locus-tag	class	description
FDZ61_RS00005	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FDZ61_RS00010	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FDZ61_RS00015	ENOG4105II7	pyrroline-5-carboxylate reductase
FDZ61_RS00025	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FDZ61_RS00030	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FDZ61_RS00040	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FDZ61_RS00065	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FDZ61_RS00070	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FDZ61_RS00075	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FDZ61_RS00080	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FDZ61_RS00085	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FDZ61_RS00090	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FDZ61_RS00100	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FDZ61_RS00105	ENOG4107RCQ	(CBS) domain
FDZ61_RS00120	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FDZ61_RS00125	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FDZ61_RS00130	ENOG4108Z4U	Ferredoxin
FDZ61_RS00145	ENOG4108EHY	type IV secretion system
FDZ61_RS00150	ENOG4105CMA	conjugation trbi family protein
FDZ61_RS00165	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FDZ61_RS00175	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FDZ61_RS00195	ENOG4105BZA	Phosphoglycerate kinase
FDZ61_RS00200	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FDZ61_RS00210	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FDZ61_RS00225	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FDZ61_RS00270	ENOG4105PGM	cation diffusion facilitator family transporter
FDZ61_RS00285	ENOG4105C2M	dna polymerase I
FDZ61_RS00290	ENOG4105C2M	dna polymerase I
FDZ61_RS00295	ENOG4105C2M	dna polymerase I
FDZ61_RS00305	ENOG4105DBV	ornithine carbamoyltransferase
FDZ61_RS00310	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FDZ61_RS00315	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FDZ61_RS00320	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FDZ61_RS00330	ENOG4105DJV	ribulose-phosphate 3-epimerase
FDZ61_RS00350	ENOG4105EAH	synthase
FDZ61_RS00355	ENOG4105C5F	glutamine synthetase
FDZ61_RS00365	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FDZ61_RS00370	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FDZ61_RS00380	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FDZ61_RS00390	ENOG4105EIE	fructose-bisphosphate aldolase
FDZ61_RS00435	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FDZ61_RS00465	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FDZ61_RS00480	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FDZ61_RS00485	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FDZ61_RS00490	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FDZ61_RS00530	ENOG4105DA4	cytochrome c-type biogenesis protein
FDZ61_RS00540	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FDZ61_RS00545	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FDZ61_RS00560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FDZ61_RS00575	ENOG4108YXA	Membrane
FDZ61_RS00580	ENOG4105CPP	Dehydrogenase, E1 component
FDZ61_RS00595	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FDZ61_RS00600	ENOG4105C3G	gtp-binding protein
FDZ61_RS00605	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FDZ61_RS00615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FDZ61_RS00630	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FDZ61_RS00670	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDZ61_RS00675	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FDZ61_RS00685	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FDZ61_RS00695	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FDZ61_RS00705	ENOG4105C6K	Malic enzyme
FDZ61_RS00715	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FDZ61_RS00720	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FDZ61_RS00765	ENOG4105K5M	30s ribosomal protein S16
FDZ61_RS00770	ENOG4105CSH	Transporter
FDZ61_RS00805	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FDZ61_RS00840	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FDZ61_RS00850	ENOG4105C8U	phosphate abc transporter
FDZ61_RS00855	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FDZ61_RS00860	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FDZ61_RS00865	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FDZ61_RS00875	ENOG4105CVA	phosphate
FDZ61_RS00890	ENOG4105DS1	cytochrome b561
FDZ61_RS00895	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
FDZ61_RS00925	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FDZ61_RS00955	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FDZ61_RS00965	ENOG4108VZM	50s ribosomal protein L10
FDZ61_RS00970	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FDZ61_RS00975	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FDZ61_RS00985	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FDZ61_RS01030	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FDZ61_RS01035	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FDZ61_RS01040	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FDZ61_RS01045	ENOG4105CH7	arginosuccinase
