locus-tag	class	description
CPU03_RS00005	COG2200	EAL domain
CPU03_RS00015	COG3141	response to X-ray
CPU03_RS00025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CPU03_RS00045	COG0494	nUDIX hydrolase
CPU03_RS00050	COG1760	l-serine dehydratase
CPU03_RS00070	COG1115	amino acid carrier protein
CPU03_RS00075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPU03_RS00085	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CPU03_RS00095	COG5301	cellulose 1,4-beta-cellobiosidase activity
CPU03_RS00095	COG5301	cellulose 1,4-beta-cellobiosidase activity
CPU03_RS00205	COG4220	transposase activity
CPU03_RS00235	COG3772	lysozyme
CPU03_RS00255	COG1403	HNH endonuclease
CPU03_RS00260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CPU03_RS00265	COG3645	SOS response
CPU03_RS00265	COG3646	Phage regulatory protein
CPU03_RS00325	COG3655	Transcriptional regulator
CPU03_RS00350	COG1475	DNA binding
CPU03_RS00360	COG0582	viral genome integration into host DNA
CPU03_RS00365	COG1115	amino acid carrier protein
CPU03_RS00370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CPU03_RS00380	COG1492	cobalamin metabolic process
CPU03_RS00385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPU03_RS00400	COG1376	ErfK ybiS ycfS ynhG family protein
CPU03_RS00400	COG1388	LysM domain
CPU03_RS00405	COG4166	transmembrane transport
CPU03_RS00410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPU03_RS00420	COG2897	thiosulfate sulfurtransferase activity
CPU03_RS00425	COG3768	UPF0283 membrane protein
CPU03_RS00430	COG3106	COG3106 Predicted ATPase
CPU03_RS00440	COG1983	PspC domain protein
CPU03_RS00450	COG1842	Phage shock protein A
CPU03_RS00455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CPU03_RS00470	COG4171	peptide transport system, permease
CPU03_RS00480	COG4172	Belongs to the ABC transporter superfamily
CPU03_RS00485	COG0668	transmembrane transport
CPU03_RS00505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPU03_RS00515	COG0814	amino acid
CPU03_RS00520	COG2249	NAD(P)H dehydrogenase (quinone) activity
CPU03_RS00540	COG1177	transmembrane transport
CPU03_RS00545	COG0531	amino acid
CPU03_RS00565	COG0510	thiamine kinase activity
CPU03_RS00575	COG5633	Lipoprotein
CPU03_RS00580	COG0537	adenosine 5'-monophosphoramidase activity
CPU03_RS00595	COG3678	ATP-independent chaperone mediated protein folding
CPU03_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
CPU03_RS00620	COG0494	nUDIX hydrolase
CPU03_RS00625	COG1794	racemase activity, acting on amino acids and derivatives
CPU03_RS00655	COG3152	Membrane
CPU03_RS00665	COG0601	transmembrane transport
CPU03_RS00670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPU03_RS00680	COG1124	(ABC) transporter
CPU03_RS00685	COG0814	amino acid
CPU03_RS00700	COG3001	Fructosamine kinase
CPU03_RS00710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPU03_RS00715	COG1988	membrane-bound metal-dependent
CPU03_RS00720	COG1823	symporter activity
CPU03_RS00730	COG2814	Major facilitator Superfamily
CPU03_RS00735	COG0307	riboflavin synthase, alpha
CPU03_RS00775	COG2200	EAL domain
CPU03_RS00780	COG1253	flavin adenine dinucleotide binding
CPU03_RS00790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS00790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPU03_RS00795	COG3715	PTS system
CPU03_RS00800	COG3716	PTS system mannose fructose sorbose family IID component
CPU03_RS00810	COG2226	methyltransferase
CPU03_RS00840	COG0616	signal peptide processing
CPU03_RS00845	COG1028	Short-chain dehydrogenase reductase Sdr
CPU03_RS00855	COG0406	alpha-ribazole phosphatase activity
CPU03_RS00865	COG1187	pseudouridine synthase activity
CPU03_RS00880	COG2207	Transcriptional regulator
CPU03_RS00885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CPU03_RS00890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPU03_RS00895	COG0765	amino acid transport
CPU03_RS00905	COG0009	L-threonylcarbamoyladenylate synthase
CPU03_RS00910	COG0613	PHP domain protein
CPU03_RS00920	COG0512	Glutamine amidotransferase of anthranilate synthase
CPU03_RS00925	COG0512	Glutamine amidotransferase of anthranilate synthase
CPU03_RS00925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CPU03_RS00930	COG0134	indole-3-glycerol-phosphate synthase activity
CPU03_RS00930	COG0135	phosphoribosylanthranilate isomerase activity
CPU03_RS00945	COG2823	Periplasmic or secreted lipoprotein
CPU03_RS00955	COG0727	PFAM Uncharacterised protein family (UPF0153)
CPU03_RS00985	COG1607	acyl-coa hydrolase
CPU03_RS00995	COG2350	Protein conserved in bacteria
CPU03_RS01000	COG0783	Belongs to the Dps family
CPU03_RS01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPU03_RS01035	COG0601	transmembrane transport
CPU03_RS01045	COG2095	MarC family integral membrane protein
CPU03_RS01050	COG1454	alcohol dehydrogenase
CPU03_RS01050	COG1012	belongs to the aldehyde dehydrogenase family
CPU03_RS01060	COG1435	thymidine kinase activity
CPU03_RS01065	COG2916	Histone family protein nucleoid-structuring protein H-NS
CPU03_RS01070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPU03_RS01075	COG0745	RESPONSE REGULATOR receiver
CPU03_RS01080	COG3012	SEC-C Motif Domain Protein
CPU03_RS01085	COG0788	formyltetrahydrofolate deformylase activity
CPU03_RS01105	COG0708	Exodeoxyribonuclease III
CPU03_RS01110	COG0494	nUDIX hydrolase
CPU03_RS01120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPU03_RS01125	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CPU03_RS01135	COG0778	Nitroreductase
CPU03_RS01140	COG0616	signal peptide processing
CPU03_RS01145	COG0252	asparaginase activity
CPU03_RS01150	COG1335	isochorismatase
CPU03_RS01155	COG3139	Protein of unknown function (DUF1315)
CPU03_RS01160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPU03_RS01170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPU03_RS01175	COG1393	Belongs to the ArsC family
CPU03_RS01185	COG3188	usher protein
CPU03_RS01190	COG3121	Chaperone
CPU03_RS01220	COG3713	MltA-interacting MipA family protein
CPU03_RS01225	COG2766	serine protein kinase
CPU03_RS01240	COG3104	oligopeptide transport
CPU03_RS01245	COG1362	aminopeptidase activity
CPU03_RS01260	COG2719	SpoVR family
CPU03_RS01280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CPU03_RS01285	COG0589	response to stress
CPU03_RS01295	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPU03_RS01310	COG2894	cell division
CPU03_RS01320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CPU03_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
CPU03_RS01330	COG3065	identical protein binding
CPU03_RS01340	COG1199	ATP-dependent helicase activity
CPU03_RS01345	COG0251	oxidation-reduction process
CPU03_RS01355	COG2076	Multidrug Resistance protein
CPU03_RS01360	COG0800	Aldolase
CPU03_RS01365	COG0129	dihydroxy-acid dehydratase activity
CPU03_RS01370	COG0363	glucosamine-6-phosphate deaminase activity
CPU03_RS01375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CPU03_RS01380	COG1737	Transcriptional regulator
CPU03_RS01385	COG0469	pyruvate kinase activity
CPU03_RS01390	COG0730	response to heat
CPU03_RS01395	COG1560	Kdo2-lipid A biosynthetic process
CPU03_RS01400	COG0739	heme binding
CPU03_RS01405	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CPU03_RS01410	COG1121	(ABC) transporter
CPU03_RS01415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPU03_RS01440	COG0494	nUDIX hydrolase
CPU03_RS01455	COG1801	Protein of unknown function DUF72
CPU03_RS01460	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CPU03_RS01465	COG1113	amino acid transport
CPU03_RS01490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CPU03_RS01495	COG3102	Protein conserved in bacteria
CPU03_RS01505	COG0728	peptidoglycan biosynthetic process
CPU03_RS01510	COG3132	Protein of unknown function, DUF480
CPU03_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPU03_RS01530	COG3381	protein complex oligomerization
CPU03_RS01545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPU03_RS01555	COG4134	Bacterial extracellular solute-binding protein
CPU03_RS01580	COG0659	secondary active sulfate transmembrane transporter activity
CPU03_RS01600	COG2890	protein-(glutamine-N5) methyltransferase activity
CPU03_RS01615	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CPU03_RS01625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPU03_RS01645	COG0012	GTP binding
CPU03_RS01670	COG0513	Belongs to the DEAD box helicase family
CPU03_RS01675	COG3122	Protein conserved in bacteria
CPU03_RS01680	COG0583	DNA-binding transcription factor activity
CPU03_RS01690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPU03_RS01695	COG3069	C4-dicarboxylate transmembrane transporter activity
CPU03_RS01700	COG3493	citrate carrier protein
CPU03_RS01705	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPU03_RS01715	COG0583	DNA-binding transcription factor activity
CPU03_RS01720	COG3069	C4-dicarboxylate transmembrane transporter activity
CPU03_RS01725	COG1473	amidohydrolase
CPU03_RS01730	COG5645	(Lipo)protein
CPU03_RS01735	COG0586	Pfam SNARE associated Golgi protein
CPU03_RS01740	COG0387	Pfam Sodium calcium exchanger
CPU03_RS01745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CPU03_RS01750	COG0745	RESPONSE REGULATOR receiver
CPU03_RS01755	COG2201	protein-glutamate methylesterase activity
CPU03_RS01760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CPU03_RS01765	COG0840	transmembrane signaling receptor activity
CPU03_RS01770	COG0840	transmembrane signaling receptor activity
CPU03_RS01775	COG0835	chemotaxis
CPU03_RS01780	COG0643	Histidine kinase
CPU03_RS01780	COG2198	Histidine kinase
CPU03_RS01805	COG1979	alcohol dehydrogenase
CPU03_RS01820	COG0768	penicillin binding
CPU03_RS01825	COG2194	sulfuric ester hydrolase activity
CPU03_RS01830	COG1335	isochorismatase
CPU03_RS01835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPU03_RS01840	COG2207	Transcriptional regulator
CPU03_RS01890	COG3042	response to heat
CPU03_RS01930	COG1278	Cold shock
CPU03_RS01940	COG1278	Cold shock
CPU03_RS01950	COG2076	Multidrug Resistance protein
CPU03_RS01990	COG2271	Major facilitator Superfamily
CPU03_RS01995	COG1280	lysine exporter protein (LysE YggA)
CPU03_RS02005	COG0670	Belongs to the BI1 family
CPU03_RS02010	COG2920	part of a sulfur-relay system
CPU03_RS02015	COG1254	Belongs to the acylphosphatase family
CPU03_RS02025	COG3785	DNA binding
CPU03_RS02030	COG1832	CoA-binding protein
CPU03_RS02045	COG0210	DNA helicase
CPU03_RS02050	COG3304	Inner membrane component domain
CPU03_RS02055	COG1289	transmembrane transporter activity
CPU03_RS02060	COG3070	regulator of competence-specific genes
CPU03_RS02075	COG3120	sequence-specific DNA binding
CPU03_RS02080	COG1067	ATP-dependent peptidase activity
CPU03_RS02090	COG3130	regulation of translation
CPU03_RS02095	COG3009	Protein conserved in bacteria
CPU03_RS02100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CPU03_RS02100	COG3008	intermembrane lipid transfer
CPU03_RS02105	COG2995	paraquat-inducible protein a
CPU03_RS02110	COG0488	(ABC) transporter
CPU03_RS02115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CPU03_RS02115	COG0116	Belongs to the methyltransferase superfamily
CPU03_RS02150	COG0308	aminopeptidase N
CPU03_RS02180	COG3059	membrane
CPU03_RS02205	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CPU03_RS02210	COG4786	Flagellar basal body rod
CPU03_RS02230	COG1558	bacterial-type flagellum-dependent cell motility
CPU03_RS02235	COG1815	bacterial-type flagellum-dependent cell motility
CPU03_RS02245	COG2747	anti-sigma28 factor FlgM
CPU03_RS02260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPU03_RS02265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPU03_RS02275	COG2194	sulfuric ester hydrolase activity
CPU03_RS02290	COG0583	DNA-binding transcription factor activity
CPU03_RS02295	COG0814	amino acid
CPU03_RS02300	COG0626	cystathionine gamma-synthase activity
CPU03_RS02345	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CPU03_RS02385	COG0463	Glycosyl transferase, family 2
CPU03_RS02385	COG1216	Glycosyl transferase, family 2
