locus-tag	class	description
GVI67_RS00010	COG0592	DNA-directed DNA polymerase activity
GVI67_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GVI67_RS00025	COG2186	Transcriptional regulator
GVI67_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS00035	COG0246	Mannitol dehydrogenase
GVI67_RS00040	COG1063	alcohol dehydrogenase
GVI67_RS00045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GVI67_RS00050	COG2271	Major facilitator Superfamily
GVI67_RS00055	COG0561	phosphatase activity
GVI67_RS00060	COG2186	Transcriptional regulator
GVI67_RS00065	COG3734	2-keto-3-deoxy-galactonokinase
GVI67_RS00070	COG0800	Aldolase
GVI67_RS00075	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS00080	COG2271	Major facilitator Superfamily
GVI67_RS00085	COG0823	Involved in the tonB-independent uptake of proteins
GVI67_RS00090	COG5645	(Lipo)protein
GVI67_RS00100	COG0071	Belongs to the small heat shock protein (HSP20) family
GVI67_RS00105	COG2985	domain, Protein
GVI67_RS00130	COG2188	Transcriptional regulator
GVI67_RS00145	COG2149	membrane
GVI67_RS00155	COG0641	radical SAM
GVI67_RS00170	COG2814	Major facilitator Superfamily
GVI67_RS00190	COG5499	transcription regulator containing HTH domain
GVI67_RS00200	COG0028	Belongs to the TPP enzyme family
GVI67_RS00205	COG0440	acetolactate synthase activity
GVI67_RS00210	COG2197	response regulator
GVI67_RS00220	COG2271	Major facilitator Superfamily
GVI67_RS00230	COG0596	Alpha beta hydrolase
GVI67_RS00240	COG0583	DNA-binding transcription factor activity
GVI67_RS00260	COG2814	Major facilitator Superfamily
GVI67_RS00270	COG0667	Aldo Keto reductase
GVI67_RS00280	COG0697	spore germination
GVI67_RS00285	COG4580	involved in the transport of maltose and maltodextrins
GVI67_RS00290	COG1447	Phosphotransferase system cellobiose-specific component IIA
GVI67_RS00295	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS00300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS00300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS00310	COG1609	Transcriptional regulator
GVI67_RS00320	COG0454	-acetyltransferase
GVI67_RS00325	COG1309	transcriptional regulator
GVI67_RS00340	COG1487	ribonuclease activity
GVI67_RS00350	COG1464	Belongs to the NlpA lipoprotein family
GVI67_RS00380	COG3121	Chaperone
GVI67_RS00410	COG3188	usher protein
GVI67_RS00435	COG2274	protein secretion by the type I secretion system
GVI67_RS00450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GVI67_RS00465	COG3272	Protein of unknown function (DUF1722)
GVI67_RS00470	COG2351	hydroxyisourate hydrolase activity
GVI67_RS00475	COG0789	Transcriptional regulator
GVI67_RS00500	COG3121	Chaperone
GVI67_RS00530	COG0431	NADPH-dependent FMN reductase
GVI67_RS00560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GVI67_RS00585	COG0210	DNA helicase
GVI67_RS00590	COG0582	viral genome integration into host DNA
GVI67_RS00600	COG2211	Major facilitator Superfamily
GVI67_RS00605	COG1501	Belongs to the glycosyl hydrolase 31 family
GVI67_RS00610	COG2982	Protein involved in outer membrane biogenesis
GVI67_RS00615	COG2233	PERMEase
GVI67_RS00620	COG0786	glutamate:sodium symporter activity
GVI67_RS00625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GVI67_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI67_RS00635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GVI67_RS00650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GVI67_RS00685	COG1596	polysaccharide export
GVI67_RS00690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GVI67_RS00695	COG0489	protein tyrosine kinase activity
GVI67_RS00695	COG3206	protein involved in exopolysaccharide biosynthesis
GVI67_RS00700	COG2860	membrane
GVI67_RS00705	COG1561	YicC-like family, N-terminal region
GVI67_RS00715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GVI67_RS00725	COG0756	dUTP diphosphatase activity
GVI67_RS00730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GVI67_RS00735	COG2003	Belongs to the UPF0758 family
GVI67_RS00740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GVI67_RS00745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GVI67_RS00750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GVI67_RS00755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GVI67_RS00765	COG1519	Transferase
GVI67_RS00770	COG1216	Glycosyl transferase, family 2
GVI67_RS00775	COG0438	transferase activity, transferring glycosyl groups
GVI67_RS00785	COG0859	PFAM glycosyl transferase family 9
GVI67_RS00810	COG0859	PFAM glycosyl transferase family 9
GVI67_RS00815	COG0859	PFAM glycosyl transferase family 9
GVI67_RS00830	COG1063	alcohol dehydrogenase
GVI67_RS00845	COG2861	carbohydrate metabolic process
GVI67_RS00850	COG4942	peptidase
GVI67_RS00855	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GVI67_RS00860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI67_RS00865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GVI67_RS00870	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GVI67_RS00875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GVI67_RS00885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI67_RS00895	COG0248	Ppx GppA phosphatase
GVI67_RS00905	COG3118	belongs to the thioredoxin family
GVI67_RS00910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GVI67_RS00915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GVI67_RS00925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GVI67_RS00930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GVI67_RS00935	COG0456	acetyltransferase
GVI67_RS00940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GVI67_RS00945	COG2244	polysaccharide biosynthetic process
GVI67_RS00960	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GVI67_RS00990	COG3071	HemY protein
GVI67_RS00995	COG2959	enzyme of heme biosynthesis
GVI67_RS01005	COG0181	hydroxymethylbilane synthase activity
GVI67_RS01040	COG1011	Hydrolase
GVI67_RS01045	COG0210	DNA helicase
GVI67_RS01065	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GVI67_RS01075	COG1280	lysine exporter protein (LysE YggA)
GVI67_RS01080	COG1280	lysine exporter protein (LysE YggA)
GVI67_RS01085	COG2267	carboxylic ester hydrolase activity
GVI67_RS01090	COG0561	phosphatase activity
GVI67_RS01095	COG0697	spore germination
GVI67_RS01100	COG0583	DNA-binding transcription factor activity
GVI67_RS01110	COG3842	ATPase activity
GVI67_RS01120	COG1609	Transcriptional regulator
GVI67_RS01130	COG1175	transmembrane transport
GVI67_RS01135	COG0395	ABC-type sugar transport system, permease component
GVI67_RS01140	COG0366	Alpha amylase catalytic
GVI67_RS01150	COG0412	Dienelactone hydrolase
GVI67_RS01160	COG1322	Protein conserved in bacteria
GVI67_RS01165	COG2226	methyltransferase
GVI67_RS01170	COG3165	ubiquinone biosynthetic process from chorismate
GVI67_RS01175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GVI67_RS01185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GVI67_RS01190	COG0805	protein transport
GVI67_RS01195	COG0084	hydrolase, TatD family'
GVI67_RS01205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GVI67_RS01215	COG0488	(ABC) transporter
GVI67_RS01220	COG2944	sequence-specific DNA binding
GVI67_RS01230	COG1278	Cold shock
GVI67_RS01235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GVI67_RS01245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI67_RS01255	COG1609	Transcriptional regulator
GVI67_RS01260	COG2885	chlorophyll binding
GVI67_RS01265	COG0243	molybdopterin cofactor binding
GVI67_RS01270	COG0456	acetyltransferase
GVI67_RS01275	COG2818	Glycosylase
GVI67_RS01280	COG5571	outer membrane autotransporter
GVI67_RS01285	COG2223	nitrite transmembrane transporter activity
GVI67_RS01325	COG0747	negative chemotaxis
GVI67_RS01330	COG0601	transmembrane transport
GVI67_RS01335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI67_RS01340	COG0444	Belongs to the ABC transporter superfamily
GVI67_RS01345	COG4608	Belongs to the ABC transporter superfamily
GVI67_RS01350	COG1072	(Pantothenic acid kinase))
GVI67_RS01385	COG0250	Participates in transcription elongation, termination and antitermination
GVI67_RS01430	COG3706	GGDEF domain
GVI67_RS01440	COG2022	thiamine diphosphate biosynthetic process
GVI67_RS01445	COG2104	thiamine diphosphate biosynthetic process
GVI67_RS01450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GVI67_RS01465	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GVI67_RS01475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GVI67_RS01480	COG1515	deoxyribonuclease V activity
GVI67_RS01485	COG3068	Protein conserved in bacteria
GVI67_RS01500	COG0151	Belongs to the GarS family
GVI67_RS01530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GVI67_RS01540	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GVI67_RS01570	COG1187	pseudouridine synthase activity
GVI67_RS01585	COG0527	aspartate kinase activity
GVI67_RS01610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI67_RS01615	COG3223	Belongs to the PsiE family
GVI67_RS01640	COG4580	involved in the transport of maltose and maltodextrins
GVI67_RS01650	COG3161	chorismate lyase activity
GVI67_RS01660	COG2937	Belongs to the GPAT DAPAT family
GVI67_RS01665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GVI67_RS01670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GVI67_RS01675	COG0534	Mate efflux family protein
GVI67_RS01680	COG3237	CsbD-like
GVI67_RS01685	COG0735	belongs to the Fur family
GVI67_RS01710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GVI67_RS01720	COG0604	alcohol dehydrogenase
GVI67_RS01725	COG0305	Participates in initiation and elongation during chromosome replication
GVI67_RS01735	COG1448	Aminotransferase
GVI67_RS01740	COG3700	Belongs to the class B bacterial acid phosphatase family
GVI67_RS01750	COG2315	Protein conserved in bacteria
GVI67_RS01760	COG0629	single-stranded DNA binding
GVI67_RS01770	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GVI67_RS01780	COG0789	Transcriptional regulator
GVI67_RS01785	COG0625	glutathione transferase activity
GVI67_RS01790	COG2252	PERMEase
GVI67_RS01795	COG0025	NhaP-type Na H and K H
GVI67_RS01800	COG0583	DNA-binding transcription factor activity
GVI67_RS01810	COG1346	cytolysis
GVI67_RS01815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GVI67_RS01820	COG3162	membrane
GVI67_RS01830	COG1301	dicarboxylic acid transport
GVI67_RS01835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GVI67_RS01860	COG0191	fructose-bisphosphate aldolase activity
GVI67_RS01875	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS01880	COG1129	ABC transporter
GVI67_RS01885	COG0784	Response regulator, receiver
GVI67_RS01885	COG4191	Histidine kinase
GVI67_RS01895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GVI67_RS01900	COG0456	acetyltransferase
GVI67_RS01905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GVI67_RS01910	COG3454	Phosphonate metabolism
GVI67_RS01915	COG4778	phosphonate C-P lyase system protein PhnL
GVI67_RS01920	COG4107	phosphonate C-P lyase system protein PhnK
GVI67_RS01925	COG3627	carbon phosphorus lyase activity
GVI67_RS01930	COG3626	phosphonate metabolism
GVI67_RS01935	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GVI67_RS01940	COG3624	Phosphonate C-P lyase system protein PhnG
GVI67_RS01945	COG2188	Transcriptional regulator
GVI67_RS01950	COG3639	organic phosphonate transmembrane transporter activity
GVI67_RS01955	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GVI67_RS01965	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GVI67_RS01970	COG2824	Alkylphosphonate utilization operon protein PhnA
GVI67_RS01975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GVI67_RS01995	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GVI67_RS02020	COG3647	Membrane
GVI67_RS02040	COG1309	transcriptional regulator
GVI67_RS02055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GVI67_RS02060	COG1027	Aspartate ammonia-lyase
GVI67_RS02065	COG3030	protein affecting phage T7 exclusion by the F plasmid
GVI67_RS02070	COG0531	amino acid
GVI67_RS02080	COG0459	protein refolding
GVI67_RS02085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GVI67_RS02090	COG0700	Nucleoside recognition
GVI67_RS02095	COG3366	ferrous iron transmembrane transporter activity
GVI67_RS02120	COG5510	response to toxic substance
GVI67_RS02135	COG3040	lipid binding
GVI67_RS02145	COG0583	DNA-binding transcription factor activity
GVI67_RS02155	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GVI67_RS02160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GVI67_RS02165	COG1053	succinate dehydrogenase
GVI67_RS02170	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GVI67_RS02180	COG3264	Mechanosensitive ion channel
GVI67_RS02180	COG1511	domain protein
GVI67_RS02215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GVI67_RS02220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GVI67_RS02220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GVI67_RS02225	COG0802	atpase or kinase
GVI67_RS02235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GVI67_RS02240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GVI67_RS02245	COG1923	regulation of RNA biosynthetic process
GVI67_RS02250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GVI67_RS02255	COG0330	HflC and HflK could
GVI67_RS02260	COG0330	HflC and HflK could
GVI67_RS02265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GVI67_RS02275	COG1959	2 iron, 2 sulfur cluster binding
GVI67_RS02280	COG0557	exoribonuclease II activity
GVI67_RS02285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI67_RS02290	COG0477	Major facilitator Superfamily
GVI67_RS02295	COG1960	acyl-CoA dehydrogenase activity
GVI67_RS02310	COG3650	response to hydrogen peroxide
GVI67_RS02315	COG1073	alpha beta
GVI67_RS02330	COG3037	sugar-specific permease SgaT UlaA
GVI67_RS02370	COG2965	DNA replication, synthesis of RNA primer
GVI67_RS02375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GVI67_RS02380	COG0359	binds to the 23S rRNA
GVI67_RS02385	COG0697	spore germination
GVI67_RS02390	COG3061	Opacity-associated protein A
GVI67_RS02395	COG0545	Peptidyl-prolyl cis-trans isomerase
GVI67_RS02400	COG1113	amino acid transport
GVI67_RS02410	COG0840	transmembrane signaling receptor activity
GVI67_RS02415	COG0697	spore germination
GVI67_RS02425	COG0702	epimerase
GVI67_RS02430	COG1733	regulation of RNA biosynthetic process
GVI67_RS02440	COG1218	3'(2'),5'-bisphosphate nucleotidase
GVI67_RS02445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GVI67_RS02455	COG1253	flavin adenine dinucleotide binding
GVI67_RS02475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GVI67_RS02480	COG0729	surface antigen
GVI67_RS02485	COG2911	Protein conserved in bacteria
GVI67_RS02490	COG2105	PFAM AIG2 family protein
GVI67_RS02500	COG1879	ABC-type sugar transport system periplasmic component
GVI67_RS02505	COG1129	ABC transporter
GVI67_RS02510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS02515	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS02530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GVI67_RS02535	COG3028	Belongs to the UPF0307 family
GVI67_RS02540	COG0312	modulator of DNA gyrase
GVI67_RS02575	COG3964	amidohydrolase
GVI67_RS02595	COG3711	transcriptional antiterminator
GVI67_RS02595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS02600	COG0602	queuosine metabolic process
GVI67_RS02610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS02610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS02610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS02635	COG0366	Alpha amylase catalytic
GVI67_RS02640	COG1263	PTS System
GVI67_RS02640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS02665	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GVI67_RS02670	COG3397	chitin binding
GVI67_RS02675	COG0251	oxidation-reduction process
GVI67_RS02685	COG0540	Belongs to the ATCase OTCase family
GVI67_RS02700	COG1438	arginine binding
GVI67_RS02705	COG1288	antiporter activity
GVI67_RS02720	COG2235	arginine
GVI67_RS02725	COG2731	YhcH YjgK YiaL family protein
GVI67_RS02730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GVI67_RS02735	COG0129	dihydroxy-acid dehydratase activity
GVI67_RS02740	COG2211	Major facilitator Superfamily
GVI67_RS02745	COG3507	Belongs to the glycosyl hydrolase 43 family
GVI67_RS02750	COG1414	Transcriptional regulator
GVI67_RS02755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GVI67_RS02780	COG0582	viral genome integration into host DNA
GVI67_RS02800	COG1335	isochorismatase
GVI67_RS02815	COG2204	response regulator
GVI67_RS02820	COG4191	Histidine kinase
GVI67_RS02825	COG4566	intracellular signal transduction
GVI67_RS02830	COG0740	serine-type endopeptidase activity
GVI67_RS02835	COG2850	peptidyl-arginine hydroxylation
GVI67_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GVI67_RS02855	COG5457	Domain of unknown function (DUF1127)
GVI67_RS02865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI67_RS02870	COG0583	DNA-binding transcription factor activity
GVI67_RS02875	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS02890	COG0640	Transcriptional regulator
GVI67_RS02900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS02910	COG2733	membrane
GVI67_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS02935	COG0523	cobalamin synthesis protein
GVI67_RS02940	COG2879	small protein
GVI67_RS02945	COG1966	Carbon starvation protein
GVI67_RS02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GVI67_RS02955	COG2368	4-hydroxyphenylacetate
GVI67_RS02975	COG3971	2-oxopent-4-enoate hydratase activity
GVI67_RS02985	COG3384	dioxygenase
GVI67_RS02990	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS02995	COG0179	Fumarylacetoacetate (FAA) hydrolase
GVI67_RS03000	COG1846	Transcriptional regulator
GVI67_RS03005	COG0840	transmembrane signaling receptor activity
GVI67_RS03060	COG1484	DNA-dependent DNA replication
GVI67_RS03070	COG1764	response to oxidative stress
GVI67_RS03075	COG1846	Transcriptional regulator
