locus-tag	class	description
LI65_RS00175	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI65_RS00335	COG0697	spore germination
LI65_RS00350	COG4580	involved in the transport of maltose and maltodextrins
LI65_RS00425	COG0823	Involved in the tonB-independent uptake of proteins
LI65_RS00470	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI65_RS00620	COG2723	6-phospho-beta-galactosidase activity
LI65_RS00680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS00920	COG0592	DNA-directed DNA polymerase activity
LI65_RS00925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LI65_RS00935	COG0583	DNA-binding transcription factor activity
LI65_RS00940	COG0604	alcohol dehydrogenase
LI65_RS00940	COG3321	synthase
LI65_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS00945	COG0561	phosphatase activity
LI65_RS00950	COG2186	Transcriptional regulator
LI65_RS00955	COG3734	2-keto-3-deoxy-galactonokinase
LI65_RS00960	COG0800	Aldolase
LI65_RS00965	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS00970	COG2271	Major facilitator Superfamily
LI65_RS00975	COG0823	Involved in the tonB-independent uptake of proteins
LI65_RS00980	COG5645	(Lipo)protein
LI65_RS00990	COG0071	Belongs to the small heat shock protein (HSP20) family
LI65_RS00995	COG2985	domain, Protein
LI65_RS01000	COG2188	Transcriptional regulator
LI65_RS01015	COG2207	Transcriptional regulator
LI65_RS01020	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI65_RS01025	COG3119	arylsulfatase activity
LI65_RS01030	COG2149	membrane
LI65_RS01040	COG0641	radical SAM
LI65_RS01050	COG2610	gluconate transmembrane transporter activity
LI65_RS01055	COG0583	DNA-binding transcription factor activity
LI65_RS01060	COG2814	Major facilitator Superfamily
LI65_RS01095	COG0028	Belongs to the TPP enzyme family
LI65_RS01100	COG0440	acetolactate synthase activity
LI65_RS01105	COG2197	response regulator
LI65_RS01125	COG0596	Alpha beta hydrolase
LI65_RS01130	COG0583	DNA-binding transcription factor activity
LI65_RS01150	COG0697	spore germination
LI65_RS01155	COG4580	involved in the transport of maltose and maltodextrins
LI65_RS01160	COG1447	Phosphotransferase system cellobiose-specific component IIA
LI65_RS01165	COG2723	6-phospho-beta-galactosidase activity
LI65_RS01170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS01170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS01180	COG1609	Transcriptional regulator
LI65_RS01190	COG2814	Major facilitator Superfamily
LI65_RS01200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS01205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS01215	COG0454	-acetyltransferase
LI65_RS01220	COG1309	transcriptional regulator
LI65_RS01230	COG1464	Belongs to the NlpA lipoprotein family
LI65_RS01255	COG3188	usher protein
LI65_RS01260	COG3121	Chaperone
LI65_RS01290	COG3188	usher protein
LI65_RS01315	COG2274	protein secretion by the type I secretion system
LI65_RS01330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LI65_RS01345	COG3272	Protein of unknown function (DUF1722)
LI65_RS01350	COG2351	hydroxyisourate hydrolase activity
LI65_RS01380	COG3121	Chaperone
LI65_RS01410	COG0519	Catalyzes the synthesis of GMP from XMP
LI65_RS01455	COG2211	Major facilitator Superfamily
LI65_RS01460	COG1501	Belongs to the glycosyl hydrolase 31 family
LI65_RS01465	COG2982	Protein involved in outer membrane biogenesis
LI65_RS01470	COG2233	PERMEase
LI65_RS01475	COG0786	glutamate:sodium symporter activity
LI65_RS01480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LI65_RS01485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI65_RS01490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LI65_RS01505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LI65_RS01525	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS01530	COG1596	polysaccharide export
LI65_RS01535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LI65_RS01540	COG0489	protein tyrosine kinase activity
LI65_RS01540	COG3206	protein involved in exopolysaccharide biosynthesis
LI65_RS01545	COG2860	membrane
LI65_RS01550	COG1561	YicC-like family, N-terminal region
LI65_RS01560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LI65_RS01575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LI65_RS01580	COG2003	Belongs to the UPF0758 family
LI65_RS01585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LI65_RS01590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LI65_RS01595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LI65_RS01600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LI65_RS01610	COG1519	Transferase
LI65_RS01615	COG1216	Glycosyl transferase, family 2
LI65_RS01620	COG0438	transferase activity, transferring glycosyl groups
LI65_RS01630	COG0859	PFAM glycosyl transferase family 9
LI65_RS01655	COG0859	PFAM glycosyl transferase family 9
LI65_RS01660	COG0859	PFAM glycosyl transferase family 9
LI65_RS01675	COG1063	alcohol dehydrogenase
LI65_RS01685	COG0438	transferase activity, transferring glycosyl groups
LI65_RS01690	COG0463	Glycosyl transferase, family 2
LI65_RS01695	COG2861	carbohydrate metabolic process
LI65_RS01700	COG4942	peptidase
LI65_RS01705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LI65_RS01710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LI65_RS01715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LI65_RS01720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LI65_RS01725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LI65_RS01735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI65_RS01745	COG0248	Ppx GppA phosphatase
LI65_RS01755	COG3118	belongs to the thioredoxin family
LI65_RS01760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LI65_RS01765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LI65_RS01775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LI65_RS01780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LI65_RS01785	COG0456	acetyltransferase
LI65_RS01790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LI65_RS01795	COG2244	polysaccharide biosynthetic process
LI65_RS01810	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LI65_RS01840	COG3071	HemY protein
LI65_RS01845	COG2959	enzyme of heme biosynthesis
LI65_RS01855	COG0181	hydroxymethylbilane synthase activity
LI65_RS01870	COG5567	small periplasmic lipoprotein
LI65_RS01890	COG1011	Hydrolase
LI65_RS01895	COG0210	DNA helicase
LI65_RS01915	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LI65_RS01925	COG1280	lysine exporter protein (LysE YggA)
LI65_RS01930	COG1280	lysine exporter protein (LysE YggA)
LI65_RS01935	COG2267	carboxylic ester hydrolase activity
LI65_RS01940	COG0561	phosphatase activity
LI65_RS01945	COG0697	spore germination
LI65_RS01950	COG0583	DNA-binding transcription factor activity
LI65_RS01960	COG0412	Dienelactone hydrolase
LI65_RS01970	COG1322	Protein conserved in bacteria
LI65_RS01975	COG2226	methyltransferase
LI65_RS01980	COG3165	ubiquinone biosynthetic process from chorismate
LI65_RS01985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LI65_RS02000	COG0805	protein transport
LI65_RS02005	COG0084	hydrolase, TatD family'
LI65_RS02015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LI65_RS02025	COG0488	(ABC) transporter
LI65_RS02030	COG2944	sequence-specific DNA binding
LI65_RS02045	COG1278	Cold shock
LI65_RS02050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LI65_RS02060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS02070	COG1609	Transcriptional regulator
LI65_RS02075	COG2885	chlorophyll binding
LI65_RS02080	COG0243	molybdopterin cofactor binding
LI65_RS02085	COG0456	acetyltransferase
LI65_RS02090	COG2818	Glycosylase
LI65_RS02095	COG5571	outer membrane autotransporter
LI65_RS02100	COG2223	nitrite transmembrane transporter activity
LI65_RS02115	COG0747	negative chemotaxis
LI65_RS02120	COG0601	transmembrane transport
LI65_RS02125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI65_RS02130	COG0444	Belongs to the ABC transporter superfamily
LI65_RS02135	COG4608	Belongs to the ABC transporter superfamily
LI65_RS02140	COG1072	(Pantothenic acid kinase))
LI65_RS02175	COG0250	Participates in transcription elongation, termination and antitermination
LI65_RS02220	COG3706	GGDEF domain
LI65_RS02230	COG2022	thiamine diphosphate biosynthetic process
LI65_RS02235	COG2104	thiamine diphosphate biosynthetic process
LI65_RS02240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LI65_RS02255	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LI65_RS02265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LI65_RS02270	COG1515	deoxyribonuclease V activity
LI65_RS02275	COG3068	Protein conserved in bacteria
LI65_RS02290	COG0151	Belongs to the GarS family
LI65_RS02325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LI65_RS02335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LI65_RS02355	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LI65_RS02360	COG3657	addiction module killer protein
LI65_RS02365	COG1187	pseudouridine synthase activity
LI65_RS02380	COG0527	aspartate kinase activity
LI65_RS02405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS02410	COG3223	Belongs to the PsiE family
LI65_RS02435	COG4580	involved in the transport of maltose and maltodextrins
LI65_RS02445	COG3161	chorismate lyase activity
LI65_RS02455	COG2937	Belongs to the GPAT DAPAT family
LI65_RS02460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LI65_RS02465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LI65_RS02470	COG0534	Mate efflux family protein
LI65_RS02475	COG3237	CsbD-like
LI65_RS02480	COG0735	belongs to the Fur family
LI65_RS02495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LI65_RS02505	COG0604	alcohol dehydrogenase
LI65_RS02510	COG0305	Participates in initiation and elongation during chromosome replication
LI65_RS02520	COG1448	Aminotransferase
LI65_RS02525	COG3700	Belongs to the class B bacterial acid phosphatase family
LI65_RS02535	COG2315	Protein conserved in bacteria
LI65_RS02545	COG0629	single-stranded DNA binding
LI65_RS02560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LI65_RS02570	COG0789	Transcriptional regulator
LI65_RS02575	COG0625	glutathione transferase activity
LI65_RS02580	COG2252	PERMEase
LI65_RS02585	COG0025	NhaP-type Na H and K H
LI65_RS02590	COG0583	DNA-binding transcription factor activity
LI65_RS02600	COG1346	cytolysis
LI65_RS02605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI65_RS02610	COG3162	membrane
LI65_RS02620	COG1301	dicarboxylic acid transport
LI65_RS02625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LI65_RS02635	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS02640	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS02655	COG0191	fructose-bisphosphate aldolase activity
LI65_RS02670	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS02675	COG1129	ABC transporter
LI65_RS02680	COG0784	Response regulator, receiver
LI65_RS02680	COG4191	Histidine kinase
LI65_RS02685	COG1940	carbohydrate kinase activity
LI65_RS02690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LI65_RS02695	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS02700	COG1129	ABC transporter
LI65_RS02705	COG1879	ABC-type sugar transport system periplasmic component
LI65_RS02710	COG1737	Transcriptional regulator
LI65_RS02715	COG0698	ribose 5-phosphate isomerase
LI65_RS02725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LI65_RS02730	COG0456	acetyltransferase
LI65_RS02735	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LI65_RS02740	COG3454	Phosphonate metabolism
LI65_RS02745	COG4778	phosphonate C-P lyase system protein PhnL
LI65_RS02750	COG4107	phosphonate C-P lyase system protein PhnK
LI65_RS02755	COG3627	carbon phosphorus lyase activity
LI65_RS02760	COG3626	phosphonate metabolism
LI65_RS02765	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LI65_RS02770	COG3624	Phosphonate C-P lyase system protein PhnG
LI65_RS02775	COG2188	Transcriptional regulator
LI65_RS02780	COG3639	organic phosphonate transmembrane transporter activity
LI65_RS02785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LI65_RS02795	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LI65_RS02800	COG2824	Alkylphosphonate utilization operon protein PhnA
LI65_RS02805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LI65_RS02825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LI65_RS02855	COG3647	Membrane
LI65_RS02875	COG1309	transcriptional regulator
LI65_RS02890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LI65_RS02895	COG1027	Aspartate ammonia-lyase
LI65_RS02900	COG3030	protein affecting phage T7 exclusion by the F plasmid
LI65_RS02905	COG0531	amino acid
LI65_RS02915	COG0459	protein refolding
LI65_RS02920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LI65_RS02925	COG0700	Nucleoside recognition
LI65_RS02930	COG3366	ferrous iron transmembrane transporter activity
LI65_RS02955	COG5510	response to toxic substance
LI65_RS02980	COG0583	DNA-binding transcription factor activity
LI65_RS02990	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LI65_RS02995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LI65_RS03000	COG1053	succinate dehydrogenase
LI65_RS03005	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LI65_RS03015	COG3264	Mechanosensitive ion channel
LI65_RS03015	COG1511	domain protein
LI65_RS03050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LI65_RS03055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LI65_RS03055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LI65_RS03060	COG0802	atpase or kinase
LI65_RS03070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LI65_RS03075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LI65_RS03080	COG1923	regulation of RNA biosynthetic process
LI65_RS03085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LI65_RS03090	COG0330	HflC and HflK could
LI65_RS03095	COG0330	HflC and HflK could
LI65_RS03100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LI65_RS03110	COG1959	2 iron, 2 sulfur cluster binding
LI65_RS03115	COG0557	exoribonuclease II activity
LI65_RS03120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI65_RS03125	COG0477	Major facilitator Superfamily
LI65_RS03130	COG1960	acyl-CoA dehydrogenase activity
LI65_RS03145	COG3650	response to hydrogen peroxide
LI65_RS03150	COG1073	alpha beta
LI65_RS03165	COG3037	sugar-specific permease SgaT UlaA
LI65_RS03205	COG2965	DNA replication, synthesis of RNA primer
LI65_RS03210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LI65_RS03215	COG0359	binds to the 23S rRNA
LI65_RS03220	COG0697	spore germination
LI65_RS03225	COG3061	Opacity-associated protein A
LI65_RS03230	COG0545	Peptidyl-prolyl cis-trans isomerase
LI65_RS03235	COG1113	amino acid transport
LI65_RS03245	COG0840	transmembrane signaling receptor activity
LI65_RS03250	COG0697	spore germination
LI65_RS03260	COG0702	epimerase
LI65_RS03265	COG1733	regulation of RNA biosynthetic process
LI65_RS03275	COG1218	3'(2'),5'-bisphosphate nucleotidase
LI65_RS03280	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LI65_RS03290	COG1253	flavin adenine dinucleotide binding
LI65_RS03295	COG2211	Major facilitator Superfamily
LI65_RS03300	COG0673	inositol 2-dehydrogenase activity
LI65_RS03310	COG0673	inositol 2-dehydrogenase activity
LI65_RS03315	COG0673	inositol 2-dehydrogenase activity
LI65_RS03320	COG1609	Transcriptional regulator
LI65_RS03325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LI65_RS03330	COG0729	surface antigen
LI65_RS03335	COG2911	Protein conserved in bacteria
LI65_RS03340	COG2105	PFAM AIG2 family protein
LI65_RS03350	COG1879	ABC-type sugar transport system periplasmic component
LI65_RS03355	COG1129	ABC transporter
LI65_RS03360	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS03365	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS03370	COG0840	transmembrane signaling receptor activity
LI65_RS03380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LI65_RS03385	COG3028	Belongs to the UPF0307 family
LI65_RS03390	COG0312	modulator of DNA gyrase
LI65_RS03430	COG3964	amidohydrolase
LI65_RS03450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS03450	COG3711	transcriptional antiterminator
LI65_RS03455	COG0602	queuosine metabolic process
LI65_RS03465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS03465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS03465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS03470	COG0383	alpha-mannosidase activity
LI65_RS03490	COG0366	Alpha amylase catalytic
LI65_RS03495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS03495	COG1263	PTS System
LI65_RS03500	COG1609	Transcriptional regulator
LI65_RS03510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LI65_RS03515	COG3397	chitin binding
LI65_RS03520	COG0251	oxidation-reduction process
LI65_RS03530	COG0540	Belongs to the ATCase OTCase family
LI65_RS03535	COG1438	arginine binding
LI65_RS03540	COG1288	antiporter activity
LI65_RS03555	COG2235	arginine
LI65_RS03560	COG2731	YhcH YjgK YiaL family protein
LI65_RS03565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LI65_RS03570	COG0129	dihydroxy-acid dehydratase activity
LI65_RS03575	COG2211	Major facilitator Superfamily
LI65_RS03580	COG3507	Belongs to the glycosyl hydrolase 43 family
LI65_RS03585	COG1414	Transcriptional regulator
LI65_RS03590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LI65_RS03725	COG1609	Transcriptional regulator
LI65_RS03735	COG2211	Major facilitator Superfamily
LI65_RS03760	COG1335	isochorismatase
LI65_RS03775	COG2204	response regulator
LI65_RS03780	COG4191	Histidine kinase
LI65_RS03785	COG4566	intracellular signal transduction
LI65_RS03790	COG0346	lactoylglutathione lyase activity
LI65_RS03795	COG0740	serine-type endopeptidase activity
LI65_RS03800	COG2850	peptidyl-arginine hydroxylation
LI65_RS03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI65_RS03830	COG5457	Domain of unknown function (DUF1127)
LI65_RS03840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI65_RS03850	COG0640	Transcriptional regulator
LI65_RS03860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS03870	COG2733	membrane
LI65_RS03885	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS03900	COG0523	cobalamin synthesis protein
LI65_RS03905	COG2879	small protein
LI65_RS03910	COG1966	Carbon starvation protein
LI65_RS03915	COG1349	DNA-binding transcription factor activity
LI65_RS03920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI65_RS03925	COG2368	4-hydroxyphenylacetate
LI65_RS03945	COG3971	2-oxopent-4-enoate hydratase activity
LI65_RS03955	COG3384	dioxygenase
LI65_RS03960	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS03965	COG0179	Fumarylacetoacetate (FAA) hydrolase
LI65_RS03970	COG1846	Transcriptional regulator
LI65_RS03975	COG0840	transmembrane signaling receptor activity
LI65_RS03995	COG1484	DNA-dependent DNA replication
LI65_RS04005	COG1764	response to oxidative stress
LI65_RS04010	COG1846	Transcriptional regulator
LI65_RS04015	COG3610	response to peptide
LI65_RS04020	COG2966	Psort location CytoplasmicMembrane, score
LI65_RS04025	COG2197	response regulator
LI65_RS04030	COG2197	response regulator
LI65_RS04035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI65_RS04040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS04040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS04045	COG4114	ferric iron reductase
LI65_RS04075	COG2813	Specifically methylates the guanine in position
LI65_RS04080	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LI65_RS04085	COG0456	acetyltransferase
LI65_RS04090	COG1011	Hydrolase
LI65_RS04095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LI65_RS04100	COG2823	Periplasmic or secreted lipoprotein
LI65_RS04105	COG5487	UPF0391 membrane protein
LI65_RS04110	COG4667	esterase of the alpha-beta hydrolase superfamily
LI65_RS04115	COG0084	hydrolase, TatD family'
LI65_RS04120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI65_RS04125	COG1328	CTP reductase activity
LI65_RS04135	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LI65_RS04155	COG3726	membrane protein affecting hemolysin expression
LI65_RS04160	COG0560	Phosphoserine phosphatase
LI65_RS04185	COG0488	(ABC) transporter
LI65_RS04190	COG0741	lytic transglycosylase activity
LI65_RS04195	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LI65_RS04200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LI65_RS04205	COG0406	alpha-ribazole phosphatase activity
LI65_RS04210	COG2207	Transcriptional regulator
LI65_RS04210	COG3708	Transcriptional regulator
LI65_RS04215	COG3045	CreA protein
LI65_RS04220	COG0745	RESPONSE REGULATOR receiver
LI65_RS04225	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LI65_RS04230	COG0527	aspartate kinase activity
LI65_RS04230	COG0460	homoserine dehydrogenase
LI65_RS04240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LI65_RS04255	COG1115	amino acid carrier protein
LI65_RS04265	COG0521	Mo-molybdopterin cofactor biosynthetic process
LI65_RS04270	COG0477	Major facilitator Superfamily
LI65_RS04275	COG1584	GPR1 FUN34 yaaH family protein
LI65_RS04285	COG0443	Heat shock 70 kDa protein
LI65_RS04295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LI65_RS04300	COG0583	DNA-binding transcription factor activity
LI65_RS04305	COG0268	Binds directly to 16S ribosomal RNA
LI65_RS04310	COG0196	riboflavin kinase activity
LI65_RS04325	COG1047	Peptidyl-prolyl cis-trans
LI65_RS04345	COG3716	PTS system mannose fructose sorbose family IID component
LI65_RS04350	COG3715	PTS system
LI65_RS04355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS04370	COG1609	Transcriptional regulator
LI65_RS04380	COG0505	Belongs to the CarA family
LI65_RS04400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI65_RS04400	COG0475	glutathione-regulated potassium exporter activity
LI65_RS04410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LI65_RS04415	COG2967	ApaG domain
LI65_RS04425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LI65_RS04430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI65_RS04435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI65_RS04440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LI65_RS04445	COG0564	pseudouridine synthase activity
LI65_RS04450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LI65_RS04455	COG0417	DNA replication proofreading
LI65_RS04460	COG0235	Class ii aldolase
LI65_RS04465	COG2160	L-arabinose isomerase activity
LI65_RS04470	COG1069	ribulokinase activity
LI65_RS04480	COG0586	Pfam SNARE associated Golgi protein
LI65_RS04490	COG1178	ABC-type Fe3 transport system permease component
LI65_RS04510	COG2814	Major facilitator Superfamily
LI65_RS04535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LI65_RS04545	COG0028	Belongs to the TPP enzyme family
LI65_RS04555	COG1609	Transcriptional regulator
LI65_RS04560	COG2001	Belongs to the MraZ family
LI65_RS04575	COG0768	penicillin binding
LI65_RS04580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LI65_RS04585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LI65_RS04590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LI65_RS04600	COG0772	Belongs to the SEDS family
LI65_RS04615	COG1181	Belongs to the D-alanine--D-alanine ligase family
LI65_RS04625	COG0849	cell division
LI65_RS04630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LI65_RS04635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LI65_RS04645	COG0653	protein targeting
LI65_RS04650	COG0494	nUDIX hydrolase
LI65_RS04655	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LI65_RS04660	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LI65_RS04670	COG0516	GMP reductase activity
LI65_RS04675	COG1459	type II secretion system
LI65_RS04680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LI65_RS04685	COG4969	Belongs to the N-Me-Phe pilin family
LI65_RS04695	COG3023	N-Acetylmuramoyl-L-alanine amidase
LI65_RS04700	COG3725	Membrane protein required for beta-lactamase induction
LI65_RS04705	COG3940	Belongs to the glycosyl hydrolase 43 family
LI65_RS04710	COG2211	Major facilitator Superfamily
LI65_RS04715	COG1113	amino acid transport
LI65_RS04725	COG2186	Transcriptional regulator
LI65_RS04730	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LI65_RS04735	COG0508	dehydrogenase complex catalyzes the overall conversion of
LI65_RS04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LI65_RS04750	COG3064	Membrane
LI65_RS04770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LI65_RS04785	COG4993	Dehydrogenase
LI65_RS04795	COG0288	reversible hydration of carbon dioxide
LI65_RS04800	COG1131	(ABC) transporter
LI65_RS04805	COG0842	Transport permease protein
LI65_RS04810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS04815	COG0726	polysaccharide deacetylase
LI65_RS04835	COG3539	Fimbrial protein
LI65_RS04840	COG3188	usher protein
LI65_RS04845	COG3121	Chaperone
LI65_RS04855	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LI65_RS04860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LI65_RS04870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LI65_RS04890	COG1489	DNA binding
LI65_RS04895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LI65_RS04900	COG1643	Atp-dependent helicase
LI65_RS04905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LI65_RS04915	COG3121	Chaperone
LI65_RS04920	COG3188	usher protein
LI65_RS04930	COG4774	siderophore transport
LI65_RS04935	COG1120	ATPase activity
LI65_RS04940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LI65_RS04945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS04950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LI65_RS04960	COG0316	Belongs to the HesB IscA family
LI65_RS04965	COG2860	membrane
LI65_RS04975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LI65_RS04980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LI65_RS04985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LI65_RS04990	COG3835	regulator
LI65_RS05035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LI65_RS05045	COG0575	Belongs to the CDS family
LI65_RS05050	COG0750	zinc metalloprotease
LI65_RS05055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS05065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI65_RS05070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LI65_RS05075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI65_RS05080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI65_RS05085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LI65_RS05095	COG0825	malonyl-CoA metabolic process
LI65_RS05100	COG1982	Orn Lys Arg decarboxylase major
LI65_RS05105	COG0346	lactoylglutathione lyase activity
LI65_RS05110	COG0037	tRNA processing
LI65_RS05115	COG4568	rho-dependent transcription termination
LI65_RS05130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LI65_RS05135	COG3015	lipoprotein NlpE involved in copper resistance
LI65_RS05145	COG1720	tRNA m6t6A37 methyltransferase activity
LI65_RS05155	COG1464	Belongs to the NlpA lipoprotein family
LI65_RS05160	COG2011	ABC-type metal ion transport system permease component
LI65_RS05170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LI65_RS05210	COG0583	DNA-binding transcription factor activity
LI65_RS05215	COG2814	Major facilitator Superfamily
LI65_RS05220	COG3021	interspecies interaction between organisms
LI65_RS05225	COG2226	methyltransferase
LI65_RS05230	COG1388	LysM domain
LI65_RS05230	COG0741	lytic transglycosylase activity
LI65_RS05235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI65_RS05240	COG2226	methyltransferase
LI65_RS05265	COG0444	Belongs to the ABC transporter superfamily
LI65_RS05270	COG4608	Belongs to the ABC transporter superfamily
LI65_RS05275	COG0747	negative chemotaxis
LI65_RS05285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI65_RS05295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI65_RS05300	COG1960	acyl-CoA dehydrogenase activity
LI65_RS05310	COG0121	glutamine amidotransferase
LI65_RS05315	COG3034	peptidoglycan biosynthetic process
LI65_RS05330	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LI65_RS05335	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LI65_RS05350	COG2991	Protein conserved in bacteria
LI65_RS05355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LI65_RS05360	COG2195	Cleaves the N-terminal amino acid of tripeptides
LI65_RS05370	COG1073	alpha beta
LI65_RS05380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI65_RS05385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LI65_RS05390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LI65_RS05400	COG0582	viral genome integration into host DNA
LI65_RS05430	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LI65_RS05440	COG3300	MHYT domain
LI65_RS05440	COG5001	Diguanylate cyclase
LI65_RS05455	COG0628	permease
LI65_RS05460	COG0833	amino acid
LI65_RS05465	COG2040	homocysteine
LI65_RS05470	COG4521	taurine ABC transporter
LI65_RS05475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LI65_RS05480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LI65_RS05485	COG2175	clavaminate synthase activity
LI65_RS05495	COG0113	porphobilinogen synthase activity
LI65_RS05515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LI65_RS05520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LI65_RS05540	COG1181	Belongs to the D-alanine--D-alanine ligase family
LI65_RS05565	COG3706	GGDEF domain
LI65_RS05570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LI65_RS05575	COG1671	Belongs to the UPF0178 family
LI65_RS05580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI65_RS05590	COG4126	flavin adenine dinucleotide binding
LI65_RS05595	COG3123	guanosine phosphorylase activity
LI65_RS05605	COG1940	carbohydrate kinase activity
LI65_RS05610	COG0419	ATPase involved in DNA repair
LI65_RS05615	COG0420	3'-5' exonuclease activity
LI65_RS05625	COG5002	protein histidine kinase activity
LI65_RS05640	COG0366	Alpha amylase catalytic
LI65_RS05655	COG0450	alkyl hydroperoxide reductase
LI65_RS05660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LI65_RS05675	COG1862	Preprotein translocase
LI65_RS05680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LI65_RS05685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LI65_RS05700	COG3248	Nucleoside-binding outer membrane protein
LI65_RS05705	COG4238	major outer membrane lipoprotein
LI65_RS05710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LI65_RS05715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LI65_RS05715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LI65_RS05720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LI65_RS05725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LI65_RS05730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LI65_RS05735	COG0667	Aldo Keto reductase
LI65_RS05740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LI65_RS05745	COG0142	geranyltranstransferase activity
LI65_RS05760	COG2188	Transcriptional regulator
LI65_RS05770	COG1486	melibiose metabolic process
LI65_RS05775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS05780	COG0693	protein deglycase activity
LI65_RS05785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LI65_RS05795	COG2814	Major facilitator Superfamily
LI65_RS05800	COG0235	Class ii aldolase
LI65_RS05820	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS05825	COG1129	ABC transporter
LI65_RS05845	COG0109	protoheme IX farnesyltransferase activity
LI65_RS05850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LI65_RS05855	COG1845	cytochrome c oxidase, subunit III
LI65_RS05860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LI65_RS05865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LI65_RS05875	COG2223	nitrite transmembrane transporter activity
LI65_RS05880	COG3056	Lipoprotein
LI65_RS05885	COG0271	Belongs to the BolA IbaG family
LI65_RS05890	COG0544	peptidyl-prolyl cis-trans isomerase activity
LI65_RS05905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LI65_RS05910	COG0776	regulation of translation
LI65_RS05915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LI65_RS05920	COG1555	photosystem II stabilization
LI65_RS05925	COG0824	Thioesterase
LI65_RS05930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LI65_RS05935	COG4533	DNA binding
LI65_RS05940	COG0561	phosphatase activity
LI65_RS05950	COG1522	sequence-specific DNA binding
LI65_RS05955	COG1132	(ABC) transporter
LI65_RS05960	COG1132	(ABC) transporter
LI65_RS05965	COG0347	Belongs to the P(II) protein family
LI65_RS05970	COG0004	ammonium transporteR
LI65_RS05975	COG1946	Acyl-CoA thioesterase
LI65_RS05980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LI65_RS05985	COG3695	enzyme binding
LI65_RS06000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI65_RS06005	COG2364	Membrane
LI65_RS06010	COG1609	Transcriptional regulator
LI65_RS06030	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LI65_RS06040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LI65_RS06060	COG0110	maltose O-acetyltransferase activity
LI65_RS06075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS06085	COG1309	transcriptional regulator
LI65_RS06090	COG1196	nuclear chromosome segregation
LI65_RS06090	COG3264	Mechanosensitive ion channel
LI65_RS06100	COG4382	Mu-like prophage protein Gp16
LI65_RS06135	COG3409	Peptidoglycan-binding domain 1 protein
LI65_RS06135	COG3267	Type II secretory pathway component ExeA
LI65_RS06205	COG4373	Mu-like prophage FluMu protein gp28
LI65_RS06215	COG2369	cell adhesion
LI65_RS06345	COG3923	Primosomal replication protein n
LI65_RS06350	COG2832	Protein of unknown function (DUF454)
LI65_RS06355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LI65_RS06365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LI65_RS06370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LI65_RS06375	COG0326	Molecular chaperone. Has ATPase activity
LI65_RS06385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LI65_RS06390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS06395	COG4651	solute:proton antiporter activity
LI65_RS06395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI65_RS06400	COG2223	nitrite transmembrane transporter activity
LI65_RS06405	COG0737	Belongs to the 5'-nucleotidase family
LI65_RS06410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI65_RS06415	COG3735	TraB family
LI65_RS06420	COG2217	Heavy metal translocating P-type atpase
LI65_RS06430	COG1585	Membrane protein implicated in regulation of membrane protease activity
LI65_RS06435	COG0330	HflC and HflK could
LI65_RS06445	COG4619	ABC transporter
LI65_RS06450	COG0390	transport system, permease component
LI65_RS06455	COG3118	belongs to the thioredoxin family
LI65_RS06460	COG0300	oxidoreductase activity
LI65_RS06465	COG2755	lipolytic protein G-D-S-L family
LI65_RS06470	COG4181	ATPase activity
LI65_RS06475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LI65_RS06490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LI65_RS06495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LI65_RS06500	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LI65_RS06505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LI65_RS06515	COG1988	membrane-bound metal-dependent
LI65_RS06520	COG1609	Transcriptional regulator
LI65_RS06525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS06525	COG1263	PTS System
LI65_RS06525	COG2190	(PTS) system
LI65_RS06530	COG2501	S4 domain
LI65_RS06590	COG0582	viral genome integration into host DNA
LI65_RS06635	COG2246	polysaccharide biosynthetic process
LI65_RS06650	COG2135	peptidase activity
LI65_RS06670	COG1113	amino acid transport
LI65_RS06675	COG2211	Major facilitator Superfamily
LI65_RS06690	COG1609	Transcriptional regulator
LI65_RS06695	COG0668	transmembrane transport
LI65_RS06700	COG0477	Major facilitator Superfamily
LI65_RS06720	COG0778	Nitroreductase
LI65_RS06725	COG2315	Protein conserved in bacteria
LI65_RS06740	COG2207	Transcriptional regulator
LI65_RS06745	COG4774	siderophore transport
LI65_RS06775	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LI65_RS06785	COG5499	transcription regulator containing HTH domain
LI65_RS06825	COG4608	Belongs to the ABC transporter superfamily
LI65_RS06830	COG0444	Belongs to the ABC transporter superfamily
LI65_RS06835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI65_RS06840	COG0601	transmembrane transport
LI65_RS06870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LI65_RS06900	COG1121	(ABC) transporter
LI65_RS06905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI65_RS06910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI65_RS06915	COG2977	Belongs to the P-Pant transferase superfamily
LI65_RS06920	COG4771	TonB-dependent receptor
LI65_RS06925	COG2382	esterase
LI65_RS06930	COG3251	PFAM MbtH domain protein
LI65_RS06935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LI65_RS06935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LI65_RS06940	COG1120	ATPase activity
LI65_RS06945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS06950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS06960	COG4592	Periplasmic binding protein
LI65_RS06965	COG1169	isochorismate synthase
LI65_RS06970	COG1021	2,3-dihydroxybenzoate-AMP ligase
LI65_RS06975	COG1535	isochorismatase
LI65_RS06975	COG3433	isochorismatase activity
LI65_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS06985	COG2050	protein possibly involved in aromatic compounds catabolism
LI65_RS06990	COG1966	Carbon starvation protein
LI65_RS06995	COG2879	small protein
LI65_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS07015	COG0371	Dehydrogenase
LI65_RS07020	COG1129	ABC transporter
LI65_RS07025	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS07040	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LI65_RS07055	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LI65_RS07060	COG0235	Class ii aldolase
LI65_RS07065	COG0436	Aminotransferase
LI65_RS07070	COG1475	DNA binding
LI65_RS07075	COG3969	phosphoadenosine phosphosulfate
LI65_RS07080	COG0583	DNA-binding transcription factor activity
LI65_RS07100	COG1063	alcohol dehydrogenase
LI65_RS07105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LI65_RS07115	COG2207	Transcriptional regulator
LI65_RS07120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LI65_RS07120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS07120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS07125	COG1363	Peptidase, m42
LI65_RS07130	COG0006	proline dipeptidase activity
LI65_RS07135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS07140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS07145	COG3719	Belongs to the RNase T2 family
LI65_RS07150	COG3069	C4-dicarboxylate transmembrane transporter activity
LI65_RS07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS07175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS07195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI65_RS07200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LI65_RS07205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LI65_RS07210	COG0583	DNA-binding transcription factor activity
LI65_RS07215	COG0321	lipoyl(octanoyl) transferase activity
LI65_RS07225	COG1686	Belongs to the peptidase S11 family
LI65_RS07230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LI65_RS07235	COG0772	Belongs to the SEDS family
LI65_RS07240	COG0768	penicillin binding
LI65_RS07250	COG0799	negative regulation of ribosome biogenesis
LI65_RS07260	COG1466	dna polymerase III delta subunit
LI65_RS07275	COG2888	peptidyl-tyrosine sulfation
LI65_RS07280	COG1957	nucleoside hydrolase
LI65_RS07285	COG1126	abc transporter atp-binding protein
LI65_RS07290	COG0765	amino acid transport
LI65_RS07295	COG0765	amino acid transport
LI65_RS07315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LI65_RS07320	COG1702	phosphate starvation-inducible protein PhoH
LI65_RS07325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LI65_RS07330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI65_RS07375	COG0367	asparagine synthase
LI65_RS07380	COG0647	UMP catabolic process
LI65_RS07385	COG1846	Transcriptional regulator
LI65_RS07385	COG1940	carbohydrate kinase activity
LI65_RS07390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LI65_RS07405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LI65_RS07410	COG1653	transport
LI65_RS07420	COG1609	Transcriptional regulator
LI65_RS07435	COG0735	belongs to the Fur family
LI65_RS07450	COG0596	Alpha beta hydrolase
LI65_RS07455	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LI65_RS07460	COG0033	Phosphoglucomutase
LI65_RS07465	COG0531	amino acid
LI65_RS07470	COG1982	Orn Lys Arg decarboxylase major
LI65_RS07475	COG0745	RESPONSE REGULATOR receiver
LI65_RS07480	COG2205	protein histidine kinase activity
LI65_RS07485	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LI65_RS07490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LI65_RS07495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LI65_RS07510	COG0415	Belongs to the DNA photolyase family
LI65_RS07515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LI65_RS07520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LI65_RS07525	COG1984	allophanate hydrolase subunit 2
LI65_RS07535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LI65_RS07540	COG0372	Belongs to the citrate synthase family
LI65_RS07545	COG2009	succinate dehydrogenase
LI65_RS07550	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LI65_RS07555	COG1053	succinate dehydrogenase
LI65_RS07560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LI65_RS07565	COG0567	Dehydrogenase, E1 component
LI65_RS07570	COG0508	dehydrogenase complex catalyzes the overall conversion of
LI65_RS07575	COG0045	succinate-CoA ligase (ADP-forming) activity
LI65_RS07580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LI65_RS07585	COG2188	Transcriptional regulator
LI65_RS07590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS07590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS07590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS07595	COG0383	alpha-mannosidase activity
LI65_RS07600	COG1271	oxidase subunit
LI65_RS07605	COG1294	oxidase, subunit
LI65_RS07610	COG4890	Cyd operon protein YbgT
LI65_RS07615	COG3790	cyd operon protein YbgE
LI65_RS07620	COG0824	Thioesterase
LI65_RS07625	COG0811	peptide transport
LI65_RS07630	COG0848	biopolymer transport protein
LI65_RS07635	COG3064	Membrane
LI65_RS07640	COG0823	Involved in the tonB-independent uptake of proteins
LI65_RS07645	COG2885	chlorophyll binding
LI65_RS07650	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LI65_RS07685	COG3201	nicotinamide mononucleotide transporter
LI65_RS07690	COG1230	cation diffusion facilitator family transporter
LI65_RS07700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI65_RS07710	COG2017	converts alpha-aldose to the beta-anomer
LI65_RS07715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LI65_RS07720	COG1085	galactose-1-phosphate uridylyltransferase
LI65_RS07725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LI65_RS07730	COG1119	ATPase activity
LI65_RS07735	COG2005	Transcriptional regulator
LI65_RS07735	COG3585	molybdate ion transport
LI65_RS07745	COG0725	ABC transporter, periplasmic molybdate-binding protein
LI65_RS07750	COG4149	molybdate abc transporter
LI65_RS07760	COG0561	phosphatase activity
LI65_RS07765	COG2706	6-phosphogluconolactonase activity
LI65_RS07770	COG4677	pectinesterase activity
LI65_RS07780	COG0010	Belongs to the arginase family
LI65_RS07790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LI65_RS07795	COG2986	histidine ammonia-lyase
LI65_RS07800	COG1881	PFAM PEBP family protein
LI65_RS07805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LI65_RS07810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LI65_RS07815	COG0156	8-amino-7-oxononanoate synthase activity
LI65_RS07820	COG2226	methyltransferase
LI65_RS07850	COG0521	Mo-molybdopterin cofactor biosynthetic process
LI65_RS07855	COG0315	cyclic pyranopterin monophosphate synthase activity
LI65_RS07860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LI65_RS07865	COG0314	molybdopterin synthase activity
LI65_RS07870	COG0670	Belongs to the BI1 family
LI65_RS07875	COG0392	lysyltransferase activity
LI65_RS07880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LI65_RS07885	COG3568	Endonuclease Exonuclease Phosphatase
LI65_RS07895	COG0842	Transport permease protein
LI65_RS07900	COG0842	Transport permease protein
LI65_RS07905	COG1131	(ABC) transporter
LI65_RS07910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS07915	COG1309	transcriptional regulator
LI65_RS07920	COG0513	Belongs to the DEAD box helicase family
LI65_RS07925	COG1199	ATP-dependent helicase activity
LI65_RS07945	COG3121	Chaperone
LI65_RS07950	COG3539	Fimbrial protein
LI65_RS07955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LI65_RS07965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LI65_RS07980	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LI65_RS07985	COG0668	transmembrane transport
LI65_RS07990	COG1126	abc transporter atp-binding protein
LI65_RS07995	COG0765	amino acid transport
LI65_RS08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS08005	COG0783	Belongs to the Dps family
LI65_RS08015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LI65_RS08020	COG2194	sulfuric ester hydrolase activity
LI65_RS08030	COG1321	iron dependent repressor
LI65_RS08035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LI65_RS08040	COG1566	PFAM secretion protein HlyD family protein
LI65_RS08045	COG2814	Major facilitator Superfamily
LI65_RS08055	COG0667	Aldo Keto reductase
LI65_RS08065	COG2819	hydrolase of the alpha beta superfamily
LI65_RS08070	COG2382	esterase
LI65_RS08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS08095	COG1538	Outer membrane efflux protein
LI65_RS08100	COG2723	6-phospho-beta-galactosidase activity
LI65_RS08105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS08110	COG2188	Transcriptional regulator
LI65_RS08115	COG1376	ErfK ybiS ycfS ynhG family protein
LI65_RS08120	COG0488	(ABC) transporter
LI65_RS08135	COG1609	Transcriptional regulator
LI65_RS08145	COG0561	phosphatase activity
LI65_RS08150	COG1882	Formate acetyltransferase
LI65_RS08155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI65_RS08160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LI65_RS08170	COG0303	'Molybdopterin
LI65_RS08175	COG1446	asparaginase
LI65_RS08210	COG2133	pyrroloquinoline quinone binding
LI65_RS08215	COG0625	glutathione transferase activity
LI65_RS08220	COG1686	Belongs to the peptidase S11 family
LI65_RS08225	COG1349	DNA-binding transcription factor activity
LI65_RS08230	COG0671	phosphoesterase, PA-phosphatase related
LI65_RS08240	COG2814	Major facilitator Superfamily
LI65_RS08245	COG0561	phosphatase activity
LI65_RS08250	COG0738	Major facilitator superfamily
LI65_RS08255	COG3226	Transcriptional regulator
LI65_RS08260	COG1393	Belongs to the ArsC family
LI65_RS08265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LI65_RS08270	COG0640	Transcriptional regulator
LI65_RS08300	COG0778	Nitroreductase
LI65_RS08315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LI65_RS08320	COG3842	ATPase activity
LI65_RS08325	COG1176	ABC-type spermidine putrescine transport system, permease component I
LI65_RS08330	COG1177	transmembrane transport
LI65_RS08340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI65_RS08350	COG0745	RESPONSE REGULATOR receiver
LI65_RS08355	COG5002	protein histidine kinase activity
LI65_RS08360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS08365	COG4160	amino acid transport
LI65_RS08370	COG4215	(ABC) transporter
LI65_RS08375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS08380	COG1126	abc transporter atp-binding protein
LI65_RS08390	COG0393	Putative heavy-metal-binding
LI65_RS08395	COG3023	N-Acetylmuramoyl-L-alanine amidase
LI65_RS08420	COG1450	Type ii and iii secretion system protein
LI65_RS08435	COG3397	chitin binding
LI65_RS08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI65_RS08445	COG0702	epimerase
LI65_RS08450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LI65_RS08455	COG0028	Belongs to the TPP enzyme family
LI65_RS08460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI65_RS08465	COG1151	hydroxylamine reductase activity
LI65_RS08470	COG2431	L-lysine efflux transmembrane transporter activity
LI65_RS08480	COG3593	DNA synthesis involved in DNA repair
LI65_RS08485	COG2990	Protein conserved in bacteria
LI65_RS08490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS08500	COG1278	Cold shock
LI65_RS08505	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LI65_RS08510	COG0542	response to heat
LI65_RS08515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LI65_RS08520	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LI65_RS08525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LI65_RS08530	COG4988	ABC transporter
LI65_RS08535	COG0492	ferredoxin-NADP+ reductase activity
LI65_RS08545	COG1178	ABC-type Fe3 transport system permease component
LI65_RS08545	COG1674	ftsk spoiiie
LI65_RS08550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LI65_RS08555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LI65_RS08560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LI65_RS08565	COG0243	molybdopterin cofactor binding
LI65_RS08570	COG0437	4 iron, 4 sulfur cluster binding
LI65_RS08575	COG3302	dmso reductase anchor subunit
LI65_RS08580	COG0477	Major facilitator Superfamily
LI65_RS08590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LI65_RS08595	COG1882	Formate acetyltransferase
LI65_RS08600	COG2116	formate transmembrane transporter activity
LI65_RS08605	COG1944	ATP diphosphatase activity
LI65_RS08610	COG2323	membrane
LI65_RS08615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LI65_RS08620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LI65_RS08625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LI65_RS08630	COG0539	negative regulation of cytoplasmic translation
LI65_RS08635	COG0776	regulation of translation
LI65_RS08640	COG0658	competence protein
LI65_RS08640	COG2333	competence protein COMEC
LI65_RS08645	COG1132	(ABC) transporter
LI65_RS08655	COG3214	Protein conserved in bacteria
LI65_RS08660	COG2835	tetraacyldisaccharide 4'-kinase activity
LI65_RS08665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LI65_RS08670	COG3173	Aminoglycoside phosphotransferase
LI65_RS08675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LI65_RS08680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LI65_RS08690	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LI65_RS08695	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LI65_RS08700	COG2989	Protein conserved in bacteria
LI65_RS08705	COG3108	Peptidase M15
LI65_RS08710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI65_RS08715	COG1448	Aminotransferase
LI65_RS08725	COG0017	Asparaginyl-tRNA synthetase
LI65_RS08730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LI65_RS08735	COG0582	viral genome integration into host DNA
LI65_RS08800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LI65_RS08810	COG0675	Transposase, IS605 OrfB family
LI65_RS08820	COG2963	transposase activity
LI65_RS08825	COG2801	Transposase and inactivated derivatives
LI65_RS08830	COG0308	aminopeptidase N
LI65_RS08840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LI65_RS08845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS08850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LI65_RS08855	COG0431	NADPH-dependent FMN reductase
LI65_RS08860	COG0167	dihydroorotate dehydrogenase activity
LI65_RS08870	COG3217	Mosc domain protein beta barrel domain protein
LI65_RS08870	COG0633	Ferredoxin
LI65_RS08875	COG0116	Belongs to the methyltransferase superfamily
LI65_RS08875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LI65_RS08880	COG0488	(ABC) transporter
LI65_RS08885	COG2995	paraquat-inducible protein a
LI65_RS08890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LI65_RS08890	COG3008	intermembrane lipid transfer
LI65_RS08895	COG3009	Protein conserved in bacteria
LI65_RS08900	COG3130	regulation of translation
LI65_RS08910	COG1067	ATP-dependent peptidase activity
LI65_RS08915	COG3120	sequence-specific DNA binding
LI65_RS08925	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LI65_RS08930	COG3070	regulator of competence-specific genes
LI65_RS08935	COG1289	transmembrane transporter activity
LI65_RS08940	COG3304	Inner membrane component domain
LI65_RS08945	COG0210	DNA helicase
LI65_RS08950	COG1803	Methylglyoxal synthase
LI65_RS08955	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LI65_RS08960	COG1832	CoA-binding protein
LI65_RS08970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LI65_RS08975	COG1254	Belongs to the acylphosphatase family
LI65_RS08985	COG0670	Belongs to the BI1 family
LI65_RS09000	COG1120	ATPase activity
LI65_RS09005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS09015	COG3264	Mechanosensitive ion channel
LI65_RS09015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LI65_RS09030	COG2239	Acts as a magnesium transporter
LI65_RS09035	COG0586	Pfam SNARE associated Golgi protein
LI65_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS09045	COG1733	regulation of RNA biosynthetic process
LI65_RS09070	COG3729	General stress protein
LI65_RS09080	COG2233	PERMEase
LI65_RS09085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI65_RS09090	COG0778	Nitroreductase
LI65_RS09095	COG2267	carboxylic ester hydrolase activity
LI65_RS09100	COG0251	oxidation-reduction process
LI65_RS09105	COG1335	isochorismatase
LI65_RS09110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS09135	COG1309	transcriptional regulator
LI65_RS09145	COG0506	proline dehydrogenase activity
LI65_RS09145	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LI65_RS09145	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LI65_RS09150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LI65_RS09160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LI65_RS09165	COG1662	PFAM IS1 transposase
LI65_RS09175	COG2822	iron ion transport
LI65_RS09185	COG1702	phosphate starvation-inducible protein PhoH
LI65_RS09190	COG1115	amino acid carrier protein
LI65_RS09200	COG1335	isochorismatase
LI65_RS09210	COG0583	DNA-binding transcription factor activity
LI65_RS09220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI65_RS09225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LI65_RS09230	COG3381	protein complex oligomerization
LI65_RS09280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LI65_RS09295	COG2943	transferase activity, transferring hexosyl groups
LI65_RS09300	COG5645	(Lipo)protein
LI65_RS09315	COG1560	Kdo2-lipid A biosynthetic process
LI65_RS09320	COG1054	Belongs to the UPF0176 family
LI65_RS09325	COG2353	YceI-like domain
LI65_RS09330	COG3038	cytochrome b561
LI65_RS09355	COG0418	dihydroorotase activity
LI65_RS09365	COG0477	Major facilitator Superfamily
LI65_RS09370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS09375	COG3132	Protein of unknown function, DUF480
LI65_RS09410	COG1558	bacterial-type flagellum-dependent cell motility
LI65_RS09420	COG1749	Flagellar hook protein flgE
LI65_RS09430	COG4786	Flagellar basal body rod
LI65_RS09450	COG1256	bacterial-type flagellum assembly
LI65_RS09460	COG2814	Major facilitator Superfamily
LI65_RS09465	COG0583	DNA-binding transcription factor activity
LI65_RS09470	COG1530	ribonuclease E activity
LI65_RS09475	COG0564	pseudouridine synthase activity
LI65_RS09480	COG0424	maF-like protein
LI65_RS09490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LI65_RS09495	COG0416	fatty acid biosynthetic process
LI65_RS09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LI65_RS09515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LI65_RS09520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI65_RS09525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LI65_RS09530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LI65_RS09540	COG0470	DNA polymerase III
LI65_RS09545	COG0084	hydrolase, TatD family'
LI65_RS09555	COG4773	Receptor
LI65_RS09560	COG0537	adenosine 5'-monophosphoramidase activity
LI65_RS09565	COG5633	Lipoprotein
LI65_RS09570	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LI65_RS09585	COG3150	esterase
LI65_RS09590	COG1252	NADH dehydrogenase
LI65_RS09595	COG3134	Outer membrane lipoprotein
LI65_RS09600	COG1309	transcriptional regulator
LI65_RS09610	COG1388	LysM domain
LI65_RS09610	COG1376	ErfK ybiS ycfS ynhG family protein
LI65_RS09615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LI65_RS09620	COG4763	Acyl-transferase
LI65_RS09625	COG4591	ABC-type transport system involved in lipoprotein release permease component
LI65_RS09630	COG1136	(ABC) transporter
LI65_RS09635	COG4591	ABC-type transport system involved in lipoprotein release permease component
LI65_RS09645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LI65_RS09680	COG1943	Transposase
LI65_RS09685	COG2850	peptidyl-arginine hydroxylation
LI65_RS09690	COG2205	protein histidine kinase activity
LI65_RS09705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LI65_RS09710	COG2915	High frequency lysogenization protein hflD homolog
LI65_RS09725	COG1187	pseudouridine synthase activity
LI65_RS09730	COG0538	isocitrate dehydrogenase activity
LI65_RS09740	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LI65_RS09745	COG2261	transglycosylase associated protein
LI65_RS09750	COG2199	diguanylate cyclase activity
LI65_RS09750	COG2203	Gaf domain
LI65_RS09755	COG3042	response to heat
LI65_RS09765	COG3189	MarR family transcriptional regulator
LI65_RS09770	COG0504	CTP synthase activity
LI65_RS09775	COG2807	transmembrane transport
LI65_RS09780	COG2207	Transcriptional regulator
LI65_RS09785	COG2707	UPF0756 membrane protein
LI65_RS09795	COG2211	Major facilitator Superfamily
LI65_RS09800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LI65_RS09805	COG2718	Belongs to the UPF0229 family
LI65_RS09810	COG2766	serine protein kinase
LI65_RS09815	COG3713	MltA-interacting MipA family protein
LI65_RS09835	COG3139	Protein of unknown function (DUF1315)
LI65_RS09845	COG1335	isochorismatase
LI65_RS09850	COG0252	asparaginase activity
LI65_RS09855	COG0616	signal peptide processing
LI65_RS09860	COG0778	Nitroreductase
LI65_RS09865	COG0709	Synthesizes selenophosphate from selenide and ATP
LI65_RS09870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LI65_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS09880	COG1263	PTS System
LI65_RS09890	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LI65_RS09915	COG0494	nUDIX hydrolase
LI65_RS09920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI65_RS09925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LI65_RS09930	COG2897	thiosulfate sulfurtransferase activity
LI65_RS09935	COG4136	ATPase activity
LI65_RS09940	COG4135	transport system, permease component
LI65_RS09945	COG4134	Bacterial extracellular solute-binding protein
LI65_RS09955	COG0708	Exodeoxyribonuclease III
LI65_RS09965	COG3138	arginine N-succinyltransferase
LI65_RS09970	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS09975	COG3724	N-succinylarginine dihydrolase activity
LI65_RS09985	COG3678	ATP-independent chaperone mediated protein folding
LI65_RS09995	COG0322	excinuclease ABC activity
LI65_RS10005	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS10010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS10015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS10020	COG1447	Phosphotransferase system cellobiose-specific component IIA
LI65_RS10025	COG1917	Cupin 2, conserved barrel domain protein
LI65_RS10025	COG2169	Transcriptional regulator
LI65_RS10030	COG1486	melibiose metabolic process
LI65_RS10035	COG3394	polysaccharide catabolic process
LI65_RS10040	COG0753	catalase activity
LI65_RS10050	COG1823	symporter activity
LI65_RS10055	COG1988	membrane-bound metal-dependent
LI65_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS10065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS10075	COG3001	Fructosamine kinase
LI65_RS10085	COG1105	Belongs to the carbohydrate kinase PfkB family
LI65_RS10090	COG3137	Salt-induced outer membrane protein
LI65_RS10120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LI65_RS10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LI65_RS10125	COG0072	phenylalanine-tRNA ligase activity
LI65_RS10130	COG0776	regulation of translation
LI65_RS10140	COG0582	viral genome integration into host DNA
LI65_RS10165	COG1846	Transcriptional regulator
LI65_RS10225	COG0484	heat shock protein binding
LI65_RS10240	COG3772	lysozyme
LI65_RS10290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LI65_RS10310	COG2135	peptidase activity
LI65_RS10315	COG0386	Belongs to the glutathione peroxidase family
LI65_RS10325	COG0791	NLP P60 protein
LI65_RS10335	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LI65_RS10345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS10350	COG4558	Periplasmic binding protein
LI65_RS10355	COG3720	iron ion transport
LI65_RS10365	COG4256	Hemin uptake protein
LI65_RS10370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI65_RS10375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LI65_RS10380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LI65_RS10380	COG0574	Belongs to the PEP-utilizing enzyme family
LI65_RS10385	COG2211	Major facilitator Superfamily
LI65_RS10390	COG1472	Belongs to the glycosyl hydrolase 3 family
LI65_RS10395	COG0628	permease
LI65_RS10400	COG0247	lactate metabolic process
LI65_RS10400	COG0277	FAD linked oxidase domain protein
LI65_RS10405	COG2050	protein possibly involved in aromatic compounds catabolism
LI65_RS10415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LI65_RS10430	COG3121	Chaperone
LI65_RS10455	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS10475	COG2200	EAL domain
LI65_RS10480	COG0789	Transcriptional regulator
LI65_RS10495	COG0316	Belongs to the HesB IscA family
LI65_RS10500	COG0719	Fe-S assembly protein
LI65_RS10505	COG0396	ATPase activity
LI65_RS10510	COG0719	Fe-S assembly protein
LI65_RS10515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LI65_RS10520	COG2166	iron-sulfur cluster assembly
LI65_RS10525	COG1376	ErfK ybiS ycfS ynhG family protein
LI65_RS10540	COG0626	cystathionine gamma-synthase activity
LI65_RS10555	COG2011	ABC-type metal ion transport system permease component
LI65_RS10560	COG1464	Belongs to the NlpA lipoprotein family
LI65_RS10570	COG0765	amino acid transport
LI65_RS10585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS10605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI65_RS10615	COG4529	Protein conserved in bacteria
LI65_RS10625	COG0071	Belongs to the small heat shock protein (HSP20) family
LI65_RS10645	COG0307	riboflavin synthase, alpha
LI65_RS10650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LI65_RS10655	COG2814	Major facilitator Superfamily
LI65_RS10660	COG0583	DNA-binding transcription factor activity
LI65_RS10675	COG2814	Major facilitator Superfamily
LI65_RS10685	COG0791	NLP P60 protein
LI65_RS10690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LI65_RS10700	COG0346	lactoylglutathione lyase activity
LI65_RS10705	COG1902	pentaerythritol trinitrate reductase activity
LI65_RS10710	COG1309	transcriptional regulator
LI65_RS10715	COG2194	sulfuric ester hydrolase activity
LI65_RS10720	COG3313	Fe-S protein
LI65_RS10725	COG4989	oxidoreductase activity
LI65_RS10730	COG2032	superoxide dismutase activity
LI65_RS10735	COG1289	transmembrane transporter activity
LI65_RS10740	COG1566	PFAM secretion protein HlyD family protein
LI65_RS10755	COG3706	GGDEF domain
LI65_RS10765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LI65_RS10770	COG3895	Periplasmic Protein
LI65_RS10775	COG0259	pyridoxamine-phosphate oxidase activity
LI65_RS10780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LI65_RS10785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LI65_RS10790	COG0625	glutathione transferase activity
LI65_RS10795	COG3104	oligopeptide transport
LI65_RS10800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LI65_RS10850	COG0673	inositol 2-dehydrogenase activity
LI65_RS10855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LI65_RS10860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LI65_RS10865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS10865	COG1263	PTS System
LI65_RS10870	COG1609	Transcriptional regulator
LI65_RS10875	COG5339	Protein conserved in bacteria
LI65_RS10885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LI65_RS10885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LI65_RS10900	COG2205	protein histidine kinase activity
LI65_RS10910	COG1278	Cold shock
LI65_RS10920	COG0745	RESPONSE REGULATOR receiver
LI65_RS10925	COG3136	membrane protein required for alginate biosynthesis
LI65_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS10935	COG0531	amino acid
LI65_RS10945	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LI65_RS10950	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LI65_RS10955	COG0668	transmembrane transport
LI65_RS10960	COG0589	response to stress
LI65_RS10970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LI65_RS10975	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LI65_RS10980	COG1473	amidohydrolase
LI65_RS10990	COG0583	DNA-binding transcription factor activity
LI65_RS10995	COG2840	Smr protein MutS2
LI65_RS11005	COG0667	Aldo Keto reductase
LI65_RS11020	COG4993	Dehydrogenase
LI65_RS11055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LI65_RS11060	COG1403	HNH endonuclease
LI65_RS11065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS11075	COG0628	permease
LI65_RS11080	COG2076	Multidrug Resistance protein
LI65_RS11085	COG2076	Multidrug Resistance protein
LI65_RS11090	COG3591	Belongs to the peptidase S1B family
LI65_RS11100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LI65_RS11105	COG2814	Major facilitator Superfamily
LI65_RS11110	COG0583	DNA-binding transcription factor activity
LI65_RS11115	COG1940	carbohydrate kinase activity
LI65_RS11120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LI65_RS11180	COG3141	response to X-ray
LI65_RS11185	COG3381	protein complex oligomerization
LI65_RS11190	COG3302	dmso reductase anchor subunit
LI65_RS11195	COG0437	4 iron, 4 sulfur cluster binding
LI65_RS11220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS11235	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS11240	COG1063	alcohol dehydrogenase
LI65_RS11245	COG0477	Major facilitator Superfamily
LI65_RS11250	COG1904	glucuronate isomerase
LI65_RS11260	COG0246	Mannitol dehydrogenase
LI65_RS11270	COG0589	response to stress
LI65_RS11275	COG1802	Transcriptional regulator
LI65_RS11280	COG4221	oxidoreductase activity
LI65_RS11295	COG4773	Receptor
LI65_RS11310	COG0725	ABC transporter, periplasmic molybdate-binding protein
LI65_RS11315	COG1176	ABC-type spermidine putrescine transport system, permease component I
LI65_RS11325	COG0814	amino acid
LI65_RS11335	COG4993	Dehydrogenase
LI65_RS11350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LI65_RS11355	COG2911	Protein conserved in bacteria
LI65_RS11365	COG3784	Protein of unknown function (DUF1318)
LI65_RS11370	COG2207	Transcriptional regulator
LI65_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS11380	COG3706	GGDEF domain
LI65_RS11380	COG4251	negative regulation of phosphorylation
LI65_RS11380	COG5001	Diguanylate cyclase
LI65_RS11380	COG2203	Gaf domain
LI65_RS11385	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LI65_RS11390	COG3733	amine oxidase
LI65_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS11395	COG2030	dehydratase
LI65_RS11400	COG3396	Phenylacetate-CoA oxygenase
LI65_RS11405	COG3460	Phenylacetate-CoA oxygenase
LI65_RS11410	COG3396	Phenylacetate-CoA oxygenase
LI65_RS11415	COG2151	metal-sulfur cluster biosynthetic enzyme
LI65_RS11420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI65_RS11425	COG1024	Enoyl-CoA hydratase
LI65_RS11430	COG1024	Enoyl-CoA hydratase
LI65_RS11435	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI65_RS11440	COG2050	protein possibly involved in aromatic compounds catabolism
LI65_RS11445	COG0183	Belongs to the thiolase family
LI65_RS11450	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LI65_RS11455	COG3327	negative regulation of DNA-templated transcription, initiation
LI65_RS11460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI65_RS11470	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LI65_RS11490	COG0300	oxidoreductase activity
LI65_RS11505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LI65_RS11550	COG3122	Protein conserved in bacteria
LI65_RS11555	COG0564	pseudouridine synthase activity
LI65_RS11565	COG1643	Atp-dependent helicase
LI65_RS11570	COG1538	Outer membrane efflux protein
LI65_RS11585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LI65_RS11590	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS11595	COG3038	cytochrome b561
LI65_RS11600	COG0673	inositol 2-dehydrogenase activity
LI65_RS11605	COG1349	DNA-binding transcription factor activity
LI65_RS11620	COG2274	protein secretion by the type I secretion system
LI65_RS11680	COG0840	transmembrane signaling receptor activity
LI65_RS11685	COG0583	DNA-binding transcription factor activity
LI65_RS11690	COG5383	Protein conserved in bacteria
LI65_RS11695	COG2272	Belongs to the type-B carboxylesterase lipase family
LI65_RS11705	COG0436	Aminotransferase
LI65_RS11715	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LI65_RS11720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS11725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI65_RS11730	COG1275	C4-dicarboxylate transporter malic acid transport protein
LI65_RS11735	COG0500	methyltransferase
LI65_RS11740	COG2195	Cleaves the N-terminal amino acid of tripeptides
LI65_RS11745	COG0747	negative chemotaxis
LI65_RS11765	COG3135	benzoate transporter
LI65_RS11770	COG1396	sequence-specific DNA binding
LI65_RS11775	COG0826	peptidase U32
LI65_RS11800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LI65_RS11820	COG1122	ATPase activity
LI65_RS11830	COG3443	Belongs to the bacterial solute-binding protein 9 family
LI65_RS11835	COG2814	Major facilitator Superfamily
LI65_RS11840	COG0697	spore germination
LI65_RS11855	COG1846	Transcriptional regulator
LI65_RS11865	COG2814	Major facilitator Superfamily
LI65_RS11880	COG0583	DNA-binding transcription factor activity
LI65_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS11895	COG2066	Belongs to the glutaminase family
LI65_RS11905	COG3706	GGDEF domain
LI65_RS11915	COG0246	Mannitol dehydrogenase
LI65_RS11920	COG3781	membrane
LI65_RS11950	COG0596	Alpha beta hydrolase
LI65_RS11975	COG0494	nUDIX hydrolase
LI65_RS11980	COG1349	DNA-binding transcription factor activity
LI65_RS12010	COG2814	Major facilitator Superfamily
LI65_RS12045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LI65_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS12060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LI65_RS12070	COG0583	DNA-binding transcription factor activity
LI65_RS12080	COG0583	DNA-binding transcription factor activity
LI65_RS12090	COG4628	conserved protein (DUF2132)
LI65_RS12095	COG1649	PFAM Uncharacterised BCR, COG1649
LI65_RS12100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LI65_RS12130	COG0840	transmembrane signaling receptor activity
LI65_RS12160	COG2200	EAL domain
LI65_RS12175	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LI65_RS12180	COG0747	negative chemotaxis
LI65_RS12185	COG0601	transmembrane transport
LI65_RS12190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI65_RS12195	COG0444	Belongs to the ABC transporter superfamily
LI65_RS12200	COG4608	Belongs to the ABC transporter superfamily
LI65_RS12205	COG1764	response to oxidative stress
LI65_RS12235	COG0281	malic enzyme
LI65_RS12240	COG0488	(ABC) transporter
LI65_RS12245	COG1064	alcohol dehydrogenase
LI65_RS12255	COG1252	NADH dehydrogenase
LI65_RS12260	COG2814	Major facilitator Superfamily
LI65_RS12275	COG2864	formate dehydrogenase
LI65_RS12280	COG0437	4 iron, 4 sulfur cluster binding
LI65_RS12285	COG0243	molybdopterin cofactor binding
LI65_RS12285	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS12290	COG0243	molybdopterin cofactor binding
LI65_RS12290	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS12315	COG2223	nitrite transmembrane transporter activity
LI65_RS12320	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LI65_RS12325	COG1140	nitrate reductase beta subunit
LI65_RS12330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LI65_RS12335	COG2181	nitrate reductase activity
LI65_RS12340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LI65_RS12345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LI65_RS12355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LI65_RS12360	COG0640	Transcriptional regulator
LI65_RS12370	COG1560	Kdo2-lipid A biosynthetic process
LI65_RS12375	COG1942	4-Oxalocrotonate Tautomerase
LI65_RS12380	COG0625	glutathione transferase activity
LI65_RS12390	COG1126	abc transporter atp-binding protein
LI65_RS12405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LI65_RS12410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS12415	COG1473	amidohydrolase
LI65_RS12420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS12425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI65_RS12450	COG4772	TonB-dependent receptor
LI65_RS12455	COG1802	Transcriptional regulator
LI65_RS12460	COG2130	NADP-dependent
LI65_RS12470	COG1247	-acetyltransferase
LI65_RS12475	COG3238	Protein conserved in bacteria
LI65_RS12485	COG0747	negative chemotaxis
LI65_RS12515	COG3615	Tellurite resistance protein tehB
LI65_RS12520	COG3615	Tellurite resistance protein tehB
LI65_RS12530	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS12535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI65_RS12545	COG1271	oxidase subunit
LI65_RS12550	COG1294	oxidase, subunit
LI65_RS12560	COG3187	Heat shock protein
LI65_RS12565	COG3042	response to heat
LI65_RS12570	COG1013	pyruvate-flavodoxin oxidoreductase activity
LI65_RS12570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LI65_RS12570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI65_RS12570	COG0674	pyruvate-flavodoxin oxidoreductase activity
LI65_RS12575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI65_RS12595	COG0513	Belongs to the DEAD box helicase family
LI65_RS12605	COG0840	transmembrane signaling receptor activity
LI65_RS12625	COG4166	transmembrane transport
LI65_RS12630	COG2866	Carboxypeptidase
LI65_RS12635	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS12640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LI65_RS12650	COG3768	UPF0283 membrane protein
LI65_RS12655	COG3106	COG3106 Predicted ATPase
LI65_RS12660	COG1609	Transcriptional regulator
LI65_RS12670	COG3842	ATPase activity
LI65_RS12675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS12680	COG1554	hydrolase, family 65, central catalytic
LI65_RS12685	COG0673	inositol 2-dehydrogenase activity
LI65_RS12690	COG1082	Xylose isomerase domain protein TIM barrel
LI65_RS12695	COG1063	alcohol dehydrogenase
LI65_RS12700	COG0395	ABC-type sugar transport system, permease component
LI65_RS12705	COG1175	transmembrane transport
LI65_RS12710	COG1653	transport
LI65_RS12715	COG0366	Alpha amylase catalytic
LI65_RS12725	COG1983	PspC domain protein
LI65_RS12735	COG1842	Phage shock protein A
LI65_RS12740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LI65_RS12755	COG4171	peptide transport system, permease
LI65_RS12765	COG4172	Belongs to the ABC transporter superfamily
LI65_RS12775	COG0251	oxidation-reduction process
LI65_RS12780	COG3708	Transcriptional regulator
LI65_RS12780	COG2207	Transcriptional regulator
LI65_RS12785	COG3706	GGDEF domain
LI65_RS12790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LI65_RS12795	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI65_RS12795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LI65_RS12805	COG5001	Diguanylate cyclase
LI65_RS12810	COG1024	Enoyl-CoA hydratase
LI65_RS12820	COG1349	DNA-binding transcription factor activity
LI65_RS12830	COG0023	Translation Initiation Factor
LI65_RS12835	COG0284	orotidine-5'-phosphate decarboxylase activity
LI65_RS12840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LI65_RS12845	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LI65_RS12850	COG0671	phosphoesterase, PA-phosphatase related
LI65_RS12860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LI65_RS12895	COG0616	signal peptide processing
LI65_RS12900	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS12905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LI65_RS12915	COG0009	L-threonylcarbamoyladenylate synthase
LI65_RS12930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LI65_RS12930	COG0512	Glutamine amidotransferase of anthranilate synthase
LI65_RS12940	COG0133	tryptophan synthase activity
LI65_RS12945	COG0159	tryptophan synthase activity
LI65_RS12950	COG2391	methyltransferase activity
LI65_RS12955	COG0425	Belongs to the sulfur carrier protein TusA family
LI65_RS12960	COG3047	cAMP biosynthetic process
LI65_RS12965	COG0727	PFAM Uncharacterised protein family (UPF0153)
LI65_RS12995	COG2350	Protein conserved in bacteria
LI65_RS13000	COG1280	lysine exporter protein (LysE YggA)
LI65_RS13015	COG3099	Belongs to the UPF0263 family
LI65_RS13020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LI65_RS13025	COG4608	Belongs to the ABC transporter superfamily
LI65_RS13030	COG0444	Belongs to the ABC transporter superfamily
LI65_RS13055	COG2095	MarC family integral membrane protein
LI65_RS13060	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS13060	COG1454	alcohol dehydrogenase
LI65_RS13065	COG1435	thymidine kinase activity
LI65_RS13075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LI65_RS13080	COG0745	RESPONSE REGULATOR receiver
LI65_RS13085	COG1752	Esterase of the alpha-beta hydrolase superfamily
LI65_RS13090	COG3012	SEC-C Motif Domain Protein
LI65_RS13095	COG0788	formyltetrahydrofolate deformylase activity
LI65_RS13110	COG2181	nitrate reductase activity
LI65_RS13115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LI65_RS13120	COG1140	nitrate reductase beta subunit
LI65_RS13125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LI65_RS13130	COG2223	nitrite transmembrane transporter activity
LI65_RS13135	COG3850	Histidine kinase
LI65_RS13140	COG2197	response regulator
LI65_RS13145	COG4932	domain protein
LI65_RS13150	COG0243	molybdopterin cofactor binding
LI65_RS13155	COG2146	nitrite reductase [NAD(P)H] activity
LI65_RS13155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LI65_RS13160	COG1116	anion transmembrane transporter activity
LI65_RS13170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LI65_RS13175	COG3707	response regulator
LI65_RS13180	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LI65_RS13185	COG0840	transmembrane signaling receptor activity
LI65_RS13195	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LI65_RS13200	COG4572	Cation transport regulator
LI65_RS13205	COG0387	Pfam Sodium calcium exchanger
LI65_RS13210	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LI65_RS13225	COG2890	protein-(glutamine-N5) methyltransferase activity
LI65_RS13235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LI65_RS13245	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LI65_RS13255	COG0659	secondary active sulfate transmembrane transporter activity
LI65_RS13270	COG0193	aminoacyl-tRNA hydrolase activity
LI65_RS13275	COG0012	GTP binding
LI65_RS13285	COG3209	COG3209 Rhs family protein
LI65_RS13305	COG3209	COG3209 Rhs family protein
LI65_RS13335	COG0515	serine threonine protein kinase
LI65_RS13455	COG4977	sequence-specific DNA binding
LI65_RS13475	COG4774	siderophore transport
LI65_RS13485	COG0741	lytic transglycosylase activity
LI65_RS13490	COG1619	proteins homologs of microcin C7 resistance protein MccF
LI65_RS13495	COG3263	regulation of cellular component size
LI65_RS13500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LI65_RS13505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LI65_RS13515	COG2719	SpoVR family
LI65_RS13525	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LI65_RS13535	COG2983	Belongs to the UPF0260 family
LI65_RS13540	COG0179	Fumarylacetoacetate (FAA) hydrolase
LI65_RS13550	COG0850	regulation of cytokinetic process
LI65_RS13555	COG2894	cell division
LI65_RS13560	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LI65_RS13565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LI65_RS13570	COG0318	PFAM AMP-dependent synthetase and ligase
LI65_RS13575	COG3065	identical protein binding
LI65_RS13580	COG1214	PFAM Peptidase M22, glycoprotease
LI65_RS13585	COG1199	ATP-dependent helicase activity
LI65_RS13590	COG0251	oxidation-reduction process
LI65_RS13605	COG0494	nUDIX hydrolase
LI65_RS13610	COG1760	l-serine dehydratase
LI65_RS13615	COG2200	EAL domain
LI65_RS13620	COG1253	flavin adenine dinucleotide binding
LI65_RS13625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS13625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS13630	COG3715	PTS system
LI65_RS13635	COG3716	PTS system mannose fructose sorbose family IID component
LI65_RS13640	COG4811	Protein of unknown function (DUF986)
LI65_RS13645	COG1971	Probably functions as a manganese efflux pump
LI65_RS13650	COG2226	methyltransferase
LI65_RS13655	COG0768	penicillin binding
LI65_RS13685	COG1414	Transcriptional regulator
LI65_RS13690	COG2814	Major facilitator Superfamily
LI65_RS13695	COG0501	Belongs to the peptidase M48B family
LI65_RS13705	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LI65_RS13710	COG1956	GAF domain-containing protein
LI65_RS13715	COG2995	paraquat-inducible protein a
LI65_RS13720	COG3008	intermembrane lipid transfer
LI65_RS13725	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LI65_RS13725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LI65_RS13740	COG2990	Protein conserved in bacteria
LI65_RS13805	COG1276	copper resistance
LI65_RS13810	COG2372	response to copper ion
LI65_RS13820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LI65_RS13825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LI65_RS13830	COG1770	oligopeptidase
LI65_RS13835	COG2979	Protein of unknown function (DUF533)
LI65_RS13845	COG0800	Aldolase
LI65_RS13850	COG0129	dihydroxy-acid dehydratase activity
LI65_RS13855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LI65_RS13860	COG1737	Transcriptional regulator
LI65_RS13870	COG1560	Kdo2-lipid A biosynthetic process
LI65_RS13875	COG0739	heme binding
LI65_RS13880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LI65_RS13890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI65_RS13895	COG2255	four-way junction helicase activity
LI65_RS13900	COG0632	four-way junction helicase activity
LI65_RS13915	COG0494	nUDIX hydrolase
LI65_RS13925	COG1335	isochorismatase
LI65_RS13930	COG1801	Protein of unknown function DUF72
LI65_RS13935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LI65_RS13940	COG2226	methyltransferase
LI65_RS13945	COG0500	methyltransferase
LI65_RS13950	COG3142	Participates in the control of copper homeostasis
LI65_RS13955	COG3102	Protein conserved in bacteria
LI65_RS13960	COG0018	arginyl-trna synthetase
LI65_RS13965	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LI65_RS13995	COG0745	RESPONSE REGULATOR receiver
LI65_RS14010	COG0840	transmembrane signaling receptor activity
LI65_RS14045	COG1301	dicarboxylic acid transport
LI65_RS14085	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LI65_RS14095	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS14105	COG1879	ABC-type sugar transport system periplasmic component
LI65_RS14115	COG1528	Iron-storage protein
LI65_RS14120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LI65_RS14145	COG1528	Iron-storage protein
LI65_RS14155	COG0814	amino acid
LI65_RS14160	COG3318	Belongs to the UPF0149 family
LI65_RS14160	COG3012	SEC-C Motif Domain Protein
LI65_RS14195	COG0583	DNA-binding transcription factor activity
LI65_RS14225	COG2197	response regulator
LI65_RS14235	COG2197	response regulator
LI65_RS14240	COG1126	abc transporter atp-binding protein
LI65_RS14245	COG0765	amino acid transport
LI65_RS14255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS14275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LI65_RS14280	COG1516	flagellar protein fliS
LI65_RS14290	COG0366	Alpha amylase catalytic
LI65_RS14300	COG1677	Flagellar hook-basal body complex protein FliE
LI65_RS14310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LI65_RS14320	COG1157	protein secretion by the type III secretion system
LI65_RS14360	COG1987	bacterial-type flagellum assembly
LI65_RS14370	COG2197	response regulator
LI65_RS14395	COG5475	Uncharacterized small protein (DUF2158)
LI65_RS14400	COG2354	Protein conserved in bacteria
LI65_RS14405	COG0697	spore germination
LI65_RS14410	COG3727	T/G mismatch-specific endonuclease activity
LI65_RS14415	COG0270	DNA (cytosine-5-)-methyltransferase activity
LI65_RS14420	COG1418	mRNA catabolic process
LI65_RS14425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI65_RS14435	COG3290	protein histidine kinase activity
LI65_RS14440	COG4565	transcriptional regulatory protein
LI65_RS14460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LI65_RS14460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LI65_RS14485	COG0583	DNA-binding transcription factor activity
LI65_RS14545	COG0737	Belongs to the 5'-nucleotidase family
LI65_RS14550	COG0737	Belongs to the 5'-nucleotidase family
LI65_RS14575	COG1376	ErfK ybiS ycfS ynhG family protein
LI65_RS14580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LI65_RS14585	COG0589	response to stress
LI65_RS14595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS14610	COG0477	Major facilitator Superfamily
LI65_RS14615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LI65_RS14625	COG0534	Mate efflux family protein
LI65_RS14640	COG1289	transmembrane transporter activity
LI65_RS14645	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LI65_RS14655	COG2925	Exonuclease
LI65_RS14660	COG0531	amino acid
LI65_RS14665	COG0583	DNA-binding transcription factor activity
LI65_RS14670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI65_RS14675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LI65_RS14680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LI65_RS14685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LI65_RS14695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LI65_RS14700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LI65_RS14705	COG0107	imidazoleglycerol-phosphate synthase activity
LI65_RS14740	COG1091	dTDP-4-dehydrorhamnose reductase activity
LI65_RS14760	COG1662	PFAM IS1 transposase
LI65_RS14765	COG0438	transferase activity, transferring glycosyl groups
LI65_RS14795	COG0438	transferase activity, transferring glycosyl groups
LI65_RS14800	COG2327	Polysaccharide pyruvyl transferase
LI65_RS14805	COG2244	polysaccharide biosynthetic process
LI65_RS14810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LI65_RS14815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LI65_RS14825	COG0297	glycogen (starch) synthase activity
LI65_RS14830	COG1051	belongs to the nudix hydrolase family
LI65_RS14835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LI65_RS14840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LI65_RS14845	COG0110	maltose O-acetyltransferase activity
LI65_RS14850	COG1216	Glycosyl transferase, family 2
LI65_RS14860	COG0438	transferase activity, transferring glycosyl groups
LI65_RS14865	COG1045	serine acetyltransferase
LI65_RS14870	COG0463	Glycosyl transferase, family 2
LI65_RS14875	COG0489	protein tyrosine kinase activity
LI65_RS14875	COG3206	protein involved in exopolysaccharide biosynthesis
LI65_RS14890	COG1253	flavin adenine dinucleotide binding
LI65_RS14895	COG2982	Protein involved in outer membrane biogenesis
LI65_RS14900	COG0717	Belongs to the dCTP deaminase family
LI65_RS14910	COG3447	MASE1 domain protein
LI65_RS14910	COG5001	Diguanylate cyclase
LI65_RS14910	COG5002	protein histidine kinase activity
LI65_RS14915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LI65_RS14920	COG0443	Heat shock 70 kDa protein
LI65_RS14930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS14935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS14940	COG0477	Major facilitator Superfamily
LI65_RS14945	COG2205	protein histidine kinase activity
LI65_RS14950	COG0745	RESPONSE REGULATOR receiver
LI65_RS14955	COG0826	peptidase U32
LI65_RS14960	COG1597	lipid kinase activity
LI65_RS14965	COG4608	Belongs to the ABC transporter superfamily
LI65_RS14970	COG0444	Belongs to the ABC transporter superfamily
LI65_RS14975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LI65_RS14980	COG0601	transmembrane transport
LI65_RS14985	COG0747	negative chemotaxis
LI65_RS14990	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS14995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS15005	COG1070	Carbohydrate kinase
LI65_RS15030	COG1070	Carbohydrate kinase
LI65_RS15040	COG1830	Aldolase
LI65_RS15045	COG2211	Major facilitator Superfamily
LI65_RS15050	COG1397	ADP-ribosylglycohydrolase
LI65_RS15055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS15060	COG2188	Transcriptional regulator
LI65_RS15065	COG0351	phosphomethylpyrimidine kinase
LI65_RS15070	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LI65_RS15090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LI65_RS15095	COG0076	glutamate decarboxylase activity
LI65_RS15100	COG0489	protein tyrosine kinase activity
LI65_RS15100	COG3206	protein involved in exopolysaccharide biosynthesis
LI65_RS15105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LI65_RS15110	COG1596	polysaccharide export
LI65_RS15115	COG5455	response to cobalt ion
LI65_RS15125	COG0489	protein tyrosine kinase activity
LI65_RS15135	COG4807	Protein conserved in bacteria
LI65_RS15145	COG3275	phosphorelay sensor kinase activity
LI65_RS15150	COG0789	Transcriptional regulator
LI65_RS15155	COG1174	glycine betaine transport
LI65_RS15160	COG1125	glycine betaine transport
LI65_RS15165	COG1174	glycine betaine transport
LI65_RS15170	COG1732	Glycine betaine
LI65_RS15175	COG1472	Belongs to the glycosyl hydrolase 3 family
LI65_RS15180	COG0277	FAD linked oxidase domain protein
LI65_RS15190	COG1686	Belongs to the peptidase S11 family
LI65_RS15200	COG0586	Pfam SNARE associated Golgi protein
LI65_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS15210	COG1538	Outer membrane efflux protein
LI65_RS15215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LI65_RS15225	COG1346	cytolysis
LI65_RS15230	COG0295	cytidine deaminase activity
LI65_RS15235	COG2949	membrane
LI65_RS15245	COG1129	ABC transporter
LI65_RS15260	COG2311	Membrane
LI65_RS15270	COG0477	Major facilitator Superfamily
LI65_RS15275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LI65_RS15280	COG4771	TonB-dependent receptor
LI65_RS15285	COG0833	amino acid
LI65_RS15290	COG0583	DNA-binding transcription factor activity
LI65_RS15295	COG2855	membrane
LI65_RS15300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LI65_RS15305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LI65_RS15305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS15305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LI65_RS15310	COG1105	Belongs to the carbohydrate kinase PfkB family
LI65_RS15315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS15315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS15330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LI65_RS15335	COG1312	Catalyzes the dehydration of D-mannonate
LI65_RS15340	COG0246	Mannitol dehydrogenase
LI65_RS15345	COG0523	cobalamin synthesis protein
LI65_RS15350	COG0671	phosphoesterase, PA-phosphatase related
LI65_RS15355	COG0791	NLP P60 protein
LI65_RS15360	COG2200	EAL domain
LI65_RS15365	COG4166	transmembrane transport
LI65_RS15370	COG4174	ABC transporter (Permease)
LI65_RS15375	COG4239	(ABC) transporter, permease
LI65_RS15380	COG4172	Belongs to the ABC transporter superfamily
LI65_RS15390	COG2814	Major facilitator Superfamily
LI65_RS15395	COG1187	pseudouridine synthase activity
LI65_RS15400	COG1061	Type III restriction enzyme res subunit
LI65_RS15410	COG3081	Nucleoid-associated protein
LI65_RS15415	COG3082	Protein of unknown function (DUF1414)
LI65_RS15430	COG3182	Iron-regulated membrane protein
LI65_RS15440	COG0579	oxidoreductase
LI65_RS15445	COG0659	secondary active sulfate transmembrane transporter activity
LI65_RS15450	COG2239	Acts as a magnesium transporter
LI65_RS15455	COG4615	Cyclic peptide transporter
LI65_RS15465	COG2169	Transcriptional regulator
LI65_RS15465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LI65_RS15475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LI65_RS15480	COG0642	Histidine kinase
LI65_RS15480	COG2198	Histidine kinase
LI65_RS15500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LI65_RS15515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI65_RS15520	COG0584	glycerophosphoryl diester phosphodiesterase
LI65_RS15525	COG2271	Major facilitator Superfamily
LI65_RS15530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LI65_RS15535	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LI65_RS15540	COG0247	lactate metabolic process
LI65_RS15585	COG1441	menaquinone biosynthetic process
LI65_RS15595	COG0596	Alpha beta hydrolase
LI65_RS15600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LI65_RS15605	COG1169	isochorismate synthase
LI65_RS15610	COG4575	ribosome binding
LI65_RS15615	COG2153	protein acetylation
LI65_RS15620	COG1234	tRNA 3'-trailer cleavage
LI65_RS15625	COG0835	chemotaxis
LI65_RS15625	COG0784	Response regulator, receiver
LI65_RS15630	COG1007	ATP synthesis coupled electron transport
LI65_RS15635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI65_RS15640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LI65_RS15645	COG0713	ATP synthesis coupled electron transport
LI65_RS15650	COG0839	Belongs to the complex I subunit 6 family
LI65_RS15660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LI65_RS15690	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI65_RS15695	COG0583	DNA-binding transcription factor activity
LI65_RS15700	COG0436	Aminotransferase
LI65_RS15710	COG0490	domain, Protein
LI65_RS15710	COG0471	metal ion transport
LI65_RS15715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS15740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LI65_RS15745	COG3959	Transketolase, thiamine diphosphate binding domain
LI65_RS15750	COG3037	sugar-specific permease SgaT UlaA
LI65_RS15760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS15765	COG1609	Transcriptional regulator
LI65_RS15775	COG0622	Phosphoesterase
LI65_RS15780	COG0625	glutathione transferase activity
LI65_RS15785	COG0625	glutathione transferase activity
LI65_RS15790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LI65_RS15795	COG1090	epimerase
LI65_RS15800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS15805	COG4598	ABC transporter
LI65_RS15810	COG4160	amino acid transport
LI65_RS15820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS15830	COG0163	prenyltransferase activity
LI65_RS15835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LI65_RS15840	COG1286	toxin biosynthetic process
LI65_RS15845	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LI65_RS15850	COG0285	dihydrofolate synthase activity
LI65_RS15860	COG0586	Pfam SNARE associated Golgi protein
LI65_RS15865	COG0101	tRNA pseudouridine synthase activity
LI65_RS15870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LI65_RS15875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI65_RS15890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI65_RS15895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LI65_RS15895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LI65_RS15905	COG3101	peptidyl-lysine hydroxylation
LI65_RS15910	COG0730	response to heat
LI65_RS15920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LI65_RS15930	COG2840	Smr protein MutS2
LI65_RS15935	COG2062	phosphohistidine phosphatase, SixA
LI65_RS15940	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI65_RS15940	COG1024	Enoyl-CoA hydratase
LI65_RS15950	COG3691	Protein conserved in bacteria
LI65_RS15955	COG2067	long-chain fatty acid transport protein
LI65_RS15965	COG2116	formate transmembrane transporter activity
LI65_RS15975	COG3706	GGDEF domain
LI65_RS15980	COG1560	Kdo2-lipid A biosynthetic process
LI65_RS15990	COG0436	Aminotransferase
LI65_RS15995	COG3275	phosphorelay sensor kinase activity
LI65_RS16000	COG3279	Response regulator of the LytR AlgR family
LI65_RS16005	COG0837	glucose binding
LI65_RS16015	COG3961	Belongs to the TPP enzyme family
LI65_RS16020	COG0667	Aldo Keto reductase
LI65_RS16030	COG1914	H( )-stimulated, divalent metal cation uptake system
LI65_RS16035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LI65_RS16040	COG2200	EAL domain
LI65_RS16040	COG2199	diguanylate cyclase activity
LI65_RS16055	COG3415	Transposase
LI65_RS16060	COG3415	Transposase
LI65_RS16065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LI65_RS16100	COG0583	DNA-binding transcription factor activity
LI65_RS16105	COG0385	Bile acid
LI65_RS16110	COG3530	Putative quorum-sensing-regulated virulence factor
LI65_RS16115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LI65_RS16120	COG3115	cell septum assembly
LI65_RS16135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS16160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LI65_RS16165	COG4208	sulfate ABC transporter
LI65_RS16170	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LI65_RS16175	COG4150	thiosulfate binding
LI65_RS16180	COG2837	iron assimilation
LI65_RS16205	COG0408	coproporphyrinogen oxidase activity
LI65_RS16220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LI65_RS16225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LI65_RS16230	COG1609	Transcriptional regulator
LI65_RS16235	COG3250	beta-galactosidase activity
LI65_RS16240	COG2731	YhcH YjgK YiaL family protein
LI65_RS16245	COG0531	amino acid
LI65_RS16255	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LI65_RS16255	COG3408	Glycogen debranching enzyme
LI65_RS16260	COG5342	invasion associated locus B
LI65_RS16265	COG0494	nUDIX hydrolase
LI65_RS16270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI65_RS16270	COG0493	'glutamate synthase
LI65_RS16280	COG3850	Histidine kinase
LI65_RS16285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS16290	COG1393	Belongs to the ArsC family
LI65_RS16295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LI65_RS16305	COG0400	carboxylic ester hydrolase activity
LI65_RS16315	COG2321	neutral zinc metallopeptidase
LI65_RS16320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LI65_RS16325	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LI65_RS16335	COG2716	regulation of RNA biosynthetic process
LI65_RS16340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LI65_RS16345	COG0628	permease
LI65_RS16350	COG4783	chaperone-mediated protein folding
LI65_RS16355	COG1393	Belongs to the ArsC family
LI65_RS16370	COG1446	asparaginase
LI65_RS16375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI65_RS16385	COG2233	PERMEase
LI65_RS16390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LI65_RS16395	COG2723	6-phospho-beta-galactosidase activity
LI65_RS16405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LI65_RS16420	COG2200	EAL domain
LI65_RS16435	COG3713	MltA-interacting MipA family protein
LI65_RS16440	COG0745	RESPONSE REGULATOR receiver
LI65_RS16460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS16475	COG0517	IMP dehydrogenase activity
LI65_RS16475	COG0516	GMP reductase activity
LI65_RS16480	COG1570	exodeoxyribonuclease VII activity
LI65_RS16495	COG1645	bacterial-type flagellum-dependent swarming motility
LI65_RS16510	COG1160	GTP binding
LI65_RS16520	COG2976	Protein conserved in bacteria
LI65_RS16525	COG0124	histidyl-tRNA synthetase
LI65_RS16540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LI65_RS16560	COG0437	4 iron, 4 sulfur cluster binding
LI65_RS16565	COG0243	molybdopterin cofactor binding
LI65_RS16570	COG4953	penicillin-binding protein 1C
LI65_RS16575	COG2373	Large extracellular alpha-helical protein
LI65_RS16580	COG1263	PTS System
LI65_RS16580	COG2190	(PTS) system
LI65_RS16580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS16590	COG2897	thiosulfate sulfurtransferase activity
LI65_RS16595	COG1737	Transcriptional regulator
LI65_RS16605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI65_RS16610	COG2975	iron-sulfur cluster assembly
LI65_RS16615	COG0633	Ferredoxin
LI65_RS16620	COG0443	Heat shock 70 kDa protein
LI65_RS16625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LI65_RS16630	COG0316	Belongs to the HesB IscA family
LI65_RS16635	COG0822	iron-sulfur transferase activity
LI65_RS16640	COG1104	cysteine desulfurase activity
LI65_RS16660	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LI65_RS16670	COG3711	transcriptional antiterminator
LI65_RS16675	COG2814	Major facilitator Superfamily
LI65_RS16680	COG2259	Doxx family
LI65_RS16695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LI65_RS16695	COG1017	nitric oxide dioxygenase activity
LI65_RS16700	COG0347	Belongs to the P(II) protein family
LI65_RS16705	COG2204	response regulator
LI65_RS16710	COG3170	Tfp pilus assembly protein FimV
LI65_RS16715	COG2205	protein histidine kinase activity
LI65_RS16720	COG0047	phosphoribosylformylglycinamidine synthase activity
LI65_RS16720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LI65_RS16725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LI65_RS16735	COG0560	Phosphoserine phosphatase
LI65_RS16740	COG1263	PTS System
LI65_RS16740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS16745	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LI65_RS16750	COG1737	Transcriptional regulator
LI65_RS16755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI65_RS16765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LI65_RS16770	COG1381	Involved in DNA repair and RecF pathway recombination
LI65_RS16785	COG0681	Belongs to the peptidase S26 family
LI65_RS16850	COG1196	nuclear chromosome segregation
LI65_RS16965	COG3179	chitinase
LI65_RS16985	COG0484	heat shock protein binding
LI65_RS17045	COG1349	DNA-binding transcription factor activity
LI65_RS17060	COG1846	Transcriptional regulator
LI65_RS17100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LI65_RS17135	COG3086	response to oxidative stress
LI65_RS17145	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LI65_RS17155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LI65_RS17160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LI65_RS17165	COG0513	Belongs to the DEAD box helicase family
LI65_RS17170	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LI65_RS17175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LI65_RS17180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LI65_RS17185	COG3118	belongs to the thioredoxin family
LI65_RS17190	COG3148	PFAM DTW domain containing protein
LI65_RS17195	COG0045	succinate-CoA ligase (ADP-forming) activity
LI65_RS17195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS17195	COG1042	CoA-binding domain protein
LI65_RS17200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LI65_RS17205	COG5544	Lipoprotein
LI65_RS17210	COG0477	Major facilitator Superfamily
LI65_RS17240	COG0542	response to heat
LI65_RS17250	COG0564	pseudouridine synthase activity
LI65_RS17255	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS17260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LI65_RS17265	COG1605	Chorismate mutase
LI65_RS17265	COG0077	Prephenate dehydratase
LI65_RS17275	COG0287	Prephenate dehydrogenase
LI65_RS17275	COG1605	Chorismate mutase
LI65_RS17280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LI65_RS17295	COG2199	diguanylate cyclase activity
LI65_RS17300	COG2885	chlorophyll binding
LI65_RS17320	COG0336	Belongs to the RNA methyltransferase TrmD family
LI65_RS17325	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LI65_RS17335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LI65_RS17340	COG4137	Cytochrome C assembly protein
LI65_RS17345	COG4536	flavin adenine dinucleotide binding
LI65_RS17350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LI65_RS17360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LI65_RS17365	COG0497	DNA recombination
LI65_RS17380	COG2867	negative regulation of translational initiation
LI65_RS17390	COG0582	viral genome integration into host DNA
LI65_RS17465	COG3596	GTP binding
LI65_RS17470	COG2378	regulation of single-species biofilm formation
LI65_RS17490	COG2003	Belongs to the UPF0758 family
LI65_RS17515	COG2246	polysaccharide biosynthetic process
LI65_RS17540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS17545	COG4209	transmembrane transport
LI65_RS17550	COG0395	ABC-type sugar transport system, permease component
LI65_RS17565	COG3842	ATPase activity
LI65_RS17570	COG0835	chemotaxis
LI65_RS17580	COG1360	Flagellar Motor Protein
LI65_RS17620	COG1705	Flagellar rod assembly protein muramidase FlgJ
LI65_RS17620	COG3951	Flagellar rod assembly protein muramidase FlgJ
LI65_RS17625	COG1706	bacterial-type flagellum-dependent cell motility
LI65_RS17635	COG4786	Flagellar basal body rod
LI65_RS17645	COG1749	Flagellar hook protein flgE
LI65_RS17660	COG1815	bacterial-type flagellum-dependent cell motility
LI65_RS17670	COG2747	anti-sigma28 factor FlgM
LI65_RS17675	COG3418	PFAM FlgN family protein
LI65_RS17715	COG1987	bacterial-type flagellum assembly
LI65_RS17725	COG3190	flagellar
LI65_RS17730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LI65_RS17740	COG1580	Controls the rotational direction of flagella during chemotaxis
LI65_RS17745	COG3144	bacterial-type flagellum assembly
LI65_RS17770	COG1766	The M ring may be actively involved in energy transduction
LI65_RS17775	COG1677	Flagellar hook-basal body complex protein FliE
LI65_RS17780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LI65_RS17790	COG0745	RESPONSE REGULATOR receiver
LI65_RS17800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LI65_RS17805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LI65_RS17820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LI65_RS17840	COG2814	Major facilitator Superfamily
LI65_RS17845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LI65_RS17850	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS17855	COG1073	alpha beta
LI65_RS17855	COG2226	methyltransferase
LI65_RS17885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS17890	COG3549	Plasmid maintenance system killer
LI65_RS17895	COG3093	addiction module antidote protein HigA
LI65_RS17900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LI65_RS17915	COG2226	methyltransferase
LI65_RS17920	COG0402	S-adenosylhomocysteine deaminase activity
LI65_RS17925	COG0549	Belongs to the carbamate kinase family
LI65_RS17935	COG1304	FMN binding
LI65_RS17940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LI65_RS17945	COG0666	response to abiotic stimulus
LI65_RS17950	COG0583	DNA-binding transcription factor activity
LI65_RS17955	COG0401	homolog of Blt101
LI65_RS17980	COG4575	ribosome binding
LI65_RS17990	COG1780	Probably involved in ribonucleotide reductase function
LI65_RS18005	COG4175	Glycine betaine
LI65_RS18010	COG4176	ABC-type proline glycine betaine transport system permease component
LI65_RS18020	COG2814	Major facilitator Superfamily
LI65_RS18025	COG1846	Transcriptional regulator
LI65_RS18030	COG1566	PFAM secretion protein HlyD family protein
LI65_RS18035	COG2814	Major facilitator Superfamily
LI65_RS18040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LI65_RS18055	COG2918	glutathione biosynthetic process
LI65_RS18060	COG1238	metal cluster binding
LI65_RS18065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS18095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LI65_RS18100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LI65_RS18115	COG1546	Belongs to the CinA family
LI65_RS18125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LI65_RS18135	COG2951	lytic endotransglycosylase activity
LI65_RS18140	COG3730	PTS system glucitol sorbitol-specific
LI65_RS18145	COG3732	PTS system glucitol sorbitol-specific
LI65_RS18155	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS18160	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS18165	COG1349	DNA-binding transcription factor activity
LI65_RS18175	COG3604	Transcriptional regulator
LI65_RS18180	COG1773	rubredoxin
LI65_RS18180	COG0426	domain, Protein
LI65_RS18185	COG0446	pyridine nucleotide-disulphide oxidoreductase
LI65_RS18190	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LI65_RS18195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LI65_RS18200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI65_RS18205	COG1609	Transcriptional regulator
LI65_RS18210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS18210	COG1263	PTS System
LI65_RS18215	COG2723	6-phospho-beta-galactosidase activity
LI65_RS18220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LI65_RS18230	COG3260	NADH ubiquinone oxidoreductase 20
LI65_RS18235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LI65_RS18240	COG3261	NADH dehydrogenase
LI65_RS18240	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LI65_RS18245	COG0650	Formate hydrogenlyase subunit 4
LI65_RS18250	COG0651	ATP synthesis coupled electron transport
LI65_RS18255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI65_RS18265	COG0375	protein maturation
LI65_RS18270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LI65_RS18275	COG0298	carbon dioxide binding
LI65_RS18280	COG0409	Hydrogenase expression formation protein
LI65_RS18285	COG0309	Hydrogenase expression formation protein (HypE)
LI65_RS18305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LI65_RS18315	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LI65_RS18320	COG0163	prenyltransferase activity
LI65_RS18335	COG0477	Major facilitator Superfamily
LI65_RS18350	COG1388	LysM domain
LI65_RS18350	COG4942	peptidase
LI65_RS18365	COG0585	pseudouridine synthase activity
LI65_RS18370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LI65_RS18375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LI65_RS18380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LI65_RS18390	COG0529	Catalyzes the synthesis of activated sulfate
LI65_RS18410	COG2234	aminopeptidase activity
LI65_RS18425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LI65_RS18430	COG0720	synthase
LI65_RS18440	COG1473	amidohydrolase
LI65_RS18450	COG0602	queuosine metabolic process
LI65_RS18455	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LI65_RS18460	COG2190	(PTS) system
LI65_RS18460	COG1263	PTS System
LI65_RS18460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS18465	COG1737	Transcriptional regulator
LI65_RS18480	COG3956	TIGRFAM MazG family protein
LI65_RS18485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LI65_RS18490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI65_RS18495	COG4999	Histidine kinase
LI65_RS18495	COG3850	Histidine kinase
LI65_RS18495	COG3437	response regulator, receiver
LI65_RS18495	COG2205	protein histidine kinase activity
LI65_RS18500	COG1929	Belongs to the glycerate kinase type-1 family
LI65_RS18505	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS18510	COG4948	Mandelate Racemase Muconate Lactonizing
LI65_RS18515	COG2271	Major facilitator Superfamily
LI65_RS18520	COG0716	FMN binding
LI65_RS18525	COG0564	pseudouridine synthase activity
LI65_RS18530	COG3098	single-species biofilm formation
LI65_RS18550	COG1611	Belongs to the LOG family
LI65_RS18555	COG0814	amino acid
LI65_RS18560	COG1760	l-serine dehydratase
LI65_RS18570	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LI65_RS18575	COG2363	Small membrane protein
LI65_RS18580	COG0583	DNA-binding transcription factor activity
LI65_RS18590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LI65_RS18595	COG2166	iron-sulfur cluster assembly
LI65_RS18600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LI65_RS18605	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LI65_RS18625	COG0860	N-Acetylmuramoyl-L-alanine amidase
LI65_RS18630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LI65_RS18630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LI65_RS18635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LI65_RS18640	COG1074	ATP-dependent DNA helicase activity
LI65_RS18650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LI65_RS18655	COG4967	type IV pilus modification protein PilV
LI65_RS18665	COG4795	General secretion pathway protein
LI65_RS18670	COG2165	general secretion pathway protein
LI65_RS18675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LI65_RS18680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LI65_RS18690	COG0494	nUDIX hydrolase
LI65_RS18695	COG3066	DNA modification
LI65_RS18705	COG0667	Aldo Keto reductase
LI65_RS18710	COG0477	Major facilitator Superfamily
LI65_RS18715	COG0204	Acyl-transferase
LI65_RS18715	COG0318	PFAM AMP-dependent synthetase and ligase
LI65_RS18720	COG1609	Transcriptional regulator
LI65_RS18730	COG2186	Transcriptional regulator
LI65_RS18740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LI65_RS18745	COG1609	Transcriptional regulator
LI65_RS18755	COG0583	DNA-binding transcription factor activity
LI65_RS18760	COG1794	racemase activity, acting on amino acids and derivatives
LI65_RS18770	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LI65_RS18775	COG1175	transmembrane transport
LI65_RS18780	COG0395	ABC-type sugar transport system, permease component
LI65_RS18785	COG3842	ATPase activity
LI65_RS18795	COG2814	Major facilitator Superfamily
LI65_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS18805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LI65_RS18810	COG0823	Involved in the tonB-independent uptake of proteins
LI65_RS18815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI65_RS18820	COG0183	Belongs to the thiolase family
LI65_RS18835	COG0814	amino acid
LI65_RS18840	COG2388	GCN5-related N-acetyl-transferase
LI65_RS18845	COG3592	Divergent 4Fe-4S mono-cluster
LI65_RS18850	COG3729	General stress protein
LI65_RS18855	COG3685	Protein conserved in bacteria
LI65_RS18860	COG3685	Protein conserved in bacteria
LI65_RS18865	COG3546	catalase activity
LI65_RS18870	COG1271	oxidase subunit
LI65_RS18875	COG1294	oxidase, subunit
LI65_RS18890	COG1546	Belongs to the CinA family
LI65_RS18905	COG3111	PFAM Bacterial OB fold (BOF) protein
LI65_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS18915	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LI65_RS18935	COG2067	long-chain fatty acid transport protein
LI65_RS18940	COG1335	isochorismatase
LI65_RS18960	COG4942	peptidase
LI65_RS18965	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LI65_RS18970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LI65_RS18985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LI65_RS18995	COG4974	Belongs to the 'phage' integrase family
LI65_RS19010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LI65_RS19015	COG0354	folic acid binding
LI65_RS19020	COG1272	protein, Hemolysin III
LI65_RS19025	COG1737	Transcriptional regulator
LI65_RS19030	COG2723	6-phospho-beta-galactosidase activity
LI65_RS19050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LI65_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS19060	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LI65_RS19060	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LI65_RS19070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LI65_RS19075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI65_RS19080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LI65_RS19085	COG0006	proline dipeptidase activity
LI65_RS19095	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LI65_RS19100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LI65_RS19105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LI65_RS19110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LI65_RS19115	COG0583	DNA-binding transcription factor activity
LI65_RS19120	COG2968	Membrane
LI65_RS19125	COG1279	arginine transmembrane transporter activity
LI65_RS19130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LI65_RS19135	COG0668	transmembrane transport
LI65_RS19140	COG0191	fructose-bisphosphate aldolase activity
LI65_RS19145	COG0126	phosphoglycerate kinase activity
LI65_RS19150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LI65_RS19155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LI65_RS19160	COG0501	Belongs to the peptidase M48B family
LI65_RS19180	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LI65_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS19190	COG2267	carboxylic ester hydrolase activity
LI65_RS19215	COG1414	Transcriptional regulator
LI65_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS19235	COG2146	nitrite reductase [NAD(P)H] activity
LI65_RS19245	COG0010	Belongs to the arginase family
LI65_RS19250	COG1166	arginine decarboxylase activity
LI65_RS19265	COG2814	Major facilitator Superfamily
LI65_RS19270	COG3091	SprT-like family
LI65_RS19275	COG2356	endonuclease I
LI65_RS19280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LI65_RS19300	COG2805	Type II/IV secretion system protein
LI65_RS19305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LI65_RS19310	COG0762	integral membrane protein
LI65_RS19315	COG1872	DUF167
LI65_RS19325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LI65_RS19330	COG2852	Protein conserved in bacteria
LI65_RS19340	COG3171	Protein conserved in bacteria
LI65_RS19350	COG1194	a g-specific adenine glycosylase
LI65_RS19360	COG0741	lytic transglycosylase activity
LI65_RS19365	COG2211	Major facilitator Superfamily
LI65_RS19370	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LI65_RS19390	COG3052	prosthetic group binding
LI65_RS19400	COG0179	Fumarylacetoacetate (FAA) hydrolase
LI65_RS19405	COG3493	citrate carrier protein
LI65_RS19420	COG1982	Orn Lys Arg decarboxylase major
LI65_RS19425	COG1811	Na channel or pump
LI65_RS19435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LI65_RS19435	COG2205	protein histidine kinase activity
LI65_RS19440	COG2197	response regulator
LI65_RS19460	COG0457	Tetratricopeptide repeat
LI65_RS19465	COG0726	polysaccharide deacetylase
LI65_RS19465	COG1649	PFAM Uncharacterised BCR, COG1649
LI65_RS19470	COG1215	transferase activity, transferring glycosyl groups
LI65_RS19480	COG0754	glutathionylspermidine amidase activity
LI65_RS19485	COG0625	glutathione transferase activity
LI65_RS19490	COG1349	DNA-binding transcription factor activity
LI65_RS19495	COG0840	transmembrane signaling receptor activity
LI65_RS19500	COG0667	Aldo Keto reductase
LI65_RS19505	COG2862	Uncharacterized protein family, UPF0114
LI65_RS19525	COG0848	biopolymer transport protein
LI65_RS19535	COG0626	cystathionine gamma-synthase activity
LI65_RS19540	COG0586	Pfam SNARE associated Golgi protein
LI65_RS19545	COG2207	Transcriptional regulator
LI65_RS19550	COG1979	alcohol dehydrogenase
LI65_RS19560	COG1032	radical SAM domain protein
LI65_RS19580	COG3111	PFAM Bacterial OB fold (BOF) protein
LI65_RS19595	COG2249	NAD(P)H dehydrogenase (quinone) activity
LI65_RS19600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LI65_RS19605	COG1652	LysM domain
LI65_RS19610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LI65_RS19615	COG2211	Major facilitator Superfamily
LI65_RS19640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS19645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LI65_RS19650	COG1120	ATPase activity
LI65_RS19655	COG4774	siderophore transport
LI65_RS19660	COG0187	DNA topoisomerase II activity
LI65_RS19665	COG3150	esterase
LI65_RS19670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LI65_RS19675	COG3151	Protein conserved in bacteria
LI65_RS19680	COG0494	nUDIX hydrolase
LI65_RS19695	COG0754	glutathionylspermidine amidase activity
LI65_RS19700	COG3384	dioxygenase
LI65_RS19710	COG3539	Fimbrial protein
LI65_RS19715	COG3188	usher protein
LI65_RS19720	COG3121	Chaperone
LI65_RS19725	COG3539	Fimbrial protein
LI65_RS19730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LI65_RS19740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LI65_RS19740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LI65_RS19750	COG3025	triphosphatase activity
LI65_RS19755	COG4991	sh3 domain protein
LI65_RS19760	COG0617	tRNA 3'-terminal CCA addition
LI65_RS19770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LI65_RS19780	COG0477	Major facilitator Superfamily
LI65_RS19785	COG0829	nickel cation binding
LI65_RS19790	COG0831	urea catabolic process
LI65_RS19795	COG0832	Belongs to the urease beta subunit family
LI65_RS19800	COG0804	urea catabolic process
LI65_RS19805	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LI65_RS19815	COG0830	nickel cation binding
LI65_RS19820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LI65_RS19830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LI65_RS19835	COG0358	DNA primase activity
LI65_RS19845	COG3663	DNA glycosylase
LI65_RS19910	COG2375	cellular response to nickel ion
LI65_RS19915	COG1695	Transcriptional regulator
LI65_RS19920	COG0840	transmembrane signaling receptor activity
LI65_RS19925	COG0840	transmembrane signaling receptor activity
LI65_RS19930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LI65_RS19945	COG3121	Chaperone
LI65_RS19950	COG3188	usher protein
LI65_RS19960	COG3539	Fimbrial protein
LI65_RS19970	COG3121	Chaperone
LI65_RS19985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LI65_RS19990	COG1830	Aldolase
LI65_RS19995	COG1879	ABC-type sugar transport system periplasmic component
LI65_RS20000	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS20005	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS20010	COG1129	ABC transporter
LI65_RS20015	COG2390	Transcriptional regulator
LI65_RS20020	COG1070	Carbohydrate kinase
LI65_RS20025	COG1902	pentaerythritol trinitrate reductase activity
LI65_RS20025	COG0446	pyridine nucleotide-disulphide oxidoreductase
LI65_RS20035	COG1451	nucleotide metabolic process
LI65_RS20040	COG0673	inositol 2-dehydrogenase activity
LI65_RS20045	COG0861	Integral membrane protein TerC family
LI65_RS20055	COG2721	sulfolactate sulfo-lyase activity
LI65_RS20065	COG2271	Major facilitator Superfamily
LI65_RS20070	COG2186	Transcriptional regulator
LI65_RS20075	COG0586	Pfam SNARE associated Golgi protein
LI65_RS20085	COG1422	Protein of unknown function (DUF1090)
LI65_RS20090	COG4575	ribosome binding
LI65_RS20095	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LI65_RS20105	COG2259	Doxx family
LI65_RS20110	COG0435	Glutathione S-transferase
LI65_RS20115	COG3152	Membrane
LI65_RS20120	COG0583	DNA-binding transcription factor activity
LI65_RS20125	COG1741	Belongs to the pirin family
LI65_RS20135	COG0814	amino acid
LI65_RS20140	COG1882	Formate acetyltransferase
LI65_RS20145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LI65_RS20150	COG0814	amino acid
LI65_RS20155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LI65_RS20160	COG0583	DNA-binding transcription factor activity
LI65_RS20165	COG1929	Belongs to the glycerate kinase type-1 family
LI65_RS20170	COG2084	Dehydrogenase
LI65_RS20180	COG2721	sulfolactate sulfo-lyase activity
LI65_RS20185	COG1349	DNA-binding transcription factor activity
LI65_RS20195	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS20205	COG3716	PTS system mannose fructose sorbose family IID component
LI65_RS20210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS20215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LI65_RS20220	COG2222	sugar isomerase
LI65_RS20225	COG0191	fructose-bisphosphate aldolase activity
LI65_RS20230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LI65_RS20230	COG1263	PTS System
LI65_RS20245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LI65_RS20250	COG3107	peptidoglycan biosynthetic process
LI65_RS20255	COG0792	nuclease activity
LI65_RS20260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LI65_RS20265	COG2823	Periplasmic or secreted lipoprotein
LI65_RS20270	COG0701	Predicted permease
LI65_RS20275	COG0702	epimerase
LI65_RS20280	COG0693	protein deglycase activity
LI65_RS20285	COG3787	Belongs to the UPF0306 family
LI65_RS20290	COG2827	Endonuclease containing a URI domain
LI65_RS20295	COG3153	acetyltransferase
LI65_RS20300	COG3154	lipid carrier protein
LI65_RS20305	COG0826	peptidase U32
LI65_RS20310	COG0826	peptidase U32
LI65_RS20315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LI65_RS20320	COG0814	amino acid
LI65_RS20325	COG0513	Belongs to the DEAD box helicase family
LI65_RS20340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LI65_RS20345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LI65_RS20350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LI65_RS20355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LI65_RS20375	COG0137	argininosuccinate synthase activity
LI65_RS20385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LI65_RS20390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LI65_RS20395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LI65_RS20405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LI65_RS20410	COG1534	Rna-binding protein
LI65_RS20420	COG2027	D-alanyl-D-alanine carboxypeptidase
LI65_RS20425	COG0745	RESPONSE REGULATOR receiver
LI65_RS20430	COG0642	Histidine kinase
LI65_RS20435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LI65_RS20440	COG0697	spore germination
LI65_RS20450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LI65_RS20455	COG0142	geranyltranstransferase activity
LI65_RS20460	COG3423	Transcriptional regulator
LI65_RS20465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LI65_RS20470	COG5007	Belongs to the BolA IbaG family
LI65_RS20475	COG3113	response to antibiotic
LI65_RS20480	COG2854	intermembrane phospholipid transfer
LI65_RS20485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LI65_RS20490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LI65_RS20495	COG1127	ABC transporter
LI65_RS20500	COG0530	calcium, potassium:sodium antiporter activity
LI65_RS20510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LI65_RS20515	COG3117	lipopolysaccharide transmembrane transporter activity
LI65_RS20520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LI65_RS20525	COG1137	ATPase activity
LI65_RS20530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LI65_RS20550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS20560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LI65_RS20565	COG0784	Response regulator, receiver
LI65_RS20565	COG2198	Histidine kinase
LI65_RS20565	COG5002	protein histidine kinase activity
LI65_RS20570	COG0795	lipopolysaccharide-transporting ATPase activity
LI65_RS20575	COG0795	lipopolysaccharide-transporting ATPase activity
LI65_RS20580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LI65_RS20585	COG2927	DNA polymerase III (CHI subunit)
LI65_RS20595	COG0456	acetyltransferase
LI65_RS20600	COG1064	alcohol dehydrogenase
LI65_RS20610	COG0433	COG0433 Predicted ATPase
LI65_RS20615	COG1242	4 iron, 4 sulfur cluster binding
LI65_RS20620	COG0070	glutamate synthase
LI65_RS20620	COG0069	glutamate synthase activity
LI65_RS20620	COG0067	glutamate synthase
LI65_RS20625	COG0493	'glutamate synthase
LI65_RS20630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LI65_RS20635	COG0402	S-adenosylhomocysteine deaminase activity
LI65_RS20640	COG2731	YhcH YjgK YiaL family protein
LI65_RS20655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LI65_RS20660	COG2186	Transcriptional regulator
LI65_RS20665	COG2969	positive regulation of protein catabolic process
LI65_RS20670	COG0625	glutathione transferase activity
LI65_RS20680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LI65_RS20690	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LI65_RS20695	COG3105	Protein conserved in bacteria
LI65_RS20700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LI65_RS20705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LI65_RS20715	COG1438	arginine binding
LI65_RS20725	COG2732	(Barnase) inhibitor
LI65_RS20730	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS20735	COG1289	transmembrane transporter activity
LI65_RS20750	COG0583	DNA-binding transcription factor activity
LI65_RS20755	COG0312	modulator of DNA gyrase
LI65_RS20760	COG3164	Protein of unknown function
LI65_RS20775	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LI65_RS20780	COG1792	Involved in formation and maintenance of cell shape
LI65_RS20785	COG1077	Cell shape determining protein MreB Mrl
LI65_RS20790	COG2200	EAL domain
LI65_RS20790	COG2199	diguanylate cyclase activity
LI65_RS20795	COG0604	alcohol dehydrogenase
LI65_RS20805	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LI65_RS20810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LI65_RS20815	COG0511	ligase activity, forming carbon-carbon bonds
LI65_RS20820	COG0439	Biotin carboxylase
LI65_RS20825	COG3924	membrane
LI65_RS20830	COG4145	pantothenate transmembrane transporter activity
LI65_RS20835	COG2264	protein methyltransferase activity
LI65_RS20865	COG1309	transcriptional regulator
LI65_RS20870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LI65_RS20875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LI65_RS20915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LI65_RS20925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LI65_RS20930	COG0009	L-threonylcarbamoyladenylate synthase
LI65_RS20935	COG0551	DNA topoisomerase type I activity
LI65_RS20940	COG2922	Belongs to the Smg family
LI65_RS20945	COG0758	DNA mediated transformation
LI65_RS20950	COG0242	peptide deformylase activity
LI65_RS20955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LI65_RS20960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LI65_RS20960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LI65_RS20970	COG1970	mechanosensitive ion channel activity
LI65_RS20975	COG3036	rescue of stalled ribosome
LI65_RS20980	COG0789	Transcriptional regulator
LI65_RS20995	COG0202	RNA polymerase activity
LI65_RS21005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LI65_RS21020	COG0201	protein transport
LI65_RS21030	COG1841	ribosomal large subunit assembly
LI65_RS21045	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LI65_RS21050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LI65_RS21080	COG0255	Belongs to the universal ribosomal protein uL29 family
LI65_RS21085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LI65_RS21125	COG0051	transcription antitermination factor activity, RNA binding
LI65_RS21165	COG2168	tRNA wobble position uridine thiolation
LI65_RS21170	COG2923	Belongs to the DsrF TusC family
LI65_RS21175	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LI65_RS21180	COG2964	Protein conserved in bacteria
LI65_RS21185	COG0545	Peptidyl-prolyl cis-trans isomerase
LI65_RS21195	COG1047	Peptidyl-prolyl cis-trans
LI65_RS21200	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LI65_RS21205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LI65_RS21205	COG0475	glutathione-regulated potassium exporter activity
LI65_RS21210	COG2249	NAD(P)H dehydrogenase (quinone) activity
LI65_RS21215	COG0488	(ABC) transporter
LI65_RS21225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LI65_RS21235	COG0679	Auxin Efflux Carrier
LI65_RS21270	COG0429	hydrolase of the alpha beta-hydrolase fold
LI65_RS21275	COG3089	Belongs to the UPF0270 family
LI65_RS21280	COG3954	Phosphoribulokinase
LI65_RS21285	COG1765	OsmC-like protein
LI65_RS21295	COG1289	transmembrane transporter activity
LI65_RS21300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LI65_RS21305	COG0512	Glutamine amidotransferase of anthranilate synthase
LI65_RS21310	COG2184	nucleotidyltransferase activity
LI65_RS21320	COG0738	Major facilitator superfamily
LI65_RS21325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LI65_RS21335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LI65_RS21335	COG1648	precorrin-2 dehydrogenase activity
LI65_RS21345	COG0180	Tryptophanyl-tRNA synthetase
LI65_RS21355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LI65_RS21360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LI65_RS21365	COG3266	domain, Protein
LI65_RS21370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LI65_RS21375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LI65_RS21385	COG4796	Type ii and iii secretion system protein
LI65_RS21405	COG4972	Pilus assembly protein
LI65_RS21410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LI65_RS21415	COG0494	nUDIX hydrolase
LI65_RS21430	COG1011	Hydrolase
LI65_RS21435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LI65_RS21440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LI65_RS21445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LI65_RS21460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LI65_RS21465	COG2183	response to ionizing radiation
LI65_RS21470	COG1918	ferrous iron import across plasma membrane
LI65_RS21490	COG1040	competence protein
LI65_RS21500	COG2610	gluconate transmembrane transporter activity
LI65_RS21505	COG1640	4-alpha-glucanotransferase
LI65_RS21510	COG0058	SHG alpha-glucan phosphorylase activity
LI65_RS21515	COG2909	trisaccharide binding
LI65_RS21520	COG1349	DNA-binding transcription factor activity
LI65_RS21525	COG0705	Rhomboid family
LI65_RS21530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LI65_RS21540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LI65_RS21545	COG0058	SHG alpha-glucan phosphorylase activity
LI65_RS21550	COG0297	glycogen (starch) synthase activity
LI65_RS21555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LI65_RS21560	COG1523	belongs to the glycosyl hydrolase 13 family
LI65_RS21565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LI65_RS21570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LI65_RS21580	COG2095	MarC family integral membrane protein
LI65_RS21585	COG2610	gluconate transmembrane transporter activity
LI65_RS21590	COG3265	gluconokinase activity
LI65_RS21595	COG1609	Transcriptional regulator
LI65_RS21600	COG1741	Belongs to the pirin family
LI65_RS21605	COG0673	inositol 2-dehydrogenase activity
LI65_RS21610	COG1247	-acetyltransferase
LI65_RS21615	COG0405	Gamma-glutamyltransferase
LI65_RS21625	COG0584	glycerophosphoryl diester phosphodiesterase
LI65_RS21655	COG0411	ABC transporter
LI65_RS21660	COG4177	L-phenylalanine transmembrane transporter activity
LI65_RS21670	COG0683	leucine binding
LI65_RS21685	COG0456	acetyltransferase
LI65_RS21690	COG0683	leucine binding
LI65_RS21695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LI65_RS21700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LI65_RS21705	COG2177	Part of the ABC transporter FtsEX involved in
LI65_RS21710	COG2884	Cell division ATP-binding protein ftsE
LI65_RS21715	COG0552	protein localization to endoplasmic reticulum
LI65_RS21720	COG0742	ribosomal rna small subunit methyltransferase
LI65_RS21725	COG3776	membrane
LI65_RS21735	COG3714	YhhN family
LI65_RS21755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LI65_RS21760	COG0425	Belongs to the sulfur carrier protein TusA family
LI65_RS21765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LI65_RS21775	COG0628	permease
LI65_RS21795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LI65_RS21815	COG1216	Glycosyl transferase, family 2
LI65_RS21840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI65_RS21850	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS21855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LI65_RS21900	COG3479	Phenolic acid decarboxylase
LI65_RS21905	COG0583	DNA-binding transcription factor activity
LI65_RS21910	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS21925	COG2081	HI0933 family
LI65_RS21930	COG0306	phosphate transporter
LI65_RS21940	COG0589	response to stress
LI65_RS21945	COG0742	ribosomal rna small subunit methyltransferase
LI65_RS21950	COG0339	signal peptide processing
LI65_RS21955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LI65_RS21960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LI65_RS21980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LI65_RS21990	COG2197	response regulator
LI65_RS21995	COG1028	Short-chain dehydrogenase reductase Sdr
LI65_RS22000	COG0583	DNA-binding transcription factor activity
LI65_RS22005	COG1295	ribonuclease BN
LI65_RS22010	COG0477	Major facilitator Superfamily
LI65_RS22015	COG2982	Protein involved in outer membrane biogenesis
LI65_RS22020	COG2200	EAL domain
LI65_RS22030	COG0612	Peptidase, M16
LI65_RS22035	COG1301	dicarboxylic acid transport
LI65_RS22040	COG2200	EAL domain
LI65_RS22040	COG2199	diguanylate cyclase activity
LI65_RS22045	COG3118	belongs to the thioredoxin family
LI65_RS22045	COG0457	Tetratricopeptide repeat
LI65_RS22050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LI65_RS22055	COG1215	transferase activity, transferring glycosyl groups
LI65_RS22085	COG2194	sulfuric ester hydrolase activity
LI65_RS22095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LI65_RS22130	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LI65_RS22140	COG1739	Uncharacterized protein family UPF0029
LI65_RS22145	COG0006	proline dipeptidase activity
LI65_RS22150	COG1250	3-hydroxyacyl-CoA dehydrogenase
LI65_RS22150	COG1024	Enoyl-CoA hydratase
LI65_RS22155	COG0183	Belongs to the thiolase family
LI65_RS22160	COG0751	glycine-tRNA ligase activity
LI65_RS22165	COG0752	glycyl-tRNA synthetase alpha subunit
LI65_RS22175	COG3274	enterobacterial common antigen metabolic process
LI65_RS22180	COG1070	Carbohydrate kinase
LI65_RS22185	COG2115	Belongs to the xylose isomerase family
LI65_RS22190	COG4213	ABC transporter substrate-binding protein
LI65_RS22200	COG4214	carbohydrate transport
LI65_RS22205	COG1609	Transcriptional regulator
LI65_RS22205	COG2207	Transcriptional regulator
LI65_RS22210	COG2992	FlgJ-related protein
LI65_RS22215	COG0366	Alpha amylase catalytic
LI65_RS22220	COG3977	Valine--pyruvate aminotransferase
LI65_RS22225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LI65_RS22230	COG1414	Transcriptional regulator
LI65_RS22240	COG2731	YhcH YjgK YiaL family protein
LI65_RS22250	COG2271	Major facilitator Superfamily
LI65_RS22255	COG1070	Carbohydrate kinase
LI65_RS22260	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LI65_RS22265	COG3623	hexulose-6-phosphate isomerase
LI65_RS22270	COG0235	Class ii aldolase
LI65_RS22280	COG2211	Major facilitator Superfamily
LI65_RS22290	COG1012	belongs to the aldehyde dehydrogenase family
LI65_RS22295	COG1940	carbohydrate kinase activity
LI65_RS22300	COG3276	selenocysteine insertion sequence binding
LI65_RS22310	COG0625	glutathione transferase activity
LI65_RS22315	COG2213	PTS system mannitol-specific
LI65_RS22315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LI65_RS22325	COG3722	fumarate hydratase activity
LI65_RS22345	COG3121	Chaperone
LI65_RS22350	COG3539	Fimbrial protein
LI65_RS22360	COG2186	Transcriptional regulator
LI65_RS22365	COG1304	FMN binding
LI65_RS22370	COG2271	Major facilitator Superfamily
LI65_RS22375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LI65_RS22385	COG0583	DNA-binding transcription factor activity
LI65_RS22390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LI65_RS22400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LI65_RS22405	COG3978	acetolactate synthase activity
LI65_RS22420	COG3085	chromosome segregation
LI65_RS22470	COG4206	TonB-dependent receptor
LI65_RS22475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LI65_RS22495	COG0583	DNA-binding transcription factor activity
LI65_RS22500	COG0165	Argininosuccinate lyase
LI65_RS22510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LI65_RS22515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LI65_RS22520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LI65_RS22530	COG0371	Dehydrogenase
LI65_RS22535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LI65_RS22545	COG0527	aspartate kinase activity
LI65_RS22545	COG0460	homoserine dehydrogenase
LI65_RS22550	COG0626	cystathionine gamma-synthase activity
LI65_RS22560	COG0254	rRNA binding
LI65_RS22565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LI65_RS22570	COG1609	Transcriptional regulator
LI65_RS22575	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LI65_RS22590	COG1575	Belongs to the MenA family. Type 1 subfamily
LI65_RS22605	COG3074	FtsZ-dependent cytokinesis
LI65_RS22610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LI65_RS22620	COG1494	fructose-1,6-bisphosphatase
LI65_RS22630	COG3152	Membrane
LI65_RS22640	COG0149	triose-phosphate isomerase activity
LI65_RS22650	COG2134	cdp-diacylglycerol pyrophosphatase
LI65_RS22660	COG0205	6-phosphofructokinase activity
LI65_RS22670	COG3678	ATP-independent chaperone mediated protein folding
LI65_RS22675	COG0745	RESPONSE REGULATOR receiver
LI65_RS22680	COG2205	protein histidine kinase activity
LI65_RS22685	COG2258	MOSC domain
LI65_RS22690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LI65_RS22705	COG4977	sequence-specific DNA binding
LI65_RS22715	COG1070	Carbohydrate kinase
LI65_RS22720	COG4806	L-rhamnose isomerase
LI65_RS22725	COG0235	Class ii aldolase
LI65_RS22735	COG1129	ABC transporter
LI65_RS22740	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS22750	COG1454	alcohol dehydrogenase
LI65_RS22760	COG2211	Major facilitator Superfamily
LI65_RS22780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LI65_RS22795	COG3188	usher protein
LI65_RS22800	COG3121	Chaperone
LI65_RS22820	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS22820	COG0243	molybdopterin cofactor binding
LI65_RS22825	COG3383	formate dehydrogenase (NAD+) activity
LI65_RS22825	COG0243	molybdopterin cofactor binding
LI65_RS22830	COG0437	4 iron, 4 sulfur cluster binding
LI65_RS22835	COG2864	formate dehydrogenase
LI65_RS22840	COG3058	Necessary for formate dehydrogenase activity
LI65_RS22850	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LI65_RS22860	COG0456	acetyltransferase
LI65_RS22875	COG1011	Hydrolase
LI65_RS22880	COG1349	DNA-binding transcription factor activity
LI65_RS22885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS22895	COG3684	Belongs to the aldolase LacD family
LI65_RS22905	COG1501	Belongs to the glycosyl hydrolase 31 family
LI65_RS22920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LI65_RS22935	COG3852	Histidine kinase
LI65_RS22950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LI65_RS22955	COG3078	GTPase activator activity
LI65_RS22970	COG0204	Acyl-transferase
LI65_RS22980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LI65_RS22985	COG3084	Protein conserved in bacteria
LI65_RS22990	COG0746	molybdenum cofactor guanylyltransferase activity
LI65_RS22995	COG1763	Mo-molybdopterin cofactor biosynthetic process
LI65_RS23020	COG2186	Transcriptional regulator
LI65_RS23025	COG0477	Major facilitator Superfamily
LI65_RS23030	COG1609	Transcriptional regulator
LI65_RS23035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LI65_RS23045	COG1172	Belongs to the binding-protein-dependent transport system permease family
LI65_RS23050	COG1129	ABC transporter
LI65_RS23055	COG1869	D-ribose catabolic process
LI65_RS23060	COG3158	transport of potassium into the cell
LI65_RS23070	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LI65_RS23075	COG2502	aspartate--ammonia ligase
LI65_RS23080	COG1522	sequence-specific DNA binding
LI65_RS23085	COG0716	FMN binding
LI65_RS23090	COG0445	tRNA wobble uridine modification
LI65_RS23095	COG0357	Ribosomal RNA small subunit methyltransferase G
LI65_RS23100	COG3312	ion transport
LI65_RS23105	COG0356	it plays a direct role in the translocation of protons across the membrane
LI65_RS23115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LI65_RS23120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LI65_RS23135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LI65_RS23140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LI65_RS23145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LI65_RS23155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LI65_RS23160	COG0573	inorganic phosphate transmembrane transporter activity
LI65_RS23165	COG0581	inorganic phosphate transmembrane transporter activity
LI65_RS23170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LI65_RS23175	COG0704	Plays a role in the regulation of phosphate uptake
LI65_RS23180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LI65_RS23185	COG2252	PERMEase
LI65_RS23190	COG0431	NADPH-dependent FMN reductase
LI65_RS23195	COG2091	lysine biosynthetic process via aminoadipic acid
LI65_RS23215	COG0706	membrane insertase activity
LI65_RS23305	COG2186	Transcriptional regulator
LI65_RS23315	COG3734	2-keto-3-deoxy-galactonokinase
LI65_RS23845	COG1501	Belongs to the glycosyl hydrolase 31 family
LI65_RS23965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS24045	COG2003	Belongs to the UPF0758 family
LI65_RS24155	COG0463	Glycosyl transferase, family 2
LI65_RS24180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LI65_RS24295	COG2959	enzyme of heme biosynthesis
LI65_RS24360	COG0514	ATP-dependent DNA helicase (RecQ)
LI65_RS24435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LI65_RS24580	COG0187	DNA topoisomerase II activity
LI65_RS24775	COG2271	Major facilitator Superfamily
LI65_RS25075	COG3272	Protein of unknown function (DUF1722)
LI65_RS25200	COG1501	Belongs to the glycosyl hydrolase 31 family
LI65_RS25360	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LI65_RS25370	COG0489	protein tyrosine kinase activity
LI65_RS25370	COG3206	protein involved in exopolysaccharide biosynthesis
LI65_RS25385	COG3206	protein involved in exopolysaccharide biosynthesis
LI65_RS25385	COG0489	protein tyrosine kinase activity
LI65_RS25570	COG0210	DNA helicase
LI65_RS25630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LI65_RS25720	COG0181	hydroxymethylbilane synthase activity