltransferase activity
DN752_RS15915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DN752_RS15920	COG0129	dihydroxy-acid dehydratase activity
DN752_RS15925	COG0028	Belongs to the TPP enzyme family
DN752_RS15935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DN752_RS15940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DN752_RS15945	COG0066	3-isopropylmalate dehydratase activity
DN752_RS15965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DN752_RS15975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DN752_RS15980	COG0497	DNA recombination
DN752_RS16000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN752_RS16015	COG0037	tRNA processing
DN752_RS16025	COG0039	L-malate dehydrogenase activity
DN752_RS16035	COG0668	transmembrane transport
DN752_RS16050	COG0626	cystathionine gamma-synthase activity
DN752_RS16065	COG0415	Belongs to the DNA photolyase family
DN752_RS16075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DN752_RS16080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DN752_RS16100	COG2610	gluconate transmembrane transporter activity
DN752_RS16125	COG0539	negative regulation of cytoplasmic translation
DN752_RS16145	COG2010	Cytochrome c
DN752_RS16175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DN752_RS16180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN752_RS16185	COG1612	heme a metabolic process
DN752_RS16190	COG0109	protoheme IX farnesyltransferase activity
DN752_RS16195	COG1845	cytochrome c oxidase, subunit III
DN752_RS16200	COG1845	cytochrome c oxidase, subunit III
DN752_RS16210	COG1999	signal sequence binding
DN752_RS16215	COG2322	membrane
DN752_RS16225	COG5000	phosphorelay sensor kinase activity
DN752_RS16275	COG4221	oxidoreductase activity
DN752_RS16280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DN752_RS16295	COG3842	ATPase activity
DN752_RS16305	COG0495	leucyl-tRNA aminoacylation
DN752_RS16320	COG1511	domain protein
DN752_RS16320	COG3264	Mechanosensitive ion channel
DN752_RS16325	COG3153	acetyltransferase
DN752_RS16325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN752_RS16330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DN752_RS16335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DN752_RS16360	COG0302	gtp cyclohydrolase
DN752_RS16375	COG1629	transport
DN752_RS16375	COG4206	TonB-dependent receptor
DN752_RS16380	COG0702	epimerase
DN752_RS16410	COG3119	arylsulfatase activity
DN752_RS16420	COG3250	beta-galactosidase activity
DN752_RS16430	COG4771	TonB-dependent receptor
DN752_RS16465	COG2205	protein histidine kinase activity
DN752_RS16485	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DN752_RS16490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS16495	COG1595	DNA-templated transcription, initiation
DN752_RS16505	COG4771	TonB-dependent receptor
DN752_RS16515	COG5492	domain, Protein
DN752_RS16525	COG3119	arylsulfatase activity
DN752_RS16530	COG1595	DNA-templated transcription, initiation
DN752_RS16545	COG4771	TonB-dependent receptor
DN752_RS16550	COG0702	epimerase
DN752_RS16555	COG3119	arylsulfatase activity
DN752_RS16560	COG3119	arylsulfatase activity
DN752_RS16585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN752_RS16595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DN752_RS16600	COG0456	acetyltransferase
DN752_RS16620	COG1522	sequence-specific DNA binding
DN752_RS16625	COG0494	nUDIX hydrolase
DN752_RS16630	COG0534	Mate efflux family protein
DN752_RS16635	COG1607	acyl-coa hydrolase
DN752_RS16640	COG2814	Major facilitator Superfamily
DN752_RS16655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN752_RS16660	COG2096	Adenosyltransferase
DN752_RS16665	COG1136	(ABC) transporter
DN752_RS16675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DN752_RS16685	COG2346	COG2346, Truncated hemoglobins
DN752_RS16690	COG1030	water channel activity
DN752_RS16695	COG3942	CHAP domain
DN752_RS16695	COG1388	LysM domain
DN752_RS16715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DN752_RS16720	COG1051	belongs to the nudix hydrolase family
DN752_RS16725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DN752_RS16745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN752_RS16770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN752_RS16780	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN752_RS16785	COG2027	D-alanyl-D-alanine carboxypeptidase
DN752_RS16790	COG2363	Small membrane protein
