locus-tag	class	description
ECAJ_RS00010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECAJ_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
ECAJ_RS00035	COG0484	heat shock protein binding
ECAJ_RS00040	COG0157	Belongs to the NadC ModD family
ECAJ_RS00045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ECAJ_RS00050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ECAJ_RS00060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ECAJ_RS00065	COG1253	flavin adenine dinucleotide binding
ECAJ_RS00075	COG4695	Portal protein
ECAJ_RS00080	COG2226	methyltransferase
ECAJ_RS00085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ECAJ_RS00090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECAJ_RS00105	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ECAJ_RS00110	COG2948	multi-organism process
ECAJ_RS00125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ECAJ_RS00135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECAJ_RS00155	COG0126	phosphoglycerate kinase activity
ECAJ_RS00175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ECAJ_RS00180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECAJ_RS00185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECAJ_RS00215	COG1230	cation diffusion facilitator family transporter
ECAJ_RS00225	COG0268	Binds directly to 16S ribosomal RNA
ECAJ_RS00250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECAJ_RS00265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECAJ_RS00270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECAJ_RS00275	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECAJ_RS00285	COG0142	geranyltranstransferase activity
ECAJ_RS00290	COG0174	glutamine synthetase
ECAJ_RS00300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ECAJ_RS00305	COG0156	8-amino-7-oxononanoate synthase activity
ECAJ_RS00310	COG0792	nuclease activity
ECAJ_RS00325	COG1830	Aldolase
ECAJ_RS00400	COG0519	Catalyzes the synthesis of GMP from XMP
ECAJ_RS00405	COG0372	Belongs to the citrate synthase family
ECAJ_RS00440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECAJ_RS00445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ECAJ_RS00450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECAJ_RS00455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ECAJ_RS00455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ECAJ_RS00460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ECAJ_RS00465	COG1138	Cytochrome C-type biogenesis protein
ECAJ_RS00470	COG0525	valine-tRNA ligase activity
ECAJ_RS00475	COG0354	folic acid binding
ECAJ_RS00480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECAJ_RS00485	COG0193	aminoacyl-tRNA hydrolase activity
ECAJ_RS00490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ECAJ_RS00500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECAJ_RS00515	COG1981	membrane
ECAJ_RS00520	COG0022	dehydrogenase e1 component
ECAJ_RS00520	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECAJ_RS00535	COG0312	modulator of DNA gyrase
ECAJ_RS00540	COG0012	GTP binding
ECAJ_RS00545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ECAJ_RS00550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ECAJ_RS00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ECAJ_RS00560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECAJ_RS00590	COG0180	Tryptophanyl-tRNA synthetase
ECAJ_RS00595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ECAJ_RS00600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECAJ_RS00600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECAJ_RS00610	COG0504	CTP synthase activity
ECAJ_RS00620	COG4974	Belongs to the 'phage' integrase family
ECAJ_RS00625	COG1136	(ABC) transporter
ECAJ_RS00630	COG0281	malic enzyme
ECAJ_RS00630	COG0280	phosphate acetyltransferase
ECAJ_RS00640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECAJ_RS00645	COG0651	ATP synthesis coupled electron transport
ECAJ_RS00665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ECAJ_RS00685	COG1840	ABC-type Fe3 transport system, periplasmic component
ECAJ_RS00690	COG0228	four-way junction DNA binding
ECAJ_RS00695	COG0477	Major facilitator Superfamily
ECAJ_RS00700	COG1028	Short-chain dehydrogenase reductase Sdr
ECAJ_RS00705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ECAJ_RS00710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ECAJ_RS00715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ECAJ_RS00725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECAJ_RS00730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECAJ_RS00755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECAJ_RS00755	COG0321	lipoyl(octanoyl) transferase activity
ECAJ_RS00760	COG0174	glutamine synthetase
ECAJ_RS00765	COG0573	inorganic phosphate transmembrane transporter activity
ECAJ_RS00770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ECAJ_RS00780	COG0045	succinate-CoA ligase (ADP-forming) activity
ECAJ_RS00785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECAJ_RS00795	COG1999	signal sequence binding
ECAJ_RS00800	COG2070	2-Nitropropane dioxygenase
