locus-tag	class	description
JLF40_RS00010	COG0592	DNA-directed DNA polymerase activity
JLF40_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JLF40_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS00030	COG3321	synthase
JLF40_RS00030	COG0604	alcohol dehydrogenase
JLF40_RS00035	COG0561	phosphatase activity
JLF40_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
JLF40_RS00045	COG5645	(Lipo)protein
JLF40_RS00055	COG0071	Belongs to the small heat shock protein (HSP20) family
JLF40_RS00060	COG2985	domain, Protein
JLF40_RS00065	COG2188	Transcriptional regulator
JLF40_RS00080	COG2149	membrane
JLF40_RS00095	COG2610	gluconate transmembrane transporter activity
JLF40_RS00100	COG0583	DNA-binding transcription factor activity
JLF40_RS00110	COG2814	Major facilitator Superfamily
JLF40_RS00145	COG0028	Belongs to the TPP enzyme family
JLF40_RS00150	COG0440	acetolactate synthase activity
JLF40_RS00155	COG2197	response regulator
JLF40_RS00185	COG0697	spore germination
JLF40_RS00190	COG4580	involved in the transport of maltose and maltodextrins
JLF40_RS00195	COG1447	Phosphotransferase system cellobiose-specific component IIA
JLF40_RS00200	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS00205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS00205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS00215	COG1609	Transcriptional regulator
JLF40_RS00245	COG0454	-acetyltransferase
JLF40_RS00250	COG1464	Belongs to the NlpA lipoprotein family
JLF40_RS00255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JLF40_RS00280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JLF40_RS00285	COG3272	Protein of unknown function (DUF1722)
JLF40_RS00295	COG0789	Transcriptional regulator
JLF40_RS00310	COG3539	Fimbrial protein
JLF40_RS00320	COG3121	Chaperone
JLF40_RS00355	COG0519	Catalyzes the synthesis of GMP from XMP
JLF40_RS00375	COG2211	Major facilitator Superfamily
JLF40_RS00380	COG1501	Belongs to the glycosyl hydrolase 31 family
JLF40_RS00385	COG2982	Protein involved in outer membrane biogenesis
JLF40_RS00390	COG2233	PERMEase
JLF40_RS00395	COG0786	glutamate:sodium symporter activity
JLF40_RS00400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JLF40_RS00405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JLF40_RS00410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JLF40_RS00425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JLF40_RS00430	COG2860	membrane
JLF40_RS00435	COG1561	YicC-like family, N-terminal region
JLF40_RS00445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JLF40_RS00460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JLF40_RS00465	COG2003	Belongs to the UPF0758 family
JLF40_RS00470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JLF40_RS00475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JLF40_RS00480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JLF40_RS00485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JLF40_RS00495	COG1519	Transferase
JLF40_RS00500	COG1216	Glycosyl transferase, family 2
JLF40_RS00505	COG0438	transferase activity, transferring glycosyl groups
JLF40_RS00515	COG0859	PFAM glycosyl transferase family 9
JLF40_RS00530	COG1215	transferase activity, transferring glycosyl groups
JLF40_RS00540	COG0859	PFAM glycosyl transferase family 9
JLF40_RS00545	COG0859	PFAM glycosyl transferase family 9
JLF40_RS00560	COG1063	alcohol dehydrogenase
JLF40_RS00570	COG0438	transferase activity, transferring glycosyl groups
JLF40_RS00580	COG2861	carbohydrate metabolic process
JLF40_RS00585	COG4942	peptidase
JLF40_RS00590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JLF40_RS00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JLF40_RS00600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JLF40_RS00605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JLF40_RS00610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JLF40_RS00620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JLF40_RS00625	COG2271	Major facilitator Superfamily
JLF40_RS00630	COG1304	FMN binding
JLF40_RS00635	COG2186	Transcriptional regulator
JLF40_RS00650	COG3722	fumarate hydratase activity
JLF40_RS00660	COG2213	PTS system mannitol-specific
JLF40_RS00660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS00670	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS00675	COG0625	glutathione transferase activity
JLF40_RS00685	COG3276	selenocysteine insertion sequence binding
JLF40_RS00690	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS00695	COG0583	DNA-binding transcription factor activity
JLF40_RS00700	COG3713	MltA-interacting MipA family protein
JLF40_RS00715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JLF40_RS00730	COG3977	Valine--pyruvate aminotransferase
JLF40_RS00735	COG0366	Alpha amylase catalytic
JLF40_RS00740	COG2992	FlgJ-related protein
JLF40_RS00745	COG2207	Transcriptional regulator
JLF40_RS00745	COG1609	Transcriptional regulator
JLF40_RS00750	COG4214	carbohydrate transport
JLF40_RS00760	COG4213	ABC transporter substrate-binding protein
JLF40_RS00765	COG2115	Belongs to the xylose isomerase family
JLF40_RS00770	COG1070	Carbohydrate kinase
JLF40_RS00775	COG1335	isochorismatase
JLF40_RS00780	COG2169	Transcriptional regulator
JLF40_RS00785	COG3274	enterobacterial common antigen metabolic process
JLF40_RS00795	COG0752	glycyl-tRNA synthetase alpha subunit
JLF40_RS00800	COG0751	glycine-tRNA ligase activity
JLF40_RS00810	COG0488	(ABC) transporter
JLF40_RS00815	COG2944	sequence-specific DNA binding
JLF40_RS00825	COG1278	Cold shock
JLF40_RS00830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JLF40_RS00840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JLF40_RS00850	COG1609	Transcriptional regulator
JLF40_RS00855	COG2885	chlorophyll binding
JLF40_RS00860	COG0243	molybdopterin cofactor binding
JLF40_RS00865	COG0456	acetyltransferase
JLF40_RS00870	COG2818	Glycosylase
JLF40_RS00875	COG5571	outer membrane autotransporter
JLF40_RS00880	COG2223	nitrite transmembrane transporter activity
JLF40_RS00885	COG2194	sulfuric ester hydrolase activity
JLF40_RS00895	COG0747	negative chemotaxis
JLF40_RS00900	COG0601	transmembrane transport
JLF40_RS00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS00910	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS00915	COG4608	Belongs to the ABC transporter superfamily
JLF40_RS00920	COG1072	(Pantothenic acid kinase))
JLF40_RS00955	COG0250	Participates in transcription elongation, termination and antitermination
JLF40_RS01000	COG3706	GGDEF domain
JLF40_RS01005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JLF40_RS01010	COG2022	thiamine diphosphate biosynthetic process
JLF40_RS01015	COG2104	thiamine diphosphate biosynthetic process
JLF40_RS01020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JLF40_RS01035	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JLF40_RS01045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JLF40_RS01055	COG3068	Protein conserved in bacteria
JLF40_RS01070	COG0151	Belongs to the GarS family
JLF40_RS01105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JLF40_RS01115	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JLF40_RS01135	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JLF40_RS01140	COG3657	addiction module killer protein
JLF40_RS01145	COG1187	pseudouridine synthase activity
JLF40_RS01160	COG0527	aspartate kinase activity
JLF40_RS01185	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JLF40_RS01190	COG3223	Belongs to the PsiE family
JLF40_RS01225	COG3161	chorismate lyase activity
JLF40_RS01230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JLF40_RS01240	COG3714	YhhN family
JLF40_RS01250	COG3776	membrane
JLF40_RS01255	COG0742	ribosomal rna small subunit methyltransferase
JLF40_RS01260	COG0552	protein localization to endoplasmic reticulum
JLF40_RS01265	COG2884	Cell division ATP-binding protein ftsE
JLF40_RS01270	COG2177	Part of the ABC transporter FtsEX involved in
JLF40_RS01275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JLF40_RS01280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JLF40_RS01295	COG0683	leucine binding
JLF40_RS01310	COG0411	ABC transporter
JLF40_RS01340	COG0584	glycerophosphoryl diester phosphodiesterase
JLF40_RS01350	COG0405	Gamma-glutamyltransferase
JLF40_RS01355	COG1247	-acetyltransferase
JLF40_RS01360	COG0673	inositol 2-dehydrogenase activity
JLF40_RS01365	COG1741	Belongs to the pirin family
JLF40_RS01370	COG1609	Transcriptional regulator
JLF40_RS01375	COG3265	gluconokinase activity
JLF40_RS01380	COG2610	gluconate transmembrane transporter activity
JLF40_RS01385	COG2937	Belongs to the GPAT DAPAT family
JLF40_RS01390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JLF40_RS01395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JLF40_RS01400	COG0534	Mate efflux family protein
JLF40_RS01405	COG3237	CsbD-like
JLF40_RS01410	COG0735	belongs to the Fur family
JLF40_RS01425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JLF40_RS01435	COG0604	alcohol dehydrogenase
JLF40_RS01440	COG0305	Participates in initiation and elongation during chromosome replication
JLF40_RS01455	COG2197	response regulator
JLF40_RS01475	COG3772	lysozyme
JLF40_RS01490	COG1448	Aminotransferase
JLF40_RS01495	COG3700	Belongs to the class B bacterial acid phosphatase family
JLF40_RS01505	COG2315	Protein conserved in bacteria
JLF40_RS01515	COG0629	single-stranded DNA binding
JLF40_RS01525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JLF40_RS01535	COG0789	Transcriptional regulator
JLF40_RS01545	COG2252	PERMEase
JLF40_RS01550	COG0025	NhaP-type Na H and K H
JLF40_RS01555	COG0583	DNA-binding transcription factor activity
JLF40_RS01560	COG1380	Effector of murein hydrolase LrgA
JLF40_RS01565	COG1346	cytolysis
JLF40_RS01570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JLF40_RS01575	COG3162	membrane
JLF40_RS01580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JLF40_RS01585	COG1301	dicarboxylic acid transport
JLF40_RS01590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JLF40_RS01620	COG0191	fructose-bisphosphate aldolase activity
JLF40_RS01635	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS01640	COG1129	ABC transporter
JLF40_RS01655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JLF40_RS01660	COG0456	acetyltransferase
JLF40_RS01665	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
JLF40_RS01670	COG3454	Phosphonate metabolism
JLF40_RS01675	COG4778	phosphonate C-P lyase system protein PhnL
JLF40_RS01680	COG4107	phosphonate C-P lyase system protein PhnK
JLF40_RS01685	COG3627	carbon phosphorus lyase activity
JLF40_RS01690	COG3626	phosphonate metabolism
JLF40_RS01695	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
JLF40_RS01700	COG3624	Phosphonate C-P lyase system protein PhnG
JLF40_RS01705	COG2188	Transcriptional regulator
JLF40_RS01710	COG3639	organic phosphonate transmembrane transporter activity
JLF40_RS01715	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JLF40_RS01725	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JLF40_RS01730	COG2824	Alkylphosphonate utilization operon protein PhnA
JLF40_RS01735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JLF40_RS01755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JLF40_RS01785	COG3328	transposase activity
JLF40_RS01795	COG2026	Addiction module toxin, RelE StbE family
JLF40_RS01800	COG3077	Addiction module antitoxin, RelB DinJ family
JLF40_RS01815	COG2801	Transposase and inactivated derivatives
JLF40_RS01825	COG2801	Transposase and inactivated derivatives
JLF40_RS01855	COG1309	transcriptional regulator
JLF40_RS01870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JLF40_RS01875	COG1027	Aspartate ammonia-lyase
JLF40_RS01880	COG3030	protein affecting phage T7 exclusion by the F plasmid
JLF40_RS01885	COG0531	amino acid
JLF40_RS01895	COG0459	protein refolding
JLF40_RS01905	COG1509	lysine 2,3-aminomutase activity
JLF40_RS01910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JLF40_RS01915	COG5510	response to toxic substance
JLF40_RS01945	COG0583	DNA-binding transcription factor activity
JLF40_RS01955	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JLF40_RS01960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JLF40_RS01965	COG1053	succinate dehydrogenase
JLF40_RS01970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JLF40_RS01975	COG1511	domain protein
JLF40_RS01975	COG3264	Mechanosensitive ion channel
JLF40_RS01990	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JLF40_RS02010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JLF40_RS02015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JLF40_RS02015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JLF40_RS02020	COG0802	atpase or kinase
JLF40_RS02030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JLF40_RS02035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JLF40_RS02040	COG1923	regulation of RNA biosynthetic process
JLF40_RS02045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JLF40_RS02050	COG0330	HflC and HflK could
JLF40_RS02055	COG0330	HflC and HflK could
JLF40_RS02060	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JLF40_RS02065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JLF40_RS02070	COG1959	2 iron, 2 sulfur cluster binding
JLF40_RS02075	COG0557	exoribonuclease II activity
JLF40_RS02080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JLF40_RS02085	COG0477	Major facilitator Superfamily
JLF40_RS02090	COG1960	acyl-CoA dehydrogenase activity
JLF40_RS02095	COG0840	transmembrane signaling receptor activity
JLF40_RS02105	COG3650	response to hydrogen peroxide
JLF40_RS02110	COG1073	alpha beta
JLF40_RS02125	COG2965	DNA replication, synthesis of RNA primer
JLF40_RS02130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JLF40_RS02135	COG0359	binds to the 23S rRNA
JLF40_RS02140	COG3061	Opacity-associated protein A
JLF40_RS02145	COG0545	Peptidyl-prolyl cis-trans isomerase
JLF40_RS02150	COG1113	amino acid transport
JLF40_RS02160	COG0840	transmembrane signaling receptor activity
JLF40_RS02165	COG0697	spore germination
JLF40_RS02175	COG2207	Transcriptional regulator
JLF40_RS02185	COG0702	epimerase
JLF40_RS02190	COG1733	regulation of RNA biosynthetic process
JLF40_RS02200	COG1218	3'(2'),5'-bisphosphate nucleotidase
JLF40_RS02205	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JLF40_RS02215	COG1253	flavin adenine dinucleotide binding
JLF40_RS02230	COG3423	Transcriptional regulator
JLF40_RS02245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS02260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JLF40_RS02265	COG0729	surface antigen
JLF40_RS02270	COG2911	Protein conserved in bacteria
JLF40_RS02275	COG2105	PFAM AIG2 family protein
JLF40_RS02295	COG1879	ABC-type sugar transport system periplasmic component
JLF40_RS02300	COG1129	ABC transporter
JLF40_RS02305	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS02310	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS02320	COG0583	DNA-binding transcription factor activity
JLF40_RS02330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JLF40_RS02335	COG3028	Belongs to the UPF0307 family
JLF40_RS02340	COG0312	modulator of DNA gyrase
JLF40_RS02375	COG3964	amidohydrolase
JLF40_RS02395	COG3711	transcriptional antiterminator
JLF40_RS02395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS02400	COG3077	Addiction module antitoxin, RelB DinJ family
JLF40_RS02405	COG2026	Addiction module toxin, RelE StbE family
JLF40_RS02410	COG0602	queuosine metabolic process
JLF40_RS02420	COG0366	Alpha amylase catalytic
JLF40_RS02425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS02425	COG1263	PTS System
JLF40_RS02430	COG1609	Transcriptional regulator
JLF40_RS02440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JLF40_RS02445	COG0251	oxidation-reduction process
JLF40_RS02455	COG0540	Belongs to the ATCase OTCase family
JLF40_RS02470	COG1438	arginine binding
JLF40_RS02475	COG1288	antiporter activity
JLF40_RS02490	COG2235	arginine
JLF40_RS02495	COG2731	YhcH YjgK YiaL family protein
JLF40_RS02510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JLF40_RS02555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JLF40_RS02635	COG4191	Histidine kinase
JLF40_RS02645	COG0346	lactoylglutathione lyase activity
JLF40_RS02650	COG0740	serine-type endopeptidase activity
JLF40_RS02685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JLF40_RS02695	COG1136	(ABC) transporter
JLF40_RS02730	COG2850	peptidyl-arginine hydroxylation
JLF40_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JLF40_RS02740	COG5457	Domain of unknown function (DUF1127)
JLF40_RS02755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JLF40_RS02760	COG0583	DNA-binding transcription factor activity
JLF40_RS02765	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS02775	COG0640	Transcriptional regulator
JLF40_RS02795	COG2733	membrane
JLF40_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS02840	COG0523	cobalamin synthesis protein
JLF40_RS02845	COG2879	small protein
JLF40_RS02850	COG1966	Carbon starvation protein
JLF40_RS02860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JLF40_RS02865	COG2368	4-hydroxyphenylacetate
JLF40_RS02885	COG3971	2-oxopent-4-enoate hydratase activity
JLF40_RS02895	COG3384	dioxygenase
JLF40_RS02900	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS02905	COG0179	Fumarylacetoacetate (FAA) hydrolase
JLF40_RS02910	COG1846	Transcriptional regulator
JLF40_RS02915	COG0840	transmembrane signaling receptor activity
JLF40_RS02935	COG1484	DNA-dependent DNA replication
JLF40_RS02945	COG1764	response to oxidative stress
JLF40_RS02950	COG1846	Transcriptional regulator
JLF40_RS02955	COG1309	transcriptional regulator
JLF40_RS02960	COG3610	response to peptide
JLF40_RS02965	COG2966	Psort location CytoplasmicMembrane, score
JLF40_RS02970	COG2197	response regulator
JLF40_RS02975	COG2197	response regulator
JLF40_RS02980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JLF40_RS02985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS02990	COG4114	ferric iron reductase
JLF40_RS03020	COG2813	Specifically methylates the guanine in position
JLF40_RS03025	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
JLF40_RS03030	COG0456	acetyltransferase
JLF40_RS03035	COG1011	Hydrolase
JLF40_RS03040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JLF40_RS03045	COG2823	Periplasmic or secreted lipoprotein
JLF40_RS03050	COG5487	UPF0391 membrane protein
JLF40_RS03055	COG4667	esterase of the alpha-beta hydrolase superfamily
JLF40_RS03060	COG0084	hydrolase, TatD family'
JLF40_RS03065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JLF40_RS03070	COG1328	CTP reductase activity
JLF40_RS03080	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JLF40_RS03090	COG0813	purine-nucleoside phosphorylase activity
