locus-tag	class	description
EZJ17_RS00040	COG0786	glutamate:sodium symporter activity
EZJ17_RS00070	COG0433	COG0433 Predicted ATPase
EZJ17_RS00100	COG0742	ribosomal rna small subunit methyltransferase
EZJ17_RS00105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EZJ17_RS00190	COG0424	maF-like protein
EZJ17_RS00200	COG2226	methyltransferase
EZJ17_RS00210	COG4783	chaperone-mediated protein folding
EZJ17_RS00225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EZJ17_RS00230	COG2884	Cell division ATP-binding protein ftsE
EZJ17_RS00255	COG1673	EVE domain
EZJ17_RS00275	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EZJ17_RS00300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EZJ17_RS00305	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EZJ17_RS00310	COG0729	surface antigen
EZJ17_RS00315	COG2911	Protein conserved in bacteria
EZJ17_RS00345	COG0307	riboflavin synthase, alpha
EZJ17_RS00375	COG0582	viral genome integration into host DNA
EZJ17_RS00425	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EZJ17_RS00500	COG0833	amino acid
EZJ17_RS00630	COG0200	Binds to the 23S rRNA
EZJ17_RS00635	COG0201	protein transport
EZJ17_RS00645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EZJ17_RS00680	COG0859	PFAM glycosyl transferase family 9
EZJ17_RS00685	COG0415	Belongs to the DNA photolyase family
EZJ17_RS00735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EZJ17_RS00745	COG0515	serine threonine protein kinase
EZJ17_RS00750	COG3264	Mechanosensitive ion channel
EZJ17_RS00750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EZJ17_RS00755	COG0494	nUDIX hydrolase
EZJ17_RS00815	COG1960	acyl-CoA dehydrogenase activity
EZJ17_RS00830	COG1346	cytolysis
EZJ17_RS00835	COG1380	Effector of murein hydrolase LrgA
EZJ17_RS00845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EZJ17_RS00855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EZJ17_RS00900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EZJ17_RS00905	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EZJ17_RS00965	COG0196	riboflavin kinase activity
EZJ17_RS00985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EZJ17_RS00990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EZJ17_RS01030	COG2056	Na+-H+ antiporter family
EZJ17_RS01035	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EZJ17_RS01045	COG1902	pentaerythritol trinitrate reductase activity
EZJ17_RS01050	COG1125	glycine betaine transport
EZJ17_RS01050	COG0517	IMP dehydrogenase activity
EZJ17_RS01065	COG1174	glycine betaine transport
EZJ17_RS01090	COG0730	response to heat
EZJ17_RS01115	COG5301	cellulose 1,4-beta-cellobiosidase activity
EZJ17_RS01350	COG2369	cell adhesion
EZJ17_RS01360	COG5005	Phage virion morphogenesis
EZJ17_RS01370	COG0523	cobalamin synthesis protein
EZJ17_RS01380	COG4221	oxidoreductase activity
EZJ17_RS01415	COG2217	Heavy metal translocating P-type atpase
EZJ17_RS01420	COG2608	mercury ion transmembrane transporter activity
EZJ17_RS01425	COG0789	Transcriptional regulator
EZJ17_RS01440	COG0842	Transport permease protein
EZJ17_RS01445	COG0842	Transport permease protein
EZJ17_RS01445	COG1129	ABC transporter
EZJ17_RS01450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EZJ17_RS01470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EZJ17_RS01515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EZJ17_RS01595	COG0084	hydrolase, TatD family'
EZJ17_RS01610	COG0586	Pfam SNARE associated Golgi protein
EZJ17_RS01615	COG0488	(ABC) transporter
EZJ17_RS01630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EZJ17_RS01645	COG0167	dihydroorotate dehydrogenase activity
EZJ17_RS01695	COG0513	Belongs to the DEAD box helicase family
EZJ17_RS01700	COG1187	pseudouridine synthase activity
EZJ17_RS01730	COG0708	Exodeoxyribonuclease III
EZJ17_RS01750	COG0285	dihydrofolate synthase activity
EZJ17_RS01765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EZJ17_RS01775	COG1562	ergosterol biosynthetic process
EZJ17_RS01790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EZJ17_RS01800	COG1464	Belongs to the NlpA lipoprotein family
EZJ17_RS01810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EZJ17_RS01820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EZJ17_RS01835	COG1561	YicC-like family, N-terminal region
EZJ17_RS01855	COG2962	Rard protein
EZJ17_RS01905	COG1530	ribonuclease E activity
EZJ17_RS01910	COG0564	pseudouridine synthase activity
EZJ17_RS01925	COG0546	phosphoglycolate phosphatase activity
EZJ17_RS01935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EZJ17_RS01945	COG1121	(ABC) transporter
EZJ17_RS01965	COG0803	Belongs to the bacterial solute-binding protein 9 family
EZJ17_RS01985	COG1757	Na H antiporter
EZJ17_RS02005	COG0733	neurotransmitter:sodium symporter activity
EZJ17_RS02015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EZJ17_RS02030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EZJ17_RS02060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EZJ17_RS02095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EZJ17_RS02135	COG0582	viral genome integration into host DNA
EZJ17_RS02145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EZJ17_RS02170	COG1399	metal-binding, possibly nucleic acid-binding protein
EZJ17_RS02185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EZJ17_RS02200	COG0765	amino acid transport
EZJ17_RS02215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EZJ17_RS02245	COG2453	phosphatase
EZJ17_RS02245	COG0671	phosphoesterase, PA-phosphatase related
EZJ17_RS02255	COG2267	carboxylic ester hydrolase activity
EZJ17_RS02270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EZJ17_RS02280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EZJ17_RS02285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EZJ17_RS02295	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EZJ17_RS02300	COG1393	Belongs to the ArsC family
EZJ17_RS02345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EZJ17_RS02350	COG0501	Belongs to the peptidase M48B family
EZJ17_RS02360	COG1619	proteins homologs of microcin C7 resistance protein MccF
EZJ17_RS02370	COG4475	Protein of unknown function (DUF436)
EZJ17_RS02380	COG1505	serine-type exopeptidase activity
EZJ17_RS02385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EZJ17_RS02390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EZJ17_RS02475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EZJ17_RS02480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EZJ17_RS02485	COG0778	Nitroreductase
EZJ17_RS02490	COG3681	Belongs to the UPF0597 family
EZJ17_RS02495	COG0814	amino acid
EZJ17_RS02500	COG2964	Protein conserved in bacteria
EZJ17_RS02575	COG0859	PFAM glycosyl transferase family 9
EZJ17_RS02605	COG0583	DNA-binding transcription factor activity
EZJ17_RS02680	COG2264	protein methyltransferase activity
EZJ17_RS02700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EZJ17_RS02705	COG0281	malic enzyme
EZJ17_RS02705	COG0280	phosphate acetyltransferase
EZJ17_RS02725	COG0277	FAD linked oxidase domain protein
EZJ17_RS02735	COG1126	abc transporter atp-binding protein
EZJ17_RS02755	COG0436	Aminotransferase
EZJ17_RS02785	COG1448	Aminotransferase
EZJ17_RS02790	COG1073	alpha beta
EZJ17_RS02830	COG2824	Alkylphosphonate utilization operon protein PhnA
EZJ17_RS02870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EZJ17_RS02890	COG0557	exoribonuclease II activity
EZJ17_RS02925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EZJ17_RS02985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EZJ17_RS03005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EZJ17_RS03015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EZJ17_RS03035	COG1027	Aspartate ammonia-lyase
EZJ17_RS03065	COG1881	PFAM PEBP family protein
EZJ17_RS03070	COG2233	PERMEase
EZJ17_RS03090	COG2239	Acts as a magnesium transporter
EZJ17_RS03125	COG2252	PERMEase
EZJ17_RS03170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EZJ17_RS03175	COG1047	Peptidyl-prolyl cis-trans
EZJ17_RS03185	COG2226	methyltransferase
EZJ17_RS03200	COG2378	regulation of single-species biofilm formation
EZJ17_RS03230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EZJ17_RS03240	COG1560	Kdo2-lipid A biosynthetic process
EZJ17_RS03280	COG0308	aminopeptidase N
EZJ17_RS03290	COG2959	enzyme of heme biosynthesis
EZJ17_RS03315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EZJ17_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
EZJ17_RS03335	COG0714	Associated with various cellular activities
EZJ17_RS03355	COG0195	Participates in both transcription termination and antitermination
EZJ17_RS03380	COG1752	Esterase of the alpha-beta hydrolase superfamily
EZJ17_RS03440	COG0783	Belongs to the Dps family
EZJ17_RS03485	COG1882	Formate acetyltransferase
EZJ17_RS03490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EZJ17_RS03525	COG0633	Ferredoxin
EZJ17_RS03530	COG3015	lipoprotein NlpE involved in copper resistance
EZJ17_RS03585	COG0733	neurotransmitter:sodium symporter activity
EZJ17_RS03605	COG0038	chloride channel
EZJ17_RS03615	COG1297	OPT oligopeptide transporter protein
EZJ17_RS03635	COG3392	D12 class N6 adenine-specific DNA methyltransferase
EZJ17_RS03745	COG4397	Mu-like prophage major head subunit gpT
EZJ17_RS03765	COG4383	Mu-like prophage protein gp29
EZJ17_RS03835	COG0776	regulation of translation
EZJ17_RS03860	COG4396	Host-nuclease inhibitor protein Gam
EZJ17_RS03905	COG3423	Transcriptional regulator
EZJ17_RS03910	COG2932	Transcriptional regulator
EZJ17_RS03925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EZJ17_RS03955	COG0248	Ppx GppA phosphatase
EZJ17_RS03965	COG2962	Rard protein
EZJ17_RS03980	COG2814	Major facilitator Superfamily
EZJ17_RS03990	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EZJ17_RS03995	COG0351	phosphomethylpyrimidine kinase
EZJ17_RS04010	COG2321	neutral zinc metallopeptidase
EZJ17_RS04020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EZJ17_RS04050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EZJ17_RS04110	COG0741	lytic transglycosylase activity
EZJ17_RS04150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EZJ17_RS04155	COG3738	Protein conserved in bacteria
EZJ17_RS04160	COG1187	pseudouridine synthase activity
EZJ17_RS04170	COG1275	C4-dicarboxylate transporter malic acid transport protein
EZJ17_RS04210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EZJ17_RS04220	COG0488	(ABC) transporter
EZJ17_RS04240	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EZJ17_RS04275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EZJ17_RS04280	COG1686	Belongs to the peptidase S11 family
EZJ17_RS04290	COG1199	ATP-dependent helicase activity
EZJ17_RS04315	COG1530	ribonuclease E activity
EZJ17_RS04320	COG1970	mechanosensitive ion channel activity
EZJ17_RS04340	COG0012	GTP binding
EZJ17_RS04345	COG0142	geranyltranstransferase activity
EZJ17_RS04395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EZJ17_RS04440	COG2304	oxidoreductase activity
EZJ17_RS04535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EZJ17_RS04545	COG1660	Displays ATPase and GTPase activities
EZJ17_RS04550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EZJ17_RS04555	COG2969	positive regulation of protein catabolic process
EZJ17_RS04560	COG0625	glutathione transferase activity
EZJ17_RS04565	COG0187	DNA topoisomerase II activity
EZJ17_RS04570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EZJ17_RS04575	COG1794	racemase activity, acting on amino acids and derivatives
EZJ17_RS04590	COG0488	(ABC) transporter
EZJ17_RS04595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EZJ17_RS04600	COG1278	Cold shock
EZJ17_RS04610	COG0542	response to heat
EZJ17_RS04615	COG1714	RDD family
EZJ17_RS04635	COG0714	Associated with various cellular activities
EZJ17_RS04650	COG1496	oxidoreductase activity
EZJ17_RS04655	COG2866	Carboxypeptidase
EZJ17_RS04670	COG1132	(ABC) transporter
EZJ17_RS04690	COG4178	(ABC) transporter
EZJ17_RS04705	COG1704	LemA family
EZJ17_RS04765	COG0613	PHP domain protein
EZJ17_RS04805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EZJ17_RS04840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EZJ17_RS04855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EZJ17_RS04860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EZJ17_RS04865	COG1121	(ABC) transporter
EZJ17_RS04875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EZJ17_RS04890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EZJ17_RS04925	COG2837	iron assimilation
EZJ17_RS04930	COG1114	Component of the transport system for branched-chain amino acids
EZJ17_RS04935	COG1696	Membrane protein involved in D-alanine export
EZJ17_RS04970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EZJ17_RS04970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EZJ17_RS04990	COG1546	Belongs to the CinA family
EZJ17_RS04990	COG1058	Belongs to the CinA family
EZJ17_RS04995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EZJ17_RS04995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EZJ17_RS05020	COG0312	modulator of DNA gyrase
EZJ17_RS05075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EZJ17_RS05085	COG0626	cystathionine gamma-synthase activity
EZJ17_RS05095	COG2226	methyltransferase
EZJ17_RS05100	COG0741	lytic transglycosylase activity
EZJ17_RS05100	COG1388	LysM domain
EZJ17_RS05105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EZJ17_RS05110	COG2990	Protein conserved in bacteria
