locus-tag	class	description
H1D58_RS00035	COG1358	cellular component organization or biogenesis
H1D58_RS00065	COG4245	von Willebrand factor, type A
H1D58_RS00070	COG4245	von Willebrand factor, type A
H1D58_RS00095	COG4974	Belongs to the 'phage' integrase family
H1D58_RS00115	COG1595	DNA-templated transcription, initiation
H1D58_RS00120	COG3712	iron ion homeostasis
H1D58_RS00125	COG4772	TonB-dependent receptor
H1D58_RS00130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H1D58_RS00135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS00140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS00145	COG1120	ATPase activity
H1D58_RS00150	COG3436	PFAM IS66 Orf2 family protein
H1D58_RS00170	COG1609	Transcriptional regulator
H1D58_RS00180	COG2223	nitrite transmembrane transporter activity
H1D58_RS00425	COG0640	Transcriptional regulator
H1D58_RS00430	COG0431	NADPH-dependent FMN reductase
H1D58_RS00465	COG1475	DNA binding
H1D58_RS00600	COG0071	Belongs to the small heat shock protein (HSP20) family
H1D58_RS00605	COG0542	response to heat
H1D58_RS00655	COG0501	Belongs to the peptidase M48B family
H1D58_RS00660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D58_RS00680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1D58_RS00685	COG1127	ABC transporter
H1D58_RS00735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H1D58_RS00740	COG3842	ATPase activity
H1D58_RS00745	COG0395	ABC-type sugar transport system, permease component
H1D58_RS00755	COG3039	Transposase
H1D58_RS00760	COG2135	peptidase activity
H1D58_RS00785	COG2814	Major facilitator Superfamily
H1D58_RS00835	COG2814	Major facilitator Superfamily
H1D58_RS00840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1D58_RS00850	COG3842	ATPase activity
H1D58_RS00860	COG1349	DNA-binding transcription factor activity
H1D58_RS00955	COG2948	multi-organism process
H1D58_RS00960	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
H1D58_RS00985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1D58_RS01020	COG3344	reverse transcriptase
H1D58_RS01130	COG4644	lycopene metabolic process
H1D58_RS01180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D58_RS01225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D58_RS01230	COG3118	belongs to the thioredoxin family
H1D58_RS01235	COG1902	pentaerythritol trinitrate reductase activity
H1D58_RS01240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1D58_RS01265	COG2372	response to copper ion
H1D58_RS01270	COG1276	copper resistance
H1D58_RS01275	COG0745	RESPONSE REGULATOR receiver
H1D58_RS01280	COG2205	protein histidine kinase activity
H1D58_RS01420	COG4213	ABC transporter substrate-binding protein
H1D58_RS01430	COG4214	carbohydrate transport
H1D58_RS01435	COG2207	Transcriptional regulator
H1D58_RS01435	COG1609	Transcriptional regulator
H1D58_RS01440	COG2992	FlgJ-related protein
H1D58_RS01445	COG0366	Alpha amylase catalytic
H1D58_RS01450	COG3977	Valine--pyruvate aminotransferase
H1D58_RS01455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D58_RS01460	COG1414	Transcriptional regulator
H1D58_RS01470	COG2731	YhcH YjgK YiaL family protein
H1D58_RS01480	COG2271	Major facilitator Superfamily
H1D58_RS01485	COG1070	Carbohydrate kinase
H1D58_RS01490	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H1D58_RS01495	COG3623	hexulose-6-phosphate isomerase
H1D58_RS01500	COG0235	Class ii aldolase
H1D58_RS01510	COG2211	Major facilitator Superfamily
H1D58_RS01520	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS01525	COG1940	carbohydrate kinase activity
H1D58_RS01530	COG3276	selenocysteine insertion sequence binding
H1D58_RS01540	COG0625	glutathione transferase activity
H1D58_RS01545	COG2213	PTS system mannitol-specific
H1D58_RS01545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS01555	COG3722	fumarate hydratase activity
H1D58_RS01570	COG3188	usher protein
H1D58_RS01575	COG3121	Chaperone
H1D58_RS01580	COG3539	Fimbrial protein
H1D58_RS01590	COG2186	Transcriptional regulator
H1D58_RS01595	COG1304	FMN binding
H1D58_RS01600	COG2271	Major facilitator Superfamily
H1D58_RS01605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1D58_RS01615	COG0583	DNA-binding transcription factor activity
H1D58_RS01620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1D58_RS01630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1D58_RS01635	COG3978	acetolactate synthase activity
H1D58_RS01655	COG3085	chromosome segregation
H1D58_RS01705	COG4206	TonB-dependent receptor
H1D58_RS01710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1D58_RS01730	COG0583	DNA-binding transcription factor activity
H1D58_RS01735	COG0165	Argininosuccinate lyase
H1D58_RS01745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H1D58_RS01750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1D58_RS01755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H1D58_RS01760	COG2207	Transcriptional regulator
H1D58_RS01770	COG0371	Dehydrogenase
H1D58_RS01775	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H1D58_RS01780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1D58_RS01785	COG0527	aspartate kinase activity
H1D58_RS01785	COG0460	homoserine dehydrogenase
H1D58_RS01790	COG0626	cystathionine gamma-synthase activity
H1D58_RS01800	COG0254	rRNA binding
H1D58_RS01805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1D58_RS01810	COG1609	Transcriptional regulator
H1D58_RS01815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1D58_RS01830	COG1575	Belongs to the MenA family. Type 1 subfamily
H1D58_RS01840	COG3074	FtsZ-dependent cytokinesis
H1D58_RS01845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1D58_RS01850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1D58_RS01855	COG1494	fructose-1,6-bisphosphatase
H1D58_RS01865	COG3152	Membrane
H1D58_RS01875	COG0149	triose-phosphate isomerase activity
H1D58_RS01885	COG2134	cdp-diacylglycerol pyrophosphatase
H1D58_RS01895	COG0205	6-phosphofructokinase activity
H1D58_RS01905	COG3678	ATP-independent chaperone mediated protein folding
H1D58_RS01910	COG0745	RESPONSE REGULATOR receiver
H1D58_RS01915	COG2205	protein histidine kinase activity
H1D58_RS01920	COG2258	MOSC domain
H1D58_RS01925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1D58_RS01935	COG1917	Cupin 2, conserved barrel domain protein
H1D58_RS01935	COG4977	sequence-specific DNA binding
H1D58_RS01940	COG4977	sequence-specific DNA binding
H1D58_RS01945	COG1070	Carbohydrate kinase
H1D58_RS01950	COG4806	L-rhamnose isomerase
H1D58_RS01955	COG0235	Class ii aldolase
H1D58_RS01965	COG1129	ABC transporter
H1D58_RS01970	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS01980	COG1454	alcohol dehydrogenase
H1D58_RS01985	COG3254	rhamnose metabolic process
H1D58_RS01990	COG3121	Chaperone
H1D58_RS02000	COG3188	usher protein
H1D58_RS02025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1D58_RS02050	COG0437	4 iron, 4 sulfur cluster binding
H1D58_RS02055	COG2864	formate dehydrogenase
H1D58_RS02060	COG3058	Necessary for formate dehydrogenase activity
H1D58_RS02070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1D58_RS02080	COG0456	acetyltransferase
H1D58_RS02095	COG1011	Hydrolase
H1D58_RS02100	COG1349	DNA-binding transcription factor activity
H1D58_RS02105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS02115	COG3684	Belongs to the aldolase LacD family
H1D58_RS02125	COG1501	Belongs to the glycosyl hydrolase 31 family
H1D58_RS02140	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1D58_RS02155	COG3852	Histidine kinase
H1D58_RS02170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1D58_RS02175	COG3078	GTPase activator activity
H1D58_RS02190	COG0204	Acyl-transferase
H1D58_RS02200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1D58_RS02205	COG3084	Protein conserved in bacteria
H1D58_RS02210	COG0746	molybdenum cofactor guanylyltransferase activity
H1D58_RS02215	COG1763	Mo-molybdopterin cofactor biosynthetic process
H1D58_RS02240	COG2186	Transcriptional regulator
H1D58_RS02245	COG0477	Major facilitator Superfamily
H1D58_RS02250	COG1609	Transcriptional regulator
H1D58_RS02255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS02265	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS02270	COG1129	ABC transporter
H1D58_RS02275	COG1869	D-ribose catabolic process
H1D58_RS02280	COG3158	transport of potassium into the cell
H1D58_RS02290	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H1D58_RS02295	COG2502	aspartate--ammonia ligase
H1D58_RS02300	COG1522	sequence-specific DNA binding
H1D58_RS02305	COG0716	FMN binding
H1D58_RS02310	COG0445	tRNA wobble uridine modification
H1D58_RS02315	COG0357	Ribosomal RNA small subunit methyltransferase G
H1D58_RS02320	COG3312	ion transport
H1D58_RS02325	COG0356	it plays a direct role in the translocation of protons across the membrane
H1D58_RS02335	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H1D58_RS02340	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H1D58_RS02345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H1D58_RS02355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H1D58_RS02360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H1D58_RS02365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H1D58_RS02375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1D58_RS02380	COG0573	inorganic phosphate transmembrane transporter activity
H1D58_RS02385	COG0581	inorganic phosphate transmembrane transporter activity
H1D58_RS02390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1D58_RS02395	COG0704	Plays a role in the regulation of phosphate uptake
H1D58_RS02400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D58_RS02405	COG2252	PERMEase
H1D58_RS02410	COG0431	NADPH-dependent FMN reductase
H1D58_RS02415	COG2091	lysine biosynthetic process via aminoadipic acid
H1D58_RS02435	COG0706	membrane insertase activity
H1D58_RS02460	COG0592	DNA-directed DNA polymerase activity
H1D58_RS02465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H1D58_RS02475	COG0583	DNA-binding transcription factor activity
H1D58_RS02485	COG0561	phosphatase activity
H1D58_RS02490	COG2186	Transcriptional regulator
H1D58_RS02495	COG3734	2-keto-3-deoxy-galactonokinase
H1D58_RS02500	COG0800	Aldolase
H1D58_RS02505	COG4948	Mandelate Racemase Muconate Lactonizing
H1D58_RS02510	COG2271	Major facilitator Superfamily
H1D58_RS02515	COG0823	Involved in the tonB-independent uptake of proteins
H1D58_RS02520	COG5645	(Lipo)protein
H1D58_RS02530	COG0071	Belongs to the small heat shock protein (HSP20) family
H1D58_RS02535	COG2985	domain, Protein
H1D58_RS02540	COG2188	Transcriptional regulator
H1D58_RS02555	COG2149	membrane
H1D58_RS02575	COG2814	Major facilitator Superfamily
H1D58_RS02610	COG0028	Belongs to the TPP enzyme family
H1D58_RS02615	COG0440	acetolactate synthase activity
H1D58_RS02620	COG2197	response regulator
H1D58_RS02640	COG0596	Alpha beta hydrolase
H1D58_RS02655	COG0697	spore germination
H1D58_RS02660	COG4580	involved in the transport of maltose and maltodextrins
H1D58_RS02665	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1D58_RS02670	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS02675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS02675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS02685	COG1609	Transcriptional regulator
H1D58_RS02700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS02705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS02715	COG0454	-acetyltransferase
H1D58_RS02720	COG1309	transcriptional regulator
H1D58_RS02730	COG1464	Belongs to the NlpA lipoprotein family
H1D58_RS02755	COG3188	usher protein
H1D58_RS02760	COG3121	Chaperone
H1D58_RS02790	COG3188	usher protein
H1D58_RS02815	COG2274	protein secretion by the type I secretion system
H1D58_RS02850	COG3272	Protein of unknown function (DUF1722)
H1D58_RS02860	COG0789	Transcriptional regulator
H1D58_RS02885	COG3121	Chaperone
H1D58_RS02940	COG2211	Major facilitator Superfamily
H1D58_RS02945	COG1501	Belongs to the glycosyl hydrolase 31 family
H1D58_RS02950	COG2982	Protein involved in outer membrane biogenesis
H1D58_RS02955	COG2233	PERMEase
H1D58_RS02960	COG0786	glutamate:sodium symporter activity
H1D58_RS02965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1D58_RS02970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1D58_RS02975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1D58_RS02990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H1D58_RS02995	COG2860	membrane
H1D58_RS03000	COG1561	YicC-like family, N-terminal region
H1D58_RS03010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H1D58_RS03020	COG0756	dUTP diphosphatase activity
H1D58_RS03025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1D58_RS03030	COG2003	Belongs to the UPF0758 family
H1D58_RS03035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H1D58_RS03040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H1D58_RS03045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1D58_RS03050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H1D58_RS03060	COG1519	Transferase
H1D58_RS03065	COG1216	Glycosyl transferase, family 2
H1D58_RS03070	COG0438	transferase activity, transferring glycosyl groups
H1D58_RS03080	COG0859	PFAM glycosyl transferase family 9
H1D58_RS03105	COG0859	PFAM glycosyl transferase family 9
H1D58_RS03110	COG0859	PFAM glycosyl transferase family 9
H1D58_RS03125	COG1063	alcohol dehydrogenase
H1D58_RS03140	COG0463	Glycosyl transferase, family 2
H1D58_RS03145	COG2861	carbohydrate metabolic process
H1D58_RS03150	COG4942	peptidase
H1D58_RS03155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1D58_RS03160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1D58_RS03165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1D58_RS03170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H1D58_RS03175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H1D58_RS03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1D58_RS03195	COG0248	Ppx GppA phosphatase
H1D58_RS03205	COG3118	belongs to the thioredoxin family
H1D58_RS03210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H1D58_RS03215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1D58_RS03225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H1D58_RS03230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1D58_RS03235	COG0456	acetyltransferase
H1D58_RS03240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1D58_RS03245	COG2244	polysaccharide biosynthetic process
H1D58_RS03260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H1D58_RS03290	COG3071	HemY protein
H1D58_RS03295	COG2959	enzyme of heme biosynthesis
H1D58_RS03305	COG0181	hydroxymethylbilane synthase activity
H1D58_RS03340	COG1011	Hydrolase
H1D58_RS03345	COG0210	DNA helicase
H1D58_RS03365	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H1D58_RS03375	COG1280	lysine exporter protein (LysE YggA)
H1D58_RS03380	COG1280	lysine exporter protein (LysE YggA)
H1D58_RS03385	COG2267	carboxylic ester hydrolase activity
H1D58_RS03390	COG0561	phosphatase activity
H1D58_RS03395	COG0697	spore germination
H1D58_RS03400	COG0583	DNA-binding transcription factor activity
H1D58_RS03410	COG0412	Dienelactone hydrolase
H1D58_RS03420	COG1322	Protein conserved in bacteria
H1D58_RS03425	COG2226	methyltransferase
H1D58_RS03430	COG3165	ubiquinone biosynthetic process from chorismate
H1D58_RS03435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1D58_RS03450	COG0805	protein transport
H1D58_RS03455	COG0084	hydrolase, TatD family'
H1D58_RS03465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1D58_RS03475	COG0488	(ABC) transporter
H1D58_RS03480	COG2944	sequence-specific DNA binding
H1D58_RS03490	COG1278	Cold shock
H1D58_RS03495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1D58_RS03505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS03515	COG1609	Transcriptional regulator
H1D58_RS03520	COG2885	chlorophyll binding
H1D58_RS03525	COG0243	molybdopterin cofactor binding
H1D58_RS03530	COG0456	acetyltransferase
H1D58_RS03535	COG2818	Glycosylase
H1D58_RS03540	COG5571	outer membrane autotransporter
H1D58_RS03545	COG2223	nitrite transmembrane transporter activity
H1D58_RS03560	COG0747	negative chemotaxis
H1D58_RS03565	COG0601	transmembrane transport
H1D58_RS03570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1D58_RS03575	COG0444	Belongs to the ABC transporter superfamily
H1D58_RS03580	COG4608	Belongs to the ABC transporter superfamily
H1D58_RS03585	COG1072	(Pantothenic acid kinase))
H1D58_RS03620	COG0250	Participates in transcription elongation, termination and antitermination
H1D58_RS03665	COG3706	GGDEF domain
H1D58_RS03675	COG2022	thiamine diphosphate biosynthetic process
H1D58_RS03680	COG2104	thiamine diphosphate biosynthetic process
H1D58_RS03685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1D58_RS03700	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H1D58_RS03710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H1D58_RS03715	COG1515	deoxyribonuclease V activity
H1D58_RS03735	COG0151	Belongs to the GarS family
H1D58_RS03765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1D58_RS03775	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
H1D58_RS03805	COG1187	pseudouridine synthase activity
H1D58_RS03820	COG0527	aspartate kinase activity
H1D58_RS03845	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1D58_RS03850	COG3223	Belongs to the PsiE family
H1D58_RS03885	COG3161	chorismate lyase activity
H1D58_RS03895	COG2937	Belongs to the GPAT DAPAT family
H1D58_RS03900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1D58_RS03905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1D58_RS03910	COG0534	Mate efflux family protein
H1D58_RS03915	COG3237	CsbD-like
H1D58_RS03920	COG0735	belongs to the Fur family
H1D58_RS03935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1D58_RS03945	COG0604	alcohol dehydrogenase
H1D58_RS03950	COG0305	Participates in initiation and elongation during chromosome replication
H1D58_RS03965	COG3172	ATPase kinase involved in NAD metabolism
H1D58_RS03965	COG1056	cytidyltransferase-related domain
H1D58_RS03970	COG1448	Aminotransferase
