locus-tag	class	description
LI64_RS00010	COG0592	DNA-directed DNA polymerase activity
LI64_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LI64_RS00025	COG2186	Transcriptional regulator
LI64_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS00035	COG0246	Mannitol dehydrogenase
LI64_RS00040	COG1063	alcohol dehydrogenase
LI64_RS00045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LI64_RS00050	COG2271	Major facilitator Superfamily
LI64_RS00055	COG0561	phosphatase activity
LI64_RS00060	COG2186	Transcriptional regulator
LI64_RS00065	COG3734	2-keto-3-deoxy-galactonokinase
LI64_RS00070	COG0800	Aldolase
LI64_RS00075	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS00080	COG2271	Major facilitator Superfamily
LI64_RS00085	COG0823	Involved in the tonB-independent uptake of proteins
LI64_RS00090	COG5645	(Lipo)protein
LI64_RS00100	COG0071	Belongs to the small heat shock protein (HSP20) family
LI64_RS00105	COG2985	domain, Protein
LI64_RS00130	COG2188	Transcriptional regulator
LI64_RS00145	COG2149	membrane
LI64_RS00155	COG0641	radical SAM
LI64_RS00175	COG2814	Major facilitator Superfamily
LI64_RS00195	COG5499	transcription regulator containing HTH domain
LI64_RS00200	COG0028	Belongs to the TPP enzyme family
LI64_RS00205	COG0440	acetolactate synthase activity
LI64_RS00210	COG2197	response regulator
LI64_RS00220	COG2271	Major facilitator Superfamily
LI64_RS00230	COG0596	Alpha beta hydrolase
LI64_RS00240	COG0583	DNA-binding transcription factor activity
LI64_RS00260	COG2814	Major facilitator Superfamily
LI64_RS00265	COG0183	Belongs to the thiolase family
LI64_RS00270	COG0667	Aldo Keto reductase
LI64_RS00280	COG0697	spore germination
LI64_RS00285	COG4580	involved in the transport of maltose and maltodextrins
LI64_RS00290	COG1447	Phosphotransferase system cellobiose-specific component IIA
LI64_RS00295	COG2723	6-phospho-beta-galactosidase activity
LI64_RS00300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS00300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS00310	COG1609	Transcriptional regulator
LI64_RS00320	COG0454	-acetyltransferase
LI64_RS00325	COG1309	transcriptional regulator
LI64_RS00340	COG1487	ribonuclease activity
LI64_RS00350	COG1464	Belongs to the NlpA lipoprotein family
LI64_RS00380	COG3121	Chaperone
LI64_RS00410	COG3188	usher protein
LI64_RS00435	COG2274	protein secretion by the type I secretion system
LI64_RS00450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LI64_RS00465	COG3272	Protein of unknown function (DUF1722)
LI64_RS00470	COG2351	hydroxyisourate hydrolase activity
LI64_RS00475	COG0789	Transcriptional regulator
LI64_RS00500	COG3121	Chaperone
LI64_RS00525	COG0431	NADPH-dependent FMN reductase
LI64_RS00555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LI64_RS00580	COG0210	DNA helicase
LI64_RS00585	COG0582	viral genome integration into host DNA
LI64_RS00595	COG2211	Major facilitator Superfamily
LI64_RS00600	COG1501	Belongs to the glycosyl hydrolase 31 family
LI64_RS00605	COG2982	Protein involved in outer membrane biogenesis
LI64_RS00615	COG0786	glutamate:sodium symporter activity
LI64_RS00620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LI64_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI64_RS00630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LI64_RS00645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LI64_RS00665	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS00670	COG1596	polysaccharide export
LI64_RS00675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LI64_RS00680	COG3206	protein involved in exopolysaccharide biosynthesis
LI64_RS00680	COG0489	protein tyrosine kinase activity
LI64_RS00685	COG2860	membrane
LI64_RS00690	COG1561	YicC-like family, N-terminal region
LI64_RS00700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LI64_RS00710	COG0756	dUTP diphosphatase activity
LI64_RS00715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LI64_RS00720	COG2003	Belongs to the UPF0758 family
LI64_RS00725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LI64_RS00730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LI64_RS00735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LI64_RS00740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LI64_RS00750	COG1519	Transferase
LI64_RS00755	COG1216	Glycosyl transferase, family 2
LI64_RS00760	COG0438	transferase activity, transferring glycosyl groups
LI64_RS00770	COG0859	PFAM glycosyl transferase family 9
LI64_RS00795	COG0859	PFAM glycosyl transferase family 9
LI64_RS00800	COG0859	PFAM glycosyl transferase family 9
LI64_RS00815	COG1063	alcohol dehydrogenase
LI64_RS00830	COG2861	carbohydrate metabolic process
LI64_RS00835	COG4942	peptidase
LI64_RS00840	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LI64_RS00845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LI64_RS00850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LI64_RS00855	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LI64_RS00860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LI64_RS00870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI64_RS00880	COG0248	Ppx GppA phosphatase
LI64_RS00890	COG3118	belongs to the thioredoxin family
LI64_RS00895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LI64_RS00900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LI64_RS00910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LI64_RS00915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LI64_RS00920	COG0456	acetyltransferase
LI64_RS00925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LI64_RS00930	COG2244	polysaccharide biosynthetic process
LI64_RS00945	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LI64_RS00975	COG3071	HemY protein
LI64_RS00980	COG2959	enzyme of heme biosynthesis
LI64_RS00990	COG0181	hydroxymethylbilane synthase activity
LI64_RS01025	COG1011	Hydrolase
LI64_RS01030	COG0210	DNA helicase
LI64_RS01050	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LI64_RS01060	COG1280	lysine exporter protein (LysE YggA)
LI64_RS01065	COG1280	lysine exporter protein (LysE YggA)
LI64_RS01070	COG2267	carboxylic ester hydrolase activity
LI64_RS01075	COG0561	phosphatase activity
LI64_RS01080	COG0697	spore germination
LI64_RS01085	COG0583	DNA-binding transcription factor activity
LI64_RS01095	COG3842	ATPase activity
LI64_RS01105	COG1609	Transcriptional regulator
LI64_RS01115	COG1175	transmembrane transport
LI64_RS01120	COG0395	ABC-type sugar transport system, permease component
LI64_RS01125	COG0366	Alpha amylase catalytic
LI64_RS01135	COG0412	Dienelactone hydrolase
LI64_RS01145	COG1322	Protein conserved in bacteria
LI64_RS01150	COG2226	methyltransferase
LI64_RS01155	COG3165	ubiquinone biosynthetic process from chorismate
LI64_RS01160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LI64_RS01170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LI64_RS01175	COG0805	protein transport
LI64_RS01180	COG0084	hydrolase, TatD family'
LI64_RS01190	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LI64_RS01200	COG0488	(ABC) transporter
LI64_RS01205	COG2944	sequence-specific DNA binding
LI64_RS01220	COG1278	Cold shock
LI64_RS01225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LI64_RS01235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS01245	COG1609	Transcriptional regulator
LI64_RS01250	COG2885	chlorophyll binding
LI64_RS01255	COG0243	molybdopterin cofactor binding
LI64_RS01260	COG0456	acetyltransferase
LI64_RS01265	COG2818	Glycosylase
LI64_RS01270	COG5571	outer membrane autotransporter
LI64_RS01275	COG2223	nitrite transmembrane transporter activity
LI64_RS01315	COG0747	negative chemotaxis
LI64_RS01320	COG0601	transmembrane transport
LI64_RS01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI64_RS01330	COG0444	Belongs to the ABC transporter superfamily
LI64_RS01335	COG4608	Belongs to the ABC transporter superfamily
LI64_RS01340	COG1072	(Pantothenic acid kinase))
LI64_RS01380	COG0250	Participates in transcription elongation, termination and antitermination
LI64_RS01425	COG3706	GGDEF domain
LI64_RS01435	COG2022	thiamine diphosphate biosynthetic process
LI64_RS01440	COG2104	thiamine diphosphate biosynthetic process
LI64_RS01445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LI64_RS01460	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LI64_RS01470	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LI64_RS01475	COG1515	deoxyribonuclease V activity
LI64_RS01480	COG3068	Protein conserved in bacteria
LI64_RS01495	COG0151	Belongs to the GarS family
LI64_RS01525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LI64_RS01535	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LI64_RS01565	COG1187	pseudouridine synthase activity
LI64_RS01580	COG0527	aspartate kinase activity
LI64_RS01605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS01610	COG3223	Belongs to the PsiE family
LI64_RS01635	COG4580	involved in the transport of maltose and maltodextrins
LI64_RS01645	COG3161	chorismate lyase activity
LI64_RS01655	COG2937	Belongs to the GPAT DAPAT family
LI64_RS01660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LI64_RS01665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LI64_RS01670	COG0534	Mate efflux family protein
LI64_RS01675	COG3237	CsbD-like
LI64_RS01680	COG0735	belongs to the Fur family
LI64_RS01700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LI64_RS01710	COG0604	alcohol dehydrogenase
LI64_RS01715	COG0305	Participates in initiation and elongation during chromosome replication
LI64_RS01725	COG1448	Aminotransferase
LI64_RS01730	COG3700	Belongs to the class B bacterial acid phosphatase family
LI64_RS01740	COG2315	Protein conserved in bacteria
LI64_RS01750	COG0629	single-stranded DNA binding
LI64_RS01760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LI64_RS01770	COG0789	Transcriptional regulator
LI64_RS01775	COG0625	glutathione transferase activity
LI64_RS01780	COG2252	PERMEase
LI64_RS01785	COG0025	NhaP-type Na H and K H
LI64_RS01790	COG0583	DNA-binding transcription factor activity
LI64_RS01800	COG1346	cytolysis
LI64_RS01805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI64_RS01810	COG3162	membrane
LI64_RS01820	COG1301	dicarboxylic acid transport
LI64_RS01825	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LI64_RS01835	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS01840	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS01855	COG0191	fructose-bisphosphate aldolase activity
LI64_RS01870	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS01875	COG1129	ABC transporter
LI64_RS01880	COG4191	Histidine kinase
LI64_RS01880	COG0784	Response regulator, receiver
LI64_RS01890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LI64_RS01895	COG0456	acetyltransferase
LI64_RS01900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LI64_RS01905	COG3454	Phosphonate metabolism
LI64_RS01910	COG4778	phosphonate C-P lyase system protein PhnL
LI64_RS01915	COG4107	phosphonate C-P lyase system protein PhnK
LI64_RS01920	COG3627	carbon phosphorus lyase activity
LI64_RS01925	COG3626	phosphonate metabolism
LI64_RS01930	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LI64_RS01935	COG3624	Phosphonate C-P lyase system protein PhnG
LI64_RS01940	COG2188	Transcriptional regulator
LI64_RS01945	COG3639	organic phosphonate transmembrane transporter activity
LI64_RS01950	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LI64_RS01960	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LI64_RS01965	COG2824	Alkylphosphonate utilization operon protein PhnA
LI64_RS01970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LI64_RS01990	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LI64_RS02015	COG3647	Membrane
LI64_RS02035	COG1309	transcriptional regulator
LI64_RS02050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LI64_RS02055	COG1027	Aspartate ammonia-lyase
LI64_RS02060	COG3030	protein affecting phage T7 exclusion by the F plasmid
LI64_RS02065	COG0531	amino acid
LI64_RS02075	COG0459	protein refolding
LI64_RS02080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LI64_RS02085	COG0700	Nucleoside recognition
LI64_RS02090	COG3366	ferrous iron transmembrane transporter activity
LI64_RS02115	COG5510	response to toxic substance
LI64_RS02130	COG3040	lipid binding
LI64_RS02140	COG0583	DNA-binding transcription factor activity
LI64_RS02150	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LI64_RS02155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LI64_RS02160	COG1053	succinate dehydrogenase
LI64_RS02165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LI64_RS02175	COG1511	domain protein
LI64_RS02175	COG3264	Mechanosensitive ion channel
LI64_RS02210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LI64_RS02215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LI64_RS02215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LI64_RS02220	COG0802	atpase or kinase
LI64_RS02230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LI64_RS02235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LI64_RS02240	COG1923	regulation of RNA biosynthetic process
LI64_RS02245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LI64_RS02250	COG0330	HflC and HflK could
LI64_RS02255	COG0330	HflC and HflK could
LI64_RS02260	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LI64_RS02270	COG1959	2 iron, 2 sulfur cluster binding
LI64_RS02275	COG0557	exoribonuclease II activity
LI64_RS02280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI64_RS02285	COG0477	Major facilitator Superfamily
LI64_RS02290	COG1960	acyl-CoA dehydrogenase activity
LI64_RS02305	COG3650	response to hydrogen peroxide
LI64_RS02310	COG1073	alpha beta
LI64_RS02325	COG3037	sugar-specific permease SgaT UlaA
LI64_RS02365	COG2965	DNA replication, synthesis of RNA primer
LI64_RS02370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LI64_RS02375	COG0359	binds to the 23S rRNA
LI64_RS02380	COG0697	spore germination
LI64_RS02385	COG3061	Opacity-associated protein A
LI64_RS02390	COG0545	Peptidyl-prolyl cis-trans isomerase
LI64_RS02395	COG1113	amino acid transport
LI64_RS02405	COG0840	transmembrane signaling receptor activity
LI64_RS02410	COG0697	spore germination
LI64_RS02420	COG0702	epimerase
LI64_RS02425	COG1733	regulation of RNA biosynthetic process
LI64_RS02435	COG1218	3'(2'),5'-bisphosphate nucleotidase
LI64_RS02440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LI64_RS02450	COG1253	flavin adenine dinucleotide binding
LI64_RS02465	COG1609	Transcriptional regulator
LI64_RS02470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LI64_RS02475	COG0729	surface antigen
LI64_RS02480	COG2911	Protein conserved in bacteria
LI64_RS02485	COG2105	PFAM AIG2 family protein
LI64_RS02495	COG1879	ABC-type sugar transport system periplasmic component
LI64_RS02500	COG1129	ABC transporter
LI64_RS02505	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS02510	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS02525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LI64_RS02530	COG3028	Belongs to the UPF0307 family
LI64_RS02535	COG0312	modulator of DNA gyrase
LI64_RS02570	COG3964	amidohydrolase
LI64_RS02590	COG3711	transcriptional antiterminator
LI64_RS02590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS02595	COG0602	queuosine metabolic process
LI64_RS02605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS02605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS02630	COG0366	Alpha amylase catalytic
LI64_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS02635	COG1263	PTS System
LI64_RS02665	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LI64_RS02670	COG3397	chitin binding
LI64_RS02675	COG0251	oxidation-reduction process
LI64_RS02685	COG0540	Belongs to the ATCase OTCase family
LI64_RS02690	COG1438	arginine binding
LI64_RS02695	COG1288	antiporter activity
LI64_RS02710	COG2235	arginine
LI64_RS02715	COG2731	YhcH YjgK YiaL family protein
LI64_RS02720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LI64_RS02725	COG0129	dihydroxy-acid dehydratase activity
LI64_RS02730	COG2211	Major facilitator Superfamily
LI64_RS02735	COG3507	Belongs to the glycosyl hydrolase 43 family
LI64_RS02740	COG1414	Transcriptional regulator
LI64_RS02745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LI64_RS02770	COG0582	viral genome integration into host DNA
LI64_RS02825	COG0758	DNA mediated transformation
LI64_RS02840	COG1335	isochorismatase
LI64_RS02855	COG2204	response regulator
LI64_RS02860	COG4191	Histidine kinase
LI64_RS02865	COG4566	intracellular signal transduction
LI64_RS02870	COG0740	serine-type endopeptidase activity
LI64_RS02875	COG2850	peptidyl-arginine hydroxylation
LI64_RS02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI64_RS02895	COG5457	Domain of unknown function (DUF1127)
LI64_RS02905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI64_RS02910	COG0583	DNA-binding transcription factor activity
LI64_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS02930	COG0640	Transcriptional regulator
LI64_RS02940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS02950	COG2733	membrane
LI64_RS02955	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS02975	COG0523	cobalamin synthesis protein
LI64_RS02980	COG2879	small protein
LI64_RS02985	COG1966	Carbon starvation protein
LI64_RS02990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI64_RS02995	COG2368	4-hydroxyphenylacetate
LI64_RS03015	COG3971	2-oxopent-4-enoate hydratase activity
LI64_RS03025	COG3384	dioxygenase
LI64_RS03030	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS03035	COG0179	Fumarylacetoacetate (FAA) hydrolase
LI64_RS03040	COG1846	Transcriptional regulator
LI64_RS03045	COG0840	transmembrane signaling receptor activity
LI64_RS03100	COG1484	DNA-dependent DNA replication
LI64_RS03110	COG1764	response to oxidative stress
LI64_RS03115	COG1846	Transcriptional regulator
LI64_RS03120	COG3610	response to peptide
LI64_RS03125	COG2966	Psort location CytoplasmicMembrane, score
LI64_RS03130	COG2197	response regulator
LI64_RS03140	COG2197	response regulator
LI64_RS03145	COG2197	response regulator
LI64_RS03150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI64_RS03155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS03160	COG4114	ferric iron reductase
LI64_RS03190	COG2813	Specifically methylates the guanine in position
LI64_RS03195	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LI64_RS03200	COG0456	acetyltransferase
LI64_RS03205	COG1011	Hydrolase
LI64_RS03210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LI64_RS03215	COG2823	Periplasmic or secreted lipoprotein
LI64_RS03220	COG5487	UPF0391 membrane protein
LI64_RS03225	COG4667	esterase of the alpha-beta hydrolase superfamily
LI64_RS03230	COG0084	hydrolase, TatD family'
LI64_RS03235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI64_RS03240	COG1328	CTP reductase activity
LI64_RS03250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LI64_RS03275	COG3726	membrane protein affecting hemolysin expression
LI64_RS03280	COG0560	Phosphoserine phosphatase
LI64_RS03295	COG0604	alcohol dehydrogenase
LI64_RS03305	COG0488	(ABC) transporter
LI64_RS03310	COG0741	lytic transglycosylase activity
LI64_RS03315	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LI64_RS03320	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LI64_RS03325	COG0406	alpha-ribazole phosphatase activity
LI64_RS03330	COG2207	Transcriptional regulator
LI64_RS03330	COG3708	Transcriptional regulator
LI64_RS03335	COG3045	CreA protein
LI64_RS03340	COG0745	RESPONSE REGULATOR receiver
LI64_RS03345	COG2205	protein histidine kinase activity
LI64_RS03350	COG4452	Inner membrane protein CreD
LI64_RS03355	COG0745	RESPONSE REGULATOR receiver
LI64_RS03360	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LI64_RS03365	COG0460	homoserine dehydrogenase
LI64_RS03365	COG0527	aspartate kinase activity
LI64_RS03375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LI64_RS03390	COG1115	amino acid carrier protein
LI64_RS03400	COG0521	Mo-molybdopterin cofactor biosynthetic process
LI64_RS03405	COG0477	Major facilitator Superfamily
LI64_RS03410	COG1584	GPR1 FUN34 yaaH family protein
LI64_RS03420	COG0443	Heat shock 70 kDa protein
LI64_RS03430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LI64_RS03435	COG0583	DNA-binding transcription factor activity
LI64_RS03440	COG0268	Binds directly to 16S ribosomal RNA
LI64_RS03445	COG0196	riboflavin kinase activity
LI64_RS03460	COG1047	Peptidyl-prolyl cis-trans
LI64_RS03465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LI64_RS03470	COG2140	Oxalate decarboxylase
LI64_RS03480	COG3716	PTS system mannose fructose sorbose family IID component
LI64_RS03485	COG3715	PTS system
LI64_RS03490	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS03505	COG1609	Transcriptional regulator
LI64_RS03515	COG0505	Belongs to the CarA family
LI64_RS03540	COG0475	glutathione-regulated potassium exporter activity
LI64_RS03540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI64_RS03550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LI64_RS03555	COG2967	ApaG domain
LI64_RS03565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LI64_RS03570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI64_RS03575	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI64_RS03580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LI64_RS03585	COG0564	pseudouridine synthase activity
LI64_RS03590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LI64_RS03595	COG0417	DNA replication proofreading
LI64_RS03600	COG0235	Class ii aldolase
LI64_RS03605	COG2160	L-arabinose isomerase activity
LI64_RS03610	COG1069	ribulokinase activity
LI64_RS03620	COG0586	Pfam SNARE associated Golgi protein
LI64_RS03630	COG1178	ABC-type Fe3 transport system permease component
LI64_RS03650	COG2814	Major facilitator Superfamily
LI64_RS03675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LI64_RS03685	COG0028	Belongs to the TPP enzyme family
LI64_RS03695	COG1609	Transcriptional regulator
LI64_RS03700	COG2001	Belongs to the MraZ family
LI64_RS03715	COG0768	penicillin binding
LI64_RS03720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LI64_RS03725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LI64_RS03730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LI64_RS03740	COG0772	Belongs to the SEDS family
LI64_RS03755	COG1181	Belongs to the D-alanine--D-alanine ligase family
LI64_RS03765	COG0849	cell division
LI64_RS03770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LI64_RS03775	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LI64_RS03785	COG0653	protein targeting
LI64_RS03790	COG0494	nUDIX hydrolase
LI64_RS03795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LI64_RS03800	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LI64_RS03810	COG0516	GMP reductase activity
LI64_RS03815	COG1459	type II secretion system
LI64_RS03820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LI64_RS03825	COG4969	Belongs to the N-Me-Phe pilin family
LI64_RS03835	COG3023	N-Acetylmuramoyl-L-alanine amidase
LI64_RS03840	COG3725	Membrane protein required for beta-lactamase induction
LI64_RS03845	COG3940	Belongs to the glycosyl hydrolase 43 family
LI64_RS03850	COG2211	Major facilitator Superfamily
LI64_RS03855	COG1113	amino acid transport
LI64_RS03865	COG2186	Transcriptional regulator
LI64_RS03870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LI64_RS03875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LI64_RS03880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LI64_RS03895	COG3064	Membrane
LI64_RS03915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LI64_RS03925	COG2132	Multicopper oxidase
LI64_RS03930	COG4993	Dehydrogenase
LI64_RS04030	COG1802	Transcriptional regulator
LI64_RS04030	COG4626	Terminase
LI64_RS04045	COG0288	reversible hydration of carbon dioxide
LI64_RS04050	COG1131	(ABC) transporter
LI64_RS04055	COG0842	Transport permease protein
LI64_RS04060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS04065	COG0726	polysaccharide deacetylase
LI64_RS04090	COG3188	usher protein
LI64_RS04095	COG3121	Chaperone
LI64_RS04105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LI64_RS04110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LI64_RS04120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LI64_RS04125	COG0617	tRNA 3'-terminal CCA addition
LI64_RS04140	COG1489	DNA binding
LI64_RS04145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LI64_RS04150	COG1643	Atp-dependent helicase
LI64_RS04155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LI64_RS04160	COG4774	siderophore transport
LI64_RS04165	COG1120	ATPase activity
LI64_RS04170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LI64_RS04175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS04180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LI64_RS04190	COG0316	Belongs to the HesB IscA family
LI64_RS04195	COG2860	membrane
LI64_RS04205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LI64_RS04210	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LI64_RS04220	COG3835	regulator
LI64_RS04250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LI64_RS04265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LI64_RS04275	COG0575	Belongs to the CDS family
LI64_RS04280	COG0750	zinc metalloprotease
LI64_RS04285	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS04300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LI64_RS04305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI64_RS04310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI64_RS04315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LI64_RS04325	COG0825	malonyl-CoA metabolic process
LI64_RS04330	COG1982	Orn Lys Arg decarboxylase major
LI64_RS04335	COG0346	lactoylglutathione lyase activity
LI64_RS04340	COG0037	tRNA processing
LI64_RS04345	COG4568	rho-dependent transcription termination
LI64_RS04360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LI64_RS04365	COG3015	lipoprotein NlpE involved in copper resistance
LI64_RS04375	COG1720	tRNA m6t6A37 methyltransferase activity
LI64_RS04385	COG1464	Belongs to the NlpA lipoprotein family
LI64_RS04390	COG2011	ABC-type metal ion transport system permease component
LI64_RS04400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LI64_RS04440	COG0583	DNA-binding transcription factor activity
LI64_RS04445	COG2814	Major facilitator Superfamily
LI64_RS04450	COG3021	interspecies interaction between organisms
LI64_RS04455	COG2226	methyltransferase
LI64_RS04460	COG0741	lytic transglycosylase activity
LI64_RS04460	COG1388	LysM domain
LI64_RS04465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI64_RS04470	COG2226	methyltransferase
LI64_RS04490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI64_RS04495	COG1960	acyl-CoA dehydrogenase activity
LI64_RS04505	COG0121	glutamine amidotransferase
LI64_RS04510	COG3034	peptidoglycan biosynthetic process
LI64_RS04525	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LI64_RS04530	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LI64_RS04545	COG2991	Protein conserved in bacteria
LI64_RS04550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LI64_RS04555	COG2195	Cleaves the N-terminal amino acid of tripeptides
LI64_RS04565	COG1073	alpha beta
LI64_RS04575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI64_RS04580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LI64_RS04585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LI64_RS04615	COG2003	Belongs to the UPF0758 family
LI64_RS04630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LI64_RS04640	COG1902	pentaerythritol trinitrate reductase activity
LI64_RS04645	COG0583	DNA-binding transcription factor activity
LI64_RS04655	COG3300	MHYT domain
LI64_RS04655	COG5001	Diguanylate cyclase
LI64_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS04675	COG0583	DNA-binding transcription factor activity
LI64_RS04690	COG0628	permease
LI64_RS04695	COG0833	amino acid
LI64_RS04700	COG2040	homocysteine
LI64_RS04705	COG4521	taurine ABC transporter
LI64_RS04710	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LI64_RS04715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LI64_RS04720	COG2175	clavaminate synthase activity
LI64_RS04730	COG0113	porphobilinogen synthase activity
LI64_RS04745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LI64_RS04750	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LI64_RS04770	COG1181	Belongs to the D-alanine--D-alanine ligase family
LI64_RS04795	COG3706	GGDEF domain
LI64_RS04800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LI64_RS04805	COG1671	Belongs to the UPF0178 family
LI64_RS04810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI64_RS04820	COG4126	flavin adenine dinucleotide binding
LI64_RS04825	COG3123	guanosine phosphorylase activity
LI64_RS04835	COG1940	carbohydrate kinase activity
LI64_RS04840	COG0419	ATPase involved in DNA repair
LI64_RS04845	COG0420	3'-5' exonuclease activity
LI64_RS04855	COG5002	protein histidine kinase activity
LI64_RS04870	COG0366	Alpha amylase catalytic
LI64_RS04885	COG0450	alkyl hydroperoxide reductase
LI64_RS04890	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LI64_RS04905	COG1862	Preprotein translocase
LI64_RS04910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LI64_RS04915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LI64_RS04930	COG3248	Nucleoside-binding outer membrane protein
LI64_RS04935	COG4238	major outer membrane lipoprotein
LI64_RS04940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LI64_RS04945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LI64_RS04945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LI64_RS04950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LI64_RS04955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LI64_RS04960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LI64_RS04965	COG0667	Aldo Keto reductase
LI64_RS04970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LI64_RS04975	COG0142	geranyltranstransferase activity
LI64_RS05015	COG3539	Fimbrial protein
LI64_RS05020	COG2814	Major facilitator Superfamily
LI64_RS05025	COG0235	Class ii aldolase
LI64_RS05035	COG1070	Carbohydrate kinase
LI64_RS05045	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS05050	COG1129	ABC transporter
LI64_RS05070	COG0109	protoheme IX farnesyltransferase activity
LI64_RS05075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LI64_RS05080	COG1845	cytochrome c oxidase, subunit III
LI64_RS05085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LI64_RS05090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LI64_RS05100	COG2223	nitrite transmembrane transporter activity
LI64_RS05105	COG3056	Lipoprotein
LI64_RS05110	COG0271	Belongs to the BolA IbaG family
LI64_RS05115	COG0544	peptidyl-prolyl cis-trans isomerase activity
LI64_RS05130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LI64_RS05135	COG0776	regulation of translation
LI64_RS05140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI64_RS05145	COG1555	photosystem II stabilization
LI64_RS05150	COG0824	Thioesterase
LI64_RS05155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LI64_RS05160	COG4533	DNA binding
LI64_RS05165	COG0561	phosphatase activity
LI64_RS05175	COG1522	sequence-specific DNA binding
LI64_RS05180	COG1132	(ABC) transporter
LI64_RS05185	COG1132	(ABC) transporter
LI64_RS05190	COG0347	Belongs to the P(II) protein family
LI64_RS05195	COG0004	ammonium transporteR
LI64_RS05200	COG1946	Acyl-CoA thioesterase
LI64_RS05205	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LI64_RS05210	COG3695	enzyme binding
LI64_RS05225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI64_RS05230	COG2364	Membrane
LI64_RS05235	COG1609	Transcriptional regulator
LI64_RS05255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LI64_RS05265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LI64_RS05275	COG0110	maltose O-acetyltransferase activity
LI64_RS05290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS05295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS05300	COG1309	transcriptional regulator
LI64_RS05305	COG3264	Mechanosensitive ion channel
LI64_RS05305	COG1196	nuclear chromosome segregation
LI64_RS05315	COG3923	Primosomal replication protein n
LI64_RS05320	COG2832	Protein of unknown function (DUF454)
LI64_RS05325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LI64_RS05330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LI64_RS05335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LI64_RS05340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LI64_RS05345	COG0326	Molecular chaperone. Has ATPase activity
LI64_RS05355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LI64_RS05360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS05365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI64_RS05365	COG4651	solute:proton antiporter activity
LI64_RS05370	COG2223	nitrite transmembrane transporter activity
LI64_RS05375	COG0737	Belongs to the 5'-nucleotidase family
LI64_RS05380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI64_RS05385	COG3735	TraB family
LI64_RS05390	COG2217	Heavy metal translocating P-type atpase
LI64_RS05400	COG1585	Membrane protein implicated in regulation of membrane protease activity
LI64_RS05405	COG0330	HflC and HflK could
LI64_RS05415	COG4619	ABC transporter
LI64_RS05420	COG0390	transport system, permease component
LI64_RS05425	COG3118	belongs to the thioredoxin family
LI64_RS05430	COG0300	oxidoreductase activity
LI64_RS05435	COG2755	lipolytic protein G-D-S-L family
LI64_RS05440	COG4181	ATPase activity
LI64_RS05445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LI64_RS05460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LI64_RS05465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LI64_RS05470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI64_RS05475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LI64_RS05485	COG1988	membrane-bound metal-dependent
LI64_RS05490	COG1609	Transcriptional regulator
LI64_RS05495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS05495	COG2190	(PTS) system
LI64_RS05495	COG1263	PTS System
LI64_RS05500	COG2501	S4 domain
LI64_RS05560	COG0582	viral genome integration into host DNA
LI64_RS05620	COG4712	double-strand break repair protein
LI64_RS05775	COG5410	chromosome segregation
LI64_RS05885	COG2246	polysaccharide biosynthetic process
LI64_RS05910	COG1113	amino acid transport
LI64_RS05915	COG2211	Major facilitator Superfamily
LI64_RS05930	COG1609	Transcriptional regulator
LI64_RS05935	COG0668	transmembrane transport
LI64_RS05940	COG0477	Major facilitator Superfamily
LI64_RS05955	COG0778	Nitroreductase
LI64_RS05960	COG2315	Protein conserved in bacteria
LI64_RS05975	COG2207	Transcriptional regulator
LI64_RS06000	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LI64_RS06020	COG2826	transposase and inactivated derivatives, IS30 family
LI64_RS06035	COG5499	transcription regulator containing HTH domain
LI64_RS06100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LI64_RS06110	COG1121	(ABC) transporter
LI64_RS06115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI64_RS06120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI64_RS06125	COG2977	Belongs to the P-Pant transferase superfamily
LI64_RS06130	COG4771	TonB-dependent receptor
LI64_RS06135	COG2382	esterase
LI64_RS06140	COG3251	PFAM MbtH domain protein
LI64_RS06145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LI64_RS06145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LI64_RS06150	COG1120	ATPase activity
LI64_RS06155	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS06160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS06170	COG4592	Periplasmic binding protein
LI64_RS06175	COG1169	isochorismate synthase
LI64_RS06180	COG1021	2,3-dihydroxybenzoate-AMP ligase
LI64_RS06185	COG3433	isochorismatase activity
LI64_RS06185	COG1535	isochorismatase
LI64_RS06190	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS06195	COG2050	protein possibly involved in aromatic compounds catabolism
LI64_RS06200	COG1966	Carbon starvation protein
LI64_RS06205	COG2879	small protein
LI64_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS06225	COG0371	Dehydrogenase
LI64_RS06230	COG1129	ABC transporter
LI64_RS06235	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS06250	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LI64_RS06265	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LI64_RS06270	COG0235	Class ii aldolase
LI64_RS06275	COG0436	Aminotransferase
LI64_RS06280	COG1475	DNA binding
LI64_RS06285	COG3969	phosphoadenosine phosphosulfate
LI64_RS06290	COG0583	DNA-binding transcription factor activity
LI64_RS06310	COG1063	alcohol dehydrogenase
LI64_RS06315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LI64_RS06325	COG3719	Belongs to the RNase T2 family
LI64_RS06330	COG3069	C4-dicarboxylate transmembrane transporter activity
LI64_RS06350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS06355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS06370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LI64_RS06375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI64_RS06380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LI64_RS06385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LI64_RS06390	COG0583	DNA-binding transcription factor activity
LI64_RS06395	COG0321	lipoyl(octanoyl) transferase activity
LI64_RS06405	COG1686	Belongs to the peptidase S11 family
LI64_RS06410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LI64_RS06415	COG0772	Belongs to the SEDS family
LI64_RS06420	COG0768	penicillin binding
LI64_RS06430	COG0799	negative regulation of ribosome biogenesis
LI64_RS06440	COG1466	dna polymerase III delta subunit
LI64_RS06455	COG2888	peptidyl-tyrosine sulfation
LI64_RS06475	COG1957	nucleoside hydrolase
LI64_RS06480	COG1126	abc transporter atp-binding protein
LI64_RS06485	COG0765	amino acid transport
LI64_RS06490	COG0765	amino acid transport
LI64_RS06510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LI64_RS06515	COG1702	phosphate starvation-inducible protein PhoH
LI64_RS06520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LI64_RS06525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI64_RS06565	COG0367	asparagine synthase
LI64_RS06570	COG0647	UMP catabolic process
LI64_RS06575	COG1940	carbohydrate kinase activity
LI64_RS06575	COG1846	Transcriptional regulator
LI64_RS06580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LI64_RS06590	COG1263	PTS System
LI64_RS06590	COG2190	(PTS) system
LI64_RS06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS06595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LI64_RS06610	COG0735	belongs to the Fur family
LI64_RS06625	COG0596	Alpha beta hydrolase
LI64_RS06635	COG0033	Phosphoglucomutase
LI64_RS06640	COG0531	amino acid
LI64_RS06645	COG1982	Orn Lys Arg decarboxylase major
LI64_RS06650	COG0745	RESPONSE REGULATOR receiver
LI64_RS06655	COG2205	protein histidine kinase activity
LI64_RS06660	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LI64_RS06665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LI64_RS06670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LI64_RS06690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LI64_RS06695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LI64_RS06700	COG1984	allophanate hydrolase subunit 2
LI64_RS06710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LI64_RS06715	COG0372	Belongs to the citrate synthase family
LI64_RS06720	COG2009	succinate dehydrogenase
LI64_RS06725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LI64_RS06730	COG1053	succinate dehydrogenase
LI64_RS06735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LI64_RS06740	COG0567	Dehydrogenase, E1 component
LI64_RS06745	COG0508	dehydrogenase complex catalyzes the overall conversion of
LI64_RS06750	COG0045	succinate-CoA ligase (ADP-forming) activity
LI64_RS06755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LI64_RS06770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LI64_RS06775	COG2188	Transcriptional regulator
LI64_RS06780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS06780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS06780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS06785	COG0383	alpha-mannosidase activity
LI64_RS06790	COG1271	oxidase subunit
LI64_RS06795	COG1294	oxidase, subunit
LI64_RS06800	COG4890	Cyd operon protein YbgT
LI64_RS06805	COG3790	cyd operon protein YbgE
LI64_RS06810	COG0824	Thioesterase
LI64_RS06815	COG0811	peptide transport
LI64_RS06820	COG0848	biopolymer transport protein
LI64_RS06825	COG3064	Membrane
LI64_RS06830	COG0823	Involved in the tonB-independent uptake of proteins
LI64_RS06835	COG2885	chlorophyll binding
LI64_RS06840	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LI64_RS06875	COG3201	nicotinamide mononucleotide transporter
LI64_RS06880	COG1230	cation diffusion facilitator family transporter
LI64_RS06890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI64_RS06905	COG2017	converts alpha-aldose to the beta-anomer
LI64_RS06910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LI64_RS06915	COG1085	galactose-1-phosphate uridylyltransferase
LI64_RS06920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LI64_RS06925	COG1119	ATPase activity
LI64_RS06930	COG3585	molybdate ion transport
LI64_RS06930	COG2005	Transcriptional regulator
LI64_RS06940	COG0725	ABC transporter, periplasmic molybdate-binding protein
LI64_RS06945	COG4149	molybdate abc transporter
LI64_RS06955	COG0561	phosphatase activity
LI64_RS06960	COG2706	6-phosphogluconolactonase activity
LI64_RS06965	COG4677	pectinesterase activity
LI64_RS06975	COG0010	Belongs to the arginase family
LI64_RS06985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LI64_RS06990	COG2986	histidine ammonia-lyase
LI64_RS06995	COG1881	PFAM PEBP family protein
LI64_RS07000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LI64_RS07005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LI64_RS07010	COG0156	8-amino-7-oxononanoate synthase activity
LI64_RS07015	COG2226	methyltransferase
LI64_RS07045	COG0521	Mo-molybdopterin cofactor biosynthetic process
LI64_RS07050	COG0315	cyclic pyranopterin monophosphate synthase activity
LI64_RS07055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LI64_RS07060	COG0314	molybdopterin synthase activity
LI64_RS07065	COG0670	Belongs to the BI1 family
LI64_RS07070	COG0392	lysyltransferase activity
LI64_RS07075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LI64_RS07080	COG3568	Endonuclease Exonuclease Phosphatase
LI64_RS07090	COG0842	Transport permease protein
LI64_RS07095	COG0842	Transport permease protein
LI64_RS07100	COG1131	(ABC) transporter
LI64_RS07105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS07110	COG1309	transcriptional regulator
LI64_RS07115	COG0513	Belongs to the DEAD box helicase family
LI64_RS07120	COG1199	ATP-dependent helicase activity
LI64_RS07140	COG3121	Chaperone
LI64_RS07145	COG3539	Fimbrial protein
LI64_RS07150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LI64_RS07160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LI64_RS07175	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LI64_RS07180	COG0668	transmembrane transport
LI64_RS07185	COG1126	abc transporter atp-binding protein
LI64_RS07190	COG0765	amino acid transport
LI64_RS07195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS07200	COG0783	Belongs to the Dps family
LI64_RS07210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LI64_RS07215	COG2194	sulfuric ester hydrolase activity
LI64_RS07225	COG1321	iron dependent repressor
LI64_RS07230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LI64_RS07235	COG1566	PFAM secretion protein HlyD family protein
LI64_RS07240	COG2814	Major facilitator Superfamily
LI64_RS07250	COG2723	6-phospho-beta-galactosidase activity
LI64_RS07255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS07260	COG2188	Transcriptional regulator
LI64_RS07265	COG1376	ErfK ybiS ycfS ynhG family protein
LI64_RS07270	COG0488	(ABC) transporter
LI64_RS07280	COG2271	Major facilitator Superfamily
LI64_RS07285	COG1609	Transcriptional regulator
LI64_RS07295	COG0561	phosphatase activity
LI64_RS07300	COG1882	Formate acetyltransferase
LI64_RS07305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI64_RS07310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LI64_RS07315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LI64_RS07320	COG0303	'Molybdopterin
LI64_RS07325	COG1446	asparaginase
LI64_RS07360	COG2133	pyrroloquinoline quinone binding
LI64_RS07365	COG0625	glutathione transferase activity
LI64_RS07370	COG1686	Belongs to the peptidase S11 family
LI64_RS07375	COG1349	DNA-binding transcription factor activity
LI64_RS07380	COG0671	phosphoesterase, PA-phosphatase related
LI64_RS07390	COG2814	Major facilitator Superfamily
LI64_RS07395	COG0561	phosphatase activity
LI64_RS07405	COG3226	Transcriptional regulator
LI64_RS07410	COG1393	Belongs to the ArsC family
LI64_RS07445	COG0778	Nitroreductase
LI64_RS07460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LI64_RS07465	COG3842	ATPase activity
LI64_RS07470	COG1176	ABC-type spermidine putrescine transport system, permease component I
LI64_RS07475	COG1177	transmembrane transport
LI64_RS07485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI64_RS07490	COG0745	RESPONSE REGULATOR receiver
LI64_RS07495	COG5002	protein histidine kinase activity
LI64_RS07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS07505	COG4160	amino acid transport
LI64_RS07510	COG4215	(ABC) transporter
LI64_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS07520	COG1126	abc transporter atp-binding protein
LI64_RS07530	COG0393	Putative heavy-metal-binding
LI64_RS07535	COG3023	N-Acetylmuramoyl-L-alanine amidase
LI64_RS07560	COG1450	Type ii and iii secretion system protein
LI64_RS07565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LI64_RS07570	COG1459	type II secretion system
LI64_RS07575	COG2165	general secretion pathway protein
LI64_RS07585	COG2165	general secretion pathway protein
LI64_RS07610	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LI64_RS07630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI64_RS07635	COG0702	epimerase
LI64_RS07640	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LI64_RS07645	COG0028	Belongs to the TPP enzyme family
LI64_RS07650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI64_RS07655	COG1151	hydroxylamine reductase activity
LI64_RS07660	COG2431	L-lysine efflux transmembrane transporter activity
LI64_RS07670	COG3593	DNA synthesis involved in DNA repair
LI64_RS07680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS07690	COG1278	Cold shock
LI64_RS07695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LI64_RS07700	COG0542	response to heat
LI64_RS07710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LI64_RS07715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LI64_RS07720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LI64_RS07725	COG4988	ABC transporter
LI64_RS07730	COG0492	ferredoxin-NADP+ reductase activity
LI64_RS07740	COG1674	ftsk spoiiie
LI64_RS07740	COG1178	ABC-type Fe3 transport system permease component
LI64_RS07745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LI64_RS07750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LI64_RS07755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LI64_RS07760	COG0243	molybdopterin cofactor binding
LI64_RS07765	COG0437	4 iron, 4 sulfur cluster binding
LI64_RS07770	COG3302	dmso reductase anchor subunit
LI64_RS07775	COG0477	Major facilitator Superfamily
LI64_RS07785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI64_RS07790	COG1882	Formate acetyltransferase
LI64_RS07795	COG2116	formate transmembrane transporter activity
LI64_RS07800	COG1944	ATP diphosphatase activity
LI64_RS07805	COG2323	membrane
LI64_RS07810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LI64_RS07815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LI64_RS07820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LI64_RS07825	COG0539	negative regulation of cytoplasmic translation
LI64_RS07830	COG0776	regulation of translation
LI64_RS07835	COG2333	competence protein COMEC
LI64_RS07835	COG0658	competence protein
LI64_RS07840	COG1132	(ABC) transporter
LI64_RS07850	COG3214	Protein conserved in bacteria
LI64_RS07855	COG2835	tetraacyldisaccharide 4'-kinase activity
LI64_RS07860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LI64_RS07865	COG3173	Aminoglycoside phosphotransferase
LI64_RS07870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LI64_RS07875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LI64_RS07885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LI64_RS07890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LI64_RS07895	COG2989	Protein conserved in bacteria
LI64_RS07900	COG3108	Peptidase M15
LI64_RS07905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI64_RS07910	COG1448	Aminotransferase
LI64_RS07920	COG0017	Asparaginyl-tRNA synthetase
LI64_RS07925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LI64_RS07930	COG0308	aminopeptidase N
LI64_RS07940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LI64_RS07945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS07950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LI64_RS07955	COG0431	NADPH-dependent FMN reductase
LI64_RS07960	COG0167	dihydroorotate dehydrogenase activity
LI64_RS07970	COG3217	Mosc domain protein beta barrel domain protein
LI64_RS07970	COG0633	Ferredoxin
LI64_RS07975	COG0116	Belongs to the methyltransferase superfamily
LI64_RS07975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LI64_RS07980	COG0488	(ABC) transporter
LI64_RS07985	COG2995	paraquat-inducible protein a
LI64_RS07990	COG3008	intermembrane lipid transfer
LI64_RS07990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LI64_RS07995	COG3009	Protein conserved in bacteria
LI64_RS08000	COG3130	regulation of translation
LI64_RS08010	COG1067	ATP-dependent peptidase activity
LI64_RS08015	COG3120	sequence-specific DNA binding
LI64_RS08025	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LI64_RS08035	COG1289	transmembrane transporter activity
LI64_RS08040	COG3304	Inner membrane component domain
LI64_RS08045	COG0210	DNA helicase
LI64_RS08050	COG1803	Methylglyoxal synthase
LI64_RS08055	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LI64_RS08060	COG1832	CoA-binding protein
LI64_RS08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LI64_RS08075	COG1254	Belongs to the acylphosphatase family
LI64_RS08085	COG0670	Belongs to the BI1 family
LI64_RS08100	COG1120	ATPase activity
LI64_RS08105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS08115	COG3264	Mechanosensitive ion channel
LI64_RS08115	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LI64_RS08125	COG2826	transposase and inactivated derivatives, IS30 family
LI64_RS08140	COG2239	Acts as a magnesium transporter
LI64_RS08145	COG0586	Pfam SNARE associated Golgi protein
LI64_RS08165	COG3729	General stress protein
LI64_RS08185	COG2233	PERMEase
LI64_RS08190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI64_RS08195	COG0778	Nitroreductase
LI64_RS08200	COG2267	carboxylic ester hydrolase activity
LI64_RS08205	COG0251	oxidation-reduction process
LI64_RS08210	COG1335	isochorismatase
LI64_RS08215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS08220	COG1309	transcriptional regulator
LI64_RS08230	COG0506	proline dehydrogenase activity
LI64_RS08230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LI64_RS08230	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LI64_RS08235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI64_RS08245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LI64_RS08265	COG1702	phosphate starvation-inducible protein PhoH
LI64_RS08270	COG1115	amino acid carrier protein
LI64_RS08280	COG1335	isochorismatase
LI64_RS08290	COG0583	DNA-binding transcription factor activity
LI64_RS08300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI64_RS08305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LI64_RS08310	COG3381	protein complex oligomerization
LI64_RS08370	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LI64_RS08385	COG2943	transferase activity, transferring hexosyl groups
LI64_RS08390	COG5645	(Lipo)protein
LI64_RS08405	COG1560	Kdo2-lipid A biosynthetic process
LI64_RS08410	COG1054	Belongs to the UPF0176 family
LI64_RS08415	COG2353	YceI-like domain
LI64_RS08420	COG3038	cytochrome b561
LI64_RS08445	COG0418	dihydroorotase activity
LI64_RS08455	COG0477	Major facilitator Superfamily
LI64_RS08460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI64_RS08465	COG3132	Protein of unknown function, DUF480
LI64_RS08500	COG1558	bacterial-type flagellum-dependent cell motility
LI64_RS08520	COG4786	Flagellar basal body rod
LI64_RS08540	COG1256	bacterial-type flagellum assembly
LI64_RS08550	COG2814	Major facilitator Superfamily
LI64_RS08555	COG0583	DNA-binding transcription factor activity
LI64_RS08560	COG1530	ribonuclease E activity
LI64_RS08565	COG0564	pseudouridine synthase activity
LI64_RS08570	COG0424	maF-like protein
LI64_RS08580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LI64_RS08585	COG0416	fatty acid biosynthetic process
LI64_RS08590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LI64_RS08605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LI64_RS08610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI64_RS08615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LI64_RS08620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LI64_RS08625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LI64_RS08630	COG0470	DNA polymerase III
LI64_RS08635	COG0084	hydrolase, TatD family'
LI64_RS08645	COG4773	Receptor
LI64_RS08650	COG0537	adenosine 5'-monophosphoramidase activity
LI64_RS08655	COG5633	Lipoprotein
LI64_RS08660	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LI64_RS08675	COG3150	esterase
LI64_RS08680	COG1252	NADH dehydrogenase
LI64_RS08685	COG3134	Outer membrane lipoprotein
LI64_RS08690	COG1309	transcriptional regulator
LI64_RS08700	COG1388	LysM domain
LI64_RS08700	COG1376	ErfK ybiS ycfS ynhG family protein
LI64_RS08705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LI64_RS08710	COG4763	Acyl-transferase
LI64_RS08715	COG4591	ABC-type transport system involved in lipoprotein release permease component
LI64_RS08720	COG1136	(ABC) transporter
LI64_RS08725	COG4591	ABC-type transport system involved in lipoprotein release permease component
LI64_RS08735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LI64_RS08770	COG1943	Transposase
LI64_RS08775	COG2850	peptidyl-arginine hydroxylation
LI64_RS08780	COG2205	protein histidine kinase activity
LI64_RS08795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LI64_RS08800	COG2915	High frequency lysogenization protein hflD homolog
LI64_RS08815	COG1187	pseudouridine synthase activity
LI64_RS08820	COG0538	isocitrate dehydrogenase activity
LI64_RS08830	COG5001	Diguanylate cyclase
LI64_RS08835	COG2261	transglycosylase associated protein
LI64_RS08845	COG2203	Gaf domain
LI64_RS08845	COG2199	diguanylate cyclase activity
LI64_RS08850	COG3042	response to heat
LI64_RS08860	COG3189	MarR family transcriptional regulator
LI64_RS08865	COG0504	CTP synthase activity
LI64_RS08870	COG2807	transmembrane transport
LI64_RS08875	COG2207	Transcriptional regulator
LI64_RS08890	COG2211	Major facilitator Superfamily
LI64_RS08895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI64_RS08900	COG2718	Belongs to the UPF0229 family
LI64_RS08905	COG2766	serine protein kinase
LI64_RS08910	COG3713	MltA-interacting MipA family protein
LI64_RS08930	COG3139	Protein of unknown function (DUF1315)
LI64_RS08940	COG1335	isochorismatase
LI64_RS08945	COG0252	asparaginase activity
LI64_RS08950	COG0616	signal peptide processing
LI64_RS08955	COG0778	Nitroreductase
LI64_RS08960	COG0709	Synthesizes selenophosphate from selenide and ATP
LI64_RS08965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LI64_RS08975	COG0641	radical SAM
LI64_RS08980	COG2190	(PTS) system
LI64_RS08980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS08980	COG1263	PTS System
LI64_RS08995	COG1737	Transcriptional regulator
LI64_RS09000	COG2149	membrane
LI64_RS09020	COG0494	nUDIX hydrolase
LI64_RS09025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI64_RS09030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LI64_RS09035	COG2897	thiosulfate sulfurtransferase activity
LI64_RS09040	COG4136	ATPase activity
LI64_RS09045	COG4135	transport system, permease component
LI64_RS09050	COG4134	Bacterial extracellular solute-binding protein
LI64_RS09060	COG0708	Exodeoxyribonuclease III
LI64_RS09070	COG3138	arginine N-succinyltransferase
LI64_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS09080	COG3724	N-succinylarginine dihydrolase activity
LI64_RS09090	COG3678	ATP-independent chaperone mediated protein folding
LI64_RS09100	COG0322	excinuclease ABC activity
LI64_RS09110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS09115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS09120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS09125	COG1447	Phosphotransferase system cellobiose-specific component IIA
LI64_RS09130	COG1917	Cupin 2, conserved barrel domain protein
LI64_RS09130	COG2169	Transcriptional regulator
LI64_RS09135	COG1486	melibiose metabolic process
LI64_RS09140	COG3394	polysaccharide catabolic process
LI64_RS09145	COG0753	catalase activity
LI64_RS09155	COG1823	symporter activity
LI64_RS09160	COG1988	membrane-bound metal-dependent
LI64_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS09170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI64_RS09180	COG3001	Fructosamine kinase
LI64_RS09190	COG1105	Belongs to the carbohydrate kinase PfkB family
LI64_RS09195	COG3137	Salt-induced outer membrane protein
LI64_RS09225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LI64_RS09230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LI64_RS09230	COG0072	phenylalanine-tRNA ligase activity
LI64_RS09235	COG0776	regulation of translation
LI64_RS09245	COG0386	Belongs to the glutathione peroxidase family
LI64_RS09255	COG0791	NLP P60 protein
LI64_RS09265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LI64_RS09275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS09280	COG4558	Periplasmic binding protein
LI64_RS09285	COG3720	iron ion transport
LI64_RS09295	COG4256	Hemin uptake protein
LI64_RS09300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI64_RS09305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LI64_RS09310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LI64_RS09310	COG0574	Belongs to the PEP-utilizing enzyme family
LI64_RS09315	COG2211	Major facilitator Superfamily
LI64_RS09320	COG1472	Belongs to the glycosyl hydrolase 3 family
LI64_RS09325	COG0628	permease
LI64_RS09330	COG0277	FAD linked oxidase domain protein
LI64_RS09330	COG0247	lactate metabolic process
LI64_RS09335	COG2050	protein possibly involved in aromatic compounds catabolism
LI64_RS09345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LI64_RS09360	COG3121	Chaperone
LI64_RS09375	COG3539	Fimbrial protein
LI64_RS09400	COG2200	EAL domain
LI64_RS09405	COG0789	Transcriptional regulator
LI64_RS09410	COG0316	Belongs to the HesB IscA family
LI64_RS09415	COG0719	Fe-S assembly protein
LI64_RS09420	COG0396	ATPase activity
LI64_RS09425	COG0719	Fe-S assembly protein
LI64_RS09430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LI64_RS09435	COG2166	iron-sulfur cluster assembly
LI64_RS09440	COG1376	ErfK ybiS ycfS ynhG family protein
LI64_RS09460	COG2011	ABC-type metal ion transport system permease component
LI64_RS09465	COG1464	Belongs to the NlpA lipoprotein family
LI64_RS09475	COG0765	amino acid transport
LI64_RS09480	COG0765	amino acid transport
LI64_RS09490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI64_RS09520	COG4529	Protein conserved in bacteria
LI64_RS09560	COG0307	riboflavin synthase, alpha
LI64_RS09565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LI64_RS09570	COG2814	Major facilitator Superfamily
LI64_RS09575	COG0583	DNA-binding transcription factor activity
LI64_RS09590	COG2814	Major facilitator Superfamily
LI64_RS09600	COG0791	NLP P60 protein
LI64_RS09605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LI64_RS09615	COG0346	lactoylglutathione lyase activity
LI64_RS09620	COG1902	pentaerythritol trinitrate reductase activity
LI64_RS09625	COG1309	transcriptional regulator
LI64_RS09630	COG2194	sulfuric ester hydrolase activity
LI64_RS09635	COG3313	Fe-S protein
LI64_RS09640	COG4989	oxidoreductase activity
LI64_RS09645	COG2032	superoxide dismutase activity
LI64_RS09650	COG1289	transmembrane transporter activity
LI64_RS09655	COG1566	PFAM secretion protein HlyD family protein
LI64_RS09670	COG3706	GGDEF domain
LI64_RS09680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LI64_RS09685	COG3895	Periplasmic Protein
LI64_RS09690	COG0259	pyridoxamine-phosphate oxidase activity
LI64_RS09695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LI64_RS09700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LI64_RS09705	COG0625	glutathione transferase activity
LI64_RS09710	COG3104	oligopeptide transport
LI64_RS09715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LI64_RS09765	COG0673	inositol 2-dehydrogenase activity
LI64_RS09770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LI64_RS09775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LI64_RS09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS09780	COG1263	PTS System
LI64_RS09785	COG1609	Transcriptional regulator
LI64_RS09790	COG5339	Protein conserved in bacteria
LI64_RS09795	COG1482	cell wall glycoprotein biosynthetic process
LI64_RS09800	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LI64_RS09800	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LI64_RS09815	COG2205	protein histidine kinase activity
LI64_RS09840	COG1278	Cold shock
LI64_RS09850	COG0745	RESPONSE REGULATOR receiver
LI64_RS09855	COG3136	membrane protein required for alginate biosynthesis
LI64_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS09865	COG0531	amino acid
LI64_RS09875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LI64_RS09880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LI64_RS09885	COG0668	transmembrane transport
LI64_RS09890	COG0589	response to stress
LI64_RS09900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LI64_RS09905	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LI64_RS09910	COG1473	amidohydrolase
LI64_RS09920	COG0583	DNA-binding transcription factor activity
LI64_RS09925	COG2840	Smr protein MutS2
LI64_RS09935	COG0667	Aldo Keto reductase
LI64_RS09950	COG4993	Dehydrogenase
LI64_RS09985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LI64_RS09990	COG1403	HNH endonuclease
LI64_RS09995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS10005	COG0628	permease
LI64_RS10010	COG2076	Multidrug Resistance protein
LI64_RS10015	COG2076	Multidrug Resistance protein
LI64_RS10020	COG3591	Belongs to the peptidase S1B family
LI64_RS10030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LI64_RS10050	COG2814	Major facilitator Superfamily
LI64_RS10055	COG0583	DNA-binding transcription factor activity
LI64_RS10060	COG1940	carbohydrate kinase activity
LI64_RS10065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LI64_RS10135	COG3141	response to X-ray
LI64_RS10140	COG3381	protein complex oligomerization
LI64_RS10145	COG3302	dmso reductase anchor subunit
LI64_RS10155	COG0243	molybdopterin cofactor binding
LI64_RS10205	COG0243	molybdopterin cofactor binding
LI64_RS10225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI64_RS10235	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS10240	COG1063	alcohol dehydrogenase
LI64_RS10245	COG0477	Major facilitator Superfamily
LI64_RS10250	COG0246	Mannitol dehydrogenase
LI64_RS10260	COG0589	response to stress
LI64_RS10265	COG1802	Transcriptional regulator
LI64_RS10270	COG4221	oxidoreductase activity
LI64_RS10285	COG0814	amino acid
LI64_RS10295	COG4993	Dehydrogenase
LI64_RS10320	COG0745	RESPONSE REGULATOR receiver
LI64_RS10345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LI64_RS10350	COG2911	Protein conserved in bacteria
LI64_RS10360	COG3784	Protein of unknown function (DUF1318)
LI64_RS10365	COG2207	Transcriptional regulator
LI64_RS10370	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS10375	COG5001	Diguanylate cyclase
LI64_RS10375	COG4251	negative regulation of phosphorylation
LI64_RS10375	COG2203	Gaf domain
LI64_RS10375	COG3706	GGDEF domain
LI64_RS10380	COG3733	amine oxidase
LI64_RS10385	COG2030	dehydratase
LI64_RS10385	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS10390	COG3396	Phenylacetate-CoA oxygenase
LI64_RS10395	COG3460	Phenylacetate-CoA oxygenase
LI64_RS10400	COG3396	Phenylacetate-CoA oxygenase
LI64_RS10405	COG2151	metal-sulfur cluster biosynthetic enzyme
LI64_RS10410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI64_RS10415	COG1024	Enoyl-CoA hydratase
LI64_RS10420	COG1024	Enoyl-CoA hydratase
LI64_RS10425	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI64_RS10430	COG2050	protein possibly involved in aromatic compounds catabolism
LI64_RS10435	COG0183	Belongs to the thiolase family
LI64_RS10440	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LI64_RS10445	COG3327	negative regulation of DNA-templated transcription, initiation
LI64_RS10450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI64_RS10455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LI64_RS10475	COG0300	oxidoreductase activity
LI64_RS10490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LI64_RS10535	COG3122	Protein conserved in bacteria
LI64_RS10540	COG0564	pseudouridine synthase activity
LI64_RS10550	COG1643	Atp-dependent helicase
LI64_RS10555	COG4122	O-methyltransferase activity
LI64_RS10560	COG1538	Outer membrane efflux protein
LI64_RS10575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LI64_RS10580	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS10590	COG3038	cytochrome b561
LI64_RS10595	COG0673	inositol 2-dehydrogenase activity
LI64_RS10600	COG1349	DNA-binding transcription factor activity
LI64_RS10615	COG2274	protein secretion by the type I secretion system
LI64_RS10665	COG0840	transmembrane signaling receptor activity
LI64_RS10675	COG0513	Belongs to the DEAD box helicase family
LI64_RS10685	COG0582	viral genome integration into host DNA
LI64_RS10700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI64_RS10705	COG0674	pyruvate-flavodoxin oxidoreductase activity
LI64_RS10705	COG1013	pyruvate-flavodoxin oxidoreductase activity
LI64_RS10705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI64_RS10705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LI64_RS10710	COG3042	response to heat
LI64_RS10715	COG3187	Heat shock protein
LI64_RS10725	COG1294	oxidase, subunit
LI64_RS10730	COG1271	oxidase subunit
LI64_RS10740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI64_RS10745	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS10755	COG3615	Tellurite resistance protein tehB
LI64_RS10760	COG3615	Tellurite resistance protein tehB
LI64_RS10790	COG0747	negative chemotaxis
LI64_RS10800	COG3238	Protein conserved in bacteria
LI64_RS10805	COG1247	-acetyltransferase
LI64_RS10815	COG2130	NADP-dependent
LI64_RS10820	COG1802	Transcriptional regulator
LI64_RS10825	COG4772	TonB-dependent receptor
LI64_RS10845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI64_RS10850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS10855	COG1473	amidohydrolase
LI64_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS10865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LI64_RS10880	COG1126	abc transporter atp-binding protein
LI64_RS10890	COG0625	glutathione transferase activity
LI64_RS10895	COG1942	4-Oxalocrotonate Tautomerase
LI64_RS10900	COG1560	Kdo2-lipid A biosynthetic process
LI64_RS10910	COG0640	Transcriptional regulator
LI64_RS10915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LI64_RS10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI64_RS10935	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LI64_RS10940	COG2181	nitrate reductase activity
LI64_RS10945	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LI64_RS10950	COG1140	nitrate reductase beta subunit
LI64_RS10955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LI64_RS10985	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS10985	COG0243	molybdopterin cofactor binding
LI64_RS10990	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS10990	COG0243	molybdopterin cofactor binding
LI64_RS10995	COG0437	4 iron, 4 sulfur cluster binding
LI64_RS11000	COG2864	formate dehydrogenase
LI64_RS11010	COG2814	Major facilitator Superfamily
LI64_RS11015	COG1064	alcohol dehydrogenase
LI64_RS11020	COG0488	(ABC) transporter
LI64_RS11025	COG0281	malic enzyme
LI64_RS11055	COG1764	response to oxidative stress
LI64_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS11070	COG4608	Belongs to the ABC transporter superfamily
LI64_RS11075	COG0444	Belongs to the ABC transporter superfamily
LI64_RS11080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI64_RS11085	COG0601	transmembrane transport
LI64_RS11090	COG0747	negative chemotaxis
LI64_RS11095	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LI64_RS11110	COG2200	EAL domain
LI64_RS11140	COG0840	transmembrane signaling receptor activity
LI64_RS11155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LI64_RS11160	COG1649	PFAM Uncharacterised BCR, COG1649
LI64_RS11165	COG4628	conserved protein (DUF2132)
LI64_RS11170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LI64_RS11175	COG0583	DNA-binding transcription factor activity
LI64_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS11195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LI64_RS11230	COG2814	Major facilitator Superfamily
LI64_RS11280	COG0714	Associated with various cellular activities
LI64_RS11285	COG0641	radical SAM
LI64_RS11290	COG3119	arylsulfatase activity
LI64_RS11305	COG2067	long-chain fatty acid transport protein
LI64_RS11320	COG0583	DNA-binding transcription factor activity
LI64_RS11335	COG0583	DNA-binding transcription factor activity
LI64_RS11340	COG2076	Multidrug Resistance protein
LI64_RS11360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LI64_RS11400	COG3039	Transposase
LI64_RS11430	COG0110	maltose O-acetyltransferase activity
LI64_RS11440	COG1349	DNA-binding transcription factor activity
LI64_RS11445	COG0494	nUDIX hydrolase
LI64_RS11450	COG4106	trans-aconitate 2-methyltransferase activity
LI64_RS11470	COG0596	Alpha beta hydrolase
LI64_RS11495	COG3781	membrane
LI64_RS11500	COG0246	Mannitol dehydrogenase
LI64_RS11510	COG3706	GGDEF domain
LI64_RS11520	COG2066	Belongs to the glutaminase family
LI64_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS11535	COG0583	DNA-binding transcription factor activity
LI64_RS11550	COG2814	Major facilitator Superfamily
LI64_RS11560	COG1846	Transcriptional regulator
LI64_RS11575	COG0697	spore germination
LI64_RS11580	COG2814	Major facilitator Superfamily
LI64_RS11585	COG3443	Belongs to the bacterial solute-binding protein 9 family
LI64_RS11595	COG1129	ABC transporter
LI64_RS11615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LI64_RS11640	COG0826	peptidase U32
LI64_RS11645	COG1396	sequence-specific DNA binding
LI64_RS11650	COG3135	benzoate transporter
LI64_RS11670	COG0747	negative chemotaxis
LI64_RS11675	COG2195	Cleaves the N-terminal amino acid of tripeptides
LI64_RS11680	COG0500	methyltransferase
LI64_RS11685	COG1275	C4-dicarboxylate transporter malic acid transport protein
LI64_RS11690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI64_RS11695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI64_RS11700	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LI64_RS11710	COG0436	Aminotransferase
LI64_RS11720	COG2272	Belongs to the type-B carboxylesterase lipase family
LI64_RS11725	COG5383	Protein conserved in bacteria
LI64_RS11730	COG0583	DNA-binding transcription factor activity
LI64_RS11735	COG0840	transmembrane signaling receptor activity
LI64_RS11795	COG4166	transmembrane transport
LI64_RS11800	COG2866	Carboxypeptidase
LI64_RS11805	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS11810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LI64_RS11820	COG3768	UPF0283 membrane protein
LI64_RS11825	COG3106	COG3106 Predicted ATPase
LI64_RS11830	COG1609	Transcriptional regulator
LI64_RS11840	COG3842	ATPase activity
LI64_RS11845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI64_RS11850	COG1554	hydrolase, family 65, central catalytic
LI64_RS11855	COG0673	inositol 2-dehydrogenase activity
LI64_RS11860	COG1082	Xylose isomerase domain protein TIM barrel
LI64_RS11865	COG1063	alcohol dehydrogenase
LI64_RS11870	COG0395	ABC-type sugar transport system, permease component
LI64_RS11875	COG1175	transmembrane transport
LI64_RS11880	COG1653	transport
LI64_RS11885	COG0366	Alpha amylase catalytic
LI64_RS11895	COG1983	PspC domain protein
LI64_RS11905	COG1842	Phage shock protein A
LI64_RS11910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LI64_RS11925	COG4171	peptide transport system, permease
LI64_RS11935	COG4172	Belongs to the ABC transporter superfamily
LI64_RS11945	COG0251	oxidation-reduction process
LI64_RS11950	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LI64_RS11955	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI64_RS11955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI64_RS11965	COG5001	Diguanylate cyclase
LI64_RS11970	COG1024	Enoyl-CoA hydratase
LI64_RS11980	COG1349	DNA-binding transcription factor activity
LI64_RS11990	COG0023	Translation Initiation Factor
LI64_RS11995	COG0284	orotidine-5'-phosphate decarboxylase activity
LI64_RS12000	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LI64_RS12005	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LI64_RS12010	COG0671	phosphoesterase, PA-phosphatase related
LI64_RS12020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LI64_RS12055	COG0616	signal peptide processing
LI64_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS12065	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LI64_RS12075	COG0009	L-threonylcarbamoyladenylate synthase
LI64_RS12080	COG0613	PHP domain protein
LI64_RS12105	COG0159	tryptophan synthase activity
LI64_RS12110	COG2391	methyltransferase activity
LI64_RS12115	COG0425	Belongs to the sulfur carrier protein TusA family
LI64_RS12125	COG3047	cAMP biosynthetic process
LI64_RS12130	COG0727	PFAM Uncharacterised protein family (UPF0153)
LI64_RS12160	COG2350	Protein conserved in bacteria
LI64_RS12165	COG1280	lysine exporter protein (LysE YggA)
LI64_RS12180	COG3099	Belongs to the UPF0263 family
LI64_RS12185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LI64_RS12190	COG4608	Belongs to the ABC transporter superfamily
LI64_RS12195	COG0444	Belongs to the ABC transporter superfamily
LI64_RS12205	COG0601	transmembrane transport
LI64_RS12215	COG2095	MarC family integral membrane protein
LI64_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS12220	COG1454	alcohol dehydrogenase
LI64_RS12225	COG1435	thymidine kinase activity
LI64_RS12235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LI64_RS12240	COG0745	RESPONSE REGULATOR receiver
LI64_RS12245	COG1752	Esterase of the alpha-beta hydrolase superfamily
LI64_RS12250	COG3012	SEC-C Motif Domain Protein
LI64_RS12255	COG0788	formyltetrahydrofolate deformylase activity
LI64_RS12270	COG2181	nitrate reductase activity
LI64_RS12275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LI64_RS12280	COG1140	nitrate reductase beta subunit
LI64_RS12285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LI64_RS12290	COG2223	nitrite transmembrane transporter activity
LI64_RS12295	COG3850	Histidine kinase
LI64_RS12300	COG2197	response regulator
LI64_RS12305	COG4932	domain protein
LI64_RS12310	COG0243	molybdopterin cofactor binding
LI64_RS12315	COG2146	nitrite reductase [NAD(P)H] activity
LI64_RS12315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LI64_RS12320	COG1116	anion transmembrane transporter activity
LI64_RS12330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LI64_RS12335	COG3707	response regulator
LI64_RS12340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LI64_RS12345	COG0840	transmembrane signaling receptor activity
LI64_RS12355	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LI64_RS12360	COG4572	Cation transport regulator
LI64_RS12365	COG0387	Pfam Sodium calcium exchanger
LI64_RS12370	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LI64_RS12395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LI64_RS12405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LI64_RS12415	COG0659	secondary active sulfate transmembrane transporter activity
LI64_RS12430	COG0193	aminoacyl-tRNA hydrolase activity
LI64_RS12435	COG0012	GTP binding
LI64_RS12485	COG3209	COG3209 Rhs family protein
LI64_RS12510	COG4104	PAAR repeat-containing protein
LI64_RS12535	COG0515	serine threonine protein kinase
LI64_RS12650	COG4977	sequence-specific DNA binding
LI64_RS12655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LI64_RS12670	COG4774	siderophore transport
LI64_RS12680	COG0741	lytic transglycosylase activity
LI64_RS12685	COG1619	proteins homologs of microcin C7 resistance protein MccF
LI64_RS12690	COG3263	regulation of cellular component size
LI64_RS12695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LI64_RS12700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LI64_RS12710	COG2719	SpoVR family
LI64_RS12720	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LI64_RS12730	COG2983	Belongs to the UPF0260 family
LI64_RS12735	COG0179	Fumarylacetoacetate (FAA) hydrolase
LI64_RS12745	COG0850	regulation of cytokinetic process
LI64_RS12750	COG2894	cell division
LI64_RS12755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LI64_RS12760	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LI64_RS12765	COG0318	PFAM AMP-dependent synthetase and ligase
LI64_RS12770	COG3065	identical protein binding
LI64_RS12775	COG1214	PFAM Peptidase M22, glycoprotease
LI64_RS12780	COG1199	ATP-dependent helicase activity
LI64_RS12785	COG0251	oxidation-reduction process
LI64_RS12800	COG0494	nUDIX hydrolase
LI64_RS12805	COG1760	l-serine dehydratase
LI64_RS12810	COG2200	EAL domain
LI64_RS12815	COG1253	flavin adenine dinucleotide binding
LI64_RS12820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS12820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS12825	COG3715	PTS system
LI64_RS12830	COG3716	PTS system mannose fructose sorbose family IID component
LI64_RS12835	COG4811	Protein of unknown function (DUF986)
LI64_RS12840	COG1971	Probably functions as a manganese efflux pump
LI64_RS12845	COG2226	methyltransferase
LI64_RS12850	COG0768	penicillin binding
LI64_RS12880	COG1414	Transcriptional regulator
LI64_RS12885	COG2814	Major facilitator Superfamily
LI64_RS12890	COG0501	Belongs to the peptidase M48B family
LI64_RS12905	COG1956	GAF domain-containing protein
LI64_RS12910	COG2995	paraquat-inducible protein a
LI64_RS12915	COG3008	intermembrane lipid transfer
LI64_RS12920	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LI64_RS12920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LI64_RS12935	COG2990	Protein conserved in bacteria
LI64_RS12950	COG1276	copper resistance
LI64_RS12955	COG2372	response to copper ion
LI64_RS12965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI64_RS12970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LI64_RS12975	COG1770	oligopeptidase
LI64_RS12980	COG2979	Protein of unknown function (DUF533)
LI64_RS13015	COG0800	Aldolase
LI64_RS13020	COG0129	dihydroxy-acid dehydratase activity
LI64_RS13025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LI64_RS13030	COG1737	Transcriptional regulator
LI64_RS13040	COG1560	Kdo2-lipid A biosynthetic process
LI64_RS13045	COG0739	heme binding
LI64_RS13050	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LI64_RS13060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI64_RS13065	COG2255	four-way junction helicase activity
LI64_RS13070	COG0632	four-way junction helicase activity
LI64_RS13085	COG0494	nUDIX hydrolase
LI64_RS13095	COG1335	isochorismatase
LI64_RS13100	COG1801	Protein of unknown function DUF72
LI64_RS13105	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LI64_RS13110	COG2226	methyltransferase
LI64_RS13115	COG0500	methyltransferase
LI64_RS13120	COG3142	Participates in the control of copper homeostasis
LI64_RS13125	COG3102	Protein conserved in bacteria
LI64_RS13130	COG0018	arginyl-trna synthetase
LI64_RS13135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LI64_RS13165	COG0745	RESPONSE REGULATOR receiver
LI64_RS13180	COG0840	transmembrane signaling receptor activity
LI64_RS13215	COG1301	dicarboxylic acid transport
LI64_RS13255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LI64_RS13265	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS13275	COG1879	ABC-type sugar transport system periplasmic component
LI64_RS13285	COG1528	Iron-storage protein
LI64_RS13290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LI64_RS13315	COG1528	Iron-storage protein
LI64_RS13320	COG0814	amino acid
LI64_RS13325	COG3318	Belongs to the UPF0149 family
LI64_RS13325	COG3012	SEC-C Motif Domain Protein
LI64_RS13360	COG0583	DNA-binding transcription factor activity
LI64_RS13390	COG2197	response regulator
LI64_RS13400	COG2197	response regulator
LI64_RS13405	COG1126	abc transporter atp-binding protein
LI64_RS13410	COG0765	amino acid transport
LI64_RS13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS13440	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LI64_RS13445	COG1516	flagellar protein fliS
LI64_RS13455	COG0366	Alpha amylase catalytic
LI64_RS13465	COG1677	Flagellar hook-basal body complex protein FliE
LI64_RS13475	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LI64_RS13485	COG1157	protein secretion by the type III secretion system
LI64_RS13525	COG1987	bacterial-type flagellum assembly
LI64_RS13535	COG2197	response regulator
LI64_RS13560	COG5475	Uncharacterized small protein (DUF2158)
LI64_RS13565	COG2354	Protein conserved in bacteria
LI64_RS13570	COG0697	spore germination
LI64_RS13575	COG3727	T/G mismatch-specific endonuclease activity
LI64_RS13580	COG0270	DNA (cytosine-5-)-methyltransferase activity
LI64_RS13585	COG1418	mRNA catabolic process
LI64_RS13595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI64_RS13605	COG3290	protein histidine kinase activity
LI64_RS13610	COG4565	transcriptional regulatory protein
LI64_RS13630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LI64_RS13630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LI64_RS13655	COG0583	DNA-binding transcription factor activity
LI64_RS13705	COG0737	Belongs to the 5'-nucleotidase family
LI64_RS13725	COG1376	ErfK ybiS ycfS ynhG family protein
LI64_RS13730	COG0477	Major facilitator Superfamily
LI64_RS13735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LI64_RS13745	COG0534	Mate efflux family protein
LI64_RS13760	COG1289	transmembrane transporter activity
LI64_RS13765	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LI64_RS13775	COG2925	Exonuclease
LI64_RS13780	COG0531	amino acid
LI64_RS13785	COG0583	DNA-binding transcription factor activity
LI64_RS13790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI64_RS13795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LI64_RS13805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LI64_RS13810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LI64_RS13810	COG0131	Imidazoleglycerol-phosphate dehydratase
LI64_RS13815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LI64_RS13820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LI64_RS13825	COG0107	imidazoleglycerol-phosphate synthase activity
LI64_RS13830	COG0140	phosphoribosyl-ATP diphosphatase activity
LI64_RS13830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LI64_RS13855	COG1088	dTDP-glucose 4,6-dehydratase activity
LI64_RS13860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LI64_RS13870	COG0438	transferase activity, transferring glycosyl groups
LI64_RS13885	COG0438	transferase activity, transferring glycosyl groups
LI64_RS13895	COG1216	Glycosyl transferase, family 2
LI64_RS13915	COG0438	transferase activity, transferring glycosyl groups
LI64_RS13920	COG2327	Polysaccharide pyruvyl transferase
LI64_RS13925	COG2244	polysaccharide biosynthetic process
LI64_RS13930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LI64_RS13935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LI64_RS13945	COG0297	glycogen (starch) synthase activity
LI64_RS13950	COG1051	belongs to the nudix hydrolase family
LI64_RS13955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI64_RS13960	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LI64_RS13965	COG0110	maltose O-acetyltransferase activity
LI64_RS13970	COG1216	Glycosyl transferase, family 2
LI64_RS13980	COG0438	transferase activity, transferring glycosyl groups
LI64_RS13985	COG1045	serine acetyltransferase
LI64_RS13990	COG0463	Glycosyl transferase, family 2
LI64_RS13995	COG3206	protein involved in exopolysaccharide biosynthesis
LI64_RS13995	COG0489	protein tyrosine kinase activity
LI64_RS14010	COG1253	flavin adenine dinucleotide binding
LI64_RS14015	COG2982	Protein involved in outer membrane biogenesis
LI64_RS14020	COG0717	Belongs to the dCTP deaminase family
LI64_RS14030	COG5002	protein histidine kinase activity
LI64_RS14030	COG5001	Diguanylate cyclase
LI64_RS14030	COG3447	MASE1 domain protein
LI64_RS14035	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LI64_RS14040	COG0443	Heat shock 70 kDa protein
LI64_RS14045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS14050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS14055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS14060	COG0477	Major facilitator Superfamily
LI64_RS14065	COG2205	protein histidine kinase activity
LI64_RS14070	COG0745	RESPONSE REGULATOR receiver
LI64_RS14075	COG0826	peptidase U32
LI64_RS14080	COG1597	lipid kinase activity
LI64_RS14085	COG1830	Aldolase
LI64_RS14090	COG2211	Major facilitator Superfamily
LI64_RS14095	COG1397	ADP-ribosylglycohydrolase
LI64_RS14100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS14105	COG2188	Transcriptional regulator
LI64_RS14110	COG0351	phosphomethylpyrimidine kinase
LI64_RS14115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LI64_RS14185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LI64_RS14190	COG0076	glutamate decarboxylase activity
LI64_RS14195	COG0489	protein tyrosine kinase activity
LI64_RS14195	COG3206	protein involved in exopolysaccharide biosynthesis
LI64_RS14200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LI64_RS14205	COG1596	polysaccharide export
LI64_RS14210	COG5455	response to cobalt ion
LI64_RS14220	COG0489	protein tyrosine kinase activity
LI64_RS14230	COG4807	Protein conserved in bacteria
LI64_RS14240	COG3275	phosphorelay sensor kinase activity
LI64_RS14245	COG0789	Transcriptional regulator
LI64_RS14250	COG1174	glycine betaine transport
LI64_RS14255	COG1125	glycine betaine transport
LI64_RS14260	COG1174	glycine betaine transport
LI64_RS14265	COG1732	Glycine betaine
LI64_RS14270	COG1472	Belongs to the glycosyl hydrolase 3 family
LI64_RS14275	COG0277	FAD linked oxidase domain protein
LI64_RS14285	COG1686	Belongs to the peptidase S11 family
LI64_RS14295	COG0586	Pfam SNARE associated Golgi protein
LI64_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS14305	COG1538	Outer membrane efflux protein
LI64_RS14310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LI64_RS14320	COG1346	cytolysis
LI64_RS14325	COG0295	cytidine deaminase activity
LI64_RS14330	COG2949	membrane
LI64_RS14340	COG1129	ABC transporter
LI64_RS14355	COG2311	Membrane
LI64_RS14365	COG0477	Major facilitator Superfamily
LI64_RS14370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LI64_RS14375	COG4771	TonB-dependent receptor
LI64_RS14380	COG0833	amino acid
LI64_RS14385	COG0583	DNA-binding transcription factor activity
LI64_RS14390	COG2855	membrane
LI64_RS14395	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LI64_RS14400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS14400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LI64_RS14400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI64_RS14405	COG1105	Belongs to the carbohydrate kinase PfkB family
LI64_RS14430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LI64_RS14435	COG1312	Catalyzes the dehydration of D-mannonate
LI64_RS14440	COG0246	Mannitol dehydrogenase
LI64_RS14445	COG0523	cobalamin synthesis protein
LI64_RS14450	COG0671	phosphoesterase, PA-phosphatase related
LI64_RS14455	COG0791	NLP P60 protein
LI64_RS14460	COG2200	EAL domain
LI64_RS14465	COG4166	transmembrane transport
LI64_RS14470	COG4174	ABC transporter (Permease)
LI64_RS14475	COG4239	(ABC) transporter, permease
LI64_RS14480	COG4172	Belongs to the ABC transporter superfamily
LI64_RS14490	COG2814	Major facilitator Superfamily
LI64_RS14495	COG1187	pseudouridine synthase activity
LI64_RS14500	COG1061	Type III restriction enzyme res subunit
LI64_RS14510	COG3081	Nucleoid-associated protein
LI64_RS14515	COG3082	Protein of unknown function (DUF1414)
LI64_RS14530	COG3182	Iron-regulated membrane protein
LI64_RS14540	COG0579	oxidoreductase
LI64_RS14545	COG0659	secondary active sulfate transmembrane transporter activity
LI64_RS14550	COG2239	Acts as a magnesium transporter
LI64_RS14555	COG4615	Cyclic peptide transporter
LI64_RS14565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LI64_RS14565	COG2169	Transcriptional regulator
LI64_RS14575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI64_RS14580	COG2198	Histidine kinase
LI64_RS14580	COG0642	Histidine kinase
LI64_RS14600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LI64_RS14615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI64_RS14620	COG0584	glycerophosphoryl diester phosphodiesterase
LI64_RS14625	COG2271	Major facilitator Superfamily
LI64_RS14630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LI64_RS14635	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LI64_RS14640	COG0247	lactate metabolic process
LI64_RS14655	COG0642	Histidine kinase
LI64_RS14685	COG1441	menaquinone biosynthetic process
LI64_RS14695	COG0596	Alpha beta hydrolase
LI64_RS14700	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LI64_RS14705	COG1169	isochorismate synthase
LI64_RS14710	COG4575	ribosome binding
LI64_RS14715	COG2153	protein acetylation
LI64_RS14720	COG1234	tRNA 3'-trailer cleavage
LI64_RS14725	COG0784	Response regulator, receiver
LI64_RS14725	COG0835	chemotaxis
LI64_RS14730	COG1007	ATP synthesis coupled electron transport
LI64_RS14735	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI64_RS14740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LI64_RS14745	COG0713	ATP synthesis coupled electron transport
LI64_RS14750	COG0839	Belongs to the complex I subunit 6 family
LI64_RS14760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LI64_RS14790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI64_RS14795	COG0583	DNA-binding transcription factor activity
LI64_RS14800	COG0436	Aminotransferase
LI64_RS14810	COG0471	metal ion transport
LI64_RS14810	COG0490	domain, Protein
LI64_RS14815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI64_RS14840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LI64_RS14845	COG3959	Transketolase, thiamine diphosphate binding domain
LI64_RS14850	COG3037	sugar-specific permease SgaT UlaA
LI64_RS14860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS14865	COG1609	Transcriptional regulator
LI64_RS14875	COG0622	Phosphoesterase
LI64_RS14880	COG0625	glutathione transferase activity
LI64_RS14885	COG0625	glutathione transferase activity
LI64_RS14890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LI64_RS14895	COG1090	epimerase
LI64_RS14900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI64_RS14905	COG4598	ABC transporter
LI64_RS14910	COG4160	amino acid transport
LI64_RS14920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI64_RS14930	COG0163	prenyltransferase activity
LI64_RS14935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LI64_RS14940	COG1286	toxin biosynthetic process
LI64_RS14945	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LI64_RS14950	COG0285	dihydrofolate synthase activity
LI64_RS14960	COG0586	Pfam SNARE associated Golgi protein
LI64_RS14965	COG0101	tRNA pseudouridine synthase activity
LI64_RS14970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LI64_RS14975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI64_RS14990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI64_RS14995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LI64_RS14995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LI64_RS15005	COG3101	peptidyl-lysine hydroxylation
LI64_RS15010	COG0730	response to heat
LI64_RS15020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LI64_RS15030	COG2840	Smr protein MutS2
LI64_RS15035	COG2062	phosphohistidine phosphatase, SixA
LI64_RS15040	COG1024	Enoyl-CoA hydratase
LI64_RS15040	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI64_RS15050	COG3691	Protein conserved in bacteria
LI64_RS15055	COG2067	long-chain fatty acid transport protein
LI64_RS15065	COG2116	formate transmembrane transporter activity
LI64_RS15075	COG1560	Kdo2-lipid A biosynthetic process
LI64_RS15085	COG0436	Aminotransferase
LI64_RS15090	COG3275	phosphorelay sensor kinase activity
LI64_RS15095	COG3279	Response regulator of the LytR AlgR family
LI64_RS15100	COG0837	glucose binding
LI64_RS15110	COG3961	Belongs to the TPP enzyme family
LI64_RS15115	COG0667	Aldo Keto reductase
LI64_RS15125	COG1914	H( )-stimulated, divalent metal cation uptake system
LI64_RS15130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LI64_RS15135	COG2200	EAL domain
LI64_RS15135	COG2199	diguanylate cyclase activity
LI64_RS15150	COG3415	Transposase
LI64_RS15155	COG3415	Transposase
LI64_RS15160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LI64_RS15190	COG0583	DNA-binding transcription factor activity
LI64_RS15195	COG0385	Bile acid
LI64_RS15200	COG3530	Putative quorum-sensing-regulated virulence factor
LI64_RS15205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LI64_RS15210	COG3115	cell septum assembly
LI64_RS15225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS15250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LI64_RS15255	COG4208	sulfate ABC transporter
LI64_RS15260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LI64_RS15265	COG4150	thiosulfate binding
LI64_RS15270	COG2837	iron assimilation
LI64_RS15290	COG0860	N-Acetylmuramoyl-L-alanine amidase
LI64_RS15295	COG0408	coproporphyrinogen oxidase activity
LI64_RS15310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LI64_RS15315	COG5342	invasion associated locus B
LI64_RS15320	COG0494	nUDIX hydrolase
LI64_RS15325	COG0493	'glutamate synthase
LI64_RS15325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI64_RS15335	COG3850	Histidine kinase
LI64_RS15340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS15345	COG1393	Belongs to the ArsC family
LI64_RS15350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LI64_RS15360	COG0400	carboxylic ester hydrolase activity
LI64_RS15370	COG2321	neutral zinc metallopeptidase
LI64_RS15375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LI64_RS15380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LI64_RS15390	COG2716	regulation of RNA biosynthetic process
LI64_RS15395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LI64_RS15400	COG0628	permease
LI64_RS15405	COG4783	chaperone-mediated protein folding
LI64_RS15410	COG1393	Belongs to the ArsC family
LI64_RS15425	COG1446	asparaginase
LI64_RS15430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI64_RS15440	COG2233	PERMEase
LI64_RS15445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LI64_RS15450	COG2723	6-phospho-beta-galactosidase activity
LI64_RS15460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LI64_RS15475	COG2200	EAL domain
LI64_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS15500	COG3713	MltA-interacting MipA family protein
LI64_RS15505	COG0745	RESPONSE REGULATOR receiver
LI64_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS15530	COG3708	Transcriptional regulator
LI64_RS15530	COG2207	Transcriptional regulator
LI64_RS15560	COG0582	viral genome integration into host DNA
LI64_RS15575	COG0517	IMP dehydrogenase activity
LI64_RS15575	COG0516	GMP reductase activity
LI64_RS15580	COG1570	exodeoxyribonuclease VII activity
LI64_RS15595	COG1645	bacterial-type flagellum-dependent swarming motility
LI64_RS15630	COG1160	GTP binding
LI64_RS15640	COG2976	Protein conserved in bacteria
LI64_RS15645	COG0124	histidyl-tRNA synthetase
LI64_RS15650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LI64_RS15660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LI64_RS15680	COG0437	4 iron, 4 sulfur cluster binding
LI64_RS15685	COG0243	molybdopterin cofactor binding
LI64_RS15690	COG4953	penicillin-binding protein 1C
LI64_RS15695	COG2373	Large extracellular alpha-helical protein
LI64_RS15700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS15700	COG1263	PTS System
LI64_RS15700	COG2190	(PTS) system
LI64_RS15710	COG2897	thiosulfate sulfurtransferase activity
LI64_RS15715	COG1737	Transcriptional regulator
LI64_RS15725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI64_RS15730	COG2975	iron-sulfur cluster assembly
LI64_RS15735	COG0633	Ferredoxin
LI64_RS15740	COG0443	Heat shock 70 kDa protein
LI64_RS15745	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LI64_RS15750	COG0316	Belongs to the HesB IscA family
LI64_RS15755	COG0822	iron-sulfur transferase activity
LI64_RS15760	COG1104	cysteine desulfurase activity
LI64_RS15780	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LI64_RS15790	COG3711	transcriptional antiterminator
LI64_RS15795	COG2814	Major facilitator Superfamily
LI64_RS15800	COG2259	Doxx family
LI64_RS15815	COG1017	nitric oxide dioxygenase activity
LI64_RS15815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI64_RS15820	COG0347	Belongs to the P(II) protein family
LI64_RS15825	COG2204	response regulator
LI64_RS15830	COG3170	Tfp pilus assembly protein FimV
LI64_RS15835	COG2205	protein histidine kinase activity
LI64_RS15840	COG0047	phosphoribosylformylglycinamidine synthase activity
LI64_RS15840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LI64_RS15845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LI64_RS15855	COG0560	Phosphoserine phosphatase
LI64_RS15860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS15860	COG1263	PTS System
LI64_RS15865	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LI64_RS15870	COG1737	Transcriptional regulator
LI64_RS15875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI64_RS15885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LI64_RS15890	COG1381	Involved in DNA repair and RecF pathway recombination
LI64_RS15895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LI64_RS15905	COG0681	Belongs to the peptidase S26 family
LI64_RS15915	COG3086	response to oxidative stress
LI64_RS15925	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LI64_RS15935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LI64_RS15940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LI64_RS15945	COG0513	Belongs to the DEAD box helicase family
LI64_RS15950	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LI64_RS15955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LI64_RS15960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI64_RS15965	COG3118	belongs to the thioredoxin family
LI64_RS15970	COG3148	PFAM DTW domain containing protein
LI64_RS15975	COG1042	CoA-binding domain protein
LI64_RS15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI64_RS15975	COG0045	succinate-CoA ligase (ADP-forming) activity
LI64_RS15980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LI64_RS15985	COG5544	Lipoprotein
LI64_RS15990	COG0477	Major facilitator Superfamily
LI64_RS16020	COG0542	response to heat
LI64_RS16030	COG0564	pseudouridine synthase activity
LI64_RS16035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS16040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LI64_RS16045	COG1605	Chorismate mutase
LI64_RS16045	COG0077	Prephenate dehydratase
LI64_RS16055	COG1605	Chorismate mutase
LI64_RS16055	COG0287	Prephenate dehydrogenase
LI64_RS16060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI64_RS16070	COG2199	diguanylate cyclase activity
LI64_RS16075	COG2885	chlorophyll binding
LI64_RS16095	COG0336	Belongs to the RNA methyltransferase TrmD family
LI64_RS16100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LI64_RS16110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LI64_RS16115	COG4137	Cytochrome C assembly protein
LI64_RS16120	COG4536	flavin adenine dinucleotide binding
LI64_RS16125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LI64_RS16135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LI64_RS16140	COG0497	DNA recombination
LI64_RS16155	COG2867	negative regulation of translational initiation
LI64_RS16165	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LI64_RS16170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LI64_RS16180	COG1263	PTS System
LI64_RS16180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS16180	COG2190	(PTS) system
LI64_RS16190	COG1401	restriction endodeoxyribonuclease activity
LI64_RS16190	COG1401	restriction endodeoxyribonuclease activity
LI64_RS16200	COG2826	transposase and inactivated derivatives, IS30 family
LI64_RS16210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS16215	COG2963	transposase activity
LI64_RS16220	COG2801	Transposase and inactivated derivatives
LI64_RS16240	COG0401	homolog of Blt101
LI64_RS16245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LI64_RS16270	COG4575	ribosome binding
LI64_RS16280	COG1780	Probably involved in ribonucleotide reductase function
LI64_RS16295	COG4175	Glycine betaine
LI64_RS16300	COG4176	ABC-type proline glycine betaine transport system permease component
LI64_RS16310	COG2814	Major facilitator Superfamily
LI64_RS16315	COG1846	Transcriptional regulator
LI64_RS16320	COG1566	PFAM secretion protein HlyD family protein
LI64_RS16325	COG2814	Major facilitator Superfamily
LI64_RS16330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LI64_RS16345	COG2918	glutathione biosynthetic process
LI64_RS16350	COG1238	metal cluster binding
LI64_RS16355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI64_RS16385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LI64_RS16390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LI64_RS16405	COG1546	Belongs to the CinA family
LI64_RS16415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI64_RS16425	COG2951	lytic endotransglycosylase activity
LI64_RS16430	COG0517	IMP dehydrogenase activity
LI64_RS16430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LI64_RS16435	COG3604	Transcriptional regulator
LI64_RS16440	COG1773	rubredoxin
LI64_RS16440	COG0426	domain, Protein
LI64_RS16445	COG0446	pyridine nucleotide-disulphide oxidoreductase
LI64_RS16450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LI64_RS16455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LI64_RS16460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI64_RS16465	COG1609	Transcriptional regulator
LI64_RS16470	COG1263	PTS System
LI64_RS16470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS16475	COG2723	6-phospho-beta-galactosidase activity
LI64_RS16480	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LI64_RS16490	COG3260	NADH ubiquinone oxidoreductase 20
LI64_RS16495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI64_RS16500	COG3261	NADH dehydrogenase
LI64_RS16500	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LI64_RS16505	COG0650	Formate hydrogenlyase subunit 4
LI64_RS16510	COG0651	ATP synthesis coupled electron transport
LI64_RS16515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI64_RS16525	COG0375	protein maturation
LI64_RS16530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LI64_RS16535	COG0298	carbon dioxide binding
LI64_RS16540	COG0409	Hydrogenase expression formation protein
LI64_RS16545	COG0309	Hydrogenase expression formation protein (HypE)
LI64_RS16560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS16565	COG1120	ATPase activity
LI64_RS16655	COG0084	hydrolase, TatD family'
LI64_RS16690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LI64_RS16695	COG0163	prenyltransferase activity
LI64_RS16710	COG0477	Major facilitator Superfamily
LI64_RS16725	COG1388	LysM domain
LI64_RS16725	COG4942	peptidase
LI64_RS16740	COG0585	pseudouridine synthase activity
LI64_RS16750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LI64_RS16755	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LI64_RS16765	COG0529	Catalyzes the synthesis of activated sulfate
LI64_RS16785	COG2234	aminopeptidase activity
LI64_RS16800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LI64_RS16805	COG0720	synthase
LI64_RS16815	COG1473	amidohydrolase
LI64_RS16825	COG0602	queuosine metabolic process
LI64_RS16830	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LI64_RS16835	COG2190	(PTS) system
LI64_RS16835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI64_RS16835	COG1263	PTS System
LI64_RS16840	COG1737	Transcriptional regulator
LI64_RS16855	COG3956	TIGRFAM MazG family protein
LI64_RS16860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LI64_RS16865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI64_RS16870	COG3850	Histidine kinase
LI64_RS16870	COG4999	Histidine kinase
LI64_RS16870	COG2205	protein histidine kinase activity
LI64_RS16870	COG3437	response regulator, receiver
LI64_RS16875	COG1929	Belongs to the glycerate kinase type-1 family
LI64_RS16880	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS16885	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS16890	COG2271	Major facilitator Superfamily
LI64_RS16895	COG0716	FMN binding
LI64_RS16900	COG0564	pseudouridine synthase activity
LI64_RS16905	COG3098	single-species biofilm formation
LI64_RS16920	COG1611	Belongs to the LOG family
LI64_RS16925	COG0814	amino acid
LI64_RS16930	COG1760	l-serine dehydratase
LI64_RS16940	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LI64_RS16945	COG2363	Small membrane protein
LI64_RS16950	COG0583	DNA-binding transcription factor activity
LI64_RS16960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LI64_RS16965	COG2166	iron-sulfur cluster assembly
LI64_RS16970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LI64_RS16975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LI64_RS16995	COG0860	N-Acetylmuramoyl-L-alanine amidase
LI64_RS17000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LI64_RS17000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LI64_RS17005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LI64_RS17010	COG1074	ATP-dependent DNA helicase activity
LI64_RS17020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LI64_RS17025	COG4967	type IV pilus modification protein PilV
LI64_RS17035	COG4795	General secretion pathway protein
LI64_RS17040	COG2165	general secretion pathway protein
LI64_RS17045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LI64_RS17050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LI64_RS17060	COG0494	nUDIX hydrolase
LI64_RS17065	COG3066	DNA modification
LI64_RS17075	COG0667	Aldo Keto reductase
LI64_RS17080	COG0477	Major facilitator Superfamily
LI64_RS17085	COG0318	PFAM AMP-dependent synthetase and ligase
LI64_RS17085	COG0204	Acyl-transferase
LI64_RS17090	COG1609	Transcriptional regulator
LI64_RS17100	COG2186	Transcriptional regulator
LI64_RS17105	COG2723	6-phospho-beta-galactosidase activity
LI64_RS17110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI64_RS17115	COG1609	Transcriptional regulator
LI64_RS17125	COG0583	DNA-binding transcription factor activity
LI64_RS17130	COG1794	racemase activity, acting on amino acids and derivatives
LI64_RS17140	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LI64_RS17145	COG1175	transmembrane transport
LI64_RS17150	COG0395	ABC-type sugar transport system, permease component
LI64_RS17155	COG3842	ATPase activity
LI64_RS17165	COG2814	Major facilitator Superfamily
LI64_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS17175	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LI64_RS17180	COG0823	Involved in the tonB-independent uptake of proteins
LI64_RS17185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI64_RS17190	COG0183	Belongs to the thiolase family
LI64_RS17205	COG0814	amino acid
LI64_RS17210	COG2388	GCN5-related N-acetyl-transferase
LI64_RS17215	COG3592	Divergent 4Fe-4S mono-cluster
LI64_RS17220	COG3729	General stress protein
LI64_RS17225	COG3685	Protein conserved in bacteria
LI64_RS17230	COG3685	Protein conserved in bacteria
LI64_RS17235	COG3546	catalase activity
LI64_RS17240	COG1271	oxidase subunit
LI64_RS17245	COG1294	oxidase, subunit
LI64_RS17260	COG1546	Belongs to the CinA family
LI64_RS17275	COG3111	PFAM Bacterial OB fold (BOF) protein
LI64_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS17285	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LI64_RS17305	COG2067	long-chain fatty acid transport protein
LI64_RS17325	COG4942	peptidase
LI64_RS17330	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LI64_RS17335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LI64_RS17350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LI64_RS17360	COG4974	Belongs to the 'phage' integrase family
LI64_RS17375	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LI64_RS17380	COG0354	folic acid binding
LI64_RS17385	COG1272	protein, Hemolysin III
LI64_RS17390	COG1737	Transcriptional regulator
LI64_RS17395	COG2723	6-phospho-beta-galactosidase activity
LI64_RS17415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LI64_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS17425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LI64_RS17425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LI64_RS17435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LI64_RS17440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI64_RS17445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI64_RS17450	COG0006	proline dipeptidase activity
LI64_RS17460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LI64_RS17465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LI64_RS17470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI64_RS17475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LI64_RS17480	COG0583	DNA-binding transcription factor activity
LI64_RS17485	COG2968	Membrane
LI64_RS17490	COG1279	arginine transmembrane transporter activity
LI64_RS17495	COG0668	transmembrane transport
LI64_RS17500	COG0191	fructose-bisphosphate aldolase activity
LI64_RS17505	COG0126	phosphoglycerate kinase activity
LI64_RS17510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LI64_RS17515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LI64_RS17520	COG0501	Belongs to the peptidase M48B family
LI64_RS17535	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LI64_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS17545	COG2267	carboxylic ester hydrolase activity
LI64_RS17570	COG1414	Transcriptional regulator
LI64_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS17590	COG2146	nitrite reductase [NAD(P)H] activity
LI64_RS17595	COG0010	Belongs to the arginase family
LI64_RS17600	COG1166	arginine decarboxylase activity
LI64_RS17650	COG2814	Major facilitator Superfamily
LI64_RS17655	COG3091	SprT-like family
LI64_RS17660	COG2356	endonuclease I
LI64_RS17665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LI64_RS17685	COG2805	Type II/IV secretion system protein
LI64_RS17690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LI64_RS17695	COG0762	integral membrane protein
LI64_RS17700	COG1872	DUF167
LI64_RS17710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LI64_RS17715	COG2852	Protein conserved in bacteria
LI64_RS17725	COG3171	Protein conserved in bacteria
LI64_RS17735	COG1194	a g-specific adenine glycosylase
LI64_RS17745	COG0741	lytic transglycosylase activity
LI64_RS17750	COG2211	Major facilitator Superfamily
LI64_RS17755	COG1982	Orn Lys Arg decarboxylase major
LI64_RS17760	COG1811	Na channel or pump
LI64_RS17785	COG1649	PFAM Uncharacterised BCR, COG1649
LI64_RS17785	COG0726	polysaccharide deacetylase
LI64_RS17790	COG1215	transferase activity, transferring glycosyl groups
LI64_RS17800	COG0754	glutathionylspermidine amidase activity
LI64_RS17805	COG0625	glutathione transferase activity
LI64_RS17815	COG1349	DNA-binding transcription factor activity
LI64_RS17820	COG0840	transmembrane signaling receptor activity
LI64_RS17825	COG0667	Aldo Keto reductase
LI64_RS17830	COG2862	Uncharacterized protein family, UPF0114
LI64_RS17850	COG0848	biopolymer transport protein
LI64_RS17860	COG0626	cystathionine gamma-synthase activity
LI64_RS17865	COG0586	Pfam SNARE associated Golgi protein
LI64_RS17870	COG2207	Transcriptional regulator
LI64_RS17875	COG1979	alcohol dehydrogenase
LI64_RS17885	COG1032	radical SAM domain protein
LI64_RS17955	COG3436	PFAM IS66 Orf2 family protein
LI64_RS17975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LI64_RS17990	COG1595	DNA-templated transcription, initiation
LI64_RS17995	COG3712	iron ion homeostasis
LI64_RS18000	COG4772	TonB-dependent receptor
LI64_RS18005	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LI64_RS18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS18015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI64_RS18020	COG1120	ATPase activity
LI64_RS18025	COG3436	PFAM IS66 Orf2 family protein
LI64_RS18055	COG0640	Transcriptional regulator
LI64_RS18060	COG0431	NADPH-dependent FMN reductase
LI64_RS18100	COG1609	Transcriptional regulator
LI64_RS18110	COG2223	nitrite transmembrane transporter activity
LI64_RS18115	COG0110	maltose O-acetyltransferase activity
LI64_RS18135	COG2801	Transposase and inactivated derivatives
LI64_RS18180	COG1032	radical SAM domain protein
LI64_RS18185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LI64_RS18205	COG3111	PFAM Bacterial OB fold (BOF) protein
LI64_RS18220	COG2249	NAD(P)H dehydrogenase (quinone) activity
LI64_RS18225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LI64_RS18230	COG1652	LysM domain
LI64_RS18235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LI64_RS18240	COG2211	Major facilitator Superfamily
LI64_RS18255	COG0187	DNA topoisomerase II activity
LI64_RS18260	COG3150	esterase
LI64_RS18265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LI64_RS18270	COG3151	Protein conserved in bacteria
LI64_RS18275	COG0494	nUDIX hydrolase
LI64_RS18290	COG0754	glutathionylspermidine amidase activity
LI64_RS18295	COG3384	dioxygenase
LI64_RS18305	COG3539	Fimbrial protein
LI64_RS18310	COG3188	usher protein
LI64_RS18315	COG3121	Chaperone
LI64_RS18320	COG3539	Fimbrial protein
LI64_RS18325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LI64_RS18335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LI64_RS18335	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LI64_RS18345	COG3025	triphosphatase activity
LI64_RS18350	COG4991	sh3 domain protein
LI64_RS18355	COG0617	tRNA 3'-terminal CCA addition
LI64_RS18365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LI64_RS18375	COG0829	nickel cation binding
LI64_RS18380	COG0831	urea catabolic process
LI64_RS18385	COG0832	Belongs to the urease beta subunit family
LI64_RS18390	COG0804	urea catabolic process
LI64_RS18395	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LI64_RS18405	COG0830	nickel cation binding
LI64_RS18410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LI64_RS18420	COG2197	response regulator
LI64_RS18430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LI64_RS18435	COG0358	DNA primase activity
LI64_RS18445	COG3663	DNA glycosylase
LI64_RS18470	COG1802	Transcriptional regulator
LI64_RS18470	COG4626	Terminase
LI64_RS18545	COG3561	AntA/AntB antirepressor
LI64_RS18555	COG0582	viral genome integration into host DNA
LI64_RS18565	COG2963	transposase activity
LI64_RS18580	COG3210	domain, Protein
LI64_RS18595	COG3210	domain, Protein
LI64_RS18610	COG2375	cellular response to nickel ion
LI64_RS18615	COG1695	Transcriptional regulator
LI64_RS18620	COG0840	transmembrane signaling receptor activity
LI64_RS18625	COG0840	transmembrane signaling receptor activity
LI64_RS18630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LI64_RS18645	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LI64_RS18650	COG1830	Aldolase
LI64_RS18655	COG1879	ABC-type sugar transport system periplasmic component
LI64_RS18660	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS18665	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS18670	COG1129	ABC transporter
LI64_RS18675	COG2390	Transcriptional regulator
LI64_RS18680	COG1070	Carbohydrate kinase
LI64_RS18685	COG0446	pyridine nucleotide-disulphide oxidoreductase
LI64_RS18685	COG1902	pentaerythritol trinitrate reductase activity
LI64_RS18695	COG1451	nucleotide metabolic process
LI64_RS18700	COG0673	inositol 2-dehydrogenase activity
LI64_RS18705	COG0861	Integral membrane protein TerC family
LI64_RS18715	COG2721	sulfolactate sulfo-lyase activity
LI64_RS18725	COG2271	Major facilitator Superfamily
LI64_RS18730	COG2186	Transcriptional regulator
LI64_RS18735	COG0586	Pfam SNARE associated Golgi protein
LI64_RS18745	COG1422	Protein of unknown function (DUF1090)
LI64_RS18750	COG4575	ribosome binding
LI64_RS18755	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LI64_RS18765	COG2259	Doxx family
LI64_RS18770	COG0435	Glutathione S-transferase
LI64_RS18775	COG3152	Membrane
LI64_RS18780	COG0583	DNA-binding transcription factor activity
LI64_RS18785	COG1741	Belongs to the pirin family
LI64_RS18795	COG0814	amino acid
LI64_RS18800	COG1882	Formate acetyltransferase
LI64_RS18805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LI64_RS18810	COG0814	amino acid
LI64_RS18815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LI64_RS18820	COG0583	DNA-binding transcription factor activity
LI64_RS18825	COG1929	Belongs to the glycerate kinase type-1 family
LI64_RS18830	COG2084	Dehydrogenase
LI64_RS18840	COG2721	sulfolactate sulfo-lyase activity
LI64_RS18855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS18860	COG3414	Phosphotransferase system galactitol-specific IIB component
LI64_RS18865	COG3775	system Galactitol-specific IIC component
LI64_RS18870	COG1063	alcohol dehydrogenase
LI64_RS18885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LI64_RS18890	COG3107	peptidoglycan biosynthetic process
LI64_RS18895	COG0792	nuclease activity
LI64_RS18900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LI64_RS18905	COG2823	Periplasmic or secreted lipoprotein
LI64_RS18910	COG0701	Predicted permease
LI64_RS18915	COG0702	epimerase
LI64_RS18920	COG0693	protein deglycase activity
LI64_RS18925	COG3787	Belongs to the UPF0306 family
LI64_RS18930	COG2827	Endonuclease containing a URI domain
LI64_RS18935	COG3153	acetyltransferase
LI64_RS18940	COG3154	lipid carrier protein
LI64_RS18945	COG0826	peptidase U32
LI64_RS18950	COG0826	peptidase U32
LI64_RS18955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI64_RS18960	COG3415	Transposase
LI64_RS18960	COG2801	Transposase and inactivated derivatives
LI64_RS18965	COG0814	amino acid
LI64_RS18970	COG0513	Belongs to the DEAD box helicase family
LI64_RS18985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LI64_RS18990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LI64_RS18995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LI64_RS19000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LI64_RS19020	COG0137	argininosuccinate synthase activity
LI64_RS19030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LI64_RS19035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LI64_RS19040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LI64_RS19050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LI64_RS19055	COG1534	Rna-binding protein
LI64_RS19065	COG2027	D-alanyl-D-alanine carboxypeptidase
LI64_RS19070	COG0745	RESPONSE REGULATOR receiver
LI64_RS19075	COG0642	Histidine kinase
LI64_RS19080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LI64_RS19085	COG0697	spore germination
LI64_RS19095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LI64_RS19100	COG0142	geranyltranstransferase activity
LI64_RS19105	COG3423	Transcriptional regulator
LI64_RS19110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LI64_RS19115	COG5007	Belongs to the BolA IbaG family
LI64_RS19120	COG3113	response to antibiotic
LI64_RS19125	COG2854	intermembrane phospholipid transfer
LI64_RS19130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LI64_RS19135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LI64_RS19140	COG1127	ABC transporter
LI64_RS19145	COG0530	calcium, potassium:sodium antiporter activity
LI64_RS19155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LI64_RS19160	COG3117	lipopolysaccharide transmembrane transporter activity
LI64_RS19165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LI64_RS19170	COG1137	ATPase activity
LI64_RS19175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LI64_RS19195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS19205	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LI64_RS19210	COG0784	Response regulator, receiver
LI64_RS19210	COG2198	Histidine kinase
LI64_RS19210	COG5002	protein histidine kinase activity
LI64_RS19215	COG0795	lipopolysaccharide-transporting ATPase activity
LI64_RS19220	COG0795	lipopolysaccharide-transporting ATPase activity
LI64_RS19225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI64_RS19230	COG2927	DNA polymerase III (CHI subunit)
LI64_RS19240	COG0456	acetyltransferase
LI64_RS19245	COG1064	alcohol dehydrogenase
LI64_RS19255	COG0433	COG0433 Predicted ATPase
LI64_RS19260	COG1242	4 iron, 4 sulfur cluster binding
LI64_RS19265	COG0069	glutamate synthase activity
LI64_RS19265	COG0070	glutamate synthase
LI64_RS19265	COG0067	glutamate synthase
LI64_RS19270	COG0493	'glutamate synthase
LI64_RS19280	COG3188	usher protein
LI64_RS19285	COG3121	Chaperone
LI64_RS19290	COG2969	positive regulation of protein catabolic process
LI64_RS19295	COG0625	glutathione transferase activity
LI64_RS19300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LI64_RS19310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LI64_RS19315	COG3105	Protein conserved in bacteria
LI64_RS19320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LI64_RS19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LI64_RS19335	COG1438	arginine binding
LI64_RS19345	COG2732	(Barnase) inhibitor
LI64_RS19350	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS19355	COG1289	transmembrane transporter activity
LI64_RS19370	COG0583	DNA-binding transcription factor activity
LI64_RS19375	COG0312	modulator of DNA gyrase
LI64_RS19380	COG3164	Protein of unknown function
LI64_RS19395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LI64_RS19400	COG1792	Involved in formation and maintenance of cell shape
LI64_RS19405	COG1077	Cell shape determining protein MreB Mrl
LI64_RS19410	COG2199	diguanylate cyclase activity
LI64_RS19410	COG2200	EAL domain
LI64_RS19415	COG0604	alcohol dehydrogenase
LI64_RS19425	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LI64_RS19430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LI64_RS19435	COG0511	ligase activity, forming carbon-carbon bonds
LI64_RS19440	COG0439	Biotin carboxylase
LI64_RS19445	COG3924	membrane
LI64_RS19450	COG4145	pantothenate transmembrane transporter activity
LI64_RS19485	COG1309	transcriptional regulator
LI64_RS19490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS19495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI64_RS19535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI64_RS19550	COG0009	L-threonylcarbamoyladenylate synthase
LI64_RS19555	COG0551	DNA topoisomerase type I activity
LI64_RS19560	COG2922	Belongs to the Smg family
LI64_RS19565	COG0758	DNA mediated transformation
LI64_RS19570	COG0242	peptide deformylase activity
LI64_RS19575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LI64_RS19580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LI64_RS19580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LI64_RS19590	COG1970	mechanosensitive ion channel activity
LI64_RS19595	COG3036	rescue of stalled ribosome
LI64_RS19600	COG0789	Transcriptional regulator
LI64_RS19615	COG0202	RNA polymerase activity
LI64_RS19625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LI64_RS19640	COG0201	protein transport
LI64_RS19650	COG1841	ribosomal large subunit assembly
LI64_RS19665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LI64_RS19670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LI64_RS19700	COG0255	Belongs to the universal ribosomal protein uL29 family
LI64_RS19705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LI64_RS19745	COG0051	transcription antitermination factor activity, RNA binding
LI64_RS19785	COG2168	tRNA wobble position uridine thiolation
LI64_RS19790	COG2923	Belongs to the DsrF TusC family
LI64_RS19795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LI64_RS19800	COG2964	Protein conserved in bacteria
LI64_RS19805	COG0545	Peptidyl-prolyl cis-trans isomerase
LI64_RS19815	COG1047	Peptidyl-prolyl cis-trans
LI64_RS19820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LI64_RS19825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI64_RS19825	COG0475	glutathione-regulated potassium exporter activity
LI64_RS19830	COG2249	NAD(P)H dehydrogenase (quinone) activity
LI64_RS19835	COG0488	(ABC) transporter
LI64_RS19845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LI64_RS19855	COG0679	Auxin Efflux Carrier
LI64_RS19890	COG0429	hydrolase of the alpha beta-hydrolase fold
LI64_RS19895	COG3089	Belongs to the UPF0270 family
LI64_RS19900	COG3954	Phosphoribulokinase
LI64_RS19905	COG1765	OsmC-like protein
LI64_RS19915	COG1289	transmembrane transporter activity
LI64_RS19920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LI64_RS19930	COG2184	nucleotidyltransferase activity
LI64_RS19940	COG0738	Major facilitator superfamily
LI64_RS19950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LI64_RS19960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LI64_RS19960	COG1648	precorrin-2 dehydrogenase activity
LI64_RS19970	COG0180	Tryptophanyl-tRNA synthetase
LI64_RS19980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LI64_RS19985	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LI64_RS19990	COG3266	domain, Protein
LI64_RS19995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LI64_RS20000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI64_RS20010	COG4796	Type ii and iii secretion system protein
LI64_RS20030	COG4972	Pilus assembly protein
LI64_RS20035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LI64_RS20040	COG0494	nUDIX hydrolase
LI64_RS20055	COG1011	Hydrolase
LI64_RS20060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LI64_RS20065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LI64_RS20070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LI64_RS20085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LI64_RS20090	COG2183	response to ionizing radiation
LI64_RS20095	COG1918	ferrous iron import across plasma membrane
LI64_RS20115	COG1040	competence protein
LI64_RS20125	COG2610	gluconate transmembrane transporter activity
LI64_RS20130	COG1640	4-alpha-glucanotransferase
LI64_RS20135	COG0058	SHG alpha-glucan phosphorylase activity
LI64_RS20140	COG2909	trisaccharide binding
LI64_RS20145	COG1349	DNA-binding transcription factor activity
LI64_RS20150	COG0705	Rhomboid family
LI64_RS20155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LI64_RS20165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LI64_RS20170	COG0058	SHG alpha-glucan phosphorylase activity
LI64_RS20175	COG0297	glycogen (starch) synthase activity
LI64_RS20180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LI64_RS20185	COG1523	belongs to the glycosyl hydrolase 13 family
LI64_RS20190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LI64_RS20195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LI64_RS20205	COG2095	MarC family integral membrane protein
LI64_RS20210	COG2610	gluconate transmembrane transporter activity
LI64_RS20215	COG3265	gluconokinase activity
LI64_RS20220	COG1609	Transcriptional regulator
LI64_RS20225	COG1741	Belongs to the pirin family
LI64_RS20230	COG0673	inositol 2-dehydrogenase activity
LI64_RS20235	COG1247	-acetyltransferase
LI64_RS20240	COG0405	Gamma-glutamyltransferase
LI64_RS20250	COG0584	glycerophosphoryl diester phosphodiesterase
LI64_RS20280	COG0411	ABC transporter
LI64_RS20295	COG0683	leucine binding
LI64_RS20310	COG0456	acetyltransferase
LI64_RS20315	COG0683	leucine binding
LI64_RS20320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LI64_RS20325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LI64_RS20330	COG2177	Part of the ABC transporter FtsEX involved in
LI64_RS20335	COG2884	Cell division ATP-binding protein ftsE
LI64_RS20340	COG0552	protein localization to endoplasmic reticulum
LI64_RS20345	COG0742	ribosomal rna small subunit methyltransferase
LI64_RS20350	COG3776	membrane
LI64_RS20360	COG3714	YhhN family
LI64_RS20380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LI64_RS20385	COG0425	Belongs to the sulfur carrier protein TusA family
LI64_RS20390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LI64_RS20400	COG0628	permease
LI64_RS20420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LI64_RS20440	COG1216	Glycosyl transferase, family 2
LI64_RS20465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI64_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS20480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI64_RS20490	COG3479	Phenolic acid decarboxylase
LI64_RS20495	COG0583	DNA-binding transcription factor activity
LI64_RS20500	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS20520	COG1414	Transcriptional regulator
LI64_RS20525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LI64_RS20530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI64_RS20545	COG2205	protein histidine kinase activity
LI64_RS20550	COG0745	RESPONSE REGULATOR receiver
LI64_RS20555	COG1276	copper resistance
LI64_RS20560	COG2372	response to copper ion
LI64_RS20565	COG3667	copper resistance
LI64_RS20570	COG2132	Multicopper oxidase
LI64_RS20580	COG0739	heme binding
LI64_RS20610	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI64_RS20695	COG2081	HI0933 family
LI64_RS20700	COG0306	phosphate transporter
LI64_RS20710	COG0589	response to stress
LI64_RS20720	COG0339	signal peptide processing
LI64_RS20725	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LI64_RS20730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LI64_RS20760	COG2197	response regulator
LI64_RS20765	COG1028	Short-chain dehydrogenase reductase Sdr
LI64_RS20770	COG0583	DNA-binding transcription factor activity
LI64_RS20775	COG1295	ribonuclease BN
LI64_RS20780	COG0477	Major facilitator Superfamily
LI64_RS20785	COG2982	Protein involved in outer membrane biogenesis
LI64_RS20790	COG2200	EAL domain
LI64_RS20800	COG0612	Peptidase, M16
LI64_RS20805	COG1301	dicarboxylic acid transport
LI64_RS20810	COG2199	diguanylate cyclase activity
LI64_RS20810	COG2200	EAL domain
LI64_RS20815	COG3118	belongs to the thioredoxin family
LI64_RS20815	COG0457	Tetratricopeptide repeat
LI64_RS20820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LI64_RS20825	COG1215	transferase activity, transferring glycosyl groups
LI64_RS20855	COG2194	sulfuric ester hydrolase activity
LI64_RS20865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LI64_RS20895	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LI64_RS20905	COG1739	Uncharacterized protein family UPF0029
LI64_RS20910	COG0006	proline dipeptidase activity
LI64_RS20915	COG1024	Enoyl-CoA hydratase
LI64_RS20915	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI64_RS20920	COG0183	Belongs to the thiolase family
LI64_RS20925	COG0751	glycine-tRNA ligase activity
LI64_RS20930	COG0752	glycyl-tRNA synthetase alpha subunit
LI64_RS20940	COG3274	enterobacterial common antigen metabolic process
LI64_RS20945	COG1070	Carbohydrate kinase
LI64_RS20950	COG2115	Belongs to the xylose isomerase family
LI64_RS20955	COG4213	ABC transporter substrate-binding protein
LI64_RS20965	COG4214	carbohydrate transport
LI64_RS20970	COG1609	Transcriptional regulator
LI64_RS20970	COG2207	Transcriptional regulator
LI64_RS20975	COG2992	FlgJ-related protein
LI64_RS20980	COG0366	Alpha amylase catalytic
LI64_RS20985	COG3977	Valine--pyruvate aminotransferase
LI64_RS20990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI64_RS21000	COG2211	Major facilitator Superfamily
LI64_RS21010	COG1012	belongs to the aldehyde dehydrogenase family
LI64_RS21015	COG1940	carbohydrate kinase activity
LI64_RS21020	COG3276	selenocysteine insertion sequence binding
LI64_RS21030	COG0625	glutathione transferase activity
LI64_RS21035	COG1566	PFAM secretion protein HlyD family protein
LI64_RS21045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI64_RS21045	COG2213	PTS system mannitol-specific
LI64_RS21055	COG3722	fumarate hydratase activity
LI64_RS21080	COG3121	Chaperone
LI64_RS21095	COG2186	Transcriptional regulator
LI64_RS21105	COG2271	Major facilitator Superfamily
LI64_RS21110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LI64_RS21120	COG0583	DNA-binding transcription factor activity
LI64_RS21125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LI64_RS21135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LI64_RS21140	COG3978	acetolactate synthase activity
LI64_RS21155	COG3085	chromosome segregation
LI64_RS21205	COG4206	TonB-dependent receptor
LI64_RS21210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI64_RS21230	COG0583	DNA-binding transcription factor activity
LI64_RS21235	COG0165	Argininosuccinate lyase
LI64_RS21250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LI64_RS21255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LI64_RS21265	COG0371	Dehydrogenase
LI64_RS21270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LI64_RS21280	COG0460	homoserine dehydrogenase
LI64_RS21280	COG0527	aspartate kinase activity
LI64_RS21285	COG0626	cystathionine gamma-synthase activity
LI64_RS21300	COG0254	rRNA binding
LI64_RS21305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LI64_RS21310	COG1609	Transcriptional regulator
LI64_RS21315	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LI64_RS21330	COG1575	Belongs to the MenA family. Type 1 subfamily
LI64_RS21335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LI64_RS21340	COG3074	FtsZ-dependent cytokinesis
LI64_RS21345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LI64_RS21355	COG1494	fructose-1,6-bisphosphatase
LI64_RS21365	COG3152	Membrane
LI64_RS21375	COG0149	triose-phosphate isomerase activity
LI64_RS21385	COG2134	cdp-diacylglycerol pyrophosphatase
LI64_RS21395	COG0205	6-phosphofructokinase activity
LI64_RS21415	COG0464	growth
LI64_RS21425	COG3678	ATP-independent chaperone mediated protein folding
LI64_RS21430	COG0745	RESPONSE REGULATOR receiver
LI64_RS21435	COG2205	protein histidine kinase activity
LI64_RS21440	COG2258	MOSC domain
LI64_RS21455	COG1917	Cupin 2, conserved barrel domain protein
LI64_RS21455	COG4977	sequence-specific DNA binding
LI64_RS21460	COG4977	sequence-specific DNA binding
LI64_RS21470	COG1070	Carbohydrate kinase
LI64_RS21475	COG4806	L-rhamnose isomerase
LI64_RS21490	COG1129	ABC transporter
LI64_RS21495	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS21505	COG1454	alcohol dehydrogenase
LI64_RS21520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LI64_RS21535	COG3188	usher protein
LI64_RS21540	COG3121	Chaperone
LI64_RS21560	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS21560	COG0243	molybdopterin cofactor binding
LI64_RS21565	COG3383	formate dehydrogenase (NAD+) activity
LI64_RS21565	COG0243	molybdopterin cofactor binding
LI64_RS21570	COG0437	4 iron, 4 sulfur cluster binding
LI64_RS21575	COG2864	formate dehydrogenase
LI64_RS21580	COG3058	Necessary for formate dehydrogenase activity
LI64_RS21590	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LI64_RS21595	COG0456	acetyltransferase
LI64_RS21610	COG1011	Hydrolase
LI64_RS21615	COG1349	DNA-binding transcription factor activity
LI64_RS21620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS21630	COG3684	Belongs to the aldolase LacD family
LI64_RS21640	COG1501	Belongs to the glycosyl hydrolase 31 family
LI64_RS21655	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI64_RS21670	COG3852	Histidine kinase
LI64_RS21685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LI64_RS21690	COG3078	GTPase activator activity
LI64_RS21705	COG0204	Acyl-transferase
LI64_RS21715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LI64_RS21720	COG3084	Protein conserved in bacteria
LI64_RS21725	COG0746	molybdenum cofactor guanylyltransferase activity
LI64_RS21730	COG1763	Mo-molybdopterin cofactor biosynthetic process
LI64_RS21755	COG2186	Transcriptional regulator
LI64_RS21760	COG0477	Major facilitator Superfamily
LI64_RS21765	COG1609	Transcriptional regulator
LI64_RS21770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI64_RS21780	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI64_RS21785	COG1129	ABC transporter
LI64_RS21790	COG1869	D-ribose catabolic process
LI64_RS21795	COG3158	transport of potassium into the cell
LI64_RS21805	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LI64_RS21810	COG2502	aspartate--ammonia ligase
LI64_RS21815	COG1522	sequence-specific DNA binding
LI64_RS21820	COG0716	FMN binding
LI64_RS21825	COG0445	tRNA wobble uridine modification
LI64_RS21830	COG0357	Ribosomal RNA small subunit methyltransferase G
LI64_RS21835	COG3312	ion transport
LI64_RS21840	COG0356	it plays a direct role in the translocation of protons across the membrane
LI64_RS21850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LI64_RS21855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LI64_RS21860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LI64_RS21870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LI64_RS21875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LI64_RS21880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LI64_RS21890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LI64_RS21895	COG0573	inorganic phosphate transmembrane transporter activity
LI64_RS21900	COG0581	inorganic phosphate transmembrane transporter activity
LI64_RS21905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LI64_RS21910	COG0704	Plays a role in the regulation of phosphate uptake
LI64_RS21915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI64_RS21920	COG2252	PERMEase
LI64_RS21925	COG0431	NADPH-dependent FMN reductase
LI64_RS21930	COG2091	lysine biosynthetic process via aminoadipic acid
LI64_RS21945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LI64_RS21950	COG0706	membrane insertase activity
LI64_RS22010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LI64_RS22055	COG0246	Mannitol dehydrogenase
LI64_RS22150	COG2188	Transcriptional regulator
LI64_RS22210	COG2814	Major facilitator Superfamily
LI64_RS22285	COG2271	Major facilitator Superfamily
LI64_RS22315	COG0583	DNA-binding transcription factor activity
LI64_RS22375	COG0187	DNA topoisomerase II activity
LI64_RS22395	COG0246	Mannitol dehydrogenase
LI64_RS22445	COG2985	domain, Protein
LI64_RS22630	COG4948	Mandelate Racemase Muconate Lactonizing
LI64_RS23115	COG0582	viral genome integration into host DNA
LI64_RS23130	COG1501	Belongs to the glycosyl hydrolase 31 family
LI64_RS23245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI64_RS23265	COG3206	protein involved in exopolysaccharide biosynthesis
LI64_RS23265	COG0489	protein tyrosine kinase activity
LI64_RS23450	COG1063	alcohol dehydrogenase
LI64_RS23695	COG0514	ATP-dependent DNA helicase (RecQ)