ECAJ_RS00810	COG1178	ABC-type Fe3 transport system permease component
ECAJ_RS00815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECAJ_RS00835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ECAJ_RS00840	COG0049	tRNA binding
ECAJ_RS00845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECAJ_RS00850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ECAJ_RS00865	COG0250	Participates in transcription elongation, termination and antitermination
ECAJ_RS00870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ECAJ_RS00875	COG0081	regulation of translation
ECAJ_RS00880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ECAJ_RS00885	COG0222	ribosome binding
ECAJ_RS00890	COG0085	RNA polymerase activity
ECAJ_RS00895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ECAJ_RS00900	COG0156	8-amino-7-oxononanoate synthase activity
ECAJ_RS00915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ECAJ_RS00935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ECAJ_RS00940	COG0167	dihydroorotate dehydrogenase activity
ECAJ_RS00950	COG0165	Argininosuccinate lyase
ECAJ_RS00960	COG3621	Patatin-like phospholipase
ECAJ_RS00965	COG0259	pyridoxamine-phosphate oxidase activity
ECAJ_RS01005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECAJ_RS01015	COG0352	thiamine-phosphate diphosphorylase activity
ECAJ_RS01015	COG0351	phosphomethylpyrimidine kinase
ECAJ_RS01025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ECAJ_RS01035	COG0628	permease
ECAJ_RS01055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECAJ_RS01070	COG0544	peptidyl-prolyl cis-trans isomerase activity
ECAJ_RS01075	COG0740	serine-type endopeptidase activity
ECAJ_RS01080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ECAJ_RS01085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECAJ_RS01095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ECAJ_RS01100	COG1054	Belongs to the UPF0176 family
ECAJ_RS01105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ECAJ_RS01110	COG0352	thiamine-phosphate diphosphorylase activity
ECAJ_RS01115	COG4536	flavin adenine dinucleotide binding
ECAJ_RS01125	COG1674	ftsk spoiiie
ECAJ_RS01135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECAJ_RS01140	COG2202	Pas domain
ECAJ_RS01140	COG2205	protein histidine kinase activity
ECAJ_RS01145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ECAJ_RS01150	COG0758	DNA mediated transformation
ECAJ_RS01155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECAJ_RS01160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECAJ_RS01175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ECAJ_RS01185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ECAJ_RS01190	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ECAJ_RS01195	COG0482	sulfurtransferase activity
ECAJ_RS01235	COG0210	DNA helicase
ECAJ_RS01245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECAJ_RS01255	COG0326	Molecular chaperone. Has ATPase activity
ECAJ_RS01260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECAJ_RS01280	COG0625	glutathione transferase activity
ECAJ_RS01290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECAJ_RS01295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECAJ_RS01300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ECAJ_RS01310	COG1121	(ABC) transporter
ECAJ_RS01315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ECAJ_RS01325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ECAJ_RS01355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECAJ_RS01360	COG0537	adenosine 5'-monophosphoramidase activity
ECAJ_RS01370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ECAJ_RS01380	COG0113	porphobilinogen synthase activity
ECAJ_RS01390	COG0477	Major facilitator Superfamily
ECAJ_RS01395	COG0477	Major facilitator Superfamily
ECAJ_RS01400	COG0629	single-stranded DNA binding
ECAJ_RS01410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ECAJ_RS01420	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECAJ_RS01425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ECAJ_RS01435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ECAJ_RS01440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECAJ_RS01460	COG0237	dephospho-CoA kinase activity
ECAJ_RS01465	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ECAJ_RS01475	COG1758	RNA polymerase activity
ECAJ_RS01485	COG0495	leucyl-tRNA aminoacylation
ECAJ_RS01490	COG0084	hydrolase, TatD family'
ECAJ_RS01495	COG0284	orotidine-5'-phosphate decarboxylase activity
ECAJ_RS01500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ECAJ_RS01505	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ECAJ_RS01510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECAJ_RS01515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECAJ_RS01520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECAJ_RS01525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECAJ_RS01540	COG0706	membrane insertase activity
ECAJ_RS01545	COG1115	amino acid carrier protein
ECAJ_RS01550	COG1183	phosphatidylcholine synthase activity
ECAJ_RS01555	COG0688	phosphatidylethanolamine metabolic process
ECAJ_RS01560	COG0543	2 iron, 2 sulfur cluster binding
ECAJ_RS01560	COG0493	'glutamate synthase
ECAJ_RS01565	COG0688	phosphatidylethanolamine metabolic process
ECAJ_RS01570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ECAJ_RS01580	COG0564	pseudouridine synthase activity
ECAJ_RS01590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECAJ_RS01595	COG2902	Dehydrogenase
ECAJ_RS01600	COG3932	Exopolysaccharide synthesis, ExoD
ECAJ_RS01605	COG0215	cysteine-tRNA ligase activity
ECAJ_RS01620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECAJ_RS01640	COG0358	DNA primase activity
ECAJ_RS01645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECAJ_RS01650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECAJ_RS01655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ECAJ_RS01680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECAJ_RS01680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECAJ_RS01685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECAJ_RS01705	COG0736	holo-[acyl-carrier-protein] synthase activity
ECAJ_RS01710	COG0442	prolyl-tRNA aminoacylation
ECAJ_RS01725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ECAJ_RS01735	COG0492	ferredoxin-NADP+ reductase activity
ECAJ_RS01740	COG0450	alkyl hydroperoxide reductase
ECAJ_RS01745	COG0436	Aminotransferase
ECAJ_RS01755	COG1214	PFAM Peptidase M22, glycoprotease
ECAJ_RS01765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ECAJ_RS01770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ECAJ_RS01775	COG1185	polyribonucleotide nucleotidyltransferase activity
ECAJ_RS01785	COG0481	GTPase activity
ECAJ_RS01835	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECAJ_RS01840	COG0217	transcriptional regulatory protein
ECAJ_RS01845	COG0154	amidase activity
ECAJ_RS01850	COG0285	dihydrofolate synthase activity
ECAJ_RS01855	COG0181	hydroxymethylbilane synthase activity
ECAJ_RS01880	COG1217	gtp-binding protein TYPA
ECAJ_RS01890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECAJ_RS01895	COG0681	Belongs to the peptidase S26 family
ECAJ_RS01905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ECAJ_RS01925	COG0137	argininosuccinate synthase activity
ECAJ_RS01945	COG0708	Exodeoxyribonuclease III
ECAJ_RS01970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECAJ_RS02015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ECAJ_RS02020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECAJ_RS02025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECAJ_RS02035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ECAJ_RS02040	COG0302	gtp cyclohydrolase
ECAJ_RS02045	COG0312	modulator of DNA gyrase
ECAJ_RS02050	COG0492	ferredoxin-NADP+ reductase activity
ECAJ_RS02055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ECAJ_RS02065	COG0149	triose-phosphate isomerase activity
ECAJ_RS02075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ECAJ_RS02080	COG1714	RDD family
ECAJ_RS02090	COG0039	L-malate dehydrogenase activity
ECAJ_RS02105	COG0698	ribose 5-phosphate isomerase
ECAJ_RS02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECAJ_RS02115	COG3088	subunit of a heme lyase
ECAJ_RS02130	COG0443	Heat shock 70 kDa protein
ECAJ_RS02140	COG0316	Belongs to the HesB IscA family
ECAJ_RS02145	COG0822	iron-sulfur transferase activity
ECAJ_RS02150	COG1104	cysteine desulfurase activity
ECAJ_RS02155	COG1104	cysteine desulfurase activity
ECAJ_RS02160	COG2945	thiolester hydrolase activity
ECAJ_RS02165	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ECAJ_RS02185	COG0187	DNA topoisomerase II activity
ECAJ_RS02190	COG0540	Belongs to the ATCase OTCase family
ECAJ_RS02195	COG0101	tRNA pseudouridine synthase activity
ECAJ_RS02205	COG1034	ATP synthesis coupled electron transport
ECAJ_RS02210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ECAJ_RS02225	COG0649	NAD binding
ECAJ_RS02255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECAJ_RS02290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ECAJ_RS02305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ECAJ_RS02310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ECAJ_RS02315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECAJ_RS02325	COG0408	coproporphyrinogen oxidase activity
ECAJ_RS02340	COG1301	dicarboxylic acid transport
ECAJ_RS02355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ECAJ_RS02370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ECAJ_RS02385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ECAJ_RS02395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECAJ_RS02415	COG1253	flavin adenine dinucleotide binding
ECAJ_RS02425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ECAJ_RS02430	COG0195	Participates in both transcription termination and antitermination
ECAJ_RS02430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ECAJ_RS02435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECAJ_RS02440	COG0805	protein transport
ECAJ_RS02445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ECAJ_RS02455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECAJ_RS02460	COG1007	ATP synthesis coupled electron transport
ECAJ_RS02465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECAJ_RS02470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECAJ_RS02475	COG0713	ATP synthesis coupled electron transport
ECAJ_RS02520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ECAJ_RS02530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ECAJ_RS02535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ECAJ_RS02540	COG0148	phosphopyruvate hydratase activity
ECAJ_RS02545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ECAJ_RS02550	COG0275	rRNA processing
ECAJ_RS02565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECAJ_RS02570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ECAJ_RS02580	COG0018	arginyl-trna synthetase
ECAJ_RS02585	COG1381	Involved in DNA repair and RecF pathway recombination
ECAJ_RS02600	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ECAJ_RS02605	COG0606	chelatase, subunit chli
ECAJ_RS02615	COG1295	ribonuclease BN
ECAJ_RS02620	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECAJ_RS02650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ECAJ_RS02655	COG0723	plastoquinol--plastocyanin reductase activity
ECAJ_RS02665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECAJ_RS02675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ECAJ_RS02680	COG0052	Belongs to the universal ribosomal protein uS2 family
ECAJ_RS02685	COG0424	maF-like protein
ECAJ_RS02690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ECAJ_RS02700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECAJ_RS02710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ECAJ_RS02715	COG1160	GTP binding
ECAJ_RS02720	COG0505	Belongs to the CarA family
ECAJ_RS02730	COG0756	dUTP diphosphatase activity
ECAJ_RS02740	COG0419	ATPase involved in DNA repair
ECAJ_RS02740	COG3704	protein secretion by the type IV secretion system
ECAJ_RS02745	COG1340	protein secretion by the type IV secretion system
ECAJ_RS02745	COG3704	protein secretion by the type IV secretion system
ECAJ_RS02750	COG3704	protein secretion by the type IV secretion system
ECAJ_RS02755	COG3704	protein secretion by the type IV secretion system
ECAJ_RS02760	COG3451	type IV secretory pathway VirB4
ECAJ_RS02770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ECAJ_RS02775	COG0581	inorganic phosphate transmembrane transporter activity
ECAJ_RS02785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ECAJ_RS02795	COG4770	biotin carboxylase activity
ECAJ_RS02800	COG0564	pseudouridine synthase activity
ECAJ_RS02805	COG0019	diaminopimelate decarboxylase activity
ECAJ_RS02810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ECAJ_RS02840	COG3577	Aspartyl protease
ECAJ_RS02850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ECAJ_RS02855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECAJ_RS02860	COG2111	Na H antiporter
ECAJ_RS02860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECAJ_RS02865	COG2867	negative regulation of translational initiation
ECAJ_RS02870	COG0443	Heat shock 70 kDa protein
ECAJ_RS02875	COG1530	ribonuclease E activity
ECAJ_RS02880	COG1006	Multisubunit Na H antiporter MnhC subunit
ECAJ_RS02890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECAJ_RS02890	COG2111	Na H antiporter
ECAJ_RS02895	COG1320	monovalent cation:proton antiporter activity
ECAJ_RS02905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECAJ_RS02915	COG2885	chlorophyll binding
ECAJ_RS02920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ECAJ_RS02925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ECAJ_RS02930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECAJ_RS02955	COG0305	Participates in initiation and elongation during chromosome replication
ECAJ_RS02965	COG0590	tRNA wobble adenosine to inosine editing
ECAJ_RS02970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECAJ_RS02975	COG0416	fatty acid biosynthetic process
ECAJ_RS02980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ECAJ_RS02985	COG0343	queuine tRNA-ribosyltransferase activity
ECAJ_RS02995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ECAJ_RS03005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ECAJ_RS03010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ECAJ_RS03020	COG1115	amino acid carrier protein
ECAJ_RS03025	COG2333	competence protein COMEC
ECAJ_RS03025	COG0658	competence protein
ECAJ_RS03030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECAJ_RS03030	COG0072	phenylalanine-tRNA ligase activity
ECAJ_RS03035	COG0203	ribosomal protein L17
ECAJ_RS03040	COG0202	RNA polymerase activity
ECAJ_RS03045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ECAJ_RS03050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ECAJ_RS03060	COG0201	protein transport
ECAJ_RS03065	COG0200	Binds to the 23S rRNA