FDZ61_RS01060	ENOG4105M85	Bola protein
FDZ61_RS01075	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FDZ61_RS01085	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
FDZ61_RS01100	ENOG4105DWF	phosphomethylpyrimidine kinase
FDZ61_RS01110	ENOG4105C02	permease
FDZ61_RS01120	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FDZ61_RS01140	ENOG4108ZAI	phosphatidylglycerophosphatase a
FDZ61_RS01160	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FDZ61_RS01165	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FDZ61_RS01175	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FDZ61_RS01185	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FDZ61_RS01190	ENOG4105C72	UPF0176 protein
FDZ61_RS01195	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FDZ61_RS01200	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FDZ61_RS01205	ENOG4108JU6	CBS domain protein
FDZ61_RS01215	ENOG4105CNU	cell division protein FtsK
FDZ61_RS01225	ENOG4105C8Y	Acetylornithine aminotransferase
FDZ61_RS01230	ENOG4105BZU	Histidine kinase
FDZ61_RS01235	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FDZ61_RS01240	ENOG4105C79	DNA protecting protein DprA
FDZ61_RS01245	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FDZ61_RS01250	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FDZ61_RS01285	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FDZ61_RS01380	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FDZ61_RS01385	ENOG4105CSM	endonuclease III
FDZ61_RS01395	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FDZ61_RS01400	ENOG4105C83	adenylosuccinate lyase
FDZ61_RS01440	ENOG4108K3A	Glutathione S-transferase
FDZ61_RS01450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FDZ61_RS01455	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FDZ61_RS01460	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FDZ61_RS01475	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FDZ61_RS01485	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FDZ61_RS01515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FDZ61_RS01520	ENOG4105K59	histidine triad (HIT) protein
FDZ61_RS01530	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FDZ61_RS01540	ENOG4105C4K	Nad synthetase
FDZ61_RS01545	ENOG4105D52	delta-aminolevulinic acid dehydratase
FDZ61_RS01555	ENOG4105CSH	Transporter
FDZ61_RS01590	ENOG4105CSH	Transporter
FDZ61_RS01595	ENOG4105CSH	Transporter
FDZ61_RS01610	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FDZ61_RS01620	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FDZ61_RS01645	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FDZ61_RS01650	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FDZ61_RS01660	ENOG4107QRG	dna polymerase iii
FDZ61_RS01665	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FDZ61_RS01670	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FDZ61_RS01675	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FDZ61_RS01680	ENOG4108DG9	Smr protein MutS2
FDZ61_RS01685	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FDZ61_RS01695	ENOG4105C8T	Leucyl-tRNA synthetase
FDZ61_RS01705	ENOG4105F8V	Hydrolase, tatD family
FDZ61_RS01710	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FDZ61_RS01715	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FDZ61_RS01720	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FDZ61_RS01725	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDZ61_RS01740	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDZ61_RS01745	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FDZ61_RS01750	ENOG4107XZX	Involved in the transcription termination process (By similarity)
FDZ61_RS01760	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FDZ61_RS01765	ENOG4105BZG	amino acid carrier protein
FDZ61_RS01770	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FDZ61_RS01775	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FDZ61_RS01805	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FDZ61_RS01810	ENOG4105C7I	Dehydrogenase
FDZ61_RS01820	ENOG4105C8N	cysteinyl-tRNA synthetase
FDZ61_RS01830	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FDZ61_RS01850	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FDZ61_RS01855	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FDZ61_RS01865	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FDZ61_RS01890	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FDZ61_RS01895	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FDZ61_RS01920	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FDZ61_RS01925	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FDZ61_RS01940	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FDZ61_RS01945	ENOG4105C3M	thioredoxin reductase
FDZ61_RS01950	ENOG4105D3R	alkyl hydroperoxide reductase
FDZ61_RS01965	ENOG41072GX	Peptidase M22 Glycoprotease