EZJ17_RS05130	COG1063	alcohol dehydrogenase
EZJ17_RS05155	COG1686	Belongs to the peptidase S11 family
EZJ17_RS05165	COG1040	competence protein
EZJ17_RS05170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EZJ17_RS05205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EZJ17_RS05215	COG0084	hydrolase, TatD family'
EZJ17_RS05225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EZJ17_RS05235	COG2878	Part of a membrane complex involved in electron transport
EZJ17_RS05265	COG0567	Dehydrogenase, E1 component
EZJ17_RS05270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EZJ17_RS05300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EZJ17_RS05320	COG0697	spore germination
EZJ17_RS05325	COG1629	transport
EZJ17_RS05365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EZJ17_RS05375	COG0705	Rhomboid family
EZJ17_RS05380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EZJ17_RS05395	COG0024	Methionine aminopeptidase
EZJ17_RS05410	COG2999	glutathione oxidoreductase activity
EZJ17_RS05415	COG2733	membrane
EZJ17_RS05425	COG0778	Nitroreductase
EZJ17_RS05450	COG1575	Belongs to the MenA family. Type 1 subfamily
EZJ17_RS05470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EZJ17_RS05475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EZJ17_RS05495	COG4783	chaperone-mediated protein folding
EZJ17_RS05505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EZJ17_RS05550	COG1074	ATP-dependent DNA helicase activity
EZJ17_RS05560	COG0826	peptidase U32
EZJ17_RS05565	COG2814	Major facilitator Superfamily
EZJ17_RS05610	COG0514	ATP-dependent DNA helicase (RecQ)
EZJ17_RS05630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EZJ17_RS05640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EZJ17_RS05655	COG2902	Dehydrogenase
EZJ17_RS05665	COG0456	acetyltransferase
EZJ17_RS05695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EZJ17_RS05755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EZJ17_RS05760	COG0617	tRNA 3'-terminal CCA addition
EZJ17_RS05820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EZJ17_RS05830	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EZJ17_RS05865	COG0708	Exodeoxyribonuclease III
EZJ17_RS05870	COG2975	iron-sulfur cluster assembly
EZJ17_RS05875	COG0633	Ferredoxin
EZJ17_RS05880	COG2951	lytic endotransglycosylase activity
EZJ17_RS05890	COG0802	atpase or kinase
EZJ17_RS05905	COG3111	PFAM Bacterial OB fold (BOF) protein
EZJ17_RS05925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EZJ17_RS05930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EZJ17_RS05945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EZJ17_RS05970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EZJ17_RS06005	COG0814	amino acid
EZJ17_RS06035	COG0791	NLP P60 protein
EZJ17_RS06075	COG2839	Protein conserved in bacteria
EZJ17_RS06090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EZJ17_RS06105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EZJ17_RS06120	COG0793	Belongs to the peptidase S41A family
EZJ17_RS06125	COG1012	belongs to the aldehyde dehydrogenase family
EZJ17_RS06135	COG0268	Binds directly to 16S ribosomal RNA
EZJ17_RS06140	COG0628	permease
EZJ17_RS06160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EZJ17_RS06190	COG2995	paraquat-inducible protein a
EZJ17_RS06195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EZJ17_RS06195	COG3008	intermembrane lipid transfer
EZJ17_RS06230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EZJ17_RS06260	COG1610	YqeY-like protein
EZJ17_RS06275	COG5005	Phage virion morphogenesis
EZJ17_RS06280	COG2369	cell adhesion
EZJ17_RS06310	COG0668	transmembrane transport
EZJ17_RS06320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EZJ17_RS06380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EZJ17_RS06385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EZJ17_RS06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
EZJ17_RS06400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EZJ17_RS06430	COG0582	viral genome integration into host DNA
EZJ17_RS06655	COG4589	Belongs to the CDS family
EZJ17_RS06690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EZJ17_RS06705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EZJ17_RS06710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EZJ17_RS06725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EZJ17_RS06735	COG0513	Belongs to the DEAD box helicase family
EZJ17_RS06740	COG0305	Participates in initiation and elongation during chromosome replication
EZJ17_RS06790	COG0492	ferredoxin-NADP+ reductase activity
EZJ17_RS06795	COG1555	photosystem II stabilization
EZJ17_RS06830	COG2095	MarC family integral membrane protein
EZJ17_RS06840	COG0772	Belongs to the SEDS family
EZJ17_RS06845	COG0768	penicillin binding
EZJ17_RS06855	COG1792	Involved in formation and maintenance of cell shape
EZJ17_RS06860	COG1077	Cell shape determining protein MreB Mrl
EZJ17_RS06885	COG0210	DNA helicase
EZJ17_RS06930	COG2823	Periplasmic or secreted lipoprotein
EZJ17_RS06990	COG1562	ergosterol biosynthetic process
EZJ17_RS07045	COG0318	PFAM AMP-dependent synthetase and ligase
EZJ17_RS07080	COG0739	heme binding
EZJ17_RS07090	COG1652	LysM domain
EZJ17_RS07115	COG5000	phosphorelay sensor kinase activity
EZJ17_RS07120	COG2204	response regulator
EZJ17_RS07150	COG2966	Psort location CytoplasmicMembrane, score
EZJ17_RS07155	COG3610	response to peptide
EZJ17_RS07195	COG0501	Belongs to the peptidase M48B family
EZJ17_RS07200	COG0659	secondary active sulfate transmembrane transporter activity
EZJ17_RS07235	COG0402	S-adenosylhomocysteine deaminase activity
EZJ17_RS07255	COG0586	Pfam SNARE associated Golgi protein
EZJ17_RS07290	COG2350	Protein conserved in bacteria
EZJ17_RS07310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EZJ17_RS07385	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EZJ17_RS07480	COG0191	fructose-bisphosphate aldolase activity
EZJ17_RS07490	COG2814	Major facilitator Superfamily
EZJ17_RS07625	COG1335	isochorismatase
EZJ17_RS07645	COG0822	iron-sulfur transferase activity
EZJ17_RS07650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EZJ17_RS07675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EZJ17_RS07720	COG1131	(ABC) transporter
EZJ17_RS07735	COG0497	DNA recombination
EZJ17_RS07785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EZJ17_RS07805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EZJ17_RS07810	COG1216	Glycosyl transferase, family 2
EZJ17_RS07825	COG2244	polysaccharide biosynthetic process
EZJ17_RS07830	COG2089	acid synthase
EZJ17_RS07840	COG1083	cytidylyl-transferase
EZJ17_RS07860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EZJ17_RS07870	COG1086	Polysaccharide biosynthesis protein
EZJ17_RS07895	COG0582	viral genome integration into host DNA
EZJ17_RS07910	COG1595	DNA-templated transcription, initiation
EZJ17_RS07915	COG0537	adenosine 5'-monophosphoramidase activity
EZJ17_RS07965	COG1127	ABC transporter
EZJ17_RS07970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EZJ17_RS07975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EZJ17_RS08000	COG0824	Thioesterase
EZJ17_RS08035	COG0471	metal ion transport
EZJ17_RS08040	COG0142	geranyltranstransferase activity
EZJ17_RS08055	COG2832	Protein of unknown function (DUF454)
EZJ17_RS08060	COG1702	phosphate starvation-inducible protein PhoH
EZJ17_RS08095	COG0009	L-threonylcarbamoyladenylate synthase
EZJ17_RS08105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EZJ17_RS08120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EZJ17_RS08130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EZJ17_RS08140	COG2885	chlorophyll binding
EZJ17_RS08145	COG3842	ATPase activity
EZJ17_RS08150	COG1176	ABC-type spermidine putrescine transport system, permease component I
EZJ17_RS08155	COG1177	transmembrane transport
EZJ17_RS08240	COG1760	l-serine dehydratase
EZJ17_RS08245	COG0814	amino acid
EZJ17_RS08310	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EZJ17_RS08315	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EZJ17_RS08335	COG1064	alcohol dehydrogenase
EZJ17_RS08345	COG0312	modulator of DNA gyrase
EZJ17_RS08350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EZJ17_RS08355	COG0833	amino acid
EZJ17_RS08410	COG0356	it plays a direct role in the translocation of protons across the membrane
EZJ17_RS08425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EZJ17_RS08430	COG0483	inositol monophosphate 1-phosphatase activity
EZJ17_RS08495	COG0739	heme binding
EZJ17_RS08545	COG0531	amino acid
EZJ17_RS08550	COG1982	Orn Lys Arg decarboxylase major
EZJ17_RS08565	COG3104	oligopeptide transport
EZJ17_RS08570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EZJ17_RS08605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EZJ17_RS08620	COG2223	nitrite transmembrane transporter activity
EZJ17_RS08655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EZJ17_RS08690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EZJ17_RS08715	COG1643	Atp-dependent helicase
EZJ17_RS08725	COG2195	Cleaves the N-terminal amino acid of tripeptides
EZJ17_RS08730	COG1113	amino acid transport
EZJ17_RS08740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EZJ17_RS08760	COG2885	chlorophyll binding
EZJ17_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
EZJ17_RS08780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EZJ17_RS08790	COG1538	Outer membrane efflux protein
EZJ17_RS08795	COG1966	Carbon starvation protein
EZJ17_RS08800	COG2879	small protein
EZJ17_RS08810	COG2226	methyltransferase
EZJ17_RS08815	COG0488	(ABC) transporter
EZJ17_RS08880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EZJ17_RS08880	COG2755	lipolytic protein G-D-S-L family
EZJ17_RS08900	COG1426	Protein conserved in bacteria
EZJ17_RS08915	COG0105	UTP biosynthetic process
EZJ17_RS08925	COG0730	response to heat
EZJ17_RS08930	COG1183	phosphatidylcholine synthase activity
EZJ17_RS08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EZJ17_RS08975	COG1192	Involved in chromosome partitioning
EZJ17_RS08985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EZJ17_RS09010	COG1607	acyl-coa hydrolase
EZJ17_RS09025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EZJ17_RS09075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EZJ17_RS09080	COG0569	domain protein
EZJ17_RS09090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EZJ17_RS09090	COG0678	peroxiredoxin activity
EZJ17_RS09110	COG1739	Uncharacterized protein family UPF0029
EZJ17_RS09120	COG2086	electron transfer activity
EZJ17_RS09125	COG0859	PFAM glycosyl transferase family 9
EZJ17_RS09135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EZJ17_RS09160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EZJ17_RS09170	COG0778	Nitroreductase
EZJ17_RS09185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EZJ17_RS09190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EZJ17_RS09195	COG1137	ATPase activity
EZJ17_RS09220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EZJ17_RS09235	COG2354	Protein conserved in bacteria
EZJ17_RS09265	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EZJ17_RS09270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EZJ17_RS09285	COG0583	DNA-binding transcription factor activity
EZJ17_RS09295	COG2226	methyltransferase
EZJ17_RS09325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EZJ17_RS09330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EZJ17_RS09350	COG0662	Cupin 2, conserved barrel domain protein
EZJ17_RS09360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EZJ17_RS09370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EZJ17_RS09370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EZJ17_RS09375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EZJ17_RS09380	COG2916	Histone family protein nucleoid-structuring protein H-NS
EZJ17_RS09480	COG2841	Protein conserved in bacteria
EZJ17_RS09485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EZJ17_RS09490	COG0511	ligase activity, forming carbon-carbon bonds
EZJ17_RS09495	COG0439	Biotin carboxylase
EZJ17_RS09500	COG0616	signal peptide processing
EZJ17_RS09500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EZJ17_RS09520	COG0758	DNA mediated transformation
EZJ17_RS09520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EZJ17_RS09525	COG2867	negative regulation of translational initiation
EZJ17_RS09535	COG0210	DNA helicase
EZJ17_RS09550	COG0489	protein tyrosine kinase activity
EZJ17_RS09565	COG0745	RESPONSE REGULATOR receiver
EZJ17_RS09580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EZJ17_RS09610	COG1289	transmembrane transporter activity
EZJ17_RS09615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EZJ17_RS09880	COG0270	DNA (cytosine-5-)-methyltransferase activity
EZJ17_RS09895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EZJ17_RS09900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EZJ17_RS09915	COG0805	protein transport
EZJ17_RS09940	COG4969	Belongs to the N-Me-Phe pilin family
EZJ17_RS09950	COG1132	(ABC) transporter
EZJ17_RS09960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EZJ17_RS10010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EZJ17_RS10130	COG3504	Conjugal transfer protein
EZJ17_RS10135	COG3701	Conjugal transfer protein
EZJ17_RS10140	COG3451	type IV secretory pathway VirB4
EZJ17_RS10155	COG4962	Type ii secretion system protein e
EZJ17_RS10165	COG0629	single-stranded DNA binding
EZJ17_RS10195	COG2184	nucleotidyltransferase activity