JLF40_RS03100	COG3726	membrane protein affecting hemolysin expression
JLF40_RS03105	COG0560	Phosphoserine phosphatase
JLF40_RS03110	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JLF40_RS03130	COG0488	(ABC) transporter
JLF40_RS03135	COG0741	lytic transglycosylase activity
JLF40_RS03140	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JLF40_RS03145	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JLF40_RS03150	COG0406	alpha-ribazole phosphatase activity
JLF40_RS03155	COG2207	Transcriptional regulator
JLF40_RS03155	COG3708	Transcriptional regulator
JLF40_RS03160	COG3045	CreA protein
JLF40_RS03165	COG0745	RESPONSE REGULATOR receiver
JLF40_RS03170	COG2205	protein histidine kinase activity
JLF40_RS03175	COG4452	Inner membrane protein CreD
JLF40_RS03180	COG0745	RESPONSE REGULATOR receiver
JLF40_RS03190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JLF40_RS03200	COG0527	aspartate kinase activity
JLF40_RS03200	COG0460	homoserine dehydrogenase
JLF40_RS03210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JLF40_RS03220	COG3022	response to hydroperoxide
JLF40_RS03225	COG1115	amino acid carrier protein
JLF40_RS03235	COG0521	Mo-molybdopterin cofactor biosynthetic process
JLF40_RS03240	COG0477	Major facilitator Superfamily
JLF40_RS03245	COG1584	GPR1 FUN34 yaaH family protein
JLF40_RS03260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JLF40_RS03265	COG0583	DNA-binding transcription factor activity
JLF40_RS03270	COG0268	Binds directly to 16S ribosomal RNA
JLF40_RS03275	COG0196	riboflavin kinase activity
JLF40_RS03290	COG1047	Peptidyl-prolyl cis-trans
JLF40_RS03300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JLF40_RS03305	COG0505	Belongs to the CarA family
JLF40_RS03320	COG2249	NAD(P)H dehydrogenase (quinone) activity
JLF40_RS03325	COG0475	glutathione-regulated potassium exporter activity
JLF40_RS03325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JLF40_RS03335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JLF40_RS03340	COG2967	ApaG domain
JLF40_RS03350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JLF40_RS03355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JLF40_RS03360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JLF40_RS03365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JLF40_RS03370	COG0564	pseudouridine synthase activity
JLF40_RS03375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JLF40_RS03380	COG0417	DNA replication proofreading
JLF40_RS03385	COG0235	Class ii aldolase
JLF40_RS03390	COG2160	L-arabinose isomerase activity
JLF40_RS03395	COG1069	ribulokinase activity
JLF40_RS03405	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS03415	COG1178	ABC-type Fe3 transport system permease component
JLF40_RS03435	COG2814	Major facilitator Superfamily
JLF40_RS03445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JLF40_RS03465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JLF40_RS03480	COG0028	Belongs to the TPP enzyme family
JLF40_RS03485	COG0440	acetolactate synthase activity
JLF40_RS03490	COG1609	Transcriptional regulator
JLF40_RS03495	COG2001	Belongs to the MraZ family
JLF40_RS03510	COG0768	penicillin binding
JLF40_RS03515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JLF40_RS03520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JLF40_RS03525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JLF40_RS03535	COG0772	Belongs to the SEDS family
JLF40_RS03550	COG1181	Belongs to the D-alanine--D-alanine ligase family
JLF40_RS03560	COG0849	cell division
JLF40_RS03565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JLF40_RS03570	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JLF40_RS03580	COG0653	protein targeting
JLF40_RS03585	COG0494	nUDIX hydrolase
JLF40_RS03590	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JLF40_RS03595	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JLF40_RS03605	COG0516	GMP reductase activity
JLF40_RS03615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JLF40_RS03620	COG4969	Belongs to the N-Me-Phe pilin family
JLF40_RS03675	COG3023	N-Acetylmuramoyl-L-alanine amidase
JLF40_RS03680	COG3725	Membrane protein required for beta-lactamase induction
JLF40_RS03685	COG3940	Belongs to the glycosyl hydrolase 43 family
JLF40_RS03690	COG2211	Major facilitator Superfamily
JLF40_RS03695	COG1113	amino acid transport
JLF40_RS03705	COG2186	Transcriptional regulator
JLF40_RS03710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JLF40_RS03715	COG0508	dehydrogenase complex catalyzes the overall conversion of
JLF40_RS03720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JLF40_RS03730	COG3064	Membrane
JLF40_RS03735	COG1049	propionate catabolic process, 2-methylcitrate cycle
JLF40_RS03750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JLF40_RS03765	COG4993	Dehydrogenase
JLF40_RS03775	COG0288	reversible hydration of carbon dioxide
JLF40_RS03780	COG1131	(ABC) transporter
JLF40_RS03785	COG0842	Transport permease protein
JLF40_RS03790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS03795	COG0726	polysaccharide deacetylase
JLF40_RS03800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JLF40_RS03805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JLF40_RS03810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JLF40_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JLF40_RS03820	COG0617	tRNA 3'-terminal CCA addition
JLF40_RS03825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JLF40_RS03835	COG1489	DNA binding
JLF40_RS03840	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JLF40_RS03845	COG1643	Atp-dependent helicase
JLF40_RS03850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JLF40_RS03855	COG4774	siderophore transport
JLF40_RS03860	COG1120	ATPase activity
JLF40_RS03865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JLF40_RS03870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS03875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JLF40_RS03885	COG0316	Belongs to the HesB IscA family
JLF40_RS03890	COG2860	membrane
JLF40_RS03900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JLF40_RS03905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JLF40_RS03915	COG3835	regulator
JLF40_RS03945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JLF40_RS03960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JLF40_RS03970	COG0575	Belongs to the CDS family
JLF40_RS03975	COG0750	zinc metalloprotease
JLF40_RS03980	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JLF40_RS03990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JLF40_RS03995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JLF40_RS04000	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JLF40_RS04005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JLF40_RS04010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JLF40_RS04025	COG1982	Orn Lys Arg decarboxylase major
JLF40_RS04030	COG0346	lactoylglutathione lyase activity
JLF40_RS04035	COG0037	tRNA processing
JLF40_RS04040	COG4568	rho-dependent transcription termination
JLF40_RS04055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JLF40_RS04060	COG3015	lipoprotein NlpE involved in copper resistance
JLF40_RS04070	COG1720	tRNA m6t6A37 methyltransferase activity
JLF40_RS04080	COG1464	Belongs to the NlpA lipoprotein family
JLF40_RS04085	COG2011	ABC-type metal ion transport system permease component
JLF40_RS04095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JLF40_RS04135	COG0583	DNA-binding transcription factor activity
JLF40_RS04140	COG2814	Major facilitator Superfamily
JLF40_RS04145	COG3021	interspecies interaction between organisms
JLF40_RS04150	COG2226	methyltransferase
JLF40_RS04155	COG0741	lytic transglycosylase activity
JLF40_RS04155	COG1388	LysM domain
JLF40_RS04160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JLF40_RS04165	COG2226	methyltransferase
JLF40_RS04190	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS04195	COG4608	Belongs to the ABC transporter superfamily
JLF40_RS04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS04220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JLF40_RS04225	COG1960	acyl-CoA dehydrogenase activity
JLF40_RS04235	COG0121	glutamine amidotransferase
JLF40_RS04240	COG3034	peptidoglycan biosynthetic process
JLF40_RS04255	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JLF40_RS04260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JLF40_RS04275	COG2991	Protein conserved in bacteria
JLF40_RS04280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JLF40_RS04285	COG2195	Cleaves the N-terminal amino acid of tripeptides
JLF40_RS04295	COG1073	alpha beta
JLF40_RS04305	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JLF40_RS04310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JLF40_RS04315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JLF40_RS04325	COG0582	viral genome integration into host DNA
JLF40_RS04340	COG3039	Transposase
JLF40_RS04350	COG3561	AntA/AntB antirepressor
JLF40_RS04415	COG5001	Diguanylate cyclase
JLF40_RS04415	COG3300	MHYT domain
JLF40_RS04445	COG0628	permease
JLF40_RS04455	COG0833	amino acid
JLF40_RS04460	COG2040	homocysteine
JLF40_RS04465	COG4521	taurine ABC transporter
JLF40_RS04470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JLF40_RS04475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JLF40_RS04480	COG2175	clavaminate synthase activity
JLF40_RS04490	COG0113	porphobilinogen synthase activity
JLF40_RS04505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JLF40_RS04515	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
JLF40_RS04535	COG1181	Belongs to the D-alanine--D-alanine ligase family
JLF40_RS04555	COG1785	Belongs to the alkaline phosphatase family
JLF40_RS04565	COG3706	GGDEF domain
JLF40_RS04570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JLF40_RS04575	COG1671	Belongs to the UPF0178 family
JLF40_RS04580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JLF40_RS04590	COG4126	flavin adenine dinucleotide binding
JLF40_RS04595	COG3123	guanosine phosphorylase activity
JLF40_RS04605	COG1940	carbohydrate kinase activity
JLF40_RS04610	COG0419	ATPase involved in DNA repair
JLF40_RS04615	COG0420	3'-5' exonuclease activity
JLF40_RS04625	COG5002	protein histidine kinase activity
JLF40_RS04640	COG0366	Alpha amylase catalytic
JLF40_RS04655	COG0450	alkyl hydroperoxide reductase
JLF40_RS04660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JLF40_RS04675	COG1862	Preprotein translocase
JLF40_RS04680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JLF40_RS04685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JLF40_RS04705	COG4238	major outer membrane lipoprotein
JLF40_RS04710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JLF40_RS04715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JLF40_RS04715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JLF40_RS04720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JLF40_RS04725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JLF40_RS04730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JLF40_RS04735	COG0667	Aldo Keto reductase
JLF40_RS04740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JLF40_RS04745	COG0142	geranyltranstransferase activity
JLF40_RS04760	COG0693	protein deglycase activity
JLF40_RS04765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JLF40_RS04775	COG2814	Major facilitator Superfamily
JLF40_RS04780	COG0109	protoheme IX farnesyltransferase activity
JLF40_RS04785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JLF40_RS04790	COG1845	cytochrome c oxidase, subunit III
JLF40_RS04795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JLF40_RS04800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JLF40_RS04805	COG2223	nitrite transmembrane transporter activity
JLF40_RS04810	COG3056	Lipoprotein
JLF40_RS04815	COG0271	Belongs to the BolA IbaG family
JLF40_RS04820	COG0544	peptidyl-prolyl cis-trans isomerase activity
JLF40_RS04830	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JLF40_RS04835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JLF40_RS04840	COG0776	regulation of translation
JLF40_RS04845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JLF40_RS04850	COG1555	photosystem II stabilization
JLF40_RS04855	COG0824	Thioesterase
JLF40_RS04860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JLF40_RS04865	COG4533	DNA binding
JLF40_RS04870	COG0561	phosphatase activity
JLF40_RS04880	COG1522	sequence-specific DNA binding
JLF40_RS04885	COG1132	(ABC) transporter
JLF40_RS04890	COG1132	(ABC) transporter
JLF40_RS04895	COG0347	Belongs to the P(II) protein family
JLF40_RS04900	COG0004	ammonium transporteR
JLF40_RS04905	COG1946	Acyl-CoA thioesterase
JLF40_RS04910	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JLF40_RS04915	COG3695	enzyme binding
JLF40_RS04935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JLF40_RS04940	COG2364	Membrane
JLF40_RS04945	COG1609	Transcriptional regulator
JLF40_RS04965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JLF40_RS04975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JLF40_RS04995	COG0110	maltose O-acetyltransferase activity
JLF40_RS05010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS05015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS05020	COG1309	transcriptional regulator
JLF40_RS05025	COG1196	nuclear chromosome segregation
JLF40_RS05025	COG3264	Mechanosensitive ion channel
JLF40_RS05035	COG3923	Primosomal replication protein n
JLF40_RS05040	COG2832	Protein of unknown function (DUF454)
JLF40_RS05045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JLF40_RS05055	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JLF40_RS05060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JLF40_RS05065	COG0326	Molecular chaperone. Has ATPase activity
JLF40_RS05075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JLF40_RS05080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JLF40_RS05085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JLF40_RS05085	COG4651	solute:proton antiporter activity
JLF40_RS05090	COG2223	nitrite transmembrane transporter activity
JLF40_RS05100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JLF40_RS05105	COG3735	TraB family
JLF40_RS05110	COG2217	Heavy metal translocating P-type atpase
JLF40_RS05120	COG1585	Membrane protein implicated in regulation of membrane protease activity
JLF40_RS05125	COG0330	HflC and HflK could
JLF40_RS05135	COG4619	ABC transporter
JLF40_RS05140	COG0390	transport system, permease component
JLF40_RS05145	COG3118	belongs to the thioredoxin family
JLF40_RS05150	COG0300	oxidoreductase activity
JLF40_RS05155	COG2755	lipolytic protein G-D-S-L family
JLF40_RS05160	COG4181	ATPase activity
JLF40_RS05165	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JLF40_RS05215	COG3344	reverse transcriptase
JLF40_RS05230	COG0789	Transcriptional regulator
JLF40_RS05270	COG0183	Belongs to the thiolase family
JLF40_RS05280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JLF40_RS05335	COG0625	glutathione transferase activity
JLF40_RS05340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JLF40_RS05350	COG0583	DNA-binding transcription factor activity
JLF40_RS05360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JLF40_RS05390	COG1846	Transcriptional regulator
JLF40_RS05395	COG0583	DNA-binding transcription factor activity
JLF40_RS05405	COG2948	multi-organism process
JLF40_RS05455	COG1902	pentaerythritol trinitrate reductase activity
JLF40_RS05460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JLF40_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS05470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JLF40_RS05500	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JLF40_RS05545	COG3328	transposase activity
JLF40_RS05565	COG0642	Histidine kinase
JLF40_RS05575	COG2194	sulfuric ester hydrolase activity
JLF40_RS05585	COG2205	protein histidine kinase activity
JLF40_RS05620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JLF40_RS05625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JLF40_RS05640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JLF40_RS05645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JLF40_RS05655	COG1988	membrane-bound metal-dependent
JLF40_RS05660	COG1609	Transcriptional regulator
JLF40_RS05665	COG1263	PTS System
JLF40_RS05665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS05665	COG2190	(PTS) system
JLF40_RS05670	COG2501	S4 domain
JLF40_RS05760	COG1113	amino acid transport
JLF40_RS05765	COG0668	transmembrane transport
JLF40_RS05770	COG0477	Major facilitator Superfamily
JLF40_RS05780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JLF40_RS05790	COG3121	Chaperone
JLF40_RS05800	COG3539	Fimbrial protein
JLF40_RS05810	COG3188	usher protein
JLF40_RS05815	COG3539	Fimbrial protein
JLF40_RS05840	COG2831	hemolysin activation secretion protein
JLF40_RS05845	COG3210	domain, Protein
JLF40_RS05850	COG0778	Nitroreductase
JLF40_RS05855	COG2315	Protein conserved in bacteria
JLF40_RS05895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JLF40_RS05905	COG2207	Transcriptional regulator
JLF40_RS05920	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS05940	COG5499	transcription regulator containing HTH domain
JLF40_RS05955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JLF40_RS05965	COG0583	DNA-binding transcription factor activity
JLF40_RS06015	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS06020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS06025	COG0601	transmembrane transport
JLF40_RS06045	COG4221	oxidoreductase activity
JLF40_RS06060	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JLF40_RS06080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JLF40_RS06085	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
JLF40_RS06100	COG4771	TonB-dependent receptor
JLF40_RS06105	COG2382	esterase
JLF40_RS06110	COG3251	PFAM MbtH domain protein
JLF40_RS06115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JLF40_RS06115	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JLF40_RS06120	COG1120	ATPase activity
JLF40_RS06125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS06130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS06140	COG4592	Periplasmic binding protein
JLF40_RS06145	COG1169	isochorismate synthase
JLF40_RS06150	COG1021	2,3-dihydroxybenzoate-AMP ligase
JLF40_RS06155	COG1535	isochorismatase
JLF40_RS06155	COG3433	isochorismatase activity
JLF40_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS06165	COG2050	protein possibly involved in aromatic compounds catabolism
JLF40_RS06170	COG1966	Carbon starvation protein
JLF40_RS06175	COG2879	small protein
JLF40_RS06195	COG0371	Dehydrogenase
JLF40_RS06200	COG1129	ABC transporter
JLF40_RS06205	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS06220	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JLF40_RS06225	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JLF40_RS06240	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
JLF40_RS06245	COG0235	Class ii aldolase
JLF40_RS06250	COG0436	Aminotransferase
JLF40_RS06255	COG1475	DNA binding
JLF40_RS06260	COG3969	phosphoadenosine phosphosulfate
JLF40_RS06265	COG0583	DNA-binding transcription factor activity
JLF40_RS06285	COG1063	alcohol dehydrogenase
JLF40_RS06290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JLF40_RS06295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JLF40_RS06300	COG3719	Belongs to the RNase T2 family
JLF40_RS06305	COG3069	C4-dicarboxylate transmembrane transporter activity
JLF40_RS06320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JLF40_RS06325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JLF40_RS06330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JLF40_RS06335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JLF40_RS06340	COG0583	DNA-binding transcription factor activity
JLF40_RS06345	COG0321	lipoyl(octanoyl) transferase activity
JLF40_RS06350	COG2921	Belongs to the UPF0250 family
JLF40_RS06355	COG1686	Belongs to the peptidase S11 family
JLF40_RS06360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JLF40_RS06365	COG0772	Belongs to the SEDS family
JLF40_RS06370	COG0768	penicillin binding
JLF40_RS06380	COG0799	negative regulation of ribosome biogenesis
JLF40_RS06390	COG1466	dna polymerase III delta subunit
JLF40_RS06405	COG2888	peptidyl-tyrosine sulfation
JLF40_RS06410	COG1957	nucleoside hydrolase
JLF40_RS06415	COG1126	abc transporter atp-binding protein
JLF40_RS06420	COG0765	amino acid transport
JLF40_RS06425	COG0765	amino acid transport
JLF40_RS06435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JLF40_RS06440	COG4535	Mg2 and Co2 transporter CorC
JLF40_RS06445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JLF40_RS06450	COG1702	phosphate starvation-inducible protein PhoH
JLF40_RS06455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JLF40_RS06460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JLF40_RS06500	COG0367	asparagine synthase
JLF40_RS06505	COG0647	UMP catabolic process
JLF40_RS06510	COG1940	carbohydrate kinase activity
JLF40_RS06510	COG1846	Transcriptional regulator
JLF40_RS06515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JLF40_RS06525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS06525	COG2190	(PTS) system
JLF40_RS06525	COG1263	PTS System
JLF40_RS06530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JLF40_RS06545	COG0735	belongs to the Fur family
JLF40_RS06560	COG0596	Alpha beta hydrolase
JLF40_RS06565	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JLF40_RS06570	COG0033	Phosphoglucomutase
JLF40_RS06575	COG0531	amino acid
JLF40_RS06580	COG1982	Orn Lys Arg decarboxylase major
JLF40_RS06590	COG0745	RESPONSE REGULATOR receiver
JLF40_RS06595	COG2205	protein histidine kinase activity
JLF40_RS06600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JLF40_RS06605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JLF40_RS06610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JLF40_RS06625	COG0415	Belongs to the DNA photolyase family
JLF40_RS06630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JLF40_RS06635	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JLF40_RS06640	COG1984	allophanate hydrolase subunit 2
JLF40_RS06650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JLF40_RS06655	COG0372	Belongs to the citrate synthase family
JLF40_RS06660	COG2009	succinate dehydrogenase
JLF40_RS06665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JLF40_RS06670	COG1053	succinate dehydrogenase
JLF40_RS06675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JLF40_RS06680	COG0567	Dehydrogenase, E1 component
JLF40_RS06685	COG0508	dehydrogenase complex catalyzes the overall conversion of
JLF40_RS06690	COG0045	succinate-CoA ligase (ADP-forming) activity
JLF40_RS06695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JLF40_RS06700	COG1271	oxidase subunit
JLF40_RS06705	COG1294	oxidase, subunit
JLF40_RS06710	COG4890	Cyd operon protein YbgT
JLF40_RS06715	COG3790	cyd operon protein YbgE
JLF40_RS06720	COG0824	Thioesterase
JLF40_RS06725	COG0811	peptide transport
JLF40_RS06730	COG0848	biopolymer transport protein
JLF40_RS06735	COG3064	Membrane
JLF40_RS06745	COG2885	chlorophyll binding
JLF40_RS06750	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JLF40_RS06780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JLF40_RS06785	COG3201	nicotinamide mononucleotide transporter
JLF40_RS06790	COG1230	cation diffusion facilitator family transporter
JLF40_RS06800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JLF40_RS06810	COG2017	converts alpha-aldose to the beta-anomer
JLF40_RS06815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JLF40_RS06820	COG1085	galactose-1-phosphate uridylyltransferase
JLF40_RS06825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JLF40_RS06830	COG1119	ATPase activity
JLF40_RS06835	COG3585	molybdate ion transport
JLF40_RS06835	COG2005	Transcriptional regulator
JLF40_RS06845	COG0725	ABC transporter, periplasmic molybdate-binding protein
JLF40_RS06850	COG4149	molybdate abc transporter
JLF40_RS06860	COG0561	phosphatase activity
JLF40_RS06865	COG2706	6-phosphogluconolactonase activity
JLF40_RS06870	COG4677	pectinesterase activity
JLF40_RS06880	COG0010	Belongs to the arginase family
JLF40_RS06890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JLF40_RS06895	COG2986	histidine ammonia-lyase
JLF40_RS06900	COG1881	PFAM PEBP family protein
JLF40_RS06905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JLF40_RS06910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JLF40_RS06915	COG0156	8-amino-7-oxononanoate synthase activity
JLF40_RS06920	COG2226	methyltransferase
JLF40_RS06925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JLF40_RS06930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JLF40_RS06950	COG0521	Mo-molybdopterin cofactor biosynthetic process
JLF40_RS06955	COG0315	cyclic pyranopterin monophosphate synthase activity
JLF40_RS06960	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JLF40_RS06965	COG0314	molybdopterin synthase activity
JLF40_RS06970	COG0670	Belongs to the BI1 family
JLF40_RS06975	COG0392	lysyltransferase activity
JLF40_RS06980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JLF40_RS06985	COG3568	Endonuclease Exonuclease Phosphatase
JLF40_RS06995	COG0842	Transport permease protein
JLF40_RS07000	COG0842	Transport permease protein
JLF40_RS07005	COG1131	(ABC) transporter
JLF40_RS07010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS07015	COG1309	transcriptional regulator
JLF40_RS07020	COG0513	Belongs to the DEAD box helicase family
JLF40_RS07025	COG1199	ATP-dependent helicase activity
JLF40_RS07055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JLF40_RS07065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JLF40_RS07075	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JLF40_RS07080	COG0668	transmembrane transport
JLF40_RS07085	COG1126	abc transporter atp-binding protein
JLF40_RS07090	COG0765	amino acid transport
JLF40_RS07095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS07100	COG0783	Belongs to the Dps family
JLF40_RS07110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
JLF40_RS07115	COG2194	sulfuric ester hydrolase activity
JLF40_RS07125	COG1321	iron dependent repressor
JLF40_RS07130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JLF40_RS07135	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS07140	COG2814	Major facilitator Superfamily
JLF40_RS07150	COG0667	Aldo Keto reductase
JLF40_RS07155	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS07160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS07165	COG2188	Transcriptional regulator
JLF40_RS07170	COG1376	ErfK ybiS ycfS ynhG family protein
JLF40_RS07180	COG3039	Transposase
JLF40_RS07230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS07235	COG0488	(ABC) transporter
JLF40_RS07245	COG2271	Major facilitator Superfamily
JLF40_RS07250	COG1609	Transcriptional regulator
JLF40_RS07260	COG0561	phosphatase activity
JLF40_RS07265	COG1882	Formate acetyltransferase
JLF40_RS07270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JLF40_RS07275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JLF40_RS07280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JLF40_RS07290	COG1446	asparaginase
JLF40_RS07340	COG2133	pyrroloquinoline quinone binding
JLF40_RS07345	COG0625	glutathione transferase activity
JLF40_RS07350	COG1686	Belongs to the peptidase S11 family
JLF40_RS07355	COG1349	DNA-binding transcription factor activity
JLF40_RS07360	COG0671	phosphoesterase, PA-phosphatase related
JLF40_RS07370	COG2814	Major facilitator Superfamily
JLF40_RS07375	COG0561	phosphatase activity
JLF40_RS07380	COG0738	Major facilitator superfamily
JLF40_RS07385	COG3226	Transcriptional regulator
JLF40_RS07395	COG1393	Belongs to the ArsC family
JLF40_RS07400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JLF40_RS07405	COG0640	Transcriptional regulator
JLF40_RS07410	COG2985	domain, Protein
JLF40_RS07410	COG0569	domain protein
JLF40_RS07425	COG0778	Nitroreductase
JLF40_RS07430	COG0189	ligase activity
JLF40_RS07440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JLF40_RS07445	COG3842	ATPase activity
JLF40_RS07450	COG1176	ABC-type spermidine putrescine transport system, permease component I
JLF40_RS07455	COG1177	transmembrane transport
JLF40_RS07465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JLF40_RS07470	COG0745	RESPONSE REGULATOR receiver
JLF40_RS07475	COG5002	protein histidine kinase activity
JLF40_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS07485	COG4160	amino acid transport
JLF40_RS07490	COG4215	(ABC) transporter
JLF40_RS07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS07500	COG1126	abc transporter atp-binding protein
JLF40_RS07510	COG0393	Putative heavy-metal-binding
JLF40_RS07515	COG3023	N-Acetylmuramoyl-L-alanine amidase
JLF40_RS07520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JLF40_RS07530	COG3409	Peptidoglycan-binding domain 1 protein
JLF40_RS07530	COG3267	Type II secretory pathway component ExeA
JLF40_RS07535	COG3031	protein transport across the cell outer membrane
JLF40_RS07540	COG1450	Type ii and iii secretion system protein
JLF40_RS07545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JLF40_RS07550	COG1459	type II secretion system
JLF40_RS07555	COG2165	general secretion pathway protein
JLF40_RS07565	COG2165	general secretion pathway protein
JLF40_RS07590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JLF40_RS07610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JLF40_RS07615	COG0702	epimerase
JLF40_RS07620	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JLF40_RS07625	COG0028	Belongs to the TPP enzyme family
JLF40_RS07635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JLF40_RS07640	COG1151	hydroxylamine reductase activity
JLF40_RS07645	COG2431	L-lysine efflux transmembrane transporter activity
JLF40_RS07655	COG3593	DNA synthesis involved in DNA repair
JLF40_RS07660	COG2990	Protein conserved in bacteria
JLF40_RS07665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS07675	COG1278	Cold shock
JLF40_RS07680	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JLF40_RS07685	COG0542	response to heat
JLF40_RS07700	COG0737	Belongs to the 5'-nucleotidase family
JLF40_RS07710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JLF40_RS07715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JLF40_RS07720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JLF40_RS07725	COG4988	ABC transporter
JLF40_RS07730	COG0492	ferredoxin-NADP+ reductase activity
JLF40_RS07740	COG1178	ABC-type Fe3 transport system permease component
JLF40_RS07740	COG1674	ftsk spoiiie
JLF40_RS07745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JLF40_RS07750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JLF40_RS07755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JLF40_RS07760	COG0243	molybdopterin cofactor binding
JLF40_RS07770	COG3302	dmso reductase anchor subunit
JLF40_RS07775	COG0477	Major facilitator Superfamily
JLF40_RS07785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JLF40_RS07790	COG1882	Formate acetyltransferase
JLF40_RS07795	COG2116	formate transmembrane transporter activity
JLF40_RS07800	COG1944	ATP diphosphatase activity
JLF40_RS07805	COG2323	membrane
JLF40_RS07810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JLF40_RS07815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JLF40_RS07820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JLF40_RS07825	COG0539	negative regulation of cytoplasmic translation
JLF40_RS07830	COG0776	regulation of translation
JLF40_RS07835	COG2333	competence protein COMEC
JLF40_RS07835	COG0658	competence protein
JLF40_RS07850	COG3214	Protein conserved in bacteria
JLF40_RS07855	COG2835	tetraacyldisaccharide 4'-kinase activity
JLF40_RS07860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JLF40_RS07865	COG3173	Aminoglycoside phosphotransferase
JLF40_RS07870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JLF40_RS07875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JLF40_RS07885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JLF40_RS07890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JLF40_RS07895	COG2989	Protein conserved in bacteria
JLF40_RS07900	COG3108	Peptidase M15
JLF40_RS07905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JLF40_RS07910	COG1448	Aminotransferase
JLF40_RS07920	COG0017	Asparaginyl-tRNA synthetase
JLF40_RS07925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JLF40_RS07930	COG0308	aminopeptidase N
JLF40_RS07940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JLF40_RS07945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS07950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JLF40_RS07955	COG0431	NADPH-dependent FMN reductase
JLF40_RS07960	COG0167	dihydroorotate dehydrogenase activity
JLF40_RS07970	COG0633	Ferredoxin
JLF40_RS07970	COG3217	Mosc domain protein beta barrel domain protein
JLF40_RS07975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JLF40_RS07975	COG0116	Belongs to the methyltransferase superfamily
JLF40_RS07980	COG0488	(ABC) transporter
JLF40_RS07985	COG2995	paraquat-inducible protein a
JLF40_RS07990	COG3008	intermembrane lipid transfer
JLF40_RS07990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JLF40_RS07995	COG3009	Protein conserved in bacteria
JLF40_RS08000	COG3130	regulation of translation
JLF40_RS08010	COG1067	ATP-dependent peptidase activity
JLF40_RS08015	COG3120	sequence-specific DNA binding
JLF40_RS08025	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
JLF40_RS08030	COG3070	regulator of competence-specific genes
JLF40_RS08035	COG1289	transmembrane transporter activity
JLF40_RS08040	COG3304	Inner membrane component domain
JLF40_RS08045	COG0210	DNA helicase
JLF40_RS08050	COG1803	Methylglyoxal synthase
JLF40_RS08055	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JLF40_RS08060	COG1832	CoA-binding protein
JLF40_RS08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JLF40_RS08075	COG1881	PFAM PEBP family protein
JLF40_RS08085	COG1254	Belongs to the acylphosphatase family
JLF40_RS08090	COG2920	part of a sulfur-relay system
JLF40_RS08130	COG0670	Belongs to the BI1 family
JLF40_RS08165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JLF40_RS08170	COG1696	Membrane protein involved in D-alanine export
JLF40_RS08195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JLF40_RS08200	COG3648	Uricase
JLF40_RS08200	COG3195	allantoin biosynthetic process
JLF40_RS08205	COG2351	hydroxyisourate hydrolase activity
JLF40_RS08210	COG0402	S-adenosylhomocysteine deaminase activity
JLF40_RS08215	COG1953	Uracil, thiamine, allantoin
JLF40_RS08270	COG0765	amino acid transport
JLF40_RS08275	COG1126	abc transporter atp-binding protein
JLF40_RS08280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JLF40_RS08290	COG2239	Acts as a magnesium transporter
JLF40_RS08295	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS08305	COG1733	regulation of RNA biosynthetic process
JLF40_RS08330	COG0655	NAD(P)H dehydrogenase (quinone) activity
JLF40_RS08335	COG3729	General stress protein
JLF40_RS08355	COG2233	PERMEase
JLF40_RS08360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JLF40_RS08365	COG0778	Nitroreductase
JLF40_RS08370	COG2267	carboxylic ester hydrolase activity
JLF40_RS08375	COG0251	oxidation-reduction process
JLF40_RS08380	COG1335	isochorismatase
JLF40_RS08385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS08390	COG1309	transcriptional regulator
JLF40_RS08400	COG0506	proline dehydrogenase activity
JLF40_RS08400	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JLF40_RS08400	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JLF40_RS08405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JLF40_RS08415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JLF40_RS08425	COG2822	iron ion transport
JLF40_RS08435	COG1702	phosphate starvation-inducible protein PhoH
JLF40_RS08450	COG1335	isochorismatase
JLF40_RS08460	COG0583	DNA-binding transcription factor activity
JLF40_RS08470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JLF40_RS08475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JLF40_RS08480	COG3381	protein complex oligomerization
JLF40_RS08505	COG2197	response regulator
JLF40_RS08530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JLF40_RS08545	COG2943	transferase activity, transferring hexosyl groups
JLF40_RS08550	COG5645	(Lipo)protein
JLF40_RS08565	COG1560	Kdo2-lipid A biosynthetic process
JLF40_RS08570	COG1054	Belongs to the UPF0176 family
JLF40_RS08575	COG2353	YceI-like domain
JLF40_RS08580	COG3038	cytochrome b561
JLF40_RS08605	COG0418	dihydroorotase activity
JLF40_RS08615	COG0477	Major facilitator Superfamily
JLF40_RS08620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS08625	COG3132	Protein of unknown function, DUF480
JLF40_RS08630	COG0673	inositol 2-dehydrogenase activity
JLF40_RS08635	COG0728	peptidoglycan biosynthetic process
JLF40_RS08660	COG1558	bacterial-type flagellum-dependent cell motility
JLF40_RS08665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JLF40_RS08670	COG1749	Flagellar hook protein flgE
JLF40_RS08680	COG4786	Flagellar basal body rod
JLF40_RS08700	COG1256	bacterial-type flagellum assembly
JLF40_RS08705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JLF40_RS08710	COG2814	Major facilitator Superfamily
JLF40_RS08715	COG0583	DNA-binding transcription factor activity
JLF40_RS08720	COG1530	ribonuclease E activity
JLF40_RS08725	COG0564	pseudouridine synthase activity
JLF40_RS08730	COG0424	maF-like protein
JLF40_RS08740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JLF40_RS08745	COG0416	fatty acid biosynthetic process
JLF40_RS08750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JLF40_RS08765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JLF40_RS08770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JLF40_RS08775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JLF40_RS08780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JLF40_RS08785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JLF40_RS08790	COG0470	DNA polymerase III
JLF40_RS08795	COG0084	hydrolase, TatD family'
JLF40_RS08805	COG0537	adenosine 5'-monophosphoramidase activity
JLF40_RS08810	COG5633	Lipoprotein
JLF40_RS08815	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
JLF40_RS08830	COG3150	esterase
JLF40_RS08835	COG1252	NADH dehydrogenase
JLF40_RS08840	COG3134	Outer membrane lipoprotein
JLF40_RS08845	COG1309	transcriptional regulator
JLF40_RS08855	COG1388	LysM domain
JLF40_RS08855	COG1376	ErfK ybiS ycfS ynhG family protein
JLF40_RS08860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JLF40_RS08865	COG4763	Acyl-transferase
JLF40_RS08870	COG4591	ABC-type transport system involved in lipoprotein release permease component
JLF40_RS08875	COG1136	(ABC) transporter
JLF40_RS08880	COG4591	ABC-type transport system involved in lipoprotein release permease component
JLF40_RS08890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JLF40_RS08895	COG0840	transmembrane signaling receptor activity
JLF40_RS08900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JLF40_RS08935	COG2850	peptidyl-arginine hydroxylation
JLF40_RS08950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JLF40_RS08955	COG2915	High frequency lysogenization protein hflD homolog
JLF40_RS08975	COG0538	isocitrate dehydrogenase activity
JLF40_RS08995	COG2200	EAL domain
JLF40_RS09000	COG5001	Diguanylate cyclase
JLF40_RS09000	COG3706	GGDEF domain
JLF40_RS09000	COG2203	Gaf domain
JLF40_RS09000	COG4251	negative regulation of phosphorylation
JLF40_RS09005	COG2261	transglycosylase associated protein
JLF40_RS09015	COG2203	Gaf domain
JLF40_RS09015	COG2199	diguanylate cyclase activity
JLF40_RS09020	COG3042	response to heat
JLF40_RS09030	COG3189	MarR family transcriptional regulator
JLF40_RS09035	COG0504	CTP synthase activity
JLF40_RS09040	COG2807	transmembrane transport
JLF40_RS09045	COG2207	Transcriptional regulator
JLF40_RS09050	COG2707	UPF0756 membrane protein
JLF40_RS09060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JLF40_RS09065	COG0582	viral genome integration into host DNA
JLF40_RS09170	COG1403	HNH endonuclease
JLF40_RS09175	COG0484	heat shock protein binding
JLF40_RS09190	COG3179	chitinase
JLF40_RS09250	COG0616	signal peptide processing
JLF40_RS09290	COG4386	tail sheath protein
JLF40_RS09305	COG0741	lytic transglycosylase activity
JLF40_RS09365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS09405	COG2718	Belongs to the UPF0229 family
JLF40_RS09410	COG2766	serine protein kinase
JLF40_RS09415	COG3713	MltA-interacting MipA family protein
JLF40_RS09435	COG3139	Protein of unknown function (DUF1315)
JLF40_RS09440	COG1335	isochorismatase
JLF40_RS09445	COG0252	asparaginase activity
JLF40_RS09450	COG0616	signal peptide processing
JLF40_RS09455	COG0778	Nitroreductase
JLF40_RS09460	COG0709	Synthesizes selenophosphate from selenide and ATP
JLF40_RS09465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JLF40_RS09480	COG0494	nUDIX hydrolase
JLF40_RS09485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JLF40_RS09490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JLF40_RS09495	COG2897	thiosulfate sulfurtransferase activity
JLF40_RS09500	COG4136	ATPase activity
JLF40_RS09505	COG4135	transport system, permease component
JLF40_RS09510	COG4134	Bacterial extracellular solute-binding protein
JLF40_RS09520	COG0708	Exodeoxyribonuclease III
JLF40_RS09530	COG3138	arginine N-succinyltransferase
JLF40_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS09540	COG3724	N-succinylarginine dihydrolase activity
JLF40_RS09550	COG3678	ATP-independent chaperone mediated protein folding
JLF40_RS09560	COG0322	excinuclease ABC activity
JLF40_RS09565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JLF40_RS09570	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JLF40_RS09575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS09580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JLF40_RS09585	COG1447	Phosphotransferase system cellobiose-specific component IIA
JLF40_RS09590	COG2169	Transcriptional regulator
JLF40_RS09590	COG1917	Cupin 2, conserved barrel domain protein
JLF40_RS09595	COG1486	melibiose metabolic process
JLF40_RS09600	COG3394	polysaccharide catabolic process
JLF40_RS09605	COG0753	catalase activity
JLF40_RS09615	COG1823	symporter activity
JLF40_RS09620	COG1988	membrane-bound metal-dependent
JLF40_RS09625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JLF40_RS09635	COG3001	Fructosamine kinase
JLF40_RS09645	COG1105	Belongs to the carbohydrate kinase PfkB family
JLF40_RS09650	COG3137	Salt-induced outer membrane protein
JLF40_RS09665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JLF40_RS09675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JLF40_RS09690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JLF40_RS09695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JLF40_RS09695	COG0072	phenylalanine-tRNA ligase activity
JLF40_RS09700	COG0776	regulation of translation
JLF40_RS09710	COG0386	Belongs to the glutathione peroxidase family
JLF40_RS09720	COG0791	NLP P60 protein
JLF40_RS09730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JLF40_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS09740	COG2610	gluconate transmembrane transporter activity
JLF40_RS09750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JLF40_RS09755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JLF40_RS09760	COG0583	DNA-binding transcription factor activity
JLF40_RS09770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS09775	COG4558	Periplasmic binding protein
JLF40_RS09780	COG3720	iron ion transport
JLF40_RS09790	COG4256	Hemin uptake protein
JLF40_RS09795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JLF40_RS09800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JLF40_RS09805	COG0574	Belongs to the PEP-utilizing enzyme family
JLF40_RS09805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JLF40_RS09810	COG2211	Major facilitator Superfamily
JLF40_RS09815	COG1472	Belongs to the glycosyl hydrolase 3 family
JLF40_RS09825	COG0628	permease
JLF40_RS09830	COG0247	lactate metabolic process
JLF40_RS09830	COG0277	FAD linked oxidase domain protein
JLF40_RS09835	COG2050	protein possibly involved in aromatic compounds catabolism
JLF40_RS09845	COG3383	formate dehydrogenase (NAD+) activity
JLF40_RS09865	COG2200	EAL domain
JLF40_RS09870	COG0789	Transcriptional regulator
JLF40_RS09875	COG0316	Belongs to the HesB IscA family
JLF40_RS09880	COG0719	Fe-S assembly protein
JLF40_RS09885	COG0396	ATPase activity
JLF40_RS09890	COG0719	Fe-S assembly protein
JLF40_RS09895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JLF40_RS09900	COG2166	iron-sulfur cluster assembly
JLF40_RS09905	COG1376	ErfK ybiS ycfS ynhG family protein
JLF40_RS09920	COG0626	cystathionine gamma-synthase activity
JLF40_RS09935	COG2011	ABC-type metal ion transport system permease component
JLF40_RS09940	COG1464	Belongs to the NlpA lipoprotein family
JLF40_RS09950	COG0765	amino acid transport
JLF40_RS09955	COG0765	amino acid transport
JLF40_RS09965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS09980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JLF40_RS09990	COG4529	Protein conserved in bacteria
JLF40_RS10005	COG0534	Mate efflux family protein
JLF40_RS10010	COG0307	riboflavin synthase, alpha
JLF40_RS10015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JLF40_RS10020	COG2814	Major facilitator Superfamily
JLF40_RS10025	COG0583	DNA-binding transcription factor activity
JLF40_RS10040	COG2814	Major facilitator Superfamily
JLF40_RS10050	COG0791	NLP P60 protein
JLF40_RS10055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JLF40_RS10060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JLF40_RS10065	COG0346	lactoylglutathione lyase activity
JLF40_RS10070	COG1902	pentaerythritol trinitrate reductase activity
JLF40_RS10075	COG1309	transcriptional regulator
JLF40_RS10085	COG3313	Fe-S protein
JLF40_RS10090	COG4989	oxidoreductase activity
JLF40_RS10095	COG2032	superoxide dismutase activity
JLF40_RS10100	COG1289	transmembrane transporter activity
JLF40_RS10105	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS10120	COG3706	GGDEF domain
JLF40_RS10130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JLF40_RS10135	COG3895	Periplasmic Protein
JLF40_RS10140	COG0259	pyridoxamine-phosphate oxidase activity
JLF40_RS10145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JLF40_RS10150	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JLF40_RS10155	COG0625	glutathione transferase activity
JLF40_RS10160	COG3104	oligopeptide transport
JLF40_RS10165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JLF40_RS10175	COG4659	FMN binding
JLF40_RS10215	COG0673	inositol 2-dehydrogenase activity
JLF40_RS10220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JLF40_RS10225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JLF40_RS10235	COG0582	viral genome integration into host DNA
JLF40_RS10430	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JLF40_RS10460	COG3646	Phage regulatory protein
JLF40_RS10485	COG0494	nUDIX hydrolase
JLF40_RS10615	COG1609	Transcriptional regulator
JLF40_RS10620	COG5339	Protein conserved in bacteria
JLF40_RS10625	COG1482	cell wall glycoprotein biosynthetic process
JLF40_RS10630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JLF40_RS10630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JLF40_RS10635	COG0114	fumarate hydratase activity
JLF40_RS10645	COG2205	protein histidine kinase activity
JLF40_RS10655	COG0745	RESPONSE REGULATOR receiver
JLF40_RS10660	COG3136	membrane protein required for alginate biosynthesis
JLF40_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS10670	COG0531	amino acid
JLF40_RS10680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JLF40_RS10685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JLF40_RS10705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JLF40_RS10725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JLF40_RS10800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JLF40_RS10820	COG5002	protein histidine kinase activity
JLF40_RS10820	COG3850	Histidine kinase
JLF40_RS10835	COG1403	HNH endonuclease
JLF40_RS10840	COG0384	phenazine biosynthesis protein PhzF
JLF40_RS10845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS10850	COG0628	permease
JLF40_RS10855	COG2076	Multidrug Resistance protein
JLF40_RS10865	COG5001	Diguanylate cyclase
JLF40_RS10870	COG3591	Belongs to the peptidase S1B family
JLF40_RS10885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JLF40_RS10890	COG2814	Major facilitator Superfamily
JLF40_RS10895	COG0583	DNA-binding transcription factor activity
JLF40_RS10900	COG1940	carbohydrate kinase activity
JLF40_RS10905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JLF40_RS10940	COG0625	glutathione transferase activity
JLF40_RS10955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JLF40_RS10965	COG3468	outer membrane autotransporter barrel domain protein
JLF40_RS10975	COG3141	response to X-ray
JLF40_RS10980	COG2207	Transcriptional regulator
JLF40_RS10980	COG3708	Transcriptional regulator
JLF40_RS10985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS11005	COG0745	RESPONSE REGULATOR receiver
JLF40_RS11030	COG3381	protein complex oligomerization
JLF40_RS11035	COG0243	molybdopterin cofactor binding
JLF40_RS11050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS11060	COG1742	UPF0060 membrane protein
JLF40_RS11065	COG4948	Mandelate Racemase Muconate Lactonizing
JLF40_RS11070	COG1063	alcohol dehydrogenase
JLF40_RS11075	COG0477	Major facilitator Superfamily
JLF40_RS11080	COG0246	Mannitol dehydrogenase
JLF40_RS11090	COG0589	response to stress
JLF40_RS11095	COG1802	Transcriptional regulator
JLF40_RS11100	COG4221	oxidoreductase activity
JLF40_RS11110	COG5001	Diguanylate cyclase
JLF40_RS11110	COG3300	MHYT domain
JLF40_RS11130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JLF40_RS11145	COG2911	Protein conserved in bacteria
JLF40_RS11155	COG3784	Protein of unknown function (DUF1318)
JLF40_RS11160	COG2207	Transcriptional regulator
JLF40_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS11170	COG3706	GGDEF domain
JLF40_RS11175	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JLF40_RS11185	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS11185	COG2030	dehydratase
JLF40_RS11190	COG3396	Phenylacetate-CoA oxygenase
JLF40_RS11195	COG3460	Phenylacetate-CoA oxygenase
JLF40_RS11200	COG3396	Phenylacetate-CoA oxygenase
JLF40_RS11205	COG2151	metal-sulfur cluster biosynthetic enzyme
JLF40_RS11210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JLF40_RS11215	COG1024	Enoyl-CoA hydratase
JLF40_RS11220	COG1024	Enoyl-CoA hydratase
JLF40_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
JLF40_RS11230	COG2050	protein possibly involved in aromatic compounds catabolism
JLF40_RS11235	COG0183	Belongs to the thiolase family
JLF40_RS11240	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JLF40_RS11245	COG3327	negative regulation of DNA-templated transcription, initiation
JLF40_RS11250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JLF40_RS11255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JLF40_RS11260	COG0386	Belongs to the glutathione peroxidase family
JLF40_RS11275	COG2807	transmembrane transport
JLF40_RS11280	COG1846	Transcriptional regulator
JLF40_RS11305	COG2249	NAD(P)H dehydrogenase (quinone) activity
JLF40_RS11330	COG4221	oxidoreductase activity
JLF40_RS11335	COG0789	Transcriptional regulator
JLF40_RS11345	COG0583	DNA-binding transcription factor activity
JLF40_RS11350	COG1902	pentaerythritol trinitrate reductase activity
JLF40_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS11380	COG1733	regulation of RNA biosynthetic process
JLF40_RS11385	COG0346	lactoylglutathione lyase activity
JLF40_RS11410	COG0300	oxidoreductase activity
JLF40_RS11425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JLF40_RS11455	COG0583	DNA-binding transcription factor activity
JLF40_RS11485	COG3122	Protein conserved in bacteria
JLF40_RS11500	COG1643	Atp-dependent helicase
JLF40_RS11505	COG4122	O-methyltransferase activity
JLF40_RS11510	COG1538	Outer membrane efflux protein
JLF40_RS11525	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JLF40_RS11530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JLF40_RS11535	COG3038	cytochrome b561
JLF40_RS11540	COG0673	inositol 2-dehydrogenase activity
JLF40_RS11545	COG1349	DNA-binding transcription factor activity
JLF40_RS11560	COG3547	Transposase (IS116 IS110 IS902 family)
JLF40_RS11595	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JLF40_RS11600	COG0456	acetyltransferase
JLF40_RS11605	COG0583	DNA-binding transcription factor activity
JLF40_RS11610	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JLF40_RS11625	COG0402	S-adenosylhomocysteine deaminase activity
JLF40_RS11630	COG2814	Major facilitator Superfamily
JLF40_RS11650	COG0840	transmembrane signaling receptor activity
JLF40_RS11655	COG4993	Dehydrogenase
JLF40_RS11660	COG0583	DNA-binding transcription factor activity
JLF40_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS11670	COG3111	PFAM Bacterial OB fold (BOF) protein
JLF40_RS11685	COG1546	Belongs to the CinA family
JLF40_RS11700	COG1294	oxidase, subunit
JLF40_RS11705	COG1271	oxidase subunit
JLF40_RS11710	COG3546	catalase activity
JLF40_RS11715	COG3685	Protein conserved in bacteria
JLF40_RS11725	COG3685	Protein conserved in bacteria
JLF40_RS11730	COG3729	General stress protein
JLF40_RS11735	COG5383	Protein conserved in bacteria
JLF40_RS11740	COG2272	Belongs to the type-B carboxylesterase lipase family
JLF40_RS11750	COG0436	Aminotransferase
JLF40_RS11760	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JLF40_RS11765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS11770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JLF40_RS11775	COG0500	methyltransferase
JLF40_RS11780	COG2195	Cleaves the N-terminal amino acid of tripeptides
JLF40_RS11785	COG0747	negative chemotaxis
JLF40_RS11805	COG3135	benzoate transporter
JLF40_RS11810	COG1396	sequence-specific DNA binding
JLF40_RS11815	COG0826	peptidase U32
JLF40_RS11830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JLF40_RS11845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JLF40_RS11865	COG1129	ABC transporter
JLF40_RS11875	COG3443	Belongs to the bacterial solute-binding protein 9 family
JLF40_RS11880	COG2814	Major facilitator Superfamily
JLF40_RS11885	COG0697	spore germination
JLF40_RS11900	COG1846	Transcriptional regulator
JLF40_RS11910	COG2814	Major facilitator Superfamily
JLF40_RS11930	COG0583	DNA-binding transcription factor activity
JLF40_RS11935	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS11945	COG2066	Belongs to the glutaminase family
JLF40_RS11955	COG2199	diguanylate cyclase activity
JLF40_RS11960	COG3706	GGDEF domain
JLF40_RS11970	COG0246	Mannitol dehydrogenase
JLF40_RS11975	COG3781	membrane
JLF40_RS12000	COG0456	acetyltransferase
JLF40_RS12005	COG0596	Alpha beta hydrolase
JLF40_RS12015	COG2205	protein histidine kinase activity
JLF40_RS12025	COG4106	trans-aconitate 2-methyltransferase activity
JLF40_RS12035	COG2771	luxR family
JLF40_RS12040	COG0494	nUDIX hydrolase
JLF40_RS12045	COG1349	DNA-binding transcription factor activity
JLF40_RS12070	COG0583	DNA-binding transcription factor activity
JLF40_RS12305	COG0745	RESPONSE REGULATOR receiver
JLF40_RS12315	COG0583	DNA-binding transcription factor activity
JLF40_RS12320	COG2814	Major facilitator Superfamily
JLF40_RS12355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JLF40_RS12365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JLF40_RS12380	COG0583	DNA-binding transcription factor activity
JLF40_RS12385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JLF40_RS12395	COG1366	Belongs to the anti-sigma-factor antagonist family
JLF40_RS12445	COG3250	beta-galactosidase activity
JLF40_RS12450	COG4628	conserved protein (DUF2132)
JLF40_RS12455	COG1649	PFAM Uncharacterised BCR, COG1649
JLF40_RS12460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JLF40_RS12490	COG0194	GDP metabolic process
JLF40_RS12495	COG0840	transmembrane signaling receptor activity
JLF40_RS12525	COG2200	EAL domain
JLF40_RS12540	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JLF40_RS12545	COG0747	negative chemotaxis
JLF40_RS12550	COG0601	transmembrane transport
JLF40_RS12555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS12560	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS12565	COG4608	Belongs to the ABC transporter superfamily
JLF40_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS12580	COG1764	response to oxidative stress
JLF40_RS12610	COG0281	malic enzyme
JLF40_RS12615	COG0488	(ABC) transporter
JLF40_RS12620	COG1064	alcohol dehydrogenase
JLF40_RS12635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS12645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS12655	COG2814	Major facilitator Superfamily
JLF40_RS12685	COG2864	formate dehydrogenase
JLF40_RS12690	COG0437	4 iron, 4 sulfur cluster binding
JLF40_RS12750	COG3158	transport of potassium into the cell
JLF40_RS12765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JLF40_RS12770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JLF40_RS12775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JLF40_RS12780	COG0640	Transcriptional regulator
JLF40_RS12800	COG3493	citrate carrier protein
JLF40_RS12815	COG1560	Kdo2-lipid A biosynthetic process
JLF40_RS12820	COG1942	4-Oxalocrotonate Tautomerase
JLF40_RS12825	COG0625	glutathione transferase activity
JLF40_RS12835	COG1126	abc transporter atp-binding protein
JLF40_RS12840	COG0765	amino acid transport
JLF40_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS12855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS12860	COG1473	amidohydrolase
JLF40_RS12865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS12870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JLF40_RS12870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JLF40_RS12875	COG0840	transmembrane signaling receptor activity
JLF40_RS12900	COG4772	TonB-dependent receptor
JLF40_RS12905	COG1802	Transcriptional regulator
JLF40_RS12910	COG2130	NADP-dependent
JLF40_RS12920	COG1247	-acetyltransferase
JLF40_RS12925	COG3238	Protein conserved in bacteria
JLF40_RS12935	COG0747	negative chemotaxis
JLF40_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS12970	COG1177	transmembrane transport
JLF40_RS12975	COG1176	ABC-type spermidine putrescine transport system, permease component I
JLF40_RS12980	COG3842	ATPase activity
JLF40_RS12985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JLF40_RS12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JLF40_RS13000	COG1271	oxidase subunit
JLF40_RS13005	COG1294	oxidase, subunit
JLF40_RS13015	COG3187	Heat shock protein
JLF40_RS13020	COG3042	response to heat
JLF40_RS13025	COG0674	pyruvate-flavodoxin oxidoreductase activity
JLF40_RS13025	COG1013	pyruvate-flavodoxin oxidoreductase activity
JLF40_RS13025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JLF40_RS13025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JLF40_RS13030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JLF40_RS13065	COG2200	EAL domain
JLF40_RS13080	COG0513	Belongs to the DEAD box helicase family
JLF40_RS13090	COG0840	transmembrane signaling receptor activity
JLF40_RS13100	COG3706	GGDEF domain
JLF40_RS13110	COG0693	protein deglycase activity
JLF40_RS13115	COG4166	transmembrane transport
JLF40_RS13120	COG2866	Carboxypeptidase
JLF40_RS13125	COG4948	Mandelate Racemase Muconate Lactonizing
JLF40_RS13130	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JLF40_RS13145	COG3768	UPF0283 membrane protein
JLF40_RS13150	COG3106	COG3106 Predicted ATPase
JLF40_RS13155	COG1609	Transcriptional regulator
JLF40_RS13165	COG3842	ATPase activity
JLF40_RS13170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JLF40_RS13175	COG1554	hydrolase, family 65, central catalytic
JLF40_RS13180	COG0673	inositol 2-dehydrogenase activity
JLF40_RS13185	COG1082	Xylose isomerase domain protein TIM barrel
JLF40_RS13190	COG1063	alcohol dehydrogenase
JLF40_RS13195	COG0395	ABC-type sugar transport system, permease component
JLF40_RS13200	COG1175	transmembrane transport
JLF40_RS13205	COG1653	transport
JLF40_RS13210	COG0366	Alpha amylase catalytic
JLF40_RS13220	COG1983	PspC domain protein
JLF40_RS13230	COG1842	Phage shock protein A
JLF40_RS13235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JLF40_RS13250	COG4171	peptide transport system, permease
JLF40_RS13270	COG5002	protein histidine kinase activity
JLF40_RS13275	COG0745	RESPONSE REGULATOR receiver
JLF40_RS13290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS13295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JLF40_RS13300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JLF40_RS13300	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JLF40_RS13305	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JLF40_RS13310	COG5001	Diguanylate cyclase
JLF40_RS13315	COG1024	Enoyl-CoA hydratase
JLF40_RS13325	COG1349	DNA-binding transcription factor activity
JLF40_RS13335	COG0023	Translation Initiation Factor
JLF40_RS13340	COG0284	orotidine-5'-phosphate decarboxylase activity
JLF40_RS13345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JLF40_RS13350	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JLF40_RS13355	COG0671	phosphoesterase, PA-phosphatase related
JLF40_RS13365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JLF40_RS13395	COG0616	signal peptide processing
JLF40_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS13405	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JLF40_RS13415	COG0009	L-threonylcarbamoyladenylate synthase
JLF40_RS13420	COG0613	PHP domain protein
JLF40_RS13435	COG0512	Glutamine amidotransferase of anthranilate synthase
JLF40_RS13435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JLF40_RS13445	COG0133	tryptophan synthase activity
JLF40_RS13450	COG0159	tryptophan synthase activity
JLF40_RS13455	COG2391	methyltransferase activity
JLF40_RS13460	COG0425	Belongs to the sulfur carrier protein TusA family
JLF40_RS13470	COG3047	cAMP biosynthetic process
JLF40_RS13480	COG0727	PFAM Uncharacterised protein family (UPF0153)
JLF40_RS13505	COG2350	Protein conserved in bacteria
JLF40_RS13515	COG1280	lysine exporter protein (LysE YggA)
JLF40_RS13530	COG3099	Belongs to the UPF0263 family
JLF40_RS13535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JLF40_RS13540	COG4608	Belongs to the ABC transporter superfamily
JLF40_RS13545	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS13555	COG0601	transmembrane transport
JLF40_RS13565	COG2095	MarC family integral membrane protein
JLF40_RS13570	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS13570	COG1454	alcohol dehydrogenase
JLF40_RS13575	COG1435	thymidine kinase activity
JLF40_RS13585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JLF40_RS13590	COG0745	RESPONSE REGULATOR receiver
JLF40_RS13595	COG1752	Esterase of the alpha-beta hydrolase superfamily
JLF40_RS13600	COG3012	SEC-C Motif Domain Protein
JLF40_RS13605	COG0788	formyltetrahydrofolate deformylase activity
JLF40_RS13615	COG1522	sequence-specific DNA binding
JLF40_RS13620	COG0697	spore germination
JLF40_RS13625	COG2181	nitrate reductase activity
JLF40_RS13630	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JLF40_RS13635	COG1140	nitrate reductase beta subunit
JLF40_RS13640	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JLF40_RS13645	COG2223	nitrite transmembrane transporter activity
JLF40_RS13650	COG3850	Histidine kinase
JLF40_RS13655	COG2197	response regulator
JLF40_RS13660	COG4932	domain protein
JLF40_RS13665	COG0243	molybdopterin cofactor binding
JLF40_RS13670	COG2146	nitrite reductase [NAD(P)H] activity
JLF40_RS13670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JLF40_RS13675	COG1116	anion transmembrane transporter activity
JLF40_RS13685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JLF40_RS13690	COG3707	response regulator
JLF40_RS13695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JLF40_RS13700	COG0840	transmembrane signaling receptor activity
JLF40_RS13710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JLF40_RS13715	COG4572	Cation transport regulator
JLF40_RS13720	COG0387	Pfam Sodium calcium exchanger
JLF40_RS13725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JLF40_RS13740	COG2890	protein-(glutamine-N5) methyltransferase activity
JLF40_RS13750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JLF40_RS13755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JLF40_RS13760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JLF40_RS13770	COG0659	secondary active sulfate transmembrane transporter activity
JLF40_RS13785	COG0193	aminoacyl-tRNA hydrolase activity
JLF40_RS13790	COG0012	GTP binding
JLF40_RS13805	COG3209	COG3209 Rhs family protein
JLF40_RS13835	COG0515	serine threonine protein kinase
JLF40_RS13945	COG0243	molybdopterin cofactor binding
JLF40_RS13950	COG0583	DNA-binding transcription factor activity
JLF40_RS13965	COG4977	sequence-specific DNA binding
JLF40_RS13970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JLF40_RS13975	COG2814	Major facilitator Superfamily
JLF40_RS13990	COG4774	siderophore transport
JLF40_RS14005	COG0741	lytic transglycosylase activity
JLF40_RS14010	COG1619	proteins homologs of microcin C7 resistance protein MccF
JLF40_RS14015	COG3263	regulation of cellular component size
JLF40_RS14020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JLF40_RS14025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JLF40_RS14030	COG2719	SpoVR family
JLF40_RS14040	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JLF40_RS14050	COG2983	Belongs to the UPF0260 family
JLF40_RS14055	COG0179	Fumarylacetoacetate (FAA) hydrolase
JLF40_RS14060	COG3100	YcgL domain-containing protein
JLF40_RS14065	COG0850	regulation of cytokinetic process
JLF40_RS14070	COG2894	cell division
JLF40_RS14075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JLF40_RS14080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JLF40_RS14085	COG0318	PFAM AMP-dependent synthetase and ligase
JLF40_RS14090	COG3065	identical protein binding
JLF40_RS14095	COG1214	PFAM Peptidase M22, glycoprotease
JLF40_RS14100	COG1199	ATP-dependent helicase activity
JLF40_RS14105	COG0251	oxidation-reduction process
JLF40_RS14115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JLF40_RS14125	COG1760	l-serine dehydratase
JLF40_RS14130	COG2200	EAL domain
JLF40_RS14135	COG1253	flavin adenine dinucleotide binding
JLF40_RS14140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS14140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS14145	COG3715	PTS system
JLF40_RS14150	COG3716	PTS system mannose fructose sorbose family IID component
JLF40_RS14155	COG4811	Protein of unknown function (DUF986)
JLF40_RS14160	COG1971	Probably functions as a manganese efflux pump
JLF40_RS14165	COG2226	methyltransferase
JLF40_RS14170	COG0768	penicillin binding
JLF40_RS14205	COG1414	Transcriptional regulator
JLF40_RS14210	COG2814	Major facilitator Superfamily
JLF40_RS14215	COG0501	Belongs to the peptidase M48B family
JLF40_RS14230	COG1956	GAF domain-containing protein
JLF40_RS14235	COG2995	paraquat-inducible protein a
JLF40_RS14240	COG3008	intermembrane lipid transfer
JLF40_RS14245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JLF40_RS14245	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JLF40_RS14260	COG2990	Protein conserved in bacteria
JLF40_RS14275	COG1276	copper resistance
JLF40_RS14280	COG2372	response to copper ion
JLF40_RS14290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JLF40_RS14295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JLF40_RS14300	COG1770	oligopeptidase
JLF40_RS14305	COG2979	Protein of unknown function (DUF533)
JLF40_RS14315	COG0800	Aldolase
JLF40_RS14320	COG0129	dihydroxy-acid dehydratase activity
JLF40_RS14325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JLF40_RS14330	COG1737	Transcriptional regulator
JLF40_RS14340	COG1560	Kdo2-lipid A biosynthetic process
JLF40_RS14345	COG0739	heme binding
JLF40_RS14350	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JLF40_RS14360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JLF40_RS14365	COG2255	four-way junction helicase activity
JLF40_RS14370	COG0632	four-way junction helicase activity
JLF40_RS14385	COG0494	nUDIX hydrolase
JLF40_RS14395	COG1335	isochorismatase
JLF40_RS14400	COG1801	Protein of unknown function DUF72
JLF40_RS14405	COG3788	relative of glutathione S-transferase, MAPEG superfamily
JLF40_RS14410	COG2226	methyltransferase
JLF40_RS14415	COG0500	methyltransferase
JLF40_RS14420	COG3142	Participates in the control of copper homeostasis
JLF40_RS14425	COG3102	Protein conserved in bacteria
JLF40_RS14430	COG0018	arginyl-trna synthetase
JLF40_RS14435	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JLF40_RS14465	COG3121	Chaperone
JLF40_RS14470	COG3188	usher protein
JLF40_RS14485	COG0745	RESPONSE REGULATOR receiver
JLF40_RS14500	COG0840	transmembrane signaling receptor activity
JLF40_RS14535	COG1301	dicarboxylic acid transport
JLF40_RS14575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JLF40_RS14585	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS14595	COG1879	ABC-type sugar transport system periplasmic component
JLF40_RS14600	COG1528	Iron-storage protein
JLF40_RS14605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JLF40_RS14625	COG1528	Iron-storage protein
JLF40_RS14635	COG0814	amino acid
JLF40_RS14640	COG3318	Belongs to the UPF0149 family
JLF40_RS14640	COG3012	SEC-C Motif Domain Protein
JLF40_RS14660	COG0411	ABC transporter
JLF40_RS14700	COG2197	response regulator
JLF40_RS14710	COG2197	response regulator
JLF40_RS14715	COG1126	abc transporter atp-binding protein
JLF40_RS14720	COG0765	amino acid transport
JLF40_RS14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS14770	COG0366	Alpha amylase catalytic
JLF40_RS14780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JLF40_RS14815	COG1677	Flagellar hook-basal body complex protein FliE
JLF40_RS14825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JLF40_RS14835	COG1157	protein secretion by the type III secretion system
JLF40_RS14875	COG1987	bacterial-type flagellum assembly
JLF40_RS14885	COG2197	response regulator
JLF40_RS14910	COG5475	Uncharacterized small protein (DUF2158)
JLF40_RS14915	COG2354	Protein conserved in bacteria
JLF40_RS14920	COG0697	spore germination
JLF40_RS14925	COG3727	T/G mismatch-specific endonuclease activity
JLF40_RS14930	COG0270	DNA (cytosine-5-)-methyltransferase activity
JLF40_RS14935	COG1418	mRNA catabolic process
JLF40_RS14940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JLF40_RS14950	COG3290	protein histidine kinase activity
JLF40_RS14955	COG4565	transcriptional regulatory protein
JLF40_RS14975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JLF40_RS14975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JLF40_RS14990	COG0583	DNA-binding transcription factor activity
JLF40_RS14995	COG3046	protein related to deoxyribodipyrimidine photolyase
JLF40_RS15045	COG0582	viral genome integration into host DNA
JLF40_RS15050	COG2207	Transcriptional regulator
JLF40_RS15055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JLF40_RS15060	COG1845	cytochrome c oxidase, subunit III
JLF40_RS15065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JLF40_RS15070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JLF40_RS15075	COG2814	Major facilitator Superfamily
JLF40_RS15080	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS15110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JLF40_RS15130	COG3451	type IV secretory pathway VirB4
JLF40_RS15160	COG3504	Conjugal transfer protein
JLF40_RS15170	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
JLF40_RS15190	COG4227	nucleotidyltransferase activity
JLF40_RS15255	COG0251	oxidation-reduction process
JLF40_RS15270	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
JLF40_RS15300	COG1376	ErfK ybiS ycfS ynhG family protein
JLF40_RS15305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JLF40_RS15310	COG0589	response to stress
JLF40_RS15320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS15335	COG0477	Major facilitator Superfamily
JLF40_RS15340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JLF40_RS15345	COG0006	proline dipeptidase activity
JLF40_RS15355	COG0534	Mate efflux family protein
JLF40_RS15375	COG1289	transmembrane transporter activity
JLF40_RS15380	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JLF40_RS15390	COG2925	Exonuclease
JLF40_RS15395	COG0531	amino acid
JLF40_RS15405	COG0583	DNA-binding transcription factor activity
JLF40_RS15410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JLF40_RS15420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JLF40_RS15430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JLF40_RS15435	COG0131	Imidazoleglycerol-phosphate dehydratase
JLF40_RS15435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JLF40_RS15440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JLF40_RS15445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JLF40_RS15450	COG0107	imidazoleglycerol-phosphate synthase activity
JLF40_RS15540	COG1091	dTDP-4-dehydrorhamnose reductase activity
JLF40_RS15560	COG0438	transferase activity, transferring glycosyl groups
JLF40_RS15565	COG2327	Polysaccharide pyruvyl transferase
JLF40_RS15570	COG2244	polysaccharide biosynthetic process
JLF40_RS15575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JLF40_RS15580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JLF40_RS15590	COG0297	glycogen (starch) synthase activity
JLF40_RS15595	COG1051	belongs to the nudix hydrolase family
JLF40_RS15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JLF40_RS15605	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JLF40_RS15610	COG0110	maltose O-acetyltransferase activity
JLF40_RS15615	COG1216	Glycosyl transferase, family 2
JLF40_RS15625	COG0438	transferase activity, transferring glycosyl groups
JLF40_RS15630	COG1045	serine acetyltransferase
JLF40_RS15635	COG0463	Glycosyl transferase, family 2
JLF40_RS15640	COG3206	protein involved in exopolysaccharide biosynthesis
JLF40_RS15640	COG0489	protein tyrosine kinase activity
JLF40_RS15655	COG1253	flavin adenine dinucleotide binding
JLF40_RS15660	COG2982	Protein involved in outer membrane biogenesis
JLF40_RS15665	COG0717	Belongs to the dCTP deaminase family
JLF40_RS15675	COG5001	Diguanylate cyclase
JLF40_RS15675	COG5002	protein histidine kinase activity
JLF40_RS15675	COG3447	MASE1 domain protein
JLF40_RS15680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JLF40_RS15685	COG0443	Heat shock 70 kDa protein
JLF40_RS15690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS15695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS15700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS15705	COG0477	Major facilitator Superfamily
JLF40_RS15710	COG2205	protein histidine kinase activity
JLF40_RS15715	COG0745	RESPONSE REGULATOR receiver
JLF40_RS15725	COG0826	peptidase U32
JLF40_RS15730	COG1683	Conserved Protein
JLF40_RS15735	COG1597	lipid kinase activity
JLF40_RS15740	COG1830	Aldolase
JLF40_RS15745	COG2211	Major facilitator Superfamily
JLF40_RS15750	COG1397	ADP-ribosylglycohydrolase
JLF40_RS15755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JLF40_RS15760	COG2188	Transcriptional regulator
JLF40_RS15765	COG0351	phosphomethylpyrimidine kinase
JLF40_RS15770	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JLF40_RS15785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JLF40_RS15790	COG0076	glutamate decarboxylase activity
JLF40_RS15795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JLF40_RS15800	COG0489	protein tyrosine kinase activity
JLF40_RS15800	COG3206	protein involved in exopolysaccharide biosynthesis
JLF40_RS15805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JLF40_RS15810	COG1596	polysaccharide export
JLF40_RS15815	COG5455	response to cobalt ion
JLF40_RS15825	COG0489	protein tyrosine kinase activity
JLF40_RS15830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JLF40_RS15830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JLF40_RS15835	COG4807	Protein conserved in bacteria
JLF40_RS15845	COG3275	phosphorelay sensor kinase activity
JLF40_RS15850	COG0789	Transcriptional regulator
JLF40_RS15860	COG1174	glycine betaine transport
JLF40_RS15865	COG1125	glycine betaine transport
JLF40_RS15870	COG1174	glycine betaine transport
JLF40_RS15875	COG1732	Glycine betaine
JLF40_RS15880	COG1472	Belongs to the glycosyl hydrolase 3 family
JLF40_RS15885	COG0277	FAD linked oxidase domain protein
JLF40_RS15895	COG1686	Belongs to the peptidase S11 family
JLF40_RS15905	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS15915	COG1538	Outer membrane efflux protein
JLF40_RS15920	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS15935	COG3659	wide pore channel activity
JLF40_RS15940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JLF40_RS15945	COG2207	Transcriptional regulator
JLF40_RS15960	COG1346	cytolysis
JLF40_RS15965	COG0295	cytidine deaminase activity
JLF40_RS15970	COG2949	membrane
JLF40_RS15975	COG0174	glutamine synthetase
JLF40_RS15985	COG1129	ABC transporter
JLF40_RS16000	COG2311	Membrane
JLF40_RS16010	COG0477	Major facilitator Superfamily
JLF40_RS16020	COG4771	TonB-dependent receptor
JLF40_RS16025	COG0833	amino acid
JLF40_RS16030	COG0583	DNA-binding transcription factor activity
JLF40_RS16035	COG2855	membrane
JLF40_RS16040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JLF40_RS16045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JLF40_RS16045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JLF40_RS16045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JLF40_RS16050	COG1105	Belongs to the carbohydrate kinase PfkB family
JLF40_RS16055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS16055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS16065	COG2026	Addiction module toxin, RelE StbE family
JLF40_RS16070	COG3077	Addiction module antitoxin, RelB DinJ family
JLF40_RS16085	COG3328	transposase activity
JLF40_RS16090	COG2801	Transposase and inactivated derivatives
JLF40_RS16105	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JLF40_RS16110	COG1312	Catalyzes the dehydration of D-mannonate
JLF40_RS16115	COG0246	Mannitol dehydrogenase
JLF40_RS16120	COG0523	cobalamin synthesis protein
JLF40_RS16125	COG0671	phosphoesterase, PA-phosphatase related
JLF40_RS16130	COG0791	NLP P60 protein
JLF40_RS16135	COG2200	EAL domain
JLF40_RS16140	COG4166	transmembrane transport
JLF40_RS16145	COG4174	ABC transporter (Permease)
JLF40_RS16150	COG4239	(ABC) transporter, permease
JLF40_RS16155	COG4172	Belongs to the ABC transporter superfamily
JLF40_RS16165	COG2814	Major facilitator Superfamily
JLF40_RS16170	COG1187	pseudouridine synthase activity
JLF40_RS16175	COG1061	Type III restriction enzyme res subunit
JLF40_RS16185	COG3081	Nucleoid-associated protein
JLF40_RS16190	COG3082	Protein of unknown function (DUF1414)
JLF40_RS16210	COG3182	Iron-regulated membrane protein
JLF40_RS16220	COG0579	oxidoreductase
JLF40_RS16225	COG0659	secondary active sulfate transmembrane transporter activity
JLF40_RS16230	COG2239	Acts as a magnesium transporter
JLF40_RS16235	COG4615	Cyclic peptide transporter
JLF40_RS16240	COG3145	DNA-N1-methyladenine dioxygenase activity
JLF40_RS16245	COG2169	Transcriptional regulator
JLF40_RS16245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JLF40_RS16260	COG2198	Histidine kinase
JLF40_RS16260	COG0642	Histidine kinase
JLF40_RS16270	COG0784	Response regulator, receiver
JLF40_RS16270	COG2205	protein histidine kinase activity
JLF40_RS16280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JLF40_RS16295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JLF40_RS16300	COG0584	glycerophosphoryl diester phosphodiesterase
JLF40_RS16305	COG2271	Major facilitator Superfamily
JLF40_RS16310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JLF40_RS16315	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JLF40_RS16320	COG0247	lactate metabolic process
JLF40_RS16340	COG1441	menaquinone biosynthetic process
JLF40_RS16350	COG0596	Alpha beta hydrolase
JLF40_RS16355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JLF40_RS16360	COG1169	isochorismate synthase
JLF40_RS16365	COG4575	ribosome binding
JLF40_RS16370	COG2153	protein acetylation
JLF40_RS16375	COG1234	tRNA 3'-trailer cleavage
JLF40_RS16380	COG0835	chemotaxis
JLF40_RS16380	COG0784	Response regulator, receiver
JLF40_RS16385	COG1007	ATP synthesis coupled electron transport
JLF40_RS16390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JLF40_RS16395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JLF40_RS16400	COG0713	ATP synthesis coupled electron transport
JLF40_RS16405	COG0839	Belongs to the complex I subunit 6 family
JLF40_RS16415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JLF40_RS16445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JLF40_RS16450	COG0583	DNA-binding transcription factor activity
JLF40_RS16455	COG0436	Aminotransferase
JLF40_RS16465	COG0471	metal ion transport
JLF40_RS16465	COG0490	domain, Protein
JLF40_RS16470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JLF40_RS16495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JLF40_RS16500	COG3959	Transketolase, thiamine diphosphate binding domain
JLF40_RS16505	COG3037	sugar-specific permease SgaT UlaA
JLF40_RS16515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS16520	COG1609	Transcriptional regulator
JLF40_RS16530	COG0622	Phosphoesterase
JLF40_RS16535	COG0625	glutathione transferase activity
JLF40_RS16540	COG0625	glutathione transferase activity
JLF40_RS16545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JLF40_RS16550	COG1090	epimerase
JLF40_RS16555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS16560	COG4598	ABC transporter
JLF40_RS16565	COG4160	amino acid transport
JLF40_RS16575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS16585	COG0163	prenyltransferase activity
JLF40_RS16590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JLF40_RS16595	COG1286	toxin biosynthetic process
JLF40_RS16600	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JLF40_RS16605	COG0285	dihydrofolate synthase activity
JLF40_RS16615	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS16620	COG0101	tRNA pseudouridine synthase activity
JLF40_RS16625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JLF40_RS16645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JLF40_RS16650	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JLF40_RS16650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JLF40_RS16660	COG3101	peptidyl-lysine hydroxylation
JLF40_RS16665	COG0730	response to heat
JLF40_RS16685	COG2840	Smr protein MutS2
JLF40_RS16690	COG2062	phosphohistidine phosphatase, SixA
JLF40_RS16695	COG1250	3-hydroxyacyl-CoA dehydrogenase
JLF40_RS16695	COG1024	Enoyl-CoA hydratase
JLF40_RS16705	COG3691	Protein conserved in bacteria
JLF40_RS16710	COG2067	long-chain fatty acid transport protein
JLF40_RS16720	COG2116	formate transmembrane transporter activity
JLF40_RS16730	COG0582	viral genome integration into host DNA
JLF40_RS16870	COG3501	Rhs element vgr protein
JLF40_RS16890	COG2885	chlorophyll binding
JLF40_RS16920	COG1560	Kdo2-lipid A biosynthetic process
JLF40_RS16930	COG0436	Aminotransferase
JLF40_RS16935	COG3275	phosphorelay sensor kinase activity
JLF40_RS16940	COG3279	Response regulator of the LytR AlgR family
JLF40_RS16945	COG0837	glucose binding
JLF40_RS16955	COG3961	Belongs to the TPP enzyme family
JLF40_RS16960	COG0667	Aldo Keto reductase
JLF40_RS16970	COG1914	H( )-stimulated, divalent metal cation uptake system
JLF40_RS16975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JLF40_RS16980	COG2199	diguanylate cyclase activity
JLF40_RS16980	COG2200	EAL domain
JLF40_RS16995	COG3415	Transposase
JLF40_RS17000	COG3415	Transposase
JLF40_RS17005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JLF40_RS17035	COG0583	DNA-binding transcription factor activity
JLF40_RS17040	COG0385	Bile acid
JLF40_RS17045	COG3530	Putative quorum-sensing-regulated virulence factor
JLF40_RS17050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JLF40_RS17055	COG3115	cell septum assembly
JLF40_RS17070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS17095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JLF40_RS17100	COG4208	sulfate ABC transporter
JLF40_RS17105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JLF40_RS17110	COG4150	thiosulfate binding
JLF40_RS17115	COG2837	iron assimilation
JLF40_RS17135	COG0860	N-Acetylmuramoyl-L-alanine amidase
JLF40_RS17140	COG0408	coproporphyrinogen oxidase activity
JLF40_RS17155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JLF40_RS17160	COG5342	invasion associated locus B
JLF40_RS17165	COG0494	nUDIX hydrolase
JLF40_RS17170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JLF40_RS17170	COG0493	'glutamate synthase
JLF40_RS17175	COG3850	Histidine kinase
JLF40_RS17180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS17190	COG1393	Belongs to the ArsC family
JLF40_RS17195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JLF40_RS17205	COG0400	carboxylic ester hydrolase activity
JLF40_RS17210	COG1444	tRNA N-acetyltransferase activity
JLF40_RS17215	COG2321	neutral zinc metallopeptidase
JLF40_RS17220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JLF40_RS17225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JLF40_RS17235	COG2716	regulation of RNA biosynthetic process
JLF40_RS17240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JLF40_RS17245	COG0628	permease
JLF40_RS17250	COG4783	chaperone-mediated protein folding
JLF40_RS17255	COG1393	Belongs to the ArsC family
JLF40_RS17270	COG1446	asparaginase
JLF40_RS17275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JLF40_RS17285	COG2233	PERMEase
JLF40_RS17290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JLF40_RS17295	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS17305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JLF40_RS17320	COG2200	EAL domain
JLF40_RS17330	COG0583	DNA-binding transcription factor activity
JLF40_RS17355	COG2814	Major facilitator Superfamily
JLF40_RS17360	COG3718	enzyme involved in inositol metabolism
JLF40_RS17370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JLF40_RS17375	COG0673	inositol 2-dehydrogenase activity
JLF40_RS17380	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS17395	COG0673	inositol 2-dehydrogenase activity
JLF40_RS17400	COG3962	Belongs to the TPP enzyme family
JLF40_RS17435	COG0516	GMP reductase activity
JLF40_RS17435	COG0517	IMP dehydrogenase activity
JLF40_RS17440	COG1570	exodeoxyribonuclease VII activity
JLF40_RS17455	COG1645	bacterial-type flagellum-dependent swarming motility
JLF40_RS17535	COG1160	GTP binding
JLF40_RS17545	COG2976	Protein conserved in bacteria
JLF40_RS17550	COG0124	histidyl-tRNA synthetase
JLF40_RS17565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JLF40_RS17575	COG4953	penicillin-binding protein 1C
JLF40_RS17580	COG2373	Large extracellular alpha-helical protein
JLF40_RS17585	COG2190	(PTS) system
JLF40_RS17585	COG1263	PTS System
JLF40_RS17585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS17595	COG2897	thiosulfate sulfurtransferase activity
JLF40_RS17600	COG1737	Transcriptional regulator
JLF40_RS17610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JLF40_RS17615	COG2975	iron-sulfur cluster assembly
JLF40_RS17620	COG0633	Ferredoxin
JLF40_RS17625	COG0443	Heat shock 70 kDa protein
JLF40_RS17630	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JLF40_RS17635	COG0316	Belongs to the HesB IscA family
JLF40_RS17640	COG0822	iron-sulfur transferase activity
JLF40_RS17645	COG1104	cysteine desulfurase activity
JLF40_RS17650	COG1959	2 iron, 2 sulfur cluster binding
JLF40_RS17675	COG3711	transcriptional antiterminator
JLF40_RS17680	COG2814	Major facilitator Superfamily
JLF40_RS17685	COG2259	Doxx family
JLF40_RS17695	COG1017	nitric oxide dioxygenase activity
JLF40_RS17695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JLF40_RS17700	COG0347	Belongs to the P(II) protein family
JLF40_RS17705	COG2204	response regulator
JLF40_RS17710	COG3170	Tfp pilus assembly protein FimV
JLF40_RS17715	COG2205	protein histidine kinase activity
JLF40_RS17720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JLF40_RS17720	COG0047	phosphoribosylformylglycinamidine synthase activity
JLF40_RS17725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JLF40_RS17735	COG0560	Phosphoserine phosphatase
JLF40_RS17740	COG1263	PTS System
JLF40_RS17740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS17745	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JLF40_RS17750	COG1737	Transcriptional regulator
JLF40_RS17755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JLF40_RS17765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JLF40_RS17770	COG1381	Involved in DNA repair and RecF pathway recombination
JLF40_RS17785	COG0681	Belongs to the peptidase S26 family
JLF40_RS17795	COG3086	response to oxidative stress
JLF40_RS17805	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JLF40_RS17820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JLF40_RS17825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JLF40_RS17830	COG0513	Belongs to the DEAD box helicase family
JLF40_RS17835	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JLF40_RS17845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JLF40_RS17850	COG3118	belongs to the thioredoxin family
JLF40_RS17855	COG3148	PFAM DTW domain containing protein
JLF40_RS17860	COG1042	CoA-binding domain protein
JLF40_RS17860	COG0045	succinate-CoA ligase (ADP-forming) activity
JLF40_RS17860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS17865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JLF40_RS17870	COG5544	Lipoprotein
JLF40_RS17875	COG0477	Major facilitator Superfamily
JLF40_RS17900	COG0542	response to heat
JLF40_RS17915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JLF40_RS17920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JLF40_RS17930	COG0077	Prephenate dehydratase
JLF40_RS17930	COG1605	Chorismate mutase
JLF40_RS17940	COG0287	Prephenate dehydrogenase
JLF40_RS17940	COG1605	Chorismate mutase
JLF40_RS17945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JLF40_RS17960	COG2199	diguanylate cyclase activity
JLF40_RS17965	COG2885	chlorophyll binding
JLF40_RS17985	COG0336	Belongs to the RNA methyltransferase TrmD family
JLF40_RS17990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JLF40_RS18000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JLF40_RS18005	COG4137	Cytochrome C assembly protein
JLF40_RS18010	COG4536	flavin adenine dinucleotide binding
JLF40_RS18015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JLF40_RS18020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JLF40_RS18025	COG0497	DNA recombination
JLF40_RS18040	COG2867	negative regulation of translational initiation
JLF40_RS18065	COG3328	transposase activity
JLF40_RS18280	COG0484	heat shock protein binding
JLF40_RS18285	COG0305	Participates in initiation and elongation during chromosome replication
JLF40_RS18290	COG1484	DNA-dependent DNA replication
JLF40_RS18345	COG0582	viral genome integration into host DNA
JLF40_RS18360	COG0582	viral genome integration into host DNA
JLF40_RS18435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS18440	COG3549	Plasmid maintenance system killer
JLF40_RS18445	COG3093	addiction module antidote protein HigA
JLF40_RS18450	COG1051	belongs to the nudix hydrolase family
JLF40_RS18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JLF40_RS18475	COG0583	DNA-binding transcription factor activity
JLF40_RS18485	COG2226	methyltransferase
JLF40_RS18490	COG0402	S-adenosylhomocysteine deaminase activity
JLF40_RS18495	COG0549	Belongs to the carbamate kinase family
JLF40_RS18505	COG1304	FMN binding
JLF40_RS18510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JLF40_RS18515	COG0666	response to abiotic stimulus
JLF40_RS18520	COG0583	DNA-binding transcription factor activity
JLF40_RS18525	COG0401	homolog of Blt101
JLF40_RS18530	COG0640	Transcriptional regulator
JLF40_RS18535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JLF40_RS18560	COG4575	ribosome binding
JLF40_RS18570	COG1780	Probably involved in ribonucleotide reductase function
JLF40_RS18575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JLF40_RS18585	COG4175	Glycine betaine
JLF40_RS18590	COG4176	ABC-type proline glycine betaine transport system permease component
JLF40_RS18600	COG2814	Major facilitator Superfamily
JLF40_RS18605	COG1846	Transcriptional regulator
JLF40_RS18610	COG1566	PFAM secretion protein HlyD family protein
JLF40_RS18615	COG2814	Major facilitator Superfamily
JLF40_RS18620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JLF40_RS18635	COG2918	glutathione biosynthetic process
JLF40_RS18640	COG1238	metal cluster binding
JLF40_RS18645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JLF40_RS18675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JLF40_RS18680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JLF40_RS18690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JLF40_RS18695	COG1546	Belongs to the CinA family
JLF40_RS18705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JLF40_RS18715	COG2951	lytic endotransglycosylase activity
JLF40_RS18720	COG3730	PTS system glucitol sorbitol-specific
JLF40_RS18725	COG3732	PTS system glucitol sorbitol-specific
JLF40_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS18740	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS18745	COG1349	DNA-binding transcription factor activity
JLF40_RS18755	COG3604	Transcriptional regulator
JLF40_RS18760	COG1773	rubredoxin
JLF40_RS18760	COG0426	domain, Protein
JLF40_RS18765	COG0446	pyridine nucleotide-disulphide oxidoreductase
JLF40_RS18770	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JLF40_RS18775	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JLF40_RS18780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JLF40_RS18785	COG1609	Transcriptional regulator
JLF40_RS18790	COG1263	PTS System
JLF40_RS18790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS18795	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS18800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JLF40_RS18810	COG3260	NADH ubiquinone oxidoreductase 20
JLF40_RS18815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JLF40_RS18820	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
JLF40_RS18820	COG3261	NADH dehydrogenase
JLF40_RS18825	COG0650	Formate hydrogenlyase subunit 4
JLF40_RS18830	COG0651	ATP synthesis coupled electron transport
JLF40_RS18835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JLF40_RS18850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JLF40_RS18855	COG0298	carbon dioxide binding
JLF40_RS18860	COG0409	Hydrogenase expression formation protein
JLF40_RS18865	COG0309	Hydrogenase expression formation protein (HypE)
JLF40_RS18880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS18885	COG1120	ATPase activity
JLF40_RS18905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JLF40_RS18915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JLF40_RS18920	COG0163	prenyltransferase activity
JLF40_RS18935	COG0477	Major facilitator Superfamily
JLF40_RS18950	COG1388	LysM domain
JLF40_RS18950	COG4942	peptidase
JLF40_RS18965	COG0585	pseudouridine synthase activity
JLF40_RS18975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JLF40_RS18980	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JLF40_RS18990	COG0529	Catalyzes the synthesis of activated sulfate
JLF40_RS19010	COG2234	aminopeptidase activity
JLF40_RS19025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JLF40_RS19030	COG0720	synthase
JLF40_RS19035	COG0602	queuosine metabolic process
JLF40_RS19040	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JLF40_RS19045	COG2190	(PTS) system
JLF40_RS19045	COG1263	PTS System
JLF40_RS19045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JLF40_RS19070	COG3956	TIGRFAM MazG family protein
JLF40_RS19075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JLF40_RS19080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JLF40_RS19085	COG3850	Histidine kinase
JLF40_RS19085	COG4999	Histidine kinase
JLF40_RS19085	COG3437	response regulator, receiver
JLF40_RS19085	COG2205	protein histidine kinase activity
JLF40_RS19090	COG1929	Belongs to the glycerate kinase type-1 family
JLF40_RS19095	COG4948	Mandelate Racemase Muconate Lactonizing
JLF40_RS19100	COG4948	Mandelate Racemase Muconate Lactonizing
JLF40_RS19105	COG2271	Major facilitator Superfamily
JLF40_RS19110	COG0716	FMN binding
JLF40_RS19115	COG0564	pseudouridine synthase activity
JLF40_RS19120	COG3098	single-species biofilm formation
JLF40_RS19135	COG1611	Belongs to the LOG family
JLF40_RS19140	COG0814	amino acid
JLF40_RS19145	COG1760	l-serine dehydratase
JLF40_RS19155	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JLF40_RS19160	COG2363	Small membrane protein
JLF40_RS19165	COG0583	DNA-binding transcription factor activity
JLF40_RS19175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JLF40_RS19180	COG2166	iron-sulfur cluster assembly
JLF40_RS19185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JLF40_RS19190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JLF40_RS19200	COG0860	N-Acetylmuramoyl-L-alanine amidase
JLF40_RS19205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JLF40_RS19205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JLF40_RS19210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JLF40_RS19215	COG1074	ATP-dependent DNA helicase activity
JLF40_RS19225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JLF40_RS19230	COG4967	type IV pilus modification protein PilV
JLF40_RS19240	COG4795	General secretion pathway protein
JLF40_RS19245	COG2165	general secretion pathway protein
JLF40_RS19250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JLF40_RS19255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JLF40_RS19265	COG0494	nUDIX hydrolase
JLF40_RS19270	COG3066	DNA modification
JLF40_RS19280	COG0667	Aldo Keto reductase
JLF40_RS19285	COG0477	Major facilitator Superfamily
JLF40_RS19290	COG0204	Acyl-transferase
JLF40_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
JLF40_RS19295	COG1609	Transcriptional regulator
JLF40_RS19305	COG1609	Transcriptional regulator
JLF40_RS19315	COG0583	DNA-binding transcription factor activity
JLF40_RS19320	COG1794	racemase activity, acting on amino acids and derivatives
JLF40_RS19325	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
JLF40_RS19330	COG2814	Major facilitator Superfamily
JLF40_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS19345	COG0183	Belongs to the thiolase family
JLF40_RS19360	COG0814	amino acid
JLF40_RS19375	COG2388	GCN5-related N-acetyl-transferase
JLF40_RS19380	COG3592	Divergent 4Fe-4S mono-cluster
JLF40_RS19390	COG4565	transcriptional regulatory protein
JLF40_RS19405	COG3842	ATPase activity
JLF40_RS19430	COG4942	peptidase
JLF40_RS19435	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JLF40_RS19440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JLF40_RS19450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JLF40_RS19460	COG4974	Belongs to the 'phage' integrase family
JLF40_RS19475	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JLF40_RS19480	COG0354	folic acid binding
JLF40_RS19485	COG1272	protein, Hemolysin III
JLF40_RS19495	COG1737	Transcriptional regulator
JLF40_RS19500	COG2723	6-phospho-beta-galactosidase activity
JLF40_RS19505	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS19510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JLF40_RS19510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JLF40_RS19520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JLF40_RS19525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JLF40_RS19530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JLF40_RS19535	COG0006	proline dipeptidase activity
JLF40_RS19545	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JLF40_RS19555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JLF40_RS19560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JLF40_RS19565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JLF40_RS19570	COG0583	DNA-binding transcription factor activity
JLF40_RS19575	COG2968	Membrane
JLF40_RS19580	COG1279	arginine transmembrane transporter activity
JLF40_RS19585	COG0668	transmembrane transport
JLF40_RS19590	COG0191	fructose-bisphosphate aldolase activity
JLF40_RS19600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JLF40_RS19605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JLF40_RS19610	COG0501	Belongs to the peptidase M48B family
JLF40_RS19620	COG0010	Belongs to the arginase family
JLF40_RS19625	COG1166	arginine decarboxylase activity
JLF40_RS19645	COG2814	Major facilitator Superfamily
JLF40_RS19650	COG3091	SprT-like family
JLF40_RS19655	COG2356	endonuclease I
JLF40_RS19660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JLF40_RS19675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JLF40_RS19680	COG2805	Type II/IV secretion system protein
JLF40_RS19685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JLF40_RS19690	COG0762	integral membrane protein
JLF40_RS19695	COG1872	DUF167
JLF40_RS19705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JLF40_RS19710	COG2852	Protein conserved in bacteria
JLF40_RS19720	COG3171	Protein conserved in bacteria
JLF40_RS19730	COG1194	a g-specific adenine glycosylase
JLF40_RS19740	COG0741	lytic transglycosylase activity
JLF40_RS19745	COG2211	Major facilitator Superfamily
JLF40_RS19750	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JLF40_RS19770	COG3052	prosthetic group binding
JLF40_RS19780	COG0179	Fumarylacetoacetate (FAA) hydrolase
JLF40_RS19785	COG3493	citrate carrier protein
JLF40_RS19800	COG1982	Orn Lys Arg decarboxylase major
JLF40_RS19805	COG1811	Na channel or pump
JLF40_RS19855	COG0457	Tetratricopeptide repeat
JLF40_RS19860	COG0726	polysaccharide deacetylase
JLF40_RS19860	COG1649	PFAM Uncharacterised BCR, COG1649
JLF40_RS19865	COG1215	transferase activity, transferring glycosyl groups
JLF40_RS19875	COG0754	glutathionylspermidine amidase activity
JLF40_RS19880	COG4608	Belongs to the ABC transporter superfamily
JLF40_RS19885	COG0444	Belongs to the ABC transporter superfamily
JLF40_RS19890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JLF40_RS19895	COG0601	transmembrane transport
JLF40_RS19905	COG0625	glutathione transferase activity
JLF40_RS19935	COG2862	Uncharacterized protein family, UPF0114
JLF40_RS19955	COG0848	biopolymer transport protein
JLF40_RS19965	COG0626	cystathionine gamma-synthase activity
JLF40_RS19970	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS19975	COG2207	Transcriptional regulator
JLF40_RS19980	COG1979	alcohol dehydrogenase
JLF40_RS20050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JLF40_RS20060	COG1595	DNA-templated transcription, initiation
JLF40_RS20065	COG3712	iron ion homeostasis
JLF40_RS20070	COG4772	TonB-dependent receptor
JLF40_RS20075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JLF40_RS20080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS20085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS20090	COG1120	ATPase activity
JLF40_RS20095	COG3436	PFAM IS66 Orf2 family protein
JLF40_RS20115	COG1609	Transcriptional regulator
JLF40_RS20125	COG2223	nitrite transmembrane transporter activity
JLF40_RS20145	COG3547	Transposase (IS116 IS110 IS902 family)
JLF40_RS20150	COG2801	Transposase and inactivated derivatives
JLF40_RS20200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JLF40_RS20220	COG3111	PFAM Bacterial OB fold (BOF) protein
JLF40_RS20235	COG2249	NAD(P)H dehydrogenase (quinone) activity
JLF40_RS20240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JLF40_RS20255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS20260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JLF40_RS20265	COG1120	ATPase activity
JLF40_RS20270	COG4774	siderophore transport
JLF40_RS20275	COG0187	DNA topoisomerase II activity
JLF40_RS20280	COG3150	esterase
JLF40_RS20285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JLF40_RS20290	COG3151	Protein conserved in bacteria
JLF40_RS20295	COG0494	nUDIX hydrolase
JLF40_RS20310	COG0754	glutathionylspermidine amidase activity
JLF40_RS20315	COG3384	dioxygenase
JLF40_RS20325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JLF40_RS20335	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JLF40_RS20335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JLF40_RS20345	COG3025	triphosphatase activity
JLF40_RS20350	COG4991	sh3 domain protein
JLF40_RS20355	COG0617	tRNA 3'-terminal CCA addition
JLF40_RS20360	COG1968	undecaprenyl-diphosphatase activity
JLF40_RS20365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JLF40_RS20375	COG0477	Major facilitator Superfamily
JLF40_RS20380	COG1846	Transcriptional regulator
JLF40_RS20385	COG0657	acetylesterase activity
JLF40_RS20390	COG0829	nickel cation binding
JLF40_RS20395	COG0831	urea catabolic process
JLF40_RS20400	COG0832	Belongs to the urease beta subunit family
JLF40_RS20405	COG0804	urea catabolic process
JLF40_RS20410	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JLF40_RS20420	COG0830	nickel cation binding
JLF40_RS20425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JLF40_RS20435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JLF40_RS20440	COG0358	DNA primase activity
JLF40_RS20450	COG3663	DNA glycosylase
JLF40_RS20500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS20515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JLF40_RS20580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JLF40_RS20605	COG2375	cellular response to nickel ion
JLF40_RS20610	COG1695	Transcriptional regulator
JLF40_RS20615	COG0840	transmembrane signaling receptor activity
JLF40_RS20620	COG0840	transmembrane signaling receptor activity
JLF40_RS20625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JLF40_RS20645	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JLF40_RS20650	COG1830	Aldolase
JLF40_RS20655	COG1879	ABC-type sugar transport system periplasmic component
JLF40_RS20660	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS20665	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS20670	COG1129	ABC transporter
JLF40_RS20675	COG2390	Transcriptional regulator
JLF40_RS20680	COG1070	Carbohydrate kinase
JLF40_RS20685	COG1902	pentaerythritol trinitrate reductase activity
JLF40_RS20685	COG0446	pyridine nucleotide-disulphide oxidoreductase
JLF40_RS20695	COG1451	nucleotide metabolic process
JLF40_RS20700	COG0673	inositol 2-dehydrogenase activity
JLF40_RS20705	COG0861	Integral membrane protein TerC family
JLF40_RS20715	COG2721	sulfolactate sulfo-lyase activity
JLF40_RS20725	COG2271	Major facilitator Superfamily
JLF40_RS20730	COG2186	Transcriptional regulator
JLF40_RS20735	COG0586	Pfam SNARE associated Golgi protein
JLF40_RS20745	COG1422	Protein of unknown function (DUF1090)
JLF40_RS20750	COG4575	ribosome binding
JLF40_RS20755	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
JLF40_RS20765	COG2259	Doxx family
JLF40_RS20770	COG0435	Glutathione S-transferase
JLF40_RS20775	COG3152	Membrane
JLF40_RS20780	COG0583	DNA-binding transcription factor activity
JLF40_RS20785	COG1741	Belongs to the pirin family
JLF40_RS20795	COG1882	Formate acetyltransferase
JLF40_RS20800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JLF40_RS20805	COG0814	amino acid
JLF40_RS20810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JLF40_RS20815	COG0583	DNA-binding transcription factor activity
JLF40_RS20825	COG2084	Dehydrogenase
JLF40_RS20835	COG2721	sulfolactate sulfo-lyase activity
JLF40_RS20840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JLF40_RS20845	COG3107	peptidoglycan biosynthetic process
JLF40_RS20850	COG0792	nuclease activity
JLF40_RS20855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JLF40_RS20860	COG2823	Periplasmic or secreted lipoprotein
JLF40_RS20865	COG0701	Predicted permease
JLF40_RS20870	COG0702	epimerase
JLF40_RS20875	COG0693	protein deglycase activity
JLF40_RS20880	COG3787	Belongs to the UPF0306 family
JLF40_RS20885	COG2827	Endonuclease containing a URI domain
JLF40_RS20890	COG3153	acetyltransferase
JLF40_RS20895	COG3154	lipid carrier protein
JLF40_RS20900	COG0826	peptidase U32
JLF40_RS20905	COG0826	peptidase U32
JLF40_RS20910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JLF40_RS20915	COG0814	amino acid
JLF40_RS20920	COG0513	Belongs to the DEAD box helicase family
JLF40_RS20935	COG1185	polyribonucleotide nucleotidyltransferase activity
JLF40_RS20940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JLF40_RS20945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JLF40_RS20950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JLF40_RS20955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JLF40_RS20975	COG0137	argininosuccinate synthase activity
JLF40_RS20985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JLF40_RS20990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JLF40_RS20995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JLF40_RS21005	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JLF40_RS21010	COG1534	Rna-binding protein
JLF40_RS21020	COG2027	D-alanyl-D-alanine carboxypeptidase
JLF40_RS21025	COG0745	RESPONSE REGULATOR receiver
JLF40_RS21030	COG0642	Histidine kinase
JLF40_RS21035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JLF40_RS21040	COG0697	spore germination
JLF40_RS21050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JLF40_RS21055	COG0142	geranyltranstransferase activity
JLF40_RS21060	COG3423	Transcriptional regulator
JLF40_RS21065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JLF40_RS21070	COG5007	Belongs to the BolA IbaG family
JLF40_RS21075	COG3113	response to antibiotic
JLF40_RS21080	COG2854	intermembrane phospholipid transfer
JLF40_RS21085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JLF40_RS21090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JLF40_RS21095	COG1127	ABC transporter
JLF40_RS21100	COG0530	calcium, potassium:sodium antiporter activity
JLF40_RS21110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JLF40_RS21115	COG3117	lipopolysaccharide transmembrane transporter activity
JLF40_RS21120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JLF40_RS21125	COG1137	ATPase activity
JLF40_RS21130	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JLF40_RS21150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JLF40_RS21160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JLF40_RS21165	COG5002	protein histidine kinase activity
JLF40_RS21165	COG2198	Histidine kinase
JLF40_RS21165	COG0784	Response regulator, receiver
JLF40_RS21170	COG0795	lipopolysaccharide-transporting ATPase activity
JLF40_RS21175	COG0795	lipopolysaccharide-transporting ATPase activity
JLF40_RS21180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JLF40_RS21185	COG2927	DNA polymerase III (CHI subunit)
JLF40_RS21200	COG1064	alcohol dehydrogenase
JLF40_RS21210	COG0433	COG0433 Predicted ATPase
JLF40_RS21215	COG1242	4 iron, 4 sulfur cluster binding
JLF40_RS21220	COG0069	glutamate synthase activity
JLF40_RS21220	COG0067	glutamate synthase
JLF40_RS21220	COG0070	glutamate synthase
JLF40_RS21225	COG0493	'glutamate synthase
JLF40_RS21230	COG2969	positive regulation of protein catabolic process
JLF40_RS21235	COG0625	glutathione transferase activity
JLF40_RS21240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JLF40_RS21250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JLF40_RS21255	COG3105	Protein conserved in bacteria
JLF40_RS21260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JLF40_RS21265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JLF40_RS21270	COG0039	L-malate dehydrogenase activity
JLF40_RS21275	COG1438	arginine binding
JLF40_RS21290	COG2732	(Barnase) inhibitor
JLF40_RS21295	COG1012	belongs to the aldehyde dehydrogenase family
JLF40_RS21300	COG1289	transmembrane transporter activity
JLF40_RS21315	COG0583	DNA-binding transcription factor activity
JLF40_RS21320	COG0312	modulator of DNA gyrase
JLF40_RS21325	COG3164	Protein of unknown function
JLF40_RS21340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JLF40_RS21345	COG1792	Involved in formation and maintenance of cell shape
JLF40_RS21350	COG1077	Cell shape determining protein MreB Mrl
JLF40_RS21355	COG2199	diguanylate cyclase activity
JLF40_RS21355	COG2200	EAL domain
JLF40_RS21360	COG0604	alcohol dehydrogenase
JLF40_RS21370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JLF40_RS21375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JLF40_RS21380	COG0511	ligase activity, forming carbon-carbon bonds
JLF40_RS21385	COG0439	Biotin carboxylase
JLF40_RS21390	COG3924	membrane
JLF40_RS21395	COG4145	pantothenate transmembrane transporter activity
JLF40_RS21400	COG2264	protein methyltransferase activity
JLF40_RS21435	COG3039	Transposase
JLF40_RS21440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS21445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JLF40_RS21455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JLF40_RS21460	COG4597	amino acid ABC transporter
JLF40_RS21465	COG0765	amino acid transport
JLF40_RS21470	COG1126	abc transporter atp-binding protein
JLF40_RS21500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JLF40_RS21510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JLF40_RS21515	COG0009	L-threonylcarbamoyladenylate synthase
JLF40_RS21520	COG0551	DNA topoisomerase type I activity
JLF40_RS21525	COG2922	Belongs to the Smg family
JLF40_RS21530	COG0758	DNA mediated transformation
JLF40_RS21535	COG0242	peptide deformylase activity
JLF40_RS21540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JLF40_RS21545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JLF40_RS21545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JLF40_RS21560	COG3036	rescue of stalled ribosome
JLF40_RS21565	COG0789	Transcriptional regulator
JLF40_RS21580	COG0202	RNA polymerase activity
JLF40_RS21590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JLF40_RS21605	COG0201	protein transport
JLF40_RS21615	COG1841	ribosomal large subunit assembly
JLF40_RS21630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JLF40_RS21635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JLF40_RS21665	COG0255	Belongs to the universal ribosomal protein uL29 family
JLF40_RS21670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JLF40_RS21710	COG0051	transcription antitermination factor activity, RNA binding
JLF40_RS21750	COG2168	tRNA wobble position uridine thiolation
JLF40_RS21755	COG2923	Belongs to the DsrF TusC family
JLF40_RS21760	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JLF40_RS21765	COG2964	Protein conserved in bacteria
JLF40_RS21770	COG0545	Peptidyl-prolyl cis-trans isomerase
JLF40_RS21780	COG1047	Peptidyl-prolyl cis-trans
JLF40_RS21785	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JLF40_RS21790	COG0475	glutathione-regulated potassium exporter activity
JLF40_RS21790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JLF40_RS21795	COG2249	NAD(P)H dehydrogenase (quinone) activity
JLF40_RS21800	COG0488	(ABC) transporter
JLF40_RS21805	COG0429	hydrolase of the alpha beta-hydrolase fold
JLF40_RS21810	COG3089	Belongs to the UPF0270 family
JLF40_RS21815	COG3954	Phosphoribulokinase
JLF40_RS21820	COG1765	OsmC-like protein
JLF40_RS21830	COG1289	transmembrane transporter activity
JLF40_RS21835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JLF40_RS21845	COG2184	nucleotidyltransferase activity
JLF40_RS21855	COG0738	Major facilitator superfamily
JLF40_RS21860	COG0402	S-adenosylhomocysteine deaminase activity
JLF40_RS21865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JLF40_RS21875	COG1648	precorrin-2 dehydrogenase activity
JLF40_RS21875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JLF40_RS21895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JLF40_RS21900	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JLF40_RS21905	COG3266	domain, Protein
JLF40_RS21910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JLF40_RS21915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JLF40_RS21920	COG4796	Type ii and iii secretion system protein
JLF40_RS21940	COG4972	Pilus assembly protein
JLF40_RS21945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JLF40_RS21950	COG0494	nUDIX hydrolase
JLF40_RS21960	COG1011	Hydrolase
JLF40_RS21965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JLF40_RS21970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JLF40_RS21975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JLF40_RS21990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JLF40_RS21995	COG2183	response to ionizing radiation
JLF40_RS22000	COG1918	ferrous iron import across plasma membrane
JLF40_RS22025	COG1040	competence protein
JLF40_RS22035	COG2610	gluconate transmembrane transporter activity
JLF40_RS22040	COG1640	4-alpha-glucanotransferase
JLF40_RS22045	COG0058	SHG alpha-glucan phosphorylase activity
JLF40_RS22050	COG2909	trisaccharide binding
JLF40_RS22055	COG1349	DNA-binding transcription factor activity
JLF40_RS22060	COG0705	Rhomboid family
JLF40_RS22065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JLF40_RS22070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JLF40_RS22075	COG0058	SHG alpha-glucan phosphorylase activity
JLF40_RS22080	COG0297	glycogen (starch) synthase activity
JLF40_RS22085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JLF40_RS22090	COG1523	belongs to the glycosyl hydrolase 13 family
JLF40_RS22095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JLF40_RS22100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JLF40_RS22105	COG2095	MarC family integral membrane protein
JLF40_RS22110	COG0425	Belongs to the sulfur carrier protein TusA family
JLF40_RS22115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JLF40_RS22125	COG0477	Major facilitator Superfamily
JLF40_RS22130	COG0628	permease
JLF40_RS22160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JLF40_RS22170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JLF40_RS22170	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JLF40_RS22180	COG1216	Glycosyl transferase, family 2
JLF40_RS22215	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS22220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JLF40_RS22225	COG2091	lysine biosynthetic process via aminoadipic acid
JLF40_RS22265	COG3479	Phenolic acid decarboxylase
JLF40_RS22275	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS22280	COG0791	NLP P60 protein
JLF40_RS22305	COG1414	Transcriptional regulator
JLF40_RS22310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JLF40_RS22315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JLF40_RS22320	COG2081	HI0933 family
JLF40_RS22325	COG0306	phosphate transporter
JLF40_RS22340	COG0589	response to stress
JLF40_RS22345	COG0742	ribosomal rna small subunit methyltransferase
JLF40_RS22350	COG0339	signal peptide processing
JLF40_RS22355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JLF40_RS22360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JLF40_RS22375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JLF40_RS22380	COG1028	Short-chain dehydrogenase reductase Sdr
JLF40_RS22385	COG0583	DNA-binding transcription factor activity
JLF40_RS22390	COG1295	ribonuclease BN
JLF40_RS22395	COG0477	Major facilitator Superfamily
JLF40_RS22400	COG2982	Protein involved in outer membrane biogenesis
JLF40_RS22405	COG2200	EAL domain
JLF40_RS22415	COG0612	Peptidase, M16
JLF40_RS22420	COG1301	dicarboxylic acid transport
JLF40_RS22425	COG2199	diguanylate cyclase activity
JLF40_RS22425	COG2200	EAL domain
JLF40_RS22430	COG0457	Tetratricopeptide repeat
JLF40_RS22430	COG3118	belongs to the thioredoxin family
JLF40_RS22435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JLF40_RS22440	COG1215	transferase activity, transferring glycosyl groups
JLF40_RS22445	COG1215	transferase activity, transferring glycosyl groups
JLF40_RS22470	COG2194	sulfuric ester hydrolase activity
JLF40_RS22485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JLF40_RS22515	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
JLF40_RS22525	COG1739	Uncharacterized protein family UPF0029
JLF40_RS22530	COG0006	proline dipeptidase activity
JLF40_RS22535	COG1024	Enoyl-CoA hydratase
JLF40_RS22535	COG1250	3-hydroxyacyl-CoA dehydrogenase
JLF40_RS22540	COG0183	Belongs to the thiolase family
JLF40_RS22550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JLF40_RS22560	COG0084	hydrolase, TatD family'
JLF40_RS22565	COG0805	protein transport
JLF40_RS22570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JLF40_RS22575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JLF40_RS22580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JLF40_RS22590	COG2226	methyltransferase
JLF40_RS22595	COG1322	Protein conserved in bacteria
JLF40_RS22605	COG0412	Dienelactone hydrolase
JLF40_RS22610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JLF40_RS22615	COG0583	DNA-binding transcription factor activity
JLF40_RS22620	COG0697	spore germination
JLF40_RS22625	COG0561	phosphatase activity
JLF40_RS22630	COG2267	carboxylic ester hydrolase activity
JLF40_RS22635	COG1280	lysine exporter protein (LysE YggA)
JLF40_RS22640	COG1280	lysine exporter protein (LysE YggA)
JLF40_RS22675	COG1011	Hydrolase
JLF40_RS22710	COG0181	hydroxymethylbilane synthase activity
JLF40_RS22720	COG2959	enzyme of heme biosynthesis
JLF40_RS22725	COG3071	HemY protein
JLF40_RS22760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JLF40_RS22775	COG2244	polysaccharide biosynthetic process
JLF40_RS22780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JLF40_RS22785	COG0456	acetyltransferase
JLF40_RS22790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JLF40_RS22795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JLF40_RS22805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JLF40_RS22810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JLF40_RS22815	COG3118	belongs to the thioredoxin family
JLF40_RS22825	COG0248	Ppx GppA phosphatase
JLF40_RS22835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JLF40_RS22840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JLF40_RS22850	COG0583	DNA-binding transcription factor activity
JLF40_RS22855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JLF40_RS22865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JLF40_RS22870	COG3978	acetolactate synthase activity
JLF40_RS22890	COG0606	chelatase, subunit chli
JLF40_RS22895	COG3085	chromosome segregation
JLF40_RS22945	COG4206	TonB-dependent receptor
JLF40_RS22950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JLF40_RS22970	COG0583	DNA-binding transcription factor activity
JLF40_RS22975	COG0165	Argininosuccinate lyase
JLF40_RS22985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JLF40_RS22990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JLF40_RS22995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JLF40_RS23000	COG2207	Transcriptional regulator
JLF40_RS23010	COG0371	Dehydrogenase
JLF40_RS23015	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JLF40_RS23025	COG0527	aspartate kinase activity
JLF40_RS23025	COG0460	homoserine dehydrogenase
JLF40_RS23030	COG0626	cystathionine gamma-synthase activity
JLF40_RS23040	COG0254	rRNA binding
JLF40_RS23045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JLF40_RS23050	COG1609	Transcriptional regulator
JLF40_RS23055	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JLF40_RS23070	COG1575	Belongs to the MenA family. Type 1 subfamily
JLF40_RS23080	COG3074	FtsZ-dependent cytokinesis
JLF40_RS23090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JLF40_RS23095	COG1494	fructose-1,6-bisphosphatase
JLF40_RS23105	COG3152	Membrane
JLF40_RS23115	COG0149	triose-phosphate isomerase activity
JLF40_RS23125	COG2134	cdp-diacylglycerol pyrophosphatase
JLF40_RS23135	COG0205	6-phosphofructokinase activity
JLF40_RS23145	COG3678	ATP-independent chaperone mediated protein folding
JLF40_RS23150	COG0745	RESPONSE REGULATOR receiver
JLF40_RS23155	COG2205	protein histidine kinase activity
JLF40_RS23160	COG2258	MOSC domain
JLF40_RS23165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JLF40_RS23175	COG1917	Cupin 2, conserved barrel domain protein
JLF40_RS23175	COG4977	sequence-specific DNA binding
JLF40_RS23180	COG4977	sequence-specific DNA binding
JLF40_RS23185	COG1070	Carbohydrate kinase
JLF40_RS23190	COG4806	L-rhamnose isomerase
JLF40_RS23195	COG0235	Class ii aldolase
JLF40_RS23200	COG1454	alcohol dehydrogenase
JLF40_RS23205	COG3254	rhamnose metabolic process
JLF40_RS23210	COG2211	Major facilitator Superfamily
JLF40_RS23230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JLF40_RS23255	COG0437	4 iron, 4 sulfur cluster binding
JLF40_RS23260	COG2864	formate dehydrogenase
JLF40_RS23265	COG3058	Necessary for formate dehydrogenase activity
JLF40_RS23275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JLF40_RS23285	COG0456	acetyltransferase
JLF40_RS23300	COG1011	Hydrolase
JLF40_RS23335	COG3852	Histidine kinase
JLF40_RS23350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JLF40_RS23355	COG3078	GTPase activator activity
JLF40_RS23370	COG0204	Acyl-transferase
JLF40_RS23380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JLF40_RS23385	COG3084	Protein conserved in bacteria
JLF40_RS23390	COG0746	molybdenum cofactor guanylyltransferase activity
JLF40_RS23395	COG1763	Mo-molybdopterin cofactor biosynthetic process
JLF40_RS23420	COG2186	Transcriptional regulator
JLF40_RS23425	COG0477	Major facilitator Superfamily
JLF40_RS23430	COG1609	Transcriptional regulator
JLF40_RS23435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JLF40_RS23440	COG1879	ABC-type sugar transport system periplasmic component
JLF40_RS23445	COG1172	Belongs to the binding-protein-dependent transport system permease family
JLF40_RS23450	COG1129	ABC transporter
JLF40_RS23455	COG1869	D-ribose catabolic process
JLF40_RS23460	COG3158	transport of potassium into the cell
JLF40_RS23470	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JLF40_RS23475	COG2502	aspartate--ammonia ligase
JLF40_RS23480	COG1522	sequence-specific DNA binding
JLF40_RS23485	COG0716	FMN binding
JLF40_RS23490	COG0445	tRNA wobble uridine modification
JLF40_RS23495	COG0357	Ribosomal RNA small subunit methyltransferase G
JLF40_RS23500	COG3312	ion transport
JLF40_RS23505	COG0356	it plays a direct role in the translocation of protons across the membrane
JLF40_RS23515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JLF40_RS23520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JLF40_RS23525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JLF40_RS23535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JLF40_RS23540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JLF40_RS23545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JLF40_RS23555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JLF40_RS23560	COG0573	inorganic phosphate transmembrane transporter activity
JLF40_RS23565	COG0581	inorganic phosphate transmembrane transporter activity
JLF40_RS23570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JLF40_RS23575	COG0704	Plays a role in the regulation of phosphate uptake
JLF40_RS23580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JLF40_RS23585	COG2252	PERMEase
JLF40_RS23590	COG0431	NADPH-dependent FMN reductase
JLF40_RS23595	COG2091	lysine biosynthetic process via aminoadipic acid
JLF40_RS23610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JLF40_RS23615	COG0706	membrane insertase activity
JLF40_RS23695	COG1192	Involved in chromosome partitioning
JLF40_RS23785	COG0210	DNA helicase
JLF40_RS23935	COG4245	von Willebrand factor, type A
JLF40_RS23940	COG4245	von Willebrand factor, type A
JLF40_RS23970	COG1358	cellular component organization or biogenesis
JLF40_RS24090	COG3550	peptidyl-serine autophosphorylation
JLF40_RS24155	COG1357	PFAM Pentapeptide repeats (8 copies)
JLF40_RS24235	COG0789	Transcriptional regulator
JLF40_RS24305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JLF40_RS24355	COG0840	transmembrane signaling receptor activity
JLF40_RS24370	COG1349	DNA-binding transcription factor activity
JLF40_RS24420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JLF40_RS24425	COG3077	Addiction module antitoxin, RelB DinJ family
JLF40_RS24430	COG2026	Addiction module toxin, RelE StbE family
JLF40_RS24590	COG3157	Type VI secretion system effector, Hcp
JLF40_RS24600	COG3039	Transposase
JLF40_RS24610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JLF40_RS24630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JLF40_RS24630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JLF40_RS24670	COG3039	Transposase
JLF40_RS24700	COG2801	Transposase and inactivated derivatives
JLF40_RS24725	COG2801	Transposase and inactivated derivatives
JLF40_RS24730	COG0431	NADPH-dependent FMN reductase
JLF40_RS24735	COG0640	Transcriptional regulator
JLF40_RS24740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JLF40_RS24745	COG1393	Belongs to the ArsC family
JLF40_RS24750	COG0589	response to stress
JLF40_RS24755	COG0659	secondary active sulfate transmembrane transporter activity
JLF40_RS24830	COG2205	protein histidine kinase activity
JLF40_RS24840	COG2194	sulfuric ester hydrolase activity
JLF40_RS24905	COG2890	protein-(glutamine-N5) methyltransferase activity
JLF40_RS24970	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JLF40_RS25015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS25035	COG2199	diguanylate cyclase activity
JLF40_RS25055	COG0840	transmembrane signaling receptor activity
JLF40_RS25075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JLF40_RS25165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JLF40_RS25170	COG0501	Belongs to the peptidase M48B family
JLF40_RS25230	COG0542	response to heat
JLF40_RS25235	COG0071	Belongs to the small heat shock protein (HSP20) family
JLF40_RS25260	COG3039	Transposase
JLF40_RS25270	COG2205	protein histidine kinase activity
JLF40_RS25275	COG0745	RESPONSE REGULATOR receiver
JLF40_RS25280	COG1276	copper resistance
JLF40_RS25285	COG2372	response to copper ion
JLF40_RS25290	COG3667	copper resistance
JLF40_RS25295	COG2132	Multicopper oxidase
JLF40_RS25305	COG0739	heme binding
JLF40_RS25335	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JLF40_RS25465	COG2814	Major facilitator Superfamily
JLF40_RS25490	COG4974	Belongs to the 'phage' integrase family
JLF40_RS25575	COG1475	DNA binding
JLF40_RS25605	COG2801	Transposase and inactivated derivatives
JLF40_RS25620	COG3077	Addiction module antitoxin, RelB DinJ family
JLF40_RS25625	COG2026	Addiction module toxin, RelE StbE family
JLF40_RS25630	COG3328	transposase activity
JLF40_RS25660	COG3328	transposase activity
JLF40_RS25705	COG4974	Belongs to the 'phage' integrase family
JLF40_RS25730	COG4245	von Willebrand factor, type A
JLF40_RS25765	COG1358	cellular component organization or biogenesis