locus-tag	class	description
FH779_RS00010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FH779_RS00020	COG1121	(ABC) transporter
FH779_RS00025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FH779_RS00030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FH779_RS00030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FH779_RS00050	COG1160	GTP binding
FH779_RS00055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FH779_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FH779_RS00085	COG3425	synthase
FH779_RS00095	COG1505	serine-type exopeptidase activity
FH779_RS00110	COG1064	alcohol dehydrogenase
FH779_RS00135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FH779_RS00150	COG0328	RNA-DNA hybrid ribonuclease activity
FH779_RS00165	COG0596	Alpha beta hydrolase
FH779_RS00170	COG0166	Belongs to the GPI family
FH779_RS00180	COG0028	Belongs to the TPP enzyme family
FH779_RS00200	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FH779_RS00205	COG0602	queuosine metabolic process
FH779_RS00210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FH779_RS00235	COG0756	dUTP diphosphatase activity
FH779_RS00240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FH779_RS00255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FH779_RS00275	COG1506	peptidase
FH779_RS00275	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS00285	COG1187	pseudouridine synthase activity
FH779_RS00290	COG1506	peptidase
FH779_RS00300	COG1187	pseudouridine synthase activity
FH779_RS00320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FH779_RS00355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FH779_RS00365	COG0470	DNA polymerase III
FH779_RS00370	COG3142	Participates in the control of copper homeostasis
FH779_RS00375	COG1446	asparaginase
FH779_RS00380	COG3537	Alpha-1,2-mannosidase
FH779_RS00395	COG2217	Heavy metal translocating P-type atpase
FH779_RS00400	COG2365	Tyrosine phosphatase family
FH779_RS00420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FH779_RS00420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FH779_RS00435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FH779_RS00445	COG2733	membrane
FH779_RS00450	COG4574	serine-type endopeptidase inhibitor activity
FH779_RS00465	COG1530	ribonuclease E activity
FH779_RS00475	COG1194	a g-specific adenine glycosylase
FH779_RS00480	COG0629	single-stranded DNA binding
FH779_RS00505	COG1703	isobutyryl-CoA mutase activity
FH779_RS00530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FH779_RS00535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FH779_RS00545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FH779_RS00565	COG2081	HI0933 family
FH779_RS00580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FH779_RS00585	COG0527	aspartate kinase activity
FH779_RS00600	COG0165	Argininosuccinate lyase
FH779_RS00605	COG1049	propionate catabolic process, 2-methylcitrate cycle
FH779_RS00610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FH779_RS00620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FH779_RS00625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FH779_RS00640	COG1253	flavin adenine dinucleotide binding
FH779_RS00665	COG0268	Binds directly to 16S ribosomal RNA
FH779_RS00675	COG0791	NLP P60 protein
FH779_RS00700	COG0436	Aminotransferase
FH779_RS00705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FH779_RS00710	COG0012	GTP binding
FH779_RS00725	COG1131	(ABC) transporter
FH779_RS00735	COG0436	Aminotransferase
FH779_RS00740	COG0287	Prephenate dehydrogenase
FH779_RS00745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FH779_RS00750	COG1162	GTPase activity
FH779_RS00760	COG1490	D-aminoacyl-tRNA deacylase activity
FH779_RS00805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FH779_RS00805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FH779_RS00810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FH779_RS00820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FH779_RS00835	COG0673	inositol 2-dehydrogenase activity
FH779_RS00840	COG1607	acyl-coa hydrolase
FH779_RS00855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FH779_RS00875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FH779_RS00875	COG0758	DNA mediated transformation
FH779_RS00885	COG1381	Involved in DNA repair and RecF pathway recombination
FH779_RS00895	COG0626	cystathionine gamma-synthase activity
FH779_RS00915	COG0596	Alpha beta hydrolase
FH779_RS00920	COG0590	tRNA wobble adenosine to inosine editing
FH779_RS00935	COG4206	TonB-dependent receptor
FH779_RS00945	COG0508	dehydrogenase complex catalyzes the overall conversion of
FH779_RS00945	COG0022	dehydrogenase e1 component
FH779_RS00955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FH779_RS00965	COG2234	aminopeptidase activity
FH779_RS00965	COG4935	Belongs to the peptidase S8 family
FH779_RS00970	COG3033	Beta-eliminating lyase
FH779_RS00975	COG1607	acyl-coa hydrolase
FH779_RS01000	COG3118	belongs to the thioredoxin family
FH779_RS01005	COG1113	amino acid transport
FH779_RS01015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FH779_RS01050	COG0133	tryptophan synthase activity
FH779_RS01055	COG0135	phosphoribosylanthranilate isomerase activity
FH779_RS01060	COG0134	indole-3-glycerol-phosphate synthase activity
FH779_RS01065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FH779_RS01070	COG0512	Glutamine amidotransferase of anthranilate synthase
FH779_RS01075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FH779_RS01080	COG1024	Enoyl-CoA hydratase
FH779_RS01090	COG4221	oxidoreductase activity
FH779_RS01100	COG0463	Glycosyl transferase, family 2
FH779_RS01135	COG3620	sequence-specific DNA binding
FH779_RS01135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FH779_RS01135	COG0617	tRNA 3'-terminal CCA addition
FH779_RS01150	COG1522	sequence-specific DNA binding
FH779_RS01155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FH779_RS01190	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FH779_RS01190	COG0662	Cupin 2, conserved barrel domain protein
FH779_RS01200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FH779_RS01205	COG1127	ABC transporter
FH779_RS01220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FH779_RS01235	COG0105	UTP biosynthetic process
FH779_RS01255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FH779_RS01260	COG0739	heme binding
FH779_RS01260	COG1196	nuclear chromosome segregation
FH779_RS01260	COG0741	lytic transglycosylase activity
FH779_RS01275	COG0431	NADPH-dependent FMN reductase
FH779_RS01285	COG3118	belongs to the thioredoxin family
FH779_RS01350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FH779_RS01370	COG1611	Belongs to the LOG family
FH779_RS01380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FH779_RS01390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FH779_RS01395	COG1629	transport
FH779_RS01395	COG4206	TonB-dependent receptor
FH779_RS01400	COG1609	Transcriptional regulator
FH779_RS01405	COG2190	(PTS) system
FH779_RS01405	COG2211	Major facilitator Superfamily
FH779_RS01410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FH779_RS01415	COG1554	hydrolase, family 65, central catalytic
FH779_RS01420	COG0366	Alpha amylase catalytic
FH779_RS01430	COG1082	Xylose isomerase domain protein TIM barrel
FH779_RS01435	COG0366	Alpha amylase catalytic
FH779_RS01460	COG0612	Peptidase, M16
FH779_RS01465	COG0022	dehydrogenase e1 component
FH779_RS01510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FH779_RS01515	COG3047	cAMP biosynthetic process
FH779_RS01520	COG1960	acyl-CoA dehydrogenase activity
FH779_RS01525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FH779_RS01530	COG4974	Belongs to the 'phage' integrase family
FH779_RS01555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FH779_RS01575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FH779_RS01580	COG0081	regulation of translation
FH779_RS01585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FH779_RS01590	COG0222	ribosome binding
FH779_RS01595	COG0085	RNA polymerase activity
FH779_RS01600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FH779_RS01610	COG0508	dehydrogenase complex catalyzes the overall conversion of
FH779_RS01655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FH779_RS01665	COG0277	FAD linked oxidase domain protein
FH779_RS01685	COG1335	isochorismatase
FH779_RS01700	COG0463	Glycosyl transferase, family 2
FH779_RS01710	COG0564	pseudouridine synthase activity
FH779_RS01720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FH779_RS01790	COG1216	Glycosyl transferase, family 2
FH779_RS01790	COG0463	Glycosyl transferase, family 2
FH779_RS01795	COG1215	transferase activity, transferring glycosyl groups
FH779_RS01800	COG0463	Glycosyl transferase, family 2
FH779_RS01805	COG1442	glycosyl transferase family 8
FH779_RS01805	COG1216	Glycosyl transferase, family 2
FH779_RS01820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FH779_RS01845	COG1216	Glycosyl transferase, family 2
FH779_RS01850	COG0562	UDP-galactopyranose mutase
FH779_RS01855	COG0463	Glycosyl transferase, family 2
FH779_RS01875	COG0237	dephospho-CoA kinase activity
FH779_RS01880	COG1862	Preprotein translocase
FH779_RS01890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FH779_RS01895	COG1132	(ABC) transporter
FH779_RS01910	COG0045	succinate-CoA ligase (ADP-forming) activity
FH779_RS01915	COG1136	(ABC) transporter
FH779_RS01940	COG1215	transferase activity, transferring glycosyl groups
FH779_RS01965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FH779_RS01965	COG0546	phosphoglycolate phosphatase activity
FH779_RS01970	COG0277	FAD linked oxidase domain protein
FH779_RS01990	COG0438	transferase activity, transferring glycosyl groups
FH779_RS01995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FH779_RS02000	COG0438	transferase activity, transferring glycosyl groups
FH779_RS02005	COG1442	glycosyl transferase family 8
FH779_RS02005	COG1216	Glycosyl transferase, family 2
FH779_RS02015	COG1215	transferase activity, transferring glycosyl groups
FH779_RS02020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FH779_RS02030	COG0489	protein tyrosine kinase activity
FH779_RS02035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FH779_RS02040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FH779_RS02045	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FH779_RS02055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FH779_RS02060	COG2261	transglycosylase associated protein
FH779_RS02065	COG1584	GPR1 FUN34 yaaH family protein
FH779_RS02070	COG0706	membrane insertase activity
FH779_RS02075	COG0504	CTP synthase activity
FH779_RS02105	COG0463	Glycosyl transferase, family 2
FH779_RS02115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FH779_RS02120	COG0306	phosphate transporter
FH779_RS02125	COG0306	phosphate transporter
FH779_RS02140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FH779_RS02145	COG0049	tRNA binding
FH779_RS02150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FH779_RS02155	COG0051	transcription antitermination factor activity, RNA binding
FH779_RS02170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FH779_RS02175	COG0088	Forms part of the polypeptide exit tunnel
FH779_RS02180	COG0089	rRNA binding
FH779_RS02185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FH779_RS02190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FH779_RS02195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FH779_RS02200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FH779_RS02205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FH779_RS02210	COG0255	Belongs to the universal ribosomal protein uL29 family
FH779_RS02215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FH779_RS02220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FH779_RS02225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FH779_RS02230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FH779_RS02235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FH779_RS02245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FH779_RS02250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FH779_RS02255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FH779_RS02260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FH779_RS02265	COG1841	ribosomal large subunit assembly
FH779_RS02270	COG0200	Binds to the 23S rRNA
FH779_RS02280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FH779_RS02285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FH779_RS02290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FH779_RS02295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FH779_RS02300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FH779_RS02305	COG0202	RNA polymerase activity
FH779_RS02310	COG0203	ribosomal protein L17
FH779_RS02315	COG4774	siderophore transport
FH779_RS02350	COG0280	phosphate acetyltransferase
FH779_RS02350	COG0281	malic enzyme
FH779_RS02365	COG0443	Heat shock 70 kDa protein
FH779_RS02370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FH779_RS02380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FH779_RS02385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FH779_RS02390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FH779_RS02400	COG0552	protein localization to endoplasmic reticulum
FH779_RS02425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FH779_RS02450	COG1702	phosphate starvation-inducible protein PhoH
FH779_RS02465	COG0606	chelatase, subunit chli
FH779_RS02545	COG1595	DNA-templated transcription, initiation
FH779_RS02560	COG2264	protein methyltransferase activity
FH779_RS02585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FH779_RS02600	COG0601	transmembrane transport
FH779_RS02605	COG0149	triose-phosphate isomerase activity
FH779_RS02650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FH779_RS02660	COG1438	arginine binding
FH779_RS02665	COG0137	argininosuccinate synthase activity
FH779_RS02670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FH779_RS02680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FH779_RS02685	COG0505	Belongs to the CarA family
FH779_RS02710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FH779_RS02715	COG0084	hydrolase, TatD family'
FH779_RS02720	COG0477	Major facilitator Superfamily
FH779_RS02725	COG0252	asparaginase activity
FH779_RS02735	COG1652	LysM domain
FH779_RS02740	COG1360	Flagellar Motor Protein
FH779_RS02755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FH779_RS02770	COG0592	DNA-directed DNA polymerase activity
FH779_RS02780	COG0288	reversible hydration of carbon dioxide
FH779_RS02790	COG4221	oxidoreductase activity
FH779_RS02820	COG5002	protein histidine kinase activity
FH779_RS02830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FH779_RS02845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FH779_RS02855	COG0783	Belongs to the Dps family
FH779_RS02865	COG3158	transport of potassium into the cell
FH779_RS02875	COG1250	3-hydroxyacyl-CoA dehydrogenase
FH779_RS02875	COG1024	Enoyl-CoA hydratase
FH779_RS02885	COG0183	Belongs to the thiolase family
FH779_RS02890	COG1960	acyl-CoA dehydrogenase activity
FH779_RS02895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FH779_RS02900	COG2234	aminopeptidase activity
FH779_RS02915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FH779_RS02935	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FH779_RS02985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FH779_RS02995	COG0148	phosphopyruvate hydratase activity
FH779_RS03015	COG2234	aminopeptidase activity
FH779_RS03045	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FH779_RS03045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FH779_RS03050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FH779_RS03050	COG0140	phosphoribosyl-ATP diphosphatase activity
FH779_RS03055	COG0501	Belongs to the peptidase M48B family
FH779_RS03070	COG3011	Protein conserved in bacteria
FH779_RS03080	COG3779	Protein conserved in bacteria
FH779_RS03090	COG2183	response to ionizing radiation
FH779_RS03100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FH779_RS03100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FH779_RS03115	COG1757	Na H antiporter
FH779_RS03120	COG0482	sulfurtransferase activity
FH779_RS03150	COG0101	tRNA pseudouridine synthase activity
FH779_RS03155	COG1132	(ABC) transporter
FH779_RS03170	COG0387	Pfam Sodium calcium exchanger
FH779_RS03195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FH779_RS03200	COG0531	amino acid
FH779_RS03205	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FH779_RS03210	COG0582	viral genome integration into host DNA
FH779_RS03245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FH779_RS03250	COG0569	domain protein
FH779_RS03290	COG2855	membrane
FH779_RS03295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FH779_RS03295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FH779_RS03305	COG3118	belongs to the thioredoxin family
FH779_RS03320	COG1858	cytochrome C peroxidase
FH779_RS03340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FH779_RS03355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FH779_RS03365	COG1090	epimerase
FH779_RS03370	COG1733	regulation of RNA biosynthetic process
FH779_RS03410	COG3621	Patatin-like phospholipase
FH779_RS03415	COG1876	peptidase activity
FH779_RS03500	COG2267	carboxylic ester hydrolase activity
FH779_RS03510	COG1528	Iron-storage protein
FH779_RS03555	COG1858	cytochrome C peroxidase
FH779_RS03575	COG0346	lactoylglutathione lyase activity
FH779_RS03625	COG1401	restriction endodeoxyribonuclease activity
FH779_RS03675	COG2207	Transcriptional regulator
FH779_RS03680	COG3621	Patatin-like phospholipase
FH779_RS03705	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FH779_RS03820	COG0437	4 iron, 4 sulfur cluster binding
FH779_RS03835	COG2010	Cytochrome c
FH779_RS03855	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FH779_RS03860	COG0358	DNA primase activity
FH779_RS03870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FH779_RS03875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FH779_RS03880	COG0697	spore germination
FH779_RS03885	COG1522	sequence-specific DNA binding
FH779_RS03905	COG2807	transmembrane transport
FH779_RS03915	COG4774	siderophore transport
FH779_RS03930	COG3720	iron ion transport
FH779_RS03940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FH779_RS03975	COG2132	Multicopper oxidase
FH779_RS03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FH779_RS04000	COG1120	ATPase activity
FH779_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS04010	COG0745	RESPONSE REGULATOR receiver
FH779_RS04015	COG2205	protein histidine kinase activity
FH779_RS04020	COG1285	pathogenesis
FH779_RS04040	COG0534	Mate efflux family protein
FH779_RS04050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FH779_RS04055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FH779_RS04070	COG0156	8-amino-7-oxononanoate synthase activity
FH779_RS04075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FH779_RS04080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FH779_RS04090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FH779_RS04100	COG0251	oxidation-reduction process
FH779_RS04105	COG1846	Transcriptional regulator
FH779_RS04130	COG4948	Mandelate Racemase Muconate Lactonizing
FH779_RS04160	COG0754	glutathionylspermidine amidase activity
FH779_RS04175	COG0427	acetyl-CoA hydrolase
FH779_RS04190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FH779_RS04195	COG1968	undecaprenyl-diphosphatase activity
FH779_RS04205	COG2177	Part of the ABC transporter FtsEX involved in
FH779_RS04210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FH779_RS04215	COG2239	Acts as a magnesium transporter
FH779_RS04225	COG3852	Histidine kinase
FH779_RS04230	COG0567	Dehydrogenase, E1 component
FH779_RS04235	COG0508	dehydrogenase complex catalyzes the overall conversion of
FH779_RS04260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FH779_RS04265	COG0747	negative chemotaxis
FH779_RS04270	COG0069	glutamate synthase activity
FH779_RS04285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FH779_RS04300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FH779_RS04300	COG0519	Catalyzes the synthesis of GMP from XMP
FH779_RS04305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FH779_RS04335	COG0791	NLP P60 protein
FH779_RS04350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FH779_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
FH779_RS04365	COG0305	Participates in initiation and elongation during chromosome replication
FH779_RS04370	COG0825	malonyl-CoA metabolic process
FH779_RS04375	COG0183	Belongs to the thiolase family
FH779_RS04405	COG0408	coproporphyrinogen oxidase activity
FH779_RS04410	COG1690	Belongs to the RtcB family
FH779_RS04420	COG3541	Predicted nucleotidyltransferase
FH779_RS04440	COG1950	PFAM Membrane protein of
FH779_RS04445	COG0423	glycine-tRNA ligase activity
FH779_RS04480	COG2356	endonuclease I
FH779_RS04490	COG0484	heat shock protein binding
FH779_RS04495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FH779_RS04505	COG0739	heme binding
FH779_RS04525	COG1418	mRNA catabolic process
FH779_RS04535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FH779_RS04560	COG1285	pathogenesis
FH779_RS04595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FH779_RS04595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FH779_RS04605	COG0730	response to heat
FH779_RS04610	COG0612	Peptidase, M16
FH779_RS04615	COG0612	Peptidase, M16
FH779_RS04620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FH779_RS04620	COG1333	cytochrome c biogenesis protein
FH779_RS04650	COG0254	rRNA binding
FH779_RS04670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FH779_RS04685	COG1136	(ABC) transporter
FH779_RS04695	COG1136	(ABC) transporter
FH779_RS04695	COG0577	efflux transmembrane transporter activity
FH779_RS04730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FH779_RS04745	COG1322	Protein conserved in bacteria
FH779_RS04755	COG1104	cysteine desulfurase activity
FH779_RS04765	COG0556	nucleotide-excision repair
FH779_RS04770	COG3956	TIGRFAM MazG family protein
FH779_RS04780	COG0242	peptide deformylase activity
FH779_RS04785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FH779_RS04790	COG2171	N-acyltransferase activity
FH779_RS04795	COG0463	Glycosyl transferase, family 2
FH779_RS04800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FH779_RS04825	COG0517	IMP dehydrogenase activity
FH779_RS04825	COG0617	tRNA 3'-terminal CCA addition
FH779_RS04825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FH779_RS04835	COG2373	Large extracellular alpha-helical protein
FH779_RS04850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FH779_RS04890	COG0180	Tryptophanyl-tRNA synthetase
FH779_RS04895	COG0316	Belongs to the HesB IscA family
FH779_RS04905	COG0719	Fe-S assembly protein
FH779_RS04910	COG0396	ATPase activity
FH779_RS04915	COG0719	Fe-S assembly protein
FH779_RS04920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FH779_RS04935	COG0629	single-stranded DNA binding
FH779_RS04950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FH779_RS04955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FH779_RS04970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FH779_RS04975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FH779_RS04980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FH779_RS05005	COG3001	Fructosamine kinase
FH779_RS05010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FH779_RS05015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FH779_RS05030	COG0860	N-Acetylmuramoyl-L-alanine amidase
FH779_RS05040	COG0714	Associated with various cellular activities
FH779_RS05065	COG3012	SEC-C Motif Domain Protein
FH779_RS05080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FH779_RS05100	COG0778	Nitroreductase
FH779_RS05110	COG0431	NADPH-dependent FMN reductase
FH779_RS05125	COG0745	RESPONSE REGULATOR receiver
FH779_RS05130	COG5002	protein histidine kinase activity
FH779_RS05195	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS05195	COG1506	peptidase
FH779_RS05205	COG4251	negative regulation of phosphorylation
FH779_RS05225	COG1428	Deoxynucleoside kinase
FH779_RS05270	COG4206	TonB-dependent receptor
FH779_RS05270	COG1629	transport
FH779_RS05295	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FH779_RS05295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FH779_RS05310	COG1960	acyl-CoA dehydrogenase activity
FH779_RS05315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FH779_RS05330	COG1595	DNA-templated transcription, initiation
FH779_RS05345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FH779_RS05350	COG1185	polyribonucleotide nucleotidyltransferase activity
FH779_RS05360	COG3591	Belongs to the peptidase S1B family
FH779_RS05365	COG1234	tRNA 3'-trailer cleavage
FH779_RS05400	COG3023	N-Acetylmuramoyl-L-alanine amidase
FH779_RS05550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FH779_RS05555	COG0210	DNA helicase
FH779_RS05590	COG2207	Transcriptional regulator
FH779_RS05610	COG0038	chloride channel
FH779_RS05630	COG0551	DNA topoisomerase type I activity
FH779_RS05630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FH779_RS05655	COG2217	Heavy metal translocating P-type atpase
FH779_RS05680	COG2814	Major facilitator Superfamily
FH779_RS05685	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FH779_RS05710	COG1902	pentaerythritol trinitrate reductase activity
FH779_RS05710	COG0446	pyridine nucleotide-disulphide oxidoreductase
FH779_RS05715	COG1053	succinate dehydrogenase
FH779_RS05730	COG2963	transposase activity
FH779_RS05735	COG2207	Transcriptional regulator
FH779_RS05780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FH779_RS05785	COG2217	Heavy metal translocating P-type atpase
FH779_RS05790	COG1914	H( )-stimulated, divalent metal cation uptake system
FH779_RS05795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FH779_RS05800	COG1764	response to oxidative stress
FH779_RS05805	COG1917	Cupin 2, conserved barrel domain protein
FH779_RS05805	COG4977	sequence-specific DNA binding
FH779_RS05810	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FH779_RS05825	COG2132	Multicopper oxidase
FH779_RS05830	COG2814	Major facilitator Superfamily
FH779_RS05880	COG1271	oxidase subunit
FH779_RS05890	COG0523	cobalamin synthesis protein
FH779_RS05895	COG1408	metallophosphoesterase
FH779_RS05905	COG1301	dicarboxylic acid transport
FH779_RS05920	COG0156	8-amino-7-oxononanoate synthase activity
FH779_RS05940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FH779_RS05945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FH779_RS05950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS05965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FH779_RS05990	COG1649	PFAM Uncharacterised BCR, COG1649
FH779_RS06000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FH779_RS06005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FH779_RS06015	COG1522	sequence-specific DNA binding
FH779_RS06030	COG1760	l-serine dehydratase
FH779_RS06035	COG0513	Belongs to the DEAD box helicase family
FH779_RS06040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FH779_RS06060	COG0436	Aminotransferase
FH779_RS06065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FH779_RS06085	COG2195	Cleaves the N-terminal amino acid of tripeptides
FH779_RS06100	COG0531	amino acid
FH779_RS06100	COG0531	amino acid
FH779_RS06105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FH779_RS06115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FH779_RS06120	COG0205	6-phosphofructokinase activity
FH779_RS06130	COG1363	Peptidase, m42
FH779_RS06140	COG1739	Uncharacterized protein family UPF0029
FH779_RS06150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FH779_RS06150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FH779_RS06160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FH779_RS06165	COG0586	Pfam SNARE associated Golgi protein
FH779_RS06170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FH779_RS06180	COG3655	Transcriptional regulator
FH779_RS06200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FH779_RS06220	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FH779_RS06240	COG0831	urea catabolic process
FH779_RS06245	COG0832	Belongs to the urease beta subunit family
FH779_RS06250	COG0804	urea catabolic process
FH779_RS06260	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FH779_RS06265	COG0830	nickel cation binding
FH779_RS06270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FH779_RS06275	COG0829	nickel cation binding
FH779_RS06340	COG2197	response regulator
FH779_RS06345	COG0542	response to heat
FH779_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS06415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FH779_RS06420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FH779_RS06435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FH779_RS06440	COG0778	Nitroreductase
FH779_RS06460	COG1278	Cold shock
FH779_RS06530	COG4771	TonB-dependent receptor
FH779_RS06595	COG3275	phosphorelay sensor kinase activity
FH779_RS06600	COG3279	Response regulator of the LytR AlgR family
FH779_RS06645	COG4895	conserved protein (DUF2196)
FH779_RS06650	COG1733	regulation of RNA biosynthetic process
FH779_RS06730	COG4771	TonB-dependent receptor
FH779_RS06780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FH779_RS06805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FH779_RS06840	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FH779_RS06845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FH779_RS06880	COG4771	TonB-dependent receptor
FH779_RS06890	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS06890	COG1506	peptidase
FH779_RS06890	COG4946	Tricorn protease homolog
FH779_RS06960	COG0415	Belongs to the DNA photolyase family
FH779_RS06965	COG3040	lipid binding
FH779_RS07000	COG2351	hydroxyisourate hydrolase activity
FH779_RS07030	COG1528	Iron-storage protein
FH779_RS07110	COG4771	TonB-dependent receptor
FH779_RS07130	COG4221	oxidoreductase activity
FH779_RS07170	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FH779_RS07200	COG0798	PFAM Bile acid sodium symporter
FH779_RS07220	COG1278	Cold shock
FH779_RS07225	COG0387	Pfam Sodium calcium exchanger
FH779_RS07240	COG0778	Nitroreductase
FH779_RS07250	COG1764	response to oxidative stress
FH779_RS07255	COG1846	Transcriptional regulator
FH779_RS07260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FH779_RS07260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FH779_RS07265	COG3059	membrane
FH779_RS07290	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS07290	COG1506	peptidase
FH779_RS07340	COG0025	NhaP-type Na H and K H
FH779_RS07355	COG3685	Protein conserved in bacteria
FH779_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS07380	COG3278	Belongs to the heme-copper respiratory oxidase family
FH779_RS07415	COG4221	oxidoreductase activity
FH779_RS07425	COG1446	asparaginase
FH779_RS07430	COG4242	Belongs to the peptidase S51 family
FH779_RS07435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FH779_RS07435	COG0189	ligase activity
FH779_RS07450	COG2267	carboxylic ester hydrolase activity
FH779_RS07460	COG1528	Iron-storage protein
FH779_RS07475	COG3550	peptidyl-serine autophosphorylation
FH779_RS07510	COG1943	Transposase
FH779_RS07515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FH779_RS07525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FH779_RS07535	COG0322	excinuclease ABC activity
FH779_RS07540	COG2135	peptidase activity
FH779_RS07560	COG4771	TonB-dependent receptor
FH779_RS07570	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS07570	COG1506	peptidase
FH779_RS07605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FH779_RS07635	COG2096	Adenosyltransferase
FH779_RS07650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FH779_RS07650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FH779_RS07655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FH779_RS07660	COG0671	phosphoesterase, PA-phosphatase related
FH779_RS07670	COG4717	serine-type aminopeptidase activity
FH779_RS07675	COG0321	lipoyl(octanoyl) transferase activity
FH779_RS07685	COG4771	TonB-dependent receptor
FH779_RS07690	COG0702	epimerase
FH779_RS07700	COG1472	Belongs to the glycosyl hydrolase 3 family
FH779_RS07720	COG2755	lipolytic protein G-D-S-L family
FH779_RS07740	COG2755	lipolytic protein G-D-S-L family
FH779_RS07750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FH779_RS07770	COG0702	epimerase
FH779_RS07775	COG4771	TonB-dependent receptor
FH779_RS07785	COG1629	transport
FH779_RS07790	COG1609	Transcriptional regulator
FH779_RS07795	COG2721	sulfolactate sulfo-lyase activity
FH779_RS07800	COG0246	Mannitol dehydrogenase
FH779_RS07805	COG2271	Major facilitator Superfamily
FH779_RS07810	COG0800	Aldolase
FH779_RS07820	COG1904	glucuronate isomerase
FH779_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS07830	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FH779_RS07855	COG1253	flavin adenine dinucleotide binding
FH779_RS07915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FH779_RS07940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FH779_RS07945	COG0569	domain protein
FH779_RS07950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FH779_RS08010	COG1393	Belongs to the ArsC family
FH779_RS08045	COG3040	lipid binding
FH779_RS08050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FH779_RS08060	COG2195	Cleaves the N-terminal amino acid of tripeptides
FH779_RS08135	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FH779_RS08140	COG0671	phosphoesterase, PA-phosphatase related
FH779_RS08150	COG0508	dehydrogenase complex catalyzes the overall conversion of
FH779_RS08155	COG0022	dehydrogenase e1 component
FH779_RS08160	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FH779_RS08165	COG1309	transcriptional regulator
FH779_RS08170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FH779_RS08175	COG3396	Phenylacetate-CoA oxygenase
FH779_RS08180	COG3460	Phenylacetate-CoA oxygenase
FH779_RS08185	COG3396	Phenylacetate-CoA oxygenase
FH779_RS08190	COG2151	metal-sulfur cluster biosynthetic enzyme
FH779_RS08195	COG1024	Enoyl-CoA hydratase
FH779_RS08200	COG1250	3-hydroxyacyl-CoA dehydrogenase
FH779_RS08210	COG0183	Belongs to the thiolase family
FH779_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
FH779_RS08220	COG2030	dehydratase
FH779_RS08245	COG0545	Peptidyl-prolyl cis-trans isomerase
FH779_RS08260	COG2855	membrane
FH779_RS08265	COG0583	DNA-binding transcription factor activity
FH779_RS08280	COG1764	response to oxidative stress
FH779_RS08310	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FH779_RS08330	COG1785	Belongs to the alkaline phosphatase family
FH779_RS08345	COG1022	Amp-dependent synthetase and ligase
FH779_RS08350	COG1022	Amp-dependent synthetase and ligase
FH779_RS08360	COG1022	Amp-dependent synthetase and ligase
FH779_RS08370	COG0513	Belongs to the DEAD box helicase family
FH779_RS08385	COG4115	mRNA cleavage
FH779_RS08390	COG0024	Methionine aminopeptidase
FH779_RS08405	COG3384	dioxygenase
FH779_RS08410	COG2353	YceI-like domain
FH779_RS08415	COG1115	amino acid carrier protein
FH779_RS08425	COG0735	belongs to the Fur family
FH779_RS08430	COG2837	iron assimilation
FH779_RS08445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FH779_RS08460	COG2814	Major facilitator Superfamily
FH779_RS08475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FH779_RS08490	COG0460	homoserine dehydrogenase
FH779_RS08500	COG4771	TonB-dependent receptor
FH779_RS08520	COG0525	valine-tRNA ligase activity
FH779_RS08545	COG1959	2 iron, 2 sulfur cluster binding
FH779_RS08550	COG0037	tRNA processing
FH779_RS08580	COG2910	NAD(P)H-binding
FH779_RS08600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FH779_RS08620	COG2318	DinB family
FH779_RS08665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS08675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FH779_RS08685	COG0753	catalase activity
FH779_RS08695	COG1914	H( )-stimulated, divalent metal cation uptake system
FH779_RS08705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FH779_RS08720	COG0402	S-adenosylhomocysteine deaminase activity
FH779_RS08725	COG1834	amidinotransferase
FH779_RS08755	COG2259	Doxx family
FH779_RS08765	COG2267	carboxylic ester hydrolase activity
FH779_RS08775	COG0336	Belongs to the RNA methyltransferase TrmD family
FH779_RS08780	COG0113	porphobilinogen synthase activity
FH779_RS08790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FH779_RS08795	COG0494	nUDIX hydrolase
FH779_RS08815	COG1858	cytochrome C peroxidase
FH779_RS08830	COG0577	efflux transmembrane transporter activity
FH779_RS08840	COG1136	(ABC) transporter
FH779_RS08840	COG0577	efflux transmembrane transporter activity
FH779_RS08850	COG2204	response regulator
FH779_RS08860	COG2217	Heavy metal translocating P-type atpase
FH779_RS08920	COG2897	thiosulfate sulfurtransferase activity
FH779_RS08940	COG1183	phosphatidylcholine synthase activity
FH779_RS08950	COG0179	Fumarylacetoacetate (FAA) hydrolase
FH779_RS08965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FH779_RS08975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FH779_RS08980	COG1528	Iron-storage protein
FH779_RS09005	COG0497	DNA recombination
FH779_RS09010	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FH779_RS09015	COG0023	Translation Initiation Factor
FH779_RS09035	COG3339	Conserved Protein
FH779_RS09045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FH779_RS09050	COG2176	DNA-directed DNA polymerase activity
FH779_RS09065	COG2076	Multidrug Resistance protein
FH779_RS09075	COG0175	sulfate reduction
FH779_RS09090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FH779_RS09110	COG0346	lactoylglutathione lyase activity
FH779_RS09130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FH779_RS09170	COG0656	L-ascorbic acid biosynthetic process
FH779_RS09190	COG0702	epimerase
FH779_RS09195	COG4206	TonB-dependent receptor
FH779_RS09195	COG1629	transport
FH779_RS09205	COG3275	phosphorelay sensor kinase activity
FH779_RS09225	COG1215	transferase activity, transferring glycosyl groups
FH779_RS09240	COG0564	pseudouridine synthase activity
FH779_RS09250	COG1538	Outer membrane efflux protein
FH779_RS09280	COG0484	heat shock protein binding
FH779_RS09295	COG1166	arginine decarboxylase activity
FH779_RS09300	COG1192	Involved in chromosome partitioning
FH779_RS09305	COG1475	DNA binding
FH779_RS09315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FH779_RS09355	COG3340	Belongs to the peptidase S51 family
FH779_RS09370	COG4152	abc transporter atp-binding protein
FH779_RS09385	COG1278	Cold shock
FH779_RS09390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FH779_RS09400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FH779_RS09405	COG0501	Belongs to the peptidase M48B family
FH779_RS09420	COG0259	pyridoxamine-phosphate oxidase activity
FH779_RS09425	COG1678	Uncharacterized ACR, COG1678
FH779_RS09455	COG3279	Response regulator of the LytR AlgR family
FH779_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
FH779_RS09500	COG0659	secondary active sulfate transmembrane transporter activity
FH779_RS09505	COG4771	TonB-dependent receptor
FH779_RS09560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FH779_RS09610	COG2207	Transcriptional regulator
FH779_RS09610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FH779_RS09635	COG0095	Lipoate-protein ligase
FH779_RS09640	COG4206	TonB-dependent receptor
FH779_RS09690	COG2217	Heavy metal translocating P-type atpase
FH779_RS09730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FH779_RS09755	COG4771	TonB-dependent receptor
FH779_RS09770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FH779_RS09790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FH779_RS09880	COG2972	Histidine kinase
FH779_RS09905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FH779_RS09915	COG3537	Alpha-1,2-mannosidase
FH779_RS09920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FH779_RS09935	COG0116	Belongs to the methyltransferase superfamily
FH779_RS09955	COG2226	methyltransferase
FH779_RS10010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FH779_RS10020	COG0861	Integral membrane protein TerC family
FH779_RS10025	COG0561	phosphatase activity
FH779_RS10040	COG1741	Belongs to the pirin family
FH779_RS10055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FH779_RS10060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FH779_RS10070	COG2356	endonuclease I
FH779_RS10075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FH779_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS10110	COG0514	ATP-dependent DNA helicase (RecQ)
FH779_RS10115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FH779_RS10125	COG0477	Major facilitator Superfamily
FH779_RS10140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FH779_RS10145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FH779_RS10165	COG1114	Component of the transport system for branched-chain amino acids
FH779_RS10180	COG4452	Inner membrane protein CreD
FH779_RS10195	COG0300	oxidoreductase activity
FH779_RS10205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FH779_RS10210	COG2814	Major facilitator Superfamily
FH779_RS10215	COG0667	Aldo Keto reductase
FH779_RS10220	COG2972	Histidine kinase
FH779_RS10230	COG2814	Major facilitator Superfamily
FH779_RS10235	COG0346	lactoylglutathione lyase activity
FH779_RS10240	COG1902	pentaerythritol trinitrate reductase activity
FH779_RS10245	COG1252	NADH dehydrogenase
FH779_RS10265	COG0519	Catalyzes the synthesis of GMP from XMP
FH779_RS10280	COG0673	inositol 2-dehydrogenase activity
FH779_RS10305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FH779_RS10315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FH779_RS10345	COG2890	protein-(glutamine-N5) methyltransferase activity
FH779_RS10370	COG1703	isobutyryl-CoA mutase activity
FH779_RS10370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FH779_RS10370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FH779_RS10380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FH779_RS10385	COG1611	Belongs to the LOG family
FH779_RS10390	COG1193	negative regulation of DNA recombination
FH779_RS10405	COG0450	alkyl hydroperoxide reductase
FH779_RS10410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS10435	COG0561	phosphatase activity
FH779_RS10445	COG1012	belongs to the aldehyde dehydrogenase family
FH779_RS10450	COG1960	acyl-CoA dehydrogenase activity
FH779_RS10465	COG1228	amidohydrolase
FH779_RS10470	COG2354	Protein conserved in bacteria
FH779_RS10480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FH779_RS10485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FH779_RS10500	COG2270	Major facilitator Superfamily
FH779_RS10525	COG0017	Asparaginyl-tRNA synthetase
FH779_RS10540	COG0233	cytoplasmic translational termination
FH779_RS10545	COG0528	UMP kinase activity
FH779_RS10550	COG0084	hydrolase, TatD family'
FH779_RS10570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FH779_RS10580	COG0038	chloride channel
FH779_RS10630	COG0018	arginyl-trna synthetase
FH779_RS10635	COG0513	Belongs to the DEAD box helicase family
FH779_RS10645	COG1522	sequence-specific DNA binding
FH779_RS10650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FH779_RS10670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FH779_RS10675	COG2949	membrane
FH779_RS10685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FH779_RS10690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FH779_RS10695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FH779_RS10695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FH779_RS10700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FH779_RS10705	COG1078	dGTPase activity
FH779_RS10710	COG2204	response regulator
FH779_RS10715	COG0802	atpase or kinase
FH779_RS10720	COG0686	Belongs to the AlaDH PNT family
FH779_RS10755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FH779_RS10760	COG1663	tetraacyldisaccharide 4'-kinase activity
FH779_RS10790	COG1022	Amp-dependent synthetase and ligase
FH779_RS10820	COG1946	Acyl-CoA thioesterase
FH779_RS10900	COG3022	response to hydroperoxide
FH779_RS10905	COG0009	L-threonylcarbamoyladenylate synthase
FH779_RS10935	COG0326	Molecular chaperone. Has ATPase activity
FH779_RS10940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FH779_RS10945	COG1053	succinate dehydrogenase
FH779_RS10955	COG1595	DNA-templated transcription, initiation
FH779_RS11000	COG0572	uridine kinase
FH779_RS11010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FH779_RS11020	COG1289	transmembrane transporter activity
FH779_RS11025	COG1132	(ABC) transporter
FH779_RS11040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FH779_RS11050	COG0488	(ABC) transporter
FH779_RS11065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FH779_RS11070	COG2224	Isocitrate lyase
FH779_RS11095	COG4977	sequence-specific DNA binding
FH779_RS11100	COG4716	Myosin-crossreactive antigen
FH779_RS11130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FH779_RS11155	COG0679	Auxin Efflux Carrier
FH779_RS11170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FH779_RS11180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FH779_RS11190	COG0004	ammonium transporteR
FH779_RS11200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FH779_RS11200	COG0392	lysyltransferase activity
FH779_RS11270	COG0492	ferredoxin-NADP+ reductase activity
FH779_RS11290	COG4651	solute:proton antiporter activity
FH779_RS11290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FH779_RS11295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FH779_RS11310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FH779_RS11325	COG0628	permease
FH779_RS11330	COG1446	asparaginase
FH779_RS11345	COG0427	acetyl-CoA hydrolase
FH779_RS11350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FH779_RS11355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FH779_RS11360	COG0386	Belongs to the glutathione peroxidase family
FH779_RS11365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FH779_RS11415	COG0653	protein targeting
FH779_RS11430	COG5297	Belongs to the glycosyl hydrolase family 6
FH779_RS11435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FH779_RS11445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS11460	COG2824	Alkylphosphonate utilization operon protein PhnA
FH779_RS11480	COG0488	(ABC) transporter
FH779_RS11490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FH779_RS11495	COG1575	Belongs to the MenA family. Type 1 subfamily
FH779_RS11525	COG2755	lipolytic protein G-D-S-L family
FH779_RS11540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FH779_RS11550	COG1169	isochorismate synthase
FH779_RS11555	COG2050	protein possibly involved in aromatic compounds catabolism
FH779_RS11570	COG1695	Transcriptional regulator
FH779_RS11585	COG0071	Belongs to the small heat shock protein (HSP20) family
FH779_RS11610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FH779_RS11620	COG1215	transferase activity, transferring glycosyl groups
FH779_RS11630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FH779_RS11655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FH779_RS11685	COG1131	(ABC) transporter
FH779_RS11705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FH779_RS11725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FH779_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
FH779_RS11745	COG2986	histidine ammonia-lyase
FH779_RS11750	COG0644	oxidoreductase
FH779_RS11760	COG0335	large ribosomal subunit rRNA binding
FH779_RS11775	COG2326	polyphosphate kinase activity
FH779_RS11790	COG1999	signal sequence binding
FH779_RS11795	COG2249	NAD(P)H dehydrogenase (quinone) activity
FH779_RS11805	COG0583	DNA-binding transcription factor activity
FH779_RS11815	COG4585	Histidine kinase
FH779_RS11830	COG0730	response to heat
FH779_RS11845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FH779_RS11860	COG0175	sulfate reduction
FH779_RS11865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FH779_RS11890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FH779_RS11905	COG0438	transferase activity, transferring glycosyl groups
FH779_RS11910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FH779_RS11915	COG1472	Belongs to the glycosyl hydrolase 3 family
FH779_RS11935	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FH779_RS11950	COG1397	ADP-ribosylglycohydrolase
FH779_RS11955	COG4628	conserved protein (DUF2132)
FH779_RS11965	COG0151	Belongs to the GarS family
FH779_RS11980	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FH779_RS11985	COG1047	Peptidyl-prolyl cis-trans
FH779_RS11990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FH779_RS11995	COG4260	virion core protein, lumpy skin disease virus
FH779_RS12030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FH779_RS12035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FH779_RS12045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FH779_RS12045	COG0047	phosphoribosylformylglycinamidine synthase activity
FH779_RS12055	COG1368	sulfuric ester hydrolase activity
FH779_RS12060	COG1597	lipid kinase activity
FH779_RS12065	COG0745	RESPONSE REGULATOR receiver
FH779_RS12070	COG5002	protein histidine kinase activity
FH779_RS12080	COG0488	(ABC) transporter
FH779_RS12085	COG2204	response regulator
FH779_RS12100	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FH779_RS12110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FH779_RS12120	COG2205	protein histidine kinase activity
FH779_RS12125	COG5002	protein histidine kinase activity
FH779_RS12195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FH779_RS12220	COG4895	conserved protein (DUF2196)
FH779_RS12250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FH779_RS12250	COG3153	acetyltransferase
FH779_RS12280	COG0217	transcriptional regulatory protein
FH779_RS12285	COG0339	signal peptide processing
FH779_RS12300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FH779_RS12310	COG2076	Multidrug Resistance protein
FH779_RS12320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FH779_RS12385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FH779_RS12390	COG1295	ribonuclease BN
FH779_RS12395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FH779_RS12405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FH779_RS12410	COG1234	tRNA 3'-trailer cleavage
FH779_RS12415	COG0419	ATPase involved in DNA repair
FH779_RS12420	COG0420	3'-5' exonuclease activity
FH779_RS12455	COG1137	ATPase activity
FH779_RS12470	COG3876	Protein conserved in bacteria
FH779_RS12535	COG3275	phosphorelay sensor kinase activity
FH779_RS12575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FH779_RS12590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FH779_RS12600	COG0006	proline dipeptidase activity
FH779_RS12605	COG0360	Binds together with S18 to 16S ribosomal RNA
FH779_RS12610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FH779_RS12615	COG0359	binds to the 23S rRNA
FH779_RS12625	COG2972	Histidine kinase
FH779_RS12630	COG3279	Response regulator of the LytR AlgR family
FH779_RS12635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FH779_RS12650	COG2226	methyltransferase
FH779_RS12660	COG1960	acyl-CoA dehydrogenase activity
FH779_RS12665	COG0179	Fumarylacetoacetate (FAA) hydrolase
FH779_RS12670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FH779_RS12675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FH779_RS12680	COG0052	Belongs to the universal ribosomal protein uS2 family
FH779_RS12685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FH779_RS12695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FH779_RS12710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FH779_RS12725	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FH779_RS12730	COG1917	Cupin 2, conserved barrel domain protein
FH779_RS12730	COG2207	Transcriptional regulator
FH779_RS12760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FH779_RS12770	COG2255	four-way junction helicase activity
FH779_RS12775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FH779_RS12810	COG0194	GDP metabolic process
FH779_RS12820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FH779_RS12825	COG0791	NLP P60 protein
FH779_RS12845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FH779_RS12860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FH779_RS12875	COG1704	LemA family
FH779_RS12885	COG0247	lactate metabolic process
FH779_RS12885	COG2181	nitrate reductase activity
FH779_RS12895	COG0247	lactate metabolic process
FH779_RS12895	COG2181	nitrate reductase activity
FH779_RS12905	COG1388	LysM domain
FH779_RS12905	COG0860	N-Acetylmuramoyl-L-alanine amidase
FH779_RS12915	COG0251	oxidation-reduction process
FH779_RS12925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FH779_RS12935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FH779_RS12940	COG0511	ligase activity, forming carbon-carbon bonds
FH779_RS12945	COG0439	Biotin carboxylase
FH779_RS12950	COG0544	peptidyl-prolyl cis-trans isomerase activity
FH779_RS12960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FH779_RS12975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS12980	COG0772	Belongs to the SEDS family
FH779_RS13000	COG1077	Cell shape determining protein MreB Mrl
FH779_RS13005	COG0616	signal peptide processing
FH779_RS13010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FH779_RS13010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FH779_RS13020	COG0322	excinuclease ABC activity
FH779_RS13025	COG0433	COG0433 Predicted ATPase
FH779_RS13040	COG0705	Rhomboid family
FH779_RS13045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FH779_RS13050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FH779_RS13055	COG1331	Highly conserved protein containing a thioredoxin domain
FH779_RS13060	COG0519	Catalyzes the synthesis of GMP from XMP
FH779_RS13065	COG0697	spore germination
FH779_RS13080	COG2153	protein acetylation
FH779_RS13085	COG0300	oxidoreductase activity
FH779_RS13130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FH779_RS13140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FH779_RS13175	COG0516	GMP reductase activity
FH779_RS13175	COG0517	IMP dehydrogenase activity
FH779_RS13190	COG4771	TonB-dependent receptor
FH779_RS13195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FH779_RS13205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FH779_RS13210	COG1181	Belongs to the D-alanine--D-alanine ligase family
FH779_RS13215	COG0515	serine threonine protein kinase
FH779_RS13215	COG2815	serine threonine protein kinase
FH779_RS13220	COG0564	pseudouridine synthase activity
FH779_RS13225	COG0513	Belongs to the DEAD box helicase family
FH779_RS13245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FH779_RS13260	COG0322	excinuclease ABC activity
FH779_RS13265	COG1074	ATP-dependent DNA helicase activity
FH779_RS13300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FH779_RS13320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FH779_RS13335	COG1546	Belongs to the CinA family
FH779_RS13335	COG1058	Belongs to the CinA family
FH779_RS13350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FH779_RS13360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FH779_RS13365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FH779_RS13365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FH779_RS13370	COG0799	negative regulation of ribosome biogenesis
FH779_RS13375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FH779_RS13385	COG4589	Belongs to the CDS family
FH779_RS13390	COG0688	phosphatidylethanolamine metabolic process
FH779_RS13405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FH779_RS13410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FH779_RS13415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FH779_RS13425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FH779_RS13440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FH779_RS13455	COG0542	response to heat
FH779_RS13490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FH779_RS13495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FH779_RS13505	COG0167	dihydroorotate dehydrogenase activity
FH779_RS13520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FH779_RS13525	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FH779_RS13550	COG2884	Cell division ATP-binding protein ftsE
FH779_RS13555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FH779_RS13560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FH779_RS13570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FH779_RS13580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FH779_RS13595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FH779_RS13600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FH779_RS13615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FH779_RS13645	COG1215	transferase activity, transferring glycosyl groups
FH779_RS13655	COG0745	RESPONSE REGULATOR receiver
FH779_RS13660	COG3850	Histidine kinase
FH779_RS13660	COG3437	response regulator, receiver
FH779_RS13660	COG2205	protein histidine kinase activity
FH779_RS13660	COG4999	Histidine kinase
FH779_RS13670	COG4999	Histidine kinase
FH779_RS13670	COG3850	Histidine kinase
FH779_RS13670	COG3437	response regulator, receiver
FH779_RS13670	COG2205	protein histidine kinase activity
FH779_RS13680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FH779_RS13685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FH779_RS13745	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FH779_RS13755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FH779_RS13760	COG0612	Peptidase, M16
FH779_RS13815	COG0135	phosphoribosylanthranilate isomerase activity
FH779_RS13820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FH779_RS13865	COG0488	(ABC) transporter
FH779_RS13910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FH779_RS13930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FH779_RS13935	COG2204	response regulator
FH779_RS13965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FH779_RS13970	COG0459	protein refolding
FH779_RS13980	COG0066	3-isopropylmalate dehydratase activity
FH779_RS13985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FH779_RS13990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FH779_RS14000	COG0579	oxidoreductase
FH779_RS14005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FH779_RS14010	COG1610	YqeY-like protein
FH779_RS14015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FH779_RS14030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FH779_RS14035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FH779_RS14040	COG0772	Belongs to the SEDS family
FH779_RS14045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FH779_RS14050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FH779_RS14055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FH779_RS14070	COG0275	rRNA processing
FH779_RS14075	COG2001	Belongs to the MraZ family
FH779_RS14085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FH779_RS14095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FH779_RS14100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FH779_RS14115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FH779_RS14120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FH779_RS14175	COG4974	Belongs to the 'phage' integrase family
FH779_RS14195	COG4115	mRNA cleavage
FH779_RS14210	COG4974	Belongs to the 'phage' integrase family
FH779_RS14230	COG4115	mRNA cleavage
FH779_RS14250	COG0442	prolyl-tRNA aminoacylation
FH779_RS14270	COG0708	Exodeoxyribonuclease III
FH779_RS14295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FH779_RS14305	COG4974	Belongs to the 'phage' integrase family
FH779_RS14310	COG0793	Belongs to the peptidase S41A family
FH779_RS14315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FH779_RS14315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FH779_RS14335	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FH779_RS14345	COG0742	ribosomal rna small subunit methyltransferase
FH779_RS14360	COG0545	Peptidyl-prolyl cis-trans isomerase
FH779_RS14370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FH779_RS14375	COG4977	sequence-specific DNA binding
FH779_RS14375	COG1917	Cupin 2, conserved barrel domain protein
FH779_RS14385	COG0402	S-adenosylhomocysteine deaminase activity
FH779_RS14390	COG0666	response to abiotic stimulus
FH779_RS14395	COG0402	S-adenosylhomocysteine deaminase activity
FH779_RS14405	COG1674	ftsk spoiiie
FH779_RS14415	COG0795	lipopolysaccharide-transporting ATPase activity
FH779_RS14420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FH779_RS14420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FH779_RS14430	COG0697	spore germination
FH779_RS14440	COG0539	negative regulation of cytoplasmic translation
FH779_RS14440	COG2183	response to ionizing radiation
FH779_RS14455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FH779_RS14460	COG0488	(ABC) transporter
FH779_RS14475	COG0475	glutathione-regulated potassium exporter activity
FH779_RS14485	COG0187	DNA topoisomerase II activity
FH779_RS14490	COG0357	Ribosomal RNA small subunit methyltransferase G
FH779_RS14515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FH779_RS14535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FH779_RS14540	COG2211	Major facilitator Superfamily
FH779_RS14550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FH779_RS14560	COG0805	protein transport
FH779_RS14565	COG0517	IMP dehydrogenase activity
FH779_RS14565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FH779_RS14570	COG0514	ATP-dependent DNA helicase (RecQ)
FH779_RS14575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FH779_RS14590	COG2226	methyltransferase
FH779_RS14610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FH779_RS14610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FH779_RS14615	COG0633	Ferredoxin
FH779_RS14630	COG0492	ferredoxin-NADP+ reductase activity
FH779_RS14635	COG1733	regulation of RNA biosynthetic process
FH779_RS14650	COG0436	Aminotransferase
FH779_RS14655	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FH779_RS14660	COG1250	3-hydroxyacyl-CoA dehydrogenase
FH779_RS14670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FH779_RS14680	COG5002	protein histidine kinase activity
FH779_RS14685	COG0745	RESPONSE REGULATOR receiver
FH779_RS14715	COG0513	Belongs to the DEAD box helicase family
FH779_RS14745	COG1842	Phage shock protein A
FH779_RS14765	COG2255	four-way junction helicase activity
FH779_RS14775	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FH779_RS14810	COG0481	GTPase activity
FH779_RS14825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FH779_RS14855	COG2137	regulation of response to DNA damage stimulus
FH779_RS14865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FH779_RS14880	COG2239	Acts as a magnesium transporter
FH779_RS14885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FH779_RS14955	COG0285	dihydrofolate synthase activity
FH779_RS14960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FH779_RS14970	COG2267	carboxylic ester hydrolase activity
FH779_RS14975	COG2267	carboxylic ester hydrolase activity
FH779_RS14980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FH779_RS14985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FH779_RS14990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FH779_RS14995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FH779_RS15000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FH779_RS15005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FH779_RS15010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FH779_RS15015	COG0356	it plays a direct role in the translocation of protons across the membrane
FH779_RS15060	COG4771	TonB-dependent receptor
FH779_RS15065	COG0215	cysteine-tRNA ligase activity
FH779_RS15070	COG0302	gtp cyclohydrolase
FH779_RS15075	COG2986	histidine ammonia-lyase
FH779_RS15090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FH779_RS15100	COG2388	GCN5-related N-acetyl-transferase
FH779_RS15110	COG0405	Gamma-glutamyltransferase
FH779_RS15120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FH779_RS15125	COG2251	uridine kinase activity
FH779_RS15125	COG0195	Participates in both transcription termination and antitermination
FH779_RS15130	COG0779	Required for maturation of 30S ribosomal subunits
FH779_RS15140	COG0668	transmembrane transport
FH779_RS15145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FH779_RS15150	COG0596	Alpha beta hydrolase
FH779_RS15185	COG1214	PFAM Peptidase M22, glycoprotease
FH779_RS15190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FH779_RS15210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FH779_RS15225	COG0509	glycine decarboxylation via glycine cleavage system
FH779_RS15235	COG0632	four-way junction helicase activity
FH779_RS15245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FH779_RS15250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FH779_RS15255	COG2169	Transcriptional regulator
FH779_RS15270	COG0348	domain, Protein
FH779_RS15295	COG2217	Heavy metal translocating P-type atpase
FH779_RS15310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FH779_RS15320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FH779_RS15325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FH779_RS15330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FH779_RS15335	COG0131	Imidazoleglycerol-phosphate dehydratase
FH779_RS15350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FH779_RS15360	COG0107	imidazoleglycerol-phosphate synthase activity
FH779_RS15365	COG0140	phosphoribosyl-ATP diphosphatase activity
FH779_RS15365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FH779_RS15385	COG2827	Endonuclease containing a URI domain
FH779_RS15390	COG1477	protein flavinylation
FH779_RS15435	COG1733	regulation of RNA biosynthetic process
FH779_RS15450	COG1418	mRNA catabolic process
FH779_RS15455	COG0228	four-way junction DNA binding
FH779_RS15460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FH779_RS15465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FH779_RS15475	COG2003	Belongs to the UPF0758 family
FH779_RS15525	COG1011	Hydrolase
FH779_RS15560	COG0124	histidyl-tRNA synthetase
FH779_RS15565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FH779_RS15585	COG4206	TonB-dependent receptor
FH779_RS15585	COG1629	transport
FH779_RS15595	COG4771	TonB-dependent receptor
FH779_RS15615	COG0159	tryptophan synthase activity
FH779_RS15620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FH779_RS15630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FH779_RS15630	COG3320	Male sterility
FH779_RS15635	COG0598	Magnesium transport protein CorA
FH779_RS15640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FH779_RS15655	COG0584	glycerophosphoryl diester phosphodiesterase
FH779_RS15660	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FH779_RS15665	COG1705	Flagellar rod assembly protein muramidase FlgJ
FH779_RS15665	COG1388	LysM domain
FH779_RS15685	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FH779_RS15690	COG0424	maF-like protein
FH779_RS15695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FH779_RS15705	COG0456	acetyltransferase
FH779_RS15710	COG3530	Putative quorum-sensing-regulated virulence factor
FH779_RS15720	COG0193	aminoacyl-tRNA hydrolase activity
FH779_RS15725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FH779_RS15730	COG0189	ligase activity
FH779_RS15785	COG1247	-acetyltransferase
FH779_RS15795	COG0489	protein tyrosine kinase activity
FH779_RS15800	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FH779_RS15810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FH779_RS15845	COG0586	Pfam SNARE associated Golgi protein
FH779_RS15850	COG0586	Pfam SNARE associated Golgi protein
FH779_RS15855	COG0792	nuclease activity
FH779_RS15860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FH779_RS15865	COG1619	proteins homologs of microcin C7 resistance protein MccF
FH779_RS15880	COG0157	Belongs to the NadC ModD family
FH779_RS15890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FH779_RS15895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FH779_RS15905	COG0284	orotidine-5'-phosphate decarboxylase activity
FH779_RS15905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FH779_RS15915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FH779_RS15935	COG0668	transmembrane transport
FH779_RS15945	COG0343	queuine tRNA-ribosyltransferase activity
FH779_RS15960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FH779_RS15965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FH779_RS15970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FH779_RS15975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FH779_RS15985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FH779_RS16020	COG2066	Belongs to the glutaminase family
FH779_RS16025	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FH779_RS16040	COG0668	transmembrane transport
FH779_RS16045	COG0428	transporter
FH779_RS16070	COG0321	lipoyl(octanoyl) transferase activity
FH779_RS16070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FH779_RS16085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FH779_RS16090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FH779_RS16100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FH779_RS16140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FH779_RS16145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FH779_RS16160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FH779_RS16180	COG1132	(ABC) transporter
FH779_RS16190	COG1045	serine acetyltransferase
FH779_RS16200	COG0542	response to heat
FH779_RS16210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FH779_RS16220	COG1595	DNA-templated transcription, initiation
FH779_RS16235	COG0658	competence protein
FH779_RS16235	COG2333	competence protein COMEC
FH779_RS16245	COG3104	oligopeptide transport
FH779_RS16250	COG3104	oligopeptide transport
FH779_RS16255	COG0823	Involved in the tonB-independent uptake of proteins
FH779_RS16255	COG1506	peptidase
FH779_RS16300	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FH779_RS16315	COG1007	ATP synthesis coupled electron transport
FH779_RS16320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FH779_RS16325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FH779_RS16330	COG0713	ATP synthesis coupled electron transport
FH779_RS16335	COG0839	Belongs to the complex I subunit 6 family
FH779_RS16340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FH779_RS16345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FH779_RS16350	COG1034	ATP synthesis coupled electron transport
FH779_RS16355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FH779_RS16360	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FH779_RS16365	COG0649	NAD binding
FH779_RS16370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FH779_RS16375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FH779_RS16380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FH779_RS16385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FH779_RS16390	COG0129	dihydroxy-acid dehydratase activity
FH779_RS16395	COG0028	Belongs to the TPP enzyme family
FH779_RS16405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FH779_RS16410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FH779_RS16420	COG0083	homoserine kinase activity
FH779_RS16425	COG0527	aspartate kinase activity
FH779_RS16425	COG0460	homoserine dehydrogenase
FH779_RS16455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FH779_RS16460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FH779_RS16485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FH779_RS16490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FH779_RS16515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FH779_RS16520	COG0826	peptidase U32
FH779_RS16540	COG2003	Belongs to the UPF0758 family
FH779_RS16595	COG1012	belongs to the aldehyde dehydrogenase family
FH779_RS16605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FH779_RS16610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FH779_RS16615	COG1774	PSP1 C-terminal conserved region
FH779_RS16625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FH779_RS16635	COG3153	acetyltransferase
FH779_RS16640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FH779_RS16640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FH779_RS16650	COG0330	HflC and HflK could
FH779_RS16655	COG2151	metal-sulfur cluster biosynthetic enzyme
FH779_RS16670	COG0745	RESPONSE REGULATOR receiver
FH779_RS16675	COG5002	protein histidine kinase activity
FH779_RS16685	COG0495	leucyl-tRNA aminoacylation
FH779_RS16690	COG4682	membrane
FH779_RS16705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FH779_RS16710	COG1522	sequence-specific DNA binding
FH779_RS16770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FH779_RS16785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FH779_RS16790	COG0196	riboflavin kinase activity
FH779_RS16810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FH779_RS16820	COG0594	ribonuclease P activity
FH779_RS16830	COG2095	MarC family integral membrane protein
FH779_RS16835	COG3279	Response regulator of the LytR AlgR family
FH779_RS16845	COG2972	Histidine kinase
FH779_RS16870	COG2304	oxidoreductase activity
FH779_RS16890	COG0714	Associated with various cellular activities
FH779_RS16915	COG3842	ATPase activity
FH779_RS16920	COG1129	ABC transporter
FH779_RS16925	COG0126	phosphoglycerate kinase activity
FH779_RS16930	COG0698	ribose 5-phosphate isomerase
FH779_RS16935	COG2502	aspartate--ammonia ligase
FH779_RS16945	COG0557	exoribonuclease II activity
FH779_RS16980	COG2166	iron-sulfur cluster assembly
FH779_RS16985	COG1597	lipid kinase activity
FH779_RS16990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FH779_RS16995	COG2226	methyltransferase
FH779_RS17000	COG1741	Belongs to the pirin family
FH779_RS17010	COG2885	chlorophyll binding
FH779_RS17025	COG0445	tRNA wobble uridine modification
FH779_RS17030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FH779_RS17035	COG1752	Esterase of the alpha-beta hydrolase superfamily
FH779_RS17045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FH779_RS17050	COG1435	thymidine kinase activity
FH779_RS17090	COG3851	Histidine kinase
FH779_RS17170	COG0720	synthase
FH779_RS17175	COG1040	competence protein
FH779_RS17200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FH779_RS17225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FH779_RS17230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FH779_RS17235	COG0297	glycogen (starch) synthase activity
FH779_RS17245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FH779_RS17255	COG5000	phosphorelay sensor kinase activity
FH779_RS17260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FH779_RS17265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FH779_RS17270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FH779_RS17275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FH779_RS17280	COG0571	ribonuclease III activity
FH779_RS17295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FH779_RS17295	COG0662	Cupin 2, conserved barrel domain protein
FH779_RS17300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FH779_RS17310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FH779_RS17320	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FH779_RS17325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FH779_RS17330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FH779_RS17340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FH779_RS17370	COG0438	transferase activity, transferring glycosyl groups
FH779_RS17390	COG5434	Belongs to the glycosyl hydrolase 28 family
FH779_RS17390	COG3420	alginic acid biosynthetic process
FH779_RS17395	COG0367	asparagine synthase
FH779_RS17405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FH779_RS17410	COG0297	glycogen (starch) synthase activity
FH779_RS17440	COG1733	regulation of RNA biosynthetic process
FH779_RS17475	COG3041	Addiction module toxin RelE StbE family
FH779_RS17530	COG0798	PFAM Bile acid sodium symporter