CPU03_RS02400	COG2244	polysaccharide biosynthetic process
CPU03_RS02415	COG1091	dTDP-4-dehydrorhamnose reductase activity
CPU03_RS02425	COG3069	C4-dicarboxylate transmembrane transporter activity
CPU03_RS02430	COG2982	Protein involved in outer membrane biogenesis
CPU03_RS02440	COG0697	spore germination
CPU03_RS02445	COG0572	uridine kinase
CPU03_RS02450	COG0489	protein tyrosine kinase activity
CPU03_RS02455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPU03_RS02455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPU03_RS02465	COG0833	amino acid
CPU03_RS02470	COG0583	DNA-binding transcription factor activity
CPU03_RS02485	COG2855	membrane
CPU03_RS02495	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CPU03_RS02505	COG1289	transmembrane transporter activity
CPU03_RS02510	COG2925	Exonuclease
CPU03_RS02515	COG2962	Rard protein
CPU03_RS02520	COG1380	Effector of murein hydrolase LrgA
CPU03_RS02525	COG1346	cytolysis
CPU03_RS02545	COG2949	membrane
CPU03_RS02550	COG2200	EAL domain
CPU03_RS02550	COG2199	diguanylate cyclase activity
CPU03_RS02555	COG2311	Membrane
CPU03_RS02565	COG0303	'Molybdopterin
CPU03_RS02570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CPU03_RS02575	COG2943	transferase activity, transferring hexosyl groups
CPU03_RS02580	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CPU03_RS02605	COG1914	H( )-stimulated, divalent metal cation uptake system
CPU03_RS02610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPU03_RS02640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPU03_RS02685	COG3530	Putative quorum-sensing-regulated virulence factor
CPU03_RS02690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPU03_RS02695	COG3115	cell septum assembly
CPU03_RS02710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS02720	COG2190	(PTS) system
CPU03_RS02725	COG2837	iron assimilation
CPU03_RS02735	COG0456	acetyltransferase
CPU03_RS02740	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPU03_RS02745	COG0408	coproporphyrinogen oxidase activity
CPU03_RS02750	COG1671	Belongs to the UPF0178 family
CPU03_RS02760	COG0281	malic enzyme
CPU03_RS02760	COG0280	phosphate acetyltransferase
CPU03_RS02765	COG0494	nUDIX hydrolase
CPU03_RS02770	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS02775	COG2414	aldehyde ferredoxin oxidoreductase
CPU03_RS02785	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS02795	COG3005	denitrification pathway
CPU03_RS02800	COG3043	anaerobic respiration
CPU03_RS02805	COG0348	domain, Protein
CPU03_RS02810	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS02820	COG3062	negative regulation of establishment of protein localization
CPU03_RS02825	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS02825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS02830	COG3850	Histidine kinase
CPU03_RS02835	COG2197	response regulator
CPU03_RS02845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPU03_RS02850	COG1393	Belongs to the ArsC family
CPU03_RS02855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPU03_RS02860	COG1876	peptidase activity
CPU03_RS02870	COG0400	carboxylic ester hydrolase activity
CPU03_RS02875	COG1444	tRNA N-acetyltransferase activity
CPU03_RS02885	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CPU03_RS02895	COG2716	regulation of RNA biosynthetic process
CPU03_RS02900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPU03_RS02905	COG0628	permease
CPU03_RS02910	COG4783	chaperone-mediated protein folding
CPU03_RS02915	COG1393	Belongs to the ArsC family
CPU03_RS02920	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CPU03_RS02925	COG2233	PERMEase
CPU03_RS02940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPU03_RS02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPU03_RS02960	COG5002	protein histidine kinase activity
CPU03_RS02965	COG0745	RESPONSE REGULATOR receiver
CPU03_RS02970	COG0420	3'-5' exonuclease activity
CPU03_RS02975	COG0419	ATPase involved in DNA repair
CPU03_RS02990	COG1940	carbohydrate kinase activity
CPU03_RS03025	COG2205	protein histidine kinase activity
CPU03_RS03030	COG0745	RESPONSE REGULATOR receiver
CPU03_RS03035	COG3422	double-strand break repair
CPU03_RS03040	COG0826	peptidase U32
CPU03_RS03045	COG0583	DNA-binding transcription factor activity
CPU03_RS03050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPU03_RS03065	COG0351	phosphomethylpyrimidine kinase
CPU03_RS03070	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CPU03_RS03080	COG0640	Transcriptional regulator
CPU03_RS03085	COG0277	FAD linked oxidase domain protein
CPU03_RS03090	COG0720	synthase
CPU03_RS03095	COG2814	Major facilitator Superfamily
CPU03_RS03100	COG0602	queuosine metabolic process
CPU03_RS03110	COG0330	HflC and HflK could
CPU03_RS03115	COG1585	Membrane protein implicated in regulation of membrane protease activity
CPU03_RS03125	COG2217	Heavy metal translocating P-type atpase
CPU03_RS03130	COG3735	TraB family
CPU03_RS03140	COG2610	gluconate transmembrane transporter activity
CPU03_RS03150	COG0737	Belongs to the 5'-nucleotidase family
CPU03_RS03160	COG3188	usher protein
CPU03_RS03165	COG3121	Chaperone
CPU03_RS03175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPU03_RS03190	COG0326	Molecular chaperone. Has ATPase activity
CPU03_RS03215	COG2832	Protein of unknown function (DUF454)
CPU03_RS03225	COG2261	transglycosylase associated protein
CPU03_RS03235	COG3264	Mechanosensitive ion channel
CPU03_RS03235	COG1196	nuclear chromosome segregation
CPU03_RS03240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CPU03_RS03245	COG1309	transcriptional regulator
CPU03_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPU03_RS03255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPU03_RS03280	COG3695	enzyme binding
CPU03_RS03285	COG1946	Acyl-CoA thioesterase
CPU03_RS03290	COG0004	ammonium transporteR
CPU03_RS03295	COG0347	Belongs to the P(II) protein family
CPU03_RS03300	COG1522	sequence-specific DNA binding
CPU03_RS03305	COG0561	phosphatase activity
CPU03_RS03310	COG4533	DNA binding
CPU03_RS03320	COG1555	photosystem II stabilization
CPU03_RS03325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPU03_RS03330	COG0776	regulation of translation
CPU03_RS03335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CPU03_RS03355	COG0271	Belongs to the BolA IbaG family
CPU03_RS03360	COG3056	Lipoprotein
CPU03_RS03365	COG2223	nitrite transmembrane transporter activity
CPU03_RS03370	COG2814	Major facilitator Superfamily
CPU03_RS03380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CPU03_RS03385	COG0693	protein deglycase activity
CPU03_RS03410	COG1122	ATPase activity
CPU03_RS03425	COG0142	geranyltranstransferase activity
CPU03_RS03435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CPU03_RS03455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPU03_RS03455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPU03_RS03465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPU03_RS03470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPU03_RS03475	COG1862	Preprotein translocase
CPU03_RS03490	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CPU03_RS03495	COG0450	alkyl hydroperoxide reductase
CPU03_RS03500	COG0366	Alpha amylase catalytic
CPU03_RS03505	COG0668	transmembrane transport
CPU03_RS03515	COG1113	amino acid transport
CPU03_RS03520	COG1114	Component of the transport system for branched-chain amino acids
CPU03_RS03525	COG2200	EAL domain
CPU03_RS03540	COG5002	protein histidine kinase activity
CPU03_RS03540	COG3447	MASE1 domain protein
CPU03_RS03540	COG5001	Diguanylate cyclase
CPU03_RS03545	COG0443	Heat shock 70 kDa protein
CPU03_RS03555	COG0531	amino acid
CPU03_RS03575	COG1011	Hydrolase
CPU03_RS03585	COG1289	transmembrane transporter activity
CPU03_RS03590	COG1566	PFAM secretion protein HlyD family protein
CPU03_RS03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPU03_RS03615	COG1737	Transcriptional regulator
CPU03_RS03635	COG3842	ATPase activity
CPU03_RS03640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CPU03_RS03645	COG0725	ABC transporter, periplasmic molybdate-binding protein
CPU03_RS03660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPU03_RS03665	COG0583	DNA-binding transcription factor activity
CPU03_RS03675	COG0778	Nitroreductase
CPU03_RS03685	COG1275	C4-dicarboxylate transporter malic acid transport protein
CPU03_RS03740	COG1882	Formate acetyltransferase
CPU03_RS03755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPU03_RS03760	COG0583	DNA-binding transcription factor activity
CPU03_RS03775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CPU03_RS03780	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CPU03_RS03785	COG3708	Transcriptional regulator
CPU03_RS03785	COG2207	Transcriptional regulator
CPU03_RS03795	COG2211	Major facilitator Superfamily
CPU03_RS03885	COG0582	viral genome integration into host DNA
CPU03_RS03895	COG2130	NADP-dependent
CPU03_RS03905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CPU03_RS03915	COG1073	alpha beta
CPU03_RS03925	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPU03_RS03930	COG3040	lipid binding
CPU03_RS03935	COG3069	C4-dicarboxylate transmembrane transporter activity
CPU03_RS03940	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPU03_RS03955	COG0531	amino acid
CPU03_RS03960	COG0531	amino acid
CPU03_RS03965	COG1477	protein flavinylation
CPU03_RS03970	COG3034	peptidoglycan biosynthetic process
CPU03_RS03975	COG0121	glutamine amidotransferase
CPU03_RS03985	COG0347	Belongs to the P(II) protein family
CPU03_RS03990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPU03_RS03990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPU03_RS03995	COG2204	response regulator
CPU03_RS04005	COG2205	protein histidine kinase activity
CPU03_RS04010	COG0047	phosphoribosylformylglycinamidine synthase activity
CPU03_RS04010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPU03_RS04015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CPU03_RS04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPU03_RS04030	COG1454	alcohol dehydrogenase
CPU03_RS04035	COG0560	Phosphoserine phosphatase
CPU03_RS04040	COG1737	Transcriptional regulator
CPU03_RS04045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS04050	COG3015	lipoprotein NlpE involved in copper resistance
CPU03_RS04060	COG4681	YaeQ
CPU03_RS04070	COG4568	rho-dependent transcription termination
CPU03_RS04090	COG1982	Orn Lys Arg decarboxylase major
CPU03_RS04095	COG0531	amino acid
CPU03_RS04100	COG3710	Transcriptional regulator
CPU03_RS04105	COG0346	lactoylglutathione lyase activity
CPU03_RS04125	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPU03_RS04130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPU03_RS04135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPU03_RS04140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPU03_RS04145	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CPU03_RS04155	COG0750	zinc metalloprotease
CPU03_RS04160	COG0575	Belongs to the CDS family
CPU03_RS04165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPU03_RS04180	COG0528	UMP kinase activity
CPU03_RS04200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CPU03_RS04220	COG0564	pseudouridine synthase activity
CPU03_RS04225	COG3098	single-species biofilm formation
CPU03_RS04240	COG1611	Belongs to the LOG family
CPU03_RS04255	COG2363	Small membrane protein
CPU03_RS04260	COG0583	DNA-binding transcription factor activity
CPU03_RS04265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CPU03_RS04270	COG2166	iron-sulfur cluster assembly
CPU03_RS04275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPU03_RS04280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CPU03_RS04300	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPU03_RS04310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPU03_RS04315	COG1074	ATP-dependent DNA helicase activity
CPU03_RS04325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CPU03_RS04340	COG4795	General secretion pathway protein
CPU03_RS04355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CPU03_RS04365	COG2234	aminopeptidase activity
CPU03_RS04370	COG3416	Protein conserved in bacteria
CPU03_RS04380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPU03_RS04385	COG1643	Atp-dependent helicase
CPU03_RS04390	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CPU03_RS04415	COG0617	tRNA 3'-terminal CCA addition
CPU03_RS04420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPU03_RS04450	COG0726	polysaccharide deacetylase
CPU03_RS04465	COG3716	PTS system mannose fructose sorbose family IID component
CPU03_RS04470	COG3715	PTS system
CPU03_RS04475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPU03_RS04480	COG2222	sugar isomerase
CPU03_RS04485	COG1349	DNA-binding transcription factor activity
CPU03_RS04490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS04495	COG0842	Transport permease protein
CPU03_RS04500	COG1131	(ABC) transporter
CPU03_RS04505	COG0745	RESPONSE REGULATOR receiver
CPU03_RS04510	COG0288	reversible hydration of carbon dioxide
CPU03_RS04525	COG0697	spore germination
CPU03_RS04535	COG2979	Protein of unknown function (DUF533)
CPU03_RS04540	COG1049	propionate catabolic process, 2-methylcitrate cycle
CPU03_RS04550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPU03_RS04555	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPU03_RS04560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CPU03_RS04565	COG2186	Transcriptional regulator
CPU03_RS04575	COG3725	Membrane protein required for beta-lactamase induction
CPU03_RS04580	COG3023	N-Acetylmuramoyl-L-alanine amidase
CPU03_RS04585	COG4969	Belongs to the N-Me-Phe pilin family
CPU03_RS04590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPU03_RS04595	COG1459	type II secretion system
CPU03_RS04620	COG0494	nUDIX hydrolase
CPU03_RS04645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPU03_RS04650	COG0849	cell division
CPU03_RS04655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CPU03_RS04670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPU03_RS04675	COG0772	Belongs to the SEDS family
CPU03_RS04690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPU03_RS04695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPU03_RS04700	COG0768	penicillin binding
CPU03_RS04705	COG3116	cell division
CPU03_RS04730	COG0028	Belongs to the TPP enzyme family
CPU03_RS04735	COG1022	Amp-dependent synthetase and ligase
CPU03_RS04740	COG0583	DNA-binding transcription factor activity
CPU03_RS04750	COG0473	3-isopropylmalate dehydrogenase activity
CPU03_RS04765	COG0471	metal ion transport
CPU03_RS04775	COG4143	(ABC) transporter
CPU03_RS04780	COG1178	ABC-type Fe3 transport system permease component
CPU03_RS04785	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CPU03_RS04790	COG0417	DNA replication proofreading
CPU03_RS04795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CPU03_RS04800	COG0564	pseudouridine synthase activity
CPU03_RS04805	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CPU03_RS04810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CPU03_RS04820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CPU03_RS04825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CPU03_RS04840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CPU03_RS04850	COG2966	Psort location CytoplasmicMembrane, score
CPU03_RS04855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPU03_RS04860	COG0505	Belongs to the CarA family
CPU03_RS04870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CPU03_RS04875	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CPU03_RS04880	COG2080	2 iron, 2 sulfur cluster binding
CPU03_RS04885	COG1881	PFAM PEBP family protein
CPU03_RS04895	COG1047	Peptidyl-prolyl cis-trans
CPU03_RS04910	COG0196	riboflavin kinase activity
CPU03_RS04920	COG0268	Binds directly to 16S ribosomal RNA
CPU03_RS04925	COG0583	DNA-binding transcription factor activity
CPU03_RS04945	COG1584	GPR1 FUN34 yaaH family protein
CPU03_RS04955	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPU03_RS04965	COG1012	belongs to the aldehyde dehydrogenase family
CPU03_RS04975	COG1115	amino acid carrier protein
CPU03_RS04995	COG0460	homoserine dehydrogenase
CPU03_RS04995	COG0527	aspartate kinase activity
CPU03_RS05005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CPU03_RS05015	COG0745	RESPONSE REGULATOR receiver
CPU03_RS05025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPU03_RS05030	COG3118	belongs to the thioredoxin family
CPU03_RS05035	COG3148	PFAM DTW domain containing protein
CPU03_RS05040	COG1042	CoA-binding domain protein
CPU03_RS05040	COG0045	succinate-CoA ligase (ADP-forming) activity
CPU03_RS05040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPU03_RS05045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPU03_RS05075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CPU03_RS05090	COG1464	Belongs to the NlpA lipoprotein family
CPU03_RS05100	COG1720	tRNA m6t6A37 methyltransferase activity
CPU03_RS05110	COG3045	CreA protein
CPU03_RS05115	COG2207	Transcriptional regulator
CPU03_RS05115	COG3708	Transcriptional regulator
CPU03_RS05120	COG0406	alpha-ribazole phosphatase activity
CPU03_RS05140	COG0488	(ABC) transporter
CPU03_RS05145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPU03_RS05150	COG0560	Phosphoserine phosphatase
CPU03_RS05155	COG3726	membrane protein affecting hemolysin expression
CPU03_RS05165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPU03_RS05175	COG0792	nuclease activity
CPU03_RS05185	COG2823	Periplasmic or secreted lipoprotein
CPU03_RS05190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPU03_RS05195	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CPU03_RS05200	COG2198	Histidine kinase
CPU03_RS05200	COG0784	Response regulator, receiver
CPU03_RS05200	COG5002	protein histidine kinase activity
CPU03_RS05205	COG1242	4 iron, 4 sulfur cluster binding
CPU03_RS05215	COG0067	glutamate synthase
CPU03_RS05215	COG0070	glutamate synthase
CPU03_RS05215	COG0069	glutamate synthase activity
CPU03_RS05220	COG0493	'glutamate synthase
CPU03_RS05235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CPU03_RS05255	COG2969	positive regulation of protein catabolic process
CPU03_RS05260	COG0625	glutathione transferase activity
CPU03_RS05275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CPU03_RS05280	COG3105	Protein conserved in bacteria
CPU03_RS05285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPU03_RS05290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPU03_RS05295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPU03_RS05300	COG5007	Belongs to the BolA IbaG family
CPU03_RS05305	COG3113	response to antibiotic
CPU03_RS05310	COG2854	intermembrane phospholipid transfer
CPU03_RS05315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CPU03_RS05320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CPU03_RS05325	COG1127	ABC transporter
CPU03_RS05330	COG0530	calcium, potassium:sodium antiporter activity
CPU03_RS05335	COG0517	IMP dehydrogenase activity
CPU03_RS05335	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPU03_RS05340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CPU03_RS05345	COG3117	lipopolysaccharide transmembrane transporter activity
CPU03_RS05350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CPU03_RS05355	COG1137	ATPase activity
CPU03_RS05360	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CPU03_RS05380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS05385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPU03_RS05420	COG1328	CTP reductase activity
CPU03_RS05425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPU03_RS05430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPU03_RS05435	COG0084	hydrolase, TatD family'
CPU03_RS05440	COG4667	esterase of the alpha-beta hydrolase superfamily
CPU03_RS05450	COG0456	acetyltransferase
CPU03_RS05455	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CPU03_RS05460	COG2813	Specifically methylates the guanine in position
CPU03_RS05480	COG3384	dioxygenase
CPU03_RS05495	COG2960	long-chain fatty acid transporting porin activity
CPU03_RS05500	COG0531	amino acid
CPU03_RS05510	COG1560	Kdo2-lipid A biosynthetic process
CPU03_RS05515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CPU03_RS05520	COG3025	triphosphatase activity
CPU03_RS05525	COG1392	Phosphate transport regulator
CPU03_RS05530	COG0306	phosphate transporter
CPU03_RS05535	COG4991	sh3 domain protein
CPU03_RS05545	COG1968	undecaprenyl-diphosphatase activity
CPU03_RS05550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CPU03_RS05570	COG0358	DNA primase activity
CPU03_RS05575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPU03_RS05580	COG3663	DNA glycosylase
CPU03_RS05710	COG4695	Portal protein
CPU03_RS05785	COG4974	Belongs to the 'phage' integrase family
CPU03_RS05790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPU03_RS05795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPU03_RS05800	COG1882	Formate acetyltransferase
CPU03_RS05805	COG3111	PFAM Bacterial OB fold (BOF) protein
CPU03_RS05815	COG0642	Histidine kinase
CPU03_RS05820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPU03_RS05830	COG1451	nucleotide metabolic process
CPU03_RS05835	COG0673	inositol 2-dehydrogenase activity
CPU03_RS05840	COG0697	spore germination
CPU03_RS05845	COG0861	Integral membrane protein TerC family
CPU03_RS05860	COG2721	sulfolactate sulfo-lyase activity
CPU03_RS05865	COG0246	Mannitol dehydrogenase
CPU03_RS05875	COG2271	Major facilitator Superfamily
CPU03_RS05890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPU03_RS05900	COG0586	Pfam SNARE associated Golgi protein
CPU03_RS05910	COG4575	ribosome binding
CPU03_RS05915	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CPU03_RS05930	COG0602	queuosine metabolic process
CPU03_RS05935	COG0702	epimerase
CPU03_RS05945	COG2827	Endonuclease containing a URI domain
CPU03_RS05950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPU03_RS05955	COG3153	acetyltransferase
CPU03_RS05960	COG3154	lipid carrier protein
CPU03_RS05965	COG0826	peptidase U32
CPU03_RS05970	COG0826	peptidase U32
CPU03_RS05980	COG0814	amino acid
CPU03_RS05985	COG0513	Belongs to the DEAD box helicase family
CPU03_RS06005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPU03_RS06020	COG0195	Participates in both transcription termination and antitermination
CPU03_RS06040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPU03_RS06050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPU03_RS06065	COG1534	Rna-binding protein
CPU03_RS06075	COG2027	D-alanyl-D-alanine carboxypeptidase
CPU03_RS06080	COG0745	RESPONSE REGULATOR receiver
CPU03_RS06085	COG0642	Histidine kinase
CPU03_RS06090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPU03_RS06095	COG0697	spore germination
CPU03_RS06105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CPU03_RS06110	COG0142	geranyltranstransferase activity
CPU03_RS06115	COG3423	Transcriptional regulator
CPU03_RS06135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPU03_RS06140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CPU03_RS06145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CPU03_RS06150	COG2105	PFAM AIG2 family protein
CPU03_RS06165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPU03_RS06170	COG1253	flavin adenine dinucleotide binding
CPU03_RS06190	COG0545	Peptidyl-prolyl cis-trans isomerase
CPU03_RS06195	COG3061	Opacity-associated protein A
CPU03_RS06210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CPU03_RS06215	COG2965	DNA replication, synthesis of RNA primer
CPU03_RS06235	COG1073	alpha beta
CPU03_RS06240	COG3650	response to hydrogen peroxide
CPU03_RS06250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPU03_RS06255	COG0557	exoribonuclease II activity
CPU03_RS06260	COG1959	2 iron, 2 sulfur cluster binding
CPU03_RS06270	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CPU03_RS06280	COG0330	HflC and HflK could
CPU03_RS06285	COG0330	HflC and HflK could
CPU03_RS06290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPU03_RS06295	COG1923	regulation of RNA biosynthetic process
CPU03_RS06300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPU03_RS06315	COG0802	atpase or kinase
CPU03_RS06320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPU03_RS06320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPU03_RS06325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPU03_RS06360	COG1511	domain protein
CPU03_RS06360	COG3264	Mechanosensitive ion channel
CPU03_RS06370	COG1053	succinate dehydrogenase
CPU03_RS06375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPU03_RS06380	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CPU03_RS06405	COG1620	l-lactate permease
CPU03_RS06410	COG0247	lactate metabolic process
CPU03_RS06415	COG1139	Iron-sulfur cluster binding protein
CPU03_RS06420	COG1556	Lactate utilization protein
CPU03_RS06440	COG3030	protein affecting phage T7 exclusion by the F plasmid
CPU03_RS06450	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPU03_RS06460	COG4232	protein-disulfide reductase activity
CPU03_RS06465	COG1309	transcriptional regulator
CPU03_RS06480	COG3961	Belongs to the TPP enzyme family
CPU03_RS06485	COG2205	protein histidine kinase activity
CPU03_RS06485	COG2198	Histidine kinase
CPU03_RS06485	COG0784	Response regulator, receiver
CPU03_RS06490	COG1879	ABC-type sugar transport system periplasmic component
CPU03_RS06495	COG0745	RESPONSE REGULATOR receiver
CPU03_RS06500	COG3005	denitrification pathway
CPU03_RS06515	COG3781	membrane
CPU03_RS06520	COG3247	response to pH
CPU03_RS06525	COG1454	alcohol dehydrogenase
CPU03_RS06530	COG0235	Class ii aldolase
CPU03_RS06535	COG0738	Major facilitator superfamily
CPU03_RS06555	COG1349	DNA-binding transcription factor activity
CPU03_RS06560	COG5463	Belongs to the UPF0441 family
CPU03_RS06565	COG0754	glutathionylspermidine amidase activity
CPU03_RS06575	COG0531	amino acid
CPU03_RS06580	COG3091	SprT-like family
CPU03_RS06585	COG2356	endonuclease I
CPU03_RS06590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPU03_RS06595	COG0189	ligase activity
CPU03_RS06600	COG1678	Uncharacterized ACR, COG1678
CPU03_RS06610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPU03_RS06615	COG0762	integral membrane protein
CPU03_RS06630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPU03_RS06635	COG4166	transmembrane transport
CPU03_RS06650	COG3171	Protein conserved in bacteria
CPU03_RS06660	COG1194	a g-specific adenine glycosylase
CPU03_RS06680	COG0531	amino acid
CPU03_RS06685	COG1982	Orn Lys Arg decarboxylase major
CPU03_RS06700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CPU03_RS06705	COG0471	metal ion transport
CPU03_RS06710	COG2223	nitrite transmembrane transporter activity
CPU03_RS06715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CPU03_RS06720	COG1140	nitrate reductase beta subunit
CPU03_RS06725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CPU03_RS06730	COG2181	nitrate reductase activity
CPU03_RS06740	COG0840	transmembrane signaling receptor activity
CPU03_RS06755	COG2207	Transcriptional regulator
CPU03_RS06760	COG1979	alcohol dehydrogenase
CPU03_RS06785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPU03_RS06795	COG0735	belongs to the Fur family
CPU03_RS06800	COG0534	Mate efflux family protein
CPU03_RS06810	COG4565	transcriptional regulatory protein
CPU03_RS06815	COG3290	protein histidine kinase activity
CPU03_RS06820	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CPU03_RS06830	COG2301	Belongs to the HpcH HpaI aldolase family
CPU03_RS06835	COG3051	citrate lyase alpha subunit
CPU03_RS06850	COG0471	metal ion transport
CPU03_RS06855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CPU03_RS06865	COG2223	nitrite transmembrane transporter activity
CPU03_RS06875	COG3161	chorismate lyase activity
CPU03_RS06895	COG2182	Extracellular solute-binding protein
CPU03_RS06900	COG1175	transmembrane transport
CPU03_RS06905	COG3833	ABC-type maltose transport systems, permease component
CPU03_RS06925	COG0527	aspartate kinase activity
CPU03_RS06950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPU03_RS06960	COG3150	esterase
CPU03_RS06965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CPU03_RS06970	COG0494	nUDIX hydrolase
CPU03_RS06975	COG1538	Outer membrane efflux protein
CPU03_RS06980	COG1301	dicarboxylic acid transport
CPU03_RS06985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CPU03_RS06990	COG1584	GPR1 FUN34 yaaH family protein
CPU03_RS07020	COG0151	Belongs to the GarS family
CPU03_RS07040	COG1515	deoxyribonuclease V activity
CPU03_RS07060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPU03_RS07070	COG0222	ribosome binding
CPU03_RS07090	COG0250	Participates in transcription elongation, termination and antitermination
CPU03_RS07135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CPU03_RS07170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPU03_RS07175	COG1739	Uncharacterized protein family UPF0029
CPU03_RS07215	COG0805	protein transport
CPU03_RS07220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPU03_RS07225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPU03_RS07245	COG1322	Protein conserved in bacteria
CPU03_RS07250	COG0586	Pfam SNARE associated Golgi protein
CPU03_RS07255	COG1966	Carbon starvation protein
CPU03_RS07265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CPU03_RS07270	COG0583	DNA-binding transcription factor activity
CPU03_RS07295	COG2217	Heavy metal translocating P-type atpase
CPU03_RS07300	COG1609	Transcriptional regulator
CPU03_RS07305	COG3265	gluconokinase activity
CPU03_RS07310	COG2610	gluconate transmembrane transporter activity
CPU03_RS07325	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CPU03_RS07335	COG3180	Ammonia monooxygenase
CPU03_RS07340	COG0598	Magnesium transport protein CorA
CPU03_RS07345	COG0210	DNA helicase
CPU03_RS07350	COG1011	Hydrolase
CPU03_RS07360	COG3159	Protein conserved in bacteria
CPU03_RS07390	COG1587	Uroporphyrinogen-III synthase
CPU03_RS07395	COG2959	enzyme of heme biosynthesis
CPU03_RS07400	COG3071	HemY protein
CPU03_RS07425	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CPU03_RS07435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPU03_RS07440	COG2244	polysaccharide biosynthetic process
CPU03_RS07445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPU03_RS07450	COG0456	acetyltransferase
CPU03_RS07455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CPU03_RS07465	COG1088	dTDP-glucose 4,6-dehydratase activity
CPU03_RS07470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CPU03_RS07475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CPU03_RS07480	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CPU03_RS07485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPU03_RS07495	COG3118	belongs to the thioredoxin family
CPU03_RS07505	COG0248	Ppx GppA phosphatase
CPU03_RS07510	COG0210	DNA helicase
CPU03_RS07515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPU03_RS07545	COG3978	acetolactate synthase activity
CPU03_RS07560	COG2814	Major facilitator Superfamily
CPU03_RS07585	COG0859	PFAM glycosyl transferase family 9
CPU03_RS07590	COG0859	PFAM glycosyl transferase family 9
CPU03_RS07620	COG0859	PFAM glycosyl transferase family 9
CPU03_RS07630	COG0438	transferase activity, transferring glycosyl groups
CPU03_RS07635	COG1519	Transferase
CPU03_RS07665	COG2003	Belongs to the UPF0758 family
CPU03_RS07670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPU03_RS07675	COG0756	dUTP diphosphatase activity
CPU03_RS07695	COG1561	YicC-like family, N-terminal region
CPU03_RS07700	COG3085	chromosome segregation
CPU03_RS07705	COG0583	DNA-binding transcription factor activity
CPU03_RS07740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CPU03_RS07750	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CPU03_RS07775	COG1309	transcriptional regulator
CPU03_RS07780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPU03_RS07790	COG0678	peroxiredoxin activity
CPU03_RS07790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPU03_RS07855	COG1295	ribonuclease BN
CPU03_RS07860	COG1011	Hydrolase
CPU03_RS07865	COG1217	gtp-binding protein TYPA
CPU03_RS07885	COG2204	response regulator
CPU03_RS07915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPU03_RS07915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPU03_RS07920	COG0204	Acyl-transferase
CPU03_RS07925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPU03_RS07930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CPU03_RS07935	COG3084	Protein conserved in bacteria
CPU03_RS07940	COG0746	molybdenum cofactor guanylyltransferase activity
CPU03_RS07945	COG1763	Mo-molybdopterin cofactor biosynthetic process
CPU03_RS07985	COG2186	Transcriptional regulator
CPU03_RS07990	COG0477	Major facilitator Superfamily
CPU03_RS07995	COG1609	Transcriptional regulator
CPU03_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPU03_RS08005	COG1879	ABC-type sugar transport system periplasmic component
CPU03_RS08010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CPU03_RS08015	COG1129	ABC transporter
CPU03_RS08025	COG3158	transport of potassium into the cell
CPU03_RS08045	COG1522	sequence-specific DNA binding
CPU03_RS08050	COG0716	FMN binding
CPU03_RS08065	COG3312	ion transport
CPU03_RS08080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPU03_RS08125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CPU03_RS08130	COG0573	inorganic phosphate transmembrane transporter activity
CPU03_RS08135	COG0581	inorganic phosphate transmembrane transporter activity
CPU03_RS08150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPU03_RS08160	COG2252	PERMEase
CPU03_RS08170	COG0398	Pfam SNARE associated Golgi protein
CPU03_RS08175	COG2840	Smr protein MutS2
CPU03_RS08210	COG0592	DNA-directed DNA polymerase activity
CPU03_RS08220	COG0187	DNA topoisomerase II activity
CPU03_RS08225	COG0561	phosphatase activity
CPU03_RS08230	COG0823	Involved in the tonB-independent uptake of proteins
CPU03_RS08235	COG5645	(Lipo)protein
CPU03_RS08240	COG0071	Belongs to the small heat shock protein (HSP20) family
CPU03_RS08250	COG3977	Valine--pyruvate aminotransferase
CPU03_RS08270	COG2818	Glycosylase
CPU03_RS08280	COG2119	membrane
CPU03_RS08285	COG2885	chlorophyll binding
CPU03_RS08295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CPU03_RS08310	COG2982	Protein involved in outer membrane biogenesis
CPU03_RS08315	COG2233	PERMEase
CPU03_RS08320	COG0786	glutamate:sodium symporter activity
CPU03_RS08325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPU03_RS08330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPU03_RS08335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPU03_RS08345	COG0194	GDP metabolic process
CPU03_RS08350	COG2860	membrane
CPU03_RS08355	COG2861	carbohydrate metabolic process
CPU03_RS08360	COG4942	peptidase
CPU03_RS08370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPU03_RS08375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPU03_RS08390	COG1045	serine acetyltransferase
CPU03_RS08395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CPU03_RS08400	COG2205	protein histidine kinase activity
CPU03_RS08405	COG0745	RESPONSE REGULATOR receiver
CPU03_RS08410	COG3678	ATP-independent chaperone mediated protein folding
CPU03_RS08420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CPU03_RS08430	COG0149	triose-phosphate isomerase activity
CPU03_RS08440	COG3152	Membrane
CPU03_RS08455	COG2814	Major facilitator Superfamily
CPU03_RS08460	COG1494	fructose-1,6-bisphosphatase
CPU03_RS08470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CPU03_RS08485	COG1575	Belongs to the MenA family. Type 1 subfamily
CPU03_RS08495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CPU03_RS08500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPU03_RS08505	COG1609	Transcriptional regulator
CPU03_RS08510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPU03_RS08535	COG0626	cystathionine gamma-synthase activity
CPU03_RS08540	COG0527	aspartate kinase activity
CPU03_RS08540	COG0460	homoserine dehydrogenase
CPU03_RS08555	COG0477	Major facilitator Superfamily
CPU03_RS08575	COG1051	belongs to the nudix hydrolase family
CPU03_RS08590	COG2207	Transcriptional regulator
CPU03_RS08595	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CPU03_RS08600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPU03_RS08605	COG0840	transmembrane signaling receptor activity
CPU03_RS08620	COG2271	Major facilitator Superfamily
CPU03_RS08635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPU03_RS08640	COG0747	negative chemotaxis
CPU03_RS08645	COG0601	transmembrane transport
CPU03_RS08650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPU03_RS08655	COG0444	Belongs to the ABC transporter superfamily
CPU03_RS08660	COG4608	Belongs to the ABC transporter superfamily
CPU03_RS08685	COG1192	Involved in chromosome partitioning
CPU03_RS08695	COG1215	transferase activity, transferring glycosyl groups
CPU03_RS08700	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CPU03_RS08705	COG3118	belongs to the thioredoxin family
CPU03_RS08705	COG0457	Tetratricopeptide repeat
CPU03_RS08710	COG2200	EAL domain
CPU03_RS08710	COG2199	diguanylate cyclase activity
CPU03_RS08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPU03_RS08730	COG2200	EAL domain
CPU03_RS08735	COG2134	cdp-diacylglycerol pyrophosphatase
CPU03_RS08740	COG0583	DNA-binding transcription factor activity
CPU03_RS08750	COG1181	Belongs to the D-alanine--D-alanine ligase family
CPU03_RS08765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPU03_RS08770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CPU03_RS08780	COG0339	signal peptide processing
CPU03_RS08790	COG0517	IMP dehydrogenase activity
CPU03_RS08790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPU03_RS08795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPU03_RS08800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CPU03_RS08805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CPU03_RS08810	COG1129	ABC transporter
CPU03_RS08820	COG0745	RESPONSE REGULATOR receiver
CPU03_RS08825	COG5002	protein histidine kinase activity
CPU03_RS08840	COG0589	response to stress
CPU03_RS08850	COG0733	neurotransmitter:sodium symporter activity
CPU03_RS08855	COG0306	phosphate transporter
CPU03_RS08865	COG3275	phosphorelay sensor kinase activity
CPU03_RS08870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPU03_RS08875	COG2267	carboxylic ester hydrolase activity
CPU03_RS08880	COG0561	phosphatase activity
CPU03_RS08890	COG2864	formate dehydrogenase
CPU03_RS08895	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS08905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CPU03_RS08910	COG2258	MOSC domain
CPU03_RS08915	COG3714	YhhN family
CPU03_RS08930	COG3776	membrane
CPU03_RS08935	COG0742	ribosomal rna small subunit methyltransferase
CPU03_RS08945	COG2884	Cell division ATP-binding protein ftsE
CPU03_RS08950	COG2177	Part of the ABC transporter FtsEX involved in
CPU03_RS08960	COG3835	regulator
CPU03_RS08965	COG2610	gluconate transmembrane transporter activity
CPU03_RS08970	COG1929	Belongs to the glycerate kinase type-1 family
CPU03_RS08975	COG0456	acetyltransferase
CPU03_RS08990	COG0395	ABC-type sugar transport system, permease component
CPU03_RS09000	COG0584	glycerophosphoryl diester phosphodiesterase
CPU03_RS09015	COG0705	Rhomboid family
CPU03_RS09020	COG1349	DNA-binding transcription factor activity
CPU03_RS09025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPU03_RS09030	COG0058	SHG alpha-glucan phosphorylase activity
CPU03_RS09040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CPU03_RS09045	COG1523	belongs to the glycosyl hydrolase 13 family
CPU03_RS09050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CPU03_RS09055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CPU03_RS09060	COG1640	4-alpha-glucanotransferase
CPU03_RS09065	COG0058	SHG alpha-glucan phosphorylase activity
CPU03_RS09070	COG2909	trisaccharide binding
CPU03_RS09080	COG0429	hydrolase of the alpha beta-hydrolase fold
CPU03_RS09090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPU03_RS09095	COG1289	transmembrane transporter activity
CPU03_RS09120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CPU03_RS09125	COG1918	ferrous iron import across plasma membrane
CPU03_RS09135	COG2183	response to ionizing radiation
CPU03_RS09140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPU03_RS09165	COG0484	heat shock protein binding
CPU03_RS09175	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS09185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CPU03_RS09190	COG1011	Hydrolase
CPU03_RS09200	COG0494	nUDIX hydrolase
CPU03_RS09205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CPU03_RS09225	COG4796	Type ii and iii secretion system protein
CPU03_RS09230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPU03_RS09250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPU03_RS09255	COG0546	phosphoglycolate phosphatase activity
CPU03_RS09260	COG0180	Tryptophanyl-tRNA synthetase
CPU03_RS09270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CPU03_RS09275	COG0402	S-adenosylhomocysteine deaminase activity
CPU03_RS09285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPU03_RS09300	COG0488	(ABC) transporter
CPU03_RS09305	COG2249	NAD(P)H dehydrogenase (quinone) activity
CPU03_RS09315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CPU03_RS09320	COG1047	Peptidyl-prolyl cis-trans
CPU03_RS09330	COG0545	Peptidyl-prolyl cis-trans isomerase
CPU03_RS09335	COG2964	Protein conserved in bacteria
CPU03_RS09350	COG2168	tRNA wobble position uridine thiolation
CPU03_RS09375	COG0051	transcription antitermination factor activity, RNA binding
CPU03_RS09380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPU03_RS09405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CPU03_RS09480	COG0201	protein transport
CPU03_RS09485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPU03_RS09490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPU03_RS09520	COG0789	Transcriptional regulator
CPU03_RS09525	COG1970	mechanosensitive ion channel activity
CPU03_RS09530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPU03_RS09535	COG0569	domain protein
CPU03_RS09540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPU03_RS09540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPU03_RS09555	COG0758	DNA mediated transformation
CPU03_RS09560	COG2922	Belongs to the Smg family
CPU03_RS09565	COG0551	DNA topoisomerase type I activity
CPU03_RS09585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CPU03_RS09655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CPU03_RS09670	COG0656	L-ascorbic acid biosynthetic process
CPU03_RS09675	COG1448	Aminotransferase
CPU03_RS09680	COG0432	Pfam Uncharacterised protein family UPF0047
CPU03_RS09685	COG2315	Protein conserved in bacteria
CPU03_RS09690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CPU03_RS09705	COG3829	transcription factor binding
CPU03_RS09710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CPU03_RS09715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPU03_RS09720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPU03_RS09730	COG0549	Belongs to the carbamate kinase family
CPU03_RS09735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CPU03_RS09735	COG3608	succinylglutamate desuccinylase aspartoacylase
CPU03_RS09740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPU03_RS09745	COG2068	MobA-Related Protein
CPU03_RS09750	COG0493	'glutamate synthase
CPU03_RS09750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS09755	COG0402	S-adenosylhomocysteine deaminase activity
CPU03_RS09760	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CPU03_RS09765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CPU03_RS09765	COG2080	2 iron, 2 sulfur cluster binding
CPU03_RS09770	COG2233	PERMEase
CPU03_RS09775	COG0402	S-adenosylhomocysteine deaminase activity
CPU03_RS09780	COG2252	PERMEase
CPU03_RS09785	COG0025	NhaP-type Na H and K H
CPU03_RS09790	COG0583	DNA-binding transcription factor activity
CPU03_RS09800	COG1346	cytolysis
CPU03_RS09840	COG4145	pantothenate transmembrane transporter activity
CPU03_RS09845	COG3924	membrane
CPU03_RS09850	COG0439	Biotin carboxylase
CPU03_RS09855	COG0511	ligase activity, forming carbon-carbon bonds
CPU03_RS09870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CPU03_RS09875	COG0604	alcohol dehydrogenase
CPU03_RS09880	COG2199	diguanylate cyclase activity
CPU03_RS09880	COG2200	EAL domain
CPU03_RS09885	COG1077	Cell shape determining protein MreB Mrl
CPU03_RS09890	COG1792	Involved in formation and maintenance of cell shape
CPU03_RS09895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CPU03_RS09910	COG3164	Protein of unknown function
CPU03_RS09915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPU03_RS09920	COG0312	modulator of DNA gyrase
CPU03_RS09925	COG0583	DNA-binding transcription factor activity
CPU03_RS09935	COG1566	PFAM secretion protein HlyD family protein
CPU03_RS09945	COG0540	Belongs to the ATCase OTCase family
CPU03_RS09960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CPU03_RS09965	COG1012	belongs to the aldehyde dehydrogenase family
CPU03_RS09970	COG3276	selenocysteine insertion sequence binding
CPU03_RS09980	COG0625	glutathione transferase activity
CPU03_RS09985	COG0584	glycerophosphoryl diester phosphodiesterase
CPU03_RS09990	COG2271	Major facilitator Superfamily
CPU03_RS09995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPU03_RS10005	COG0247	lactate metabolic process
CPU03_RS10010	COG2731	YhcH YjgK YiaL family protein
CPU03_RS10025	COG0456	acetyltransferase
CPU03_RS10030	COG1116	anion transmembrane transporter activity
CPU03_RS10035	COG4176	ABC-type proline glycine betaine transport system permease component
CPU03_RS10045	COG2927	DNA polymerase III (CHI subunit)
CPU03_RS10055	COG0795	lipopolysaccharide-transporting ATPase activity
CPU03_RS10060	COG0795	lipopolysaccharide-transporting ATPase activity
CPU03_RS10065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CPU03_RS10070	COG1376	ErfK ybiS ycfS ynhG family protein
CPU03_RS10145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CPU03_RS10160	COG1447	Phosphotransferase system cellobiose-specific component IIA
CPU03_RS10175	COG4974	Belongs to the 'phage' integrase family
CPU03_RS10180	COG0582	viral genome integration into host DNA
CPU03_RS10205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPU03_RS10225	COG3037	sugar-specific permease SgaT UlaA
CPU03_RS10235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS10240	COG1609	Transcriptional regulator
CPU03_RS10245	COG2271	Major facilitator Superfamily
CPU03_RS10255	COG2271	Major facilitator Superfamily
CPU03_RS10260	COG1609	Transcriptional regulator
CPU03_RS10270	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPU03_RS10280	COG1129	ABC transporter
CPU03_RS10285	COG1172	Belongs to the binding-protein-dependent transport system permease family
CPU03_RS10290	COG1486	melibiose metabolic process
CPU03_RS10295	COG3275	phosphorelay sensor kinase activity
CPU03_RS10300	COG3279	Response regulator of the LytR AlgR family
CPU03_RS10305	COG2223	nitrite transmembrane transporter activity
CPU03_RS10315	COG1982	Orn Lys Arg decarboxylase major
CPU03_RS10320	COG0531	amino acid
CPU03_RS10325	COG1982	Orn Lys Arg decarboxylase major
CPU03_RS10330	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CPU03_RS10340	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CPU03_RS10345	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CPU03_RS10350	COG1999	signal sequence binding
CPU03_RS10355	COG1773	rubredoxin
CPU03_RS10365	COG1271	oxidase subunit
CPU03_RS10370	COG1294	oxidase, subunit
CPU03_RS10385	COG0583	DNA-binding transcription factor activity
CPU03_RS10390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CPU03_RS10400	COG2211	Major facilitator Superfamily
CPU03_RS10405	COG2211	Major facilitator Superfamily
CPU03_RS10430	COG3069	C4-dicarboxylate transmembrane transporter activity
CPU03_RS10435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CPU03_RS10440	COG0583	DNA-binding transcription factor activity
CPU03_RS10445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPU03_RS10465	COG2723	6-phospho-beta-galactosidase activity
CPU03_RS10475	COG2732	(Barnase) inhibitor
CPU03_RS10485	COG2916	Histone family protein nucleoid-structuring protein H-NS
CPU03_RS10490	COG0312	modulator of DNA gyrase
CPU03_RS10495	COG2814	Major facilitator Superfamily
CPU03_RS10510	COG1166	arginine decarboxylase activity
CPU03_RS10520	COG3119	arylsulfatase activity
CPU03_RS10525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPU03_RS10535	COG0126	phosphoglycerate kinase activity
CPU03_RS10550	COG1279	arginine transmembrane transporter activity
CPU03_RS10570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPU03_RS10575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CPU03_RS10595	COG0006	proline dipeptidase activity
CPU03_RS10600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPU03_RS10605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPU03_RS10625	COG1115	amino acid carrier protein
CPU03_RS10630	COG1272	protein, Hemolysin III
CPU03_RS10635	COG3248	Nucleoside-binding outer membrane protein
CPU03_RS10640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPU03_RS10650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CPU03_RS10660	COG0716	FMN binding
CPU03_RS10665	COG4974	Belongs to the 'phage' integrase family
CPU03_RS10675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CPU03_RS10750	COG3133	Outer membrane lipoprotein
CPU03_RS10755	COG1560	Kdo2-lipid A biosynthetic process
CPU03_RS10780	COG3119	arylsulfatase activity
CPU03_RS10785	COG0583	DNA-binding transcription factor activity
CPU03_RS10805	COG0309	Hydrogenase expression formation protein (HypE)
CPU03_RS10810	COG0409	Hydrogenase expression formation protein
CPU03_RS10815	COG0298	carbon dioxide binding
CPU03_RS10820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CPU03_RS10825	COG0375	protein maturation
CPU03_RS10830	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CPU03_RS10835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS10845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CPU03_RS10855	COG3260	NADH ubiquinone oxidoreductase 20
CPU03_RS10860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CPU03_RS10865	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CPU03_RS10865	COG3261	NADH dehydrogenase
CPU03_RS10870	COG0650	Formate hydrogenlyase subunit 4
CPU03_RS10875	COG0651	ATP synthesis coupled electron transport
CPU03_RS10880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS10885	COG1609	Transcriptional regulator
CPU03_RS10890	COG1609	Transcriptional regulator
CPU03_RS10895	COG0318	PFAM AMP-dependent synthetase and ligase
CPU03_RS10895	COG0204	Acyl-transferase
CPU03_RS10905	COG1785	Belongs to the alkaline phosphatase family
CPU03_RS10915	COG0861	Integral membrane protein TerC family
CPU03_RS10920	COG3066	DNA modification
CPU03_RS10940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CPU03_RS10960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CPU03_RS10965	COG4942	peptidase
CPU03_RS10965	COG1388	LysM domain
CPU03_RS10990	COG0840	transmembrane signaling receptor activity
CPU03_RS10995	COG0076	glutamate decarboxylase activity
CPU03_RS11000	COG0531	amino acid
CPU03_RS11010	COG0531	amino acid
CPU03_RS11030	COG2137	regulation of response to DNA damage stimulus
CPU03_RS11040	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CPU03_RS11070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPU03_RS11075	COG1238	metal cluster binding
CPU03_RS11090	COG4536	flavin adenine dinucleotide binding
CPU03_RS11095	COG4137	Cytochrome C assembly protein
CPU03_RS11100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPU03_RS11120	COG0335	large ribosomal subunit rRNA binding
CPU03_RS11130	COG3137	Salt-induced outer membrane protein
CPU03_RS11135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPU03_RS11150	COG3279	Response regulator of the LytR AlgR family
CPU03_RS11155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CPU03_RS11160	COG0287	Prephenate dehydrogenase
CPU03_RS11160	COG1605	Chorismate mutase
CPU03_RS11165	COG1605	Chorismate mutase
CPU03_RS11165	COG0077	Prephenate dehydratase
CPU03_RS11170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPU03_RS11175	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPU03_RS11190	COG1496	oxidoreductase activity
CPU03_RS11195	COG0542	response to heat
CPU03_RS11225	COG3021	interspecies interaction between organisms
CPU03_RS11230	COG1388	LysM domain
CPU03_RS11230	COG0741	lytic transglycosylase activity
CPU03_RS11240	COG2226	methyltransferase
CPU03_RS11260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CPU03_RS11260	COG1017	nitric oxide dioxygenase activity
CPU03_RS11275	COG0483	inositol monophosphate 1-phosphatase activity
CPU03_RS11280	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CPU03_RS11295	COG0822	iron-sulfur transferase activity
CPU03_RS11315	COG0633	Ferredoxin
CPU03_RS11320	COG2975	iron-sulfur cluster assembly
CPU03_RS11325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPU03_RS11355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CPU03_RS11365	COG2976	Protein conserved in bacteria
CPU03_RS11370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPU03_RS11385	COG1645	bacterial-type flagellum-dependent swarming motility
CPU03_RS11395	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CPU03_RS11400	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS11405	COG3301	Polysulphide reductase, NrfD
CPU03_RS11410	COG1138	Cytochrome C-type biogenesis protein
CPU03_RS11415	COG3088	subunit of a heme lyase
CPU03_RS11430	COG0517	IMP dehydrogenase activity
CPU03_RS11430	COG0516	GMP reductase activity
CPU03_RS11500	COG2860	membrane
CPU03_RS11515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CPU03_RS11520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPU03_RS11525	COG3842	ATPase activity
CPU03_RS11535	COG1840	ABC-type Fe3 transport system, periplasmic component
CPU03_RS11540	COG2814	Major facilitator Superfamily
CPU03_RS11545	COG1566	PFAM secretion protein HlyD family protein
CPU03_RS11550	COG1846	Transcriptional regulator
CPU03_RS11565	COG0583	DNA-binding transcription factor activity
CPU03_RS11575	COG2203	Gaf domain
CPU03_RS11575	COG3706	GGDEF domain
CPU03_RS11575	COG5001	Diguanylate cyclase
CPU03_RS11575	COG4251	negative regulation of phosphorylation
CPU03_RS11580	COG0814	amino acid
CPU03_RS11600	COG1953	Uracil, thiamine, allantoin
CPU03_RS11660	COG0582	viral genome integration into host DNA
CPU03_RS11675	COG2867	negative regulation of translational initiation
CPU03_RS11685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPU03_RS11690	COG0497	DNA recombination
CPU03_RS11700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPU03_RS11705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPU03_RS11715	COG0513	Belongs to the DEAD box helicase family
CPU03_RS11745	COG3086	response to oxidative stress
CPU03_RS11755	COG0681	Belongs to the peptidase S26 family
CPU03_RS11765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CPU03_RS11795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPU03_RS11800	COG3956	TIGRFAM MazG family protein
CPU03_RS11815	COG2841	Protein conserved in bacteria
CPU03_RS11825	COG0700	Nucleoside recognition
CPU03_RS11830	COG3366	ferrous iron transmembrane transporter activity
CPU03_RS11835	COG3118	belongs to the thioredoxin family
CPU03_RS11840	COG0300	oxidoreductase activity
CPU03_RS11845	COG2755	lipolytic protein G-D-S-L family
CPU03_RS11850	COG4181	ATPase activity
CPU03_RS11855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CPU03_RS11860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CPU03_RS11865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPU03_RS11870	COG3706	GGDEF domain
CPU03_RS11880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPU03_RS11890	COG2501	S4 domain
CPU03_RS11960	COG0754	glutathionylspermidine amidase activity
CPU03_RS11985	COG0058	SHG alpha-glucan phosphorylase activity
CPU03_RS11990	COG3158	transport of potassium into the cell
CPU03_RS11995	COG3969	phosphoadenosine phosphosulfate
CPU03_RS12000	COG1475	DNA binding
CPU03_RS12020	COG0157	Belongs to the NadC ModD family
CPU03_RS12025	COG2226	methyltransferase
CPU03_RS12090	COG0657	acetylesterase activity
CPU03_RS12095	COG2271	Major facilitator Superfamily
CPU03_RS12100	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CPU03_RS12105	COG0644	oxidoreductase
CPU03_RS12140	COG1024	Enoyl-CoA hydratase
CPU03_RS12160	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CPU03_RS12165	COG4989	oxidoreductase activity
CPU03_RS12195	COG1686	Belongs to the peptidase S11 family
CPU03_RS12200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPU03_RS12205	COG0772	Belongs to the SEDS family
CPU03_RS12210	COG0768	penicillin binding
CPU03_RS12220	COG0799	negative regulation of ribosome biogenesis
CPU03_RS12230	COG1466	dna polymerase III delta subunit
CPU03_RS12235	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CPU03_RS12245	COG2888	peptidyl-tyrosine sulfation
CPU03_RS12260	COG1126	abc transporter atp-binding protein
CPU03_RS12265	COG0765	amino acid transport
CPU03_RS12270	COG0765	amino acid transport
CPU03_RS12280	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CPU03_RS12285	COG0686	Belongs to the AlaDH PNT family
CPU03_RS12290	COG4535	Mg2 and Co2 transporter CorC
CPU03_RS12300	COG1702	phosphate starvation-inducible protein PhoH
CPU03_RS12310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPU03_RS12350	COG0367	asparagine synthase
CPU03_RS12355	COG0647	UMP catabolic process
CPU03_RS12360	COG1846	Transcriptional regulator
CPU03_RS12360	COG1940	carbohydrate kinase activity
CPU03_RS12365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPU03_RS12375	COG2190	(PTS) system
CPU03_RS12375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPU03_RS12375	COG1263	PTS System
CPU03_RS12400	COG0735	belongs to the Fur family
CPU03_RS12405	COG0716	FMN binding
CPU03_RS12415	COG0596	Alpha beta hydrolase
CPU03_RS12420	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CPU03_RS12425	COG0033	Phosphoglucomutase
CPU03_RS12430	COG0745	RESPONSE REGULATOR receiver
CPU03_RS12435	COG2205	protein histidine kinase activity
CPU03_RS12440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CPU03_RS12465	COG3272	Protein of unknown function (DUF1722)
CPU03_RS12475	COG5212	phosphodiesterase
CPU03_RS12480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPU03_RS12495	COG2824	Alkylphosphonate utilization operon protein PhnA
CPU03_RS12515	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CPU03_RS12520	COG1053	succinate dehydrogenase
CPU03_RS12525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPU03_RS12530	COG0567	Dehydrogenase, E1 component
CPU03_RS12535	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPU03_RS12545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CPU03_RS12550	COG1271	oxidase subunit
CPU03_RS12555	COG1294	oxidase, subunit
CPU03_RS12560	COG4890	Cyd operon protein YbgT
CPU03_RS12565	COG3790	cyd operon protein YbgE
CPU03_RS12570	COG0824	Thioesterase
CPU03_RS12575	COG0811	peptide transport
CPU03_RS12580	COG0848	biopolymer transport protein
CPU03_RS12585	COG3064	Membrane
CPU03_RS12585	COG3064	Membrane
CPU03_RS12595	COG2885	chlorophyll binding
CPU03_RS12600	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CPU03_RS12635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CPU03_RS12645	COG0471	metal ion transport
CPU03_RS12650	COG2017	converts alpha-aldose to the beta-anomer
CPU03_RS12655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CPU03_RS12660	COG1085	galactose-1-phosphate uridylyltransferase
CPU03_RS12665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CPU03_RS12675	COG2005	Transcriptional regulator
CPU03_RS12675	COG3585	molybdate ion transport
CPU03_RS12685	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CPU03_RS12690	COG0725	ABC transporter, periplasmic molybdate-binding protein
CPU03_RS12695	COG4149	molybdate abc transporter
CPU03_RS12705	COG0561	phosphatase activity
CPU03_RS12720	COG0156	8-amino-7-oxononanoate synthase activity
CPU03_RS12740	COG4628	conserved protein (DUF2132)
CPU03_RS12745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPU03_RS12760	COG1686	Belongs to the peptidase S11 family
CPU03_RS12765	COG2354	Protein conserved in bacteria
CPU03_RS12770	COG1349	DNA-binding transcription factor activity
CPU03_RS12780	COG2222	sugar isomerase
CPU03_RS12785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPU03_RS12790	COG3715	PTS system
CPU03_RS12795	COG3716	PTS system mannose fructose sorbose family IID component
CPU03_RS12805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPU03_RS12810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CPU03_RS12815	COG0641	radical SAM
CPU03_RS12820	COG3119	arylsulfatase activity
CPU03_RS12850	COG0840	transmembrane signaling receptor activity
CPU03_RS12855	COG0583	DNA-binding transcription factor activity
CPU03_RS12860	COG0488	(ABC) transporter
CPU03_RS12890	COG0523	cobalamin synthesis protein
CPU03_RS12895	COG2879	small protein
CPU03_RS12900	COG1966	Carbon starvation protein
CPU03_RS12910	COG2951	lytic endotransglycosylase activity
CPU03_RS12915	COG0640	Transcriptional regulator
CPU03_RS12920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPU03_RS12925	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPU03_RS12925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CPU03_RS12925	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPU03_RS12925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPU03_RS12930	COG0493	'glutamate synthase
CPU03_RS12945	COG2188	Transcriptional regulator
CPU03_RS12980	COG1278	Cold shock
CPU03_RS12995	COG1566	PFAM secretion protein HlyD family protein
CPU03_RS13010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPU03_RS13015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPU03_RS13020	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPU03_RS13025	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CPU03_RS13030	COG1138	Cytochrome C-type biogenesis protein
CPU03_RS13035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPU03_RS13040	COG4235	cytochrome complex assembly
CPU03_RS13040	COG3088	subunit of a heme lyase
CPU03_RS13045	COG4235	cytochrome complex assembly
CPU03_RS13045	COG3088	subunit of a heme lyase
CPU03_RS13055	COG2067	long-chain fatty acid transport protein
CPU03_RS13060	COG3691	Protein conserved in bacteria
CPU03_RS13065	COG2062	phosphohistidine phosphatase, SixA
CPU03_RS13075	COG2890	protein-(glutamine-N5) methyltransferase activity
CPU03_RS13090	COG0730	response to heat
CPU03_RS13095	COG3101	peptidyl-lysine hydroxylation
CPU03_RS13105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CPU03_RS13105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CPU03_RS13110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPU03_RS13145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPU03_RS13155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPU03_RS13165	COG0586	Pfam SNARE associated Golgi protein
CPU03_RS13170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPU03_RS13175	COG0285	dihydrofolate synthase activity
CPU03_RS13180	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CPU03_RS13185	COG1286	toxin biosynthetic process
CPU03_RS13190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPU03_RS13195	COG0163	prenyltransferase activity
CPU03_RS13200	COG1028	Short-chain dehydrogenase reductase Sdr
CPU03_RS13205	COG1090	epimerase
CPU03_RS13210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CPU03_RS13215	COG0625	glutathione transferase activity
CPU03_RS13220	COG0625	glutathione transferase activity
CPU03_RS13225	COG0622	Phosphoesterase
CPU03_RS13230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CPU03_RS13235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPU03_RS13240	COG0280	phosphate acetyltransferase
CPU03_RS13240	COG0857	belongs to the CobB CobQ family
CPU03_RS13245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CPU03_RS13260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPU03_RS13265	COG0490	domain, Protein
CPU03_RS13265	COG0471	metal ion transport
CPU03_RS13275	COG0436	Aminotransferase
CPU03_RS13280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CPU03_RS13285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CPU03_RS13290	COG2897	thiosulfate sulfurtransferase activity
CPU03_RS13295	COG0398	Pfam SNARE associated Golgi protein
CPU03_RS13300	COG0583	DNA-binding transcription factor activity
CPU03_RS13345	COG0839	Belongs to the complex I subunit 6 family
CPU03_RS13355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPU03_RS13360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CPU03_RS13365	COG1007	ATP synthesis coupled electron transport
CPU03_RS13370	COG1472	Belongs to the glycosyl hydrolase 3 family
CPU03_RS13375	COG3038	cytochrome b561
CPU03_RS13380	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CPU03_RS13385	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS13390	COG5557	Pfam Polysulphide reductase, NrfD
CPU03_RS13395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CPU03_RS13400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CPU03_RS13405	COG1773	rubredoxin
CPU03_RS13420	COG1169	isochorismate synthase
CPU03_RS13435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CPU03_RS13455	COG0180	Tryptophanyl-tRNA synthetase
CPU03_RS13460	COG0814	amino acid
CPU03_RS13485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CPU03_RS13500	COG0670	Belongs to the BI1 family
CPU03_RS13505	COG0243	molybdopterin cofactor binding
CPU03_RS13510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CPU03_RS13535	COG2205	protein histidine kinase activity
CPU03_RS13535	COG0784	Response regulator, receiver
CPU03_RS13545	COG0642	Histidine kinase
CPU03_RS13545	COG2198	Histidine kinase
CPU03_RS13550	COG0842	Transport permease protein
CPU03_RS13555	COG0842	Transport permease protein
CPU03_RS13560	COG1131	(ABC) transporter
CPU03_RS13565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPU03_RS13570	COG1309	transcriptional regulator
CPU03_RS13575	COG0513	Belongs to the DEAD box helicase family
CPU03_RS13580	COG3708	Transcriptional regulator
CPU03_RS13580	COG2207	Transcriptional regulator
CPU03_RS13585	COG1309	transcriptional regulator
CPU03_RS13590	COG1227	inorganic diphosphatase activity
CPU03_RS13595	COG0589	response to stress
CPU03_RS13600	COG0148	phosphopyruvate hydratase activity
CPU03_RS13640	COG1061	Type III restriction enzyme res subunit
CPU03_RS13650	COG1187	pseudouridine synthase activity
CPU03_RS13655	COG2814	Major facilitator Superfamily
CPU03_RS13665	COG4166	transmembrane transport
CPU03_RS13675	COG1126	abc transporter atp-binding protein
CPU03_RS13680	COG0765	amino acid transport
CPU03_RS13685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPU03_RS13695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS13695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS13700	COG1105	Belongs to the carbohydrate kinase PfkB family
CPU03_RS13705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPU03_RS13705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CPU03_RS13705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPU03_RS13710	COG1113	amino acid transport
CPU03_RS13715	COG0791	NLP P60 protein
CPU03_RS13720	COG0523	cobalamin synthesis protein
CPU03_RS13730	COG2186	Transcriptional regulator
CPU03_RS13735	COG2200	EAL domain
CPU03_RS13735	COG2771	luxR family
CPU03_RS13740	COG0840	transmembrane signaling receptor activity
CPU03_RS13745	COG0246	Mannitol dehydrogenase
CPU03_RS13775	COG0243	molybdopterin cofactor binding
CPU03_RS13780	COG3005	denitrification pathway
CPU03_RS13805	COG0131	Imidazoleglycerol-phosphate dehydratase
CPU03_RS13805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CPU03_RS13825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPU03_RS13830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPU03_RS13835	COG2207	Transcriptional regulator
CPU03_RS13840	COG1881	PFAM PEBP family protein
CPU03_RS13850	COG1686	Belongs to the peptidase S11 family
CPU03_RS13855	COG1760	l-serine dehydratase
CPU03_RS13860	COG0814	amino acid
CPU03_RS13865	COG1349	DNA-binding transcription factor activity
CPU03_RS13870	COG0671	phosphoesterase, PA-phosphatase related
CPU03_RS13875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPU03_RS13880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CPU03_RS13885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CPU03_RS13890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPU03_RS13895	COG1609	Transcriptional regulator
CPU03_RS13920	COG0778	Nitroreductase
CPU03_RS13945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPU03_RS13950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPU03_RS13955	COG4160	amino acid transport
CPU03_RS13960	COG4215	(ABC) transporter
CPU03_RS13965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPU03_RS13970	COG1126	abc transporter atp-binding protein
CPU03_RS13980	COG3188	usher protein
CPU03_RS13985	COG3121	Chaperone
CPU03_RS13995	COG2197	response regulator
CPU03_RS14000	COG3023	N-Acetylmuramoyl-L-alanine amidase
CPU03_RS14005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPU03_RS14010	COG0702	epimerase
CPU03_RS14015	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CPU03_RS14030	COG3121	Chaperone
CPU03_RS14060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CPU03_RS14070	COG2431	L-lysine efflux transmembrane transporter activity
CPU03_RS14075	COG3593	DNA synthesis involved in DNA repair
CPU03_RS14085	COG2990	Protein conserved in bacteria
CPU03_RS14090	COG1278	Cold shock
CPU03_RS14100	COG0542	response to heat
CPU03_RS14105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CPU03_RS14115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CPU03_RS14120	COG4988	ABC transporter
CPU03_RS14125	COG0492	ferredoxin-NADP+ reductase activity
CPU03_RS14130	COG1522	sequence-specific DNA binding
CPU03_RS14135	COG3107	peptidoglycan biosynthetic process
CPU03_RS14135	COG1674	ftsk spoiiie
CPU03_RS14145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPU03_RS14155	COG0243	molybdopterin cofactor binding
CPU03_RS14160	COG0437	4 iron, 4 sulfur cluster binding
CPU03_RS14165	COG3302	dmso reductase anchor subunit
CPU03_RS14175	COG2221	Nitrite and sulphite reductase 4Fe-4S
CPU03_RS14175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS14195	COG0785	Cytochrome C biogenesis protein
CPU03_RS14210	COG1309	transcriptional regulator
CPU03_RS14215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPU03_RS14220	COG1882	Formate acetyltransferase
CPU03_RS14225	COG2116	formate transmembrane transporter activity
CPU03_RS14230	COG1944	ATP diphosphatase activity
CPU03_RS14235	COG0252	asparaginase activity
CPU03_RS14255	COG0539	negative regulation of cytoplasmic translation
CPU03_RS14270	COG2333	competence protein COMEC
CPU03_RS14270	COG0658	competence protein
CPU03_RS14305	COG3173	Aminoglycoside phosphotransferase
CPU03_RS14310	COG2233	PERMEase
CPU03_RS14325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CPU03_RS14330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CPU03_RS14340	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CPU03_RS14350	COG2989	Protein conserved in bacteria
CPU03_RS14355	COG3108	Peptidase M15
CPU03_RS14360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPU03_RS14385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPU03_RS14395	COG1580	Controls the rotational direction of flagella during chemotaxis
CPU03_RS14410	COG1157	protein secretion by the type III secretion system
CPU03_RS14420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPU03_RS14475	COG1126	abc transporter atp-binding protein
CPU03_RS14480	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CPU03_RS14480	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CPU03_RS14485	COG0390	transport system, permease component
CPU03_RS14490	COG4619	ABC transporter
CPU03_RS14500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPU03_RS14535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPU03_RS14545	COG1530	ribonuclease E activity
CPU03_RS14560	COG1399	metal-binding, possibly nucleic acid-binding protein
CPU03_RS14580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CPU03_RS14595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPU03_RS14600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPU03_RS14605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPU03_RS14615	COG0470	DNA polymerase III
CPU03_RS14620	COG0084	hydrolase, TatD family'
CPU03_RS14625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPU03_RS14625	COG1263	PTS System
CPU03_RS14635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CPU03_RS14640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CPU03_RS14650	COG0023	Translation Initiation Factor
CPU03_RS14670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPU03_RS14700	COG1349	DNA-binding transcription factor activity
CPU03_RS14705	COG1252	NADH dehydrogenase
CPU03_RS14710	COG0697	spore germination
CPU03_RS14715	COG3134	Outer membrane lipoprotein
CPU03_RS14720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPU03_RS14725	COG4591	ABC-type transport system involved in lipoprotein release permease component
CPU03_RS14735	COG4591	ABC-type transport system involved in lipoprotein release permease component
CPU03_RS14750	COG2850	peptidyl-arginine hydroxylation
CPU03_RS14755	COG2205	protein histidine kinase activity
CPU03_RS14760	COG0745	RESPONSE REGULATOR receiver
CPU03_RS14765	COG1397	ADP-ribosylglycohydrolase
CPU03_RS14770	COG2188	Transcriptional regulator
CPU03_RS14775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPU03_RS14805	COG0538	isocitrate dehydrogenase activity
CPU03_RS14810	COG3136	membrane protein required for alginate biosynthesis
CPU03_RS14820	COG2197	response regulator
CPU03_RS14830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CPU03_RS14870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPU03_RS14870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS14870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPU03_RS14875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPU03_RS14880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPU03_RS14885	COG1882	Formate acetyltransferase
CPU03_RS14890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPU03_RS14895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPU03_RS14900	COG2207	Transcriptional regulator
CPU03_RS14910	COG0183	Belongs to the thiolase family
CPU03_RS14915	COG2031	fatty acid transporter
CPU03_RS14920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CPU03_RS14925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CPU03_RS14930	COG2204	response regulator
CPU03_RS14935	COG3852	Histidine kinase
CPU03_RS14945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CPU03_RS14950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPU03_RS14960	COG0583	DNA-binding transcription factor activity
CPU03_RS14965	COG2610	gluconate transmembrane transporter activity
CPU03_RS14990	COG1120	ATPase activity
CPU03_RS14995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPU03_RS15000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPU03_RS15090	COG1349	DNA-binding transcription factor activity
CPU03_RS15100	COG0738	Major facilitator superfamily
CPU03_RS15110	COG4772	TonB-dependent receptor
CPU03_RS15120	COG0019	diaminopimelate decarboxylase activity
CPU03_RS15130	COG2814	Major facilitator Superfamily
CPU03_RS15150	COG1120	ATPase activity
CPU03_RS15155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPU03_RS15160	COG0254	rRNA binding
CPU03_RS15165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPU03_RS15180	COG2249	NAD(P)H dehydrogenase (quinone) activity
CPU03_RS15185	COG1902	pentaerythritol trinitrate reductase activity
CPU03_RS15205	COG1486	melibiose metabolic process
CPU03_RS15215	COG0738	Major facilitator superfamily
CPU03_RS15220	COG0583	DNA-binding transcription factor activity
CPU03_RS15225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CPU03_RS15235	COG0549	Belongs to the carbamate kinase family
CPU03_RS15240	COG1304	FMN binding
CPU03_RS15245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CPU03_RS15260	COG0114	fumarate hydratase activity
CPU03_RS15270	COG0444	Belongs to the ABC transporter superfamily
CPU03_RS15275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPU03_RS15280	COG0601	transmembrane transport
CPU03_RS15285	COG0747	negative chemotaxis
CPU03_RS15315	COG2731	YhcH YjgK YiaL family protein
CPU03_RS15325	COG1231	oxidoreductase activity
CPU03_RS15335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CPU03_RS15340	COG1960	acyl-CoA dehydrogenase activity
CPU03_RS15345	COG1846	Transcriptional regulator
CPU03_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
CPU03_RS15365	COG3384	dioxygenase
CPU03_RS15375	COG2814	Major facilitator Superfamily
CPU03_RS15385	COG3971	2-oxopent-4-enoate hydratase activity
CPU03_RS15415	COG2188	Transcriptional regulator
CPU03_RS15445	COG0456	acetyltransferase
CPU03_RS15460	COG2246	polysaccharide biosynthetic process
CPU03_RS15470	COG3250	beta-galactosidase activity
CPU03_RS15475	COG0656	L-ascorbic acid biosynthetic process
CPU03_RS15510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPU03_RS15515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPU03_RS15520	COG0626	cystathionine gamma-synthase activity
CPU03_RS15550	COG4783	chaperone-mediated protein folding
CPU03_RS15555	COG2169	Transcriptional regulator
CPU03_RS15560	COG1486	melibiose metabolic process
CPU03_RS15590	COG0589	response to stress
CPU03_RS15605	COG2199	diguanylate cyclase activity
CPU03_RS15610	COG2885	chlorophyll binding
CPU03_RS15650	COG0798	PFAM Bile acid sodium symporter
CPU03_RS15665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPU03_RS15680	COG1473	amidohydrolase
CPU03_RS15680	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CPU03_RS15685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CPU03_RS15695	COG0346	lactoylglutathione lyase activity
CPU03_RS15710	COG0583	DNA-binding transcription factor activity
CPU03_RS15715	COG2828	Protein conserved in bacteria
CPU03_RS15720	COG0471	metal ion transport
CPU03_RS15725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CPU03_RS15760	COG3646	Phage regulatory protein
CPU03_RS15780	COG0582	viral genome integration into host DNA
CPU03_RS15795	COG3646	Phage regulatory protein
CPU03_RS15855	COG0464	growth
CPU03_RS15895	COG0305	Participates in initiation and elongation during chromosome replication
CPU03_RS15925	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CPU03_RS15930	COG3646	Phage regulatory protein
CPU03_RS15965	COG3561	AntA/AntB antirepressor
CPU03_RS15990	COG2026	Addiction module toxin, RelE StbE family
CPU03_RS16080	COG2200	EAL domain
CPU03_RS16100	COG1342	Belongs to the UPF0251 family
CPU03_RS16130	COG3008	intermembrane lipid transfer
CPU03_RS16135	COG2995	paraquat-inducible protein a
CPU03_RS16140	COG1956	GAF domain-containing protein
CPU03_RS16155	COG0366	Alpha amylase catalytic
CPU03_RS16160	COG0501	Belongs to the peptidase M48B family
CPU03_RS16165	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CPU03_RS16165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CPU03_RS16165	COG0506	proline dehydrogenase activity
CPU03_RS16180	COG5002	protein histidine kinase activity
CPU03_RS16185	COG0745	RESPONSE REGULATOR receiver
CPU03_RS16210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CPU03_RS16215	COG2814	Major facilitator Superfamily
CPU03_RS16220	COG0583	DNA-binding transcription factor activity
CPU03_RS16225	COG4136	ATPase activity
CPU03_RS16230	COG4135	transport system, permease component
CPU03_RS16250	COG0791	NLP P60 protein
CPU03_RS16255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CPU03_RS16260	COG2056	Na+-H+ antiporter family
CPU03_RS16265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CPU03_RS16270	COG0346	lactoylglutathione lyase activity
CPU03_RS16280	COG3133	Outer membrane lipoprotein
CPU03_RS16290	COG3895	Periplasmic Protein
CPU03_RS16310	COG0625	glutathione transferase activity
CPU03_RS16320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPU03_RS16335	COG4658	electron transport chain
CPU03_RS16360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CPU03_RS16370	COG0385	Bile acid
CPU03_RS16380	COG5339	Protein conserved in bacteria
CPU03_RS16385	COG1482	cell wall glycoprotein biosynthetic process
CPU03_RS16400	COG2814	Major facilitator Superfamily
CPU03_RS16405	COG0583	DNA-binding transcription factor activity
CPU03_RS16410	COG1940	carbohydrate kinase activity
CPU03_RS16415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CPU03_RS16420	COG1858	cytochrome C peroxidase
CPU03_RS16435	COG2814	Major facilitator Superfamily
CPU03_RS16450	COG4221	oxidoreductase activity
CPU03_RS16460	COG0589	response to stress
CPU03_RS16480	COG3065	identical protein binding
CPU03_RS16485	COG0840	transmembrane signaling receptor activity
CPU03_RS16495	COG3691	Protein conserved in bacteria
CPU03_RS16515	COG0826	peptidase U32
CPU03_RS16520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPU03_RS16530	COG0589	response to stress
CPU03_RS16535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CPU03_RS16540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CPU03_RS16550	COG0531	amino acid
CPU03_RS16560	COG1028	Short-chain dehydrogenase reductase Sdr
CPU03_RS16565	COG0745	RESPONSE REGULATOR receiver
CPU03_RS16570	COG2205	protein histidine kinase activity
CPU03_RS16595	COG3591	Belongs to the peptidase S1B family
CPU03_RS16600	COG1643	Atp-dependent helicase
CPU03_RS16605	COG3784	Protein of unknown function (DUF1318)
CPU03_RS16615	COG2911	Protein conserved in bacteria
CPU03_RS16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPU03_RS16635	COG3042	response to heat
CPU03_RS16640	COG1285	pathogenesis
CPU03_RS16650	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPU03_RS16650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPU03_RS16650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CPU03_RS16650	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPU03_RS16655	COG0493	'glutamate synthase
CPU03_RS16655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPU03_RS16675	COG2050	protein possibly involved in aromatic compounds catabolism
CPU03_RS16680	COG0247	lactate metabolic process
CPU03_RS16680	COG0277	FAD linked oxidase domain protein
CPU03_RS16685	COG0628	permease
CPU03_RS16690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPU03_RS16690	COG0574	Belongs to the PEP-utilizing enzyme family
CPU03_RS16700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CPU03_RS16725	COG4771	TonB-dependent receptor
CPU03_RS16730	COG3720	iron ion transport
CPU03_RS16735	COG4558	Periplasmic binding protein
CPU03_RS16740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPU03_RS16745	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CPU03_RS16755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPU03_RS16760	COG0791	NLP P60 protein
CPU03_RS16765	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CPU03_RS16770	COG4139	cobalamin transport
CPU03_RS16785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPU03_RS16785	COG0072	phenylalanine-tRNA ligase activity
CPU03_RS16815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPU03_RS16830	COG0783	Belongs to the Dps family
CPU03_RS16835	COG1105	Belongs to the carbohydrate kinase PfkB family
CPU03_RS16845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CPU03_RS16850	COG2267	carboxylic ester hydrolase activity
CPU03_RS16855	COG1770	oligopeptidase
CPU03_RS16895	COG1484	DNA-dependent DNA replication
CPU03_RS17060	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CPU03_RS17230	COG1475	DNA binding
CPU03_RS17295	COG1192	Involved in chromosome partitioning