H1D58_RS03975	COG3700	Belongs to the class B bacterial acid phosphatase family
H1D58_RS03985	COG2315	Protein conserved in bacteria
H1D58_RS03995	COG0629	single-stranded DNA binding
H1D58_RS04010	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1D58_RS04020	COG0789	Transcriptional regulator
H1D58_RS04025	COG0625	glutathione transferase activity
H1D58_RS04030	COG2252	PERMEase
H1D58_RS04035	COG0025	NhaP-type Na H and K H
H1D58_RS04040	COG0583	DNA-binding transcription factor activity
H1D58_RS04050	COG1346	cytolysis
H1D58_RS04055	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1D58_RS04060	COG3162	membrane
H1D58_RS04070	COG1301	dicarboxylic acid transport
H1D58_RS04075	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1D58_RS04095	COG0745	RESPONSE REGULATOR receiver
H1D58_RS04105	COG0191	fructose-bisphosphate aldolase activity
H1D58_RS04120	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS04125	COG1129	ABC transporter
H1D58_RS04140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1D58_RS04145	COG0456	acetyltransferase
H1D58_RS04150	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H1D58_RS04155	COG3454	Phosphonate metabolism
H1D58_RS04160	COG4778	phosphonate C-P lyase system protein PhnL
H1D58_RS04165	COG4107	phosphonate C-P lyase system protein PhnK
H1D58_RS04170	COG3627	carbon phosphorus lyase activity
H1D58_RS04175	COG3626	phosphonate metabolism
H1D58_RS04180	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H1D58_RS04185	COG3624	Phosphonate C-P lyase system protein PhnG
H1D58_RS04190	COG2188	Transcriptional regulator
H1D58_RS04195	COG3639	organic phosphonate transmembrane transporter activity
H1D58_RS04200	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H1D58_RS04210	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H1D58_RS04215	COG2824	Alkylphosphonate utilization operon protein PhnA
H1D58_RS04220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H1D58_RS04240	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H1D58_RS04280	COG1309	transcriptional regulator
H1D58_RS04295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1D58_RS04300	COG1027	Aspartate ammonia-lyase
H1D58_RS04305	COG3030	protein affecting phage T7 exclusion by the F plasmid
H1D58_RS04310	COG0531	amino acid
H1D58_RS04320	COG0459	protein refolding
H1D58_RS04325	COG0700	Nucleoside recognition
H1D58_RS04330	COG3366	ferrous iron transmembrane transporter activity
H1D58_RS04355	COG5510	response to toxic substance
H1D58_RS04380	COG0583	DNA-binding transcription factor activity
H1D58_RS04390	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H1D58_RS04395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1D58_RS04400	COG1053	succinate dehydrogenase
H1D58_RS04405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1D58_RS04415	COG1511	domain protein
H1D58_RS04415	COG3264	Mechanosensitive ion channel
H1D58_RS04450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1D58_RS04455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1D58_RS04455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1D58_RS04460	COG0802	atpase or kinase
H1D58_RS04470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1D58_RS04475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H1D58_RS04480	COG1923	regulation of RNA biosynthetic process
H1D58_RS04485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1D58_RS04490	COG0330	HflC and HflK could
H1D58_RS04495	COG0330	HflC and HflK could
H1D58_RS04500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H1D58_RS04510	COG1959	2 iron, 2 sulfur cluster binding
H1D58_RS04515	COG0557	exoribonuclease II activity
H1D58_RS04520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1D58_RS04525	COG0477	Major facilitator Superfamily
H1D58_RS04530	COG1960	acyl-CoA dehydrogenase activity
H1D58_RS04545	COG3650	response to hydrogen peroxide
H1D58_RS04550	COG1073	alpha beta
H1D58_RS04565	COG3037	sugar-specific permease SgaT UlaA
H1D58_RS04605	COG2965	DNA replication, synthesis of RNA primer
H1D58_RS04610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H1D58_RS04615	COG0359	binds to the 23S rRNA
H1D58_RS04620	COG0697	spore germination
H1D58_RS04625	COG3061	Opacity-associated protein A
H1D58_RS04630	COG0545	Peptidyl-prolyl cis-trans isomerase
H1D58_RS04635	COG1113	amino acid transport
H1D58_RS04645	COG0840	transmembrane signaling receptor activity
H1D58_RS04650	COG0697	spore germination
H1D58_RS04660	COG0702	epimerase
H1D58_RS04665	COG1733	regulation of RNA biosynthetic process
H1D58_RS04675	COG1218	3'(2'),5'-bisphosphate nucleotidase
H1D58_RS04680	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H1D58_RS04690	COG1253	flavin adenine dinucleotide binding
H1D58_RS04695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H1D58_RS04700	COG0729	surface antigen
H1D58_RS04705	COG2911	Protein conserved in bacteria
H1D58_RS04710	COG2105	PFAM AIG2 family protein
H1D58_RS04720	COG1879	ABC-type sugar transport system periplasmic component
H1D58_RS04725	COG1129	ABC transporter
H1D58_RS04730	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS04735	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS04750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1D58_RS04755	COG3028	Belongs to the UPF0307 family
H1D58_RS04760	COG0312	modulator of DNA gyrase
H1D58_RS04795	COG3964	amidohydrolase
H1D58_RS04815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS04815	COG3711	transcriptional antiterminator
H1D58_RS04820	COG0602	queuosine metabolic process
H1D58_RS04830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS04830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS04830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS04835	COG0383	alpha-mannosidase activity
H1D58_RS04855	COG0366	Alpha amylase catalytic
H1D58_RS04860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS04860	COG1263	PTS System
H1D58_RS04875	COG1609	Transcriptional regulator
H1D58_RS04885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H1D58_RS04890	COG3397	chitin binding
H1D58_RS04895	COG0251	oxidation-reduction process
H1D58_RS04905	COG0540	Belongs to the ATCase OTCase family
H1D58_RS04920	COG1438	arginine binding
H1D58_RS04925	COG1288	antiporter activity
H1D58_RS04940	COG2235	arginine
H1D58_RS04945	COG2731	YhcH YjgK YiaL family protein
H1D58_RS04950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1D58_RS04955	COG0129	dihydroxy-acid dehydratase activity
H1D58_RS04960	COG2211	Major facilitator Superfamily
H1D58_RS04965	COG3507	Belongs to the glycosyl hydrolase 43 family
H1D58_RS04970	COG1414	Transcriptional regulator
H1D58_RS04975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1D58_RS05090	COG1609	Transcriptional regulator
H1D58_RS05100	COG2211	Major facilitator Superfamily
H1D58_RS05125	COG1335	isochorismatase
H1D58_RS05140	COG2204	response regulator
H1D58_RS05145	COG4191	Histidine kinase
H1D58_RS05150	COG4566	intracellular signal transduction
H1D58_RS05155	COG0740	serine-type endopeptidase activity
H1D58_RS05160	COG2850	peptidyl-arginine hydroxylation
H1D58_RS05185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D58_RS05190	COG5457	Domain of unknown function (DUF1127)
H1D58_RS05200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D58_RS05215	COG0640	Transcriptional regulator
H1D58_RS05235	COG2733	membrane
H1D58_RS05245	COG1917	Cupin 2, conserved barrel domain protein
H1D58_RS05245	COG2207	Transcriptional regulator
H1D58_RS05250	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS05270	COG0523	cobalamin synthesis protein
H1D58_RS05275	COG2879	small protein
H1D58_RS05280	COG1966	Carbon starvation protein
H1D58_RS05285	COG1349	DNA-binding transcription factor activity
H1D58_RS05290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D58_RS05295	COG2368	4-hydroxyphenylacetate
H1D58_RS05315	COG3971	2-oxopent-4-enoate hydratase activity
H1D58_RS05325	COG3384	dioxygenase
H1D58_RS05330	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS05335	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1D58_RS05340	COG1846	Transcriptional regulator
H1D58_RS05345	COG0840	transmembrane signaling receptor activity
H1D58_RS05365	COG1484	DNA-dependent DNA replication
H1D58_RS05375	COG1764	response to oxidative stress
H1D58_RS05380	COG1846	Transcriptional regulator
H1D58_RS05385	COG3610	response to peptide
H1D58_RS05390	COG2966	Psort location CytoplasmicMembrane, score
H1D58_RS05395	COG2197	response regulator
H1D58_RS05400	COG2197	response regulator
H1D58_RS05405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1D58_RS05410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS05415	COG4114	ferric iron reductase
H1D58_RS05420	COG3706	GGDEF domain
H1D58_RS05445	COG2813	Specifically methylates the guanine in position
H1D58_RS05450	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H1D58_RS05455	COG0456	acetyltransferase
H1D58_RS05460	COG1011	Hydrolase
H1D58_RS05465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1D58_RS05470	COG2823	Periplasmic or secreted lipoprotein
H1D58_RS05475	COG5487	UPF0391 membrane protein
H1D58_RS05480	COG4667	esterase of the alpha-beta hydrolase superfamily
H1D58_RS05485	COG0084	hydrolase, TatD family'
H1D58_RS05490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1D58_RS05495	COG1328	CTP reductase activity
H1D58_RS05505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H1D58_RS05525	COG3726	membrane protein affecting hemolysin expression
H1D58_RS05530	COG0560	Phosphoserine phosphatase
H1D58_RS05555	COG0488	(ABC) transporter
H1D58_RS05560	COG0741	lytic transglycosylase activity
H1D58_RS05565	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
H1D58_RS05570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
H1D58_RS05575	COG0406	alpha-ribazole phosphatase activity
H1D58_RS05580	COG3708	Transcriptional regulator
H1D58_RS05580	COG2207	Transcriptional regulator
H1D58_RS05585	COG3045	CreA protein
H1D58_RS05590	COG0745	RESPONSE REGULATOR receiver
H1D58_RS05600	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H1D58_RS05610	COG0527	aspartate kinase activity
H1D58_RS05610	COG0460	homoserine dehydrogenase
H1D58_RS05620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1D58_RS05635	COG1115	amino acid carrier protein
H1D58_RS05645	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1D58_RS05650	COG0477	Major facilitator Superfamily
H1D58_RS05655	COG1584	GPR1 FUN34 yaaH family protein
H1D58_RS05660	COG0443	Heat shock 70 kDa protein
H1D58_RS05670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1D58_RS05675	COG0583	DNA-binding transcription factor activity
H1D58_RS05680	COG0268	Binds directly to 16S ribosomal RNA
H1D58_RS05685	COG0196	riboflavin kinase activity
H1D58_RS05700	COG1047	Peptidyl-prolyl cis-trans
H1D58_RS05705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H1D58_RS05715	COG0505	Belongs to the CarA family
H1D58_RS05740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1D58_RS05740	COG0475	glutathione-regulated potassium exporter activity
H1D58_RS05750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1D58_RS05755	COG2967	ApaG domain
H1D58_RS05765	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H1D58_RS05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1D58_RS05775	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1D58_RS05780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1D58_RS05785	COG0564	pseudouridine synthase activity
H1D58_RS05795	COG0417	DNA replication proofreading
H1D58_RS05800	COG0235	Class ii aldolase
H1D58_RS05805	COG2160	L-arabinose isomerase activity
H1D58_RS05810	COG1069	ribulokinase activity
H1D58_RS05820	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS05830	COG1178	ABC-type Fe3 transport system permease component
H1D58_RS05850	COG2814	Major facilitator Superfamily
H1D58_RS05875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1D58_RS05890	COG0028	Belongs to the TPP enzyme family
H1D58_RS05900	COG1609	Transcriptional regulator
H1D58_RS05905	COG2001	Belongs to the MraZ family
H1D58_RS05920	COG0768	penicillin binding
H1D58_RS05925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1D58_RS05930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1D58_RS05935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1D58_RS05945	COG0772	Belongs to the SEDS family
H1D58_RS05960	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1D58_RS05970	COG0849	cell division
H1D58_RS05975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1D58_RS05980	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H1D58_RS05990	COG0653	protein targeting
H1D58_RS05995	COG0494	nUDIX hydrolase
H1D58_RS06000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1D58_RS06005	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H1D58_RS06015	COG0516	GMP reductase activity
H1D58_RS06020	COG1459	type II secretion system
H1D58_RS06025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1D58_RS06030	COG4969	Belongs to the N-Me-Phe pilin family
H1D58_RS06040	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1D58_RS06045	COG3725	Membrane protein required for beta-lactamase induction
H1D58_RS06050	COG3940	Belongs to the glycosyl hydrolase 43 family
H1D58_RS06055	COG2211	Major facilitator Superfamily
H1D58_RS06060	COG1113	amino acid transport
H1D58_RS06065	COG2186	Transcriptional regulator
H1D58_RS06070	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H1D58_RS06075	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1D58_RS06080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1D58_RS06090	COG3064	Membrane
H1D58_RS06105	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H1D58_RS06110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H1D58_RS06120	COG2132	Multicopper oxidase
H1D58_RS06125	COG4993	Dehydrogenase
H1D58_RS06145	COG3561	AntA/AntB antirepressor
H1D58_RS06235	COG4626	Terminase
H1D58_RS06235	COG1802	Transcriptional regulator
H1D58_RS06255	COG0288	reversible hydration of carbon dioxide
H1D58_RS06260	COG1131	(ABC) transporter
H1D58_RS06265	COG0842	Transport permease protein
H1D58_RS06270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS06275	COG0726	polysaccharide deacetylase
H1D58_RS06285	COG3539	Fimbrial protein
H1D58_RS06295	COG3539	Fimbrial protein
H1D58_RS06300	COG3188	usher protein
H1D58_RS06305	COG3121	Chaperone
H1D58_RS06315	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H1D58_RS06320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H1D58_RS06330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1D58_RS06335	COG0617	tRNA 3'-terminal CCA addition
H1D58_RS06340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1D58_RS06350	COG1489	DNA binding
H1D58_RS06355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H1D58_RS06360	COG1643	Atp-dependent helicase
H1D58_RS06365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1D58_RS06370	COG4774	siderophore transport
H1D58_RS06375	COG1120	ATPase activity
H1D58_RS06380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1D58_RS06385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS06390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H1D58_RS06400	COG0316	Belongs to the HesB IscA family
H1D58_RS06405	COG2860	membrane
H1D58_RS06415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1D58_RS06420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H1D58_RS06425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D58_RS06430	COG3835	regulator
H1D58_RS06475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H1D58_RS06485	COG0575	Belongs to the CDS family
H1D58_RS06490	COG0750	zinc metalloprotease
H1D58_RS06495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1D58_RS06510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H1D58_RS06515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D58_RS06520	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D58_RS06525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1D58_RS06535	COG0825	malonyl-CoA metabolic process
H1D58_RS06545	COG0346	lactoylglutathione lyase activity
H1D58_RS06550	COG0037	tRNA processing
H1D58_RS06555	COG4568	rho-dependent transcription termination
H1D58_RS06570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H1D58_RS06575	COG3015	lipoprotein NlpE involved in copper resistance
H1D58_RS06585	COG1720	tRNA m6t6A37 methyltransferase activity
H1D58_RS06595	COG1464	Belongs to the NlpA lipoprotein family
H1D58_RS06600	COG2011	ABC-type metal ion transport system permease component
H1D58_RS06610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1D58_RS06655	COG2814	Major facilitator Superfamily
H1D58_RS06660	COG3021	interspecies interaction between organisms
H1D58_RS06665	COG2226	methyltransferase
H1D58_RS06670	COG0741	lytic transglycosylase activity
H1D58_RS06670	COG1388	LysM domain
H1D58_RS06675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D58_RS06680	COG2226	methyltransferase
H1D58_RS06705	COG0444	Belongs to the ABC transporter superfamily
H1D58_RS06710	COG4608	Belongs to the ABC transporter superfamily
H1D58_RS06735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1D58_RS06740	COG1960	acyl-CoA dehydrogenase activity
H1D58_RS06750	COG0121	glutamine amidotransferase
H1D58_RS06755	COG3034	peptidoglycan biosynthetic process
H1D58_RS06770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H1D58_RS06775	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H1D58_RS06790	COG2991	Protein conserved in bacteria
H1D58_RS06795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1D58_RS06800	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1D58_RS06820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1D58_RS06825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H1D58_RS06830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H1D58_RS06870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1D58_RS06900	COG0628	permease
H1D58_RS06905	COG0833	amino acid
H1D58_RS06910	COG2040	homocysteine
H1D58_RS06915	COG4521	taurine ABC transporter
H1D58_RS06920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1D58_RS06925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1D58_RS06930	COG2175	clavaminate synthase activity
H1D58_RS06940	COG0113	porphobilinogen synthase activity
H1D58_RS06955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1D58_RS06960	COG1335	isochorismatase
H1D58_RS06965	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1D58_RS06985	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1D58_RS07010	COG3706	GGDEF domain
H1D58_RS07015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1D58_RS07020	COG1671	Belongs to the UPF0178 family
H1D58_RS07025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1D58_RS07035	COG4126	flavin adenine dinucleotide binding
H1D58_RS07040	COG3123	guanosine phosphorylase activity
H1D58_RS07050	COG1940	carbohydrate kinase activity
H1D58_RS07055	COG0419	ATPase involved in DNA repair
H1D58_RS07060	COG0420	3'-5' exonuclease activity
H1D58_RS07070	COG5002	protein histidine kinase activity
H1D58_RS07085	COG0366	Alpha amylase catalytic
H1D58_RS07100	COG0450	alkyl hydroperoxide reductase
H1D58_RS07105	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
H1D58_RS07120	COG1862	Preprotein translocase
H1D58_RS07125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1D58_RS07130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1D58_RS07145	COG4238	major outer membrane lipoprotein
H1D58_RS07150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H1D58_RS07155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1D58_RS07155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1D58_RS07160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H1D58_RS07165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1D58_RS07170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1D58_RS07175	COG0667	Aldo Keto reductase
H1D58_RS07180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1D58_RS07185	COG0142	geranyltranstransferase activity
H1D58_RS07200	COG0693	protein deglycase activity
H1D58_RS07215	COG2814	Major facilitator Superfamily
H1D58_RS07220	COG0235	Class ii aldolase
H1D58_RS07230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1D58_RS07240	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS07245	COG1129	ABC transporter
H1D58_RS07255	COG1070	Carbohydrate kinase
H1D58_RS07265	COG0109	protoheme IX farnesyltransferase activity
H1D58_RS07270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1D58_RS07275	COG1845	cytochrome c oxidase, subunit III
H1D58_RS07280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1D58_RS07285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1D58_RS07290	COG2223	nitrite transmembrane transporter activity
H1D58_RS07295	COG3056	Lipoprotein
H1D58_RS07300	COG0271	Belongs to the BolA IbaG family
H1D58_RS07305	COG0544	peptidyl-prolyl cis-trans isomerase activity
H1D58_RS07320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1D58_RS07325	COG0776	regulation of translation
H1D58_RS07330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1D58_RS07335	COG1555	photosystem II stabilization
H1D58_RS07340	COG0824	Thioesterase
H1D58_RS07345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1D58_RS07350	COG4533	DNA binding
H1D58_RS07355	COG0561	phosphatase activity
H1D58_RS07365	COG1522	sequence-specific DNA binding
H1D58_RS07370	COG1132	(ABC) transporter
H1D58_RS07375	COG1132	(ABC) transporter
H1D58_RS07380	COG0347	Belongs to the P(II) protein family
H1D58_RS07385	COG0004	ammonium transporteR
H1D58_RS07390	COG1946	Acyl-CoA thioesterase
H1D58_RS07395	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H1D58_RS07400	COG3695	enzyme binding
H1D58_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D58_RS07425	COG2364	Membrane
H1D58_RS07430	COG1609	Transcriptional regulator
H1D58_RS07440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1D58_RS07450	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H1D58_RS07470	COG0110	maltose O-acetyltransferase activity
H1D58_RS07485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS07495	COG1309	transcriptional regulator
H1D58_RS07500	COG1196	nuclear chromosome segregation
H1D58_RS07500	COG3264	Mechanosensitive ion channel
H1D58_RS07510	COG3923	Primosomal replication protein n
H1D58_RS07515	COG2832	Protein of unknown function (DUF454)
H1D58_RS07520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1D58_RS07530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H1D58_RS07535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1D58_RS07540	COG0326	Molecular chaperone. Has ATPase activity
H1D58_RS07550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H1D58_RS07555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS07560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1D58_RS07560	COG4651	solute:proton antiporter activity
H1D58_RS07565	COG2223	nitrite transmembrane transporter activity
H1D58_RS07575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1D58_RS07580	COG3735	TraB family
H1D58_RS07585	COG2217	Heavy metal translocating P-type atpase
H1D58_RS07595	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1D58_RS07600	COG0330	HflC and HflK could
H1D58_RS07610	COG4619	ABC transporter
H1D58_RS07615	COG0390	transport system, permease component
H1D58_RS07620	COG3118	belongs to the thioredoxin family
H1D58_RS07625	COG0300	oxidoreductase activity
H1D58_RS07630	COG2755	lipolytic protein G-D-S-L family
H1D58_RS07635	COG4181	ATPase activity
H1D58_RS07640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1D58_RS07655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1D58_RS07660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1D58_RS07665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D58_RS07670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1D58_RS07680	COG1988	membrane-bound metal-dependent
H1D58_RS07685	COG1609	Transcriptional regulator
H1D58_RS07690	COG2190	(PTS) system
H1D58_RS07690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS07690	COG1263	PTS System
H1D58_RS07695	COG2501	S4 domain
H1D58_RS07800	COG2246	polysaccharide biosynthetic process
H1D58_RS07820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1D58_RS07845	COG1113	amino acid transport
H1D58_RS07850	COG2211	Major facilitator Superfamily
H1D58_RS07865	COG1609	Transcriptional regulator
H1D58_RS07870	COG0668	transmembrane transport
H1D58_RS07875	COG0477	Major facilitator Superfamily
H1D58_RS07890	COG0778	Nitroreductase
H1D58_RS07895	COG2315	Protein conserved in bacteria
H1D58_RS07910	COG2207	Transcriptional regulator
H1D58_RS07915	COG4774	siderophore transport
H1D58_RS07945	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H1D58_RS07960	COG3209	COG3209 Rhs family protein
H1D58_RS07975	COG4680	protein conserved in bacteria
H1D58_RS07990	COG1278	Cold shock
H1D58_RS08040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D58_RS08045	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H1D58_RS08060	COG1121	(ABC) transporter
H1D58_RS08065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1D58_RS08070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1D58_RS08075	COG2977	Belongs to the P-Pant transferase superfamily
H1D58_RS08080	COG4771	TonB-dependent receptor
H1D58_RS08085	COG2382	esterase
H1D58_RS08090	COG3251	PFAM MbtH domain protein
H1D58_RS08095	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1D58_RS08095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1D58_RS08100	COG1120	ATPase activity
H1D58_RS08105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS08110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS08120	COG4592	Periplasmic binding protein
H1D58_RS08125	COG1169	isochorismate synthase
H1D58_RS08130	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1D58_RS08135	COG3433	isochorismatase activity
H1D58_RS08135	COG1535	isochorismatase
H1D58_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS08145	COG2050	protein possibly involved in aromatic compounds catabolism
H1D58_RS08155	COG0700	Nucleoside recognition
H1D58_RS08160	COG3366	ferrous iron transmembrane transporter activity
H1D58_RS08165	COG1966	Carbon starvation protein
H1D58_RS08170	COG2879	small protein
H1D58_RS08190	COG0371	Dehydrogenase
H1D58_RS08195	COG1129	ABC transporter
H1D58_RS08200	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS08215	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H1D58_RS08230	COG3423	Transcriptional regulator
H1D58_RS08245	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
H1D58_RS08250	COG0235	Class ii aldolase
H1D58_RS08255	COG0436	Aminotransferase
H1D58_RS08260	COG1475	DNA binding
H1D58_RS08265	COG3969	phosphoadenosine phosphosulfate
H1D58_RS08270	COG0583	DNA-binding transcription factor activity
H1D58_RS08290	COG1063	alcohol dehydrogenase
H1D58_RS08295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1D58_RS08305	COG3719	Belongs to the RNase T2 family
H1D58_RS08310	COG3069	C4-dicarboxylate transmembrane transporter activity
H1D58_RS08330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS08335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS08355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1D58_RS08360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1D58_RS08365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1D58_RS08370	COG0583	DNA-binding transcription factor activity
H1D58_RS08375	COG0321	lipoyl(octanoyl) transferase activity
H1D58_RS08385	COG1686	Belongs to the peptidase S11 family
H1D58_RS08390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1D58_RS08395	COG0772	Belongs to the SEDS family
H1D58_RS08400	COG0768	penicillin binding
H1D58_RS08410	COG0799	negative regulation of ribosome biogenesis
H1D58_RS08420	COG1466	dna polymerase III delta subunit
H1D58_RS08435	COG2888	peptidyl-tyrosine sulfation
H1D58_RS08440	COG1957	nucleoside hydrolase
H1D58_RS08445	COG1126	abc transporter atp-binding protein
H1D58_RS08450	COG0765	amino acid transport
H1D58_RS08455	COG0765	amino acid transport
H1D58_RS08475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H1D58_RS08480	COG1702	phosphate starvation-inducible protein PhoH
H1D58_RS08485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H1D58_RS08490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D58_RS08530	COG0367	asparagine synthase
H1D58_RS08535	COG0647	UMP catabolic process
H1D58_RS08540	COG1846	Transcriptional regulator
H1D58_RS08540	COG1940	carbohydrate kinase activity
H1D58_RS08545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1D58_RS08555	COG1263	PTS System
H1D58_RS08555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS08555	COG2190	(PTS) system
H1D58_RS08560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1D58_RS08575	COG0735	belongs to the Fur family
H1D58_RS08595	COG0596	Alpha beta hydrolase
H1D58_RS08600	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H1D58_RS08605	COG0033	Phosphoglucomutase
H1D58_RS08610	COG0531	amino acid
H1D58_RS08615	COG1982	Orn Lys Arg decarboxylase major
H1D58_RS08625	COG0745	RESPONSE REGULATOR receiver
H1D58_RS08630	COG2205	protein histidine kinase activity
H1D58_RS08635	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H1D58_RS08640	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1D58_RS08645	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1D58_RS08665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1D58_RS08670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H1D58_RS08675	COG1984	allophanate hydrolase subunit 2
H1D58_RS08685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1D58_RS08690	COG0372	Belongs to the citrate synthase family
H1D58_RS08695	COG2009	succinate dehydrogenase
H1D58_RS08700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1D58_RS08705	COG1053	succinate dehydrogenase
H1D58_RS08710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1D58_RS08715	COG0567	Dehydrogenase, E1 component
H1D58_RS08720	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1D58_RS08725	COG0045	succinate-CoA ligase (ADP-forming) activity
H1D58_RS08730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1D58_RS08735	COG2188	Transcriptional regulator
H1D58_RS08740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS08740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS08740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS08745	COG0383	alpha-mannosidase activity
H1D58_RS08750	COG1271	oxidase subunit
H1D58_RS08755	COG1294	oxidase, subunit
H1D58_RS08760	COG4890	Cyd operon protein YbgT
H1D58_RS08765	COG3790	cyd operon protein YbgE
H1D58_RS08770	COG0824	Thioesterase
H1D58_RS08775	COG0811	peptide transport
H1D58_RS08780	COG0848	biopolymer transport protein
H1D58_RS08785	COG3064	Membrane
H1D58_RS08790	COG0823	Involved in the tonB-independent uptake of proteins
H1D58_RS08795	COG2885	chlorophyll binding
H1D58_RS08800	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H1D58_RS08835	COG3201	nicotinamide mononucleotide transporter
H1D58_RS08840	COG1230	cation diffusion facilitator family transporter
H1D58_RS08850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1D58_RS08860	COG2017	converts alpha-aldose to the beta-anomer
H1D58_RS08865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H1D58_RS08870	COG1085	galactose-1-phosphate uridylyltransferase
H1D58_RS08875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1D58_RS08880	COG1119	ATPase activity
H1D58_RS08885	COG3585	molybdate ion transport
H1D58_RS08885	COG2005	Transcriptional regulator
H1D58_RS08895	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1D58_RS08900	COG4149	molybdate abc transporter
H1D58_RS08910	COG0561	phosphatase activity
H1D58_RS08915	COG2706	6-phosphogluconolactonase activity
H1D58_RS08920	COG4677	pectinesterase activity
H1D58_RS08930	COG0010	Belongs to the arginase family
H1D58_RS08940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H1D58_RS08945	COG2986	histidine ammonia-lyase
H1D58_RS08950	COG1881	PFAM PEBP family protein
H1D58_RS08955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1D58_RS08960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H1D58_RS08965	COG0156	8-amino-7-oxononanoate synthase activity
H1D58_RS08970	COG2226	methyltransferase
H1D58_RS09000	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1D58_RS09005	COG0315	cyclic pyranopterin monophosphate synthase activity
H1D58_RS09010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H1D58_RS09015	COG0314	molybdopterin synthase activity
H1D58_RS09020	COG0670	Belongs to the BI1 family
H1D58_RS09025	COG0392	lysyltransferase activity
H1D58_RS09030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1D58_RS09035	COG3568	Endonuclease Exonuclease Phosphatase
H1D58_RS09045	COG0842	Transport permease protein
H1D58_RS09050	COG0842	Transport permease protein
H1D58_RS09055	COG1131	(ABC) transporter
H1D58_RS09060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS09065	COG1309	transcriptional regulator
H1D58_RS09070	COG0513	Belongs to the DEAD box helicase family
H1D58_RS09100	COG3539	Fimbrial protein
H1D58_RS09105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1D58_RS09115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1D58_RS09125	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H1D58_RS09130	COG0668	transmembrane transport
H1D58_RS09135	COG1126	abc transporter atp-binding protein
H1D58_RS09140	COG0765	amino acid transport
H1D58_RS09145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D58_RS09150	COG0783	Belongs to the Dps family
H1D58_RS09160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1D58_RS09165	COG2194	sulfuric ester hydrolase activity
H1D58_RS09175	COG1321	iron dependent repressor
H1D58_RS09180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1D58_RS09185	COG1566	PFAM secretion protein HlyD family protein
H1D58_RS09190	COG2814	Major facilitator Superfamily
H1D58_RS09200	COG0667	Aldo Keto reductase
H1D58_RS09205	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS09210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS09215	COG2188	Transcriptional regulator
H1D58_RS09220	COG1376	ErfK ybiS ycfS ynhG family protein
H1D58_RS09225	COG0488	(ABC) transporter
H1D58_RS09235	COG2271	Major facilitator Superfamily
H1D58_RS09240	COG1609	Transcriptional regulator
H1D58_RS09250	COG0561	phosphatase activity
H1D58_RS09255	COG1882	Formate acetyltransferase
H1D58_RS09260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1D58_RS09265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1D58_RS09275	COG0303	'Molybdopterin
H1D58_RS09280	COG1446	asparaginase
H1D58_RS09315	COG2133	pyrroloquinoline quinone binding
H1D58_RS09320	COG0625	glutathione transferase activity
H1D58_RS09325	COG1686	Belongs to the peptidase S11 family
H1D58_RS09330	COG1349	DNA-binding transcription factor activity
H1D58_RS09335	COG0671	phosphoesterase, PA-phosphatase related
H1D58_RS09345	COG2814	Major facilitator Superfamily
H1D58_RS09350	COG0561	phosphatase activity
H1D58_RS09355	COG0738	Major facilitator superfamily
H1D58_RS09360	COG3226	Transcriptional regulator
H1D58_RS09365	COG1393	Belongs to the ArsC family
H1D58_RS09370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1D58_RS09375	COG0640	Transcriptional regulator
H1D58_RS09405	COG0778	Nitroreductase
H1D58_RS09420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1D58_RS09425	COG3842	ATPase activity
H1D58_RS09430	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1D58_RS09435	COG1177	transmembrane transport
H1D58_RS09445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1D58_RS09450	COG0745	RESPONSE REGULATOR receiver
H1D58_RS09455	COG5002	protein histidine kinase activity
H1D58_RS09460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D58_RS09465	COG4160	amino acid transport
H1D58_RS09470	COG4215	(ABC) transporter
H1D58_RS09475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D58_RS09480	COG1126	abc transporter atp-binding protein
H1D58_RS09490	COG0393	Putative heavy-metal-binding
H1D58_RS09495	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1D58_RS09515	COG3031	protein transport across the cell outer membrane
H1D58_RS09520	COG1450	Type ii and iii secretion system protein
H1D58_RS09525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1D58_RS09530	COG1459	type II secretion system
H1D58_RS09535	COG2165	general secretion pathway protein
H1D58_RS09545	COG2165	general secretion pathway protein
H1D58_RS09570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H1D58_RS09585	COG3397	chitin binding
H1D58_RS09590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1D58_RS09595	COG0702	epimerase
H1D58_RS09600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H1D58_RS09605	COG0028	Belongs to the TPP enzyme family
H1D58_RS09610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D58_RS09615	COG1151	hydroxylamine reductase activity
H1D58_RS09620	COG2431	L-lysine efflux transmembrane transporter activity
H1D58_RS09630	COG3593	DNA synthesis involved in DNA repair
H1D58_RS09635	COG2990	Protein conserved in bacteria
H1D58_RS09640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS09650	COG1278	Cold shock
H1D58_RS09655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1D58_RS09660	COG0542	response to heat
H1D58_RS09670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H1D58_RS09675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1D58_RS09680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H1D58_RS09685	COG4988	ABC transporter
H1D58_RS09690	COG0492	ferredoxin-NADP+ reductase activity
H1D58_RS09700	COG1178	ABC-type Fe3 transport system permease component
H1D58_RS09700	COG1674	ftsk spoiiie
H1D58_RS09705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1D58_RS09710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1D58_RS09715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H1D58_RS09720	COG0243	molybdopterin cofactor binding
H1D58_RS09725	COG0437	4 iron, 4 sulfur cluster binding
H1D58_RS09730	COG3302	dmso reductase anchor subunit
H1D58_RS09735	COG0477	Major facilitator Superfamily
H1D58_RS09745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1D58_RS09750	COG1882	Formate acetyltransferase
H1D58_RS09755	COG2116	formate transmembrane transporter activity
H1D58_RS09760	COG1944	ATP diphosphatase activity
H1D58_RS09765	COG2323	membrane
H1D58_RS09770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H1D58_RS09775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1D58_RS09780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H1D58_RS09785	COG0539	negative regulation of cytoplasmic translation
H1D58_RS09790	COG0776	regulation of translation
H1D58_RS09795	COG2333	competence protein COMEC
H1D58_RS09795	COG0658	competence protein
H1D58_RS09800	COG1132	(ABC) transporter
H1D58_RS09810	COG3214	Protein conserved in bacteria
H1D58_RS09815	COG2835	tetraacyldisaccharide 4'-kinase activity
H1D58_RS09820	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H1D58_RS09825	COG3173	Aminoglycoside phosphotransferase
H1D58_RS09830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1D58_RS09835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1D58_RS09845	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H1D58_RS09850	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H1D58_RS09855	COG2989	Protein conserved in bacteria
H1D58_RS09860	COG3108	Peptidase M15
H1D58_RS09865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D58_RS09870	COG1448	Aminotransferase
H1D58_RS09880	COG0017	Asparaginyl-tRNA synthetase
H1D58_RS09885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H1D58_RS09890	COG0308	aminopeptidase N
H1D58_RS09900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1D58_RS09905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS09910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1D58_RS09915	COG0431	NADPH-dependent FMN reductase
H1D58_RS09920	COG0167	dihydroorotate dehydrogenase activity
H1D58_RS09930	COG0633	Ferredoxin
H1D58_RS09930	COG3217	Mosc domain protein beta barrel domain protein
H1D58_RS09935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H1D58_RS09935	COG0116	Belongs to the methyltransferase superfamily
H1D58_RS09940	COG0488	(ABC) transporter
H1D58_RS09945	COG2995	paraquat-inducible protein a
H1D58_RS09950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1D58_RS09950	COG3008	intermembrane lipid transfer
H1D58_RS09955	COG3009	Protein conserved in bacteria
H1D58_RS09960	COG3130	regulation of translation
H1D58_RS09970	COG1067	ATP-dependent peptidase activity
H1D58_RS09975	COG3120	sequence-specific DNA binding
H1D58_RS09985	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
H1D58_RS09990	COG3070	regulator of competence-specific genes
H1D58_RS09995	COG1289	transmembrane transporter activity
H1D58_RS10000	COG3304	Inner membrane component domain
H1D58_RS10005	COG0210	DNA helicase
H1D58_RS10010	COG1803	Methylglyoxal synthase
H1D58_RS10015	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1D58_RS10020	COG1832	CoA-binding protein
H1D58_RS10030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H1D58_RS10035	COG1254	Belongs to the acylphosphatase family
H1D58_RS10045	COG0670	Belongs to the BI1 family
H1D58_RS10065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS10075	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H1D58_RS10075	COG3264	Mechanosensitive ion channel
H1D58_RS10095	COG2239	Acts as a magnesium transporter
H1D58_RS10100	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS10120	COG3729	General stress protein
H1D58_RS10130	COG2233	PERMEase
H1D58_RS10135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D58_RS10140	COG0778	Nitroreductase
H1D58_RS10145	COG2267	carboxylic ester hydrolase activity
H1D58_RS10150	COG0251	oxidation-reduction process
H1D58_RS10155	COG1335	isochorismatase
H1D58_RS10160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS10165	COG1309	transcriptional regulator
H1D58_RS10175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1D58_RS10175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1D58_RS10175	COG0506	proline dehydrogenase activity
H1D58_RS10180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1D58_RS10190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1D58_RS10210	COG1702	phosphate starvation-inducible protein PhoH
H1D58_RS10215	COG1115	amino acid carrier protein
H1D58_RS10230	COG1335	isochorismatase
H1D58_RS10240	COG0583	DNA-binding transcription factor activity
H1D58_RS10255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1D58_RS10260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H1D58_RS10265	COG3381	protein complex oligomerization
H1D58_RS10315	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H1D58_RS10330	COG2943	transferase activity, transferring hexosyl groups
H1D58_RS10335	COG5645	(Lipo)protein
H1D58_RS10350	COG1560	Kdo2-lipid A biosynthetic process
H1D58_RS10360	COG2353	YceI-like domain
H1D58_RS10365	COG3038	cytochrome b561
H1D58_RS10390	COG0418	dihydroorotase activity
H1D58_RS10400	COG0477	Major facilitator Superfamily
H1D58_RS10405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS10410	COG3132	Protein of unknown function, DUF480
H1D58_RS10445	COG1558	bacterial-type flagellum-dependent cell motility
H1D58_RS10455	COG1749	Flagellar hook protein flgE
H1D58_RS10465	COG4786	Flagellar basal body rod
H1D58_RS10485	COG1256	bacterial-type flagellum assembly
H1D58_RS10495	COG2814	Major facilitator Superfamily
H1D58_RS10500	COG0583	DNA-binding transcription factor activity
H1D58_RS10505	COG1530	ribonuclease E activity
H1D58_RS10515	COG0424	maF-like protein
H1D58_RS10525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H1D58_RS10530	COG0416	fatty acid biosynthetic process
H1D58_RS10535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1D58_RS10550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1D58_RS10555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1D58_RS10560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1D58_RS10565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1D58_RS10575	COG0470	DNA polymerase III
H1D58_RS10580	COG0084	hydrolase, TatD family'
H1D58_RS10590	COG4773	Receptor
H1D58_RS10595	COG0537	adenosine 5'-monophosphoramidase activity
H1D58_RS10600	COG5633	Lipoprotein
H1D58_RS10605	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
H1D58_RS10620	COG3150	esterase
H1D58_RS10625	COG1252	NADH dehydrogenase
H1D58_RS10630	COG3134	Outer membrane lipoprotein
H1D58_RS10635	COG1309	transcriptional regulator
H1D58_RS10645	COG1388	LysM domain
H1D58_RS10645	COG1376	ErfK ybiS ycfS ynhG family protein
H1D58_RS10650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1D58_RS10655	COG4763	Acyl-transferase
H1D58_RS10660	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1D58_RS10665	COG1136	(ABC) transporter
H1D58_RS10670	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1D58_RS10710	COG1943	Transposase
H1D58_RS10715	COG2850	peptidyl-arginine hydroxylation
H1D58_RS10720	COG2205	protein histidine kinase activity
H1D58_RS10735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1D58_RS10740	COG2915	High frequency lysogenization protein hflD homolog
H1D58_RS10755	COG1187	pseudouridine synthase activity
H1D58_RS10760	COG0538	isocitrate dehydrogenase activity
H1D58_RS10770	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1D58_RS10780	COG2261	transglycosylase associated protein
H1D58_RS10795	COG2203	Gaf domain
H1D58_RS10795	COG2199	diguanylate cyclase activity
H1D58_RS10800	COG3042	response to heat
H1D58_RS10810	COG3189	MarR family transcriptional regulator
H1D58_RS10815	COG0504	CTP synthase activity
H1D58_RS10820	COG2807	transmembrane transport
H1D58_RS10825	COG2207	Transcriptional regulator
H1D58_RS10830	COG2707	UPF0756 membrane protein
H1D58_RS10840	COG2211	Major facilitator Superfamily
H1D58_RS10845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1D58_RS10850	COG2718	Belongs to the UPF0229 family
H1D58_RS10855	COG2766	serine protein kinase
H1D58_RS10860	COG3713	MltA-interacting MipA family protein
H1D58_RS10880	COG3139	Protein of unknown function (DUF1315)
H1D58_RS10890	COG1335	isochorismatase
H1D58_RS10895	COG0252	asparaginase activity
H1D58_RS10900	COG0616	signal peptide processing
H1D58_RS10905	COG0778	Nitroreductase
H1D58_RS10910	COG0709	Synthesizes selenophosphate from selenide and ATP
H1D58_RS10915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1D58_RS10930	COG0494	nUDIX hydrolase
H1D58_RS10935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D58_RS10940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1D58_RS10945	COG2897	thiosulfate sulfurtransferase activity
H1D58_RS10950	COG4136	ATPase activity
H1D58_RS10955	COG4135	transport system, permease component
H1D58_RS10960	COG4134	Bacterial extracellular solute-binding protein
H1D58_RS10980	COG3138	arginine N-succinyltransferase
H1D58_RS10985	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS10990	COG3724	N-succinylarginine dihydrolase activity
H1D58_RS11000	COG3678	ATP-independent chaperone mediated protein folding
H1D58_RS11010	COG0322	excinuclease ABC activity
H1D58_RS11015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1D58_RS11020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1D58_RS11025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS11030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS11035	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1D58_RS11040	COG1917	Cupin 2, conserved barrel domain protein
H1D58_RS11040	COG2169	Transcriptional regulator
H1D58_RS11045	COG1486	melibiose metabolic process
H1D58_RS11050	COG3394	polysaccharide catabolic process
H1D58_RS11055	COG0753	catalase activity
H1D58_RS11070	COG1988	membrane-bound metal-dependent
H1D58_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS11080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D58_RS11090	COG3001	Fructosamine kinase
H1D58_RS11100	COG1105	Belongs to the carbohydrate kinase PfkB family
H1D58_RS11110	COG3137	Salt-induced outer membrane protein
H1D58_RS11155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H1D58_RS11160	COG0072	phenylalanine-tRNA ligase activity
H1D58_RS11160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1D58_RS11165	COG0776	regulation of translation
H1D58_RS11175	COG0386	Belongs to the glutathione peroxidase family
H1D58_RS11185	COG0791	NLP P60 protein
H1D58_RS11195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1D58_RS11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS11210	COG4558	Periplasmic binding protein
H1D58_RS11215	COG3720	iron ion transport
H1D58_RS11225	COG4256	Hemin uptake protein
H1D58_RS11230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1D58_RS11235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H1D58_RS11240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1D58_RS11240	COG0574	Belongs to the PEP-utilizing enzyme family
H1D58_RS11245	COG2211	Major facilitator Superfamily
H1D58_RS11250	COG1472	Belongs to the glycosyl hydrolase 3 family
H1D58_RS11265	COG0628	permease
H1D58_RS11270	COG0247	lactate metabolic process
H1D58_RS11270	COG0277	FAD linked oxidase domain protein
H1D58_RS11275	COG2050	protein possibly involved in aromatic compounds catabolism
H1D58_RS11285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1D58_RS11345	COG2200	EAL domain
H1D58_RS11350	COG0789	Transcriptional regulator
H1D58_RS11365	COG0316	Belongs to the HesB IscA family
H1D58_RS11370	COG0719	Fe-S assembly protein
H1D58_RS11375	COG0396	ATPase activity
H1D58_RS11380	COG0719	Fe-S assembly protein
H1D58_RS11385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1D58_RS11390	COG2166	iron-sulfur cluster assembly
H1D58_RS11395	COG1376	ErfK ybiS ycfS ynhG family protein
H1D58_RS11410	COG0626	cystathionine gamma-synthase activity
H1D58_RS11425	COG2011	ABC-type metal ion transport system permease component
H1D58_RS11430	COG1464	Belongs to the NlpA lipoprotein family
H1D58_RS11455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D58_RS11465	COG4529	Protein conserved in bacteria
H1D58_RS11480	COG0534	Mate efflux family protein
H1D58_RS11485	COG0307	riboflavin synthase, alpha
H1D58_RS11490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1D58_RS11495	COG2814	Major facilitator Superfamily
H1D58_RS11500	COG0583	DNA-binding transcription factor activity
H1D58_RS11515	COG2814	Major facilitator Superfamily
H1D58_RS11525	COG0791	NLP P60 protein
H1D58_RS11530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1D58_RS11540	COG0346	lactoylglutathione lyase activity
H1D58_RS11545	COG1902	pentaerythritol trinitrate reductase activity
H1D58_RS11550	COG1309	transcriptional regulator
H1D58_RS11555	COG2194	sulfuric ester hydrolase activity
H1D58_RS11560	COG3313	Fe-S protein
H1D58_RS11565	COG4989	oxidoreductase activity
H1D58_RS11570	COG2032	superoxide dismutase activity
H1D58_RS11575	COG1289	transmembrane transporter activity
H1D58_RS11580	COG1566	PFAM secretion protein HlyD family protein
H1D58_RS11595	COG3706	GGDEF domain
H1D58_RS11605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1D58_RS11610	COG3895	Periplasmic Protein
H1D58_RS11615	COG0259	pyridoxamine-phosphate oxidase activity
H1D58_RS11620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1D58_RS11625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H1D58_RS11630	COG0625	glutathione transferase activity
H1D58_RS11635	COG3104	oligopeptide transport
H1D58_RS11640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1D58_RS11690	COG0673	inositol 2-dehydrogenase activity
H1D58_RS11695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1D58_RS11700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1D58_RS11705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS11705	COG1263	PTS System
H1D58_RS11710	COG1609	Transcriptional regulator
H1D58_RS11715	COG5339	Protein conserved in bacteria
H1D58_RS11725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D58_RS11725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D58_RS11740	COG2205	protein histidine kinase activity
H1D58_RS11750	COG0745	RESPONSE REGULATOR receiver
H1D58_RS11755	COG3136	membrane protein required for alginate biosynthesis
H1D58_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS11765	COG0531	amino acid
H1D58_RS11775	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H1D58_RS11780	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H1D58_RS11785	COG0668	transmembrane transport
H1D58_RS11790	COG0589	response to stress
H1D58_RS11800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1D58_RS11805	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H1D58_RS11810	COG1473	amidohydrolase
H1D58_RS11820	COG0583	DNA-binding transcription factor activity
H1D58_RS11825	COG2840	Smr protein MutS2
H1D58_RS11835	COG0667	Aldo Keto reductase
H1D58_RS11890	COG1403	HNH endonuclease
H1D58_RS11895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS11905	COG0628	permease
H1D58_RS11910	COG2076	Multidrug Resistance protein
H1D58_RS11915	COG2076	Multidrug Resistance protein
H1D58_RS11920	COG3591	Belongs to the peptidase S1B family
H1D58_RS11935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H1D58_RS11940	COG2814	Major facilitator Superfamily
H1D58_RS11945	COG0583	DNA-binding transcription factor activity
H1D58_RS11950	COG1940	carbohydrate kinase activity
H1D58_RS11955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H1D58_RS12005	COG3141	response to X-ray
H1D58_RS12010	COG3381	protein complex oligomerization
H1D58_RS12015	COG3302	dmso reductase anchor subunit
H1D58_RS12020	COG0437	4 iron, 4 sulfur cluster binding
H1D58_RS12025	COG0243	molybdopterin cofactor binding
H1D58_RS12045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS12060	COG4948	Mandelate Racemase Muconate Lactonizing
H1D58_RS12065	COG1063	alcohol dehydrogenase
H1D58_RS12070	COG0477	Major facilitator Superfamily
H1D58_RS12075	COG0246	Mannitol dehydrogenase
H1D58_RS12085	COG0589	response to stress
H1D58_RS12090	COG1802	Transcriptional regulator
H1D58_RS12095	COG4221	oxidoreductase activity
H1D58_RS12110	COG1278	Cold shock
H1D58_RS12115	COG2135	peptidase activity
H1D58_RS12150	COG0598	Magnesium transport protein CorA
H1D58_RS12165	COG4993	Dehydrogenase
H1D58_RS12190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1D58_RS12195	COG2911	Protein conserved in bacteria
H1D58_RS12205	COG3784	Protein of unknown function (DUF1318)
H1D58_RS12210	COG2207	Transcriptional regulator
H1D58_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS12220	COG2203	Gaf domain
H1D58_RS12220	COG3706	GGDEF domain
H1D58_RS12220	COG4251	negative regulation of phosphorylation
H1D58_RS12220	COG5001	Diguanylate cyclase
H1D58_RS12225	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H1D58_RS12230	COG3733	amine oxidase
H1D58_RS12250	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS12250	COG2030	dehydratase
H1D58_RS12255	COG3396	Phenylacetate-CoA oxygenase
H1D58_RS12260	COG3460	Phenylacetate-CoA oxygenase
H1D58_RS12265	COG3396	Phenylacetate-CoA oxygenase
H1D58_RS12270	COG2151	metal-sulfur cluster biosynthetic enzyme
H1D58_RS12275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D58_RS12280	COG1024	Enoyl-CoA hydratase
H1D58_RS12285	COG1024	Enoyl-CoA hydratase
H1D58_RS12290	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D58_RS12295	COG2050	protein possibly involved in aromatic compounds catabolism
H1D58_RS12300	COG0183	Belongs to the thiolase family
H1D58_RS12305	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1D58_RS12310	COG3327	negative regulation of DNA-templated transcription, initiation
H1D58_RS12315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1D58_RS12320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D58_RS12330	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H1D58_RS12350	COG0300	oxidoreductase activity
H1D58_RS12365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1D58_RS12410	COG3122	Protein conserved in bacteria
H1D58_RS12415	COG0564	pseudouridine synthase activity
H1D58_RS12425	COG1643	Atp-dependent helicase
H1D58_RS12450	COG0477	Major facilitator Superfamily
H1D58_RS12455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1D58_RS12460	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS12465	COG3038	cytochrome b561
H1D58_RS12475	COG1349	DNA-binding transcription factor activity
H1D58_RS12490	COG2274	protein secretion by the type I secretion system
H1D58_RS12545	COG0840	transmembrane signaling receptor activity
H1D58_RS12550	COG0583	DNA-binding transcription factor activity
H1D58_RS12555	COG5383	Protein conserved in bacteria
H1D58_RS12560	COG2272	Belongs to the type-B carboxylesterase lipase family
H1D58_RS12570	COG0436	Aminotransferase
H1D58_RS12580	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
H1D58_RS12585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS12590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1D58_RS12595	COG1275	C4-dicarboxylate transporter malic acid transport protein
H1D58_RS12600	COG0500	methyltransferase
H1D58_RS12605	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1D58_RS12610	COG0747	negative chemotaxis
H1D58_RS12620	COG0697	spore germination
H1D58_RS12630	COG3135	benzoate transporter
H1D58_RS12635	COG1396	sequence-specific DNA binding
H1D58_RS12640	COG0826	peptidase U32
H1D58_RS12665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1D58_RS12685	COG1122	ATPase activity
H1D58_RS12695	COG3443	Belongs to the bacterial solute-binding protein 9 family
H1D58_RS12700	COG2814	Major facilitator Superfamily
H1D58_RS12705	COG0697	spore germination
H1D58_RS12720	COG1846	Transcriptional regulator
H1D58_RS12730	COG2814	Major facilitator Superfamily
H1D58_RS12750	COG0583	DNA-binding transcription factor activity
H1D58_RS12755	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS12765	COG2066	Belongs to the glutaminase family
H1D58_RS12775	COG3706	GGDEF domain
H1D58_RS12790	COG3781	membrane
H1D58_RS12825	COG0596	Alpha beta hydrolase
H1D58_RS12830	COG0745	RESPONSE REGULATOR receiver
H1D58_RS12835	COG2205	protein histidine kinase activity
H1D58_RS12850	COG0494	nUDIX hydrolase
H1D58_RS12855	COG1349	DNA-binding transcription factor activity
H1D58_RS12865	COG0659	secondary active sulfate transmembrane transporter activity
H1D58_RS12870	COG0589	response to stress
H1D58_RS12875	COG1393	Belongs to the ArsC family
H1D58_RS12880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1D58_RS12885	COG0640	Transcriptional regulator
H1D58_RS12890	COG0431	NADPH-dependent FMN reductase
H1D58_RS12895	COG2801	Transposase and inactivated derivatives
H1D58_RS12920	COG0583	DNA-binding transcription factor activity
H1D58_RS12925	COG2814	Major facilitator Superfamily
H1D58_RS12950	COG3121	Chaperone
H1D58_RS12965	COG3121	Chaperone
H1D58_RS13010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H1D58_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS13035	COG0583	DNA-binding transcription factor activity
H1D58_RS13040	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1D58_RS13045	COG4628	conserved protein (DUF2132)
H1D58_RS13055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D58_RS13070	COG0840	transmembrane signaling receptor activity
H1D58_RS13100	COG2200	EAL domain
H1D58_RS13115	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H1D58_RS13120	COG0747	negative chemotaxis
H1D58_RS13125	COG0601	transmembrane transport
H1D58_RS13130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1D58_RS13135	COG0444	Belongs to the ABC transporter superfamily
H1D58_RS13140	COG4608	Belongs to the ABC transporter superfamily
H1D58_RS13145	COG1764	response to oxidative stress
H1D58_RS13190	COG0281	malic enzyme
H1D58_RS13195	COG0488	(ABC) transporter
H1D58_RS13200	COG1064	alcohol dehydrogenase
H1D58_RS13210	COG1252	NADH dehydrogenase
H1D58_RS13215	COG2814	Major facilitator Superfamily
H1D58_RS13225	COG2864	formate dehydrogenase
H1D58_RS13230	COG0437	4 iron, 4 sulfur cluster binding
H1D58_RS13240	COG0697	spore germination
H1D58_RS13260	COG2223	nitrite transmembrane transporter activity
H1D58_RS13265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1D58_RS13270	COG1140	nitrate reductase beta subunit
H1D58_RS13275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1D58_RS13280	COG2181	nitrate reductase activity
H1D58_RS13285	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H1D58_RS13290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D58_RS13305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H1D58_RS13310	COG0640	Transcriptional regulator
H1D58_RS13315	COG0583	DNA-binding transcription factor activity
H1D58_RS13320	COG0456	acetyltransferase
H1D58_RS13330	COG1560	Kdo2-lipid A biosynthetic process
H1D58_RS13335	COG1942	4-Oxalocrotonate Tautomerase
H1D58_RS13340	COG0625	glutathione transferase activity
H1D58_RS13345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D58_RS13350	COG1126	abc transporter atp-binding protein
H1D58_RS13365	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H1D58_RS13370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS13375	COG1473	amidohydrolase
H1D58_RS13380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS13385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1D58_RS13410	COG4772	TonB-dependent receptor
H1D58_RS13415	COG1802	Transcriptional regulator
H1D58_RS13420	COG2130	NADP-dependent
H1D58_RS13430	COG1247	-acetyltransferase
H1D58_RS13435	COG3238	Protein conserved in bacteria
H1D58_RS13445	COG0747	negative chemotaxis
H1D58_RS13475	COG3615	Tellurite resistance protein tehB
H1D58_RS13480	COG3615	Tellurite resistance protein tehB
H1D58_RS13490	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS13495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D58_RS13505	COG1271	oxidase subunit
H1D58_RS13510	COG1294	oxidase, subunit
H1D58_RS13520	COG3187	Heat shock protein
H1D58_RS13525	COG3042	response to heat
H1D58_RS13530	COG0674	pyruvate-flavodoxin oxidoreductase activity
H1D58_RS13530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1D58_RS13530	COG1013	pyruvate-flavodoxin oxidoreductase activity
H1D58_RS13530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H1D58_RS13535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1D58_RS13550	COG0582	viral genome integration into host DNA
H1D58_RS13560	COG0513	Belongs to the DEAD box helicase family
H1D58_RS13575	COG0840	transmembrane signaling receptor activity
H1D58_RS13695	COG4166	transmembrane transport
H1D58_RS13700	COG2866	Carboxypeptidase
H1D58_RS13705	COG4948	Mandelate Racemase Muconate Lactonizing
H1D58_RS13710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H1D58_RS13720	COG3768	UPF0283 membrane protein
H1D58_RS13725	COG3106	COG3106 Predicted ATPase
H1D58_RS13730	COG1609	Transcriptional regulator
H1D58_RS13740	COG3842	ATPase activity
H1D58_RS13745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D58_RS13750	COG1554	hydrolase, family 65, central catalytic
H1D58_RS13755	COG0673	inositol 2-dehydrogenase activity
H1D58_RS13760	COG1082	Xylose isomerase domain protein TIM barrel
H1D58_RS13765	COG1063	alcohol dehydrogenase
H1D58_RS13770	COG0395	ABC-type sugar transport system, permease component
H1D58_RS13775	COG1175	transmembrane transport
H1D58_RS13780	COG1653	transport
H1D58_RS13785	COG0366	Alpha amylase catalytic
H1D58_RS13795	COG1983	PspC domain protein
H1D58_RS13805	COG1842	Phage shock protein A
H1D58_RS13810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1D58_RS13825	COG4171	peptide transport system, permease
H1D58_RS13835	COG4172	Belongs to the ABC transporter superfamily
H1D58_RS13840	COG1309	transcriptional regulator
H1D58_RS13845	COG0251	oxidation-reduction process
H1D58_RS13850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H1D58_RS13855	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D58_RS13855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D58_RS13860	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
H1D58_RS13865	COG5001	Diguanylate cyclase
H1D58_RS13870	COG1024	Enoyl-CoA hydratase
H1D58_RS13880	COG1349	DNA-binding transcription factor activity
H1D58_RS13890	COG0023	Translation Initiation Factor
H1D58_RS13895	COG0284	orotidine-5'-phosphate decarboxylase activity
H1D58_RS13900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H1D58_RS13905	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H1D58_RS13910	COG0671	phosphoesterase, PA-phosphatase related
H1D58_RS13920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1D58_RS13950	COG0616	signal peptide processing
H1D58_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS13960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H1D58_RS14040	COG0463	Glycosyl transferase, family 2
H1D58_RS14045	COG0009	L-threonylcarbamoyladenylate synthase
H1D58_RS14050	COG0613	PHP domain protein
H1D58_RS14065	COG0512	Glutamine amidotransferase of anthranilate synthase
H1D58_RS14065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1D58_RS14080	COG0159	tryptophan synthase activity
H1D58_RS14085	COG2391	methyltransferase activity
H1D58_RS14090	COG0425	Belongs to the sulfur carrier protein TusA family
H1D58_RS14095	COG3047	cAMP biosynthetic process
H1D58_RS14100	COG0727	PFAM Uncharacterised protein family (UPF0153)
H1D58_RS14130	COG2350	Protein conserved in bacteria
H1D58_RS14150	COG1280	lysine exporter protein (LysE YggA)
H1D58_RS14170	COG3099	Belongs to the UPF0263 family
H1D58_RS14175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1D58_RS14180	COG4608	Belongs to the ABC transporter superfamily
H1D58_RS14185	COG0444	Belongs to the ABC transporter superfamily
H1D58_RS14205	COG2095	MarC family integral membrane protein
H1D58_RS14210	COG1454	alcohol dehydrogenase
H1D58_RS14210	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS14215	COG1435	thymidine kinase activity
H1D58_RS14225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1D58_RS14230	COG0745	RESPONSE REGULATOR receiver
H1D58_RS14235	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1D58_RS14240	COG3012	SEC-C Motif Domain Protein
H1D58_RS14245	COG0788	formyltetrahydrofolate deformylase activity
H1D58_RS14260	COG2181	nitrate reductase activity
H1D58_RS14265	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1D58_RS14270	COG1140	nitrate reductase beta subunit
H1D58_RS14275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1D58_RS14280	COG2223	nitrite transmembrane transporter activity
H1D58_RS14285	COG3850	Histidine kinase
H1D58_RS14290	COG2197	response regulator
H1D58_RS14295	COG4932	domain protein
H1D58_RS14300	COG0243	molybdopterin cofactor binding
H1D58_RS14305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D58_RS14305	COG2146	nitrite reductase [NAD(P)H] activity
H1D58_RS14310	COG1116	anion transmembrane transporter activity
H1D58_RS14320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1D58_RS14325	COG3707	response regulator
H1D58_RS14330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1D58_RS14335	COG0840	transmembrane signaling receptor activity
H1D58_RS14345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H1D58_RS14350	COG4572	Cation transport regulator
H1D58_RS14355	COG0387	Pfam Sodium calcium exchanger
H1D58_RS14360	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H1D58_RS14375	COG2890	protein-(glutamine-N5) methyltransferase activity
H1D58_RS14385	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H1D58_RS14395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H1D58_RS14405	COG0659	secondary active sulfate transmembrane transporter activity
H1D58_RS14420	COG0193	aminoacyl-tRNA hydrolase activity
H1D58_RS14425	COG0012	GTP binding
H1D58_RS14450	COG5444	nuclease activity
H1D58_RS14475	COG3209	COG3209 Rhs family protein
H1D58_RS14490	COG3501	Rhs element vgr protein
H1D58_RS14510	COG0515	serine threonine protein kinase
H1D58_RS14630	COG4977	sequence-specific DNA binding
H1D58_RS14635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1D58_RS14645	COG4774	siderophore transport
H1D58_RS14655	COG0741	lytic transglycosylase activity
H1D58_RS14660	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1D58_RS14665	COG3263	regulation of cellular component size
H1D58_RS14670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1D58_RS14675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1D58_RS14680	COG2719	SpoVR family
H1D58_RS14690	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1D58_RS14700	COG2983	Belongs to the UPF0260 family
H1D58_RS14705	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1D58_RS14715	COG0850	regulation of cytokinetic process
H1D58_RS14720	COG2894	cell division
H1D58_RS14725	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H1D58_RS14730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H1D58_RS14735	COG0318	PFAM AMP-dependent synthetase and ligase
H1D58_RS14740	COG3065	identical protein binding
H1D58_RS14745	COG1214	PFAM Peptidase M22, glycoprotease
H1D58_RS14750	COG1199	ATP-dependent helicase activity
H1D58_RS14755	COG0251	oxidation-reduction process
H1D58_RS14760	COG3140	Belongs to the UPF0181 family
H1D58_RS14775	COG1760	l-serine dehydratase
H1D58_RS14780	COG2200	EAL domain
H1D58_RS14785	COG1253	flavin adenine dinucleotide binding
H1D58_RS14790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS14790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS14795	COG3715	PTS system
H1D58_RS14800	COG3716	PTS system mannose fructose sorbose family IID component
H1D58_RS14805	COG4811	Protein of unknown function (DUF986)
H1D58_RS14810	COG1971	Probably functions as a manganese efflux pump
H1D58_RS14815	COG2226	methyltransferase
H1D58_RS14820	COG0768	penicillin binding
H1D58_RS14850	COG1414	Transcriptional regulator
H1D58_RS14855	COG2814	Major facilitator Superfamily
H1D58_RS14860	COG0501	Belongs to the peptidase M48B family
H1D58_RS14870	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H1D58_RS14875	COG1956	GAF domain-containing protein
H1D58_RS14880	COG2995	paraquat-inducible protein a
H1D58_RS14885	COG3008	intermembrane lipid transfer
H1D58_RS14890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1D58_RS14890	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H1D58_RS14905	COG2990	Protein conserved in bacteria
H1D58_RS14920	COG1276	copper resistance
H1D58_RS14925	COG2372	response to copper ion
H1D58_RS14935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1D58_RS14940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1D58_RS14945	COG1770	oligopeptidase
H1D58_RS14950	COG2979	Protein of unknown function (DUF533)
H1D58_RS14990	COG0800	Aldolase
H1D58_RS14995	COG0129	dihydroxy-acid dehydratase activity
H1D58_RS15000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H1D58_RS15005	COG1737	Transcriptional regulator
H1D58_RS15015	COG1560	Kdo2-lipid A biosynthetic process
H1D58_RS15020	COG0739	heme binding
H1D58_RS15025	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H1D58_RS15035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1D58_RS15040	COG2255	four-way junction helicase activity
H1D58_RS15045	COG0632	four-way junction helicase activity
H1D58_RS15060	COG0494	nUDIX hydrolase
H1D58_RS15070	COG1335	isochorismatase
H1D58_RS15075	COG1801	Protein of unknown function DUF72
H1D58_RS15080	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H1D58_RS15085	COG2226	methyltransferase
H1D58_RS15095	COG3142	Participates in the control of copper homeostasis
H1D58_RS15100	COG3102	Protein conserved in bacteria
H1D58_RS15105	COG0018	arginyl-trna synthetase
H1D58_RS15120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H1D58_RS15150	COG0745	RESPONSE REGULATOR receiver
H1D58_RS15165	COG0840	transmembrane signaling receptor activity
H1D58_RS15200	COG1301	dicarboxylic acid transport
H1D58_RS15240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1D58_RS15250	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS15260	COG1879	ABC-type sugar transport system periplasmic component
H1D58_RS15270	COG1528	Iron-storage protein
H1D58_RS15275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1D58_RS15305	COG1528	Iron-storage protein
H1D58_RS15315	COG0814	amino acid
H1D58_RS15320	COG3012	SEC-C Motif Domain Protein
H1D58_RS15320	COG3318	Belongs to the UPF0149 family
H1D58_RS15355	COG0583	DNA-binding transcription factor activity
H1D58_RS15395	COG2197	response regulator
H1D58_RS15405	COG2197	response regulator
H1D58_RS15445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H1D58_RS15450	COG1516	flagellar protein fliS
H1D58_RS15460	COG0366	Alpha amylase catalytic
H1D58_RS15470	COG1677	Flagellar hook-basal body complex protein FliE
H1D58_RS15480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1D58_RS15490	COG1157	protein secretion by the type III secretion system
H1D58_RS15530	COG1987	bacterial-type flagellum assembly
H1D58_RS15540	COG2197	response regulator
H1D58_RS15565	COG5475	Uncharacterized small protein (DUF2158)
H1D58_RS15570	COG2354	Protein conserved in bacteria
H1D58_RS15575	COG0697	spore germination
H1D58_RS15580	COG3727	T/G mismatch-specific endonuclease activity
H1D58_RS15585	COG0270	DNA (cytosine-5-)-methyltransferase activity
H1D58_RS15590	COG1418	mRNA catabolic process
H1D58_RS15600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1D58_RS15610	COG3290	protein histidine kinase activity
H1D58_RS15615	COG4565	transcriptional regulatory protein
H1D58_RS15635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D58_RS15635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D58_RS15660	COG0583	DNA-binding transcription factor activity
H1D58_RS15720	COG1376	ErfK ybiS ycfS ynhG family protein
H1D58_RS15725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1D58_RS15730	COG0589	response to stress
H1D58_RS15740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS15755	COG0477	Major facilitator Superfamily
H1D58_RS15760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1D58_RS15765	COG0006	proline dipeptidase activity
H1D58_RS15775	COG0534	Mate efflux family protein
H1D58_RS15790	COG1289	transmembrane transporter activity
H1D58_RS15795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1D58_RS15805	COG2925	Exonuclease
H1D58_RS15810	COG0531	amino acid
H1D58_RS15820	COG0583	DNA-binding transcription factor activity
H1D58_RS15825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1D58_RS15835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1D58_RS15845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H1D58_RS15850	COG0131	Imidazoleglycerol-phosphate dehydratase
H1D58_RS15850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1D58_RS15855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1D58_RS15860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H1D58_RS15865	COG0107	imidazoleglycerol-phosphate synthase activity
H1D58_RS15910	COG3754	Rhamnan synthesis protein F
H1D58_RS15935	COG1091	dTDP-4-dehydrorhamnose reductase activity
H1D58_RS15955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1D58_RS15975	COG0438	transferase activity, transferring glycosyl groups
H1D58_RS15980	COG2327	Polysaccharide pyruvyl transferase
H1D58_RS15985	COG2244	polysaccharide biosynthetic process
H1D58_RS15990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1D58_RS15995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1D58_RS16005	COG0297	glycogen (starch) synthase activity
H1D58_RS16010	COG1051	belongs to the nudix hydrolase family
H1D58_RS16015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1D58_RS16020	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H1D58_RS16025	COG0110	maltose O-acetyltransferase activity
H1D58_RS16030	COG1216	Glycosyl transferase, family 2
H1D58_RS16040	COG0438	transferase activity, transferring glycosyl groups
H1D58_RS16045	COG1045	serine acetyltransferase
H1D58_RS16050	COG0463	Glycosyl transferase, family 2
H1D58_RS16055	COG3206	protein involved in exopolysaccharide biosynthesis
H1D58_RS16055	COG0489	protein tyrosine kinase activity
H1D58_RS16070	COG1253	flavin adenine dinucleotide binding
H1D58_RS16075	COG2982	Protein involved in outer membrane biogenesis
H1D58_RS16080	COG0717	Belongs to the dCTP deaminase family
H1D58_RS16090	COG3447	MASE1 domain protein
H1D58_RS16090	COG5001	Diguanylate cyclase
H1D58_RS16090	COG5002	protein histidine kinase activity
H1D58_RS16095	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H1D58_RS16100	COG0443	Heat shock 70 kDa protein
H1D58_RS16110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS16115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS16120	COG0477	Major facilitator Superfamily
H1D58_RS16125	COG2205	protein histidine kinase activity
H1D58_RS16130	COG0745	RESPONSE REGULATOR receiver
H1D58_RS16160	COG1597	lipid kinase activity
H1D58_RS16165	COG1830	Aldolase
H1D58_RS16170	COG2211	Major facilitator Superfamily
H1D58_RS16175	COG1397	ADP-ribosylglycohydrolase
H1D58_RS16180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS16185	COG2188	Transcriptional regulator
H1D58_RS16190	COG0351	phosphomethylpyrimidine kinase
H1D58_RS16195	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H1D58_RS16220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1D58_RS16225	COG0076	glutamate decarboxylase activity
H1D58_RS16230	COG0489	protein tyrosine kinase activity
H1D58_RS16230	COG3206	protein involved in exopolysaccharide biosynthesis
H1D58_RS16235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1D58_RS16240	COG1596	polysaccharide export
H1D58_RS16245	COG5455	response to cobalt ion
H1D58_RS16250	COG0456	acetyltransferase
H1D58_RS16255	COG0489	protein tyrosine kinase activity
H1D58_RS16265	COG4807	Protein conserved in bacteria
H1D58_RS16270	COG3279	Response regulator of the LytR AlgR family
H1D58_RS16275	COG3275	phosphorelay sensor kinase activity
H1D58_RS16280	COG0789	Transcriptional regulator
H1D58_RS16290	COG1174	glycine betaine transport
H1D58_RS16295	COG1125	glycine betaine transport
H1D58_RS16300	COG1174	glycine betaine transport
H1D58_RS16305	COG1732	Glycine betaine
H1D58_RS16310	COG1472	Belongs to the glycosyl hydrolase 3 family
H1D58_RS16315	COG0277	FAD linked oxidase domain protein
H1D58_RS16325	COG1686	Belongs to the peptidase S11 family
H1D58_RS16335	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS16345	COG1538	Outer membrane efflux protein
H1D58_RS16350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1D58_RS16360	COG1346	cytolysis
H1D58_RS16365	COG0295	cytidine deaminase activity
H1D58_RS16370	COG2949	membrane
H1D58_RS16380	COG1129	ABC transporter
H1D58_RS16395	COG2311	Membrane
H1D58_RS16405	COG0477	Major facilitator Superfamily
H1D58_RS16410	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H1D58_RS16415	COG4771	TonB-dependent receptor
H1D58_RS16420	COG0833	amino acid
H1D58_RS16425	COG0583	DNA-binding transcription factor activity
H1D58_RS16430	COG2855	membrane
H1D58_RS16435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H1D58_RS16440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS16440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D58_RS16440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1D58_RS16445	COG1105	Belongs to the carbohydrate kinase PfkB family
H1D58_RS16470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H1D58_RS16475	COG1312	Catalyzes the dehydration of D-mannonate
H1D58_RS16480	COG0246	Mannitol dehydrogenase
H1D58_RS16485	COG0523	cobalamin synthesis protein
H1D58_RS16490	COG0671	phosphoesterase, PA-phosphatase related
H1D58_RS16495	COG0791	NLP P60 protein
H1D58_RS16500	COG2200	EAL domain
H1D58_RS16505	COG4166	transmembrane transport
H1D58_RS16510	COG4174	ABC transporter (Permease)
H1D58_RS16515	COG4239	(ABC) transporter, permease
H1D58_RS16520	COG4172	Belongs to the ABC transporter superfamily
H1D58_RS16530	COG2814	Major facilitator Superfamily
H1D58_RS16535	COG1187	pseudouridine synthase activity
H1D58_RS16540	COG1061	Type III restriction enzyme res subunit
H1D58_RS16550	COG3081	Nucleoid-associated protein
H1D58_RS16555	COG3082	Protein of unknown function (DUF1414)
H1D58_RS16585	COG3121	Chaperone
H1D58_RS16600	COG3182	Iron-regulated membrane protein
H1D58_RS16610	COG0579	oxidoreductase
H1D58_RS16615	COG0659	secondary active sulfate transmembrane transporter activity
H1D58_RS16620	COG2239	Acts as a magnesium transporter
H1D58_RS16625	COG4615	Cyclic peptide transporter
H1D58_RS16635	COG2169	Transcriptional regulator
H1D58_RS16635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1D58_RS16645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1D58_RS16650	COG2198	Histidine kinase
H1D58_RS16650	COG0642	Histidine kinase
H1D58_RS16670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1D58_RS16685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D58_RS16690	COG0584	glycerophosphoryl diester phosphodiesterase
H1D58_RS16695	COG2271	Major facilitator Superfamily
H1D58_RS16700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1D58_RS16705	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
H1D58_RS16710	COG0247	lactate metabolic process
H1D58_RS16725	COG0642	Histidine kinase
H1D58_RS16755	COG1441	menaquinone biosynthetic process
H1D58_RS16765	COG0596	Alpha beta hydrolase
H1D58_RS16770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H1D58_RS16775	COG1169	isochorismate synthase
H1D58_RS16780	COG4575	ribosome binding
H1D58_RS16785	COG2153	protein acetylation
H1D58_RS16790	COG1234	tRNA 3'-trailer cleavage
H1D58_RS16795	COG0835	chemotaxis
H1D58_RS16795	COG0784	Response regulator, receiver
H1D58_RS16800	COG1007	ATP synthesis coupled electron transport
H1D58_RS16805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1D58_RS16810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1D58_RS16815	COG0713	ATP synthesis coupled electron transport
H1D58_RS16820	COG0839	Belongs to the complex I subunit 6 family
H1D58_RS16830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H1D58_RS16860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1D58_RS16865	COG0583	DNA-binding transcription factor activity
H1D58_RS16870	COG0436	Aminotransferase
H1D58_RS16880	COG0490	domain, Protein
H1D58_RS16880	COG0471	metal ion transport
H1D58_RS16885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D58_RS16910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1D58_RS16915	COG3959	Transketolase, thiamine diphosphate binding domain
H1D58_RS16920	COG3037	sugar-specific permease SgaT UlaA
H1D58_RS16930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS16935	COG1609	Transcriptional regulator
H1D58_RS16945	COG0622	Phosphoesterase
H1D58_RS16950	COG0625	glutathione transferase activity
H1D58_RS16955	COG0625	glutathione transferase activity
H1D58_RS16960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1D58_RS16965	COG1090	epimerase
H1D58_RS16970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS16975	COG4598	ABC transporter
H1D58_RS16980	COG4160	amino acid transport
H1D58_RS16990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D58_RS17000	COG0163	prenyltransferase activity
H1D58_RS17005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H1D58_RS17010	COG1286	toxin biosynthetic process
H1D58_RS17015	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H1D58_RS17020	COG0285	dihydrofolate synthase activity
H1D58_RS17025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H1D58_RS17030	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS17035	COG0101	tRNA pseudouridine synthase activity
H1D58_RS17040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1D58_RS17045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1D58_RS17060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1D58_RS17065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1D58_RS17065	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1D58_RS17075	COG3101	peptidyl-lysine hydroxylation
H1D58_RS17080	COG0730	response to heat
H1D58_RS17090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H1D58_RS17100	COG2840	Smr protein MutS2
H1D58_RS17105	COG2062	phosphohistidine phosphatase, SixA
H1D58_RS17110	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D58_RS17110	COG1024	Enoyl-CoA hydratase
H1D58_RS17120	COG3691	Protein conserved in bacteria
H1D58_RS17125	COG2067	long-chain fatty acid transport protein
H1D58_RS17135	COG2116	formate transmembrane transporter activity
H1D58_RS17145	COG1560	Kdo2-lipid A biosynthetic process
H1D58_RS17155	COG0436	Aminotransferase
H1D58_RS17160	COG3275	phosphorelay sensor kinase activity
H1D58_RS17165	COG3279	Response regulator of the LytR AlgR family
H1D58_RS17170	COG0837	glucose binding
H1D58_RS17180	COG3961	Belongs to the TPP enzyme family
H1D58_RS17185	COG0667	Aldo Keto reductase
H1D58_RS17195	COG1914	H( )-stimulated, divalent metal cation uptake system
H1D58_RS17200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1D58_RS17205	COG2200	EAL domain
H1D58_RS17205	COG2199	diguanylate cyclase activity
H1D58_RS17220	COG3415	Transposase
H1D58_RS17225	COG3415	Transposase
H1D58_RS17230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1D58_RS17260	COG0583	DNA-binding transcription factor activity
H1D58_RS17265	COG0385	Bile acid
H1D58_RS17270	COG3530	Putative quorum-sensing-regulated virulence factor
H1D58_RS17275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H1D58_RS17280	COG3115	cell septum assembly
H1D58_RS17295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS17320	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1D58_RS17325	COG4208	sulfate ABC transporter
H1D58_RS17330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1D58_RS17335	COG4150	thiosulfate binding
H1D58_RS17340	COG2837	iron assimilation
H1D58_RS17365	COG0408	coproporphyrinogen oxidase activity
H1D58_RS17380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1D58_RS17385	COG5342	invasion associated locus B
H1D58_RS17390	COG0494	nUDIX hydrolase
H1D58_RS17395	COG0493	'glutamate synthase
H1D58_RS17395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D58_RS17400	COG3850	Histidine kinase
H1D58_RS17405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS17415	COG1393	Belongs to the ArsC family
H1D58_RS17420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1D58_RS17430	COG0400	carboxylic ester hydrolase activity
H1D58_RS17440	COG2321	neutral zinc metallopeptidase
H1D58_RS17445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H1D58_RS17450	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H1D58_RS17460	COG2716	regulation of RNA biosynthetic process
H1D58_RS17465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1D58_RS17470	COG0628	permease
H1D58_RS17475	COG4783	chaperone-mediated protein folding
H1D58_RS17480	COG1393	Belongs to the ArsC family
H1D58_RS17495	COG1446	asparaginase
H1D58_RS17500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H1D58_RS17510	COG2233	PERMEase
H1D58_RS17515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H1D58_RS17520	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS17530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1D58_RS17545	COG2200	EAL domain
H1D58_RS17555	COG0583	DNA-binding transcription factor activity
H1D58_RS17580	COG2814	Major facilitator Superfamily
H1D58_RS17585	COG3718	enzyme involved in inositol metabolism
H1D58_RS17595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D58_RS17600	COG0673	inositol 2-dehydrogenase activity
H1D58_RS17605	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS17620	COG0673	inositol 2-dehydrogenase activity
H1D58_RS17625	COG3962	Belongs to the TPP enzyme family
H1D58_RS17660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS17665	COG2207	Transcriptional regulator
H1D58_RS17665	COG3708	Transcriptional regulator
H1D58_RS17675	COG0516	GMP reductase activity
H1D58_RS17675	COG0517	IMP dehydrogenase activity
H1D58_RS17680	COG1570	exodeoxyribonuclease VII activity
H1D58_RS17695	COG1645	bacterial-type flagellum-dependent swarming motility
H1D58_RS17700	COG3104	oligopeptide transport
H1D58_RS17705	COG1160	GTP binding
H1D58_RS17715	COG2976	Protein conserved in bacteria
H1D58_RS17720	COG0124	histidyl-tRNA synthetase
H1D58_RS17725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H1D58_RS17735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H1D58_RS17750	COG3302	dmso reductase anchor subunit
H1D58_RS17755	COG0437	4 iron, 4 sulfur cluster binding
H1D58_RS17760	COG0243	molybdopterin cofactor binding
H1D58_RS17765	COG4953	penicillin-binding protein 1C
H1D58_RS17770	COG2373	Large extracellular alpha-helical protein
H1D58_RS17775	COG1263	PTS System
H1D58_RS17775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS17775	COG2190	(PTS) system
H1D58_RS17785	COG2897	thiosulfate sulfurtransferase activity
H1D58_RS17790	COG1737	Transcriptional regulator
H1D58_RS17800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H1D58_RS17805	COG2975	iron-sulfur cluster assembly
H1D58_RS17810	COG0633	Ferredoxin
H1D58_RS17815	COG0443	Heat shock 70 kDa protein
H1D58_RS17820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1D58_RS17825	COG0316	Belongs to the HesB IscA family
H1D58_RS17830	COG0822	iron-sulfur transferase activity
H1D58_RS17835	COG1104	cysteine desulfurase activity
H1D58_RS17855	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H1D58_RS17865	COG3711	transcriptional antiterminator
H1D58_RS17870	COG2814	Major facilitator Superfamily
H1D58_RS17875	COG2259	Doxx family
H1D58_RS17885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D58_RS17885	COG1017	nitric oxide dioxygenase activity
H1D58_RS17890	COG0347	Belongs to the P(II) protein family
H1D58_RS17895	COG2204	response regulator
H1D58_RS17900	COG3170	Tfp pilus assembly protein FimV
H1D58_RS17905	COG2205	protein histidine kinase activity
H1D58_RS17910	COG0047	phosphoribosylformylglycinamidine synthase activity
H1D58_RS17910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1D58_RS17915	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H1D58_RS17925	COG0560	Phosphoserine phosphatase
H1D58_RS17930	COG1263	PTS System
H1D58_RS17930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS17935	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H1D58_RS17940	COG1737	Transcriptional regulator
H1D58_RS17945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D58_RS17955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1D58_RS17960	COG1381	Involved in DNA repair and RecF pathway recombination
H1D58_RS17975	COG0681	Belongs to the peptidase S26 family
H1D58_RS17990	COG0675	Transposase, IS605 OrfB family
H1D58_RS18145	COG3728	DNA packaging
H1D58_RS18145	COG5484	DNA packaging
H1D58_RS18160	COG3179	chitinase
H1D58_RS18245	COG1846	Transcriptional regulator
H1D58_RS18300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1D58_RS18330	COG3086	response to oxidative stress
H1D58_RS18350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H1D58_RS18355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H1D58_RS18360	COG0513	Belongs to the DEAD box helicase family
H1D58_RS18365	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
H1D58_RS18370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H1D58_RS18375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1D58_RS18380	COG3118	belongs to the thioredoxin family
H1D58_RS18390	COG0045	succinate-CoA ligase (ADP-forming) activity
H1D58_RS18390	COG1042	CoA-binding domain protein
H1D58_RS18390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS18395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1D58_RS18400	COG5544	Lipoprotein
H1D58_RS18405	COG0477	Major facilitator Superfamily
H1D58_RS18435	COG0542	response to heat
H1D58_RS18445	COG0564	pseudouridine synthase activity
H1D58_RS18450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1D58_RS18455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1D58_RS18465	COG1605	Chorismate mutase
H1D58_RS18465	COG0077	Prephenate dehydratase
H1D58_RS18475	COG1605	Chorismate mutase
H1D58_RS18475	COG0287	Prephenate dehydrogenase
H1D58_RS18480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1D58_RS18490	COG2199	diguanylate cyclase activity
H1D58_RS18495	COG2885	chlorophyll binding
H1D58_RS18515	COG0336	Belongs to the RNA methyltransferase TrmD family
H1D58_RS18520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1D58_RS18530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1D58_RS18535	COG4137	Cytochrome C assembly protein
H1D58_RS18540	COG4536	flavin adenine dinucleotide binding
H1D58_RS18545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H1D58_RS18550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1D58_RS18555	COG0497	DNA recombination
H1D58_RS18570	COG2867	negative regulation of translational initiation
H1D58_RS18585	COG0582	viral genome integration into host DNA
H1D58_RS18600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1D58_RS18620	COG3311	Transcriptional regulator
H1D58_RS18665	COG0210	DNA helicase
H1D58_RS18670	COG3596	GTP binding
H1D58_RS18680	COG2378	regulation of single-species biofilm formation
H1D58_RS18705	COG2003	Belongs to the UPF0758 family
H1D58_RS18730	COG0154	amidase activity
H1D58_RS18735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1D58_RS18755	COG0583	DNA-binding transcription factor activity
H1D58_RS18760	COG0401	homolog of Blt101
H1D58_RS18765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1D58_RS18790	COG4575	ribosome binding
H1D58_RS18800	COG1780	Probably involved in ribonucleotide reductase function
H1D58_RS18805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1D58_RS18815	COG4175	Glycine betaine
H1D58_RS18820	COG4176	ABC-type proline glycine betaine transport system permease component
H1D58_RS18830	COG2814	Major facilitator Superfamily
H1D58_RS18835	COG1846	Transcriptional regulator
H1D58_RS18840	COG1566	PFAM secretion protein HlyD family protein
H1D58_RS18845	COG2814	Major facilitator Superfamily
H1D58_RS18850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1D58_RS18860	COG2918	glutathione biosynthetic process
H1D58_RS18865	COG1238	metal cluster binding
H1D58_RS18870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D58_RS18900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H1D58_RS18905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H1D58_RS18920	COG1546	Belongs to the CinA family
H1D58_RS18930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1D58_RS18940	COG2951	lytic endotransglycosylase activity
H1D58_RS18945	COG3730	PTS system glucitol sorbitol-specific
H1D58_RS18950	COG3732	PTS system glucitol sorbitol-specific
H1D58_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS18965	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS18970	COG1349	DNA-binding transcription factor activity
H1D58_RS18980	COG3604	Transcriptional regulator
H1D58_RS18985	COG1773	rubredoxin
H1D58_RS18985	COG0426	domain, Protein
H1D58_RS18990	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1D58_RS18995	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H1D58_RS19000	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H1D58_RS19005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D58_RS19010	COG1609	Transcriptional regulator
H1D58_RS19015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS19015	COG1263	PTS System
H1D58_RS19020	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS19025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1D58_RS19035	COG3260	NADH ubiquinone oxidoreductase 20
H1D58_RS19040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1D58_RS19045	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H1D58_RS19045	COG3261	NADH dehydrogenase
H1D58_RS19050	COG0650	Formate hydrogenlyase subunit 4
H1D58_RS19055	COG0651	ATP synthesis coupled electron transport
H1D58_RS19060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D58_RS19070	COG0375	protein maturation
H1D58_RS19075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H1D58_RS19080	COG0298	carbon dioxide binding
H1D58_RS19085	COG0409	Hydrogenase expression formation protein
H1D58_RS19090	COG0309	Hydrogenase expression formation protein (HypE)
H1D58_RS19110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H1D58_RS19120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1D58_RS19125	COG0163	prenyltransferase activity
H1D58_RS19155	COG4942	peptidase
H1D58_RS19155	COG1388	LysM domain
H1D58_RS19170	COG0585	pseudouridine synthase activity
H1D58_RS19175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H1D58_RS19180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H1D58_RS19185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1D58_RS19195	COG0529	Catalyzes the synthesis of activated sulfate
H1D58_RS19215	COG2234	aminopeptidase activity
H1D58_RS19230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1D58_RS19235	COG0720	synthase
H1D58_RS19240	COG2207	Transcriptional regulator
H1D58_RS19245	COG1473	amidohydrolase
H1D58_RS19255	COG0602	queuosine metabolic process
H1D58_RS19260	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H1D58_RS19265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS19265	COG1263	PTS System
H1D58_RS19265	COG2190	(PTS) system
H1D58_RS19270	COG1737	Transcriptional regulator
H1D58_RS19285	COG3956	TIGRFAM MazG family protein
H1D58_RS19290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1D58_RS19295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1D58_RS19300	COG3850	Histidine kinase
H1D58_RS19300	COG3437	response regulator, receiver
H1D58_RS19300	COG4999	Histidine kinase
H1D58_RS19300	COG2205	protein histidine kinase activity
H1D58_RS19305	COG1929	Belongs to the glycerate kinase type-1 family
H1D58_RS19310	COG4948	Mandelate Racemase Muconate Lactonizing
H1D58_RS19315	COG4948	Mandelate Racemase Muconate Lactonizing
H1D58_RS19320	COG2271	Major facilitator Superfamily
H1D58_RS19325	COG0716	FMN binding
H1D58_RS19330	COG0564	pseudouridine synthase activity
H1D58_RS19335	COG3098	single-species biofilm formation
H1D58_RS19355	COG1611	Belongs to the LOG family
H1D58_RS19360	COG0814	amino acid
H1D58_RS19365	COG1760	l-serine dehydratase
H1D58_RS19375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
H1D58_RS19380	COG2363	Small membrane protein
H1D58_RS19385	COG0583	DNA-binding transcription factor activity
H1D58_RS19395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1D58_RS19400	COG2166	iron-sulfur cluster assembly
H1D58_RS19405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1D58_RS19410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H1D58_RS19430	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1D58_RS19435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H1D58_RS19435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H1D58_RS19440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1D58_RS19445	COG1074	ATP-dependent DNA helicase activity
H1D58_RS19455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1D58_RS19460	COG4967	type IV pilus modification protein PilV
H1D58_RS19470	COG4795	General secretion pathway protein
H1D58_RS19475	COG2165	general secretion pathway protein
H1D58_RS19480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H1D58_RS19485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H1D58_RS19495	COG0494	nUDIX hydrolase
H1D58_RS19500	COG3066	DNA modification
H1D58_RS19510	COG0667	Aldo Keto reductase
H1D58_RS19515	COG0477	Major facilitator Superfamily
H1D58_RS19520	COG0204	Acyl-transferase
H1D58_RS19520	COG0318	PFAM AMP-dependent synthetase and ligase
H1D58_RS19525	COG1609	Transcriptional regulator
H1D58_RS19535	COG2186	Transcriptional regulator
H1D58_RS19540	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS19545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1D58_RS19550	COG1609	Transcriptional regulator
H1D58_RS19560	COG0583	DNA-binding transcription factor activity
H1D58_RS19565	COG1794	racemase activity, acting on amino acids and derivatives
H1D58_RS19575	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
H1D58_RS19580	COG1175	transmembrane transport
H1D58_RS19585	COG0395	ABC-type sugar transport system, permease component
H1D58_RS19590	COG3842	ATPase activity
H1D58_RS19600	COG2814	Major facilitator Superfamily
H1D58_RS19605	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS19610	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H1D58_RS19615	COG0823	Involved in the tonB-independent uptake of proteins
H1D58_RS19620	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1D58_RS19625	COG0183	Belongs to the thiolase family
H1D58_RS19640	COG0814	amino acid
H1D58_RS19645	COG2388	GCN5-related N-acetyl-transferase
H1D58_RS19650	COG3592	Divergent 4Fe-4S mono-cluster
H1D58_RS19655	COG3729	General stress protein
H1D58_RS19660	COG3685	Protein conserved in bacteria
H1D58_RS19665	COG3685	Protein conserved in bacteria
H1D58_RS19670	COG3546	catalase activity
H1D58_RS19675	COG1271	oxidase subunit
H1D58_RS19680	COG1294	oxidase, subunit
H1D58_RS19695	COG1546	Belongs to the CinA family
H1D58_RS19710	COG3111	PFAM Bacterial OB fold (BOF) protein
H1D58_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS19720	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H1D58_RS19740	COG2067	long-chain fatty acid transport protein
H1D58_RS19745	COG1280	lysine exporter protein (LysE YggA)
H1D58_RS19760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1D58_RS19780	COG4942	peptidase
H1D58_RS19785	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H1D58_RS19790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H1D58_RS19800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1D58_RS19810	COG4974	Belongs to the 'phage' integrase family
H1D58_RS19825	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1D58_RS19830	COG0354	folic acid binding
H1D58_RS19835	COG1272	protein, Hemolysin III
H1D58_RS19840	COG1737	Transcriptional regulator
H1D58_RS19845	COG2723	6-phospho-beta-galactosidase activity
H1D58_RS19865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1D58_RS19870	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS19875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H1D58_RS19875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H1D58_RS19885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H1D58_RS19890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D58_RS19895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D58_RS19900	COG0006	proline dipeptidase activity
H1D58_RS19910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H1D58_RS19920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1D58_RS19930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1D58_RS19940	COG0583	DNA-binding transcription factor activity
H1D58_RS19945	COG2968	Membrane
H1D58_RS19950	COG1279	arginine transmembrane transporter activity
H1D58_RS19955	COG0668	transmembrane transport
H1D58_RS19960	COG0191	fructose-bisphosphate aldolase activity
H1D58_RS19965	COG0126	phosphoglycerate kinase activity
H1D58_RS19970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1D58_RS19975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1D58_RS19980	COG0501	Belongs to the peptidase M48B family
H1D58_RS19995	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H1D58_RS20000	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS20005	COG2267	carboxylic ester hydrolase activity
H1D58_RS20030	COG1414	Transcriptional regulator
H1D58_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS20050	COG2146	nitrite reductase [NAD(P)H] activity
H1D58_RS20060	COG0010	Belongs to the arginase family
H1D58_RS20065	COG1166	arginine decarboxylase activity
H1D58_RS20085	COG2814	Major facilitator Superfamily
H1D58_RS20090	COG3091	SprT-like family
H1D58_RS20095	COG2356	endonuclease I
H1D58_RS20100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1D58_RS20120	COG2805	Type II/IV secretion system protein
H1D58_RS20125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1D58_RS20130	COG0762	integral membrane protein
H1D58_RS20135	COG1872	DUF167
H1D58_RS20145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1D58_RS20150	COG2852	Protein conserved in bacteria
H1D58_RS20160	COG3171	Protein conserved in bacteria
H1D58_RS20170	COG1194	a g-specific adenine glycosylase
H1D58_RS20180	COG0741	lytic transglycosylase activity
H1D58_RS20185	COG2211	Major facilitator Superfamily
H1D58_RS20190	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1D58_RS20210	COG3052	prosthetic group binding
H1D58_RS20220	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1D58_RS20225	COG3493	citrate carrier protein
H1D58_RS20240	COG1982	Orn Lys Arg decarboxylase major
H1D58_RS20245	COG1811	Na channel or pump
H1D58_RS20270	COG5002	protein histidine kinase activity
H1D58_RS20275	COG2197	response regulator
H1D58_RS20295	COG0457	Tetratricopeptide repeat
H1D58_RS20305	COG1215	transferase activity, transferring glycosyl groups
H1D58_RS20315	COG0754	glutathionylspermidine amidase activity
H1D58_RS20320	COG0625	glutathione transferase activity
H1D58_RS20325	COG1349	DNA-binding transcription factor activity
H1D58_RS20330	COG0840	transmembrane signaling receptor activity
H1D58_RS20340	COG0667	Aldo Keto reductase
H1D58_RS20345	COG2862	Uncharacterized protein family, UPF0114
H1D58_RS20365	COG0848	biopolymer transport protein
H1D58_RS20375	COG0626	cystathionine gamma-synthase activity
H1D58_RS20380	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS20385	COG2207	Transcriptional regulator
H1D58_RS20390	COG1979	alcohol dehydrogenase
H1D58_RS20460	COG0604	alcohol dehydrogenase
H1D58_RS20495	COG3344	reverse transcriptase
H1D58_RS20540	COG0697	spore germination
H1D58_RS20545	COG1234	tRNA 3'-trailer cleavage
H1D58_RS20555	COG1902	pentaerythritol trinitrate reductase activity
H1D58_RS20560	COG0640	Transcriptional regulator
H1D58_RS20610	COG0204	Acyl-transferase
H1D58_RS20620	COG3111	PFAM Bacterial OB fold (BOF) protein
H1D58_RS20635	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D58_RS20640	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1D58_RS20645	COG1652	LysM domain
H1D58_RS20655	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H1D58_RS20660	COG2211	Major facilitator Superfamily
H1D58_RS20685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS20690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D58_RS20695	COG1120	ATPase activity
H1D58_RS20700	COG4774	siderophore transport
H1D58_RS20705	COG0187	DNA topoisomerase II activity
H1D58_RS20710	COG3150	esterase
H1D58_RS20715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1D58_RS20720	COG3151	Protein conserved in bacteria
H1D58_RS20725	COG0494	nUDIX hydrolase
H1D58_RS20740	COG0754	glutathionylspermidine amidase activity
H1D58_RS20745	COG3384	dioxygenase
H1D58_RS20755	COG3539	Fimbrial protein
H1D58_RS20765	COG3121	Chaperone
H1D58_RS20770	COG3539	Fimbrial protein
H1D58_RS20775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1D58_RS20785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H1D58_RS20785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H1D58_RS20795	COG3025	triphosphatase activity
H1D58_RS20800	COG4991	sh3 domain protein
H1D58_RS20805	COG0617	tRNA 3'-terminal CCA addition
H1D58_RS20815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1D58_RS20825	COG0477	Major facilitator Superfamily
H1D58_RS20830	COG0829	nickel cation binding
H1D58_RS20835	COG0831	urea catabolic process
H1D58_RS20840	COG0832	Belongs to the urease beta subunit family
H1D58_RS20845	COG0804	urea catabolic process
H1D58_RS20850	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H1D58_RS20860	COG0830	nickel cation binding
H1D58_RS20865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H1D58_RS20875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H1D58_RS20880	COG0358	DNA primase activity
H1D58_RS20890	COG3663	DNA glycosylase
H1D58_RS20935	COG2375	cellular response to nickel ion
H1D58_RS20940	COG1695	Transcriptional regulator
H1D58_RS20945	COG0840	transmembrane signaling receptor activity
H1D58_RS20950	COG0840	transmembrane signaling receptor activity
H1D58_RS20955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1D58_RS20960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1D58_RS20965	COG1830	Aldolase
H1D58_RS20970	COG1879	ABC-type sugar transport system periplasmic component
H1D58_RS20975	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS20980	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1D58_RS20985	COG1129	ABC transporter
H1D58_RS20990	COG2390	Transcriptional regulator
H1D58_RS20995	COG1070	Carbohydrate kinase
H1D58_RS21000	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1D58_RS21000	COG1902	pentaerythritol trinitrate reductase activity
H1D58_RS21010	COG1451	nucleotide metabolic process
H1D58_RS21015	COG0673	inositol 2-dehydrogenase activity
H1D58_RS21020	COG0861	Integral membrane protein TerC family
H1D58_RS21030	COG2721	sulfolactate sulfo-lyase activity
H1D58_RS21040	COG2271	Major facilitator Superfamily
H1D58_RS21045	COG2186	Transcriptional regulator
H1D58_RS21050	COG0586	Pfam SNARE associated Golgi protein
H1D58_RS21060	COG1422	Protein of unknown function (DUF1090)
H1D58_RS21065	COG4575	ribosome binding
H1D58_RS21070	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H1D58_RS21080	COG2259	Doxx family
H1D58_RS21085	COG0435	Glutathione S-transferase
H1D58_RS21090	COG3152	Membrane
H1D58_RS21095	COG0583	DNA-binding transcription factor activity
H1D58_RS21100	COG1741	Belongs to the pirin family
H1D58_RS21110	COG0814	amino acid
H1D58_RS21115	COG1882	Formate acetyltransferase
H1D58_RS21120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1D58_RS21125	COG0814	amino acid
H1D58_RS21130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1D58_RS21135	COG0583	DNA-binding transcription factor activity
H1D58_RS21145	COG1929	Belongs to the glycerate kinase type-1 family
H1D58_RS21150	COG2084	Dehydrogenase
H1D58_RS21160	COG2721	sulfolactate sulfo-lyase activity
H1D58_RS21165	COG1349	DNA-binding transcription factor activity
H1D58_RS21175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS21185	COG3716	PTS system mannose fructose sorbose family IID component
H1D58_RS21190	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS21195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1D58_RS21200	COG2222	sugar isomerase
H1D58_RS21205	COG0191	fructose-bisphosphate aldolase activity
H1D58_RS21210	COG1263	PTS System
H1D58_RS21210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1D58_RS21225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H1D58_RS21230	COG3107	peptidoglycan biosynthetic process
H1D58_RS21235	COG0792	nuclease activity
H1D58_RS21240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H1D58_RS21245	COG2823	Periplasmic or secreted lipoprotein
H1D58_RS21250	COG0701	Predicted permease
H1D58_RS21255	COG0702	epimerase
H1D58_RS21260	COG0693	protein deglycase activity
H1D58_RS21265	COG3787	Belongs to the UPF0306 family
H1D58_RS21270	COG2827	Endonuclease containing a URI domain
H1D58_RS21275	COG3153	acetyltransferase
H1D58_RS21280	COG3154	lipid carrier protein
H1D58_RS21285	COG0826	peptidase U32
H1D58_RS21290	COG0826	peptidase U32
H1D58_RS21295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D58_RS21300	COG0814	amino acid
H1D58_RS21305	COG0513	Belongs to the DEAD box helicase family
H1D58_RS21320	COG1185	polyribonucleotide nucleotidyltransferase activity
H1D58_RS21325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H1D58_RS21330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1D58_RS21335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H1D58_RS21340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H1D58_RS21360	COG0137	argininosuccinate synthase activity
H1D58_RS21370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1D58_RS21375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1D58_RS21380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1D58_RS21390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H1D58_RS21395	COG1534	Rna-binding protein
H1D58_RS21405	COG2027	D-alanyl-D-alanine carboxypeptidase
H1D58_RS21410	COG0745	RESPONSE REGULATOR receiver
H1D58_RS21415	COG0642	Histidine kinase
H1D58_RS21425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H1D58_RS21430	COG0697	spore germination
H1D58_RS21440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H1D58_RS21445	COG0142	geranyltranstransferase activity
H1D58_RS21450	COG3423	Transcriptional regulator
H1D58_RS21455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1D58_RS21460	COG5007	Belongs to the BolA IbaG family
H1D58_RS21465	COG3113	response to antibiotic
H1D58_RS21470	COG2854	intermembrane phospholipid transfer
H1D58_RS21475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1D58_RS21480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1D58_RS21485	COG1127	ABC transporter
H1D58_RS21490	COG0530	calcium, potassium:sodium antiporter activity
H1D58_RS21500	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1D58_RS21505	COG3117	lipopolysaccharide transmembrane transporter activity
H1D58_RS21510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1D58_RS21515	COG1137	ATPase activity
H1D58_RS21520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H1D58_RS21540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D58_RS21550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H1D58_RS21555	COG5002	protein histidine kinase activity
H1D58_RS21555	COG2198	Histidine kinase
H1D58_RS21555	COG0784	Response regulator, receiver
H1D58_RS21560	COG0795	lipopolysaccharide-transporting ATPase activity
H1D58_RS21565	COG0795	lipopolysaccharide-transporting ATPase activity
H1D58_RS21570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H1D58_RS21575	COG2927	DNA polymerase III (CHI subunit)
H1D58_RS21585	COG0456	acetyltransferase
H1D58_RS21590	COG1064	alcohol dehydrogenase
H1D58_RS21600	COG0433	COG0433 Predicted ATPase
H1D58_RS21605	COG1242	4 iron, 4 sulfur cluster binding
H1D58_RS21610	COG0067	glutamate synthase
H1D58_RS21610	COG0069	glutamate synthase activity
H1D58_RS21610	COG0070	glutamate synthase
H1D58_RS21615	COG0493	'glutamate synthase
H1D58_RS21620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1D58_RS21625	COG0402	S-adenosylhomocysteine deaminase activity
H1D58_RS21630	COG3539	Fimbrial protein
H1D58_RS21640	COG3188	usher protein
H1D58_RS21645	COG3121	Chaperone
H1D58_RS21650	COG3539	Fimbrial protein
H1D58_RS21655	COG3539	Fimbrial protein
H1D58_RS21660	COG2969	positive regulation of protein catabolic process
H1D58_RS21665	COG0625	glutathione transferase activity
H1D58_RS21670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1D58_RS21680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1D58_RS21685	COG3105	Protein conserved in bacteria
H1D58_RS21690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D58_RS21695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D58_RS21705	COG1438	arginine binding
H1D58_RS21715	COG2732	(Barnase) inhibitor
H1D58_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
H1D58_RS21725	COG1289	transmembrane transporter activity
H1D58_RS21740	COG0583	DNA-binding transcription factor activity
H1D58_RS21745	COG0312	modulator of DNA gyrase
H1D58_RS21750	COG3164	Protein of unknown function
H1D58_RS21755	COG1530	ribonuclease E activity
H1D58_RS21765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1D58_RS21770	COG1792	Involved in formation and maintenance of cell shape
H1D58_RS21775	COG1077	Cell shape determining protein MreB Mrl
H1D58_RS21780	COG2200	EAL domain
H1D58_RS21780	COG2199	diguanylate cyclase activity
H1D58_RS21785	COG0604	alcohol dehydrogenase
H1D58_RS21795	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H1D58_RS21800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H1D58_RS21805	COG0511	ligase activity, forming carbon-carbon bonds
H1D58_RS21810	COG0439	Biotin carboxylase
H1D58_RS21815	COG3924	membrane
H1D58_RS21820	COG4145	pantothenate transmembrane transporter activity
H1D58_RS21855	COG1309	transcriptional regulator
H1D58_RS21860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS21865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D58_RS21905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1D58_RS21915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H1D58_RS21920	COG0009	L-threonylcarbamoyladenylate synthase
H1D58_RS21925	COG0551	DNA topoisomerase type I activity
H1D58_RS21930	COG2922	Belongs to the Smg family
H1D58_RS21935	COG0758	DNA mediated transformation
H1D58_RS21940	COG0242	peptide deformylase activity
H1D58_RS21945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H1D58_RS21950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1D58_RS21950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1D58_RS21960	COG1970	mechanosensitive ion channel activity
H1D58_RS21965	COG3036	rescue of stalled ribosome
H1D58_RS21970	COG0789	Transcriptional regulator
H1D58_RS21985	COG0202	RNA polymerase activity
H1D58_RS21995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H1D58_RS22010	COG0201	protein transport
H1D58_RS22020	COG1841	ribosomal large subunit assembly
H1D58_RS22035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H1D58_RS22040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H1D58_RS22070	COG0255	Belongs to the universal ribosomal protein uL29 family
H1D58_RS22075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H1D58_RS22115	COG0051	transcription antitermination factor activity, RNA binding
H1D58_RS22155	COG2168	tRNA wobble position uridine thiolation
H1D58_RS22160	COG2923	Belongs to the DsrF TusC family
H1D58_RS22165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1D58_RS22170	COG2964	Protein conserved in bacteria
H1D58_RS22175	COG0545	Peptidyl-prolyl cis-trans isomerase
H1D58_RS22180	COG2900	Belongs to the SlyX family
H1D58_RS22185	COG1047	Peptidyl-prolyl cis-trans
H1D58_RS22190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1D58_RS22195	COG0475	glutathione-regulated potassium exporter activity
H1D58_RS22195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1D58_RS22200	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D58_RS22205	COG0488	(ABC) transporter
H1D58_RS22215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1D58_RS22225	COG0679	Auxin Efflux Carrier
H1D58_RS22255	COG0429	hydrolase of the alpha beta-hydrolase fold
H1D58_RS22260	COG3089	Belongs to the UPF0270 family
H1D58_RS22265	COG3954	Phosphoribulokinase
H1D58_RS22270	COG1765	OsmC-like protein
H1D58_RS22280	COG1289	transmembrane transporter activity
H1D58_RS22285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1D58_RS22290	COG0512	Glutamine amidotransferase of anthranilate synthase
H1D58_RS22295	COG2184	nucleotidyltransferase activity
H1D58_RS22305	COG0738	Major facilitator superfamily
H1D58_RS22310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D58_RS22320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1D58_RS22320	COG1648	precorrin-2 dehydrogenase activity
H1D58_RS22330	COG0180	Tryptophanyl-tRNA synthetase
H1D58_RS22340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1D58_RS22345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H1D58_RS22350	COG3266	domain, Protein
H1D58_RS22355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H1D58_RS22360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1D58_RS22365	COG4796	Type ii and iii secretion system protein
H1D58_RS22385	COG4972	Pilus assembly protein
H1D58_RS22390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1D58_RS22395	COG0494	nUDIX hydrolase
H1D58_RS22405	COG1011	Hydrolase
H1D58_RS22410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1D58_RS22415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1D58_RS22420	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1D58_RS22425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H1D58_RS22435	COG0745	RESPONSE REGULATOR receiver
H1D58_RS22440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1D58_RS22445	COG2183	response to ionizing radiation
H1D58_RS22450	COG1918	ferrous iron import across plasma membrane
H1D58_RS22470	COG1040	competence protein
H1D58_RS22480	COG2610	gluconate transmembrane transporter activity
H1D58_RS22485	COG1640	4-alpha-glucanotransferase
H1D58_RS22490	COG0058	SHG alpha-glucan phosphorylase activity
H1D58_RS22495	COG2909	trisaccharide binding
H1D58_RS22500	COG1349	DNA-binding transcription factor activity
H1D58_RS22505	COG0705	Rhomboid family
H1D58_RS22510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1D58_RS22515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1D58_RS22520	COG0058	SHG alpha-glucan phosphorylase activity
H1D58_RS22525	COG0297	glycogen (starch) synthase activity
H1D58_RS22530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H1D58_RS22535	COG1523	belongs to the glycosyl hydrolase 13 family
H1D58_RS22540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H1D58_RS22545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1D58_RS22550	COG2095	MarC family integral membrane protein
H1D58_RS22555	COG2610	gluconate transmembrane transporter activity
H1D58_RS22560	COG3265	gluconokinase activity
H1D58_RS22565	COG1609	Transcriptional regulator
H1D58_RS22570	COG1741	Belongs to the pirin family
H1D58_RS22575	COG0673	inositol 2-dehydrogenase activity
H1D58_RS22580	COG1247	-acetyltransferase
H1D58_RS22585	COG0405	Gamma-glutamyltransferase
H1D58_RS22595	COG0584	glycerophosphoryl diester phosphodiesterase
H1D58_RS22625	COG0411	ABC transporter
H1D58_RS22640	COG0683	leucine binding
H1D58_RS22650	COG0683	leucine binding
H1D58_RS22655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1D58_RS22660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1D58_RS22665	COG2177	Part of the ABC transporter FtsEX involved in
H1D58_RS22670	COG2884	Cell division ATP-binding protein ftsE
H1D58_RS22675	COG0552	protein localization to endoplasmic reticulum
H1D58_RS22680	COG0742	ribosomal rna small subunit methyltransferase
H1D58_RS22685	COG3776	membrane
H1D58_RS22695	COG3714	YhhN family
H1D58_RS22700	COG2217	Heavy metal translocating P-type atpase
H1D58_RS22715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1D58_RS22720	COG0425	Belongs to the sulfur carrier protein TusA family
H1D58_RS22725	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H1D58_RS22735	COG0628	permease
H1D58_RS22755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1D58_RS22775	COG1216	Glycosyl transferase, family 2
H1D58_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS22815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1D58_RS22825	COG3479	Phenolic acid decarboxylase
H1D58_RS22830	COG0583	DNA-binding transcription factor activity
H1D58_RS22835	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS22855	COG1414	Transcriptional regulator
H1D58_RS22860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1D58_RS22865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1D58_RS22875	COG2205	protein histidine kinase activity
H1D58_RS22880	COG0745	RESPONSE REGULATOR receiver
H1D58_RS22885	COG1276	copper resistance
H1D58_RS22890	COG2372	response to copper ion
H1D58_RS22895	COG3667	copper resistance
H1D58_RS22900	COG2132	Multicopper oxidase
H1D58_RS22910	COG0739	heme binding
H1D58_RS22940	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D58_RS23005	COG2081	HI0933 family
H1D58_RS23010	COG0306	phosphate transporter
H1D58_RS23020	COG0589	response to stress
H1D58_RS23025	COG0742	ribosomal rna small subunit methyltransferase
H1D58_RS23030	COG0339	signal peptide processing
H1D58_RS23035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1D58_RS23040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1D58_RS23055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1D58_RS23065	COG2197	response regulator
H1D58_RS23070	COG1028	Short-chain dehydrogenase reductase Sdr
H1D58_RS23075	COG0583	DNA-binding transcription factor activity
H1D58_RS23080	COG1295	ribonuclease BN
H1D58_RS23085	COG0477	Major facilitator Superfamily
H1D58_RS23090	COG2982	Protein involved in outer membrane biogenesis
H1D58_RS23095	COG2200	EAL domain
H1D58_RS23105	COG0612	Peptidase, M16
H1D58_RS23110	COG1301	dicarboxylic acid transport
H1D58_RS23115	COG2199	diguanylate cyclase activity
H1D58_RS23115	COG2200	EAL domain
H1D58_RS23120	COG0457	Tetratricopeptide repeat
H1D58_RS23120	COG3118	belongs to the thioredoxin family
H1D58_RS23125	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H1D58_RS23130	COG1215	transferase activity, transferring glycosyl groups
H1D58_RS23160	COG2194	sulfuric ester hydrolase activity
H1D58_RS23170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1D58_RS23200	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H1D58_RS23210	COG1739	Uncharacterized protein family UPF0029
H1D58_RS23215	COG0006	proline dipeptidase activity
H1D58_RS23220	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D58_RS23220	COG1024	Enoyl-CoA hydratase
H1D58_RS23225	COG0183	Belongs to the thiolase family
H1D58_RS23230	COG0751	glycine-tRNA ligase activity
H1D58_RS23235	COG0752	glycyl-tRNA synthetase alpha subunit
H1D58_RS23245	COG3274	enterobacterial common antigen metabolic process
H1D58_RS23250	COG1070	Carbohydrate kinase
H1D58_RS23255	COG2115	Belongs to the xylose isomerase family
H1D58_RS23340	COG1192	Involved in chromosome partitioning
H1D58_RS23430	COG0210	DNA helicase
H1D58_RS23570	COG4245	von Willebrand factor, type A
H1D58_RS23575	COG4245	von Willebrand factor, type A
H1D58_RS23725	COG3550	peptidyl-serine autophosphorylation
H1D58_RS23790	COG3547	Transposase (IS116 IS110 IS902 family)
H1D58_RS23860	COG0789	Transcriptional regulator
H1D58_RS23935	COG2194	sulfuric ester hydrolase activity
H1D58_RS23945	COG2205	protein histidine kinase activity
H1D58_RS24020	COG0659	secondary active sulfate transmembrane transporter activity
H1D58_RS24025	COG0589	response to stress
H1D58_RS24030	COG1393	Belongs to the ArsC family
H1D58_RS24035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1D58_RS24040	COG0640	Transcriptional regulator
H1D58_RS24045	COG0431	NADPH-dependent FMN reductase
H1D58_RS24050	COG2801	Transposase and inactivated derivatives
H1D58_RS24075	COG2801	Transposase and inactivated derivatives
H1D58_RS24105	COG3039	Transposase
H1D58_RS24145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D58_RS24145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1D58_RS24165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D58_RS24180	COG3157	Type VI secretion system effector, Hcp
H1D58_RS24350	COG2026	Addiction module toxin, RelE StbE family
H1D58_RS24355	COG3077	Addiction module antitoxin, RelB DinJ family
H1D58_RS24360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1D58_RS24370	COG3547	Transposase (IS116 IS110 IS902 family)
H1D58_RS24375	COG2801	Transposase and inactivated derivatives
H1D58_RS24560	COG2890	protein-(glutamine-N5) methyltransferase activity
H1D58_RS24620	COG0338	D12 class N6 adenine-specific DNA methyltransferase