DN752_RS16795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DN752_RS16870	COG1216	Glycosyl transferase, family 2
DN752_RS16890	COG2304	oxidoreductase activity
DN752_RS16910	COG1193	negative regulation of DNA recombination
DN752_RS16925	COG0488	(ABC) transporter
DN752_RS16930	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN752_RS16935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DN752_RS16935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DN752_RS16940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN752_RS16945	COG1078	dGTPase activity
DN752_RS16950	COG2204	response regulator
DN752_RS16955	COG0802	atpase or kinase
DN752_RS16960	COG0686	Belongs to the AlaDH PNT family
DN752_RS16985	COG2204	response regulator
DN752_RS17005	COG0587	DNA-directed DNA polymerase activity
DN752_RS17015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN752_RS17035	COG0673	inositol 2-dehydrogenase activity
DN752_RS17060	COG0673	inositol 2-dehydrogenase activity
DN752_RS17070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN752_RS17080	COG0730	response to heat
DN752_RS17085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN752_RS17085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN752_RS17145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN752_RS17165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN752_RS17175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DN752_RS17180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DN752_RS17180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN752_RS17185	COG0571	ribonuclease III activity
DN752_RS17190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN752_RS17195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN752_RS17205	COG0469	pyruvate kinase activity
DN752_RS17215	COG0321	lipoyl(octanoyl) transferase activity
DN752_RS17215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DN752_RS17225	COG2205	protein histidine kinase activity
DN752_RS17225	COG0784	Response regulator, receiver
DN752_RS17230	COG4999	Histidine kinase
DN752_RS17230	COG3850	Histidine kinase
DN752_RS17230	COG3437	response regulator, receiver
DN752_RS17230	COG2205	protein histidine kinase activity
DN752_RS17235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DN752_RS17245	COG0205	6-phosphofructokinase activity
DN752_RS17265	COG1088	dTDP-glucose 4,6-dehydratase activity
DN752_RS17290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN752_RS17290	COG4451	ribulose bisphosphate carboxylase, small
DN752_RS17300	COG1271	oxidase subunit
DN752_RS17330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DN752_RS17335	COG1169	isochorismate synthase
DN752_RS17340	COG2050	protein possibly involved in aromatic compounds catabolism
DN752_RS17345	COG0406	alpha-ribazole phosphatase activity
DN752_RS17360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN752_RS17365	COG1663	tetraacyldisaccharide 4'-kinase activity
DN752_RS17380	COG0577	efflux transmembrane transporter activity
DN752_RS17415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN752_RS17445	COG0346	lactoylglutathione lyase activity
DN752_RS17450	COG0598	Magnesium transport protein CorA
DN752_RS17455	COG2201	protein-glutamate methylesterase activity
DN752_RS17460	COG0459	protein refolding
DN752_RS17465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DN752_RS17500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN752_RS17515	COG0205	6-phosphofructokinase activity
DN752_RS17520	COG1803	Methylglyoxal synthase
DN752_RS17525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN752_RS17530	COG1331	Highly conserved protein containing a thioredoxin domain
DN752_RS17545	COG0359	binds to the 23S rRNA
DN752_RS17550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DN752_RS17555	COG0360	Binds together with S18 to 16S ribosomal RNA
DN752_RS17580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DN752_RS17585	COG0681	Belongs to the peptidase S26 family
DN752_RS17590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DN752_RS17600	COG1475	DNA binding
DN752_RS17605	COG1192	Involved in chromosome partitioning
DN752_RS17610	COG0706	membrane insertase activity
DN752_RS17615	COG0504	CTP synthase activity
DN752_RS17630	COG0517	IMP dehydrogenase activity
DN752_RS17630	COG0617	tRNA 3'-terminal CCA addition
DN752_RS17630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DN752_RS17645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN752_RS17665	COG0456	acetyltransferase
DN752_RS17810	COG2135	peptidase activity
DN752_RS17850	COG2003	Belongs to the UPF0758 family
DN752_RS17885	COG0740	serine-type endopeptidase activity
DN752_RS17965	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DN752_RS18050	COG4771	TonB-dependent receptor
DN752_RS18070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DN752_RS18090	COG4191	Histidine kinase
DN752_RS18100	COG1047	Peptidyl-prolyl cis-trans
DN752_RS18115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN752_RS18120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN752_RS18125	COG0799	negative regulation of ribosome biogenesis
DN752_RS18135	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DN752_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS18160	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN752_RS18170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN752_RS18185	COG0427	acetyl-CoA hydrolase
DN752_RS18190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DN752_RS18190	COG1703	isobutyryl-CoA mutase activity
DN752_RS18190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DN752_RS18210	COG2205	protein histidine kinase activity
DN752_RS18210	COG0784	Response regulator, receiver
DN752_RS18215	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN752_RS18220	COG1546	Belongs to the CinA family
DN752_RS18220	COG1058	Belongs to the CinA family
DN752_RS18225	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN752_RS18235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DN752_RS18240	COG3876	Protein conserved in bacteria
DN752_RS18245	COG4591	ABC-type transport system involved in lipoprotein release permease component
DN752_RS18250	COG0463	Glycosyl transferase, family 2
DN752_RS18270	COG0131	Imidazoleglycerol-phosphate dehydratase
DN752_RS18270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DN752_RS18275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DN752_RS18280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DN752_RS18285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DN752_RS18290	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DN752_RS18315	COG1575	Belongs to the MenA family. Type 1 subfamily
DN752_RS18320	COG0386	Belongs to the glutathione peroxidase family
DN752_RS18325	COG0018	arginyl-trna synthetase
DN752_RS18330	COG0010	Belongs to the arginase family
DN752_RS18345	COG1538	Outer membrane efflux protein
DN752_RS18395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN752_RS18405	COG0525	valine-tRNA ligase activity
DN752_RS18425	COG2365	Tyrosine phosphatase family
DN752_RS18445	COG3239	Fatty acid desaturase
DN752_RS18465	COG3119	arylsulfatase activity
DN752_RS18490	COG1629	transport
DN752_RS18510	COG2884	Cell division ATP-binding protein ftsE
DN752_RS18520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN752_RS18540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DN752_RS18550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN752_RS18550	COG0512	Glutamine amidotransferase of anthranilate synthase
DN752_RS18555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN752_RS18560	COG0134	indole-3-glycerol-phosphate synthase activity
DN752_RS18565	COG0135	phosphoribosylanthranilate isomerase activity
DN752_RS18570	COG0133	tryptophan synthase activity
DN752_RS18575	COG0159	tryptophan synthase activity
DN752_RS18580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN752_RS18585	COG3186	Phenylalanine-4-hydroxylase
DN752_RS18590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DN752_RS18595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DN752_RS18600	COG0107	imidazoleglycerol-phosphate synthase activity
DN752_RS18605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DN752_RS18605	COG0140	phosphoribosyl-ATP diphosphatase activity
DN752_RS18635	COG0488	(ABC) transporter
DN752_RS18650	COG0012	GTP binding
DN752_RS18655	COG0628	permease
DN752_RS18665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN752_RS18675	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DN752_RS18690	COG2198	Histidine kinase
DN752_RS18690	COG0784	Response regulator, receiver
DN752_RS18690	COG5002	protein histidine kinase activity
DN752_RS18700	COG1393	Belongs to the ArsC family
DN752_RS18705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN752_RS18710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DN752_RS18715	COG2207	Transcriptional regulator
DN752_RS18715	COG1917	Cupin 2, conserved barrel domain protein
DN752_RS18755	COG1597	lipid kinase activity
DN752_RS18770	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS18785	COG2204	response regulator
DN752_RS18800	COG0745	RESPONSE REGULATOR receiver
DN752_RS18805	COG4251	negative regulation of phosphorylation
DN752_RS18820	COG0753	catalase activity
DN752_RS18825	COG3237	CsbD-like
DN752_RS18845	COG0318	PFAM AMP-dependent synthetase and ligase
DN752_RS18850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DN752_RS18860	COG2176	DNA-directed DNA polymerase activity
DN752_RS18875	COG1607	acyl-coa hydrolase
DN752_RS18880	COG1366	Belongs to the anti-sigma-factor antagonist family
DN752_RS18885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DN752_RS18905	COG0628	permease
DN752_RS18925	COG2234	aminopeptidase activity
DN752_RS18930	COG0339	signal peptide processing
DN752_RS18950	COG4977	sequence-specific DNA binding
DN752_RS19010	COG0529	Catalyzes the synthesis of activated sulfate
DN752_RS19025	COG1216	Glycosyl transferase, family 2
DN752_RS19025	COG0463	Glycosyl transferase, family 2
DN752_RS19040	COG1215	transferase activity, transferring glycosyl groups
DN752_RS19045	COG0463	Glycosyl transferase, family 2
DN752_RS19055	COG0463	Glycosyl transferase, family 2
DN752_RS19055	COG1216	Glycosyl transferase, family 2
DN752_RS19065	COG0438	transferase activity, transferring glycosyl groups
DN752_RS19100	COG2226	methyltransferase
DN752_RS19115	COG3119	arylsulfatase activity
DN752_RS19125	COG0702	epimerase
DN752_RS19130	COG4771	TonB-dependent receptor
DN752_RS19170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS19175	COG0745	RESPONSE REGULATOR receiver
DN752_RS19180	COG5002	protein histidine kinase activity
DN752_RS19200	COG3263	regulation of cellular component size
DN752_RS19230	COG1785	Belongs to the alkaline phosphatase family
DN752_RS19240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN752_RS19245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DN752_RS19250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DN752_RS19255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN752_RS19355	COG1051	belongs to the nudix hydrolase family
DN752_RS19410	COG4771	TonB-dependent receptor
DN752_RS19435	COG4771	TonB-dependent receptor
DN752_RS19460	COG4974	Belongs to the 'phage' integrase family
DN752_RS19585	COG1802	Transcriptional regulator
DN752_RS19585	COG4626	Terminase
DN752_RS19710	COG1011	Hydrolase
DN752_RS19725	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN752_RS19750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DN752_RS19755	COG1607	acyl-coa hydrolase
DN752_RS19760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN752_RS19765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN752_RS19770	COG1063	alcohol dehydrogenase
DN752_RS19785	COG4206	TonB-dependent receptor
DN752_RS19785	COG1629	transport
DN752_RS19800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN752_RS19810	COG3119	arylsulfatase activity
DN752_RS19845	COG4206	TonB-dependent receptor
DN752_RS19850	COG3119	arylsulfatase activity
DN752_RS19900	COG1086	Polysaccharide biosynthesis protein
DN752_RS19905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN752_RS19910	COG1083	cytidylyl-transferase
DN752_RS19920	COG2089	acid synthase
DN752_RS19935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN752_RS19945	COG0438	transferase activity, transferring glycosyl groups
DN752_RS19965	COG1216	Glycosyl transferase, family 2
DN752_RS19970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN752_RS19985	COG1368	sulfuric ester hydrolase activity
DN752_RS19990	COG1396	sequence-specific DNA binding
DN752_RS20000	COG1629	transport
DN752_RS20000	COG4206	TonB-dependent receptor
DN752_RS20005	COG1115	amino acid carrier protein
DN752_RS20020	COG0438	transferase activity, transferring glycosyl groups
DN752_RS20045	COG0463	Glycosyl transferase, family 2
DN752_RS20045	COG1216	Glycosyl transferase, family 2
DN752_RS20050	COG1216	Glycosyl transferase, family 2
DN752_RS20060	COG1132	(ABC) transporter
DN752_RS20070	COG1215	transferase activity, transferring glycosyl groups
DN752_RS20110	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DN752_RS20110	COG2755	lipolytic protein G-D-S-L family
DN752_RS20115	COG1595	DNA-templated transcription, initiation
DN752_RS20135	COG4771	TonB-dependent receptor
DN752_RS20145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN752_RS20155	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DN752_RS20165	COG0745	RESPONSE REGULATOR receiver
DN752_RS20165	COG2205	protein histidine kinase activity
DN752_RS20165	COG3292	Two component regulator propeller
DN752_RS20170	COG4206	TonB-dependent receptor
DN752_RS20170	COG1629	transport
DN752_RS20185	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS20205	COG3250	beta-galactosidase activity
DN752_RS20235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN752_RS20265	COG0616	signal peptide processing
DN752_RS20275	COG0534	Mate efflux family protein
DN752_RS20290	COG2267	carboxylic ester hydrolase activity
DN752_RS20300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN752_RS20305	COG3011	Protein conserved in bacteria
DN752_RS20320	COG1053	succinate dehydrogenase
DN752_RS20325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN752_RS20340	COG3457	Alanine racemase
DN752_RS20355	COG0673	inositol 2-dehydrogenase activity
DN752_RS20365	COG2814	Major facilitator Superfamily
DN752_RS20370	COG1621	beta-fructofuranosidase activity
DN752_RS20375	COG1621	beta-fructofuranosidase activity
DN752_RS20385	COG4206	TonB-dependent receptor
DN752_RS20385	COG1629	transport
DN752_RS20390	COG2814	Major facilitator Superfamily
DN752_RS20395	COG2205	protein histidine kinase activity
DN752_RS20395	COG0745	RESPONSE REGULATOR receiver
DN752_RS20395	COG3292	Two component regulator propeller
DN752_RS20410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN752_RS20410	COG0475	glutathione-regulated potassium exporter activity
DN752_RS20425	COG1757	Na H antiporter
DN752_RS20435	COG1739	Uncharacterized protein family UPF0029
DN752_RS20450	COG0463	Glycosyl transferase, family 2
DN752_RS20470	COG1183	phosphatidylcholine synthase activity
DN752_RS20475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN752_RS20480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN752_RS20490	COG1561	YicC-like family, N-terminal region
DN752_RS20495	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DN752_RS20505	COG1760	l-serine dehydratase
DN752_RS20530	COG0590	tRNA wobble adenosine to inosine editing
DN752_RS20535	COG5002	protein histidine kinase activity
DN752_RS20550	COG1609	Transcriptional regulator
DN752_RS20555	COG4206	TonB-dependent receptor
DN752_RS20555	COG1629	transport
DN752_RS20560	COG0702	epimerase
DN752_RS20585	COG1595	DNA-templated transcription, initiation
DN752_RS20595	COG1629	transport
DN752_RS20595	COG4206	TonB-dependent receptor
DN752_RS20620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DN752_RS20645	COG2274	protein secretion by the type I secretion system
DN752_RS20650	COG0698	ribose 5-phosphate isomerase
DN752_RS20655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DN752_RS20660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN752_RS20665	COG0363	glucosamine-6-phosphate deaminase activity
DN752_RS20675	COG0673	inositol 2-dehydrogenase activity
DN752_RS20685	COG2207	Transcriptional regulator
DN752_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS20700	COG0667	Aldo Keto reductase
DN752_RS20705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DN752_RS20705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN752_RS20765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN752_RS20775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN752_RS20785	COG2217	Heavy metal translocating P-type atpase
DN752_RS20805	COG2010	Cytochrome c
DN752_RS20810	COG0348	domain, Protein
DN752_RS20850	COG1609	Transcriptional regulator
DN752_RS20855	COG4206	TonB-dependent receptor
DN752_RS20855	COG1629	transport
DN752_RS20865	COG3119	arylsulfatase activity
DN752_RS20880	COG1566	PFAM secretion protein HlyD family protein
DN752_RS21085	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DN752_RS21175	COG2135	peptidase activity
DN752_RS21190	COG0045	succinate-CoA ligase (ADP-forming) activity
DN752_RS21195	COG1136	(ABC) transporter
DN752_RS21200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN752_RS21210	COG0697	spore germination
DN752_RS21215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DN752_RS21220	COG1335	isochorismatase
DN752_RS21225	COG0384	phenazine biosynthesis protein PhzF
DN752_RS21235	COG0450	alkyl hydroperoxide reductase
DN752_RS21240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN752_RS21245	COG0644	oxidoreductase
DN752_RS21255	COG0673	inositol 2-dehydrogenase activity
DN752_RS21285	COG3958	Transketolase
DN752_RS21290	COG3959	Transketolase, thiamine diphosphate binding domain
DN752_RS21295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN752_RS21305	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN752_RS21310	COG1741	Belongs to the pirin family
DN752_RS21325	COG1132	(ABC) transporter
DN752_RS21350	COG5642	Protein of unknown function (DUF2384)
DN752_RS21360	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN752_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS21370	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS21380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DN752_RS21440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN752_RS21450	COG0305	Participates in initiation and elongation during chromosome replication
DN752_RS21455	COG0604	alcohol dehydrogenase
DN752_RS21470	COG2086	electron transfer activity
DN752_RS21475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DN752_RS21485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN752_RS21490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN752_RS21500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DN752_RS21525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DN752_RS21595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DN752_RS21605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DN752_RS21615	COG0101	tRNA pseudouridine synthase activity
DN752_RS21620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN752_RS21630	COG5492	domain, Protein
DN752_RS21645	COG0180	Tryptophanyl-tRNA synthetase
DN752_RS21665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DN752_RS21675	COG0187	DNA topoisomerase II activity
DN752_RS21695	COG0471	metal ion transport
DN752_RS21695	COG3273	potassium ion transport
DN752_RS21720	COG2382	esterase
DN752_RS21730	COG1984	allophanate hydrolase subunit 2
DN752_RS21735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DN752_RS21740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DN752_RS21745	COG1914	H( )-stimulated, divalent metal cation uptake system
DN752_RS21765	COG0569	domain protein
DN752_RS21770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN752_RS21785	COG2133	pyrroloquinoline quinone binding
DN752_RS21815	COG3530	Putative quorum-sensing-regulated virulence factor
DN752_RS21820	COG1073	alpha beta
DN752_RS21825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN752_RS21835	COG3206	protein involved in exopolysaccharide biosynthesis
DN752_RS21835	COG0489	protein tyrosine kinase activity
DN752_RS21845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN752_RS21850	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DN752_RS21890	COG0110	maltose O-acetyltransferase activity
DN752_RS21905	COG0110	maltose O-acetyltransferase activity
DN752_RS21945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN752_RS21950	COG0024	Methionine aminopeptidase
DN752_RS21955	COG0659	secondary active sulfate transmembrane transporter activity
DN752_RS21970	COG4895	conserved protein (DUF2196)
DN752_RS21980	COG3279	Response regulator of the LytR AlgR family
DN752_RS21985	COG2972	Histidine kinase
DN752_RS22005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN752_RS22010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DN752_RS22015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN752_RS22055	COG1528	Iron-storage protein
DN752_RS22060	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DN752_RS22065	COG2076	Multidrug Resistance protein
DN752_RS22080	COG0513	Belongs to the DEAD box helicase family
DN752_RS22095	COG2151	metal-sulfur cluster biosynthetic enzyme
DN752_RS22100	COG2166	iron-sulfur cluster assembly
DN752_RS22105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN752_RS22110	COG0719	Fe-S assembly protein
DN752_RS22115	COG0396	ATPase activity
DN752_RS22120	COG0719	Fe-S assembly protein
DN752_RS22125	COG1522	sequence-specific DNA binding
DN752_RS22155	COG0640	Transcriptional regulator
DN752_RS22160	COG0110	maltose O-acetyltransferase activity
DN752_RS22185	COG1506	peptidase
DN752_RS22185	COG0823	Involved in the tonB-independent uptake of proteins
DN752_RS22185	COG4946	Tricorn protease homolog
DN752_RS22215	COG0246	Mannitol dehydrogenase
DN752_RS22220	COG1904	glucuronate isomerase
DN752_RS22225	COG1609	Transcriptional regulator
DN752_RS22230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS22250	COG2755	lipolytic protein G-D-S-L family
DN752_RS22255	COG0657	acetylesterase activity
DN752_RS22260	COG4771	TonB-dependent receptor
DN752_RS22300	COG0673	inositol 2-dehydrogenase activity
DN752_RS22315	COG3119	arylsulfatase activity
DN752_RS22350	COG1312	Catalyzes the dehydration of D-mannonate
DN752_RS22355	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS22360	COG1904	glucuronate isomerase
DN752_RS22375	COG4771	TonB-dependent receptor
DN752_RS22380	COG3622	Belongs to the hyi family
DN752_RS22385	COG2378	regulation of single-species biofilm formation
DN752_RS22395	COG4558	Periplasmic binding protein
DN752_RS22400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN752_RS22405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DN752_RS22410	COG3720	iron ion transport
DN752_RS22415	COG4771	TonB-dependent receptor
DN752_RS22435	COG2205	protein histidine kinase activity
DN752_RS22435	COG3292	Two component regulator propeller
DN752_RS22435	COG0745	RESPONSE REGULATOR receiver
DN752_RS22440	COG1629	transport
DN752_RS22445	COG0702	epimerase
DN752_RS22455	COG3250	beta-galactosidase activity
DN752_RS22470	COG3119	arylsulfatase activity
DN752_RS22480	COG3119	arylsulfatase activity
DN752_RS22510	COG3250	beta-galactosidase activity
DN752_RS22515	COG4771	TonB-dependent receptor
DN752_RS22525	COG4771	TonB-dependent receptor
DN752_RS22530	COG0702	epimerase
DN752_RS22540	COG3119	arylsulfatase activity
DN752_RS22550	COG0745	RESPONSE REGULATOR receiver
DN752_RS22550	COG3292	Two component regulator propeller
DN752_RS22550	COG2205	protein histidine kinase activity
DN752_RS22555	COG3119	arylsulfatase activity
DN752_RS22560	COG3250	beta-galactosidase activity
DN752_RS22565	COG3119	arylsulfatase activity
DN752_RS22590	COG4771	TonB-dependent receptor
DN752_RS22615	COG4771	TonB-dependent receptor
DN752_RS22620	COG0702	epimerase
DN752_RS22655	COG3119	arylsulfatase activity
DN752_RS22660	COG3119	arylsulfatase activity
DN752_RS22665	COG3119	arylsulfatase activity
DN752_RS22670	COG3119	arylsulfatase activity
DN752_RS22685	COG3119	arylsulfatase activity
DN752_RS22695	COG3119	arylsulfatase activity
DN752_RS22710	COG3119	arylsulfatase activity
DN752_RS22715	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS22725	COG3408	Glycogen debranching enzyme
DN752_RS22725	COG3119	arylsulfatase activity
DN752_RS22730	COG3119	arylsulfatase activity
DN752_RS22735	COG3119	arylsulfatase activity
DN752_RS22740	COG3119	arylsulfatase activity
DN752_RS22745	COG3119	arylsulfatase activity
DN752_RS22755	COG3119	arylsulfatase activity
DN752_RS22755	COG3408	Glycogen debranching enzyme
DN752_RS22775	COG4771	TonB-dependent receptor
DN752_RS22780	COG0702	epimerase
DN752_RS22790	COG1609	Transcriptional regulator
DN752_RS22795	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DN752_RS22800	COG0574	Belongs to the PEP-utilizing enzyme family
DN752_RS22800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DN752_RS22805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DN752_RS22820	COG4771	TonB-dependent receptor
DN752_RS22835	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN752_RS22835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DN752_RS22855	COG3119	arylsulfatase activity
DN752_RS22855	COG3408	Glycogen debranching enzyme
DN752_RS22875	COG4771	TonB-dependent receptor
DN752_RS22890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS22910	COG1629	transport
DN752_RS22915	COG0702	epimerase
DN752_RS22930	COG1609	Transcriptional regulator
DN752_RS22935	COG1940	carbohydrate kinase activity
DN752_RS22940	COG4948	Mandelate Racemase Muconate Lactonizing
DN752_RS22950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS22955	COG2814	Major facilitator Superfamily
DN752_RS22965	COG3119	arylsulfatase activity
DN752_RS22970	COG3119	arylsulfatase activity
DN752_RS23000	COG3119	arylsulfatase activity
DN752_RS23030	COG3119	arylsulfatase activity
DN752_RS23045	COG1629	transport
DN752_RS23045	COG4206	TonB-dependent receptor
DN752_RS23060	COG3119	arylsulfatase activity
DN752_RS23090	COG3119	arylsulfatase activity
DN752_RS23105	COG0579	oxidoreductase
DN752_RS23110	COG1428	Deoxynucleoside kinase
DN752_RS23115	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN752_RS23165	COG1733	regulation of RNA biosynthetic process