GVI67_RS03080	COG3610	response to peptide
GVI67_RS03085	COG2966	Psort location CytoplasmicMembrane, score
GVI67_RS03090	COG2197	response regulator
GVI67_RS03095	COG2197	response regulator
GVI67_RS03100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GVI67_RS03105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS03110	COG4114	ferric iron reductase
GVI67_RS03140	COG2813	Specifically methylates the guanine in position
GVI67_RS03145	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GVI67_RS03150	COG0456	acetyltransferase
GVI67_RS03155	COG1011	Hydrolase
GVI67_RS03160	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GVI67_RS03165	COG2823	Periplasmic or secreted lipoprotein
GVI67_RS03170	COG5487	UPF0391 membrane protein
GVI67_RS03175	COG4667	esterase of the alpha-beta hydrolase superfamily
GVI67_RS03180	COG0084	hydrolase, TatD family'
GVI67_RS03185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI67_RS03190	COG1328	CTP reductase activity
GVI67_RS03200	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GVI67_RS03225	COG3726	membrane protein affecting hemolysin expression
GVI67_RS03230	COG0560	Phosphoserine phosphatase
GVI67_RS03245	COG0604	alcohol dehydrogenase
GVI67_RS03255	COG0488	(ABC) transporter
GVI67_RS03260	COG0741	lytic transglycosylase activity
GVI67_RS03265	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GVI67_RS03270	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GVI67_RS03275	COG0406	alpha-ribazole phosphatase activity
GVI67_RS03280	COG2207	Transcriptional regulator
GVI67_RS03280	COG3708	Transcriptional regulator
GVI67_RS03285	COG3045	CreA protein
GVI67_RS03290	COG0745	RESPONSE REGULATOR receiver
GVI67_RS03295	COG2205	protein histidine kinase activity
GVI67_RS03300	COG4452	Inner membrane protein CreD
GVI67_RS03305	COG0745	RESPONSE REGULATOR receiver
GVI67_RS03315	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GVI67_RS03325	COG0460	homoserine dehydrogenase
GVI67_RS03325	COG0527	aspartate kinase activity
GVI67_RS03335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GVI67_RS03350	COG1115	amino acid carrier protein
GVI67_RS03360	COG0521	Mo-molybdopterin cofactor biosynthetic process
GVI67_RS03365	COG0477	Major facilitator Superfamily
GVI67_RS03370	COG1584	GPR1 FUN34 yaaH family protein
GVI67_RS03375	COG0443	Heat shock 70 kDa protein
GVI67_RS03385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GVI67_RS03390	COG0583	DNA-binding transcription factor activity
GVI67_RS03395	COG0268	Binds directly to 16S ribosomal RNA
GVI67_RS03400	COG0196	riboflavin kinase activity
GVI67_RS03415	COG1047	Peptidyl-prolyl cis-trans
GVI67_RS03420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GVI67_RS03425	COG2140	Oxalate decarboxylase
GVI67_RS03435	COG3716	PTS system mannose fructose sorbose family IID component
GVI67_RS03440	COG3715	PTS system
GVI67_RS03445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS03460	COG1609	Transcriptional regulator
GVI67_RS03470	COG0505	Belongs to the CarA family
GVI67_RS03495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GVI67_RS03495	COG0475	glutathione-regulated potassium exporter activity
GVI67_RS03505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GVI67_RS03510	COG2967	ApaG domain
GVI67_RS03520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GVI67_RS03525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI67_RS03530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI67_RS03535	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GVI67_RS03540	COG0564	pseudouridine synthase activity
GVI67_RS03545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GVI67_RS03550	COG0417	DNA replication proofreading
GVI67_RS03555	COG0235	Class ii aldolase
GVI67_RS03560	COG2160	L-arabinose isomerase activity
GVI67_RS03565	COG1069	ribulokinase activity
GVI67_RS03575	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS03585	COG1178	ABC-type Fe3 transport system permease component
GVI67_RS03605	COG2814	Major facilitator Superfamily
GVI67_RS03630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GVI67_RS03645	COG0028	Belongs to the TPP enzyme family
GVI67_RS03655	COG1609	Transcriptional regulator
GVI67_RS03660	COG2001	Belongs to the MraZ family
GVI67_RS03675	COG0768	penicillin binding
GVI67_RS03680	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GVI67_RS03685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GVI67_RS03690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GVI67_RS03700	COG0772	Belongs to the SEDS family
GVI67_RS03715	COG1181	Belongs to the D-alanine--D-alanine ligase family
GVI67_RS03725	COG0849	cell division
GVI67_RS03730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GVI67_RS03735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GVI67_RS03745	COG0653	protein targeting
GVI67_RS03750	COG0494	nUDIX hydrolase
GVI67_RS03755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GVI67_RS03760	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GVI67_RS03770	COG0516	GMP reductase activity
GVI67_RS03775	COG1459	type II secretion system
GVI67_RS03780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI67_RS03785	COG4969	Belongs to the N-Me-Phe pilin family
GVI67_RS03795	COG3023	N-Acetylmuramoyl-L-alanine amidase
GVI67_RS03800	COG3725	Membrane protein required for beta-lactamase induction
GVI67_RS03805	COG3940	Belongs to the glycosyl hydrolase 43 family
GVI67_RS03810	COG2211	Major facilitator Superfamily
GVI67_RS03815	COG1113	amino acid transport
GVI67_RS03820	COG2186	Transcriptional regulator
GVI67_RS03825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GVI67_RS03830	COG0508	dehydrogenase complex catalyzes the overall conversion of
GVI67_RS03835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI67_RS03850	COG3064	Membrane
GVI67_RS03870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GVI67_RS03880	COG2132	Multicopper oxidase
GVI67_RS03885	COG4993	Dehydrogenase
GVI67_RS03895	COG0288	reversible hydration of carbon dioxide
GVI67_RS03900	COG1131	(ABC) transporter
GVI67_RS03905	COG0842	Transport permease protein
GVI67_RS03910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS03915	COG0726	polysaccharide deacetylase
GVI67_RS03940	COG3188	usher protein
GVI67_RS03945	COG3121	Chaperone
GVI67_RS03955	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GVI67_RS03960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GVI67_RS03970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GVI67_RS03975	COG0617	tRNA 3'-terminal CCA addition
GVI67_RS03990	COG1489	DNA binding
GVI67_RS03995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GVI67_RS04000	COG1643	Atp-dependent helicase
GVI67_RS04005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GVI67_RS04010	COG4774	siderophore transport
GVI67_RS04015	COG1120	ATPase activity
GVI67_RS04020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GVI67_RS04025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS04030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GVI67_RS04040	COG0316	Belongs to the HesB IscA family
GVI67_RS04045	COG2860	membrane
GVI67_RS04055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GVI67_RS04060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GVI67_RS04070	COG3835	regulator
GVI67_RS04100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GVI67_RS04115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GVI67_RS04125	COG0575	Belongs to the CDS family
GVI67_RS04130	COG0750	zinc metalloprotease
GVI67_RS04135	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI67_RS04150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GVI67_RS04155	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GVI67_RS04160	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GVI67_RS04165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GVI67_RS04175	COG0825	malonyl-CoA metabolic process
GVI67_RS04180	COG1982	Orn Lys Arg decarboxylase major
GVI67_RS04185	COG0346	lactoylglutathione lyase activity
GVI67_RS04190	COG0037	tRNA processing
GVI67_RS04195	COG4568	rho-dependent transcription termination
GVI67_RS04210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GVI67_RS04215	COG3015	lipoprotein NlpE involved in copper resistance
GVI67_RS04225	COG1720	tRNA m6t6A37 methyltransferase activity
GVI67_RS04235	COG1464	Belongs to the NlpA lipoprotein family
GVI67_RS04240	COG2011	ABC-type metal ion transport system permease component
GVI67_RS04250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GVI67_RS04290	COG0583	DNA-binding transcription factor activity
GVI67_RS04295	COG2814	Major facilitator Superfamily
GVI67_RS04300	COG3021	interspecies interaction between organisms
GVI67_RS04305	COG2226	methyltransferase
GVI67_RS04310	COG1388	LysM domain
GVI67_RS04310	COG0741	lytic transglycosylase activity
GVI67_RS04315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GVI67_RS04320	COG2226	methyltransferase
GVI67_RS04340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI67_RS04345	COG1960	acyl-CoA dehydrogenase activity
GVI67_RS04355	COG0121	glutamine amidotransferase
GVI67_RS04360	COG3034	peptidoglycan biosynthetic process
GVI67_RS04375	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GVI67_RS04380	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GVI67_RS04395	COG2991	Protein conserved in bacteria
GVI67_RS04400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GVI67_RS04405	COG2195	Cleaves the N-terminal amino acid of tripeptides
GVI67_RS04415	COG1073	alpha beta
GVI67_RS04425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI67_RS04430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GVI67_RS04435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GVI67_RS04465	COG2003	Belongs to the UPF0758 family
GVI67_RS04480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GVI67_RS04490	COG1902	pentaerythritol trinitrate reductase activity
GVI67_RS04505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS04510	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS04530	COG2378	regulation of single-species biofilm formation
GVI67_RS04540	COG3596	GTP binding
GVI67_RS04550	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS04560	COG3039	Transposase
GVI67_RS04565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI67_RS04615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GVI67_RS04625	COG0542	response to heat
GVI67_RS04720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GVI67_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS04760	COG0583	DNA-binding transcription factor activity
GVI67_RS04775	COG0628	permease
GVI67_RS04780	COG0833	amino acid
GVI67_RS04785	COG2040	homocysteine
GVI67_RS04790	COG4521	taurine ABC transporter
GVI67_RS04795	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GVI67_RS04800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GVI67_RS04805	COG2175	clavaminate synthase activity
GVI67_RS04815	COG0113	porphobilinogen synthase activity
GVI67_RS04830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GVI67_RS04835	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GVI67_RS04855	COG1181	Belongs to the D-alanine--D-alanine ligase family
GVI67_RS04880	COG3706	GGDEF domain
GVI67_RS04885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GVI67_RS04890	COG1671	Belongs to the UPF0178 family
GVI67_RS04895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GVI67_RS04905	COG4126	flavin adenine dinucleotide binding
GVI67_RS04910	COG3123	guanosine phosphorylase activity
GVI67_RS04920	COG1940	carbohydrate kinase activity
GVI67_RS04925	COG0419	ATPase involved in DNA repair
GVI67_RS04930	COG0420	3'-5' exonuclease activity
GVI67_RS04940	COG5002	protein histidine kinase activity
GVI67_RS04955	COG0366	Alpha amylase catalytic
GVI67_RS04970	COG0450	alkyl hydroperoxide reductase
GVI67_RS04975	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GVI67_RS04990	COG1862	Preprotein translocase
GVI67_RS04995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GVI67_RS05000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GVI67_RS05015	COG3248	Nucleoside-binding outer membrane protein
GVI67_RS05020	COG4238	major outer membrane lipoprotein
GVI67_RS05025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GVI67_RS05030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GVI67_RS05030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GVI67_RS05035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GVI67_RS05040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GVI67_RS05045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GVI67_RS05050	COG0667	Aldo Keto reductase
GVI67_RS05055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GVI67_RS05060	COG0142	geranyltranstransferase activity
GVI67_RS05090	COG3539	Fimbrial protein
GVI67_RS05095	COG2814	Major facilitator Superfamily
GVI67_RS05100	COG0235	Class ii aldolase
GVI67_RS05110	COG1070	Carbohydrate kinase
GVI67_RS05120	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS05125	COG1129	ABC transporter
GVI67_RS05145	COG0109	protoheme IX farnesyltransferase activity
GVI67_RS05150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GVI67_RS05155	COG1845	cytochrome c oxidase, subunit III
GVI67_RS05160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GVI67_RS05165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GVI67_RS05170	COG2223	nitrite transmembrane transporter activity
GVI67_RS05175	COG3056	Lipoprotein
GVI67_RS05180	COG0271	Belongs to the BolA IbaG family
GVI67_RS05185	COG0544	peptidyl-prolyl cis-trans isomerase activity
GVI67_RS05200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GVI67_RS05205	COG0776	regulation of translation
GVI67_RS05210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GVI67_RS05215	COG1555	photosystem II stabilization
GVI67_RS05220	COG0824	Thioesterase
GVI67_RS05225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GVI67_RS05230	COG4533	DNA binding
GVI67_RS05235	COG0561	phosphatase activity
GVI67_RS05245	COG1522	sequence-specific DNA binding
GVI67_RS05250	COG1132	(ABC) transporter
GVI67_RS05255	COG1132	(ABC) transporter
GVI67_RS05260	COG0347	Belongs to the P(II) protein family
GVI67_RS05265	COG0004	ammonium transporteR
GVI67_RS05270	COG1946	Acyl-CoA thioesterase
GVI67_RS05275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GVI67_RS05280	COG3695	enzyme binding
GVI67_RS05300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GVI67_RS05305	COG2364	Membrane
GVI67_RS05310	COG1609	Transcriptional regulator
GVI67_RS05330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GVI67_RS05340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GVI67_RS05350	COG0110	maltose O-acetyltransferase activity
GVI67_RS05365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS05375	COG1309	transcriptional regulator
GVI67_RS05380	COG3264	Mechanosensitive ion channel
GVI67_RS05380	COG1196	nuclear chromosome segregation
GVI67_RS05390	COG3923	Primosomal replication protein n
GVI67_RS05395	COG2832	Protein of unknown function (DUF454)
GVI67_RS05400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GVI67_RS05405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GVI67_RS05410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GVI67_RS05415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GVI67_RS05420	COG0326	Molecular chaperone. Has ATPase activity
GVI67_RS05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GVI67_RS05435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI67_RS05440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GVI67_RS05440	COG4651	solute:proton antiporter activity
GVI67_RS05445	COG2223	nitrite transmembrane transporter activity
GVI67_RS05450	COG0737	Belongs to the 5'-nucleotidase family
GVI67_RS05455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GVI67_RS05460	COG3735	TraB family
GVI67_RS05465	COG2217	Heavy metal translocating P-type atpase
GVI67_RS05475	COG1585	Membrane protein implicated in regulation of membrane protease activity
GVI67_RS05480	COG0330	HflC and HflK could
GVI67_RS05490	COG4619	ABC transporter
GVI67_RS05495	COG0390	transport system, permease component
GVI67_RS05500	COG3118	belongs to the thioredoxin family
GVI67_RS05505	COG0300	oxidoreductase activity
GVI67_RS05510	COG2755	lipolytic protein G-D-S-L family
GVI67_RS05515	COG4181	ATPase activity
GVI67_RS05520	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GVI67_RS05535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GVI67_RS05540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GVI67_RS05545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GVI67_RS05550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GVI67_RS05560	COG1988	membrane-bound metal-dependent
GVI67_RS05565	COG1609	Transcriptional regulator
GVI67_RS05570	COG1263	PTS System
GVI67_RS05570	COG2190	(PTS) system
GVI67_RS05570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS05575	COG2501	S4 domain
GVI67_RS05720	COG2246	polysaccharide biosynthetic process
GVI67_RS05750	COG1113	amino acid transport
GVI67_RS05755	COG2211	Major facilitator Superfamily
GVI67_RS05770	COG1609	Transcriptional regulator
GVI67_RS05775	COG0668	transmembrane transport
GVI67_RS05780	COG0477	Major facilitator Superfamily
GVI67_RS05795	COG0778	Nitroreductase
GVI67_RS05800	COG2315	Protein conserved in bacteria
GVI67_RS05815	COG2207	Transcriptional regulator
GVI67_RS05840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GVI67_RS05860	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS05880	COG5499	transcription regulator containing HTH domain
GVI67_RS05945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GVI67_RS05955	COG1121	(ABC) transporter
GVI67_RS05960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI67_RS05965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI67_RS05970	COG2977	Belongs to the P-Pant transferase superfamily
GVI67_RS05975	COG4771	TonB-dependent receptor
GVI67_RS05980	COG2382	esterase
GVI67_RS05985	COG3251	PFAM MbtH domain protein
GVI67_RS05990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GVI67_RS05990	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GVI67_RS05995	COG1120	ATPase activity
GVI67_RS06000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS06005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS06015	COG4592	Periplasmic binding protein
GVI67_RS06020	COG1169	isochorismate synthase
GVI67_RS06025	COG1021	2,3-dihydroxybenzoate-AMP ligase
GVI67_RS06030	COG1535	isochorismatase
GVI67_RS06030	COG3433	isochorismatase activity
GVI67_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS06040	COG2050	protein possibly involved in aromatic compounds catabolism
GVI67_RS06045	COG1966	Carbon starvation protein
GVI67_RS06050	COG2879	small protein
GVI67_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS06070	COG0371	Dehydrogenase
GVI67_RS06075	COG1129	ABC transporter
GVI67_RS06080	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS06095	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GVI67_RS06110	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GVI67_RS06115	COG0235	Class ii aldolase
GVI67_RS06120	COG0436	Aminotransferase
GVI67_RS06125	COG1475	DNA binding
GVI67_RS06130	COG3969	phosphoadenosine phosphosulfate
GVI67_RS06135	COG0583	DNA-binding transcription factor activity
GVI67_RS06155	COG1063	alcohol dehydrogenase
GVI67_RS06160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GVI67_RS06170	COG3719	Belongs to the RNase T2 family
GVI67_RS06175	COG3069	C4-dicarboxylate transmembrane transporter activity
GVI67_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS06200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS06215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GVI67_RS06220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI67_RS06225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GVI67_RS06230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GVI67_RS06235	COG0583	DNA-binding transcription factor activity
GVI67_RS06240	COG0321	lipoyl(octanoyl) transferase activity
GVI67_RS06250	COG1686	Belongs to the peptidase S11 family
GVI67_RS06255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GVI67_RS06260	COG0772	Belongs to the SEDS family
GVI67_RS06265	COG0768	penicillin binding
GVI67_RS06275	COG0799	negative regulation of ribosome biogenesis
GVI67_RS06285	COG1466	dna polymerase III delta subunit
GVI67_RS06300	COG2888	peptidyl-tyrosine sulfation
GVI67_RS06315	COG1957	nucleoside hydrolase
GVI67_RS06320	COG1126	abc transporter atp-binding protein
GVI67_RS06325	COG0765	amino acid transport
GVI67_RS06330	COG0765	amino acid transport
GVI67_RS06350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GVI67_RS06355	COG1702	phosphate starvation-inducible protein PhoH
GVI67_RS06360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GVI67_RS06365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI67_RS06405	COG0367	asparagine synthase
GVI67_RS06410	COG0647	UMP catabolic process
GVI67_RS06415	COG1846	Transcriptional regulator
GVI67_RS06415	COG1940	carbohydrate kinase activity
GVI67_RS06420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GVI67_RS06430	COG1263	PTS System
GVI67_RS06430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS06430	COG2190	(PTS) system
GVI67_RS06435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GVI67_RS06450	COG0735	belongs to the Fur family
GVI67_RS06465	COG0596	Alpha beta hydrolase
GVI67_RS06475	COG0033	Phosphoglucomutase
GVI67_RS06480	COG0531	amino acid
GVI67_RS06485	COG1982	Orn Lys Arg decarboxylase major
GVI67_RS06495	COG0745	RESPONSE REGULATOR receiver
GVI67_RS06500	COG2205	protein histidine kinase activity
GVI67_RS06505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GVI67_RS06510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GVI67_RS06515	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GVI67_RS06535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GVI67_RS06540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GVI67_RS06545	COG1984	allophanate hydrolase subunit 2
GVI67_RS06555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GVI67_RS06560	COG0372	Belongs to the citrate synthase family
GVI67_RS06565	COG2009	succinate dehydrogenase
GVI67_RS06570	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GVI67_RS06575	COG1053	succinate dehydrogenase
GVI67_RS06580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GVI67_RS06585	COG0567	Dehydrogenase, E1 component
GVI67_RS06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
GVI67_RS06595	COG0045	succinate-CoA ligase (ADP-forming) activity
GVI67_RS06600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GVI67_RS06615	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GVI67_RS06620	COG2188	Transcriptional regulator
GVI67_RS06625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS06625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS06625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS06630	COG0383	alpha-mannosidase activity
GVI67_RS06635	COG1271	oxidase subunit
GVI67_RS06640	COG1294	oxidase, subunit
GVI67_RS06645	COG4890	Cyd operon protein YbgT
GVI67_RS06650	COG3790	cyd operon protein YbgE
GVI67_RS06655	COG0824	Thioesterase
GVI67_RS06660	COG0811	peptide transport
GVI67_RS06665	COG0848	biopolymer transport protein
GVI67_RS06670	COG3064	Membrane
GVI67_RS06675	COG0823	Involved in the tonB-independent uptake of proteins
GVI67_RS06680	COG2885	chlorophyll binding
GVI67_RS06685	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GVI67_RS06720	COG3201	nicotinamide mononucleotide transporter
GVI67_RS06725	COG1230	cation diffusion facilitator family transporter
GVI67_RS06735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI67_RS06745	COG2017	converts alpha-aldose to the beta-anomer
GVI67_RS06750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GVI67_RS06755	COG1085	galactose-1-phosphate uridylyltransferase
GVI67_RS06760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GVI67_RS06765	COG1119	ATPase activity
GVI67_RS06770	COG2005	Transcriptional regulator
GVI67_RS06770	COG3585	molybdate ion transport
GVI67_RS06780	COG0725	ABC transporter, periplasmic molybdate-binding protein
GVI67_RS06785	COG4149	molybdate abc transporter
GVI67_RS06795	COG0561	phosphatase activity
GVI67_RS06800	COG2706	6-phosphogluconolactonase activity
GVI67_RS06805	COG4677	pectinesterase activity
GVI67_RS06815	COG0010	Belongs to the arginase family
GVI67_RS06825	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GVI67_RS06830	COG2986	histidine ammonia-lyase
GVI67_RS06835	COG1881	PFAM PEBP family protein
GVI67_RS06840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GVI67_RS06845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GVI67_RS06850	COG0156	8-amino-7-oxononanoate synthase activity
GVI67_RS06855	COG2226	methyltransferase
GVI67_RS06885	COG0521	Mo-molybdopterin cofactor biosynthetic process
GVI67_RS06890	COG0315	cyclic pyranopterin monophosphate synthase activity
GVI67_RS06895	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GVI67_RS06900	COG0314	molybdopterin synthase activity
GVI67_RS06905	COG0670	Belongs to the BI1 family
GVI67_RS06910	COG0392	lysyltransferase activity
GVI67_RS06915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI67_RS06920	COG3568	Endonuclease Exonuclease Phosphatase
GVI67_RS06930	COG0842	Transport permease protein
GVI67_RS06935	COG0842	Transport permease protein
GVI67_RS06940	COG1131	(ABC) transporter
GVI67_RS06945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS06950	COG1309	transcriptional regulator
GVI67_RS06955	COG0513	Belongs to the DEAD box helicase family
GVI67_RS06960	COG1199	ATP-dependent helicase activity
GVI67_RS06980	COG3121	Chaperone
GVI67_RS06985	COG3539	Fimbrial protein
GVI67_RS06990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GVI67_RS07000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GVI67_RS07010	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GVI67_RS07015	COG0668	transmembrane transport
GVI67_RS07020	COG1126	abc transporter atp-binding protein
GVI67_RS07025	COG0765	amino acid transport
GVI67_RS07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS07035	COG0783	Belongs to the Dps family
GVI67_RS07045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GVI67_RS07050	COG2194	sulfuric ester hydrolase activity
GVI67_RS07060	COG1321	iron dependent repressor
GVI67_RS07065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GVI67_RS07070	COG1566	PFAM secretion protein HlyD family protein
GVI67_RS07075	COG2814	Major facilitator Superfamily
GVI67_RS07085	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS07090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS07095	COG2188	Transcriptional regulator
GVI67_RS07100	COG1376	ErfK ybiS ycfS ynhG family protein
GVI67_RS07105	COG0488	(ABC) transporter
GVI67_RS07115	COG2271	Major facilitator Superfamily
GVI67_RS07120	COG1609	Transcriptional regulator
GVI67_RS07130	COG0561	phosphatase activity
GVI67_RS07135	COG1882	Formate acetyltransferase
GVI67_RS07140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI67_RS07145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GVI67_RS07150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GVI67_RS07155	COG0303	'Molybdopterin
GVI67_RS07160	COG1446	asparaginase
GVI67_RS07195	COG2133	pyrroloquinoline quinone binding
GVI67_RS07200	COG0625	glutathione transferase activity
GVI67_RS07205	COG1686	Belongs to the peptidase S11 family
GVI67_RS07210	COG1349	DNA-binding transcription factor activity
GVI67_RS07215	COG0671	phosphoesterase, PA-phosphatase related
GVI67_RS07225	COG2814	Major facilitator Superfamily
GVI67_RS07230	COG0561	phosphatase activity
GVI67_RS07235	COG0738	Major facilitator superfamily
GVI67_RS07240	COG3226	Transcriptional regulator
GVI67_RS07245	COG1393	Belongs to the ArsC family
GVI67_RS07275	COG0778	Nitroreductase
GVI67_RS07290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GVI67_RS07295	COG3842	ATPase activity
GVI67_RS07300	COG1176	ABC-type spermidine putrescine transport system, permease component I
GVI67_RS07305	COG1177	transmembrane transport
GVI67_RS07315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GVI67_RS07320	COG0745	RESPONSE REGULATOR receiver
GVI67_RS07325	COG5002	protein histidine kinase activity
GVI67_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS07335	COG4160	amino acid transport
GVI67_RS07340	COG4215	(ABC) transporter
GVI67_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS07350	COG1126	abc transporter atp-binding protein
GVI67_RS07360	COG0393	Putative heavy-metal-binding
GVI67_RS07365	COG3023	N-Acetylmuramoyl-L-alanine amidase
GVI67_RS07390	COG1450	Type ii and iii secretion system protein
GVI67_RS07395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI67_RS07400	COG1459	type II secretion system
GVI67_RS07405	COG2165	general secretion pathway protein
GVI67_RS07415	COG2165	general secretion pathway protein
GVI67_RS07440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GVI67_RS07460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI67_RS07465	COG0702	epimerase
GVI67_RS07470	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GVI67_RS07475	COG0028	Belongs to the TPP enzyme family
GVI67_RS07480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI67_RS07485	COG1151	hydroxylamine reductase activity
GVI67_RS07490	COG2431	L-lysine efflux transmembrane transporter activity
GVI67_RS07500	COG3593	DNA synthesis involved in DNA repair
GVI67_RS07505	COG2990	Protein conserved in bacteria
GVI67_RS07510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS07520	COG1278	Cold shock
GVI67_RS07525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GVI67_RS07530	COG0542	response to heat
GVI67_RS07540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GVI67_RS07545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GVI67_RS07550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GVI67_RS07555	COG4988	ABC transporter
GVI67_RS07560	COG0492	ferredoxin-NADP+ reductase activity
GVI67_RS07570	COG1674	ftsk spoiiie
GVI67_RS07570	COG1178	ABC-type Fe3 transport system permease component
GVI67_RS07575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GVI67_RS07580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GVI67_RS07585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GVI67_RS07590	COG0243	molybdopterin cofactor binding
GVI67_RS07595	COG0437	4 iron, 4 sulfur cluster binding
GVI67_RS07600	COG3302	dmso reductase anchor subunit
GVI67_RS07605	COG0477	Major facilitator Superfamily
GVI67_RS07615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GVI67_RS07620	COG1882	Formate acetyltransferase
GVI67_RS07625	COG2116	formate transmembrane transporter activity
GVI67_RS07630	COG1944	ATP diphosphatase activity
GVI67_RS07635	COG2323	membrane
GVI67_RS07640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GVI67_RS07645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GVI67_RS07650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GVI67_RS07655	COG0539	negative regulation of cytoplasmic translation
GVI67_RS07660	COG0776	regulation of translation
GVI67_RS07665	COG0658	competence protein
GVI67_RS07665	COG2333	competence protein COMEC
GVI67_RS07670	COG1132	(ABC) transporter
GVI67_RS07680	COG3214	Protein conserved in bacteria
GVI67_RS07685	COG2835	tetraacyldisaccharide 4'-kinase activity
GVI67_RS07690	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GVI67_RS07695	COG3173	Aminoglycoside phosphotransferase
GVI67_RS07700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GVI67_RS07705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GVI67_RS07715	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GVI67_RS07720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GVI67_RS07725	COG2989	Protein conserved in bacteria
GVI67_RS07730	COG3108	Peptidase M15
GVI67_RS07735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GVI67_RS07740	COG1448	Aminotransferase
GVI67_RS07750	COG0017	Asparaginyl-tRNA synthetase
GVI67_RS07755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GVI67_RS07760	COG0308	aminopeptidase N
GVI67_RS07770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GVI67_RS07775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS07780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GVI67_RS07785	COG0431	NADPH-dependent FMN reductase
GVI67_RS07790	COG0167	dihydroorotate dehydrogenase activity
GVI67_RS07800	COG0633	Ferredoxin
GVI67_RS07800	COG3217	Mosc domain protein beta barrel domain protein
GVI67_RS07805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GVI67_RS07805	COG0116	Belongs to the methyltransferase superfamily
GVI67_RS07810	COG0488	(ABC) transporter
GVI67_RS07815	COG2995	paraquat-inducible protein a
GVI67_RS07820	COG3008	intermembrane lipid transfer
GVI67_RS07820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GVI67_RS07825	COG3009	Protein conserved in bacteria
GVI67_RS07830	COG3130	regulation of translation
GVI67_RS07840	COG1067	ATP-dependent peptidase activity
GVI67_RS07845	COG3120	sequence-specific DNA binding
GVI67_RS07855	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
GVI67_RS07865	COG1289	transmembrane transporter activity
GVI67_RS07870	COG3304	Inner membrane component domain
GVI67_RS07875	COG0210	DNA helicase
GVI67_RS07880	COG1803	Methylglyoxal synthase
GVI67_RS07885	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GVI67_RS07890	COG1832	CoA-binding protein
GVI67_RS07900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GVI67_RS07905	COG1254	Belongs to the acylphosphatase family
GVI67_RS07915	COG0670	Belongs to the BI1 family
GVI67_RS07935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS07945	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GVI67_RS07945	COG3264	Mechanosensitive ion channel
GVI67_RS07955	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS07970	COG2239	Acts as a magnesium transporter
GVI67_RS07975	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS07995	COG3729	General stress protein
GVI67_RS08015	COG2233	PERMEase
GVI67_RS08020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GVI67_RS08025	COG0778	Nitroreductase
GVI67_RS08030	COG2267	carboxylic ester hydrolase activity
GVI67_RS08035	COG0251	oxidation-reduction process
GVI67_RS08040	COG1335	isochorismatase
GVI67_RS08045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS08050	COG1309	transcriptional regulator
GVI67_RS08060	COG0506	proline dehydrogenase activity
GVI67_RS08060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI67_RS08060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GVI67_RS08065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GVI67_RS08075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GVI67_RS08095	COG1702	phosphate starvation-inducible protein PhoH
GVI67_RS08100	COG1115	amino acid carrier protein
GVI67_RS08110	COG1335	isochorismatase
GVI67_RS08120	COG0583	DNA-binding transcription factor activity
GVI67_RS08130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GVI67_RS08135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GVI67_RS08140	COG3381	protein complex oligomerization
GVI67_RS08215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GVI67_RS08230	COG2943	transferase activity, transferring hexosyl groups
GVI67_RS08235	COG5645	(Lipo)protein
GVI67_RS08250	COG1560	Kdo2-lipid A biosynthetic process
GVI67_RS08255	COG1054	Belongs to the UPF0176 family
GVI67_RS08260	COG2353	YceI-like domain
GVI67_RS08265	COG3038	cytochrome b561
GVI67_RS08290	COG0418	dihydroorotase activity
GVI67_RS08300	COG0477	Major facilitator Superfamily
GVI67_RS08305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI67_RS08310	COG3132	Protein of unknown function, DUF480
GVI67_RS08345	COG1558	bacterial-type flagellum-dependent cell motility
GVI67_RS08365	COG4786	Flagellar basal body rod
GVI67_RS08385	COG1256	bacterial-type flagellum assembly
GVI67_RS08395	COG2814	Major facilitator Superfamily
GVI67_RS08400	COG0583	DNA-binding transcription factor activity
GVI67_RS08405	COG1530	ribonuclease E activity
GVI67_RS08410	COG0564	pseudouridine synthase activity
GVI67_RS08415	COG0424	maF-like protein
GVI67_RS08425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GVI67_RS08430	COG0416	fatty acid biosynthetic process
GVI67_RS08435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GVI67_RS08450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GVI67_RS08455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI67_RS08460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GVI67_RS08465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GVI67_RS08470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GVI67_RS08475	COG0470	DNA polymerase III
GVI67_RS08480	COG0084	hydrolase, TatD family'
GVI67_RS08490	COG4773	Receptor
GVI67_RS08495	COG0537	adenosine 5'-monophosphoramidase activity
GVI67_RS08500	COG5633	Lipoprotein
GVI67_RS08505	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
GVI67_RS08520	COG3150	esterase
GVI67_RS08525	COG1252	NADH dehydrogenase
GVI67_RS08530	COG3134	Outer membrane lipoprotein
GVI67_RS08535	COG1309	transcriptional regulator
GVI67_RS08545	COG1376	ErfK ybiS ycfS ynhG family protein
GVI67_RS08545	COG1388	LysM domain
GVI67_RS08550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GVI67_RS08555	COG4763	Acyl-transferase
GVI67_RS08560	COG4591	ABC-type transport system involved in lipoprotein release permease component
GVI67_RS08565	COG1136	(ABC) transporter
GVI67_RS08570	COG4591	ABC-type transport system involved in lipoprotein release permease component
GVI67_RS08580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GVI67_RS08610	COG1943	Transposase
GVI67_RS08615	COG2850	peptidyl-arginine hydroxylation
GVI67_RS08620	COG2205	protein histidine kinase activity
GVI67_RS08635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GVI67_RS08640	COG2915	High frequency lysogenization protein hflD homolog
GVI67_RS08655	COG1187	pseudouridine synthase activity
GVI67_RS08660	COG0538	isocitrate dehydrogenase activity
GVI67_RS08670	COG5001	Diguanylate cyclase
GVI67_RS08680	COG2261	transglycosylase associated protein
GVI67_RS08695	COG2199	diguanylate cyclase activity
GVI67_RS08695	COG2203	Gaf domain
GVI67_RS08700	COG3042	response to heat
GVI67_RS08710	COG3189	MarR family transcriptional regulator
GVI67_RS08715	COG0504	CTP synthase activity
GVI67_RS08720	COG2807	transmembrane transport
GVI67_RS08725	COG2207	Transcriptional regulator
GVI67_RS08740	COG2211	Major facilitator Superfamily
GVI67_RS08745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GVI67_RS08750	COG2718	Belongs to the UPF0229 family
GVI67_RS08755	COG2766	serine protein kinase
GVI67_RS08760	COG3713	MltA-interacting MipA family protein
GVI67_RS08780	COG3139	Protein of unknown function (DUF1315)
GVI67_RS08790	COG1335	isochorismatase
GVI67_RS08795	COG0252	asparaginase activity
GVI67_RS08800	COG0616	signal peptide processing
GVI67_RS08805	COG0778	Nitroreductase
GVI67_RS08810	COG0709	Synthesizes selenophosphate from selenide and ATP
GVI67_RS08815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GVI67_RS08825	COG0641	radical SAM
GVI67_RS08830	COG2190	(PTS) system
GVI67_RS08830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS08830	COG1263	PTS System
GVI67_RS08845	COG1737	Transcriptional regulator
GVI67_RS08850	COG2149	membrane
GVI67_RS08870	COG0494	nUDIX hydrolase
GVI67_RS08875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI67_RS08880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GVI67_RS08885	COG2897	thiosulfate sulfurtransferase activity
GVI67_RS08890	COG4136	ATPase activity
GVI67_RS08895	COG4135	transport system, permease component
GVI67_RS08900	COG4134	Bacterial extracellular solute-binding protein
GVI67_RS08910	COG0708	Exodeoxyribonuclease III
GVI67_RS08920	COG3138	arginine N-succinyltransferase
GVI67_RS08925	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS08930	COG3724	N-succinylarginine dihydrolase activity
GVI67_RS08940	COG3678	ATP-independent chaperone mediated protein folding
GVI67_RS08950	COG0322	excinuclease ABC activity
GVI67_RS08960	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI67_RS08965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS08970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS08975	COG1447	Phosphotransferase system cellobiose-specific component IIA
GVI67_RS08980	COG2169	Transcriptional regulator
GVI67_RS08980	COG1917	Cupin 2, conserved barrel domain protein
GVI67_RS08985	COG1486	melibiose metabolic process
GVI67_RS08990	COG3394	polysaccharide catabolic process
GVI67_RS09005	COG1823	symporter activity
GVI67_RS09010	COG1988	membrane-bound metal-dependent
GVI67_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS09020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI67_RS09030	COG3001	Fructosamine kinase
GVI67_RS09040	COG1105	Belongs to the carbohydrate kinase PfkB family
GVI67_RS09045	COG3137	Salt-induced outer membrane protein
GVI67_RS09090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GVI67_RS09095	COG0072	phenylalanine-tRNA ligase activity
GVI67_RS09095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GVI67_RS09100	COG0776	regulation of translation
GVI67_RS09110	COG0386	Belongs to the glutathione peroxidase family
GVI67_RS09120	COG0791	NLP P60 protein
GVI67_RS09130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GVI67_RS09140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS09145	COG4558	Periplasmic binding protein
GVI67_RS09150	COG3720	iron ion transport
GVI67_RS09160	COG4256	Hemin uptake protein
GVI67_RS09165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI67_RS09170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GVI67_RS09175	COG0574	Belongs to the PEP-utilizing enzyme family
GVI67_RS09175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GVI67_RS09180	COG2211	Major facilitator Superfamily
GVI67_RS09185	COG1472	Belongs to the glycosyl hydrolase 3 family
GVI67_RS09195	COG0628	permease
GVI67_RS09200	COG0277	FAD linked oxidase domain protein
GVI67_RS09200	COG0247	lactate metabolic process
GVI67_RS09205	COG2050	protein possibly involved in aromatic compounds catabolism
GVI67_RS09215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI67_RS09230	COG3121	Chaperone
GVI67_RS09245	COG3539	Fimbrial protein
GVI67_RS09270	COG2200	EAL domain
GVI67_RS09275	COG0789	Transcriptional regulator
GVI67_RS09280	COG0316	Belongs to the HesB IscA family
GVI67_RS09285	COG0719	Fe-S assembly protein
GVI67_RS09290	COG0396	ATPase activity
GVI67_RS09295	COG0719	Fe-S assembly protein
GVI67_RS09300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GVI67_RS09305	COG2166	iron-sulfur cluster assembly
GVI67_RS09310	COG1376	ErfK ybiS ycfS ynhG family protein
GVI67_RS09330	COG2011	ABC-type metal ion transport system permease component
GVI67_RS09335	COG1464	Belongs to the NlpA lipoprotein family
GVI67_RS09345	COG0765	amino acid transport
GVI67_RS09350	COG0765	amino acid transport
GVI67_RS09360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS09380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GVI67_RS09390	COG4529	Protein conserved in bacteria
GVI67_RS09420	COG0307	riboflavin synthase, alpha
GVI67_RS09425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GVI67_RS09430	COG2814	Major facilitator Superfamily
GVI67_RS09435	COG0583	DNA-binding transcription factor activity
GVI67_RS09450	COG2814	Major facilitator Superfamily
GVI67_RS09460	COG0791	NLP P60 protein
GVI67_RS09465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GVI67_RS09475	COG0346	lactoylglutathione lyase activity
GVI67_RS09480	COG1902	pentaerythritol trinitrate reductase activity
GVI67_RS09485	COG1309	transcriptional regulator
GVI67_RS09490	COG2194	sulfuric ester hydrolase activity
GVI67_RS09495	COG3313	Fe-S protein
GVI67_RS09500	COG4989	oxidoreductase activity
GVI67_RS09505	COG2032	superoxide dismutase activity
GVI67_RS09510	COG1289	transmembrane transporter activity
GVI67_RS09515	COG1566	PFAM secretion protein HlyD family protein
GVI67_RS09530	COG3706	GGDEF domain
GVI67_RS09540	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GVI67_RS09545	COG3895	Periplasmic Protein
GVI67_RS09550	COG0259	pyridoxamine-phosphate oxidase activity
GVI67_RS09555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GVI67_RS09560	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GVI67_RS09565	COG0625	glutathione transferase activity
GVI67_RS09570	COG3104	oligopeptide transport
GVI67_RS09575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GVI67_RS09625	COG0673	inositol 2-dehydrogenase activity
GVI67_RS09630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GVI67_RS09635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GVI67_RS09640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS09640	COG1263	PTS System
GVI67_RS09645	COG1609	Transcriptional regulator
GVI67_RS09650	COG5339	Protein conserved in bacteria
GVI67_RS09655	COG1482	cell wall glycoprotein biosynthetic process
GVI67_RS09660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI67_RS09660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI67_RS09675	COG2205	protein histidine kinase activity
GVI67_RS09700	COG1278	Cold shock
GVI67_RS09710	COG0745	RESPONSE REGULATOR receiver
GVI67_RS09715	COG3136	membrane protein required for alginate biosynthesis
GVI67_RS09720	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS09725	COG0531	amino acid
GVI67_RS09735	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GVI67_RS09740	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GVI67_RS09745	COG0668	transmembrane transport
GVI67_RS09750	COG0589	response to stress
GVI67_RS09760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GVI67_RS09765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GVI67_RS09770	COG1473	amidohydrolase
GVI67_RS09780	COG0583	DNA-binding transcription factor activity
GVI67_RS09785	COG2840	Smr protein MutS2
GVI67_RS09795	COG0667	Aldo Keto reductase
GVI67_RS09810	COG4993	Dehydrogenase
GVI67_RS09850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GVI67_RS09855	COG1403	HNH endonuclease
GVI67_RS09860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS09870	COG0628	permease
GVI67_RS09875	COG2076	Multidrug Resistance protein
GVI67_RS09880	COG2076	Multidrug Resistance protein
GVI67_RS09885	COG3591	Belongs to the peptidase S1B family
GVI67_RS09895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GVI67_RS09915	COG2814	Major facilitator Superfamily
GVI67_RS09920	COG0583	DNA-binding transcription factor activity
GVI67_RS09925	COG1940	carbohydrate kinase activity
GVI67_RS09930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GVI67_RS10000	COG3141	response to X-ray
GVI67_RS10010	COG3302	dmso reductase anchor subunit
GVI67_RS10020	COG0243	molybdopterin cofactor binding
GVI67_RS10075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI67_RS10085	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS10090	COG1063	alcohol dehydrogenase
GVI67_RS10095	COG0477	Major facilitator Superfamily
GVI67_RS10100	COG0246	Mannitol dehydrogenase
GVI67_RS10110	COG0589	response to stress
GVI67_RS10115	COG1802	Transcriptional regulator
GVI67_RS10120	COG4221	oxidoreductase activity
GVI67_RS10135	COG0814	amino acid
GVI67_RS10145	COG4993	Dehydrogenase
GVI67_RS10170	COG0745	RESPONSE REGULATOR receiver
GVI67_RS10195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GVI67_RS10200	COG2911	Protein conserved in bacteria
GVI67_RS10210	COG3784	Protein of unknown function (DUF1318)
GVI67_RS10215	COG2207	Transcriptional regulator
GVI67_RS10220	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS10225	COG4251	negative regulation of phosphorylation
GVI67_RS10225	COG3706	GGDEF domain
GVI67_RS10225	COG2203	Gaf domain
GVI67_RS10225	COG5001	Diguanylate cyclase
GVI67_RS10230	COG3733	amine oxidase
GVI67_RS10235	COG2030	dehydratase
GVI67_RS10235	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS10240	COG3396	Phenylacetate-CoA oxygenase
GVI67_RS10245	COG3460	Phenylacetate-CoA oxygenase
GVI67_RS10250	COG3396	Phenylacetate-CoA oxygenase
GVI67_RS10255	COG2151	metal-sulfur cluster biosynthetic enzyme
GVI67_RS10260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI67_RS10265	COG1024	Enoyl-CoA hydratase
GVI67_RS10270	COG1024	Enoyl-CoA hydratase
GVI67_RS10275	COG1250	3-hydroxyacyl-CoA dehydrogenase
GVI67_RS10280	COG2050	protein possibly involved in aromatic compounds catabolism
GVI67_RS10285	COG0183	Belongs to the thiolase family
GVI67_RS10290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GVI67_RS10295	COG3327	negative regulation of DNA-templated transcription, initiation
GVI67_RS10300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GVI67_RS10305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GVI67_RS10325	COG0300	oxidoreductase activity
GVI67_RS10340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GVI67_RS10385	COG3122	Protein conserved in bacteria
GVI67_RS10390	COG0564	pseudouridine synthase activity
GVI67_RS10400	COG1643	Atp-dependent helicase
GVI67_RS10405	COG4122	O-methyltransferase activity
GVI67_RS10410	COG1538	Outer membrane efflux protein
GVI67_RS10425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GVI67_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS10440	COG3038	cytochrome b561
GVI67_RS10445	COG0673	inositol 2-dehydrogenase activity
GVI67_RS10450	COG1349	DNA-binding transcription factor activity
GVI67_RS10465	COG2274	protein secretion by the type I secretion system
GVI67_RS10515	COG0840	transmembrane signaling receptor activity
GVI67_RS10530	COG0513	Belongs to the DEAD box helicase family
GVI67_RS10550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI67_RS10555	COG1013	pyruvate-flavodoxin oxidoreductase activity
GVI67_RS10555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GVI67_RS10555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI67_RS10555	COG0674	pyruvate-flavodoxin oxidoreductase activity
GVI67_RS10560	COG3042	response to heat
GVI67_RS10565	COG3187	Heat shock protein
GVI67_RS10575	COG1294	oxidase, subunit
GVI67_RS10580	COG1271	oxidase subunit
GVI67_RS10590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GVI67_RS10595	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS10605	COG3615	Tellurite resistance protein tehB
GVI67_RS10610	COG3615	Tellurite resistance protein tehB
GVI67_RS10640	COG0747	negative chemotaxis
GVI67_RS10650	COG3238	Protein conserved in bacteria
GVI67_RS10655	COG1247	-acetyltransferase
GVI67_RS10665	COG2130	NADP-dependent
GVI67_RS10670	COG1802	Transcriptional regulator
GVI67_RS10675	COG4772	TonB-dependent receptor
GVI67_RS10700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GVI67_RS10705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS10710	COG1473	amidohydrolase
GVI67_RS10715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS10720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GVI67_RS10735	COG1126	abc transporter atp-binding protein
GVI67_RS10745	COG0625	glutathione transferase activity
GVI67_RS10750	COG1942	4-Oxalocrotonate Tautomerase
GVI67_RS10755	COG1560	Kdo2-lipid A biosynthetic process
GVI67_RS10765	COG0640	Transcriptional regulator
GVI67_RS10770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GVI67_RS10785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GVI67_RS10790	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GVI67_RS10795	COG2181	nitrate reductase activity
GVI67_RS10800	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GVI67_RS10805	COG1140	nitrate reductase beta subunit
GVI67_RS10810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GVI67_RS10845	COG0437	4 iron, 4 sulfur cluster binding
GVI67_RS10850	COG2864	formate dehydrogenase
GVI67_RS10870	COG2814	Major facilitator Superfamily
GVI67_RS10875	COG1064	alcohol dehydrogenase
GVI67_RS10880	COG0488	(ABC) transporter
GVI67_RS10885	COG0281	malic enzyme
GVI67_RS10915	COG1764	response to oxidative stress
GVI67_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS10930	COG4608	Belongs to the ABC transporter superfamily
GVI67_RS10935	COG0444	Belongs to the ABC transporter superfamily
GVI67_RS10940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GVI67_RS10945	COG0601	transmembrane transport
GVI67_RS10950	COG0747	negative chemotaxis
GVI67_RS10955	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GVI67_RS10970	COG2200	EAL domain
GVI67_RS11000	COG0840	transmembrane signaling receptor activity
GVI67_RS11015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI67_RS11020	COG1649	PFAM Uncharacterised BCR, COG1649
GVI67_RS11025	COG4628	conserved protein (DUF2132)
GVI67_RS11030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GVI67_RS11035	COG0583	DNA-binding transcription factor activity
GVI67_RS11045	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS11055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GVI67_RS11090	COG2814	Major facilitator Superfamily
GVI67_RS11140	COG0714	Associated with various cellular activities
GVI67_RS11145	COG0641	radical SAM
GVI67_RS11165	COG2067	long-chain fatty acid transport protein
GVI67_RS11185	COG0583	DNA-binding transcription factor activity
GVI67_RS11200	COG0583	DNA-binding transcription factor activity
GVI67_RS11205	COG2076	Multidrug Resistance protein
GVI67_RS11215	COG0110	maltose O-acetyltransferase activity
GVI67_RS11235	COG1349	DNA-binding transcription factor activity
GVI67_RS11240	COG0494	nUDIX hydrolase
GVI67_RS11245	COG4106	trans-aconitate 2-methyltransferase activity
GVI67_RS11265	COG0596	Alpha beta hydrolase
GVI67_RS11290	COG3781	membrane
GVI67_RS11295	COG0246	Mannitol dehydrogenase
GVI67_RS11305	COG3706	GGDEF domain
GVI67_RS11315	COG2066	Belongs to the glutaminase family
GVI67_RS11325	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS11330	COG0583	DNA-binding transcription factor activity
GVI67_RS11345	COG2814	Major facilitator Superfamily
GVI67_RS11355	COG1846	Transcriptional regulator
GVI67_RS11370	COG0697	spore germination
GVI67_RS11375	COG2814	Major facilitator Superfamily
GVI67_RS11380	COG3443	Belongs to the bacterial solute-binding protein 9 family
GVI67_RS11390	COG1129	ABC transporter
GVI67_RS11415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GVI67_RS11440	COG0826	peptidase U32
GVI67_RS11445	COG1396	sequence-specific DNA binding
GVI67_RS11450	COG3135	benzoate transporter
GVI67_RS11470	COG0747	negative chemotaxis
GVI67_RS11475	COG2195	Cleaves the N-terminal amino acid of tripeptides
GVI67_RS11480	COG0500	methyltransferase
GVI67_RS11485	COG1275	C4-dicarboxylate transporter malic acid transport protein
GVI67_RS11490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GVI67_RS11495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI67_RS11500	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GVI67_RS11510	COG0436	Aminotransferase
GVI67_RS11520	COG2272	Belongs to the type-B carboxylesterase lipase family
GVI67_RS11525	COG5383	Protein conserved in bacteria
GVI67_RS11530	COG0583	DNA-binding transcription factor activity
GVI67_RS11535	COG0840	transmembrane signaling receptor activity
GVI67_RS11590	COG4166	transmembrane transport
GVI67_RS11595	COG2866	Carboxypeptidase
GVI67_RS11600	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS11605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GVI67_RS11615	COG3768	UPF0283 membrane protein
GVI67_RS11620	COG3106	COG3106 Predicted ATPase
GVI67_RS11625	COG1609	Transcriptional regulator
GVI67_RS11635	COG3842	ATPase activity
GVI67_RS11640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI67_RS11645	COG1554	hydrolase, family 65, central catalytic
GVI67_RS11650	COG0673	inositol 2-dehydrogenase activity
GVI67_RS11655	COG1082	Xylose isomerase domain protein TIM barrel
GVI67_RS11660	COG1063	alcohol dehydrogenase
GVI67_RS11665	COG0395	ABC-type sugar transport system, permease component
GVI67_RS11670	COG1175	transmembrane transport
GVI67_RS11675	COG1653	transport
GVI67_RS11680	COG0366	Alpha amylase catalytic
GVI67_RS11690	COG1983	PspC domain protein
GVI67_RS11700	COG1842	Phage shock protein A
GVI67_RS11705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GVI67_RS11720	COG4171	peptide transport system, permease
GVI67_RS11730	COG4172	Belongs to the ABC transporter superfamily
GVI67_RS11740	COG0251	oxidation-reduction process
GVI67_RS11745	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GVI67_RS11750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI67_RS11750	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GVI67_RS11760	COG5001	Diguanylate cyclase
GVI67_RS11765	COG1024	Enoyl-CoA hydratase
GVI67_RS11775	COG1349	DNA-binding transcription factor activity
GVI67_RS11785	COG0023	Translation Initiation Factor
GVI67_RS11790	COG0284	orotidine-5'-phosphate decarboxylase activity
GVI67_RS11795	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GVI67_RS11800	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GVI67_RS11805	COG0671	phosphoesterase, PA-phosphatase related
GVI67_RS11815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GVI67_RS11845	COG0616	signal peptide processing
GVI67_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS11855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GVI67_RS11865	COG0009	L-threonylcarbamoyladenylate synthase
GVI67_RS11900	COG0159	tryptophan synthase activity
GVI67_RS11905	COG2391	methyltransferase activity
GVI67_RS11910	COG0425	Belongs to the sulfur carrier protein TusA family
GVI67_RS11920	COG3047	cAMP biosynthetic process
GVI67_RS11925	COG0727	PFAM Uncharacterised protein family (UPF0153)
GVI67_RS11955	COG2350	Protein conserved in bacteria
GVI67_RS11960	COG1280	lysine exporter protein (LysE YggA)
GVI67_RS11980	COG3099	Belongs to the UPF0263 family
GVI67_RS11985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GVI67_RS11990	COG4608	Belongs to the ABC transporter superfamily
GVI67_RS11995	COG0444	Belongs to the ABC transporter superfamily
GVI67_RS12005	COG0601	transmembrane transport
GVI67_RS12015	COG2095	MarC family integral membrane protein
GVI67_RS12020	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS12020	COG1454	alcohol dehydrogenase
GVI67_RS12025	COG1435	thymidine kinase activity
GVI67_RS12035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GVI67_RS12040	COG0745	RESPONSE REGULATOR receiver
GVI67_RS12045	COG1752	Esterase of the alpha-beta hydrolase superfamily
GVI67_RS12050	COG3012	SEC-C Motif Domain Protein
GVI67_RS12055	COG0788	formyltetrahydrofolate deformylase activity
GVI67_RS12075	COG2181	nitrate reductase activity
GVI67_RS12080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GVI67_RS12085	COG1140	nitrate reductase beta subunit
GVI67_RS12090	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GVI67_RS12095	COG2223	nitrite transmembrane transporter activity
GVI67_RS12100	COG3850	Histidine kinase
GVI67_RS12105	COG2197	response regulator
GVI67_RS12110	COG4932	domain protein
GVI67_RS12115	COG0243	molybdopterin cofactor binding
GVI67_RS12120	COG2146	nitrite reductase [NAD(P)H] activity
GVI67_RS12120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GVI67_RS12125	COG1116	anion transmembrane transporter activity
GVI67_RS12135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GVI67_RS12140	COG3707	response regulator
GVI67_RS12145	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GVI67_RS12150	COG0840	transmembrane signaling receptor activity
GVI67_RS12160	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GVI67_RS12165	COG4572	Cation transport regulator
GVI67_RS12170	COG0387	Pfam Sodium calcium exchanger
GVI67_RS12175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GVI67_RS12200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GVI67_RS12210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GVI67_RS12220	COG0659	secondary active sulfate transmembrane transporter activity
GVI67_RS12235	COG0193	aminoacyl-tRNA hydrolase activity
GVI67_RS12240	COG0012	GTP binding
GVI67_RS12270	COG3209	COG3209 Rhs family protein
GVI67_RS12300	COG3209	COG3209 Rhs family protein
GVI67_RS12325	COG4104	PAAR repeat-containing protein
GVI67_RS12350	COG0515	serine threonine protein kinase
GVI67_RS12465	COG4977	sequence-specific DNA binding
GVI67_RS12470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GVI67_RS12485	COG4774	siderophore transport
GVI67_RS12495	COG0741	lytic transglycosylase activity
GVI67_RS12500	COG1619	proteins homologs of microcin C7 resistance protein MccF
GVI67_RS12505	COG3263	regulation of cellular component size
GVI67_RS12510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GVI67_RS12515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GVI67_RS12520	COG2719	SpoVR family
GVI67_RS12530	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GVI67_RS12540	COG2983	Belongs to the UPF0260 family
GVI67_RS12545	COG0179	Fumarylacetoacetate (FAA) hydrolase
GVI67_RS12555	COG0850	regulation of cytokinetic process
GVI67_RS12560	COG2894	cell division
GVI67_RS12565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GVI67_RS12570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GVI67_RS12575	COG0318	PFAM AMP-dependent synthetase and ligase
GVI67_RS12580	COG3065	identical protein binding
GVI67_RS12585	COG1214	PFAM Peptidase M22, glycoprotease
GVI67_RS12590	COG1199	ATP-dependent helicase activity
GVI67_RS12595	COG0251	oxidation-reduction process
GVI67_RS12610	COG0494	nUDIX hydrolase
GVI67_RS12615	COG1760	l-serine dehydratase
GVI67_RS12620	COG2200	EAL domain
GVI67_RS12625	COG1253	flavin adenine dinucleotide binding
GVI67_RS12630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS12630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS12635	COG3715	PTS system
GVI67_RS12640	COG3716	PTS system mannose fructose sorbose family IID component
GVI67_RS12645	COG4811	Protein of unknown function (DUF986)
GVI67_RS12650	COG1971	Probably functions as a manganese efflux pump
GVI67_RS12655	COG2226	methyltransferase
GVI67_RS12660	COG0768	penicillin binding
GVI67_RS12690	COG1414	Transcriptional regulator
GVI67_RS12695	COG2814	Major facilitator Superfamily
GVI67_RS12700	COG0501	Belongs to the peptidase M48B family
GVI67_RS12715	COG1956	GAF domain-containing protein
GVI67_RS12720	COG2995	paraquat-inducible protein a
GVI67_RS12725	COG3008	intermembrane lipid transfer
GVI67_RS12730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GVI67_RS12730	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GVI67_RS12745	COG2990	Protein conserved in bacteria
GVI67_RS12760	COG1276	copper resistance
GVI67_RS12765	COG2372	response to copper ion
GVI67_RS12775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GVI67_RS12780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GVI67_RS12785	COG1770	oligopeptidase
GVI67_RS12790	COG2979	Protein of unknown function (DUF533)
GVI67_RS12830	COG0800	Aldolase
GVI67_RS12835	COG0129	dihydroxy-acid dehydratase activity
GVI67_RS12840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GVI67_RS12845	COG1737	Transcriptional regulator
GVI67_RS12855	COG1560	Kdo2-lipid A biosynthetic process
GVI67_RS12860	COG0739	heme binding
GVI67_RS12865	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GVI67_RS12875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI67_RS12880	COG2255	four-way junction helicase activity
GVI67_RS12885	COG0632	four-way junction helicase activity
GVI67_RS12900	COG0494	nUDIX hydrolase
GVI67_RS12910	COG1335	isochorismatase
GVI67_RS12915	COG1801	Protein of unknown function DUF72
GVI67_RS12920	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GVI67_RS12925	COG2226	methyltransferase
GVI67_RS12930	COG0500	methyltransferase
GVI67_RS12935	COG3142	Participates in the control of copper homeostasis
GVI67_RS12940	COG3102	Protein conserved in bacteria
GVI67_RS12945	COG0018	arginyl-trna synthetase
GVI67_RS12950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GVI67_RS12980	COG0745	RESPONSE REGULATOR receiver
GVI67_RS12995	COG0840	transmembrane signaling receptor activity
GVI67_RS13030	COG1301	dicarboxylic acid transport
GVI67_RS13070	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GVI67_RS13080	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS13090	COG1879	ABC-type sugar transport system periplasmic component
GVI67_RS13100	COG1528	Iron-storage protein
GVI67_RS13105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GVI67_RS13135	COG1528	Iron-storage protein
GVI67_RS13140	COG0814	amino acid
GVI67_RS13145	COG3318	Belongs to the UPF0149 family
GVI67_RS13145	COG3012	SEC-C Motif Domain Protein
GVI67_RS13180	COG0583	DNA-binding transcription factor activity
GVI67_RS13210	COG2197	response regulator
GVI67_RS13220	COG2197	response regulator
GVI67_RS13225	COG1126	abc transporter atp-binding protein
GVI67_RS13230	COG0765	amino acid transport
GVI67_RS13240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS13260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GVI67_RS13265	COG1516	flagellar protein fliS
GVI67_RS13275	COG0366	Alpha amylase catalytic
GVI67_RS13285	COG1677	Flagellar hook-basal body complex protein FliE
GVI67_RS13295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GVI67_RS13305	COG1157	protein secretion by the type III secretion system
GVI67_RS13345	COG1987	bacterial-type flagellum assembly
GVI67_RS13355	COG2197	response regulator
GVI67_RS13380	COG5475	Uncharacterized small protein (DUF2158)
GVI67_RS13385	COG2354	Protein conserved in bacteria
GVI67_RS13390	COG0697	spore germination
GVI67_RS13395	COG3727	T/G mismatch-specific endonuclease activity
GVI67_RS13400	COG0270	DNA (cytosine-5-)-methyltransferase activity
GVI67_RS13405	COG1418	mRNA catabolic process
GVI67_RS13410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI67_RS13420	COG3290	protein histidine kinase activity
GVI67_RS13425	COG4565	transcriptional regulatory protein
GVI67_RS13445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI67_RS13445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GVI67_RS13470	COG0583	DNA-binding transcription factor activity
GVI67_RS13520	COG0737	Belongs to the 5'-nucleotidase family
GVI67_RS13540	COG1376	ErfK ybiS ycfS ynhG family protein
GVI67_RS13545	COG0477	Major facilitator Superfamily
GVI67_RS13550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GVI67_RS13560	COG0534	Mate efflux family protein
GVI67_RS13575	COG1289	transmembrane transporter activity
GVI67_RS13580	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GVI67_RS13590	COG2925	Exonuclease
GVI67_RS13595	COG0531	amino acid
GVI67_RS13605	COG0583	DNA-binding transcription factor activity
GVI67_RS13610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI67_RS13620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GVI67_RS13630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GVI67_RS13635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GVI67_RS13635	COG0131	Imidazoleglycerol-phosphate dehydratase
GVI67_RS13640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GVI67_RS13645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GVI67_RS13650	COG0107	imidazoleglycerol-phosphate synthase activity
GVI67_RS13655	COG0140	phosphoribosyl-ATP diphosphatase activity
GVI67_RS13655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GVI67_RS13680	COG1088	dTDP-glucose 4,6-dehydratase activity
GVI67_RS13685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GVI67_RS13695	COG0438	transferase activity, transferring glycosyl groups
GVI67_RS13710	COG0438	transferase activity, transferring glycosyl groups
GVI67_RS13720	COG1216	Glycosyl transferase, family 2
GVI67_RS13740	COG0438	transferase activity, transferring glycosyl groups
GVI67_RS13745	COG2327	Polysaccharide pyruvyl transferase
GVI67_RS13750	COG2244	polysaccharide biosynthetic process
GVI67_RS13755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GVI67_RS13760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GVI67_RS13770	COG0297	glycogen (starch) synthase activity
GVI67_RS13775	COG1051	belongs to the nudix hydrolase family
GVI67_RS13780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GVI67_RS13785	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GVI67_RS13790	COG0110	maltose O-acetyltransferase activity
GVI67_RS13795	COG1216	Glycosyl transferase, family 2
GVI67_RS13805	COG0438	transferase activity, transferring glycosyl groups
GVI67_RS13810	COG1045	serine acetyltransferase
GVI67_RS13815	COG0463	Glycosyl transferase, family 2
GVI67_RS13820	COG3206	protein involved in exopolysaccharide biosynthesis
GVI67_RS13820	COG0489	protein tyrosine kinase activity
GVI67_RS13835	COG1253	flavin adenine dinucleotide binding
GVI67_RS13840	COG2982	Protein involved in outer membrane biogenesis
GVI67_RS13845	COG0717	Belongs to the dCTP deaminase family
GVI67_RS13855	COG5002	protein histidine kinase activity
GVI67_RS13855	COG3447	MASE1 domain protein
GVI67_RS13855	COG5001	Diguanylate cyclase
GVI67_RS13860	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GVI67_RS13865	COG0443	Heat shock 70 kDa protein
GVI67_RS13870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS13875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS13880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS13885	COG0477	Major facilitator Superfamily
GVI67_RS13890	COG2205	protein histidine kinase activity
GVI67_RS13895	COG0745	RESPONSE REGULATOR receiver
GVI67_RS13900	COG0826	peptidase U32
GVI67_RS13905	COG1597	lipid kinase activity
GVI67_RS13910	COG1830	Aldolase
GVI67_RS13915	COG2211	Major facilitator Superfamily
GVI67_RS13920	COG1397	ADP-ribosylglycohydrolase
GVI67_RS13925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI67_RS13930	COG2188	Transcriptional regulator
GVI67_RS13935	COG0351	phosphomethylpyrimidine kinase
GVI67_RS13940	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GVI67_RS14020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GVI67_RS14025	COG0076	glutamate decarboxylase activity
GVI67_RS14030	COG0489	protein tyrosine kinase activity
GVI67_RS14030	COG3206	protein involved in exopolysaccharide biosynthesis
GVI67_RS14035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GVI67_RS14040	COG1596	polysaccharide export
GVI67_RS14045	COG5455	response to cobalt ion
GVI67_RS14055	COG0489	protein tyrosine kinase activity
GVI67_RS14065	COG4807	Protein conserved in bacteria
GVI67_RS14075	COG3275	phosphorelay sensor kinase activity
GVI67_RS14080	COG0789	Transcriptional regulator
GVI67_RS14090	COG1174	glycine betaine transport
GVI67_RS14095	COG1125	glycine betaine transport
GVI67_RS14100	COG1174	glycine betaine transport
GVI67_RS14105	COG1732	Glycine betaine
GVI67_RS14110	COG1472	Belongs to the glycosyl hydrolase 3 family
GVI67_RS14115	COG0277	FAD linked oxidase domain protein
GVI67_RS14125	COG1686	Belongs to the peptidase S11 family
GVI67_RS14135	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS14145	COG1538	Outer membrane efflux protein
GVI67_RS14150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GVI67_RS14160	COG1346	cytolysis
GVI67_RS14165	COG0295	cytidine deaminase activity
GVI67_RS14170	COG2949	membrane
GVI67_RS14180	COG1129	ABC transporter
GVI67_RS14195	COG2311	Membrane
GVI67_RS14205	COG0477	Major facilitator Superfamily
GVI67_RS14210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GVI67_RS14215	COG4771	TonB-dependent receptor
GVI67_RS14220	COG0833	amino acid
GVI67_RS14225	COG0583	DNA-binding transcription factor activity
GVI67_RS14230	COG2855	membrane
GVI67_RS14235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GVI67_RS14240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS14240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GVI67_RS14240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GVI67_RS14245	COG1105	Belongs to the carbohydrate kinase PfkB family
GVI67_RS14265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GVI67_RS14270	COG1312	Catalyzes the dehydration of D-mannonate
GVI67_RS14275	COG0246	Mannitol dehydrogenase
GVI67_RS14280	COG0523	cobalamin synthesis protein
GVI67_RS14285	COG0671	phosphoesterase, PA-phosphatase related
GVI67_RS14290	COG0791	NLP P60 protein
GVI67_RS14295	COG2200	EAL domain
GVI67_RS14300	COG4166	transmembrane transport
GVI67_RS14305	COG4174	ABC transporter (Permease)
GVI67_RS14310	COG4239	(ABC) transporter, permease
GVI67_RS14315	COG4172	Belongs to the ABC transporter superfamily
GVI67_RS14325	COG2814	Major facilitator Superfamily
GVI67_RS14330	COG1187	pseudouridine synthase activity
GVI67_RS14335	COG1061	Type III restriction enzyme res subunit
GVI67_RS14345	COG3081	Nucleoid-associated protein
GVI67_RS14350	COG3082	Protein of unknown function (DUF1414)
GVI67_RS14365	COG3182	Iron-regulated membrane protein
GVI67_RS14375	COG0579	oxidoreductase
GVI67_RS14380	COG0659	secondary active sulfate transmembrane transporter activity
GVI67_RS14385	COG2239	Acts as a magnesium transporter
GVI67_RS14390	COG4615	Cyclic peptide transporter
GVI67_RS14400	COG2169	Transcriptional regulator
GVI67_RS14400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GVI67_RS14410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GVI67_RS14415	COG2198	Histidine kinase
GVI67_RS14415	COG0642	Histidine kinase
GVI67_RS14435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GVI67_RS14450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI67_RS14455	COG0584	glycerophosphoryl diester phosphodiesterase
GVI67_RS14460	COG2271	Major facilitator Superfamily
GVI67_RS14465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GVI67_RS14470	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GVI67_RS14475	COG0247	lactate metabolic process
GVI67_RS14490	COG0642	Histidine kinase
GVI67_RS14520	COG1441	menaquinone biosynthetic process
GVI67_RS14530	COG0596	Alpha beta hydrolase
GVI67_RS14535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GVI67_RS14540	COG1169	isochorismate synthase
GVI67_RS14545	COG4575	ribosome binding
GVI67_RS14550	COG2153	protein acetylation
GVI67_RS14555	COG1234	tRNA 3'-trailer cleavage
GVI67_RS14560	COG0784	Response regulator, receiver
GVI67_RS14560	COG0835	chemotaxis
GVI67_RS14565	COG1007	ATP synthesis coupled electron transport
GVI67_RS14570	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI67_RS14575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GVI67_RS14580	COG0713	ATP synthesis coupled electron transport
GVI67_RS14585	COG0839	Belongs to the complex I subunit 6 family
GVI67_RS14595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GVI67_RS14625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI67_RS14630	COG0583	DNA-binding transcription factor activity
GVI67_RS14635	COG0436	Aminotransferase
GVI67_RS14645	COG0471	metal ion transport
GVI67_RS14645	COG0490	domain, Protein
GVI67_RS14650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI67_RS14675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GVI67_RS14680	COG3959	Transketolase, thiamine diphosphate binding domain
GVI67_RS14685	COG3037	sugar-specific permease SgaT UlaA
GVI67_RS14695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS14700	COG1609	Transcriptional regulator
GVI67_RS14710	COG0622	Phosphoesterase
GVI67_RS14715	COG0625	glutathione transferase activity
GVI67_RS14720	COG0625	glutathione transferase activity
GVI67_RS14725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GVI67_RS14730	COG1090	epimerase
GVI67_RS14735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI67_RS14740	COG4598	ABC transporter
GVI67_RS14745	COG4160	amino acid transport
GVI67_RS14755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GVI67_RS14765	COG0163	prenyltransferase activity
GVI67_RS14770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GVI67_RS14775	COG1286	toxin biosynthetic process
GVI67_RS14780	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GVI67_RS14785	COG0285	dihydrofolate synthase activity
GVI67_RS14795	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS14800	COG0101	tRNA pseudouridine synthase activity
GVI67_RS14805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GVI67_RS14810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GVI67_RS14825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI67_RS14830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GVI67_RS14830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GVI67_RS14840	COG3101	peptidyl-lysine hydroxylation
GVI67_RS14845	COG0730	response to heat
GVI67_RS14855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GVI67_RS14865	COG2840	Smr protein MutS2
GVI67_RS14870	COG2062	phosphohistidine phosphatase, SixA
GVI67_RS14875	COG1024	Enoyl-CoA hydratase
GVI67_RS14875	COG1250	3-hydroxyacyl-CoA dehydrogenase
GVI67_RS14885	COG3691	Protein conserved in bacteria
GVI67_RS14890	COG2067	long-chain fatty acid transport protein
GVI67_RS14900	COG2116	formate transmembrane transporter activity
GVI67_RS14910	COG1560	Kdo2-lipid A biosynthetic process
GVI67_RS14920	COG0436	Aminotransferase
GVI67_RS14925	COG3275	phosphorelay sensor kinase activity
GVI67_RS14930	COG3279	Response regulator of the LytR AlgR family
GVI67_RS14935	COG0837	glucose binding
GVI67_RS14945	COG3961	Belongs to the TPP enzyme family
GVI67_RS14950	COG0667	Aldo Keto reductase
GVI67_RS14960	COG1914	H( )-stimulated, divalent metal cation uptake system
GVI67_RS14965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GVI67_RS14970	COG2199	diguanylate cyclase activity
GVI67_RS14970	COG2200	EAL domain
GVI67_RS14985	COG3415	Transposase
GVI67_RS14990	COG3415	Transposase
GVI67_RS14995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GVI67_RS15025	COG0583	DNA-binding transcription factor activity
GVI67_RS15030	COG0385	Bile acid
GVI67_RS15035	COG3530	Putative quorum-sensing-regulated virulence factor
GVI67_RS15040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GVI67_RS15045	COG3115	cell septum assembly
GVI67_RS15060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS15085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GVI67_RS15090	COG4208	sulfate ABC transporter
GVI67_RS15095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GVI67_RS15100	COG4150	thiosulfate binding
GVI67_RS15105	COG2837	iron assimilation
GVI67_RS15125	COG0860	N-Acetylmuramoyl-L-alanine amidase
GVI67_RS15130	COG0408	coproporphyrinogen oxidase activity
GVI67_RS15145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GVI67_RS15150	COG5342	invasion associated locus B
GVI67_RS15155	COG0494	nUDIX hydrolase
GVI67_RS15160	COG0493	'glutamate synthase
GVI67_RS15160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI67_RS15170	COG3850	Histidine kinase
GVI67_RS15175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS15185	COG1393	Belongs to the ArsC family
GVI67_RS15190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GVI67_RS15200	COG0400	carboxylic ester hydrolase activity
GVI67_RS15210	COG2321	neutral zinc metallopeptidase
GVI67_RS15215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GVI67_RS15220	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GVI67_RS15230	COG2716	regulation of RNA biosynthetic process
GVI67_RS15235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GVI67_RS15240	COG0628	permease
GVI67_RS15245	COG4783	chaperone-mediated protein folding
GVI67_RS15250	COG1393	Belongs to the ArsC family
GVI67_RS15265	COG1446	asparaginase
GVI67_RS15270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GVI67_RS15280	COG2233	PERMEase
GVI67_RS15285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GVI67_RS15290	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS15300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GVI67_RS15315	COG2200	EAL domain
GVI67_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS15340	COG3713	MltA-interacting MipA family protein
GVI67_RS15345	COG0745	RESPONSE REGULATOR receiver
GVI67_RS15365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS15370	COG2207	Transcriptional regulator
GVI67_RS15370	COG3708	Transcriptional regulator
GVI67_RS15395	COG0464	growth
GVI67_RS15410	COG3093	addiction module antidote protein HigA
GVI67_RS15415	COG3846	protein secretion by the type IV secretion system
GVI67_RS15460	COG0582	viral genome integration into host DNA
GVI67_RS15470	COG0517	IMP dehydrogenase activity
GVI67_RS15470	COG0516	GMP reductase activity
GVI67_RS15475	COG1570	exodeoxyribonuclease VII activity
GVI67_RS15490	COG1645	bacterial-type flagellum-dependent swarming motility
GVI67_RS15520	COG1160	GTP binding
GVI67_RS15530	COG2976	Protein conserved in bacteria
GVI67_RS15535	COG0124	histidyl-tRNA synthetase
GVI67_RS15540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GVI67_RS15550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GVI67_RS15570	COG0437	4 iron, 4 sulfur cluster binding
GVI67_RS15575	COG0243	molybdopterin cofactor binding
GVI67_RS15580	COG4953	penicillin-binding protein 1C
GVI67_RS15585	COG2373	Large extracellular alpha-helical protein
GVI67_RS15590	COG1263	PTS System
GVI67_RS15590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS15590	COG2190	(PTS) system
GVI67_RS15600	COG2897	thiosulfate sulfurtransferase activity
GVI67_RS15605	COG1737	Transcriptional regulator
GVI67_RS15615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GVI67_RS15620	COG2975	iron-sulfur cluster assembly
GVI67_RS15625	COG0633	Ferredoxin
GVI67_RS15630	COG0443	Heat shock 70 kDa protein
GVI67_RS15635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GVI67_RS15640	COG0316	Belongs to the HesB IscA family
GVI67_RS15645	COG0822	iron-sulfur transferase activity
GVI67_RS15650	COG1104	cysteine desulfurase activity
GVI67_RS15670	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GVI67_RS15680	COG3711	transcriptional antiterminator
GVI67_RS15685	COG2814	Major facilitator Superfamily
GVI67_RS15690	COG2259	Doxx family
GVI67_RS15700	COG1017	nitric oxide dioxygenase activity
GVI67_RS15700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GVI67_RS15705	COG0347	Belongs to the P(II) protein family
GVI67_RS15710	COG2204	response regulator
GVI67_RS15715	COG3170	Tfp pilus assembly protein FimV
GVI67_RS15720	COG2205	protein histidine kinase activity
GVI67_RS15725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GVI67_RS15725	COG0047	phosphoribosylformylglycinamidine synthase activity
GVI67_RS15730	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GVI67_RS15740	COG0560	Phosphoserine phosphatase
GVI67_RS15745	COG1263	PTS System
GVI67_RS15745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS15750	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GVI67_RS15755	COG1737	Transcriptional regulator
GVI67_RS15760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI67_RS15770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GVI67_RS15775	COG1381	Involved in DNA repair and RecF pathway recombination
GVI67_RS15780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GVI67_RS15790	COG0681	Belongs to the peptidase S26 family
GVI67_RS15800	COG3086	response to oxidative stress
GVI67_RS15810	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GVI67_RS15820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GVI67_RS15825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GVI67_RS15830	COG0513	Belongs to the DEAD box helicase family
GVI67_RS15835	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GVI67_RS15840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GVI67_RS15845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GVI67_RS15850	COG3118	belongs to the thioredoxin family
GVI67_RS15855	COG3148	PFAM DTW domain containing protein
GVI67_RS15860	COG1042	CoA-binding domain protein
GVI67_RS15860	COG0045	succinate-CoA ligase (ADP-forming) activity
GVI67_RS15860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GVI67_RS15865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GVI67_RS15870	COG5544	Lipoprotein
GVI67_RS15875	COG0477	Major facilitator Superfamily
GVI67_RS15905	COG0542	response to heat
GVI67_RS15915	COG0564	pseudouridine synthase activity
GVI67_RS15920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GVI67_RS15925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GVI67_RS15935	COG1605	Chorismate mutase
GVI67_RS15935	COG0077	Prephenate dehydratase
GVI67_RS15945	COG0287	Prephenate dehydrogenase
GVI67_RS15945	COG1605	Chorismate mutase
GVI67_RS15950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GVI67_RS15965	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS15975	COG2885	chlorophyll binding
GVI67_RS15995	COG0336	Belongs to the RNA methyltransferase TrmD family
GVI67_RS16000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GVI67_RS16010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GVI67_RS16015	COG4137	Cytochrome C assembly protein
GVI67_RS16020	COG4536	flavin adenine dinucleotide binding
GVI67_RS16025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GVI67_RS16030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GVI67_RS16035	COG0497	DNA recombination
GVI67_RS16050	COG2867	negative regulation of translational initiation
GVI67_RS16065	COG0582	viral genome integration into host DNA
GVI67_RS16125	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GVI67_RS16130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GVI67_RS16140	COG1263	PTS System
GVI67_RS16140	COG2190	(PTS) system
GVI67_RS16140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS16150	COG1401	restriction endodeoxyribonuclease activity
GVI67_RS16150	COG1401	restriction endodeoxyribonuclease activity
GVI67_RS16160	COG2826	transposase and inactivated derivatives, IS30 family
GVI67_RS16175	COG3813	Protein conserved in bacteria
GVI67_RS16195	COG0401	homolog of Blt101
GVI67_RS16200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI67_RS16225	COG4575	ribosome binding
GVI67_RS16235	COG1780	Probably involved in ribonucleotide reductase function
GVI67_RS16250	COG4175	Glycine betaine
GVI67_RS16255	COG4176	ABC-type proline glycine betaine transport system permease component
GVI67_RS16265	COG2814	Major facilitator Superfamily
GVI67_RS16270	COG1846	Transcriptional regulator
GVI67_RS16275	COG1566	PFAM secretion protein HlyD family protein
GVI67_RS16280	COG2814	Major facilitator Superfamily
GVI67_RS16285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GVI67_RS16300	COG2918	glutathione biosynthetic process
GVI67_RS16305	COG1238	metal cluster binding
GVI67_RS16310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI67_RS16340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GVI67_RS16345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GVI67_RS16360	COG1546	Belongs to the CinA family
GVI67_RS16370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GVI67_RS16380	COG2951	lytic endotransglycosylase activity
GVI67_RS16385	COG0517	IMP dehydrogenase activity
GVI67_RS16385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GVI67_RS16390	COG3604	Transcriptional regulator
GVI67_RS16395	COG0426	domain, Protein
GVI67_RS16395	COG1773	rubredoxin
GVI67_RS16400	COG0446	pyridine nucleotide-disulphide oxidoreductase
GVI67_RS16405	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GVI67_RS16410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GVI67_RS16415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI67_RS16420	COG1609	Transcriptional regulator
GVI67_RS16425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS16425	COG1263	PTS System
GVI67_RS16430	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS16435	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GVI67_RS16445	COG3260	NADH ubiquinone oxidoreductase 20
GVI67_RS16450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GVI67_RS16455	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GVI67_RS16455	COG3261	NADH dehydrogenase
GVI67_RS16460	COG0650	Formate hydrogenlyase subunit 4
GVI67_RS16465	COG0651	ATP synthesis coupled electron transport
GVI67_RS16470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI67_RS16480	COG0375	protein maturation
GVI67_RS16485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GVI67_RS16490	COG0298	carbon dioxide binding
GVI67_RS16495	COG0409	Hydrogenase expression formation protein
GVI67_RS16500	COG0309	Hydrogenase expression formation protein (HypE)
GVI67_RS16515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GVI67_RS16520	COG1120	ATPase activity
GVI67_RS16540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GVI67_RS16550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GVI67_RS16555	COG0163	prenyltransferase activity
GVI67_RS16570	COG0477	Major facilitator Superfamily
GVI67_RS16585	COG4942	peptidase
GVI67_RS16585	COG1388	LysM domain
GVI67_RS16600	COG0585	pseudouridine synthase activity
GVI67_RS16610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GVI67_RS16615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GVI67_RS16625	COG0529	Catalyzes the synthesis of activated sulfate
GVI67_RS16645	COG2234	aminopeptidase activity
GVI67_RS16660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GVI67_RS16665	COG0720	synthase
GVI67_RS16675	COG1473	amidohydrolase
GVI67_RS16685	COG0602	queuosine metabolic process
GVI67_RS16690	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GVI67_RS16695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GVI67_RS16695	COG1263	PTS System
GVI67_RS16695	COG2190	(PTS) system
GVI67_RS16700	COG1737	Transcriptional regulator
GVI67_RS16715	COG3956	TIGRFAM MazG family protein
GVI67_RS16720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GVI67_RS16725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GVI67_RS16730	COG2205	protein histidine kinase activity
GVI67_RS16730	COG4999	Histidine kinase
GVI67_RS16730	COG3850	Histidine kinase
GVI67_RS16730	COG3437	response regulator, receiver
GVI67_RS16735	COG1929	Belongs to the glycerate kinase type-1 family
GVI67_RS16740	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS16745	COG4948	Mandelate Racemase Muconate Lactonizing
GVI67_RS16750	COG2271	Major facilitator Superfamily
GVI67_RS16755	COG0716	FMN binding
GVI67_RS16760	COG0564	pseudouridine synthase activity
GVI67_RS16765	COG3098	single-species biofilm formation
GVI67_RS16780	COG1611	Belongs to the LOG family
GVI67_RS16785	COG0814	amino acid
GVI67_RS16790	COG1760	l-serine dehydratase
GVI67_RS16800	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GVI67_RS16805	COG2363	Small membrane protein
GVI67_RS16810	COG0583	DNA-binding transcription factor activity
GVI67_RS16820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GVI67_RS16825	COG2166	iron-sulfur cluster assembly
GVI67_RS16830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GVI67_RS16835	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GVI67_RS16855	COG0860	N-Acetylmuramoyl-L-alanine amidase
GVI67_RS16860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GVI67_RS16860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GVI67_RS16865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GVI67_RS16870	COG1074	ATP-dependent DNA helicase activity
GVI67_RS16880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GVI67_RS16885	COG4967	type IV pilus modification protein PilV
GVI67_RS16895	COG4795	General secretion pathway protein
GVI67_RS16900	COG2165	general secretion pathway protein
GVI67_RS16905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GVI67_RS16910	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GVI67_RS16920	COG0494	nUDIX hydrolase
GVI67_RS16925	COG3066	DNA modification
GVI67_RS16935	COG0667	Aldo Keto reductase
GVI67_RS16940	COG0477	Major facilitator Superfamily
GVI67_RS16945	COG0204	Acyl-transferase
GVI67_RS16945	COG0318	PFAM AMP-dependent synthetase and ligase
GVI67_RS16950	COG1609	Transcriptional regulator
GVI67_RS16960	COG2186	Transcriptional regulator
GVI67_RS16965	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS16970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GVI67_RS16975	COG1609	Transcriptional regulator
GVI67_RS16985	COG0583	DNA-binding transcription factor activity
GVI67_RS16990	COG1794	racemase activity, acting on amino acids and derivatives
GVI67_RS17000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GVI67_RS17005	COG1175	transmembrane transport
GVI67_RS17010	COG0395	ABC-type sugar transport system, permease component
GVI67_RS17015	COG3842	ATPase activity
GVI67_RS17025	COG2814	Major facilitator Superfamily
GVI67_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS17035	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GVI67_RS17040	COG0823	Involved in the tonB-independent uptake of proteins
GVI67_RS17045	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI67_RS17050	COG0183	Belongs to the thiolase family
GVI67_RS17065	COG0814	amino acid
GVI67_RS17070	COG2388	GCN5-related N-acetyl-transferase
GVI67_RS17075	COG3592	Divergent 4Fe-4S mono-cluster
GVI67_RS17080	COG3729	General stress protein
GVI67_RS17085	COG3685	Protein conserved in bacteria
GVI67_RS17090	COG3685	Protein conserved in bacteria
GVI67_RS17095	COG3546	catalase activity
GVI67_RS17100	COG1271	oxidase subunit
GVI67_RS17105	COG1294	oxidase, subunit
GVI67_RS17120	COG1546	Belongs to the CinA family
GVI67_RS17135	COG3111	PFAM Bacterial OB fold (BOF) protein
GVI67_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS17145	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GVI67_RS17165	COG2067	long-chain fatty acid transport protein
GVI67_RS17245	COG0582	viral genome integration into host DNA
GVI67_RS17255	COG4942	peptidase
GVI67_RS17260	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GVI67_RS17265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GVI67_RS17275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GVI67_RS17285	COG4974	Belongs to the 'phage' integrase family
GVI67_RS17300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GVI67_RS17305	COG0354	folic acid binding
GVI67_RS17310	COG1272	protein, Hemolysin III
GVI67_RS17315	COG1737	Transcriptional regulator
GVI67_RS17320	COG2723	6-phospho-beta-galactosidase activity
GVI67_RS17340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GVI67_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS17350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GVI67_RS17350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GVI67_RS17360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GVI67_RS17365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI67_RS17370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GVI67_RS17375	COG0006	proline dipeptidase activity
GVI67_RS17385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GVI67_RS17395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GVI67_RS17400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GVI67_RS17405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GVI67_RS17410	COG0583	DNA-binding transcription factor activity
GVI67_RS17415	COG2968	Membrane
GVI67_RS17420	COG1279	arginine transmembrane transporter activity
GVI67_RS17425	COG0668	transmembrane transport
GVI67_RS17430	COG0191	fructose-bisphosphate aldolase activity
GVI67_RS17435	COG0126	phosphoglycerate kinase activity
GVI67_RS17440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GVI67_RS17445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GVI67_RS17450	COG0501	Belongs to the peptidase M48B family
GVI67_RS17465	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GVI67_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS17475	COG2267	carboxylic ester hydrolase activity
GVI67_RS17500	COG1414	Transcriptional regulator
GVI67_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS17520	COG2146	nitrite reductase [NAD(P)H] activity
GVI67_RS17525	COG0010	Belongs to the arginase family
GVI67_RS17530	COG1166	arginine decarboxylase activity
GVI67_RS17595	COG2814	Major facilitator Superfamily
GVI67_RS17600	COG3091	SprT-like family
GVI67_RS17605	COG2356	endonuclease I
GVI67_RS17610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GVI67_RS17630	COG2805	Type II/IV secretion system protein
GVI67_RS17635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GVI67_RS17640	COG0762	integral membrane protein
GVI67_RS17645	COG1872	DUF167
GVI67_RS17655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GVI67_RS17660	COG2852	Protein conserved in bacteria
GVI67_RS17670	COG3171	Protein conserved in bacteria
GVI67_RS17680	COG1194	a g-specific adenine glycosylase
GVI67_RS17690	COG0741	lytic transglycosylase activity
GVI67_RS17695	COG2211	Major facilitator Superfamily
GVI67_RS17700	COG1982	Orn Lys Arg decarboxylase major
GVI67_RS17705	COG1811	Na channel or pump
GVI67_RS17730	COG0726	polysaccharide deacetylase
GVI67_RS17730	COG1649	PFAM Uncharacterised BCR, COG1649
GVI67_RS17735	COG1215	transferase activity, transferring glycosyl groups
GVI67_RS17745	COG0754	glutathionylspermidine amidase activity
GVI67_RS17750	COG0625	glutathione transferase activity
GVI67_RS17760	COG1349	DNA-binding transcription factor activity
GVI67_RS17765	COG0840	transmembrane signaling receptor activity
GVI67_RS17770	COG0667	Aldo Keto reductase
GVI67_RS17775	COG2862	Uncharacterized protein family, UPF0114
GVI67_RS17795	COG0848	biopolymer transport protein
GVI67_RS17805	COG0626	cystathionine gamma-synthase activity
GVI67_RS17810	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS17815	COG2207	Transcriptional regulator
GVI67_RS17820	COG1979	alcohol dehydrogenase
GVI67_RS17850	COG0640	Transcriptional regulator
GVI67_RS17855	COG0431	NADPH-dependent FMN reductase
GVI67_RS17890	COG1609	Transcriptional regulator
GVI67_RS17900	COG2223	nitrite transmembrane transporter activity
GVI67_RS17920	COG2801	Transposase and inactivated derivatives
GVI67_RS17965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GVI67_RS17985	COG3111	PFAM Bacterial OB fold (BOF) protein
GVI67_RS18000	COG2249	NAD(P)H dehydrogenase (quinone) activity
GVI67_RS18005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GVI67_RS18010	COG1652	LysM domain
GVI67_RS18015	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GVI67_RS18020	COG2211	Major facilitator Superfamily
GVI67_RS18035	COG0187	DNA topoisomerase II activity
GVI67_RS18040	COG3150	esterase
GVI67_RS18045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GVI67_RS18050	COG3151	Protein conserved in bacteria
GVI67_RS18055	COG0494	nUDIX hydrolase
GVI67_RS18070	COG0754	glutathionylspermidine amidase activity
GVI67_RS18075	COG3384	dioxygenase
GVI67_RS18085	COG3539	Fimbrial protein
GVI67_RS18090	COG3188	usher protein
GVI67_RS18095	COG3121	Chaperone
GVI67_RS18100	COG3539	Fimbrial protein
GVI67_RS18105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GVI67_RS18115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GVI67_RS18115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GVI67_RS18125	COG3025	triphosphatase activity
GVI67_RS18130	COG4991	sh3 domain protein
GVI67_RS18135	COG0617	tRNA 3'-terminal CCA addition
GVI67_RS18145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GVI67_RS18155	COG0829	nickel cation binding
GVI67_RS18160	COG0831	urea catabolic process
GVI67_RS18165	COG0832	Belongs to the urease beta subunit family
GVI67_RS18170	COG0804	urea catabolic process
GVI67_RS18175	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GVI67_RS18185	COG0830	nickel cation binding
GVI67_RS18190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GVI67_RS18200	COG2197	response regulator
GVI67_RS18210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GVI67_RS18215	COG0358	DNA primase activity
GVI67_RS18225	COG3663	DNA glycosylase
GVI67_RS18275	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GVI67_RS18280	COG5301	cellulose 1,4-beta-cellobiosidase activity
GVI67_RS18280	COG5301	cellulose 1,4-beta-cellobiosidase activity
GVI67_RS18365	COG4695	Portal protein
GVI67_RS18395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GVI67_RS18430	COG4974	Belongs to the 'phage' integrase family
GVI67_RS18455	COG4626	Terminase
GVI67_RS18455	COG1802	Transcriptional regulator
GVI67_RS18525	COG3561	AntA/AntB antirepressor
GVI67_RS18540	COG0582	viral genome integration into host DNA
GVI67_RS18565	COG3210	domain, Protein
GVI67_RS18570	COG3210	domain, Protein
GVI67_RS18585	COG3210	domain, Protein
GVI67_RS18600	COG2375	cellular response to nickel ion
GVI67_RS18605	COG1695	Transcriptional regulator
GVI67_RS18610	COG0840	transmembrane signaling receptor activity
GVI67_RS18615	COG0840	transmembrane signaling receptor activity
GVI67_RS18620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GVI67_RS18635	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GVI67_RS18640	COG1830	Aldolase
GVI67_RS18645	COG1879	ABC-type sugar transport system periplasmic component
GVI67_RS18650	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS18655	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS18660	COG1129	ABC transporter
GVI67_RS18665	COG2390	Transcriptional regulator
GVI67_RS18670	COG1070	Carbohydrate kinase
GVI67_RS18675	COG0446	pyridine nucleotide-disulphide oxidoreductase
GVI67_RS18675	COG1902	pentaerythritol trinitrate reductase activity
GVI67_RS18685	COG1451	nucleotide metabolic process
GVI67_RS18690	COG0673	inositol 2-dehydrogenase activity
GVI67_RS18695	COG0861	Integral membrane protein TerC family
GVI67_RS18705	COG2721	sulfolactate sulfo-lyase activity
GVI67_RS18715	COG2271	Major facilitator Superfamily
GVI67_RS18720	COG2186	Transcriptional regulator
GVI67_RS18725	COG0586	Pfam SNARE associated Golgi protein
GVI67_RS18735	COG1422	Protein of unknown function (DUF1090)
GVI67_RS18740	COG4575	ribosome binding
GVI67_RS18745	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GVI67_RS18755	COG2259	Doxx family
GVI67_RS18760	COG0435	Glutathione S-transferase
GVI67_RS18765	COG3152	Membrane
GVI67_RS18770	COG0583	DNA-binding transcription factor activity
GVI67_RS18775	COG1741	Belongs to the pirin family
GVI67_RS18785	COG0814	amino acid
GVI67_RS18790	COG1882	Formate acetyltransferase
GVI67_RS18795	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GVI67_RS18800	COG0814	amino acid
GVI67_RS18805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GVI67_RS18810	COG0583	DNA-binding transcription factor activity
GVI67_RS18820	COG1929	Belongs to the glycerate kinase type-1 family
GVI67_RS18825	COG2084	Dehydrogenase
GVI67_RS18835	COG2721	sulfolactate sulfo-lyase activity
GVI67_RS18850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS18855	COG3414	Phosphotransferase system galactitol-specific IIB component
GVI67_RS18860	COG3775	system Galactitol-specific IIC component
GVI67_RS18865	COG1063	alcohol dehydrogenase
GVI67_RS18880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GVI67_RS18885	COG3107	peptidoglycan biosynthetic process
GVI67_RS18890	COG0792	nuclease activity
GVI67_RS18895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GVI67_RS18900	COG2823	Periplasmic or secreted lipoprotein
GVI67_RS18905	COG0701	Predicted permease
GVI67_RS18910	COG0702	epimerase
GVI67_RS18915	COG0693	protein deglycase activity
GVI67_RS18920	COG3787	Belongs to the UPF0306 family
GVI67_RS18925	COG2827	Endonuclease containing a URI domain
GVI67_RS18930	COG3153	acetyltransferase
GVI67_RS18935	COG3154	lipid carrier protein
GVI67_RS18940	COG0826	peptidase U32
GVI67_RS18945	COG0826	peptidase U32
GVI67_RS18950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GVI67_RS18955	COG2801	Transposase and inactivated derivatives
GVI67_RS18955	COG3415	Transposase
GVI67_RS18960	COG0814	amino acid
GVI67_RS18965	COG0513	Belongs to the DEAD box helicase family
GVI67_RS18985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GVI67_RS18990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GVI67_RS18995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GVI67_RS19000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GVI67_RS19020	COG0137	argininosuccinate synthase activity
GVI67_RS19030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GVI67_RS19035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GVI67_RS19040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GVI67_RS19050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GVI67_RS19055	COG1534	Rna-binding protein
GVI67_RS19065	COG2027	D-alanyl-D-alanine carboxypeptidase
GVI67_RS19070	COG0745	RESPONSE REGULATOR receiver
GVI67_RS19075	COG0642	Histidine kinase
GVI67_RS19080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GVI67_RS19085	COG0697	spore germination
GVI67_RS19095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GVI67_RS19100	COG0142	geranyltranstransferase activity
GVI67_RS19105	COG3423	Transcriptional regulator
GVI67_RS19110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GVI67_RS19115	COG5007	Belongs to the BolA IbaG family
GVI67_RS19120	COG3113	response to antibiotic
GVI67_RS19125	COG2854	intermembrane phospholipid transfer
GVI67_RS19130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GVI67_RS19135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GVI67_RS19140	COG1127	ABC transporter
GVI67_RS19145	COG0530	calcium, potassium:sodium antiporter activity
GVI67_RS19155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GVI67_RS19160	COG3117	lipopolysaccharide transmembrane transporter activity
GVI67_RS19165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GVI67_RS19170	COG1137	ATPase activity
GVI67_RS19175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GVI67_RS19195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS19205	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GVI67_RS19210	COG2198	Histidine kinase
GVI67_RS19210	COG0784	Response regulator, receiver
GVI67_RS19210	COG5002	protein histidine kinase activity
GVI67_RS19215	COG0795	lipopolysaccharide-transporting ATPase activity
GVI67_RS19220	COG0795	lipopolysaccharide-transporting ATPase activity
GVI67_RS19225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GVI67_RS19230	COG2927	DNA polymerase III (CHI subunit)
GVI67_RS19240	COG0456	acetyltransferase
GVI67_RS19245	COG1064	alcohol dehydrogenase
GVI67_RS19255	COG0433	COG0433 Predicted ATPase
GVI67_RS19260	COG1242	4 iron, 4 sulfur cluster binding
GVI67_RS19265	COG0070	glutamate synthase
GVI67_RS19265	COG0069	glutamate synthase activity
GVI67_RS19265	COG0067	glutamate synthase
GVI67_RS19270	COG0493	'glutamate synthase
GVI67_RS19280	COG3188	usher protein
GVI67_RS19285	COG3121	Chaperone
GVI67_RS19290	COG2969	positive regulation of protein catabolic process
GVI67_RS19295	COG0625	glutathione transferase activity
GVI67_RS19300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GVI67_RS19310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GVI67_RS19315	COG3105	Protein conserved in bacteria
GVI67_RS19320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI67_RS19325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GVI67_RS19335	COG1438	arginine binding
GVI67_RS19345	COG2732	(Barnase) inhibitor
GVI67_RS19350	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS19355	COG1289	transmembrane transporter activity
GVI67_RS19370	COG0583	DNA-binding transcription factor activity
GVI67_RS19375	COG0312	modulator of DNA gyrase
GVI67_RS19380	COG3164	Protein of unknown function
GVI67_RS19395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GVI67_RS19400	COG1792	Involved in formation and maintenance of cell shape
GVI67_RS19405	COG1077	Cell shape determining protein MreB Mrl
GVI67_RS19410	COG2200	EAL domain
GVI67_RS19410	COG2199	diguanylate cyclase activity
GVI67_RS19415	COG0604	alcohol dehydrogenase
GVI67_RS19425	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GVI67_RS19430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GVI67_RS19435	COG0511	ligase activity, forming carbon-carbon bonds
GVI67_RS19440	COG0439	Biotin carboxylase
GVI67_RS19445	COG3924	membrane
GVI67_RS19450	COG4145	pantothenate transmembrane transporter activity
GVI67_RS19485	COG1309	transcriptional regulator
GVI67_RS19490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS19495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GVI67_RS19535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GVI67_RS19550	COG0009	L-threonylcarbamoyladenylate synthase
GVI67_RS19555	COG0551	DNA topoisomerase type I activity
GVI67_RS19560	COG2922	Belongs to the Smg family
GVI67_RS19565	COG0758	DNA mediated transformation
GVI67_RS19570	COG0242	peptide deformylase activity
GVI67_RS19575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GVI67_RS19580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GVI67_RS19580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GVI67_RS19590	COG1970	mechanosensitive ion channel activity
GVI67_RS19595	COG3036	rescue of stalled ribosome
GVI67_RS19600	COG0789	Transcriptional regulator
GVI67_RS19615	COG0202	RNA polymerase activity
GVI67_RS19625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GVI67_RS19640	COG0201	protein transport
GVI67_RS19650	COG1841	ribosomal large subunit assembly
GVI67_RS19665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GVI67_RS19670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GVI67_RS19700	COG0255	Belongs to the universal ribosomal protein uL29 family
GVI67_RS19705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GVI67_RS19745	COG0051	transcription antitermination factor activity, RNA binding
GVI67_RS19785	COG2168	tRNA wobble position uridine thiolation
GVI67_RS19790	COG2923	Belongs to the DsrF TusC family
GVI67_RS19795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GVI67_RS19800	COG2964	Protein conserved in bacteria
GVI67_RS19805	COG0545	Peptidyl-prolyl cis-trans isomerase
GVI67_RS19815	COG1047	Peptidyl-prolyl cis-trans
GVI67_RS19820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GVI67_RS19825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GVI67_RS19825	COG0475	glutathione-regulated potassium exporter activity
GVI67_RS19830	COG2249	NAD(P)H dehydrogenase (quinone) activity
GVI67_RS19835	COG0488	(ABC) transporter
GVI67_RS19845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GVI67_RS19855	COG0679	Auxin Efflux Carrier
GVI67_RS19885	COG0429	hydrolase of the alpha beta-hydrolase fold
GVI67_RS19890	COG3089	Belongs to the UPF0270 family
GVI67_RS19895	COG3954	Phosphoribulokinase
GVI67_RS19900	COG1765	OsmC-like protein
GVI67_RS19910	COG1289	transmembrane transporter activity
GVI67_RS19915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GVI67_RS19925	COG2184	nucleotidyltransferase activity
GVI67_RS19935	COG0738	Major facilitator superfamily
GVI67_RS19940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GVI67_RS19950	COG1648	precorrin-2 dehydrogenase activity
GVI67_RS19950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GVI67_RS19960	COG0180	Tryptophanyl-tRNA synthetase
GVI67_RS19970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GVI67_RS19975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GVI67_RS19980	COG3266	domain, Protein
GVI67_RS19985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GVI67_RS19990	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GVI67_RS19995	COG4796	Type ii and iii secretion system protein
GVI67_RS20015	COG4972	Pilus assembly protein
GVI67_RS20020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GVI67_RS20025	COG0494	nUDIX hydrolase
GVI67_RS20035	COG1011	Hydrolase
GVI67_RS20040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GVI67_RS20045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GVI67_RS20050	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GVI67_RS20065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GVI67_RS20070	COG2183	response to ionizing radiation
GVI67_RS20075	COG1918	ferrous iron import across plasma membrane
GVI67_RS20095	COG1040	competence protein
GVI67_RS20105	COG2610	gluconate transmembrane transporter activity
GVI67_RS20110	COG1640	4-alpha-glucanotransferase
GVI67_RS20115	COG0058	SHG alpha-glucan phosphorylase activity
GVI67_RS20120	COG2909	trisaccharide binding
GVI67_RS20125	COG1349	DNA-binding transcription factor activity
GVI67_RS20130	COG0705	Rhomboid family
GVI67_RS20135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GVI67_RS20140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GVI67_RS20145	COG0058	SHG alpha-glucan phosphorylase activity
GVI67_RS20150	COG0297	glycogen (starch) synthase activity
GVI67_RS20155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GVI67_RS20160	COG1523	belongs to the glycosyl hydrolase 13 family
GVI67_RS20165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GVI67_RS20170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GVI67_RS20175	COG2095	MarC family integral membrane protein
GVI67_RS20180	COG2610	gluconate transmembrane transporter activity
GVI67_RS20185	COG3265	gluconokinase activity
GVI67_RS20190	COG1609	Transcriptional regulator
GVI67_RS20195	COG1741	Belongs to the pirin family
GVI67_RS20200	COG0673	inositol 2-dehydrogenase activity
GVI67_RS20205	COG1247	-acetyltransferase
GVI67_RS20210	COG0405	Gamma-glutamyltransferase
GVI67_RS20220	COG0584	glycerophosphoryl diester phosphodiesterase
GVI67_RS20250	COG0411	ABC transporter
GVI67_RS20265	COG0683	leucine binding
GVI67_RS20270	COG0456	acetyltransferase
GVI67_RS20275	COG0683	leucine binding
GVI67_RS20280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GVI67_RS20285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GVI67_RS20290	COG2177	Part of the ABC transporter FtsEX involved in
GVI67_RS20295	COG2884	Cell division ATP-binding protein ftsE
GVI67_RS20300	COG0552	protein localization to endoplasmic reticulum
GVI67_RS20305	COG0742	ribosomal rna small subunit methyltransferase
GVI67_RS20310	COG3776	membrane
GVI67_RS20320	COG3714	YhhN family
GVI67_RS20340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GVI67_RS20345	COG0425	Belongs to the sulfur carrier protein TusA family
GVI67_RS20350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GVI67_RS20360	COG0628	permease
GVI67_RS20380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GVI67_RS20400	COG1216	Glycosyl transferase, family 2
GVI67_RS20425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI67_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS20440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GVI67_RS20450	COG3479	Phenolic acid decarboxylase
GVI67_RS20455	COG0583	DNA-binding transcription factor activity
GVI67_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS20480	COG1414	Transcriptional regulator
GVI67_RS20485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GVI67_RS20490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GVI67_RS20500	COG2205	protein histidine kinase activity
GVI67_RS20505	COG0745	RESPONSE REGULATOR receiver
GVI67_RS20510	COG1276	copper resistance
GVI67_RS20515	COG2372	response to copper ion
GVI67_RS20520	COG3667	copper resistance
GVI67_RS20525	COG2132	Multicopper oxidase
GVI67_RS20535	COG0739	heme binding
GVI67_RS20565	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GVI67_RS20610	COG2081	HI0933 family
GVI67_RS20615	COG0306	phosphate transporter
GVI67_RS20625	COG0589	response to stress
GVI67_RS20635	COG0339	signal peptide processing
GVI67_RS20640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GVI67_RS20645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GVI67_RS20675	COG2197	response regulator
GVI67_RS20680	COG1028	Short-chain dehydrogenase reductase Sdr
GVI67_RS20685	COG0583	DNA-binding transcription factor activity
GVI67_RS20690	COG1295	ribonuclease BN
GVI67_RS20695	COG0477	Major facilitator Superfamily
GVI67_RS20700	COG2982	Protein involved in outer membrane biogenesis
GVI67_RS20705	COG2200	EAL domain
GVI67_RS20715	COG0612	Peptidase, M16
GVI67_RS20720	COG1301	dicarboxylic acid transport
GVI67_RS20725	COG2200	EAL domain
GVI67_RS20725	COG2199	diguanylate cyclase activity
GVI67_RS20730	COG0457	Tetratricopeptide repeat
GVI67_RS20730	COG3118	belongs to the thioredoxin family
GVI67_RS20735	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GVI67_RS20740	COG1215	transferase activity, transferring glycosyl groups
GVI67_RS20770	COG2194	sulfuric ester hydrolase activity
GVI67_RS20780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GVI67_RS20810	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GVI67_RS20820	COG1739	Uncharacterized protein family UPF0029
GVI67_RS20825	COG0006	proline dipeptidase activity
GVI67_RS20830	COG1250	3-hydroxyacyl-CoA dehydrogenase
GVI67_RS20830	COG1024	Enoyl-CoA hydratase
GVI67_RS20835	COG0183	Belongs to the thiolase family
GVI67_RS20840	COG0751	glycine-tRNA ligase activity
GVI67_RS20845	COG0752	glycyl-tRNA synthetase alpha subunit
GVI67_RS20855	COG3274	enterobacterial common antigen metabolic process
GVI67_RS20860	COG1070	Carbohydrate kinase
GVI67_RS20865	COG2115	Belongs to the xylose isomerase family
GVI67_RS20870	COG4213	ABC transporter substrate-binding protein
GVI67_RS20880	COG4214	carbohydrate transport
GVI67_RS20885	COG1609	Transcriptional regulator
GVI67_RS20885	COG2207	Transcriptional regulator
GVI67_RS20890	COG2992	FlgJ-related protein
GVI67_RS20895	COG0366	Alpha amylase catalytic
GVI67_RS20900	COG3977	Valine--pyruvate aminotransferase
GVI67_RS20905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GVI67_RS20915	COG2211	Major facilitator Superfamily
GVI67_RS20925	COG1012	belongs to the aldehyde dehydrogenase family
GVI67_RS20930	COG1940	carbohydrate kinase activity
GVI67_RS20935	COG3276	selenocysteine insertion sequence binding
GVI67_RS20945	COG0625	glutathione transferase activity
GVI67_RS20950	COG1566	PFAM secretion protein HlyD family protein
GVI67_RS20965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GVI67_RS20965	COG2213	PTS system mannitol-specific
GVI67_RS20975	COG3722	fumarate hydratase activity
GVI67_RS21000	COG3121	Chaperone
GVI67_RS21015	COG2186	Transcriptional regulator
GVI67_RS21025	COG2271	Major facilitator Superfamily
GVI67_RS21030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GVI67_RS21040	COG0583	DNA-binding transcription factor activity
GVI67_RS21045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GVI67_RS21055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GVI67_RS21060	COG3978	acetolactate synthase activity
GVI67_RS21085	COG3085	chromosome segregation
GVI67_RS21135	COG4206	TonB-dependent receptor
GVI67_RS21140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GVI67_RS21160	COG0583	DNA-binding transcription factor activity
GVI67_RS21165	COG0165	Argininosuccinate lyase
GVI67_RS21180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GVI67_RS21185	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GVI67_RS21190	COG0371	Dehydrogenase
GVI67_RS21195	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GVI67_RS21205	COG0460	homoserine dehydrogenase
GVI67_RS21205	COG0527	aspartate kinase activity
GVI67_RS21210	COG0626	cystathionine gamma-synthase activity
GVI67_RS21225	COG0254	rRNA binding
GVI67_RS21230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GVI67_RS21235	COG1609	Transcriptional regulator
GVI67_RS21240	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GVI67_RS21255	COG1575	Belongs to the MenA family. Type 1 subfamily
GVI67_RS21260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GVI67_RS21265	COG3074	FtsZ-dependent cytokinesis
GVI67_RS21270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GVI67_RS21280	COG1494	fructose-1,6-bisphosphatase
GVI67_RS21290	COG3152	Membrane
GVI67_RS21300	COG0149	triose-phosphate isomerase activity
GVI67_RS21310	COG2134	cdp-diacylglycerol pyrophosphatase
GVI67_RS21320	COG0205	6-phosphofructokinase activity
GVI67_RS21340	COG0464	growth
GVI67_RS21360	COG3678	ATP-independent chaperone mediated protein folding
GVI67_RS21365	COG0745	RESPONSE REGULATOR receiver
GVI67_RS21370	COG2205	protein histidine kinase activity
GVI67_RS21375	COG2258	MOSC domain
GVI67_RS21390	COG4977	sequence-specific DNA binding
GVI67_RS21390	COG1917	Cupin 2, conserved barrel domain protein
GVI67_RS21395	COG4977	sequence-specific DNA binding
GVI67_RS21400	COG1070	Carbohydrate kinase
GVI67_RS21405	COG4806	L-rhamnose isomerase
GVI67_RS21420	COG1129	ABC transporter
GVI67_RS21425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS21435	COG1454	alcohol dehydrogenase
GVI67_RS21450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GVI67_RS21465	COG3188	usher protein
GVI67_RS21470	COG3121	Chaperone
GVI67_RS21495	COG0437	4 iron, 4 sulfur cluster binding
GVI67_RS21500	COG2864	formate dehydrogenase
GVI67_RS21505	COG3058	Necessary for formate dehydrogenase activity
GVI67_RS21520	COG0456	acetyltransferase
GVI67_RS21535	COG1011	Hydrolase
GVI67_RS21540	COG1349	DNA-binding transcription factor activity
GVI67_RS21545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI67_RS21555	COG3684	Belongs to the aldolase LacD family
GVI67_RS21565	COG1501	Belongs to the glycosyl hydrolase 31 family
GVI67_RS21580	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GVI67_RS21595	COG3852	Histidine kinase
GVI67_RS21610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GVI67_RS21615	COG3078	GTPase activator activity
GVI67_RS21630	COG0204	Acyl-transferase
GVI67_RS21640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GVI67_RS21645	COG3084	Protein conserved in bacteria
GVI67_RS21650	COG0746	molybdenum cofactor guanylyltransferase activity
GVI67_RS21655	COG1763	Mo-molybdopterin cofactor biosynthetic process
GVI67_RS21680	COG2186	Transcriptional regulator
GVI67_RS21685	COG0477	Major facilitator Superfamily
GVI67_RS21690	COG1609	Transcriptional regulator
GVI67_RS21695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GVI67_RS21705	COG1172	Belongs to the binding-protein-dependent transport system permease family
GVI67_RS21710	COG1129	ABC transporter
GVI67_RS21715	COG1869	D-ribose catabolic process
GVI67_RS21720	COG3158	transport of potassium into the cell
GVI67_RS21730	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GVI67_RS21735	COG2502	aspartate--ammonia ligase
GVI67_RS21740	COG1522	sequence-specific DNA binding
GVI67_RS21745	COG0716	FMN binding
GVI67_RS21750	COG0445	tRNA wobble uridine modification
GVI67_RS21755	COG0357	Ribosomal RNA small subunit methyltransferase G
GVI67_RS21760	COG3312	ion transport
GVI67_RS21765	COG0356	it plays a direct role in the translocation of protons across the membrane
GVI67_RS21775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GVI67_RS21780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GVI67_RS21785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GVI67_RS21795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GVI67_RS21800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GVI67_RS21805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GVI67_RS21815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GVI67_RS21820	COG0573	inorganic phosphate transmembrane transporter activity
GVI67_RS21825	COG0581	inorganic phosphate transmembrane transporter activity
GVI67_RS21830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GVI67_RS21835	COG0704	Plays a role in the regulation of phosphate uptake
GVI67_RS21840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GVI67_RS21845	COG2252	PERMEase
GVI67_RS21850	COG0431	NADPH-dependent FMN reductase
GVI67_RS21855	COG2091	lysine biosynthetic process via aminoadipic acid
GVI67_RS21870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GVI67_RS21875	COG0706	membrane insertase activity
GVI67_RS21960	COG1192	Involved in chromosome partitioning
GVI67_RS22095	COG0210	DNA helicase
GVI67_RS22235	COG4245	von Willebrand factor, type A
GVI67_RS22240	COG4245	von Willebrand factor, type A
GVI67_RS22270	COG1358	cellular component organization or biogenesis
GVI67_RS22375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GVI67_RS22405	COG0789	Transcriptional regulator
GVI67_RS22445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GVI67_RS22490	COG3550	peptidyl-serine autophosphorylation
GVI67_RS22545	COG3039	Transposase
GVI67_RS22590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GVI67_RS22900	COG0659	secondary active sulfate transmembrane transporter activity
GVI67_RS22905	COG0589	response to stress
GVI67_RS22910	COG1393	Belongs to the ArsC family
GVI67_RS22915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GVI67_RS22920	COG0640	Transcriptional regulator
GVI67_RS22925	COG0431	NADPH-dependent FMN reductase
GVI67_RS22930	COG2801	Transposase and inactivated derivatives
GVI67_RS22960	COG2801	Transposase and inactivated derivatives
GVI67_RS22990	COG3039	Transposase
GVI67_RS23030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI67_RS23030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GVI67_RS23050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GVI67_RS23065	COG3157	Type VI secretion system effector, Hcp
GVI67_RS23410	COG2890	protein-(glutamine-N5) methyltransferase activity
GVI67_RS23470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GVI67_RS23505	COG2814	Major facilitator Superfamily
GVI67_RS23525	COG1280	lysine exporter protein (LysE YggA)
GVI67_RS23530	COG2200	EAL domain
GVI67_RS23535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GVI67_RS23535	COG0321	lipoyl(octanoyl) transferase activity
GVI67_RS23555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GVI67_RS23560	COG0768	penicillin binding
GVI67_RS23620	COG2135	peptidase activity
GVI67_RS23685	COG0489	protein tyrosine kinase activity
GVI67_RS23950	COG2805	Type II/IV secretion system protein
GVI67_RS24000	COG0741	lytic transglycosylase activity
GVI67_RS24015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GVI67_RS24105	COG3344	reverse transcriptase
GVI67_RS24180	COG3173	Aminoglycoside phosphotransferase
GVI67_RS24205	COG1695	Transcriptional regulator
GVI67_RS24270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GVI67_RS24360	COG3093	addiction module antidote protein HigA
GVI67_RS24390	COG3549	Plasmid maintenance system killer