FDZ61_RS01985	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FDZ61_RS01995	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FDZ61_RS02060	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FDZ61_RS02065	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FDZ61_RS02070	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FDZ61_RS02075	ENOG4105CI3	gtp-binding protein typa
FDZ61_RS02085	ENOG4105C3F	Signal peptidase i
FDZ61_RS02095	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FDZ61_RS02115	ENOG4105CDH	Citrulline--aspartate ligase
FDZ61_RS02135	ENOG4105CGK	Exodeoxyribonuclease III
FDZ61_RS02160	ENOG4105C26	Dehydrogenase
FDZ61_RS02170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FDZ61_RS02220	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FDZ61_RS02235	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FDZ61_RS02240	ENOG4105EUJ	GTP cyclohydrolase i
FDZ61_RS02245	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FDZ61_RS02250	ENOG4105CAY	ferredoxin--nadp reductase
FDZ61_RS02255	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FDZ61_RS02265	ENOG4105CP7	Triose-phosphate isomerase
FDZ61_RS02275	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FDZ61_RS02285	ENOG41085PJ	rdd domain containing protein
FDZ61_RS02305	ENOG4108YZG	isomerase
FDZ61_RS02310	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FDZ61_RS02325	ENOG4105DHZ	alpha beta
FDZ61_RS02330	ENOG4107QI6	Cysteine desulfurase
FDZ61_RS02335	ENOG4105C3J	Cysteine desulfurase
FDZ61_RS02340	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FDZ61_RS02345	ENOG4108Z4V	iron-sulfur cluster assembly
FDZ61_RS02350	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
FDZ61_RS02355	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
FDZ61_RS02370	ENOG4105KWW	Biogenesis protein
FDZ61_RS02375	ENOG4105DK7	lysyl-tRNA synthetase
FDZ61_RS02395	ENOG4105CXT	aspartate transcarbamylase
FDZ61_RS02410	ENOG4108IEH	NADH dehydrogenase subunit g
FDZ61_RS02430	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FDZ61_RS02445	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FDZ61_RS02465	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FDZ61_RS02490	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FDZ61_RS02495	ENOG4105GKE	subunit e
FDZ61_RS02500	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FDZ61_RS02530	ENOG4108EXS	Amino acid kinase family
FDZ61_RS02535	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FDZ61_RS02545	ENOG4107QJT	sodium dicarboxylate symporter
FDZ61_RS02560	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FDZ61_RS02565	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FDZ61_RS02570	ENOG4105Y2X	UPF0335 protein
FDZ61_RS02575	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FDZ61_RS02585	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FDZ61_RS02630	ENOG4105EE5	Membrane protein terC
FDZ61_RS02635	ENOG4108AGE	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FDZ61_RS02640	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FDZ61_RS02650	ENOG4105BZS	acriflavin resistance protein
FDZ61_RS02655	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FDZ61_RS02660	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FDZ61_RS02670	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FDZ61_RS02675	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FDZ61_RS02680	ENOG4105C8S	subunit m
FDZ61_RS02690	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FDZ61_RS02695	ENOG4105DF2	NADH dehydrogenase subunit j
FDZ61_RS02700	ENOG4107QIZ	NADH dehydrogenase
FDZ61_RS02715	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FDZ61_RS02720	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FDZ61_RS02725	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDZ61_RS02730	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FDZ61_RS02735	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FDZ61_RS02740	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDZ61_RS02750	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FDZ61_RS02755	ENOG4105C75	arginyL-tRNA synthetase
FDZ61_RS02760	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
FDZ61_RS02775	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FDZ61_RS02785	ENOG4105C0P	Mg chelatase subunit ChlI
FDZ61_RS02800	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FDZ61_RS02820	ENOG4105EIX	cytochrome c1
FDZ61_RS02825	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FDZ61_RS02840	ENOG4105CC5	ABC transporter
FDZ61_RS02850	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FDZ61_RS02860	ENOG4108Z03	MAF-like protein
FDZ61_RS02865	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FDZ61_RS02870	ENOG4105Y49	secretion protein, HlyD family
FDZ61_RS02875	ENOG4107QN2	dihydrolipoyl dehydrogenase
FDZ61_RS02885	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FDZ61_RS02890	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FDZ61_RS02895	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FDZ61_RS02900	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FDZ61_RS02905	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FDZ61_RS02920	ENOG4108QTG	type IV secretion system protein
FDZ61_RS02925	ENOG4106Q4M	protein secretion by the type IV secretion system
FDZ61_RS02945	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FDZ61_RS02950	ENOG4105E2Z	phosphate ABC transporter (Permease
FDZ61_RS02990	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FDZ61_RS02995	ENOG4105KDC	50s ribosomal protein l28
FDZ61_RS03015	ENOG4105DC7	peptidase M24
FDZ61_RS03020	ENOG4108WIW	Aspartyl protease
FDZ61_RS03030	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FDZ61_RS03035	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDZ61_RS03060	ENOG4108Z1B	Cyclase dehydrase
FDZ61_RS03070	ENOG4105CFG	Acts as a chaperone (By similarity)
FDZ61_RS03075	ENOG4105C03	ribonuclease
FDZ61_RS03090	ENOG4105C8S	subunit m
FDZ61_RS03130	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FDZ61_RS03135	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FDZ61_RS03140	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FDZ61_RS03145	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FDZ61_RS03170	ENOG4108Z6B	deaminase
FDZ61_RS03175	ENOG4108Z6B	deaminase
FDZ61_RS03190	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FDZ61_RS03205	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FDZ61_RS03225	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FDZ61_RS03235	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FDZ61_RS03240	ENOG4105BZG	amino acid carrier protein
FDZ61_RS03245	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FDZ61_RS03250	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FDZ61_RS03260	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FDZ61_RS03285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FDZ61_RS03300	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FDZ61_RS03315	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDZ61_RS03345	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FDZ61_RS03355	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FDZ61_RS03370	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FDZ61_RS03375	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FDZ61_RS03380	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FDZ61_RS03400	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FDZ61_RS03410	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FDZ61_RS03415	ENOG4105D07	Signal peptide peptidase, SppA
FDZ61_RS03420	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FDZ61_RS03440	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FDZ61_RS03475	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FDZ61_RS03480	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FDZ61_RS03485	ENOG4108JJ6	Type I secretion system ATPase
FDZ61_RS03490	ENOG4105EEI	dihydropteroate synthase
FDZ61_RS03495	ENOG4105EEI	dihydropteroate synthase
FDZ61_RS03505	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FDZ61_RS03525	ENOG4105CD3	dihydroorotase
FDZ61_RS03535	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FDZ61_RS03540	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FDZ61_RS03550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FDZ61_RS03555	ENOG4105EMU	Dehydrogenase
FDZ61_RS03560	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FDZ61_RS03565	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FDZ61_RS03570	ENOG4105W5Q	DNA repair protein (RadC
FDZ61_RS03575	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
FDZ61_RS03580	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FDZ61_RS03585	ENOG4105CBT	Fructose-1,6-bisphosphatase
FDZ61_RS03605	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FDZ61_RS03615	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FDZ61_RS03620	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDZ61_RS03630	ENOG4105ERG	peptidase m48, ste24p
FDZ61_RS03650	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FDZ61_RS03655	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FDZ61_RS03660	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FDZ61_RS03670	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FDZ61_RS03680	ENOG4105D7Z	glutathione synthase
FDZ61_RS03685	ENOG41082WC	Transport-associated protein
FDZ61_RS03690	ENOG4105C9M	aspartyl-trna synthetase
FDZ61_RS03710	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FDZ61_RS03715	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FDZ61_RS03725	ENOG4105G9V	cytochrome C
FDZ61_RS03735	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FDZ61_RS03745	ENOG41060IM	Heme exporter protein
FDZ61_RS03750	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FDZ61_RS03765	ENOG4105C2C	drug resistance transporter, Bcr CflA
FDZ61_RS03775	ENOG4105E33	succinate dehydrogenase
FDZ61_RS03785	ENOG4105BZ1	(ABC) transporter
FDZ61_RS03815	ENOG4105E96	Colicin v production protein
FDZ61_RS03830	ENOG4107QX9	Thiol disulfide interChange protein
FDZ61_RS03840	ENOG4105M2J	Glutaredoxin
FDZ61_RS03845	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FDZ61_RS03850	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FDZ61_RS03870	ENOG4105DHP	deoxycytidine triphosphate deaminase
FDZ61_RS03875	ENOG4107QPR	SAICAR synthetase
FDZ61_RS03880	ENOG4105CUT	histidyl-tRNA synthetase
FDZ61_RS03900	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FDZ61_RS03905	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FDZ61_RS03970	ENOG4108VX5	3-methyladenine DNA glycosylase
FDZ61_RS04010	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FDZ61_RS04040	ENOG4108JA2	transcriptioN-repair coupling factor
FDZ61_RS04100	ENOG4108R6K	riboflavin synthase, subunit alpha
FDZ61_RS04110	ENOG4105C1V	Peptidase, M16
FDZ61_RS04115	ENOG4108R9S	DSBA oxidoreductase
FDZ61_RS04120	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FDZ61_RS04140	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FDZ61_RS04150	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FDZ61_RS04155	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FDZ61_RS04175	ENOG4107R0V	Pyruvate dehydrogenase
FDZ61_RS04185	ENOG4105K63	Thioredoxin
FDZ61_RS04190	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FDZ61_RS04215	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FDZ61_RS04235	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FDZ61_RS04245	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FDZ61_RS04260	ENOG41083MR	nifu domain-containing protein
FDZ61_RS04270	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FDZ61_RS04275	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FDZ61_RS04280	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FDZ61_RS04295	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FDZ61_RS04300	ENOG4105CFH	Aspartokinase
FDZ61_RS04310	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FDZ61_RS04315	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FDZ61_RS04320	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDZ61_RS04330	ENOG4105VIE	preprotein translocase, subunit YajC
FDZ61_RS04345	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FDZ61_RS04350	ENOG4108UJD	30S ribosomal protein S9
FDZ61_RS04360	ENOG4105F0N	pyrophosphate phospho-hydrolase
FDZ61_RS04370	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
FDZ61_RS04385	ENOG4105D1F	ATP-binding protein
FDZ61_RS04390	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FDZ61_RS04395	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FDZ61_RS04400	ENOG4108I0Z	Aconitate hydratase
FDZ61_RS04410	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FDZ61_RS04455	ENOG4107RIZ	hflk protein
FDZ61_RS04460	ENOG4105EPW	hflc protein
FDZ61_RS04465	ENOG4105C0H	protease
FDZ61_RS04475	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FDZ61_RS04480	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
FDZ61_RS04500	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FDZ61_RS04505	ENOG4105DTN	riboflavin biosynthesis protein ribF
FDZ61_RS04510	ENOG4105VW4	glutaredoxin 3
FDZ61_RS04515	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FDZ61_RS04520	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FDZ61_RS04540	ENOG4105C7S	Dehydrogenase
FDZ61_RS04555	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FDZ61_RS04565	ENOG4105DZP	Membrane-associated zinc metalloprotease
FDZ61_RS04570	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDZ61_RS04580	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FDZ61_RS04585	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FDZ61_RS04590	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FDZ61_RS04595	ENOG4108KAG	Cytochrome C oxidase, subunit I
FDZ61_RS04600	ENOG4108R6F	Surfeit locus 1 family protein
FDZ61_RS04615	ENOG4108MDK	Dehydrogenase
FDZ61_RS04625	ENOG41085Y2	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FDZ61_RS04630	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FDZ61_RS04640	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FDZ61_RS04645	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FDZ61_RS04655	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FDZ61_RS04660	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FDZ61_RS04665	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FDZ61_RS04685	ENOG4105D06	uba thif-type nad fad binding protein
FDZ61_RS04690	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FDZ61_RS04700	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FDZ61_RS04720	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FDZ61_RS04725	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FDZ61_RS04730	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FDZ61_RS04735	ENOG4108WRK	Transcriptional regulator
FDZ61_RS04740	ENOG4106WCW	Major outer membrane protein
FDZ61_RS04770	ENOG4106WCW	Major outer membrane protein
FDZ61_RS04775	ENOG4106WCW	Major outer membrane protein
FDZ61_RS04810	ENOG4106WCW	Major outer membrane protein
FDZ61_RS04815	ENOG4106WCW	Major outer membrane protein
FDZ61_RS04850	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FDZ61_RS04870	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FDZ61_RS04875	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FDZ61_RS04880	ENOG4105CEV	competence damage-inducible protein
FDZ61_RS04885	ENOG4105C22	threonyL-tRNA synthetase
FDZ61_RS04895	ENOG4108E87	P-loop hydrolase UPF0079
FDZ61_RS04900	ENOG4105HFZ	Membrane