DN752_RS23185	COG4680	protein conserved in bacteria
DN752_RS23200	COG3177	Filamentation induced by cAMP protein fic
DN752_RS23235	COG3250	beta-galactosidase activity
DN752_RS23260	COG0523	cobalamin synthesis protein
DN752_RS23275	COG2824	Alkylphosphonate utilization operon protein PhnA
DN752_RS23295	COG0433	COG0433 Predicted ATPase
DN752_RS23300	COG2081	HI0933 family
DN752_RS23320	COG0069	glutamate synthase activity
DN752_RS23325	COG1846	Transcriptional regulator
DN752_RS23335	COG1764	response to oxidative stress
DN752_RS23345	COG3408	Glycogen debranching enzyme
DN752_RS23350	COG3408	Glycogen debranching enzyme
DN752_RS23355	COG3119	arylsulfatase activity
DN752_RS23355	COG3408	Glycogen debranching enzyme
DN752_RS23360	COG3254	rhamnose metabolic process
DN752_RS23365	COG1028	Short-chain dehydrogenase reductase Sdr
DN752_RS23365	COG3347	Dehydrogenase
DN752_RS23370	COG4952	isomerase
DN752_RS23375	COG1070	Carbohydrate kinase
DN752_RS23390	COG1472	Belongs to the glycosyl hydrolase 3 family
DN752_RS23400	COG0745	RESPONSE REGULATOR receiver
DN752_RS23400	COG3292	Two component regulator propeller
DN752_RS23400	COG2205	protein histidine kinase activity
DN752_RS23410	COG3119	arylsulfatase activity
DN752_RS23415	COG1472	Belongs to the glycosyl hydrolase 3 family
DN752_RS23420	COG3119	arylsulfatase activity
DN752_RS23430	COG4771	TonB-dependent receptor
DN752_RS23435	COG0702	epimerase
DN752_RS23445	COG1629	transport
DN752_RS23450	COG0702	epimerase
DN752_RS23470	COG4771	TonB-dependent receptor
DN752_RS23490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS23515	COG4206	TonB-dependent receptor
DN752_RS23515	COG1629	transport
DN752_RS23540	COG3119	arylsulfatase activity
DN752_RS23555	COG3119	arylsulfatase activity
DN752_RS23560	COG3250	beta-galactosidase activity
DN752_RS23565	COG3119	arylsulfatase activity
DN752_RS23565	COG3408	Glycogen debranching enzyme
DN752_RS23570	COG3119	arylsulfatase activity
DN752_RS23575	COG3119	arylsulfatase activity
DN752_RS23590	COG0745	RESPONSE REGULATOR receiver
DN752_RS23590	COG2205	protein histidine kinase activity
DN752_RS23590	COG3292	Two component regulator propeller
DN752_RS23595	COG0702	epimerase
DN752_RS23630	COG4771	TonB-dependent receptor
DN752_RS23635	COG0702	epimerase
DN752_RS23655	COG4771	TonB-dependent receptor
DN752_RS23665	COG1629	transport
DN752_RS23670	COG0702	epimerase
DN752_RS23690	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS23705	COG2382	esterase
DN752_RS23715	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS23720	COG3507	Belongs to the glycosyl hydrolase 43 family
DN752_RS23785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DN752_RS23805	COG0010	Belongs to the arginase family
DN752_RS23820	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DN752_RS23830	COG0494	nUDIX hydrolase
DN752_RS23845	COG0393	Putative heavy-metal-binding
DN752_RS23855	COG0646	methionine synthase
DN752_RS23855	COG1410	methionine synthase
DN752_RS23865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DN752_RS23870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DN752_RS23870	COG0515	serine threonine protein kinase
DN752_RS23875	COG0673	inositol 2-dehydrogenase activity
DN752_RS23880	COG0673	inositol 2-dehydrogenase activity
DN752_RS23890	COG2721	sulfolactate sulfo-lyase activity
DN752_RS23915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DN752_RS23930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DN752_RS23945	COG4771	TonB-dependent receptor
DN752_RS23950	COG0702	epimerase
DN752_RS23965	COG4771	TonB-dependent receptor
DN752_RS23985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DN752_RS23995	COG0791	NLP P60 protein
DN752_RS24005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DN752_RS24015	COG0745	RESPONSE REGULATOR receiver
DN752_RS24025	COG1215	transferase activity, transferring glycosyl groups
DN752_RS24045	COG2885	chlorophyll binding
DN752_RS24050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN752_RS24050	COG2885	chlorophyll binding
DN752_RS24055	COG4771	TonB-dependent receptor
DN752_RS24090	COG2188	Transcriptional regulator
DN752_RS24095	COG3537	Alpha-1,2-mannosidase
DN752_RS24115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DN752_RS24205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN752_RS24215	COG0513	Belongs to the DEAD box helicase family
DN752_RS24250	COG3501	Rhs element vgr protein