locus-tag	class	description
AAZ33_RS00010	COG0592	DNA-directed DNA polymerase activity
AAZ33_RS00020	COG0187	DNA topoisomerase II activity
AAZ33_RS00025	COG0561	phosphatase activity
AAZ33_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
AAZ33_RS00035	COG5645	(Lipo)protein
AAZ33_RS00050	COG3977	Valine--pyruvate aminotransferase
AAZ33_RS00055	COG3722	fumarate hydratase activity
AAZ33_RS00065	COG2213	PTS system mannitol-specific
AAZ33_RS00065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS00085	COG2818	Glycosylase
AAZ33_RS00090	COG0456	acetyltransferase
AAZ33_RS00095	COG2119	membrane
AAZ33_RS00100	COG2885	chlorophyll binding
AAZ33_RS00110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AAZ33_RS00130	COG2982	Protein involved in outer membrane biogenesis
AAZ33_RS00135	COG2233	PERMEase
AAZ33_RS00140	COG0786	glutamate:sodium symporter activity
AAZ33_RS00145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAZ33_RS00150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAZ33_RS00155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAZ33_RS00165	COG0194	GDP metabolic process
AAZ33_RS00170	COG2860	membrane
AAZ33_RS00175	COG1561	YicC-like family, N-terminal region
AAZ33_RS00195	COG0756	dUTP diphosphatase activity
AAZ33_RS00200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAZ33_RS00205	COG2003	Belongs to the UPF0758 family
AAZ33_RS00235	COG1519	Transferase
AAZ33_RS00240	COG0438	transferase activity, transferring glycosyl groups
AAZ33_RS00250	COG0859	PFAM glycosyl transferase family 9
AAZ33_RS00275	COG0859	PFAM glycosyl transferase family 9
AAZ33_RS00290	COG0156	8-amino-7-oxononanoate synthase activity
AAZ33_RS00305	COG2814	Major facilitator Superfamily
AAZ33_RS00315	COG3978	acetolactate synthase activity
AAZ33_RS00320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AAZ33_RS00345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAZ33_RS00355	COG0248	Ppx GppA phosphatase
AAZ33_RS00365	COG3118	belongs to the thioredoxin family
AAZ33_RS00375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAZ33_RS00380	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AAZ33_RS00385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AAZ33_RS00390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AAZ33_RS00395	COG1088	dTDP-glucose 4,6-dehydratase activity
AAZ33_RS00400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AAZ33_RS00405	COG0456	acetyltransferase
AAZ33_RS00415	COG2244	polysaccharide biosynthetic process
AAZ33_RS00420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAZ33_RS00455	COG3071	HemY protein
AAZ33_RS00460	COG2959	enzyme of heme biosynthesis
AAZ33_RS00495	COG3159	Protein conserved in bacteria
AAZ33_RS00505	COG1011	Hydrolase
AAZ33_RS00510	COG0210	DNA helicase
AAZ33_RS00515	COG0598	Magnesium transport protein CorA
AAZ33_RS00530	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AAZ33_RS00550	COG2610	gluconate transmembrane transporter activity
AAZ33_RS00555	COG3265	gluconokinase activity
AAZ33_RS00560	COG1609	Transcriptional regulator
AAZ33_RS00565	COG2217	Heavy metal translocating P-type atpase
AAZ33_RS00585	COG0583	DNA-binding transcription factor activity
AAZ33_RS00590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AAZ33_RS00600	COG1966	Carbon starvation protein
AAZ33_RS00605	COG0586	Pfam SNARE associated Golgi protein
AAZ33_RS00610	COG1322	Protein conserved in bacteria
AAZ33_RS00630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAZ33_RS00635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAZ33_RS00640	COG0805	protein transport
AAZ33_RS00680	COG1739	Uncharacterized protein family UPF0029
AAZ33_RS00685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AAZ33_RS00715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAZ33_RS00760	COG0250	Participates in transcription elongation, termination and antitermination
AAZ33_RS00780	COG0222	ribosome binding
AAZ33_RS00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAZ33_RS00810	COG1515	deoxyribonuclease V activity
AAZ33_RS00830	COG0151	Belongs to the GarS family
AAZ33_RS00880	COG1584	GPR1 FUN34 yaaH family protein
AAZ33_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AAZ33_RS00890	COG1301	dicarboxylic acid transport
AAZ33_RS00895	COG1538	Outer membrane efflux protein
AAZ33_RS00900	COG0494	nUDIX hydrolase
AAZ33_RS00905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AAZ33_RS00910	COG3150	esterase
AAZ33_RS00915	COG0187	DNA topoisomerase II activity
AAZ33_RS00920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAZ33_RS00945	COG0527	aspartate kinase activity
AAZ33_RS00965	COG3833	ABC-type maltose transport systems, permease component
AAZ33_RS00970	COG1175	transmembrane transport
AAZ33_RS00975	COG2182	Extracellular solute-binding protein
AAZ33_RS00995	COG3161	chorismate lyase activity
AAZ33_RS01015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AAZ33_RS01020	COG0471	metal ion transport
AAZ33_RS01035	COG3051	citrate lyase alpha subunit
AAZ33_RS01040	COG2301	Belongs to the HpcH HpaI aldolase family
AAZ33_RS01050	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AAZ33_RS01055	COG3290	protein histidine kinase activity
AAZ33_RS01060	COG4565	transcriptional regulatory protein
AAZ33_RS01080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAZ33_RS01100	COG1979	alcohol dehydrogenase
AAZ33_RS01105	COG2207	Transcriptional regulator
AAZ33_RS01125	COG2181	nitrate reductase activity
AAZ33_RS01130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AAZ33_RS01135	COG1140	nitrate reductase beta subunit
AAZ33_RS01140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AAZ33_RS01145	COG2223	nitrite transmembrane transporter activity
AAZ33_RS01150	COG0471	metal ion transport
AAZ33_RS01160	COG1982	Orn Lys Arg decarboxylase major
AAZ33_RS01165	COG0531	amino acid
AAZ33_RS01185	COG1194	a g-specific adenine glycosylase
AAZ33_RS01195	COG3171	Protein conserved in bacteria
AAZ33_RS01200	COG2066	Belongs to the glutaminase family
AAZ33_RS01210	COG4166	transmembrane transport
AAZ33_RS01215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAZ33_RS01230	COG0762	integral membrane protein
AAZ33_RS01235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AAZ33_RS01245	COG1678	Uncharacterized ACR, COG1678
AAZ33_RS01250	COG0189	ligase activity
AAZ33_RS01255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAZ33_RS01260	COG2356	endonuclease I
AAZ33_RS01265	COG3091	SprT-like family
AAZ33_RS01270	COG0531	amino acid
AAZ33_RS01280	COG0754	glutathionylspermidine amidase activity
AAZ33_RS01290	COG1349	DNA-binding transcription factor activity
AAZ33_RS01310	COG0738	Major facilitator superfamily
AAZ33_RS01315	COG0235	Class ii aldolase
AAZ33_RS01325	COG3247	response to pH
AAZ33_RS01330	COG3781	membrane
AAZ33_RS01340	COG0243	molybdopterin cofactor binding
AAZ33_RS01345	COG3005	denitrification pathway
AAZ33_RS01350	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS01355	COG1879	ABC-type sugar transport system periplasmic component
AAZ33_RS01360	COG0784	Response regulator, receiver
AAZ33_RS01360	COG2198	Histidine kinase
AAZ33_RS01360	COG2205	protein histidine kinase activity
AAZ33_RS01375	COG2084	Dehydrogenase
AAZ33_RS01400	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAZ33_RS01405	COG1609	Transcriptional regulator
AAZ33_RS01420	COG1309	transcriptional regulator
AAZ33_RS01425	COG4232	protein-disulfide reductase activity
AAZ33_RS01435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AAZ33_RS01445	COG3030	protein affecting phage T7 exclusion by the F plasmid
AAZ33_RS01475	COG1556	Lactate utilization protein
AAZ33_RS01480	COG1139	Iron-sulfur cluster binding protein
AAZ33_RS01485	COG0247	lactate metabolic process
AAZ33_RS01515	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AAZ33_RS01520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AAZ33_RS01525	COG1053	succinate dehydrogenase
AAZ33_RS01535	COG1511	domain protein
AAZ33_RS01535	COG3264	Mechanosensitive ion channel
AAZ33_RS01540	COG0688	phosphatidylethanolamine metabolic process
AAZ33_RS01545	COG1162	GTPase activity
AAZ33_RS01550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AAZ33_RS01580	COG0802	atpase or kinase
AAZ33_RS01595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAZ33_RS01605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAZ33_RS01610	COG0330	HflC and HflK could
AAZ33_RS01615	COG0330	HflC and HflK could
AAZ33_RS01625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AAZ33_RS01635	COG1959	2 iron, 2 sulfur cluster binding
AAZ33_RS01640	COG0557	exoribonuclease II activity
AAZ33_RS01645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAZ33_RS01655	COG3650	response to hydrogen peroxide
AAZ33_RS01660	COG1073	alpha beta
AAZ33_RS01680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAZ33_RS01695	COG3061	Opacity-associated protein A
AAZ33_RS01700	COG0545	Peptidyl-prolyl cis-trans isomerase
AAZ33_RS01720	COG1253	flavin adenine dinucleotide binding
AAZ33_RS01730	COG0729	surface antigen
AAZ33_RS01740	COG2105	PFAM AIG2 family protein
AAZ33_RS01745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AAZ33_RS01750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AAZ33_RS01755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAZ33_RS01775	COG3423	Transcriptional regulator
AAZ33_RS01780	COG0142	geranyltranstransferase activity
AAZ33_RS01785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AAZ33_RS01795	COG0697	spore germination
AAZ33_RS01800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAZ33_RS01805	COG0642	Histidine kinase
AAZ33_RS01810	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS01815	COG2027	D-alanyl-D-alanine carboxypeptidase
AAZ33_RS01825	COG1534	Rna-binding protein
AAZ33_RS01840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AAZ33_RS01850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AAZ33_RS01870	COG0195	Participates in both transcription termination and antitermination
AAZ33_RS01905	COG0513	Belongs to the DEAD box helicase family
AAZ33_RS01910	COG0814	amino acid
AAZ33_RS01920	COG0826	peptidase U32
AAZ33_RS01925	COG0826	peptidase U32
AAZ33_RS01930	COG3154	lipid carrier protein
AAZ33_RS01935	COG3153	acetyltransferase
AAZ33_RS01940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAZ33_RS01945	COG2827	Endonuclease containing a URI domain
AAZ33_RS01950	COG3787	Belongs to the UPF0306 family
AAZ33_RS01955	COG0702	epimerase
AAZ33_RS01960	COG0602	queuosine metabolic process
AAZ33_RS01975	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AAZ33_RS01980	COG4575	ribosome binding
AAZ33_RS01990	COG0586	Pfam SNARE associated Golgi protein
AAZ33_RS02000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAZ33_RS02010	COG2271	Major facilitator Superfamily
AAZ33_RS02020	COG0246	Mannitol dehydrogenase
AAZ33_RS02025	COG2721	sulfolactate sulfo-lyase activity
AAZ33_RS02040	COG0861	Integral membrane protein TerC family
AAZ33_RS02045	COG0697	spore germination
AAZ33_RS02050	COG0673	inositol 2-dehydrogenase activity
AAZ33_RS02055	COG1451	nucleotide metabolic process
AAZ33_RS02060	COG2813	Specifically methylates the guanine in position
AAZ33_RS02065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAZ33_RS02070	COG0642	Histidine kinase
AAZ33_RS02080	COG3111	PFAM Bacterial OB fold (BOF) protein
AAZ33_RS02085	COG1882	Formate acetyltransferase
AAZ33_RS02090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAZ33_RS02095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAZ33_RS02105	COG3663	DNA glycosylase
AAZ33_RS02115	COG0358	DNA primase activity
AAZ33_RS02135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAZ33_RS02150	COG4991	sh3 domain protein
AAZ33_RS02155	COG0306	phosphate transporter
AAZ33_RS02160	COG1392	Phosphate transport regulator
AAZ33_RS02165	COG3025	triphosphatase activity
AAZ33_RS02170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AAZ33_RS02175	COG1560	Kdo2-lipid A biosynthetic process
AAZ33_RS02185	COG0531	amino acid
AAZ33_RS02205	COG3384	dioxygenase
AAZ33_RS02225	COG2813	Specifically methylates the guanine in position
AAZ33_RS02230	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AAZ33_RS02235	COG0456	acetyltransferase
AAZ33_RS02245	COG4667	esterase of the alpha-beta hydrolase superfamily
AAZ33_RS02250	COG0084	hydrolase, TatD family'
AAZ33_RS02255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AAZ33_RS02260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAZ33_RS02265	COG1328	CTP reductase activity
AAZ33_RS02295	COG3783	Cytochrome b(562)
AAZ33_RS02305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAZ33_RS02310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS02330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AAZ33_RS02335	COG1137	ATPase activity
AAZ33_RS02340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AAZ33_RS02345	COG3117	lipopolysaccharide transmembrane transporter activity
AAZ33_RS02350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AAZ33_RS02355	COG0517	IMP dehydrogenase activity
AAZ33_RS02355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AAZ33_RS02360	COG0530	calcium, potassium:sodium antiporter activity
AAZ33_RS02365	COG1127	ABC transporter
AAZ33_RS02370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AAZ33_RS02375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AAZ33_RS02380	COG2854	intermembrane phospholipid transfer
AAZ33_RS02385	COG3113	response to antibiotic
AAZ33_RS02390	COG5007	Belongs to the BolA IbaG family
AAZ33_RS02395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAZ33_RS02400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAZ33_RS02405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAZ33_RS02410	COG3105	Protein conserved in bacteria
AAZ33_RS02415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AAZ33_RS02430	COG0625	glutathione transferase activity
AAZ33_RS02435	COG2969	positive regulation of protein catabolic process
AAZ33_RS02440	COG2731	YhcH YjgK YiaL family protein
AAZ33_RS02460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AAZ33_RS02475	COG0493	'glutamate synthase
AAZ33_RS02485	COG1242	4 iron, 4 sulfur cluster binding
AAZ33_RS02490	COG5002	protein histidine kinase activity
AAZ33_RS02490	COG0784	Response regulator, receiver
AAZ33_RS02490	COG2198	Histidine kinase
AAZ33_RS02500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AAZ33_RS02505	COG2823	Periplasmic or secreted lipoprotein
AAZ33_RS02515	COG0792	nuclease activity
AAZ33_RS02525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAZ33_RS02530	COG3726	membrane protein affecting hemolysin expression
AAZ33_RS02535	COG0560	Phosphoserine phosphatase
AAZ33_RS02540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AAZ33_RS02545	COG0488	(ABC) transporter
AAZ33_RS02550	COG0741	lytic transglycosylase activity
AAZ33_RS02555	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AAZ33_RS02565	COG0406	alpha-ribazole phosphatase activity
AAZ33_RS02570	COG2207	Transcriptional regulator
AAZ33_RS02570	COG3708	Transcriptional regulator
AAZ33_RS02575	COG3045	CreA protein
AAZ33_RS02585	COG1720	tRNA m6t6A37 methyltransferase activity
AAZ33_RS02595	COG1464	Belongs to the NlpA lipoprotein family
AAZ33_RS02610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AAZ33_RS02640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAZ33_RS02645	COG1042	CoA-binding domain protein
AAZ33_RS02645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAZ33_RS02645	COG0045	succinate-CoA ligase (ADP-forming) activity
AAZ33_RS02650	COG3148	PFAM DTW domain containing protein
AAZ33_RS02655	COG3118	belongs to the thioredoxin family
AAZ33_RS02665	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS02670	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AAZ33_RS02695	COG1115	amino acid carrier protein
AAZ33_RS02705	COG1012	belongs to the aldehyde dehydrogenase family
AAZ33_RS02715	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAZ33_RS02725	COG1584	GPR1 FUN34 yaaH family protein
AAZ33_RS02745	COG0583	DNA-binding transcription factor activity
AAZ33_RS02750	COG0268	Binds directly to 16S ribosomal RNA
AAZ33_RS02755	COG0196	riboflavin kinase activity
AAZ33_RS02770	COG1047	Peptidyl-prolyl cis-trans
AAZ33_RS02780	COG1881	PFAM PEBP family protein
AAZ33_RS02785	COG2080	2 iron, 2 sulfur cluster binding
AAZ33_RS02790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AAZ33_RS02805	COG0505	Belongs to the CarA family
AAZ33_RS02810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AAZ33_RS02815	COG2966	Psort location CytoplasmicMembrane, score
AAZ33_RS02825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AAZ33_RS02840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAZ33_RS02845	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AAZ33_RS02860	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AAZ33_RS02865	COG0564	pseudouridine synthase activity
AAZ33_RS02870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AAZ33_RS02880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AAZ33_RS02885	COG1178	ABC-type Fe3 transport system permease component
AAZ33_RS02890	COG4143	(ABC) transporter
AAZ33_RS02905	COG1132	(ABC) transporter
AAZ33_RS02910	COG1120	ATPase activity
AAZ33_RS02940	COG0473	3-isopropylmalate dehydrogenase activity
AAZ33_RS02955	COG1022	Amp-dependent synthetase and ligase
AAZ33_RS02960	COG0028	Belongs to the TPP enzyme family
AAZ33_RS02985	COG3116	cell division
AAZ33_RS02990	COG0768	penicillin binding
AAZ33_RS02995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAZ33_RS03000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAZ33_RS03010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAZ33_RS03015	COG0772	Belongs to the SEDS family
AAZ33_RS03035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAZ33_RS03040	COG0849	cell division
AAZ33_RS03045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AAZ33_RS03070	COG0494	nUDIX hydrolase
AAZ33_RS03095	COG1459	type II secretion system
AAZ33_RS03100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAZ33_RS03105	COG4969	Belongs to the N-Me-Phe pilin family
AAZ33_RS03110	COG3023	N-Acetylmuramoyl-L-alanine amidase
AAZ33_RS03115	COG3725	Membrane protein required for beta-lactamase induction
AAZ33_RS03120	COG1113	amino acid transport
AAZ33_RS03125	COG2186	Transcriptional regulator
AAZ33_RS03130	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AAZ33_RS03135	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAZ33_RS03140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAZ33_RS03155	COG2979	Protein of unknown function (DUF533)
AAZ33_RS03180	COG0288	reversible hydration of carbon dioxide
AAZ33_RS03185	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS03190	COG1131	(ABC) transporter
AAZ33_RS03195	COG0842	Transport permease protein
AAZ33_RS03200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS03205	COG1349	DNA-binding transcription factor activity
AAZ33_RS03215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAZ33_RS03220	COG3715	PTS system
AAZ33_RS03225	COG3716	PTS system mannose fructose sorbose family IID component
AAZ33_RS03235	COG0726	polysaccharide deacetylase
AAZ33_RS03260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAZ33_RS03285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AAZ33_RS03295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AAZ33_RS03300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AAZ33_RS03305	COG3416	Protein conserved in bacteria
AAZ33_RS03310	COG2234	aminopeptidase activity
AAZ33_RS03320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAZ33_RS03330	COG4970	Tfp pilus assembly protein FimT
AAZ33_RS03335	COG4795	General secretion pathway protein
AAZ33_RS03350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AAZ33_RS03375	COG0860	N-Acetylmuramoyl-L-alanine amidase
AAZ33_RS03395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AAZ33_RS03400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AAZ33_RS03405	COG2166	iron-sulfur cluster assembly
AAZ33_RS03410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAZ33_RS03415	COG0583	DNA-binding transcription factor activity
AAZ33_RS03420	COG2363	Small membrane protein
AAZ33_RS03435	COG1611	Belongs to the LOG family
AAZ33_RS03475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AAZ33_RS03485	COG0052	Belongs to the universal ribosomal protein uS2 family
AAZ33_RS03495	COG0528	UMP kinase activity
AAZ33_RS03515	COG0575	Belongs to the CDS family
AAZ33_RS03520	COG0750	zinc metalloprotease
AAZ33_RS03530	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AAZ33_RS03535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAZ33_RS03540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAZ33_RS03545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAZ33_RS03560	COG0587	DNA-directed DNA polymerase activity
AAZ33_RS03570	COG0346	lactoylglutathione lyase activity
AAZ33_RS03580	COG0531	amino acid
AAZ33_RS03585	COG1982	Orn Lys Arg decarboxylase major
AAZ33_RS03605	COG4568	rho-dependent transcription termination
AAZ33_RS03615	COG4681	YaeQ
AAZ33_RS03625	COG3015	lipoprotein NlpE involved in copper resistance
AAZ33_RS03630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS03635	COG1737	Transcriptional regulator
AAZ33_RS03640	COG0560	Phosphoserine phosphatase
AAZ33_RS03645	COG1454	alcohol dehydrogenase
AAZ33_RS03650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAZ33_RS03660	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AAZ33_RS03680	COG2204	response regulator
AAZ33_RS03690	COG0347	Belongs to the P(II) protein family
AAZ33_RS03700	COG0121	glutamine amidotransferase
AAZ33_RS03705	COG3034	peptidoglycan biosynthetic process
AAZ33_RS03710	COG1477	protein flavinylation
AAZ33_RS03715	COG0531	amino acid
AAZ33_RS03720	COG0531	amino acid
AAZ33_RS03735	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAZ33_RS03750	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAZ33_RS03760	COG1073	alpha beta
AAZ33_RS03770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAZ33_RS03780	COG2130	NADP-dependent
AAZ33_RS03790	COG0582	viral genome integration into host DNA
AAZ33_RS03815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAZ33_RS03855	COG0305	Participates in initiation and elongation during chromosome replication
AAZ33_RS03905	COG3179	chitinase
AAZ33_RS03925	COG1783	phage Terminase large subunit
AAZ33_RS04145	COG1857	crispr-associated protein
AAZ33_RS04155	COG1518	maintenance of DNA repeat elements
AAZ33_RS04190	COG1388	LysM domain
AAZ33_RS04190	COG3942	CHAP domain
AAZ33_RS04200	COG1475	DNA binding
AAZ33_RS04235	COG1470	cell adhesion involved in biofilm formation
AAZ33_RS04235	COG1388	LysM domain
AAZ33_RS04275	COG2149	membrane
AAZ33_RS04290	COG2211	Major facilitator Superfamily
AAZ33_RS04295	COG0641	radical SAM
AAZ33_RS04320	COG3210	domain, Protein
AAZ33_RS04370	COG2831	hemolysin activation secretion protein
AAZ33_RS04380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAZ33_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS04420	COG1216	Glycosyl transferase, family 2
AAZ33_RS04440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAZ33_RS04470	COG0814	amino acid
AAZ33_RS04480	COG0583	DNA-binding transcription factor activity
AAZ33_RS04485	COG2610	gluconate transmembrane transporter activity
AAZ33_RS04505	COG3842	ATPase activity
AAZ33_RS04515	COG2188	Transcriptional regulator
AAZ33_RS04535	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AAZ33_RS04540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AAZ33_RS04550	COG0402	S-adenosylhomocysteine deaminase activity
AAZ33_RS04590	COG4977	sequence-specific DNA binding
AAZ33_RS04715	COG2197	response regulator
AAZ33_RS04730	COG0583	DNA-binding transcription factor activity
AAZ33_RS04735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAZ33_RS04765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAZ33_RS04770	COG2104	thiamine diphosphate biosynthetic process
AAZ33_RS04810	COG1175	transmembrane transport
AAZ33_RS04815	COG1653	transport
AAZ33_RS04840	COG1275	C4-dicarboxylate transporter malic acid transport protein
AAZ33_RS04850	COG1882	Formate acetyltransferase
AAZ33_RS04865	COG0778	Nitroreductase
AAZ33_RS04880	COG0583	DNA-binding transcription factor activity
AAZ33_RS04885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AAZ33_RS04900	COG0725	ABC transporter, periplasmic molybdate-binding protein
AAZ33_RS04910	COG3842	ATPase activity
AAZ33_RS04925	COG1737	Transcriptional regulator
AAZ33_RS04930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAZ33_RS04950	COG1566	PFAM secretion protein HlyD family protein
AAZ33_RS04965	COG1011	Hydrolase
AAZ33_RS04985	COG0531	amino acid
AAZ33_RS04990	COG0443	Heat shock 70 kDa protein
AAZ33_RS04995	COG5001	Diguanylate cyclase
AAZ33_RS04995	COG5002	protein histidine kinase activity
AAZ33_RS04995	COG3447	MASE1 domain protein
AAZ33_RS05030	COG0668	transmembrane transport
AAZ33_RS05040	COG0450	alkyl hydroperoxide reductase
AAZ33_RS05045	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AAZ33_RS05060	COG1862	Preprotein translocase
AAZ33_RS05065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAZ33_RS05070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAZ33_RS05080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAZ33_RS05080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAZ33_RS05100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AAZ33_RS05110	COG0142	geranyltranstransferase activity
AAZ33_RS05125	COG1122	ATPase activity
AAZ33_RS05150	COG0693	protein deglycase activity
AAZ33_RS05155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AAZ33_RS05165	COG0788	formyltetrahydrofolate deformylase activity
AAZ33_RS05185	COG0693	protein deglycase activity
AAZ33_RS05195	COG2814	Major facilitator Superfamily
AAZ33_RS05200	COG2223	nitrite transmembrane transporter activity
AAZ33_RS05205	COG3056	Lipoprotein
AAZ33_RS05210	COG0271	Belongs to the BolA IbaG family
AAZ33_RS05230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAZ33_RS05240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAZ33_RS05255	COG4533	DNA binding
AAZ33_RS05260	COG0561	phosphatase activity
AAZ33_RS05265	COG1522	sequence-specific DNA binding
AAZ33_RS05270	COG0347	Belongs to the P(II) protein family
AAZ33_RS05275	COG0004	ammonium transporteR
AAZ33_RS05280	COG1946	Acyl-CoA thioesterase
AAZ33_RS05285	COG3695	enzyme binding
AAZ33_RS05300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAZ33_RS05305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAZ33_RS05310	COG1309	transcriptional regulator
AAZ33_RS05315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AAZ33_RS05320	COG3264	Mechanosensitive ion channel
AAZ33_RS05320	COG1196	nuclear chromosome segregation
AAZ33_RS05330	COG2261	transglycosylase associated protein
AAZ33_RS05340	COG2832	Protein of unknown function (DUF454)
AAZ33_RS05380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAZ33_RS05390	COG3121	Chaperone
AAZ33_RS05395	COG3188	usher protein
AAZ33_RS05400	COG3539	Fimbrial protein
AAZ33_RS05405	COG0737	Belongs to the 5'-nucleotidase family
AAZ33_RS05415	COG2610	gluconate transmembrane transporter activity
AAZ33_RS05420	COG2186	Transcriptional regulator
AAZ33_RS05425	COG3735	TraB family
AAZ33_RS05440	COG1585	Membrane protein implicated in regulation of membrane protease activity
AAZ33_RS05445	COG0330	HflC and HflK could
AAZ33_RS05455	COG0602	queuosine metabolic process
AAZ33_RS05460	COG2814	Major facilitator Superfamily
AAZ33_RS05465	COG0720	synthase
AAZ33_RS05470	COG0277	FAD linked oxidase domain protein
AAZ33_RS05475	COG0640	Transcriptional regulator
AAZ33_RS05490	COG2351	hydroxyisourate hydrolase activity
AAZ33_RS05495	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AAZ33_RS05500	COG0351	phosphomethylpyrimidine kinase
AAZ33_RS05515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAZ33_RS05520	COG0583	DNA-binding transcription factor activity
AAZ33_RS05525	COG0826	peptidase U32
AAZ33_RS05530	COG3422	double-strand break repair
AAZ33_RS05535	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS05540	COG2205	protein histidine kinase activity
AAZ33_RS05595	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS05600	COG5002	protein histidine kinase activity
AAZ33_RS05610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AAZ33_RS05615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAZ33_RS05620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAZ33_RS05645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAZ33_RS05655	COG4783	chaperone-mediated protein folding
AAZ33_RS05660	COG0628	permease
AAZ33_RS05665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAZ33_RS05670	COG2716	regulation of RNA biosynthetic process
AAZ33_RS05680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AAZ33_RS05700	COG0400	carboxylic ester hydrolase activity
AAZ33_RS05715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAZ33_RS05720	COG1393	Belongs to the ArsC family
AAZ33_RS05730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAZ33_RS05740	COG2197	response regulator
AAZ33_RS05745	COG3850	Histidine kinase
AAZ33_RS05755	COG3062	negative regulation of establishment of protein localization
AAZ33_RS05765	COG0437	4 iron, 4 sulfur cluster binding
AAZ33_RS05770	COG0348	domain, Protein
AAZ33_RS05775	COG3043	anaerobic respiration
AAZ33_RS05780	COG3005	denitrification pathway
AAZ33_RS05785	COG0698	ribose 5-phosphate isomerase
AAZ33_RS05790	COG1063	alcohol dehydrogenase
AAZ33_RS05795	COG2814	Major facilitator Superfamily
AAZ33_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS05805	COG2376	Dihydroxyacetone kinase
AAZ33_RS05810	COG1461	Dihydroxyacetone kinase
AAZ33_RS05815	COG2390	Transcriptional regulator
AAZ33_RS05820	COG0494	nUDIX hydrolase
AAZ33_RS05835	COG1671	Belongs to the UPF0178 family
AAZ33_RS05845	COG0860	N-Acetylmuramoyl-L-alanine amidase
AAZ33_RS05850	COG0456	acetyltransferase
AAZ33_RS05860	COG2837	iron assimilation
AAZ33_RS05865	COG2190	(PTS) system
AAZ33_RS05875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS05935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAZ33_RS05965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AAZ33_RS05970	COG1914	H( )-stimulated, divalent metal cation uptake system
AAZ33_RS05995	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AAZ33_RS06000	COG2943	transferase activity, transferring hexosyl groups
AAZ33_RS06005	COG1609	Transcriptional regulator
AAZ33_RS06020	COG0303	'Molybdopterin
AAZ33_RS06030	COG2311	Membrane
AAZ33_RS06040	COG2949	membrane
AAZ33_RS06055	COG1346	cytolysis
AAZ33_RS06060	COG1380	Effector of murein hydrolase LrgA
AAZ33_RS06065	COG2962	Rard protein
AAZ33_RS06070	COG2925	Exonuclease
AAZ33_RS06080	COG1289	transmembrane transporter activity
AAZ33_RS06090	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AAZ33_RS06105	COG2855	membrane
AAZ33_RS06120	COG0583	DNA-binding transcription factor activity
AAZ33_RS06125	COG0833	amino acid
AAZ33_RS06130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAZ33_RS06130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAZ33_RS06140	COG0572	uridine kinase
AAZ33_RS06145	COG0697	spore germination
AAZ33_RS06160	COG3069	C4-dicarboxylate transmembrane transporter activity
AAZ33_RS06165	COG2244	polysaccharide biosynthetic process
AAZ33_RS06170	COG0438	transferase activity, transferring glycosyl groups
AAZ33_RS06185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AAZ33_RS06205	COG2089	acid synthase
AAZ33_RS06220	COG2244	polysaccharide biosynthetic process
AAZ33_RS06255	COG0626	cystathionine gamma-synthase activity
AAZ33_RS06260	COG0814	amino acid
AAZ33_RS06265	COG0583	DNA-binding transcription factor activity
AAZ33_RS06280	COG2194	sulfuric ester hydrolase activity
AAZ33_RS06285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAZ33_RS06290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAZ33_RS06300	COG3418	PFAM FlgN family protein
AAZ33_RS06305	COG2747	anti-sigma28 factor FlgM
AAZ33_RS06315	COG1815	bacterial-type flagellum-dependent cell motility
AAZ33_RS06320	COG1558	bacterial-type flagellum-dependent cell motility
AAZ33_RS06330	COG1749	Flagellar hook protein flgE
AAZ33_RS06340	COG4786	Flagellar basal body rod
AAZ33_RS06345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AAZ33_RS06370	COG3059	membrane
AAZ33_RS06380	COG1448	Aminotransferase
AAZ33_RS06400	COG0308	aminopeptidase N
AAZ33_RS06420	COG3959	Transketolase, thiamine diphosphate binding domain
AAZ33_RS06425	COG3958	Transketolase
AAZ33_RS06430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAZ33_RS06440	COG3069	C4-dicarboxylate transmembrane transporter activity
AAZ33_RS06490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AAZ33_RS06490	COG0116	Belongs to the methyltransferase superfamily
AAZ33_RS06495	COG0488	(ABC) transporter
AAZ33_RS06500	COG2995	paraquat-inducible protein a
AAZ33_RS06505	COG3008	intermembrane lipid transfer
AAZ33_RS06505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AAZ33_RS06510	COG3009	Protein conserved in bacteria
AAZ33_RS06520	COG1067	ATP-dependent peptidase activity
AAZ33_RS06525	COG3120	sequence-specific DNA binding
AAZ33_RS06540	COG3070	regulator of competence-specific genes
AAZ33_RS06545	COG1289	transmembrane transporter activity
AAZ33_RS06550	COG3304	Inner membrane component domain
AAZ33_RS06555	COG0210	DNA helicase
AAZ33_RS06585	COG1254	Belongs to the acylphosphatase family
AAZ33_RS06590	COG2920	part of a sulfur-relay system
AAZ33_RS06595	COG0670	Belongs to the BI1 family
AAZ33_RS06625	COG1280	lysine exporter protein (LysE YggA)
AAZ33_RS06630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAZ33_RS06635	COG1960	acyl-CoA dehydrogenase activity
AAZ33_RS06640	COG1846	Transcriptional regulator
AAZ33_RS06645	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAZ33_RS06655	COG1012	belongs to the aldehyde dehydrogenase family
AAZ33_RS06660	COG3384	dioxygenase
AAZ33_RS06670	COG2814	Major facilitator Superfamily
AAZ33_RS06680	COG3971	2-oxopent-4-enoate hydratase activity
AAZ33_RS06700	COG2271	Major facilitator Superfamily
AAZ33_RS06705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAZ33_RS06725	COG0726	polysaccharide deacetylase
AAZ33_RS06735	COG2076	Multidrug Resistance protein
AAZ33_RS06740	COG2076	Multidrug Resistance protein
AAZ33_RS06760	COG1278	Cold shock
AAZ33_RS06860	COG2207	Transcriptional regulator
AAZ33_RS06865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAZ33_RS06870	COG1335	isochorismatase
AAZ33_RS06875	COG2194	sulfuric ester hydrolase activity
AAZ33_RS06880	COG0768	penicillin binding
AAZ33_RS06895	COG1979	alcohol dehydrogenase
AAZ33_RS06925	COG0835	chemotaxis
AAZ33_RS06930	COG0840	transmembrane signaling receptor activity
AAZ33_RS06935	COG0840	transmembrane signaling receptor activity
AAZ33_RS06940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AAZ33_RS06950	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS06955	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AAZ33_RS06965	COG0387	Pfam Sodium calcium exchanger
AAZ33_RS06970	COG0586	Pfam SNARE associated Golgi protein
AAZ33_RS06975	COG5645	(Lipo)protein
AAZ33_RS06980	COG1473	amidohydrolase
AAZ33_RS06985	COG3069	C4-dicarboxylate transmembrane transporter activity
AAZ33_RS06990	COG0583	DNA-binding transcription factor activity
AAZ33_RS07005	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAZ33_RS07010	COG3493	citrate carrier protein
AAZ33_RS07015	COG3069	C4-dicarboxylate transmembrane transporter activity
AAZ33_RS07020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAZ33_RS07025	COG0583	DNA-binding transcription factor activity
AAZ33_RS07045	COG3122	Protein conserved in bacteria
AAZ33_RS07050	COG0513	Belongs to the DEAD box helicase family
AAZ33_RS07060	COG2249	NAD(P)H dehydrogenase (quinone) activity
AAZ33_RS07065	COG1902	pentaerythritol trinitrate reductase activity
AAZ33_RS07080	COG0583	DNA-binding transcription factor activity
AAZ33_RS07085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAZ33_RS07095	COG0549	Belongs to the carbamate kinase family
AAZ33_RS07100	COG1304	FMN binding
AAZ33_RS07130	COG1132	(ABC) transporter
AAZ33_RS07150	COG0444	Belongs to the ABC transporter superfamily
AAZ33_RS07155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAZ33_RS07160	COG0601	transmembrane transport
AAZ33_RS07165	COG0747	negative chemotaxis
AAZ33_RS07200	COG1231	oxidoreductase activity
AAZ33_RS07205	COG2149	membrane
AAZ33_RS07210	COG3119	arylsulfatase activity
AAZ33_RS07215	COG2271	Major facilitator Superfamily
AAZ33_RS07230	COG0012	GTP binding
AAZ33_RS07250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAZ33_RS07260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AAZ33_RS07275	COG2890	protein-(glutamine-N5) methyltransferase activity
AAZ33_RS07290	COG0659	secondary active sulfate transmembrane transporter activity
AAZ33_RS07305	COG2160	L-arabinose isomerase activity
AAZ33_RS07315	COG1069	ribulokinase activity
AAZ33_RS07320	COG1879	ABC-type sugar transport system periplasmic component
AAZ33_RS07330	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAZ33_RS07350	COG4134	Bacterial extracellular solute-binding protein
AAZ33_RS07360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAZ33_RS07375	COG3381	protein complex oligomerization
AAZ33_RS07390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAZ33_RS07400	COG0728	peptidoglycan biosynthetic process
AAZ33_RS07410	COG3102	Protein conserved in bacteria
AAZ33_RS07415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AAZ33_RS07435	COG1113	amino acid transport
AAZ33_RS07440	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AAZ33_RS07445	COG1801	Protein of unknown function DUF72
AAZ33_RS07455	COG0494	nUDIX hydrolase
AAZ33_RS07480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAZ33_RS07485	COG1121	(ABC) transporter
AAZ33_RS07490	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AAZ33_RS07495	COG0739	heme binding
AAZ33_RS07500	COG1560	Kdo2-lipid A biosynthetic process
AAZ33_RS07505	COG0730	response to heat
AAZ33_RS07510	COG0469	pyruvate kinase activity
AAZ33_RS07515	COG1737	Transcriptional regulator
AAZ33_RS07520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AAZ33_RS07525	COG0363	glucosamine-6-phosphate deaminase activity
AAZ33_RS07530	COG0129	dihydroxy-acid dehydratase activity
AAZ33_RS07535	COG0800	Aldolase
AAZ33_RS07540	COG2076	Multidrug Resistance protein
AAZ33_RS07550	COG0251	oxidation-reduction process
AAZ33_RS07555	COG1199	ATP-dependent helicase activity
AAZ33_RS07565	COG3065	identical protein binding
AAZ33_RS07570	COG0318	PFAM AMP-dependent synthetase and ligase
AAZ33_RS07585	COG2894	cell division
AAZ33_RS07595	COG3100	YcgL domain-containing protein
AAZ33_RS07600	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAZ33_RS07635	COG2719	SpoVR family
AAZ33_RS07670	COG2766	serine protein kinase
AAZ33_RS07675	COG3713	MltA-interacting MipA family protein
AAZ33_RS07690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AAZ33_RS07695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAZ33_RS07700	COG3139	Protein of unknown function (DUF1315)
AAZ33_RS07705	COG1335	isochorismatase
AAZ33_RS07710	COG0252	asparaginase activity
AAZ33_RS07715	COG0616	signal peptide processing
AAZ33_RS07720	COG0778	Nitroreductase
AAZ33_RS07730	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AAZ33_RS07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAZ33_RS07745	COG0494	nUDIX hydrolase
AAZ33_RS07750	COG0708	Exodeoxyribonuclease III
AAZ33_RS07770	COG0788	formyltetrahydrofolate deformylase activity
AAZ33_RS07775	COG3012	SEC-C Motif Domain Protein
AAZ33_RS07780	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS07785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AAZ33_RS07800	COG1012	belongs to the aldehyde dehydrogenase family
AAZ33_RS07800	COG1454	alcohol dehydrogenase
AAZ33_RS07805	COG2095	MarC family integral membrane protein
AAZ33_RS07815	COG0601	transmembrane transport
AAZ33_RS07820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAZ33_RS07845	COG0783	Belongs to the Dps family
AAZ33_RS07850	COG2350	Protein conserved in bacteria
AAZ33_RS07860	COG1607	acyl-coa hydrolase
AAZ33_RS07885	COG3047	cAMP biosynthetic process
AAZ33_RS07905	COG0134	indole-3-glycerol-phosphate synthase activity
AAZ33_RS07905	COG0135	phosphoribosylanthranilate isomerase activity
AAZ33_RS07925	COG0613	PHP domain protein
AAZ33_RS07930	COG0009	L-threonylcarbamoyladenylate synthase
AAZ33_RS07940	COG0765	amino acid transport
AAZ33_RS07945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAZ33_RS07950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AAZ33_RS07955	COG2207	Transcriptional regulator
AAZ33_RS07970	COG1187	pseudouridine synthase activity
AAZ33_RS07980	COG0406	alpha-ribazole phosphatase activity
AAZ33_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS07995	COG0616	signal peptide processing
AAZ33_RS08010	COG0583	DNA-binding transcription factor activity
AAZ33_RS08020	COG2226	methyltransferase
AAZ33_RS08030	COG3716	PTS system mannose fructose sorbose family IID component
AAZ33_RS08035	COG3715	PTS system
AAZ33_RS08040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS08040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAZ33_RS08045	COG1253	flavin adenine dinucleotide binding
AAZ33_RS08050	COG2200	EAL domain
AAZ33_RS08080	COG0307	riboflavin synthase, alpha
AAZ33_RS08085	COG2814	Major facilitator Superfamily
AAZ33_RS08090	COG1414	Transcriptional regulator
AAZ33_RS08095	COG1823	symporter activity
AAZ33_RS08100	COG1988	membrane-bound metal-dependent
AAZ33_RS08105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAZ33_RS08115	COG3001	Fructosamine kinase
AAZ33_RS08130	COG0814	amino acid
AAZ33_RS08145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAZ33_RS08150	COG0601	transmembrane transport
AAZ33_RS08155	COG0747	negative chemotaxis
AAZ33_RS08160	COG3152	Membrane
AAZ33_RS08200	COG0346	lactoylglutathione lyase activity
AAZ33_RS08220	COG0114	fumarate hydratase activity
AAZ33_RS08225	COG3069	C4-dicarboxylate transmembrane transporter activity
AAZ33_RS08240	COG2079	MmgE PrpD family protein
AAZ33_RS08245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAZ33_RS08250	COG0583	DNA-binding transcription factor activity
AAZ33_RS08335	COG3646	Phage regulatory protein
AAZ33_RS08370	COG3561	AntA/AntB antirepressor
AAZ33_RS08395	COG2026	Addiction module toxin, RelE StbE family
AAZ33_RS08445	COG1342	Belongs to the UPF0251 family
AAZ33_RS08465	COG1342	Belongs to the UPF0251 family
AAZ33_RS08490	COG2995	paraquat-inducible protein a
AAZ33_RS08495	COG1956	GAF domain-containing protein
AAZ33_RS08515	COG3979	chitinase
AAZ33_RS08540	COG3962	Belongs to the TPP enzyme family
AAZ33_RS08545	COG0673	inositol 2-dehydrogenase activity
AAZ33_RS08560	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAZ33_RS08570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAZ33_RS08580	COG3718	enzyme involved in inositol metabolism
AAZ33_RS08585	COG0366	Alpha amylase catalytic
AAZ33_RS08590	COG0501	Belongs to the peptidase M48B family
AAZ33_RS08600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAZ33_RS08615	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS08645	COG2814	Major facilitator Superfamily
AAZ33_RS08650	COG0583	DNA-binding transcription factor activity
AAZ33_RS08680	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AAZ33_RS08685	COG2056	Na+-H+ antiporter family
AAZ33_RS08690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAZ33_RS08695	COG0346	lactoylglutathione lyase activity
AAZ33_RS08705	COG3133	Outer membrane lipoprotein
AAZ33_RS08735	COG0625	glutathione transferase activity
AAZ33_RS08750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAZ33_RS08765	COG4658	electron transport chain
AAZ33_RS08790	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AAZ33_RS08800	COG0385	Bile acid
AAZ33_RS08810	COG5339	Protein conserved in bacteria
AAZ33_RS08835	COG2814	Major facilitator Superfamily
AAZ33_RS08840	COG0583	DNA-binding transcription factor activity
AAZ33_RS08845	COG1940	carbohydrate kinase activity
AAZ33_RS08850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AAZ33_RS08855	COG1858	cytochrome C peroxidase
AAZ33_RS08865	COG0477	Major facilitator Superfamily
AAZ33_RS08880	COG4221	oxidoreductase activity
AAZ33_RS08915	COG3065	identical protein binding
AAZ33_RS08920	COG0840	transmembrane signaling receptor activity
AAZ33_RS08930	COG3691	Protein conserved in bacteria
AAZ33_RS08950	COG0826	peptidase U32
AAZ33_RS08955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAZ33_RS08960	COG0589	response to stress
AAZ33_RS08965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AAZ33_RS08970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AAZ33_RS08980	COG0531	amino acid
AAZ33_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS08995	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS09000	COG2205	protein histidine kinase activity
AAZ33_RS09005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AAZ33_RS09020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAZ33_RS09030	COG3591	Belongs to the peptidase S1B family
AAZ33_RS09035	COG1643	Atp-dependent helicase
AAZ33_RS09040	COG3784	Protein of unknown function (DUF1318)
AAZ33_RS09055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAZ33_RS09065	COG3187	Heat shock protein
AAZ33_RS09075	COG1285	pathogenesis
AAZ33_RS09085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AAZ33_RS09085	COG1013	pyruvate-flavodoxin oxidoreductase activity
AAZ33_RS09085	COG0674	pyruvate-flavodoxin oxidoreductase activity
AAZ33_RS09085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAZ33_RS09090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS09090	COG0493	'glutamate synthase
AAZ33_RS09095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS09095	COG0493	'glutamate synthase
AAZ33_RS09115	COG2050	protein possibly involved in aromatic compounds catabolism
AAZ33_RS09120	COG0247	lactate metabolic process
AAZ33_RS09120	COG0277	FAD linked oxidase domain protein
AAZ33_RS09125	COG0628	permease
AAZ33_RS09130	COG0574	Belongs to the PEP-utilizing enzyme family
AAZ33_RS09130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAZ33_RS09140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAZ33_RS09175	COG4558	Periplasmic binding protein
AAZ33_RS09180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAZ33_RS09200	COG0095	Lipoate-protein ligase
AAZ33_RS09205	COG0791	NLP P60 protein
AAZ33_RS09210	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AAZ33_RS09230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAZ33_RS09230	COG0072	phenylalanine-tRNA ligase activity
AAZ33_RS09260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAZ33_RS09275	COG0783	Belongs to the Dps family
AAZ33_RS09280	COG1105	Belongs to the carbohydrate kinase PfkB family
AAZ33_RS09290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AAZ33_RS09295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAZ33_RS09300	COG1770	oligopeptidase
AAZ33_RS09315	COG3141	response to X-ray
AAZ33_RS09325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AAZ33_RS09345	COG0494	nUDIX hydrolase
AAZ33_RS09350	COG1760	l-serine dehydratase
AAZ33_RS09375	COG1492	cobalamin metabolic process
AAZ33_RS09380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAZ33_RS09400	COG1388	LysM domain
AAZ33_RS09400	COG1376	ErfK ybiS ycfS ynhG family protein
AAZ33_RS09405	COG4166	transmembrane transport
AAZ33_RS09410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AAZ33_RS09425	COG3768	UPF0283 membrane protein
AAZ33_RS09430	COG3106	COG3106 Predicted ATPase
AAZ33_RS09435	COG1983	PspC domain protein
AAZ33_RS09445	COG1842	Phage shock protein A
AAZ33_RS09465	COG4171	peptide transport system, permease
AAZ33_RS09475	COG4172	Belongs to the ABC transporter superfamily
AAZ33_RS09480	COG0668	transmembrane transport
AAZ33_RS09490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AAZ33_RS09500	COG2249	NAD(P)H dehydrogenase (quinone) activity
AAZ33_RS09520	COG1177	transmembrane transport
AAZ33_RS09525	COG0531	amino acid
AAZ33_RS09560	COG0537	adenosine 5'-monophosphoramidase activity
AAZ33_RS09565	COG3678	ATP-independent chaperone mediated protein folding
AAZ33_RS09570	COG3678	ATP-independent chaperone mediated protein folding
AAZ33_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS09695	COG2885	chlorophyll binding
AAZ33_RS09735	COG2885	chlorophyll binding
AAZ33_RS09740	COG2199	diguanylate cyclase activity
AAZ33_RS09755	COG0589	response to stress
AAZ33_RS09760	COG1607	acyl-coa hydrolase
AAZ33_RS09800	COG2169	Transcriptional regulator
AAZ33_RS09805	COG4783	chaperone-mediated protein folding
AAZ33_RS09835	COG0626	cystathionine gamma-synthase activity
AAZ33_RS09840	COG3961	Belongs to the TPP enzyme family
AAZ33_RS09870	COG3250	beta-galactosidase activity
AAZ33_RS09875	COG2246	polysaccharide biosynthetic process
AAZ33_RS09910	COG1596	polysaccharide export
AAZ33_RS09940	COG0297	glycogen (starch) synthase activity
AAZ33_RS09940	COG0438	transferase activity, transferring glycosyl groups
AAZ33_RS09975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAZ33_RS09980	COG1120	ATPase activity
AAZ33_RS10005	COG4264	IucA IucC family
AAZ33_RS10020	COG4772	TonB-dependent receptor
AAZ33_RS10030	COG0738	Major facilitator superfamily
AAZ33_RS10040	COG1349	DNA-binding transcription factor activity
AAZ33_RS10050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AAZ33_RS10060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAZ33_RS10065	COG0066	3-isopropylmalate dehydratase activity
AAZ33_RS10095	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AAZ33_RS10180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AAZ33_RS10185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AAZ33_RS10195	COG3852	Histidine kinase
AAZ33_RS10200	COG2204	response regulator
AAZ33_RS10205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AAZ33_RS10210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AAZ33_RS10215	COG2031	fatty acid transporter
AAZ33_RS10220	COG0183	Belongs to the thiolase family
AAZ33_RS10225	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AAZ33_RS10230	COG0732	type I restriction modification DNA specificity domain
AAZ33_RS10235	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAZ33_RS10250	COG0561	phosphatase activity
AAZ33_RS10340	COG2885	chlorophyll binding
AAZ33_RS10405	COG0741	lytic transglycosylase activity
AAZ33_RS10420	COG4386	tail sheath protein
AAZ33_RS10515	COG1403	HNH endonuclease
AAZ33_RS10525	COG1846	Transcriptional regulator
AAZ33_RS10530	COG3646	Phage regulatory protein
AAZ33_RS10625	COG4974	Belongs to the 'phage' integrase family
AAZ33_RS10690	COG4695	Portal protein
AAZ33_RS10780	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AAZ33_RS10815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAZ33_RS10825	COG2197	response regulator
AAZ33_RS10835	COG3136	membrane protein required for alginate biosynthesis
AAZ33_RS10845	COG0538	isocitrate dehydrogenase activity
AAZ33_RS10875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAZ33_RS10880	COG2188	Transcriptional regulator
AAZ33_RS10885	COG1397	ADP-ribosylglycohydrolase
AAZ33_RS10890	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS10900	COG2850	peptidyl-arginine hydroxylation
AAZ33_RS10915	COG4591	ABC-type transport system involved in lipoprotein release permease component
AAZ33_RS10920	COG1136	(ABC) transporter
AAZ33_RS10925	COG4591	ABC-type transport system involved in lipoprotein release permease component
AAZ33_RS10935	COG3134	Outer membrane lipoprotein
AAZ33_RS10945	COG1252	NADH dehydrogenase
AAZ33_RS10950	COG1349	DNA-binding transcription factor activity
AAZ33_RS10975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAZ33_RS10985	COG0586	Pfam SNARE associated Golgi protein
AAZ33_RS10995	COG0023	Translation Initiation Factor
AAZ33_RS11005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AAZ33_RS11010	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AAZ33_RS11015	COG0671	phosphoesterase, PA-phosphatase related
AAZ33_RS11035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAZ33_RS11035	COG1263	PTS System
AAZ33_RS11040	COG0084	hydrolase, TatD family'
AAZ33_RS11045	COG0470	DNA polymerase III
AAZ33_RS11055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAZ33_RS11060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AAZ33_RS11065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAZ33_RS11080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AAZ33_RS11100	COG1399	metal-binding, possibly nucleic acid-binding protein
AAZ33_RS11115	COG0564	pseudouridine synthase activity
AAZ33_RS11140	COG4619	ABC transporter
AAZ33_RS11145	COG0390	transport system, permease component
AAZ33_RS11150	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AAZ33_RS11150	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AAZ33_RS11160	COG1126	abc transporter atp-binding protein
AAZ33_RS11225	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAZ33_RS11235	COG1157	protein secretion by the type III secretion system
AAZ33_RS11250	COG1580	Controls the rotational direction of flagella during chemotaxis
AAZ33_RS11260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAZ33_RS11285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAZ33_RS11290	COG3108	Peptidase M15
AAZ33_RS11295	COG2989	Protein conserved in bacteria
AAZ33_RS11315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAZ33_RS11320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAZ33_RS11330	COG2233	PERMEase
AAZ33_RS11335	COG3173	Aminoglycoside phosphotransferase
AAZ33_RS11375	COG0539	negative regulation of cytoplasmic translation
AAZ33_RS11400	COG0252	asparaginase activity
AAZ33_RS11405	COG1944	ATP diphosphatase activity
AAZ33_RS11410	COG2116	formate transmembrane transporter activity
AAZ33_RS11415	COG1882	Formate acetyltransferase
AAZ33_RS11420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAZ33_RS11425	COG1309	transcriptional regulator
AAZ33_RS11455	COG2814	Major facilitator Superfamily
AAZ33_RS11460	COG2221	Nitrite and sulphite reductase 4Fe-4S
AAZ33_RS11460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS11470	COG3302	dmso reductase anchor subunit
AAZ33_RS11475	COG0437	4 iron, 4 sulfur cluster binding
AAZ33_RS11480	COG0243	molybdopterin cofactor binding
AAZ33_RS11490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AAZ33_RS11505	COG1522	sequence-specific DNA binding
AAZ33_RS11510	COG0492	ferredoxin-NADP+ reductase activity
AAZ33_RS11530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAZ33_RS11535	COG0542	response to heat
AAZ33_RS11545	COG1278	Cold shock
AAZ33_RS11565	COG2431	L-lysine efflux transmembrane transporter activity
AAZ33_RS11575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAZ33_RS11585	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AAZ33_RS11595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAZ33_RS11600	COG3023	N-Acetylmuramoyl-L-alanine amidase
AAZ33_RS11615	COG3121	Chaperone
AAZ33_RS11620	COG3188	usher protein
AAZ33_RS11630	COG1126	abc transporter atp-binding protein
AAZ33_RS11635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAZ33_RS11640	COG4215	(ABC) transporter
AAZ33_RS11645	COG4160	amino acid transport
AAZ33_RS11650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAZ33_RS11655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAZ33_RS11685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AAZ33_RS11730	COG0671	phosphoesterase, PA-phosphatase related
AAZ33_RS11735	COG1349	DNA-binding transcription factor activity
AAZ33_RS11740	COG0814	amino acid
AAZ33_RS11745	COG1760	l-serine dehydratase
AAZ33_RS11750	COG1686	Belongs to the peptidase S11 family
AAZ33_RS11760	COG1881	PFAM PEBP family protein
AAZ33_RS11765	COG2207	Transcriptional regulator
AAZ33_RS11805	COG3121	Chaperone
AAZ33_RS11810	COG3188	usher protein
AAZ33_RS11825	COG0583	DNA-binding transcription factor activity
AAZ33_RS11835	COG3306	glycosyltransferase involved in LPS biosynthesis
AAZ33_RS11845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAZ33_RS11850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAZ33_RS11885	COG0131	Imidazoleglycerol-phosphate dehydratase
AAZ33_RS11885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AAZ33_RS11910	COG3005	denitrification pathway
AAZ33_RS11915	COG0243	molybdopterin cofactor binding
AAZ33_RS11945	COG0246	Mannitol dehydrogenase
AAZ33_RS11950	COG0840	transmembrane signaling receptor activity
AAZ33_RS11955	COG2200	EAL domain
AAZ33_RS11960	COG2186	Transcriptional regulator
AAZ33_RS11970	COG0523	cobalamin synthesis protein
AAZ33_RS11975	COG0791	NLP P60 protein
AAZ33_RS11980	COG1113	amino acid transport
AAZ33_RS11985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAZ33_RS11985	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AAZ33_RS11985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAZ33_RS11990	COG1105	Belongs to the carbohydrate kinase PfkB family
AAZ33_RS12005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAZ33_RS12010	COG0765	amino acid transport
AAZ33_RS12015	COG1126	abc transporter atp-binding protein
AAZ33_RS12035	COG2814	Major facilitator Superfamily
AAZ33_RS12040	COG1187	pseudouridine synthase activity
AAZ33_RS12060	COG3081	Nucleoid-associated protein
AAZ33_RS12080	COG3706	GGDEF domain
AAZ33_RS12090	COG0589	response to stress
AAZ33_RS12100	COG1309	transcriptional regulator
AAZ33_RS12105	COG2207	Transcriptional regulator
AAZ33_RS12105	COG3708	Transcriptional regulator
AAZ33_RS12110	COG0513	Belongs to the DEAD box helicase family
AAZ33_RS12115	COG1309	transcriptional regulator
AAZ33_RS12125	COG1131	(ABC) transporter
AAZ33_RS12130	COG0842	Transport permease protein
AAZ33_RS12135	COG0842	Transport permease protein
AAZ33_RS12140	COG2198	Histidine kinase
AAZ33_RS12140	COG0642	Histidine kinase
AAZ33_RS12160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAZ33_RS12165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAZ33_RS12170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAZ33_RS12175	COG0243	molybdopterin cofactor binding
AAZ33_RS12180	COG0670	Belongs to the BI1 family
AAZ33_RS12195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AAZ33_RS12230	COG0180	Tryptophanyl-tRNA synthetase
AAZ33_RS12250	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AAZ33_RS12265	COG1169	isochorismate synthase
AAZ33_RS12280	COG1773	rubredoxin
AAZ33_RS12285	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AAZ33_RS12290	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AAZ33_RS12295	COG5557	Pfam Polysulphide reductase, NrfD
AAZ33_RS12305	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AAZ33_RS12315	COG3038	cytochrome b561
AAZ33_RS12325	COG1007	ATP synthesis coupled electron transport
AAZ33_RS12330	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAZ33_RS12335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AAZ33_RS12345	COG0839	Belongs to the complex I subunit 6 family
AAZ33_RS12365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAZ33_RS12370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AAZ33_RS12390	COG0583	DNA-binding transcription factor activity
AAZ33_RS12400	COG2897	thiosulfate sulfurtransferase activity
AAZ33_RS12405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAZ33_RS12410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAZ33_RS12415	COG0436	Aminotransferase
AAZ33_RS12420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AAZ33_RS12425	COG0490	domain, Protein
AAZ33_RS12425	COG0471	metal ion transport
AAZ33_RS12440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAZ33_RS12460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAZ33_RS12465	COG0857	belongs to the CobB CobQ family
AAZ33_RS12465	COG0280	phosphate acetyltransferase
AAZ33_RS12470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAZ33_RS12475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AAZ33_RS12480	COG0622	Phosphoesterase
AAZ33_RS12485	COG0625	glutathione transferase activity
AAZ33_RS12490	COG0625	glutathione transferase activity
AAZ33_RS12495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAZ33_RS12500	COG1090	epimerase
AAZ33_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
AAZ33_RS12510	COG0163	prenyltransferase activity
AAZ33_RS12515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAZ33_RS12520	COG1286	toxin biosynthetic process
AAZ33_RS12530	COG0285	dihydrofolate synthase activity
AAZ33_RS12535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAZ33_RS12540	COG0586	Pfam SNARE associated Golgi protein
AAZ33_RS12550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAZ33_RS12560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAZ33_RS12595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAZ33_RS12610	COG3101	peptidyl-lysine hydroxylation
AAZ33_RS12715	COG2890	protein-(glutamine-N5) methyltransferase activity
AAZ33_RS12725	COG2062	phosphohistidine phosphatase, SixA
AAZ33_RS12730	COG3691	Protein conserved in bacteria
AAZ33_RS12750	COG4235	cytochrome complex assembly
AAZ33_RS12750	COG3088	subunit of a heme lyase
AAZ33_RS12755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAZ33_RS12760	COG1138	Cytochrome C-type biogenesis protein
AAZ33_RS12770	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAZ33_RS12775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAZ33_RS12780	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAZ33_RS12795	COG1566	PFAM secretion protein HlyD family protein
AAZ33_RS12810	COG0582	viral genome integration into host DNA
AAZ33_RS12820	COG5301	cellulose 1,4-beta-cellobiosidase activity
AAZ33_RS12900	COG0740	serine-type endopeptidase activity
AAZ33_RS12935	COG3561	AntA/AntB antirepressor
AAZ33_RS12965	COG1403	HNH endonuclease
AAZ33_RS12970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAZ33_RS13040	COG1475	DNA binding
AAZ33_RS13050	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AAZ33_RS13060	COG2188	Transcriptional regulator
AAZ33_RS13065	COG1082	Xylose isomerase domain protein TIM barrel
AAZ33_RS13070	COG2271	Major facilitator Superfamily
AAZ33_RS13080	COG0583	DNA-binding transcription factor activity
AAZ33_RS13105	COG1619	proteins homologs of microcin C7 resistance protein MccF
AAZ33_RS13155	COG0493	'glutamate synthase
AAZ33_RS13170	COG0640	Transcriptional regulator
AAZ33_RS13175	COG2951	lytic endotransglycosylase activity
AAZ33_RS13185	COG1966	Carbon starvation protein
AAZ33_RS13190	COG2879	small protein
AAZ33_RS13195	COG0523	cobalamin synthesis protein
AAZ33_RS13220	COG4574	serine-type endopeptidase inhibitor activity
AAZ33_RS13225	COG0488	(ABC) transporter
AAZ33_RS13230	COG0583	DNA-binding transcription factor activity
AAZ33_RS13235	COG0840	transmembrane signaling receptor activity
AAZ33_RS13245	COG2801	Transposase and inactivated derivatives
AAZ33_RS13300	COG0641	radical SAM
AAZ33_RS13305	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AAZ33_RS13320	COG3716	PTS system mannose fructose sorbose family IID component
AAZ33_RS13325	COG3715	PTS system
AAZ33_RS13330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAZ33_RS13335	COG2222	sugar isomerase
AAZ33_RS13345	COG1349	DNA-binding transcription factor activity
AAZ33_RS13355	COG1686	Belongs to the peptidase S11 family
AAZ33_RS13370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAZ33_RS13375	COG4628	conserved protein (DUF2132)
AAZ33_RS13400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAZ33_RS13420	COG0477	Major facilitator Superfamily
AAZ33_RS13420	COG2814	Major facilitator Superfamily
AAZ33_RS13425	COG0457	Tetratricopeptide repeat
AAZ33_RS13430	COG1940	carbohydrate kinase activity
AAZ33_RS13435	COG0561	phosphatase activity
AAZ33_RS13445	COG4149	molybdate abc transporter
AAZ33_RS13450	COG0725	ABC transporter, periplasmic molybdate-binding protein
AAZ33_RS13455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAZ33_RS13465	COG3585	molybdate ion transport
AAZ33_RS13465	COG2005	Transcriptional regulator
AAZ33_RS13475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AAZ33_RS13485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AAZ33_RS13490	COG2017	converts alpha-aldose to the beta-anomer
AAZ33_RS13495	COG0471	metal ion transport
AAZ33_RS13505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAZ33_RS13540	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AAZ33_RS13545	COG2885	chlorophyll binding
AAZ33_RS13555	COG3064	Membrane
AAZ33_RS13555	COG3064	Membrane
AAZ33_RS13560	COG0848	biopolymer transport protein
AAZ33_RS13565	COG0811	peptide transport
AAZ33_RS13570	COG0824	Thioesterase
AAZ33_RS13575	COG3790	cyd operon protein YbgE
AAZ33_RS13580	COG1294	oxidase, subunit
AAZ33_RS13585	COG1271	oxidase subunit
AAZ33_RS13590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AAZ33_RS13600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAZ33_RS13605	COG0567	Dehydrogenase, E1 component
AAZ33_RS13610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AAZ33_RS13615	COG1053	succinate dehydrogenase
AAZ33_RS13620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AAZ33_RS13625	COG2009	succinate dehydrogenase
AAZ33_RS13640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAZ33_RS13645	COG2824	Alkylphosphonate utilization operon protein PhnA
AAZ33_RS13660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAZ33_RS13665	COG5212	phosphodiesterase
AAZ33_RS13700	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AAZ33_RS13705	COG2205	protein histidine kinase activity
AAZ33_RS13710	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS13720	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AAZ33_RS13725	COG0596	Alpha beta hydrolase
AAZ33_RS13740	COG0735	belongs to the Fur family
AAZ33_RS13775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAZ33_RS13780	COG1846	Transcriptional regulator
AAZ33_RS13780	COG1940	carbohydrate kinase activity
AAZ33_RS13790	COG0647	UMP catabolic process
AAZ33_RS13795	COG0367	asparagine synthase
AAZ33_RS13835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAZ33_RS13845	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAZ33_RS13850	COG1702	phosphate starvation-inducible protein PhoH
AAZ33_RS13860	COG4535	Mg2 and Co2 transporter CorC
AAZ33_RS13865	COG0686	Belongs to the AlaDH PNT family
AAZ33_RS13870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AAZ33_RS13880	COG0765	amino acid transport
AAZ33_RS13885	COG0765	amino acid transport
AAZ33_RS13890	COG1126	abc transporter atp-binding protein
AAZ33_RS13905	COG2888	peptidyl-tyrosine sulfation
AAZ33_RS13915	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AAZ33_RS13920	COG1466	dna polymerase III delta subunit
AAZ33_RS13930	COG0799	negative regulation of ribosome biogenesis
AAZ33_RS13940	COG0768	penicillin binding
AAZ33_RS13945	COG0772	Belongs to the SEDS family
AAZ33_RS13950	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAZ33_RS13955	COG1686	Belongs to the peptidase S11 family
AAZ33_RS13965	COG0321	lipoyl(octanoyl) transferase activity
AAZ33_RS13985	COG4989	oxidoreductase activity
AAZ33_RS13990	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AAZ33_RS14045	COG0644	oxidoreductase
AAZ33_RS14050	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AAZ33_RS14055	COG2271	Major facilitator Superfamily
AAZ33_RS14070	COG0500	methyltransferase
AAZ33_RS14095	COG1475	DNA binding
AAZ33_RS14100	COG3969	phosphoadenosine phosphosulfate
AAZ33_RS14105	COG3158	transport of potassium into the cell
AAZ33_RS14110	COG0058	SHG alpha-glucan phosphorylase activity
AAZ33_RS14125	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS14135	COG0754	glutathionylspermidine amidase activity
AAZ33_RS14175	COG2501	S4 domain
AAZ33_RS14185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAZ33_RS14195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAZ33_RS14200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AAZ33_RS14215	COG2755	lipolytic protein G-D-S-L family
AAZ33_RS14220	COG0300	oxidoreductase activity
AAZ33_RS14225	COG3118	belongs to the thioredoxin family
AAZ33_RS14230	COG3366	ferrous iron transmembrane transporter activity
AAZ33_RS14235	COG0700	Nucleoside recognition
AAZ33_RS14245	COG2841	Protein conserved in bacteria
AAZ33_RS14260	COG3956	TIGRFAM MazG family protein
AAZ33_RS14285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AAZ33_RS14295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAZ33_RS14305	COG0681	Belongs to the peptidase S26 family
AAZ33_RS14345	COG0513	Belongs to the DEAD box helicase family
AAZ33_RS14355	COG3210	domain, Protein
AAZ33_RS14365	COG3210	domain, Protein
AAZ33_RS14370	COG2831	hemolysin activation secretion protein
AAZ33_RS14390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAZ33_RS14395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AAZ33_RS14405	COG0497	DNA recombination
AAZ33_RS14410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAZ33_RS14420	COG2867	negative regulation of translational initiation
AAZ33_RS14430	COG0582	viral genome integration into host DNA
AAZ33_RS14515	COG5001	Diguanylate cyclase
AAZ33_RS14515	COG4251	negative regulation of phosphorylation
AAZ33_RS14515	COG3706	GGDEF domain
AAZ33_RS14515	COG2203	Gaf domain
AAZ33_RS14525	COG0583	DNA-binding transcription factor activity
AAZ33_RS14530	COG0783	Belongs to the Dps family
AAZ33_RS14540	COG1846	Transcriptional regulator
AAZ33_RS14545	COG1566	PFAM secretion protein HlyD family protein
AAZ33_RS14550	COG2814	Major facilitator Superfamily
AAZ33_RS14555	COG1840	ABC-type Fe3 transport system, periplasmic component
AAZ33_RS14565	COG3842	ATPase activity
AAZ33_RS14570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAZ33_RS14575	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AAZ33_RS14590	COG2860	membrane
AAZ33_RS14610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AAZ33_RS14620	COG0583	DNA-binding transcription factor activity
AAZ33_RS14630	COG2807	transmembrane transport
AAZ33_RS14635	COG2207	Transcriptional regulator
AAZ33_RS14640	COG3547	Transposase (IS116 IS110 IS902 family)
AAZ33_RS14710	COG1737	Transcriptional regulator
AAZ33_RS14725	COG1263	PTS System
AAZ33_RS14725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAZ33_RS14725	COG2190	(PTS) system
AAZ33_RS14730	COG0641	radical SAM
AAZ33_RS14775	COG0517	IMP dehydrogenase activity
AAZ33_RS14775	COG0516	GMP reductase activity
AAZ33_RS14805	COG0437	4 iron, 4 sulfur cluster binding
AAZ33_RS14810	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AAZ33_RS14820	COG1645	bacterial-type flagellum-dependent swarming motility
AAZ33_RS14835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAZ33_RS14840	COG2976	Protein conserved in bacteria
AAZ33_RS14850	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AAZ33_RS14885	COG2975	iron-sulfur cluster assembly
AAZ33_RS14890	COG0633	Ferredoxin
AAZ33_RS14910	COG0822	iron-sulfur transferase activity
AAZ33_RS14925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AAZ33_RS14930	COG0483	inositol monophosphate 1-phosphatase activity
AAZ33_RS14945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAZ33_RS14945	COG1017	nitric oxide dioxygenase activity
AAZ33_RS14955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAZ33_RS14965	COG2226	methyltransferase
AAZ33_RS14975	COG0741	lytic transglycosylase activity
AAZ33_RS14975	COG1388	LysM domain
AAZ33_RS14980	COG3021	interspecies interaction between organisms
AAZ33_RS15015	COG0542	response to heat
AAZ33_RS15025	COG0564	pseudouridine synthase activity
AAZ33_RS15030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAZ33_RS15035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAZ33_RS15040	COG1605	Chorismate mutase
AAZ33_RS15040	COG0077	Prephenate dehydratase
AAZ33_RS15045	COG0287	Prephenate dehydrogenase
AAZ33_RS15045	COG1605	Chorismate mutase
AAZ33_RS15050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAZ33_RS15055	COG3279	Response regulator of the LytR AlgR family
AAZ33_RS15080	COG3137	Salt-induced outer membrane protein
AAZ33_RS15110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAZ33_RS15115	COG4137	Cytochrome C assembly protein
AAZ33_RS15120	COG4536	flavin adenine dinucleotide binding
AAZ33_RS15135	COG1238	metal cluster binding
AAZ33_RS15140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAZ33_RS15170	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AAZ33_RS15180	COG2137	regulation of response to DNA damage stimulus
AAZ33_RS15190	COG1546	Belongs to the CinA family
AAZ33_RS15205	COG0531	amino acid
AAZ33_RS15210	COG2066	Belongs to the glutaminase family
AAZ33_RS15215	COG0531	amino acid
AAZ33_RS15220	COG0076	glutamate decarboxylase activity
AAZ33_RS15225	COG0840	transmembrane signaling receptor activity
AAZ33_RS15250	COG1388	LysM domain
AAZ33_RS15250	COG4942	peptidase
AAZ33_RS15300	COG0861	Integral membrane protein TerC family
AAZ33_RS15325	COG1609	Transcriptional regulator
AAZ33_RS15330	COG1609	Transcriptional regulator
AAZ33_RS15335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS15345	COG0650	Formate hydrogenlyase subunit 4
AAZ33_RS15355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAZ33_RS15360	COG3260	NADH ubiquinone oxidoreductase 20
AAZ33_RS15370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AAZ33_RS15385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS15400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AAZ33_RS15405	COG0298	carbon dioxide binding
AAZ33_RS15410	COG0409	Hydrogenase expression formation protein
AAZ33_RS15415	COG0309	Hydrogenase expression formation protein (HypE)
AAZ33_RS15435	COG0583	DNA-binding transcription factor activity
AAZ33_RS15440	COG3119	arylsulfatase activity
AAZ33_RS15465	COG1560	Kdo2-lipid A biosynthetic process
AAZ33_RS15470	COG3133	Outer membrane lipoprotein
AAZ33_RS15505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AAZ33_RS15515	COG4974	Belongs to the 'phage' integrase family
AAZ33_RS15520	COG0716	FMN binding
AAZ33_RS15530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AAZ33_RS15540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAZ33_RS15545	COG3248	Nucleoside-binding outer membrane protein
AAZ33_RS15550	COG1272	protein, Hemolysin III
AAZ33_RS15555	COG1115	amino acid carrier protein
AAZ33_RS15575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAZ33_RS15580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAZ33_RS15585	COG0006	proline dipeptidase activity
AAZ33_RS15600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAZ33_RS15605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAZ33_RS15625	COG1279	arginine transmembrane transporter activity
AAZ33_RS15640	COG0126	phosphoglycerate kinase activity
AAZ33_RS15650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAZ33_RS15655	COG3119	arylsulfatase activity
AAZ33_RS15665	COG1166	arginine decarboxylase activity
AAZ33_RS15675	COG2814	Major facilitator Superfamily
AAZ33_RS15680	COG0312	modulator of DNA gyrase
AAZ33_RS15685	COG2916	Histone family protein nucleoid-structuring protein H-NS
AAZ33_RS15695	COG2732	(Barnase) inhibitor
AAZ33_RS15705	COG2723	6-phospho-beta-galactosidase activity
AAZ33_RS15725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AAZ33_RS15730	COG0583	DNA-binding transcription factor activity
AAZ33_RS15735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AAZ33_RS15765	COG2211	Major facilitator Superfamily
AAZ33_RS15775	COG2197	response regulator
AAZ33_RS15790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AAZ33_RS15795	COG0583	DNA-binding transcription factor activity
AAZ33_RS15805	COG1294	oxidase, subunit
AAZ33_RS15810	COG1271	oxidase subunit
AAZ33_RS15825	COG1999	signal sequence binding
AAZ33_RS15830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AAZ33_RS15835	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AAZ33_RS15840	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AAZ33_RS15845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AAZ33_RS15850	COG1982	Orn Lys Arg decarboxylase major
AAZ33_RS15855	COG0531	amino acid
AAZ33_RS15860	COG1982	Orn Lys Arg decarboxylase major
AAZ33_RS15870	COG2223	nitrite transmembrane transporter activity
AAZ33_RS15875	COG3279	Response regulator of the LytR AlgR family
AAZ33_RS15880	COG3275	phosphorelay sensor kinase activity
AAZ33_RS15885	COG1486	melibiose metabolic process
AAZ33_RS15895	COG1129	ABC transporter
AAZ33_RS15930	COG3250	beta-galactosidase activity
AAZ33_RS15940	COG1609	Transcriptional regulator
AAZ33_RS15945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAZ33_RS15955	COG3037	sugar-specific permease SgaT UlaA
AAZ33_RS15965	COG3023	N-Acetylmuramoyl-L-alanine amidase
AAZ33_RS15970	COG1605	Chorismate mutase
AAZ33_RS16005	COG1376	ErfK ybiS ycfS ynhG family protein
AAZ33_RS16010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AAZ33_RS16015	COG0795	lipopolysaccharide-transporting ATPase activity
AAZ33_RS16020	COG0795	lipopolysaccharide-transporting ATPase activity
AAZ33_RS16030	COG2927	DNA polymerase III (CHI subunit)
AAZ33_RS16040	COG4176	ABC-type proline glycine betaine transport system permease component
AAZ33_RS16045	COG1116	anion transmembrane transporter activity
AAZ33_RS16050	COG0456	acetyltransferase
AAZ33_RS16060	COG3457	Alanine racemase
AAZ33_RS16065	COG0531	amino acid
AAZ33_RS16075	COG3829	transcription factor binding
AAZ33_RS16090	COG2731	YhcH YjgK YiaL family protein
AAZ33_RS16095	COG0247	lactate metabolic process
AAZ33_RS16105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AAZ33_RS16110	COG2271	Major facilitator Superfamily
AAZ33_RS16115	COG0584	glycerophosphoryl diester phosphodiesterase
AAZ33_RS16125	COG0625	glutathione transferase activity
AAZ33_RS16140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AAZ33_RS16155	COG0540	Belongs to the ATCase OTCase family
AAZ33_RS16165	COG1566	PFAM secretion protein HlyD family protein
AAZ33_RS16175	COG0583	DNA-binding transcription factor activity
AAZ33_RS16185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAZ33_RS16190	COG3164	Protein of unknown function
AAZ33_RS16205	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AAZ33_RS16215	COG1077	Cell shape determining protein MreB Mrl
AAZ33_RS16220	COG2200	EAL domain
AAZ33_RS16220	COG2199	diguanylate cyclase activity
AAZ33_RS16235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AAZ33_RS16250	COG0511	ligase activity, forming carbon-carbon bonds
AAZ33_RS16255	COG0439	Biotin carboxylase
AAZ33_RS16260	COG3924	membrane
AAZ33_RS16265	COG4145	pantothenate transmembrane transporter activity
AAZ33_RS16285	COG3119	arylsulfatase activity
AAZ33_RS16325	COG3547	Transposase (IS116 IS110 IS902 family)
AAZ33_RS16375	COG4669	(LipO)protein
AAZ33_RS16435	COG1346	cytolysis
AAZ33_RS16440	COG1380	Effector of murein hydrolase LrgA
AAZ33_RS16445	COG0583	DNA-binding transcription factor activity
AAZ33_RS16450	COG0025	NhaP-type Na H and K H
AAZ33_RS16455	COG2252	PERMEase
AAZ33_RS16460	COG0402	S-adenosylhomocysteine deaminase activity
AAZ33_RS16465	COG2233	PERMEase
AAZ33_RS16470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AAZ33_RS16470	COG2080	2 iron, 2 sulfur cluster binding
AAZ33_RS16475	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AAZ33_RS16480	COG0402	S-adenosylhomocysteine deaminase activity
AAZ33_RS16485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAZ33_RS16485	COG0493	'glutamate synthase
AAZ33_RS16490	COG2068	MobA-Related Protein
AAZ33_RS16495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAZ33_RS16500	COG3608	succinylglutamate desuccinylase aspartoacylase
AAZ33_RS16500	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AAZ33_RS16505	COG0549	Belongs to the carbamate kinase family
AAZ33_RS16515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAZ33_RS16520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAZ33_RS16525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAZ33_RS16530	COG3829	transcription factor binding
AAZ33_RS16545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AAZ33_RS16550	COG2315	Protein conserved in bacteria
AAZ33_RS16555	COG0432	Pfam Uncharacterised protein family UPF0047
AAZ33_RS16565	COG0656	L-ascorbic acid biosynthetic process
AAZ33_RS16630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AAZ33_RS16650	COG0551	DNA topoisomerase type I activity
AAZ33_RS16655	COG2922	Belongs to the Smg family
AAZ33_RS16675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAZ33_RS16675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAZ33_RS16680	COG0569	domain protein
AAZ33_RS16685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AAZ33_RS16690	COG1970	mechanosensitive ion channel activity
AAZ33_RS16695	COG0789	Transcriptional regulator
AAZ33_RS16730	COG0201	protein transport
AAZ33_RS16765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAZ33_RS16785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAZ33_RS16805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAZ33_RS16830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAZ33_RS16835	COG0051	transcription antitermination factor activity, RNA binding
AAZ33_RS16860	COG2168	tRNA wobble position uridine thiolation
AAZ33_RS16875	COG2964	Protein conserved in bacteria
AAZ33_RS16880	COG0545	Peptidyl-prolyl cis-trans isomerase
AAZ33_RS16890	COG1047	Peptidyl-prolyl cis-trans
AAZ33_RS16895	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AAZ33_RS16905	COG2249	NAD(P)H dehydrogenase (quinone) activity
AAZ33_RS16910	COG0488	(ABC) transporter
AAZ33_RS16925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAZ33_RS16935	COG0402	S-adenosylhomocysteine deaminase activity
AAZ33_RS16940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAZ33_RS16950	COG0180	Tryptophanyl-tRNA synthetase
AAZ33_RS16955	COG0546	phosphoglycolate phosphatase activity
AAZ33_RS16960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAZ33_RS16980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAZ33_RS17010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AAZ33_RS17015	COG0494	nUDIX hydrolase
AAZ33_RS17025	COG1011	Hydrolase
AAZ33_RS17030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AAZ33_RS17040	COG0437	4 iron, 4 sulfur cluster binding
AAZ33_RS17045	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AAZ33_RS17050	COG0484	heat shock protein binding
AAZ33_RS17075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAZ33_RS17080	COG2183	response to ionizing radiation
AAZ33_RS17085	COG1918	ferrous iron import across plasma membrane
AAZ33_RS17090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AAZ33_RS17125	COG3037	sugar-specific permease SgaT UlaA
AAZ33_RS17155	COG1289	transmembrane transporter activity
AAZ33_RS17160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAZ33_RS17170	COG0429	hydrolase of the alpha beta-hydrolase fold
AAZ33_RS17180	COG2909	trisaccharide binding
AAZ33_RS17185	COG0058	SHG alpha-glucan phosphorylase activity
AAZ33_RS17195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AAZ33_RS17200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AAZ33_RS17205	COG1523	belongs to the glycosyl hydrolase 13 family
AAZ33_RS17210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AAZ33_RS17220	COG0058	SHG alpha-glucan phosphorylase activity
AAZ33_RS17225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AAZ33_RS17230	COG1349	DNA-binding transcription factor activity
AAZ33_RS17235	COG0705	Rhomboid family
AAZ33_RS17260	COG0395	ABC-type sugar transport system, permease component
AAZ33_RS17275	COG0456	acetyltransferase
AAZ33_RS17280	COG1929	Belongs to the glycerate kinase type-1 family
AAZ33_RS17285	COG2610	gluconate transmembrane transporter activity
AAZ33_RS17300	COG2177	Part of the ABC transporter FtsEX involved in
AAZ33_RS17305	COG2884	Cell division ATP-binding protein ftsE
AAZ33_RS17310	COG0552	protein localization to endoplasmic reticulum
AAZ33_RS17310	COG0552	protein localization to endoplasmic reticulum
AAZ33_RS17315	COG0742	ribosomal rna small subunit methyltransferase
AAZ33_RS17320	COG3776	membrane
AAZ33_RS17335	COG3714	YhhN family
AAZ33_RS17340	COG2258	MOSC domain
AAZ33_RS17350	COG0243	molybdopterin cofactor binding
AAZ33_RS17350	COG3383	formate dehydrogenase (NAD+) activity
AAZ33_RS17355	COG3383	formate dehydrogenase (NAD+) activity
AAZ33_RS17355	COG0243	molybdopterin cofactor binding
AAZ33_RS17360	COG0437	4 iron, 4 sulfur cluster binding
AAZ33_RS17365	COG2864	formate dehydrogenase
AAZ33_RS17385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAZ33_RS17390	COG3275	phosphorelay sensor kinase activity
AAZ33_RS17400	COG0306	phosphate transporter
AAZ33_RS17405	COG0733	neurotransmitter:sodium symporter activity
AAZ33_RS17415	COG0589	response to stress
AAZ33_RS17430	COG5002	protein histidine kinase activity
AAZ33_RS17435	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS17445	COG1129	ABC transporter
AAZ33_RS17450	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAZ33_RS17455	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAZ33_RS17465	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AAZ33_RS17465	COG0517	IMP dehydrogenase activity
AAZ33_RS17475	COG0339	signal peptide processing
AAZ33_RS17485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AAZ33_RS17490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAZ33_RS17505	COG1181	Belongs to the D-alanine--D-alanine ligase family
AAZ33_RS17515	COG0583	DNA-binding transcription factor activity
AAZ33_RS17520	COG2134	cdp-diacylglycerol pyrophosphatase
AAZ33_RS17525	COG2200	EAL domain
AAZ33_RS17530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAZ33_RS17545	COG2200	EAL domain
AAZ33_RS17545	COG2199	diguanylate cyclase activity
AAZ33_RS17555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AAZ33_RS17560	COG1215	transferase activity, transferring glycosyl groups
AAZ33_RS17565	COG1215	transferase activity, transferring glycosyl groups
AAZ33_RS17570	COG1192	Involved in chromosome partitioning
AAZ33_RS17595	COG4608	Belongs to the ABC transporter superfamily
AAZ33_RS17600	COG0444	Belongs to the ABC transporter superfamily
AAZ33_RS17605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAZ33_RS17610	COG0601	transmembrane transport
AAZ33_RS17615	COG0747	negative chemotaxis
AAZ33_RS17620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAZ33_RS17635	COG2271	Major facilitator Superfamily
AAZ33_RS17650	COG0840	transmembrane signaling receptor activity
AAZ33_RS17655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAZ33_RS17660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AAZ33_RS17665	COG2207	Transcriptional regulator
AAZ33_RS17705	COG0460	homoserine dehydrogenase
AAZ33_RS17705	COG0527	aspartate kinase activity
AAZ33_RS17710	COG0626	cystathionine gamma-synthase activity
AAZ33_RS17725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAZ33_RS17730	COG1609	Transcriptional regulator
AAZ33_RS17735	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAZ33_RS17740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AAZ33_RS17750	COG1575	Belongs to the MenA family. Type 1 subfamily
AAZ33_RS17765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AAZ33_RS17775	COG1494	fructose-1,6-bisphosphatase
AAZ33_RS17780	COG2814	Major facilitator Superfamily
AAZ33_RS17795	COG3152	Membrane
AAZ33_RS17805	COG0149	triose-phosphate isomerase activity
AAZ33_RS17815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AAZ33_RS17820	COG3678	ATP-independent chaperone mediated protein folding
AAZ33_RS17825	COG0745	RESPONSE REGULATOR receiver
AAZ33_RS17830	COG2205	protein histidine kinase activity
AAZ33_RS17835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AAZ33_RS17840	COG1045	serine acetyltransferase
AAZ33_RS17855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AAZ33_RS17860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAZ33_RS17865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAZ33_RS17870	COG4942	peptidase
AAZ33_RS17875	COG2861	carbohydrate metabolic process
AAZ33_RS17880	COG3085	chromosome segregation
AAZ33_RS17925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AAZ33_RS17935	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AAZ33_RS17965	COG1309	transcriptional regulator
AAZ33_RS17970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAZ33_RS17980	COG0678	peroxiredoxin activity
AAZ33_RS17980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AAZ33_RS17985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAZ33_RS18020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AAZ33_RS18045	COG1295	ribonuclease BN
AAZ33_RS18050	COG1011	Hydrolase
AAZ33_RS18055	COG1217	gtp-binding protein TYPA
AAZ33_RS18065	COG3852	Histidine kinase
AAZ33_RS18080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAZ33_RS18095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAZ33_RS18095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAZ33_RS18100	COG0204	Acyl-transferase
AAZ33_RS18105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAZ33_RS18110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AAZ33_RS18115	COG3084	Protein conserved in bacteria
AAZ33_RS18120	COG0746	molybdenum cofactor guanylyltransferase activity
AAZ33_RS18125	COG1763	Mo-molybdopterin cofactor biosynthetic process
AAZ33_RS18165	COG2186	Transcriptional regulator
AAZ33_RS18170	COG0477	Major facilitator Superfamily
AAZ33_RS18175	COG1609	Transcriptional regulator
AAZ33_RS18180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAZ33_RS18185	COG1879	ABC-type sugar transport system periplasmic component
AAZ33_RS18190	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAZ33_RS18195	COG1129	ABC transporter
AAZ33_RS18205	COG3158	transport of potassium into the cell
AAZ33_RS18225	COG1522	sequence-specific DNA binding
AAZ33_RS18230	COG0716	FMN binding
AAZ33_RS18245	COG3312	ion transport
AAZ33_RS18260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAZ33_RS18305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AAZ33_RS18310	COG0573	inorganic phosphate transmembrane transporter activity
AAZ33_RS18315	COG0581	inorganic phosphate transmembrane transporter activity
AAZ33_RS18330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAZ33_RS18340	COG2252	PERMEase
AAZ33_RS18350	COG0398	Pfam SNARE associated Golgi protein
AAZ33_RS18355	COG2840	Smr protein MutS2
AAZ33_RS18390	COG0697	spore germination
AAZ33_RS18395	COG3151	Protein conserved in bacteria
AAZ33_RS18405	COG0735	belongs to the Fur family
AAZ33_RS18435	COG1923	regulation of RNA biosynthetic process
AAZ33_RS18440	COG2965	DNA replication, synthesis of RNA primer
AAZ33_RS18535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAZ33_RS18555	COG3969	phosphoadenosine phosphosulfate
AAZ33_RS18610	COG3210	domain, Protein
AAZ33_RS18645	COG0776	regulation of translation
AAZ33_RS18670	COG1940	carbohydrate kinase activity
AAZ33_RS18685	COG1216	Glycosyl transferase, family 2
AAZ33_RS18695	COG1215	transferase activity, transferring glycosyl groups
AAZ33_RS18700	COG0438	transferase activity, transferring glycosyl groups
AAZ33_RS18710	COG0463	Glycosyl transferase, family 2
AAZ33_RS18725	COG3130	regulation of translation
AAZ33_RS18730	COG3785	DNA binding
AAZ33_RS18740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAZ33_RS18750	COG1278	Cold shock
AAZ33_RS18780	COG2186	Transcriptional regulator
AAZ33_RS18850	COG0183	Belongs to the thiolase family
AAZ33_RS18980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AAZ33_RS19060	COG3468	outer membrane autotransporter barrel domain protein
AAZ33_RS19120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAZ33_RS19165	COG3969	phosphoadenosine phosphosulfate
AAZ33_RS19180	COG4890	Cyd operon protein YbgT
AAZ33_RS19185	COG0582	viral genome integration into host DNA
AAZ33_RS19205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AAZ33_RS19275	COG2149	membrane
AAZ33_RS19295	COG3088	subunit of a heme lyase
AAZ33_RS19295	COG4235	cytochrome complex assembly
AAZ33_RS19455	COG0257	Belongs to the bacterial ribosomal protein bL36 family