locus-tag	class	description
HV033_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HV033_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HV033_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV033_RS00035	ENOG4105CC0	LysR family Transcriptional regulator
HV033_RS00045	ENOG410667J	hydrolase
HV033_RS00050	ENOG4105EMF	GntR family transcriptional regulator
HV033_RS00055	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
HV033_RS00060	ENOG4108RTU	Aldolase
HV033_RS00065	ENOG4105CXK	mandelate racemase muconate lactonizing
HV033_RS00070	ENOG4105DJB	Major Facilitator Superfamily
HV033_RS00075	ENOG4105D99	atp gtp-binding protein
HV033_RS00080	ENOG4105R2A	(LipO)protein
HV033_RS00090	ENOG4108SHS	Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity)
HV033_RS00095	ENOG4105D0C	transport protein
HV033_RS00100	ENOG4105FDP	GntR family transcriptional regulator
HV033_RS00105	ENOG4105CI1	PTS System
HV033_RS00110	ENOG4105F8D	glycoside hydrolase family 4
HV033_RS00115	ENOG4105VG5	Membrane
HV033_RS00120	ENOG4105JP4	Inner membrane protein yidG
HV033_RS00125	ENOG4105BZC	d-serine deaminase
HV033_RS00135	ENOG4105E5M	Multidrug resistance protein D
HV033_RS00160	ENOG4108Z3N	Transcriptional regulator
HV033_RS00170	ENOG4105C7K	acetolactate synthase
HV033_RS00175	ENOG4105M71	acetolactate synthase 1 regulatory subunit
HV033_RS00180	ENOG4108KX4	response regulator
HV033_RS00185	ENOG4105BZU	Histidine kinase
HV033_RS00190	ENOG4105CXY	transporter
HV033_RS00195	ENOG4105CXY	transporter
HV033_RS00200	ENOG4105CPT	Alpha beta hydrolase
HV033_RS00205	ENOG4108SAJ	Protein of unknown function (DUF1198)
HV033_RS00215	ENOG4108UZ3	Transporter
HV033_RS00220	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HV033_RS00225	ENOG4105VCP	PTS System
HV033_RS00230	ENOG4105CS2	ec 3.2.1.21
HV033_RS00235	ENOG4105CK1	PTS System
HV033_RS00245	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS00255	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HV033_RS00260	ENOG4105BZS	acriflavin resistance protein
HV033_RS00265	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HV033_RS00270	ENOG41067SE	Tetr family transcriptional regulator
HV033_RS00275	ENOG4105VEV	-acetyltransferase
HV033_RS00280	ENOG4107XI7	Tetr family transcriptional regulator
HV033_RS00290	ENOG4105D01	(LipO)protein
HV033_RS00315	ENOG4105CW0	outer membrane usher protein
HV033_RS00320	ENOG4108MQF	Chaperone
HV033_RS00350	ENOG4108N3D	putative enzyme
HV033_RS00375	ENOG4108JJA	ABC, transporter
HV033_RS00385	ENOG4108MBX	Secretion Protein
HV033_RS00390	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HV033_RS00395	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HV033_RS00410	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HV033_RS00415	ENOG4107SEY	Conserved Protein
HV033_RS00420	ENOG4105VT2	5-hydroxyisourate hydrolase
HV033_RS00425	ENOG4108XDN	Transcriptional regulator
HV033_RS00445	ENOG4105CW0	outer membrane usher protein
HV033_RS00450	ENOG4106JJN	Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae
HV033_RS00455	ENOG4108RQP	Major type 1 subunit fimbrin
HV033_RS00475	ENOG4105ECQ	AraC Family Transcriptional Regulator
HV033_RS00505	ENOG4105CT4	transporter
HV033_RS00510	ENOG4105CJQ	hydrolase, family 31
HV033_RS00515	ENOG4105JV1	AsmA family
HV033_RS00520	ENOG4105C2W	permease
HV033_RS00525	ENOG4105D6U	Sodium Glutamate Symporter
HV033_RS00530	ENOG4105CB5	ATP-dependent DNA helicase recG
HV033_RS00535	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HV033_RS00540	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HV033_RS00555	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HV033_RS00560	ENOG4105EN6	Membrane
HV033_RS00565	ENOG4105DSJ	YicC domain protein
HV033_RS00570	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HV033_RS00575	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HV033_RS00585	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HV033_RS00590	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HV033_RS00595	ENOG4105W5Q	DNA repair protein (RadC
HV033_RS00600	ENOG4105KDC	50s ribosomal protein l28
HV033_RS00605	ENOG4105W0E	50S ribosomal protein L33
HV033_RS00610	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HV033_RS00615	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HV033_RS00620	ENOG4106WTF	Glycosyl transferase, family 2
HV033_RS00625	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HV033_RS00630	ENOG4105K64	Glycosyl transferase, family 2
HV033_RS00635	ENOG4105CPK	Glycosyl transferase (Group 1
HV033_RS00645	ENOG4105DKP	glycosyl transferase, family 9
HV033_RS00670	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HV033_RS00675	ENOG4105XA0	heptosyltransferase ii
HV033_RS00680	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HV033_RS00685	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HV033_RS00690	ENOG4105CPQ	Dehydrogenase
HV033_RS00705	ENOG4106WTF	Glycosyl transferase, family 2
HV033_RS00710	ENOG4105PXI	polysaccharide deacetylase
HV033_RS00715	ENOG41063SB	peptidase
HV033_RS00720	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HV033_RS00725	ENOG4107YZP	Rhodanese domain protein
HV033_RS00730	ENOG4105VW4	glutaredoxin 3
HV033_RS00735	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HV033_RS00740	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HV033_RS00745	ENOG4105D7W	serine acetyltransferase
HV033_RS00750	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HV033_RS00755	ENOG4105C4R	Atp-dependent dna helicase
HV033_RS00760	ENOG4105C9X	ppx gppa phosphatase
HV033_RS00775	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HV033_RS00780	ENOG4105ESV	Glycosyl transferase, family 4
HV033_RS00785	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HV033_RS00790	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HV033_RS00795	ENOG4107QQG	Dehydrogenase
HV033_RS00800	ENOG4108WJ1	acetyltransferase
HV033_RS00805	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HV033_RS00810	ENOG4105EGZ	biosynthesis protein
HV033_RS00815	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HV033_RS00820	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
HV033_RS00825	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HV033_RS00830	ENOG4105C85	amino acid
HV033_RS00855	ENOG410601J	HemY protein
HV033_RS00860	ENOG4105ECF	c-methyltransferase
HV033_RS00865	ENOG41076E6	Uroporphyrinogen-III Synthase
HV033_RS00870	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HV033_RS00875	ENOG4107T0K	Adenylate cyclase
HV033_RS00885	ENOG4105S7Z	(LipO)protein
HV033_RS00895	ENOG4105CT0	Protein of unknown function, DUF484
HV033_RS00900	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HV033_RS00905	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HV033_RS00910	ENOG4105C4R	Atp-dependent dna helicase
HV033_RS00915	ENOG4107QUT	magnesium and cobalt transport protein CorA
HV033_RS00920	ENOG4105FR1	rard protein
HV033_RS00925	ENOG4108VUY	thioesterase Superfamily protein
HV033_RS00930	ENOG4105HDD	phospholipase
HV033_RS00935	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HV033_RS00940	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HV033_RS00945	ENOG410829K	Lysine exporter protein (Lyse ygga)
HV033_RS00950	ENOG4108EUD	Lysophospholipase
HV033_RS00955	ENOG4105DQF	Hydrolase
HV033_RS00960	ENOG4105EMK	carboxylate amino acid amine transporter
HV033_RS00965	ENOG4105DZ2	Transcriptional regulator
HV033_RS00975	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HV033_RS00980	ENOG4107SXA	Phosphorylase
HV033_RS00985	ENOG4105CGY	Dna recombination protein
HV033_RS00990	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HV033_RS00995	ENOG4105JC1	sterol-binding domain protein
HV033_RS01000	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HV033_RS01005	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HV033_RS01010	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HV033_RS01015	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HV033_RS01020	ENOG4105F8V	Hydrolase, tatD family
HV033_RS01025	ENOG4105MDZ	Transcriptional activator rfaH
HV033_RS01030	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HV033_RS01035	ENOG4107QK7	reductase
HV033_RS01040	ENOG4105C5H	ABC transporter
HV033_RS01045	ENOG4105MVF	Transcriptional regulator
HV033_RS01050	ENOG4106JH6	(LipO)protein
HV033_RS01060	ENOG4105C5I	Dehydrogenase
HV033_RS01070	ENOG4105D7K	pfkb domain protein
HV033_RS01080	ENOG4108M60	Transcriptional regulator
HV033_RS01085	ENOG4108ZG0	Ompa motb domain protein
HV033_RS01090	ENOG4107QY8	reductase
HV033_RS01095	ENOG4105HNP	-acetyltransferase
HV033_RS01100	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HV033_RS01105	ENOG4105EAX	Putative lipase
HV033_RS01110	ENOG4105FCD	Major Facilitator
HV033_RS01115	ENOG4105DIJ	Phosphoethanolamine transferase
HV033_RS01125	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV033_RS01130	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HV033_RS01135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV033_RS01140	ENOG4105C3U	ABC transporter
HV033_RS01145	ENOG4108JQ7	(ABC) transporter
HV033_RS01150	ENOG4105CS9	pantothenic acid kinase
HV033_RS01175	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HV033_RS01180	ENOG4105PM1	preprotein translocase subunit SecE
HV033_RS01185	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HV033_RS01200	ENOG4108VZM	50s ribosomal protein L10
HV033_RS01210	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HV033_RS01215	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HV033_RS01230	ENOG4106TD9	Diguanylate cyclase
HV033_RS01235	ENOG4105D41	biosynthesis protein thiH
HV033_RS01240	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HV033_RS01245	ENOG4105WHD	thiamine biosynthesis protein ThiS
HV033_RS01250	ENOG4105D06	uba thif-type nad fad binding protein
HV033_RS01255	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HV033_RS01260	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HV033_RS01265	ENOG4107MNS	Has binding activity to the major sigma subunit of RNA polymerase. May be involved in replacement of the RNA polymerase sigma subunit from sigma-70 to sigma-S during the transition from exponential growth to the stationary phase (By similarity)
HV033_RS01275	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HV033_RS01280	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HV033_RS01285	ENOG4105R2J	Conserved Protein
HV033_RS01290	ENOG4105K70	DNA-binding protein
HV033_RS01295	ENOG4108T8B	Protein of unknown function (DUF1481)
HV033_RS01300	ENOG4105C12	Phosphoribosylglycinamide synthetase
HV033_RS01305	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HV033_RS01325	ENOG4105CVG	Homoserine O-transsuccinylase
HV033_RS01330	ENOG4107QP3	malate synthase g
HV033_RS01335	ENOG4108I9X	Isocitrate lyase
HV033_RS01340	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HV033_RS01345	ENOG41069M3	Transcriptional regulator
HV033_RS01350	ENOG4105C3R	Methionine synthase
HV033_RS01355	ENOG4105EAM	Na Pi-cotransporter
HV033_RS01370	ENOG4105FE9	pseudouridine synthase
HV033_RS01375	ENOG4108ZR5	Conserved Protein
HV033_RS01380	ENOG4105C09	Bile acid
HV033_RS01385	ENOG4105CFH	Aspartokinase
HV033_RS01400	ENOG4108MDC	(LipO)protein
HV033_RS01405	ENOG4108Q9C	Periplasmic Protein
HV033_RS01410	ENOG4105E3R	(LipO)protein
HV033_RS01415	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HV033_RS01420	ENOG4105EG2	ABC transporter, permease
HV033_RS01425	ENOG4105D56	permease protein
HV033_RS01430	ENOG4107FKK	extracellular solute-binding protein family 1
HV033_RS01435	ENOG4108IJ9	(ABC) transporter
HV033_RS01445	ENOG4107W52	maltose operon periplasmic protein
HV033_RS01450	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HV033_RS01455	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HV033_RS01460	ENOG4105E55	glycerol-3-phosphate acyltransferase
HV033_RS01465	ENOG41080IJ	Diacylglycerol kinase
HV033_RS01470	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HV033_RS01475	ENOG4107R73	Mate efflux family protein
HV033_RS01480	ENOG4105VDW	Csbd family
HV033_RS01485	ENOG4105MYN	Zinc uptake regulation protein
HV033_RS01500	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HV033_RS01505	ENOG4105P4Z	Phage shock protein G
HV033_RS01510	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HV033_RS01515	ENOG4105CDU	Replicative dna helicase
HV033_RS01520	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HV033_RS01525	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HV033_RS01530	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HV033_RS01535	ENOG4105CGF	Aromatic amino acid aminotransferase
HV033_RS01540	ENOG4105F0S	class B acid phosphatase
HV033_RS01545	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HV033_RS01550	ENOG4105MSB	protein, conserved in bacteria
HV033_RS01555	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HV033_RS01560	ENOG4108UUM	single-stranded DNA-binding protein
HV033_RS01565	ENOG4108FPN	Integrase
HV033_RS01625	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HV033_RS01655	ENOG4105PMV	Membrane
HV033_RS01665	ENOG4108M8H	domain protein
HV033_RS01670	ENOG4108W3Q	Transcriptional regulator
HV033_RS01675	ENOG4108Z4X	TRANSCRIPTIONal
HV033_RS01680	ENOG4108K3A	Glutathione S-transferase
HV033_RS01685	ENOG4105C7N	Xanthine uracil vitamin C permease
HV033_RS01690	ENOG4105EEQ	Na H antiporter
HV033_RS01695	ENOG4105CMU	LysR family (Transcriptional regulator
HV033_RS01700	ENOG4105VAW	lrga family
HV033_RS01705	ENOG41067MG	lrgb family
HV033_RS01710	ENOG4107QN1	sodium solute
HV033_RS01715	ENOG41062QD	Membrane
HV033_RS01720	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HV033_RS01725	ENOG4105CK2	sodium dicarboxylate symporter
HV033_RS01730	ENOG41082ND	Uncharacterized protein yjcO
HV033_RS01735	ENOG41074AV	Hok/gef family
HV033_RS01760	ENOG4105D2N	Aldolase
HV033_RS01770	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HV033_RS01775	ENOG4105CNN	ABC, transporter
HV033_RS01780	ENOG4105C2J	ABC transporter
HV033_RS01785	ENOG4105BZU	Histidine kinase
HV033_RS01795	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
HV033_RS01800	ENOG410849A	acetyltransferase, (GNAT) family
HV033_RS01805	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HV033_RS01810	ENOG4105FD8	phosphonate metabolism protein PhnM
HV033_RS01815	ENOG4105HRV	phosphonate c-p lyase system protein phnl
HV033_RS01820	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
HV033_RS01825	ENOG4105FT8	Phosphonate metabolism
HV033_RS01830	ENOG4105EKV	Phosphonate metabolism protein
HV033_RS01835	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
HV033_RS01840	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
HV033_RS01845	ENOG4107RJJ	Transcriptional regulator
HV033_RS01855	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
HV033_RS01860	ENOG4105D5T	phosphonate abc transporter
HV033_RS01865	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HV033_RS01870	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HV033_RS01875	ENOG4108F5E	vimentin
HV033_RS01880	ENOG4108YIV	
HV033_RS01885	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HV033_RS01890	ENOG4105CSH	Transporter
HV033_RS01895	ENOG4105D7X	high-affinity nickel-transporter
HV033_RS01995	ENOG4108SIC	Transcriptional regulator
HV033_RS02000	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HV033_RS02010	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HV033_RS02015	ENOG4108IJ0	Aspartate ammonia-lyase
HV033_RS02020	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
HV033_RS02025	ENOG4105DVH	amino acid
HV033_RS02040	ENOG4108P2H	Inner membrane protein YjiG
HV033_RS02045	ENOG41074DU	domain protein
HV033_RS02050	ENOG4108ZVF	(LipO)protein
HV033_RS02055	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HV033_RS02060	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HV033_RS02070	ENOG4106BSU	Entericidin B
HV033_RS02090	ENOG4106FGB	Beta-lactamase
HV033_RS02095	ENOG4105ETT	transcriptional Regulator, LysR family
HV033_RS02105	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HV033_RS02110	ENOG4105E33	succinate dehydrogenase
HV033_RS02115	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HV033_RS02120	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HV033_RS02125	ENOG4107SC7	Inner membrane transporter yjeM
HV033_RS02130	ENOG4105EGS	Mechanosensitive ion channel
HV033_RS02165	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HV033_RS02170	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HV033_RS02175	ENOG4105K8N	protein family UPF0079, ATPase
HV033_RS02180	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HV033_RS02185	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HV033_RS02190	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HV033_RS02195	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HV033_RS02200	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HV033_RS02205	ENOG4107QJR	hflk protein
HV033_RS02210	ENOG4105EPW	hflc protein
HV033_RS02225	ENOG4105KPV	Transcriptional regulator
HV033_RS02230	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HV033_RS02235	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HV033_RS02240	ENOG4105CSH	Transporter
HV033_RS02245	ENOG4105CSU	acyl-Coa dehydrogenase
HV033_RS02250	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS02255	ENOG4105S17	UPF0379 protein yjfN
HV033_RS02260	ENOG4105WSB	biofilm stress and motility protein A
HV033_RS02265	ENOG4108MXZ	Esterase
HV033_RS02280	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HV033_RS02310	ENOG4105KIT	UPF0379 protein yjfY
HV033_RS02315	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HV033_RS02320	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HV033_RS02325	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HV033_RS02330	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HV033_RS02335	ENOG4108IPJ	Membrane
HV033_RS02340	ENOG4105FHY	Opacity-associated protein A
HV033_RS02345	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HV033_RS02355	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HV033_RS02360	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS02365	ENOG4105DXC	membrane
HV033_RS02375	ENOG4105BZU	Histidine kinase
HV033_RS02385	ENOG4108WQH	regulatoR
HV033_RS02405	ENOG4105ECR	NmrA family
HV033_RS02410	ENOG4105KVH	Transcriptional regulator
HV033_RS02415	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HV033_RS02420	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HV033_RS02425	ENOG4108UUE	Transcriptional regulator
HV033_RS02430	ENOG41061GZ	Protein of unknown function (DUF1107)
HV033_RS02435	ENOG4105C37	(CBS) domain
HV033_RS02440	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HV033_RS02445	ENOG4105CFU	surface antigen
HV033_RS02450	ENOG4105MA0	exported protein
HV033_RS02455	ENOG4108ZHD	aig2 family
HV033_RS02470	ENOG4105F0N	pyrophosphate phospho-hydrolase
HV033_RS02475	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HV033_RS02480	ENOG4105C2J	ABC transporter
HV033_RS02485	ENOG4107R9N	ABC transporter
HV033_RS02490	ENOG41062B0	ABC transporter, permease
HV033_RS02495	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS02505	ENOG4105DFU	Cell wall formation (By similarity)
HV033_RS02510	ENOG4105N42	UPF0307 protein
HV033_RS02515	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HV033_RS02520	ENOG4108XVM	Cytochrome b(562)
HV033_RS02550	ENOG41069H0	dihydroorotase EC 3.5.2.3
HV033_RS02570	ENOG4105EMD	TRANSCRIPTIONal
HV033_RS02575	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HV033_RS02580	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HV033_RS02585	ENOG4105DM4	PTS System
HV033_RS02590	ENOG4105C8I	hydrolase, family 38
HV033_RS02595	ENOG410863U	PTS System
HV033_RS02600	ENOG4106KNT	transcriptional regulator
HV033_RS02610	ENOG4105CG3	alpha amylase, catalytic region
HV033_RS02615	ENOG4105C5Y	PTS System
HV033_RS02620	ENOG4105D4X	repressor
HV033_RS02630	ENOG4105E2D	ec 3.2.1.52
HV033_RS02635	ENOG4108M1A	Chitin-binding protein
HV033_RS02640	ENOG4105KME	endoribonuclease L-psp
HV033_RS02645	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HV033_RS02650	ENOG4105CXT	aspartate transcarbamylase
HV033_RS02655	ENOG41077AM	PyrBI operon attenuator
HV033_RS02665	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HV033_RS02670	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HV033_RS02675	ENOG4105DBV	ornithine carbamoyltransferase
HV033_RS02680	ENOG4105C5B	carbamate kinase
HV033_RS02685	ENOG4105CEU	Arginine dihydrolase
HV033_RS02690	ENOG4105XEP	YhcH YjgK YiaL family protein
HV033_RS02695	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HV033_RS02700	ENOG4105C01	Dihydroxy-acid dehydratase
HV033_RS02705	ENOG4105CT4	transporter
HV033_RS02710	ENOG4105DSG	hydrolase family 43
HV033_RS02715	ENOG4107HP6	Transcriptional regulator
HV033_RS02720	ENOG4105DBV	ornithine carbamoyltransferase
HV033_RS02725	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HV033_RS02730	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HV033_RS02765	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HV033_RS02975	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS02985	ENOG4105CT4	transporter
HV033_RS03010	ENOG4105CHJ	isochorismatase hydrolase
HV033_RS03030	ENOG4105BZU	Histidine kinase
HV033_RS03035	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HV033_RS03040	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HV033_RS03045	ENOG4105EZE	Cupin 4 family protein
HV033_RS03070	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HV033_RS03075	ENOG4106DIZ	Domain of unknown function (DUF1127)
HV033_RS03085	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HV033_RS03100	ENOG4108ZHR	arsR family transcriptional regulator
HV033_RS03120	ENOG4106BRA	Membrane
HV033_RS03130	ENOG4106AXJ	AraC family transcriptional regulator
HV033_RS03135	ENOG4105C26	Dehydrogenase
HV033_RS03155	ENOG4105CKI	cobalamin synthesis protein
HV033_RS03160	ENOG4105VCD	cytoplasmic protein
HV033_RS03165	ENOG4105D22	carbon starvation protein
HV033_RS03170	ENOG4105YW5	deoR family transcriptional regulator
HV033_RS03175	ENOG4107UWN	reductase
HV033_RS03180	ENOG4105EFA	4-hydroxyphenylacetate
HV033_RS03195	ENOG4105CNV	Aldolase
HV033_RS03210	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
HV033_RS03215	ENOG4105C26	Dehydrogenase
HV033_RS03220	ENOG4105ERH	Fumarylacetoacetate hydrolase
HV033_RS03225	ENOG4108V8F	Transcriptional regulator, MarR family
HV033_RS03230	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS03235	ENOG4105XYF	acetyltransferase
HV033_RS03240	ENOG4107RES	phosphoglycerol transferase I
HV033_RS03245	ENOG4105RI1	glycoprotein receptor
HV033_RS03250	ENOG4106CVF	DNA replication protein
HV033_RS03255	ENOG4108PM0	it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity)
HV033_RS03260	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HV033_RS03265	ENOG4105K56	Transcriptional regulator
HV033_RS03270	ENOG4107XM3	UPF0442 protein
HV033_RS03275	ENOG4105DWK	Membrane
HV033_RS03280	ENOG4108N8T	regulatoR
HV033_RS03285	ENOG4108T94	DNA-binding transcriptional activator BglJ
HV033_RS03290	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HV033_RS03295	ENOG4105CK1	PTS System
HV033_RS03300	ENOG4108819	ferric iron reductase
HV033_RS03305	ENOG4106TD9	Diguanylate cyclase
HV033_RS03310	ENOG4105YBH	Protein of unknown function (DUF1435)
HV033_RS03330	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HV033_RS03335	ENOG4108WPU	DNA polymerase III subunit psi
HV033_RS03340	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HV033_RS03345	ENOG4105PAD	Hydrolase
HV033_RS03350	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HV033_RS03355	ENOG4105K3G	Periplasmic Protein
HV033_RS03365	ENOG4108NRW	Phospholipase, patatin family
HV033_RS03370	ENOG4105EYA	deoxyribonuclease
HV033_RS03375	ENOG41076CZ	activating enzyme
HV033_RS03380	ENOG4105G0K	glycine radical enzyme YjjI family
HV033_RS03390	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HV033_RS03400	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HV033_RS03405	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HV033_RS03410	ENOG41062Z9	Membrane
HV033_RS03415	ENOG4105EAC	phosphoserine phosphatase
HV033_RS03420	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HV033_RS03425	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HV033_RS03440	ENOG4105C5H	ABC transporter
HV033_RS03445	ENOG4107SC1	transglycosylase
HV033_RS03450	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HV033_RS03455	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HV033_RS03460	ENOG4105CVJ	phosphoglycerate mutase
HV033_RS03465	ENOG4105UEI	Transcriptional Regulator AraC Family
HV033_RS03470	ENOG4108RH0	Crea protein
HV033_RS03475	ENOG41065U4	response regulator
HV033_RS03480	ENOG410759A	
HV033_RS03485	ENOG4106FVC	RNA methyltransferase
HV033_RS03495	ENOG4105CFH	Aspartokinase
HV033_RS03505	ENOG4105D98	threonine synthase
HV033_RS03510	ENOG41062C6	Protein of unknown function (DUF2502)
HV033_RS03515	ENOG4105D1Q	UPF0246 protein
HV033_RS03520	ENOG4105BZG	amino acid carrier protein
HV033_RS03525	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HV033_RS03530	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HV033_RS03535	ENOG4105CSH	Transporter
HV033_RS03540	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HV033_RS03545	ENOG4105CFG	Acts as a chaperone (By similarity)
HV033_RS03555	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HV033_RS03560	ENOG41063Z6	transcriptional regulator, lysR family
HV033_RS03565	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HV033_RS03570	ENOG4105DTN	riboflavin biosynthesis protein ribF
HV033_RS03575	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HV033_RS03585	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HV033_RS03590	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HV033_RS03600	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HV033_RS03605	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HV033_RS03610	ENOG4105M5B	(LipO)protein
HV033_RS03615	ENOG4106AS2	Outer membrane autotransporter
HV033_RS03620	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HV033_RS03625	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HV033_RS03630	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HV033_RS03635	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HV033_RS03640	ENOG4105NWN	ApaG protein
HV033_RS03645	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HV033_RS03650	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HV033_RS03655	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HV033_RS03660	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HV033_RS03665	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HV033_RS03670	ENOG4105D3G	Pseudouridine synthase
HV033_RS03675	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HV033_RS03680	ENOG4105CQ2	DNA polymerase
HV033_RS03685	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HV033_RS03690	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HV033_RS03695	ENOG4105EF1	ribulokinase
HV033_RS03705	ENOG4108KF1	Membrane
HV033_RS03715	ENOG4106SMU	thiamine transporter membrane protein
HV033_RS03735	ENOG4105S8Q	sugar efflux transporter
HV033_RS03740	ENOG41060TC	Hok gef cell toxic protein
HV033_RS03745	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HV033_RS03750	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HV033_RS03755	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HV033_RS03760	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HV033_RS03775	ENOG4105F2I	Transposase
HV033_RS03810	ENOG4105F9F	transposase
HV033_RS03815	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS03840	ENOG4108C33	Resolvase
HV033_RS03845	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS03875	ENOG4108T1W	Fimbrial subunit type 3
HV033_RS03885	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS03890	ENOG4105F2I	Transposase
HV033_RS03895	ENOG4105RVE	Uncharacterized protein conserved in bacteria (DUF2136)
HV033_RS03900	ENOG4108Z3N	Transcriptional regulator
HV033_RS03920	ENOG4108YXQ	IS66 Orf2 family protein
HV033_RS03925	ENOG4105E5H	Transposase
HV033_RS03940	ENOG4105F2I	Transposase
HV033_RS03950	ENOG4106ECQ	phosphomannomutase
HV033_RS03960	ENOG4105E2K	Glycosyl transferase (Group 1
HV033_RS03985	ENOG4105ER6	polysaccharide biosynthesis protein
HV033_RS03995	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HV033_RS04000	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HV033_RS04005	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HV033_RS04010	ENOG4105G1A	colanic acid biosynthesis protein
HV033_RS04015	ENOG4107T8Q	Glycosyl transferase (Group 1
HV033_RS04080	ENOG4106JVB	Replication Protein
HV033_RS04125	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS04170	ENOG4108BUD	transposase
HV033_RS04180	ENOG4105X54	addiction module antidote protein
HV033_RS04195	ENOG4108BUD	transposase
HV033_RS04205	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HV033_RS04210	ENOG4108BUD	transposase
HV033_RS04230	ENOG4105ESV	Glycosyl transferase, family 4
HV033_RS04235	ENOG4105F2I	Transposase
HV033_RS04240	ENOG4108VEV	chaperone
HV033_RS04245	ENOG4105CW0	outer membrane usher protein
HV033_RS04250	ENOG4108XEY	fimbrial-like adhesin protein
HV033_RS04260	ENOG4105SN2	fimbrial-like adhesin protein
HV033_RS04270	ENOG4107BJW	polysaccharide deacetylase
HV033_RS04275	ENOG4108YTN	IIa component
HV033_RS04280	ENOG4105E3A	(ABC) transporter
HV033_RS04285	ENOG4105DA5	(ABC) transporter
HV033_RS04290	ENOG41077A9	carbonic anhydrase
HV033_RS04295	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HV033_RS04300	ENOG4105DZG	Dehydrogenase
HV033_RS04310	ENOG4108ZRK	uncharacterized protein yacC
HV033_RS04315	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HV033_RS04320	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HV033_RS04330	ENOG4107QIJ	Aconitate hydratase 2
HV033_RS04335	ENOG4108NST	exported protein
HV033_RS04345	ENOG4107QN2	dihydrolipoyl dehydrogenase
HV033_RS04350	ENOG4107QSN	dihydrolipoamide acetyltransferase
HV033_RS04355	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HV033_RS04360	ENOG41073TP	transcriptional regulator
HV033_RS04365	ENOG4105C85	amino acid
HV033_RS04370	ENOG4105CT4	transporter
HV033_RS04375	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HV033_RS04380	ENOG4106A72	regulatory protein AmpE
HV033_RS04385	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HV033_RS04390	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HV033_RS04395	ENOG4108ZUW	Major pilin subunit
HV033_RS04400	ENOG4107QHF	type ii secretion system protein e
HV033_RS04405	ENOG4105D7Q	type ii secretion system
HV033_RS04410	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HV033_RS04415	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HV033_RS04420	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HV033_RS04425	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HV033_RS04430	ENOG4105M6F	mutator MutT protein
HV033_RS04435	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HV033_RS04440	ENOG4106Q9Y	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HV033_RS04445	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV033_RS04450	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HV033_RS04455	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HV033_RS04460	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HV033_RS04465	ENOG4105CPF	Cell wall formation (By similarity)
HV033_RS04470	ENOG4105DFU	Cell wall formation (By similarity)
HV033_RS04475	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HV033_RS04480	ENOG4105CNI	cell division protein FtsW
HV033_RS04490	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HV033_RS04495	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HV033_RS04500	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HV033_RS04505	ENOG4105CJN	penicillin-binding protein
HV033_RS04510	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HV033_RS04520	ENOG4108V6E	Cell division protein mraZ
HV033_RS04525	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HV033_RS04530	ENOG4108ZP8	Acetolactate synthase small subunit
HV033_RS04535	ENOG4105C7K	acetolactate synthase
HV033_RS04540	ENOG41064T2	transcriptional regulator, lysR family
HV033_RS04545	ENOG4105F2I	Transposase
HV033_RS04560	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HV033_RS04565	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HV033_RS04570	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HV033_RS04575	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV033_RS04580	ENOG4105DJ0	Poly(A) Polymerase
HV033_RS04585	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HV033_RS04590	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV033_RS04595	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HV033_RS04600	ENOG4107XID	2'-5' rna ligase
HV033_RS04605	ENOG4105CQ7	ATP-dependent helicase
HV033_RS04610	ENOG4105BZ4	penicillin-binding protein
HV033_RS04615	ENOG4105E0K	tonB-dependent siderophore receptor
HV033_RS04620	ENOG4105E0A	ABC, transporter
HV033_RS04625	ENOG4105J76	Periplasmic binding protein
HV033_RS04630	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HV033_RS04635	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HV033_RS04640	ENOG4105CMQ	Chloride channel
HV033_RS04645	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HV033_RS04650	ENOG4105EN6	Membrane
HV033_RS04660	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HV033_RS04665	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HV033_RS04670	ENOG4105C0H	protease
HV033_RS04675	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HV033_RS04680	ENOG4108T8E	UPF0325 protein
HV033_RS04685	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HV033_RS04690	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HV033_RS04695	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HV033_RS04700	ENOG4105CE9	30S ribosomal protein S2
HV033_RS04705	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HV033_RS04710	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HV033_RS04720	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HV033_RS04730	ENOG4105KNE	Phosphatidate cytidylyltransferase
HV033_RS04735	ENOG4105DZP	Membrane-associated zinc metalloprotease
HV033_RS04740	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV033_RS04745	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HV033_RS04750	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV033_RS04755	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HV033_RS04760	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV033_RS04765	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HV033_RS04770	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HV033_RS04775	ENOG4105C0B	DNA polymerase III (alpha subunit)
HV033_RS04780	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HV033_RS04785	ENOG4105CXN	decarboxylase
HV033_RS04790	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HV033_RS04795	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HV033_RS04800	ENOG4105M1T	rho-binding antiterminator
HV033_RS04805	ENOG4105W1I	UPF0253 protein
HV033_RS04810	ENOG4108VWS	Yaeq family
HV033_RS04815	ENOG4108YZN	class I peptide chain release factor
HV033_RS04820	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HV033_RS04825	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HV033_RS04830	ENOG4108R96	Methyltransferase, YaeB family
HV033_RS04835	ENOG4108R8X	outer membrane lipoprotein
HV033_RS04840	ENOG4105D01	(LipO)protein
HV033_RS04845	ENOG4108UMI	ABC transporter, permease
HV033_RS04850	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HV033_RS04855	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HV033_RS04890	ENOG4105CV8	reductase
HV033_RS04895	ENOG4105HEI	LysR family (Transcriptional regulator
HV033_RS04900	ENOG4105F27	Major Facilitator
HV033_RS04905	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HV033_RS04910	ENOG4105F2W	methyltransferase
HV033_RS04915	ENOG4105E9H	Lytic Murein transglycosylase
HV033_RS04920	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HV033_RS04925	ENOG4105D1A	Methyltransferase
HV033_RS04935	ENOG4107RZZ	dna polymerase iii epsilon subunit
HV033_RS04950	ENOG4105C3U	ABC transporter
HV033_RS04955	ENOG4108JQ7	(ABC) transporter
HV033_RS04970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV033_RS04975	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HV033_RS04980	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HV033_RS04985	ENOG4107QPN	acyl-Coa dehydrogenase
HV033_RS04995	ENOG4105E7A	Glutamine amidotransferase
HV033_RS05000	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HV033_RS05005	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV033_RS05015	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV033_RS05020	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV033_RS05025	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HV033_RS05030	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HV033_RS05040	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HV033_RS05045	ENOG4105CIN	aminoacyl-histidine dipeptidase
HV033_RS05050	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HV033_RS05055	ENOG4105V1F	Fermentation respiration switch protein
HV033_RS05065	ENOG4105FCK	Membrane
HV033_RS05070	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HV033_RS05075	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HV033_RS05130	ENOG4105DFP	Integrase
HV033_RS05170	ENOG4105CGD	Nad-dependent epimerase dehydratase
HV033_RS05175	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS05180	ENOG4107SET	aldo keto reductase
HV033_RS05220	ENOG4105GR3	Histidine kinase
HV033_RS05230	ENOG4105CPC	Aldo Keto reductase
HV033_RS05235	ENOG4105ENX	hydrolase
HV033_RS05240	ENOG4108TKH	Nitroreductase
HV033_RS05245	ENOG4105C2C	drug resistance transporter, Bcr CflA
HV033_RS05250	ENOG4105DTA	methyltransferase
HV033_RS05260	ENOG4105BZU	Histidine kinase
HV033_RS05280	ENOG4105F4G	Membrane
HV033_RS05285	ENOG4108IQI	permease
HV033_RS05290	ENOG4107QK5	Homocysteine s-methyltransferase
HV033_RS05295	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HV033_RS05300	ENOG4108ETV	ABC transporter
HV033_RS05305	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HV033_RS05310	ENOG4105E2B	Taurine dioxygenase
HV033_RS05320	ENOG4105D52	delta-aminolevulinic acid dehydratase
HV033_RS05325	ENOG4108NSE	outer membrane autotransporter barrel
HV033_RS05330	ENOG4108PNB	DNA-binding transcriptional regulator
HV033_RS05335	ENOG4107R6D	beta-lactam binding protein AmpH
HV033_RS05340	ENOG4108RWI	nicotinamidase
HV033_RS05345	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
HV033_RS05350	ENOG4107QS8	(LipO)protein
HV033_RS05355	ENOG4105FR5	inner membrane protein YaiY
HV033_RS05360	ENOG4105UNH	Membrane
HV033_RS05365	ENOG4105CPF	Cell wall formation (By similarity)
HV033_RS05380	ENOG4105RZQ	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity)
HV033_RS05385	ENOG4105VIF	phosphate starvation-inducible protein
HV033_RS05390	ENOG4105BZU	Histidine kinase
HV033_RS05395	ENOG4105II7	pyrroline-5-carboxylate reductase
HV033_RS05400	ENOG4108UPT	UPF0178 protein
HV033_RS05405	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HV033_RS05410	ENOG4105SS3	
HV033_RS05415	ENOG4105HBA	AroM protein
HV033_RS05420	ENOG4105NBK	UPF0345 protein
HV033_RS05430	ENOG4105DKQ	ROK family
HV033_RS05435	ENOG4105EYH	Exonuclease
HV033_RS05440	ENOG4107RH8	nuclease SbcCD subunit D
HV033_RS05450	ENOG4105BZU	Histidine kinase
HV033_RS05455	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HV033_RS05460	ENOG4105C85	amino acid
HV033_RS05465	ENOG4107R28	alpha amylase, catalytic region
HV033_RS05480	ENOG4105D3R	alkyl hydroperoxide reductase
HV033_RS05485	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HV033_RS05495	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HV033_RS05500	ENOG4105VIE	preprotein translocase, subunit YajC
HV033_RS05505	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HV033_RS05510	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HV033_RS05520	ENOG4105DRB	nucleoside-specific channel-forming protein
HV033_RS05525	ENOG4108KIC	(LipO)protein
HV033_RS05530	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HV033_RS05535	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HV033_RS05540	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HV033_RS05545	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HV033_RS05550	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HV033_RS05555	ENOG4105CPC	Aldo Keto reductase
HV033_RS05560	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HV033_RS05565	ENOG4105CTB	Polyprenyl synthetase
HV033_RS05570	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HV033_RS05580	ENOG4107S0N	DJ-1 family
HV033_RS05585	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HV033_RS05595	ENOG4107RDB	Major Facilitator
HV033_RS05600	ENOG4107W7X	Aldolase
HV033_RS05610	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HV033_RS05620	ENOG4105CNN	ABC, transporter
HV033_RS05625	ENOG4105C2J	ABC transporter
HV033_RS05630	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
HV033_RS05635	ENOG4105CMG	Carbohydrate kinase
HV033_RS05645	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HV033_RS05650	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HV033_RS05655	ENOG4105CCU	oxidase (Subunit III)
HV033_RS05660	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HV033_RS05665	ENOG4105E2S	oxidase) subunit II
HV033_RS05670	ENOG4105EYM	Major Facilitator superfamily
HV033_RS05675	ENOG4105IEY	(LipO)protein
HV033_RS05680	ENOG4105M85	Bola protein
HV033_RS05685	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HV033_RS05700	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HV033_RS05705	ENOG4105K70	DNA-binding protein
HV033_RS05710	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HV033_RS05715	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HV033_RS05720	ENOG4108TGP	Thioesterase superfamily protein
HV033_RS05725	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HV033_RS05730	ENOG4108NFA	extracellular solute-binding protein
HV033_RS05735	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HV033_RS05745	ENOG4108XM1	transcriptional regulator AsnC family
HV033_RS05750	ENOG4105BZ1	(ABC) transporter
HV033_RS05755	ENOG4105BZ1	(ABC) transporter
HV033_RS05760	ENOG4108YZA	Nitrogen regulatory protein pii
HV033_RS05765	ENOG4105BZU	Histidine kinase
HV033_RS05770	ENOG4105C29	acyl-CoA thioesterase
HV033_RS05775	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HV033_RS05780	ENOG41080UX	Methyltransferase
HV033_RS05800	ENOG4107U9B	transcriptional regulator
HV033_RS05805	ENOG4108VW9	Membrane
HV033_RS05810	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS05820	ENOG41066DG	(EAL) domain protein
HV033_RS05825	ENOG4105NRA	50s ribosomal protein l31 type b
HV033_RS05830	ENOG4105YK5	50S ribosomal protein L36
HV033_RS05845	ENOG4105GSJ	Inner membrane protein ylaC
HV033_RS05850	ENOG4108UW5	maltose o-acetyltransferase
HV033_RS05860	ENOG4108UKR	Biofilm formation regulator YbaJ
HV033_RS05865	ENOG4105BZS	acriflavin resistance protein
HV033_RS05870	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HV033_RS05875	ENOG4107XI7	Tetr family transcriptional regulator
HV033_RS05880	ENOG4105EGS	Mechanosensitive ion channel
HV033_RS05885	ENOG4106428	Protein of unknown function (DUF2496)
HV033_RS05890	ENOG4108URS	primosomal replication protein n''
HV033_RS05895	ENOG4105WD1	Membrane
HV033_RS05900	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HV033_RS05905	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HV033_RS05910	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HV033_RS05915	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HV033_RS05920	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HV033_RS05925	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HV033_RS05930	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HV033_RS05935	ENOG4107RE1	Inosine-guanosine kinase
HV033_RS05940	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HV033_RS05945	ENOG4105EU0	Major facilitator Superfamily
HV033_RS05950	ENOG4105CGH	5'-nucleotidase
HV033_RS05955	ENOG4108Z66	YbaK ebsC protein
HV033_RS05960	ENOG4105MBR	gumn family
HV033_RS05965	ENOG4105C59	p-type ATPase
HV033_RS05970	ENOG4108Z6Z	Transcriptional regulator
HV033_RS05975	ENOG4105G5H	Membrane
HV033_RS05980	ENOG4107QX8	SPFH domain, Band 7 family protein
HV033_RS05990	ENOG41083J0	(ABC) transporter
HV033_RS05995	ENOG4105C4B	ABC transporter, permease
HV033_RS06000	ENOG4107QR8	Thioredoxin
HV033_RS06005	ENOG4105E1F	short-chain dehydrogenase reductase
HV033_RS06010	ENOG4108UJV	acyl-CoA thioesterase i
HV033_RS06015	ENOG4108I0Y	(ABC) transporter
HV033_RS06020	ENOG4105CV6	ABC transporter, permease
HV033_RS06025	ENOG4105FCK	Membrane
HV033_RS06040	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HV033_RS06045	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HV033_RS06050	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HV033_RS06055	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HV033_RS06060	ENOG4105C8N	cysteinyl-tRNA synthetase
HV033_RS06065	ENOG4105S2T	inner membrane protein YbcI
HV033_RS06070	ENOG4107P2S	Transcriptional regulator
HV033_RS06075	ENOG4105CI1	PTS System
HV033_RS06080	ENOG4105WQ3	Rna-binding protein
HV033_RS06085	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HV033_RS06090	ENOG4108WDE	Fimbrial protein
HV033_RS06095	ENOG4105NJT	Fimbrial protein
HV033_RS06100	ENOG4108AF8	Chaperone
HV033_RS06105	ENOG4105CW0	outer membrane usher protein
HV033_RS06110	ENOG4108M66	Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity)
HV033_RS06115	ENOG4108ZI2	Fimbrial protein
HV033_RS06120	ENOG4108Q9V	regulatoR
HV033_RS06155	ENOG4105TDT	uncharacterized protein yahO
HV033_RS06170	ENOG4105C85	amino acid
HV033_RS06175	ENOG4105EAA	nucleoside
HV033_RS06195	ENOG4105CUY	Mechanosensitive ion channel
HV033_RS06215	ENOG4108RCM	Nitroreductase
HV033_RS06220	ENOG4105MSB	protein, conserved in bacteria
HV033_RS06225	ENOG41067SE	Tetr family transcriptional regulator
HV033_RS06235	ENOG4105SUT	Transcriptional Regulator AraC Family
HV033_RS06240	ENOG4105E0K	tonB-dependent siderophore receptor
HV033_RS06250	ENOG4105WQ6	Membrane
HV033_RS06260	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HV033_RS06275	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS06340	ENOG4105C7K	acetolactate synthase
HV033_RS06345	ENOG4105CHR	reductase
HV033_RS06375	ENOG4105C94	Transporter
HV033_RS06395	ENOG4105DIK	(ABC) transporter
HV033_RS06400	ENOG4105CC5	ABC transporter
HV033_RS06405	ENOG4105CC5	ABC transporter
HV033_RS06410	ENOG4108TSE	Transferase
HV033_RS06415	ENOG4107RNH	Outer membrane receptor FepA
HV033_RS06420	ENOG4105E93	esterase
HV033_RS06425	ENOG41085A6	mbth domain-containing protein
HV033_RS06430	ENOG4105C0W	non-ribosomal peptide synthetase
HV033_RS06435	ENOG4105E0A	ABC, transporter
HV033_RS06440	ENOG4105TVJ	transport system, permease
HV033_RS06445	ENOG4105DQ5	transport system permease protein
HV033_RS06450	ENOG4105E8G	Major facilitator Superfamily
HV033_RS06455	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HV033_RS06460	ENOG4105E4F	Isochorismate synthase
HV033_RS06465	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HV033_RS06470	ENOG4105WQI	isochorismatase
HV033_RS06475	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HV033_RS06480	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
HV033_RS06485	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HV033_RS06490	ENOG4108P2H	Inner membrane protein YjiG
HV033_RS06495	ENOG41074DU	domain protein
HV033_RS06500	ENOG4105D22	carbon starvation protein
HV033_RS06505	ENOG4105VCD	cytoplasmic protein
HV033_RS06520	ENOG4105CHR	reductase
HV033_RS06525	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HV033_RS06530	ENOG4105C2J	ABC transporter
HV033_RS06535	ENOG4105CNN	ABC, transporter
HV033_RS06550	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HV033_RS06555	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HV033_RS06565	ENOG4105HVQ	Regulatory factor of maltose metabolism
HV033_RS06575	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HV033_RS06580	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HV033_RS06585	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HV033_RS06590	ENOG4105CHM	Aminotransferase
HV033_RS06595	ENOG4105GTN	ParB Domain Protein Nuclease
HV033_RS06600	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HV033_RS06605	ENOG4105DQS	Transcriptional regulator
HV033_RS06610	ENOG4105D3R	alkyl hydroperoxide reductase
HV033_RS06615	ENOG4108JU3	Alkyl hydroperoxide reductase
HV033_RS06620	ENOG4108U51	Universal stress protein
HV033_RS06625	ENOG4105E2A	Dehydrogenase
HV033_RS06630	ENOG4105NXH	GreA GreB family elongation factor
HV033_RS06640	ENOG4105KTS	ribonuclease
HV033_RS06645	ENOG4105CEE	C4-dicarboxylate transporter
HV033_RS06665	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HV033_RS06675	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HV033_RS06695	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
HV033_RS06700	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HV033_RS06705	ENOG41064T2	transcriptional regulator, lysR family
HV033_RS06710	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HV033_RS06715	ENOG4108Z43	UPF0250 protein
HV033_RS06720	ENOG4105DZ1	carboxypeptidase
HV033_RS06725	ENOG4105K6T	rare lipoprotein A
HV033_RS06730	ENOG4105CNI	cell division protein FtsW
HV033_RS06735	ENOG4105CJN	penicillin-binding protein
HV033_RS06740	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HV033_RS06745	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HV033_RS06755	ENOG4105DJF	DNA polymerase III, delta' subunit
HV033_RS06765	ENOG4105C8T	Leucyl-tRNA synthetase
HV033_RS06770	ENOG4107PAI	alpha helical protein
HV033_RS06775	ENOG4105DU0	nucleoside hydrolase
HV033_RS06780	ENOG4105CDA	abc transporter atp-binding protein
HV033_RS06785	ENOG4105DRP	amino acid AbC transporter
HV033_RS06790	ENOG4105EAD	ABC transporter
HV033_RS06795	ENOG4107RP9	extracellular solute-binding protein, family 3
HV033_RS06800	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HV033_RS06805	ENOG4108JU5	Magnesium and cobalt efflux protein
HV033_RS06810	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HV033_RS06815	ENOG4105C9A	Phoh family
HV033_RS06820	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HV033_RS06825	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HV033_RS06865	ENOG4105CAQ	asparagine synthetase
HV033_RS06870	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HV033_RS06875	ENOG4105E2R	ROK family
HV033_RS06880	ENOG4105CE4	GlcNAc 6-P deacetylase
HV033_RS06890	ENOG4105CI1	PTS System
HV033_RS06895	ENOG4105CX6	glutaminyL-tRNA synthetase
HV033_RS06905	ENOG4105GX6	(LipO)protein
HV033_RS06910	ENOG41090R7	Ferric uptake
HV033_RS06920	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HV033_RS06925	ENOG4105NNH	LexA regulated protein
HV033_RS06930	ENOG4105EV9	Alpha Beta Hydrolase
HV033_RS06935	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HV033_RS06940	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HV033_RS06945	ENOG4105D5Q	Arginine ornithine antiporter
HV033_RS06950	ENOG4105CXN	decarboxylase
HV033_RS06960	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HV033_RS06965	ENOG4105C08	Histidine kinase
HV033_RS06970	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HV033_RS06975	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HV033_RS06980	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HV033_RS06990	ENOG4105XIQ	Protein of unknown function (DUF2517)
HV033_RS06995	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HV033_RS07000	ENOG4107QNR	UPF0135 protein
HV033_RS07005	ENOG4105P4J	Allophanate hydrolase, subunit 1
HV033_RS07010	ENOG4107R7A	Allophanate hydrolase subunit 2
HV033_RS07015	ENOG4105E7W	lamb ycsf family protein
HV033_RS07020	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
HV033_RS07025	ENOG4105BZN	citrate synthase
HV033_RS07030	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HV033_RS07035	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HV033_RS07040	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HV033_RS07045	ENOG4105E33	succinate dehydrogenase
HV033_RS07050	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HV033_RS07055	ENOG4105C7S	Dehydrogenase
HV033_RS07060	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HV033_RS07065	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HV033_RS07070	ENOG4105FDP	GntR family transcriptional regulator
HV033_RS07075	ENOG4105DM4	PTS System
HV033_RS07080	ENOG4105C8I	hydrolase, family 38
HV033_RS07085	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HV033_RS07090	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HV033_RS07100	ENOG4105KJB	cyd operon protein YbgE
HV033_RS07105	ENOG4107YD3	Thioesterase
HV033_RS07110	ENOG4105E02	MotA TolQ exbB proton channel
HV033_RS07120	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HV033_RS07125	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HV033_RS07130	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HV033_RS07135	ENOG4105UFD	tol-pal system protein YbgF
HV033_RS07170	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HV033_RS07175	ENOG4105PGM	cation diffusion facilitator family transporter
HV033_RS07180	ENOG4105JND	homeobox protein
HV033_RS07185	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HV033_RS07190	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HV033_RS07195	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HV033_RS07200	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HV033_RS07205	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HV033_RS07210	ENOG4105CMR	udp-glucose 4-epimerase
HV033_RS07215	ENOG4105DKW	ABC transporter
HV033_RS07220	ENOG4105F4R	Transcriptional regulator mode
HV033_RS07230	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HV033_RS07235	ENOG4105E0C	molybdate abc transporter
HV033_RS07245	ENOG4108K4B	hydrolase
HV033_RS07250	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HV033_RS07255	ENOG4105NBR	Pectinesterase
HV033_RS07260	ENOG4105CI2	imidazolone-5-propionate hydrolase
HV033_RS07265	ENOG41088SP	formiminoglutamate hydrolase
HV033_RS07275	ENOG4105CGP	Urocanate hydratase
HV033_RS07280	ENOG4105C84	Histidine ammonia-lyase
HV033_RS07285	ENOG4108V1U	phospholipid-binding protein
HV033_RS07290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HV033_RS07295	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HV033_RS07300	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HV033_RS07305	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HV033_RS07325	ENOG4105CHW	UPF0052 protein
HV033_RS07335	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HV033_RS07340	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HV033_RS07345	ENOG4105M00	molybdopterin converting factor, subunit 1
HV033_RS07350	ENOG4108ZAF	Molybdopterin
HV033_RS07355	ENOG4105HFZ	Membrane
HV033_RS07360	ENOG4107UXM	Membrane
HV033_RS07365	ENOG4105DZQ	phospholipase D Transphosphatidylase
HV033_RS07370	ENOG4105X23	Endonuclease Exonuclease phosphatase
HV033_RS07375	ENOG4105I9U	inner membrane protein ybhQ
HV033_RS07380	ENOG4107QWP	ABC-2 type transporter
HV033_RS07385	ENOG4107QWP	ABC-2 type transporter
HV033_RS07390	ENOG4105CJ1	ABC, transporter
HV033_RS07395	ENOG4105D0S	secretion protein (HlyD
HV033_RS07400	ENOG4107MVR	Transcriptional regulator
HV033_RS07405	ENOG4105C1J	atp-dependent rna helicase
HV033_RS07410	ENOG4105DVT	helicase
HV033_RS07425	ENOG4105CW0	outer membrane usher protein
HV033_RS07430	ENOG4108VCD	Chaperone
HV033_RS07435	ENOG4105MX3	Fimbrial
HV033_RS07440	ENOG4108MTB	glycosyl transferase family
HV033_RS07445	ENOG4105VR4	UPF0379 protein ybiJ
HV033_RS07450	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HV033_RS07455	ENOG4105ZY9	UPF0379 protein ybiM
HV033_RS07460	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HV033_RS07465	ENOG4105D8X	mechanosensitive ion channel
HV033_RS07470	ENOG4105CDA	abc transporter atp-binding protein
HV033_RS07475	ENOG4105E5Q	amino acid AbC transporter
HV033_RS07480	ENOG4107R0W	ABC transporter
HV033_RS07485	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HV033_RS07495	ENOG4108T1M	outer membrane protein x
HV033_RS07500	ENOG4108I6E	Sulfatase
HV033_RS07510	ENOG4105KST	dependent repressor
HV033_RS07515	ENOG4105F4P	)-transporter
HV033_RS07520	ENOG4105CW7	secretion protein, HlyD family
HV033_RS07525	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS07535	ENOG4105CPC	Aldo Keto reductase
HV033_RS07540	ENOG4105CS2	ec 3.2.1.21
HV033_RS07545	ENOG4105CK1	PTS System
HV033_RS07550	ENOG4105FDP	GntR family transcriptional regulator
HV033_RS07555	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HV033_RS07560	ENOG4105C5H	ABC transporter
HV033_RS07570	ENOG4105DPW	Major facilitator superfamily MFS_1
HV033_RS07575	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS07580	ENOG41072TH	Protein of unknown function (DUF1479)
HV033_RS07585	ENOG4108HCJ	Hydrolase
HV033_RS07595	ENOG4105F1A	Pyruvate formate-lyase
HV033_RS07600	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HV033_RS07605	ENOG4105D06	uba thif-type nad fad binding protein
HV033_RS07610	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HV033_RS07615	ENOG4105D44	asparaginase
HV033_RS07620	ENOG4108JQ6	ABC transporter
HV033_RS07640	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HV033_RS07645	ENOG4105UFT	Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway
HV033_RS07650	ENOG4105D8V	Glucose sorbosone dehydrogenase
HV033_RS07655	ENOG4108TGY	Glutathione S-transferase
HV033_RS07660	ENOG4105DZ1	carboxypeptidase
HV033_RS07665	ENOG4107FB0	transcriptional regulator DeoR family
HV033_RS07670	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HV033_RS07680	ENOG4107QF7	multi-drug
HV033_RS07685	ENOG4108HCJ	Hydrolase
HV033_RS07690	ENOG4106UW1	Major Facilitator superfamily
HV033_RS07695	ENOG4108RFG	Tetr family transcriptional regulator
HV033_RS07710	ENOG4105KBH	arsR family transcriptional regulator
HV033_RS07730	ENOG4105GWF	inner membrane protein YbjM
HV033_RS07735	ENOG41090BQ	Glutaredoxin
HV033_RS07740	ENOG4108DBC	nitroreductase
HV033_RS07745	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HV033_RS07750	ENOG4108RMJ	sensory transduction regulator
HV033_RS07755	ENOG4107RUE	extracellular solute-binding protein family 1
HV033_RS07760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HV033_RS07765	ENOG4105F38	ABC transporter, permease
HV033_RS07770	ENOG4105D38	putrescine abc transporter
HV033_RS07775	ENOG4105RBQ	inner membrane protein ybjO
HV033_RS07780	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HV033_RS07785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HV033_RS07790	ENOG4105BZU	Histidine kinase
HV033_RS07795	ENOG4106TNF	Periplasmic binding protein
HV033_RS07800	ENOG4105DMR	ABC, transporter
HV033_RS07805	ENOG4105GBT	ABC transporter
HV033_RS07810	ENOG4106PMH	Extracellular solute-binding protein family 3
HV033_RS07815	ENOG4105E5Z	arginine transporter ATP-binding subunit
HV033_RS07820	ENOG41064MM	(LipO)protein
HV033_RS07825	ENOG4105K8R	UPF0145 protein
HV033_RS07830	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HV033_RS07835	ENOG4108PNB	DNA-binding transcriptional regulator
HV033_RS07850	ENOG4108XKW	General secretion pathway protein C
HV033_RS07855	ENOG4105GVR	general secretion pathway protein D
HV033_RS07860	ENOG4107QHF	type ii secretion system protein e
HV033_RS07865	ENOG4105D7Q	type ii secretion system
HV033_RS07870	ENOG4108VAU	general secretion pathway protein G
HV033_RS07880	ENOG4105X5Z	General secretion pathway protein I
HV033_RS07925	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HV033_RS07930	ENOG4105CGD	Nad-dependent epimerase dehydratase
HV033_RS07935	ENOG4105C5W	Aldolase
HV033_RS07940	ENOG4105C7K	acetolactate synthase
HV033_RS07945	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HV033_RS07950	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HV033_RS07955	ENOG4105DWU	Membrane
HV033_RS07960	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HV033_RS07965	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HV033_RS07970	ENOG4108MJ5	VirK protein
HV033_RS07975	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HV033_RS07985	ENOG4105VEQ	Cold shock protein
HV033_RS07990	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HV033_RS07995	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HV033_RS08010	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HV033_RS08015	ENOG4108JJ8	(ABC) transporter
HV033_RS08020	ENOG4108JJ9	ABC, transporter
HV033_RS08025	ENOG4105C3M	thioredoxin reductase
HV033_RS08030	ENOG4105EW9	transcriptional regulator AsnC family
HV033_RS08035	ENOG4105CNU	cell division protein FtsK
HV033_RS08040	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HV033_RS08045	ENOG4105D1H	recombination factor protein RarA
HV033_RS08050	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HV033_RS08055	ENOG4107QY8	reductase
HV033_RS08060	ENOG4105QAX	Iron-sulfur
HV033_RS08065	ENOG4107KGK	dmso reductase anchor subunit
HV033_RS08070	ENOG4108ISG	Major Facilitator
HV033_RS08080	ENOG4105F1A	Pyruvate formate-lyase
HV033_RS08085	ENOG4105C6N	Formate acetyltransferase
HV033_RS08090	ENOG4105TMB	Formate nitrite transporter
HV033_RS08095	ENOG4105DDY	UPF0142 protein ycaO
HV033_RS08100	ENOG4107VMU	Membrane
HV033_RS08105	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HV033_RS08110	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HV033_RS08115	ENOG4105CAT	Cytidine monophosphate kinase
HV033_RS08120	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HV033_RS08125	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HV033_RS08130	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HV033_RS08135	ENOG4105BZ1	(ABC) transporter
HV033_RS08140	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HV033_RS08145	ENOG4105T0Z	Conserved Protein
HV033_RS08150	ENOG4105W49	UPF0434 protein
HV033_RS08155	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HV033_RS08160	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
HV033_RS08165	ENOG4107S90	membrAne
HV033_RS08170	ENOG4106371	Methyltransferase
HV033_RS08175	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HV033_RS08180	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HV033_RS08185	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HV033_RS08190	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HV033_RS08195	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HV033_RS08200	ENOG4105C5X	domain protein
HV033_RS08205	ENOG4105CGF	Aromatic amino acid aminotransferase
HV033_RS08215	ENOG4105C5S	asparaginyl-tRNA synthetase
HV033_RS08220	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HV033_RS08225	ENOG4105CD8	aminopeptidase N
HV033_RS08235	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HV033_RS08240	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HV033_RS08245	ENOG4105GVF	(ABC) transporter
HV033_RS08250	ENOG4108UZX	fmn reductase
HV033_RS08255	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HV033_RS08260	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HV033_RS08265	ENOG4105QVC	MOSC domain-containing protein
HV033_RS08270	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HV033_RS08275	ENOG4105C5H	ABC transporter
HV033_RS08280	ENOG4105F1S	paraquat-inducible protein a
HV033_RS08285	ENOG4105DY2	Paraquat-inducible protein b
HV033_RS08290	ENOG4108Q2G	(LipO)protein
HV033_RS08295	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HV033_RS08305	ENOG4105DAN	ATP-dependent protease
HV033_RS08310	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HV033_RS08315	ENOG4105UYK	outer membrane protein a
HV033_RS08320	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
HV033_RS08325	ENOG4108RZ1	DNA transformation protein
HV033_RS08330	ENOG4105EM2	membrane
HV033_RS08335	ENOG410901E	Membrane
HV033_RS08340	ENOG41088T4	Helicase IV
HV033_RS08345	ENOG4108Z5K	methylglyoxal synthase
HV033_RS08350	ENOG4108Q67	UPF0319 protein
HV033_RS08355	ENOG4105K4P	CoA-binding domain protein
HV033_RS08360	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HV033_RS08365	ENOG4105DR4	Methyltransferase
HV033_RS08370	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HV033_RS08380	ENOG4108MN8	Membrane
HV033_RS08385	ENOG4107QSI	ABC, transporter
HV033_RS08400	ENOG4105EHG	Permease protein
HV033_RS08410	ENOG4105EGS	Mechanosensitive ion channel
HV033_RS08430	ENOG4105CJW	magnesium transporter
HV033_RS08435	ENOG4107T5V	SNARE associated Golgi
HV033_RS08440	ENOG4105D6F	Phosphatase
HV033_RS08445	ENOG4105XH3	
HV033_RS08450	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HV033_RS08455	ENOG4105XF5	Escherichia coli IMT2125 genomic chromosome, IMT2125
HV033_RS08465	ENOG4105C2W	permease
HV033_RS08470	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HV033_RS08475	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HV033_RS08480	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HV033_RS08485	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
HV033_RS08490	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HV033_RS08495	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HV033_RS08500	ENOG4108R86	Transcriptional regulator
HV033_RS08510	ENOG4105C26	Dehydrogenase
HV033_RS08515	ENOG4105CK7	Sodium proline symporter
HV033_RS08525	ENOG4105D9N	nucleoside
HV033_RS08535	ENOG410650H	(LipO)protein
HV033_RS08540	ENOG4105DBE	peroxidase
HV033_RS08545	ENOG4105D5M	phosphate starvation-inducible protein
HV033_RS08550	ENOG4105BZG	amino acid carrier protein
HV033_RS08560	ENOG4105CHJ	isochorismatase hydrolase
HV033_RS08565	ENOG4105EUB	pirin domain protein
HV033_RS08570	ENOG4105CC0	LysR family Transcriptional regulator
HV033_RS08585	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HV033_RS08590	ENOG4107SSZ	Phosphatase
HV033_RS08595	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HV033_RS08600	ENOG4108UQ5	membrane protein YcdZ
HV033_RS08605	ENOG4105P8Q	Curli production assembly transport component CsgG
HV033_RS08610	ENOG4108WYR	Curli production assembly transport component, CsgF
HV033_RS08615	ENOG4108XDW	curli assembly protein CsgE
HV033_RS08620	ENOG41086KC	Transcriptional regulator
HV033_RS08625	ENOG4108U0V	Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers
HV033_RS08630	ENOG4105G76	Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin
HV033_RS08635	ENOG4105RK8	Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity)
HV033_RS08640	ENOG41068SS	
HV033_RS08645	ENOG4108UVJ	appr-1-p processing domain protein
HV033_RS08660	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HV033_RS08665	ENOG4105NAC	(LipO)protein
HV033_RS08670	ENOG4108W47	Acidic protein msyB
HV033_RS08680	ENOG4105D1S	lipid A biosynthesis
HV033_RS08685	ENOG4105C72	UPF0176 protein
HV033_RS08690	ENOG4108YYC	ycei family
HV033_RS08695	ENOG4105DS1	cytochrome b561
HV033_RS08700	ENOG4106974	biofilm formation
HV033_RS08705	ENOG4105F76	Sarcosine oxidase
HV033_RS08710	ENOG4105PVA	Biofilm formation regulatory protein BssS
HV033_RS08715	ENOG4105MEA	DNA damage-inducible protein i
HV033_RS08720	ENOG4105EKE	dihydroorotase
HV033_RS08725	ENOG4105F3T	(LipO)protein
HV033_RS08730	ENOG4105EV4	Multidrug resistance protein mdtH
HV033_RS08735	ENOG4105D9U	N-acetyltransferase
HV033_RS08740	ENOG4108YXG	UPF0502 protein
HV033_RS08745	ENOG4105EP9	oxidoreductase
HV033_RS08750	ENOG4105CJR	Integral membrane protein (MviN
HV033_RS08755	ENOG4105QVD	Flagella synthesis protein FlgN
HV033_RS08760	ENOG4105M9M	anti-sigma28 factor FlgM
HV033_RS08765	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HV033_RS08770	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HV033_RS08775	ENOG4108ZC9	flagellar basal-body rod protein flgc
HV033_RS08780	ENOG4105W00	Flagellar hook capping protein
HV033_RS08785	ENOG4105BZE	flagellar hook protein, FlgE
HV033_RS08790	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HV033_RS08795	ENOG4105CGA	flagellar basal-body rod protein FlgG
HV033_RS08810	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HV033_RS08815	ENOG4105E1Q	flagellar hook-associated protein
HV033_RS08820	ENOG4105DTJ	flagellar hook-associated protein
HV033_RS08825	ENOG4105EQ0	Major Facilitator superfamily
HV033_RS08830	ENOG4105EJC	lysr family transcriptional regulator
HV033_RS08835	ENOG4107QQB	Ribonuclease E
HV033_RS08840	ENOG4105EI2	Pseudouridine synthase
HV033_RS08845	ENOG4108UHJ	MAF-like protein
HV033_RS08850	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HV033_RS08855	ENOG4105VGS	50s ribosomal protein l32
HV033_RS08860	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HV033_RS08865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HV033_RS08870	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HV033_RS08875	ENOG4105CHR	reductase
HV033_RS08880	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HV033_RS08885	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HV033_RS08890	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HV033_RS08895	ENOG4105HHA	aminodeoxychorismate lyase
HV033_RS08905	ENOG4107QRG	dna polymerase iii
HV033_RS08910	ENOG4105F8V	Hydrolase, tatD family
HV033_RS08915	ENOG4105CI1	PTS System
HV033_RS08920	ENOG4105CNM	Receptor
HV033_RS08925	ENOG4105K59	histidine triad (HIT) protein
HV033_RS08930	ENOG41090DQ	Lipoprotein
HV033_RS08935	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
HV033_RS08950	ENOG4105D0Y	UPF0227 protein
HV033_RS08955	ENOG4105CEP	NADH dehydrogenase
HV033_RS08960	ENOG4107MBR	17 kDa surface antigen
HV033_RS08965	ENOG4108IND	Tetr family transcriptional regulator
HV033_RS08970	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
HV033_RS08975	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HV033_RS08980	ENOG4108JA2	transcriptioN-repair coupling factor
HV033_RS08985	ENOG4105IQC	Inner membrane protein YcfT
HV033_RS08990	ENOG4105D60	lipoprotein releasing system transmembrane protein
HV033_RS08995	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HV033_RS09000	ENOG4105D60	lipoprotein releasing system transmembrane protein
HV033_RS09005	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HV033_RS09010	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HV033_RS09015	ENOG4108HM4	ABC transporter
HV033_RS09020	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
HV033_RS09040	ENOG4108UK5	Transposase
HV033_RS09045	ENOG4105EZE	Cupin 4 family protein
HV033_RS09050	ENOG4105IFJ	Histidine kinase
HV033_RS09055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HV033_RS09065	ENOG4107QTF	adenylosuccinate lyase
HV033_RS09070	ENOG41075W9	High frequency lysogenization protein HflD homolog
HV033_RS09085	ENOG4108R99	pseudouridine synthase
HV033_RS09090	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HV033_RS09095	ENOG4105N0E	Protein of unknown function (DUF2543)
HV033_RS09100	ENOG41066DG	(EAL) domain protein
HV033_RS09110	ENOG4105Y3U	Transglycosylase-associated protein
HV033_RS09120	ENOG4106G4W	
HV033_RS09125	ENOG410620I	Diguanylate cyclase
HV033_RS09130	ENOG4105UCG	Domain of unknown function (DUF333)
HV033_RS09140	ENOG4105K78	MarR family Transcriptional regulator
HV033_RS09145	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HV033_RS09150	ENOG4105DJ2	Major Facilitator Superfamily
HV033_RS09155	ENOG4105R1U	AraC Family Transcriptional Regulator
HV033_RS09160	ENOG4108VMM	UPF0756 membrane protein
HV033_RS09170	ENOG4105CT4	transporter
HV033_RS09175	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
HV033_RS09200	ENOG4105CKK	Glycosyl transferase, family 2
HV033_RS09210	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
HV033_RS09215	ENOG4105EKQ	RNA-directed DNA polymerase
HV033_RS09230	ENOG4106AKX	UPF0229 protein
HV033_RS09235	ENOG4105CYN	Serine protein kinase
HV033_RS09240	ENOG4105GNX	MltA-interacting MipA family protein
HV033_RS09245	ENOG4105DSB	aldose 1-epimerase
HV033_RS09250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HV033_RS09260	ENOG4105VUT	cytoplasmic protein
HV033_RS09270	ENOG4108RWI	nicotinamidase
HV033_RS09275	ENOG4105HDK	L-asparaginase
HV033_RS09280	ENOG4105D07	Signal peptide peptidase, SppA
HV033_RS09285	ENOG41069NU	Nitroreductase
HV033_RS09290	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HV033_RS09295	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HV033_RS09300	ENOG4105D82	Glutamate dehydrogenase
HV033_RS09305	ENOG4105MTM	Protein of unknown function (DUF1496)
HV033_RS09310	ENOG4105M6F	mutator MutT protein
HV033_RS09315	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HV033_RS09320	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
HV033_RS09325	ENOG4107RM6	sulfurtransferase
HV033_RS09330	ENOG4108VGW	abc transporter atp-binding protein
HV033_RS09335	ENOG4105CXZ	ABC transporter, permease
HV033_RS09340	ENOG4105VNH	ABC transporter solute-binding protein
HV033_RS09350	ENOG4105CGK	Exodeoxyribonuclease III
HV033_RS09355	ENOG4105C8Y	Acetylornithine aminotransferase
HV033_RS09360	ENOG4105F4X	arginine
HV033_RS09365	ENOG4105C26	Dehydrogenase
HV033_RS09370	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HV033_RS09380	ENOG4108SPG	Periplasmic Protein
HV033_RS09385	ENOG41090B9	response to stress
HV033_RS09390	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
HV033_RS09395	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HV033_RS09400	ENOG4105KKI	DNA-binding transcriptional activator OsmE
HV033_RS09405	ENOG4105VZJ	PTS System
HV033_RS09410	ENOG4105CK1	PTS System
HV033_RS09415	ENOG4105VCP	PTS System
HV033_RS09420	ENOG4105EZV	Transcriptional regulator
HV033_RS09425	ENOG4105F8D	glycoside hydrolase family 4
HV033_RS09430	ENOG410901P	UPF0249 protein
HV033_RS09435	ENOG4105CH6	catalase
HV033_RS09445	ENOG4108ETY	sodium dicarboxylate symporter
HV033_RS09450	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HV033_RS09455	ENOG4105CHR	reductase
HV033_RS09460	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HV033_RS09465	ENOG4107PN8	YfeABCD locus regulator
HV033_RS09475	ENOG4105P10	Uncharacterized protein ydiZ
HV033_RS09480	ENOG4105DE4	1-phosphofructokinase
HV033_RS09490	ENOG4108NE3	Salt-induced outer membrane protein
HV033_RS09495	ENOG4105VR4	UPF0379 protein ybiJ
HV033_RS09515	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HV033_RS09520	ENOG41082NX	50s ribosomal protein l35
HV033_RS09535	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HV033_RS09540	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HV033_RS09545	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HV033_RS09555	ENOG4108V06	Glutathione peroxidase
HV033_RS09560	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HV033_RS09565	ENOG4108QBX	(LipO)protein
HV033_RS09570	ENOG4108TC0	Diguanylate phosphodiesterase
HV033_RS09575	ENOG4105CNG	UPF0061 protein
HV033_RS09580	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HV033_RS09585	ENOG4105EHG	Permease protein
HV033_RS09590	ENOG4107R4I	Periplasmic binding protein
HV033_RS09595	ENOG4106QJH	hemin transport protein
HV033_RS09600	ENOG4107ENK	receptor
HV033_RS09610	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HV033_RS09615	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HV033_RS09620	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HV033_RS09625	ENOG4105CT4	transporter
HV033_RS09630	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HV033_RS09645	ENOG4105IPI	Membrane
HV033_RS09650	ENOG4105CQB	FAD linked oxidase domain protein
HV033_RS09655	ENOG4105KA0	thioesterase Superfamily protein
HV033_RS09660	ENOG410671Z	uncharacterized protein ydiH
HV033_RS09665	ENOG4108PNB	DNA-binding transcriptional regulator
HV033_RS09670	ENOG4108PNB	DNA-binding transcriptional regulator
HV033_RS09680	ENOG4108VCD	Chaperone
HV033_RS09685	ENOG4105CW0	outer membrane usher protein
HV033_RS09705	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HV033_RS09720	ENOG4105WKE	Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component
HV033_RS09725	ENOG4105BZU	Histidine kinase
HV033_RS09730	ENOG4108XDN	Transcriptional regulator
HV033_RS09750	ENOG4108Z4V	iron-sulfur cluster assembly
HV033_RS09755	ENOG4105DIW	FeS assembly protein SUFB
HV033_RS09760	ENOG4105C3K	feS assembly ATPase SufC
HV033_RS09765	ENOG4105JRK	feS assembly protein SufD
HV033_RS09770	ENOG4105C9B	Cysteine desulfurase
HV033_RS09775	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HV033_RS09780	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HV033_RS09790	ENOG4105CA9	Pyruvate kinase
HV033_RS09795	ENOG4105C28	cystathionine
HV033_RS09810	ENOG4108UMI	ABC transporter, permease
HV033_RS09815	ENOG4105D01	(LipO)protein
HV033_RS09820	ENOG4105RFR	Protein of unknown function (DUF2767)
HV033_RS09845	ENOG4107B2H	carbonic anhydrase
HV033_RS09850	ENOG4108KTU	conserved protein with FAD NAD(P)-binding domain
HV033_RS09865	ENOG4107QI1	Mate efflux family protein
HV033_RS09870	ENOG4108R6K	riboflavin synthase, subunit alpha
HV033_RS09875	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HV033_RS09880	ENOG4105CZQ	inner membrane transport protein YdhC
HV033_RS09885	ENOG4105F52	Transcriptional regulator
HV033_RS09890	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS09900	ENOG4105F27	Major Facilitator
HV033_RS09905	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HV033_RS09910	ENOG4105K4H	Nlp p60 protein
HV033_RS09915	ENOG4105M2J	Glutaredoxin
HV033_RS09920	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HV033_RS09925	ENOG4108UYE	Lactoylglutathione lyase
HV033_RS09930	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HV033_RS09935	ENOG4108WUH	Transcriptional regulator, TetR family
HV033_RS09940	ENOG4105DIJ	Phosphoethanolamine transferase
HV033_RS09945	ENOG4105XZD	Fe-S protein
HV033_RS09950	ENOG4107RGM	aldo keto reductase
HV033_RS09955	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HV033_RS09960	ENOG4105DSW	Fusaric acid resistance protein
HV033_RS09965	ENOG4105Y49	secretion protein, HlyD family
HV033_RS09980	ENOG4105BZU	Histidine kinase
HV033_RS09985	ENOG4108XTF	Outer Membrane Lipoprotein
HV033_RS09990	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HV033_RS09995	ENOG410642K	Lysozyme inhibitor
HV033_RS10000	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HV033_RS10005	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HV033_RS10010	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HV033_RS10015	ENOG4108K3A	Glutathione S-transferase
HV033_RS10020	ENOG4105DUX	Transporter
HV033_RS10025	ENOG4105CSM	endonuclease III
HV033_RS10035	ENOG4108UQQ	Electron transport complex
HV033_RS10040	ENOG4105D6A	Electron transport complex
HV033_RS10055	ENOG4105DGN	Electron transport complex
HV033_RS10060	ENOG4105M9B	inner membrane protein ydgK
HV033_RS10070	ENOG4106C6R	beta-lactam resistance protein
HV033_RS10155	ENOG4105KPY	Small multidrug resistance protein
HV033_RS10165	ENOG4106NZI	LysR family Transcriptional regulator
HV033_RS10200	ENOG4105CY3	ABC transporter, permease
HV033_RS10205	ENOG4105DHJ	ABC, transporter
HV033_RS10305	ENOG4108YGG	dna repair protein
HV033_RS10310	ENOG4105DFS	Conserved Protein
HV033_RS10320	ENOG4105D9R	oxidoreductase
HV033_RS10325	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HV033_RS10330	ENOG4105C87	Aminotransferase class I and II
HV033_RS10335	ENOG4105CI1	PTS System
HV033_RS10340	ENOG4107P2S	Transcriptional regulator
HV033_RS10345	ENOG4106J39	exported protein
HV033_RS10350	ENOG4105EIP	mannose-6-phosphate isomerase
HV033_RS10355	ENOG4107GFK	fumarate
HV033_RS10360	ENOG4105C9Q	fumarate hydratase class II
HV033_RS10365	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HV033_RS10370	ENOG4105JJR	Histidine kinase
HV033_RS10375	ENOG41066T8	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation (By similarity)
HV033_RS10380	ENOG4107EXC	regulatoR
HV033_RS10385	ENOG4105RA2	Membrane
HV033_RS10390	ENOG410642E	Short chain dehydrogenase
HV033_RS10395	ENOG4105D5Q	Arginine ornithine antiporter
HV033_RS10400	ENOG4105C5D	exported protein
HV033_RS10405	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HV033_RS10410	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HV033_RS10415	ENOG4105D64	Mechanosensitive ion channel
HV033_RS10420	ENOG4105Q9Y	Universal stress protein
HV033_RS10425	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HV033_RS10430	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HV033_RS10435	ENOG4105CFC	Transporter
HV033_RS10440	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HV033_RS10450	ENOG4106KR7	LysR family Transcriptional regulator
HV033_RS10455	ENOG4108DG9	Smr protein MutS2
HV033_RS10460	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS10465	ENOG4107S5I	aldo keto reductase
HV033_RS10475	ENOG4105DZG	Dehydrogenase
HV033_RS10480	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
HV033_RS10500	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
HV033_RS10510	ENOG4108IGT	Dipeptidase
HV033_RS10520	ENOG4105N1F	Hnh endonuclease
HV033_RS10525	ENOG4108M8W	Monooxygenase
HV033_RS10535	ENOG4105DSF	transport protein
HV033_RS10540	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HV033_RS10545	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HV033_RS10550	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
HV033_RS10565	ENOG4105CTD	carboxy-peptidase
HV033_RS10570	ENOG4105D94	Major Facilitator Superfamily
HV033_RS10575	ENOG4106NZI	LysR family Transcriptional regulator
HV033_RS10580	ENOG4105DAG	ROK family
HV033_RS10585	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HV033_RS10590	ENOG4105CMQ	Chloride channel
HV033_RS10595	ENOG4108IJ8	ABC transporter
HV033_RS10600	ENOG4105E90	ABC transporter
HV033_RS10605	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HV033_RS10610	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
HV033_RS10670	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS10675	ENOG4108UY2	Chloramphenicol acetyltransferase
HV033_RS10680	ENOG4105X2V	dna damage-inducible protein
HV033_RS10685	ENOG4108NEM	leader-binding protein dmsD
HV033_RS10690	ENOG4107KGK	dmso reductase anchor subunit
HV033_RS10695	ENOG4105QAX	Iron-sulfur
HV033_RS10700	ENOG4107QY8	reductase
HV033_RS10705	ENOG4105KBG	Protein of unknown function (DUF1161)
HV033_RS10725	ENOG4105M5Q	UPF0482 protein
HV033_RS10730	ENOG4105KK4	UPF0060 membrane protein
HV033_RS10735	ENOG4105CXK	mandelate racemase muconate lactonizing
HV033_RS10740	ENOG4105CPQ	Dehydrogenase
HV033_RS10750	ENOG4105DEI	Mannitol dehydrogenase
HV033_RS10755	ENOG41061EV	selenium-binding protein YdfZ
HV033_RS10760	ENOG4108U51	Universal stress protein
HV033_RS10765	ENOG4107XBN	GntR Family Transcriptional Regulator
HV033_RS10770	ENOG4105EMU	Dehydrogenase
HV033_RS10775	ENOG4105DGW	oligopeptidase A
HV033_RS10780	ENOG4106IAW	
HV033_RS10785	ENOG4105VEQ	Cold shock protein
HV033_RS10790	ENOG4108RAV	Conserved protein
HV033_RS10795	ENOG4105Y50	Virulence Protein
HV033_RS10800	ENOG4105EKQ	RNA-directed DNA polymerase
HV033_RS10805	ENOG4105KT5	UmuD protein
HV033_RS10810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HV033_RS10830	ENOG4105D7N	magnesium and cobalt transport protein CorA
HV033_RS10845	ENOG4105DZG	Dehydrogenase
HV033_RS10860	ENOG4106H71	Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation
HV033_RS10870	ENOG4105C5I	Dehydrogenase
HV033_RS10875	ENOG4107H52	Dicarboxylate transport
HV033_RS10880	ENOG410689M	(LipO)protein
HV033_RS10885	ENOG4105WXT	Conserved Protein
HV033_RS10890	ENOG4108WFR	AraC Family Transcriptional Regulator
HV033_RS10895	ENOG4105C26	Dehydrogenase
HV033_RS10905	ENOG4105EUZ	Beta-lactamase domain protein
HV033_RS10910	ENOG4105F11	amine oxidase
HV033_RS10930	ENOG4105DXM	phenylacetic acid degradation protein
HV033_RS10935	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HV033_RS10940	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HV033_RS10945	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HV033_RS10950	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HV033_RS10955	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HV033_RS10960	ENOG4105E39	Enoyl-CoA hydratase
HV033_RS10965	ENOG4108UKI	Enoyl-CoA hydratase
HV033_RS10970	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HV033_RS10975	ENOG4108ZJI	phenylacetic acid degradation protein
HV033_RS10980	ENOG4105CHU	acetyl-coa acetyltransferase
HV033_RS10985	ENOG4105DZS	Phenylacetate-CoA ligase
HV033_RS10990	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HV033_RS10995	ENOG4108Z0R	Transferase
HV033_RS11000	ENOG4105C94	Transporter
HV033_RS11010	ENOG4105EUZ	Beta-lactamase domain protein
HV033_RS11030	ENOG4107FW0	short-chain dehydrogenase reductase
HV033_RS11045	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HV033_RS11080	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HV033_RS11090	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HV033_RS11095	ENOG4105D3G	Pseudouridine synthase
HV033_RS11100	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HV033_RS11105	ENOG4105CQ7	ATP-dependent helicase
HV033_RS11115	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HV033_RS11130	ENOG4105CSH	Transporter
HV033_RS11135	ENOG4107DB1	DUF218 domain
HV033_RS11140	ENOG4105C26	Dehydrogenase
HV033_RS11145	ENOG4105CPW	cytochrome b561
HV033_RS11150	ENOG4105D9R	oxidoreductase
HV033_RS11155	ENOG4105E98	transcriptional regulator DeoR family
HV033_RS11170	ENOG4108JJA	ABC, transporter
HV033_RS11175	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HV033_RS11200	ENOG4105WKE	Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component
HV033_RS11225	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS11230	ENOG4105DDW	LysR family Transcriptional regulator
HV033_RS11235	ENOG4105E32	cytoplasmic protein
HV033_RS11240	ENOG4105EBR	Carboxylesterase
HV033_RS11300	ENOG4105E89	ABC transporter
HV033_RS11305	ENOG4105DJ9	glucan biosynthesis protein
HV033_RS11310	ENOG4108Z9I	-acetyltransferase
HV033_RS11315	ENOG4107WE3	acetyltransferase YdcK
HV033_RS11320	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
HV033_RS11325	ENOG41088CC	tellurite resistance protein tehB
HV033_RS11330	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HV033_RS11335	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV033_RS11340	ENOG4108KKZ	(LipO)protein
HV033_RS11345	ENOG4108IPJ	Membrane
HV033_RS11355	ENOG4105DKK	Benzoate
HV033_RS11360	ENOG4108JCI	Transcriptional regulator
HV033_RS11365	ENOG4105CFP	Peptidase U32
HV033_RS11370	ENOG4105RR0	Protein of unknown function (DUF2554)
HV033_RS11380	ENOG4105ECQ	AraC Family Transcriptional Regulator
HV033_RS11400	ENOG4105C32	Amino acid ABC transporter (Permease)
HV033_RS11405	ENOG4105CNN	ABC, transporter
HV033_RS11410	ENOG4105C2J	ABC transporter
HV033_RS11415	ENOG4108IV0	ABC, transporter
HV033_RS11420	ENOG4108MEK	Metal-binding protein YodA
HV033_RS11425	ENOG4105E5W	Transporter
HV033_RS11430	ENOG4108594	Permease of the drug metabolite transporter
HV033_RS11435	ENOG4106DNR	multiple antibiotic resistance protein
HV033_RS11440	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
HV033_RS11445	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HV033_RS11450	ENOG41082NP	Multiple antibiotic resistance
HV033_RS11455	ENOG4105F27	Major Facilitator
HV033_RS11460	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HV033_RS11465	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HV033_RS11475	ENOG4105EGI	Transcriptional regulator
HV033_RS11480	ENOG4105C26	Dehydrogenase
HV033_RS11485	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS11490	ENOG4105CSV	Glutaminase
HV033_RS11495	ENOG4105M0C	cytoplasmic protein
HV033_RS11500	ENOG4105BZU	Histidine kinase
HV033_RS11510	ENOG4107QZW	Altronate oxidoreductase
HV033_RS11515	ENOG4105FFC	UPF0187 protein
HV033_RS11535	ENOG4108MBX	Secretion Protein
HV033_RS11550	ENOG4105CPT	Alpha beta hydrolase
HV033_RS11560	ENOG4105E0F	Histidine kinase
HV033_RS11575	ENOG4107VIJ	nudix hydrolase
HV033_RS11580	ENOG4105E98	transcriptional regulator DeoR family
HV033_RS11590	ENOG4105CHR	reductase
HV033_RS11595	ENOG4105ENX	hydrolase
HV033_RS11600	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS11605	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS11630	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS11650	ENOG4105CW0	outer membrane usher protein
HV033_RS11655	ENOG4108VCD	Chaperone
HV033_RS11670	ENOG4108VCD	Chaperone
HV033_RS11675	ENOG4105CW0	outer membrane usher protein
HV033_RS11715	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HV033_RS11725	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HV033_RS11740	ENOG4107RSM	transcriptional regulator
HV033_RS11750	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HV033_RS11755	ENOG4105F32	YngK protein
HV033_RS11760	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HV033_RS11775	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS11780	ENOG4105WBN	Transcriptional regulator (LacI family
HV033_RS11795	ENOG4108M0B	Sucrose porin
HV033_RS11800	ENOG4105D7K	pfkb domain protein
HV033_RS11805	ENOG4105BZU	Histidine kinase
HV033_RS11815	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
HV033_RS11820	ENOG4108UQS	dipeptidase
HV033_RS11825	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV033_RS11830	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HV033_RS11835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV033_RS11840	ENOG4105C3U	ABC transporter
HV033_RS11845	ENOG4107H6U	ABC transporter
HV033_RS11850	ENOG4108Z9K	Osmotically inducible protein
HV033_RS11855	ENOG4105EXG	Transcriptional regulator
HV033_RS11870	ENOG4105TPS	biofilm-dependent modulation protein
HV033_RS11875	ENOG4107AV5	Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein
HV033_RS11880	ENOG4107R1I	NAD-dependent malic enzyme
HV033_RS11895	ENOG4105C5H	ABC transporter
HV033_RS11900	ENOG4105DQ4	alcohol dehydrogenase
HV033_RS11915	ENOG4105F27	Major Facilitator
HV033_RS11930	ENOG4108MG3	formate dehydrogenase
HV033_RS11935	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HV033_RS11945	ENOG4105RPH	Inner membrane protein YddG
HV033_RS11950	ENOG4105FCK	Membrane
HV033_RS11965	ENOG4107QND	Nitrite extrusion protein
HV033_RS11970	ENOG4105CRU	nitrate reductase, alpha subunit
HV033_RS11975	ENOG4108IUE	nitrate reductase beta subunit
HV033_RS11980	ENOG4108NZN	Respiratory nitrate reductase 2 delta chain
HV033_RS11985	ENOG4105D0D	Nitrate reductase 2, gamma subunit
HV033_RS11990	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
HV033_RS11995	ENOG4108MEJ	flavin reductase domain protein
HV033_RS12010	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HV033_RS12015	ENOG4105YVS	arsR family transcriptional regulator
HV033_RS12020	ENOG4105W8I	Transcriptional regulator
HV033_RS12025	ENOG4105KD7	acetyltransferase
HV033_RS12035	ENOG4105D1S	lipid A biosynthesis
HV033_RS12040	ENOG4105KZK	Tautomerase pptA
HV033_RS12045	ENOG4108N27	Glutathione S-transferase
HV033_RS12050	ENOG4105EAB	amino acid AbC transporter
HV033_RS12055	ENOG4105CDA	abc transporter atp-binding protein
HV033_RS12070	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HV033_RS12085	ENOG4105DEN	Luciferase family
HV033_RS12095	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS12100	ENOG4105C85	amino acid
HV033_RS12105	ENOG4108NS2	receptor
HV033_RS12110	ENOG4105CHB	tonB-dependent Receptor
HV033_RS12115	ENOG4108WYP	Transcriptional regulator
HV033_RS12120	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HV033_RS12130	ENOG4108Z7F	N-acetyltransferase
HV033_RS12135	ENOG4108T9Y	Inner membrane protein ydcZ
HV033_RS12140	ENOG4105R71	cytoplasmic protein
HV033_RS12145	ENOG4105DEF	Extracellular solute-binding protein, family 5
HV033_RS12185	ENOG4105D13	transposase
HV033_RS12210	ENOG410654E	Membrane
HV033_RS12215	ENOG4108YS1	cytoplasmic protein
HV033_RS12220	ENOG4108YS1	cytoplasmic protein
HV033_RS12225	ENOG4105YP6	Domain of unknown function (DUF1869)
HV033_RS12230	ENOG4105C26	Dehydrogenase
HV033_RS12235	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HV033_RS12245	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HV033_RS12250	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HV033_RS12260	ENOG41090X5	Heat shock protein hslJ
HV033_RS12265	ENOG4105IKK	cytoplasmic protein
HV033_RS12270	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HV033_RS12275	ENOG4105FCK	Membrane
HV033_RS12290	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HV033_RS12295	ENOG4105C1J	atp-dependent rna helicase
HV033_RS12310	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS12370	ENOG4107QSI	ABC, transporter
HV033_RS12375	ENOG4105KXI	murein peptide amidase A
HV033_RS12380	ENOG4107S8C	mandelate racemase muconate lactonizing
HV033_RS12385	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HV033_RS12390	ENOG4108JU8	Transcriptional regulator
HV033_RS12395	ENOG4106K28	UPF0283 membrane protein
HV033_RS12400	ENOG4105CM6	amino acid regulated cytosolic protein
HV033_RS12405	ENOG4105FKQ	transcriptional regulator
HV033_RS12410	ENOG4107EFV	Outer membrane protein G
HV033_RS12415	ENOG4108IJ9	(ABC) transporter
HV033_RS12420	ENOG4107URF	beta-phospho-glucomutase
HV033_RS12425	ENOG4105C71	hydrolase family 65, central catalytic
HV033_RS12430	ENOG4105CK5	oxidoreductase
HV033_RS12435	ENOG4107TYA	transient receptor potential locus
HV033_RS12440	ENOG4107RRD	Dehydrogenase
HV033_RS12445	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HV033_RS12450	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
HV033_RS12455	ENOG4105WEM	extracellular solute-binding protein
HV033_RS12460	ENOG4107QW3	Sucrose phosphorylase
HV033_RS12465	ENOG4105NNG	Peripheral inner membrane phage-shock protein
HV033_RS12470	ENOG4105FM1	phage shock protein C
HV033_RS12475	ENOG4105YYT	phage shock protein B
HV033_RS12480	ENOG41087YS	Phage shock protein A
HV033_RS12485	ENOG4105E51	psp operon transcriptional activator
HV033_RS12490	ENOG4108J59	Extracellular solute-binding protein, family 5
HV033_RS12495	ENOG4108EKA	peptide transport system, permease
HV033_RS12500	ENOG4108EU3	peptide transport system, permease
HV033_RS12505	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HV033_RS12510	ENOG4108JQ2	peptide transport system atp-binding protein
HV033_RS12515	ENOG4108Q5F	Tetr family transcriptional regulator
HV033_RS12520	ENOG4108UQ8	endoribonuclease L-psp
HV033_RS12525	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HV033_RS12530	ENOG4105Q4T	oxidoreductase
HV033_RS12535	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HV033_RS12540	ENOG4105BZU	Histidine kinase
HV033_RS12545	ENOG4105E39	Enoyl-CoA hydratase
HV033_RS12550	ENOG410643D	UPF0509 protein
HV033_RS12555	ENOG4105N2W	Transcriptional regulator
HV033_RS12560	ENOG41061RM	osmotically inducible lipoprotein
HV033_RS12565	ENOG4108ZJT	translation initiation factor, Sui1
HV033_RS12570	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HV033_RS12575	ENOG4105CFV	Tetratricopeptide repeat protein
HV033_RS12580	ENOG4105Q4A	inner membrane protein yciS
HV033_RS12585	ENOG4105EYK	Phosphatidylglycerophosphatase B
HV033_RS12590	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HV033_RS12595	ENOG4107QM5	aconitate hydratase
HV033_RS12610	ENOG4107R11	Transcriptional regulator
HV033_RS12615	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HV033_RS12620	ENOG4105RKX	Protein of unknown function (DUF2498)
HV033_RS12625	ENOG4105ERU	peptidase
HV033_RS12630	ENOG4105UBK	short-chain dehydrogenase reductase
HV033_RS12635	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HV033_RS12640	ENOG4105FE9	pseudouridine synthase
HV033_RS12645	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HV033_RS12650	ENOG4105DB7	PHP domain protein
HV033_RS12660	ENOG4105CRQ	synthase (Component I)
HV033_RS12665	ENOG4108EFP	Anthranilate synthase component II
HV033_RS12670	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HV033_RS12675	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HV033_RS12680	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HV033_RS12685	ENOG41066VF	YeeE YedE family protein
HV033_RS12695	ENOG4105EIF	outer membrane protein W
HV033_RS12700	ENOG4105PI0	Ferredoxin
HV033_RS12705	ENOG4108S3I	UPF0259 membrane protein
HV033_RS12710	ENOG4107835	probably involved in intracellular septation (By similarity)
HV033_RS12715	ENOG4107RNH	Outer membrane receptor FepA
HV033_RS12720	ENOG4105NAU	thioesterase Superfamily protein
HV033_RS12725	ENOG410822N	TonB family
HV033_RS12730	ENOG4105K9H	YciI-like protein
HV033_RS12750	ENOG4108NIW	Leucine export protein LeuE
HV033_RS12765	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HV033_RS12770	ENOG4108W5H	UPF0263 protein
HV033_RS12775	ENOG4105EYW	Ion transport protein
HV033_RS12780	ENOG4108JQ7	(ABC) transporter
HV033_RS12785	ENOG4105C3U	ABC transporter
HV033_RS12790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HV033_RS12795	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HV033_RS12800	ENOG4107QSI	ABC, transporter
HV033_RS12805	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HV033_RS12810	ENOG4105C0A	alcohol dehydrogenase
HV033_RS12815	ENOG4107104	thymidine kinase
HV033_RS12825	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HV033_RS12830	ENOG4105I93	response regulator
HV033_RS12835	ENOG4105D78	K07001 NTE family protein
HV033_RS12840	ENOG4105K5B	UPF0225 protein
HV033_RS12845	ENOG4105CIY	formyltetrahydrofolate deformylase
HV033_RS12860	ENOG41076YT	nitrate reductase, gamma subunit
HV033_RS12865	ENOG4105R3A	Nitrate reductase
HV033_RS12870	ENOG4108IUE	nitrate reductase beta subunit
HV033_RS12875	ENOG4105CRU	nitrate reductase, alpha subunit
HV033_RS12880	ENOG4105DQQ	Major facilitator superfamily MFS_1
HV033_RS12885	ENOG4105BZU	Histidine kinase
HV033_RS12890	ENOG4105WH1	Two component transcriptional regulator luxr family
HV033_RS12895	ENOG4105ID0	Putative invasin
HV033_RS12905	ENOG4107QZF	nitrite reductase NADPH large subunit
HV033_RS12910	ENOG4105D7T	ABC transporter
HV033_RS12930	ENOG41090EX	DsrE family
HV033_RS12935	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS12945	ENOG4108NH8	Cation transport protein
HV033_RS12950	ENOG4105WS7	Cation transport regulator
HV033_RS12955	ENOG4105EWV	Sodium calcium exchanger membrane region
HV033_RS12960	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HV033_RS12965	ENOG41063JG	Transcriptional regulator
HV033_RS12970	ENOG4108YY7	Invasion gene expression up-regulator SirB
HV033_RS12975	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HV033_RS12980	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HV033_RS12985	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HV033_RS12990	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HV033_RS12995	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HV033_RS13000	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HV033_RS13005	ENOG4105CHH	sulfate transporter
HV033_RS13015	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HV033_RS13020	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HV033_RS13025	ENOG4105C3G	gtp-binding protein
HV033_RS13040	ENOG4105CNA	YD repeat protein
HV033_RS13075	ENOG4105D9P	serine threonine protein kinase
HV033_RS13080	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HV033_RS13140	ENOG4108WC9	type VI secretion system effector, hcp1 family
HV033_RS13185	ENOG4106VK6	Flagellar motor protein
HV033_RS13215	ENOG4105E53	ec 3.2.1.28
HV033_RS13220	ENOG4105E0K	tonB-dependent siderophore receptor
HV033_RS13225	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
HV033_RS13230	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HV033_RS13235	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HV033_RS13240	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HV033_RS13245	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HV033_RS13250	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HV033_RS13255	ENOG4105ED1	spovr family
HV033_RS13265	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HV033_RS13270	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HV033_RS13275	ENOG4108ZZ3	UPF0260 protein
HV033_RS13280	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HV033_RS13290	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HV033_RS13295	ENOG4107QMS	site-determining protein
HV033_RS13300	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HV033_RS13305	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HV033_RS13310	ENOG4105CEY	Amp-dependent synthetase and ligase
HV033_RS13315	ENOG4105Y4Z	Outer Membrane Lipoprotein
HV033_RS13320	ENOG41072GX	Peptidase M22 Glycoprotease
HV033_RS13325	ENOG4105DVT	helicase
HV033_RS13330	ENOG4105M4H	endoribonuclease L-psp
HV033_RS13335	ENOG4105X5C	UPF0181 protein
HV033_RS13340	ENOG4105CRQ	synthase (Component I)
HV033_RS13345	ENOG4105P8F	nudix hydrolase
HV033_RS13350	ENOG4105EJQ	L-serine dehydratase
HV033_RS13355	ENOG4107XTP	(EAL) domain protein
HV033_RS13360	ENOG4105EE5	Membrane protein terC
HV033_RS13365	ENOG4105DAS	pts system
HV033_RS13370	ENOG4105ETZ	PTS System
HV033_RS13375	ENOG4105F3R	pts system mannose fructose sorbose family iid
HV033_RS13380	ENOG4108NK4	UPF0266 membrane protein
HV033_RS13385	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HV033_RS13390	ENOG4105DHI	Methyltransferase
HV033_RS13395	ENOG4105CJN	penicillin-binding protein
HV033_RS13410	ENOG4105Q3Y	exported protein
HV033_RS13415	ENOG4106CCY	Protein MgrB homolog
HV033_RS13420	ENOG4105TIK	
HV033_RS13425	ENOG4105J4Q	Transcriptional regulator
HV033_RS13430	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS13435	ENOG4105D0M	Protease HtpX homolog
HV033_RS13440	ENOG4105CN1	protease
HV033_RS13445	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HV033_RS13450	ENOG4108ZGC	gaf domain protein
HV033_RS13455	ENOG4105H2K	paraquat-inducible protein a
HV033_RS13460	ENOG4105DY2	Paraquat-inducible protein b
HV033_RS13465	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HV033_RS13470	ENOG4105WT8	Protein of unknown function (DUF1480)
HV033_RS13475	ENOG4108R1E	Serine threonine protein phosphatase 1
HV033_RS13480	ENOG4108MJ5	VirK protein
HV033_RS13490	ENOG4105NKT	exported protein
HV033_RS13495	ENOG4108PNC	copper resistance
HV033_RS13505	ENOG4105MPK	DNA polymerase III subunit theta
HV033_RS13510	ENOG4108YGA	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HV033_RS13515	ENOG4105UMD	exodeoxyribonuclease X
HV033_RS13520	ENOG4105CUG	Oligopeptidase b
HV033_RS13525	ENOG4108Q2J	Inner membrane protein YebE
HV033_RS13530	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HV033_RS13560	ENOG4108UHU	Aldolase
HV033_RS13565	ENOG4105C01	Dihydroxy-acid dehydratase
HV033_RS13570	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HV033_RS13575	ENOG4106KNT	transcriptional regulator
HV033_RS13580	ENOG4105CA9	Pyruvate kinase
HV033_RS13585	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HV033_RS13590	ENOG4105DR5	peptidase
HV033_RS13595	ENOG4105NXV	High-affinity zinc uptake system protein
HV033_RS13605	ENOG4105FAV	ABC, transporter
HV033_RS13610	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HV033_RS13615	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HV033_RS13620	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HV033_RS13625	ENOG4105CDY	transcriptional regulatory protein
HV033_RS13630	ENOG4108TIT	dATP pyrophosphohydrolase
HV033_RS13635	ENOG4105C9M	aspartyl-trna synthetase
HV033_RS13640	ENOG4105D3W	isochorismatase
HV033_RS13645	ENOG41081XQ	Conserved Protein
HV033_RS13650	ENOG4105WJG	Glutathione
HV033_RS13655	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HV033_RS13660	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HV033_RS13665	ENOG4106N3A	copper homeostasis protein cutc
HV033_RS13670	ENOG4106ZCM	YecM protein
HV033_RS13675	ENOG4105C75	arginyL-tRNA synthetase
HV033_RS13690	ENOG4105F5H	Glycosyl Hydrolase Family 88
HV033_RS13695	ENOG4105CT4	transporter
HV033_RS13700	ENOG4105W13	flagellar protein
HV033_RS13705	ENOG4105D7B	Flagellar biosynthesis protein flha
HV033_RS13710	ENOG4105D00	flagellar biosynthetic protein flhB
HV033_RS13715	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HV033_RS13720	ENOG4108VYJ	response regulator receiver protein
HV033_RS13730	ENOG4105BZU	Histidine kinase
HV033_RS13735	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS13740	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS13770	ENOG4107QJT	sodium dicarboxylate symporter
HV033_RS13775	ENOG4108V3W	Chemotaxis protein, CheW
HV033_RS13780	ENOG4105CBS	Chea signal transduction histidine kinase
HV033_RS13785	ENOG4105ER2	Ompa motb domain protein
HV033_RS13790	ENOG4107RD7	Flagellar Motor Protein, MotA
HV033_RS13795	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HV033_RS13800	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HV033_RS13805	ENOG4108VA4	Universal stress protein
HV033_RS13810	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HV033_RS13815	ENOG4108K4C	ec 3.1.3.12
HV033_RS13820	ENOG4105CNN	ABC, transporter
HV033_RS13830	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
HV033_RS13840	ENOG4108UEC	Ferritin-like protein
HV033_RS13845	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HV033_RS13850	ENOG4105N4N	Protein of unknown function (DUF2766)
HV033_RS13875	ENOG41090A1	ferritin
HV033_RS13880	ENOG4105VVZ	metal-binding protein
HV033_RS13885	ENOG4105E0U	tyrosine-specific transport protein
HV033_RS13890	ENOG4106RHG	Yeca family
HV033_RS13900	ENOG4105C32	Amino acid ABC transporter (Permease)
HV033_RS13905	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HV033_RS13910	ENOG4105C0Z	ABC transporter
HV033_RS13915	ENOG4108IV0	ABC, transporter
HV033_RS13925	ENOG4105DQS	Transcriptional regulator
HV033_RS13960	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HV033_RS13965	ENOG4105WH1	Two component transcriptional regulator luxr family
HV033_RS13970	ENOG4105XVG	cytoplasmic protein
HV033_RS13975	ENOG4105VJY	transcriptional regulator
HV033_RS13980	ENOG4105CDA	abc transporter atp-binding protein
HV033_RS13985	ENOG4105E5Q	amino acid AbC transporter
HV033_RS13990	ENOG4105K6H	D-cysteine desulfhydrase
HV033_RS13995	ENOG4105EAB	amino acid AbC transporter
HV033_RS14000	ENOG4108M9K	flagella biosynthesis protein FliZ
HV033_RS14005	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV033_RS14010	ENOG4105I03	Flagellin
HV033_RS14015	ENOG4105DTS	flagellar hook-associated
HV033_RS14020	ENOG4105MQ3	flagellar protein FliS
HV033_RS14030	ENOG4105E5K	Alpha-amylase
HV033_RS14035	ENOG4108W9D	(LipO)protein
HV033_RS14040	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HV033_RS14045	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HV033_RS14050	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HV033_RS14055	ENOG41090PJ	Flagellar assembly protein
HV033_RS14060	ENOG4108JIR	Flagellum-specific ATP synthase
HV033_RS14065	ENOG4105GSA	Flagellar export protein flij
HV033_RS14070	ENOG4105WF4	Flagellar hook-length control protein
HV033_RS14075	ENOG4107ZI8	flagellar basal body-associated protein flil
HV033_RS14080	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HV033_RS14085	ENOG4105DD5	Flagellar motor switch protein
HV033_RS14090	ENOG4105K0P	flagellar biosynthesis protein
HV033_RS14095	ENOG4105CN7	Flagellar biosynthetic protein FliP
HV033_RS14105	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HV033_RS14110	ENOG4107TKS	colanic acid capsular biosynthesis activation protein A
HV033_RS14120	ENOG4105YX3	cellular response to acidity
HV033_RS14125	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
HV033_RS14135	ENOG4105VNZ	cytoplasmic protein
HV033_RS14140	ENOG4105CKW	Inner membrane protein yedI
HV033_RS14145	ENOG4105FDR	Membrane
HV033_RS14150	ENOG41090BB	DNA mismatch endonuclease (vsr)
HV033_RS14155	ENOG4105DVF	Cytosine-specific methyltransferase
HV033_RS14160	ENOG4105EST	Metal Dependent Phosphohydrolase
HV033_RS14165	ENOG4105FCK	Membrane
HV033_RS14170	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV033_RS14175	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HV033_RS14180	ENOG4108MRH	transcriptional regulatory protein
HV033_RS14200	ENOG4107GFK	fumarate
HV033_RS14215	ENOG4105CSH	Transporter
HV033_RS14225	ENOG4105F04	LysR family Transcriptional regulator
HV033_RS14250	ENOG4105DUU	IucA IucC family protein
HV033_RS14255	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HV033_RS14280	ENOG4107QMH	DNA methylase
HV033_RS14400	ENOG410679B	prophage CP4-57 regulatory protein alpA
HV033_RS14420	ENOG4107R11	Transcriptional regulator
HV033_RS14435	ENOG4108PXI	ErfK YbiS YcfS YnhG
HV033_RS14455	ENOG4105BZS	acriflavin resistance protein
HV033_RS14470	ENOG4105CSH	Transporter
HV033_RS14475	ENOG4105FYV	Amp nucleosidase
HV033_RS14480	ENOG4105DC7	peptidase M24
HV033_RS14490	ENOG4105UQX	Mate efflux family protein
HV033_RS14505	ENOG4105DR8	Membrane
HV033_RS14510	ENOG4108S5C	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity)
HV033_RS14515	ENOG4105EKQ	RNA-directed DNA polymerase
HV033_RS14520	ENOG4105DZ1	carboxypeptidase
HV033_RS14525	ENOG4105CJB	Exodeoxyribonuclease I
HV033_RS14535	ENOG4105CUB	amino acid
HV033_RS14545	ENOG4105EQ1	Transcriptional regulator
HV033_RS14550	ENOG4107SRH	Nad-dependent epimerase dehydratase
HV033_RS14560	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HV033_RS14570	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HV033_RS14575	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HV033_RS14580	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HV033_RS14585	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HV033_RS14590	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HV033_RS14600	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
HV033_RS14615	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HV033_RS14630	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HV033_RS14650	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HV033_RS14660	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HV033_RS14665	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HV033_RS14670	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HV033_RS14675	ENOG4105G1A	colanic acid biosynthesis protein
HV033_RS14680	ENOG4107T8Q	Glycosyl transferase (Group 1
HV033_RS14685	ENOG4105C74	pyruvyl transferase
HV033_RS14690	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HV033_RS14695	ENOG4105D3Q	Sugar transferase
HV033_RS14700	ENOG4107QKV	phosphomannomutase
HV033_RS14705	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HV033_RS14710	ENOG4106CD9	glycosyl transferase group 1
HV033_RS14715	ENOG4105FGF	GDP-mannose mannosyl hydrolase
HV033_RS14720	ENOG4105C30	Nad-dependent epimerase dehydratase
HV033_RS14725	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HV033_RS14730	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HV033_RS14735	ENOG4105ECJ	Glycosyl Transferase
HV033_RS14740	ENOG4108NYJ	Colanic acid
HV033_RS14745	ENOG4107RXY	Glycosyl transferase
HV033_RS14750	ENOG41068PY	Colanic acid biosynthesis acetyltransferase wcaB
HV033_RS14755	ENOG41090RK	glycosyl transferase
HV033_RS14760	ENOG4105D75	Capsular exopolysaccharide family
HV033_RS14765	ENOG4105KJF	protein tyrosine phosphatase
HV033_RS14770	ENOG4105DAY	polysaccharide export protein
HV033_RS14775	ENOG4105EE5	Membrane protein terC
HV033_RS14780	ENOG4108GAE	asmA family
HV033_RS14785	ENOG4105DHP	deoxycytidine triphosphate deaminase
HV033_RS14795	ENOG4105BZU	Histidine kinase
HV033_RS14800	ENOG4105D03	DNA-3-methyladenine glycosylase II
HV033_RS14805	ENOG4105R8A	Heat shock protein
HV033_RS14810	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HV033_RS14815	ENOG4105BZS	acriflavin resistance protein
HV033_RS14820	ENOG4105BZS	acriflavin resistance protein
HV033_RS14825	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS14830	ENOG4105EB3	Histidine kinase
HV033_RS14835	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HV033_RS14840	ENOG4105CFP	Peptidase U32
HV033_RS14855	ENOG4107TE5	Lipid kinase
HV033_RS14860	ENOG4105EIE	fructose-bisphosphate aldolase
HV033_RS14865	ENOG4105EAA	nucleoside
HV033_RS14870	ENOG4108KD5	ADP-ribosylation crystallin J1
HV033_RS14875	ENOG4108TFM	Kinase, PfkB family
HV033_RS14880	ENOG4105FDP	GntR family transcriptional regulator
HV033_RS14885	ENOG4105DWF	phosphomethylpyrimidine kinase
HV033_RS14890	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HV033_RS14910	ENOG4108JPW	Aminotransferase
HV033_RS14915	ENOG4105DY8	decarboxylase
HV033_RS14920	ENOG4108F2G	Chain length determinant protein
HV033_RS14925	ENOG4107ZF2	Phosphatase
HV033_RS14945	ENOG4108Z1S	Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly
HV033_RS14950	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HV033_RS14955	ENOG4105D1F	ATP-binding protein
HV033_RS14960	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HV033_RS14965	ENOG4108W15	Protein of unknown function (DUF1456)
HV033_RS14970	ENOG4108NEV	two component transcriptional regulator, LytTR family
HV033_RS14975	ENOG4108HRK	Histidine kinase
HV033_RS14980	ENOG4108XDN	Transcriptional regulator
HV033_RS14990	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HV033_RS14995	ENOG4108IJ8	ABC transporter
HV033_RS15000	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HV033_RS15005	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HV033_RS15010	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HV033_RS15015	ENOG4105CXG	d-lactate dehydrogenase
HV033_RS15025	ENOG41061WM	D-Alanyl-D-Alanine
HV033_RS15030	ENOG41069YE	inner membrane protein yohC
HV033_RS15035	ENOG4105KHU	inner membrane protein YohD
HV033_RS15040	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HV033_RS15045	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
HV033_RS15050	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HV033_RS15055	ENOG4105VAW	lrga family
HV033_RS15060	ENOG41067MG	lrgb family
HV033_RS15065	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HV033_RS15070	ENOG4107GZ4	SanA protein
HV033_RS15075	ENOG4107SDZ	Galactoside transport system permease protein mglC
HV033_RS15080	ENOG4105C2J	ABC transporter
HV033_RS15090	ENOG41060NJ	transcriptional regulator
HV033_RS15095	ENOG4105DHF	Membrane
HV033_RS15100	ENOG4105EUJ	GTP cyclohydrolase i
HV033_RS15105	ENOG4105CBP	Major Facilitator
HV033_RS15110	ENOG4105C4W	S-formylglutathione hydrolase
HV033_RS15115	ENOG4105D05	Receptor
HV033_RS15120	ENOG4108IQI	permease
HV033_RS15125	ENOG4105DUM	transcriptional regulator, lysR family
HV033_RS15130	ENOG4105HMI	Membrane
HV033_RS15135	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HV033_RS15140	ENOG4105DM4	PTS System
HV033_RS15145	ENOG4105DE4	1-phosphofructokinase
HV033_RS15150	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HV033_RS15160	ENOG4105S8Q	sugar efflux transporter
HV033_RS15165	ENOG4105KRS	Proteinase inhibitor
HV033_RS15170	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HV033_RS15175	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HV033_RS15180	ENOG4105DEI	Mannitol dehydrogenase
HV033_RS15185	ENOG4105CKI	cobalamin synthesis protein
HV033_RS15190	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HV033_RS15195	ENOG4107TT5	NLP P60 protein
HV033_RS15200	ENOG4105CXC	rtn protein
HV033_RS15205	ENOG4105E43	Extracellular solute-binding protein, family 5
HV033_RS15210	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HV033_RS15215	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HV033_RS15220	ENOG4108JQ5	ABC transporter
HV033_RS15225	ENOG4105HG6	
HV033_RS15230	ENOG4105C2C	drug resistance transporter, Bcr CflA
HV033_RS15235	ENOG4105I08	Pseudouridine synthase
HV033_RS15240	ENOG4105CFI	type iii restriction protein res subunit
HV033_RS15245	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HV033_RS15250	ENOG4106V8H	Nucleoid-associated protein
HV033_RS15255	ENOG4105PAN	UPF0352 protein
HV033_RS15260	ENOG4105E68	Sulfatase
HV033_RS15270	ENOG4105S5I	Membrane
HV033_RS15280	ENOG4105DWT	malate dehydrogenase (quinone)
HV033_RS15285	ENOG4105CHH	sulfate transporter
HV033_RS15290	ENOG4105CJW	magnesium transporter
HV033_RS15295	ENOG4105IBP	Cyclic peptide transporter
HV033_RS15300	ENOG4105CF1	Alkylated DNA repair protein
HV033_RS15305	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HV033_RS15320	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HV033_RS15325	ENOG41068CG	regulatoR
HV033_RS15330	ENOG4105BZU	Histidine kinase
HV033_RS15335	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV033_RS15340	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HV033_RS15345	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HV033_RS15350	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HV033_RS15355	ENOG4105XPH	Ferredoxin
HV033_RS15360	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HV033_RS15365	ENOG4105CXY	transporter
HV033_RS15370	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HV033_RS15375	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
HV033_RS15380	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HV033_RS15385	ENOG4108EWA	cinA-like protein
HV033_RS15390	ENOG4108UII	YfaZ family
HV033_RS15395	ENOG4105DHQ	Histidine kinase
HV033_RS15420	ENOG4105CEY	Amp-dependent synthetase and ligase
HV033_RS15425	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HV033_RS15430	ENOG4108IPT	Naphthoate synthase
HV033_RS15435	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HV033_RS15440	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HV033_RS15445	ENOG4105E4F	Isochorismate synthase
HV033_RS15450	ENOG4105TNS	Conserved Protein
HV033_RS15455	ENOG4107YB6	acetyltransferase, (GNAT) family
HV033_RS15460	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HV033_RS15470	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HV033_RS15475	ENOG4105C8S	subunit m
HV033_RS15480	ENOG4105D65	subunit l
HV033_RS15485	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HV033_RS15490	ENOG4107UFS	subunit j
HV033_RS15500	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HV033_RS15505	ENOG4108IEH	NADH dehydrogenase subunit g
HV033_RS15510	ENOG4107QIZ	NADH dehydrogenase
HV033_RS15515	ENOG4105GKE	subunit e
HV033_RS15520	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HV033_RS15525	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HV033_RS15530	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HV033_RS15535	ENOG4107NQ8	LysR family Transcriptional regulator
HV033_RS15540	ENOG4105CHM	Aminotransferase
HV033_RS15545	ENOG4105DK2	UPF0207 protein
HV033_RS15550	ENOG4107QWE	)-transporter
HV033_RS15555	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HV033_RS15560	ENOG4105XWI	UPF0304 protein
HV033_RS15570	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HV033_RS15575	ENOG4105C6K	Malic enzyme
HV033_RS15580	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HV033_RS15585	ENOG4108HHA	Transketolase
HV033_RS15590	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HV033_RS15600	ENOG4106ETB	IIa component
HV033_RS15605	ENOG4105K2J	Transcriptional regulator
HV033_RS15610	ENOG4105PTV	Nudix Hydrolase
HV033_RS15615	ENOG4108RE9	Phosphodiesterase
HV033_RS15620	ENOG4108SHQ	Glutathione S-transferase
HV033_RS15625	ENOG4105CYM	Glutathione S-transferase
HV033_RS15630	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
HV033_RS15635	ENOG4105ECP	epimerase
HV033_RS15640	ENOG4105D9U	N-acetyltransferase
HV033_RS15645	ENOG4108JEH	abc transporter atp-binding protein
HV033_RS15650	ENOG4106YG3	ABC transporter
HV033_RS15655	ENOG4105DSP	amino acid AbC transporter
HV033_RS15660	ENOG4105E89	ABC transporter
HV033_RS15665	ENOG4105E89	ABC transporter
HV033_RS15670	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HV033_RS15675	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HV033_RS15680	ENOG4105E96	Colicin v production protein
HV033_RS15685	ENOG4108S3P	Sporulation domain protein
HV033_RS15690	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HV033_RS15695	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HV033_RS15700	ENOG4105DQR	SNARE associated Golgi
HV033_RS15705	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HV033_RS15710	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HV033_RS15715	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HV033_RS15720	ENOG4106WZ1	flagella biosynthesis regulator
HV033_RS15725	ENOG4105F9N	Major Facilitator Superfamily
HV033_RS15730	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HV033_RS15735	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HV033_RS15740	ENOG4105MH2	YfcL protein
HV033_RS15745	ENOG4108BPE	-transporting atpase
HV033_RS15750	ENOG4105EJ9	Membrane
HV033_RS15755	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HV033_RS15760	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HV033_RS15765	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HV033_RS15770	ENOG4108DG9	Smr protein MutS2
HV033_RS15775	ENOG4108BY2	phosphohistidine phosphatase
HV033_RS15780	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HV033_RS15785	ENOG4105CHU	acetyl-coa acetyltransferase
HV033_RS15790	ENOG4105KZW	UPF0381 protein
HV033_RS15795	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HV033_RS15800	ENOG410903C	(LipO)protein
HV033_RS15805	ENOG4105S64	Formate nitrite transporter
HV033_RS15815	ENOG4105D1S	lipid A biosynthesis
HV033_RS15825	ENOG4105CHM	Aminotransferase
HV033_RS15830	ENOG4108HRK	Histidine kinase
HV033_RS15835	ENOG4105DY9	regulatoR
HV033_RS15840	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HV033_RS15850	ENOG4107RA9	decarboxylase
HV033_RS15855	ENOG4105CPC	Aldo Keto reductase
HV033_RS15865	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HV033_RS15870	ENOG4105D9N	nucleoside
HV033_RS15875	ENOG4108KMM	Diguanylate cyclase
HV033_RS15890	ENOG4105HZG	regulatoR
HV033_RS15895	ENOG4105GXM	Putative transcription regulator (DUF1323)
HV033_RS15900	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HV033_RS15930	ENOG4108M0I	Transcriptional regulator
HV033_RS15935	ENOG4105DHU	Bile acid
HV033_RS15940	ENOG4105VRT	cytoplasmic protein
HV033_RS15945	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HV033_RS15950	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HV033_RS15955	ENOG4105EXN	Sulfate transport protein CysZ
HV033_RS15960	ENOG4105C6T	cysteine synthase
HV033_RS15970	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HV033_RS15975	ENOG4105C5Y	PTS System
HV033_RS15985	ENOG4105C6T	cysteine synthase
HV033_RS15990	ENOG4108IJ6	ABC transporter
HV033_RS15995	ENOG4105ECW	sulfate abc transporter
HV033_RS16000	ENOG4108I5D	sulfate abc transporter
HV033_RS16005	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HV033_RS16010	ENOG4105EZR	dyp-type peroxidase family protein
HV033_RS16015	ENOG4105E7K	(LipO)protein
HV033_RS16020	ENOG4105QZU	Inner membrane protein YfeZ
HV033_RS16025	ENOG4108R6G	acetyltransferase
HV033_RS16030	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HV033_RS16035	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HV033_RS16040	ENOG4105C6K	Malic enzyme
HV033_RS16050	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HV033_RS16055	ENOG4108PVD	exported protein
HV033_RS16060	ENOG4107VIJ	nudix hydrolase
HV033_RS16065	ENOG4105BZ8	glutamate synthase
HV033_RS16070	ENOG4105BZU	Histidine kinase
HV033_RS16075	ENOG4105BZS	acriflavin resistance protein
HV033_RS16085	ENOG4105KUZ	arsenate reductase
HV033_RS16090	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HV033_RS16100	ENOG4106KED	esterase YpfH
HV033_RS16105	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HV033_RS16110	ENOG4105CGZ	zinc metallopeptidase
HV033_RS16115	ENOG4105C8V	SAICAR synthetase
HV033_RS16120	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HV033_RS16130	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HV033_RS16135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV033_RS16140	ENOG4105C02	permease
HV033_RS16145	ENOG4105ERG	peptidase m48, ste24p
HV033_RS16150	ENOG4105K89	arsenate reductase
HV033_RS16175	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HV033_RS16180	ENOG4105C2W	permease
HV033_RS16185	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HV033_RS16190	ENOG4105CS2	ec 3.2.1.21
HV033_RS16200	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HV033_RS16210	ENOG4105C9X	ppx gppa phosphatase
HV033_RS16215	ENOG4105BZU	Histidine kinase
HV033_RS16220	ENOG41062G3	Protein of unknown function (DUF2633)
HV033_RS16235	ENOG4105Z4Q	MltA-interacting MipA family protein
HV033_RS16240	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HV033_RS16260	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HV033_RS16265	ENOG4105UEI	Transcriptional Regulator AraC Family
HV033_RS16285	ENOG4105NVB	glycoside hydrolase, family 19
HV033_RS16310	ENOG4105EKQ	RNA-directed DNA polymerase
HV033_RS16425	ENOG4108TFU	terminase (Small subunit)
HV033_RS16525	ENOG4108PNI	recT protein
HV033_RS16565	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HV033_RS16570	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HV033_RS16575	ENOG4105D4Y	metalloprotease
HV033_RS16585	ENOG4105VPD	cellular component movement
HV033_RS16590	ENOG4105DUX	Transporter
HV033_RS16595	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HV033_RS16600	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HV033_RS16605	ENOG4105N21	Membrane
HV033_RS16610	ENOG4105CUT	histidyl-tRNA synthetase
HV033_RS16615	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HV033_RS16625	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HV033_RS16630	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HV033_RS16640	ENOG4107KGK	dmso reductase anchor subunit
HV033_RS16645	ENOG4105QAX	Iron-sulfur
HV033_RS16650	ENOG4107QY8	reductase
HV033_RS16655	ENOG4108JQB	penicillin-binding protein 1C
HV033_RS16660	ENOG4105DN3	alpha-2-macroglobulin domain protein
HV033_RS16665	ENOG4105CI1	PTS System
HV033_RS16675	ENOG4105KHC	sulfurtransferase
HV033_RS16680	ENOG4108Q3X	Transcriptional regulator
HV033_RS16685	ENOG4105YYA	enhanced serine sensitivity protein SseB
HV033_RS16690	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HV033_RS16695	ENOG4105WVQ	Fe-S assembly protein IscX
HV033_RS16700	ENOG4108ZIT	Ferredoxin, 2FE-2S
HV033_RS16705	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HV033_RS16710	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HV033_RS16715	ENOG4108Z4V	iron-sulfur cluster assembly
HV033_RS16720	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HV033_RS16725	ENOG4105C3J	Cysteine desulfurase
HV033_RS16730	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HV033_RS16735	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HV033_RS16740	ENOG4105ECY	inositol monophosphatase
HV033_RS16745	ENOG4105D7X	high-affinity nickel-transporter
HV033_RS16755	ENOG4108MN2	Stationary phase inducible protein CsiE
HV033_RS16760	ENOG4105D8G	Major Facilitator superfamily
HV033_RS16765	ENOG4108SB3	DoxX Family
HV033_RS16770	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HV033_RS16775	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HV033_RS16780	ENOG4108YZA	Nitrogen regulatory protein pii
HV033_RS16785	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HV033_RS16790	ENOG4108SKK	alpha helix protein
HV033_RS16795	ENOG4107WP9	Histidine kinase
HV033_RS16800	ENOG4108ETH	Formylglycinamide ribotide synthetase
HV033_RS16805	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HV033_RS16810	ENOG4108Z6B	deaminase
HV033_RS16815	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
HV033_RS16825	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV033_RS16830	ENOG4106G6Q	Transcriptional regulator
HV033_RS16835	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HV033_RS16840	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HV033_RS16845	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HV033_RS16850	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HV033_RS16855	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HV033_RS16860	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HV033_RS16865	ENOG4105C3F	Signal peptidase i
HV033_RS16875	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HV033_RS16895	ENOG4108IYU	L-aspartate oxidase
HV033_RS16900	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HV033_RS16905	ENOG4105C1J	atp-dependent rna helicase
HV033_RS16910	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HV033_RS16915	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HV033_RS16920	ENOG4105EIB	trna rrna methyltransferase
HV033_RS16925	ENOG4105K63	Thioredoxin
HV033_RS16930	ENOG4106IUH	DTW domain containing protein
HV033_RS16935	ENOG4105CD5	CoA-binding domain protein
HV033_RS16940	ENOG4105JIM	Phosphatidylserine synthase
HV033_RS16945	ENOG4105T42	(LipO)protein
HV033_RS16950	ENOG4105CSH	Transporter
HV033_RS16980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HV033_RS16985	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HV033_RS16990	ENOG4105C34	Pseudouridine synthase
HV033_RS16995	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV033_RS17000	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HV033_RS17010	ENOG4105CQC	Prephenate dehydratase
HV033_RS17020	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HV033_RS17025	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HV033_RS17030	ENOG4108WS1	
HV033_RS17035	ENOG4108KHX	Diguanylate cyclase
HV033_RS17040	ENOG41090EK	ompa motb domain protein
HV033_RS17055	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HV033_RS17060	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HV033_RS17065	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HV033_RS17070	ENOG4105K5M	30s ribosomal protein S16
HV033_RS17075	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV033_RS17080	ENOG4106KVJ	cytochrome C assembly protein
HV033_RS17085	ENOG4108JU6	CBS domain protein
HV033_RS17090	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HV033_RS17095	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HV033_RS17100	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HV033_RS17105	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HV033_RS17110	ENOG4105VDB	UPF0125 protein
HV033_RS17115	ENOG4108Z1B	Cyclase dehydrase
HV033_RS17130	ENOG4105Y50	Virulence Protein
HV033_RS17230	ENOG4105EFC	phage portal protein HK97 family
HV033_RS17235	ENOG4105CAR	Terminase, large subunit
HV033_RS17265	ENOG4105NVB	glycoside hydrolase, family 19
HV033_RS17285	ENOG4105HGD	Antitermination protein
HV033_RS17305	ENOG4105W7J	DNA binding
HV033_RS17350	ENOG4107R08	Integrase
HV033_RS17375	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HV033_RS17395	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS17410	ENOG4108R85	Short chain dehydrogenase
HV033_RS17415	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HV033_RS17430	ENOG4105CWB	LysR family transcriptional Regulator
HV033_RS17440	ENOG4105E7U	AraC family transcriptional regulator
HV033_RS17445	ENOG4107GJV	short-chain dehydrogenase reductase
HV033_RS17450	ENOG4105EMU	Dehydrogenase
HV033_RS17455	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS17465	ENOG4105ETT	transcriptional Regulator, LysR family
HV033_RS17470	ENOG4105DZC	cytosine deaminase
HV033_RS17475	ENOG4105C5B	carbamate kinase
HV033_RS17485	ENOG4107REC	cytoplasmic protein
HV033_RS17490	ENOG4107R1Q	Membrane protein FdrA
HV033_RS17495	ENOG4107SNB	ankyrin repeat protein YahD
HV033_RS17500	ENOG4108NUU	Transcriptional regulator
HV033_RS17505	ENOG4105VPI	YqaE family transport protein
HV033_RS17510	ENOG4108V62	Rhodanese domain protein
HV033_RS17520	ENOG4108X73	DNA- binding protein
HV033_RS17525	ENOG4108RNS	Exports L-alanine (By similarity)
HV033_RS17530	ENOG4108WMJ	Protein of unknown function (DUF2002)
HV033_RS17535	ENOG4108ZQZ	Bacterial protein of unknown function (DUF883)
HV033_RS17540	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HV033_RS17545	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HV033_RS17550	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HV033_RS17555	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HV033_RS17560	ENOG4108IJ7	Glycine betaine
HV033_RS17565	ENOG4108HQS	Glycine betaine
HV033_RS17570	ENOG4105GIJ	Glycine betaine
HV033_RS17580	ENOG4105NTK	Transcriptional repressor Mpra
HV033_RS17585	ENOG4105CW7	secretion protein, HlyD family
HV033_RS17590	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS17595	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HV033_RS17600	ENOG4105D9M	gamma-glutamylcysteine synthetase
HV033_RS17605	ENOG4105W39	Membrane
HV033_RS17610	ENOG4107VXZ	Hydrolase
HV033_RS17640	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HV033_RS17645	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HV033_RS17655	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HV033_RS17660	ENOG4107TH8	cina domain protein
HV033_RS17670	ENOG4105CC5	ABC transporter
HV033_RS17675	ENOG4105DIK	(ABC) transporter
HV033_RS17680	ENOG4105CVE	Lytic murein transglycosylase
HV033_RS17685	ENOG410787A	Pts system, glucitol sorbitol-specific
HV033_RS17690	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HV033_RS17695	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HV033_RS17700	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
HV033_RS17705	ENOG4105J92	DNA-binding transcriptional activator GutM
HV033_RS17710	ENOG410804X	Transcriptional regulator
HV033_RS17720	ENOG4108JUA	Transcriptional regulator
HV033_RS17725	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
HV033_RS17730	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HV033_RS17740	ENOG4105C8H	hydrogenase maturation protein Hypf
HV033_RS17745	ENOG4108RC0	Electron transport protein
HV033_RS17750	ENOG4105DDV	Transcriptional regulator (LacI family
HV033_RS17755	ENOG4105C5Y	PTS System
HV033_RS17760	ENOG4105CS2	ec 3.2.1.21
HV033_RS17765	ENOG4108MG9	hydrogenase 3 maturation protease
HV033_RS17770	ENOG4105I6X	formate hydrogenlyase maturation
HV033_RS17775	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HV033_RS17780	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
HV033_RS17785	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HV033_RS17790	ENOG4107TDF	Formate hydrogenlyase subunit 4
HV033_RS17795	ENOG4107R30	NADH dehydrogenase
HV033_RS17800	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HV033_RS17805	ENOG4108VRC	Formate hydrogenlyase regulatory protein hycA
HV033_RS17810	ENOG410816D	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HV033_RS17815	ENOG4107RSS	Hydrogenase accessory protein HypB
HV033_RS17820	ENOG41083WG	hydrogenase assembly chaperone
HV033_RS17825	ENOG4105CQS	hydrogenase expression formation protein HypD
HV033_RS17830	ENOG4105C45	hydrogenase expression formation protein (HypE)
HV033_RS17840	ENOG4105VXR	cytoplasmic protein
HV033_RS17850	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HV033_RS17855	ENOG4105KZM	cytoplasmic protein
HV033_RS17860	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HV033_RS17865	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HV033_RS17875	ENOG4105JQN	Transcriptional regulator
HV033_RS17880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS17895	ENOG4108K5P	(LipO)protein
HV033_RS17905	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HV033_RS17910	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HV033_RS17915	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HV033_RS17920	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HV033_RS17925	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HV033_RS17930	ENOG4105N0Z	inner membrane protein ygbE
HV033_RS17935	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
HV033_RS17945	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HV033_RS17950	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HV033_RS17955	ENOG4108MXK	alkaline phosphatase isozyme conversion
HV033_RS17960	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HV033_RS17970	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HV033_RS17975	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HV033_RS17980	ENOG41075H3	AraC family transcriptional regulator
HV033_RS17985	ENOG4105CH2	amidohydrolase
HV033_RS17995	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HV033_RS18000	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HV033_RS18005	ENOG4105CI1	PTS System
HV033_RS18010	ENOG4105QEK	Transcriptional regulator
HV033_RS18015	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HV033_RS18020	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HV033_RS18025	ENOG4105DXN	mazG family
HV033_RS18030	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HV033_RS18035	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HV033_RS18040	ENOG4105BZU	Histidine kinase
HV033_RS18045	ENOG4105BZW	Glycerate kinase
HV033_RS18050	ENOG4105EQX	glucarate dehydratase
HV033_RS18055	ENOG4105EQX	glucarate dehydratase
HV033_RS18060	ENOG4105DJB	Major Facilitator Superfamily
HV033_RS18065	ENOG4105QDK	Flavodoxin
HV033_RS18070	ENOG4105DR9	pseudouridine synthase
HV033_RS18075	ENOG4105WP7	tRNA pseudouridine synthase C
HV033_RS18080	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HV033_RS18090	ENOG4105EWT	decarboxylase family
HV033_RS18095	ENOG4105C44	Serine transporter
HV033_RS18100	ENOG4105EJQ	L-serine dehydratase
HV033_RS18105	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HV033_RS18110	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HV033_RS18115	ENOG4105M08	Membrane
HV033_RS18120	ENOG4105ETT	transcriptional Regulator, LysR family
HV033_RS18125	ENOG4105M5B	(LipO)protein
HV033_RS18130	ENOG4105C9B	Cysteine desulfurase
HV033_RS18135	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HV033_RS18140	ENOG4105CUZ	uba thif-type nad fad binding protein
HV033_RS18145	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HV033_RS18165	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HV033_RS18170	ENOG4107QZM	n-acetylglutamate synthase
HV033_RS18175	ENOG4107QYX	exodeoxyribonuclease v alpha
HV033_RS18180	ENOG4107QKA	exodeoxyribonuclease V beta
HV033_RS18185	ENOG4107QXK	peptidase
HV033_RS18190	ENOG4105DSY	exodeoxyribonuclease V, gamma
HV033_RS18195	ENOG4105RVB	Prepilin peptidase dependent protein c
HV033_RS18200	ENOG4105SEN	Protein of unknown function (DUF2509) 
HV033_RS18205	ENOG4105JCS	prepilin peptidase dependent protein
HV033_RS18210	ENOG4105IPU	prepilin peptidase dependent protein A
HV033_RS18215	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HV033_RS18220	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HV033_RS18225	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HV033_RS18230	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HV033_RS18235	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HV033_RS18240	ENOG4105SUV	lipoprotein YgdR
HV033_RS18245	ENOG4105CPC	Aldo Keto reductase
HV033_RS18250	ENOG4107S74	Lysophospholipid transporter LplT
HV033_RS18255	ENOG4105CEY	Amp-dependent synthetase and ligase
HV033_RS18260	ENOG41060NJ	transcriptional regulator
HV033_RS18270	ENOG4107YCY	Transcriptional regulator
HV033_RS18275	ENOG4105CS2	ec 3.2.1.21
HV033_RS18280	ENOG4105CK1	PTS System
HV033_RS18285	ENOG4105DDV	Transcriptional regulator (LacI family
HV033_RS18295	ENOG4105RQF	LysR family Transcriptional regulator
HV033_RS18310	ENOG4108QY5	Ferric enterobactin transport protein
HV033_RS18315	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HV033_RS18320	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HV033_RS18335	ENOG4107QNK	)-transporter
HV033_RS18340	ENOG4105CHR	reductase
HV033_RS18345	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HV033_RS18350	ENOG4105CAZ	oligogalacturonide lyase
HV033_RS18355	ENOG4108PU9	oligogalacturonate-specific porin
HV033_RS18360	ENOG4105CHU	acetyl-coa acetyltransferase
HV033_RS18375	ENOG4108MHD	transport protein
HV033_RS18380	ENOG410830R	acetyltransferase
HV033_RS18385	ENOG4105VR1	Pfam:DUF1271
HV033_RS18395	ENOG4108Z9Z	response to DNA damage stimulus
HV033_RS18400	ENOG4108N8X	transition metal ion binding
HV033_RS18405	ENOG4105WEF	catalase
HV033_RS18410	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HV033_RS18415	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HV033_RS18420	ENOG4105CG3	alpha amylase, catalytic region
HV033_RS18430	ENOG4108WTK	competence damage-inducible protein
HV033_RS18445	ENOG4108YDI	single-species biofilm formation on inanimate substrate
HV033_RS18450	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HV033_RS18455	ENOG4105EUZ	Beta-lactamase domain protein
HV033_RS18470	ENOG4108PNB	DNA-binding transcriptional regulator
HV033_RS18475	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HV033_RS18480	ENOG4108NIW	Leucine export protein LeuE
HV033_RS18495	ENOG4105MN3	Resolvase
HV033_RS18605	ENOG4108K5P	(LipO)protein
HV033_RS18610	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HV033_RS18615	ENOG4105CRK	lysyL-tRNA synthetase
HV033_RS18625	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HV033_RS18630	ENOG4105T95	Thiol disulfide interChange protein
HV033_RS18635	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HV033_RS18640	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HV033_RS18645	ENOG4108YDB	Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB
HV033_RS18650	ENOG4105Y75	tpr repeat protein
HV033_RS18655	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HV033_RS18660	ENOG4108UT2	hemolysin iii
HV033_RS18665	ENOG4108Q3X	Transcriptional regulator
HV033_RS18670	ENOG4105CS2	ec 3.2.1.21
HV033_RS18690	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV033_RS18695	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HV033_RS18700	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HV033_RS18710	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HV033_RS18715	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HV033_RS18720	ENOG4105D0A	hydroxylase
HV033_RS18725	ENOG4107RAQ	aminopeptidase
HV033_RS18735	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HV033_RS18745	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HV033_RS18750	ENOG4108JQ1	Dehydrogenase
HV033_RS18755	ENOG4105E66	phosphoriboisomerase A
HV033_RS18760	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HV033_RS18765	ENOG4105MPN	Membrane
HV033_RS18770	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HV033_RS18775	ENOG4105D64	Mechanosensitive ion channel
HV033_RS18780	ENOG4105D2N	Aldolase
HV033_RS18785	ENOG4105BZA	Phosphoglycerate kinase
HV033_RS18790	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HV033_RS18795	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HV033_RS18800	ENOG4108K0D	peptidase, M48
HV033_RS18815	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
HV033_RS18820	ENOG4105CHR	reductase
HV033_RS18825	ENOG410832A	alpha/beta hydrolase fold
HV033_RS18840	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HV033_RS18850	ENOG4108FUF	Transcriptional regulator, IclR family
HV033_RS18855	ENOG4105CHR	reductase
HV033_RS18880	ENOG4105CYW	agmatinase
HV033_RS18885	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HV033_RS18900	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HV033_RS18905	ENOG4107QNK	)-transporter
HV033_RS18910	ENOG4105GPY	SprT protein
HV033_RS18915	ENOG4105RWS	endonuclease I
HV033_RS18920	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HV033_RS18925	ENOG4105D7Z	glutathione synthase
HV033_RS18930	ENOG4108UJU	UPF0301 protein
HV033_RS18940	ENOG4105CZX	twitching motility protein
HV033_RS18945	ENOG4105DFA	alanine racemase domain protein
HV033_RS18950	ENOG4108VIA	integral membrane protein
HV033_RS18955	ENOG4105VZ9	UPF0235 protein
HV033_RS18965	ENOG4105CSA	Coproporphyrinogen iii oxidase
HV033_RS18970	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HV033_RS18975	ENOG4105K33	Periplasmic Protein
HV033_RS18980	ENOG41090ED	Protein with unknown function (DUF469)
HV033_RS18990	ENOG4105CEN	a g-specific adenine glycosylase
HV033_RS18995	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HV033_RS19000	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HV033_RS19005	ENOG4105EAA	nucleoside
HV033_RS19010	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HV033_RS19020	ENOG4105CHY	citrate lyase, alpha
HV033_RS19025	ENOG4105CI0	Citrate lyase
HV033_RS19030	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HV033_RS19035	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HV033_RS19040	ENOG4105ERH	Fumarylacetoacetate hydrolase
HV033_RS19045	ENOG4105D2K	citrate carrier protein
HV033_RS19050	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HV033_RS19055	ENOG4106YYS	transcriptional regulatory protein
HV033_RS19060	ENOG4105CXN	decarboxylase
HV033_RS19065	ENOG4108UQV	Membrane
HV033_RS19160	ENOG4105BZU	Histidine kinase
HV033_RS19165	ENOG4105WH1	Two component transcriptional regulator luxr family
HV033_RS19185	ENOG4108TUY	outer membrane protein PgaA
HV033_RS19195	ENOG4105CND	Glycosyl transferase, family 2
HV033_RS19205	ENOG4106032	Glutathionylspermidine synthase
HV033_RS19210	ENOG4105CYM	Glutathione S-transferase
HV033_RS19215	ENOG4107EDW	L-fucose operon activator
HV033_RS19220	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS19240	ENOG4105ZIA	Phage protein gp16
HV033_RS19355	ENOG4105CF2	Mu-like prophage FluMu protein GP28
HV033_RS19365	ENOG4108QUU	Morphogenesis Protein
HV033_RS19480	ENOG4105UZW	Tail fiber assembly protein
HV033_RS19485	ENOG4108US3	tail fiber assembly
HV033_RS19495	ENOG4108C33	Resolvase
HV033_RS19505	ENOG4108TEB	UPF0114 protein
HV033_RS19525	ENOG4108ZZF	transport protein (ExbD)
HV033_RS19530	ENOG4105CWK	Biopolymer transport protein, ExbB
HV033_RS19535	ENOG4105C28	cystathionine
HV033_RS19540	ENOG4108K81	inner membrane protein YghB
HV033_RS19545	ENOG4105CF7	AraC family transcriptional regulator
HV033_RS19550	ENOG4108I6A	alcohol dehydrogenase
HV033_RS19555	ENOG4105CV8	reductase
HV033_RS19595	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HV033_RS19640	ENOG4105E2A	Dehydrogenase
HV033_RS19665	ENOG4107RT3	EamA-like transporter family
HV033_RS19675	ENOG4108YXQ	IS66 Orf2 family protein
HV033_RS19680	ENOG4105E5H	Transposase
HV033_RS19685	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HV033_RS19690	ENOG4105EQ2	LysR family Transcriptional regulator
HV033_RS19695	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HV033_RS19700	ENOG4105WAB	arsR family transcriptional regulator
HV033_RS19740	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HV033_RS19745	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HV033_RS19750	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV033_RS19755	ENOG4105H4F	exported protein
HV033_RS19760	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HV033_RS19765	ENOG4105DHQ	Histidine kinase
HV033_RS19770	ENOG4105NF4	modulator of drug activity
HV033_RS19775	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HV033_RS19780	ENOG4109066	lysm domain bon superfamily protein
HV033_RS19790	ENOG4105EP8	Glycosyl Hydrolase Family 88
HV033_RS19795	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HV033_RS19820	ENOG4105EHG	Permease protein
HV033_RS19825	ENOG4105DQ5	transport system permease protein
HV033_RS19830	ENOG4105E0A	ABC, transporter
HV033_RS19840	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HV033_RS19845	ENOG4105IPS	esterase
HV033_RS19850	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HV033_RS19855	ENOG4108SX3	cytoplasmic protein
HV033_RS19860	ENOG41087AY	ADP-Ribose pyrophosphatase
HV033_RS19870	ENOG4105F1G	UPF0441 protein
HV033_RS19875	ENOG4106032	Glutathionylspermidine synthase
HV033_RS19880	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HV033_RS19890	ENOG4106UBK	fimbrial-like adhesin protein
HV033_RS19895	ENOG4106PG1	outer membrane usher protein
HV033_RS19900	ENOG4108TTM	chaperone
HV033_RS19905	ENOG4108MY7	Fimbrial
HV033_RS19910	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HV033_RS19915	ENOG4105W0Z	cytoplasmic protein
HV033_RS19920	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HV033_RS19925	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HV033_RS19930	ENOG4105I7R	Adenylate cyclase
HV033_RS19935	ENOG4106MWK	domain protein
HV033_RS19940	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HV033_RS19950	ENOG4107ZVW	dihydroneopterin aldolase
HV033_RS19960	ENOG4105C54	Major Facilitator superfamily
HV033_RS19965	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HV033_RS19970	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HV033_RS19975	ENOG4105KI2	Urea amidohydrolase subunit beta
HV033_RS19980	ENOG4105CQM	Urea amidohydrolase subunit alpha
HV033_RS19985	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HV033_RS19995	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HV033_RS20000	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HV033_RS20015	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HV033_RS20020	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV033_RS20025	ENOG4108VCA	G U mismatch-specific DNA glycosylase
HV033_RS20035	ENOG4105ZTC	transcriptional activator, Ogr delta
HV033_RS20075	ENOG4105PTU	response to oxidative stress
HV033_RS20170	ENOG4105ED4	portal protein
HV033_RS20180	ENOG4105F2I	Transposase
HV033_RS20195	ENOG4105VZ1	Replication Protein
HV033_RS20210	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HV033_RS20245	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HV033_RS20280	ENOG4105Q26	Siderophore-interacting protein
HV033_RS20285	ENOG4105NTW	Transcriptional regulator
HV033_RS20290	ENOG4105C8Q	Methyl-accepting chemotaxis
HV033_RS20295	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HV033_RS20300	ENOG4105C8Y	Acetylornithine aminotransferase
HV033_RS20305	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
HV033_RS20310	ENOG41061GT	Aldolase
HV033_RS20315	ENOG4105D4B	ABC, transporter
HV033_RS20320	ENOG4105F5R	ABC transporter
HV033_RS20325	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
HV033_RS20330	ENOG4105C2J	ABC transporter
HV033_RS20335	ENOG4105DKT	Transcriptional regulator
HV033_RS20340	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
HV033_RS20345	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HV033_RS20350	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HV033_RS20355	ENOG4108VKG	metal-dependent hydrolase
HV033_RS20360	ENOG4105EE0	oxidoreductase
HV033_RS20365	ENOG4105DU1	integral membrane protein, terc
HV033_RS20375	ENOG4105CTX	dehydratase
HV033_RS20385	ENOG4105DPW	Major facilitator superfamily MFS_1
HV033_RS20390	ENOG4107YCY	Transcriptional regulator
HV033_RS20395	ENOG4106W5V	Membrane
HV033_RS20400	ENOG4105IYR	Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity)
HV033_RS20405	ENOG4105WAY	exported protein
HV033_RS20410	ENOG4105NE1	Conserved Protein
HV033_RS20415	ENOG41090KG	Inner membrane protein YqjE
HV033_RS20420	ENOG4105YJD	
HV033_RS20425	ENOG4108VBZ	doxx family
HV033_RS20430	ENOG4105CHF	Glutathione S-transferase
HV033_RS20435	ENOG4105KAF	membrAne
HV033_RS20440	ENOG4105CWB	LysR family transcriptional Regulator
HV033_RS20445	ENOG4108CNN	domain protein
HV033_RS20455	ENOG4105C44	Serine transporter
HV033_RS20460	ENOG4105C6N	Formate acetyltransferase
HV033_RS20465	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HV033_RS20470	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
HV033_RS20490	ENOG410811B	TRANSCRIPTIONal
HV033_RS20500	ENOG4105BZW	Glycerate kinase
HV033_RS20505	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HV033_RS20510	ENOG4105CNV	Aldolase
HV033_RS20515	ENOG4105CTX	dehydratase
HV033_RS20520	ENOG4105E98	transcriptional regulator DeoR family
HV033_RS20525	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HV033_RS20530	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HV033_RS20540	ENOG4105F3R	pts system mannose fructose sorbose family iid
HV033_RS20545	ENOG4105YHU	PTS system
HV033_RS20550	ENOG4105CE4	GlcNAc 6-P deacetylase
HV033_RS20555	ENOG4105E70	isomerase
HV033_RS20560	ENOG4105D2N	Aldolase
HV033_RS20565	ENOG4105CI1	PTS System
HV033_RS20580	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HV033_RS20585	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HV033_RS20590	ENOG41082RQ	UPF0102 protein
HV033_RS20595	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HV033_RS20600	ENOG4105W4M	Transport-associated protein
HV033_RS20605	ENOG4107S21	permease
HV033_RS20610	ENOG4105K4T	epimerase
HV033_RS20615	ENOG4107R7Y	intracellular protease Pfpi family
HV033_RS20620	ENOG4108ZPB	UPF0306 protein
HV033_RS20625	ENOG41082IR	Excinuclease ABC C subunit domain protein
HV033_RS20630	ENOG4108YYD	acetyltransferase
HV033_RS20650	ENOG4105DEN	Luciferase family
HV033_RS20655	ENOG4105CIC	tryptophan-specific transport protein
HV033_RS20660	ENOG4105C1J	atp-dependent rna helicase
HV033_RS20675	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HV033_RS20680	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HV033_RS20685	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HV033_RS20690	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HV033_RS20695	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HV033_RS20700	ENOG4105CHV	Transcription elongation factor NusA
HV033_RS20705	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HV033_RS20715	ENOG4105CDH	Citrulline--aspartate ligase
HV033_RS20725	ENOG4105NTZ	Preprotein translocase subunit SecG
HV033_RS20730	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HV033_RS20735	ENOG4105EEI	dihydropteroate synthase
HV033_RS20740	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HV033_RS20745	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HV033_RS20750	ENOG4105HBR	Rna-binding protein
HV033_RS20755	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HV033_RS20760	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HV033_RS20775	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HV033_RS20780	ENOG4105QYV	Membrane
HV033_RS20785	ENOG4105K46	50S ribosomal protein l27
HV033_RS20790	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HV033_RS20795	ENOG4105EAH	synthase
HV033_RS20800	ENOG4105HVQ	Regulatory factor of maltose metabolism
HV033_RS20805	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HV033_RS20810	ENOG4105VFK	BolA family
HV033_RS20815	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
HV033_RS20820	ENOG4105E3I	toluene tolerance
HV033_RS20825	ENOG4107PE3	Mammalian cell entry related domain protein
HV033_RS20830	ENOG4105CY3	ABC transporter, permease
HV033_RS20835	ENOG4105DHJ	ABC, transporter
HV033_RS20840	ENOG4105FEU	K -dependent Na -Ca exchanger
HV033_RS20845	ENOG4105C2X	Arabinose 5-phosphate isomerase
HV033_RS20850	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HV033_RS20855	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HV033_RS20860	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HV033_RS20865	ENOG4108IUZ	ABC transporter
HV033_RS20870	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV033_RS20875	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HV033_RS20880	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HV033_RS20885	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HV033_RS20890	ENOG41080Z8	PHOSPHOCARRIER protein
HV033_RS20895	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HV033_RS20900	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HV033_RS20905	ENOG4105BZU	Histidine kinase
HV033_RS20910	ENOG4108K5H	permease YjgP YjgQ family protein
HV033_RS20915	ENOG4108M8S	permease YjgP YjgQ family protein
HV033_RS20920	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HV033_RS20925	ENOG4105MYG	DNA polymerase iii, chi subunit
HV033_RS20930	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HV033_RS20935	ENOG4108MJ3	acetyltransferase
HV033_RS20940	ENOG4105DQ4	alcohol dehydrogenase
HV033_RS20950	ENOG4105D7A	ATP-binding protein
HV033_RS20955	ENOG4105N5T	Radical SAM Protein
HV033_RS20960	ENOG4105CBC	glutamate synthase
HV033_RS20965	ENOG4105BZ8	glutamate synthase
HV033_RS20970	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HV033_RS20975	ENOG4105DZC	cytosine deaminase
HV033_RS20980	ENOG4105UMR	response to DNA damage stimulus
HV033_RS20990	ENOG4105E6S	usher protein(
HV033_RS20995	ENOG4108S1B	Periplasmic chaperone protein
HV033_RS21000	ENOG4106AJS	Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon
HV033_RS21005	ENOG4106AJS	Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon
HV033_RS21010	ENOG4105KB2	stringent starvation protein b
HV033_RS21015	ENOG4107MKT	Stringent starvation protein a
HV033_RS21020	ENOG4108UJD	30S ribosomal protein S9
HV033_RS21030	ENOG4105D6Z	AFG1 family ATPase
HV033_RS21035	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HV033_RS21040	ENOG4105C0H	protease
HV033_RS21045	ENOG4105C0H	protease
HV033_RS21055	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HV033_RS21060	ENOG4105RID	UPF0379 protein yhcN
HV033_RS21065	ENOG4105UNR	(Barnase) inhibitor
HV033_RS21070	ENOG4105C26	Dehydrogenase
HV033_RS21075	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
HV033_RS21085	ENOG4105ZQC	membrane protein AaeX
HV033_RS21090	ENOG4105CR8	Transcriptional regulator
HV033_RS21095	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HV033_RS21100	ENOG4105QD6	exported protein
HV033_RS21105	ENOG4105C03	ribonuclease
HV033_RS21115	ENOG4105VQ7	Rod shape-determining protein MreD
HV033_RS21120	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HV033_RS21130	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HV033_RS21135	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HV033_RS21145	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HV033_RS21150	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HV033_RS21155	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HV033_RS21160	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HV033_RS21165	ENOG4105RG0	Membrane
HV033_RS21170	ENOG4108IA2	Sodium pantothenate symporter
HV033_RS21185	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HV033_RS21195	ENOG41061ME	transport protein
HV033_RS21200	ENOG4105BZU	Histidine kinase
HV033_RS21205	ENOG4108XG4	DNA-binding transcriptional regulator
HV033_RS21210	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HV033_RS21215	ENOG4105BZS	acriflavin resistance protein
HV033_RS21220	ENOG4105XCM	membrane LIPOPROTEIN
HV033_RS21255	ENOG4108Z0R	Transferase
HV033_RS21260	ENOG4105SG3	Protein of unknown function (DUF1488)
HV033_RS21265	ENOG4105E2X	shikimate dehydrogenase
HV033_RS21270	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HV033_RS21275	ENOG4108WI1	Dna topoisomerase
HV033_RS21280	ENOG4108RPN	Protein smg homolog
HV033_RS21285	ENOG4105C79	DNA protecting protein DprA
HV033_RS21290	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HV033_RS21295	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HV033_RS21300	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HV033_RS21305	ENOG4105C1A	potassium transporter peripheral membrane
HV033_RS21310	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HV033_RS21315	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HV033_RS21320	ENOG4105W1Y	Transcriptional regulator
HV033_RS21325	ENOG4105VTS	DnaJ-like, subfamily C
HV033_RS21335	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HV033_RS21340	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HV033_RS21345	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HV033_RS21355	ENOG41067V7	50S ribosomal protein L36
HV033_RS21360	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HV033_RS21370	ENOG4105VPB	50S ribosomal protein L30
HV033_RS21385	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HV033_RS21390	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HV033_RS21395	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HV033_RS21405	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HV033_RS21410	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HV033_RS21420	ENOG41083MP	50s ribosomal protein l29
HV033_RS21425	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HV033_RS21435	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HV033_RS21475	ENOG4108UQY	Iron-storage protein
HV033_RS21480	ENOG4105W53	bacterioferritin-associated ferredoxin
HV033_RS21485	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HV033_RS21490	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HV033_RS21505	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HV033_RS21510	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HV033_RS21515	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HV033_RS21520	ENOG4105WWK	YheO domain protein
HV033_RS21525	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HV033_RS21530	ENOG4105VRX	Protein slyX homolog
HV033_RS21535	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HV033_RS21540	ENOG4105VKU	nucleicacid-binding protein
HV033_RS21545	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HV033_RS21550	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HV033_RS21555	ENOG4105C5H	ABC transporter
HV033_RS21560	ENOG4108K70	Transcriptional regulator
HV033_RS21565	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HV033_RS21570	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
HV033_RS21575	ENOG4107TT2	Auxin Efflux Carrier
HV033_RS21605	ENOG4105DNZ	Alpha Beta Hydrolase
HV033_RS21610	ENOG4105YP7	UPF0270 protein
HV033_RS21615	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HV033_RS21620	ENOG4108UKZ	OsmC family
HV033_RS21625	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HV033_RS21630	ENOG410613R	integral membrane protein, YccS YhfK family
HV033_RS21635	ENOG4105C8Y	Acetylornithine aminotransferase
HV033_RS21640	ENOG4105DDQ	anthranilate synthase
HV033_RS21645	ENOG4105MZU	cell filamentation protein
HV033_RS21650	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HV033_RS21655	ENOG4106DTQ	Protein TsgA homolog
HV033_RS21660	ENOG4107QZF	nitrite reductase NADPH large subunit
HV033_RS21665	ENOG4105WZK	nitrite reductase NADPH small subunit
HV033_RS21670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HV033_RS21675	ENOG4105VYH	
HV033_RS21680	ENOG4105C31	Tryptophanyl-tRNA synthetase
HV033_RS21690	ENOG4105DJV	ribulose-phosphate 3-epimerase
HV033_RS21695	ENOG4105DFE	Dna adenine methylase
HV033_RS21700	ENOG4105EGB	membrane protein DamX
HV033_RS21705	ENOG4105D49	3-dehydroquinate synthase
HV033_RS21710	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HV033_RS21715	ENOG4105E4G	Type IV pilus
HV033_RS21735	ENOG4108U1Q	Pilus assembly protein
HV033_RS21740	ENOG4108JQC	penicillin-binding protein 1A
HV033_RS21745	ENOG4107RK2	ADP-ribose diphosphatase NudE
HV033_RS21750	ENOG4105DQY	intracellular growth attenuator
HV033_RS21755	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HV033_RS21760	ENOG4105VEJ	Heat shock protein
HV033_RS21765	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HV033_RS21770	ENOG4108MAJ	Membrane
HV033_RS21775	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HV033_RS21780	ENOG4105E0F	Histidine kinase
HV033_RS21790	ENOG4108RRZ	Transcription elongation factor GreB
HV033_RS21795	ENOG4105BZM	domain protein
HV033_RS21800	ENOG4105XFK	Ferrous iron transport protein A
HV033_RS21810	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HV033_RS21815	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HV033_RS21820	ENOG4105MJ2	Competence protein
HV033_RS21825	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HV033_RS21830	ENOG4105C6Z	Gluconate
HV033_RS21835	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HV033_RS21840	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HV033_RS21845	ENOG41061ZR	Transcriptional regulator
HV033_RS21850	ENOG4105E98	transcriptional regulator DeoR family
HV033_RS21855	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HV033_RS21860	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HV033_RS21865	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HV033_RS21870	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HV033_RS21875	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HV033_RS21880	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HV033_RS21885	ENOG4108ESZ	Glycogen debranching enzyme
HV033_RS21890	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HV033_RS21895	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HV033_RS21900	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HV033_RS21905	ENOG4105C6Z	Gluconate
HV033_RS21910	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HV033_RS21915	ENOG4105DIQ	Transcriptional regulator
HV033_RS21920	ENOG4105C2I	pirin domain protein
HV033_RS21925	ENOG4105D9R	oxidoreductase
HV033_RS21930	ENOG4105WCN	acetyltransferase
HV033_RS21935	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HV033_RS21940	ENOG4105WC8	Conserved Protein
HV033_RS21945	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HV033_RS21960	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HV033_RS21965	ENOG4105BZ7	extracellular solute-binding protein family 1
HV033_RS21970	ENOG4108IV0	ABC, transporter
HV033_RS21975	ENOG4105C0Z	ABC transporter
HV033_RS21980	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HV033_RS21985	ENOG4105C32	Amino acid ABC transporter (Permease)
HV033_RS21990	ENOG4105CP9	extracellular ligand-binding receptor
HV033_RS21995	ENOG4105U59	-acetyltransferase
HV033_RS22000	ENOG4105CP9	extracellular ligand-binding receptor
HV033_RS22005	ENOG4108JPW	Aminotransferase
HV033_RS22010	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HV033_RS22015	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HV033_RS22020	ENOG4105CAK	Cell division ATP-binding protein ftsE
HV033_RS22025	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HV033_RS22030	ENOG4106H78	methyltransferase
HV033_RS22035	ENOG4105MG3	Membrane
HV033_RS22045	ENOG4107FS9	Membrane
HV033_RS22050	ENOG4105C59	p-type ATPase
HV033_RS22055	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HV033_RS22065	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HV033_RS22070	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HV033_RS22075	ENOG4105EX9	Membrane
HV033_RS22080	ENOG4108W1V	Lipoprotein
HV033_RS22085	ENOG4105DSF	transport protein
HV033_RS22125	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HV033_RS22150	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HV033_RS22160	ENOG4105C2D	reductase
HV033_RS22165	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HV033_RS22170	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
HV033_RS22175	ENOG4105PY6	Phenolic acid decarboxylase
HV033_RS22180	ENOG4105ETT	transcriptional Regulator, LysR family
HV033_RS22185	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HV033_RS22205	ENOG4107258	Transcriptional regulator
HV033_RS22210	ENOG4105JSC	dimethylmenaquinone methyltransferase
HV033_RS22225	ENOG4105GR3	Histidine kinase
HV033_RS22230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HV033_RS22235	ENOG4108PG2	copper resistance
HV033_RS22240	ENOG4105JDN	Copper resistance protein
HV033_RS22245	ENOG4105VR0	copper resistance
HV033_RS22250	ENOG4105E3B	Multicopper oxidase
HV033_RS22260	ENOG4105DR5	peptidase
HV033_RS22290	ENOG410624V	efflux system protein
HV033_RS22355	ENOG4105CBX	hi0933 family
HV033_RS22360	ENOG4105CJ3	phosphate transporter
HV033_RS22365	ENOG4108V6B	universal stress protein B
HV033_RS22375	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HV033_RS22380	ENOG4105DGW	oligopeptidase A
HV033_RS22385	ENOG4105D6S	protein involved in catabolism of external DNA
HV033_RS22390	ENOG4105DC8	reductase
HV033_RS22415	ENOG4106S2D	Transcriptional regulator
HV033_RS22420	ENOG4105CHR	reductase
HV033_RS22425	ENOG4105CBN	LysR family transcriptional regulator
HV033_RS22430	ENOG4107H3J	ribonuclease
HV033_RS22435	ENOG4105CSH	Transporter
HV033_RS22440	ENOG41066T0	asmA family
HV033_RS22445	ENOG4105CMB	EAL domain-containing protein
HV033_RS22455	ENOG4105CS0	peptidase
HV033_RS22460	ENOG4105CK2	sodium dicarboxylate symporter
HV033_RS22465	ENOG4105BZU	Histidine kinase
HV033_RS22470	ENOG4105EJG	cellulose synthase
HV033_RS22475	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HV033_RS22480	ENOG4107EEX	Cellulose synthase regulator protein
HV033_RS22490	ENOG4105UTS	cellulose synthase operon protein YhjQ
HV033_RS22495	ENOG410661M	cytoplasmic protein
HV033_RS22500	ENOG4105U74	cellulose biosynthesis protein BcsE
HV033_RS22505	ENOG410675P	Celllulose biosynthesis operon protein BcsF YhjT
HV033_RS22510	ENOG4105D1V	cellulose synthase operon protein YhjU
HV033_RS22515	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HV033_RS22520	ENOG4105D4A	Cell wall formation (By similarity)
HV033_RS22550	ENOG4108RR8	protoporphyrinogen oxidase
HV033_RS22555	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HV033_RS22560	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HV033_RS22565	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HV033_RS22570	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HV033_RS22575	ENOG4105CHU	acetyl-coa acetyltransferase
HV033_RS22580	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HV033_RS22585	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HV033_RS22595	ENOG4105MEV	Acyl-transferase
HV033_RS22600	ENOG4105CMG	Carbohydrate kinase
HV033_RS22605	ENOG4105C93	Xylose Isomerase
HV033_RS22610	ENOG4105DFW	ABC transporter
HV033_RS22615	ENOG4105C2J	ABC transporter
HV033_RS22620	ENOG4108HWW	ABC transporter
HV033_RS22625	ENOG4105T16	Transcriptional regulator (AraC family)
HV033_RS22630	ENOG4108UR8	BAX protein
HV033_RS22635	ENOG4107T9C	Alpha amylase catalytic region
HV033_RS22640	ENOG4105JKW	Valine--pyruvate aminotransferase
HV033_RS22645	ENOG4108XIB	electron transport protein ysaA
HV033_RS22650	ENOG4105J4Q	Transcriptional regulator
HV033_RS22660	ENOG4108R66	Conserved Protein
HV033_RS22665	ENOG4108M5W	
HV033_RS22670	ENOG4105DJB	Major Facilitator Superfamily
HV033_RS22675	ENOG4105CMG	Carbohydrate kinase
HV033_RS22680	ENOG4105H6Q	decarboxylase
HV033_RS22685	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HV033_RS22690	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HV033_RS22720	ENOG4105C26	Dehydrogenase
HV033_RS22725	ENOG41066F8	ROK family
HV033_RS22730	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HV033_RS22740	ENOG4108U78	Glutathione S-transferase
HV033_RS22745	ENOG4105CTS	PTS system mannitol-specific
HV033_RS22755	ENOG4105E61	Mannitol repressor protein
HV033_RS22760	ENOG4108YYI	Protein of unknown function (DUF2810)
HV033_RS22770	ENOG4105CW0	outer membrane usher protein
HV033_RS22775	ENOG4108VCD	Chaperone
HV033_RS22780	ENOG4108S54	Fimbrial protein
HV033_RS22785	ENOG4105DAA	L-lactate
HV033_RS22790	ENOG41073TP	transcriptional regulator
HV033_RS22795	ENOG4105DMF	Dehydrogenase
HV033_RS22800	ENOG4105D2S	major facilitator superfamily
HV033_RS22805	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HV033_RS22815	ENOG4105EMY	transcriptional regulator
HV033_RS22820	ENOG4105C7B	Threonine dehydratase
HV033_RS22830	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HV033_RS22835	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HV033_RS22850	ENOG4105C0P	Mg chelatase subunit ChlI
HV033_RS22855	ENOG4108WFC	UPF0438 protein yifE
HV033_RS22905	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HV033_RS22910	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HV033_RS22915	ENOG4108Y73	Membrane
HV033_RS22920	ENOG4105EJ2	Transcriptional regulator
HV033_RS22930	ENOG4105C5Q	Transcriptional regulator
HV033_RS22935	ENOG4105CH7	arginosuccinase
HV033_RS22940	ENOG4105CAS	nag kinase
HV033_RS22945	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HV033_RS22950	ENOG4105CWC	Acetylornithine deacetylase
HV033_RS22955	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HV033_RS22960	ENOG4106R3P	AraC family transcriptional regulator
HV033_RS22965	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HV033_RS22970	ENOG4105DCT	glycerol dehydrogenase
HV033_RS22975	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HV033_RS22980	ENOG4105SYT	Methylenetetrahydrofolate reductase
HV033_RS22985	ENOG4105CFH	Aspartokinase
HV033_RS22990	ENOG4105C28	cystathionine
HV033_RS22995	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HV033_RS23000	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HV033_RS23005	ENOG4105C25	Primosomal protein n'
HV033_RS23010	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS23015	ENOG41063M6	Cell Division Protein
HV033_RS23020	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HV033_RS23025	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HV033_RS23030	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HV033_RS23035	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HV033_RS23040	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HV033_RS23045	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HV033_RS23050	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HV033_RS23055	ENOG4105CBT	Fructose-1,6-bisphosphatase
HV033_RS23060	ENOG4105DP0	ferredoxin-NADP reductase
HV033_RS23065	ENOG4108VTS	Membrane
HV033_RS23070	ENOG4105EBK	exported protein
HV033_RS23075	ENOG4105CP7	Triose-phosphate isomerase
HV033_RS23085	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HV033_RS23090	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HV033_RS23095	ENOG4105CTQ	phosphohexokinase
HV033_RS23100	ENOG41076HS	cation diffusion facilitator family transporter
HV033_RS23105	ENOG4105FMW	periplasmic
HV033_RS23110	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HV033_RS23115	ENOG4105E0F	Histidine kinase
HV033_RS23120	ENOG4108RPX	mosc domain containing protein
HV033_RS23125	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HV033_RS23130	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
HV033_RS23135	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HV033_RS23140	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HV033_RS23145	ENOG4105DET	Rhamnulokinase
HV033_RS23150	ENOG4105DKG	l-rhamnose isomerase
HV033_RS23155	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
HV033_RS23160	ENOG4105D4B	ABC, transporter
HV033_RS23165	ENOG4105C2J	ABC transporter
HV033_RS23170	ENOG4105CNN	ABC, transporter
HV033_RS23175	ENOG4105F5R	ABC transporter
HV033_RS23180	ENOG4105C0A	alcohol dehydrogenase
HV033_RS23185	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HV033_RS23190	ENOG4108VEV	chaperone
HV033_RS23200	ENOG4105CW0	outer membrane usher protein
HV033_RS23205	ENOG4108NAE	Fimbrial chaperone protein
HV033_RS23220	ENOG4108UMN	azlc family
HV033_RS23245	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HV033_RS23250	ENOG4108MG3	formate dehydrogenase
HV033_RS23255	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HV033_RS23265	ENOG41068KX	affects formate dehydrogenase-N
HV033_RS23275	ENOG4105SUU	thioesterase domain
HV033_RS23280	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HV033_RS23285	ENOG4107S2Z	UPF0761 membrane protein
HV033_RS23290	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HV033_RS23295	ENOG4105E98	transcriptional regulator DeoR family
HV033_RS23300	ENOG4108MGF	sugar kinase
HV033_RS23305	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HV033_RS23310	ENOG4105D2M	Aldolase
HV033_RS23315	ENOG4107QKS	N-acylglucosamine 2-epimerase
HV033_RS23320	ENOG4105CJQ	hydrolase, family 31
HV033_RS23325	ENOG4105CT4	transporter
HV033_RS23330	ENOG4105CT4	transporter
HV033_RS23335	ENOG4108KUC	Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is
HV033_RS23340	ENOG4105CI3	gtp-binding protein typa
HV033_RS23345	ENOG4105C5F	glutamine synthetase
HV033_RS23350	ENOG4105CUX	Signal transduction histidine kinase
HV033_RS23355	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HV033_RS23360	ENOG4106FIY	
HV033_RS23365	ENOG4105D4P	Coproporphyrinogen iii oxidase
HV033_RS23370	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HV033_RS23375	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HV033_RS23380	ENOG4105C2M	dna polymerase I
HV033_RS23385	ENOG4106HNH	Acyl-transferase
HV033_RS23390	ENOG4108Z33	Thiol disulfide Interchange Protein
HV033_RS23395	ENOG4105E27	serine threonine protein kinase
HV033_RS23400	ENOG4105PC1	Conserved Protein
HV033_RS23405	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HV033_RS23410	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HV033_RS23435	ENOG4107EJG	GntR family transcriptional regulator
HV033_RS23440	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HV033_RS23445	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS23450	ENOG4108RVA	ribokinase
HV033_RS23455	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HV033_RS23460	ENOG4105CNN	ABC, transporter
HV033_RS23465	ENOG4105C2J	ABC transporter
HV033_RS23470	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HV033_RS23475	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HV033_RS23485	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HV033_RS23490	ENOG4105CU9	asparagine synthetase A
HV033_RS23495	ENOG4108VVK	transcriptional Regulator, AsnC
HV033_RS23500	ENOG4105QTB	Flavodoxin
HV033_RS23505	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HV033_RS23510	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HV033_RS23515	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HV033_RS23520	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HV033_RS23530	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HV033_RS23535	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HV033_RS23540	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HV033_RS23550	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HV033_RS23555	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HV033_RS23560	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HV033_RS23565	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HV033_RS23570	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HV033_RS23575	ENOG4105C8U	phosphate abc transporter
HV033_RS23580	ENOG4105E2Z	phosphate ABC transporter (Permease
HV033_RS23585	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HV033_RS23595	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HV033_RS23600	ENOG4105C7N	Xanthine uracil vitamin C permease
HV033_RS23605	ENOG4108YYH	Nadph-dependent fmn reductase
HV033_RS23610	ENOG4105E8Q	phosphopantetheinyl transferase
HV033_RS23615	ENOG4105G2Y	Transcriptional regulator
HV033_RS23620	ENOG4105CNH	Multidrug resistance protein MdtL
HV033_RS23625	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HV033_RS23630	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HV033_RS23640	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HV033_RS23645	ENOG4105VG0	50S ribosomal protein l34
HV033_RS23690	ENOG4105GR3	Histidine kinase
HV033_RS23695	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HV033_RS23700	ENOG4108PG2	copper resistance
HV033_RS23705	ENOG4105JDN	Copper resistance protein
HV033_RS23710	ENOG4105VR0	copper resistance
HV033_RS23715	ENOG4105E3B	Multicopper oxidase
HV033_RS23725	ENOG4105DR5	peptidase
HV033_RS23750	ENOG4108YXQ	IS66 Orf2 family protein
HV033_RS23755	ENOG4105E5H	Transposase
HV033_RS23775	ENOG410624V	efflux system protein
HV033_RS23815	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HV033_RS23820	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HV033_RS23985	ENOG4105FEQ	ParB domain protein nuclease
HV033_RS24020	ENOG4108YDI	single-species biofilm formation on inanimate substrate
HV033_RS24025	ENOG41061MD	high-affinity nickel-transporter
HV033_RS24035	ENOG4107Y80	Major Facilitator superfamily
HV033_RS24090	ENOG4105K4U	addiction module toxin, RelE StbE family
HV033_RS24095	ENOG41074AV	Hok/gef family
HV033_RS24175	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS24195	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HV033_RS24205	ENOG4105ETE	Transcriptional regulator (LacI family
HV033_RS24210	ENOG4105CIS	alcohol dehydrogenase
HV033_RS24220	ENOG4105EQR	Transposase IS116 IS110 IS902
HV033_RS24235	ENOG4108YXQ	IS66 Orf2 family protein
HV033_RS24240	ENOG4105E0A	ABC, transporter
HV033_RS24245	ENOG4108IHU	transport system permease protein
HV033_RS24250	ENOG4105DQ5	transport system permease protein
HV033_RS24255	ENOG4108HUF	Transporter
HV033_RS24260	ENOG4105GAV	receptor
HV033_RS24265	ENOG4108S3W	Anti-feci sigma factor, fecr
HV033_RS24270	ENOG4108SF5	RNA Polymerase
HV033_RS24315	ENOG4105D0M	Protease HtpX homolog
HV033_RS24375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HV033_RS24380	ENOG4105VN1	Heat shock protein
HV033_RS24505	ENOG4105M5B	(LipO)protein