locus-tag	class	description
CCL06_RS00010	COG0592	DNA-directed DNA polymerase activity
CCL06_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCL06_RS00020	COG0187	DNA topoisomerase II activity
CCL06_RS00025	COG0583	DNA-binding transcription factor activity
CCL06_RS00030	COG3321	synthase
CCL06_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS00030	COG0604	alcohol dehydrogenase
CCL06_RS00035	COG0561	phosphatase activity
CCL06_RS00040	COG2186	Transcriptional regulator
CCL06_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
CCL06_RS00050	COG0800	Aldolase
CCL06_RS00055	COG4948	Mandelate Racemase Muconate Lactonizing
CCL06_RS00060	COG2271	Major facilitator Superfamily
CCL06_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
CCL06_RS00070	COG5645	(Lipo)protein
CCL06_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
CCL06_RS00085	COG2985	domain, Protein
CCL06_RS00090	COG2188	Transcriptional regulator
CCL06_RS00105	COG2149	membrane
CCL06_RS00120	COG2610	gluconate transmembrane transporter activity
CCL06_RS00125	COG0583	DNA-binding transcription factor activity
CCL06_RS00135	COG2814	Major facilitator Superfamily
CCL06_RS00155	COG4680	protein conserved in bacteria
CCL06_RS00160	COG5499	transcription regulator containing HTH domain
CCL06_RS00170	COG0028	Belongs to the TPP enzyme family
CCL06_RS00175	COG0440	acetolactate synthase activity
CCL06_RS00180	COG2197	response regulator
CCL06_RS00210	COG2161	toxin-antitoxin pair type II binding
CCL06_RS00215	COG4115	mRNA cleavage
CCL06_RS00220	COG0697	spore germination
CCL06_RS00225	COG4580	involved in the transport of maltose and maltodextrins
CCL06_RS00230	COG1447	Phosphotransferase system cellobiose-specific component IIA
CCL06_RS00235	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS00240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS00240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS00250	COG1609	Transcriptional regulator
CCL06_RS00260	COG0454	-acetyltransferase
CCL06_RS00270	COG1487	ribonuclease activity
CCL06_RS00275	COG1464	Belongs to the NlpA lipoprotein family
CCL06_RS00280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCL06_RS00285	COG3272	Protein of unknown function (DUF1722)
CCL06_RS00295	COG0789	Transcriptional regulator
CCL06_RS00310	COG0519	Catalyzes the synthesis of GMP from XMP
CCL06_RS00330	COG1501	Belongs to the glycosyl hydrolase 31 family
CCL06_RS00335	COG2982	Protein involved in outer membrane biogenesis
CCL06_RS00340	COG2233	PERMEase
CCL06_RS00345	COG0786	glutamate:sodium symporter activity
CCL06_RS00355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCL06_RS00370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCL06_RS00375	COG2194	sulfuric ester hydrolase activity
CCL06_RS00380	COG2860	membrane
CCL06_RS00415	COG1561	YicC-like family, N-terminal region
CCL06_RS00430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCL06_RS00445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCL06_RS00450	COG2003	Belongs to the UPF0758 family
CCL06_RS00455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCL06_RS00460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCL06_RS00465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCL06_RS00470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCL06_RS00480	COG1519	Transferase
CCL06_RS00495	COG1216	Glycosyl transferase, family 2
CCL06_RS00510	COG0438	transferase activity, transferring glycosyl groups
CCL06_RS00515	COG0859	PFAM glycosyl transferase family 9
CCL06_RS00525	COG0859	PFAM glycosyl transferase family 9
CCL06_RS00540	COG1063	alcohol dehydrogenase
CCL06_RS00545	COG0463	Glycosyl transferase, family 2
CCL06_RS00550	COG2861	carbohydrate metabolic process
CCL06_RS00555	COG4942	peptidase
CCL06_RS00560	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CCL06_RS00565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCL06_RS00570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCL06_RS00575	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CCL06_RS00580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCL06_RS00590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CCL06_RS00595	COG2271	Major facilitator Superfamily
CCL06_RS00600	COG1304	FMN binding
CCL06_RS00605	COG2186	Transcriptional regulator
CCL06_RS00620	COG3722	fumarate hydratase activity
CCL06_RS00640	COG1566	PFAM secretion protein HlyD family protein
CCL06_RS00645	COG0625	glutathione transferase activity
CCL06_RS00655	COG3276	selenocysteine insertion sequence binding
CCL06_RS00660	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS00665	COG0583	DNA-binding transcription factor activity
CCL06_RS00670	COG3713	MltA-interacting MipA family protein
CCL06_RS00690	COG2211	Major facilitator Superfamily
CCL06_RS00700	COG0235	Class ii aldolase
CCL06_RS00705	COG3623	hexulose-6-phosphate isomerase
CCL06_RS00710	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CCL06_RS00715	COG1070	Carbohydrate kinase
CCL06_RS00720	COG2271	Major facilitator Superfamily
CCL06_RS00730	COG2731	YhcH YjgK YiaL family protein
CCL06_RS00740	COG1414	Transcriptional regulator
CCL06_RS00745	COG3977	Valine--pyruvate aminotransferase
CCL06_RS00750	COG0366	Alpha amylase catalytic
CCL06_RS00760	COG2992	FlgJ-related protein
CCL06_RS00765	COG1609	Transcriptional regulator
CCL06_RS00765	COG2207	Transcriptional regulator
CCL06_RS00770	COG4214	carbohydrate transport
CCL06_RS00780	COG4213	ABC transporter substrate-binding protein
CCL06_RS00790	COG2115	Belongs to the xylose isomerase family
CCL06_RS00795	COG1070	Carbohydrate kinase
CCL06_RS00810	COG3274	enterobacterial common antigen metabolic process
CCL06_RS00820	COG0752	glycyl-tRNA synthetase alpha subunit
CCL06_RS00825	COG0751	glycine-tRNA ligase activity
CCL06_RS00835	COG0488	(ABC) transporter
CCL06_RS00840	COG2944	sequence-specific DNA binding
CCL06_RS00850	COG1278	Cold shock
CCL06_RS00855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCL06_RS00865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS00875	COG1609	Transcriptional regulator
CCL06_RS00880	COG2885	chlorophyll binding
CCL06_RS00885	COG0243	molybdopterin cofactor binding
CCL06_RS00890	COG0456	acetyltransferase
CCL06_RS00895	COG2818	Glycosylase
CCL06_RS00900	COG3039	Transposase
CCL06_RS00925	COG3039	Transposase
CCL06_RS00950	COG5571	outer membrane autotransporter
CCL06_RS00955	COG2223	nitrite transmembrane transporter activity
CCL06_RS00960	COG2194	sulfuric ester hydrolase activity
CCL06_RS00975	COG0747	negative chemotaxis
CCL06_RS00985	COG0601	transmembrane transport
CCL06_RS00990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS00995	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS01000	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS01005	COG1072	(Pantothenic acid kinase))
CCL06_RS01040	COG0250	Participates in transcription elongation, termination and antitermination
CCL06_RS01090	COG2199	diguanylate cyclase activity
CCL06_RS01090	COG2203	Gaf domain
CCL06_RS01100	COG2022	thiamine diphosphate biosynthetic process
CCL06_RS01105	COG2104	thiamine diphosphate biosynthetic process
CCL06_RS01110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CCL06_RS01125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CCL06_RS01130	COG2816	NAD+ diphosphatase activity
CCL06_RS01135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CCL06_RS01145	COG3068	Protein conserved in bacteria
CCL06_RS01160	COG0151	Belongs to the GarS family
CCL06_RS01200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCL06_RS01210	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CCL06_RS01230	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCL06_RS01235	COG3657	addiction module killer protein
CCL06_RS01240	COG1187	pseudouridine synthase activity
CCL06_RS01250	COG0527	aspartate kinase activity
CCL06_RS01275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCL06_RS01280	COG3223	Belongs to the PsiE family
CCL06_RS01305	COG4580	involved in the transport of maltose and maltodextrins
CCL06_RS01335	COG3161	chorismate lyase activity
CCL06_RS01350	COG3714	YhhN family
CCL06_RS01360	COG3776	membrane
CCL06_RS01365	COG0742	ribosomal rna small subunit methyltransferase
CCL06_RS01370	COG0552	protein localization to endoplasmic reticulum
CCL06_RS01375	COG2884	Cell division ATP-binding protein ftsE
CCL06_RS01380	COG2177	Part of the ABC transporter FtsEX involved in
CCL06_RS01385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCL06_RS01390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS01395	COG0683	leucine binding
CCL06_RS01410	COG0683	leucine binding
CCL06_RS01420	COG4177	L-phenylalanine transmembrane transporter activity
CCL06_RS01425	COG0411	ABC transporter
CCL06_RS01455	COG0584	glycerophosphoryl diester phosphodiesterase
CCL06_RS01465	COG0405	Gamma-glutamyltransferase
CCL06_RS01470	COG1247	-acetyltransferase
CCL06_RS01475	COG0673	inositol 2-dehydrogenase activity
CCL06_RS01480	COG1741	Belongs to the pirin family
CCL06_RS01485	COG1609	Transcriptional regulator
CCL06_RS01490	COG3265	gluconokinase activity
CCL06_RS01495	COG2610	gluconate transmembrane transporter activity
CCL06_RS01500	COG2937	Belongs to the GPAT DAPAT family
CCL06_RS01505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCL06_RS01510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCL06_RS01515	COG0534	Mate efflux family protein
CCL06_RS01525	COG0735	belongs to the Fur family
CCL06_RS01540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCL06_RS01550	COG0604	alcohol dehydrogenase
CCL06_RS01555	COG0305	Participates in initiation and elongation during chromosome replication
CCL06_RS01565	COG1448	Aminotransferase
CCL06_RS01570	COG3700	Belongs to the class B bacterial acid phosphatase family
CCL06_RS01580	COG2315	Protein conserved in bacteria
CCL06_RS01590	COG0629	single-stranded DNA binding
CCL06_RS01600	COG2199	diguanylate cyclase activity
CCL06_RS01605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CCL06_RS01615	COG0789	Transcriptional regulator
CCL06_RS01625	COG2252	PERMEase
CCL06_RS01635	COG0025	NhaP-type Na H and K H
CCL06_RS01640	COG0583	DNA-binding transcription factor activity
CCL06_RS01645	COG1380	Effector of murein hydrolase LrgA
CCL06_RS01650	COG1346	cytolysis
CCL06_RS01655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCL06_RS01660	COG3162	membrane
CCL06_RS01670	COG1301	dicarboxylic acid transport
CCL06_RS01675	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CCL06_RS01700	COG0191	fructose-bisphosphate aldolase activity
CCL06_RS01715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS01720	COG1129	ABC transporter
CCL06_RS01725	COG4191	Histidine kinase
CCL06_RS01725	COG0784	Response regulator, receiver
CCL06_RS01735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CCL06_RS01740	COG0456	acetyltransferase
CCL06_RS01745	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CCL06_RS01750	COG3454	Phosphonate metabolism
CCL06_RS01755	COG4778	phosphonate C-P lyase system protein PhnL
CCL06_RS01760	COG4107	phosphonate C-P lyase system protein PhnK
CCL06_RS01765	COG3627	carbon phosphorus lyase activity
CCL06_RS01770	COG3626	phosphonate metabolism
CCL06_RS01775	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CCL06_RS01780	COG3624	Phosphonate C-P lyase system protein PhnG
CCL06_RS01785	COG2188	Transcriptional regulator
CCL06_RS01790	COG3639	organic phosphonate transmembrane transporter activity
CCL06_RS01795	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CCL06_RS01800	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CCL06_RS01805	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CCL06_RS01810	COG2824	Alkylphosphonate utilization operon protein PhnA
CCL06_RS01815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CCL06_RS01825	COG2801	Transposase and inactivated derivatives
CCL06_RS01825	COG3415	Transposase
CCL06_RS01840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CCL06_RS01915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCL06_RS01925	COG0629	single-stranded DNA binding
CCL06_RS02085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCL06_RS02090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCL06_RS02165	COG2205	protein histidine kinase activity
CCL06_RS02180	COG1309	transcriptional regulator
CCL06_RS02195	COG1136	(ABC) transporter
CCL06_RS02230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCL06_RS02275	COG1192	Involved in chromosome partitioning
CCL06_RS02290	COG0457	Tetratricopeptide repeat
CCL06_RS02350	COG0840	transmembrane signaling receptor activity
CCL06_RS02355	COG3039	Transposase
CCL06_RS02380	COG1342	Belongs to the UPF0251 family
CCL06_RS02405	COG0783	Belongs to the Dps family
CCL06_RS02410	COG0640	Transcriptional regulator
CCL06_RS02415	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCL06_RS02420	COG3335	DDE superfamily endonuclease
CCL06_RS02425	COG3039	Transposase
CCL06_RS02480	COG0210	DNA helicase
CCL06_RS02490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCL06_RS02500	COG1309	transcriptional regulator
CCL06_RS02515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CCL06_RS02520	COG1027	Aspartate ammonia-lyase
CCL06_RS02530	COG3030	protein affecting phage T7 exclusion by the F plasmid
CCL06_RS02535	COG0531	amino acid
CCL06_RS02545	COG0459	protein refolding
CCL06_RS02565	COG5510	response to toxic substance
CCL06_RS02595	COG0583	DNA-binding transcription factor activity
CCL06_RS02605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CCL06_RS02610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCL06_RS02615	COG1053	succinate dehydrogenase
CCL06_RS02620	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CCL06_RS02625	COG1511	domain protein
CCL06_RS02625	COG3264	Mechanosensitive ion channel
CCL06_RS02640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCL06_RS02660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCL06_RS02665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCL06_RS02665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCL06_RS02670	COG0802	atpase or kinase
CCL06_RS02680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCL06_RS02685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCL06_RS02690	COG1923	regulation of RNA biosynthetic process
CCL06_RS02695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCL06_RS02700	COG0330	HflC and HflK could
CCL06_RS02705	COG0330	HflC and HflK could
CCL06_RS02710	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CCL06_RS02720	COG1959	2 iron, 2 sulfur cluster binding
CCL06_RS02725	COG0557	exoribonuclease II activity
CCL06_RS02730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCL06_RS02735	COG0477	Major facilitator Superfamily
CCL06_RS02740	COG1960	acyl-CoA dehydrogenase activity
CCL06_RS02745	COG0840	transmembrane signaling receptor activity
CCL06_RS02755	COG3650	response to hydrogen peroxide
CCL06_RS02760	COG1073	alpha beta
CCL06_RS02775	COG3037	sugar-specific permease SgaT UlaA
CCL06_RS02815	COG2965	DNA replication, synthesis of RNA primer
CCL06_RS02820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCL06_RS02825	COG0359	binds to the 23S rRNA
CCL06_RS02830	COG3061	Opacity-associated protein A
CCL06_RS02835	COG0545	Peptidyl-prolyl cis-trans isomerase
CCL06_RS02840	COG1113	amino acid transport
CCL06_RS02850	COG0840	transmembrane signaling receptor activity
CCL06_RS02855	COG0697	spore germination
CCL06_RS02865	COG0702	epimerase
CCL06_RS02870	COG1733	regulation of RNA biosynthetic process
CCL06_RS02880	COG1218	3'(2'),5'-bisphosphate nucleotidase
CCL06_RS02885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CCL06_RS02895	COG1253	flavin adenine dinucleotide binding
CCL06_RS02900	COG3157	Type VI secretion system effector, Hcp
CCL06_RS02915	COG0673	inositol 2-dehydrogenase activity
CCL06_RS02925	COG0673	inositol 2-dehydrogenase activity
CCL06_RS02930	COG0673	inositol 2-dehydrogenase activity
CCL06_RS02935	COG1609	Transcriptional regulator
CCL06_RS02945	COG0729	surface antigen
CCL06_RS02950	COG2911	Protein conserved in bacteria
CCL06_RS02955	COG2105	PFAM AIG2 family protein
CCL06_RS02975	COG1879	ABC-type sugar transport system periplasmic component
CCL06_RS02980	COG1129	ABC transporter
CCL06_RS02985	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS02990	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS03000	COG0583	DNA-binding transcription factor activity
CCL06_RS03010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCL06_RS03015	COG3028	Belongs to the UPF0307 family
CCL06_RS03020	COG0312	modulator of DNA gyrase
CCL06_RS03060	COG3964	amidohydrolase
CCL06_RS03075	COG2706	6-phosphogluconolactonase activity
CCL06_RS03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS03080	COG3711	transcriptional antiterminator
CCL06_RS03085	COG3077	Addiction module antitoxin, RelB DinJ family
CCL06_RS03090	COG2026	Addiction module toxin, RelE StbE family
CCL06_RS03095	COG0602	queuosine metabolic process
CCL06_RS03105	COG0366	Alpha amylase catalytic
CCL06_RS03110	COG1263	PTS System
CCL06_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS03115	COG1609	Transcriptional regulator
CCL06_RS03125	COG2801	Transposase and inactivated derivatives
CCL06_RS03125	COG3415	Transposase
CCL06_RS03130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CCL06_RS03135	COG0251	oxidation-reduction process
CCL06_RS03145	COG0540	Belongs to the ATCase OTCase family
CCL06_RS03155	COG1438	arginine binding
CCL06_RS03160	COG1288	antiporter activity
CCL06_RS03175	COG2235	arginine
CCL06_RS03180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCL06_RS03185	COG0129	dihydroxy-acid dehydratase activity
CCL06_RS03190	COG2211	Major facilitator Superfamily
CCL06_RS03195	COG3507	Belongs to the glycosyl hydrolase 43 family
CCL06_RS03200	COG1414	Transcriptional regulator
CCL06_RS03205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCL06_RS03250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCL06_RS03255	COG0514	ATP-dependent DNA helicase (RecQ)
CCL06_RS03295	COG0720	synthase
CCL06_RS03325	COG0789	Transcriptional regulator
CCL06_RS03355	COG1609	Transcriptional regulator
CCL06_RS03365	COG2211	Major facilitator Superfamily
CCL06_RS03370	COG0346	lactoylglutathione lyase activity
CCL06_RS03375	COG1349	DNA-binding transcription factor activity
CCL06_RS03380	COG0740	serine-type endopeptidase activity
CCL06_RS03385	COG2850	peptidyl-arginine hydroxylation
CCL06_RS03390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCL06_RS03395	COG5457	Domain of unknown function (DUF1127)
CCL06_RS03405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCL06_RS03415	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS03425	COG0640	Transcriptional regulator
CCL06_RS03445	COG2733	membrane
CCL06_RS03475	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS03490	COG0523	cobalamin synthesis protein
CCL06_RS03495	COG2879	small protein
CCL06_RS03500	COG1966	Carbon starvation protein
CCL06_RS03510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCL06_RS03515	COG2368	4-hydroxyphenylacetate
CCL06_RS03535	COG3971	2-oxopent-4-enoate hydratase activity
CCL06_RS03545	COG3384	dioxygenase
CCL06_RS03550	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS03555	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCL06_RS03560	COG1846	Transcriptional regulator
CCL06_RS03565	COG0840	transmembrane signaling receptor activity
CCL06_RS03585	COG1484	DNA-dependent DNA replication
CCL06_RS03595	COG1764	response to oxidative stress
CCL06_RS03600	COG1846	Transcriptional regulator
CCL06_RS03605	COG1309	transcriptional regulator
CCL06_RS03610	COG3610	response to peptide
CCL06_RS03615	COG2966	Psort location CytoplasmicMembrane, score
CCL06_RS03620	COG2197	response regulator
CCL06_RS03625	COG2197	response regulator
CCL06_RS03630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCL06_RS03635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS03640	COG4114	ferric iron reductase
CCL06_RS03670	COG2813	Specifically methylates the guanine in position
CCL06_RS03675	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CCL06_RS03680	COG0456	acetyltransferase
CCL06_RS03685	COG1011	Hydrolase
CCL06_RS03695	COG2823	Periplasmic or secreted lipoprotein
CCL06_RS03700	COG5487	UPF0391 membrane protein
CCL06_RS03705	COG4667	esterase of the alpha-beta hydrolase superfamily
CCL06_RS03710	COG0084	hydrolase, TatD family'
CCL06_RS03715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCL06_RS03720	COG1328	CTP reductase activity
CCL06_RS03740	COG0813	purine-nucleoside phosphorylase activity
CCL06_RS03750	COG3726	membrane protein affecting hemolysin expression
CCL06_RS03755	COG0560	Phosphoserine phosphatase
CCL06_RS03760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CCL06_RS03770	COG0604	alcohol dehydrogenase
CCL06_RS03780	COG2801	Transposase and inactivated derivatives
CCL06_RS03780	COG3415	Transposase
CCL06_RS03785	COG0488	(ABC) transporter
CCL06_RS03795	COG0741	lytic transglycosylase activity
CCL06_RS03800	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CCL06_RS03805	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CCL06_RS03810	COG0406	alpha-ribazole phosphatase activity
CCL06_RS03815	COG2207	Transcriptional regulator
CCL06_RS03815	COG3708	Transcriptional regulator
CCL06_RS03820	COG3045	CreA protein
CCL06_RS03825	COG0745	RESPONSE REGULATOR receiver
CCL06_RS03830	COG2205	protein histidine kinase activity
CCL06_RS03835	COG4452	Inner membrane protein CreD
CCL06_RS03840	COG0745	RESPONSE REGULATOR receiver
CCL06_RS03850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CCL06_RS03860	COG0460	homoserine dehydrogenase
CCL06_RS03860	COG0527	aspartate kinase activity
CCL06_RS03870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCL06_RS03885	COG1115	amino acid carrier protein
CCL06_RS03895	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCL06_RS03900	COG0477	Major facilitator Superfamily
CCL06_RS03905	COG1584	GPR1 FUN34 yaaH family protein
CCL06_RS03920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCL06_RS03925	COG0583	DNA-binding transcription factor activity
CCL06_RS03930	COG0268	Binds directly to 16S ribosomal RNA
CCL06_RS03940	COG0196	riboflavin kinase activity
CCL06_RS03955	COG1047	Peptidyl-prolyl cis-trans
CCL06_RS03960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCL06_RS03970	COG0505	Belongs to the CarA family
CCL06_RS03990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCL06_RS03995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCL06_RS03995	COG0475	glutathione-regulated potassium exporter activity
CCL06_RS04010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCL06_RS04015	COG2967	ApaG domain
CCL06_RS04025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCL06_RS04035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CCL06_RS04040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCL06_RS04050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCL06_RS04055	COG0417	DNA replication proofreading
CCL06_RS04060	COG0235	Class ii aldolase
CCL06_RS04065	COG2160	L-arabinose isomerase activity
CCL06_RS04070	COG1069	ribulokinase activity
CCL06_RS04080	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS04090	COG1178	ABC-type Fe3 transport system permease component
CCL06_RS04110	COG2814	Major facilitator Superfamily
CCL06_RS04130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCL06_RS04140	COG0028	Belongs to the TPP enzyme family
CCL06_RS04150	COG1609	Transcriptional regulator
CCL06_RS04155	COG2001	Belongs to the MraZ family
CCL06_RS04170	COG0768	penicillin binding
CCL06_RS04175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCL06_RS04180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCL06_RS04185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCL06_RS04195	COG0772	Belongs to the SEDS family
CCL06_RS04220	COG0849	cell division
CCL06_RS04225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCL06_RS04230	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CCL06_RS04240	COG0653	protein targeting
CCL06_RS04245	COG0494	nUDIX hydrolase
CCL06_RS04250	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CCL06_RS04255	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CCL06_RS04265	COG0516	GMP reductase activity
CCL06_RS04270	COG1459	type II secretion system
CCL06_RS04275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCL06_RS04280	COG4969	Belongs to the N-Me-Phe pilin family
CCL06_RS04290	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCL06_RS04295	COG3725	Membrane protein required for beta-lactamase induction
CCL06_RS04300	COG3940	Belongs to the glycosyl hydrolase 43 family
CCL06_RS04305	COG2211	Major facilitator Superfamily
CCL06_RS04310	COG1113	amino acid transport
CCL06_RS04320	COG2186	Transcriptional regulator
CCL06_RS04325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCL06_RS04330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCL06_RS04335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCL06_RS04350	COG3064	Membrane
CCL06_RS04355	COG1049	propionate catabolic process, 2-methylcitrate cycle
CCL06_RS04370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCL06_RS04380	COG2132	Multicopper oxidase
CCL06_RS04385	COG4993	Dehydrogenase
CCL06_RS04395	COG0288	reversible hydration of carbon dioxide
CCL06_RS04400	COG1131	(ABC) transporter
CCL06_RS04405	COG0842	Transport permease protein
CCL06_RS04410	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS04420	COG3539	Fimbrial protein
CCL06_RS04430	COG3188	usher protein
CCL06_RS04440	COG0726	polysaccharide deacetylase
CCL06_RS04445	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCL06_RS04450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCL06_RS04455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCL06_RS04460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCL06_RS04465	COG0617	tRNA 3'-terminal CCA addition
CCL06_RS04480	COG1489	DNA binding
CCL06_RS04485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CCL06_RS04490	COG1643	Atp-dependent helicase
CCL06_RS04495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCL06_RS04505	COG4774	siderophore transport
CCL06_RS04510	COG1120	ATPase activity
CCL06_RS04515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCL06_RS04520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS04525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCL06_RS04540	COG2860	membrane
CCL06_RS04550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCL06_RS04555	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCL06_RS04565	COG3835	regulator
CCL06_RS04595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCL06_RS04610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCL06_RS04620	COG0575	Belongs to the CDS family
CCL06_RS04625	COG0750	zinc metalloprotease
CCL06_RS04630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCL06_RS04640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCL06_RS04645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCL06_RS04650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCL06_RS04655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCL06_RS04660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCL06_RS04675	COG1982	Orn Lys Arg decarboxylase major
CCL06_RS04680	COG0346	lactoylglutathione lyase activity
CCL06_RS04685	COG0037	tRNA processing
CCL06_RS04690	COG4568	rho-dependent transcription termination
CCL06_RS04705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CCL06_RS04710	COG3015	lipoprotein NlpE involved in copper resistance
CCL06_RS04720	COG1720	tRNA m6t6A37 methyltransferase activity
CCL06_RS04730	COG1464	Belongs to the NlpA lipoprotein family
CCL06_RS04735	COG2011	ABC-type metal ion transport system permease component
CCL06_RS04745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCL06_RS04790	COG0583	DNA-binding transcription factor activity
CCL06_RS04795	COG2814	Major facilitator Superfamily
CCL06_RS04800	COG3021	interspecies interaction between organisms
CCL06_RS04805	COG2226	methyltransferase
CCL06_RS04810	COG1388	LysM domain
CCL06_RS04810	COG0741	lytic transglycosylase activity
CCL06_RS04815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCL06_RS04820	COG2226	methyltransferase
CCL06_RS04830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCL06_RS04855	COG1596	polysaccharide export
CCL06_RS04860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCL06_RS04870	COG3210	domain, Protein
CCL06_RS04880	COG0736	holo-[acyl-carrier-protein] synthase activity
CCL06_RS04890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCL06_RS04895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCL06_RS04905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCL06_RS04930	COG2177	Part of the ABC transporter FtsEX involved in
CCL06_RS04985	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS04990	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS05005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS05015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCL06_RS05020	COG1960	acyl-CoA dehydrogenase activity
CCL06_RS05030	COG0121	glutamine amidotransferase
CCL06_RS05035	COG3034	peptidoglycan biosynthetic process
CCL06_RS05050	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CCL06_RS05055	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CCL06_RS05070	COG2991	Protein conserved in bacteria
CCL06_RS05075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCL06_RS05080	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCL06_RS05090	COG1073	alpha beta
CCL06_RS05100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCL06_RS05105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCL06_RS05110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCL06_RS05120	COG0582	viral genome integration into host DNA
CCL06_RS05130	COG1074	ATP-dependent DNA helicase activity
CCL06_RS05135	COG1196	nuclear chromosome segregation
CCL06_RS05155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCL06_RS05210	COG5001	Diguanylate cyclase
CCL06_RS05210	COG3300	MHYT domain
CCL06_RS05240	COG0583	DNA-binding transcription factor activity
CCL06_RS05250	COG0628	permease
CCL06_RS05255	COG0833	amino acid
CCL06_RS05260	COG2040	homocysteine
CCL06_RS05265	COG4521	taurine ABC transporter
CCL06_RS05270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CCL06_RS05275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCL06_RS05280	COG2175	clavaminate synthase activity
CCL06_RS05290	COG0113	porphobilinogen synthase activity
CCL06_RS05305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CCL06_RS05315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CCL06_RS05335	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCL06_RS05355	COG1785	Belongs to the alkaline phosphatase family
CCL06_RS05365	COG3706	GGDEF domain
CCL06_RS05370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCL06_RS05375	COG1671	Belongs to the UPF0178 family
CCL06_RS05380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCL06_RS05390	COG4126	flavin adenine dinucleotide binding
CCL06_RS05395	COG3123	guanosine phosphorylase activity
CCL06_RS05405	COG1940	carbohydrate kinase activity
CCL06_RS05410	COG0419	ATPase involved in DNA repair
CCL06_RS05415	COG0420	3'-5' exonuclease activity
CCL06_RS05425	COG5002	protein histidine kinase activity
CCL06_RS05440	COG0366	Alpha amylase catalytic
CCL06_RS05455	COG0450	alkyl hydroperoxide reductase
CCL06_RS05460	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CCL06_RS05475	COG1862	Preprotein translocase
CCL06_RS05480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCL06_RS05485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCL06_RS05500	COG3248	Nucleoside-binding outer membrane protein
CCL06_RS05505	COG4238	major outer membrane lipoprotein
CCL06_RS05510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCL06_RS05515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCL06_RS05515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCL06_RS05520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCL06_RS05525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCL06_RS05530	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CCL06_RS05535	COG0667	Aldo Keto reductase
CCL06_RS05540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCL06_RS05545	COG0142	geranyltranstransferase activity
CCL06_RS05560	COG0693	protein deglycase activity
CCL06_RS05575	COG2814	Major facilitator Superfamily
CCL06_RS05580	COG0109	protoheme IX farnesyltransferase activity
CCL06_RS05585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCL06_RS05590	COG1845	cytochrome c oxidase, subunit III
CCL06_RS05595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCL06_RS05600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCL06_RS05605	COG2223	nitrite transmembrane transporter activity
CCL06_RS05610	COG3056	Lipoprotein
CCL06_RS05615	COG0271	Belongs to the BolA IbaG family
CCL06_RS05625	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCL06_RS05640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCL06_RS05645	COG0776	regulation of translation
CCL06_RS05650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCL06_RS05655	COG1555	photosystem II stabilization
CCL06_RS05660	COG0824	Thioesterase
CCL06_RS05665	COG3657	addiction module killer protein
CCL06_RS05675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCL06_RS05680	COG4533	DNA binding
CCL06_RS05685	COG0561	phosphatase activity
CCL06_RS05695	COG1522	sequence-specific DNA binding
CCL06_RS05700	COG1132	(ABC) transporter
CCL06_RS05705	COG1132	(ABC) transporter
CCL06_RS05710	COG0347	Belongs to the P(II) protein family
CCL06_RS05715	COG0004	ammonium transporteR
CCL06_RS05720	COG1946	Acyl-CoA thioesterase
CCL06_RS05725	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CCL06_RS05730	COG3695	enzyme binding
CCL06_RS05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCL06_RS05765	COG2364	Membrane
CCL06_RS05770	COG1609	Transcriptional regulator
CCL06_RS05790	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CCL06_RS05800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCL06_RS05820	COG0110	maltose O-acetyltransferase activity
CCL06_RS05835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS05840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS05845	COG1309	transcriptional regulator
CCL06_RS05850	COG1196	nuclear chromosome segregation
CCL06_RS05850	COG3264	Mechanosensitive ion channel
CCL06_RS05860	COG3923	Primosomal replication protein n
CCL06_RS05865	COG2832	Protein of unknown function (DUF454)
CCL06_RS05870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCL06_RS05880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCL06_RS05885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCL06_RS05890	COG0326	Molecular chaperone. Has ATPase activity
CCL06_RS05900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCL06_RS05905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS05910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCL06_RS05910	COG4651	solute:proton antiporter activity
CCL06_RS05915	COG2223	nitrite transmembrane transporter activity
CCL06_RS05920	COG0737	Belongs to the 5'-nucleotidase family
CCL06_RS05925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCL06_RS05935	COG3735	TraB family
CCL06_RS05950	COG1585	Membrane protein implicated in regulation of membrane protease activity
CCL06_RS05955	COG0330	HflC and HflK could
CCL06_RS05960	COG4619	ABC transporter
CCL06_RS05965	COG0390	transport system, permease component
CCL06_RS05970	COG3118	belongs to the thioredoxin family
CCL06_RS05975	COG0300	oxidoreductase activity
CCL06_RS05980	COG2755	lipolytic protein G-D-S-L family
CCL06_RS05985	COG4181	ATPase activity
CCL06_RS05990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCL06_RS06005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCL06_RS06010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCL06_RS06020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCL06_RS06025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCL06_RS06035	COG1988	membrane-bound metal-dependent
CCL06_RS06040	COG1609	Transcriptional regulator
CCL06_RS06045	COG2190	(PTS) system
CCL06_RS06045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS06045	COG1263	PTS System
CCL06_RS06050	COG2501	S4 domain
CCL06_RS06100	COG2200	EAL domain
CCL06_RS06110	COG0582	viral genome integration into host DNA
CCL06_RS06240	COG0305	Participates in initiation and elongation during chromosome replication
CCL06_RS06440	COG1196	nuclear chromosome segregation
CCL06_RS06450	COG1674	ftsk spoiiie
CCL06_RS06450	COG1178	ABC-type Fe3 transport system permease component
CCL06_RS06515	COG0583	DNA-binding transcription factor activity
CCL06_RS06520	COG0667	Aldo Keto reductase
CCL06_RS06555	COG1113	amino acid transport
CCL06_RS06560	COG1396	sequence-specific DNA binding
CCL06_RS06570	COG2211	Major facilitator Superfamily
CCL06_RS06585	COG1609	Transcriptional regulator
CCL06_RS06590	COG0668	transmembrane transport
CCL06_RS06595	COG0477	Major facilitator Superfamily
CCL06_RS06620	COG2315	Protein conserved in bacteria
CCL06_RS06635	COG2207	Transcriptional regulator
CCL06_RS06645	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CCL06_RS06660	COG3209	COG3209 Rhs family protein
CCL06_RS06670	COG3209	COG3209 Rhs family protein
CCL06_RS06730	COG3209	COG3209 Rhs family protein
CCL06_RS06785	COG1126	abc transporter atp-binding protein
CCL06_RS06790	COG0765	amino acid transport
CCL06_RS06795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS06805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCL06_RS06840	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS06845	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS06850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS06855	COG0601	transmembrane transport
CCL06_RS06860	COG0747	negative chemotaxis
CCL06_RS06890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCL06_RS06895	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CCL06_RS06910	COG2977	Belongs to the P-Pant transferase superfamily
CCL06_RS06915	COG4771	TonB-dependent receptor
CCL06_RS06920	COG2382	esterase
CCL06_RS06925	COG3251	PFAM MbtH domain protein
CCL06_RS06930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CCL06_RS06930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCL06_RS06935	COG1120	ATPase activity
CCL06_RS06940	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS06945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS06955	COG4592	Periplasmic binding protein
CCL06_RS06960	COG1169	isochorismate synthase
CCL06_RS06965	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCL06_RS06970	COG3433	isochorismatase activity
CCL06_RS06970	COG1535	isochorismatase
CCL06_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS06980	COG2050	protein possibly involved in aromatic compounds catabolism
CCL06_RS06995	COG0700	Nucleoside recognition
CCL06_RS07000	COG3366	ferrous iron transmembrane transporter activity
CCL06_RS07005	COG1966	Carbon starvation protein
CCL06_RS07010	COG2879	small protein
CCL06_RS07030	COG0371	Dehydrogenase
CCL06_RS07035	COG1129	ABC transporter
CCL06_RS07040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS07055	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CCL06_RS07060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CCL06_RS07075	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CCL06_RS07080	COG0235	Class ii aldolase
CCL06_RS07085	COG0436	Aminotransferase
CCL06_RS07090	COG1475	DNA binding
CCL06_RS07095	COG3969	phosphoadenosine phosphosulfate
CCL06_RS07100	COG0583	DNA-binding transcription factor activity
CCL06_RS07120	COG1063	alcohol dehydrogenase
CCL06_RS07125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCL06_RS07130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCL06_RS07135	COG3719	Belongs to the RNase T2 family
CCL06_RS07140	COG3069	C4-dicarboxylate transmembrane transporter activity
CCL06_RS07155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCL06_RS07160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCL06_RS07165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCL06_RS07170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCL06_RS07175	COG0583	DNA-binding transcription factor activity
CCL06_RS07180	COG0321	lipoyl(octanoyl) transferase activity
CCL06_RS07190	COG1686	Belongs to the peptidase S11 family
CCL06_RS07195	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCL06_RS07200	COG0772	Belongs to the SEDS family
CCL06_RS07205	COG0768	penicillin binding
CCL06_RS07215	COG0799	negative regulation of ribosome biogenesis
CCL06_RS07230	COG1466	dna polymerase III delta subunit
CCL06_RS07245	COG2888	peptidyl-tyrosine sulfation
CCL06_RS07250	COG1957	nucleoside hydrolase
CCL06_RS07255	COG1126	abc transporter atp-binding protein
CCL06_RS07260	COG0765	amino acid transport
CCL06_RS07265	COG0765	amino acid transport
CCL06_RS07280	COG4535	Mg2 and Co2 transporter CorC
CCL06_RS07285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCL06_RS07290	COG1702	phosphate starvation-inducible protein PhoH
CCL06_RS07295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCL06_RS07300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCL06_RS07340	COG0367	asparagine synthase
CCL06_RS07345	COG0647	UMP catabolic process
CCL06_RS07350	COG1940	carbohydrate kinase activity
CCL06_RS07350	COG1846	Transcriptional regulator
CCL06_RS07355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCL06_RS07365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS07365	COG1263	PTS System
CCL06_RS07365	COG2190	(PTS) system
CCL06_RS07370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCL06_RS07385	COG0735	belongs to the Fur family
CCL06_RS07400	COG0596	Alpha beta hydrolase
CCL06_RS07405	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CCL06_RS07410	COG0033	Phosphoglucomutase
CCL06_RS07415	COG0531	amino acid
CCL06_RS07420	COG1982	Orn Lys Arg decarboxylase major
CCL06_RS07430	COG0745	RESPONSE REGULATOR receiver
CCL06_RS07435	COG2205	protein histidine kinase activity
CCL06_RS07440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CCL06_RS07445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CCL06_RS07450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CCL06_RS07470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCL06_RS07475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCL06_RS07480	COG1984	allophanate hydrolase subunit 2
CCL06_RS07490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCL06_RS07495	COG0372	Belongs to the citrate synthase family
CCL06_RS07505	COG2009	succinate dehydrogenase
CCL06_RS07510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CCL06_RS07515	COG1053	succinate dehydrogenase
CCL06_RS07520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCL06_RS07525	COG0567	Dehydrogenase, E1 component
CCL06_RS07530	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCL06_RS07535	COG0045	succinate-CoA ligase (ADP-forming) activity
CCL06_RS07540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CCL06_RS07545	COG1271	oxidase subunit
CCL06_RS07550	COG1294	oxidase, subunit
CCL06_RS07555	COG4890	Cyd operon protein YbgT
CCL06_RS07560	COG3790	cyd operon protein YbgE
CCL06_RS07565	COG0824	Thioesterase
CCL06_RS07570	COG0811	peptide transport
CCL06_RS07575	COG0848	biopolymer transport protein
CCL06_RS07580	COG3064	Membrane
CCL06_RS07590	COG2885	chlorophyll binding
CCL06_RS07595	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CCL06_RS07625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCL06_RS07630	COG3201	nicotinamide mononucleotide transporter
CCL06_RS07635	COG1230	cation diffusion facilitator family transporter
CCL06_RS07645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCL06_RS07655	COG2017	converts alpha-aldose to the beta-anomer
CCL06_RS07660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CCL06_RS07665	COG1085	galactose-1-phosphate uridylyltransferase
CCL06_RS07670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCL06_RS07675	COG1119	ATPase activity
CCL06_RS07680	COG3585	molybdate ion transport
CCL06_RS07680	COG2005	Transcriptional regulator
CCL06_RS07690	COG0725	ABC transporter, periplasmic molybdate-binding protein
CCL06_RS07695	COG4149	molybdate abc transporter
CCL06_RS07705	COG0561	phosphatase activity
CCL06_RS07710	COG2706	6-phosphogluconolactonase activity
CCL06_RS07720	COG4677	pectinesterase activity
CCL06_RS07730	COG0010	Belongs to the arginase family
CCL06_RS07740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CCL06_RS07745	COG2986	histidine ammonia-lyase
CCL06_RS07750	COG1881	PFAM PEBP family protein
CCL06_RS07755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCL06_RS07760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCL06_RS07765	COG0156	8-amino-7-oxononanoate synthase activity
CCL06_RS07770	COG2226	methyltransferase
CCL06_RS07780	COG0410	ABC transporter
CCL06_RS07805	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCL06_RS07810	COG0315	cyclic pyranopterin monophosphate synthase activity
CCL06_RS07815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CCL06_RS07820	COG0314	molybdopterin synthase activity
CCL06_RS07825	COG0670	Belongs to the BI1 family
CCL06_RS07830	COG0392	lysyltransferase activity
CCL06_RS07835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCL06_RS07840	COG3568	Endonuclease Exonuclease Phosphatase
CCL06_RS07850	COG0842	Transport permease protein
CCL06_RS07855	COG0842	Transport permease protein
CCL06_RS07860	COG1131	(ABC) transporter
CCL06_RS07865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS07870	COG1309	transcriptional regulator
CCL06_RS07875	COG0513	Belongs to the DEAD box helicase family
CCL06_RS07900	COG3121	Chaperone
CCL06_RS07910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCL06_RS07920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCL06_RS07930	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CCL06_RS07935	COG0668	transmembrane transport
CCL06_RS07940	COG1126	abc transporter atp-binding protein
CCL06_RS07945	COG0765	amino acid transport
CCL06_RS07950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS07960	COG0783	Belongs to the Dps family
CCL06_RS07970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CCL06_RS07975	COG2194	sulfuric ester hydrolase activity
CCL06_RS07985	COG1321	iron dependent repressor
CCL06_RS07990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCL06_RS07995	COG1566	PFAM secretion protein HlyD family protein
CCL06_RS08000	COG2814	Major facilitator Superfamily
CCL06_RS08010	COG0667	Aldo Keto reductase
CCL06_RS08015	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS08020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS08025	COG2188	Transcriptional regulator
CCL06_RS08030	COG1376	ErfK ybiS ycfS ynhG family protein
CCL06_RS08035	COG0488	(ABC) transporter
CCL06_RS08045	COG2271	Major facilitator Superfamily
CCL06_RS08050	COG1609	Transcriptional regulator
CCL06_RS08060	COG0561	phosphatase activity
CCL06_RS08065	COG1882	Formate acetyltransferase
CCL06_RS08070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCL06_RS08075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCL06_RS08085	COG3415	Transposase
CCL06_RS08085	COG2801	Transposase and inactivated derivatives
CCL06_RS08095	COG0303	'Molybdopterin
CCL06_RS08100	COG1446	asparaginase
CCL06_RS08135	COG2133	pyrroloquinoline quinone binding
CCL06_RS08140	COG0625	glutathione transferase activity
CCL06_RS08145	COG1686	Belongs to the peptidase S11 family
CCL06_RS08150	COG1349	DNA-binding transcription factor activity
CCL06_RS08155	COG0671	phosphoesterase, PA-phosphatase related
CCL06_RS08165	COG2814	Major facilitator Superfamily
CCL06_RS08170	COG0561	phosphatase activity
CCL06_RS08175	COG0738	Major facilitator superfamily
CCL06_RS08180	COG3226	Transcriptional regulator
CCL06_RS08185	COG1393	Belongs to the ArsC family
CCL06_RS08190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCL06_RS08195	COG0640	Transcriptional regulator
CCL06_RS08205	COG0569	domain protein
CCL06_RS08205	COG2985	domain, Protein
CCL06_RS08220	COG0778	Nitroreductase
CCL06_RS08225	COG0189	ligase activity
CCL06_RS08235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCL06_RS08240	COG3842	ATPase activity
CCL06_RS08245	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCL06_RS08250	COG1177	transmembrane transport
CCL06_RS08260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCL06_RS08265	COG0745	RESPONSE REGULATOR receiver
CCL06_RS08270	COG5002	protein histidine kinase activity
CCL06_RS08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS08280	COG4160	amino acid transport
CCL06_RS08285	COG4215	(ABC) transporter
CCL06_RS08290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS08295	COG1126	abc transporter atp-binding protein
CCL06_RS08310	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCL06_RS08335	COG1450	Type ii and iii secretion system protein
CCL06_RS08340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCL06_RS08345	COG1459	type II secretion system
CCL06_RS08350	COG2165	general secretion pathway protein
CCL06_RS08360	COG2165	general secretion pathway protein
CCL06_RS08385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCL06_RS08400	COG3397	chitin binding
CCL06_RS08405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCL06_RS08410	COG0702	epimerase
CCL06_RS08415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CCL06_RS08420	COG0028	Belongs to the TPP enzyme family
CCL06_RS08430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCL06_RS08435	COG1151	hydroxylamine reductase activity
CCL06_RS08440	COG2431	L-lysine efflux transmembrane transporter activity
CCL06_RS08450	COG3593	DNA synthesis involved in DNA repair
CCL06_RS08455	COG2990	Protein conserved in bacteria
CCL06_RS08460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS08470	COG1278	Cold shock
CCL06_RS08475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCL06_RS08480	COG0542	response to heat
CCL06_RS08485	COG5654	RES domain protein
CCL06_RS08490	COG5642	Protein of unknown function (DUF2384)
CCL06_RS08505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCL06_RS08510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CCL06_RS08515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CCL06_RS08520	COG4988	ABC transporter
CCL06_RS08525	COG0492	ferredoxin-NADP+ reductase activity
CCL06_RS08540	COG1674	ftsk spoiiie
CCL06_RS08540	COG1178	ABC-type Fe3 transport system permease component
CCL06_RS08545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CCL06_RS08550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCL06_RS08555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCL06_RS08560	COG0243	molybdopterin cofactor binding
CCL06_RS08565	COG0437	4 iron, 4 sulfur cluster binding
CCL06_RS08570	COG3302	dmso reductase anchor subunit
CCL06_RS08575	COG0477	Major facilitator Superfamily
CCL06_RS08585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCL06_RS08590	COG1882	Formate acetyltransferase
CCL06_RS08595	COG2116	formate transmembrane transporter activity
CCL06_RS08600	COG1944	ATP diphosphatase activity
CCL06_RS08605	COG2323	membrane
CCL06_RS08610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCL06_RS08615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCL06_RS08620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCL06_RS08625	COG0539	negative regulation of cytoplasmic translation
CCL06_RS08630	COG0776	regulation of translation
CCL06_RS08635	COG0658	competence protein
CCL06_RS08635	COG2333	competence protein COMEC
CCL06_RS08650	COG3214	Protein conserved in bacteria
CCL06_RS08655	COG2835	tetraacyldisaccharide 4'-kinase activity
CCL06_RS08660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CCL06_RS08665	COG3173	Aminoglycoside phosphotransferase
CCL06_RS08670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCL06_RS08690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CCL06_RS08695	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CCL06_RS08700	COG1388	LysM domain
CCL06_RS08700	COG1470	cell adhesion involved in biofilm formation
CCL06_RS08705	COG2989	Protein conserved in bacteria
CCL06_RS08710	COG3108	Peptidase M15
CCL06_RS08715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCL06_RS08720	COG1448	Aminotransferase
CCL06_RS08735	COG0017	Asparaginyl-tRNA synthetase
CCL06_RS08740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCL06_RS08745	COG0308	aminopeptidase N
CCL06_RS08755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCL06_RS08760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS08765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCL06_RS08770	COG0431	NADPH-dependent FMN reductase
CCL06_RS08780	COG0167	dihydroorotate dehydrogenase activity
CCL06_RS08790	COG3217	Mosc domain protein beta barrel domain protein
CCL06_RS08790	COG0633	Ferredoxin
CCL06_RS08795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCL06_RS08795	COG0116	Belongs to the methyltransferase superfamily
CCL06_RS08800	COG0488	(ABC) transporter
CCL06_RS08805	COG2995	paraquat-inducible protein a
CCL06_RS08810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCL06_RS08810	COG3008	intermembrane lipid transfer
CCL06_RS08815	COG3009	Protein conserved in bacteria
CCL06_RS08820	COG3130	regulation of translation
CCL06_RS08830	COG1067	ATP-dependent peptidase activity
CCL06_RS08835	COG3120	sequence-specific DNA binding
CCL06_RS08845	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CCL06_RS08850	COG3070	regulator of competence-specific genes
CCL06_RS08855	COG1289	transmembrane transporter activity
CCL06_RS08860	COG3304	Inner membrane component domain
CCL06_RS08865	COG0210	DNA helicase
CCL06_RS08870	COG1803	Methylglyoxal synthase
CCL06_RS08875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CCL06_RS08885	COG1832	CoA-binding protein
CCL06_RS08895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCL06_RS08905	COG1881	PFAM PEBP family protein
CCL06_RS08915	COG1254	Belongs to the acylphosphatase family
CCL06_RS08920	COG2920	part of a sulfur-relay system
CCL06_RS08925	COG0670	Belongs to the BI1 family
CCL06_RS08960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCL06_RS08965	COG1696	Membrane protein involved in D-alanine export
CCL06_RS08980	COG0583	DNA-binding transcription factor activity
CCL06_RS08990	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS08990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS09000	COG1301	dicarboxylic acid transport
CCL06_RS09015	COG3799	methylaspartate ammonia-lyase activity
CCL06_RS09020	COG4865	methylaspartate mutase activity
CCL06_RS09030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCL06_RS09035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCL06_RS09035	COG1648	precorrin-2 dehydrogenase activity
CCL06_RS09045	COG1648	precorrin-2 dehydrogenase activity
CCL06_RS09045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCL06_RS09140	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CCL06_RS09150	COG0406	alpha-ribazole phosphatase activity
CCL06_RS09155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCL06_RS09170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCL06_RS09175	COG3195	allantoin biosynthetic process
CCL06_RS09175	COG3648	Uricase
CCL06_RS09180	COG2351	hydroxyisourate hydrolase activity
CCL06_RS09185	COG0402	S-adenosylhomocysteine deaminase activity
CCL06_RS09190	COG1953	Uracil, thiamine, allantoin
CCL06_RS09245	COG0765	amino acid transport
CCL06_RS09250	COG1126	abc transporter atp-binding protein
CCL06_RS09255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CCL06_RS09270	COG2182	Extracellular solute-binding protein
CCL06_RS09275	COG1175	transmembrane transport
CCL06_RS09280	COG3833	ABC-type maltose transport systems, permease component
CCL06_RS09285	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CCL06_RS09290	COG1874	Beta-galactosidase
CCL06_RS09295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS09295	COG1263	PTS System
CCL06_RS09310	COG2239	Acts as a magnesium transporter
CCL06_RS09320	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS09330	COG1733	regulation of RNA biosynthetic process
CCL06_RS09335	COG4221	oxidoreductase activity
CCL06_RS09355	COG0655	NAD(P)H dehydrogenase (quinone) activity
CCL06_RS09360	COG3729	General stress protein
CCL06_RS09380	COG2233	PERMEase
CCL06_RS09385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCL06_RS09390	COG0778	Nitroreductase
CCL06_RS09395	COG2267	carboxylic ester hydrolase activity
CCL06_RS09400	COG0251	oxidation-reduction process
CCL06_RS09405	COG1335	isochorismatase
CCL06_RS09410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS09425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCL06_RS09435	COG1309	transcriptional regulator
CCL06_RS09445	COG0506	proline dehydrogenase activity
CCL06_RS09445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCL06_RS09445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCL06_RS09450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCL06_RS09460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCL06_RS09475	COG2822	iron ion transport
CCL06_RS09485	COG1702	phosphate starvation-inducible protein PhoH
CCL06_RS09495	COG1335	isochorismatase
CCL06_RS09505	COG0583	DNA-binding transcription factor activity
CCL06_RS09520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCL06_RS09525	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CCL06_RS09530	COG3381	protein complex oligomerization
CCL06_RS09555	COG2197	response regulator
CCL06_RS09580	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CCL06_RS09600	COG2943	transferase activity, transferring hexosyl groups
CCL06_RS09605	COG5645	(Lipo)protein
CCL06_RS09620	COG1560	Kdo2-lipid A biosynthetic process
CCL06_RS09625	COG1054	Belongs to the UPF0176 family
CCL06_RS09630	COG2353	YceI-like domain
CCL06_RS09635	COG3038	cytochrome b561
CCL06_RS09660	COG0418	dihydroorotase activity
CCL06_RS09670	COG0477	Major facilitator Superfamily
CCL06_RS09675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCL06_RS09680	COG3132	Protein of unknown function, DUF480
CCL06_RS09690	COG0728	peptidoglycan biosynthetic process
CCL06_RS09715	COG1558	bacterial-type flagellum-dependent cell motility
CCL06_RS09720	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CCL06_RS09725	COG1749	Flagellar hook protein flgE
CCL06_RS09735	COG4786	Flagellar basal body rod
CCL06_RS09755	COG1256	bacterial-type flagellum assembly
CCL06_RS09765	COG2814	Major facilitator Superfamily
CCL06_RS09770	COG0583	DNA-binding transcription factor activity
CCL06_RS09775	COG1530	ribonuclease E activity
CCL06_RS09785	COG0564	pseudouridine synthase activity
CCL06_RS09800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCL06_RS09805	COG0416	fatty acid biosynthetic process
CCL06_RS09810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCL06_RS09825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCL06_RS09830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCL06_RS09835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS09840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCL06_RS09845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCL06_RS09850	COG0470	DNA polymerase III
CCL06_RS09855	COG0084	hydrolase, TatD family'
CCL06_RS09865	COG0537	adenosine 5'-monophosphoramidase activity
CCL06_RS09870	COG5633	Lipoprotein
CCL06_RS09875	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CCL06_RS09890	COG3150	esterase
CCL06_RS09895	COG1252	NADH dehydrogenase
CCL06_RS09900	COG3134	Outer membrane lipoprotein
CCL06_RS09905	COG1309	transcriptional regulator
CCL06_RS09950	COG1376	ErfK ybiS ycfS ynhG family protein
CCL06_RS09950	COG1388	LysM domain
CCL06_RS09955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCL06_RS09960	COG4763	Acyl-transferase
CCL06_RS09965	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCL06_RS09970	COG1136	(ABC) transporter
CCL06_RS09975	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCL06_RS09985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCL06_RS09990	COG0840	transmembrane signaling receptor activity
CCL06_RS09995	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CCL06_RS10025	COG1943	Transposase
CCL06_RS10030	COG2850	peptidyl-arginine hydroxylation
CCL06_RS10035	COG2205	protein histidine kinase activity
CCL06_RS10045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCL06_RS10050	COG2915	High frequency lysogenization protein hflD homolog
CCL06_RS10065	COG1187	pseudouridine synthase activity
CCL06_RS10070	COG0538	isocitrate dehydrogenase activity
CCL06_RS10085	COG5001	Diguanylate cyclase
CCL06_RS10085	COG3300	MHYT domain
CCL06_RS10090	COG2200	EAL domain
CCL06_RS10095	COG5001	Diguanylate cyclase
CCL06_RS10095	COG4251	negative regulation of phosphorylation
CCL06_RS10095	COG2203	Gaf domain
CCL06_RS10095	COG3706	GGDEF domain
CCL06_RS10105	COG2261	transglycosylase associated protein
CCL06_RS10115	COG2199	diguanylate cyclase activity
CCL06_RS10115	COG2203	Gaf domain
CCL06_RS10120	COG3042	response to heat
CCL06_RS10130	COG3189	MarR family transcriptional regulator
CCL06_RS10135	COG0504	CTP synthase activity
CCL06_RS10140	COG2807	transmembrane transport
CCL06_RS10145	COG2207	Transcriptional regulator
CCL06_RS10150	COG2707	UPF0756 membrane protein
CCL06_RS10160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCL06_RS10165	COG0582	viral genome integration into host DNA
CCL06_RS10255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CCL06_RS10265	COG1403	HNH endonuclease
CCL06_RS10290	COG3179	chitinase
CCL06_RS10345	COG0740	serine-type endopeptidase activity
CCL06_RS10385	COG1196	nuclear chromosome segregation
CCL06_RS10440	COG2718	Belongs to the UPF0229 family
CCL06_RS10445	COG2766	serine protein kinase
CCL06_RS10450	COG3713	MltA-interacting MipA family protein
CCL06_RS10470	COG3139	Protein of unknown function (DUF1315)
CCL06_RS10480	COG1335	isochorismatase
CCL06_RS10485	COG0252	asparaginase activity
CCL06_RS10490	COG0616	signal peptide processing
CCL06_RS10495	COG0778	Nitroreductase
CCL06_RS10505	COG0709	Synthesizes selenophosphate from selenide and ATP
CCL06_RS10510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCL06_RS10525	COG0494	nUDIX hydrolase
CCL06_RS10530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCL06_RS10535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCL06_RS10540	COG2897	thiosulfate sulfurtransferase activity
CCL06_RS10545	COG4136	ATPase activity
CCL06_RS10550	COG4135	transport system, permease component
CCL06_RS10555	COG4134	Bacterial extracellular solute-binding protein
CCL06_RS10575	COG3138	arginine N-succinyltransferase
CCL06_RS10580	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS10585	COG3724	N-succinylarginine dihydrolase activity
CCL06_RS10595	COG3678	ATP-independent chaperone mediated protein folding
CCL06_RS10605	COG0322	excinuclease ABC activity
CCL06_RS10610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CCL06_RS10615	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCL06_RS10620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS10625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS10630	COG1447	Phosphotransferase system cellobiose-specific component IIA
CCL06_RS10635	COG2169	Transcriptional regulator
CCL06_RS10635	COG1917	Cupin 2, conserved barrel domain protein
CCL06_RS10640	COG1486	melibiose metabolic process
CCL06_RS10645	COG3394	polysaccharide catabolic process
CCL06_RS10650	COG0753	catalase activity
CCL06_RS10660	COG1823	symporter activity
CCL06_RS10665	COG1988	membrane-bound metal-dependent
CCL06_RS10670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCL06_RS10680	COG3001	Fructosamine kinase
CCL06_RS10690	COG1105	Belongs to the carbohydrate kinase PfkB family
CCL06_RS10695	COG3137	Salt-induced outer membrane protein
CCL06_RS10735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCL06_RS10740	COG0072	phenylalanine-tRNA ligase activity
CCL06_RS10740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCL06_RS10745	COG0776	regulation of translation
CCL06_RS10755	COG0386	Belongs to the glutathione peroxidase family
CCL06_RS10765	COG0791	NLP P60 protein
CCL06_RS10775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCL06_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS10785	COG2610	gluconate transmembrane transporter activity
CCL06_RS10795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCL06_RS10800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CCL06_RS10805	COG0583	DNA-binding transcription factor activity
CCL06_RS10815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS10820	COG4558	Periplasmic binding protein
CCL06_RS10825	COG3720	iron ion transport
CCL06_RS10835	COG4256	Hemin uptake protein
CCL06_RS10840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCL06_RS10845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CCL06_RS10850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCL06_RS10850	COG0574	Belongs to the PEP-utilizing enzyme family
CCL06_RS10855	COG2211	Major facilitator Superfamily
CCL06_RS10860	COG1472	Belongs to the glycosyl hydrolase 3 family
CCL06_RS10870	COG0628	permease
CCL06_RS10875	COG0247	lactate metabolic process
CCL06_RS10875	COG0277	FAD linked oxidase domain protein
CCL06_RS10880	COG2050	protein possibly involved in aromatic compounds catabolism
CCL06_RS10890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCL06_RS10900	COG3539	Fimbrial protein
CCL06_RS10905	COG3121	Chaperone
CCL06_RS10920	COG3539	Fimbrial protein
CCL06_RS10935	COG3383	formate dehydrogenase (NAD+) activity
CCL06_RS10955	COG2200	EAL domain
CCL06_RS10960	COG0789	Transcriptional regulator
CCL06_RS10975	COG0316	Belongs to the HesB IscA family
CCL06_RS10980	COG0719	Fe-S assembly protein
CCL06_RS10985	COG0396	ATPase activity
CCL06_RS10990	COG0719	Fe-S assembly protein
CCL06_RS11000	COG2166	iron-sulfur cluster assembly
CCL06_RS11005	COG1376	ErfK ybiS ycfS ynhG family protein
CCL06_RS11020	COG0626	cystathionine gamma-synthase activity
CCL06_RS11035	COG2011	ABC-type metal ion transport system permease component
CCL06_RS11040	COG1464	Belongs to the NlpA lipoprotein family
CCL06_RS11050	COG0765	amino acid transport
CCL06_RS11055	COG0765	amino acid transport
CCL06_RS11065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS11075	COG4191	Histidine kinase
CCL06_RS11095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCL06_RS11105	COG4529	Protein conserved in bacteria
CCL06_RS11120	COG0534	Mate efflux family protein
CCL06_RS11125	COG0307	riboflavin synthase, alpha
CCL06_RS11130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCL06_RS11135	COG2814	Major facilitator Superfamily
CCL06_RS11140	COG0583	DNA-binding transcription factor activity
CCL06_RS11160	COG2814	Major facilitator Superfamily
CCL06_RS11170	COG0791	NLP P60 protein
CCL06_RS11175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCL06_RS11180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCL06_RS11185	COG0346	lactoylglutathione lyase activity
CCL06_RS11190	COG1902	pentaerythritol trinitrate reductase activity
CCL06_RS11195	COG1309	transcriptional regulator
CCL06_RS11205	COG3313	Fe-S protein
CCL06_RS11210	COG4989	oxidoreductase activity
CCL06_RS11215	COG2032	superoxide dismutase activity
CCL06_RS11220	COG1289	transmembrane transporter activity
CCL06_RS11225	COG1566	PFAM secretion protein HlyD family protein
CCL06_RS11240	COG3706	GGDEF domain
CCL06_RS11250	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCL06_RS11255	COG3895	Periplasmic Protein
CCL06_RS11260	COG0259	pyridoxamine-phosphate oxidase activity
CCL06_RS11265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCL06_RS11270	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CCL06_RS11275	COG0625	glutathione transferase activity
CCL06_RS11280	COG3104	oligopeptide transport
CCL06_RS11285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCL06_RS11335	COG0673	inositol 2-dehydrogenase activity
CCL06_RS11340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCL06_RS11345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CCL06_RS11350	COG1263	PTS System
CCL06_RS11350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS11355	COG1609	Transcriptional regulator
CCL06_RS11360	COG5339	Protein conserved in bacteria
CCL06_RS11365	COG1482	cell wall glycoprotein biosynthetic process
CCL06_RS11370	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS11370	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS11375	COG0114	fumarate hydratase activity
CCL06_RS11385	COG2205	protein histidine kinase activity
CCL06_RS11390	COG0582	viral genome integration into host DNA
CCL06_RS11395	COG1403	HNH endonuclease
CCL06_RS11420	COG0745	RESPONSE REGULATOR receiver
CCL06_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS11430	COG0531	amino acid
CCL06_RS11445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CCL06_RS11450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CCL06_RS11470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCL06_RS11475	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CCL06_RS11480	COG1473	amidohydrolase
CCL06_RS11490	COG0583	DNA-binding transcription factor activity
CCL06_RS11495	COG2840	Smr protein MutS2
CCL06_RS11505	COG0667	Aldo Keto reductase
CCL06_RS11510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCL06_RS11525	COG0583	DNA-binding transcription factor activity
CCL06_RS11545	COG0583	DNA-binding transcription factor activity
CCL06_RS11550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCL06_RS11565	COG1403	HNH endonuclease
CCL06_RS11570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS11580	COG0628	permease
CCL06_RS11590	COG2076	Multidrug Resistance protein
CCL06_RS11600	COG5001	Diguanylate cyclase
CCL06_RS11605	COG3591	Belongs to the peptidase S1B family
CCL06_RS11620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CCL06_RS11625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS11630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCL06_RS11635	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS11640	COG1917	Cupin 2, conserved barrel domain protein
CCL06_RS11640	COG1396	sequence-specific DNA binding
CCL06_RS11645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CCL06_RS11650	COG0174	glutamine synthetase
CCL06_RS11665	COG2814	Major facilitator Superfamily
CCL06_RS11670	COG0583	DNA-binding transcription factor activity
CCL06_RS11675	COG1940	carbohydrate kinase activity
CCL06_RS11680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCL06_RS11750	COG3141	response to X-ray
CCL06_RS11760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS11780	COG0745	RESPONSE REGULATOR receiver
CCL06_RS11785	COG3713	MltA-interacting MipA family protein
CCL06_RS11805	COG3179	chitinase
CCL06_RS11820	COG3381	protein complex oligomerization
CCL06_RS11825	COG0243	molybdopterin cofactor binding
CCL06_RS11840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCL06_RS11850	COG1742	UPF0060 membrane protein
CCL06_RS11855	COG4948	Mandelate Racemase Muconate Lactonizing
CCL06_RS11860	COG1063	alcohol dehydrogenase
CCL06_RS11865	COG0477	Major facilitator Superfamily
CCL06_RS11870	COG0246	Mannitol dehydrogenase
CCL06_RS11880	COG1802	Transcriptional regulator
CCL06_RS11885	COG4221	oxidoreductase activity
CCL06_RS11895	COG5001	Diguanylate cyclase
CCL06_RS11905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCL06_RS11915	COG2911	Protein conserved in bacteria
CCL06_RS11925	COG3784	Protein of unknown function (DUF1318)
CCL06_RS11930	COG2207	Transcriptional regulator
CCL06_RS11935	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS11940	COG3706	GGDEF domain
CCL06_RS11950	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS11950	COG2030	dehydratase
CCL06_RS11955	COG3396	Phenylacetate-CoA oxygenase
CCL06_RS11960	COG3460	Phenylacetate-CoA oxygenase
CCL06_RS11965	COG3396	Phenylacetate-CoA oxygenase
CCL06_RS11970	COG2151	metal-sulfur cluster biosynthetic enzyme
CCL06_RS11975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCL06_RS11980	COG1024	Enoyl-CoA hydratase
CCL06_RS11985	COG1024	Enoyl-CoA hydratase
CCL06_RS11990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCL06_RS11995	COG2050	protein possibly involved in aromatic compounds catabolism
CCL06_RS12000	COG0183	Belongs to the thiolase family
CCL06_RS12005	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CCL06_RS12010	COG3327	negative regulation of DNA-templated transcription, initiation
CCL06_RS12015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCL06_RS12030	COG0386	Belongs to the glutathione peroxidase family
CCL06_RS12065	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCL06_RS12075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS12090	COG0583	DNA-binding transcription factor activity
CCL06_RS12095	COG1902	pentaerythritol trinitrate reductase activity
CCL06_RS12135	COG0300	oxidoreductase activity
CCL06_RS12150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCL06_RS12215	COG3122	Protein conserved in bacteria
CCL06_RS12220	COG0564	pseudouridine synthase activity
CCL06_RS12230	COG1643	Atp-dependent helicase
CCL06_RS12235	COG4122	O-methyltransferase activity
CCL06_RS12240	COG1538	Outer membrane efflux protein
CCL06_RS12255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCL06_RS12260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCL06_RS12265	COG3038	cytochrome b561
CCL06_RS12270	COG0673	inositol 2-dehydrogenase activity
CCL06_RS12275	COG1349	DNA-binding transcription factor activity
CCL06_RS12320	COG0840	transmembrane signaling receptor activity
CCL06_RS12325	COG4993	Dehydrogenase
CCL06_RS12330	COG3415	Transposase
CCL06_RS12330	COG2801	Transposase and inactivated derivatives
CCL06_RS12335	COG0583	DNA-binding transcription factor activity
CCL06_RS12340	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS12345	COG3111	PFAM Bacterial OB fold (BOF) protein
CCL06_RS12360	COG1546	Belongs to the CinA family
CCL06_RS12375	COG1294	oxidase, subunit
CCL06_RS12380	COG1271	oxidase subunit
CCL06_RS12385	COG3546	catalase activity
CCL06_RS12390	COG3685	Protein conserved in bacteria
CCL06_RS12400	COG3685	Protein conserved in bacteria
CCL06_RS12405	COG3729	General stress protein
CCL06_RS12410	COG5383	Protein conserved in bacteria
CCL06_RS12415	COG2272	Belongs to the type-B carboxylesterase lipase family
CCL06_RS12425	COG0436	Aminotransferase
CCL06_RS12440	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CCL06_RS12445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCL06_RS12450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCL06_RS12455	COG0500	methyltransferase
CCL06_RS12460	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCL06_RS12465	COG0747	negative chemotaxis
CCL06_RS12485	COG3135	benzoate transporter
CCL06_RS12490	COG1396	sequence-specific DNA binding
CCL06_RS12495	COG0826	peptidase U32
CCL06_RS12510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CCL06_RS12525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCL06_RS12545	COG1129	ABC transporter
CCL06_RS12555	COG3443	Belongs to the bacterial solute-binding protein 9 family
CCL06_RS12560	COG2814	Major facilitator Superfamily
CCL06_RS12565	COG0697	spore germination
CCL06_RS12580	COG1846	Transcriptional regulator
CCL06_RS12595	COG1846	Transcriptional regulator
CCL06_RS12605	COG2814	Major facilitator Superfamily
CCL06_RS12625	COG0583	DNA-binding transcription factor activity
CCL06_RS12630	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS12640	COG2066	Belongs to the glutaminase family
CCL06_RS12650	COG2199	diguanylate cyclase activity
CCL06_RS12655	COG3706	GGDEF domain
CCL06_RS12665	COG0246	Mannitol dehydrogenase
CCL06_RS12670	COG3781	membrane
CCL06_RS12695	COG0596	Alpha beta hydrolase
CCL06_RS12715	COG4106	trans-aconitate 2-methyltransferase activity
CCL06_RS12720	COG0494	nUDIX hydrolase
CCL06_RS12725	COG1349	DNA-binding transcription factor activity
CCL06_RS12745	COG0583	DNA-binding transcription factor activity
CCL06_RS12765	COG2814	Major facilitator Superfamily
CCL06_RS12770	COG1979	alcohol dehydrogenase
CCL06_RS12800	COG2801	Transposase and inactivated derivatives
CCL06_RS12810	COG2801	Transposase and inactivated derivatives
CCL06_RS12815	COG0667	Aldo Keto reductase
CCL06_RS12820	COG3386	PFAM SMP-30 Gluconolaconase
CCL06_RS12825	COG0667	Aldo Keto reductase
CCL06_RS12830	COG0667	Aldo Keto reductase
CCL06_RS12845	COG3550	peptidyl-serine autophosphorylation
CCL06_RS12870	COG0745	RESPONSE REGULATOR receiver
CCL06_RS12880	COG0583	DNA-binding transcription factor activity
CCL06_RS12885	COG2814	Major facilitator Superfamily
CCL06_RS12920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCL06_RS12930	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CCL06_RS12945	COG0583	DNA-binding transcription factor activity
CCL06_RS12950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCL06_RS12960	COG1366	Belongs to the anti-sigma-factor antagonist family
CCL06_RS13005	COG0784	Response regulator, receiver
CCL06_RS13005	COG2205	protein histidine kinase activity
CCL06_RS13005	COG5002	protein histidine kinase activity
CCL06_RS13015	COG4628	conserved protein (DUF2132)
CCL06_RS13020	COG1649	PFAM Uncharacterised BCR, COG1649
CCL06_RS13025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCL06_RS13060	COG0840	transmembrane signaling receptor activity
CCL06_RS13090	COG2200	EAL domain
CCL06_RS13105	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CCL06_RS13110	COG0747	negative chemotaxis
CCL06_RS13115	COG0601	transmembrane transport
CCL06_RS13120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS13125	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS13130	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS13135	COG1764	response to oxidative stress
CCL06_RS13165	COG0281	malic enzyme
CCL06_RS13170	COG3415	Transposase
CCL06_RS13170	COG2801	Transposase and inactivated derivatives
CCL06_RS13175	COG0488	(ABC) transporter
CCL06_RS13180	COG1064	alcohol dehydrogenase
CCL06_RS13190	COG0601	transmembrane transport
CCL06_RS13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS13205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS13215	COG2814	Major facilitator Superfamily
CCL06_RS13235	COG2864	formate dehydrogenase
CCL06_RS13240	COG0437	4 iron, 4 sulfur cluster binding
CCL06_RS13275	COG0583	DNA-binding transcription factor activity
CCL06_RS13330	COG0471	metal ion transport
CCL06_RS13335	COG1049	propionate catabolic process, 2-methylcitrate cycle
CCL06_RS13345	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CCL06_RS13365	COG3052	prosthetic group binding
CCL06_RS13375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCL06_RS13380	COG2814	Major facilitator Superfamily
CCL06_RS13385	COG2828	Protein conserved in bacteria
CCL06_RS13390	COG0583	DNA-binding transcription factor activity
CCL06_RS13395	COG1335	isochorismatase
CCL06_RS13405	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CCL06_RS13410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCL06_RS13420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCL06_RS13425	COG0640	Transcriptional regulator
CCL06_RS13440	COG3493	citrate carrier protein
CCL06_RS13450	COG1560	Kdo2-lipid A biosynthetic process
CCL06_RS13455	COG1942	4-Oxalocrotonate Tautomerase
CCL06_RS13460	COG0625	glutathione transferase activity
CCL06_RS13465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS13490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCL06_RS13565	COG1126	abc transporter atp-binding protein
CCL06_RS13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS13585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS13590	COG1473	amidohydrolase
CCL06_RS13595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS13625	COG4772	TonB-dependent receptor
CCL06_RS13630	COG1802	Transcriptional regulator
CCL06_RS13635	COG2130	NADP-dependent
CCL06_RS13645	COG1247	-acetyltransferase
CCL06_RS13650	COG3238	Protein conserved in bacteria
CCL06_RS13660	COG0747	negative chemotaxis
CCL06_RS13690	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS13695	COG1177	transmembrane transport
CCL06_RS13700	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCL06_RS13705	COG3842	ATPase activity
CCL06_RS13710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCL06_RS13715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCL06_RS13725	COG1271	oxidase subunit
CCL06_RS13730	COG1294	oxidase, subunit
CCL06_RS13740	COG3187	Heat shock protein
CCL06_RS13745	COG3042	response to heat
CCL06_RS13750	COG0674	pyruvate-flavodoxin oxidoreductase activity
CCL06_RS13750	COG1013	pyruvate-flavodoxin oxidoreductase activity
CCL06_RS13750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCL06_RS13750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CCL06_RS13755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCL06_RS13780	COG2200	EAL domain
CCL06_RS13795	COG1335	isochorismatase
CCL06_RS13800	COG0582	viral genome integration into host DNA
CCL06_RS13810	COG0513	Belongs to the DEAD box helicase family
CCL06_RS13825	COG0840	transmembrane signaling receptor activity
CCL06_RS13835	COG3706	GGDEF domain
CCL06_RS13840	COG0693	protein deglycase activity
CCL06_RS13965	COG4166	transmembrane transport
CCL06_RS13970	COG2866	Carboxypeptidase
CCL06_RS13975	COG4948	Mandelate Racemase Muconate Lactonizing
CCL06_RS13980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CCL06_RS13995	COG3768	UPF0283 membrane protein
CCL06_RS14000	COG3106	COG3106 Predicted ATPase
CCL06_RS14005	COG1609	Transcriptional regulator
CCL06_RS14015	COG3842	ATPase activity
CCL06_RS14020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCL06_RS14025	COG1554	hydrolase, family 65, central catalytic
CCL06_RS14030	COG0673	inositol 2-dehydrogenase activity
CCL06_RS14035	COG1082	Xylose isomerase domain protein TIM barrel
CCL06_RS14040	COG1063	alcohol dehydrogenase
CCL06_RS14045	COG0395	ABC-type sugar transport system, permease component
CCL06_RS14050	COG1175	transmembrane transport
CCL06_RS14055	COG1653	transport
CCL06_RS14060	COG0366	Alpha amylase catalytic
CCL06_RS14070	COG1983	PspC domain protein
CCL06_RS14080	COG1842	Phage shock protein A
CCL06_RS14085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CCL06_RS14100	COG4171	peptide transport system, permease
CCL06_RS14110	COG4172	Belongs to the ABC transporter superfamily
CCL06_RS14120	COG5002	protein histidine kinase activity
CCL06_RS14125	COG0745	RESPONSE REGULATOR receiver
CCL06_RS14140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS14145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCL06_RS14150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCL06_RS14150	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CCL06_RS14155	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CCL06_RS14160	COG5001	Diguanylate cyclase
CCL06_RS14165	COG1024	Enoyl-CoA hydratase
CCL06_RS14175	COG1349	DNA-binding transcription factor activity
CCL06_RS14185	COG0023	Translation Initiation Factor
CCL06_RS14190	COG0284	orotidine-5'-phosphate decarboxylase activity
CCL06_RS14195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CCL06_RS14200	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CCL06_RS14205	COG0671	phosphoesterase, PA-phosphatase related
CCL06_RS14215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CCL06_RS14250	COG0616	signal peptide processing
CCL06_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS14260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CCL06_RS14270	COG0009	L-threonylcarbamoyladenylate synthase
CCL06_RS14285	COG0512	Glutamine amidotransferase of anthranilate synthase
CCL06_RS14285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCL06_RS14300	COG0159	tryptophan synthase activity
CCL06_RS14305	COG2391	methyltransferase activity
CCL06_RS14310	COG0425	Belongs to the sulfur carrier protein TusA family
CCL06_RS14315	COG3047	cAMP biosynthetic process
CCL06_RS14320	COG0727	PFAM Uncharacterised protein family (UPF0153)
CCL06_RS14345	COG2350	Protein conserved in bacteria
CCL06_RS14355	COG1280	lysine exporter protein (LysE YggA)
CCL06_RS14370	COG3099	Belongs to the UPF0263 family
CCL06_RS14375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCL06_RS14380	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS14385	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS14395	COG0601	transmembrane transport
CCL06_RS14405	COG2095	MarC family integral membrane protein
CCL06_RS14410	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS14410	COG1454	alcohol dehydrogenase
CCL06_RS14415	COG1435	thymidine kinase activity
CCL06_RS14425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCL06_RS14430	COG0745	RESPONSE REGULATOR receiver
CCL06_RS14435	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCL06_RS14440	COG3012	SEC-C Motif Domain Protein
CCL06_RS14445	COG0788	formyltetrahydrofolate deformylase activity
CCL06_RS14460	COG1522	sequence-specific DNA binding
CCL06_RS14465	COG0697	spore germination
CCL06_RS14470	COG2181	nitrate reductase activity
CCL06_RS14475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CCL06_RS14480	COG1140	nitrate reductase beta subunit
CCL06_RS14485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CCL06_RS14490	COG2223	nitrite transmembrane transporter activity
CCL06_RS14495	COG3850	Histidine kinase
CCL06_RS14500	COG2197	response regulator
CCL06_RS14505	COG4932	domain protein
CCL06_RS14510	COG0243	molybdopterin cofactor binding
CCL06_RS14515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCL06_RS14515	COG2146	nitrite reductase [NAD(P)H] activity
CCL06_RS14520	COG1116	anion transmembrane transporter activity
CCL06_RS14530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCL06_RS14535	COG3707	response regulator
CCL06_RS14540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CCL06_RS14545	COG0840	transmembrane signaling receptor activity
CCL06_RS14555	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CCL06_RS14560	COG4572	Cation transport regulator
CCL06_RS14565	COG0387	Pfam Sodium calcium exchanger
CCL06_RS14590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCL06_RS14595	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CCL06_RS14600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCL06_RS14615	COG0659	secondary active sulfate transmembrane transporter activity
CCL06_RS14630	COG0193	aminoacyl-tRNA hydrolase activity
CCL06_RS14635	COG0012	GTP binding
CCL06_RS14790	COG3209	COG3209 Rhs family protein
CCL06_RS14805	COG3209	COG3209 Rhs family protein
CCL06_RS14815	COG3209	COG3209 Rhs family protein
CCL06_RS14850	COG1397	ADP-ribosylglycohydrolase
CCL06_RS14870	COG1397	ADP-ribosylglycohydrolase
CCL06_RS14900	COG0515	serine threonine protein kinase
CCL06_RS14960	COG3039	Transposase
CCL06_RS15040	COG0243	molybdopterin cofactor binding
CCL06_RS15045	COG0583	DNA-binding transcription factor activity
CCL06_RS15060	COG4977	sequence-specific DNA binding
CCL06_RS15070	COG2814	Major facilitator Superfamily
CCL06_RS15085	COG2211	Major facilitator Superfamily
CCL06_RS15100	COG4774	siderophore transport
CCL06_RS15115	COG0741	lytic transglycosylase activity
CCL06_RS15120	COG1619	proteins homologs of microcin C7 resistance protein MccF
CCL06_RS15125	COG3263	regulation of cellular component size
CCL06_RS15135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCL06_RS15140	COG2719	SpoVR family
CCL06_RS15150	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCL06_RS15165	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCL06_RS15170	COG3100	YcgL domain-containing protein
CCL06_RS15175	COG0850	regulation of cytokinetic process
CCL06_RS15180	COG2894	cell division
CCL06_RS15185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CCL06_RS15190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CCL06_RS15195	COG0318	PFAM AMP-dependent synthetase and ligase
CCL06_RS15200	COG3065	identical protein binding
CCL06_RS15210	COG1199	ATP-dependent helicase activity
CCL06_RS15215	COG0251	oxidation-reduction process
CCL06_RS15225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCL06_RS15235	COG1760	l-serine dehydratase
CCL06_RS15240	COG2200	EAL domain
CCL06_RS15245	COG1253	flavin adenine dinucleotide binding
CCL06_RS15255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS15255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS15260	COG3715	PTS system
CCL06_RS15265	COG3716	PTS system mannose fructose sorbose family IID component
CCL06_RS15270	COG4811	Protein of unknown function (DUF986)
CCL06_RS15275	COG1971	Probably functions as a manganese efflux pump
CCL06_RS15280	COG2226	methyltransferase
CCL06_RS15285	COG0768	penicillin binding
CCL06_RS15320	COG1414	Transcriptional regulator
CCL06_RS15325	COG2814	Major facilitator Superfamily
CCL06_RS15330	COG0501	Belongs to the peptidase M48B family
CCL06_RS15345	COG1956	GAF domain-containing protein
CCL06_RS15350	COG2995	paraquat-inducible protein a
CCL06_RS15355	COG3008	intermembrane lipid transfer
CCL06_RS15360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCL06_RS15360	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CCL06_RS15375	COG2990	Protein conserved in bacteria
CCL06_RS15385	COG1276	copper resistance
CCL06_RS15390	COG2372	response to copper ion
CCL06_RS15400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCL06_RS15405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCL06_RS15410	COG1770	oligopeptidase
CCL06_RS15415	COG2979	Protein of unknown function (DUF533)
CCL06_RS15425	COG0800	Aldolase
CCL06_RS15430	COG0129	dihydroxy-acid dehydratase activity
CCL06_RS15435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CCL06_RS15440	COG1737	Transcriptional regulator
CCL06_RS15450	COG1560	Kdo2-lipid A biosynthetic process
CCL06_RS15455	COG0739	heme binding
CCL06_RS15460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CCL06_RS15470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCL06_RS15475	COG2255	four-way junction helicase activity
CCL06_RS15480	COG0632	four-way junction helicase activity
CCL06_RS15495	COG0494	nUDIX hydrolase
CCL06_RS15510	COG1335	isochorismatase
CCL06_RS15515	COG1801	Protein of unknown function DUF72
CCL06_RS15520	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CCL06_RS15525	COG2226	methyltransferase
CCL06_RS15535	COG3142	Participates in the control of copper homeostasis
CCL06_RS15540	COG3102	Protein conserved in bacteria
CCL06_RS15545	COG0018	arginyl-trna synthetase
CCL06_RS15570	COG0745	RESPONSE REGULATOR receiver
CCL06_RS15585	COG0840	transmembrane signaling receptor activity
CCL06_RS15620	COG1301	dicarboxylic acid transport
CCL06_RS15660	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CCL06_RS15670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS15680	COG1879	ABC-type sugar transport system periplasmic component
CCL06_RS15690	COG1528	Iron-storage protein
CCL06_RS15695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CCL06_RS15715	COG1528	Iron-storage protein
CCL06_RS15720	COG0814	amino acid
CCL06_RS15725	COG3012	SEC-C Motif Domain Protein
CCL06_RS15725	COG3318	Belongs to the UPF0149 family
CCL06_RS15775	COG0463	Glycosyl transferase, family 2
CCL06_RS15820	COG2197	response regulator
CCL06_RS15830	COG2197	response regulator
CCL06_RS15835	COG1126	abc transporter atp-binding protein
CCL06_RS15840	COG0765	amino acid transport
CCL06_RS15850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS15875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CCL06_RS15890	COG0366	Alpha amylase catalytic
CCL06_RS15900	COG1677	Flagellar hook-basal body complex protein FliE
CCL06_RS15910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCL06_RS15920	COG1157	protein secretion by the type III secretion system
CCL06_RS15960	COG1987	bacterial-type flagellum assembly
CCL06_RS15970	COG2197	response regulator
CCL06_RS15995	COG5475	Uncharacterized small protein (DUF2158)
CCL06_RS16000	COG2354	Protein conserved in bacteria
CCL06_RS16005	COG0697	spore germination
CCL06_RS16010	COG3727	T/G mismatch-specific endonuclease activity
CCL06_RS16015	COG0270	DNA (cytosine-5-)-methyltransferase activity
CCL06_RS16020	COG1418	mRNA catabolic process
CCL06_RS16025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCL06_RS16035	COG3290	protein histidine kinase activity
CCL06_RS16040	COG4565	transcriptional regulatory protein
CCL06_RS16060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS16060	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CCL06_RS16070	COG3121	Chaperone
CCL06_RS16085	COG3121	Chaperone
CCL06_RS16090	COG3539	Fimbrial protein
CCL06_RS16115	COG0583	DNA-binding transcription factor activity
CCL06_RS16120	COG0835	chemotaxis
CCL06_RS16125	COG2198	Histidine kinase
CCL06_RS16125	COG0643	Histidine kinase
CCL06_RS16130	COG1360	Flagellar Motor Protein
CCL06_RS16135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CCL06_RS16150	COG1191	sigma factor activity
CCL06_RS16170	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCL06_RS16170	COG3951	Flagellar rod assembly protein muramidase FlgJ
CCL06_RS16175	COG1706	bacterial-type flagellum-dependent cell motility
CCL06_RS16180	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CCL06_RS16185	COG4786	Flagellar basal body rod
CCL06_RS16195	COG1749	Flagellar hook protein flgE
CCL06_RS16210	COG1815	bacterial-type flagellum-dependent cell motility
CCL06_RS16255	COG0840	transmembrane signaling receptor activity
CCL06_RS16310	COG1580	Controls the rotational direction of flagella during chemotaxis
CCL06_RS16330	COG1317	bacterial-type flagellum organization
CCL06_RS16345	COG1677	Flagellar hook-basal body complex protein FliE
CCL06_RS16350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCL06_RS16360	COG0745	RESPONSE REGULATOR receiver
CCL06_RS16365	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCL06_RS16370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCL06_RS16400	COG1605	Chorismate mutase
CCL06_RS16455	COG0582	viral genome integration into host DNA
CCL06_RS16460	COG2207	Transcriptional regulator
CCL06_RS16465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCL06_RS16470	COG1845	cytochrome c oxidase, subunit III
CCL06_RS16475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCL06_RS16480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCL06_RS16485	COG2814	Major facilitator Superfamily
CCL06_RS16520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCL06_RS16540	COG3451	type IV secretory pathway VirB4
CCL06_RS16560	COG3736	Type IV secretory pathway, component VirB8
CCL06_RS16565	COG3504	Conjugal transfer protein
CCL06_RS16620	COG0631	protein serine/threonine phosphatase activity
CCL06_RS16660	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CCL06_RS16665	COG0583	DNA-binding transcription factor activity
CCL06_RS16680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS16695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCL06_RS16710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCL06_RS16715	COG0475	glutathione-regulated potassium exporter activity
CCL06_RS16720	COG2814	Major facilitator Superfamily
CCL06_RS16745	COG1376	ErfK ybiS ycfS ynhG family protein
CCL06_RS16750	COG0477	Major facilitator Superfamily
CCL06_RS16755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCL06_RS16760	COG0006	proline dipeptidase activity
CCL06_RS16770	COG0534	Mate efflux family protein
CCL06_RS16790	COG1289	transmembrane transporter activity
CCL06_RS16795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CCL06_RS16805	COG2925	Exonuclease
CCL06_RS16810	COG0531	amino acid
CCL06_RS16815	COG0583	DNA-binding transcription factor activity
CCL06_RS16820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCL06_RS16825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCL06_RS16835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCL06_RS16845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCL06_RS16850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCL06_RS16855	COG0107	imidazoleglycerol-phosphate synthase activity
CCL06_RS16935	COG2089	acid synthase
CCL06_RS16945	COG1083	cytidylyl-transferase
CCL06_RS16950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCL06_RS16955	COG1086	Polysaccharide biosynthesis protein
CCL06_RS16970	COG0438	transferase activity, transferring glycosyl groups
CCL06_RS16975	COG2327	Polysaccharide pyruvyl transferase
CCL06_RS16980	COG2244	polysaccharide biosynthetic process
CCL06_RS16985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCL06_RS16990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCL06_RS17000	COG0297	glycogen (starch) synthase activity
CCL06_RS17005	COG1051	belongs to the nudix hydrolase family
CCL06_RS17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCL06_RS17015	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CCL06_RS17020	COG0110	maltose O-acetyltransferase activity
CCL06_RS17025	COG1216	Glycosyl transferase, family 2
CCL06_RS17035	COG0438	transferase activity, transferring glycosyl groups
CCL06_RS17040	COG1045	serine acetyltransferase
CCL06_RS17045	COG0463	Glycosyl transferase, family 2
CCL06_RS17050	COG0489	protein tyrosine kinase activity
CCL06_RS17050	COG3206	protein involved in exopolysaccharide biosynthesis
CCL06_RS17065	COG1253	flavin adenine dinucleotide binding
CCL06_RS17070	COG2982	Protein involved in outer membrane biogenesis
CCL06_RS17075	COG0717	Belongs to the dCTP deaminase family
CCL06_RS17085	COG3447	MASE1 domain protein
CCL06_RS17085	COG5001	Diguanylate cyclase
CCL06_RS17085	COG5002	protein histidine kinase activity
CCL06_RS17090	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CCL06_RS17095	COG0443	Heat shock 70 kDa protein
CCL06_RS17100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS17105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS17110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS17115	COG0477	Major facilitator Superfamily
CCL06_RS17120	COG2205	protein histidine kinase activity
CCL06_RS17125	COG0745	RESPONSE REGULATOR receiver
CCL06_RS17130	COG3422	double-strand break repair
CCL06_RS17135	COG0826	peptidase U32
CCL06_RS17145	COG1597	lipid kinase activity
CCL06_RS17150	COG1830	Aldolase
CCL06_RS17155	COG2211	Major facilitator Superfamily
CCL06_RS17160	COG1397	ADP-ribosylglycohydrolase
CCL06_RS17165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS17170	COG2188	Transcriptional regulator
CCL06_RS17175	COG0351	phosphomethylpyrimidine kinase
CCL06_RS17180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CCL06_RS17220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS17225	COG0076	glutamate decarboxylase activity
CCL06_RS17230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCL06_RS17235	COG0583	DNA-binding transcription factor activity
CCL06_RS17245	COG2252	PERMEase
CCL06_RS17250	COG3206	protein involved in exopolysaccharide biosynthesis
CCL06_RS17250	COG0489	protein tyrosine kinase activity
CCL06_RS17255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCL06_RS17265	COG5455	response to cobalt ion
CCL06_RS17275	COG0489	protein tyrosine kinase activity
CCL06_RS17285	COG4807	Protein conserved in bacteria
CCL06_RS17295	COG3275	phosphorelay sensor kinase activity
CCL06_RS17300	COG0789	Transcriptional regulator
CCL06_RS17310	COG1174	glycine betaine transport
CCL06_RS17315	COG1125	glycine betaine transport
CCL06_RS17320	COG1174	glycine betaine transport
CCL06_RS17325	COG1732	Glycine betaine
CCL06_RS17330	COG1472	Belongs to the glycosyl hydrolase 3 family
CCL06_RS17335	COG0277	FAD linked oxidase domain protein
CCL06_RS17345	COG1686	Belongs to the peptidase S11 family
CCL06_RS17355	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS17360	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS17365	COG1538	Outer membrane efflux protein
CCL06_RS17370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCL06_RS17380	COG1346	cytolysis
CCL06_RS17385	COG0295	cytidine deaminase activity
CCL06_RS17390	COG2949	membrane
CCL06_RS17395	COG0174	glutamine synthetase
CCL06_RS17405	COG1129	ABC transporter
CCL06_RS17425	COG2311	Membrane
CCL06_RS17435	COG0477	Major facilitator Superfamily
CCL06_RS17445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CCL06_RS17450	COG4771	TonB-dependent receptor
CCL06_RS17455	COG0833	amino acid
CCL06_RS17465	COG0583	DNA-binding transcription factor activity
CCL06_RS17470	COG2855	membrane
CCL06_RS17475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CCL06_RS17480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS17480	COG1522	sequence-specific DNA binding
CCL06_RS17485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCL06_RS17490	COG2313	pseudouridylate synthase activity
CCL06_RS17495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS17500	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CCL06_RS17500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCL06_RS17500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCL06_RS17505	COG1105	Belongs to the carbohydrate kinase PfkB family
CCL06_RS17525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCL06_RS17530	COG1312	Catalyzes the dehydration of D-mannonate
CCL06_RS17535	COG0246	Mannitol dehydrogenase
CCL06_RS17540	COG0523	cobalamin synthesis protein
CCL06_RS17545	COG0671	phosphoesterase, PA-phosphatase related
CCL06_RS17550	COG0791	NLP P60 protein
CCL06_RS17555	COG2200	EAL domain
CCL06_RS17560	COG4166	transmembrane transport
CCL06_RS17565	COG4174	ABC transporter (Permease)
CCL06_RS17570	COG4239	(ABC) transporter, permease
CCL06_RS17575	COG4172	Belongs to the ABC transporter superfamily
CCL06_RS17590	COG2814	Major facilitator Superfamily
CCL06_RS17595	COG1187	pseudouridine synthase activity
CCL06_RS17600	COG1061	Type III restriction enzyme res subunit
CCL06_RS17610	COG3081	Nucleoid-associated protein
CCL06_RS17615	COG3082	Protein of unknown function (DUF1414)
CCL06_RS17655	COG3182	Iron-regulated membrane protein
CCL06_RS17665	COG0579	oxidoreductase
CCL06_RS17670	COG0659	secondary active sulfate transmembrane transporter activity
CCL06_RS17675	COG2239	Acts as a magnesium transporter
CCL06_RS17680	COG4615	Cyclic peptide transporter
CCL06_RS17685	COG3145	DNA-N1-methyladenine dioxygenase activity
CCL06_RS17690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCL06_RS17690	COG2169	Transcriptional regulator
CCL06_RS17705	COG2198	Histidine kinase
CCL06_RS17705	COG0642	Histidine kinase
CCL06_RS17715	COG2205	protein histidine kinase activity
CCL06_RS17715	COG0784	Response regulator, receiver
CCL06_RS17725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCL06_RS17740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCL06_RS17745	COG0584	glycerophosphoryl diester phosphodiesterase
CCL06_RS17750	COG2271	Major facilitator Superfamily
CCL06_RS17755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CCL06_RS17760	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CCL06_RS17765	COG0247	lactate metabolic process
CCL06_RS17785	COG1441	menaquinone biosynthetic process
CCL06_RS17795	COG0596	Alpha beta hydrolase
CCL06_RS17800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CCL06_RS17805	COG1169	isochorismate synthase
CCL06_RS17810	COG4575	ribosome binding
CCL06_RS17815	COG2153	protein acetylation
CCL06_RS17820	COG1234	tRNA 3'-trailer cleavage
CCL06_RS17825	COG0835	chemotaxis
CCL06_RS17825	COG0784	Response regulator, receiver
CCL06_RS17830	COG1007	ATP synthesis coupled electron transport
CCL06_RS17835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCL06_RS17840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCL06_RS17845	COG0713	ATP synthesis coupled electron transport
CCL06_RS17850	COG0839	Belongs to the complex I subunit 6 family
CCL06_RS17860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCL06_RS17890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCL06_RS17895	COG0583	DNA-binding transcription factor activity
CCL06_RS17900	COG0436	Aminotransferase
CCL06_RS17910	COG0490	domain, Protein
CCL06_RS17910	COG0471	metal ion transport
CCL06_RS17915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCL06_RS17940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCL06_RS17945	COG3959	Transketolase, thiamine diphosphate binding domain
CCL06_RS17950	COG3037	sugar-specific permease SgaT UlaA
CCL06_RS17970	COG1609	Transcriptional regulator
CCL06_RS17980	COG0622	Phosphoesterase
CCL06_RS17985	COG0625	glutathione transferase activity
CCL06_RS17990	COG0625	glutathione transferase activity
CCL06_RS17995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCL06_RS18000	COG1090	epimerase
CCL06_RS18005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCL06_RS18010	COG4598	ABC transporter
CCL06_RS18015	COG4160	amino acid transport
CCL06_RS18025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS18035	COG0163	prenyltransferase activity
CCL06_RS18040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CCL06_RS18045	COG1286	toxin biosynthetic process
CCL06_RS18050	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CCL06_RS18055	COG0285	dihydrofolate synthase activity
CCL06_RS18065	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS18070	COG0101	tRNA pseudouridine synthase activity
CCL06_RS18075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCL06_RS18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCL06_RS18095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCL06_RS18100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCL06_RS18100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CCL06_RS18110	COG3101	peptidyl-lysine hydroxylation
CCL06_RS18115	COG0730	response to heat
CCL06_RS18125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCL06_RS18135	COG2840	Smr protein MutS2
CCL06_RS18140	COG2062	phosphohistidine phosphatase, SixA
CCL06_RS18145	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCL06_RS18145	COG1024	Enoyl-CoA hydratase
CCL06_RS18155	COG3691	Protein conserved in bacteria
CCL06_RS18165	COG2067	long-chain fatty acid transport protein
CCL06_RS18175	COG2116	formate transmembrane transporter activity
CCL06_RS18190	COG1560	Kdo2-lipid A biosynthetic process
CCL06_RS18205	COG0436	Aminotransferase
CCL06_RS18210	COG3275	phosphorelay sensor kinase activity
CCL06_RS18215	COG3279	Response regulator of the LytR AlgR family
CCL06_RS18220	COG0837	glucose binding
CCL06_RS18235	COG0667	Aldo Keto reductase
CCL06_RS18245	COG1914	H( )-stimulated, divalent metal cation uptake system
CCL06_RS18250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCL06_RS18255	COG2199	diguanylate cyclase activity
CCL06_RS18255	COG2200	EAL domain
CCL06_RS18270	COG3415	Transposase
CCL06_RS18275	COG3415	Transposase
CCL06_RS18280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCL06_RS18310	COG0583	DNA-binding transcription factor activity
CCL06_RS18315	COG0385	Bile acid
CCL06_RS18320	COG3530	Putative quorum-sensing-regulated virulence factor
CCL06_RS18330	COG3115	cell septum assembly
CCL06_RS18355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS18380	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCL06_RS18385	COG4208	sulfate ABC transporter
CCL06_RS18390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CCL06_RS18395	COG4150	thiosulfate binding
CCL06_RS18400	COG2837	iron assimilation
CCL06_RS18425	COG0408	coproporphyrinogen oxidase activity
CCL06_RS18440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCL06_RS18445	COG5342	invasion associated locus B
CCL06_RS18450	COG0494	nUDIX hydrolase
CCL06_RS18455	COG0493	'glutamate synthase
CCL06_RS18455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCL06_RS18465	COG3850	Histidine kinase
CCL06_RS18470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS18475	COG1393	Belongs to the ArsC family
CCL06_RS18480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCL06_RS18490	COG0400	carboxylic ester hydrolase activity
CCL06_RS18500	COG2321	neutral zinc metallopeptidase
CCL06_RS18510	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CCL06_RS18520	COG2716	regulation of RNA biosynthetic process
CCL06_RS18525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCL06_RS18530	COG0628	permease
CCL06_RS18535	COG4783	chaperone-mediated protein folding
CCL06_RS18540	COG1393	Belongs to the ArsC family
CCL06_RS18550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CCL06_RS18555	COG1446	asparaginase
CCL06_RS18560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCL06_RS18575	COG2233	PERMEase
CCL06_RS18580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCL06_RS18585	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS18595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCL06_RS18600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCL06_RS18615	COG2200	EAL domain
CCL06_RS18625	COG0583	DNA-binding transcription factor activity
CCL06_RS18645	COG3718	enzyme involved in inositol metabolism
CCL06_RS18655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS18660	COG0673	inositol 2-dehydrogenase activity
CCL06_RS18665	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS18680	COG0673	inositol 2-dehydrogenase activity
CCL06_RS18685	COG3962	Belongs to the TPP enzyme family
CCL06_RS18725	COG0517	IMP dehydrogenase activity
CCL06_RS18725	COG0516	GMP reductase activity
CCL06_RS18730	COG1570	exodeoxyribonuclease VII activity
CCL06_RS18745	COG1645	bacterial-type flagellum-dependent swarming motility
CCL06_RS18760	COG1160	GTP binding
CCL06_RS18770	COG2976	Protein conserved in bacteria
CCL06_RS18775	COG0124	histidyl-tRNA synthetase
CCL06_RS18785	COG1426	Protein conserved in bacteria
CCL06_RS18790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCL06_RS18800	COG4953	penicillin-binding protein 1C
CCL06_RS18805	COG2373	Large extracellular alpha-helical protein
CCL06_RS18810	COG2190	(PTS) system
CCL06_RS18810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS18810	COG1263	PTS System
CCL06_RS18820	COG2897	thiosulfate sulfurtransferase activity
CCL06_RS18835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCL06_RS18840	COG2975	iron-sulfur cluster assembly
CCL06_RS18845	COG0633	Ferredoxin
CCL06_RS18850	COG0443	Heat shock 70 kDa protein
CCL06_RS18855	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCL06_RS18860	COG0316	Belongs to the HesB IscA family
CCL06_RS18865	COG0822	iron-sulfur transferase activity
CCL06_RS18870	COG1104	cysteine desulfurase activity
CCL06_RS18875	COG1959	2 iron, 2 sulfur cluster binding
CCL06_RS18890	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CCL06_RS18895	COG3683	transport system, periplasmic component
CCL06_RS18900	COG3711	transcriptional antiterminator
CCL06_RS18905	COG2814	Major facilitator Superfamily
CCL06_RS18910	COG2259	Doxx family
CCL06_RS18920	COG1017	nitric oxide dioxygenase activity
CCL06_RS18920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCL06_RS18925	COG0347	Belongs to the P(II) protein family
CCL06_RS18930	COG2204	response regulator
CCL06_RS18935	COG3170	Tfp pilus assembly protein FimV
CCL06_RS18940	COG2205	protein histidine kinase activity
CCL06_RS18945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCL06_RS18945	COG0047	phosphoribosylformylglycinamidine synthase activity
CCL06_RS18955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CCL06_RS18965	COG0560	Phosphoserine phosphatase
CCL06_RS18970	COG1263	PTS System
CCL06_RS18970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS18975	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CCL06_RS18980	COG1737	Transcriptional regulator
CCL06_RS18985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCL06_RS18995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CCL06_RS19000	COG1381	Involved in DNA repair and RecF pathway recombination
CCL06_RS19020	COG0681	Belongs to the peptidase S26 family
CCL06_RS19030	COG3086	response to oxidative stress
CCL06_RS19040	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CCL06_RS19050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCL06_RS19055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CCL06_RS19060	COG0513	Belongs to the DEAD box helicase family
CCL06_RS19075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCL06_RS19085	COG3118	belongs to the thioredoxin family
CCL06_RS19090	COG3148	PFAM DTW domain containing protein
CCL06_RS19100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCL06_RS19105	COG5544	Lipoprotein
CCL06_RS19110	COG0477	Major facilitator Superfamily
CCL06_RS19140	COG0542	response to heat
CCL06_RS19155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCL06_RS19160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCL06_RS19165	COG1605	Chorismate mutase
CCL06_RS19165	COG0077	Prephenate dehydratase
CCL06_RS19175	COG1605	Chorismate mutase
CCL06_RS19175	COG0287	Prephenate dehydrogenase
CCL06_RS19180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCL06_RS19195	COG2199	diguanylate cyclase activity
CCL06_RS19200	COG2885	chlorophyll binding
CCL06_RS19225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCL06_RS19235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCL06_RS19240	COG4137	Cytochrome C assembly protein
CCL06_RS19245	COG4536	flavin adenine dinucleotide binding
CCL06_RS19255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCL06_RS19260	COG0497	DNA recombination
CCL06_RS19275	COG2867	negative regulation of translational initiation
CCL06_RS19320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCL06_RS19320	COG2169	Transcriptional regulator
CCL06_RS19375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS19395	COG3549	Plasmid maintenance system killer
CCL06_RS19400	COG3093	addiction module antidote protein HigA
CCL06_RS19420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCL06_RS19425	COG0583	DNA-binding transcription factor activity
CCL06_RS19435	COG2226	methyltransferase
CCL06_RS19440	COG0402	S-adenosylhomocysteine deaminase activity
CCL06_RS19445	COG0549	Belongs to the carbamate kinase family
CCL06_RS19455	COG1304	FMN binding
CCL06_RS19460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CCL06_RS19465	COG0666	response to abiotic stimulus
CCL06_RS19470	COG0583	DNA-binding transcription factor activity
CCL06_RS19475	COG0401	homolog of Blt101
CCL06_RS19480	COG0640	Transcriptional regulator
CCL06_RS19485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCL06_RS19510	COG4575	ribosome binding
CCL06_RS19520	COG1780	Probably involved in ribonucleotide reductase function
CCL06_RS19525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCL06_RS19535	COG4175	Glycine betaine
CCL06_RS19540	COG4176	ABC-type proline glycine betaine transport system permease component
CCL06_RS19550	COG3415	Transposase
CCL06_RS19550	COG2801	Transposase and inactivated derivatives
CCL06_RS19555	COG2814	Major facilitator Superfamily
CCL06_RS19565	COG1566	PFAM secretion protein HlyD family protein
CCL06_RS19570	COG2814	Major facilitator Superfamily
CCL06_RS19575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCL06_RS19590	COG2918	glutathione biosynthetic process
CCL06_RS19595	COG1238	metal cluster binding
CCL06_RS19600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCL06_RS19630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CCL06_RS19635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCL06_RS19650	COG1546	Belongs to the CinA family
CCL06_RS19655	COG0803	Belongs to the bacterial solute-binding protein 9 family
CCL06_RS19660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCL06_RS19670	COG2951	lytic endotransglycosylase activity
CCL06_RS19675	COG3730	PTS system glucitol sorbitol-specific
CCL06_RS19680	COG3732	PTS system glucitol sorbitol-specific
CCL06_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS19695	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS19700	COG1349	DNA-binding transcription factor activity
CCL06_RS19705	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCL06_RS19705	COG0517	IMP dehydrogenase activity
CCL06_RS19710	COG3604	Transcriptional regulator
CCL06_RS19715	COG0426	domain, Protein
CCL06_RS19715	COG1773	rubredoxin
CCL06_RS19720	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCL06_RS19730	COG4533	DNA binding
CCL06_RS19735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CCL06_RS19740	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CCL06_RS19745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCL06_RS19750	COG1609	Transcriptional regulator
CCL06_RS19755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS19755	COG1263	PTS System
CCL06_RS19760	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS19765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CCL06_RS19775	COG3260	NADH ubiquinone oxidoreductase 20
CCL06_RS19780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCL06_RS19785	COG3261	NADH dehydrogenase
CCL06_RS19785	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CCL06_RS19790	COG0650	Formate hydrogenlyase subunit 4
CCL06_RS19795	COG0651	ATP synthesis coupled electron transport
CCL06_RS19800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCL06_RS19810	COG0375	protein maturation
CCL06_RS19815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCL06_RS19820	COG0298	carbon dioxide binding
CCL06_RS19825	COG0409	Hydrogenase expression formation protein
CCL06_RS19830	COG0309	Hydrogenase expression formation protein (HypE)
CCL06_RS19850	COG1120	ATPase activity
CCL06_RS19875	COG3710	Transcriptional regulator
CCL06_RS19880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCL06_RS19890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCL06_RS19895	COG0163	prenyltransferase activity
CCL06_RS19910	COG1388	LysM domain
CCL06_RS19910	COG4942	peptidase
CCL06_RS19925	COG0585	pseudouridine synthase activity
CCL06_RS19935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCL06_RS19940	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCL06_RS19950	COG0529	Catalyzes the synthesis of activated sulfate
CCL06_RS19970	COG2234	aminopeptidase activity
CCL06_RS19980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCL06_RS19985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCL06_RS19990	COG0720	synthase
CCL06_RS19995	COG0602	queuosine metabolic process
CCL06_RS20000	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CCL06_RS20005	COG1263	PTS System
CCL06_RS20005	COG2190	(PTS) system
CCL06_RS20005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCL06_RS20010	COG1737	Transcriptional regulator
CCL06_RS20030	COG3956	TIGRFAM MazG family protein
CCL06_RS20035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCL06_RS20040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCL06_RS20045	COG2205	protein histidine kinase activity
CCL06_RS20045	COG3437	response regulator, receiver
CCL06_RS20045	COG3850	Histidine kinase
CCL06_RS20045	COG4999	Histidine kinase
CCL06_RS20050	COG1929	Belongs to the glycerate kinase type-1 family
CCL06_RS20055	COG4948	Mandelate Racemase Muconate Lactonizing
CCL06_RS20060	COG4948	Mandelate Racemase Muconate Lactonizing
CCL06_RS20065	COG2271	Major facilitator Superfamily
CCL06_RS20075	COG0716	FMN binding
CCL06_RS20080	COG0564	pseudouridine synthase activity
CCL06_RS20085	COG3098	single-species biofilm formation
CCL06_RS20100	COG1611	Belongs to the LOG family
CCL06_RS20105	COG0814	amino acid
CCL06_RS20110	COG1760	l-serine dehydratase
CCL06_RS20120	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CCL06_RS20125	COG2363	Small membrane protein
CCL06_RS20130	COG0583	DNA-binding transcription factor activity
CCL06_RS20140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCL06_RS20145	COG2166	iron-sulfur cluster assembly
CCL06_RS20150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCL06_RS20155	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CCL06_RS20165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCL06_RS20170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCL06_RS20170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCL06_RS20175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCL06_RS20180	COG1074	ATP-dependent DNA helicase activity
CCL06_RS20190	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CCL06_RS20195	COG4967	type IV pilus modification protein PilV
CCL06_RS20205	COG4795	General secretion pathway protein
CCL06_RS20210	COG2165	general secretion pathway protein
CCL06_RS20215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCL06_RS20220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCL06_RS20230	COG0494	nUDIX hydrolase
CCL06_RS20235	COG3066	DNA modification
CCL06_RS20250	COG0477	Major facilitator Superfamily
CCL06_RS20255	COG0204	Acyl-transferase
CCL06_RS20255	COG0318	PFAM AMP-dependent synthetase and ligase
CCL06_RS20260	COG1609	Transcriptional regulator
CCL06_RS20270	COG1609	Transcriptional regulator
CCL06_RS20280	COG0583	DNA-binding transcription factor activity
CCL06_RS20285	COG1794	racemase activity, acting on amino acids and derivatives
CCL06_RS20290	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CCL06_RS20295	COG2814	Major facilitator Superfamily
CCL06_RS20300	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS20310	COG0183	Belongs to the thiolase family
CCL06_RS20325	COG0814	amino acid
CCL06_RS20340	COG2388	GCN5-related N-acetyl-transferase
CCL06_RS20345	COG3592	Divergent 4Fe-4S mono-cluster
CCL06_RS20355	COG4565	transcriptional regulatory protein
CCL06_RS20370	COG3842	ATPase activity
CCL06_RS20415	COG4942	peptidase
CCL06_RS20420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CCL06_RS20425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCL06_RS20435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCL06_RS20445	COG4974	Belongs to the 'phage' integrase family
CCL06_RS20465	COG0354	folic acid binding
CCL06_RS20470	COG1272	protein, Hemolysin III
CCL06_RS20475	COG1737	Transcriptional regulator
CCL06_RS20480	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS20490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCL06_RS20490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCL06_RS20500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CCL06_RS20505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCL06_RS20510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCL06_RS20515	COG0006	proline dipeptidase activity
CCL06_RS20530	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CCL06_RS20540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCL06_RS20545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCL06_RS20560	COG0583	DNA-binding transcription factor activity
CCL06_RS20565	COG2968	Membrane
CCL06_RS20570	COG1279	arginine transmembrane transporter activity
CCL06_RS20575	COG0668	transmembrane transport
CCL06_RS20580	COG0191	fructose-bisphosphate aldolase activity
CCL06_RS20590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCL06_RS20595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCL06_RS20600	COG0501	Belongs to the peptidase M48B family
CCL06_RS20615	COG1166	arginine decarboxylase activity
CCL06_RS20635	COG2814	Major facilitator Superfamily
CCL06_RS20640	COG3091	SprT-like family
CCL06_RS20645	COG2356	endonuclease I
CCL06_RS20650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCL06_RS20665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCL06_RS20670	COG2805	Type II/IV secretion system protein
CCL06_RS20675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCL06_RS20680	COG0762	integral membrane protein
CCL06_RS20685	COG1872	DUF167
CCL06_RS20695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCL06_RS20700	COG2852	Protein conserved in bacteria
CCL06_RS20715	COG3171	Protein conserved in bacteria
CCL06_RS20725	COG1194	a g-specific adenine glycosylase
CCL06_RS20735	COG0741	lytic transglycosylase activity
CCL06_RS20740	COG2801	Transposase and inactivated derivatives
CCL06_RS20740	COG3415	Transposase
CCL06_RS20745	COG2211	Major facilitator Superfamily
CCL06_RS20750	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CCL06_RS20770	COG3052	prosthetic group binding
CCL06_RS20780	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCL06_RS20785	COG3493	citrate carrier protein
CCL06_RS20800	COG3415	Transposase
CCL06_RS20800	COG2801	Transposase and inactivated derivatives
CCL06_RS20805	COG1982	Orn Lys Arg decarboxylase major
CCL06_RS20810	COG1811	Na channel or pump
CCL06_RS20825	COG5002	protein histidine kinase activity
CCL06_RS20830	COG2197	response regulator
CCL06_RS20850	COG0457	Tetratricopeptide repeat
CCL06_RS20855	COG0726	polysaccharide deacetylase
CCL06_RS20855	COG1649	PFAM Uncharacterised BCR, COG1649
CCL06_RS20860	COG1215	transferase activity, transferring glycosyl groups
CCL06_RS20870	COG0754	glutathionylspermidine amidase activity
CCL06_RS20875	COG4608	Belongs to the ABC transporter superfamily
CCL06_RS20880	COG0444	Belongs to the ABC transporter superfamily
CCL06_RS20885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCL06_RS20890	COG0601	transmembrane transport
CCL06_RS20900	COG0625	glutathione transferase activity
CCL06_RS20945	COG0840	transmembrane signaling receptor activity
CCL06_RS20950	COG0667	Aldo Keto reductase
CCL06_RS20955	COG3415	Transposase
CCL06_RS20955	COG2801	Transposase and inactivated derivatives
CCL06_RS20960	COG2862	Uncharacterized protein family, UPF0114
CCL06_RS20980	COG0840	transmembrane signaling receptor activity
CCL06_RS20985	COG0848	biopolymer transport protein
CCL06_RS21000	COG0626	cystathionine gamma-synthase activity
CCL06_RS21005	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS21010	COG2207	Transcriptional regulator
CCL06_RS21015	COG1979	alcohol dehydrogenase
CCL06_RS21030	COG1032	radical SAM domain protein
CCL06_RS21110	COG3436	PFAM IS66 Orf2 family protein
CCL06_RS21130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCL06_RS21145	COG1595	DNA-templated transcription, initiation
CCL06_RS21150	COG3712	iron ion homeostasis
CCL06_RS21155	COG4772	TonB-dependent receptor
CCL06_RS21160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CCL06_RS21165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS21170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS21175	COG1120	ATPase activity
CCL06_RS21180	COG3436	PFAM IS66 Orf2 family protein
CCL06_RS21200	COG1609	Transcriptional regulator
CCL06_RS21210	COG2223	nitrite transmembrane transporter activity
CCL06_RS21215	COG0110	maltose O-acetyltransferase activity
CCL06_RS21265	COG1032	radical SAM domain protein
CCL06_RS21270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCL06_RS21290	COG3111	PFAM Bacterial OB fold (BOF) protein
CCL06_RS21305	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCL06_RS21310	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CCL06_RS21325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS21330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCL06_RS21335	COG1120	ATPase activity
CCL06_RS21340	COG4774	siderophore transport
CCL06_RS21345	COG0187	DNA topoisomerase II activity
CCL06_RS21350	COG3150	esterase
CCL06_RS21355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CCL06_RS21360	COG3151	Protein conserved in bacteria
CCL06_RS21365	COG0494	nUDIX hydrolase
CCL06_RS21380	COG0754	glutathionylspermidine amidase activity
CCL06_RS21385	COG3384	dioxygenase
CCL06_RS21395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCL06_RS21405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CCL06_RS21405	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CCL06_RS21415	COG3025	triphosphatase activity
CCL06_RS21425	COG4991	sh3 domain protein
CCL06_RS21430	COG0617	tRNA 3'-terminal CCA addition
CCL06_RS21440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCL06_RS21450	COG0477	Major facilitator Superfamily
CCL06_RS21455	COG0829	nickel cation binding
CCL06_RS21460	COG0831	urea catabolic process
CCL06_RS21465	COG0832	Belongs to the urease beta subunit family
CCL06_RS21470	COG0804	urea catabolic process
CCL06_RS21475	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CCL06_RS21485	COG0830	nickel cation binding
CCL06_RS21490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCL06_RS21515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCL06_RS21520	COG0358	DNA primase activity
CCL06_RS21535	COG3663	DNA glycosylase
CCL06_RS21625	COG4974	Belongs to the 'phage' integrase family
CCL06_RS21660	COG2375	cellular response to nickel ion
CCL06_RS21665	COG1695	Transcriptional regulator
CCL06_RS21670	COG0840	transmembrane signaling receptor activity
CCL06_RS21675	COG0840	transmembrane signaling receptor activity
CCL06_RS21680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCL06_RS21695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CCL06_RS21700	COG1830	Aldolase
CCL06_RS21705	COG1879	ABC-type sugar transport system periplasmic component
CCL06_RS21710	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS21715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS21720	COG1129	ABC transporter
CCL06_RS21725	COG2390	Transcriptional regulator
CCL06_RS21730	COG1070	Carbohydrate kinase
CCL06_RS21735	COG1902	pentaerythritol trinitrate reductase activity
CCL06_RS21735	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCL06_RS21745	COG1451	nucleotide metabolic process
CCL06_RS21750	COG0673	inositol 2-dehydrogenase activity
CCL06_RS21755	COG0861	Integral membrane protein TerC family
CCL06_RS21765	COG2721	sulfolactate sulfo-lyase activity
CCL06_RS21780	COG2271	Major facilitator Superfamily
CCL06_RS21785	COG2186	Transcriptional regulator
CCL06_RS21790	COG0586	Pfam SNARE associated Golgi protein
CCL06_RS21800	COG1422	Protein of unknown function (DUF1090)
CCL06_RS21805	COG4575	ribosome binding
CCL06_RS21810	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CCL06_RS21820	COG2259	Doxx family
CCL06_RS21825	COG0435	Glutathione S-transferase
CCL06_RS21830	COG3152	Membrane
CCL06_RS21835	COG0583	DNA-binding transcription factor activity
CCL06_RS21840	COG1741	Belongs to the pirin family
CCL06_RS21865	COG1882	Formate acetyltransferase
CCL06_RS21870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCL06_RS21875	COG0814	amino acid
CCL06_RS21880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCL06_RS21885	COG0583	DNA-binding transcription factor activity
CCL06_RS21895	COG2084	Dehydrogenase
CCL06_RS21905	COG2721	sulfolactate sulfo-lyase activity
CCL06_RS21920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS21925	COG3414	Phosphotransferase system galactitol-specific IIB component
CCL06_RS21930	COG3775	system Galactitol-specific IIC component
CCL06_RS21935	COG1063	alcohol dehydrogenase
CCL06_RS21950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CCL06_RS21960	COG3107	peptidoglycan biosynthetic process
CCL06_RS21965	COG0792	nuclease activity
CCL06_RS21970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CCL06_RS21975	COG2823	Periplasmic or secreted lipoprotein
CCL06_RS21980	COG0701	Predicted permease
CCL06_RS21985	COG0702	epimerase
CCL06_RS21990	COG0693	protein deglycase activity
CCL06_RS21995	COG3787	Belongs to the UPF0306 family
CCL06_RS22000	COG2827	Endonuclease containing a URI domain
CCL06_RS22005	COG3153	acetyltransferase
CCL06_RS22010	COG3154	lipid carrier protein
CCL06_RS22015	COG0826	peptidase U32
CCL06_RS22020	COG0826	peptidase U32
CCL06_RS22025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCL06_RS22030	COG0814	amino acid
CCL06_RS22035	COG0513	Belongs to the DEAD box helicase family
CCL06_RS22050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCL06_RS22055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCL06_RS22060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCL06_RS22085	COG0137	argininosuccinate synthase activity
CCL06_RS22095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCL06_RS22100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCL06_RS22105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCL06_RS22110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCL06_RS22115	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CCL06_RS22120	COG1534	Rna-binding protein
CCL06_RS22130	COG2027	D-alanyl-D-alanine carboxypeptidase
CCL06_RS22135	COG0745	RESPONSE REGULATOR receiver
CCL06_RS22140	COG0642	Histidine kinase
CCL06_RS22145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCL06_RS22150	COG0697	spore germination
CCL06_RS22160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCL06_RS22165	COG0142	geranyltranstransferase activity
CCL06_RS22170	COG3423	Transcriptional regulator
CCL06_RS22175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCL06_RS22180	COG5007	Belongs to the BolA IbaG family
CCL06_RS22185	COG3113	response to antibiotic
CCL06_RS22190	COG2854	intermembrane phospholipid transfer
CCL06_RS22195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCL06_RS22200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCL06_RS22205	COG1127	ABC transporter
CCL06_RS22210	COG0530	calcium, potassium:sodium antiporter activity
CCL06_RS22220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCL06_RS22225	COG3117	lipopolysaccharide transmembrane transporter activity
CCL06_RS22230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CCL06_RS22235	COG1137	ATPase activity
CCL06_RS22240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CCL06_RS22260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCL06_RS22270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CCL06_RS22275	COG2198	Histidine kinase
CCL06_RS22275	COG5002	protein histidine kinase activity
CCL06_RS22275	COG0784	Response regulator, receiver
CCL06_RS22280	COG0795	lipopolysaccharide-transporting ATPase activity
CCL06_RS22285	COG0795	lipopolysaccharide-transporting ATPase activity
CCL06_RS22295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCL06_RS22300	COG2927	DNA polymerase III (CHI subunit)
CCL06_RS22315	COG1064	alcohol dehydrogenase
CCL06_RS22325	COG0433	COG0433 Predicted ATPase
CCL06_RS22330	COG1242	4 iron, 4 sulfur cluster binding
CCL06_RS22340	COG0069	glutamate synthase activity
CCL06_RS22340	COG0067	glutamate synthase
CCL06_RS22340	COG0070	glutamate synthase
CCL06_RS22345	COG0493	'glutamate synthase
CCL06_RS22350	COG2969	positive regulation of protein catabolic process
CCL06_RS22355	COG0625	glutathione transferase activity
CCL06_RS22370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCL06_RS22385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCL06_RS22390	COG3105	Protein conserved in bacteria
CCL06_RS22395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCL06_RS22400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCL06_RS22405	COG0039	L-malate dehydrogenase activity
CCL06_RS22410	COG1438	arginine binding
CCL06_RS22425	COG2732	(Barnase) inhibitor
CCL06_RS22430	COG1012	belongs to the aldehyde dehydrogenase family
CCL06_RS22435	COG1289	transmembrane transporter activity
CCL06_RS22450	COG0583	DNA-binding transcription factor activity
CCL06_RS22455	COG3477	response to acidic pH
CCL06_RS22460	COG0312	modulator of DNA gyrase
CCL06_RS22465	COG3164	Protein of unknown function
CCL06_RS22480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CCL06_RS22485	COG1792	Involved in formation and maintenance of cell shape
CCL06_RS22490	COG1077	Cell shape determining protein MreB Mrl
CCL06_RS22500	COG2199	diguanylate cyclase activity
CCL06_RS22500	COG2200	EAL domain
CCL06_RS22505	COG0604	alcohol dehydrogenase
CCL06_RS22515	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CCL06_RS22520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCL06_RS22525	COG0511	ligase activity, forming carbon-carbon bonds
CCL06_RS22530	COG0439	Biotin carboxylase
CCL06_RS22535	COG3924	membrane
CCL06_RS22540	COG4145	pantothenate transmembrane transporter activity
CCL06_RS22545	COG2264	protein methyltransferase activity
CCL06_RS22575	COG1309	transcriptional regulator
CCL06_RS22580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS22585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCL06_RS22595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCL06_RS22600	COG4597	amino acid ABC transporter
CCL06_RS22605	COG0765	amino acid transport
CCL06_RS22610	COG1126	abc transporter atp-binding protein
CCL06_RS22655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCL06_RS22665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCL06_RS22670	COG0009	L-threonylcarbamoyladenylate synthase
CCL06_RS22675	COG0551	DNA topoisomerase type I activity
CCL06_RS22680	COG2922	Belongs to the Smg family
CCL06_RS22685	COG0758	DNA mediated transformation
CCL06_RS22690	COG0242	peptide deformylase activity
CCL06_RS22700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCL06_RS22700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCL06_RS22715	COG3036	rescue of stalled ribosome
CCL06_RS22720	COG0789	Transcriptional regulator
CCL06_RS22735	COG0202	RNA polymerase activity
CCL06_RS22745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCL06_RS22760	COG0201	protein transport
CCL06_RS22770	COG1841	ribosomal large subunit assembly
CCL06_RS22785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCL06_RS22790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCL06_RS22825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCL06_RS22865	COG0051	transcription antitermination factor activity, RNA binding
CCL06_RS22875	COG3409	Peptidoglycan-binding domain 1 protein
CCL06_RS22875	COG3267	Type II secretory pathway component ExeA
CCL06_RS22880	COG3031	protein transport across the cell outer membrane
CCL06_RS22885	COG1450	Type ii and iii secretion system protein
CCL06_RS22890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCL06_RS22895	COG1459	type II secretion system
CCL06_RS22900	COG2165	general secretion pathway protein
CCL06_RS22905	COG2165	general secretion pathway protein
CCL06_RS22910	COG2165	general secretion pathway protein
CCL06_RS22915	COG4795	General secretion pathway protein
CCL06_RS22920	COG3156	type II secretion system protein K
CCL06_RS22935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCL06_RS22950	COG3979	chitinase
CCL06_RS22975	COG2168	tRNA wobble position uridine thiolation
CCL06_RS22980	COG2923	Belongs to the DsrF TusC family
CCL06_RS22985	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CCL06_RS22990	COG2964	Protein conserved in bacteria
CCL06_RS22995	COG0545	Peptidyl-prolyl cis-trans isomerase
CCL06_RS23005	COG1047	Peptidyl-prolyl cis-trans
CCL06_RS23010	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CCL06_RS23015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCL06_RS23015	COG0475	glutathione-regulated potassium exporter activity
CCL06_RS23020	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCL06_RS23030	COG0488	(ABC) transporter
CCL06_RS23035	COG0429	hydrolase of the alpha beta-hydrolase fold
CCL06_RS23040	COG3089	Belongs to the UPF0270 family
CCL06_RS23045	COG3954	Phosphoribulokinase
CCL06_RS23055	COG1765	OsmC-like protein
CCL06_RS23065	COG1289	transmembrane transporter activity
CCL06_RS23080	COG2184	nucleotidyltransferase activity
CCL06_RS23090	COG0738	Major facilitator superfamily
CCL06_RS23095	COG0402	S-adenosylhomocysteine deaminase activity
CCL06_RS23100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCL06_RS23110	COG1648	precorrin-2 dehydrogenase activity
CCL06_RS23110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCL06_RS23120	COG0180	Tryptophanyl-tRNA synthetase
CCL06_RS23130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCL06_RS23135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CCL06_RS23140	COG3266	domain, Protein
CCL06_RS23145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCL06_RS23150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCL06_RS23160	COG4796	Type ii and iii secretion system protein
CCL06_RS23185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CCL06_RS23190	COG0494	nUDIX hydrolase
CCL06_RS23205	COG1011	Hydrolase
CCL06_RS23210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCL06_RS23215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCL06_RS23220	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CCL06_RS23235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCL06_RS23240	COG2183	response to ionizing radiation
CCL06_RS23245	COG1918	ferrous iron import across plasma membrane
CCL06_RS23270	COG1040	competence protein
CCL06_RS23280	COG2610	gluconate transmembrane transporter activity
CCL06_RS23285	COG1640	4-alpha-glucanotransferase
CCL06_RS23290	COG0058	SHG alpha-glucan phosphorylase activity
CCL06_RS23295	COG2909	trisaccharide binding
CCL06_RS23300	COG1349	DNA-binding transcription factor activity
CCL06_RS23305	COG0705	Rhomboid family
CCL06_RS23310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCL06_RS23315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CCL06_RS23320	COG2801	Transposase and inactivated derivatives
CCL06_RS23320	COG3415	Transposase
CCL06_RS23325	COG0058	SHG alpha-glucan phosphorylase activity
CCL06_RS23330	COG0297	glycogen (starch) synthase activity
CCL06_RS23335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CCL06_RS23340	COG1523	belongs to the glycosyl hydrolase 13 family
CCL06_RS23345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCL06_RS23350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCL06_RS23355	COG2095	MarC family integral membrane protein
CCL06_RS23360	COG0425	Belongs to the sulfur carrier protein TusA family
CCL06_RS23365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CCL06_RS23375	COG0477	Major facilitator Superfamily
CCL06_RS23380	COG0628	permease
CCL06_RS23425	COG3479	Phenolic acid decarboxylase
CCL06_RS23435	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS23440	COG0791	NLP P60 protein
CCL06_RS23465	COG2205	protein histidine kinase activity
CCL06_RS23470	COG0745	RESPONSE REGULATOR receiver
CCL06_RS23475	COG1276	copper resistance
CCL06_RS23480	COG2372	response to copper ion
CCL06_RS23485	COG3667	copper resistance
CCL06_RS23490	COG2132	Multicopper oxidase
CCL06_RS23500	COG0739	heme binding
CCL06_RS23530	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCL06_RS23595	COG2081	HI0933 family
CCL06_RS23600	COG0306	phosphate transporter
CCL06_RS23615	COG0589	response to stress
CCL06_RS23620	COG0742	ribosomal rna small subunit methyltransferase
CCL06_RS23625	COG0339	signal peptide processing
CCL06_RS23630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCL06_RS23635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCL06_RS23645	COG2801	Transposase and inactivated derivatives
CCL06_RS23645	COG3415	Transposase
CCL06_RS23665	COG2197	response regulator
CCL06_RS23670	COG1028	Short-chain dehydrogenase reductase Sdr
CCL06_RS23675	COG0583	DNA-binding transcription factor activity
CCL06_RS23680	COG1295	ribonuclease BN
CCL06_RS23685	COG0477	Major facilitator Superfamily
CCL06_RS23690	COG3415	Transposase
CCL06_RS23690	COG2801	Transposase and inactivated derivatives
CCL06_RS23695	COG2982	Protein involved in outer membrane biogenesis
CCL06_RS23700	COG2200	EAL domain
CCL06_RS23710	COG0612	Peptidase, M16
CCL06_RS23715	COG1301	dicarboxylic acid transport
CCL06_RS23720	COG2199	diguanylate cyclase activity
CCL06_RS23720	COG2200	EAL domain
CCL06_RS23725	COG3118	belongs to the thioredoxin family
CCL06_RS23725	COG0457	Tetratricopeptide repeat
CCL06_RS23730	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CCL06_RS23740	COG1215	transferase activity, transferring glycosyl groups
CCL06_RS23765	COG2194	sulfuric ester hydrolase activity
CCL06_RS23770	COG2801	Transposase and inactivated derivatives
CCL06_RS23770	COG3415	Transposase
CCL06_RS23785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCL06_RS23820	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CCL06_RS23830	COG1739	Uncharacterized protein family UPF0029
CCL06_RS23835	COG0006	proline dipeptidase activity
CCL06_RS23845	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCL06_RS23845	COG1024	Enoyl-CoA hydratase
CCL06_RS23850	COG0183	Belongs to the thiolase family
CCL06_RS23860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCL06_RS23870	COG0084	hydrolase, TatD family'
CCL06_RS23875	COG0805	protein transport
CCL06_RS23885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCL06_RS23890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCL06_RS23895	COG3165	ubiquinone biosynthetic process from chorismate
CCL06_RS23900	COG2226	methyltransferase
CCL06_RS23905	COG1322	Protein conserved in bacteria
CCL06_RS23910	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CCL06_RS23915	COG0412	Dienelactone hydrolase
CCL06_RS23920	COG2723	6-phospho-beta-galactosidase activity
CCL06_RS23930	COG0583	DNA-binding transcription factor activity
CCL06_RS23935	COG0697	spore germination
CCL06_RS23940	COG0561	phosphatase activity
CCL06_RS23945	COG2267	carboxylic ester hydrolase activity
CCL06_RS23950	COG1280	lysine exporter protein (LysE YggA)
CCL06_RS23955	COG1280	lysine exporter protein (LysE YggA)
CCL06_RS23990	COG0210	DNA helicase
CCL06_RS23995	COG1011	Hydrolase
CCL06_RS24035	COG0181	hydroxymethylbilane synthase activity
CCL06_RS24045	COG2959	enzyme of heme biosynthesis
CCL06_RS24050	COG3071	HemY protein
CCL06_RS24085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CCL06_RS24100	COG2244	polysaccharide biosynthetic process
CCL06_RS24105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCL06_RS24110	COG0456	acetyltransferase
CCL06_RS24115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CCL06_RS24120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCL06_RS24130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCL06_RS24135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCL06_RS24140	COG3118	belongs to the thioredoxin family
CCL06_RS24150	COG0248	Ppx GppA phosphatase
CCL06_RS24160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCL06_RS24170	COG0583	DNA-binding transcription factor activity
CCL06_RS24175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCL06_RS24185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCL06_RS24190	COG3978	acetolactate synthase activity
CCL06_RS24205	COG0606	chelatase, subunit chli
CCL06_RS24210	COG3085	chromosome segregation
CCL06_RS24265	COG4206	TonB-dependent receptor
CCL06_RS24270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCL06_RS24290	COG0583	DNA-binding transcription factor activity
CCL06_RS24295	COG0165	Argininosuccinate lyase
CCL06_RS24300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCL06_RS24305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCL06_RS24310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCL06_RS24315	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCL06_RS24320	COG2207	Transcriptional regulator
CCL06_RS24330	COG0371	Dehydrogenase
CCL06_RS24335	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CCL06_RS24345	COG0527	aspartate kinase activity
CCL06_RS24345	COG0460	homoserine dehydrogenase
CCL06_RS24350	COG0626	cystathionine gamma-synthase activity
CCL06_RS24365	COG0254	rRNA binding
CCL06_RS24370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCL06_RS24375	COG1609	Transcriptional regulator
CCL06_RS24380	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCL06_RS24395	COG1575	Belongs to the MenA family. Type 1 subfamily
CCL06_RS24405	COG3074	FtsZ-dependent cytokinesis
CCL06_RS24415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCL06_RS24420	COG1494	fructose-1,6-bisphosphatase
CCL06_RS24430	COG3152	Membrane
CCL06_RS24440	COG0149	triose-phosphate isomerase activity
CCL06_RS24450	COG2134	cdp-diacylglycerol pyrophosphatase
CCL06_RS24460	COG0205	6-phosphofructokinase activity
CCL06_RS24470	COG3678	ATP-independent chaperone mediated protein folding
CCL06_RS24475	COG0745	RESPONSE REGULATOR receiver
CCL06_RS24480	COG2205	protein histidine kinase activity
CCL06_RS24485	COG2801	Transposase and inactivated derivatives
CCL06_RS24485	COG3415	Transposase
CCL06_RS24490	COG2258	MOSC domain
CCL06_RS24495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCL06_RS24500	COG2211	Major facilitator Superfamily
CCL06_RS24520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CCL06_RS24535	COG3188	usher protein
CCL06_RS24540	COG3121	Chaperone
CCL06_RS24560	COG0243	molybdopterin cofactor binding
CCL06_RS24560	COG3383	formate dehydrogenase (NAD+) activity
CCL06_RS24565	COG3383	formate dehydrogenase (NAD+) activity
CCL06_RS24565	COG0243	molybdopterin cofactor binding
CCL06_RS24570	COG0437	4 iron, 4 sulfur cluster binding
CCL06_RS24575	COG2864	formate dehydrogenase
CCL06_RS24590	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CCL06_RS24600	COG0456	acetyltransferase
CCL06_RS24615	COG1011	Hydrolase
CCL06_RS24640	COG3852	Histidine kinase
CCL06_RS24655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCL06_RS24665	COG3078	GTPase activator activity
CCL06_RS24685	COG0204	Acyl-transferase
CCL06_RS24695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCL06_RS24700	COG3084	Protein conserved in bacteria
CCL06_RS24705	COG0746	molybdenum cofactor guanylyltransferase activity
CCL06_RS24710	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCL06_RS24735	COG2186	Transcriptional regulator
CCL06_RS24740	COG0477	Major facilitator Superfamily
CCL06_RS24745	COG1609	Transcriptional regulator
CCL06_RS24750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCL06_RS24760	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCL06_RS24765	COG1129	ABC transporter
CCL06_RS24770	COG1869	D-ribose catabolic process
CCL06_RS24775	COG3158	transport of potassium into the cell
CCL06_RS24785	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CCL06_RS24790	COG2502	aspartate--ammonia ligase
CCL06_RS24795	COG1522	sequence-specific DNA binding
CCL06_RS24800	COG0716	FMN binding
CCL06_RS24805	COG0445	tRNA wobble uridine modification
CCL06_RS24810	COG0357	Ribosomal RNA small subunit methyltransferase G
CCL06_RS24815	COG3312	ion transport
CCL06_RS24820	COG0356	it plays a direct role in the translocation of protons across the membrane
CCL06_RS24830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCL06_RS24835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCL06_RS24850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCL06_RS24855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCL06_RS24860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCL06_RS24870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCL06_RS24875	COG0573	inorganic phosphate transmembrane transporter activity
CCL06_RS24880	COG0581	inorganic phosphate transmembrane transporter activity
CCL06_RS24885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCL06_RS24890	COG0704	Plays a role in the regulation of phosphate uptake
CCL06_RS24895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCL06_RS24900	COG2252	PERMEase
CCL06_RS24905	COG0431	NADPH-dependent FMN reductase
CCL06_RS24910	COG2091	lysine biosynthetic process via aminoadipic acid
CCL06_RS24925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CCL06_RS24930	COG0706	membrane insertase activity