ECAJ_RS03070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ECAJ_RS03075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ECAJ_RS03080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ECAJ_RS03085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ECAJ_RS03090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ECAJ_RS03095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ECAJ_RS03100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ECAJ_RS03105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ECAJ_RS03110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ECAJ_RS03115	COG0255	Belongs to the universal ribosomal protein uL29 family
ECAJ_RS03120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ECAJ_RS03125	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ECAJ_RS03130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ECAJ_RS03135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ECAJ_RS03140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ECAJ_RS03150	COG0088	Forms part of the polypeptide exit tunnel
ECAJ_RS03155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ECAJ_RS03160	COG0051	transcription antitermination factor activity, RNA binding
ECAJ_RS03165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ECAJ_RS03180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECAJ_RS03185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ECAJ_RS03190	COG0539	negative regulation of cytoplasmic translation
ECAJ_RS03195	COG0616	signal peptide processing
ECAJ_RS03215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ECAJ_RS03220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECAJ_RS03245	COG1074	ATP-dependent DNA helicase activity
ECAJ_RS03250	COG0604	alcohol dehydrogenase
ECAJ_RS03250	COG3321	synthase
ECAJ_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
ECAJ_RS03270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ECAJ_RS03280	COG0114	fumarate hydratase activity
ECAJ_RS03290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ECAJ_RS03295	COG0321	lipoyl(octanoyl) transferase activity
ECAJ_RS03300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECAJ_RS03305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ECAJ_RS03315	COG0542	response to heat
ECAJ_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
ECAJ_RS03325	COG0459	protein refolding
ECAJ_RS03330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ECAJ_RS03335	COG2003	Belongs to the UPF0758 family
ECAJ_RS03340	COG0047	phosphoribosylformylglycinamidine synthase activity
ECAJ_RS03345	COG0445	tRNA wobble uridine modification
ECAJ_RS03350	COG1494	fructose-1,6-bisphosphatase
ECAJ_RS03370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECAJ_RS03375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECAJ_RS03390	COG4783	chaperone-mediated protein folding
ECAJ_RS03395	COG0799	negative regulation of ribosome biogenesis
ECAJ_RS03410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ECAJ_RS03415	COG4974	Belongs to the 'phage' integrase family
ECAJ_RS03420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ECAJ_RS03425	COG2204	response regulator
ECAJ_RS03445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ECAJ_RS03460	COG0574	Belongs to the PEP-utilizing enzyme family
ECAJ_RS03460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECAJ_RS03470	COG0651	ATP synthesis coupled electron transport
ECAJ_RS03475	COG3474	cytochrome
ECAJ_RS03490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ECAJ_RS03495	COG0194	GDP metabolic process
ECAJ_RS03500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECAJ_RS03505	COG0632	four-way junction helicase activity
ECAJ_RS03510	COG2255	four-way junction helicase activity
ECAJ_RS03515	COG2814	Major facilitator Superfamily
ECAJ_RS03540	COG1132	(ABC) transporter
ECAJ_RS03550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ECAJ_RS03555	COG0359	binds to the 23S rRNA
ECAJ_RS03560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECAJ_RS03565	COG0360	Binds together with S18 to 16S ribosomal RNA
ECAJ_RS03580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECAJ_RS03585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECAJ_RS03600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ECAJ_RS03605	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECAJ_RS03610	COG5000	phosphorelay sensor kinase activity
ECAJ_RS03625	COG0717	Belongs to the dCTP deaminase family
ECAJ_RS03630	COG4133	protoheme IX ABC transporter activity
ECAJ_RS03635	COG1612	heme a metabolic process
ECAJ_RS03640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECAJ_RS03650	COG0124	histidyl-tRNA synthetase
ECAJ_RS03655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ECAJ_RS03850	COG2094	Belongs to the DNA glycosylase MPG family
ECAJ_RS03890	COG0233	cytoplasmic translational termination
ECAJ_RS03895	COG0528	UMP kinase activity
ECAJ_RS03905	COG0328	RNA-DNA hybrid ribonuclease activity
ECAJ_RS03965	COG0307	riboflavin synthase, alpha
ECAJ_RS03975	COG0612	Peptidase, M16
ECAJ_RS03980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECAJ_RS03985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ECAJ_RS04000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECAJ_RS04005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECAJ_RS04020	COG0516	GMP reductase activity
ECAJ_RS04020	COG0517	IMP dehydrogenase activity
ECAJ_RS04035	COG2267	carboxylic ester hydrolase activity
ECAJ_RS04040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ECAJ_RS04050	COG3118	belongs to the thioredoxin family
ECAJ_RS04060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ECAJ_RS04065	COG1722	exodeoxyribonuclease VII activity
ECAJ_RS04080	COG2264	protein methyltransferase activity
ECAJ_RS04095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECAJ_RS04105	COG2022	thiamine diphosphate biosynthetic process
ECAJ_RS04120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ECAJ_RS04130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECAJ_RS04135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ECAJ_RS04140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ECAJ_RS04150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECAJ_RS04155	COG0527	aspartate kinase activity
ECAJ_RS04160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECAJ_RS04165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECAJ_RS04170	COG0109	protoheme IX farnesyltransferase activity
ECAJ_RS04175	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECAJ_RS04185	COG1862	Preprotein translocase
ECAJ_RS04200	COG0745	RESPONSE REGULATOR receiver
ECAJ_RS04210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECAJ_RS04215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECAJ_RS04225	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ECAJ_RS04240	COG0489	protein tyrosine kinase activity
ECAJ_RS04245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECAJ_RS04250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ECAJ_RS04255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECAJ_RS04265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECAJ_RS04310	COG3451	type IV secretory pathway VirB4
ECAJ_RS04335	COG0330	HflC and HflK could
ECAJ_RS04340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECAJ_RS04345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ECAJ_RS04350	COG0571	ribonuclease III activity
ECAJ_RS04360	COG0612	Peptidase, M16
ECAJ_RS04375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ECAJ_RS04380	COG0196	riboflavin kinase activity
ECAJ_RS04385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECAJ_RS04390	COG2890	protein-(glutamine-N5) methyltransferase activity
ECAJ_RS04395	COG0024	Methionine aminopeptidase
ECAJ_RS04405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECAJ_RS04410	COG1686	Belongs to the peptidase S11 family
ECAJ_RS04425	COG0750	zinc metalloprotease
ECAJ_RS04440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ECAJ_RS04445	COG0138	bifunctional purine biosynthesis protein purh
ECAJ_RS04450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECAJ_RS04455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECAJ_RS04460	COG3346	SURF1 family
ECAJ_RS04470	COG0371	Dehydrogenase
ECAJ_RS04475	COG0356	it plays a direct role in the translocation of protons across the membrane
ECAJ_RS04480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECAJ_RS04485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ECAJ_RS04500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECAJ_RS04510	COG0037	tRNA processing
ECAJ_RS04515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECAJ_RS04525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ECAJ_RS04540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECAJ_RS04545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECAJ_RS04550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ECAJ_RS04555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ECAJ_RS04560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECAJ_RS04565	COG0552	protein localization to endoplasmic reticulum
ECAJ_RS04570	COG0473	3-isopropylmalate dehydrogenase activity
ECAJ_RS04575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ECAJ_RS04575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECAJ_RS04580	COG0617	tRNA 3'-terminal CCA addition
ECAJ_RS04585	COG0105	UTP biosynthetic process
ECAJ_RS04590	COG1396	sequence-specific DNA binding
ECAJ_RS04725	COG0653	protein targeting
ECAJ_RS04755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ECAJ_RS04765	COG1475	DNA binding
ECAJ_RS04770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ECAJ_RS04775	COG0336	Belongs to the RNA methyltransferase TrmD family
ECAJ_RS04780	COG0335	large ribosomal subunit rRNA binding
ECAJ_RS04785	COG1546	Belongs to the CinA family
ECAJ_RS04785	COG1058	Belongs to the CinA family
ECAJ_RS04790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ECAJ_RS04795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ECAJ_RS04800	COG0802	atpase or kinase
ECAJ_RS04805	COG0670	Belongs to the BI1 family
ECAJ_RS04815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECAJ_RS04820	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECAJ_RS04830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECAJ_RS04840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECAJ_RS04845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme