locus-tag	class	description
MS7884_RS00010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MS7884_RS00025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MS7884_RS00030	COG0416	fatty acid biosynthetic process
MS7884_RS00035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MS7884_RS00045	COG0424	maF-like protein
MS7884_RS00050	COG0564	pseudouridine synthase activity
MS7884_RS00060	COG1530	ribonuclease E activity
MS7884_RS00065	COG0583	DNA-binding transcription factor activity
MS7884_RS00070	COG2814	Major facilitator Superfamily
MS7884_RS00080	COG1256	bacterial-type flagellum assembly
MS7884_RS00100	COG4786	Flagellar basal body rod
MS7884_RS00110	COG1749	Flagellar hook protein flgE
MS7884_RS00120	COG1558	bacterial-type flagellum-dependent cell motility
MS7884_RS00155	COG3132	Protein of unknown function, DUF480
MS7884_RS00160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS00165	COG0477	Major facilitator Superfamily
MS7884_RS00175	COG0418	dihydroorotase activity
MS7884_RS00200	COG3038	cytochrome b561
MS7884_RS00205	COG2353	YceI-like domain
MS7884_RS00210	COG1054	Belongs to the UPF0176 family
MS7884_RS00215	COG1560	Kdo2-lipid A biosynthetic process
MS7884_RS00230	COG5645	(Lipo)protein
MS7884_RS00235	COG2943	transferase activity, transferring hexosyl groups
MS7884_RS00255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MS7884_RS00305	COG3381	protein complex oligomerization
MS7884_RS00310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MS7884_RS00315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7884_RS00325	COG0583	DNA-binding transcription factor activity
MS7884_RS00335	COG1335	isochorismatase
MS7884_RS00345	COG1115	amino acid carrier protein
MS7884_RS00350	COG1702	phosphate starvation-inducible protein PhoH
MS7884_RS00360	COG2822	iron ion transport
MS7884_RS00375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS7884_RS00385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS7884_RS00390	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS7884_RS00390	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS7884_RS00390	COG0506	proline dehydrogenase activity
MS7884_RS00400	COG1309	transcriptional regulator
MS7884_RS00405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS00410	COG1335	isochorismatase
MS7884_RS00415	COG0251	oxidation-reduction process
MS7884_RS00420	COG2267	carboxylic ester hydrolase activity
MS7884_RS00425	COG0778	Nitroreductase
MS7884_RS00430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS7884_RS00435	COG2233	PERMEase
MS7884_RS00455	COG3729	General stress protein
MS7884_RS00480	COG1733	regulation of RNA biosynthetic process
MS7884_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS00490	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS00495	COG2239	Acts as a magnesium transporter
MS7884_RS00510	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MS7884_RS00510	COG3264	Mechanosensitive ion channel
MS7884_RS00520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS00525	COG1120	ATPase activity
MS7884_RS00545	COG0670	Belongs to the BI1 family
MS7884_RS00555	COG1254	Belongs to the acylphosphatase family
MS7884_RS00560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MS7884_RS00570	COG1832	CoA-binding protein
MS7884_RS00575	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MS7884_RS00580	COG1803	Methylglyoxal synthase
MS7884_RS00585	COG0210	DNA helicase
MS7884_RS00590	COG3304	Inner membrane component domain
MS7884_RS00595	COG1289	transmembrane transporter activity
MS7884_RS00600	COG3070	regulator of competence-specific genes
MS7884_RS00605	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
MS7884_RS00615	COG3120	sequence-specific DNA binding
MS7884_RS00620	COG1067	ATP-dependent peptidase activity
MS7884_RS00630	COG3130	regulation of translation
MS7884_RS00640	COG3009	Protein conserved in bacteria
MS7884_RS00645	COG3008	intermembrane lipid transfer
MS7884_RS00645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MS7884_RS00650	COG2995	paraquat-inducible protein a
MS7884_RS00655	COG0488	(ABC) transporter
MS7884_RS00660	COG0116	Belongs to the methyltransferase superfamily
MS7884_RS00660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MS7884_RS00665	COG0633	Ferredoxin
MS7884_RS00665	COG3217	Mosc domain protein beta barrel domain protein
MS7884_RS00675	COG0167	dihydroorotate dehydrogenase activity
MS7884_RS00680	COG0431	NADPH-dependent FMN reductase
MS7884_RS00685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS7884_RS00690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS00695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS7884_RS00705	COG0308	aminopeptidase N
MS7884_RS00710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MS7884_RS00715	COG0017	Asparaginyl-tRNA synthetase
MS7884_RS00725	COG1448	Aminotransferase
MS7884_RS00730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7884_RS00735	COG3108	Peptidase M15
MS7884_RS00740	COG2989	Protein conserved in bacteria
MS7884_RS00745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MS7884_RS00750	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MS7884_RS00760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MS7884_RS00770	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MS7884_RS00775	COG3173	Aminoglycoside phosphotransferase
MS7884_RS00780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MS7884_RS00785	COG2835	tetraacyldisaccharide 4'-kinase activity
MS7884_RS00790	COG3214	Protein conserved in bacteria
MS7884_RS00800	COG1132	(ABC) transporter
MS7884_RS00805	COG2333	competence protein COMEC
MS7884_RS00805	COG0658	competence protein
MS7884_RS00810	COG0776	regulation of translation
MS7884_RS00815	COG0539	negative regulation of cytoplasmic translation
MS7884_RS00820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MS7884_RS00825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MS7884_RS00830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MS7884_RS00835	COG2323	membrane
MS7884_RS00840	COG1944	ATP diphosphatase activity
MS7884_RS00845	COG2116	formate transmembrane transporter activity
MS7884_RS00850	COG1882	Formate acetyltransferase
MS7884_RS00855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS7884_RS00865	COG0477	Major facilitator Superfamily
MS7884_RS00875	COG3302	dmso reductase anchor subunit
MS7884_RS00880	COG0437	4 iron, 4 sulfur cluster binding
MS7884_RS00885	COG0243	molybdopterin cofactor binding
MS7884_RS00890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MS7884_RS00895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MS7884_RS00900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MS7884_RS00905	COG1178	ABC-type Fe3 transport system permease component
MS7884_RS00905	COG1674	ftsk spoiiie
MS7884_RS00920	COG0492	ferredoxin-NADP+ reductase activity
MS7884_RS00925	COG4988	ABC transporter
MS7884_RS00930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MS7884_RS00935	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MS7884_RS00940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MS7884_RS00945	COG0542	response to heat
MS7884_RS00950	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MS7884_RS00955	COG1278	Cold shock
MS7884_RS00965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS00970	COG2990	Protein conserved in bacteria
MS7884_RS00975	COG3593	DNA synthesis involved in DNA repair
MS7884_RS00985	COG2431	L-lysine efflux transmembrane transporter activity
MS7884_RS00990	COG1151	hydroxylamine reductase activity
MS7884_RS00995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS7884_RS01000	COG0028	Belongs to the TPP enzyme family
MS7884_RS01005	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MS7884_RS01010	COG0702	epimerase
MS7884_RS01015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS7884_RS01020	COG3397	chitin binding
MS7884_RS01035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MS7884_RS01060	COG2165	general secretion pathway protein
MS7884_RS01070	COG2165	general secretion pathway protein
MS7884_RS01080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MS7884_RS01085	COG1450	Type ii and iii secretion system protein
MS7884_RS01110	COG3023	N-Acetylmuramoyl-L-alanine amidase
MS7884_RS01115	COG0393	Putative heavy-metal-binding
MS7884_RS01125	COG1126	abc transporter atp-binding protein
MS7884_RS01130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS01135	COG4215	(ABC) transporter
MS7884_RS01140	COG4160	amino acid transport
MS7884_RS01150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS01155	COG5002	protein histidine kinase activity
MS7884_RS01160	COG0745	RESPONSE REGULATOR receiver
MS7884_RS01170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MS7884_RS01180	COG1177	transmembrane transport
MS7884_RS01185	COG1176	ABC-type spermidine putrescine transport system, permease component I
MS7884_RS01190	COG3842	ATPase activity
MS7884_RS01195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MS7884_RS01215	COG0778	Nitroreductase
MS7884_RS01240	COG3226	Transcriptional regulator
MS7884_RS01245	COG0738	Major facilitator superfamily
MS7884_RS01250	COG0561	phosphatase activity
MS7884_RS01255	COG2814	Major facilitator Superfamily
MS7884_RS01265	COG0671	phosphoesterase, PA-phosphatase related
MS7884_RS01270	COG1349	DNA-binding transcription factor activity
MS7884_RS01275	COG1686	Belongs to the peptidase S11 family
MS7884_RS01280	COG0625	glutathione transferase activity
MS7884_RS01285	COG2133	pyrroloquinoline quinone binding
MS7884_RS01320	COG1446	asparaginase
MS7884_RS01325	COG0303	'Molybdopterin
MS7884_RS01335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS7884_RS01340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS7884_RS01345	COG1882	Formate acetyltransferase
MS7884_RS01350	COG0561	phosphatase activity
MS7884_RS01360	COG1609	Transcriptional regulator
MS7884_RS01365	COG2271	Major facilitator Superfamily
MS7884_RS01375	COG0488	(ABC) transporter
MS7884_RS01380	COG1376	ErfK ybiS ycfS ynhG family protein
MS7884_RS01385	COG2188	Transcriptional regulator
MS7884_RS01390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS01395	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS01400	COG1538	Outer membrane efflux protein
MS7884_RS01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS01425	COG2382	esterase
MS7884_RS01430	COG2819	hydrolase of the alpha beta superfamily
MS7884_RS01440	COG0667	Aldo Keto reductase
MS7884_RS01450	COG2814	Major facilitator Superfamily
MS7884_RS01455	COG1566	PFAM secretion protein HlyD family protein
MS7884_RS01460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MS7884_RS01465	COG1321	iron dependent repressor
MS7884_RS01475	COG2194	sulfuric ester hydrolase activity
MS7884_RS01480	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MS7884_RS01490	COG0783	Belongs to the Dps family
MS7884_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS01505	COG0765	amino acid transport
MS7884_RS01510	COG1126	abc transporter atp-binding protein
MS7884_RS01515	COG0668	transmembrane transport
MS7884_RS01520	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MS7884_RS01535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS7884_RS01545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS7884_RS01555	COG3121	Chaperone
MS7884_RS01575	COG1199	ATP-dependent helicase activity
MS7884_RS01580	COG0513	Belongs to the DEAD box helicase family
MS7884_RS01585	COG1309	transcriptional regulator
MS7884_RS01590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS01595	COG1131	(ABC) transporter
MS7884_RS01600	COG0842	Transport permease protein
MS7884_RS01605	COG0842	Transport permease protein
MS7884_RS01615	COG3568	Endonuclease Exonuclease Phosphatase
MS7884_RS01620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS7884_RS01625	COG0392	lysyltransferase activity
MS7884_RS01630	COG0670	Belongs to the BI1 family
MS7884_RS01635	COG0314	molybdopterin synthase activity
MS7884_RS01640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MS7884_RS01645	COG0315	cyclic pyranopterin monophosphate synthase activity
MS7884_RS01650	COG0521	Mo-molybdopterin cofactor biosynthetic process
MS7884_RS01685	COG2226	methyltransferase
MS7884_RS01690	COG0156	8-amino-7-oxononanoate synthase activity
MS7884_RS01695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MS7884_RS01700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MS7884_RS01705	COG1881	PFAM PEBP family protein
MS7884_RS01710	COG2986	histidine ammonia-lyase
MS7884_RS01715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MS7884_RS01725	COG0010	Belongs to the arginase family
MS7884_RS01735	COG4677	pectinesterase activity
MS7884_RS01740	COG2706	6-phosphogluconolactonase activity
MS7884_RS01745	COG0561	phosphatase activity
MS7884_RS01755	COG4149	molybdate abc transporter
MS7884_RS01760	COG0725	ABC transporter, periplasmic molybdate-binding protein
MS7884_RS01770	COG2005	Transcriptional regulator
MS7884_RS01770	COG3585	molybdate ion transport
MS7884_RS01775	COG1119	ATPase activity
MS7884_RS01780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MS7884_RS01785	COG1085	galactose-1-phosphate uridylyltransferase
MS7884_RS01790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MS7884_RS01795	COG2017	converts alpha-aldose to the beta-anomer
MS7884_RS01805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS7884_RS01815	COG1230	cation diffusion facilitator family transporter
MS7884_RS01820	COG3201	nicotinamide mononucleotide transporter
MS7884_RS01855	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MS7884_RS01860	COG2885	chlorophyll binding
MS7884_RS01865	COG0823	Involved in the tonB-independent uptake of proteins
MS7884_RS01870	COG3064	Membrane
MS7884_RS01875	COG0848	biopolymer transport protein
MS7884_RS01880	COG0811	peptide transport
MS7884_RS01885	COG0824	Thioesterase
MS7884_RS01890	COG3790	cyd operon protein YbgE
MS7884_RS01895	COG4890	Cyd operon protein YbgT
MS7884_RS01900	COG1294	oxidase, subunit
MS7884_RS01905	COG1271	oxidase subunit
MS7884_RS01910	COG0383	alpha-mannosidase activity
MS7884_RS01915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS01915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS01915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS01920	COG2188	Transcriptional regulator
MS7884_RS01925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS7884_RS01930	COG0045	succinate-CoA ligase (ADP-forming) activity
MS7884_RS01935	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS7884_RS01940	COG0567	Dehydrogenase, E1 component
MS7884_RS01945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS7884_RS01950	COG1053	succinate dehydrogenase
MS7884_RS01955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MS7884_RS01960	COG2009	succinate dehydrogenase
MS7884_RS01970	COG0372	Belongs to the citrate synthase family
MS7884_RS01975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MS7884_RS01985	COG1984	allophanate hydrolase subunit 2
MS7884_RS01990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MS7884_RS01995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MS7884_RS02015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MS7884_RS02020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MS7884_RS02025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MS7884_RS02030	COG2205	protein histidine kinase activity
MS7884_RS02035	COG0745	RESPONSE REGULATOR receiver
MS7884_RS02045	COG1982	Orn Lys Arg decarboxylase major
MS7884_RS02050	COG0531	amino acid
MS7884_RS02055	COG0033	Phosphoglucomutase
MS7884_RS02060	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MS7884_RS02065	COG0596	Alpha beta hydrolase
MS7884_RS02080	COG0735	belongs to the Fur family
MS7884_RS02100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS7884_RS02105	COG1263	PTS System
MS7884_RS02105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS02105	COG2190	(PTS) system
MS7884_RS02115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS7884_RS02120	COG1940	carbohydrate kinase activity
MS7884_RS02120	COG1846	Transcriptional regulator
MS7884_RS02125	COG0647	UMP catabolic process
MS7884_RS02130	COG0367	asparagine synthase
MS7884_RS02175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS7884_RS02180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MS7884_RS02185	COG1702	phosphate starvation-inducible protein PhoH
MS7884_RS02190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MS7884_RS02215	COG0765	amino acid transport
MS7884_RS02220	COG0765	amino acid transport
MS7884_RS02225	COG1126	abc transporter atp-binding protein
MS7884_RS02230	COG1957	nucleoside hydrolase
MS7884_RS02235	COG2888	peptidyl-tyrosine sulfation
MS7884_RS02250	COG1466	dna polymerase III delta subunit
MS7884_RS02260	COG0799	negative regulation of ribosome biogenesis
MS7884_RS02270	COG0768	penicillin binding
MS7884_RS02275	COG0772	Belongs to the SEDS family
MS7884_RS02280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MS7884_RS02285	COG1686	Belongs to the peptidase S11 family
MS7884_RS02295	COG0321	lipoyl(octanoyl) transferase activity
MS7884_RS02300	COG0583	DNA-binding transcription factor activity
MS7884_RS02305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MS7884_RS02310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MS7884_RS02315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS7884_RS02335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS02340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS02360	COG3069	C4-dicarboxylate transmembrane transporter activity
MS7884_RS02365	COG3719	Belongs to the RNase T2 family
MS7884_RS02370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS02375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS02380	COG0006	proline dipeptidase activity
MS7884_RS02385	COG1363	Peptidase, m42
MS7884_RS02390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS02390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS7884_RS02390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS02395	COG2207	Transcriptional regulator
MS7884_RS02405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS7884_RS02410	COG1063	alcohol dehydrogenase
MS7884_RS02430	COG0583	DNA-binding transcription factor activity
MS7884_RS02435	COG3969	phosphoadenosine phosphosulfate
MS7884_RS02440	COG1475	DNA binding
MS7884_RS02445	COG0436	Aminotransferase
MS7884_RS02450	COG0235	Class ii aldolase
MS7884_RS02455	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
MS7884_RS02470	COG3423	Transcriptional regulator
MS7884_RS02480	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MS7884_RS02495	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS02500	COG1129	ABC transporter
MS7884_RS02505	COG0371	Dehydrogenase
MS7884_RS02520	COG2879	small protein
MS7884_RS02525	COG1966	Carbon starvation protein
MS7884_RS02530	COG2050	protein possibly involved in aromatic compounds catabolism
MS7884_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS02540	COG1535	isochorismatase
MS7884_RS02540	COG3433	isochorismatase activity
MS7884_RS02545	COG1021	2,3-dihydroxybenzoate-AMP ligase
MS7884_RS02550	COG1169	isochorismate synthase
MS7884_RS02555	COG4592	Periplasmic binding protein
MS7884_RS02565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS02570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS02575	COG1120	ATPase activity
MS7884_RS02580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MS7884_RS02580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS7884_RS02585	COG3251	PFAM MbtH domain protein
MS7884_RS02590	COG2382	esterase
MS7884_RS02595	COG4771	TonB-dependent receptor
MS7884_RS02600	COG2977	Belongs to the P-Pant transferase superfamily
MS7884_RS02605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7884_RS02610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7884_RS02615	COG1121	(ABC) transporter
MS7884_RS02630	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MS7884_RS02635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS7884_RS02665	COG0601	transmembrane transport
MS7884_RS02670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7884_RS02675	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS02680	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS02715	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MS7884_RS02755	COG4680	protein conserved in bacteria
MS7884_RS02760	COG5499	transcription regulator containing HTH domain
MS7884_RS02770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MS7884_RS02800	COG4774	siderophore transport
MS7884_RS02820	COG2315	Protein conserved in bacteria
MS7884_RS02825	COG0778	Nitroreductase
MS7884_RS02845	COG0477	Major facilitator Superfamily
MS7884_RS02850	COG0668	transmembrane transport
MS7884_RS02855	COG1609	Transcriptional regulator
MS7884_RS02870	COG2211	Major facilitator Superfamily
MS7884_RS02875	COG1113	amino acid transport
MS7884_RS02900	COG2246	polysaccharide biosynthetic process
MS7884_RS02905	COG0463	Glycosyl transferase, family 2
MS7884_RS03035	COG3646	Phage regulatory protein
MS7884_RS03265	COG0582	viral genome integration into host DNA
MS7884_RS03325	COG2501	S4 domain
MS7884_RS03330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS03330	COG1263	PTS System
MS7884_RS03330	COG2190	(PTS) system
MS7884_RS03335	COG1609	Transcriptional regulator
MS7884_RS03340	COG1988	membrane-bound metal-dependent
MS7884_RS03350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MS7884_RS03355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS7884_RS03360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MS7884_RS03365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MS7884_RS03380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MS7884_RS03385	COG4181	ATPase activity
MS7884_RS03390	COG2755	lipolytic protein G-D-S-L family
MS7884_RS03395	COG0300	oxidoreductase activity
MS7884_RS03400	COG3118	belongs to the thioredoxin family
MS7884_RS03405	COG0390	transport system, permease component
MS7884_RS03410	COG4619	ABC transporter
MS7884_RS03420	COG0330	HflC and HflK could
MS7884_RS03425	COG1585	Membrane protein implicated in regulation of membrane protease activity
MS7884_RS03435	COG2217	Heavy metal translocating P-type atpase
MS7884_RS03440	COG3735	TraB family
MS7884_RS03450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS7884_RS03455	COG0737	Belongs to the 5'-nucleotidase family
MS7884_RS03460	COG2223	nitrite transmembrane transporter activity
MS7884_RS03465	COG4651	solute:proton antiporter activity
MS7884_RS03465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS7884_RS03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS03475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MS7884_RS03485	COG0326	Molecular chaperone. Has ATPase activity
MS7884_RS03490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MS7884_RS03495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MS7884_RS03505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MS7884_RS03510	COG2832	Protein of unknown function (DUF454)
MS7884_RS03515	COG3923	Primosomal replication protein n
MS7884_RS03525	COG1196	nuclear chromosome segregation
MS7884_RS03525	COG3264	Mechanosensitive ion channel
MS7884_RS03530	COG1309	transcriptional regulator
MS7884_RS03535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS03540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS03555	COG0110	maltose O-acetyltransferase activity
MS7884_RS03575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MS7884_RS03585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MS7884_RS03605	COG1609	Transcriptional regulator
MS7884_RS03610	COG2364	Membrane
MS7884_RS03615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7884_RS03685	COG0582	viral genome integration into host DNA
MS7884_RS03695	COG3695	enzyme binding
MS7884_RS03700	COG3126	Type III secretion system lipoprotein chaperone (YscW)
MS7884_RS03705	COG1946	Acyl-CoA thioesterase
MS7884_RS03710	COG0004	ammonium transporteR
MS7884_RS03715	COG0347	Belongs to the P(II) protein family
MS7884_RS03720	COG1132	(ABC) transporter
MS7884_RS03725	COG1132	(ABC) transporter
MS7884_RS03730	COG1522	sequence-specific DNA binding
MS7884_RS03740	COG0561	phosphatase activity
MS7884_RS03745	COG4533	DNA binding
MS7884_RS03750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MS7884_RS03760	COG3657	addiction module killer protein
MS7884_RS03765	COG0824	Thioesterase
MS7884_RS03770	COG1555	photosystem II stabilization
MS7884_RS03775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS7884_RS03780	COG0776	regulation of translation
MS7884_RS03785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MS7884_RS03800	COG0544	peptidyl-prolyl cis-trans isomerase activity
MS7884_RS03810	COG0271	Belongs to the BolA IbaG family
MS7884_RS03815	COG3056	Lipoprotein
MS7884_RS03820	COG2223	nitrite transmembrane transporter activity
MS7884_RS03825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MS7884_RS03830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MS7884_RS03835	COG1845	cytochrome c oxidase, subunit III
MS7884_RS03840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MS7884_RS03845	COG0109	protoheme IX farnesyltransferase activity
MS7884_RS03865	COG1129	ABC transporter
MS7884_RS03870	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS03890	COG0235	Class ii aldolase
MS7884_RS03895	COG2814	Major facilitator Superfamily
MS7884_RS03905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MS7884_RS03910	COG0693	protein deglycase activity
MS7884_RS03925	COG0142	geranyltranstransferase activity
MS7884_RS03930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MS7884_RS03935	COG0667	Aldo Keto reductase
MS7884_RS03940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MS7884_RS03945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MS7884_RS03950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MS7884_RS03955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS7884_RS03955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS7884_RS03960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MS7884_RS03965	COG4238	major outer membrane lipoprotein
MS7884_RS03970	COG3248	Nucleoside-binding outer membrane protein
MS7884_RS03985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS7884_RS03990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS7884_RS03995	COG1862	Preprotein translocase
MS7884_RS04010	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
MS7884_RS04015	COG0450	alkyl hydroperoxide reductase
MS7884_RS04030	COG0366	Alpha amylase catalytic
MS7884_RS04050	COG5002	protein histidine kinase activity
MS7884_RS04060	COG0420	3'-5' exonuclease activity
MS7884_RS04065	COG0419	ATPase involved in DNA repair
MS7884_RS04070	COG1940	carbohydrate kinase activity
MS7884_RS04080	COG3123	guanosine phosphorylase activity
MS7884_RS04085	COG4126	flavin adenine dinucleotide binding
MS7884_RS04095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MS7884_RS04100	COG1671	Belongs to the UPF0178 family
MS7884_RS04105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MS7884_RS04110	COG3706	GGDEF domain
MS7884_RS04135	COG1181	Belongs to the D-alanine--D-alanine ligase family
MS7884_RS04155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MS7884_RS04160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MS7884_RS04180	COG0113	porphobilinogen synthase activity
MS7884_RS04190	COG2175	clavaminate synthase activity
MS7884_RS04195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS7884_RS04200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MS7884_RS04205	COG4521	taurine ABC transporter
MS7884_RS04220	COG2271	Major facilitator Superfamily
MS7884_RS04225	COG1840	ABC-type Fe3 transport system, periplasmic component
MS7884_RS04235	COG3842	ATPase activity
MS7884_RS04250	COG3710	Transcriptional regulator
MS7884_RS04255	COG2200	EAL domain
MS7884_RS04255	COG2771	luxR family
MS7884_RS04275	COG3121	Chaperone
MS7884_RS04280	COG3188	usher protein
MS7884_RS04295	COG2040	homocysteine
MS7884_RS04300	COG0833	amino acid
MS7884_RS04305	COG0628	permease
MS7884_RS04320	COG5001	Diguanylate cyclase
MS7884_RS04320	COG3300	MHYT domain
MS7884_RS04335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MS7884_RS04345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MS7884_RS04350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MS7884_RS04355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS7884_RS04365	COG1073	alpha beta
MS7884_RS04375	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS7884_RS04380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MS7884_RS04385	COG2991	Protein conserved in bacteria
MS7884_RS04400	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MS7884_RS04405	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MS7884_RS04420	COG3034	peptidoglycan biosynthetic process
MS7884_RS04425	COG0121	glutamine amidotransferase
MS7884_RS04440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS7884_RS04450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7884_RS04460	COG0747	negative chemotaxis
MS7884_RS04465	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS04470	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS04495	COG2226	methyltransferase
MS7884_RS04500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7884_RS04505	COG0741	lytic transglycosylase activity
MS7884_RS04505	COG1388	LysM domain
MS7884_RS04510	COG2226	methyltransferase
MS7884_RS04515	COG3021	interspecies interaction between organisms
MS7884_RS04520	COG2814	Major facilitator Superfamily
MS7884_RS04525	COG0583	DNA-binding transcription factor activity
MS7884_RS04565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MS7884_RS04575	COG2011	ABC-type metal ion transport system permease component
MS7884_RS04580	COG1464	Belongs to the NlpA lipoprotein family
MS7884_RS04590	COG1720	tRNA m6t6A37 methyltransferase activity
MS7884_RS04600	COG3015	lipoprotein NlpE involved in copper resistance
MS7884_RS04605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MS7884_RS04620	COG4568	rho-dependent transcription termination
MS7884_RS04625	COG0037	tRNA processing
MS7884_RS04630	COG0346	lactoylglutathione lyase activity
MS7884_RS04635	COG1982	Orn Lys Arg decarboxylase major
MS7884_RS04640	COG0825	malonyl-CoA metabolic process
MS7884_RS04650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MS7884_RS04655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS7884_RS04660	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS7884_RS04665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MS7884_RS04680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS7884_RS04685	COG0750	zinc metalloprotease
MS7884_RS04690	COG0575	Belongs to the CDS family
MS7884_RS04700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MS7884_RS04745	COG3835	regulator
MS7884_RS04750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS7884_RS04755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MS7884_RS04760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MS7884_RS04770	COG2860	membrane
MS7884_RS04775	COG0316	Belongs to the HesB IscA family
MS7884_RS04785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MS7884_RS04795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS04800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS7884_RS04805	COG1120	ATPase activity
MS7884_RS04810	COG4774	siderophore transport
MS7884_RS04820	COG3188	usher protein
MS7884_RS04825	COG3121	Chaperone
MS7884_RS04835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MS7884_RS04840	COG1643	Atp-dependent helicase
MS7884_RS04845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MS7884_RS04850	COG1489	DNA binding
MS7884_RS04860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS7884_RS04865	COG0617	tRNA 3'-terminal CCA addition
MS7884_RS04870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MS7884_RS04880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MS7884_RS04885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MS7884_RS04895	COG3121	Chaperone
MS7884_RS04900	COG3188	usher protein
MS7884_RS04910	COG3539	Fimbrial protein
MS7884_RS04925	COG0726	polysaccharide deacetylase
MS7884_RS04930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS04935	COG0842	Transport permease protein
MS7884_RS04940	COG1131	(ABC) transporter
MS7884_RS04945	COG0288	reversible hydration of carbon dioxide
MS7884_RS04955	COG4993	Dehydrogenase
MS7884_RS04970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MS7884_RS04990	COG3064	Membrane
MS7884_RS05000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS7884_RS05005	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS7884_RS05010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MS7884_RS05015	COG2186	Transcriptional regulator
MS7884_RS05020	COG1113	amino acid transport
MS7884_RS05025	COG2211	Major facilitator Superfamily
MS7884_RS05030	COG3940	Belongs to the glycosyl hydrolase 43 family
MS7884_RS05035	COG3725	Membrane protein required for beta-lactamase induction
MS7884_RS05040	COG3023	N-Acetylmuramoyl-L-alanine amidase
MS7884_RS05050	COG4969	Belongs to the N-Me-Phe pilin family
MS7884_RS05055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MS7884_RS05060	COG1459	type II secretion system
MS7884_RS05065	COG0516	GMP reductase activity
MS7884_RS05075	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MS7884_RS05080	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MS7884_RS05085	COG0494	nUDIX hydrolase
MS7884_RS05090	COG0653	protein targeting
MS7884_RS05100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MS7884_RS05105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MS7884_RS05110	COG0849	cell division
MS7884_RS05120	COG1181	Belongs to the D-alanine--D-alanine ligase family
MS7884_RS05135	COG0772	Belongs to the SEDS family
MS7884_RS05145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS7884_RS05150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MS7884_RS05155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MS7884_RS05160	COG0768	penicillin binding
MS7884_RS05175	COG2001	Belongs to the MraZ family
MS7884_RS05180	COG1609	Transcriptional regulator
MS7884_RS05190	COG0028	Belongs to the TPP enzyme family
MS7884_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MS7884_RS05225	COG2814	Major facilitator Superfamily
MS7884_RS05245	COG1178	ABC-type Fe3 transport system permease component
MS7884_RS05255	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS05265	COG1069	ribulokinase activity
MS7884_RS05270	COG2160	L-arabinose isomerase activity
MS7884_RS05275	COG0235	Class ii aldolase
MS7884_RS05280	COG0417	DNA replication proofreading
MS7884_RS05285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MS7884_RS05290	COG0564	pseudouridine synthase activity
MS7884_RS05295	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MS7884_RS05300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS7884_RS05305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS7884_RS05310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MS7884_RS05320	COG2967	ApaG domain
MS7884_RS05325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MS7884_RS05340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS7884_RS05340	COG0475	glutathione-regulated potassium exporter activity
MS7884_RS05370	COG0505	Belongs to the CarA family
MS7884_RS05380	COG1609	Transcriptional regulator
MS7884_RS05395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS05400	COG3715	PTS system
MS7884_RS05405	COG3716	PTS system mannose fructose sorbose family IID component
MS7884_RS05425	COG1047	Peptidyl-prolyl cis-trans
MS7884_RS05440	COG0196	riboflavin kinase activity
MS7884_RS05450	COG0268	Binds directly to 16S ribosomal RNA
MS7884_RS05455	COG0583	DNA-binding transcription factor activity
MS7884_RS05460	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MS7884_RS05470	COG0443	Heat shock 70 kDa protein
MS7884_RS05475	COG1584	GPR1 FUN34 yaaH family protein
MS7884_RS05480	COG0477	Major facilitator Superfamily
MS7884_RS05485	COG0521	Mo-molybdopterin cofactor biosynthetic process
MS7884_RS05495	COG1115	amino acid carrier protein
MS7884_RS05510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MS7884_RS05520	COG0527	aspartate kinase activity
MS7884_RS05520	COG0460	homoserine dehydrogenase
MS7884_RS05530	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MS7884_RS05540	COG0745	RESPONSE REGULATOR receiver
MS7884_RS05545	COG3045	CreA protein
MS7884_RS05550	COG3708	Transcriptional regulator
MS7884_RS05550	COG2207	Transcriptional regulator
MS7884_RS05555	COG0406	alpha-ribazole phosphatase activity
MS7884_RS05560	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MS7884_RS05565	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
MS7884_RS05570	COG0741	lytic transglycosylase activity
MS7884_RS05580	COG0488	(ABC) transporter
MS7884_RS05605	COG0560	Phosphoserine phosphatase
MS7884_RS05610	COG3726	membrane protein affecting hemolysin expression
MS7884_RS05630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MS7884_RS05640	COG1328	CTP reductase activity
MS7884_RS05645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MS7884_RS05650	COG0084	hydrolase, TatD family'
MS7884_RS05655	COG4667	esterase of the alpha-beta hydrolase superfamily
MS7884_RS05660	COG5487	UPF0391 membrane protein
MS7884_RS05665	COG2823	Periplasmic or secreted lipoprotein
MS7884_RS05670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MS7884_RS05675	COG1011	Hydrolase
MS7884_RS05680	COG0456	acetyltransferase
MS7884_RS05685	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
MS7884_RS05690	COG2813	Specifically methylates the guanine in position
MS7884_RS05720	COG4114	ferric iron reductase
MS7884_RS05725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS05725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS05730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS7884_RS05735	COG2197	response regulator
MS7884_RS05740	COG2197	response regulator
MS7884_RS05745	COG2966	Psort location CytoplasmicMembrane, score
MS7884_RS05750	COG3610	response to peptide
MS7884_RS05755	COG1846	Transcriptional regulator
MS7884_RS05760	COG1764	response to oxidative stress
MS7884_RS05770	COG1484	DNA-dependent DNA replication
MS7884_RS05790	COG0840	transmembrane signaling receptor activity
MS7884_RS05795	COG1846	Transcriptional regulator
MS7884_RS05800	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS7884_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS05810	COG3384	dioxygenase
MS7884_RS05820	COG3971	2-oxopent-4-enoate hydratase activity
MS7884_RS05840	COG2368	4-hydroxyphenylacetate
MS7884_RS05845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS7884_RS05850	COG1349	DNA-binding transcription factor activity
MS7884_RS05855	COG1966	Carbon starvation protein
MS7884_RS05860	COG2879	small protein
MS7884_RS05865	COG0523	cobalamin synthesis protein
MS7884_RS05880	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS05905	COG2733	membrane
MS7884_RS05915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS05925	COG0640	Transcriptional regulator
MS7884_RS05935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS7884_RS05945	COG5457	Domain of unknown function (DUF1127)
MS7884_RS05950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7884_RS05975	COG2850	peptidyl-arginine hydroxylation
MS7884_RS05980	COG0583	DNA-binding transcription factor activity
MS7884_RS05990	COG0309	Hydrogenase expression formation protein (HypE)
MS7884_RS05995	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MS7884_RS06025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS7884_RS06025	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MS7884_RS06095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MS7884_RS06100	COG1414	Transcriptional regulator
MS7884_RS06105	COG3507	Belongs to the glycosyl hydrolase 43 family
MS7884_RS06110	COG2211	Major facilitator Superfamily
MS7884_RS06115	COG0129	dihydroxy-acid dehydratase activity
MS7884_RS06120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS7884_RS06125	COG2731	YhcH YjgK YiaL family protein
MS7884_RS06130	COG2235	arginine
MS7884_RS06145	COG1288	antiporter activity
MS7884_RS06150	COG1438	arginine binding
MS7884_RS06160	COG0540	Belongs to the ATCase OTCase family
MS7884_RS06170	COG0251	oxidation-reduction process
MS7884_RS06175	COG3397	chitin binding
MS7884_RS06180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MS7884_RS06195	COG1609	Transcriptional regulator
MS7884_RS06200	COG1263	PTS System
MS7884_RS06200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS06205	COG0366	Alpha amylase catalytic
MS7884_RS06225	COG0383	alpha-mannosidase activity
MS7884_RS06230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS06230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS06230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS06240	COG0602	queuosine metabolic process
MS7884_RS06245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS06245	COG3711	transcriptional antiterminator
MS7884_RS06265	COG3964	amidohydrolase
MS7884_RS06305	COG0312	modulator of DNA gyrase
MS7884_RS06310	COG3028	Belongs to the UPF0307 family
MS7884_RS06315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MS7884_RS06330	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS06335	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS06340	COG1129	ABC transporter
MS7884_RS06345	COG1879	ABC-type sugar transport system periplasmic component
MS7884_RS06355	COG2105	PFAM AIG2 family protein
MS7884_RS06360	COG2911	Protein conserved in bacteria
MS7884_RS06365	COG0729	surface antigen
MS7884_RS06370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MS7884_RS06375	COG1253	flavin adenine dinucleotide binding
MS7884_RS06400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MS7884_RS06405	COG1218	3'(2'),5'-bisphosphate nucleotidase
MS7884_RS06415	COG1733	regulation of RNA biosynthetic process
MS7884_RS06420	COG0702	epimerase
MS7884_RS06430	COG0697	spore germination
MS7884_RS06435	COG0840	transmembrane signaling receptor activity
MS7884_RS06445	COG1113	amino acid transport
MS7884_RS06450	COG0545	Peptidyl-prolyl cis-trans isomerase
MS7884_RS06455	COG3061	Opacity-associated protein A
MS7884_RS06460	COG0697	spore germination
MS7884_RS06465	COG0359	binds to the 23S rRNA
MS7884_RS06470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MS7884_RS06475	COG2965	DNA replication, synthesis of RNA primer
MS7884_RS06515	COG3037	sugar-specific permease SgaT UlaA
MS7884_RS06530	COG1073	alpha beta
MS7884_RS06535	COG3650	response to hydrogen peroxide
MS7884_RS06550	COG1960	acyl-CoA dehydrogenase activity
MS7884_RS06555	COG0477	Major facilitator Superfamily
MS7884_RS06560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS7884_RS06565	COG0557	exoribonuclease II activity
MS7884_RS06570	COG1959	2 iron, 2 sulfur cluster binding
MS7884_RS06580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MS7884_RS06585	COG0330	HflC and HflK could
MS7884_RS06590	COG0330	HflC and HflK could
MS7884_RS06595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MS7884_RS06600	COG1923	regulation of RNA biosynthetic process
MS7884_RS06605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MS7884_RS06610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MS7884_RS06620	COG0802	atpase or kinase
MS7884_RS06625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MS7884_RS06625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MS7884_RS06630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MS7884_RS06665	COG1511	domain protein
MS7884_RS06665	COG3264	Mechanosensitive ion channel
MS7884_RS06675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MS7884_RS06680	COG1053	succinate dehydrogenase
MS7884_RS06685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS7884_RS06690	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
MS7884_RS06700	COG0583	DNA-binding transcription factor activity
MS7884_RS06725	COG5510	response to toxic substance
MS7884_RS06750	COG3366	ferrous iron transmembrane transporter activity
MS7884_RS06755	COG0700	Nucleoside recognition
MS7884_RS06760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS7884_RS06765	COG0459	protein refolding
MS7884_RS06775	COG0531	amino acid
MS7884_RS06780	COG3030	protein affecting phage T7 exclusion by the F plasmid
MS7884_RS06785	COG1027	Aspartate ammonia-lyase
MS7884_RS06790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS7884_RS06805	COG1309	transcriptional regulator
MS7884_RS06855	COG4974	Belongs to the 'phage' integrase family
MS7884_RS06890	COG4735	regulation of single-species biofilm formation
MS7884_RS06895	COG2378	regulation of single-species biofilm formation
MS7884_RS06935	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MS7884_RS06940	COG1301	dicarboxylic acid transport
MS7884_RS06950	COG3162	membrane
MS7884_RS06955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS7884_RS06960	COG1346	cytolysis
MS7884_RS06970	COG0583	DNA-binding transcription factor activity
MS7884_RS06975	COG0025	NhaP-type Na H and K H
MS7884_RS06985	COG2252	PERMEase
MS7884_RS06995	COG0625	glutathione transferase activity
MS7884_RS07000	COG0789	Transcriptional regulator
MS7884_RS07010	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MS7884_RS07015	COG2199	diguanylate cyclase activity
MS7884_RS07025	COG0629	single-stranded DNA binding
MS7884_RS07035	COG2315	Protein conserved in bacteria
MS7884_RS07045	COG3700	Belongs to the class B bacterial acid phosphatase family
MS7884_RS07050	COG1448	Aminotransferase
MS7884_RS07060	COG0305	Participates in initiation and elongation during chromosome replication
MS7884_RS07065	COG0604	alcohol dehydrogenase
MS7884_RS07075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS7884_RS07090	COG0735	belongs to the Fur family
MS7884_RS07095	COG3237	CsbD-like
MS7884_RS07100	COG0534	Mate efflux family protein
MS7884_RS07105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MS7884_RS07110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MS7884_RS07115	COG2937	Belongs to the GPAT DAPAT family
MS7884_RS07125	COG3161	chorismate lyase activity
MS7884_RS07135	COG4580	involved in the transport of maltose and maltodextrins
MS7884_RS07160	COG3223	Belongs to the PsiE family
MS7884_RS07165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS7884_RS07190	COG0527	aspartate kinase activity
MS7884_RS07205	COG1187	pseudouridine synthase activity
MS7884_RS07235	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MS7884_RS07245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MS7884_RS07280	COG0151	Belongs to the GarS family
MS7884_RS07295	COG3068	Protein conserved in bacteria
MS7884_RS07300	COG1515	deoxyribonuclease V activity
MS7884_RS07305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MS7884_RS07315	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MS7884_RS07330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MS7884_RS07335	COG2104	thiamine diphosphate biosynthetic process
MS7884_RS07340	COG2022	thiamine diphosphate biosynthetic process
MS7884_RS07350	COG3706	GGDEF domain
MS7884_RS07400	COG0250	Participates in transcription elongation, termination and antitermination
MS7884_RS07435	COG1072	(Pantothenic acid kinase))
MS7884_RS07440	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS07445	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS07450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7884_RS07455	COG0601	transmembrane transport
MS7884_RS07460	COG0747	negative chemotaxis
MS7884_RS07475	COG2223	nitrite transmembrane transporter activity
MS7884_RS07480	COG5571	outer membrane autotransporter
MS7884_RS07485	COG2818	Glycosylase
MS7884_RS07490	COG0456	acetyltransferase
MS7884_RS07495	COG0243	molybdopterin cofactor binding
MS7884_RS07500	COG2885	chlorophyll binding
MS7884_RS07505	COG1609	Transcriptional regulator
MS7884_RS07515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS07525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MS7884_RS07530	COG1278	Cold shock
MS7884_RS07540	COG2944	sequence-specific DNA binding
MS7884_RS07545	COG0488	(ABC) transporter
MS7884_RS07555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MS7884_RS07565	COG0084	hydrolase, TatD family'
MS7884_RS07570	COG0805	protein transport
MS7884_RS07585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MS7884_RS07590	COG3165	ubiquinone biosynthetic process from chorismate
MS7884_RS07595	COG2226	methyltransferase
MS7884_RS07600	COG1322	Protein conserved in bacteria
MS7884_RS07610	COG0412	Dienelactone hydrolase
MS7884_RS07620	COG0583	DNA-binding transcription factor activity
MS7884_RS07625	COG0697	spore germination
MS7884_RS07630	COG0561	phosphatase activity
MS7884_RS07635	COG2267	carboxylic ester hydrolase activity
MS7884_RS07640	COG1280	lysine exporter protein (LysE YggA)
MS7884_RS07645	COG1280	lysine exporter protein (LysE YggA)
MS7884_RS07655	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
MS7884_RS07680	COG0210	DNA helicase
MS7884_RS07685	COG1011	Hydrolase
MS7884_RS07705	COG5567	small periplasmic lipoprotein
MS7884_RS07725	COG0181	hydroxymethylbilane synthase activity
MS7884_RS07735	COG2959	enzyme of heme biosynthesis
MS7884_RS07740	COG3071	HemY protein
MS7884_RS07770	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MS7884_RS07785	COG2244	polysaccharide biosynthetic process
MS7884_RS07790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MS7884_RS07795	COG0456	acetyltransferase
MS7884_RS07800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MS7884_RS07805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS7884_RS07815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS7884_RS07820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MS7884_RS07825	COG3118	belongs to the thioredoxin family
MS7884_RS07835	COG0248	Ppx GppA phosphatase
MS7884_RS07845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS7884_RS07855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MS7884_RS07860	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MS7884_RS07865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MS7884_RS07870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS7884_RS07875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MS7884_RS07880	COG4942	peptidase
MS7884_RS07885	COG2861	carbohydrate metabolic process
MS7884_RS07890	COG0463	Glycosyl transferase, family 2
MS7884_RS07895	COG0438	transferase activity, transferring glycosyl groups
MS7884_RS07905	COG1063	alcohol dehydrogenase
MS7884_RS07920	COG0859	PFAM glycosyl transferase family 9
MS7884_RS07925	COG0859	PFAM glycosyl transferase family 9
MS7884_RS07950	COG0859	PFAM glycosyl transferase family 9
MS7884_RS07960	COG0438	transferase activity, transferring glycosyl groups
MS7884_RS07965	COG1216	Glycosyl transferase, family 2
MS7884_RS07970	COG1519	Transferase
MS7884_RS07980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MS7884_RS07985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MS7884_RS07990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MS7884_RS07995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MS7884_RS08000	COG2003	Belongs to the UPF0758 family
MS7884_RS08005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MS7884_RS08010	COG0756	dUTP diphosphatase activity
MS7884_RS08020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MS7884_RS08035	COG1561	YicC-like family, N-terminal region
MS7884_RS08060	COG3561	AntA/AntB antirepressor
MS7884_RS08125	COG2860	membrane
MS7884_RS08130	COG0489	protein tyrosine kinase activity
MS7884_RS08130	COG3206	protein involved in exopolysaccharide biosynthesis
MS7884_RS08135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MS7884_RS08140	COG1596	polysaccharide export
MS7884_RS08145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS7884_RS08165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MS7884_RS08180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS7884_RS08185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS7884_RS08190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MS7884_RS08195	COG0786	glutamate:sodium symporter activity
MS7884_RS08200	COG2233	PERMEase
MS7884_RS08205	COG2982	Protein involved in outer membrane biogenesis
MS7884_RS08210	COG1501	Belongs to the glycosyl hydrolase 31 family
MS7884_RS08215	COG2211	Major facilitator Superfamily
MS7884_RS08260	COG0519	Catalyzes the synthesis of GMP from XMP
MS7884_RS08290	COG3121	Chaperone
MS7884_RS08320	COG2351	hydroxyisourate hydrolase activity
MS7884_RS08325	COG3272	Protein of unknown function (DUF1722)
MS7884_RS08350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MS7884_RS08365	COG2274	protein secretion by the type I secretion system
MS7884_RS08390	COG3188	usher protein
MS7884_RS08420	COG3121	Chaperone
MS7884_RS08425	COG3188	usher protein
MS7884_RS08450	COG1464	Belongs to the NlpA lipoprotein family
MS7884_RS08460	COG1309	transcriptional regulator
MS7884_RS08465	COG0454	-acetyltransferase
MS7884_RS08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS08480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS08490	COG2814	Major facilitator Superfamily
MS7884_RS08500	COG1609	Transcriptional regulator
MS7884_RS08510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS08510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS08515	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS08520	COG1447	Phosphotransferase system cellobiose-specific component IIA
MS7884_RS08525	COG4580	involved in the transport of maltose and maltodextrins
MS7884_RS08530	COG0697	spore germination
MS7884_RS08550	COG0583	DNA-binding transcription factor activity
MS7884_RS08555	COG0596	Alpha beta hydrolase
MS7884_RS08575	COG2197	response regulator
MS7884_RS08580	COG0440	acetolactate synthase activity
MS7884_RS08585	COG0028	Belongs to the TPP enzyme family
MS7884_RS08625	COG2814	Major facilitator Superfamily
MS7884_RS08635	COG0583	DNA-binding transcription factor activity
MS7884_RS08640	COG2610	gluconate transmembrane transporter activity
MS7884_RS08650	COG0641	radical SAM
MS7884_RS08660	COG2149	membrane
MS7884_RS08665	COG3119	arylsulfatase activity
MS7884_RS08670	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS7884_RS08675	COG2207	Transcriptional regulator
MS7884_RS08690	COG2188	Transcriptional regulator
MS7884_RS08715	COG2985	domain, Protein
MS7884_RS08720	COG0071	Belongs to the small heat shock protein (HSP20) family
MS7884_RS08730	COG5645	(Lipo)protein
MS7884_RS08735	COG0823	Involved in the tonB-independent uptake of proteins
MS7884_RS08740	COG2271	Major facilitator Superfamily
MS7884_RS08745	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS08750	COG0800	Aldolase
MS7884_RS08755	COG3734	2-keto-3-deoxy-galactonokinase
MS7884_RS08760	COG2186	Transcriptional regulator
MS7884_RS08765	COG0561	phosphatase activity
MS7884_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS08770	COG0604	alcohol dehydrogenase
MS7884_RS08770	COG3321	synthase
MS7884_RS08775	COG0583	DNA-binding transcription factor activity
MS7884_RS08785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MS7884_RS08790	COG0592	DNA-directed DNA polymerase activity
MS7884_RS08820	COG0706	membrane insertase activity
MS7884_RS08840	COG2091	lysine biosynthetic process via aminoadipic acid
MS7884_RS08845	COG0431	NADPH-dependent FMN reductase
MS7884_RS08850	COG2252	PERMEase
MS7884_RS08855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS08860	COG0704	Plays a role in the regulation of phosphate uptake
MS7884_RS08865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MS7884_RS08870	COG0581	inorganic phosphate transmembrane transporter activity
MS7884_RS08875	COG0573	inorganic phosphate transmembrane transporter activity
MS7884_RS08880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MS7884_RS08885	COG3539	Fimbrial protein
MS7884_RS08895	COG3121	Chaperone
MS7884_RS08900	COG3539	Fimbrial protein
MS7884_RS08910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MS7884_RS08915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MS7884_RS08920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MS7884_RS08935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MS7884_RS08940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MS7884_RS08950	COG0356	it plays a direct role in the translocation of protons across the membrane
MS7884_RS08955	COG3312	ion transport
MS7884_RS08960	COG0357	Ribosomal RNA small subunit methyltransferase G
MS7884_RS08965	COG0445	tRNA wobble uridine modification
MS7884_RS08970	COG0716	FMN binding
MS7884_RS08975	COG1522	sequence-specific DNA binding
MS7884_RS08980	COG2502	aspartate--ammonia ligase
MS7884_RS08985	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MS7884_RS08995	COG3158	transport of potassium into the cell
MS7884_RS09000	COG1869	D-ribose catabolic process
MS7884_RS09005	COG1129	ABC transporter
MS7884_RS09010	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS09020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS09025	COG1609	Transcriptional regulator
MS7884_RS09030	COG0477	Major facilitator Superfamily
MS7884_RS09035	COG2186	Transcriptional regulator
MS7884_RS09060	COG1763	Mo-molybdopterin cofactor biosynthetic process
MS7884_RS09065	COG0746	molybdenum cofactor guanylyltransferase activity
MS7884_RS09070	COG3084	Protein conserved in bacteria
MS7884_RS09075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MS7884_RS09085	COG0204	Acyl-transferase
MS7884_RS09105	COG3078	GTPase activator activity
MS7884_RS09115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS7884_RS09130	COG3852	Histidine kinase
MS7884_RS09150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS7884_RS09170	COG1501	Belongs to the glycosyl hydrolase 31 family
MS7884_RS09180	COG3684	Belongs to the aldolase LacD family
MS7884_RS09190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS09195	COG1349	DNA-binding transcription factor activity
MS7884_RS09200	COG1011	Hydrolase
MS7884_RS09215	COG0456	acetyltransferase
MS7884_RS09225	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS7884_RS09235	COG3058	Necessary for formate dehydrogenase activity
MS7884_RS09240	COG2864	formate dehydrogenase
MS7884_RS09245	COG0437	4 iron, 4 sulfur cluster binding
MS7884_RS09270	COG3121	Chaperone
MS7884_RS09275	COG3188	usher protein
MS7884_RS09290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MS7884_RS09310	COG2211	Major facilitator Superfamily
MS7884_RS09320	COG1454	alcohol dehydrogenase
MS7884_RS09330	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS09335	COG1129	ABC transporter
MS7884_RS09345	COG0235	Class ii aldolase
MS7884_RS09350	COG4806	L-rhamnose isomerase
MS7884_RS09355	COG1070	Carbohydrate kinase
MS7884_RS09360	COG4977	sequence-specific DNA binding
MS7884_RS09365	COG4977	sequence-specific DNA binding
MS7884_RS09365	COG1917	Cupin 2, conserved barrel domain protein
MS7884_RS09375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MS7884_RS09380	COG2258	MOSC domain
MS7884_RS09385	COG2205	protein histidine kinase activity
MS7884_RS09390	COG0745	RESPONSE REGULATOR receiver
MS7884_RS09395	COG3678	ATP-independent chaperone mediated protein folding
MS7884_RS09410	COG0205	6-phosphofructokinase activity
MS7884_RS09420	COG2134	cdp-diacylglycerol pyrophosphatase
MS7884_RS09430	COG0149	triose-phosphate isomerase activity
MS7884_RS09440	COG3152	Membrane
MS7884_RS09450	COG1494	fructose-1,6-bisphosphatase
MS7884_RS09460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MS7884_RS09465	COG3074	FtsZ-dependent cytokinesis
MS7884_RS09480	COG1575	Belongs to the MenA family. Type 1 subfamily
MS7884_RS09495	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MS7884_RS09500	COG1609	Transcriptional regulator
MS7884_RS09505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MS7884_RS09510	COG0254	rRNA binding
MS7884_RS09520	COG0626	cystathionine gamma-synthase activity
MS7884_RS09525	COG0460	homoserine dehydrogenase
MS7884_RS09525	COG0527	aspartate kinase activity
MS7884_RS09535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MS7884_RS09540	COG0371	Dehydrogenase
MS7884_RS09550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MS7884_RS09555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MS7884_RS09560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MS7884_RS09570	COG0165	Argininosuccinate lyase
MS7884_RS09575	COG0583	DNA-binding transcription factor activity
MS7884_RS09595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MS7884_RS09600	COG4206	TonB-dependent receptor
MS7884_RS09655	COG3085	chromosome segregation
MS7884_RS09675	COG3978	acetolactate synthase activity
MS7884_RS09680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MS7884_RS09690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS7884_RS09695	COG0583	DNA-binding transcription factor activity
MS7884_RS09705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MS7884_RS09710	COG2271	Major facilitator Superfamily
MS7884_RS09715	COG1304	FMN binding
MS7884_RS09720	COG2186	Transcriptional regulator
MS7884_RS09730	COG3539	Fimbrial protein
MS7884_RS09735	COG3121	Chaperone
MS7884_RS09755	COG3722	fumarate hydratase activity
MS7884_RS09765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS09765	COG2213	PTS system mannitol-specific
MS7884_RS09775	COG1566	PFAM secretion protein HlyD family protein
MS7884_RS09780	COG0625	glutathione transferase activity
MS7884_RS09790	COG3276	selenocysteine insertion sequence binding
MS7884_RS09795	COG1940	carbohydrate kinase activity
MS7884_RS09800	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS09820	COG2211	Major facilitator Superfamily
MS7884_RS09830	COG0235	Class ii aldolase
MS7884_RS09835	COG3623	hexulose-6-phosphate isomerase
MS7884_RS09840	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MS7884_RS09845	COG1070	Carbohydrate kinase
MS7884_RS09850	COG2271	Major facilitator Superfamily
MS7884_RS09860	COG2731	YhcH YjgK YiaL family protein
MS7884_RS09870	COG1414	Transcriptional regulator
MS7884_RS09875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS7884_RS09880	COG3977	Valine--pyruvate aminotransferase
MS7884_RS09885	COG0366	Alpha amylase catalytic
MS7884_RS09895	COG2992	FlgJ-related protein
MS7884_RS09900	COG1609	Transcriptional regulator
MS7884_RS09900	COG2207	Transcriptional regulator
MS7884_RS09905	COG4214	carbohydrate transport
MS7884_RS09915	COG4213	ABC transporter substrate-binding protein
MS7884_RS09925	COG2115	Belongs to the xylose isomerase family
MS7884_RS09930	COG1070	Carbohydrate kinase
MS7884_RS09935	COG3274	enterobacterial common antigen metabolic process
MS7884_RS09945	COG0752	glycyl-tRNA synthetase alpha subunit
MS7884_RS09950	COG0751	glycine-tRNA ligase activity
MS7884_RS09955	COG0183	Belongs to the thiolase family
MS7884_RS09960	COG1024	Enoyl-CoA hydratase
MS7884_RS09960	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS7884_RS09970	COG0006	proline dipeptidase activity
MS7884_RS09975	COG1739	Uncharacterized protein family UPF0029
MS7884_RS09985	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MS7884_RS10020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MS7884_RS10030	COG2194	sulfuric ester hydrolase activity
MS7884_RS10060	COG1215	transferase activity, transferring glycosyl groups
MS7884_RS10065	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MS7884_RS10070	COG0457	Tetratricopeptide repeat
MS7884_RS10070	COG3118	belongs to the thioredoxin family
MS7884_RS10075	COG2199	diguanylate cyclase activity
MS7884_RS10075	COG2200	EAL domain
MS7884_RS10080	COG1301	dicarboxylic acid transport
MS7884_RS10085	COG0612	Peptidase, M16
MS7884_RS10095	COG2200	EAL domain
MS7884_RS10100	COG2982	Protein involved in outer membrane biogenesis
MS7884_RS10105	COG0477	Major facilitator Superfamily
MS7884_RS10110	COG1295	ribonuclease BN
MS7884_RS10115	COG0583	DNA-binding transcription factor activity
MS7884_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS10125	COG2197	response regulator
MS7884_RS10135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS10155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS7884_RS10160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MS7884_RS10165	COG0339	signal peptide processing
MS7884_RS10170	COG0742	ribosomal rna small subunit methyltransferase
MS7884_RS10175	COG0589	response to stress
MS7884_RS10195	COG0306	phosphate transporter
MS7884_RS10200	COG2081	HI0933 family
MS7884_RS10265	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS10295	COG0739	heme binding
MS7884_RS10305	COG2132	Multicopper oxidase
MS7884_RS10310	COG3667	copper resistance
MS7884_RS10315	COG2372	response to copper ion
MS7884_RS10320	COG1276	copper resistance
MS7884_RS10325	COG0745	RESPONSE REGULATOR receiver
MS7884_RS10330	COG2205	protein histidine kinase activity
MS7884_RS10340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7884_RS10345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MS7884_RS10350	COG1414	Transcriptional regulator
MS7884_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS10375	COG0583	DNA-binding transcription factor activity
MS7884_RS10380	COG3479	Phenolic acid decarboxylase
MS7884_RS10425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS7884_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS10440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS7884_RS10465	COG1216	Glycosyl transferase, family 2
MS7884_RS10485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MS7884_RS10505	COG0628	permease
MS7884_RS10515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MS7884_RS10520	COG0425	Belongs to the sulfur carrier protein TusA family
MS7884_RS10525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MS7884_RS10540	COG2217	Heavy metal translocating P-type atpase
MS7884_RS10545	COG3714	YhhN family
MS7884_RS10555	COG3776	membrane
MS7884_RS10560	COG0742	ribosomal rna small subunit methyltransferase
MS7884_RS10565	COG0552	protein localization to endoplasmic reticulum
MS7884_RS10570	COG2884	Cell division ATP-binding protein ftsE
MS7884_RS10575	COG2177	Part of the ABC transporter FtsEX involved in
MS7884_RS10580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MS7884_RS10585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS7884_RS10590	COG0683	leucine binding
MS7884_RS10595	COG0456	acetyltransferase
MS7884_RS10605	COG0683	leucine binding
MS7884_RS10615	COG4177	L-phenylalanine transmembrane transporter activity
MS7884_RS10620	COG0411	ABC transporter
MS7884_RS10650	COG0584	glycerophosphoryl diester phosphodiesterase
MS7884_RS10660	COG0405	Gamma-glutamyltransferase
MS7884_RS10665	COG1247	-acetyltransferase
MS7884_RS10670	COG0673	inositol 2-dehydrogenase activity
MS7884_RS10675	COG1741	Belongs to the pirin family
MS7884_RS10680	COG1609	Transcriptional regulator
MS7884_RS10685	COG3265	gluconokinase activity
MS7884_RS10690	COG2610	gluconate transmembrane transporter activity
MS7884_RS10700	COG2095	MarC family integral membrane protein
MS7884_RS10705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MS7884_RS10710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MS7884_RS10715	COG1523	belongs to the glycosyl hydrolase 13 family
MS7884_RS10720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MS7884_RS10725	COG0297	glycogen (starch) synthase activity
MS7884_RS10730	COG0058	SHG alpha-glucan phosphorylase activity
MS7884_RS10735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MS7884_RS10740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS7884_RS10745	COG0705	Rhomboid family
MS7884_RS10750	COG1349	DNA-binding transcription factor activity
MS7884_RS10755	COG2909	trisaccharide binding
MS7884_RS10760	COG0058	SHG alpha-glucan phosphorylase activity
MS7884_RS10765	COG1640	4-alpha-glucanotransferase
MS7884_RS10770	COG2610	gluconate transmembrane transporter activity
MS7884_RS10780	COG1040	competence protein
MS7884_RS10800	COG1918	ferrous iron import across plasma membrane
MS7884_RS10805	COG2183	response to ionizing radiation
MS7884_RS10810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS7884_RS10825	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MS7884_RS10830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MS7884_RS10835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MS7884_RS10840	COG1011	Hydrolase
MS7884_RS10855	COG0494	nUDIX hydrolase
MS7884_RS10860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MS7884_RS10865	COG4972	Pilus assembly protein
MS7884_RS10885	COG4796	Type ii and iii secretion system protein
MS7884_RS10895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MS7884_RS10900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MS7884_RS10905	COG3266	domain, Protein
MS7884_RS10910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MS7884_RS10915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS7884_RS10925	COG0180	Tryptophanyl-tRNA synthetase
MS7884_RS10935	COG1648	precorrin-2 dehydrogenase activity
MS7884_RS10935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MS7884_RS10945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS7884_RS10950	COG0738	Major facilitator superfamily
MS7884_RS10965	COG2184	nucleotidyltransferase activity
MS7884_RS10975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MS7884_RS10980	COG1289	transmembrane transporter activity
MS7884_RS11000	COG1765	OsmC-like protein
MS7884_RS11005	COG3954	Phosphoribulokinase
MS7884_RS11010	COG3089	Belongs to the UPF0270 family
MS7884_RS11015	COG0429	hydrolase of the alpha beta-hydrolase fold
MS7884_RS11045	COG0679	Auxin Efflux Carrier
MS7884_RS11055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MS7884_RS11065	COG0488	(ABC) transporter
MS7884_RS11075	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS7884_RS11080	COG0475	glutathione-regulated potassium exporter activity
MS7884_RS11080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS7884_RS11085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MS7884_RS11090	COG1047	Peptidyl-prolyl cis-trans
MS7884_RS11100	COG0545	Peptidyl-prolyl cis-trans isomerase
MS7884_RS11105	COG2964	Protein conserved in bacteria
MS7884_RS11110	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MS7884_RS11115	COG2923	Belongs to the DsrF TusC family
MS7884_RS11120	COG2168	tRNA wobble position uridine thiolation
MS7884_RS11160	COG0051	transcription antitermination factor activity, RNA binding
MS7884_RS11200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MS7884_RS11205	COG0255	Belongs to the universal ribosomal protein uL29 family
MS7884_RS11235	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MS7884_RS11240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MS7884_RS11255	COG1841	ribosomal large subunit assembly
MS7884_RS11265	COG0201	protein transport
MS7884_RS11280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MS7884_RS11290	COG0202	RNA polymerase activity
MS7884_RS11305	COG0789	Transcriptional regulator
MS7884_RS11310	COG3036	rescue of stalled ribosome
MS7884_RS11315	COG1970	mechanosensitive ion channel activity
MS7884_RS11325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MS7884_RS11325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MS7884_RS11330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MS7884_RS11335	COG0242	peptide deformylase activity
MS7884_RS11340	COG0758	DNA mediated transformation
MS7884_RS11345	COG2922	Belongs to the Smg family
MS7884_RS11350	COG0551	DNA topoisomerase type I activity
MS7884_RS11355	COG0009	L-threonylcarbamoyladenylate synthase
MS7884_RS11360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MS7884_RS11370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS7884_RS11420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS11425	COG1309	transcriptional regulator
MS7884_RS11455	COG2264	protein methyltransferase activity
MS7884_RS11460	COG4145	pantothenate transmembrane transporter activity
MS7884_RS11465	COG3924	membrane
MS7884_RS11470	COG0439	Biotin carboxylase
MS7884_RS11475	COG0511	ligase activity, forming carbon-carbon bonds
MS7884_RS11480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MS7884_RS11490	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MS7884_RS11500	COG0604	alcohol dehydrogenase
MS7884_RS11505	COG2199	diguanylate cyclase activity
MS7884_RS11505	COG2200	EAL domain
MS7884_RS11510	COG1077	Cell shape determining protein MreB Mrl
MS7884_RS11515	COG1792	Involved in formation and maintenance of cell shape
MS7884_RS11520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MS7884_RS11535	COG3164	Protein of unknown function
MS7884_RS11540	COG0312	modulator of DNA gyrase
MS7884_RS11545	COG3477	response to acidic pH
MS7884_RS11550	COG0583	DNA-binding transcription factor activity
MS7884_RS11565	COG1289	transmembrane transporter activity
MS7884_RS11570	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS11575	COG2732	(Barnase) inhibitor
MS7884_RS11585	COG1438	arginine binding
MS7884_RS11595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS7884_RS11600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS7884_RS11605	COG3105	Protein conserved in bacteria
MS7884_RS11610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MS7884_RS11625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MS7884_RS11635	COG0625	glutathione transferase activity
MS7884_RS11640	COG2969	positive regulation of protein catabolic process
MS7884_RS11645	COG2186	Transcriptional regulator
MS7884_RS11650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS7884_RS11665	COG2731	YhcH YjgK YiaL family protein
MS7884_RS11670	COG0402	S-adenosylhomocysteine deaminase activity
MS7884_RS11675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS7884_RS11680	COG0493	'glutamate synthase
MS7884_RS11685	COG0070	glutamate synthase
MS7884_RS11685	COG0067	glutamate synthase
MS7884_RS11685	COG0069	glutamate synthase activity
MS7884_RS11695	COG1242	4 iron, 4 sulfur cluster binding
MS7884_RS11700	COG0433	COG0433 Predicted ATPase
MS7884_RS11710	COG1064	alcohol dehydrogenase
MS7884_RS11725	COG2927	DNA polymerase III (CHI subunit)
MS7884_RS11730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MS7884_RS11735	COG0795	lipopolysaccharide-transporting ATPase activity
MS7884_RS11740	COG0795	lipopolysaccharide-transporting ATPase activity
MS7884_RS11745	COG5002	protein histidine kinase activity
MS7884_RS11745	COG2198	Histidine kinase
MS7884_RS11745	COG0784	Response regulator, receiver
MS7884_RS11750	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MS7884_RS11760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS11780	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MS7884_RS11785	COG1137	ATPase activity
MS7884_RS11790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MS7884_RS11795	COG3117	lipopolysaccharide transmembrane transporter activity
MS7884_RS11800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MS7884_RS11810	COG0530	calcium, potassium:sodium antiporter activity
MS7884_RS11815	COG1127	ABC transporter
MS7884_RS11820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MS7884_RS11825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MS7884_RS11830	COG2854	intermembrane phospholipid transfer
MS7884_RS11835	COG3113	response to antibiotic
MS7884_RS11840	COG5007	Belongs to the BolA IbaG family
MS7884_RS11845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MS7884_RS11850	COG3423	Transcriptional regulator
MS7884_RS11855	COG0142	geranyltranstransferase activity
MS7884_RS11860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MS7884_RS11870	COG0697	spore germination
MS7884_RS11875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MS7884_RS11880	COG0642	Histidine kinase
MS7884_RS11885	COG0745	RESPONSE REGULATOR receiver
MS7884_RS11890	COG2027	D-alanyl-D-alanine carboxypeptidase
MS7884_RS11900	COG1534	Rna-binding protein
MS7884_RS11905	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MS7884_RS11915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MS7884_RS11920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS7884_RS11925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MS7884_RS11935	COG0137	argininosuccinate synthase activity
MS7884_RS11955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MS7884_RS11960	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MS7884_RS11965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MS7884_RS11970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MS7884_RS11985	COG0513	Belongs to the DEAD box helicase family
MS7884_RS11990	COG0814	amino acid
MS7884_RS11995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS12000	COG0826	peptidase U32
MS7884_RS12005	COG0826	peptidase U32
MS7884_RS12010	COG3154	lipid carrier protein
MS7884_RS12015	COG3153	acetyltransferase
MS7884_RS12020	COG2827	Endonuclease containing a URI domain
MS7884_RS12025	COG3787	Belongs to the UPF0306 family
MS7884_RS12030	COG0693	protein deglycase activity
MS7884_RS12035	COG0702	epimerase
MS7884_RS12040	COG0701	Predicted permease
MS7884_RS12045	COG2823	Periplasmic or secreted lipoprotein
MS7884_RS12050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MS7884_RS12055	COG0792	nuclease activity
MS7884_RS12060	COG3107	peptidoglycan biosynthetic process
MS7884_RS12070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MS7884_RS12085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS12085	COG1263	PTS System
MS7884_RS12090	COG0191	fructose-bisphosphate aldolase activity
MS7884_RS12095	COG2222	sugar isomerase
MS7884_RS12100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS7884_RS12110	COG3716	PTS system mannose fructose sorbose family IID component
MS7884_RS12120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS12135	COG1349	DNA-binding transcription factor activity
MS7884_RS12140	COG2721	sulfolactate sulfo-lyase activity
MS7884_RS12150	COG2084	Dehydrogenase
MS7884_RS12155	COG1929	Belongs to the glycerate kinase type-1 family
MS7884_RS12165	COG0583	DNA-binding transcription factor activity
MS7884_RS12170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS7884_RS12175	COG0814	amino acid
MS7884_RS12180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MS7884_RS12185	COG1882	Formate acetyltransferase
MS7884_RS12190	COG0814	amino acid
MS7884_RS12200	COG1741	Belongs to the pirin family
MS7884_RS12205	COG0583	DNA-binding transcription factor activity
MS7884_RS12210	COG3152	Membrane
MS7884_RS12215	COG0435	Glutathione S-transferase
MS7884_RS12220	COG2259	Doxx family
MS7884_RS12230	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
MS7884_RS12235	COG4575	ribosome binding
MS7884_RS12240	COG1422	Protein of unknown function (DUF1090)
MS7884_RS12250	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS12255	COG2186	Transcriptional regulator
MS7884_RS12260	COG2271	Major facilitator Superfamily
MS7884_RS12270	COG2721	sulfolactate sulfo-lyase activity
MS7884_RS12280	COG0861	Integral membrane protein TerC family
MS7884_RS12285	COG0673	inositol 2-dehydrogenase activity
MS7884_RS12290	COG1451	nucleotide metabolic process
MS7884_RS12300	COG1902	pentaerythritol trinitrate reductase activity
MS7884_RS12300	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS7884_RS12305	COG1070	Carbohydrate kinase
MS7884_RS12310	COG2390	Transcriptional regulator
MS7884_RS12315	COG1129	ABC transporter
MS7884_RS12320	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS12325	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS12330	COG1879	ABC-type sugar transport system periplasmic component
MS7884_RS12335	COG1830	Aldolase
MS7884_RS12340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MS7884_RS12355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MS7884_RS12360	COG0840	transmembrane signaling receptor activity
MS7884_RS12365	COG0840	transmembrane signaling receptor activity
MS7884_RS12370	COG1695	Transcriptional regulator
MS7884_RS12375	COG2375	cellular response to nickel ion
MS7884_RS12390	COG3663	DNA glycosylase
MS7884_RS12400	COG0358	DNA primase activity
MS7884_RS12405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MS7884_RS12415	COG2197	response regulator
MS7884_RS12425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MS7884_RS12430	COG0830	nickel cation binding
MS7884_RS12440	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MS7884_RS12445	COG0804	urea catabolic process
MS7884_RS12450	COG0832	Belongs to the urease beta subunit family
MS7884_RS12455	COG0831	urea catabolic process
MS7884_RS12460	COG0829	nickel cation binding
MS7884_RS12465	COG0477	Major facilitator Superfamily
MS7884_RS12475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MS7884_RS12485	COG0617	tRNA 3'-terminal CCA addition
MS7884_RS12490	COG4991	sh3 domain protein
MS7884_RS12500	COG3025	triphosphatase activity
MS7884_RS12510	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MS7884_RS12510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MS7884_RS12520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MS7884_RS12525	COG3539	Fimbrial protein
MS7884_RS12530	COG3121	Chaperone
MS7884_RS12540	COG3539	Fimbrial protein
MS7884_RS12550	COG3384	dioxygenase
MS7884_RS12555	COG0754	glutathionylspermidine amidase activity
MS7884_RS12575	COG0494	nUDIX hydrolase
MS7884_RS12580	COG3151	Protein conserved in bacteria
MS7884_RS12585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MS7884_RS12590	COG3150	esterase
MS7884_RS12595	COG0187	DNA topoisomerase II activity
MS7884_RS12600	COG4774	siderophore transport
MS7884_RS12605	COG1120	ATPase activity
MS7884_RS12610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS12615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS12640	COG2211	Major facilitator Superfamily
MS7884_RS12645	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MS7884_RS12650	COG1652	LysM domain
MS7884_RS12655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MS7884_RS12660	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS7884_RS12675	COG3111	PFAM Bacterial OB fold (BOF) protein
MS7884_RS12695	COG1032	radical SAM domain protein
MS7884_RS12730	COG2963	transposase activity
MS7884_RS12785	COG3344	reverse transcriptase
MS7884_RS12790	COG2801	Transposase and inactivated derivatives
MS7884_RS12825	COG2814	Major facilitator Superfamily
MS7884_RS12830	COG0543	2 iron, 2 sulfur cluster binding
MS7884_RS12845	COG0418	dihydroorotase activity
MS7884_RS12860	COG2801	Transposase and inactivated derivatives
MS7884_RS12875	COG0110	maltose O-acetyltransferase activity
MS7884_RS12880	COG2223	nitrite transmembrane transporter activity
MS7884_RS12890	COG1609	Transcriptional regulator
MS7884_RS12925	COG3436	PFAM IS66 Orf2 family protein
MS7884_RS12935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS12940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS12945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MS7884_RS12950	COG4772	TonB-dependent receptor
MS7884_RS12955	COG3712	iron ion homeostasis
MS7884_RS12970	COG1032	radical SAM domain protein
MS7884_RS12980	COG1979	alcohol dehydrogenase
MS7884_RS12985	COG2207	Transcriptional regulator
MS7884_RS12990	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS12995	COG0626	cystathionine gamma-synthase activity
MS7884_RS13010	COG0848	biopolymer transport protein
MS7884_RS13030	COG2862	Uncharacterized protein family, UPF0114
MS7884_RS13035	COG0667	Aldo Keto reductase
MS7884_RS13040	COG0840	transmembrane signaling receptor activity
MS7884_RS13045	COG1349	DNA-binding transcription factor activity
MS7884_RS13050	COG0625	glutathione transferase activity
MS7884_RS13055	COG0754	glutathionylspermidine amidase activity
MS7884_RS13065	COG1215	transferase activity, transferring glycosyl groups
MS7884_RS13070	COG0726	polysaccharide deacetylase
MS7884_RS13070	COG1649	PFAM Uncharacterised BCR, COG1649
MS7884_RS13075	COG0457	Tetratricopeptide repeat
MS7884_RS13095	COG2197	response regulator
MS7884_RS13100	COG2205	protein histidine kinase activity
MS7884_RS13100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS13120	COG1811	Na channel or pump
MS7884_RS13125	COG1982	Orn Lys Arg decarboxylase major
MS7884_RS13140	COG3493	citrate carrier protein
MS7884_RS13145	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS7884_RS13155	COG3052	prosthetic group binding
MS7884_RS13175	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
MS7884_RS13180	COG2211	Major facilitator Superfamily
MS7884_RS13185	COG0741	lytic transglycosylase activity
MS7884_RS13195	COG1194	a g-specific adenine glycosylase
MS7884_RS13205	COG3171	Protein conserved in bacteria
MS7884_RS13215	COG2852	Protein conserved in bacteria
MS7884_RS13220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS7884_RS13230	COG1872	DUF167
MS7884_RS13235	COG0762	integral membrane protein
MS7884_RS13240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MS7884_RS13245	COG2805	Type II/IV secretion system protein
MS7884_RS13265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MS7884_RS13270	COG2356	endonuclease I
MS7884_RS13275	COG3091	SprT-like family
MS7884_RS13280	COG2814	Major facilitator Superfamily
MS7884_RS13300	COG1166	arginine decarboxylase activity
MS7884_RS13305	COG0010	Belongs to the arginase family
MS7884_RS13315	COG2146	nitrite reductase [NAD(P)H] activity
MS7884_RS13330	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS13335	COG1414	Transcriptional regulator
MS7884_RS13360	COG2267	carboxylic ester hydrolase activity
MS7884_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS13370	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MS7884_RS13390	COG0501	Belongs to the peptidase M48B family
MS7884_RS13395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MS7884_RS13400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS7884_RS13405	COG0126	phosphoglycerate kinase activity
MS7884_RS13410	COG0191	fructose-bisphosphate aldolase activity
MS7884_RS13415	COG0668	transmembrane transport
MS7884_RS13420	COG1279	arginine transmembrane transporter activity
MS7884_RS13425	COG2968	Membrane
MS7884_RS13430	COG0583	DNA-binding transcription factor activity
MS7884_RS13435	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MS7884_RS13445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7884_RS13450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MS7884_RS13460	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MS7884_RS13475	COG0006	proline dipeptidase activity
MS7884_RS13480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS7884_RS13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS7884_RS13490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MS7884_RS13500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MS7884_RS13500	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MS7884_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS13510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MS7884_RS13530	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS13535	COG1737	Transcriptional regulator
MS7884_RS13540	COG1272	protein, Hemolysin III
MS7884_RS13545	COG0354	folic acid binding
MS7884_RS13550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MS7884_RS13565	COG4974	Belongs to the 'phage' integrase family
MS7884_RS13575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MS7884_RS13585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MS7884_RS13590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MS7884_RS13595	COG4942	peptidase
MS7884_RS13615	COG1280	lysine exporter protein (LysE YggA)
MS7884_RS13620	COG1335	isochorismatase
MS7884_RS13625	COG2067	long-chain fatty acid transport protein
MS7884_RS13645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MS7884_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS13655	COG3111	PFAM Bacterial OB fold (BOF) protein
MS7884_RS13670	COG1546	Belongs to the CinA family
MS7884_RS13685	COG1294	oxidase, subunit
MS7884_RS13690	COG1271	oxidase subunit
MS7884_RS13695	COG3546	catalase activity
MS7884_RS13700	COG3685	Protein conserved in bacteria
MS7884_RS13705	COG3685	Protein conserved in bacteria
MS7884_RS13710	COG3729	General stress protein
MS7884_RS13715	COG3592	Divergent 4Fe-4S mono-cluster
MS7884_RS13720	COG2388	GCN5-related N-acetyl-transferase
MS7884_RS13725	COG0814	amino acid
MS7884_RS13740	COG0183	Belongs to the thiolase family
MS7884_RS13745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MS7884_RS13750	COG0823	Involved in the tonB-independent uptake of proteins
MS7884_RS13755	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MS7884_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS13765	COG2814	Major facilitator Superfamily
MS7884_RS13775	COG3842	ATPase activity
MS7884_RS13780	COG0395	ABC-type sugar transport system, permease component
MS7884_RS13785	COG1175	transmembrane transport
MS7884_RS13790	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
MS7884_RS13800	COG1794	racemase activity, acting on amino acids and derivatives
MS7884_RS13805	COG0583	DNA-binding transcription factor activity
MS7884_RS13815	COG1609	Transcriptional regulator
MS7884_RS13820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS13825	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS13830	COG2186	Transcriptional regulator
MS7884_RS13840	COG1609	Transcriptional regulator
MS7884_RS13845	COG0318	PFAM AMP-dependent synthetase and ligase
MS7884_RS13845	COG0204	Acyl-transferase
MS7884_RS13850	COG0477	Major facilitator Superfamily
MS7884_RS13855	COG0667	Aldo Keto reductase
MS7884_RS13865	COG3066	DNA modification
MS7884_RS13870	COG0494	nUDIX hydrolase
MS7884_RS13880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MS7884_RS13885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MS7884_RS13890	COG2165	general secretion pathway protein
MS7884_RS13895	COG4795	General secretion pathway protein
MS7884_RS13905	COG4967	type IV pilus modification protein PilV
MS7884_RS13910	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MS7884_RS13920	COG1074	ATP-dependent DNA helicase activity
MS7884_RS13925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MS7884_RS13930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MS7884_RS13930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MS7884_RS13935	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS7884_RS13960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MS7884_RS13965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MS7884_RS13970	COG2166	iron-sulfur cluster assembly
MS7884_RS13975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MS7884_RS13985	COG0583	DNA-binding transcription factor activity
MS7884_RS13990	COG2363	Small membrane protein
MS7884_RS13995	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MS7884_RS14005	COG1760	l-serine dehydratase
MS7884_RS14010	COG0814	amino acid
MS7884_RS14015	COG1611	Belongs to the LOG family
MS7884_RS14035	COG3098	single-species biofilm formation
MS7884_RS14040	COG0564	pseudouridine synthase activity
MS7884_RS14045	COG0716	FMN binding
MS7884_RS14055	COG2271	Major facilitator Superfamily
MS7884_RS14060	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS14065	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS14070	COG1929	Belongs to the glycerate kinase type-1 family
MS7884_RS14075	COG4999	Histidine kinase
MS7884_RS14075	COG3437	response regulator, receiver
MS7884_RS14075	COG2205	protein histidine kinase activity
MS7884_RS14075	COG3850	Histidine kinase
MS7884_RS14080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MS7884_RS14085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS7884_RS14090	COG3956	TIGRFAM MazG family protein
MS7884_RS14105	COG1737	Transcriptional regulator
MS7884_RS14110	COG1263	PTS System
MS7884_RS14110	COG2190	(PTS) system
MS7884_RS14110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS14115	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MS7884_RS14120	COG0602	queuosine metabolic process
MS7884_RS14130	COG1473	amidohydrolase
MS7884_RS14140	COG0720	synthase
MS7884_RS14145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MS7884_RS14160	COG2234	aminopeptidase activity
MS7884_RS14180	COG0529	Catalyzes the synthesis of activated sulfate
MS7884_RS14190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MS7884_RS14195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MS7884_RS14205	COG0585	pseudouridine synthase activity
MS7884_RS14220	COG1388	LysM domain
MS7884_RS14220	COG4942	peptidase
MS7884_RS14235	COG0477	Major facilitator Superfamily
MS7884_RS14250	COG0163	prenyltransferase activity
MS7884_RS14255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MS7884_RS14265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MS7884_RS14285	COG0309	Hydrogenase expression formation protein (HypE)
MS7884_RS14290	COG0409	Hydrogenase expression formation protein
MS7884_RS14295	COG0298	carbon dioxide binding
MS7884_RS14300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MS7884_RS14305	COG0375	protein maturation
MS7884_RS14320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS7884_RS14325	COG0651	ATP synthesis coupled electron transport
MS7884_RS14330	COG0650	Formate hydrogenlyase subunit 4
MS7884_RS14335	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
MS7884_RS14335	COG3261	NADH dehydrogenase
MS7884_RS14340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS7884_RS14345	COG3260	NADH ubiquinone oxidoreductase 20
MS7884_RS14355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MS7884_RS14360	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS14365	COG1263	PTS System
MS7884_RS14365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS14370	COG1609	Transcriptional regulator
MS7884_RS14375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS7884_RS14380	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MS7884_RS14385	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MS7884_RS14390	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS7884_RS14395	COG1773	rubredoxin
MS7884_RS14395	COG0426	domain, Protein
MS7884_RS14400	COG3604	Transcriptional regulator
MS7884_RS14410	COG1349	DNA-binding transcription factor activity
MS7884_RS14415	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS14420	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS14430	COG3732	PTS system glucitol sorbitol-specific
MS7884_RS14435	COG3730	PTS system glucitol sorbitol-specific
MS7884_RS14440	COG2951	lytic endotransglycosylase activity
MS7884_RS14450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7884_RS14460	COG1546	Belongs to the CinA family
MS7884_RS14475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MS7884_RS14480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MS7884_RS14510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS14515	COG1238	metal cluster binding
MS7884_RS14520	COG2918	glutathione biosynthetic process
MS7884_RS14535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MS7884_RS14540	COG2814	Major facilitator Superfamily
MS7884_RS14545	COG1566	PFAM secretion protein HlyD family protein
MS7884_RS14550	COG1846	Transcriptional regulator
MS7884_RS14555	COG2814	Major facilitator Superfamily
MS7884_RS14565	COG4176	ABC-type proline glycine betaine transport system permease component
MS7884_RS14570	COG4175	Glycine betaine
MS7884_RS14585	COG1780	Probably involved in ribonucleotide reductase function
MS7884_RS14595	COG4575	ribosome binding
MS7884_RS14620	COG0401	homolog of Blt101
MS7884_RS14625	COG0583	DNA-binding transcription factor activity
MS7884_RS14630	COG0666	response to abiotic stimulus
MS7884_RS14635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MS7884_RS14640	COG1304	FMN binding
MS7884_RS14650	COG0549	Belongs to the carbamate kinase family
MS7884_RS14655	COG0402	S-adenosylhomocysteine deaminase activity
MS7884_RS14660	COG2226	methyltransferase
MS7884_RS14675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7884_RS14680	COG3093	addiction module antidote protein HigA
MS7884_RS14685	COG3549	Plasmid maintenance system killer
MS7884_RS14690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS14720	COG2226	methyltransferase
MS7884_RS14720	COG1073	alpha beta
MS7884_RS14725	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS14735	COG2814	Major facilitator Superfamily
MS7884_RS14755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MS7884_RS14770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MS7884_RS14775	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MS7884_RS14785	COG0745	RESPONSE REGULATOR receiver
MS7884_RS14795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MS7884_RS14800	COG1677	Flagellar hook-basal body complex protein FliE
MS7884_RS14805	COG1766	The M ring may be actively involved in energy transduction
MS7884_RS14830	COG3144	bacterial-type flagellum assembly
MS7884_RS14835	COG1580	Controls the rotational direction of flagella during chemotaxis
MS7884_RS14845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MS7884_RS14850	COG3190	flagellar
MS7884_RS14860	COG1987	bacterial-type flagellum assembly
MS7884_RS14875	COG0745	RESPONSE REGULATOR receiver
MS7884_RS14900	COG3418	PFAM FlgN family protein
MS7884_RS14905	COG2747	anti-sigma28 factor FlgM
MS7884_RS14915	COG1815	bacterial-type flagellum-dependent cell motility
MS7884_RS14930	COG1749	Flagellar hook protein flgE
MS7884_RS14940	COG4786	Flagellar basal body rod
MS7884_RS14950	COG1706	bacterial-type flagellum-dependent cell motility
MS7884_RS14955	COG3951	Flagellar rod assembly protein muramidase FlgJ
MS7884_RS14955	COG1705	Flagellar rod assembly protein muramidase FlgJ
MS7884_RS14995	COG1360	Flagellar Motor Protein
MS7884_RS15005	COG0835	chemotaxis
MS7884_RS15010	COG3842	ATPase activity
MS7884_RS15025	COG0395	ABC-type sugar transport system, permease component
MS7884_RS15030	COG4209	transmembrane transport
MS7884_RS15035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS15085	COG0582	viral genome integration into host DNA
MS7884_RS15095	COG4974	Belongs to the 'phage' integrase family
MS7884_RS15130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS7884_RS15175	COG4695	Portal protein
MS7884_RS15285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS7884_RS15340	COG2867	negative regulation of translational initiation
MS7884_RS15360	COG0497	DNA recombination
MS7884_RS15365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MS7884_RS15370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MS7884_RS15375	COG4536	flavin adenine dinucleotide binding
MS7884_RS15380	COG4137	Cytochrome C assembly protein
MS7884_RS15385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MS7884_RS15395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MS7884_RS15400	COG0336	Belongs to the RNA methyltransferase TrmD family
MS7884_RS15420	COG2885	chlorophyll binding
MS7884_RS15425	COG2199	diguanylate cyclase activity
MS7884_RS15440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS7884_RS15445	COG1605	Chorismate mutase
MS7884_RS15445	COG0287	Prephenate dehydrogenase
MS7884_RS15455	COG1605	Chorismate mutase
MS7884_RS15455	COG0077	Prephenate dehydratase
MS7884_RS15460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MS7884_RS15465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS7884_RS15470	COG0564	pseudouridine synthase activity
MS7884_RS15480	COG0542	response to heat
MS7884_RS15510	COG0477	Major facilitator Superfamily
MS7884_RS15515	COG5544	Lipoprotein
MS7884_RS15520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS7884_RS15525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS15525	COG0045	succinate-CoA ligase (ADP-forming) activity
MS7884_RS15525	COG1042	CoA-binding domain protein
MS7884_RS15530	COG3148	PFAM DTW domain containing protein
MS7884_RS15535	COG3118	belongs to the thioredoxin family
MS7884_RS15545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS7884_RS15550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MS7884_RS15555	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
MS7884_RS15560	COG0513	Belongs to the DEAD box helicase family
MS7884_RS15565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MS7884_RS15570	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MS7884_RS15580	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
MS7884_RS15590	COG3086	response to oxidative stress
MS7884_RS15600	COG0681	Belongs to the peptidase S26 family
MS7884_RS15620	COG1381	Involved in DNA repair and RecF pathway recombination
MS7884_RS15625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MS7884_RS15635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS7884_RS15640	COG1737	Transcriptional regulator
MS7884_RS15645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MS7884_RS15650	COG1263	PTS System
MS7884_RS15650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS15655	COG0560	Phosphoserine phosphatase
MS7884_RS15665	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MS7884_RS15670	COG0047	phosphoribosylformylglycinamidine synthase activity
MS7884_RS15670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MS7884_RS15675	COG2205	protein histidine kinase activity
MS7884_RS15680	COG3170	Tfp pilus assembly protein FimV
MS7884_RS15685	COG2204	response regulator
MS7884_RS15690	COG0347	Belongs to the P(II) protein family
MS7884_RS15695	COG1017	nitric oxide dioxygenase activity
MS7884_RS15695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS7884_RS15710	COG2259	Doxx family
MS7884_RS15715	COG2814	Major facilitator Superfamily
MS7884_RS15720	COG3711	transcriptional antiterminator
MS7884_RS15730	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MS7884_RS15740	COG3157	Type VI secretion system effector, Hcp
MS7884_RS15760	COG1104	cysteine desulfurase activity
MS7884_RS15765	COG0822	iron-sulfur transferase activity
MS7884_RS15770	COG0316	Belongs to the HesB IscA family
MS7884_RS15775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MS7884_RS15780	COG0443	Heat shock 70 kDa protein
MS7884_RS15785	COG0633	Ferredoxin
MS7884_RS15790	COG2975	iron-sulfur cluster assembly
MS7884_RS15795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MS7884_RS15805	COG1737	Transcriptional regulator
MS7884_RS15810	COG2897	thiosulfate sulfurtransferase activity
MS7884_RS15820	COG2190	(PTS) system
MS7884_RS15820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS15820	COG1263	PTS System
MS7884_RS15825	COG2373	Large extracellular alpha-helical protein
MS7884_RS15830	COG4953	penicillin-binding protein 1C
MS7884_RS15835	COG0243	molybdopterin cofactor binding
MS7884_RS15840	COG0437	4 iron, 4 sulfur cluster binding
MS7884_RS15860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MS7884_RS15875	COG0124	histidyl-tRNA synthetase
MS7884_RS15880	COG2976	Protein conserved in bacteria
MS7884_RS15890	COG1160	GTP binding
MS7884_RS15905	COG1645	bacterial-type flagellum-dependent swarming motility
MS7884_RS15920	COG1570	exodeoxyribonuclease VII activity
MS7884_RS15925	COG0516	GMP reductase activity
MS7884_RS15925	COG0517	IMP dehydrogenase activity
MS7884_RS15945	COG3962	Belongs to the TPP enzyme family
MS7884_RS15950	COG0673	inositol 2-dehydrogenase activity
MS7884_RS15965	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS15970	COG0673	inositol 2-dehydrogenase activity
MS7884_RS15975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS15985	COG3718	enzyme involved in inositol metabolism
MS7884_RS15995	COG2200	EAL domain
MS7884_RS16010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MS7884_RS16020	COG2723	6-phospho-beta-galactosidase activity
MS7884_RS16025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MS7884_RS16030	COG2233	PERMEase
MS7884_RS16040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MS7884_RS16045	COG1446	asparaginase
MS7884_RS16060	COG1393	Belongs to the ArsC family
MS7884_RS16065	COG4783	chaperone-mediated protein folding
MS7884_RS16070	COG0628	permease
MS7884_RS16075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MS7884_RS16080	COG2716	regulation of RNA biosynthetic process
MS7884_RS16090	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MS7884_RS16095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MS7884_RS16100	COG2321	neutral zinc metallopeptidase
MS7884_RS16110	COG0400	carboxylic ester hydrolase activity
MS7884_RS16120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MS7884_RS16125	COG1393	Belongs to the ArsC family
MS7884_RS16130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS16135	COG3850	Histidine kinase
MS7884_RS16145	COG0493	'glutamate synthase
MS7884_RS16145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS7884_RS16150	COG0494	nUDIX hydrolase
MS7884_RS16155	COG5342	invasion associated locus B
MS7884_RS16160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MS7884_RS16175	COG0408	coproporphyrinogen oxidase activity
MS7884_RS16200	COG2837	iron assimilation
MS7884_RS16205	COG4150	thiosulfate binding
MS7884_RS16210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MS7884_RS16215	COG4208	sulfate ABC transporter
MS7884_RS16220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MS7884_RS16245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS16275	COG3115	cell septum assembly
MS7884_RS16280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MS7884_RS16285	COG3530	Putative quorum-sensing-regulated virulence factor
MS7884_RS16290	COG0385	Bile acid
MS7884_RS16295	COG0583	DNA-binding transcription factor activity
MS7884_RS16330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS7884_RS16335	COG3415	Transposase
MS7884_RS16340	COG3415	Transposase
MS7884_RS16355	COG2200	EAL domain
MS7884_RS16355	COG2199	diguanylate cyclase activity
MS7884_RS16360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS7884_RS16365	COG1914	H( )-stimulated, divalent metal cation uptake system
MS7884_RS16375	COG0667	Aldo Keto reductase
MS7884_RS16380	COG3961	Belongs to the TPP enzyme family
MS7884_RS16390	COG0837	glucose binding
MS7884_RS16395	COG3279	Response regulator of the LytR AlgR family
MS7884_RS16400	COG3275	phosphorelay sensor kinase activity
MS7884_RS16405	COG0436	Aminotransferase
MS7884_RS16415	COG1560	Kdo2-lipid A biosynthetic process
MS7884_RS16420	COG3706	GGDEF domain
MS7884_RS16430	COG2116	formate transmembrane transporter activity
MS7884_RS16440	COG2067	long-chain fatty acid transport protein
MS7884_RS16450	COG3691	Protein conserved in bacteria
MS7884_RS16460	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS7884_RS16460	COG1024	Enoyl-CoA hydratase
MS7884_RS16465	COG2062	phosphohistidine phosphatase, SixA
MS7884_RS16470	COG2840	Smr protein MutS2
MS7884_RS16480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MS7884_RS16490	COG0730	response to heat
MS7884_RS16495	COG3101	peptidyl-lysine hydroxylation
MS7884_RS16505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MS7884_RS16505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS7884_RS16510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS7884_RS16525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7884_RS16530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MS7884_RS16535	COG0101	tRNA pseudouridine synthase activity
MS7884_RS16540	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS16550	COG0285	dihydrofolate synthase activity
MS7884_RS16555	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MS7884_RS16560	COG1286	toxin biosynthetic process
MS7884_RS16565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MS7884_RS16570	COG0163	prenyltransferase activity
MS7884_RS16580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS16590	COG4160	amino acid transport
MS7884_RS16595	COG4598	ABC transporter
MS7884_RS16600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS16605	COG1090	epimerase
MS7884_RS16610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MS7884_RS16615	COG0625	glutathione transferase activity
MS7884_RS16620	COG0625	glutathione transferase activity
MS7884_RS16625	COG0622	Phosphoesterase
MS7884_RS16635	COG1609	Transcriptional regulator
MS7884_RS16645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS16655	COG3037	sugar-specific permease SgaT UlaA
MS7884_RS16660	COG3959	Transketolase, thiamine diphosphate binding domain
MS7884_RS16665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MS7884_RS16690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS16695	COG0490	domain, Protein
MS7884_RS16695	COG0471	metal ion transport
MS7884_RS16705	COG0436	Aminotransferase
MS7884_RS16710	COG0583	DNA-binding transcription factor activity
MS7884_RS16720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS7884_RS16750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MS7884_RS16760	COG0839	Belongs to the complex I subunit 6 family
MS7884_RS16765	COG0713	ATP synthesis coupled electron transport
MS7884_RS16770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS7884_RS16775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS7884_RS16780	COG1007	ATP synthesis coupled electron transport
MS7884_RS16785	COG0784	Response regulator, receiver
MS7884_RS16785	COG0835	chemotaxis
MS7884_RS16790	COG1234	tRNA 3'-trailer cleavage
MS7884_RS16795	COG2153	protein acetylation
MS7884_RS16800	COG4575	ribosome binding
MS7884_RS16805	COG1169	isochorismate synthase
MS7884_RS16810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MS7884_RS16815	COG0596	Alpha beta hydrolase
MS7884_RS16825	COG1441	menaquinone biosynthetic process
MS7884_RS16870	COG0247	lactate metabolic process
MS7884_RS16875	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
MS7884_RS16880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MS7884_RS16885	COG2271	Major facilitator Superfamily
MS7884_RS16890	COG0584	glycerophosphoryl diester phosphodiesterase
MS7884_RS16895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS7884_RS16910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MS7884_RS16930	COG0642	Histidine kinase
MS7884_RS16930	COG2198	Histidine kinase
MS7884_RS16935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS7884_RS16945	COG2169	Transcriptional regulator
MS7884_RS16945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS7884_RS16955	COG4615	Cyclic peptide transporter
MS7884_RS16960	COG2239	Acts as a magnesium transporter
MS7884_RS16965	COG0659	secondary active sulfate transmembrane transporter activity
MS7884_RS16970	COG0579	oxidoreductase
MS7884_RS16980	COG3182	Iron-regulated membrane protein
MS7884_RS16995	COG3082	Protein of unknown function (DUF1414)
MS7884_RS17000	COG3081	Nucleoid-associated protein
MS7884_RS17010	COG1061	Type III restriction enzyme res subunit
MS7884_RS17015	COG1187	pseudouridine synthase activity
MS7884_RS17020	COG2814	Major facilitator Superfamily
MS7884_RS17035	COG4172	Belongs to the ABC transporter superfamily
MS7884_RS17040	COG4239	(ABC) transporter, permease
MS7884_RS17045	COG4174	ABC transporter (Permease)
MS7884_RS17050	COG4166	transmembrane transport
MS7884_RS17055	COG2200	EAL domain
MS7884_RS17060	COG0791	NLP P60 protein
MS7884_RS17065	COG0671	phosphoesterase, PA-phosphatase related
MS7884_RS17070	COG0523	cobalamin synthesis protein
MS7884_RS17075	COG0246	Mannitol dehydrogenase
MS7884_RS17080	COG1312	Catalyzes the dehydration of D-mannonate
MS7884_RS17085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MS7884_RS17100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS17100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS17105	COG1105	Belongs to the carbohydrate kinase PfkB family
MS7884_RS17110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS17110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MS7884_RS17110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7884_RS17115	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MS7884_RS17120	COG2855	membrane
MS7884_RS17125	COG0583	DNA-binding transcription factor activity
MS7884_RS17135	COG0833	amino acid
MS7884_RS17140	COG4771	TonB-dependent receptor
MS7884_RS17145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MS7884_RS17150	COG0477	Major facilitator Superfamily
MS7884_RS17160	COG2311	Membrane
MS7884_RS17180	COG1129	ABC transporter
MS7884_RS17190	COG2949	membrane
MS7884_RS17195	COG0295	cytidine deaminase activity
MS7884_RS17200	COG1346	cytolysis
MS7884_RS17210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS7884_RS17220	COG1538	Outer membrane efflux protein
MS7884_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS17230	COG0586	Pfam SNARE associated Golgi protein
MS7884_RS17240	COG1686	Belongs to the peptidase S11 family
MS7884_RS17250	COG0277	FAD linked oxidase domain protein
MS7884_RS17255	COG1472	Belongs to the glycosyl hydrolase 3 family
MS7884_RS17260	COG1732	Glycine betaine
MS7884_RS17265	COG1174	glycine betaine transport
MS7884_RS17270	COG1125	glycine betaine transport
MS7884_RS17275	COG1174	glycine betaine transport
MS7884_RS17285	COG0789	Transcriptional regulator
MS7884_RS17290	COG3275	phosphorelay sensor kinase activity
MS7884_RS17300	COG4807	Protein conserved in bacteria
MS7884_RS17310	COG0489	protein tyrosine kinase activity
MS7884_RS17320	COG5455	response to cobalt ion
MS7884_RS17325	COG1596	polysaccharide export
MS7884_RS17330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MS7884_RS17335	COG0489	protein tyrosine kinase activity
MS7884_RS17335	COG3206	protein involved in exopolysaccharide biosynthesis
MS7884_RS17340	COG0076	glutamate decarboxylase activity
MS7884_RS17345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS7884_RS17360	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MS7884_RS17365	COG0351	phosphomethylpyrimidine kinase
MS7884_RS17370	COG2188	Transcriptional regulator
MS7884_RS17375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7884_RS17380	COG1397	ADP-ribosylglycohydrolase
MS7884_RS17385	COG2211	Major facilitator Superfamily
MS7884_RS17390	COG1830	Aldolase
MS7884_RS17400	COG1070	Carbohydrate kinase
MS7884_RS17425	COG1070	Carbohydrate kinase
MS7884_RS17435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS17440	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS17445	COG0747	negative chemotaxis
MS7884_RS17450	COG0601	transmembrane transport
MS7884_RS17455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7884_RS17460	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS17465	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS17470	COG1597	lipid kinase activity
MS7884_RS17485	COG0826	peptidase U32
MS7884_RS17490	COG0745	RESPONSE REGULATOR receiver
MS7884_RS17495	COG2205	protein histidine kinase activity
MS7884_RS17500	COG0477	Major facilitator Superfamily
MS7884_RS17505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS17510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS17515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS7884_RS17520	COG0443	Heat shock 70 kDa protein
MS7884_RS17525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MS7884_RS17530	COG5002	protein histidine kinase activity
MS7884_RS17530	COG3447	MASE1 domain protein
MS7884_RS17530	COG5001	Diguanylate cyclase
MS7884_RS17540	COG0717	Belongs to the dCTP deaminase family
MS7884_RS17545	COG2982	Protein involved in outer membrane biogenesis
MS7884_RS17550	COG1253	flavin adenine dinucleotide binding
MS7884_RS17565	COG3206	protein involved in exopolysaccharide biosynthesis
MS7884_RS17565	COG0489	protein tyrosine kinase activity
MS7884_RS17570	COG0463	Glycosyl transferase, family 2
MS7884_RS17575	COG1045	serine acetyltransferase
MS7884_RS17580	COG0438	transferase activity, transferring glycosyl groups
MS7884_RS17590	COG1216	Glycosyl transferase, family 2
MS7884_RS17595	COG0110	maltose O-acetyltransferase activity
MS7884_RS17600	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MS7884_RS17605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS7884_RS17610	COG1051	belongs to the nudix hydrolase family
MS7884_RS17615	COG0297	glycogen (starch) synthase activity
MS7884_RS17625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS7884_RS17630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MS7884_RS17635	COG2244	polysaccharide biosynthetic process
MS7884_RS17640	COG2327	Polysaccharide pyruvyl transferase
MS7884_RS17645	COG0438	transferase activity, transferring glycosyl groups
MS7884_RS17660	COG1088	dTDP-glucose 4,6-dehydratase activity
MS7884_RS17665	COG1091	dTDP-4-dehydrorhamnose reductase activity
MS7884_RS17670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MS7884_RS17700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MS7884_RS17710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MS7884_RS17730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MS7884_RS17730	COG0140	phosphoribosyl-ATP diphosphatase activity
MS7884_RS17735	COG0107	imidazoleglycerol-phosphate synthase activity
MS7884_RS17740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MS7884_RS17745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MS7884_RS17755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MS7884_RS17760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MS7884_RS17765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MS7884_RS17770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS7884_RS17775	COG0583	DNA-binding transcription factor activity
MS7884_RS17780	COG0531	amino acid
MS7884_RS17785	COG2925	Exonuclease
MS7884_RS17795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MS7884_RS17800	COG1289	transmembrane transporter activity
MS7884_RS17815	COG0534	Mate efflux family protein
MS7884_RS17825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MS7884_RS17830	COG0477	Major facilitator Superfamily
MS7884_RS17845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7884_RS17855	COG0589	response to stress
MS7884_RS17860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MS7884_RS17865	COG1376	ErfK ybiS ycfS ynhG family protein
MS7884_RS17885	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MS7884_RS17935	COG0583	DNA-binding transcription factor activity
MS7884_RS17960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS7884_RS17960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS7884_RS17980	COG4565	transcriptional regulatory protein
MS7884_RS17985	COG3290	protein histidine kinase activity
MS7884_RS17995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS7884_RS18000	COG1418	mRNA catabolic process
MS7884_RS18005	COG0270	DNA (cytosine-5-)-methyltransferase activity
MS7884_RS18010	COG3727	T/G mismatch-specific endonuclease activity
MS7884_RS18015	COG0697	spore germination
MS7884_RS18020	COG2354	Protein conserved in bacteria
MS7884_RS18025	COG5475	Uncharacterized small protein (DUF2158)
MS7884_RS18050	COG2197	response regulator
MS7884_RS18060	COG1987	bacterial-type flagellum assembly
MS7884_RS18100	COG1157	protein secretion by the type III secretion system
MS7884_RS18110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MS7884_RS18120	COG1677	Flagellar hook-basal body complex protein FliE
MS7884_RS18130	COG0366	Alpha amylase catalytic
MS7884_RS18140	COG1516	flagellar protein fliS
MS7884_RS18145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MS7884_RS18165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS18175	COG0765	amino acid transport
MS7884_RS18180	COG1126	abc transporter atp-binding protein
MS7884_RS18185	COG2197	response regulator
MS7884_RS18195	COG2197	response regulator
MS7884_RS18235	COG0583	DNA-binding transcription factor activity
MS7884_RS18270	COG3318	Belongs to the UPF0149 family
MS7884_RS18270	COG3012	SEC-C Motif Domain Protein
MS7884_RS18275	COG0814	amino acid
MS7884_RS18285	COG1528	Iron-storage protein
MS7884_RS18315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MS7884_RS18320	COG1528	Iron-storage protein
MS7884_RS18335	COG1879	ABC-type sugar transport system periplasmic component
MS7884_RS18345	COG1172	Belongs to the binding-protein-dependent transport system permease family
MS7884_RS18355	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MS7884_RS18395	COG1301	dicarboxylic acid transport
MS7884_RS18430	COG0840	transmembrane signaling receptor activity
MS7884_RS18445	COG0745	RESPONSE REGULATOR receiver
MS7884_RS18460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MS7884_RS18485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MS7884_RS18490	COG0018	arginyl-trna synthetase
MS7884_RS18495	COG3102	Protein conserved in bacteria
MS7884_RS18500	COG3142	Participates in the control of copper homeostasis
MS7884_RS18505	COG0500	methyltransferase
MS7884_RS18510	COG2226	methyltransferase
MS7884_RS18515	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MS7884_RS18520	COG1801	Protein of unknown function DUF72
MS7884_RS18525	COG1335	isochorismatase
MS7884_RS18535	COG0494	nUDIX hydrolase
MS7884_RS18550	COG0632	four-way junction helicase activity
MS7884_RS18555	COG2255	four-way junction helicase activity
MS7884_RS18560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7884_RS18570	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MS7884_RS18575	COG0739	heme binding
MS7884_RS18580	COG1560	Kdo2-lipid A biosynthetic process
MS7884_RS18590	COG1737	Transcriptional regulator
MS7884_RS18595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MS7884_RS18600	COG0129	dihydroxy-acid dehydratase activity
MS7884_RS18605	COG0800	Aldolase
MS7884_RS18615	COG2979	Protein of unknown function (DUF533)
MS7884_RS18620	COG1770	oligopeptidase
MS7884_RS18625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS7884_RS18630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS7884_RS18640	COG2372	response to copper ion
MS7884_RS18645	COG1276	copper resistance
MS7884_RS18660	COG2990	Protein conserved in bacteria
MS7884_RS18675	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MS7884_RS18675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MS7884_RS18680	COG3008	intermembrane lipid transfer
MS7884_RS18685	COG2995	paraquat-inducible protein a
MS7884_RS18690	COG1956	GAF domain-containing protein
MS7884_RS18695	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
MS7884_RS18705	COG0501	Belongs to the peptidase M48B family
MS7884_RS18710	COG2814	Major facilitator Superfamily
MS7884_RS18715	COG1414	Transcriptional regulator
MS7884_RS18745	COG0768	penicillin binding
MS7884_RS18750	COG2226	methyltransferase
MS7884_RS18755	COG1971	Probably functions as a manganese efflux pump
MS7884_RS18760	COG4811	Protein of unknown function (DUF986)
MS7884_RS18765	COG3716	PTS system mannose fructose sorbose family IID component
MS7884_RS18770	COG3715	PTS system
MS7884_RS18775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7884_RS18775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS18785	COG1253	flavin adenine dinucleotide binding
MS7884_RS18790	COG2200	EAL domain
MS7884_RS18795	COG1760	l-serine dehydratase
MS7884_RS18800	COG0494	nUDIX hydrolase
MS7884_RS18815	COG0251	oxidation-reduction process
MS7884_RS18820	COG1199	ATP-dependent helicase activity
MS7884_RS18825	COG1214	PFAM Peptidase M22, glycoprotease
MS7884_RS18830	COG3065	identical protein binding
MS7884_RS18835	COG0318	PFAM AMP-dependent synthetase and ligase
MS7884_RS18840	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MS7884_RS18845	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MS7884_RS18850	COG2894	cell division
MS7884_RS18855	COG0850	regulation of cytokinetic process
MS7884_RS18865	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS7884_RS18870	COG2983	Belongs to the UPF0260 family
MS7884_RS18880	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MS7884_RS18890	COG2719	SpoVR family
MS7884_RS18895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS7884_RS18900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MS7884_RS18905	COG3263	regulation of cellular component size
MS7884_RS18910	COG1619	proteins homologs of microcin C7 resistance protein MccF
MS7884_RS18915	COG0741	lytic transglycosylase activity
MS7884_RS18925	COG4774	siderophore transport
MS7884_RS18940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS7884_RS18945	COG4977	sequence-specific DNA binding
MS7884_RS19065	COG0515	serine threonine protein kinase
MS7884_RS19105	COG3209	COG3209 Rhs family protein
MS7884_RS19150	COG0012	GTP binding
MS7884_RS19155	COG0193	aminoacyl-tRNA hydrolase activity
MS7884_RS19170	COG0659	secondary active sulfate transmembrane transporter activity
MS7884_RS19185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MS7884_RS19195	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MS7884_RS19205	COG2890	protein-(glutamine-N5) methyltransferase activity
MS7884_RS19220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MS7884_RS19225	COG0387	Pfam Sodium calcium exchanger
MS7884_RS19230	COG4572	Cation transport regulator
MS7884_RS19235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MS7884_RS19245	COG0840	transmembrane signaling receptor activity
MS7884_RS19250	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MS7884_RS19255	COG3707	response regulator
MS7884_RS19260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS7884_RS19270	COG1116	anion transmembrane transporter activity
MS7884_RS19275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS7884_RS19275	COG2146	nitrite reductase [NAD(P)H] activity
MS7884_RS19280	COG0243	molybdopterin cofactor binding
MS7884_RS19285	COG4932	domain protein
MS7884_RS19290	COG2197	response regulator
MS7884_RS19295	COG3850	Histidine kinase
MS7884_RS19300	COG2223	nitrite transmembrane transporter activity
MS7884_RS19305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MS7884_RS19310	COG1140	nitrate reductase beta subunit
MS7884_RS19315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MS7884_RS19320	COG2181	nitrate reductase activity
MS7884_RS19335	COG0788	formyltetrahydrofolate deformylase activity
MS7884_RS19340	COG3012	SEC-C Motif Domain Protein
MS7884_RS19345	COG1752	Esterase of the alpha-beta hydrolase superfamily
MS7884_RS19350	COG0745	RESPONSE REGULATOR receiver
MS7884_RS19355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MS7884_RS19365	COG1435	thymidine kinase activity
MS7884_RS19370	COG1454	alcohol dehydrogenase
MS7884_RS19370	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS19375	COG2095	MarC family integral membrane protein
MS7884_RS19400	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS19405	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS19410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS7884_RS19415	COG3099	Belongs to the UPF0263 family
MS7884_RS19435	COG1280	lysine exporter protein (LysE YggA)
MS7884_RS19440	COG4974	Belongs to the 'phage' integrase family
MS7884_RS19450	COG3012	SEC-C Motif Domain Protein
MS7884_RS19470	COG2350	Protein conserved in bacteria
MS7884_RS19500	COG0727	PFAM Uncharacterised protein family (UPF0153)
MS7884_RS19505	COG3047	cAMP biosynthetic process
MS7884_RS19510	COG0425	Belongs to the sulfur carrier protein TusA family
MS7884_RS19515	COG2391	methyltransferase activity
MS7884_RS19520	COG0159	tryptophan synthase activity
MS7884_RS19525	COG0133	tryptophan synthase activity
MS7884_RS19535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS7884_RS19535	COG0512	Glutamine amidotransferase of anthranilate synthase
MS7884_RS19550	COG0009	L-threonylcarbamoyladenylate synthase
MS7884_RS19560	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MS7884_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS19570	COG0616	signal peptide processing
MS7884_RS19600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MS7884_RS19610	COG0671	phosphoesterase, PA-phosphatase related
MS7884_RS19615	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
MS7884_RS19620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MS7884_RS19625	COG0284	orotidine-5'-phosphate decarboxylase activity
MS7884_RS19630	COG0023	Translation Initiation Factor
MS7884_RS19640	COG1349	DNA-binding transcription factor activity
MS7884_RS19650	COG1024	Enoyl-CoA hydratase
MS7884_RS19655	COG5001	Diguanylate cyclase
MS7884_RS19665	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS7884_RS19665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS7884_RS19670	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MS7884_RS19675	COG0251	oxidation-reduction process
MS7884_RS19685	COG4172	Belongs to the ABC transporter superfamily
MS7884_RS19695	COG4171	peptide transport system, permease
MS7884_RS19710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MS7884_RS19715	COG1842	Phage shock protein A
MS7884_RS19725	COG1983	PspC domain protein
MS7884_RS19735	COG0366	Alpha amylase catalytic
MS7884_RS19740	COG1653	transport
MS7884_RS19745	COG1175	transmembrane transport
MS7884_RS19750	COG0395	ABC-type sugar transport system, permease component
MS7884_RS19755	COG1063	alcohol dehydrogenase
MS7884_RS19760	COG1082	Xylose isomerase domain protein TIM barrel
MS7884_RS19765	COG0673	inositol 2-dehydrogenase activity
MS7884_RS19770	COG1554	hydrolase, family 65, central catalytic
MS7884_RS19775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS19790	COG1609	Transcriptional regulator
MS7884_RS19795	COG3106	COG3106 Predicted ATPase
MS7884_RS19800	COG3768	UPF0283 membrane protein
MS7884_RS19810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MS7884_RS19815	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS19820	COG2866	Carboxypeptidase
MS7884_RS19825	COG4166	transmembrane transport
MS7884_RS19850	COG2885	chlorophyll binding
MS7884_RS19935	COG0840	transmembrane signaling receptor activity
MS7884_RS19950	COG0513	Belongs to the DEAD box helicase family
MS7884_RS19960	COG0582	viral genome integration into host DNA
MS7884_RS20025	COG1846	Transcriptional regulator
MS7884_RS20090	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MS7884_RS20095	COG0484	heat shock protein binding
MS7884_RS20120	COG3179	chitinase
MS7884_RS20255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MS7884_RS20270	COG2135	peptidase activity
MS7884_RS20275	COG0582	viral genome integration into host DNA
MS7884_RS20290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MS7884_RS20300	COG0674	pyruvate-flavodoxin oxidoreductase activity
MS7884_RS20300	COG1013	pyruvate-flavodoxin oxidoreductase activity
MS7884_RS20300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MS7884_RS20300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS7884_RS20305	COG3042	response to heat
MS7884_RS20310	COG3187	Heat shock protein
MS7884_RS20320	COG1294	oxidase, subunit
MS7884_RS20325	COG1271	oxidase subunit
MS7884_RS20335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7884_RS20340	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS20350	COG3615	Tellurite resistance protein tehB
MS7884_RS20355	COG3615	Tellurite resistance protein tehB
MS7884_RS20385	COG0747	negative chemotaxis
MS7884_RS20395	COG3238	Protein conserved in bacteria
MS7884_RS20400	COG1247	-acetyltransferase
MS7884_RS20410	COG2130	NADP-dependent
MS7884_RS20415	COG1802	Transcriptional regulator
MS7884_RS20420	COG4772	TonB-dependent receptor
MS7884_RS20450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS20455	COG1473	amidohydrolase
MS7884_RS20460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS20465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MS7884_RS20480	COG1126	abc transporter atp-binding protein
MS7884_RS20490	COG0625	glutathione transferase activity
MS7884_RS20495	COG1942	4-Oxalocrotonate Tautomerase
MS7884_RS20500	COG1560	Kdo2-lipid A biosynthetic process
MS7884_RS20510	COG0640	Transcriptional regulator
MS7884_RS20520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS7884_RS20525	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MS7884_RS20530	COG2181	nitrate reductase activity
MS7884_RS20535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MS7884_RS20540	COG1140	nitrate reductase beta subunit
MS7884_RS20545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MS7884_RS20550	COG2223	nitrite transmembrane transporter activity
MS7884_RS20575	COG3383	formate dehydrogenase (NAD+) activity
MS7884_RS20575	COG0243	molybdopterin cofactor binding
MS7884_RS20580	COG0243	molybdopterin cofactor binding
MS7884_RS20580	COG3383	formate dehydrogenase (NAD+) activity
MS7884_RS20585	COG0437	4 iron, 4 sulfur cluster binding
MS7884_RS20590	COG2864	formate dehydrogenase
MS7884_RS20610	COG2814	Major facilitator Superfamily
MS7884_RS20615	COG1252	NADH dehydrogenase
MS7884_RS20625	COG1064	alcohol dehydrogenase
MS7884_RS20630	COG0488	(ABC) transporter
MS7884_RS20635	COG0281	malic enzyme
MS7884_RS20665	COG1764	response to oxidative stress
MS7884_RS20675	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS20680	COG4608	Belongs to the ABC transporter superfamily
MS7884_RS20685	COG0444	Belongs to the ABC transporter superfamily
MS7884_RS20690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7884_RS20695	COG0601	transmembrane transport
MS7884_RS20700	COG0747	negative chemotaxis
MS7884_RS20705	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MS7884_RS20720	COG2200	EAL domain
MS7884_RS20750	COG0840	transmembrane signaling receptor activity
MS7884_RS20765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS7884_RS20770	COG1649	PFAM Uncharacterised BCR, COG1649
MS7884_RS20775	COG4628	conserved protein (DUF2132)
MS7884_RS20780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MS7884_RS20785	COG0583	DNA-binding transcription factor activity
MS7884_RS20795	COG0583	DNA-binding transcription factor activity
MS7884_RS20805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7884_RS20810	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS20820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MS7884_RS20855	COG2814	Major facilitator Superfamily
MS7884_RS20885	COG2801	Transposase and inactivated derivatives
MS7884_RS20925	COG1349	DNA-binding transcription factor activity
MS7884_RS20930	COG0494	nUDIX hydrolase
MS7884_RS20950	COG0596	Alpha beta hydrolase
MS7884_RS20975	COG3781	membrane
MS7884_RS20990	COG3706	GGDEF domain
MS7884_RS21000	COG2066	Belongs to the glutaminase family
MS7884_RS21010	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS21015	COG0583	DNA-binding transcription factor activity
MS7884_RS21030	COG2814	Major facilitator Superfamily
MS7884_RS21045	COG1846	Transcriptional regulator
MS7884_RS21060	COG0697	spore germination
MS7884_RS21065	COG2814	Major facilitator Superfamily
MS7884_RS21070	COG3443	Belongs to the bacterial solute-binding protein 9 family
MS7884_RS21080	COG1129	ABC transporter
MS7884_RS21100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MS7884_RS21125	COG0826	peptidase U32
MS7884_RS21130	COG1396	sequence-specific DNA binding
MS7884_RS21135	COG3135	benzoate transporter
MS7884_RS21155	COG0747	negative chemotaxis
MS7884_RS21160	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS7884_RS21165	COG0500	methyltransferase
MS7884_RS21170	COG1275	C4-dicarboxylate transporter malic acid transport protein
MS7884_RS21175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS7884_RS21180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS21185	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
MS7884_RS21195	COG0436	Aminotransferase
MS7884_RS21205	COG2272	Belongs to the type-B carboxylesterase lipase family
MS7884_RS21210	COG5383	Protein conserved in bacteria
MS7884_RS21215	COG0583	DNA-binding transcription factor activity
MS7884_RS21220	COG0840	transmembrane signaling receptor activity
MS7884_RS21280	COG2274	protein secretion by the type I secretion system
MS7884_RS21295	COG1349	DNA-binding transcription factor activity
MS7884_RS21300	COG0673	inositol 2-dehydrogenase activity
MS7884_RS21305	COG3038	cytochrome b561
MS7884_RS21310	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS21315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MS7884_RS21330	COG1538	Outer membrane efflux protein
MS7884_RS21335	COG1643	Atp-dependent helicase
MS7884_RS21345	COG0564	pseudouridine synthase activity
MS7884_RS21350	COG3122	Protein conserved in bacteria
MS7884_RS21395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MS7884_RS21410	COG0300	oxidoreductase activity
MS7884_RS21430	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MS7884_RS21440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS7884_RS21445	COG3327	negative regulation of DNA-templated transcription, initiation
MS7884_RS21450	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MS7884_RS21455	COG0183	Belongs to the thiolase family
MS7884_RS21460	COG2050	protein possibly involved in aromatic compounds catabolism
MS7884_RS21465	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS7884_RS21470	COG1024	Enoyl-CoA hydratase
MS7884_RS21475	COG1024	Enoyl-CoA hydratase
MS7884_RS21480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS7884_RS21485	COG2151	metal-sulfur cluster biosynthetic enzyme
MS7884_RS21490	COG3396	Phenylacetate-CoA oxygenase
MS7884_RS21495	COG3460	Phenylacetate-CoA oxygenase
MS7884_RS21500	COG3396	Phenylacetate-CoA oxygenase
MS7884_RS21505	COG2030	dehydratase
MS7884_RS21505	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS21510	COG3733	amine oxidase
MS7884_RS21515	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MS7884_RS21520	COG4251	negative regulation of phosphorylation
MS7884_RS21520	COG2203	Gaf domain
MS7884_RS21520	COG5001	Diguanylate cyclase
MS7884_RS21520	COG3706	GGDEF domain
MS7884_RS21525	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS21530	COG2207	Transcriptional regulator
MS7884_RS21535	COG3784	Protein of unknown function (DUF1318)
MS7884_RS21545	COG2911	Protein conserved in bacteria
MS7884_RS21550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MS7884_RS21570	COG4993	Dehydrogenase
MS7884_RS21580	COG0814	amino acid
MS7884_RS21590	COG1176	ABC-type spermidine putrescine transport system, permease component I
MS7884_RS21595	COG0725	ABC transporter, periplasmic molybdate-binding protein
MS7884_RS21605	COG4773	Receptor
MS7884_RS21620	COG4221	oxidoreductase activity
MS7884_RS21625	COG1802	Transcriptional regulator
MS7884_RS21630	COG0589	response to stress
MS7884_RS21640	COG0246	Mannitol dehydrogenase
MS7884_RS21650	COG1904	glucuronate isomerase
MS7884_RS21655	COG0477	Major facilitator Superfamily
MS7884_RS21660	COG1063	alcohol dehydrogenase
MS7884_RS21665	COG4948	Mandelate Racemase Muconate Lactonizing
MS7884_RS21680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS21700	COG0243	molybdopterin cofactor binding
MS7884_RS21705	COG0437	4 iron, 4 sulfur cluster binding
MS7884_RS21710	COG3302	dmso reductase anchor subunit
MS7884_RS21715	COG3381	protein complex oligomerization
MS7884_RS21720	COG3141	response to X-ray
MS7884_RS21780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MS7884_RS21785	COG1940	carbohydrate kinase activity
MS7884_RS21790	COG0583	DNA-binding transcription factor activity
MS7884_RS21795	COG2814	Major facilitator Superfamily
MS7884_RS21800	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MS7884_RS21815	COG3591	Belongs to the peptidase S1B family
MS7884_RS21820	COG2076	Multidrug Resistance protein
MS7884_RS21825	COG2076	Multidrug Resistance protein
MS7884_RS21835	COG0628	permease
MS7884_RS21845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7884_RS21850	COG0384	phenazine biosynthesis protein PhzF
MS7884_RS21855	COG1403	HNH endonuclease
MS7884_RS21865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MS7884_RS21905	COG4993	Dehydrogenase
MS7884_RS21920	COG0667	Aldo Keto reductase
MS7884_RS21930	COG2840	Smr protein MutS2
MS7884_RS21935	COG0583	DNA-binding transcription factor activity
MS7884_RS21945	COG1473	amidohydrolase
MS7884_RS21955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MS7884_RS21960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS7884_RS21970	COG0589	response to stress
MS7884_RS21975	COG0668	transmembrane transport
MS7884_RS21980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MS7884_RS21985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MS7884_RS21995	COG0531	amino acid
MS7884_RS22000	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS22005	COG3136	membrane protein required for alginate biosynthesis
MS7884_RS22010	COG0745	RESPONSE REGULATOR receiver
MS7884_RS22020	COG1278	Cold shock
MS7884_RS22030	COG2205	protein histidine kinase activity
MS7884_RS22045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS7884_RS22045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS7884_RS22055	COG5339	Protein conserved in bacteria
MS7884_RS22060	COG1609	Transcriptional regulator
MS7884_RS22065	COG1263	PTS System
MS7884_RS22065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7884_RS22070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MS7884_RS22075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MS7884_RS22080	COG0673	inositol 2-dehydrogenase activity
MS7884_RS22130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MS7884_RS22135	COG3104	oligopeptide transport
MS7884_RS22140	COG0625	glutathione transferase activity
MS7884_RS22145	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MS7884_RS22150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MS7884_RS22155	COG0259	pyridoxamine-phosphate oxidase activity
MS7884_RS22160	COG3895	Periplasmic Protein
MS7884_RS22165	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MS7884_RS22175	COG3706	GGDEF domain
MS7884_RS22190	COG1566	PFAM secretion protein HlyD family protein
MS7884_RS22195	COG1289	transmembrane transporter activity
MS7884_RS22200	COG2032	superoxide dismutase activity
MS7884_RS22205	COG4989	oxidoreductase activity
MS7884_RS22210	COG3313	Fe-S protein
MS7884_RS22215	COG2194	sulfuric ester hydrolase activity
MS7884_RS22220	COG1309	transcriptional regulator
MS7884_RS22225	COG1902	pentaerythritol trinitrate reductase activity
MS7884_RS22230	COG0346	lactoylglutathione lyase activity
MS7884_RS22240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MS7884_RS22245	COG0791	NLP P60 protein
MS7884_RS22255	COG2814	Major facilitator Superfamily
MS7884_RS22275	COG0583	DNA-binding transcription factor activity
MS7884_RS22280	COG2814	Major facilitator Superfamily
MS7884_RS22285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MS7884_RS22290	COG0307	riboflavin synthase, alpha
MS7884_RS22310	COG0071	Belongs to the small heat shock protein (HSP20) family
MS7884_RS22325	COG4529	Protein conserved in bacteria
MS7884_RS22335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7884_RS22350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7884_RS22365	COG0765	amino acid transport
MS7884_RS22375	COG1464	Belongs to the NlpA lipoprotein family
MS7884_RS22380	COG2011	ABC-type metal ion transport system permease component
MS7884_RS22395	COG0626	cystathionine gamma-synthase activity
MS7884_RS22410	COG1376	ErfK ybiS ycfS ynhG family protein
MS7884_RS22415	COG2166	iron-sulfur cluster assembly
MS7884_RS22420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MS7884_RS22425	COG0719	Fe-S assembly protein
MS7884_RS22430	COG0396	ATPase activity
MS7884_RS22435	COG0719	Fe-S assembly protein
MS7884_RS22440	COG0316	Belongs to the HesB IscA family
MS7884_RS22450	COG0789	Transcriptional regulator
MS7884_RS22455	COG2200	EAL domain
MS7884_RS22475	COG3383	formate dehydrogenase (NAD+) activity
MS7884_RS22500	COG3121	Chaperone
MS7884_RS22515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS7884_RS22525	COG2050	protein possibly involved in aromatic compounds catabolism
MS7884_RS22530	COG0277	FAD linked oxidase domain protein
MS7884_RS22530	COG0247	lactate metabolic process
MS7884_RS22535	COG0628	permease
MS7884_RS22545	COG1472	Belongs to the glycosyl hydrolase 3 family
MS7884_RS22550	COG2211	Major facilitator Superfamily
MS7884_RS22555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS7884_RS22555	COG0574	Belongs to the PEP-utilizing enzyme family
MS7884_RS22560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MS7884_RS22565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS7884_RS22570	COG4256	Hemin uptake protein
MS7884_RS22580	COG3720	iron ion transport
MS7884_RS22585	COG4558	Periplasmic binding protein
MS7884_RS22590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7884_RS22600	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MS7884_RS22610	COG0791	NLP P60 protein
MS7884_RS22620	COG0386	Belongs to the glutathione peroxidase family
MS7884_RS22630	COG0776	regulation of translation
MS7884_RS22635	COG0072	phenylalanine-tRNA ligase activity
MS7884_RS22635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS7884_RS22640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MS7884_RS22685	COG3137	Salt-induced outer membrane protein
MS7884_RS22690	COG1105	Belongs to the carbohydrate kinase PfkB family
MS7884_RS22700	COG3001	Fructosamine kinase
MS7884_RS22710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7884_RS22715	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS22720	COG1988	membrane-bound metal-dependent
MS7884_RS22725	COG1823	symporter activity
MS7884_RS22735	COG0753	catalase activity
MS7884_RS22740	COG3394	polysaccharide catabolic process
MS7884_RS22745	COG1486	melibiose metabolic process
MS7884_RS22750	COG2169	Transcriptional regulator
MS7884_RS22750	COG1917	Cupin 2, conserved barrel domain protein
MS7884_RS22755	COG1447	Phosphotransferase system cellobiose-specific component IIA
MS7884_RS22760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS22765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MS7884_RS22770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS7884_RS22780	COG0322	excinuclease ABC activity
MS7884_RS22790	COG3678	ATP-independent chaperone mediated protein folding
MS7884_RS22805	COG3724	N-succinylarginine dihydrolase activity
MS7884_RS22810	COG1012	belongs to the aldehyde dehydrogenase family
MS7884_RS22815	COG3138	arginine N-succinyltransferase
MS7884_RS22825	COG0708	Exodeoxyribonuclease III
MS7884_RS22835	COG4134	Bacterial extracellular solute-binding protein
MS7884_RS22840	COG4135	transport system, permease component
MS7884_RS22845	COG4136	ATPase activity
MS7884_RS22850	COG2897	thiosulfate sulfurtransferase activity
MS7884_RS22855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MS7884_RS22860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS7884_RS22865	COG0494	nUDIX hydrolase
MS7884_RS22880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MS7884_RS22885	COG0709	Synthesizes selenophosphate from selenide and ATP
MS7884_RS22895	COG0778	Nitroreductase
MS7884_RS22900	COG0616	signal peptide processing
MS7884_RS22905	COG0252	asparaginase activity
MS7884_RS22910	COG1335	isochorismatase
MS7884_RS22920	COG3139	Protein of unknown function (DUF1315)
MS7884_RS22940	COG3713	MltA-interacting MipA family protein
MS7884_RS22945	COG2766	serine protein kinase
MS7884_RS22950	COG2718	Belongs to the UPF0229 family
MS7884_RS22955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS7884_RS23000	COG1196	nuclear chromosome segregation
MS7884_RS23050	COG1030	water channel activity
MS7884_RS23070	COG4220	transposase activity
MS7884_RS23090	COG3646	Phage regulatory protein
MS7884_RS23135	COG3179	chitinase
MS7884_RS23155	COG1403	HNH endonuclease
MS7884_RS23165	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MS7884_RS23250	COG0582	viral genome integration into host DNA
MS7884_RS23255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS7884_RS23265	COG2211	Major facilitator Superfamily
MS7884_RS23275	COG2707	UPF0756 membrane protein
MS7884_RS23280	COG2207	Transcriptional regulator
MS7884_RS23285	COG2807	transmembrane transport
MS7884_RS23290	COG0504	CTP synthase activity
MS7884_RS23295	COG3189	MarR family transcriptional regulator
MS7884_RS23305	COG3042	response to heat
MS7884_RS23315	COG2203	Gaf domain
MS7884_RS23315	COG2199	diguanylate cyclase activity
MS7884_RS23330	COG2261	transglycosylase associated protein
MS7884_RS23340	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MS7884_RS23350	COG0538	isocitrate dehydrogenase activity
MS7884_RS23355	COG1187	pseudouridine synthase activity
MS7884_RS23370	COG2915	High frequency lysogenization protein hflD homolog
MS7884_RS23375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MS7884_RS23390	COG2205	protein histidine kinase activity
MS7884_RS23395	COG2850	peptidyl-arginine hydroxylation
MS7884_RS23435	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MS7884_RS23445	COG4591	ABC-type transport system involved in lipoprotein release permease component
MS7884_RS23450	COG1136	(ABC) transporter
MS7884_RS23455	COG4591	ABC-type transport system involved in lipoprotein release permease component
MS7884_RS23460	COG4763	Acyl-transferase
MS7884_RS23465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MS7884_RS23470	COG1376	ErfK ybiS ycfS ynhG family protein
MS7884_RS23470	COG1388	LysM domain
MS7884_RS23480	COG1309	transcriptional regulator
MS7884_RS23485	COG3134	Outer membrane lipoprotein
MS7884_RS23490	COG1252	NADH dehydrogenase
MS7884_RS23495	COG3150	esterase
MS7884_RS23510	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
MS7884_RS23515	COG5633	Lipoprotein
MS7884_RS23520	COG0537	adenosine 5'-monophosphoramidase activity
MS7884_RS23525	COG4773	Receptor
MS7884_RS23535	COG0084	hydrolase, TatD family'
MS7884_RS23540	COG0470	DNA polymerase III
MS7884_RS23545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MS7884_RS23550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MS7884_RS23555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MS7884_RS23610	COG0789	Transcriptional regulator
MS7884_RS23760	COG1196	nuclear chromosome segregation
MS7884_RS23780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7884_RS23820	COG1252	NADH dehydrogenase
MS7884_RS23840	COG1454	alcohol dehydrogenase
MS7884_RS23850	COG1294	oxidase, subunit
MS7884_RS23875	COG2194	sulfuric ester hydrolase activity
MS7884_RS23990	COG2801	Transposase and inactivated derivatives
MS7884_RS24050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS7884_RS24050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MS7884_RS24070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS7884_RS24085	COG3157	Type VI secretion system effector, Hcp
MS7884_RS24245	COG2026	Addiction module toxin, RelE StbE family
MS7884_RS24250	COG3077	Addiction module antitoxin, RelB DinJ family
MS7884_RS24260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MS7884_RS24275	COG3547	Transposase (IS116 IS110 IS902 family)
MS7884_RS24280	COG2801	Transposase and inactivated derivatives
MS7884_RS24365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MS7884_RS24450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MS7884_RS24500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS7884_RS24560	COG1660	Displays ATPase and GTPase activities
MS7884_RS24580	COG3173	Aminoglycoside phosphotransferase
MS7884_RS24610	COG1695	Transcriptional regulator
MS7884_RS24645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MS7884_RS24850	COG2890	protein-(glutamine-N5) methyltransferase activity
MS7884_RS24915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MS7884_RS25000	COG1192	Involved in chromosome partitioning
MS7884_RS25090	COG0210	DNA helicase
MS7884_RS25230	COG4245	von Willebrand factor, type A
MS7884_RS25235	COG4245	von Willebrand factor, type A
MS7884_RS25265	COG1358	cellular component organization or biogenesis
MS7884_RS25390	COG3550	peptidyl-serine autophosphorylation
MS7884_RS25415	COG0789	Transcriptional regulator
MS7884_RS25470	COG1192	Involved in chromosome partitioning
MS7884_RS25525	COG4372	Transposase
MS7884_RS25570	COG1902	pentaerythritol trinitrate reductase activity
MS7884_RS25575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MS7884_RS25580	COG1028	Short-chain dehydrogenase reductase Sdr
MS7884_RS25585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MS7884_RS25600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS7884_RS25655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MS7884_RS25730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MS7884_RS25740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MS7884_RS25750	COG0589	response to stress
MS7884_RS25755	COG0659	secondary active sulfate transmembrane transporter activity
MS7884_RS25765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MS7884_RS25770	COG1393	Belongs to the ArsC family
MS7884_RS25775	COG0431	NADPH-dependent FMN reductase
MS7884_RS25810	COG4680	protein conserved in bacteria
MS7884_RS26000	COG0330	HflC and HflK could
MS7884_RS26090	COG2026	Addiction module toxin, RelE StbE family
MS7884_RS26095	COG3077	Addiction module antitoxin, RelB DinJ family
MS7884_RS26145	COG2814	Major facilitator Superfamily
MS7884_RS26160	COG3111	PFAM Bacterial OB fold (BOF) protein
MS7884_RS26165	COG2801	Transposase and inactivated derivatives
MS7884_RS26185	COG1475	DNA binding