locus-tag	class	description
AL497_RS00045	COG1760	l-serine dehydratase
AL497_RS00095	COG0793	Belongs to the peptidase S41A family
AL497_RS00410	COG3065	identical protein binding
AL497_RS00420	COG1199	ATP-dependent helicase activity
AL497_RS00425	COG0251	oxidation-reduction process
AL497_RS00445	COG1760	l-serine dehydratase
AL497_RS00450	COG2200	EAL domain
AL497_RS00455	COG1253	flavin adenine dinucleotide binding
AL497_RS00460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS00460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS00465	COG3715	PTS system
AL497_RS00470	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS00485	COG2226	methyltransferase
AL497_RS00490	COG0768	penicillin binding
AL497_RS00515	COG1414	Transcriptional regulator
AL497_RS00520	COG2814	Major facilitator Superfamily
AL497_RS00540	COG1956	GAF domain-containing protein
AL497_RS00545	COG2995	paraquat-inducible protein a
AL497_RS00550	COG3008	intermembrane lipid transfer
AL497_RS00575	COG2990	Protein conserved in bacteria
AL497_RS00615	COG1276	copper resistance
AL497_RS00620	COG2372	response to copper ion
AL497_RS00630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS00635	COG1770	oligopeptidase
AL497_RS00640	COG2979	Protein of unknown function (DUF533)
AL497_RS00645	COG3141	response to X-ray
AL497_RS00655	COG0800	Aldolase
AL497_RS00660	COG0129	dihydroxy-acid dehydratase activity
AL497_RS00665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL497_RS00670	COG1737	Transcriptional regulator
AL497_RS00680	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS00685	COG0739	heme binding
AL497_RS00690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL497_RS00700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS00725	COG0494	nUDIX hydrolase
AL497_RS00735	COG1335	isochorismatase
AL497_RS00740	COG1801	Protein of unknown function DUF72
AL497_RS00745	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL497_RS00765	COG3102	Protein conserved in bacteria
AL497_RS00775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS00800	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS00810	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS00815	COG1528	Iron-storage protein
AL497_RS00835	COG1528	Iron-storage protein
AL497_RS00845	COG0814	amino acid
AL497_RS00850	COG3012	SEC-C Motif Domain Protein
AL497_RS00850	COG3318	Belongs to the UPF0149 family
AL497_RS00855	COG3152	Membrane
AL497_RS00860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS00890	COG2197	response regulator
AL497_RS00900	COG2197	response regulator
AL497_RS00905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL497_RS00910	COG1126	abc transporter atp-binding protein
AL497_RS00915	COG0765	amino acid transport
AL497_RS00925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS00930	COG0366	Alpha amylase catalytic
AL497_RS00960	COG5475	Uncharacterized small protein (DUF2158)
AL497_RS00965	COG2354	Protein conserved in bacteria
AL497_RS00970	COG0697	spore germination
AL497_RS00975	COG3727	T/G mismatch-specific endonuclease activity
AL497_RS00980	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL497_RS00985	COG1418	mRNA catabolic process
AL497_RS00995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS01015	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS01035	COG2977	Belongs to the P-Pant transferase superfamily
AL497_RS01050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL497_RS01065	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL497_RS01075	COG1725	Transcriptional regulator
AL497_RS01085	COG0534	Mate efflux family protein
AL497_RS01100	COG0582	viral genome integration into host DNA
AL497_RS01110	COG1121	(ABC) transporter
AL497_RS01115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01120	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS01145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL497_RS01155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL497_RS01160	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS01165	COG1121	(ABC) transporter
AL497_RS01170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01205	COG0523	cobalamin synthesis protein
AL497_RS01235	COG0523	cobalamin synthesis protein
AL497_RS01240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS01250	COG0582	viral genome integration into host DNA
AL497_RS01255	COG1169	isochorismate synthase
AL497_RS01260	COG2814	Major facilitator Superfamily
AL497_RS01265	COG1132	(ABC) transporter
AL497_RS01280	COG3433	isochorismatase activity
AL497_RS01280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS01280	COG2226	methyltransferase
AL497_RS01300	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL497_RS01305	COG4771	TonB-dependent receptor
AL497_RS01365	COG3504	Conjugal transfer protein
AL497_RS01435	COG0154	amidase activity
AL497_RS01465	COG1960	acyl-CoA dehydrogenase activity
AL497_RS01470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS01475	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS01490	COG2197	response regulator
AL497_RS01500	COG2963	transposase activity
AL497_RS01505	COG2801	Transposase and inactivated derivatives
AL497_RS01530	COG3615	Tellurite resistance protein tehB
AL497_RS01535	COG5001	Diguanylate cyclase
AL497_RS01535	COG3300	MHYT domain
AL497_RS01545	COG0477	Major facilitator Superfamily
AL497_RS01550	COG0095	Lipoate-protein ligase
AL497_RS01560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL497_RS01585	COG1289	transmembrane transporter activity
AL497_RS01595	COG1686	Belongs to the peptidase S11 family
AL497_RS01600	COG2925	Exonuclease
AL497_RS01605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL497_RS01610	COG0640	Transcriptional regulator
AL497_RS01615	COG0531	amino acid
AL497_RS01620	COG0583	DNA-binding transcription factor activity
AL497_RS01625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS01635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL497_RS01650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL497_RS01675	COG0438	transferase activity, transferring glycosyl groups
AL497_RS01685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL497_RS01730	COG0438	transferase activity, transferring glycosyl groups
AL497_RS01765	COG2244	polysaccharide biosynthetic process
AL497_RS01770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL497_RS01805	COG1253	flavin adenine dinucleotide binding
AL497_RS01810	COG2982	Protein involved in outer membrane biogenesis
AL497_RS01825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL497_RS01830	COG0443	Heat shock 70 kDa protein
AL497_RS01855	COG2205	protein histidine kinase activity
AL497_RS01860	COG0745	RESPONSE REGULATOR receiver
AL497_RS01865	COG0826	peptidase U32
AL497_RS01880	COG1070	Carbohydrate kinase
AL497_RS01890	COG2390	Transcriptional regulator
AL497_RS01915	COG1830	Aldolase
AL497_RS01920	COG0351	phosphomethylpyrimidine kinase
AL497_RS01945	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL497_RS01955	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL497_RS01965	COG0583	DNA-binding transcription factor activity
AL497_RS01975	COG2252	PERMEase
AL497_RS01980	COG0583	DNA-binding transcription factor activity
AL497_RS01985	COG5455	response to cobalt ion
AL497_RS01995	COG0489	protein tyrosine kinase activity
AL497_RS02005	COG4808	Protein conserved in bacteria
AL497_RS02010	COG4807	Protein conserved in bacteria
AL497_RS02020	COG3275	phosphorelay sensor kinase activity
AL497_RS02025	COG0789	Transcriptional regulator
AL497_RS02030	COG1174	glycine betaine transport
AL497_RS02035	COG1125	glycine betaine transport
AL497_RS02040	COG1174	glycine betaine transport
AL497_RS02045	COG1732	Glycine betaine
AL497_RS02050	COG1472	Belongs to the glycosyl hydrolase 3 family
AL497_RS02055	COG0277	FAD linked oxidase domain protein
AL497_RS02065	COG1686	Belongs to the peptidase S11 family
AL497_RS02075	COG0586	Pfam SNARE associated Golgi protein
AL497_RS02080	COG1538	Outer membrane efflux protein
AL497_RS02090	COG2723	6-phospho-beta-galactosidase activity
AL497_RS02105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL497_RS02110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS02115	COG0625	glutathione transferase activity
AL497_RS02130	COG2271	Major facilitator Superfamily
AL497_RS02135	COG0583	DNA-binding transcription factor activity
AL497_RS02145	COG1346	cytolysis
AL497_RS02155	COG2949	membrane
AL497_RS02165	COG1129	ABC transporter
AL497_RS02180	COG2311	Membrane
AL497_RS02205	COG1393	Belongs to the ArsC family
AL497_RS02210	COG4771	TonB-dependent receptor
AL497_RS02215	COG0833	amino acid
AL497_RS02230	COG0583	DNA-binding transcription factor activity
AL497_RS02235	COG2855	membrane
AL497_RS02245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS02245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS02245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL497_RS02250	COG1105	Belongs to the carbohydrate kinase PfkB family
AL497_RS02275	COG1312	Catalyzes the dehydration of D-mannonate
AL497_RS02280	COG0246	Mannitol dehydrogenase
AL497_RS02285	COG0523	cobalamin synthesis protein
AL497_RS02290	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS02295	COG0791	NLP P60 protein
AL497_RS02300	COG2200	EAL domain
AL497_RS02305	COG4166	transmembrane transport
AL497_RS02310	COG4174	ABC transporter (Permease)
AL497_RS02315	COG4239	(ABC) transporter, permease
AL497_RS02320	COG4172	Belongs to the ABC transporter superfamily
AL497_RS02330	COG2814	Major facilitator Superfamily
AL497_RS02335	COG1187	pseudouridine synthase activity
AL497_RS02340	COG1061	Type III restriction enzyme res subunit
AL497_RS02360	COG0494	nUDIX hydrolase
AL497_RS02365	COG1349	DNA-binding transcription factor activity
AL497_RS02390	COG0628	permease
AL497_RS02405	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS02410	COG2239	Acts as a magnesium transporter
AL497_RS02415	COG4615	Cyclic peptide transporter
AL497_RS02425	COG2169	Transcriptional regulator
AL497_RS02425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL497_RS02440	COG2198	Histidine kinase
AL497_RS02440	COG0642	Histidine kinase
AL497_RS02475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS02480	COG0584	glycerophosphoryl diester phosphodiesterase
AL497_RS02485	COG2271	Major facilitator Superfamily
AL497_RS02490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL497_RS02500	COG0247	lactate metabolic process
AL497_RS02520	COG0642	Histidine kinase
AL497_RS02545	COG0318	PFAM AMP-dependent synthetase and ligase
AL497_RS02570	COG1169	isochorismate synthase
AL497_RS02575	COG2153	protein acetylation
AL497_RS02590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS02595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL497_RS02605	COG0839	Belongs to the complex I subunit 6 family
AL497_RS02650	COG0583	DNA-binding transcription factor activity
AL497_RS02655	COG0436	Aminotransferase
AL497_RS02665	COG0490	domain, Protein
AL497_RS02665	COG0471	metal ion transport
AL497_RS02670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS02700	COG0622	Phosphoesterase
AL497_RS02705	COG0625	glutathione transferase activity
AL497_RS02710	COG0625	glutathione transferase activity
AL497_RS02715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL497_RS02720	COG1090	epimerase
AL497_RS02740	COG4598	ABC transporter
AL497_RS02745	COG4160	amino acid transport
AL497_RS02760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS02765	COG0163	prenyltransferase activity
AL497_RS02770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL497_RS02775	COG1286	toxin biosynthetic process
AL497_RS02780	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL497_RS02785	COG0285	dihydrofolate synthase activity
AL497_RS02795	COG0586	Pfam SNARE associated Golgi protein
AL497_RS02805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL497_RS02820	COG2814	Major facilitator Superfamily
AL497_RS02825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS02840	COG3101	peptidyl-lysine hydroxylation
AL497_RS02845	COG0730	response to heat
AL497_RS02870	COG2062	phosphohistidine phosphatase, SixA
AL497_RS02885	COG3691	Protein conserved in bacteria
AL497_RS02895	COG2853	Lipoprotein
AL497_RS02900	COG2116	formate transmembrane transporter activity
AL497_RS02925	COG0590	tRNA wobble adenosine to inosine editing
AL497_RS02930	COG2807	transmembrane transport
AL497_RS02935	COG0436	Aminotransferase
AL497_RS02940	COG3275	phosphorelay sensor kinase activity
AL497_RS02945	COG3279	Response regulator of the LytR AlgR family
AL497_RS02960	COG3961	Belongs to the TPP enzyme family
AL497_RS02965	COG0667	Aldo Keto reductase
AL497_RS02980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS02985	COG2200	EAL domain
AL497_RS02985	COG2199	diguanylate cyclase activity
AL497_RS03000	COG3415	Transposase
AL497_RS03005	COG3415	Transposase
AL497_RS03045	COG0583	DNA-binding transcription factor activity
AL497_RS03050	COG0385	Bile acid
AL497_RS03055	COG3530	Putative quorum-sensing-regulated virulence factor
AL497_RS03080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS03120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL497_RS03125	COG4208	sulfate ABC transporter
AL497_RS03130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL497_RS03135	COG4150	thiosulfate binding
AL497_RS03140	COG2837	iron assimilation
AL497_RS03160	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS03180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS03185	COG5342	invasion associated locus B
AL497_RS03195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS03195	COG0493	'glutamate synthase
AL497_RS03200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS03205	COG1393	Belongs to the ArsC family
AL497_RS03220	COG0400	carboxylic ester hydrolase activity
AL497_RS03230	COG2321	neutral zinc metallopeptidase
AL497_RS03240	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL497_RS03250	COG2716	regulation of RNA biosynthetic process
AL497_RS03255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL497_RS03260	COG0628	permease
AL497_RS03265	COG4783	chaperone-mediated protein folding
AL497_RS03270	COG1393	Belongs to the ArsC family
AL497_RS03285	COG2233	PERMEase
AL497_RS03295	COG2723	6-phospho-beta-galactosidase activity
AL497_RS03305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL497_RS03315	COG2211	Major facilitator Superfamily
AL497_RS03320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS03335	COG0248	Ppx GppA phosphatase
AL497_RS03340	COG2200	EAL domain
AL497_RS03370	COG0517	IMP dehydrogenase activity
AL497_RS03370	COG0516	GMP reductase activity
AL497_RS03390	COG1645	bacterial-type flagellum-dependent swarming motility
AL497_RS03405	COG2976	Protein conserved in bacteria
AL497_RS03435	COG4953	penicillin-binding protein 1C
AL497_RS03440	COG2373	Large extracellular alpha-helical protein
AL497_RS03445	COG2897	thiosulfate sulfurtransferase activity
AL497_RS03460	COG2975	iron-sulfur cluster assembly
AL497_RS03465	COG0633	Ferredoxin
AL497_RS03485	COG0822	iron-sulfur transferase activity
AL497_RS03510	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL497_RS03515	COG3683	transport system, periplasmic component
AL497_RS03520	COG3711	transcriptional antiterminator
AL497_RS03525	COG2814	Major facilitator Superfamily
AL497_RS03530	COG2259	Doxx family
AL497_RS03540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS03540	COG1017	nitric oxide dioxygenase activity
AL497_RS03545	COG0347	Belongs to the P(II) protein family
AL497_RS03550	COG2204	response regulator
AL497_RS03555	COG3170	Tfp pilus assembly protein FimV
AL497_RS03560	COG2205	protein histidine kinase activity
AL497_RS03565	COG0047	phosphoribosylformylglycinamidine synthase activity
AL497_RS03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL497_RS03580	COG0560	Phosphoserine phosphatase
AL497_RS03585	COG1737	Transcriptional regulator
AL497_RS03590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS03600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL497_RS03620	COG0681	Belongs to the peptidase S26 family
AL497_RS03630	COG3086	response to oxidative stress
AL497_RS03635	COG3026	antisigma factor binding
AL497_RS03640	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AL497_RS03650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL497_RS03660	COG0513	Belongs to the DEAD box helicase family
AL497_RS03675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS03680	COG3118	belongs to the thioredoxin family
AL497_RS03685	COG3148	PFAM DTW domain containing protein
AL497_RS03695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL497_RS03700	COG5544	Lipoprotein
AL497_RS03705	COG0477	Major facilitator Superfamily
AL497_RS03735	COG0542	response to heat
AL497_RS03750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL497_RS03755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL497_RS03760	COG1605	Chorismate mutase
AL497_RS03760	COG0077	Prephenate dehydratase
AL497_RS03770	COG1605	Chorismate mutase
AL497_RS03770	COG0287	Prephenate dehydrogenase
AL497_RS03775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS03785	COG2199	diguanylate cyclase activity
AL497_RS03790	COG2885	chlorophyll binding
AL497_RS03825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL497_RS03830	COG4137	Cytochrome C assembly protein
AL497_RS03835	COG4536	flavin adenine dinucleotide binding
AL497_RS03850	COG0497	DNA recombination
AL497_RS03865	COG2867	negative regulation of translational initiation
AL497_RS03970	COG0740	serine-type endopeptidase activity
AL497_RS04010	COG3772	lysozyme
AL497_RS04100	COG0582	viral genome integration into host DNA
AL497_RS04115	COG0582	viral genome integration into host DNA
AL497_RS04160	COG0210	DNA helicase
AL497_RS04165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL497_RS04185	COG4983	Phage plasmid primase, P4 family domain protein
AL497_RS04190	COG3596	GTP binding
AL497_RS04230	COG2003	Belongs to the UPF0758 family
AL497_RS04255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL497_RS04265	COG2169	Transcriptional regulator
AL497_RS04270	COG0243	molybdopterin cofactor binding
AL497_RS04275	COG3005	denitrification pathway
AL497_RS04280	COG3088	subunit of a heme lyase
AL497_RS04280	COG4235	cytochrome complex assembly
AL497_RS04285	COG4235	cytochrome complex assembly
AL497_RS04285	COG3088	subunit of a heme lyase
AL497_RS04290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL497_RS04295	COG1138	Cytochrome C-type biogenesis protein
AL497_RS04305	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04315	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04320	COG4133	protoheme IX ABC transporter activity
AL497_RS04325	COG0477	Major facilitator Superfamily
AL497_RS04330	COG0583	DNA-binding transcription factor activity
AL497_RS04335	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL497_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS04365	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL497_RS04370	COG0747	negative chemotaxis
AL497_RS04375	COG0601	transmembrane transport
AL497_RS04380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS04385	COG0444	Belongs to the ABC transporter superfamily
AL497_RS04390	COG4608	Belongs to the ABC transporter superfamily
AL497_RS04400	COG3284	Transcriptional regulator
AL497_RS04405	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS04410	COG0583	DNA-binding transcription factor activity
AL497_RS04420	COG0640	Transcriptional regulator
AL497_RS04425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL497_RS04455	COG4575	ribosome binding
AL497_RS04465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS04470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL497_RS04480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL497_RS04485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL497_RS04495	COG4176	ABC-type proline glycine betaine transport system permease component
AL497_RS04505	COG1846	Transcriptional regulator
AL497_RS04510	COG1566	PFAM secretion protein HlyD family protein
AL497_RS04515	COG2814	Major facilitator Superfamily
AL497_RS04520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL497_RS04540	COG1238	metal cluster binding
AL497_RS04545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS04550	COG2823	Periplasmic or secreted lipoprotein
AL497_RS04580	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL497_RS04600	COG1546	Belongs to the CinA family
AL497_RS04605	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS04610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS04620	COG2951	lytic endotransglycosylase activity
AL497_RS04625	COG3730	PTS system glucitol sorbitol-specific
AL497_RS04630	COG3732	PTS system glucitol sorbitol-specific
AL497_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS04645	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS04650	COG1349	DNA-binding transcription factor activity
AL497_RS04675	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AL497_RS04680	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL497_RS04685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS04690	COG1609	Transcriptional regulator
AL497_RS04695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS04695	COG1263	PTS System
AL497_RS04700	COG2723	6-phospho-beta-galactosidase activity
AL497_RS04705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL497_RS04715	COG3260	NADH ubiquinone oxidoreductase 20
AL497_RS04720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS04725	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL497_RS04725	COG3261	NADH dehydrogenase
AL497_RS04730	COG0650	Formate hydrogenlyase subunit 4
AL497_RS04735	COG0651	ATP synthesis coupled electron transport
AL497_RS04740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS04755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL497_RS04760	COG0298	carbon dioxide binding
AL497_RS04765	COG0409	Hydrogenase expression formation protein
AL497_RS04770	COG0309	Hydrogenase expression formation protein (HypE)
AL497_RS04785	COG1121	(ABC) transporter
AL497_RS04790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS04795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS04805	COG0583	DNA-binding transcription factor activity
AL497_RS04810	COG0679	Auxin Efflux Carrier
AL497_RS04830	COG3720	iron ion transport
AL497_RS04835	COG4558	Periplasmic binding protein
AL497_RS04840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS04875	COG3121	Chaperone
AL497_RS04890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS04895	COG0163	prenyltransferase activity
AL497_RS04915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL497_RS04920	COG1388	LysM domain
AL497_RS04920	COG4942	peptidase
AL497_RS04950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL497_RS04980	COG2234	aminopeptidase activity
AL497_RS05000	COG0720	synthase
AL497_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05010	COG0602	queuosine metabolic process
AL497_RS05030	COG3956	TIGRFAM MazG family protein
AL497_RS05035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL497_RS05045	COG2205	protein histidine kinase activity
AL497_RS05045	COG3437	response regulator, receiver
AL497_RS05045	COG3850	Histidine kinase
AL497_RS05045	COG4999	Histidine kinase
AL497_RS05050	COG1929	Belongs to the glycerate kinase type-1 family
AL497_RS05055	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS05060	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS05065	COG2271	Major facilitator Superfamily
AL497_RS05070	COG0716	FMN binding
AL497_RS05075	COG0564	pseudouridine synthase activity
AL497_RS05080	COG3098	single-species biofilm formation
AL497_RS05095	COG1611	Belongs to the LOG family
AL497_RS05100	COG0814	amino acid
AL497_RS05105	COG1760	l-serine dehydratase
AL497_RS05120	COG2363	Small membrane protein
AL497_RS05125	COG0583	DNA-binding transcription factor activity
AL497_RS05130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL497_RS05135	COG2166	iron-sulfur cluster assembly
AL497_RS05140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL497_RS05145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL497_RS05165	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS05170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL497_RS05170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL497_RS05175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL497_RS05180	COG1074	ATP-dependent DNA helicase activity
AL497_RS05185	COG1025	Belongs to the peptidase M16 family
AL497_RS05190	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL497_RS05205	COG4795	General secretion pathway protein
AL497_RS05210	COG2165	general secretion pathway protein
AL497_RS05240	COG0861	Integral membrane protein TerC family
AL497_RS05250	COG0667	Aldo Keto reductase
AL497_RS05265	COG1609	Transcriptional regulator
AL497_RS05275	COG1609	Transcriptional regulator
AL497_RS05285	COG0583	DNA-binding transcription factor activity
AL497_RS05290	COG1794	racemase activity, acting on amino acids and derivatives
AL497_RS05315	COG2814	Major facilitator Superfamily
AL497_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05325	COG0183	Belongs to the thiolase family
AL497_RS05330	COG0583	DNA-binding transcription factor activity
AL497_RS05340	COG0814	amino acid
AL497_RS05345	COG0667	Aldo Keto reductase
AL497_RS05360	COG0640	Transcriptional regulator
AL497_RS05375	COG0697	spore germination
AL497_RS05380	COG1846	Transcriptional regulator
AL497_RS05390	COG0154	amidase activity
AL497_RS05395	COG1960	acyl-CoA dehydrogenase activity
AL497_RS05405	COG4638	Rieske (2fe-2S)
AL497_RS05415	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS05440	COG3188	usher protein
AL497_RS05445	COG3121	Chaperone
AL497_RS05450	COG3539	Fimbrial protein
AL497_RS05470	COG0582	viral genome integration into host DNA
AL497_RS05475	COG4974	Belongs to the 'phage' integrase family
AL497_RS05485	COG3539	Fimbrial protein
AL497_RS05490	COG3121	Chaperone
AL497_RS05495	COG3188	usher protein
AL497_RS05500	COG3539	Fimbrial protein
AL497_RS05505	COG3539	Fimbrial protein
AL497_RS05510	COG3539	Fimbrial protein
AL497_RS05520	COG2388	GCN5-related N-acetyl-transferase
AL497_RS05525	COG3592	Divergent 4Fe-4S mono-cluster
AL497_RS05540	COG1289	transmembrane transporter activity
AL497_RS05545	COG1538	Outer membrane efflux protein
AL497_RS05555	COG1982	Orn Lys Arg decarboxylase major
AL497_RS05560	COG0531	amino acid
AL497_RS05575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL497_RS05595	COG2271	Major facilitator Superfamily
AL497_RS05600	COG0483	inositol monophosphate 1-phosphatase activity
AL497_RS05605	COG1609	Transcriptional regulator
AL497_RS05610	COG0753	catalase activity
AL497_RS05620	COG0531	amino acid
AL497_RS05630	COG0124	histidyl-tRNA synthetase
AL497_RS05635	COG0124	histidyl-tRNA synthetase
AL497_RS05650	COG3539	Fimbrial protein
AL497_RS05660	COG3121	Chaperone
AL497_RS05665	COG3188	usher protein
AL497_RS05675	COG3539	Fimbrial protein
AL497_RS05705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS05715	COG4942	peptidase
AL497_RS05720	COG0583	DNA-binding transcription factor activity
AL497_RS05725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS05735	COG1811	Na channel or pump
AL497_RS05755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL497_RS05765	COG4974	Belongs to the 'phage' integrase family
AL497_RS05770	COG0716	FMN binding
AL497_RS05780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL497_RS05790	COG1272	protein, Hemolysin III
AL497_RS05800	COG1737	Transcriptional regulator
AL497_RS05805	COG2723	6-phospho-beta-galactosidase activity
AL497_RS05825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL497_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS05855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS05860	COG0006	proline dipeptidase activity
AL497_RS05880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL497_RS05885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL497_RS05900	COG2968	Membrane
AL497_RS05905	COG1279	arginine transmembrane transporter activity
AL497_RS05910	COG0668	transmembrane transport
AL497_RS05915	COG0583	DNA-binding transcription factor activity
AL497_RS05925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS05930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS05935	COG2271	Major facilitator Superfamily
AL497_RS05940	COG0549	Belongs to the carbamate kinase family
AL497_RS05945	COG0191	fructose-bisphosphate aldolase activity
AL497_RS05960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS05965	COG0501	Belongs to the peptidase M48B family
AL497_RS05985	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL497_RS05990	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS06020	COG1414	Transcriptional regulator
AL497_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS06040	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS06075	COG2814	Major facilitator Superfamily
AL497_RS06085	COG2356	endonuclease I
AL497_RS06090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL497_RS06095	COG0189	ligase activity
AL497_RS06110	COG2197	response regulator
AL497_RS06115	COG2805	Type II/IV secretion system protein
AL497_RS06120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL497_RS06125	COG0762	integral membrane protein
AL497_RS06140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL497_RS06155	COG4214	carbohydrate transport
AL497_RS06165	COG3171	Protein conserved in bacteria
AL497_RS06175	COG1194	a g-specific adenine glycosylase
AL497_RS06190	COG2211	Major facilitator Superfamily
AL497_RS06195	COG1982	Orn Lys Arg decarboxylase major
AL497_RS06205	COG1811	Na channel or pump
AL497_RS06225	COG2731	YhcH YjgK YiaL family protein
AL497_RS06250	COG2186	Transcriptional regulator
AL497_RS06265	COG2382	esterase
AL497_RS06275	COG4771	TonB-dependent receptor
AL497_RS06285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS06300	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS06300	COG4977	sequence-specific DNA binding
AL497_RS06305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS06310	COG3753	Protein conserved in bacteria
AL497_RS06315	COG1652	LysM domain
AL497_RS06320	COG0583	DNA-binding transcription factor activity
AL497_RS06330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS06335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL497_RS06350	COG2072	flavoprotein involved in K transport
AL497_RS06355	COG0583	DNA-binding transcription factor activity
AL497_RS06360	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS06380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS06385	COG0754	glutathionylspermidine amidase activity
AL497_RS06395	COG0625	glutathione transferase activity
AL497_RS06405	COG0848	biopolymer transport protein
AL497_RS06415	COG0626	cystathionine gamma-synthase activity
AL497_RS06420	COG0586	Pfam SNARE associated Golgi protein
AL497_RS06425	COG2207	Transcriptional regulator
AL497_RS06435	COG1979	alcohol dehydrogenase
AL497_RS06440	COG0656	L-ascorbic acid biosynthetic process
AL497_RS06450	COG1032	radical SAM domain protein
AL497_RS06460	COG0204	Acyl-transferase
AL497_RS06470	COG3111	PFAM Bacterial OB fold (BOF) protein
AL497_RS06485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL497_RS06490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL497_RS06495	COG0187	DNA topoisomerase II activity
AL497_RS06500	COG3150	esterase
AL497_RS06505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL497_RS06510	COG3151	Protein conserved in bacteria
AL497_RS06515	COG0494	nUDIX hydrolase
AL497_RS06530	COG0754	glutathionylspermidine amidase activity
AL497_RS06535	COG3384	dioxygenase
AL497_RS06545	COG2960	long-chain fatty acid transporting porin activity
AL497_RS06565	COG3025	triphosphatase activity
AL497_RS06570	COG4991	sh3 domain protein
AL497_RS06585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL497_RS06595	COG0477	Major facilitator Superfamily
AL497_RS06605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL497_RS06610	COG0358	DNA primase activity
AL497_RS06620	COG3663	DNA glycosylase
AL497_RS06660	COG3119	arylsulfatase activity
AL497_RS06665	COG0641	radical SAM
AL497_RS06670	COG0714	Associated with various cellular activities
AL497_RS06705	COG0641	radical SAM
AL497_RS06730	COG2376	Dihydroxyacetone kinase
AL497_RS06735	COG1461	Dihydroxyacetone kinase
AL497_RS06750	COG2375	cellular response to nickel ion
AL497_RS06755	COG1695	Transcriptional regulator
AL497_RS06765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL497_RS06770	COG1609	Transcriptional regulator
AL497_RS06775	COG3250	beta-galactosidase activity
AL497_RS06780	COG2731	YhcH YjgK YiaL family protein
AL497_RS06785	COG0531	amino acid
AL497_RS06790	COG0531	amino acid
AL497_RS06800	COG3408	Glycogen debranching enzyme
AL497_RS06800	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL497_RS06845	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL497_RS06845	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS06855	COG1451	nucleotide metabolic process
AL497_RS06860	COG0673	inositol 2-dehydrogenase activity
AL497_RS06865	COG0861	Integral membrane protein TerC family
AL497_RS06880	COG2721	sulfolactate sulfo-lyase activity
AL497_RS06890	COG2271	Major facilitator Superfamily
AL497_RS06895	COG2186	Transcriptional regulator
AL497_RS06900	COG0586	Pfam SNARE associated Golgi protein
AL497_RS06910	COG1422	Protein of unknown function (DUF1090)
AL497_RS06915	COG4575	ribosome binding
AL497_RS06920	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL497_RS06935	COG2259	Doxx family
AL497_RS06940	COG0435	Glutathione S-transferase
AL497_RS06945	COG3152	Membrane
AL497_RS06950	COG0583	DNA-binding transcription factor activity
AL497_RS06955	COG1741	Belongs to the pirin family
AL497_RS06965	COG0668	transmembrane transport
AL497_RS06975	COG1929	Belongs to the glycerate kinase type-1 family
AL497_RS06980	COG2084	Dehydrogenase
AL497_RS06990	COG2721	sulfolactate sulfo-lyase activity
AL497_RS06995	COG1349	DNA-binding transcription factor activity
AL497_RS07005	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS07015	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS07020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL497_RS07030	COG2222	sugar isomerase
AL497_RS07045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL497_RS07065	COG2823	Periplasmic or secreted lipoprotein
AL497_RS07070	COG0701	Predicted permease
AL497_RS07075	COG0702	epimerase
AL497_RS07080	COG0693	protein deglycase activity
AL497_RS07095	COG3153	acetyltransferase
AL497_RS07100	COG3154	lipid carrier protein
AL497_RS07105	COG0826	peptidase U32
AL497_RS07110	COG0826	peptidase U32
AL497_RS07115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS07120	COG0814	amino acid
AL497_RS07160	COG0195	Participates in both transcription termination and antitermination
AL497_RS07200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL497_RS07210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL497_RS07215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL497_RS07225	COG1534	Rna-binding protein
AL497_RS07235	COG2027	D-alanyl-D-alanine carboxypeptidase
AL497_RS07245	COG0697	spore germination
AL497_RS07260	COG0142	geranyltranstransferase activity
AL497_RS07265	COG3423	Transcriptional regulator
AL497_RS07275	COG5007	Belongs to the BolA IbaG family
AL497_RS07280	COG3113	response to antibiotic
AL497_RS07285	COG2854	intermembrane phospholipid transfer
AL497_RS07290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL497_RS07295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL497_RS07300	COG1127	ABC transporter
AL497_RS07305	COG0530	calcium, potassium:sodium antiporter activity
AL497_RS07315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL497_RS07320	COG3117	lipopolysaccharide transmembrane transporter activity
AL497_RS07325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL497_RS07330	COG1137	ATPase activity
AL497_RS07335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL497_RS07340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL497_RS07345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL497_RS07365	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL497_RS07370	COG5002	protein histidine kinase activity
AL497_RS07370	COG0784	Response regulator, receiver
AL497_RS07370	COG2198	Histidine kinase
AL497_RS07385	COG0069	glutamate synthase activity
AL497_RS07385	COG0070	glutamate synthase
AL497_RS07385	COG0067	glutamate synthase
AL497_RS07390	COG0493	'glutamate synthase
AL497_RS07395	COG2969	positive regulation of protein catabolic process
AL497_RS07400	COG0625	glutathione transferase activity
AL497_RS07415	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL497_RS07420	COG3105	Protein conserved in bacteria
AL497_RS07425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL497_RS07430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL497_RS07460	COG2732	(Barnase) inhibitor
AL497_RS07465	COG1289	transmembrane transporter activity
AL497_RS07480	COG0583	DNA-binding transcription factor activity
AL497_RS07485	COG0312	modulator of DNA gyrase
AL497_RS07490	COG3164	Protein of unknown function
AL497_RS07505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL497_RS07510	COG1792	Involved in formation and maintenance of cell shape
AL497_RS07515	COG1077	Cell shape determining protein MreB Mrl
AL497_RS07520	COG2199	diguanylate cyclase activity
AL497_RS07520	COG2200	EAL domain
AL497_RS07525	COG0604	alcohol dehydrogenase
AL497_RS07540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL497_RS07545	COG0511	ligase activity, forming carbon-carbon bonds
AL497_RS07550	COG0439	Biotin carboxylase
AL497_RS07555	COG3924	membrane
AL497_RS07560	COG4145	pantothenate transmembrane transporter activity
AL497_RS07580	COG1309	transcriptional regulator
AL497_RS07585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS07590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS07630	COG2850	peptidyl-arginine hydroxylation
AL497_RS07635	COG5002	protein histidine kinase activity
AL497_RS07640	COG0745	RESPONSE REGULATOR receiver
AL497_RS07645	COG1538	Outer membrane efflux protein
AL497_RS07650	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS07655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS07660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS07740	COG0582	viral genome integration into host DNA
AL497_RS07750	COG0288	reversible hydration of carbon dioxide
AL497_RS07755	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS07760	COG1064	alcohol dehydrogenase
AL497_RS07765	COG1175	transmembrane transport
AL497_RS07770	COG0395	ABC-type sugar transport system, permease component
AL497_RS07775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL497_RS07780	COG3842	ATPase activity
AL497_RS07790	COG2814	Major facilitator Superfamily
AL497_RS07800	COG1082	Xylose isomerase domain protein TIM barrel
AL497_RS07810	COG3962	Belongs to the TPP enzyme family
AL497_RS07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS07820	COG0837	glucose binding
AL497_RS07820	COG1737	Transcriptional regulator
AL497_RS07825	COG3718	enzyme involved in inositol metabolism
AL497_RS07840	COG0433	COG0433 Predicted ATPase
AL497_RS07850	COG0795	lipopolysaccharide-transporting ATPase activity
AL497_RS07855	COG0795	lipopolysaccharide-transporting ATPase activity
AL497_RS07865	COG2927	DNA polymerase III (CHI subunit)
AL497_RS07870	COG0525	valine-tRNA ligase activity
AL497_RS07890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL497_RS07895	COG2731	YhcH YjgK YiaL family protein
AL497_RS07910	COG0251	oxidation-reduction process
AL497_RS07915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AL497_RS07930	COG1263	PTS System
AL497_RS07930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS07935	COG0366	Alpha amylase catalytic
AL497_RS07940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS07945	COG1486	melibiose metabolic process
AL497_RS07965	COG0602	queuosine metabolic process
AL497_RS07970	COG3711	transcriptional antiterminator
AL497_RS07970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07975	COG2706	6-phosphogluconolactonase activity
AL497_RS07990	COG3964	amidohydrolase
AL497_RS08025	COG0312	modulator of DNA gyrase
AL497_RS08040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL497_RS08050	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS08055	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS08060	COG1129	ABC transporter
AL497_RS08065	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS08075	COG2105	PFAM AIG2 family protein
AL497_RS08080	COG2911	Protein conserved in bacteria
AL497_RS08085	COG0729	surface antigen
AL497_RS08095	COG1253	flavin adenine dinucleotide binding
AL497_RS08105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL497_RS08120	COG1733	regulation of RNA biosynthetic process
AL497_RS08125	COG0702	epimerase
AL497_RS08135	COG0697	spore germination
AL497_RS08145	COG1113	amino acid transport
AL497_RS08150	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS08155	COG3061	Opacity-associated protein A
AL497_RS08165	COG0359	binds to the 23S rRNA
AL497_RS08170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL497_RS08175	COG2965	DNA replication, synthesis of RNA primer
AL497_RS08235	COG1073	alpha beta
AL497_RS08240	COG3650	response to hydrogen peroxide
AL497_RS08250	COG1960	acyl-CoA dehydrogenase activity
AL497_RS08255	COG0477	Major facilitator Superfamily
AL497_RS08260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS08265	COG0557	exoribonuclease II activity
AL497_RS08280	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL497_RS08285	COG0330	HflC and HflK could
AL497_RS08290	COG0330	HflC and HflK could
AL497_RS08295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL497_RS08315	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS08320	COG0802	atpase or kinase
AL497_RS08325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL497_RS08325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL497_RS08330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL497_RS08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS08370	COG3264	Mechanosensitive ion channel
AL497_RS08370	COG1511	domain protein
AL497_RS08385	COG1053	succinate dehydrogenase
AL497_RS08390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL497_RS08410	COG2076	Multidrug Resistance protein
AL497_RS08415	COG5510	response to toxic substance
AL497_RS08425	COG1509	lysine 2,3-aminomutase activity
AL497_RS08480	COG0459	protein refolding
AL497_RS08490	COG0531	amino acid
AL497_RS08495	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL497_RS08500	COG1027	Aspartate ammonia-lyase
AL497_RS08520	COG1309	transcriptional regulator
AL497_RS08545	COG0457	Tetratricopeptide repeat
AL497_RS08550	COG1649	PFAM Uncharacterised BCR, COG1649
AL497_RS08550	COG0726	polysaccharide deacetylase
AL497_RS08555	COG1215	transferase activity, transferring glycosyl groups
AL497_RS08570	COG0861	Integral membrane protein TerC family
AL497_RS08600	COG1486	melibiose metabolic process
AL497_RS08605	COG2169	Transcriptional regulator
AL497_RS08620	COG2824	Alkylphosphonate utilization operon protein PhnA
AL497_RS08625	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL497_RS08630	COG2188	Transcriptional regulator
AL497_RS08635	COG3624	Phosphonate C-P lyase system protein PhnG
AL497_RS08640	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL497_RS08645	COG3626	phosphonate metabolism
AL497_RS08650	COG3627	carbon phosphorus lyase activity
AL497_RS08655	COG4107	phosphonate C-P lyase system protein PhnK
AL497_RS08660	COG4778	phosphonate C-P lyase system protein PhnL
AL497_RS08665	COG3454	Phosphonate metabolism
AL497_RS08675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL497_RS08685	COG4191	Histidine kinase
AL497_RS08685	COG0784	Response regulator, receiver
AL497_RS08690	COG1129	ABC transporter
AL497_RS08695	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS08710	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS08715	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS08720	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL497_RS08725	COG1301	dicarboxylic acid transport
AL497_RS08730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL497_RS08735	COG3162	membrane
AL497_RS08745	COG3539	Fimbrial protein
AL497_RS08750	COG3539	Fimbrial protein
AL497_RS08765	COG3539	Fimbrial protein
AL497_RS08770	COG1346	cytolysis
AL497_RS08780	COG0583	DNA-binding transcription factor activity
AL497_RS08785	COG0025	NhaP-type Na H and K H
AL497_RS08790	COG2252	PERMEase
AL497_RS08795	COG0625	glutathione transferase activity
AL497_RS08800	COG0789	Transcriptional regulator
AL497_RS08810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL497_RS08825	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL497_RS08850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL497_RS08865	COG2315	Protein conserved in bacteria
AL497_RS08870	COG0432	Pfam Uncharacterised protein family UPF0047
AL497_RS08880	COG1448	Aminotransferase
AL497_RS08885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL497_RS08890	COG0305	Participates in initiation and elongation during chromosome replication
AL497_RS08905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL497_RS08915	COG0735	belongs to the Fur family
AL497_RS08920	COG3237	CsbD-like
AL497_RS08925	COG0534	Mate efflux family protein
AL497_RS08935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL497_RS08960	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS09005	COG0251	oxidation-reduction process
AL497_RS09010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL497_RS09020	COG0527	aspartate kinase activity
AL497_RS09025	COG3541	Predicted nucleotidyltransferase
AL497_RS09030	COG1690	Belongs to the RtcB family
AL497_RS09040	COG4650	regulator
AL497_RS09065	COG1187	pseudouridine synthase activity
AL497_RS09080	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL497_RS09085	COG0646	methionine synthase
AL497_RS09085	COG1410	methionine synthase
AL497_RS09105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL497_RS09150	COG0151	Belongs to the GarS family
AL497_RS09160	COG4191	Histidine kinase
AL497_RS09200	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL497_RS09215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL497_RS09220	COG2104	thiamine diphosphate biosynthetic process
AL497_RS09235	COG3706	GGDEF domain
AL497_RS09245	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS09250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL497_RS09285	COG0250	Participates in transcription elongation, termination and antitermination
AL497_RS09395	COG0583	DNA-binding transcription factor activity
AL497_RS09410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL497_RS09425	COG3443	Belongs to the bacterial solute-binding protein 9 family
AL497_RS09430	COG2207	Transcriptional regulator
AL497_RS09440	COG0371	Dehydrogenase
AL497_RS09445	COG0697	spore germination
AL497_RS09455	COG0527	aspartate kinase activity
AL497_RS09455	COG0460	homoserine dehydrogenase
AL497_RS09460	COG0626	cystathionine gamma-synthase activity
AL497_RS09475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL497_RS09480	COG1609	Transcriptional regulator
AL497_RS09485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL497_RS09500	COG1575	Belongs to the MenA family. Type 1 subfamily
AL497_RS09520	COG3678	ATP-independent chaperone mediated protein folding
AL497_RS09525	COG0745	RESPONSE REGULATOR receiver
AL497_RS09530	COG2205	protein histidine kinase activity
AL497_RS09535	COG2258	MOSC domain
AL497_RS09540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL497_RS09580	COG1454	alcohol dehydrogenase
AL497_RS09590	COG2271	Major facilitator Superfamily
AL497_RS09595	COG2731	YhcH YjgK YiaL family protein
AL497_RS09600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS09605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS09615	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL497_RS09635	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS09635	COG0243	molybdopterin cofactor binding
AL497_RS09640	COG0243	molybdopterin cofactor binding
AL497_RS09640	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS09645	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS09650	COG2864	formate dehydrogenase
AL497_RS09660	COG0657	acetylesterase activity
AL497_RS09665	COG0456	acetyltransferase
AL497_RS09680	COG1011	Hydrolase
AL497_RS09695	COG3852	Histidine kinase
AL497_RS09705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL497_RS09725	COG0204	Acyl-transferase
AL497_RS09735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL497_RS09740	COG3084	Protein conserved in bacteria
AL497_RS09750	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL497_RS09785	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AL497_RS09795	COG1739	Uncharacterized protein family UPF0029
AL497_RS09835	COG0805	protein transport
AL497_RS09845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL497_RS09855	COG3165	ubiquinone biosynthetic process from chorismate
AL497_RS09885	COG0583	DNA-binding transcription factor activity
AL497_RS09890	COG0697	spore germination
AL497_RS09895	COG0561	phosphatase activity
AL497_RS09900	COG2267	carboxylic ester hydrolase activity
AL497_RS09905	COG1280	lysine exporter protein (LysE YggA)
AL497_RS09915	COG1280	lysine exporter protein (LysE YggA)
AL497_RS09930	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS09945	COG0210	DNA helicase
AL497_RS09950	COG1011	Hydrolase
AL497_RS09980	COG3072	Adenylate cyclase
AL497_RS09990	COG1587	Uroporphyrinogen-III synthase
AL497_RS09995	COG2959	enzyme of heme biosynthesis
AL497_RS10000	COG3071	HemY protein
AL497_RS10050	COG2244	polysaccharide biosynthetic process
AL497_RS10055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL497_RS10060	COG0456	acetyltransferase
AL497_RS10065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL497_RS10070	COG1088	dTDP-glucose 4,6-dehydratase activity
AL497_RS10075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL497_RS10080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL497_RS10090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL497_RS10095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL497_RS10100	COG3118	belongs to the thioredoxin family
AL497_RS10115	COG0583	DNA-binding transcription factor activity
AL497_RS10125	COG1811	Na channel or pump
AL497_RS10135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS10140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS10150	COG0583	DNA-binding transcription factor activity
AL497_RS10155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL497_RS10165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL497_RS10170	COG3978	acetolactate synthase activity
AL497_RS10180	COG0606	chelatase, subunit chli
AL497_RS10185	COG3085	chromosome segregation
AL497_RS10230	COG2186	Transcriptional regulator
AL497_RS10235	COG0477	Major facilitator Superfamily
AL497_RS10240	COG1609	Transcriptional regulator
AL497_RS10245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS10255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS10260	COG1129	ABC transporter
AL497_RS10290	COG1522	sequence-specific DNA binding
AL497_RS10295	COG0716	FMN binding
AL497_RS10310	COG3312	ion transport
AL497_RS10345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL497_RS10350	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL497_RS10360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL497_RS10365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL497_RS10370	COG0573	inorganic phosphate transmembrane transporter activity
AL497_RS10375	COG0581	inorganic phosphate transmembrane transporter activity
AL497_RS10385	COG0704	Plays a role in the regulation of phosphate uptake
AL497_RS10400	COG2382	esterase
AL497_RS10405	COG0363	glucosamine-6-phosphate deaminase activity
AL497_RS10410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS10415	COG2252	PERMEase
AL497_RS10420	COG0431	NADPH-dependent FMN reductase
AL497_RS10425	COG2091	lysine biosynthetic process via aminoadipic acid
AL497_RS10460	COG0592	DNA-directed DNA polymerase activity
AL497_RS10470	COG0187	DNA topoisomerase II activity
AL497_RS10475	COG0561	phosphatase activity
AL497_RS10490	COG2186	Transcriptional regulator
AL497_RS10495	COG3734	2-keto-3-deoxy-galactonokinase
AL497_RS10500	COG0800	Aldolase
AL497_RS10510	COG2271	Major facilitator Superfamily
AL497_RS10515	COG0823	Involved in the tonB-independent uptake of proteins
AL497_RS10520	COG5645	(Lipo)protein
AL497_RS10540	COG2188	Transcriptional regulator
AL497_RS10555	COG2149	membrane
AL497_RS10575	COG2610	gluconate transmembrane transporter activity
AL497_RS10580	COG0583	DNA-binding transcription factor activity
AL497_RS10585	COG2814	Major facilitator Superfamily
AL497_RS10605	COG0028	Belongs to the TPP enzyme family
AL497_RS10610	COG0440	acetolactate synthase activity
AL497_RS10615	COG2197	response regulator
AL497_RS10625	COG2271	Major facilitator Superfamily
AL497_RS10655	COG2188	Transcriptional regulator
AL497_RS10685	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS10690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS10690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS10700	COG1609	Transcriptional regulator
AL497_RS10725	COG0697	spore germination
AL497_RS10775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS10790	COG1263	PTS System
AL497_RS10790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS10795	COG1464	Belongs to the NlpA lipoprotein family
AL497_RS10805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL497_RS10815	COG1064	alcohol dehydrogenase
AL497_RS10830	COG3311	Transcriptional regulator
AL497_RS10835	COG1569	PIN domain
AL497_RS10865	COG1501	Belongs to the glycosyl hydrolase 31 family
AL497_RS10870	COG3711	transcriptional antiterminator
AL497_RS10875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS10875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS10875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS10880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS10885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS10885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS10895	COG0191	fructose-bisphosphate aldolase activity
AL497_RS10900	COG1940	carbohydrate kinase activity
AL497_RS10915	COG1486	melibiose metabolic process
AL497_RS10920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS10920	COG1263	PTS System
AL497_RS10925	COG2982	Protein involved in outer membrane biogenesis
AL497_RS10930	COG2233	PERMEase
AL497_RS10935	COG0786	glutamate:sodium symporter activity
AL497_RS10950	COG3074	FtsZ-dependent cytokinesis
AL497_RS10955	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL497_RS10980	COG3152	Membrane
AL497_RS10990	COG1494	fructose-1,6-bisphosphatase
AL497_RS10995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL497_RS11000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS11015	COG0194	GDP metabolic process
AL497_RS11025	COG2194	sulfuric ester hydrolase activity
AL497_RS11030	COG2860	membrane
AL497_RS11035	COG1561	YicC-like family, N-terminal region
AL497_RS11060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL497_RS11070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL497_RS11095	COG1519	Transferase
AL497_RS11110	COG1216	Glycosyl transferase, family 2
AL497_RS11125	COG0438	transferase activity, transferring glycosyl groups
AL497_RS11130	COG0859	PFAM glycosyl transferase family 9
AL497_RS11135	COG0859	PFAM glycosyl transferase family 9
AL497_RS11150	COG0156	8-amino-7-oxononanoate synthase activity
AL497_RS11165	COG0463	Glycosyl transferase, family 2
AL497_RS11170	COG2861	carbohydrate metabolic process
AL497_RS11175	COG4942	peptidase
AL497_RS11185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL497_RS11190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL497_RS11215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL497_RS11225	COG2186	Transcriptional regulator
AL497_RS11245	COG3722	fumarate hydratase activity
AL497_RS11265	COG1566	PFAM secretion protein HlyD family protein
AL497_RS11270	COG0625	glutathione transferase activity
AL497_RS11280	COG3276	selenocysteine insertion sequence binding
AL497_RS11285	COG1454	alcohol dehydrogenase
AL497_RS11290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS11295	COG3977	Valine--pyruvate aminotransferase
AL497_RS11300	COG0366	Alpha amylase catalytic
AL497_RS11305	COG2992	FlgJ-related protein
AL497_RS11310	COG2207	Transcriptional regulator
AL497_RS11310	COG1609	Transcriptional regulator
AL497_RS11315	COG4214	carbohydrate transport
AL497_RS11325	COG4213	ABC transporter substrate-binding protein
AL497_RS11340	COG1070	Carbohydrate kinase
AL497_RS11345	COG4682	membrane
AL497_RS11350	COG3274	enterobacterial common antigen metabolic process
AL497_RS11375	COG1278	Cold shock
AL497_RS11380	COG2944	sequence-specific DNA binding
AL497_RS11385	COG2814	Major facilitator Superfamily
AL497_RS11405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS11415	COG1609	Transcriptional regulator
AL497_RS11420	COG2885	chlorophyll binding
AL497_RS11425	COG0243	molybdopterin cofactor binding
AL497_RS11430	COG0456	acetyltransferase
AL497_RS11435	COG2818	Glycosylase
AL497_RS11440	COG5571	outer membrane autotransporter
AL497_RS11445	COG2223	nitrite transmembrane transporter activity
AL497_RS11460	COG0747	negative chemotaxis
AL497_RS11465	COG0601	transmembrane transport
AL497_RS11470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS11475	COG0444	Belongs to the ABC transporter superfamily
AL497_RS11480	COG4608	Belongs to the ABC transporter superfamily
AL497_RS11495	COG2194	sulfuric ester hydrolase activity
AL497_RS11525	COG1215	transferase activity, transferring glycosyl groups
AL497_RS11530	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL497_RS11535	COG0457	Tetratricopeptide repeat
AL497_RS11535	COG3118	belongs to the thioredoxin family
AL497_RS11540	COG2200	EAL domain
AL497_RS11540	COG2199	diguanylate cyclase activity
AL497_RS11550	COG0612	Peptidase, M16
AL497_RS11560	COG2982	Protein involved in outer membrane biogenesis
AL497_RS11565	COG0477	Major facilitator Superfamily
AL497_RS11570	COG1295	ribonuclease BN
AL497_RS11575	COG0583	DNA-binding transcription factor activity
AL497_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS11585	COG2197	response regulator
AL497_RS11595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS11605	COG1454	alcohol dehydrogenase
AL497_RS11610	COG0625	glutathione transferase activity
AL497_RS11615	COG1609	Transcriptional regulator
AL497_RS11620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL497_RS11625	COG2610	gluconate transmembrane transporter activity
AL497_RS11635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL497_RS11640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL497_RS11660	COG1959	2 iron, 2 sulfur cluster binding
AL497_RS11670	COG0589	response to stress
AL497_RS11680	COG0306	phosphate transporter
AL497_RS11685	COG2081	HI0933 family
AL497_RS11690	COG2239	Acts as a magnesium transporter
AL497_RS11710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS11715	COG0601	transmembrane transport
AL497_RS11720	COG0747	negative chemotaxis
AL497_RS11730	COG3479	Phenolic acid decarboxylase
AL497_RS11770	COG2091	lysine biosynthetic process via aminoadipic acid
AL497_RS11775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS11790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS11825	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL497_RS11825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS11835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS11855	COG0477	Major facilitator Superfamily
AL497_RS11865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL497_RS11880	COG3714	YhhN family
AL497_RS11890	COG3776	membrane
AL497_RS11895	COG0742	ribosomal rna small subunit methyltransferase
AL497_RS11900	COG0552	protein localization to endoplasmic reticulum
AL497_RS11905	COG2884	Cell division ATP-binding protein ftsE
AL497_RS11910	COG2177	Part of the ABC transporter FtsEX involved in
AL497_RS11920	COG0683	leucine binding
AL497_RS11930	COG0683	leucine binding
AL497_RS11935	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL497_RS11945	COG0411	ABC transporter
AL497_RS11975	COG0584	glycerophosphoryl diester phosphodiesterase
AL497_RS11985	COG0405	Gamma-glutamyltransferase
AL497_RS11990	COG1247	-acetyltransferase
AL497_RS12000	COG0673	inositol 2-dehydrogenase activity
AL497_RS12005	COG1741	Belongs to the pirin family
AL497_RS12010	COG1609	Transcriptional regulator
AL497_RS12015	COG3265	gluconokinase activity
AL497_RS12020	COG2610	gluconate transmembrane transporter activity
AL497_RS12025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL497_RS12050	COG0058	SHG alpha-glucan phosphorylase activity
AL497_RS12055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL497_RS12070	COG1349	DNA-binding transcription factor activity
AL497_RS12080	COG0058	SHG alpha-glucan phosphorylase activity
AL497_RS12085	COG1640	4-alpha-glucanotransferase
AL497_RS12090	COG2610	gluconate transmembrane transporter activity
AL497_RS12100	COG1040	competence protein
AL497_RS12125	COG1918	ferrous iron import across plasma membrane
AL497_RS12130	COG2183	response to ionizing radiation
AL497_RS12135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL497_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS12150	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS12155	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS12170	COG3254	rhamnose metabolic process
AL497_RS12175	COG0738	Major facilitator superfamily
AL497_RS12200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL497_RS12205	COG1011	Hydrolase
AL497_RS12215	COG0494	nUDIX hydrolase
AL497_RS12220	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL497_RS12240	COG4796	Type ii and iii secretion system protein
AL497_RS12255	COG3266	domain, Protein
AL497_RS12260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL497_RS12265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL497_RS12285	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS12290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL497_RS12295	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS12300	COG0738	Major facilitator superfamily
AL497_RS12310	COG2184	nucleotidyltransferase activity
AL497_RS12320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL497_RS12325	COG1289	transmembrane transporter activity
AL497_RS12335	COG1765	OsmC-like protein
AL497_RS12340	COG3954	Phosphoribulokinase
AL497_RS12350	COG0429	hydrolase of the alpha beta-hydrolase fold
AL497_RS12355	COG0488	(ABC) transporter
AL497_RS12370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL497_RS12375	COG1047	Peptidyl-prolyl cis-trans
AL497_RS12385	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS12390	COG2964	Protein conserved in bacteria
AL497_RS12445	COG0051	transcription antitermination factor activity, RNA binding
AL497_RS12470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL497_RS12485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL497_RS12550	COG0201	protein transport
AL497_RS12560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL497_RS12585	COG0789	Transcriptional regulator
AL497_RS12590	COG3036	rescue of stalled ribosome
AL497_RS12620	COG0758	DNA mediated transformation
AL497_RS12630	COG0551	DNA topoisomerase type I activity
AL497_RS12645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS12675	COG0842	Transport permease protein
AL497_RS12680	COG0842	Transport permease protein
AL497_RS12680	COG1129	ABC transporter
AL497_RS12685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS12690	COG3706	GGDEF domain
AL497_RS12715	COG4869	propanediol catabolic process
AL497_RS12725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS12730	COG1882	Formate acetyltransferase
AL497_RS12745	COG1454	alcohol dehydrogenase
AL497_RS12745	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS12790	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS12795	COG3715	PTS system
AL497_RS12800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS12800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS12820	COG0531	amino acid
AL497_RS12830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS12840	COG1566	PFAM secretion protein HlyD family protein
AL497_RS12850	COG1473	amidohydrolase
AL497_RS12860	COG1924	4 iron, 4 sulfur cluster binding
AL497_RS12865	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AL497_RS12875	COG2733	membrane
AL497_RS12885	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS12890	COG0523	cobalamin synthesis protein
AL497_RS12895	COG2879	small protein
AL497_RS12900	COG1966	Carbon starvation protein
AL497_RS12905	COG2831	hemolysin activation secretion protein
AL497_RS12935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS12940	COG2368	4-hydroxyphenylacetate
AL497_RS12960	COG3971	2-oxopent-4-enoate hydratase activity
AL497_RS12970	COG3384	dioxygenase
AL497_RS12975	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS12985	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS12995	COG1846	Transcriptional regulator
AL497_RS13010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL497_RS13010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS13025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS13035	COG0531	amino acid
AL497_RS13050	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL497_RS13065	COG3734	2-keto-3-deoxy-galactonokinase
AL497_RS13070	COG0800	Aldolase
AL497_RS13075	COG1737	Transcriptional regulator
AL497_RS13075	COG0837	glucose binding
AL497_RS13100	COG1484	DNA-dependent DNA replication
AL497_RS13115	COG2966	Psort location CytoplasmicMembrane, score
AL497_RS13130	COG2197	response regulator
AL497_RS13135	COG2197	response regulator
AL497_RS13140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS13145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS13150	COG4114	ferric iron reductase
AL497_RS13155	COG3706	GGDEF domain
AL497_RS13185	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL497_RS13190	COG0456	acetyltransferase
AL497_RS13195	COG1011	Hydrolase
AL497_RS13205	COG2823	Periplasmic or secreted lipoprotein
AL497_RS13210	COG4667	esterase of the alpha-beta hydrolase superfamily
AL497_RS13215	COG0084	hydrolase, TatD family'
AL497_RS13245	COG3726	membrane protein affecting hemolysin expression
AL497_RS13250	COG0560	Phosphoserine phosphatase
AL497_RS13255	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL497_RS13265	COG0488	(ABC) transporter
AL497_RS13270	COG0741	lytic transglycosylase activity
AL497_RS13290	COG2207	Transcriptional regulator
AL497_RS13290	COG3708	Transcriptional regulator
AL497_RS13295	COG3045	CreA protein
AL497_RS13305	COG2205	protein histidine kinase activity
AL497_RS13310	COG4452	Inner membrane protein CreD
AL497_RS13315	COG0745	RESPONSE REGULATOR receiver
AL497_RS13320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL497_RS13325	COG0527	aspartate kinase activity
AL497_RS13325	COG0460	homoserine dehydrogenase
AL497_RS13335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL497_RS13345	COG1115	amino acid carrier protein
AL497_RS13350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL497_RS13355	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL497_RS13365	COG1584	GPR1 FUN34 yaaH family protein
AL497_RS13385	COG0583	DNA-binding transcription factor activity
AL497_RS13420	COG3539	Fimbrial protein
AL497_RS13430	COG3188	usher protein
AL497_RS13445	COG3539	Fimbrial protein
AL497_RS13450	COG3121	Chaperone
AL497_RS13470	COG0583	DNA-binding transcription factor activity
AL497_RS13480	COG0196	riboflavin kinase activity
AL497_RS13490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL497_RS13495	COG1047	Peptidyl-prolyl cis-trans
AL497_RS13510	COG0583	DNA-binding transcription factor activity
AL497_RS13515	COG2828	Protein conserved in bacteria
AL497_RS13520	COG0471	metal ion transport
AL497_RS13525	COG0471	metal ion transport
AL497_RS13530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL497_RS13540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL497_RS13605	COG0505	Belongs to the CarA family
AL497_RS13660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL497_RS13670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL497_RS13675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL497_RS13690	COG3493	citrate carrier protein
AL497_RS13700	COG0564	pseudouridine synthase activity
AL497_RS13710	COG0417	DNA replication proofreading
AL497_RS13715	COG0235	Class ii aldolase
AL497_RS13735	COG0586	Pfam SNARE associated Golgi protein
AL497_RS13745	COG1178	ABC-type Fe3 transport system permease component
AL497_RS13760	COG2814	Major facilitator Superfamily
AL497_RS13765	COG2271	Major facilitator Superfamily
AL497_RS13770	COG0583	DNA-binding transcription factor activity
AL497_RS13780	COG0738	Major facilitator superfamily
AL497_RS13820	COG0028	Belongs to the TPP enzyme family
AL497_RS13850	COG0768	penicillin binding
AL497_RS13855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL497_RS13860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL497_RS13875	COG0772	Belongs to the SEDS family
AL497_RS13890	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL497_RS13900	COG0849	cell division
AL497_RS13905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL497_RS13925	COG0494	nUDIX hydrolase
AL497_RS13950	COG1459	type II secretion system
AL497_RS13955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL497_RS13960	COG4969	Belongs to the N-Me-Phe pilin family
AL497_RS13975	COG3725	Membrane protein required for beta-lactamase induction
AL497_RS13980	COG3940	Belongs to the glycosyl hydrolase 43 family
AL497_RS13985	COG2211	Major facilitator Superfamily
AL497_RS13990	COG1113	amino acid transport
AL497_RS13995	COG2186	Transcriptional regulator
AL497_RS14000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL497_RS14005	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL497_RS14010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL497_RS14025	COG3064	Membrane
AL497_RS14030	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL497_RS14050	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS14065	COG2132	Multicopper oxidase
AL497_RS14070	COG4993	Dehydrogenase
AL497_RS14080	COG0288	reversible hydration of carbon dioxide
AL497_RS14085	COG1131	(ABC) transporter
AL497_RS14090	COG0842	Transport permease protein
AL497_RS14095	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS14100	COG0726	polysaccharide deacetylase
AL497_RS14105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL497_RS14120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL497_RS14145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL497_RS14150	COG1643	Atp-dependent helicase
AL497_RS14155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL497_RS14160	COG4774	siderophore transport
AL497_RS14165	COG1120	ATPase activity
AL497_RS14170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS14175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS14195	COG2860	membrane
AL497_RS14200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS14220	COG3835	regulator
AL497_RS14240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL497_RS14245	COG0024	Methionine aminopeptidase
AL497_RS14270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL497_RS14280	COG0575	Belongs to the CDS family
AL497_RS14285	COG0750	zinc metalloprotease
AL497_RS14340	COG1982	Orn Lys Arg decarboxylase major
AL497_RS14345	COG0346	lactoylglutathione lyase activity
AL497_RS14350	COG0037	tRNA processing
AL497_RS14355	COG4568	rho-dependent transcription termination
AL497_RS14370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL497_RS14375	COG3015	lipoprotein NlpE involved in copper resistance
AL497_RS14385	COG1720	tRNA m6t6A37 methyltransferase activity
AL497_RS14395	COG1464	Belongs to the NlpA lipoprotein family
AL497_RS14400	COG2011	ABC-type metal ion transport system permease component
AL497_RS14410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL497_RS14445	COG0656	L-ascorbic acid biosynthetic process
AL497_RS14450	COG0583	DNA-binding transcription factor activity
AL497_RS14455	COG2814	Major facilitator Superfamily
AL497_RS14465	COG2226	methyltransferase
AL497_RS14470	COG0741	lytic transglycosylase activity
AL497_RS14470	COG1388	LysM domain
AL497_RS14480	COG2226	methyltransferase
AL497_RS14490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS14500	COG0583	DNA-binding transcription factor activity
AL497_RS14510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL497_RS14515	COG1960	acyl-CoA dehydrogenase activity
AL497_RS14525	COG0121	glutamine amidotransferase
AL497_RS14530	COG3034	peptidoglycan biosynthetic process
AL497_RS14545	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL497_RS14550	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL497_RS14565	COG2991	Protein conserved in bacteria
AL497_RS14585	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL497_RS14605	COG1045	serine acetyltransferase
AL497_RS14620	COG0297	glycogen (starch) synthase activity
AL497_RS14620	COG0438	transferase activity, transferring glycosyl groups
AL497_RS14625	COG0438	transferase activity, transferring glycosyl groups
AL497_RS14630	COG0463	Glycosyl transferase, family 2
AL497_RS14650	COG1596	polysaccharide export
AL497_RS14660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL497_RS14675	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS14685	COG0583	DNA-binding transcription factor activity
AL497_RS14695	COG1802	Transcriptional regulator
AL497_RS14700	COG1113	amino acid transport
AL497_RS14705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS14710	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS14715	COG0579	oxidoreductase
AL497_RS14735	COG3188	usher protein
AL497_RS14740	COG3121	Chaperone
AL497_RS14790	COG0791	NLP P60 protein
AL497_RS14810	COG3639	organic phosphonate transmembrane transporter activity
AL497_RS14820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL497_RS14845	COG3188	usher protein
AL497_RS14865	COG2271	Major facilitator Superfamily
AL497_RS14870	COG0583	DNA-binding transcription factor activity
AL497_RS14875	COG0765	amino acid transport
AL497_RS14880	COG0765	amino acid transport
AL497_RS14890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS14895	COG0833	amino acid
AL497_RS14900	COG2040	homocysteine
AL497_RS14905	COG4521	taurine ABC transporter
AL497_RS14910	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL497_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS14920	COG2175	clavaminate synthase activity
AL497_RS14930	COG0113	porphobilinogen synthase activity
AL497_RS14935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL497_RS14945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AL497_RS14980	COG1785	Belongs to the alkaline phosphatase family
AL497_RS14990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL497_RS15000	COG3416	Protein conserved in bacteria
AL497_RS15005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL497_RS15015	COG4126	flavin adenine dinucleotide binding
AL497_RS15030	COG1940	carbohydrate kinase activity
AL497_RS15035	COG0419	ATPase involved in DNA repair
AL497_RS15040	COG0420	3'-5' exonuclease activity
AL497_RS15065	COG0366	Alpha amylase catalytic
AL497_RS15070	COG0583	DNA-binding transcription factor activity
AL497_RS15075	COG1335	isochorismatase
AL497_RS15085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL497_RS15090	COG0450	alkyl hydroperoxide reductase
AL497_RS15110	COG1862	Preprotein translocase
AL497_RS15120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL497_RS15135	COG3248	Nucleoside-binding outer membrane protein
AL497_RS15140	COG4238	major outer membrane lipoprotein
AL497_RS15150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL497_RS15150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL497_RS15170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL497_RS15175	COG0667	Aldo Keto reductase
AL497_RS15185	COG0142	geranyltranstransferase activity
AL497_RS15210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL497_RS15225	COG2831	hemolysin activation secretion protein
AL497_RS15235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL497_RS15240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS15250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS15265	COG1136	(ABC) transporter
AL497_RS15275	COG2177	Part of the ABC transporter FtsEX involved in
AL497_RS15305	COG2814	Major facilitator Superfamily
AL497_RS15320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL497_RS15325	COG1845	cytochrome c oxidase, subunit III
AL497_RS15330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL497_RS15335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL497_RS15340	COG2223	nitrite transmembrane transporter activity
AL497_RS15345	COG3056	Lipoprotein
AL497_RS15350	COG0271	Belongs to the BolA IbaG family
AL497_RS15370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL497_RS15375	COG0776	regulation of translation
AL497_RS15380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS15385	COG1555	photosystem II stabilization
AL497_RS15390	COG0824	Thioesterase
AL497_RS15400	COG4533	DNA binding
AL497_RS15415	COG1522	sequence-specific DNA binding
AL497_RS15420	COG1132	(ABC) transporter
AL497_RS15425	COG1132	(ABC) transporter
AL497_RS15430	COG0347	Belongs to the P(II) protein family
AL497_RS15435	COG0004	ammonium transporteR
AL497_RS15440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS15445	COG0583	DNA-binding transcription factor activity
AL497_RS15450	COG1946	Acyl-CoA thioesterase
AL497_RS15455	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL497_RS15460	COG3695	enzyme binding
AL497_RS15490	COG2364	Membrane
AL497_RS15495	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL497_RS15500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL497_RS15510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL497_RS15530	COG0110	maltose O-acetyltransferase activity
AL497_RS15545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS15550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS15555	COG1309	transcriptional regulator
AL497_RS15560	COG3264	Mechanosensitive ion channel
AL497_RS15560	COG1196	nuclear chromosome segregation
AL497_RS15565	COG3923	Primosomal replication protein n
AL497_RS15570	COG2832	Protein of unknown function (DUF454)
AL497_RS15610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS15615	COG4651	solute:proton antiporter activity
AL497_RS15615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL497_RS15620	COG2223	nitrite transmembrane transporter activity
AL497_RS15630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS15635	COG3735	TraB family
AL497_RS15650	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL497_RS15655	COG0330	HflC and HflK could
AL497_RS15660	COG4619	ABC transporter
AL497_RS15665	COG0390	transport system, permease component
AL497_RS15670	COG3118	belongs to the thioredoxin family
AL497_RS15675	COG0300	oxidoreductase activity
AL497_RS15680	COG2755	lipolytic protein G-D-S-L family
AL497_RS15685	COG4181	ATPase activity
AL497_RS15690	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL497_RS15705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL497_RS15710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL497_RS15720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL497_RS15730	COG2501	S4 domain
AL497_RS15770	COG0583	DNA-binding transcription factor activity
AL497_RS15785	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS15795	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS15800	COG3710	Transcriptional regulator
AL497_RS15805	COG0531	amino acid
AL497_RS15810	COG1982	Orn Lys Arg decarboxylase major
AL497_RS15815	COG3104	oligopeptide transport
AL497_RS15825	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS15830	COG0549	Belongs to the carbamate kinase family
AL497_RS15835	COG1304	FMN binding
AL497_RS15840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS15850	COG0666	response to abiotic stimulus
AL497_RS15860	COG0583	DNA-binding transcription factor activity
AL497_RS15875	COG1566	PFAM secretion protein HlyD family protein
AL497_RS15895	COG1473	amidohydrolase
AL497_RS15900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS15905	COG0667	Aldo Keto reductase
AL497_RS15955	COG0531	amino acid
AL497_RS15965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS15970	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS15975	COG1252	NADH dehydrogenase
AL497_RS15990	COG1113	amino acid transport
AL497_RS15995	COG0668	transmembrane transport
AL497_RS16000	COG0477	Major facilitator Superfamily
AL497_RS16015	COG0778	Nitroreductase
AL497_RS16020	COG2315	Protein conserved in bacteria
AL497_RS16050	COG3698	Phosphodiester glycosidase
AL497_RS16080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL497_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS16110	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS16115	COG1129	ABC transporter
AL497_RS16125	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS16130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL497_RS16135	COG2390	Transcriptional regulator
AL497_RS16140	COG3959	Transketolase, thiamine diphosphate binding domain
AL497_RS16145	COG3958	Transketolase
AL497_RS16150	COG4771	TonB-dependent receptor
AL497_RS16155	COG2382	esterase
AL497_RS16160	COG3251	PFAM MbtH domain protein
AL497_RS16165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS16165	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL497_RS16170	COG1120	ATPase activity
AL497_RS16175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS16180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS16185	COG0477	Major facilitator Superfamily
AL497_RS16195	COG4592	Periplasmic binding protein
AL497_RS16200	COG1169	isochorismate synthase
AL497_RS16205	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL497_RS16210	COG3433	isochorismatase activity
AL497_RS16210	COG1535	isochorismatase
AL497_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS16225	COG1966	Carbon starvation protein
AL497_RS16230	COG2879	small protein
AL497_RS16250	COG1129	ABC transporter
AL497_RS16255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS16280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL497_RS16290	COG0436	Aminotransferase
AL497_RS16295	COG1475	DNA binding
AL497_RS16300	COG3969	phosphoadenosine phosphosulfate
AL497_RS16305	COG0583	DNA-binding transcription factor activity
AL497_RS16310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL497_RS16320	COG3634	alkyl hydroperoxide reductase activity
AL497_RS16330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL497_RS16335	COG3719	Belongs to the RNase T2 family
AL497_RS16340	COG3069	C4-dicarboxylate transmembrane transporter activity
AL497_RS16360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL497_RS16375	COG0583	DNA-binding transcription factor activity
AL497_RS16390	COG1686	Belongs to the peptidase S11 family
AL497_RS16395	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL497_RS16400	COG0772	Belongs to the SEDS family
AL497_RS16405	COG0768	penicillin binding
AL497_RS16415	COG0799	negative regulation of ribosome biogenesis
AL497_RS16420	COG0406	alpha-ribazole phosphatase activity
AL497_RS16430	COG1466	dna polymerase III delta subunit
AL497_RS16445	COG2888	peptidyl-tyrosine sulfation
AL497_RS16455	COG2831	hemolysin activation secretion protein
AL497_RS16460	COG1126	abc transporter atp-binding protein
AL497_RS16465	COG0765	amino acid transport
AL497_RS16470	COG0765	amino acid transport
AL497_RS16495	COG1702	phosphate starvation-inducible protein PhoH
AL497_RS16505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS16545	COG0367	asparagine synthase
AL497_RS16550	COG0647	UMP catabolic process
AL497_RS16555	COG1846	Transcriptional regulator
AL497_RS16555	COG1940	carbohydrate kinase activity
AL497_RS16560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL497_RS16600	COG1053	succinate dehydrogenase
AL497_RS16605	COG0583	DNA-binding transcription factor activity
AL497_RS16610	COG0735	belongs to the Fur family
AL497_RS16625	COG0596	Alpha beta hydrolase
AL497_RS16635	COG0033	Phosphoglucomutase
AL497_RS16640	COG0745	RESPONSE REGULATOR receiver
AL497_RS16645	COG2205	protein histidine kinase activity
AL497_RS16675	COG0415	Belongs to the DNA photolyase family
AL497_RS16685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL497_RS16690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL497_RS16695	COG1984	allophanate hydrolase subunit 2
AL497_RS16725	COG0372	Belongs to the citrate synthase family
AL497_RS16730	COG2009	succinate dehydrogenase
AL497_RS16735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL497_RS16740	COG1053	succinate dehydrogenase
AL497_RS16745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL497_RS16750	COG0567	Dehydrogenase, E1 component
AL497_RS16755	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL497_RS16765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS16770	COG1271	oxidase subunit
AL497_RS16775	COG1294	oxidase, subunit
AL497_RS16780	COG4890	Cyd operon protein YbgT
AL497_RS16785	COG3790	cyd operon protein YbgE
AL497_RS16790	COG0824	Thioesterase
AL497_RS16795	COG0811	peptide transport
AL497_RS16800	COG0848	biopolymer transport protein
AL497_RS16805	COG3064	Membrane
AL497_RS16815	COG2885	chlorophyll binding
AL497_RS16820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL497_RS16875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL497_RS16885	COG1230	cation diffusion facilitator family transporter
AL497_RS16895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS16905	COG2017	converts alpha-aldose to the beta-anomer
AL497_RS16915	COG1085	galactose-1-phosphate uridylyltransferase
AL497_RS16920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL497_RS16925	COG1119	ATPase activity
AL497_RS16930	COG2005	Transcriptional regulator
AL497_RS16930	COG3585	molybdate ion transport
AL497_RS16935	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL497_RS16940	COG4149	molybdate abc transporter
AL497_RS16950	COG0561	phosphatase activity
AL497_RS16975	COG2200	EAL domain
AL497_RS16980	COG0789	Transcriptional regulator
AL497_RS17005	COG1595	DNA-templated transcription, initiation
AL497_RS17015	COG4677	pectinesterase activity
AL497_RS17050	COG1881	PFAM PEBP family protein
AL497_RS17055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL497_RS17070	COG2226	methyltransferase
AL497_RS17090	COG0745	RESPONSE REGULATOR receiver
AL497_RS17110	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL497_RS17120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL497_RS17125	COG0314	molybdopterin synthase activity
AL497_RS17130	COG0670	Belongs to the BI1 family
AL497_RS17135	COG0392	lysyltransferase activity
AL497_RS17140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL497_RS17145	COG3568	Endonuclease Exonuclease Phosphatase
AL497_RS17155	COG0842	Transport permease protein
AL497_RS17160	COG0842	Transport permease protein
AL497_RS17165	COG1131	(ABC) transporter
AL497_RS17175	COG1309	transcriptional regulator
AL497_RS17180	COG0513	Belongs to the DEAD box helicase family
AL497_RS17190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL497_RS17200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL497_RS17210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS17220	COG0668	transmembrane transport
AL497_RS17225	COG1126	abc transporter atp-binding protein
AL497_RS17230	COG0765	amino acid transport
AL497_RS17235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS17250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL497_RS17255	COG2194	sulfuric ester hydrolase activity
AL497_RS17265	COG1321	iron dependent repressor
AL497_RS17270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL497_RS17275	COG0667	Aldo Keto reductase
AL497_RS17280	COG2723	6-phospho-beta-galactosidase activity
AL497_RS17285	COG2188	Transcriptional regulator
AL497_RS17290	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS17300	COG0488	(ABC) transporter
AL497_RS17310	COG2271	Major facilitator Superfamily
AL497_RS17315	COG1609	Transcriptional regulator
AL497_RS17325	COG0561	phosphatase activity
AL497_RS17330	COG1882	Formate acetyltransferase
AL497_RS17335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS17340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL497_RS17345	COG0303	'Molybdopterin
AL497_RS17350	COG1446	asparaginase
AL497_RS17360	COG0747	negative chemotaxis
AL497_RS17385	COG2133	pyrroloquinoline quinone binding
AL497_RS17390	COG0625	glutathione transferase activity
AL497_RS17395	COG1686	Belongs to the peptidase S11 family
AL497_RS17400	COG1349	DNA-binding transcription factor activity
AL497_RS17405	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS17410	COG2814	Major facilitator Superfamily
AL497_RS17415	COG0561	phosphatase activity
AL497_RS17420	COG0738	Major facilitator superfamily
AL497_RS17425	COG3226	Transcriptional regulator
AL497_RS17430	COG0300	oxidoreductase activity
AL497_RS17470	COG0778	Nitroreductase
AL497_RS17485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL497_RS17490	COG3842	ATPase activity
AL497_RS17495	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL497_RS17500	COG1177	transmembrane transport
AL497_RS17510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL497_RS17515	COG0745	RESPONSE REGULATOR receiver
AL497_RS17520	COG5002	protein histidine kinase activity
AL497_RS17525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS17530	COG4160	amino acid transport
AL497_RS17535	COG4215	(ABC) transporter
AL497_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS17545	COG1126	abc transporter atp-binding protein
AL497_RS17555	COG2067	long-chain fatty acid transport protein
AL497_RS17565	COG5001	Diguanylate cyclase
AL497_RS17565	COG4251	negative regulation of phosphorylation
AL497_RS17565	COG3706	GGDEF domain
AL497_RS17565	COG2203	Gaf domain
AL497_RS17570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL497_RS17580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS17585	COG0702	epimerase
AL497_RS17590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL497_RS17595	COG0028	Belongs to the TPP enzyme family
AL497_RS17605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS17615	COG2431	L-lysine efflux transmembrane transporter activity
AL497_RS17625	COG3593	DNA synthesis involved in DNA repair
AL497_RS17630	COG2990	Protein conserved in bacteria
AL497_RS17635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS17645	COG1278	Cold shock
AL497_RS17655	COG0542	response to heat
AL497_RS17670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL497_RS17675	COG4988	ABC transporter
AL497_RS17680	COG0492	ferredoxin-NADP+ reductase activity
AL497_RS17700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL497_RS17715	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS17720	COG3302	dmso reductase anchor subunit
AL497_RS17725	COG0477	Major facilitator Superfamily
AL497_RS17730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS17735	COG1882	Formate acetyltransferase
AL497_RS17740	COG2116	formate transmembrane transporter activity
AL497_RS17745	COG1944	ATP diphosphatase activity
AL497_RS17770	COG0539	negative regulation of cytoplasmic translation
AL497_RS17780	COG2333	competence protein COMEC
AL497_RS17780	COG0658	competence protein
AL497_RS17795	COG3214	Protein conserved in bacteria
AL497_RS17800	COG2835	tetraacyldisaccharide 4'-kinase activity
AL497_RS17810	COG3173	Aminoglycoside phosphotransferase
AL497_RS17815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL497_RS17820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL497_RS17830	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL497_RS17840	COG2989	Protein conserved in bacteria
AL497_RS17845	COG3108	Peptidase M15
AL497_RS17850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL497_RS17855	COG1448	Aminotransferase
AL497_RS17860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS17870	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL497_RS17875	COG0308	aminopeptidase N
AL497_RS17885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS17890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS17895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS17900	COG0431	NADPH-dependent FMN reductase
AL497_RS17915	COG0633	Ferredoxin
AL497_RS17915	COG3217	Mosc domain protein beta barrel domain protein
AL497_RS17925	COG0488	(ABC) transporter
AL497_RS17930	COG2995	paraquat-inducible protein a
AL497_RS17935	COG3008	intermembrane lipid transfer
AL497_RS17935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL497_RS17940	COG3009	Protein conserved in bacteria
AL497_RS17950	COG1067	ATP-dependent peptidase activity
AL497_RS17970	COG3070	regulator of competence-specific genes
AL497_RS17975	COG1289	transmembrane transporter activity
AL497_RS17980	COG3304	Inner membrane component domain
AL497_RS17985	COG0210	DNA helicase
AL497_RS17995	COG1832	CoA-binding protein
AL497_RS18010	COG2274	protein secretion by the type I secretion system
AL497_RS18015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS18020	COG0438	transferase activity, transferring glycosyl groups
AL497_RS18050	COG0670	Belongs to the BI1 family
AL497_RS18065	COG0583	DNA-binding transcription factor activity
AL497_RS18080	COG0583	DNA-binding transcription factor activity
AL497_RS18130	COG1360	Flagellar Motor Protein
AL497_RS18135	COG2198	Histidine kinase
AL497_RS18135	COG0643	Histidine kinase
AL497_RS18140	COG0835	chemotaxis
AL497_RS18145	COG0840	transmembrane signaling receptor activity
AL497_RS18150	COG0840	transmembrane signaling receptor activity
AL497_RS18155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL497_RS18165	COG0745	RESPONSE REGULATOR receiver
AL497_RS18170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL497_RS18175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL497_RS18180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL497_RS18190	COG3418	PFAM FlgN family protein
AL497_RS18195	COG2747	anti-sigma28 factor FlgM
AL497_RS18205	COG1815	bacterial-type flagellum-dependent cell motility
AL497_RS18210	COG1558	bacterial-type flagellum-dependent cell motility
AL497_RS18215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL497_RS18230	COG4786	Flagellar basal body rod
AL497_RS18250	COG1256	bacterial-type flagellum assembly
AL497_RS18285	COG2814	Major facilitator Superfamily
AL497_RS18295	COG1414	Transcriptional regulator
AL497_RS18300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL497_RS18305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL497_RS18370	COG2882	bacterial-type flagellum organization
AL497_RS18375	COG1157	protein secretion by the type III secretion system
AL497_RS18385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL497_RS18390	COG1766	The M ring may be actively involved in energy transduction
AL497_RS18395	COG1677	Flagellar hook-basal body complex protein FliE
AL497_RS18420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL497_RS18435	COG1191	sigma factor activity
AL497_RS18475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS18480	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS18485	COG4638	Rieske (2fe-2S)
AL497_RS18490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL497_RS18500	COG0473	3-isopropylmalate dehydrogenase activity
AL497_RS18505	COG0583	DNA-binding transcription factor activity
AL497_RS18510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS18515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS18525	COG1396	sequence-specific DNA binding
AL497_RS18525	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS18530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL497_RS18535	COG0174	glutamine synthetase
AL497_RS18540	COG0531	amino acid
AL497_RS18595	COG3729	General stress protein
AL497_RS18605	COG2233	PERMEase
AL497_RS18640	COG1309	transcriptional regulator
AL497_RS18655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL497_RS18660	COG0628	permease
AL497_RS18670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS18680	COG2822	iron ion transport
AL497_RS18690	COG1702	phosphate starvation-inducible protein PhoH
AL497_RS18700	COG1335	isochorismatase
AL497_RS18710	COG0583	DNA-binding transcription factor activity
AL497_RS18740	COG3381	protein complex oligomerization
AL497_RS18780	COG5645	(Lipo)protein
AL497_RS18795	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS18835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS18845	COG0673	inositol 2-dehydrogenase activity
AL497_RS18855	COG2814	Major facilitator Superfamily
AL497_RS18860	COG0583	DNA-binding transcription factor activity
AL497_RS18865	COG1530	ribonuclease E activity
AL497_RS18880	COG1399	metal-binding, possibly nucleic acid-binding protein
AL497_RS18900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL497_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS18915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS18920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL497_RS18925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL497_RS18935	COG0470	DNA polymerase III
AL497_RS18940	COG0084	hydrolase, TatD family'
AL497_RS18945	COG1263	PTS System
AL497_RS18945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS18950	COG0537	adenosine 5'-monophosphoramidase activity
AL497_RS18955	COG5633	Lipoprotein
AL497_RS18980	COG1252	NADH dehydrogenase
AL497_RS18985	COG3134	Outer membrane lipoprotein
AL497_RS18995	COG1309	transcriptional regulator
AL497_RS19005	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS19005	COG1388	LysM domain
AL497_RS19010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL497_RS19015	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL497_RS19020	COG1136	(ABC) transporter
AL497_RS19025	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL497_RS19035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL497_RS19040	COG2390	Transcriptional regulator
AL497_RS19055	COG3395	kinase activity
AL497_RS19070	COG0698	ribose 5-phosphate isomerase
AL497_RS19075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL497_RS19080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS19090	COG0318	PFAM AMP-dependent synthetase and ligase
AL497_RS19100	COG1177	transmembrane transport
AL497_RS19120	COG1943	Transposase
AL497_RS19125	COG2850	peptidyl-arginine hydroxylation
AL497_RS19140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL497_RS19160	COG1187	pseudouridine synthase activity
AL497_RS19165	COG0538	isocitrate dehydrogenase activity
AL497_RS19175	COG2963	transposase activity
AL497_RS19195	COG1403	HNH endonuclease
AL497_RS19200	COG3272	Protein of unknown function (DUF1722)
AL497_RS19205	COG0789	Transcriptional regulator
AL497_RS19215	COG4977	sequence-specific DNA binding
AL497_RS19220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS19245	COG3122	Protein conserved in bacteria
AL497_RS19255	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AL497_RS19260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS19265	COG3477	response to acidic pH
AL497_RS19270	COG0012	GTP binding
AL497_RS19285	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS19315	COG2890	protein-(glutamine-N5) methyltransferase activity
AL497_RS19335	COG0387	Pfam Sodium calcium exchanger
AL497_RS19340	COG4572	Cation transport regulator
AL497_RS19345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL497_RS19355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL497_RS19360	COG3707	response regulator
AL497_RS19365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS19375	COG1116	anion transmembrane transporter activity
AL497_RS19380	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS19380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL497_RS19385	COG0243	molybdopterin cofactor binding
AL497_RS19390	COG4932	domain protein
AL497_RS19395	COG2197	response regulator
AL497_RS19400	COG3850	Histidine kinase
AL497_RS19405	COG2223	nitrite transmembrane transporter activity
AL497_RS19410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL497_RS19415	COG1140	nitrate reductase beta subunit
AL497_RS19420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL497_RS19425	COG2181	nitrate reductase activity
AL497_RS19435	COG1522	sequence-specific DNA binding
AL497_RS19465	COG0788	formyltetrahydrofolate deformylase activity
AL497_RS19475	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL497_RS19480	COG0745	RESPONSE REGULATOR receiver
AL497_RS19485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL497_RS19500	COG1454	alcohol dehydrogenase
AL497_RS19500	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS19505	COG2095	MarC family integral membrane protein
AL497_RS19515	COG0601	transmembrane transport
AL497_RS19520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS19525	COG0444	Belongs to the ABC transporter superfamily
AL497_RS19535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL497_RS19550	COG2963	transposase activity
AL497_RS19560	COG0823	Involved in the tonB-independent uptake of proteins
AL497_RS19585	COG2963	transposase activity
AL497_RS19600	COG2135	peptidase activity
AL497_RS19605	COG2350	Protein conserved in bacteria
AL497_RS19610	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL497_RS19615	COG3001	Fructosamine kinase
AL497_RS19625	COG1105	Belongs to the carbohydrate kinase PfkB family
AL497_RS19630	COG3137	Salt-induced outer membrane protein
AL497_RS19650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL497_RS19660	COG0072	phenylalanine-tRNA ligase activity
AL497_RS19660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL497_RS19680	COG0583	DNA-binding transcription factor activity
AL497_RS19700	COG0386	Belongs to the glutathione peroxidase family
AL497_RS19710	COG0791	NLP P60 protein
AL497_RS19720	COG4256	Hemin uptake protein
AL497_RS19725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS19735	COG0574	Belongs to the PEP-utilizing enzyme family
AL497_RS19735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL497_RS19745	COG0628	permease
AL497_RS19750	COG0247	lactate metabolic process
AL497_RS19750	COG0277	FAD linked oxidase domain protein
AL497_RS19755	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS19760	COG3422	double-strand break repair
AL497_RS19765	COG2261	transglycosylase associated protein
AL497_RS19775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL497_RS19785	COG0316	Belongs to the HesB IscA family
AL497_RS19790	COG0719	Fe-S assembly protein
AL497_RS19795	COG0396	ATPase activity
AL497_RS19800	COG0719	Fe-S assembly protein
AL497_RS19815	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS19840	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AL497_RS19840	COG1082	Xylose isomerase domain protein TIM barrel
AL497_RS19845	COG2271	Major facilitator Superfamily
AL497_RS19850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL497_RS19860	COG1120	ATPase activity
AL497_RS19865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS19870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS19895	COG0583	DNA-binding transcription factor activity
AL497_RS19900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS19920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS19925	COG1116	anion transmembrane transporter activity
AL497_RS19935	COG1120	ATPase activity
AL497_RS19940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS19945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS19965	COG0765	amino acid transport
AL497_RS19970	COG1126	abc transporter atp-binding protein
AL497_RS19980	COG1473	amidohydrolase
AL497_RS19985	COG1683	Conserved Protein
AL497_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS19995	COG2378	regulation of single-species biofilm formation
AL497_RS20015	COG1280	lysine exporter protein (LysE YggA)
AL497_RS20035	COG3590	peptidase
AL497_RS20045	COG2207	Transcriptional regulator
AL497_RS20055	COG0251	oxidation-reduction process
AL497_RS20060	COG1309	transcriptional regulator
AL497_RS20085	COG1396	sequence-specific DNA binding
AL497_RS20090	COG0456	acetyltransferase
AL497_RS20105	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS20110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL497_RS20120	COG1175	transmembrane transport
AL497_RS20150	COG1138	Cytochrome C-type biogenesis protein
AL497_RS20180	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS20185	COG2610	gluconate transmembrane transporter activity
AL497_RS20190	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS20200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL497_RS20210	COG0583	DNA-binding transcription factor activity
AL497_RS20215	COG4993	Dehydrogenase
AL497_RS20225	COG4608	Belongs to the ABC transporter superfamily
AL497_RS20230	COG0444	Belongs to the ABC transporter superfamily
AL497_RS20255	COG0346	lactoylglutathione lyase activity
AL497_RS20260	COG1349	DNA-binding transcription factor activity
AL497_RS20275	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS20280	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS20285	COG2233	PERMEase
AL497_RS20290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS20290	COG0493	'glutamate synthase
AL497_RS20295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS20300	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS20305	COG0493	'glutamate synthase
AL497_RS20305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS20310	COG2068	MobA-Related Protein
AL497_RS20315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL497_RS20320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL497_RS20320	COG3608	succinylglutamate desuccinylase aspartoacylase
AL497_RS20325	COG0549	Belongs to the carbamate kinase family
AL497_RS20335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL497_RS20340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL497_RS20345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL497_RS20350	COG3829	transcription factor binding
AL497_RS20355	COG2223	nitrite transmembrane transporter activity
AL497_RS20415	COG0534	Mate efflux family protein
AL497_RS20420	COG0307	riboflavin synthase, alpha
AL497_RS20425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL497_RS20430	COG2814	Major facilitator Superfamily
AL497_RS20435	COG0583	DNA-binding transcription factor activity
AL497_RS20445	COG2814	Major facilitator Superfamily
AL497_RS20455	COG2207	Transcriptional regulator
AL497_RS20455	COG3708	Transcriptional regulator
AL497_RS20460	COG0791	NLP P60 protein
AL497_RS20465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL497_RS20475	COG0346	lactoylglutathione lyase activity
AL497_RS20480	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS20485	COG1309	transcriptional regulator
AL497_RS20490	COG3313	Fe-S protein
AL497_RS20495	COG4989	oxidoreductase activity
AL497_RS20500	COG2032	superoxide dismutase activity
AL497_RS20505	COG1289	transmembrane transporter activity
AL497_RS20510	COG1566	PFAM secretion protein HlyD family protein
AL497_RS20525	COG3706	GGDEF domain
AL497_RS20540	COG3895	Periplasmic Protein
AL497_RS20555	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL497_RS20560	COG0625	glutathione transferase activity
AL497_RS20570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL497_RS20580	COG4659	FMN binding
AL497_RS20615	COG2723	6-phospho-beta-galactosidase activity
AL497_RS20635	COG5562	phage envelope protein
AL497_RS20655	COG0425	Belongs to the sulfur carrier protein TusA family
AL497_RS20660	COG2391	methyltransferase activity
AL497_RS20670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL497_RS20675	COG1263	PTS System
AL497_RS20675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS20680	COG1609	Transcriptional regulator
AL497_RS20685	COG5339	Protein conserved in bacteria
AL497_RS20690	COG1482	cell wall glycoprotein biosynthetic process
AL497_RS20695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS20695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS20710	COG2205	protein histidine kinase activity
AL497_RS20720	COG0745	RESPONSE REGULATOR receiver
AL497_RS20725	COG3136	membrane protein required for alginate biosynthesis
AL497_RS20735	COG0531	amino acid
AL497_RS20745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL497_RS20750	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL497_RS20765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL497_RS20770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL497_RS20775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL497_RS20780	COG1473	amidohydrolase
AL497_RS20790	COG0583	DNA-binding transcription factor activity
AL497_RS20795	COG2840	Smr protein MutS2
AL497_RS20800	COG1414	Transcriptional regulator
AL497_RS20810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL497_RS20815	COG0183	Belongs to the thiolase family
AL497_RS20825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL497_RS20830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS20840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS20840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS20860	COG4565	transcriptional regulatory protein
AL497_RS20865	COG3290	protein histidine kinase activity
AL497_RS20870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL497_RS20885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL497_RS20895	COG0679	Auxin Efflux Carrier
AL497_RS20925	COG0628	permease
AL497_RS20940	COG3300	MHYT domain
AL497_RS20940	COG5001	Diguanylate cyclase
AL497_RS20945	COG3591	Belongs to the peptidase S1B family
AL497_RS20960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL497_RS20965	COG2814	Major facilitator Superfamily
AL497_RS20970	COG0583	DNA-binding transcription factor activity
AL497_RS20975	COG1940	carbohydrate kinase activity
AL497_RS20980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL497_RS20995	COG3302	dmso reductase anchor subunit
AL497_RS21000	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS21005	COG0243	molybdopterin cofactor binding
AL497_RS21020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS21035	COG2271	Major facilitator Superfamily
AL497_RS21040	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS21045	COG1063	alcohol dehydrogenase
AL497_RS21050	COG0477	Major facilitator Superfamily
AL497_RS21055	COG0246	Mannitol dehydrogenase
AL497_RS21065	COG1802	Transcriptional regulator
AL497_RS21070	COG4221	oxidoreductase activity
AL497_RS21075	COG0339	signal peptide processing
AL497_RS21085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL497_RS21090	COG2223	nitrite transmembrane transporter activity
AL497_RS21110	COG2203	Gaf domain
AL497_RS21110	COG2199	diguanylate cyclase activity
AL497_RS21130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL497_RS21140	COG2814	Major facilitator Superfamily
AL497_RS21145	COG0697	spore germination
AL497_RS21160	COG1846	Transcriptional regulator
AL497_RS21180	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS21200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS21210	COG3395	kinase activity
AL497_RS21215	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL497_RS21220	COG1349	DNA-binding transcription factor activity
AL497_RS21225	COG0583	DNA-binding transcription factor activity
AL497_RS21230	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS21245	COG2199	diguanylate cyclase activity
AL497_RS21265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS21270	COG2271	Major facilitator Superfamily
AL497_RS21275	COG3622	Belongs to the hyi family
AL497_RS21280	COG0235	Class ii aldolase
AL497_RS21285	COG3395	kinase activity
AL497_RS21290	COG1349	DNA-binding transcription factor activity
AL497_RS21315	COG0697	spore germination
AL497_RS21320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS21325	COG0477	Major facilitator Superfamily
AL497_RS21335	COG2070	2-Nitropropane dioxygenase
AL497_RS21340	COG2011	ABC-type metal ion transport system permease component
AL497_RS21360	COG4628	conserved protein (DUF2132)
AL497_RS21365	COG2207	Transcriptional regulator
AL497_RS21390	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS21395	COG3729	General stress protein
AL497_RS21400	COG3685	Protein conserved in bacteria
AL497_RS21415	COG1271	oxidase subunit
AL497_RS21420	COG1294	oxidase, subunit
AL497_RS21435	COG2323	membrane
AL497_RS21445	COG3111	PFAM Bacterial OB fold (BOF) protein
AL497_RS21450	COG0626	cystathionine gamma-synthase activity
AL497_RS21465	COG2610	gluconate transmembrane transporter activity
AL497_RS21470	COG1312	Catalyzes the dehydration of D-mannonate
AL497_RS21480	COG4529	Protein conserved in bacteria
AL497_RS21495	COG2814	Major facilitator Superfamily
AL497_RS21500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL497_RS21505	COG0588	phosphoglycerate mutase activity
AL497_RS21515	COG2723	6-phospho-beta-galactosidase activity
AL497_RS21525	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS21530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS21535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS21540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS21545	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS21550	COG1940	carbohydrate kinase activity
AL497_RS21555	COG1609	Transcriptional regulator
AL497_RS21565	COG0667	Aldo Keto reductase
AL497_RS21570	COG0667	Aldo Keto reductase
AL497_RS21575	COG0667	Aldo Keto reductase
AL497_RS21600	COG0656	L-ascorbic acid biosynthetic process
AL497_RS21610	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL497_RS21615	COG0667	Aldo Keto reductase
AL497_RS21720	COG2814	Major facilitator Superfamily
AL497_RS21730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL497_RS21740	COG0765	amino acid transport
AL497_RS21745	COG0765	amino acid transport
AL497_RS21795	COG1953	Uracil, thiamine, allantoin
AL497_RS21800	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS21805	COG2351	hydroxyisourate hydrolase activity
AL497_RS21815	COG2233	PERMEase
AL497_RS21820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS21850	COG0454	-acetyltransferase
AL497_RS21855	COG0668	transmembrane transport
AL497_RS21925	COG0515	serine threonine protein kinase
AL497_RS21925	COG2815	serine threonine protein kinase
AL497_RS22040	COG1649	PFAM Uncharacterised BCR, COG1649
AL497_RS22045	COG2070	2-Nitropropane dioxygenase
AL497_RS22050	COG0583	DNA-binding transcription factor activity
AL497_RS22085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL497_RS22090	COG1116	anion transmembrane transporter activity
AL497_RS22095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS22100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS22105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS22110	COG0076	glutamate decarboxylase activity
AL497_RS22120	COG2205	protein histidine kinase activity
AL497_RS22185	COG0583	DNA-binding transcription factor activity
AL497_RS22195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL497_RS22200	COG1309	transcriptional regulator
AL497_RS22220	COG2814	Major facilitator Superfamily
AL497_RS22230	COG0583	DNA-binding transcription factor activity
AL497_RS22235	COG0583	DNA-binding transcription factor activity
AL497_RS22240	COG0243	molybdopterin cofactor binding
AL497_RS22245	COG1271	oxidase subunit
AL497_RS22250	COG1294	oxidase, subunit
AL497_RS22255	COG3781	membrane
AL497_RS22260	COG2837	iron assimilation
AL497_RS22275	COG1764	response to oxidative stress
AL497_RS22300	COG1609	Transcriptional regulator
AL497_RS22320	COG0488	(ABC) transporter
AL497_RS22330	COG1064	alcohol dehydrogenase
AL497_RS22335	COG0747	negative chemotaxis
AL497_RS22345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS22355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS22365	COG2814	Major facilitator Superfamily
AL497_RS22420	COG2864	formate dehydrogenase
AL497_RS22425	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS22430	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS22430	COG0243	molybdopterin cofactor binding
AL497_RS22435	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS22435	COG0243	molybdopterin cofactor binding
AL497_RS22440	COG0697	spore germination
AL497_RS22455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL497_RS22465	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS22470	COG4829	muconolactone delta-isomerase
AL497_RS22475	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS22480	COG1414	Transcriptional regulator
AL497_RS22500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL497_RS22505	COG1140	nitrate reductase beta subunit
AL497_RS22510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL497_RS22515	COG2181	nitrate reductase activity
AL497_RS22520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL497_RS22525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS22545	COG0625	glutathione transferase activity
AL497_RS22550	COG3619	membrane
AL497_RS22555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS22560	COG1126	abc transporter atp-binding protein
AL497_RS22575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS22580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS22585	COG1473	amidohydrolase
AL497_RS22590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS22620	COG4772	TonB-dependent receptor
AL497_RS22625	COG3691	Protein conserved in bacteria
AL497_RS22630	COG2130	NADP-dependent
AL497_RS22640	COG1247	-acetyltransferase
AL497_RS22645	COG3238	Protein conserved in bacteria
AL497_RS22655	COG0747	negative chemotaxis
AL497_RS22660	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS22665	COG2267	carboxylic ester hydrolase activity
AL497_RS22670	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS22675	COG1177	transmembrane transport
AL497_RS22685	COG3842	ATPase activity
AL497_RS22690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL497_RS22695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS22700	COG1271	oxidase subunit
AL497_RS22705	COG1294	oxidase, subunit
AL497_RS22715	COG0826	peptidase U32
AL497_RS22720	COG1396	sequence-specific DNA binding
AL497_RS22725	COG3135	benzoate transporter
AL497_RS22730	COG3708	Transcriptional regulator
AL497_RS22730	COG2207	Transcriptional regulator
AL497_RS22735	COG0697	spore germination
AL497_RS22745	COG0747	negative chemotaxis
AL497_RS22750	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL497_RS22755	COG0500	methyltransferase
AL497_RS22760	COG1275	C4-dicarboxylate transporter malic acid transport protein
AL497_RS22765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS22770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS22790	COG0436	Aminotransferase
AL497_RS22795	COG1823	symporter activity
AL497_RS22800	COG1335	isochorismatase
AL497_RS22805	COG0583	DNA-binding transcription factor activity
AL497_RS22810	COG2272	Belongs to the type-B carboxylesterase lipase family
AL497_RS22815	COG5383	Protein conserved in bacteria
AL497_RS22820	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS22825	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS22830	COG0583	DNA-binding transcription factor activity
AL497_RS22870	COG3038	cytochrome b561
AL497_RS22895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL497_RS22900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL497_RS22905	COG1113	amino acid transport
AL497_RS22910	COG2988	succinylglutamate desuccinylase activity
AL497_RS22915	COG3724	N-succinylarginine dihydrolase activity
AL497_RS22920	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS22925	COG3138	arginine N-succinyltransferase
AL497_RS22930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL497_RS22935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL497_RS22960	COG4122	O-methyltransferase activity
AL497_RS22965	COG1643	Atp-dependent helicase
AL497_RS22980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS22985	COG3327	negative regulation of DNA-templated transcription, initiation
AL497_RS22990	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AL497_RS22995	COG0183	Belongs to the thiolase family
AL497_RS23000	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS23005	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS23010	COG1024	Enoyl-CoA hydratase
AL497_RS23015	COG1024	Enoyl-CoA hydratase
AL497_RS23020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS23025	COG2151	metal-sulfur cluster biosynthetic enzyme
AL497_RS23030	COG3396	Phenylacetate-CoA oxygenase
AL497_RS23035	COG3460	Phenylacetate-CoA oxygenase
AL497_RS23040	COG3396	Phenylacetate-CoA oxygenase
AL497_RS23045	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS23045	COG2030	dehydratase
AL497_RS23060	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS23065	COG2207	Transcriptional regulator
AL497_RS23070	COG3784	Protein of unknown function (DUF1318)
AL497_RS23080	COG2911	Protein conserved in bacteria
AL497_RS23085	COG0586	Pfam SNARE associated Golgi protein
AL497_RS23090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL497_RS23095	COG3187	Heat shock protein
AL497_RS23100	COG3042	response to heat
AL497_RS23105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS23105	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL497_RS23105	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL497_RS23105	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL497_RS23110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS23115	COG0589	response to stress
AL497_RS23125	COG0513	Belongs to the DEAD box helicase family
AL497_RS23135	COG1940	carbohydrate kinase activity
AL497_RS23140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS23165	COG4172	Belongs to the ABC transporter superfamily
AL497_RS23170	COG1349	DNA-binding transcription factor activity
AL497_RS23175	COG0673	inositol 2-dehydrogenase activity
AL497_RS23185	COG0693	protein deglycase activity
AL497_RS23225	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS23230	COG2211	Major facilitator Superfamily
AL497_RS23235	COG3507	Belongs to the glycosyl hydrolase 43 family
AL497_RS23240	COG0656	L-ascorbic acid biosynthetic process
AL497_RS23250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS23260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL497_RS23275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS23285	COG4166	transmembrane transport
AL497_RS23290	COG2866	Carboxypeptidase
AL497_RS23295	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS23300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL497_RS23305	COG3180	Ammonia monooxygenase
AL497_RS23320	COG3106	COG3106 Predicted ATPase
AL497_RS23330	COG1983	PspC domain protein
AL497_RS23340	COG1842	Phage shock protein A
AL497_RS23345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL497_RS23355	COG1473	amidohydrolase
AL497_RS23380	COG2135	peptidase activity
AL497_RS23385	COG2200	EAL domain
AL497_RS23390	COG0431	NADPH-dependent FMN reductase
AL497_RS23395	COG0640	Transcriptional regulator
AL497_RS23410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL497_RS23460	COG1196	nuclear chromosome segregation
AL497_RS23460	COG1196	nuclear chromosome segregation
AL497_RS23535	COG3728	DNA packaging
AL497_RS23535	COG5484	DNA packaging
AL497_RS23555	COG3728	DNA packaging
AL497_RS23555	COG5484	DNA packaging
AL497_RS23600	COG0484	heat shock protein binding
AL497_RS23625	COG0456	acetyltransferase
AL497_RS23665	COG1846	Transcriptional regulator
AL497_RS23715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS23740	COG4171	peptide transport system, permease
AL497_RS23750	COG4172	Belongs to the ABC transporter superfamily
AL497_RS23755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS23765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL497_RS23770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS23770	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS23785	COG1349	DNA-binding transcription factor activity
AL497_RS23795	COG0023	Translation Initiation Factor
AL497_RS23805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL497_RS23810	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL497_RS23815	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS23825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL497_RS23845	COG0616	signal peptide processing
AL497_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS23855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL497_RS23860	COG2207	Transcriptional regulator
AL497_RS23865	COG1472	Belongs to the glycosyl hydrolase 3 family
AL497_RS23870	COG2211	Major facilitator Superfamily
AL497_RS23880	COG1716	ATPase activity
AL497_RS23880	COG5001	Diguanylate cyclase
AL497_RS23885	COG5001	Diguanylate cyclase
AL497_RS23885	COG1716	ATPase activity
AL497_RS23890	COG0009	L-threonylcarbamoyladenylate synthase
AL497_RS23900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL497_RS23905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL497_RS23905	COG0512	Glutamine amidotransferase of anthranilate synthase
AL497_RS23910	COG0135	phosphoribosylanthranilate isomerase activity
AL497_RS23910	COG0134	indole-3-glycerol-phosphate synthase activity
AL497_RS23935	COG1566	PFAM secretion protein HlyD family protein
AL497_RS23950	COG0583	DNA-binding transcription factor activity
AL497_RS23955	COG3047	cAMP biosynthetic process
AL497_RS23960	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL497_RS23985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS23990	COG1988	membrane-bound metal-dependent
AL497_RS23995	COG1823	symporter activity
AL497_RS24005	COG0753	catalase activity
AL497_RS24015	COG1486	melibiose metabolic process
AL497_RS24020	COG2169	Transcriptional regulator
AL497_RS24020	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS24025	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS24030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS24035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS24040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL497_RS24050	COG0322	excinuclease ABC activity
AL497_RS24055	COG3678	ATP-independent chaperone mediated protein folding
AL497_RS24070	COG3138	arginine N-succinyltransferase
AL497_RS24080	COG0708	Exodeoxyribonuclease III
AL497_RS24085	COG0398	Pfam SNARE associated Golgi protein
AL497_RS24090	COG0398	Pfam SNARE associated Golgi protein
AL497_RS24095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS24100	COG4134	Bacterial extracellular solute-binding protein
AL497_RS24105	COG4135	transport system, permease component
AL497_RS24110	COG4136	ATPase activity
AL497_RS24115	COG2897	thiosulfate sulfurtransferase activity
AL497_RS24120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL497_RS24125	COG0494	nUDIX hydrolase
AL497_RS24135	COG3321	synthase
AL497_RS24135	COG0604	alcohol dehydrogenase
AL497_RS24135	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS24145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL497_RS24150	COG0709	Synthesizes selenophosphate from selenide and ATP
AL497_RS24160	COG0778	Nitroreductase
AL497_RS24165	COG0616	signal peptide processing
AL497_RS24170	COG0252	asparaginase activity
AL497_RS24175	COG1335	isochorismatase
AL497_RS24185	COG3139	Protein of unknown function (DUF1315)
AL497_RS24205	COG3713	MltA-interacting MipA family protein
AL497_RS24210	COG2766	serine protein kinase
AL497_RS24220	COG2199	diguanylate cyclase activity
AL497_RS24225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS24235	COG2207	Transcriptional regulator
AL497_RS24240	COG2807	transmembrane transport
AL497_RS24245	COG0504	CTP synthase activity
AL497_RS24250	COG3189	MarR family transcriptional regulator
AL497_RS24255	COG3042	response to heat
AL497_RS24260	COG2203	Gaf domain
AL497_RS24260	COG2199	diguanylate cyclase activity
AL497_RS24265	COG3182	Iron-regulated membrane protein
AL497_RS24275	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS24280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL497_RS24285	COG3706	GGDEF domain
AL497_RS24310	COG3209	COG3209 Rhs family protein
AL497_RS24325	COG3209	COG3209 Rhs family protein
AL497_RS24345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL497_RS24440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS24450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL497_RS24470	COG1760	l-serine dehydratase
AL497_RS24475	COG1882	Formate acetyltransferase
AL497_RS24495	COG0583	DNA-binding transcription factor activity
AL497_RS24500	COG2814	Major facilitator Superfamily
AL497_RS24515	COG4774	siderophore transport
AL497_RS24525	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL497_RS24545	COG2719	SpoVR family
AL497_RS24575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL497_RS24575	COG2755	lipolytic protein G-D-S-L family
AL497_RS24585	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS24600	COG2894	cell division
AL497_RS24610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides