locus-tag	class	description
FGE20_RS00015	COG5658	integral membrane protein
FGE20_RS00020	COG0640	Transcriptional regulator
FGE20_RS00045	COG4974	Belongs to the 'phage' integrase family
FGE20_RS00060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGE20_RS00065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGE20_RS00070	COG0612	Peptidase, M16
FGE20_RS00080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGE20_RS00085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGE20_RS00090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGE20_RS00120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGE20_RS00125	COG1266	CAAX protease self-immunity
FGE20_RS00140	COG1234	tRNA 3'-trailer cleavage
FGE20_RS00145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGE20_RS00160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGE20_RS00165	COG0077	Prephenate dehydratase
FGE20_RS00170	COG0366	Alpha amylase catalytic
FGE20_RS00180	COG1082	Xylose isomerase domain protein TIM barrel
FGE20_RS00190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FGE20_RS00195	COG4206	TonB-dependent receptor
FGE20_RS00195	COG1629	transport
FGE20_RS00200	COG1506	peptidase
FGE20_RS00210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGE20_RS00215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGE20_RS00225	COG2076	Multidrug Resistance protein
FGE20_RS00240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGE20_RS00245	COG0405	Gamma-glutamyltransferase
FGE20_RS00250	COG0006	proline dipeptidase activity
FGE20_RS00260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FGE20_RS00265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE20_RS00270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGE20_RS00275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE20_RS00280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGE20_RS00280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FGE20_RS00285	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE20_RS00290	COG1078	dGTPase activity
FGE20_RS00300	COG0513	Belongs to the DEAD box helicase family
FGE20_RS00315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE20_RS00325	COG1959	2 iron, 2 sulfur cluster binding
FGE20_RS00330	COG2151	metal-sulfur cluster biosynthetic enzyme
FGE20_RS00345	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FGE20_RS00360	COG2824	Alkylphosphonate utilization operon protein PhnA
FGE20_RS00365	COG1981	membrane
FGE20_RS00375	COG1702	phosphate starvation-inducible protein PhoH
FGE20_RS00380	COG1301	dicarboxylic acid transport
FGE20_RS00385	COG0156	8-amino-7-oxononanoate synthase activity
FGE20_RS00395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGE20_RS00400	COG0506	proline dehydrogenase activity
FGE20_RS00405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGE20_RS00420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGE20_RS00425	COG1968	undecaprenyl-diphosphatase activity
FGE20_RS00435	COG2177	Part of the ABC transporter FtsEX involved in
FGE20_RS00440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGE20_RS00450	COG1575	Belongs to the MenA family. Type 1 subfamily
FGE20_RS00455	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FGE20_RS00465	COG2183	response to ionizing radiation
FGE20_RS00465	COG0539	negative regulation of cytoplasmic translation
FGE20_RS00475	COG0321	lipoyl(octanoyl) transferase activity
FGE20_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE20_RS00500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGE20_RS00500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGE20_RS00515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGE20_RS00530	COG2003	Belongs to the UPF0758 family
FGE20_RS00540	COG1136	(ABC) transporter
FGE20_RS00550	COG0823	Involved in the tonB-independent uptake of proteins
FGE20_RS00550	COG1506	peptidase
FGE20_RS00575	COG2270	Major facilitator Superfamily
FGE20_RS00580	COG0183	Belongs to the thiolase family
FGE20_RS00585	COG2211	Major facilitator Superfamily
FGE20_RS00595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FGE20_RS00625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS00625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS00635	COG0572	uridine kinase
FGE20_RS00640	COG2949	membrane
FGE20_RS00650	COG3118	belongs to the thioredoxin family
FGE20_RS00670	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGE20_RS00670	COG1024	Enoyl-CoA hydratase
FGE20_RS00675	COG0183	Belongs to the thiolase family
FGE20_RS00680	COG1960	acyl-CoA dehydrogenase activity
FGE20_RS00685	COG1295	ribonuclease BN
FGE20_RS00690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGE20_RS00715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGE20_RS00720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGE20_RS00740	COG4654	Cytochrome c, class I
FGE20_RS00750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FGE20_RS00760	COG1959	2 iron, 2 sulfur cluster binding
FGE20_RS00780	COG1522	sequence-specific DNA binding
FGE20_RS00790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGE20_RS00800	COG0009	L-threonylcarbamoyladenylate synthase
FGE20_RS00805	COG3022	response to hydroperoxide
FGE20_RS00810	COG2890	protein-(glutamine-N5) methyltransferase activity
FGE20_RS00835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGE20_RS00840	COG0563	adenylate kinase activity
FGE20_RS00845	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FGE20_RS00850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGE20_RS00850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGE20_RS00855	COG1216	Glycosyl transferase, family 2
FGE20_RS00875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FGE20_RS00880	COG4677	pectinesterase activity
FGE20_RS00885	COG0105	UTP biosynthetic process
FGE20_RS00890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FGE20_RS00895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGE20_RS00900	COG2204	response regulator
FGE20_RS00905	COG0534	Mate efflux family protein
FGE20_RS00915	COG0813	purine-nucleoside phosphorylase activity
FGE20_RS00925	COG0519	Catalyzes the synthesis of GMP from XMP
FGE20_RS00930	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGE20_RS00945	COG0066	3-isopropylmalate dehydratase activity
FGE20_RS00950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGE20_RS00955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGE20_RS00965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGE20_RS00970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGE20_RS00975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGE20_RS00980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGE20_RS00985	COG0673	inositol 2-dehydrogenase activity
FGE20_RS01010	COG0022	dehydrogenase e1 component
FGE20_RS01030	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FGE20_RS01040	COG0589	response to stress
FGE20_RS01040	COG0475	glutathione-regulated potassium exporter activity
FGE20_RS01055	COG0702	epimerase
FGE20_RS01060	COG4206	TonB-dependent receptor
FGE20_RS01060	COG1629	transport
FGE20_RS01080	COG1194	a g-specific adenine glycosylase
FGE20_RS01085	COG0776	regulation of translation
FGE20_RS01090	COG1530	ribonuclease E activity
FGE20_RS01095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGE20_RS01125	COG4716	Myosin-crossreactive antigen
FGE20_RS01165	COG1629	transport
FGE20_RS01200	COG0463	Glycosyl transferase, family 2
FGE20_RS01210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGE20_RS01220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FGE20_RS01230	COG0386	Belongs to the glutathione peroxidase family
FGE20_RS01235	COG5002	protein histidine kinase activity
FGE20_RS01240	COG0745	RESPONSE REGULATOR receiver
FGE20_RS01260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGE20_RS01265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGE20_RS01365	COG3279	Response regulator of the LytR AlgR family
FGE20_RS01370	COG3275	phosphorelay sensor kinase activity
FGE20_RS01410	COG4974	Belongs to the 'phage' integrase family
FGE20_RS01425	COG1104	cysteine desulfurase activity
FGE20_RS01445	COG0277	FAD linked oxidase domain protein
FGE20_RS01450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FGE20_RS01455	COG2885	chlorophyll binding
FGE20_RS01475	COG0681	Belongs to the peptidase S26 family
FGE20_RS01480	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGE20_RS01490	COG1475	DNA binding
FGE20_RS01495	COG1192	Involved in chromosome partitioning
FGE20_RS01505	COG3956	TIGRFAM MazG family protein
FGE20_RS01510	COG0456	acetyltransferase
FGE20_RS01520	COG0542	response to heat
FGE20_RS01535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE20_RS01535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE20_RS01555	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGE20_RS01560	COG1024	Enoyl-CoA hydratase
FGE20_RS01565	COG2151	metal-sulfur cluster biosynthetic enzyme
FGE20_RS01575	COG3460	Phenylacetate-CoA oxygenase
FGE20_RS01580	COG3396	Phenylacetate-CoA oxygenase
FGE20_RS01585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGE20_RS01590	COG1115	amino acid carrier protein
FGE20_RS01595	COG0018	arginyl-trna synthetase
FGE20_RS01605	COG0321	lipoyl(octanoyl) transferase activity
FGE20_RS01605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FGE20_RS01620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGE20_RS01640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGE20_RS01650	COG1595	DNA-templated transcription, initiation
FGE20_RS01665	COG1446	asparaginase
FGE20_RS01730	COG0233	cytoplasmic translational termination
FGE20_RS01735	COG0528	UMP kinase activity
FGE20_RS01780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGE20_RS01810	COG3608	succinylglutamate desuccinylase aspartoacylase
FGE20_RS01815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGE20_RS01835	COG0183	Belongs to the thiolase family
FGE20_RS01840	COG2030	dehydratase
FGE20_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
FGE20_RS01860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGE20_RS01865	COG0196	riboflavin kinase activity
FGE20_RS01870	COG4145	pantothenate transmembrane transporter activity
FGE20_RS01875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGE20_RS01880	COG2137	regulation of response to DNA damage stimulus
FGE20_RS01885	COG0668	transmembrane transport
FGE20_RS01890	COG3250	beta-galactosidase activity
FGE20_RS01905	COG0009	L-threonylcarbamoyladenylate synthase
FGE20_RS01920	COG0492	ferredoxin-NADP+ reductase activity
FGE20_RS01925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGE20_RS01930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGE20_RS01935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGE20_RS01940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGE20_RS01945	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGE20_RS01950	COG0356	it plays a direct role in the translocation of protons across the membrane
FGE20_RS01955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGE20_RS01960	COG0513	Belongs to the DEAD box helicase family
FGE20_RS01985	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FGE20_RS01995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGE20_RS02010	COG0517	IMP dehydrogenase activity
FGE20_RS02010	COG0617	tRNA 3'-terminal CCA addition
FGE20_RS02010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGE20_RS02020	COG4206	TonB-dependent receptor
FGE20_RS02020	COG1629	transport
FGE20_RS02025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGE20_RS02030	COG2070	2-Nitropropane dioxygenase
FGE20_RS02035	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGE20_RS02045	COG0242	peptide deformylase activity
FGE20_RS02050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGE20_RS02055	COG0408	coproporphyrinogen oxidase activity
FGE20_RS02065	COG2252	PERMEase
FGE20_RS02080	COG1114	Component of the transport system for branched-chain amino acids
FGE20_RS02105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGE20_RS02130	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE20_RS02135	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE20_RS02140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE20_RS02145	COG0649	NAD binding
FGE20_RS02150	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FGE20_RS02155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FGE20_RS02165	COG1034	ATP synthesis coupled electron transport
FGE20_RS02170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGE20_RS02175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE20_RS02180	COG0839	Belongs to the complex I subunit 6 family
FGE20_RS02185	COG0713	ATP synthesis coupled electron transport
FGE20_RS02190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FGE20_RS02195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGE20_RS02200	COG1007	ATP synthesis coupled electron transport
FGE20_RS02220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGE20_RS02225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FGE20_RS02235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FGE20_RS02240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FGE20_RS02245	COG4771	TonB-dependent receptor
FGE20_RS02270	COG0156	8-amino-7-oxononanoate synthase activity
FGE20_RS02325	COG0492	ferredoxin-NADP+ reductase activity
FGE20_RS02330	COG1160	GTP binding
FGE20_RS02335	COG1137	ATPase activity
FGE20_RS02340	COG2096	Adenosyltransferase
FGE20_RS02350	COG1185	polyribonucleotide nucleotidyltransferase activity
FGE20_RS02355	COG3781	membrane
FGE20_RS02360	COG0025	NhaP-type Na H and K H
FGE20_RS02390	COG2207	Transcriptional regulator
FGE20_RS02435	COG0671	phosphoesterase, PA-phosphatase related
FGE20_RS02440	COG2814	Major facilitator Superfamily
FGE20_RS02450	COG0017	Asparaginyl-tRNA synthetase
FGE20_RS02455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGE20_RS02465	COG1289	transmembrane transporter activity
FGE20_RS02470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGE20_RS02475	COG1253	flavin adenine dinucleotide binding
FGE20_RS02480	COG1007	ATP synthesis coupled electron transport
FGE20_RS02495	COG0367	asparagine synthase
FGE20_RS02510	COG0006	proline dipeptidase activity
FGE20_RS02515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FGE20_RS02550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE20_RS02550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE20_RS02565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGE20_RS02615	COG4974	Belongs to the 'phage' integrase family
FGE20_RS02625	COG0443	Heat shock 70 kDa protein
FGE20_RS02630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGE20_RS02635	COG0248	Ppx GppA phosphatase
FGE20_RS02640	COG1132	(ABC) transporter
FGE20_RS02650	COG0101	tRNA pseudouridine synthase activity
FGE20_RS02675	COG0612	Peptidase, M16
FGE20_RS02680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGE20_RS02680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGE20_RS02690	COG1136	(ABC) transporter
FGE20_RS02715	COG4717	serine-type aminopeptidase activity
FGE20_RS02720	COG0488	(ABC) transporter
FGE20_RS02730	COG0420	3'-5' exonuclease activity
FGE20_RS02765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGE20_RS02770	COG4774	siderophore transport
FGE20_RS02780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGE20_RS02785	COG0436	Aminotransferase
FGE20_RS02790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGE20_RS02830	COG5002	protein histidine kinase activity
FGE20_RS02835	COG0745	RESPONSE REGULATOR receiver
FGE20_RS02870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGE20_RS02875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGE20_RS02885	COG0028	Belongs to the TPP enzyme family
FGE20_RS02890	COG0129	dihydroxy-acid dehydratase activity
FGE20_RS02915	COG0525	valine-tRNA ligase activity
FGE20_RS02935	COG1418	mRNA catabolic process
FGE20_RS02970	COG0489	protein tyrosine kinase activity
FGE20_RS02975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FGE20_RS02990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE20_RS02995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGE20_RS03005	COG1040	competence protein
FGE20_RS03010	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGE20_RS03020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE20_RS03025	COG0720	synthase
FGE20_RS03035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGE20_RS03070	COG0280	phosphate acetyltransferase
FGE20_RS03070	COG0281	malic enzyme
FGE20_RS03080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGE20_RS03085	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGE20_RS03090	COG0515	serine threonine protein kinase
FGE20_RS03095	COG0564	pseudouridine synthase activity
FGE20_RS03110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGE20_RS03130	COG1629	transport
FGE20_RS03135	COG0205	6-phosphofructokinase activity
FGE20_RS03145	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FGE20_RS03150	COG1301	dicarboxylic acid transport
FGE20_RS03155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGE20_RS03160	COG2205	protein histidine kinase activity
FGE20_RS03160	COG0784	Response regulator, receiver
FGE20_RS03160	COG5002	protein histidine kinase activity
FGE20_RS03185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGE20_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS03210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGE20_RS03215	COG0194	GDP metabolic process
FGE20_RS03220	COG1561	YicC-like family, N-terminal region
FGE20_RS03225	COG1663	tetraacyldisaccharide 4'-kinase activity
FGE20_RS03235	COG1119	ATPase activity
FGE20_RS03240	COG3250	beta-galactosidase activity
FGE20_RS03245	COG0706	membrane insertase activity
FGE20_RS03250	COG0504	CTP synthase activity
FGE20_RS03255	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FGE20_RS03270	COG0326	Molecular chaperone. Has ATPase activity
FGE20_RS03275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGE20_RS03295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGE20_RS03305	COG0010	Belongs to the arginase family
FGE20_RS03310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGE20_RS03315	COG0589	response to stress
FGE20_RS03330	COG1183	phosphatidylcholine synthase activity
FGE20_RS03360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGE20_RS03370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FGE20_RS03375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FGE20_RS03390	COG0646	methionine synthase
FGE20_RS03390	COG1410	methionine synthase
FGE20_RS03405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGE20_RS03425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGE20_RS03440	COG1381	Involved in DNA repair and RecF pathway recombination
FGE20_RS03450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGE20_RS03455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGE20_RS03465	COG0509	glycine decarboxylation via glycine cleavage system
FGE20_RS03475	COG0632	four-way junction helicase activity
FGE20_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FGE20_RS03540	COG2873	o-acetylhomoserine
FGE20_RS03545	COG1834	amidinotransferase
FGE20_RS03555	COG0148	phosphopyruvate hydratase activity
FGE20_RS03570	COG0203	ribosomal protein L17
FGE20_RS03575	COG0202	RNA polymerase activity
FGE20_RS03580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGE20_RS03585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGE20_RS03590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGE20_RS03595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGE20_RS03600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGE20_RS03610	COG0200	Binds to the 23S rRNA
FGE20_RS03615	COG1841	ribosomal large subunit assembly
FGE20_RS03620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGE20_RS03625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGE20_RS03630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGE20_RS03635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGE20_RS03640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGE20_RS03645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGE20_RS03650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGE20_RS03655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGE20_RS03660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGE20_RS03665	COG0255	Belongs to the universal ribosomal protein uL29 family
FGE20_RS03670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGE20_RS03675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGE20_RS03680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGE20_RS03685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGE20_RS03690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGE20_RS03695	COG0089	rRNA binding
FGE20_RS03700	COG0088	Forms part of the polypeptide exit tunnel
FGE20_RS03705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGE20_RS03735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGE20_RS03740	COG0004	ammonium transporteR
FGE20_RS03745	COG0783	Belongs to the Dps family
FGE20_RS03750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGE20_RS03755	COG0049	tRNA binding
FGE20_RS03760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGE20_RS03765	COG0051	transcription antitermination factor activity, RNA binding
FGE20_RS03820	COG0826	peptidase U32
FGE20_RS03830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGE20_RS03855	COG4771	TonB-dependent receptor
FGE20_RS03870	COG1629	transport
FGE20_RS03880	COG4771	TonB-dependent receptor
FGE20_RS03890	COG0251	oxidation-reduction process
FGE20_RS03910	COG0268	Binds directly to 16S ribosomal RNA
FGE20_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS03935	COG1312	Catalyzes the dehydration of D-mannonate
FGE20_RS03940	COG1904	glucuronate isomerase
FGE20_RS03945	COG1609	Transcriptional regulator
FGE20_RS03955	COG0254	rRNA binding
FGE20_RS03970	COG0300	oxidoreductase activity
FGE20_RS03975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FGE20_RS03990	COG1388	LysM domain
FGE20_RS03990	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGE20_RS03995	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FGE20_RS04005	COG2224	Isocitrate lyase
FGE20_RS04010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGE20_RS04020	COG0823	Involved in the tonB-independent uptake of proteins
FGE20_RS04020	COG1506	peptidase
FGE20_RS04030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGE20_RS04040	COG4772	TonB-dependent receptor
FGE20_RS04055	COG0778	Nitroreductase
FGE20_RS04065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGE20_RS04080	COG1082	Xylose isomerase domain protein TIM barrel
FGE20_RS04090	COG1611	Belongs to the LOG family
FGE20_RS04095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGE20_RS04120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGE20_RS04125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGE20_RS04160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGE20_RS04165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGE20_RS04170	COG0583	DNA-binding transcription factor activity
FGE20_RS04180	COG1024	Enoyl-CoA hydratase
FGE20_RS04190	COG4974	Belongs to the 'phage' integrase family
FGE20_RS04195	COG2816	NAD+ diphosphatase activity
FGE20_RS04210	COG3118	belongs to the thioredoxin family
FGE20_RS04220	COG0019	diaminopimelate decarboxylase activity
FGE20_RS04225	COG2176	DNA-directed DNA polymerase activity
FGE20_RS04230	COG0433	COG0433 Predicted ATPase
FGE20_RS04240	COG0811	peptide transport
FGE20_RS04245	COG0848	biopolymer transport protein
FGE20_RS04275	COG2166	iron-sulfur cluster assembly
FGE20_RS04280	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS04285	COG0542	response to heat
FGE20_RS04300	COG0758	DNA mediated transformation
FGE20_RS04315	COG0606	chelatase, subunit chli
FGE20_RS04325	COG0662	Cupin 2, conserved barrel domain protein
FGE20_RS04325	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FGE20_RS04345	COG2151	metal-sulfur cluster biosynthetic enzyme
FGE20_RS04355	COG1770	oligopeptidase
FGE20_RS04370	COG1216	Glycosyl transferase, family 2
FGE20_RS04380	COG0343	queuine tRNA-ribosyltransferase activity
FGE20_RS04395	COG0799	negative regulation of ribosome biogenesis
FGE20_RS04400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGE20_RS04410	COG4589	Belongs to the CDS family
FGE20_RS04415	COG0688	phosphatidylethanolamine metabolic process
FGE20_RS04420	COG2321	neutral zinc metallopeptidase
FGE20_RS04425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE20_RS04430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGE20_RS04435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FGE20_RS04445	COG2081	HI0933 family
FGE20_RS04460	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGE20_RS04495	COG2234	aminopeptidase activity
FGE20_RS04495	COG4935	Belongs to the peptidase S8 family
FGE20_RS04500	COG0482	sulfurtransferase activity
FGE20_RS04510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGE20_RS04525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGE20_RS04550	COG0772	Belongs to the SEDS family
FGE20_RS04555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGE20_RS04565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FGE20_RS04565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FGE20_RS04580	COG0387	Pfam Sodium calcium exchanger
FGE20_RS04585	COG3591	Belongs to the peptidase S1B family
FGE20_RS04610	COG1610	YqeY-like protein
FGE20_RS04615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGE20_RS04630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGE20_RS04635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGE20_RS04645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGE20_RS04650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGE20_RS04655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGE20_RS04660	COG0768	penicillin binding
FGE20_RS04670	COG0275	rRNA processing
FGE20_RS04675	COG2001	Belongs to the MraZ family
FGE20_RS04685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGE20_RS04705	COG4206	TonB-dependent receptor
FGE20_RS04715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGE20_RS04720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGE20_RS04745	COG3033	Beta-eliminating lyase
FGE20_RS04795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGE20_RS04800	COG0719	Fe-S assembly protein
FGE20_RS04805	COG0396	ATPase activity
FGE20_RS04810	COG0719	Fe-S assembly protein
FGE20_RS04815	COG0316	Belongs to the HesB IscA family
FGE20_RS04830	COG0556	nucleotide-excision repair
FGE20_RS04840	COG4152	abc transporter atp-binding protein
FGE20_RS04845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGE20_RS04850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGE20_RS04865	COG1774	PSP1 C-terminal conserved region
FGE20_RS04875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGE20_RS04880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FGE20_RS04915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGE20_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS04930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGE20_RS04940	COG1435	thymidine kinase activity
FGE20_RS04955	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGE20_RS04960	COG0445	tRNA wobble uridine modification
FGE20_RS04970	COG0126	phosphoglycerate kinase activity
FGE20_RS04975	COG0698	ribose 5-phosphate isomerase
FGE20_RS04980	COG0557	exoribonuclease II activity
FGE20_RS04990	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGE20_RS04995	COG0792	nuclease activity
FGE20_RS05000	COG4221	oxidoreductase activity
FGE20_RS05005	COG1214	PFAM Peptidase M22, glycoprotease
FGE20_RS05010	COG0659	secondary active sulfate transmembrane transporter activity
FGE20_RS05025	COG0750	zinc metalloprotease
FGE20_RS05055	COG0481	GTPase activity
FGE20_RS05070	COG1595	DNA-templated transcription, initiation
FGE20_RS05080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGE20_RS05085	COG0424	maF-like protein
FGE20_RS05100	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FGE20_RS05110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGE20_RS05135	COG0423	glycine-tRNA ligase activity
FGE20_RS05140	COG2733	membrane
FGE20_RS05145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGE20_RS05175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FGE20_RS05190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGE20_RS05200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGE20_RS05210	COG0700	Nucleoside recognition
FGE20_RS05220	COG1505	serine-type exopeptidase activity
FGE20_RS05255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGE20_RS05270	COG0363	glucosamine-6-phosphate deaminase activity
FGE20_RS05290	COG3275	phosphorelay sensor kinase activity
FGE20_RS05300	COG3279	Response regulator of the LytR AlgR family
FGE20_RS05315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE20_RS05325	COG0653	protein targeting
FGE20_RS05330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGE20_RS05350	COG0594	ribonuclease P activity
FGE20_RS05355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FGE20_RS05360	COG0084	hydrolase, TatD family'
FGE20_RS05380	COG2814	Major facilitator Superfamily
FGE20_RS05385	COG0590	tRNA wobble adenosine to inosine editing
FGE20_RS05395	COG0791	NLP P60 protein
FGE20_RS05400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGE20_RS05405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGE20_RS05430	COG0497	DNA recombination
FGE20_RS05435	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS05435	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS05455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGE20_RS05465	COG0110	maltose O-acetyltransferase activity
FGE20_RS05480	COG2181	nitrate reductase activity
FGE20_RS05480	COG0247	lactate metabolic process
FGE20_RS05485	COG0247	lactate metabolic process
FGE20_RS05485	COG2181	nitrate reductase activity
FGE20_RS05490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGE20_RS05495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE20_RS05500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGE20_RS05505	COG0166	Belongs to the GPI family
FGE20_RS05510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGE20_RS05515	COG0602	queuosine metabolic process
FGE20_RS05520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGE20_RS05525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGE20_RS05565	COG0348	domain, Protein
FGE20_RS05600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGE20_RS05605	COG0564	pseudouridine synthase activity
FGE20_RS05615	COG0137	argininosuccinate synthase activity
FGE20_RS05620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGE20_RS05630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGE20_RS05635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGE20_RS05640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGE20_RS05650	COG0165	Argininosuccinate lyase
FGE20_RS05655	COG1522	sequence-specific DNA binding
FGE20_RS05660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FGE20_RS05690	COG1607	acyl-coa hydrolase
FGE20_RS05695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGE20_RS05700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FGE20_RS05715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE20_RS05720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE20_RS05720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE20_RS05750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGE20_RS05770	COG1846	Transcriptional regulator
FGE20_RS05785	COG0437	4 iron, 4 sulfur cluster binding
FGE20_RS05825	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGE20_RS05845	COG1132	(ABC) transporter
FGE20_RS05870	COG1011	Hydrolase
FGE20_RS05875	COG0180	Tryptophanyl-tRNA synthetase
FGE20_RS05880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGE20_RS05890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGE20_RS05905	COG1442	glycosyl transferase family 8
FGE20_RS05905	COG1216	Glycosyl transferase, family 2
FGE20_RS05915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGE20_RS05925	COG3206	protein involved in exopolysaccharide biosynthesis
FGE20_RS05925	COG0489	protein tyrosine kinase activity
FGE20_RS05940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGE20_RS06015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGE20_RS06020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGE20_RS06025	COG2884	Cell division ATP-binding protein ftsE
FGE20_RS06030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGE20_RS06035	COG5000	phosphorelay sensor kinase activity
FGE20_RS06040	COG0307	riboflavin synthase, alpha
FGE20_RS06045	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGE20_RS06055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGE20_RS06060	COG0511	ligase activity, forming carbon-carbon bonds
FGE20_RS06065	COG0439	Biotin carboxylase
FGE20_RS06075	COG3275	phosphorelay sensor kinase activity
FGE20_RS06080	COG0577	efflux transmembrane transporter activity
FGE20_RS06080	COG1136	(ABC) transporter
FGE20_RS06085	COG1136	(ABC) transporter
FGE20_RS06090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE20_RS06100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGE20_RS06105	COG0463	Glycosyl transferase, family 2
FGE20_RS06130	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS06145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGE20_RS06150	COG0825	malonyl-CoA metabolic process
FGE20_RS06165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGE20_RS06180	COG0516	GMP reductase activity
FGE20_RS06180	COG0517	IMP dehydrogenase activity
FGE20_RS06185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGE20_RS06200	COG0052	Belongs to the universal ribosomal protein uS2 family
FGE20_RS06205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGE20_RS06210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGE20_RS06220	COG1703	isobutyryl-CoA mutase activity
FGE20_RS06220	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS06220	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FGE20_RS06230	COG0215	cysteine-tRNA ligase activity
FGE20_RS06235	COG0302	gtp cyclohydrolase
FGE20_RS06240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGE20_RS06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE20_RS06250	COG0571	ribonuclease III activity
FGE20_RS06260	COG0469	pyruvate kinase activity
FGE20_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS06270	COG2333	competence protein COMEC
FGE20_RS06270	COG0658	competence protein
FGE20_RS06280	COG1053	succinate dehydrogenase
FGE20_RS06285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGE20_RS06295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGE20_RS06310	COG0237	dephospho-CoA kinase activity
FGE20_RS06315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE20_RS06320	COG2255	four-way junction helicase activity
FGE20_RS06325	COG1228	amidohydrolase
FGE20_RS06330	COG0010	Belongs to the arginase family
FGE20_RS06335	COG1012	belongs to the aldehyde dehydrogenase family
FGE20_RS06370	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE20_RS06370	COG0596	Alpha beta hydrolase
FGE20_RS06380	COG0037	tRNA processing
FGE20_RS06390	COG0791	NLP P60 protein
FGE20_RS06395	COG1519	Transferase
FGE20_RS06405	COG0495	leucyl-tRNA aminoacylation
FGE20_RS06445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FGE20_RS06460	COG1132	(ABC) transporter
FGE20_RS06465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGE20_RS06505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGE20_RS06515	COG0328	RNA-DNA hybrid ribonuclease activity
FGE20_RS06520	COG0305	Participates in initiation and elongation during chromosome replication
FGE20_RS06530	COG0288	reversible hydration of carbon dioxide
FGE20_RS06535	COG0193	aminoacyl-tRNA hydrolase activity
FGE20_RS06540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGE20_RS06560	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS06570	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS06590	COG1215	transferase activity, transferring glycosyl groups
FGE20_RS06600	COG1216	Glycosyl transferase, family 2
FGE20_RS06600	COG1442	glycosyl transferase family 8
FGE20_RS06605	COG1216	Glycosyl transferase, family 2
FGE20_RS06615	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS06675	COG0779	Required for maturation of 30S ribosomal subunits
FGE20_RS06680	COG0195	Participates in both transcription termination and antitermination
FGE20_RS06685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGE20_RS06690	COG4771	TonB-dependent receptor
FGE20_RS06700	COG4771	TonB-dependent receptor
FGE20_RS06710	COG4771	TonB-dependent receptor
FGE20_RS06730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGE20_RS06735	COG0081	regulation of translation
FGE20_RS06740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGE20_RS06745	COG0222	ribosome binding
FGE20_RS06760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGE20_RS06770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGE20_RS06780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGE20_RS06790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGE20_RS06795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FGE20_RS06800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FGE20_RS06800	COG0822	iron-sulfur transferase activity
FGE20_RS06800	COG2906	2 iron, 2 sulfur cluster binding
FGE20_RS06805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGE20_RS06810	COG0616	signal peptide processing
FGE20_RS06815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGE20_RS06815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGE20_RS06820	COG2885	chlorophyll binding
FGE20_RS06835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGE20_RS06855	COG0339	signal peptide processing
FGE20_RS06865	COG3250	beta-galactosidase activity
FGE20_RS06875	COG4771	TonB-dependent receptor
FGE20_RS06880	COG0702	epimerase
FGE20_RS06920	COG3781	membrane
FGE20_RS06925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGE20_RS06945	COG0322	excinuclease ABC activity
FGE20_RS06950	COG1074	ATP-dependent DNA helicase activity
FGE20_RS06955	COG1027	Aspartate ammonia-lyase
FGE20_RS06960	COG0252	asparaginase activity
FGE20_RS06975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGE20_RS06980	COG4974	Belongs to the 'phage' integrase family
FGE20_RS06985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGE20_RS07010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGE20_RS07055	COG2274	protein secretion by the type I secretion system
FGE20_RS07065	COG0300	oxidoreductase activity
FGE20_RS07070	COG0488	(ABC) transporter
FGE20_RS07075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGE20_RS07085	COG0217	transcriptional regulatory protein
FGE20_RS07090	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGE20_RS07100	COG0714	Associated with various cellular activities
FGE20_RS07135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGE20_RS07140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGE20_RS07140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FGE20_RS07145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGE20_RS07145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGE20_RS07170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGE20_RS07180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGE20_RS07195	COG0318	PFAM AMP-dependent synthetase and ligase
FGE20_RS07205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGE20_RS07215	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGE20_RS07235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGE20_RS07240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGE20_RS07250	COG0552	protein localization to endoplasmic reticulum
FGE20_RS07275	COG1490	D-aminoacyl-tRNA deacylase activity
FGE20_RS07280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FGE20_RS07285	COG0527	aspartate kinase activity
FGE20_RS07300	COG0085	RNA polymerase activity
FGE20_RS07305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGE20_RS07315	COG0708	Exodeoxyribonuclease III
FGE20_RS07320	COG0456	acetyltransferase
FGE20_RS07325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGE20_RS07330	COG0297	glycogen (starch) synthase activity
FGE20_RS07340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGE20_RS07345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FGE20_RS07370	COG1959	2 iron, 2 sulfur cluster binding
FGE20_RS07375	COG0175	sulfate reduction
FGE20_RS07380	COG0175	sulfate reduction
FGE20_RS07390	COG1045	serine acetyltransferase
FGE20_RS07400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGE20_RS07400	COG1648	precorrin-2 dehydrogenase activity
FGE20_RS07405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGE20_RS07415	COG1648	precorrin-2 dehydrogenase activity
FGE20_RS07415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGE20_RS07425	COG0534	Mate efflux family protein
FGE20_RS07440	COG1678	Uncharacterized ACR, COG1678
FGE20_RS07445	COG0259	pyridoxamine-phosphate oxidase activity
FGE20_RS07455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FGE20_RS07475	COG0022	dehydrogenase e1 component
FGE20_RS07475	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE20_RS07480	COG3158	transport of potassium into the cell
FGE20_RS07495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGE20_RS07510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGE20_RS07515	COG0459	protein refolding
FGE20_RS07520	COG1047	Peptidyl-prolyl cis-trans
FGE20_RS07535	COG1538	Outer membrane efflux protein
FGE20_RS07550	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGE20_RS07560	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS07565	COG1472	Belongs to the glycosyl hydrolase 3 family
FGE20_RS07585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGE20_RS07605	COG4232	protein-disulfide reductase activity
FGE20_RS07620	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FGE20_RS07625	COG0583	DNA-binding transcription factor activity
FGE20_RS07630	COG3104	oligopeptide transport
FGE20_RS07640	COG0095	Lipoate-protein ligase
FGE20_RS07655	COG0228	four-way junction DNA binding
FGE20_RS07660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGE20_RS07675	COG4771	TonB-dependent receptor
FGE20_RS07690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FGE20_RS07695	COG3250	beta-galactosidase activity
FGE20_RS07700	COG0492	ferredoxin-NADP+ reductase activity
FGE20_RS07705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGE20_RS07740	COG0300	oxidoreductase activity
FGE20_RS07820	COG3012	SEC-C Motif Domain Protein
FGE20_RS07825	COG0339	signal peptide processing
FGE20_RS07835	COG0659	secondary active sulfate transmembrane transporter activity
FGE20_RS07865	COG1674	ftsk spoiiie
FGE20_RS07870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGE20_RS07870	COG1333	cytochrome c biogenesis protein
FGE20_RS07875	COG3876	Protein conserved in bacteria
FGE20_RS07890	COG1506	peptidase
FGE20_RS07890	COG0823	Involved in the tonB-independent uptake of proteins
FGE20_RS07895	COG0039	L-malate dehydrogenase activity
FGE20_RS07905	COG3023	N-Acetylmuramoyl-L-alanine amidase
FGE20_RS07940	COG0069	glutamate synthase activity
FGE20_RS07945	COG0484	heat shock protein binding
FGE20_RS07975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FGE20_RS07990	COG2244	polysaccharide biosynthetic process
FGE20_RS08000	COG1216	Glycosyl transferase, family 2
FGE20_RS08000	COG0463	Glycosyl transferase, family 2
FGE20_RS08005	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS08030	COG0438	transferase activity, transferring glycosyl groups
FGE20_RS08035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGE20_RS08040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGE20_RS08050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGE20_RS08085	COG0346	lactoylglutathione lyase activity
FGE20_RS08090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGE20_RS08100	COG5297	Belongs to the glycosyl hydrolase family 6
FGE20_RS08100	COG4733	cellulase activity
FGE20_RS08105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGE20_RS08115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGE20_RS08115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGE20_RS08120	COG1739	Uncharacterized protein family UPF0029
FGE20_RS08130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE20_RS08135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGE20_RS08155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGE20_RS08155	COG2207	Transcriptional regulator
FGE20_RS08160	COG0167	dihydroorotate dehydrogenase activity
FGE20_RS08165	COG0702	epimerase
FGE20_RS08175	COG0359	binds to the 23S rRNA
FGE20_RS08180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGE20_RS08185	COG0360	Binds together with S18 to 16S ribosomal RNA
FGE20_RS08200	COG1757	Na H antiporter
FGE20_RS08205	COG0628	permease
FGE20_RS08215	COG1011	Hydrolase
FGE20_RS08230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGE20_RS08235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGE20_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGE20_RS08250	COG3250	beta-galactosidase activity
FGE20_RS08265	COG1187	pseudouridine synthase activity
FGE20_RS08275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGE20_RS08280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGE20_RS08285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGE20_RS08290	COG1085	galactose-1-phosphate uridylyltransferase
FGE20_RS08295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGE20_RS08300	COG2017	converts alpha-aldose to the beta-anomer
FGE20_RS08305	COG0670	Belongs to the BI1 family
FGE20_RS08310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGE20_RS08315	COG0586	Pfam SNARE associated Golgi protein
FGE20_RS08320	COG0358	DNA primase activity
FGE20_RS08350	COG4774	siderophore transport
FGE20_RS08365	COG0577	efflux transmembrane transporter activity
FGE20_RS08365	COG1136	(ABC) transporter
FGE20_RS08375	COG0419	ATPase involved in DNA repair
FGE20_RS08380	COG0626	cystathionine gamma-synthase activity
FGE20_RS08385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGE20_RS08390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGE20_RS08395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGE20_RS08410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGE20_RS08420	COG2207	Transcriptional regulator
FGE20_RS08425	COG2217	Heavy metal translocating P-type atpase
FGE20_RS08455	COG2197	response regulator
FGE20_RS08475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGE20_RS08485	COG1538	Outer membrane efflux protein
FGE20_RS08495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGE20_RS08510	COG4574	serine-type endopeptidase inhibitor activity
FGE20_RS08515	COG0484	heat shock protein binding
FGE20_RS08520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGE20_RS08555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGE20_RS08560	COG3340	Belongs to the peptidase S51 family
FGE20_RS08580	COG0540	Belongs to the ATCase OTCase family
FGE20_RS08585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGE20_RS08595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGE20_RS08640	COG0671	phosphoesterase, PA-phosphatase related
FGE20_RS08665	COG3209	COG3209 Rhs family protein
FGE20_RS08700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGE20_RS08710	COG0567	Dehydrogenase, E1 component
FGE20_RS08715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGE20_RS08720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGE20_RS08720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGE20_RS08780	COG4152	abc transporter atp-binding protein
FGE20_RS08820	COG2354	Protein conserved in bacteria
FGE20_RS08825	COG0022	dehydrogenase e1 component
FGE20_RS08850	COG5434	Belongs to the glycosyl hydrolase 28 family
FGE20_RS08865	COG1546	Belongs to the CinA family
FGE20_RS08865	COG1058	Belongs to the CinA family
FGE20_RS08885	COG0295	cytidine deaminase activity
FGE20_RS08900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGE20_RS08915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGE20_RS08935	COG0442	prolyl-tRNA aminoacylation
FGE20_RS08940	COG0488	(ABC) transporter
FGE20_RS08945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGE20_RS08955	COG2239	Acts as a magnesium transporter
FGE20_RS08970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGE20_RS08980	COG1285	pathogenesis
FGE20_RS08985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGE20_RS09005	COG0149	triose-phosphate isomerase activity
FGE20_RS09010	COG2264	protein methyltransferase activity
FGE20_RS09015	COG3345	alpha-galactosidase
FGE20_RS09045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGE20_RS09070	COG1335	isochorismatase
FGE20_RS09095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGE20_RS09115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGE20_RS09130	COG1215	transferase activity, transferring glycosyl groups
FGE20_RS09140	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FGE20_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS09150	COG3425	synthase
FGE20_RS09155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGE20_RS09160	COG0306	phosphate transporter
FGE20_RS09180	COG3781	membrane
FGE20_RS09230	COG0531	amino acid
FGE20_RS09240	COG2706	6-phosphogluconolactonase activity
FGE20_RS09245	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGE20_RS09260	COG0247	lactate metabolic process
FGE20_RS09265	COG1139	Iron-sulfur cluster binding protein
FGE20_RS09270	COG1556	Lactate utilization protein
FGE20_RS09275	COG0738	Major facilitator superfamily
FGE20_RS09280	COG2721	sulfolactate sulfo-lyase activity
FGE20_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS09290	COG0179	Fumarylacetoacetate (FAA) hydrolase
FGE20_RS09295	COG3254	rhamnose metabolic process
FGE20_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS09325	COG1217	gtp-binding protein TYPA
FGE20_RS09330	COG0070	glutamate synthase
FGE20_RS09330	COG0067	glutamate synthase
FGE20_RS09330	COG0069	glutamate synthase activity
FGE20_RS09340	COG3189	MarR family transcriptional regulator
FGE20_RS09345	COG3015	lipoprotein NlpE involved in copper resistance
FGE20_RS09355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGE20_RS09380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE20_RS09390	COG0714	Associated with various cellular activities
FGE20_RS09410	COG2304	oxidoreductase activity
FGE20_RS09425	COG2095	MarC family integral membrane protein
FGE20_RS09435	COG1169	isochorismate synthase
FGE20_RS09440	COG2050	protein possibly involved in aromatic compounds catabolism
FGE20_RS09475	COG1428	Deoxynucleoside kinase
FGE20_RS09490	COG0592	DNA-directed DNA polymerase activity
FGE20_RS09510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGE20_RS09530	COG0802	atpase or kinase
FGE20_RS09535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGE20_RS09550	COG2356	endonuclease I
FGE20_RS09555	COG1960	acyl-CoA dehydrogenase activity
FGE20_RS09575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGE20_RS09590	COG0531	amino acid
FGE20_RS09600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGE20_RS09605	COG0512	Glutamine amidotransferase of anthranilate synthase
FGE20_RS09610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGE20_RS09615	COG0134	indole-3-glycerol-phosphate synthase activity
FGE20_RS09620	COG0135	phosphoribosylanthranilate isomerase activity
FGE20_RS09625	COG0133	tryptophan synthase activity
FGE20_RS09630	COG0159	tryptophan synthase activity
FGE20_RS09635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGE20_RS09640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGE20_RS09700	COG5492	domain, Protein
FGE20_RS09705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGE20_RS09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGE20_RS09715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGE20_RS09735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGE20_RS09745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGE20_RS09750	COG1595	DNA-templated transcription, initiation
FGE20_RS09760	COG1408	metallophosphoesterase
FGE20_RS09765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGE20_RS09775	COG2226	methyltransferase
FGE20_RS09795	COG1418	mRNA catabolic process
FGE20_RS09830	COG3250	beta-galactosidase activity
FGE20_RS09850	COG0579	oxidoreductase
FGE20_RS09855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGE20_RS09865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGE20_RS09875	COG2022	thiamine diphosphate biosynthetic process
FGE20_RS09880	COG0352	thiamine-phosphate diphosphorylase activity
FGE20_RS09885	COG0351	phosphomethylpyrimidine kinase
FGE20_RS09905	COG0745	RESPONSE REGULATOR receiver
FGE20_RS09910	COG5002	protein histidine kinase activity
FGE20_RS09915	COG1368	sulfuric ester hydrolase activity
FGE20_RS09925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGE20_RS09930	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FGE20_RS09950	COG1803	Methylglyoxal synthase
FGE20_RS09965	COG0450	alkyl hydroperoxide reductase
FGE20_RS09975	COG0668	transmembrane transport
FGE20_RS09980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGE20_RS09985	COG0596	Alpha beta hydrolase
FGE20_RS09995	COG1022	Amp-dependent synthetase and ligase
FGE20_RS10005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGE20_RS10010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGE20_RS10025	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGE20_RS10030	COG1446	asparaginase
FGE20_RS10040	COG0791	NLP P60 protein
FGE20_RS10045	COG2171	N-acyltransferase activity
FGE20_RS10055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGE20_RS10065	COG0463	Glycosyl transferase, family 2
FGE20_RS10100	COG0084	hydrolase, TatD family'
FGE20_RS10115	COG1760	l-serine dehydratase
FGE20_RS10120	COG0038	chloride channel
FGE20_RS10135	COG0590	tRNA wobble adenosine to inosine editing
FGE20_RS10145	COG0702	epimerase
FGE20_RS10155	COG4115	mRNA cleavage
FGE20_RS10160	COG2161	toxin-antitoxin pair type II binding
FGE20_RS10180	COG1346	cytolysis
FGE20_RS10185	COG1380	Effector of murein hydrolase LrgA
FGE20_RS10190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FGE20_RS10200	COG3590	peptidase
FGE20_RS10220	COG5002	protein histidine kinase activity
FGE20_RS10225	COG0745	RESPONSE REGULATOR receiver
FGE20_RS10235	COG0730	response to heat
FGE20_RS10240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGE20_RS10245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FGE20_RS10250	COG0427	acetyl-CoA hydrolase
FGE20_RS10260	COG4413	Urea transporter
FGE20_RS10280	COG1012	belongs to the aldehyde dehydrogenase family
FGE20_RS10290	COG5212	phosphodiesterase
FGE20_RS10315	COG1943	Transposase
FGE20_RS10350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGE20_RS10360	COG0598	Magnesium transport protein CorA
FGE20_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
FGE20_RS10405	COG3153	acetyltransferase
FGE20_RS10405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGE20_RS10410	COG1960	acyl-CoA dehydrogenase activity
FGE20_RS10440	COG0116	Belongs to the methyltransferase superfamily
FGE20_RS10445	COG0463	Glycosyl transferase, family 2
FGE20_RS10445	COG1216	Glycosyl transferase, family 2
FGE20_RS10460	COG0336	Belongs to the RNA methyltransferase TrmD family
FGE20_RS10470	COG1522	sequence-specific DNA binding
FGE20_RS10475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGE20_RS10485	COG0113	porphobilinogen synthase activity
FGE20_RS10495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGE20_RS10495	COG0284	orotidine-5'-phosphate decarboxylase activity
FGE20_RS10500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FGE20_RS10505	COG3119	arylsulfatase activity
FGE20_RS10515	COG3119	arylsulfatase activity
FGE20_RS10535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGE20_RS10555	COG0436	Aminotransferase
FGE20_RS10560	COG0357	Ribosomal RNA small subunit methyltransferase G
FGE20_RS10575	COG0012	GTP binding
FGE20_RS10580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGE20_RS10590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGE20_RS10605	COG3590	peptidase
FGE20_RS10610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGE20_RS10615	COG1607	acyl-coa hydrolase
FGE20_RS10620	COG0673	inositol 2-dehydrogenase activity
FGE20_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
FGE20_RS10630	COG3118	belongs to the thioredoxin family
FGE20_RS10635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGE20_RS10640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGE20_RS10650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGE20_RS10655	COG3537	Alpha-1,2-mannosidase
FGE20_RS10660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FGE20_RS10660	COG0140	phosphoribosyl-ATP diphosphatase activity
FGE20_RS10665	COG0107	imidazoleglycerol-phosphate synthase activity
FGE20_RS10670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGE20_RS10685	COG0131	Imidazoleglycerol-phosphate dehydratase
FGE20_RS10690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGE20_RS10695	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGE20_RS10700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGE20_RS10720	COG0352	thiamine-phosphate diphosphorylase activity
FGE20_RS10725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FGE20_RS10725	COG0352	thiamine-phosphate diphosphorylase activity
FGE20_RS10725	COG0351	phosphomethylpyrimidine kinase
FGE20_RS10735	COG0793	Belongs to the peptidase S41A family
FGE20_RS10740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FGE20_RS10745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGE20_RS10755	COG1605	Chorismate mutase
FGE20_RS10755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FGE20_RS10760	COG1162	GTPase activity
FGE20_RS10765	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGE20_RS10785	COG3511	phospholipase C
FGE20_RS10790	COG2814	Major facilitator Superfamily
FGE20_RS10805	COG0252	asparaginase activity
FGE20_RS10810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGE20_RS10815	COG2315	Protein conserved in bacteria
FGE20_RS10825	COG1960	acyl-CoA dehydrogenase activity
FGE20_RS10830	COG0187	DNA topoisomerase II activity
FGE20_RS10865	COG0124	histidyl-tRNA synthetase
FGE20_RS10875	COG4152	abc transporter atp-binding protein
FGE20_RS10880	COG1970	mechanosensitive ion channel activity
FGE20_RS10885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGE20_RS10895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGE20_RS10905	COG0335	large ribosomal subunit rRNA binding
FGE20_RS10910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FGE20_RS10915	COG1979	alcohol dehydrogenase
FGE20_RS10930	COG2183	response to ionizing radiation
FGE20_RS10935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGE20_RS10940	COG1522	sequence-specific DNA binding
FGE20_RS10945	COG0697	spore germination
FGE20_RS10965	COG2382	esterase
FGE20_RS10965	COG3507	Belongs to the glycosyl hydrolase 43 family
FGE20_RS10965	COG3693	PFAM glycoside hydrolase, family 10
FGE20_RS10970	COG1012	belongs to the aldehyde dehydrogenase family
FGE20_RS10985	COG2268	Band 7 protein
FGE20_RS10995	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FGE20_RS11015	COG1113	amino acid transport
FGE20_RS11025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGE20_RS11060	COG0629	single-stranded DNA binding
FGE20_RS11065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGE20_RS11065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGE20_RS11070	COG1607	acyl-coa hydrolase
FGE20_RS11075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGE20_RS11125	COG0519	Catalyzes the synthesis of GMP from XMP
FGE20_RS11125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGE20_RS11130	COG0151	Belongs to the GarS family
FGE20_RS11140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGE20_RS11145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGE20_RS11155	COG1741	Belongs to the pirin family
FGE20_RS11175	COG2814	Major facilitator Superfamily
FGE20_RS11185	COG4771	TonB-dependent receptor
FGE20_RS11190	COG0702	epimerase
FGE20_RS11195	COG4771	TonB-dependent receptor
FGE20_RS11200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGE20_RS11215	COG2755	lipolytic protein G-D-S-L family
FGE20_RS11215	COG0657	acetylesterase activity
FGE20_RS11240	COG1363	Peptidase, m42
FGE20_RS11260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGE20_RS11260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FGE20_RS11265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGE20_RS11270	COG0460	homoserine dehydrogenase
FGE20_RS11270	COG0527	aspartate kinase activity
FGE20_RS11275	COG0083	homoserine kinase activity
FGE20_RS11280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGE20_RS11285	COG1187	pseudouridine synthase activity
FGE20_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGE20_RS11305	COG0612	Peptidase, M16
FGE20_RS11310	COG0612	Peptidase, M16
FGE20_RS11315	COG2814	Major facilitator Superfamily
FGE20_RS11325	COG2814	Major facilitator Superfamily
FGE20_RS11330	COG0778	Nitroreductase
FGE20_RS11335	COG1846	Transcriptional regulator
FGE20_RS11340	COG0724	RNA recognition motif
FGE20_RS11360	COG0805	protein transport
FGE20_RS11370	COG3119	arylsulfatase activity
FGE20_RS11375	COG1193	negative regulation of DNA recombination
FGE20_RS11380	COG0302	gtp cyclohydrolase
FGE20_RS11385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGE20_RS11395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGE20_RS11400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGE20_RS11405	COG0045	succinate-CoA ligase (ADP-forming) activity
FGE20_RS11420	COG2353	YceI-like domain
FGE20_RS11425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGE20_RS11440	COG0038	chloride channel
FGE20_RS11445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGE20_RS11450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGE20_RS11455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGE20_RS11460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGE20_RS11460	COG1321	iron dependent repressor
FGE20_RS11470	COG3263	regulation of cellular component size
FGE20_RS11480	COG0513	Belongs to the DEAD box helicase family
FGE20_RS11490	COG2194	sulfuric ester hydrolase activity
FGE20_RS11505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FGE20_RS11510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGE20_RS11520	COG2217	Heavy metal translocating P-type atpase
FGE20_RS11600	COG0415	Belongs to the DNA photolyase family
FGE20_RS11605	COG1090	epimerase
FGE20_RS11740	COG1309	transcriptional regulator
FGE20_RS11745	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FGE20_RS11780	COG0488	(ABC) transporter
FGE20_RS11875	COG1201	RNA secondary structure unwinding
FGE20_RS11900	COG0270	DNA (cytosine-5-)-methyltransferase activity
FGE20_RS12010	COG0270	DNA (cytosine-5-)-methyltransferase activity