locus-tag	class	description
CUN65_RS00010	COG0592	DNA-directed DNA polymerase activity
CUN65_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CUN65_RS00025	COG0583	DNA-binding transcription factor activity
CUN65_RS00030	COG0604	alcohol dehydrogenase
CUN65_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS00030	COG3321	synthase
CUN65_RS00035	COG0561	phosphatase activity
CUN65_RS00040	COG2186	Transcriptional regulator
CUN65_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
CUN65_RS00050	COG0800	Aldolase
CUN65_RS00055	COG4948	Mandelate Racemase Muconate Lactonizing
CUN65_RS00060	COG2271	Major facilitator Superfamily
CUN65_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
CUN65_RS00070	COG5645	(Lipo)protein
CUN65_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
CUN65_RS00085	COG2985	domain, Protein
CUN65_RS00090	COG2188	Transcriptional regulator
CUN65_RS00105	COG2149	membrane
CUN65_RS00120	COG2610	gluconate transmembrane transporter activity
CUN65_RS00125	COG0583	DNA-binding transcription factor activity
CUN65_RS00135	COG2814	Major facilitator Superfamily
CUN65_RS00175	COG0028	Belongs to the TPP enzyme family
CUN65_RS00180	COG0440	acetolactate synthase activity
CUN65_RS00185	COG2197	response regulator
CUN65_RS00205	COG0596	Alpha beta hydrolase
CUN65_RS00230	COG0697	spore germination
CUN65_RS00235	COG4580	involved in the transport of maltose and maltodextrins
CUN65_RS00240	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUN65_RS00245	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS00250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS00250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS00260	COG1609	Transcriptional regulator
CUN65_RS00270	COG2814	Major facilitator Superfamily
CUN65_RS00280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS00285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS00295	COG0454	-acetyltransferase
CUN65_RS00300	COG1309	transcriptional regulator
CUN65_RS00310	COG1464	Belongs to the NlpA lipoprotein family
CUN65_RS00335	COG3188	usher protein
CUN65_RS00340	COG3121	Chaperone
CUN65_RS00370	COG3188	usher protein
CUN65_RS00395	COG2274	protein secretion by the type I secretion system
CUN65_RS00410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CUN65_RS00415	COG4977	sequence-specific DNA binding
CUN65_RS00435	COG3272	Protein of unknown function (DUF1722)
CUN65_RS00440	COG2351	hydroxyisourate hydrolase activity
CUN65_RS00445	COG0789	Transcriptional regulator
CUN65_RS00470	COG3121	Chaperone
CUN65_RS00500	COG0519	Catalyzes the synthesis of GMP from XMP
CUN65_RS00545	COG2211	Major facilitator Superfamily
CUN65_RS00550	COG1501	Belongs to the glycosyl hydrolase 31 family
CUN65_RS00555	COG2982	Protein involved in outer membrane biogenesis
CUN65_RS00560	COG2233	PERMEase
CUN65_RS00565	COG0786	glutamate:sodium symporter activity
CUN65_RS00570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUN65_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUN65_RS00580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUN65_RS00595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CUN65_RS00615	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUN65_RS00620	COG1596	polysaccharide export
CUN65_RS00625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUN65_RS00630	COG3206	protein involved in exopolysaccharide biosynthesis
CUN65_RS00630	COG0489	protein tyrosine kinase activity
CUN65_RS00635	COG2860	membrane
CUN65_RS00640	COG1561	YicC-like family, N-terminal region
CUN65_RS00650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CUN65_RS00660	COG0756	dUTP diphosphatase activity
CUN65_RS00665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUN65_RS00670	COG2003	Belongs to the UPF0758 family
CUN65_RS00675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CUN65_RS00680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUN65_RS00685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CUN65_RS00690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CUN65_RS00700	COG1519	Transferase
CUN65_RS00705	COG1216	Glycosyl transferase, family 2
CUN65_RS00710	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS00720	COG0859	PFAM glycosyl transferase family 9
CUN65_RS00745	COG0859	PFAM glycosyl transferase family 9
CUN65_RS00750	COG0859	PFAM glycosyl transferase family 9
CUN65_RS00765	COG1063	alcohol dehydrogenase
CUN65_RS00775	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS00780	COG0463	Glycosyl transferase, family 2
CUN65_RS00785	COG2861	carbohydrate metabolic process
CUN65_RS00790	COG4942	peptidase
CUN65_RS00795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CUN65_RS00800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUN65_RS00805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUN65_RS00810	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CUN65_RS00815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CUN65_RS00825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUN65_RS00835	COG0248	Ppx GppA phosphatase
CUN65_RS00845	COG3118	belongs to the thioredoxin family
CUN65_RS00850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CUN65_RS00855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUN65_RS00865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUN65_RS00870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CUN65_RS00875	COG0456	acetyltransferase
CUN65_RS00880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUN65_RS00885	COG2244	polysaccharide biosynthetic process
CUN65_RS00900	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CUN65_RS00935	COG3071	HemY protein
CUN65_RS00940	COG2959	enzyme of heme biosynthesis
CUN65_RS00950	COG0181	hydroxymethylbilane synthase activity
CUN65_RS00970	COG5567	small periplasmic lipoprotein
CUN65_RS00990	COG1011	Hydrolase
CUN65_RS00995	COG0210	DNA helicase
CUN65_RS01020	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CUN65_RS01030	COG1280	lysine exporter protein (LysE YggA)
CUN65_RS01040	COG2267	carboxylic ester hydrolase activity
CUN65_RS01045	COG0561	phosphatase activity
CUN65_RS01050	COG0697	spore germination
CUN65_RS01055	COG0583	DNA-binding transcription factor activity
CUN65_RS01065	COG0412	Dienelactone hydrolase
CUN65_RS01075	COG1322	Protein conserved in bacteria
CUN65_RS01080	COG2226	methyltransferase
CUN65_RS01085	COG3165	ubiquinone biosynthetic process from chorismate
CUN65_RS01090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CUN65_RS01105	COG0805	protein transport
CUN65_RS01110	COG0084	hydrolase, TatD family'
CUN65_RS01120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CUN65_RS01130	COG0488	(ABC) transporter
CUN65_RS01135	COG2944	sequence-specific DNA binding
CUN65_RS01145	COG1278	Cold shock
CUN65_RS01150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUN65_RS01160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUN65_RS01170	COG1609	Transcriptional regulator
CUN65_RS01175	COG2885	chlorophyll binding
CUN65_RS01180	COG0243	molybdopterin cofactor binding
CUN65_RS01185	COG0456	acetyltransferase
CUN65_RS01190	COG2818	Glycosylase
CUN65_RS01195	COG5571	outer membrane autotransporter
CUN65_RS01200	COG2223	nitrite transmembrane transporter activity
CUN65_RS01215	COG0747	negative chemotaxis
CUN65_RS01220	COG0601	transmembrane transport
CUN65_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUN65_RS01230	COG0444	Belongs to the ABC transporter superfamily
CUN65_RS01235	COG4608	Belongs to the ABC transporter superfamily
CUN65_RS01240	COG1072	(Pantothenic acid kinase))
CUN65_RS01275	COG0250	Participates in transcription elongation, termination and antitermination
CUN65_RS01325	COG3706	GGDEF domain
CUN65_RS01335	COG2022	thiamine diphosphate biosynthetic process
CUN65_RS01340	COG2104	thiamine diphosphate biosynthetic process
CUN65_RS01345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CUN65_RS01360	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CUN65_RS01370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CUN65_RS01375	COG1515	deoxyribonuclease V activity
CUN65_RS01380	COG3068	Protein conserved in bacteria
CUN65_RS01395	COG0151	Belongs to the GarS family
CUN65_RS01430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CUN65_RS01440	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CUN65_RS01460	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUN65_RS01465	COG3657	addiction module killer protein
CUN65_RS01470	COG1187	pseudouridine synthase activity
CUN65_RS01485	COG0527	aspartate kinase activity
CUN65_RS01510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUN65_RS01515	COG3223	Belongs to the PsiE family
CUN65_RS01545	COG4580	involved in the transport of maltose and maltodextrins
CUN65_RS01555	COG3161	chorismate lyase activity
CUN65_RS01565	COG2937	Belongs to the GPAT DAPAT family
CUN65_RS01570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CUN65_RS01575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUN65_RS01580	COG0534	Mate efflux family protein
CUN65_RS01585	COG3237	CsbD-like
CUN65_RS01590	COG0735	belongs to the Fur family
CUN65_RS01605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUN65_RS01615	COG0604	alcohol dehydrogenase
CUN65_RS01620	COG0305	Participates in initiation and elongation during chromosome replication
CUN65_RS01630	COG1448	Aminotransferase
CUN65_RS01635	COG3700	Belongs to the class B bacterial acid phosphatase family
CUN65_RS01645	COG2315	Protein conserved in bacteria
CUN65_RS01660	COG0629	single-stranded DNA binding
CUN65_RS01670	COG2199	diguanylate cyclase activity
CUN65_RS01675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CUN65_RS01685	COG0789	Transcriptional regulator
CUN65_RS01690	COG0625	glutathione transferase activity
CUN65_RS01695	COG2252	PERMEase
CUN65_RS01700	COG0025	NhaP-type Na H and K H
CUN65_RS01705	COG0583	DNA-binding transcription factor activity
CUN65_RS01715	COG1346	cytolysis
CUN65_RS01720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUN65_RS01725	COG3162	membrane
CUN65_RS01735	COG1301	dicarboxylic acid transport
CUN65_RS01740	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CUN65_RS01765	COG0191	fructose-bisphosphate aldolase activity
CUN65_RS01780	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS01785	COG1129	ABC transporter
CUN65_RS01790	COG4191	Histidine kinase
CUN65_RS01790	COG0784	Response regulator, receiver
CUN65_RS01800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CUN65_RS01805	COG0456	acetyltransferase
CUN65_RS01810	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CUN65_RS01815	COG3454	Phosphonate metabolism
CUN65_RS01820	COG4778	phosphonate C-P lyase system protein PhnL
CUN65_RS01825	COG4107	phosphonate C-P lyase system protein PhnK
CUN65_RS01830	COG3627	carbon phosphorus lyase activity
CUN65_RS01835	COG3626	phosphonate metabolism
CUN65_RS01840	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CUN65_RS01845	COG3624	Phosphonate C-P lyase system protein PhnG
CUN65_RS01850	COG2188	Transcriptional regulator
CUN65_RS01855	COG3639	organic phosphonate transmembrane transporter activity
CUN65_RS01860	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CUN65_RS01870	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CUN65_RS01875	COG2824	Alkylphosphonate utilization operon protein PhnA
CUN65_RS01880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CUN65_RS01900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CUN65_RS01940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS01945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS01950	COG1309	transcriptional regulator
CUN65_RS01985	COG4145	pantothenate transmembrane transporter activity
CUN65_RS01990	COG3924	membrane
CUN65_RS01995	COG0439	Biotin carboxylase
CUN65_RS02000	COG0511	ligase activity, forming carbon-carbon bonds
CUN65_RS02005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CUN65_RS02010	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CUN65_RS02020	COG0604	alcohol dehydrogenase
CUN65_RS02025	COG2200	EAL domain
CUN65_RS02025	COG2199	diguanylate cyclase activity
CUN65_RS02030	COG1077	Cell shape determining protein MreB Mrl
CUN65_RS02035	COG1792	Involved in formation and maintenance of cell shape
CUN65_RS02040	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CUN65_RS02055	COG3164	Protein of unknown function
CUN65_RS02060	COG0312	modulator of DNA gyrase
CUN65_RS02065	COG0583	DNA-binding transcription factor activity
CUN65_RS02080	COG1289	transmembrane transporter activity
CUN65_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS02090	COG2732	(Barnase) inhibitor
CUN65_RS02100	COG1438	arginine binding
CUN65_RS02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUN65_RS02115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUN65_RS02120	COG3105	Protein conserved in bacteria
CUN65_RS02125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CUN65_RS02135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CUN65_RS02140	COG0625	glutathione transferase activity
CUN65_RS02145	COG2969	positive regulation of protein catabolic process
CUN65_RS02150	COG3539	Fimbrial protein
CUN65_RS02155	COG3121	Chaperone
CUN65_RS02160	COG3188	usher protein
CUN65_RS02170	COG3539	Fimbrial protein
CUN65_RS02175	COG3539	Fimbrial protein
CUN65_RS02180	COG0493	'glutamate synthase
CUN65_RS02185	COG0070	glutamate synthase
CUN65_RS02185	COG0067	glutamate synthase
CUN65_RS02185	COG0069	glutamate synthase activity
CUN65_RS02190	COG1242	4 iron, 4 sulfur cluster binding
CUN65_RS02195	COG0433	COG0433 Predicted ATPase
CUN65_RS02205	COG1064	alcohol dehydrogenase
CUN65_RS02210	COG0456	acetyltransferase
CUN65_RS02220	COG2927	DNA polymerase III (CHI subunit)
CUN65_RS02225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CUN65_RS02230	COG0795	lipopolysaccharide-transporting ATPase activity
CUN65_RS02235	COG0795	lipopolysaccharide-transporting ATPase activity
CUN65_RS02240	COG5002	protein histidine kinase activity
CUN65_RS02240	COG2198	Histidine kinase
CUN65_RS02240	COG0784	Response regulator, receiver
CUN65_RS02245	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CUN65_RS02255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS02275	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CUN65_RS02280	COG1137	ATPase activity
CUN65_RS02285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CUN65_RS02290	COG3117	lipopolysaccharide transmembrane transporter activity
CUN65_RS02295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CUN65_RS02305	COG0530	calcium, potassium:sodium antiporter activity
CUN65_RS02315	COG1127	ABC transporter
CUN65_RS02320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CUN65_RS02325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CUN65_RS02330	COG2854	intermembrane phospholipid transfer
CUN65_RS02335	COG3113	response to antibiotic
CUN65_RS02340	COG5007	Belongs to the BolA IbaG family
CUN65_RS02345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUN65_RS02350	COG3423	Transcriptional regulator
CUN65_RS02355	COG0142	geranyltranstransferase activity
CUN65_RS02360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CUN65_RS02370	COG0697	spore germination
CUN65_RS02375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CUN65_RS02380	COG0642	Histidine kinase
CUN65_RS02385	COG0745	RESPONSE REGULATOR receiver
CUN65_RS02390	COG2027	D-alanyl-D-alanine carboxypeptidase
CUN65_RS02400	COG1534	Rna-binding protein
CUN65_RS02405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CUN65_RS02415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CUN65_RS02420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUN65_RS02425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CUN65_RS02435	COG0137	argininosuccinate synthase activity
CUN65_RS02455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CUN65_RS02460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CUN65_RS02465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUN65_RS02470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CUN65_RS02490	COG0513	Belongs to the DEAD box helicase family
CUN65_RS02495	COG0814	amino acid
CUN65_RS02500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS02505	COG0826	peptidase U32
CUN65_RS02510	COG0826	peptidase U32
CUN65_RS02515	COG3154	lipid carrier protein
CUN65_RS02520	COG3153	acetyltransferase
CUN65_RS02525	COG2827	Endonuclease containing a URI domain
CUN65_RS02530	COG3787	Belongs to the UPF0306 family
CUN65_RS02535	COG0693	protein deglycase activity
CUN65_RS02540	COG0702	epimerase
CUN65_RS02545	COG0701	Predicted permease
CUN65_RS02550	COG2823	Periplasmic or secreted lipoprotein
CUN65_RS02555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CUN65_RS02560	COG0792	nuclease activity
CUN65_RS02565	COG3107	peptidoglycan biosynthetic process
CUN65_RS02575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CUN65_RS02590	COG1263	PTS System
CUN65_RS02590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS02595	COG0191	fructose-bisphosphate aldolase activity
CUN65_RS02600	COG2222	sugar isomerase
CUN65_RS02605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CUN65_RS02610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS02615	COG3716	PTS system mannose fructose sorbose family IID component
CUN65_RS02625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS02635	COG1349	DNA-binding transcription factor activity
CUN65_RS02640	COG2721	sulfolactate sulfo-lyase activity
CUN65_RS02650	COG2084	Dehydrogenase
CUN65_RS02655	COG1929	Belongs to the glycerate kinase type-1 family
CUN65_RS02665	COG0583	DNA-binding transcription factor activity
CUN65_RS02670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUN65_RS02675	COG0814	amino acid
CUN65_RS02680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CUN65_RS02685	COG1882	Formate acetyltransferase
CUN65_RS02690	COG0814	amino acid
CUN65_RS02700	COG1741	Belongs to the pirin family
CUN65_RS02705	COG0583	DNA-binding transcription factor activity
CUN65_RS02710	COG3152	Membrane
CUN65_RS02715	COG0435	Glutathione S-transferase
CUN65_RS02720	COG2259	Doxx family
CUN65_RS02730	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CUN65_RS02735	COG4575	ribosome binding
CUN65_RS02740	COG1422	Protein of unknown function (DUF1090)
CUN65_RS02750	COG0586	Pfam SNARE associated Golgi protein
CUN65_RS02755	COG2186	Transcriptional regulator
CUN65_RS02765	COG2271	Major facilitator Superfamily
CUN65_RS02775	COG2721	sulfolactate sulfo-lyase activity
CUN65_RS02785	COG0861	Integral membrane protein TerC family
CUN65_RS02790	COG0673	inositol 2-dehydrogenase activity
CUN65_RS02795	COG1451	nucleotide metabolic process
CUN65_RS02805	COG1902	pentaerythritol trinitrate reductase activity
CUN65_RS02805	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUN65_RS02810	COG1070	Carbohydrate kinase
CUN65_RS02815	COG2390	Transcriptional regulator
CUN65_RS02820	COG1129	ABC transporter
CUN65_RS02825	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS02830	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS02835	COG1879	ABC-type sugar transport system periplasmic component
CUN65_RS02840	COG1830	Aldolase
CUN65_RS02845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CUN65_RS02860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUN65_RS02865	COG0840	transmembrane signaling receptor activity
CUN65_RS02870	COG0840	transmembrane signaling receptor activity
CUN65_RS02875	COG1695	Transcriptional regulator
CUN65_RS02880	COG2375	cellular response to nickel ion
CUN65_RS02905	COG4974	Belongs to the 'phage' integrase family
CUN65_RS02975	COG4695	Portal protein
CUN65_RS03065	COG5301	cellulose 1,4-beta-cellobiosidase activity
CUN65_RS03115	COG0582	viral genome integration into host DNA
CUN65_RS03150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUN65_RS03205	COG4695	Portal protein
CUN65_RS03305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CUN65_RS03360	COG3663	DNA glycosylase
CUN65_RS03370	COG0358	DNA primase activity
CUN65_RS03375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CUN65_RS03390	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CUN65_RS03395	COG0830	nickel cation binding
CUN65_RS03405	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CUN65_RS03410	COG0804	urea catabolic process
CUN65_RS03415	COG0832	Belongs to the urease beta subunit family
CUN65_RS03420	COG0831	urea catabolic process
CUN65_RS03425	COG0829	nickel cation binding
CUN65_RS03430	COG0477	Major facilitator Superfamily
CUN65_RS03440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CUN65_RS03450	COG0617	tRNA 3'-terminal CCA addition
CUN65_RS03455	COG4991	sh3 domain protein
CUN65_RS03460	COG3025	triphosphatase activity
CUN65_RS03470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CUN65_RS03470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CUN65_RS03480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUN65_RS03485	COG3539	Fimbrial protein
CUN65_RS03490	COG3121	Chaperone
CUN65_RS03495	COG3188	usher protein
CUN65_RS03500	COG3539	Fimbrial protein
CUN65_RS03510	COG3384	dioxygenase
CUN65_RS03515	COG0754	glutathionylspermidine amidase activity
CUN65_RS03530	COG0494	nUDIX hydrolase
CUN65_RS03535	COG3151	Protein conserved in bacteria
CUN65_RS03540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CUN65_RS03545	COG3150	esterase
CUN65_RS03550	COG0187	DNA topoisomerase II activity
CUN65_RS03565	COG2211	Major facilitator Superfamily
CUN65_RS03570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CUN65_RS03580	COG1652	LysM domain
CUN65_RS03585	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CUN65_RS03590	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUN65_RS03605	COG3111	PFAM Bacterial OB fold (BOF) protein
CUN65_RS03625	COG1032	radical SAM domain protein
CUN65_RS03635	COG1979	alcohol dehydrogenase
CUN65_RS03640	COG2207	Transcriptional regulator
CUN65_RS03645	COG0586	Pfam SNARE associated Golgi protein
CUN65_RS03650	COG0626	cystathionine gamma-synthase activity
CUN65_RS03665	COG0848	biopolymer transport protein
CUN65_RS03685	COG2862	Uncharacterized protein family, UPF0114
CUN65_RS03690	COG0667	Aldo Keto reductase
CUN65_RS03695	COG0840	transmembrane signaling receptor activity
CUN65_RS03705	COG0625	glutathione transferase activity
CUN65_RS03710	COG0754	glutathionylspermidine amidase activity
CUN65_RS03720	COG1215	transferase activity, transferring glycosyl groups
CUN65_RS03725	COG0726	polysaccharide deacetylase
CUN65_RS03725	COG1649	PFAM Uncharacterised BCR, COG1649
CUN65_RS03730	COG0457	Tetratricopeptide repeat
CUN65_RS03750	COG2197	response regulator
CUN65_RS03755	COG5002	protein histidine kinase activity
CUN65_RS03765	COG1811	Na channel or pump
CUN65_RS03770	COG1982	Orn Lys Arg decarboxylase major
CUN65_RS03785	COG3493	citrate carrier protein
CUN65_RS03790	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUN65_RS03800	COG3052	prosthetic group binding
CUN65_RS03820	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CUN65_RS03825	COG2211	Major facilitator Superfamily
CUN65_RS03830	COG0741	lytic transglycosylase activity
CUN65_RS03840	COG1194	a g-specific adenine glycosylase
CUN65_RS03850	COG3171	Protein conserved in bacteria
CUN65_RS03860	COG2852	Protein conserved in bacteria
CUN65_RS03865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUN65_RS03875	COG1872	DUF167
CUN65_RS03880	COG0762	integral membrane protein
CUN65_RS03885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CUN65_RS03890	COG2805	Type II/IV secretion system protein
CUN65_RS03910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUN65_RS03915	COG2356	endonuclease I
CUN65_RS03920	COG3091	SprT-like family
CUN65_RS03925	COG2814	Major facilitator Superfamily
CUN65_RS03945	COG1166	arginine decarboxylase activity
CUN65_RS03950	COG0010	Belongs to the arginase family
CUN65_RS03960	COG2146	nitrite reductase [NAD(P)H] activity
CUN65_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS03980	COG1414	Transcriptional regulator
CUN65_RS04005	COG2267	carboxylic ester hydrolase activity
CUN65_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS04015	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CUN65_RS04030	COG0501	Belongs to the peptidase M48B family
CUN65_RS04035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUN65_RS04040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CUN65_RS04045	COG0126	phosphoglycerate kinase activity
CUN65_RS04050	COG0191	fructose-bisphosphate aldolase activity
CUN65_RS04055	COG0668	transmembrane transport
CUN65_RS04060	COG1279	arginine transmembrane transporter activity
CUN65_RS04065	COG2968	Membrane
CUN65_RS04070	COG0583	DNA-binding transcription factor activity
CUN65_RS04075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CUN65_RS04085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUN65_RS04090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUN65_RS04100	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CUN65_RS04110	COG0006	proline dipeptidase activity
CUN65_RS04115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUN65_RS04120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUN65_RS04125	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CUN65_RS04135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUN65_RS04135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUN65_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS04145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUN65_RS04165	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS04170	COG1737	Transcriptional regulator
CUN65_RS04175	COG1272	protein, Hemolysin III
CUN65_RS04180	COG0354	folic acid binding
CUN65_RS04185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CUN65_RS04200	COG4974	Belongs to the 'phage' integrase family
CUN65_RS04210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUN65_RS04220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CUN65_RS04225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CUN65_RS04230	COG4942	peptidase
CUN65_RS04250	COG1335	isochorismatase
CUN65_RS04275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CUN65_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS04285	COG3111	PFAM Bacterial OB fold (BOF) protein
CUN65_RS04300	COG1546	Belongs to the CinA family
CUN65_RS04315	COG1294	oxidase, subunit
CUN65_RS04320	COG1271	oxidase subunit
CUN65_RS04325	COG3546	catalase activity
CUN65_RS04330	COG3685	Protein conserved in bacteria
CUN65_RS04335	COG3685	Protein conserved in bacteria
CUN65_RS04340	COG3729	General stress protein
CUN65_RS04345	COG3592	Divergent 4Fe-4S mono-cluster
CUN65_RS04350	COG2388	GCN5-related N-acetyl-transferase
CUN65_RS04355	COG0814	amino acid
CUN65_RS04370	COG0183	Belongs to the thiolase family
CUN65_RS04380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CUN65_RS04385	COG0823	Involved in the tonB-independent uptake of proteins
CUN65_RS04390	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CUN65_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS04400	COG2814	Major facilitator Superfamily
CUN65_RS04410	COG3842	ATPase activity
CUN65_RS04415	COG0395	ABC-type sugar transport system, permease component
CUN65_RS04420	COG1175	transmembrane transport
CUN65_RS04430	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CUN65_RS04440	COG1794	racemase activity, acting on amino acids and derivatives
CUN65_RS04445	COG0583	DNA-binding transcription factor activity
CUN65_RS04455	COG1609	Transcriptional regulator
CUN65_RS04460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS04465	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS04470	COG2186	Transcriptional regulator
CUN65_RS04480	COG1609	Transcriptional regulator
CUN65_RS04485	COG0204	Acyl-transferase
CUN65_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
CUN65_RS04490	COG0477	Major facilitator Superfamily
CUN65_RS04495	COG0667	Aldo Keto reductase
CUN65_RS04505	COG3066	DNA modification
CUN65_RS04510	COG0494	nUDIX hydrolase
CUN65_RS04520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CUN65_RS04525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CUN65_RS04530	COG2165	general secretion pathway protein
CUN65_RS04535	COG4795	General secretion pathway protein
CUN65_RS04545	COG4967	type IV pilus modification protein PilV
CUN65_RS04550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CUN65_RS04560	COG1074	ATP-dependent DNA helicase activity
CUN65_RS04565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUN65_RS04570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CUN65_RS04570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CUN65_RS04575	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUN65_RS04600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CUN65_RS04605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CUN65_RS04610	COG2166	iron-sulfur cluster assembly
CUN65_RS04615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUN65_RS04625	COG0583	DNA-binding transcription factor activity
CUN65_RS04630	COG2363	Small membrane protein
CUN65_RS04635	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CUN65_RS04645	COG1760	l-serine dehydratase
CUN65_RS04650	COG0814	amino acid
CUN65_RS04655	COG1611	Belongs to the LOG family
CUN65_RS04670	COG3098	single-species biofilm formation
CUN65_RS04675	COG0564	pseudouridine synthase activity
CUN65_RS04680	COG0716	FMN binding
CUN65_RS04690	COG2271	Major facilitator Superfamily
CUN65_RS04695	COG4948	Mandelate Racemase Muconate Lactonizing
CUN65_RS04705	COG1929	Belongs to the glycerate kinase type-1 family
CUN65_RS04710	COG3437	response regulator, receiver
CUN65_RS04710	COG3850	Histidine kinase
CUN65_RS04710	COG4999	Histidine kinase
CUN65_RS04710	COG2205	protein histidine kinase activity
CUN65_RS04715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUN65_RS04720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUN65_RS04725	COG3956	TIGRFAM MazG family protein
CUN65_RS04740	COG1737	Transcriptional regulator
CUN65_RS04745	COG2190	(PTS) system
CUN65_RS04745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS04745	COG1263	PTS System
CUN65_RS04750	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CUN65_RS04755	COG0602	queuosine metabolic process
CUN65_RS04765	COG1473	amidohydrolase
CUN65_RS04775	COG0720	synthase
CUN65_RS04780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CUN65_RS04795	COG2234	aminopeptidase activity
CUN65_RS04815	COG0529	Catalyzes the synthesis of activated sulfate
CUN65_RS04825	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CUN65_RS04830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CUN65_RS04835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CUN65_RS04840	COG0585	pseudouridine synthase activity
CUN65_RS04855	COG1388	LysM domain
CUN65_RS04855	COG4942	peptidase
CUN65_RS04870	COG0477	Major facilitator Superfamily
CUN65_RS04885	COG0163	prenyltransferase activity
CUN65_RS04890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CUN65_RS04900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CUN65_RS04905	COG3710	Transcriptional regulator
CUN65_RS04930	COG1120	ATPase activity
CUN65_RS04935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS04950	COG0309	Hydrogenase expression formation protein (HypE)
CUN65_RS04955	COG0409	Hydrogenase expression formation protein
CUN65_RS04960	COG0298	carbon dioxide binding
CUN65_RS04965	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CUN65_RS04970	COG0375	protein maturation
CUN65_RS04985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUN65_RS04990	COG0651	ATP synthesis coupled electron transport
CUN65_RS04995	COG0650	Formate hydrogenlyase subunit 4
CUN65_RS05000	COG3261	NADH dehydrogenase
CUN65_RS05000	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CUN65_RS05005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUN65_RS05010	COG3260	NADH ubiquinone oxidoreductase 20
CUN65_RS05020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CUN65_RS05025	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS05030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS05030	COG1263	PTS System
CUN65_RS05035	COG1609	Transcriptional regulator
CUN65_RS05040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUN65_RS05045	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CUN65_RS05050	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CUN65_RS05055	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUN65_RS05060	COG0426	domain, Protein
CUN65_RS05060	COG1773	rubredoxin
CUN65_RS05065	COG3604	Transcriptional regulator
CUN65_RS05075	COG1349	DNA-binding transcription factor activity
CUN65_RS05080	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS05095	COG3732	PTS system glucitol sorbitol-specific
CUN65_RS05100	COG3730	PTS system glucitol sorbitol-specific
CUN65_RS05105	COG2951	lytic endotransglycosylase activity
CUN65_RS05115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUN65_RS05125	COG1546	Belongs to the CinA family
CUN65_RS05140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CUN65_RS05145	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CUN65_RS05175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUN65_RS05180	COG1238	metal cluster binding
CUN65_RS05185	COG2918	glutathione biosynthetic process
CUN65_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUN65_RS05205	COG2814	Major facilitator Superfamily
CUN65_RS05210	COG1566	PFAM secretion protein HlyD family protein
CUN65_RS05215	COG1846	Transcriptional regulator
CUN65_RS05220	COG2814	Major facilitator Superfamily
CUN65_RS05230	COG4176	ABC-type proline glycine betaine transport system permease component
CUN65_RS05235	COG4175	Glycine betaine
CUN65_RS05245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUN65_RS05250	COG1780	Probably involved in ribonucleotide reductase function
CUN65_RS05260	COG4575	ribosome binding
CUN65_RS05285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUN65_RS05290	COG0401	homolog of Blt101
CUN65_RS05295	COG0583	DNA-binding transcription factor activity
CUN65_RS05300	COG0666	response to abiotic stimulus
CUN65_RS05305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CUN65_RS05310	COG1304	FMN binding
CUN65_RS05320	COG0549	Belongs to the carbamate kinase family
CUN65_RS05325	COG0402	S-adenosylhomocysteine deaminase activity
CUN65_RS05340	COG0740	serine-type endopeptidase activity
CUN65_RS05470	COG2867	negative regulation of translational initiation
CUN65_RS05490	COG0497	DNA recombination
CUN65_RS05495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUN65_RS05500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CUN65_RS05505	COG4536	flavin adenine dinucleotide binding
CUN65_RS05510	COG4137	Cytochrome C assembly protein
CUN65_RS05515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUN65_RS05525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CUN65_RS05530	COG0336	Belongs to the RNA methyltransferase TrmD family
CUN65_RS05585	COG5301	cellulose 1,4-beta-cellobiosidase activity
CUN65_RS05585	COG5301	cellulose 1,4-beta-cellobiosidase activity
CUN65_RS05670	COG4695	Portal protein
CUN65_RS05730	COG4974	Belongs to the 'phage' integrase family
CUN65_RS05745	COG2885	chlorophyll binding
CUN65_RS05750	COG2199	diguanylate cyclase activity
CUN65_RS05765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUN65_RS05770	COG1605	Chorismate mutase
CUN65_RS05770	COG0287	Prephenate dehydrogenase
CUN65_RS05780	COG0077	Prephenate dehydratase
CUN65_RS05780	COG1605	Chorismate mutase
CUN65_RS05790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CUN65_RS05795	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUN65_RS05800	COG0564	pseudouridine synthase activity
CUN65_RS05810	COG0542	response to heat
CUN65_RS05840	COG0477	Major facilitator Superfamily
CUN65_RS05845	COG5544	Lipoprotein
CUN65_RS05850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUN65_RS05855	COG1042	CoA-binding domain protein
CUN65_RS05855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS05855	COG0045	succinate-CoA ligase (ADP-forming) activity
CUN65_RS05860	COG3148	PFAM DTW domain containing protein
CUN65_RS05865	COG3118	belongs to the thioredoxin family
CUN65_RS05875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUN65_RS05880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CUN65_RS05885	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CUN65_RS05890	COG0513	Belongs to the DEAD box helicase family
CUN65_RS05895	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CUN65_RS05900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CUN65_RS05910	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CUN65_RS05920	COG3086	response to oxidative stress
CUN65_RS05930	COG0681	Belongs to the peptidase S26 family
CUN65_RS05945	COG1381	Involved in DNA repair and RecF pathway recombination
CUN65_RS05950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CUN65_RS05960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUN65_RS05965	COG1737	Transcriptional regulator
CUN65_RS05970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CUN65_RS05975	COG1263	PTS System
CUN65_RS05975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS05980	COG0560	Phosphoserine phosphatase
CUN65_RS05990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CUN65_RS05995	COG0047	phosphoribosylformylglycinamidine synthase activity
CUN65_RS05995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUN65_RS06000	COG2205	protein histidine kinase activity
CUN65_RS06005	COG3170	Tfp pilus assembly protein FimV
CUN65_RS06010	COG2204	response regulator
CUN65_RS06015	COG0347	Belongs to the P(II) protein family
CUN65_RS06020	COG1017	nitric oxide dioxygenase activity
CUN65_RS06020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUN65_RS06035	COG2259	Doxx family
CUN65_RS06040	COG2814	Major facilitator Superfamily
CUN65_RS06045	COG3711	transcriptional antiterminator
CUN65_RS06055	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CUN65_RS06075	COG1104	cysteine desulfurase activity
CUN65_RS06080	COG0822	iron-sulfur transferase activity
CUN65_RS06085	COG0316	Belongs to the HesB IscA family
CUN65_RS06090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CUN65_RS06095	COG0443	Heat shock 70 kDa protein
CUN65_RS06100	COG0633	Ferredoxin
CUN65_RS06105	COG2975	iron-sulfur cluster assembly
CUN65_RS06110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CUN65_RS06120	COG1737	Transcriptional regulator
CUN65_RS06125	COG2897	thiosulfate sulfurtransferase activity
CUN65_RS06135	COG1263	PTS System
CUN65_RS06135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS06135	COG2190	(PTS) system
CUN65_RS06140	COG2373	Large extracellular alpha-helical protein
CUN65_RS06145	COG4953	penicillin-binding protein 1C
CUN65_RS06150	COG0243	molybdopterin cofactor binding
CUN65_RS06155	COG0437	4 iron, 4 sulfur cluster binding
CUN65_RS06175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CUN65_RS06180	COG1426	Protein conserved in bacteria
CUN65_RS06185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CUN65_RS06190	COG0124	histidyl-tRNA synthetase
CUN65_RS06195	COG2976	Protein conserved in bacteria
CUN65_RS06205	COG1160	GTP binding
CUN65_RS06215	COG1645	bacterial-type flagellum-dependent swarming motility
CUN65_RS06230	COG1570	exodeoxyribonuclease VII activity
CUN65_RS06235	COG0517	IMP dehydrogenase activity
CUN65_RS06235	COG0516	GMP reductase activity
CUN65_RS06245	COG3708	Transcriptional regulator
CUN65_RS06245	COG2207	Transcriptional regulator
CUN65_RS06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS06270	COG0745	RESPONSE REGULATOR receiver
CUN65_RS06275	COG3713	MltA-interacting MipA family protein
CUN65_RS06295	COG0583	DNA-binding transcription factor activity
CUN65_RS06305	COG2200	EAL domain
CUN65_RS06320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUN65_RS06330	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS06340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CUN65_RS06345	COG2233	PERMEase
CUN65_RS06355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CUN65_RS06360	COG1446	asparaginase
CUN65_RS06375	COG1393	Belongs to the ArsC family
CUN65_RS06380	COG4783	chaperone-mediated protein folding
CUN65_RS06385	COG0628	permease
CUN65_RS06390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CUN65_RS06395	COG2716	regulation of RNA biosynthetic process
CUN65_RS06405	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CUN65_RS06410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CUN65_RS06415	COG2321	neutral zinc metallopeptidase
CUN65_RS06420	COG1444	tRNA N-acetyltransferase activity
CUN65_RS06425	COG0400	carboxylic ester hydrolase activity
CUN65_RS06435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUN65_RS06440	COG1393	Belongs to the ArsC family
CUN65_RS06450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS06455	COG3850	Histidine kinase
CUN65_RS06465	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUN65_RS06465	COG0493	'glutamate synthase
CUN65_RS06470	COG0494	nUDIX hydrolase
CUN65_RS06475	COG5342	invasion associated locus B
CUN65_RS06480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUN65_RS06495	COG0408	coproporphyrinogen oxidase activity
CUN65_RS06500	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUN65_RS06520	COG2837	iron assimilation
CUN65_RS06525	COG4150	thiosulfate binding
CUN65_RS06530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CUN65_RS06535	COG4208	sulfate ABC transporter
CUN65_RS06540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CUN65_RS06565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS06595	COG3115	cell septum assembly
CUN65_RS06600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CUN65_RS06605	COG3530	Putative quorum-sensing-regulated virulence factor
CUN65_RS06610	COG0385	Bile acid
CUN65_RS06615	COG0583	DNA-binding transcription factor activity
CUN65_RS06650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUN65_RS06655	COG3415	Transposase
CUN65_RS06660	COG3415	Transposase
CUN65_RS06675	COG2199	diguanylate cyclase activity
CUN65_RS06675	COG2200	EAL domain
CUN65_RS06680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUN65_RS06685	COG1914	H( )-stimulated, divalent metal cation uptake system
CUN65_RS06695	COG0667	Aldo Keto reductase
CUN65_RS06700	COG3961	Belongs to the TPP enzyme family
CUN65_RS06710	COG0837	glucose binding
CUN65_RS06715	COG3279	Response regulator of the LytR AlgR family
CUN65_RS06720	COG3275	phosphorelay sensor kinase activity
CUN65_RS06725	COG0436	Aminotransferase
CUN65_RS06735	COG1560	Kdo2-lipid A biosynthetic process
CUN65_RS06740	COG3706	GGDEF domain
CUN65_RS06750	COG2116	formate transmembrane transporter activity
CUN65_RS06760	COG2067	long-chain fatty acid transport protein
CUN65_RS06765	COG3691	Protein conserved in bacteria
CUN65_RS06775	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUN65_RS06775	COG1024	Enoyl-CoA hydratase
CUN65_RS06780	COG2062	phosphohistidine phosphatase, SixA
CUN65_RS06785	COG2840	Smr protein MutS2
CUN65_RS06795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CUN65_RS06805	COG0730	response to heat
CUN65_RS06810	COG3101	peptidyl-lysine hydroxylation
CUN65_RS06820	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CUN65_RS06820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUN65_RS06825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS06840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUN65_RS06845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CUN65_RS06850	COG0101	tRNA pseudouridine synthase activity
CUN65_RS06855	COG0586	Pfam SNARE associated Golgi protein
CUN65_RS06865	COG0285	dihydrofolate synthase activity
CUN65_RS06870	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CUN65_RS06875	COG1286	toxin biosynthetic process
CUN65_RS06880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CUN65_RS06885	COG0163	prenyltransferase activity
CUN65_RS06895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS06905	COG4160	amino acid transport
CUN65_RS06910	COG4598	ABC transporter
CUN65_RS06915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS06920	COG1090	epimerase
CUN65_RS06925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CUN65_RS06930	COG0625	glutathione transferase activity
CUN65_RS06935	COG0625	glutathione transferase activity
CUN65_RS06940	COG0622	Phosphoesterase
CUN65_RS06950	COG1609	Transcriptional regulator
CUN65_RS06955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS06965	COG3037	sugar-specific permease SgaT UlaA
CUN65_RS06970	COG3959	Transketolase, thiamine diphosphate binding domain
CUN65_RS06975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUN65_RS07000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUN65_RS07005	COG0471	metal ion transport
CUN65_RS07005	COG0490	domain, Protein
CUN65_RS07015	COG0436	Aminotransferase
CUN65_RS07020	COG0583	DNA-binding transcription factor activity
CUN65_RS07030	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUN65_RS07060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CUN65_RS07070	COG0839	Belongs to the complex I subunit 6 family
CUN65_RS07075	COG0713	ATP synthesis coupled electron transport
CUN65_RS07080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUN65_RS07085	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUN65_RS07090	COG1007	ATP synthesis coupled electron transport
CUN65_RS07095	COG0784	Response regulator, receiver
CUN65_RS07095	COG0835	chemotaxis
CUN65_RS07100	COG1234	tRNA 3'-trailer cleavage
CUN65_RS07105	COG2153	protein acetylation
CUN65_RS07110	COG4575	ribosome binding
CUN65_RS07115	COG1169	isochorismate synthase
CUN65_RS07120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CUN65_RS07125	COG0596	Alpha beta hydrolase
CUN65_RS07135	COG1441	menaquinone biosynthetic process
CUN65_RS07180	COG0247	lactate metabolic process
CUN65_RS07185	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CUN65_RS07190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CUN65_RS07200	COG2271	Major facilitator Superfamily
CUN65_RS07205	COG0584	glycerophosphoryl diester phosphodiesterase
CUN65_RS07210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUN65_RS07225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CUN65_RS07245	COG0642	Histidine kinase
CUN65_RS07245	COG2198	Histidine kinase
CUN65_RS07250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CUN65_RS07260	COG2169	Transcriptional regulator
CUN65_RS07260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUN65_RS07270	COG4615	Cyclic peptide transporter
CUN65_RS07275	COG2239	Acts as a magnesium transporter
CUN65_RS07280	COG0659	secondary active sulfate transmembrane transporter activity
CUN65_RS07285	COG0579	oxidoreductase
CUN65_RS07295	COG3182	Iron-regulated membrane protein
CUN65_RS07310	COG3082	Protein of unknown function (DUF1414)
CUN65_RS07315	COG3081	Nucleoid-associated protein
CUN65_RS07325	COG1061	Type III restriction enzyme res subunit
CUN65_RS07330	COG1187	pseudouridine synthase activity
CUN65_RS07335	COG2814	Major facilitator Superfamily
CUN65_RS07345	COG4172	Belongs to the ABC transporter superfamily
CUN65_RS07350	COG4239	(ABC) transporter, permease
CUN65_RS07355	COG4174	ABC transporter (Permease)
CUN65_RS07360	COG4166	transmembrane transport
CUN65_RS07365	COG2200	EAL domain
CUN65_RS07370	COG0791	NLP P60 protein
CUN65_RS07375	COG0671	phosphoesterase, PA-phosphatase related
CUN65_RS07380	COG0523	cobalamin synthesis protein
CUN65_RS07385	COG0246	Mannitol dehydrogenase
CUN65_RS07390	COG1312	Catalyzes the dehydration of D-mannonate
CUN65_RS07395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CUN65_RS07415	COG1105	Belongs to the carbohydrate kinase PfkB family
CUN65_RS07420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CUN65_RS07420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS07420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS07425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CUN65_RS07430	COG2855	membrane
CUN65_RS07435	COG0583	DNA-binding transcription factor activity
CUN65_RS07440	COG0833	amino acid
CUN65_RS07445	COG4771	TonB-dependent receptor
CUN65_RS07450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CUN65_RS07455	COG0477	Major facilitator Superfamily
CUN65_RS07465	COG2311	Membrane
CUN65_RS07485	COG1129	ABC transporter
CUN65_RS07505	COG2949	membrane
CUN65_RS07510	COG0295	cytidine deaminase activity
CUN65_RS07515	COG1346	cytolysis
CUN65_RS07525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUN65_RS07535	COG1538	Outer membrane efflux protein
CUN65_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS07545	COG0586	Pfam SNARE associated Golgi protein
CUN65_RS07555	COG1686	Belongs to the peptidase S11 family
CUN65_RS07565	COG0277	FAD linked oxidase domain protein
CUN65_RS07570	COG1472	Belongs to the glycosyl hydrolase 3 family
CUN65_RS07575	COG1732	Glycine betaine
CUN65_RS07580	COG1174	glycine betaine transport
CUN65_RS07585	COG1125	glycine betaine transport
CUN65_RS07590	COG1174	glycine betaine transport
CUN65_RS07600	COG0789	Transcriptional regulator
CUN65_RS07605	COG3275	phosphorelay sensor kinase activity
CUN65_RS07610	COG3279	Response regulator of the LytR AlgR family
CUN65_RS07615	COG4807	Protein conserved in bacteria
CUN65_RS07625	COG0489	protein tyrosine kinase activity
CUN65_RS07635	COG5455	response to cobalt ion
CUN65_RS07640	COG1596	polysaccharide export
CUN65_RS07645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUN65_RS07650	COG0489	protein tyrosine kinase activity
CUN65_RS07650	COG3206	protein involved in exopolysaccharide biosynthesis
CUN65_RS07655	COG0076	glutamate decarboxylase activity
CUN65_RS07660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUN65_RS07680	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CUN65_RS07685	COG0351	phosphomethylpyrimidine kinase
CUN65_RS07690	COG2188	Transcriptional regulator
CUN65_RS07695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUN65_RS07700	COG1397	ADP-ribosylglycohydrolase
CUN65_RS07705	COG2211	Major facilitator Superfamily
CUN65_RS07710	COG1830	Aldolase
CUN65_RS07715	COG1597	lipid kinase activity
CUN65_RS07730	COG0826	peptidase U32
CUN65_RS07735	COG0745	RESPONSE REGULATOR receiver
CUN65_RS07740	COG2205	protein histidine kinase activity
CUN65_RS07745	COG0477	Major facilitator Superfamily
CUN65_RS07750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS07755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS07760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS07765	COG0443	Heat shock 70 kDa protein
CUN65_RS07770	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CUN65_RS07775	COG5002	protein histidine kinase activity
CUN65_RS07775	COG3447	MASE1 domain protein
CUN65_RS07775	COG5001	Diguanylate cyclase
CUN65_RS07785	COG0717	Belongs to the dCTP deaminase family
CUN65_RS07790	COG2982	Protein involved in outer membrane biogenesis
CUN65_RS07795	COG1253	flavin adenine dinucleotide binding
CUN65_RS07810	COG3206	protein involved in exopolysaccharide biosynthesis
CUN65_RS07810	COG0489	protein tyrosine kinase activity
CUN65_RS07815	COG0463	Glycosyl transferase, family 2
CUN65_RS07820	COG1045	serine acetyltransferase
CUN65_RS07825	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS07835	COG1216	Glycosyl transferase, family 2
CUN65_RS07840	COG0110	maltose O-acetyltransferase activity
CUN65_RS07845	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CUN65_RS07850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUN65_RS07855	COG1051	belongs to the nudix hydrolase family
CUN65_RS07860	COG0297	glycogen (starch) synthase activity
CUN65_RS07870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUN65_RS07875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUN65_RS07880	COG2244	polysaccharide biosynthetic process
CUN65_RS07885	COG2327	Polysaccharide pyruvyl transferase
CUN65_RS07890	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS07930	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS07935	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS07950	COG0438	transferase activity, transferring glycosyl groups
CUN65_RS07975	COG1091	dTDP-4-dehydrorhamnose reductase activity
CUN65_RS08010	COG0140	phosphoribosyl-ATP diphosphatase activity
CUN65_RS08010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CUN65_RS08015	COG0107	imidazoleglycerol-phosphate synthase activity
CUN65_RS08020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CUN65_RS08025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CUN65_RS08030	COG0131	Imidazoleglycerol-phosphate dehydratase
CUN65_RS08030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CUN65_RS08035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CUN65_RS08045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CUN65_RS08055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUN65_RS08070	COG0531	amino acid
CUN65_RS08075	COG2925	Exonuclease
CUN65_RS08085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CUN65_RS08090	COG1289	transmembrane transporter activity
CUN65_RS08105	COG0534	Mate efflux family protein
CUN65_RS08115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUN65_RS08120	COG0477	Major facilitator Superfamily
CUN65_RS08135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS08145	COG0589	response to stress
CUN65_RS08150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUN65_RS08155	COG1376	ErfK ybiS ycfS ynhG family protein
CUN65_RS08215	COG0583	DNA-binding transcription factor activity
CUN65_RS08240	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CUN65_RS08240	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CUN65_RS08260	COG4565	transcriptional regulatory protein
CUN65_RS08265	COG3290	protein histidine kinase activity
CUN65_RS08275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CUN65_RS08280	COG1418	mRNA catabolic process
CUN65_RS08285	COG0270	DNA (cytosine-5-)-methyltransferase activity
CUN65_RS08290	COG3727	T/G mismatch-specific endonuclease activity
CUN65_RS08295	COG0697	spore germination
CUN65_RS08300	COG2354	Protein conserved in bacteria
CUN65_RS08305	COG5475	Uncharacterized small protein (DUF2158)
CUN65_RS08330	COG2197	response regulator
CUN65_RS08340	COG1987	bacterial-type flagellum assembly
CUN65_RS08380	COG1157	protein secretion by the type III secretion system
CUN65_RS08390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CUN65_RS08400	COG1677	Flagellar hook-basal body complex protein FliE
CUN65_RS08410	COG0366	Alpha amylase catalytic
CUN65_RS08420	COG1516	flagellar protein fliS
CUN65_RS08425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CUN65_RS08430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CUN65_RS08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS08455	COG0765	amino acid transport
CUN65_RS08460	COG1126	abc transporter atp-binding protein
CUN65_RS08465	COG2197	response regulator
CUN65_RS08475	COG2197	response regulator
CUN65_RS08590	COG2246	polysaccharide biosynthetic process
CUN65_RS08600	COG3772	lysozyme
CUN65_RS08620	COG0583	DNA-binding transcription factor activity
CUN65_RS08655	COG3012	SEC-C Motif Domain Protein
CUN65_RS08655	COG3318	Belongs to the UPF0149 family
CUN65_RS08660	COG0814	amino acid
CUN65_RS08670	COG1528	Iron-storage protein
CUN65_RS08700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CUN65_RS08705	COG1528	Iron-storage protein
CUN65_RS08720	COG1879	ABC-type sugar transport system periplasmic component
CUN65_RS08730	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS08740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CUN65_RS08780	COG1301	dicarboxylic acid transport
CUN65_RS08815	COG0840	transmembrane signaling receptor activity
CUN65_RS08830	COG0745	RESPONSE REGULATOR receiver
CUN65_RS08860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CUN65_RS08865	COG0018	arginyl-trna synthetase
CUN65_RS08870	COG3102	Protein conserved in bacteria
CUN65_RS08875	COG3142	Participates in the control of copper homeostasis
CUN65_RS08880	COG0500	methyltransferase
CUN65_RS08885	COG2226	methyltransferase
CUN65_RS08890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CUN65_RS08895	COG1801	Protein of unknown function DUF72
CUN65_RS08900	COG0582	viral genome integration into host DNA
CUN65_RS08970	COG4626	Terminase
CUN65_RS08970	COG1802	Transcriptional regulator
CUN65_RS08975	COG1484	DNA-dependent DNA replication
CUN65_RS08980	COG0305	Participates in initiation and elongation during chromosome replication
CUN65_RS08985	COG0484	heat shock protein binding
CUN65_RS09190	COG1335	isochorismatase
CUN65_RS09200	COG0494	nUDIX hydrolase
CUN65_RS09215	COG0632	four-way junction helicase activity
CUN65_RS09220	COG2255	four-way junction helicase activity
CUN65_RS09225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUN65_RS09235	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CUN65_RS09240	COG0739	heme binding
CUN65_RS09245	COG1560	Kdo2-lipid A biosynthetic process
CUN65_RS09255	COG1737	Transcriptional regulator
CUN65_RS09260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CUN65_RS09265	COG0129	dihydroxy-acid dehydratase activity
CUN65_RS09270	COG0800	Aldolase
CUN65_RS09320	COG2979	Protein of unknown function (DUF533)
CUN65_RS09325	COG1770	oligopeptidase
CUN65_RS09330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUN65_RS09335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUN65_RS09345	COG2372	response to copper ion
CUN65_RS09350	COG1276	copper resistance
CUN65_RS09365	COG2990	Protein conserved in bacteria
CUN65_RS09380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUN65_RS09380	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CUN65_RS09385	COG3008	intermembrane lipid transfer
CUN65_RS09390	COG2995	paraquat-inducible protein a
CUN65_RS09395	COG1956	GAF domain-containing protein
CUN65_RS09400	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CUN65_RS09410	COG0501	Belongs to the peptidase M48B family
CUN65_RS09415	COG2814	Major facilitator Superfamily
CUN65_RS09420	COG1414	Transcriptional regulator
CUN65_RS09450	COG0768	penicillin binding
CUN65_RS09455	COG2226	methyltransferase
CUN65_RS09460	COG1971	Probably functions as a manganese efflux pump
CUN65_RS09470	COG4811	Protein of unknown function (DUF986)
CUN65_RS09475	COG3716	PTS system mannose fructose sorbose family IID component
CUN65_RS09480	COG3715	PTS system
CUN65_RS09485	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS09485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS09495	COG1253	flavin adenine dinucleotide binding
CUN65_RS09500	COG2200	EAL domain
CUN65_RS09505	COG1760	l-serine dehydratase
CUN65_RS09510	COG0494	nUDIX hydrolase
CUN65_RS09525	COG0251	oxidation-reduction process
CUN65_RS09530	COG1199	ATP-dependent helicase activity
CUN65_RS09535	COG1214	PFAM Peptidase M22, glycoprotease
CUN65_RS09540	COG3065	identical protein binding
CUN65_RS09545	COG0318	PFAM AMP-dependent synthetase and ligase
CUN65_RS09550	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CUN65_RS09555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CUN65_RS09560	COG2894	cell division
CUN65_RS09565	COG0850	regulation of cytokinetic process
CUN65_RS09575	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUN65_RS09580	COG2983	Belongs to the UPF0260 family
CUN65_RS09590	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CUN65_RS09605	COG2719	SpoVR family
CUN65_RS09610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUN65_RS09615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUN65_RS09620	COG3263	regulation of cellular component size
CUN65_RS09625	COG1619	proteins homologs of microcin C7 resistance protein MccF
CUN65_RS09630	COG0741	lytic transglycosylase activity
CUN65_RS09640	COG4774	siderophore transport
CUN65_RS09655	COG4977	sequence-specific DNA binding
CUN65_RS09775	COG0515	serine threonine protein kinase
CUN65_RS09820	COG1397	ADP-ribosylglycohydrolase
CUN65_RS09830	COG1397	ADP-ribosylglycohydrolase
CUN65_RS09935	COG0012	GTP binding
CUN65_RS09980	COG0012	GTP binding
CUN65_RS09985	COG0193	aminoacyl-tRNA hydrolase activity
CUN65_RS10000	COG0659	secondary active sulfate transmembrane transporter activity
CUN65_RS10015	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CUN65_RS10025	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CUN65_RS10035	COG2890	protein-(glutamine-N5) methyltransferase activity
CUN65_RS10050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CUN65_RS10055	COG0387	Pfam Sodium calcium exchanger
CUN65_RS10060	COG4572	Cation transport regulator
CUN65_RS10065	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CUN65_RS10075	COG0840	transmembrane signaling receptor activity
CUN65_RS10080	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CUN65_RS10085	COG3707	response regulator
CUN65_RS10090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUN65_RS10100	COG1116	anion transmembrane transporter activity
CUN65_RS10105	COG2146	nitrite reductase [NAD(P)H] activity
CUN65_RS10105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUN65_RS10110	COG0243	molybdopterin cofactor binding
CUN65_RS10115	COG4932	domain protein
CUN65_RS10120	COG2197	response regulator
CUN65_RS10125	COG3850	Histidine kinase
CUN65_RS10130	COG2223	nitrite transmembrane transporter activity
CUN65_RS10135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CUN65_RS10140	COG1140	nitrate reductase beta subunit
CUN65_RS10145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CUN65_RS10150	COG2181	nitrate reductase activity
CUN65_RS10175	COG0788	formyltetrahydrofolate deformylase activity
CUN65_RS10180	COG3012	SEC-C Motif Domain Protein
CUN65_RS10185	COG1752	Esterase of the alpha-beta hydrolase superfamily
CUN65_RS10190	COG0745	RESPONSE REGULATOR receiver
CUN65_RS10195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUN65_RS10205	COG1435	thymidine kinase activity
CUN65_RS10210	COG1454	alcohol dehydrogenase
CUN65_RS10210	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS10215	COG2095	MarC family integral membrane protein
CUN65_RS10240	COG0444	Belongs to the ABC transporter superfamily
CUN65_RS10245	COG4608	Belongs to the ABC transporter superfamily
CUN65_RS10250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUN65_RS10255	COG3099	Belongs to the UPF0263 family
CUN65_RS10270	COG1280	lysine exporter protein (LysE YggA)
CUN65_RS10275	COG4974	Belongs to the 'phage' integrase family
CUN65_RS10345	COG4695	Portal protein
CUN65_RS10435	COG5301	cellulose 1,4-beta-cellobiosidase activity
CUN65_RS10435	COG5301	cellulose 1,4-beta-cellobiosidase activity
CUN65_RS10490	COG2350	Protein conserved in bacteria
CUN65_RS10510	COG2917	probably involved in intracellular septation
CUN65_RS10520	COG0727	PFAM Uncharacterised protein family (UPF0153)
CUN65_RS10525	COG3047	cAMP biosynthetic process
CUN65_RS10530	COG0425	Belongs to the sulfur carrier protein TusA family
CUN65_RS10535	COG2391	methyltransferase activity
CUN65_RS10540	COG0159	tryptophan synthase activity
CUN65_RS10545	COG0133	tryptophan synthase activity
CUN65_RS10555	COG0512	Glutamine amidotransferase of anthranilate synthase
CUN65_RS10555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUN65_RS10570	COG0613	PHP domain protein
CUN65_RS10575	COG0009	L-threonylcarbamoyladenylate synthase
CUN65_RS10585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CUN65_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS10595	COG0616	signal peptide processing
CUN65_RS10620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CUN65_RS10630	COG0671	phosphoesterase, PA-phosphatase related
CUN65_RS10635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CUN65_RS10640	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CUN65_RS10645	COG0284	orotidine-5'-phosphate decarboxylase activity
CUN65_RS10650	COG0023	Translation Initiation Factor
CUN65_RS10660	COG1349	DNA-binding transcription factor activity
CUN65_RS10670	COG1024	Enoyl-CoA hydratase
CUN65_RS10675	COG5001	Diguanylate cyclase
CUN65_RS10680	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CUN65_RS10685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUN65_RS10685	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUN65_RS10690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CUN65_RS10695	COG3706	GGDEF domain
CUN65_RS10700	COG2207	Transcriptional regulator
CUN65_RS10700	COG3708	Transcriptional regulator
CUN65_RS10705	COG0251	oxidation-reduction process
CUN65_RS10715	COG4172	Belongs to the ABC transporter superfamily
CUN65_RS10725	COG4171	peptide transport system, permease
CUN65_RS10740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CUN65_RS10745	COG1842	Phage shock protein A
CUN65_RS10755	COG1983	PspC domain protein
CUN65_RS10765	COG0366	Alpha amylase catalytic
CUN65_RS10770	COG1653	transport
CUN65_RS10775	COG1175	transmembrane transport
CUN65_RS10780	COG0395	ABC-type sugar transport system, permease component
CUN65_RS10785	COG1063	alcohol dehydrogenase
CUN65_RS10790	COG1082	Xylose isomerase domain protein TIM barrel
CUN65_RS10800	COG1554	hydrolase, family 65, central catalytic
CUN65_RS10805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUN65_RS10810	COG3842	ATPase activity
CUN65_RS10820	COG1609	Transcriptional regulator
CUN65_RS10825	COG3106	COG3106 Predicted ATPase
CUN65_RS10830	COG3768	UPF0283 membrane protein
CUN65_RS10840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CUN65_RS10845	COG4948	Mandelate Racemase Muconate Lactonizing
CUN65_RS10850	COG2866	Carboxypeptidase
CUN65_RS10855	COG4166	transmembrane transport
CUN65_RS10890	COG0840	transmembrane signaling receptor activity
CUN65_RS10905	COG0513	Belongs to the DEAD box helicase family
CUN65_RS10935	COG1902	pentaerythritol trinitrate reductase activity
CUN65_RS10950	COG0582	viral genome integration into host DNA
CUN65_RS10965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CUN65_RS10970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CUN65_RS10970	COG1013	pyruvate-flavodoxin oxidoreductase activity
CUN65_RS10970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUN65_RS10970	COG0674	pyruvate-flavodoxin oxidoreductase activity
CUN65_RS10975	COG3042	response to heat
CUN65_RS10980	COG3187	Heat shock protein
CUN65_RS10990	COG1294	oxidase, subunit
CUN65_RS10995	COG1271	oxidase subunit
CUN65_RS11005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUN65_RS11010	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS11020	COG3615	Tellurite resistance protein tehB
CUN65_RS11025	COG3615	Tellurite resistance protein tehB
CUN65_RS11055	COG0747	negative chemotaxis
CUN65_RS11065	COG3238	Protein conserved in bacteria
CUN65_RS11070	COG1247	-acetyltransferase
CUN65_RS11080	COG2130	NADP-dependent
CUN65_RS11085	COG1802	Transcriptional regulator
CUN65_RS11090	COG4772	TonB-dependent receptor
CUN65_RS11120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS11125	COG1473	amidohydrolase
CUN65_RS11130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS11135	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CUN65_RS11150	COG1126	abc transporter atp-binding protein
CUN65_RS11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS11160	COG0625	glutathione transferase activity
CUN65_RS11165	COG1942	4-Oxalocrotonate Tautomerase
CUN65_RS11170	COG1560	Kdo2-lipid A biosynthetic process
CUN65_RS11180	COG0640	Transcriptional regulator
CUN65_RS11185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CUN65_RS11200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUN65_RS11205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CUN65_RS11210	COG2181	nitrate reductase activity
CUN65_RS11215	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CUN65_RS11220	COG1140	nitrate reductase beta subunit
CUN65_RS11225	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CUN65_RS11230	COG2223	nitrite transmembrane transporter activity
CUN65_RS11255	COG0243	molybdopterin cofactor binding
CUN65_RS11255	COG3383	formate dehydrogenase (NAD+) activity
CUN65_RS11260	COG0243	molybdopterin cofactor binding
CUN65_RS11260	COG3383	formate dehydrogenase (NAD+) activity
CUN65_RS11265	COG0437	4 iron, 4 sulfur cluster binding
CUN65_RS11270	COG2864	formate dehydrogenase
CUN65_RS11280	COG2814	Major facilitator Superfamily
CUN65_RS11285	COG1252	NADH dehydrogenase
CUN65_RS11295	COG1064	alcohol dehydrogenase
CUN65_RS11305	COG0281	malic enzyme
CUN65_RS11335	COG1764	response to oxidative stress
CUN65_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS11350	COG4608	Belongs to the ABC transporter superfamily
CUN65_RS11355	COG0444	Belongs to the ABC transporter superfamily
CUN65_RS11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUN65_RS11365	COG0601	transmembrane transport
CUN65_RS11370	COG0747	negative chemotaxis
CUN65_RS11375	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CUN65_RS11390	COG2200	EAL domain
CUN65_RS11420	COG0840	transmembrane signaling receptor activity
CUN65_RS11435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUN65_RS11440	COG1649	PFAM Uncharacterised BCR, COG1649
CUN65_RS11445	COG4628	conserved protein (DUF2132)
CUN65_RS11450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CUN65_RS11455	COG0583	DNA-binding transcription factor activity
CUN65_RS11465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUN65_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS11480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CUN65_RS11515	COG2814	Major facilitator Superfamily
CUN65_RS11540	COG1349	DNA-binding transcription factor activity
CUN65_RS11545	COG0494	nUDIX hydrolase
CUN65_RS11570	COG0596	Alpha beta hydrolase
CUN65_RS11590	COG3781	membrane
CUN65_RS11595	COG0246	Mannitol dehydrogenase
CUN65_RS11605	COG3706	GGDEF domain
CUN65_RS11615	COG2066	Belongs to the glutaminase family
CUN65_RS11625	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS11630	COG0583	DNA-binding transcription factor activity
CUN65_RS11645	COG2814	Major facilitator Superfamily
CUN65_RS11655	COG1846	Transcriptional regulator
CUN65_RS11670	COG0697	spore germination
CUN65_RS11675	COG2814	Major facilitator Superfamily
CUN65_RS11680	COG3443	Belongs to the bacterial solute-binding protein 9 family
CUN65_RS11690	COG1122	ATPase activity
CUN65_RS11710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CUN65_RS11735	COG0826	peptidase U32
CUN65_RS11740	COG1396	sequence-specific DNA binding
CUN65_RS11745	COG3135	benzoate transporter
CUN65_RS11765	COG0747	negative chemotaxis
CUN65_RS11770	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUN65_RS11775	COG0500	methyltransferase
CUN65_RS11780	COG1275	C4-dicarboxylate transporter malic acid transport protein
CUN65_RS11785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUN65_RS11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS11795	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CUN65_RS11805	COG0436	Aminotransferase
CUN65_RS11815	COG2272	Belongs to the type-B carboxylesterase lipase family
CUN65_RS11820	COG5383	Protein conserved in bacteria
CUN65_RS11825	COG0583	DNA-binding transcription factor activity
CUN65_RS11830	COG0840	transmembrane signaling receptor activity
CUN65_RS11895	COG2274	protein secretion by the type I secretion system
CUN65_RS11910	COG1349	DNA-binding transcription factor activity
CUN65_RS11915	COG0673	inositol 2-dehydrogenase activity
CUN65_RS11920	COG3038	cytochrome b561
CUN65_RS11925	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS11930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CUN65_RS11945	COG1538	Outer membrane efflux protein
CUN65_RS11950	COG1643	Atp-dependent helicase
CUN65_RS11960	COG0564	pseudouridine synthase activity
CUN65_RS11965	COG3122	Protein conserved in bacteria
CUN65_RS12010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CUN65_RS12025	COG0300	oxidoreductase activity
CUN65_RS12045	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CUN65_RS12055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUN65_RS12060	COG3327	negative regulation of DNA-templated transcription, initiation
CUN65_RS12065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CUN65_RS12070	COG0183	Belongs to the thiolase family
CUN65_RS12075	COG2050	protein possibly involved in aromatic compounds catabolism
CUN65_RS12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUN65_RS12085	COG1024	Enoyl-CoA hydratase
CUN65_RS12090	COG1024	Enoyl-CoA hydratase
CUN65_RS12095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUN65_RS12100	COG2151	metal-sulfur cluster biosynthetic enzyme
CUN65_RS12105	COG3396	Phenylacetate-CoA oxygenase
CUN65_RS12110	COG3460	Phenylacetate-CoA oxygenase
CUN65_RS12115	COG3396	Phenylacetate-CoA oxygenase
CUN65_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS12120	COG2030	dehydratase
CUN65_RS12125	COG3733	amine oxidase
CUN65_RS12130	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CUN65_RS12135	COG4251	negative regulation of phosphorylation
CUN65_RS12135	COG5001	Diguanylate cyclase
CUN65_RS12135	COG2203	Gaf domain
CUN65_RS12135	COG3706	GGDEF domain
CUN65_RS12140	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS12145	COG2207	Transcriptional regulator
CUN65_RS12150	COG3784	Protein of unknown function (DUF1318)
CUN65_RS12160	COG2911	Protein conserved in bacteria
CUN65_RS12165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUN65_RS12190	COG4993	Dehydrogenase
CUN65_RS12200	COG0814	amino acid
CUN65_RS12210	COG2135	peptidase activity
CUN65_RS12215	COG1683	Conserved Protein
CUN65_RS12235	COG4221	oxidoreductase activity
CUN65_RS12240	COG1802	Transcriptional regulator
CUN65_RS12245	COG0589	response to stress
CUN65_RS12255	COG0246	Mannitol dehydrogenase
CUN65_RS12260	COG0477	Major facilitator Superfamily
CUN65_RS12265	COG1063	alcohol dehydrogenase
CUN65_RS12270	COG4948	Mandelate Racemase Muconate Lactonizing
CUN65_RS12285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS12305	COG0243	molybdopterin cofactor binding
CUN65_RS12340	COG0243	molybdopterin cofactor binding
CUN65_RS12345	COG0437	4 iron, 4 sulfur cluster binding
CUN65_RS12350	COG3302	dmso reductase anchor subunit
CUN65_RS12355	COG3381	protein complex oligomerization
CUN65_RS12360	COG3141	response to X-ray
CUN65_RS12410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CUN65_RS12415	COG1940	carbohydrate kinase activity
CUN65_RS12420	COG0583	DNA-binding transcription factor activity
CUN65_RS12425	COG2814	Major facilitator Superfamily
CUN65_RS12430	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CUN65_RS12445	COG3591	Belongs to the peptidase S1B family
CUN65_RS12450	COG2076	Multidrug Resistance protein
CUN65_RS12455	COG2076	Multidrug Resistance protein
CUN65_RS12460	COG0628	permease
CUN65_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS12475	COG1403	HNH endonuclease
CUN65_RS12480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUN65_RS12520	COG4993	Dehydrogenase
CUN65_RS12535	COG0667	Aldo Keto reductase
CUN65_RS12545	COG2840	Smr protein MutS2
CUN65_RS12550	COG0583	DNA-binding transcription factor activity
CUN65_RS12560	COG1473	amidohydrolase
CUN65_RS12565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CUN65_RS12570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUN65_RS12580	COG0589	response to stress
CUN65_RS12585	COG0668	transmembrane transport
CUN65_RS12590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CUN65_RS12595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CUN65_RS12605	COG0531	amino acid
CUN65_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS12615	COG3136	membrane protein required for alginate biosynthesis
CUN65_RS12620	COG0745	RESPONSE REGULATOR receiver
CUN65_RS12630	COG2205	protein histidine kinase activity
CUN65_RS12645	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CUN65_RS12645	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CUN65_RS12655	COG5339	Protein conserved in bacteria
CUN65_RS12660	COG1609	Transcriptional regulator
CUN65_RS12665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS12665	COG1263	PTS System
CUN65_RS12670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUN65_RS12675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CUN65_RS12680	COG0673	inositol 2-dehydrogenase activity
CUN65_RS12730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUN65_RS12735	COG3104	oligopeptide transport
CUN65_RS12740	COG0625	glutathione transferase activity
CUN65_RS12745	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CUN65_RS12750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CUN65_RS12755	COG0259	pyridoxamine-phosphate oxidase activity
CUN65_RS12760	COG3895	Periplasmic Protein
CUN65_RS12765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CUN65_RS12775	COG3706	GGDEF domain
CUN65_RS12790	COG1566	PFAM secretion protein HlyD family protein
CUN65_RS12795	COG1289	transmembrane transporter activity
CUN65_RS12800	COG2032	superoxide dismutase activity
CUN65_RS12805	COG4989	oxidoreductase activity
CUN65_RS12810	COG3313	Fe-S protein
CUN65_RS12815	COG2194	sulfuric ester hydrolase activity
CUN65_RS12820	COG1309	transcriptional regulator
CUN65_RS12825	COG1902	pentaerythritol trinitrate reductase activity
CUN65_RS12830	COG0346	lactoylglutathione lyase activity
CUN65_RS12840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CUN65_RS12845	COG0791	NLP P60 protein
CUN65_RS12855	COG2814	Major facilitator Superfamily
CUN65_RS12870	COG0583	DNA-binding transcription factor activity
CUN65_RS12875	COG2814	Major facilitator Superfamily
CUN65_RS12880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CUN65_RS12885	COG0307	riboflavin synthase, alpha
CUN65_RS12890	COG0534	Mate efflux family protein
CUN65_RS12905	COG0071	Belongs to the small heat shock protein (HSP20) family
CUN65_RS12955	COG4529	Protein conserved in bacteria
CUN65_RS12965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUN65_RS12980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS12990	COG0765	amino acid transport
CUN65_RS12995	COG0765	amino acid transport
CUN65_RS13005	COG1464	Belongs to the NlpA lipoprotein family
CUN65_RS13010	COG2011	ABC-type metal ion transport system permease component
CUN65_RS13025	COG0626	cystathionine gamma-synthase activity
CUN65_RS13040	COG1376	ErfK ybiS ycfS ynhG family protein
CUN65_RS13045	COG2166	iron-sulfur cluster assembly
CUN65_RS13050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUN65_RS13055	COG0719	Fe-S assembly protein
CUN65_RS13060	COG0396	ATPase activity
CUN65_RS13065	COG0719	Fe-S assembly protein
CUN65_RS13070	COG0316	Belongs to the HesB IscA family
CUN65_RS13090	COG0789	Transcriptional regulator
CUN65_RS13095	COG2200	EAL domain
CUN65_RS13115	COG3383	formate dehydrogenase (NAD+) activity
CUN65_RS13140	COG3121	Chaperone
CUN65_RS13145	COG3539	Fimbrial protein
CUN65_RS13155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUN65_RS13165	COG2050	protein possibly involved in aromatic compounds catabolism
CUN65_RS13170	COG0247	lactate metabolic process
CUN65_RS13170	COG0277	FAD linked oxidase domain protein
CUN65_RS13175	COG0628	permease
CUN65_RS13185	COG1472	Belongs to the glycosyl hydrolase 3 family
CUN65_RS13190	COG2211	Major facilitator Superfamily
CUN65_RS13195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUN65_RS13195	COG0574	Belongs to the PEP-utilizing enzyme family
CUN65_RS13200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CUN65_RS13205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUN65_RS13210	COG4256	Hemin uptake protein
CUN65_RS13220	COG3720	iron ion transport
CUN65_RS13225	COG4558	Periplasmic binding protein
CUN65_RS13230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS13240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CUN65_RS13250	COG0791	NLP P60 protein
CUN65_RS13260	COG0386	Belongs to the glutathione peroxidase family
CUN65_RS13265	COG2135	peptidase activity
CUN65_RS13345	COG1178	ABC-type Fe3 transport system permease component
CUN65_RS13345	COG1674	ftsk spoiiie
CUN65_RS13405	COG1349	DNA-binding transcription factor activity
CUN65_RS13420	COG1846	Transcriptional regulator
CUN65_RS13470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUN65_RS13490	COG0582	viral genome integration into host DNA
CUN65_RS13500	COG0776	regulation of translation
CUN65_RS13505	COG0072	phenylalanine-tRNA ligase activity
CUN65_RS13505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUN65_RS13510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CUN65_RS13555	COG3137	Salt-induced outer membrane protein
CUN65_RS13560	COG1105	Belongs to the carbohydrate kinase PfkB family
CUN65_RS13570	COG3001	Fructosamine kinase
CUN65_RS13580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUN65_RS13585	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS13590	COG1988	membrane-bound metal-dependent
CUN65_RS13595	COG1823	symporter activity
CUN65_RS13605	COG0753	catalase activity
CUN65_RS13610	COG3394	polysaccharide catabolic process
CUN65_RS13615	COG1486	melibiose metabolic process
CUN65_RS13620	COG1917	Cupin 2, conserved barrel domain protein
CUN65_RS13620	COG2169	Transcriptional regulator
CUN65_RS13625	COG1447	Phosphotransferase system cellobiose-specific component IIA
CUN65_RS13630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS13635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS13640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUN65_RS13650	COG0322	excinuclease ABC activity
CUN65_RS13660	COG3678	ATP-independent chaperone mediated protein folding
CUN65_RS13670	COG3724	N-succinylarginine dihydrolase activity
CUN65_RS13675	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS13680	COG3138	arginine N-succinyltransferase
CUN65_RS13690	COG0708	Exodeoxyribonuclease III
CUN65_RS13700	COG4134	Bacterial extracellular solute-binding protein
CUN65_RS13705	COG4135	transport system, permease component
CUN65_RS13710	COG4136	ATPase activity
CUN65_RS13715	COG2897	thiosulfate sulfurtransferase activity
CUN65_RS13720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUN65_RS13725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUN65_RS13730	COG0494	nUDIX hydrolase
CUN65_RS13745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CUN65_RS13750	COG0709	Synthesizes selenophosphate from selenide and ATP
CUN65_RS13755	COG0778	Nitroreductase
CUN65_RS13765	COG0616	signal peptide processing
CUN65_RS13770	COG0252	asparaginase activity
CUN65_RS13775	COG1335	isochorismatase
CUN65_RS13785	COG3139	Protein of unknown function (DUF1315)
CUN65_RS13805	COG3713	MltA-interacting MipA family protein
CUN65_RS13810	COG2766	serine protein kinase
CUN65_RS13815	COG2718	Belongs to the UPF0229 family
CUN65_RS13935	COG0740	serine-type endopeptidase activity
CUN65_RS13940	COG4695	Portal protein
CUN65_RS13945	COG1802	Transcriptional regulator
CUN65_RS13945	COG4626	Terminase
CUN65_RS13990	COG3179	chitinase
CUN65_RS14010	COG1403	HNH endonuclease
CUN65_RS14040	COG1846	Transcriptional regulator
CUN65_RS14120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUN65_RS14125	COG2211	Major facilitator Superfamily
CUN65_RS14135	COG2707	UPF0756 membrane protein
CUN65_RS14140	COG2207	Transcriptional regulator
CUN65_RS14145	COG2807	transmembrane transport
CUN65_RS14150	COG0504	CTP synthase activity
CUN65_RS14155	COG3189	MarR family transcriptional regulator
CUN65_RS14165	COG3042	response to heat
CUN65_RS14175	COG2199	diguanylate cyclase activity
CUN65_RS14175	COG2203	Gaf domain
CUN65_RS14190	COG2261	transglycosylase associated protein
CUN65_RS14205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CUN65_RS14215	COG0538	isocitrate dehydrogenase activity
CUN65_RS14220	COG1187	pseudouridine synthase activity
CUN65_RS14235	COG2915	High frequency lysogenization protein hflD homolog
CUN65_RS14240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUN65_RS14255	COG2205	protein histidine kinase activity
CUN65_RS14260	COG2850	peptidyl-arginine hydroxylation
CUN65_RS14300	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUN65_RS14305	COG1136	(ABC) transporter
CUN65_RS14310	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUN65_RS14315	COG4763	Acyl-transferase
CUN65_RS14320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CUN65_RS14325	COG1376	ErfK ybiS ycfS ynhG family protein
CUN65_RS14325	COG1388	LysM domain
CUN65_RS14335	COG1309	transcriptional regulator
CUN65_RS14340	COG3134	Outer membrane lipoprotein
CUN65_RS14345	COG1252	NADH dehydrogenase
CUN65_RS14350	COG3150	esterase
CUN65_RS14365	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CUN65_RS14370	COG5633	Lipoprotein
CUN65_RS14375	COG0537	adenosine 5'-monophosphoramidase activity
CUN65_RS14380	COG4773	Receptor
CUN65_RS14390	COG0084	hydrolase, TatD family'
CUN65_RS14395	COG0470	DNA polymerase III
CUN65_RS14405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUN65_RS14410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUN65_RS14415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS14420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUN65_RS14435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUN65_RS14440	COG0416	fatty acid biosynthetic process
CUN65_RS14445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CUN65_RS14455	COG0424	maF-like protein
CUN65_RS14460	COG0564	pseudouridine synthase activity
CUN65_RS14470	COG1530	ribonuclease E activity
CUN65_RS14475	COG0583	DNA-binding transcription factor activity
CUN65_RS14480	COG2814	Major facilitator Superfamily
CUN65_RS14490	COG1256	bacterial-type flagellum assembly
CUN65_RS14510	COG4786	Flagellar basal body rod
CUN65_RS14520	COG1749	Flagellar hook protein flgE
CUN65_RS14530	COG1558	bacterial-type flagellum-dependent cell motility
CUN65_RS14565	COG3132	Protein of unknown function, DUF480
CUN65_RS14570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS14575	COG0477	Major facilitator Superfamily
CUN65_RS14585	COG0418	dihydroorotase activity
CUN65_RS14610	COG3038	cytochrome b561
CUN65_RS14615	COG2353	YceI-like domain
CUN65_RS14620	COG1054	Belongs to the UPF0176 family
CUN65_RS14625	COG1560	Kdo2-lipid A biosynthetic process
CUN65_RS14640	COG5645	(Lipo)protein
CUN65_RS14645	COG2943	transferase activity, transferring hexosyl groups
CUN65_RS14665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CUN65_RS14715	COG3381	protein complex oligomerization
CUN65_RS14720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CUN65_RS14725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUN65_RS14735	COG0583	DNA-binding transcription factor activity
CUN65_RS14745	COG1335	isochorismatase
CUN65_RS14760	COG1702	phosphate starvation-inducible protein PhoH
CUN65_RS14770	COG2822	iron ion transport
CUN65_RS14785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CUN65_RS14795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUN65_RS14800	COG0506	proline dehydrogenase activity
CUN65_RS14800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CUN65_RS14800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CUN65_RS14810	COG1309	transcriptional regulator
CUN65_RS14815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS14820	COG1335	isochorismatase
CUN65_RS14825	COG0251	oxidation-reduction process
CUN65_RS14830	COG2267	carboxylic ester hydrolase activity
CUN65_RS14835	COG0778	Nitroreductase
CUN65_RS14840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUN65_RS14845	COG2233	PERMEase
CUN65_RS14855	COG3729	General stress protein
CUN65_RS14880	COG2239	Acts as a magnesium transporter
CUN65_RS14895	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CUN65_RS14895	COG3264	Mechanosensitive ion channel
CUN65_RS14905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS14910	COG1120	ATPase activity
CUN65_RS14930	COG0670	Belongs to the BI1 family
CUN65_RS14940	COG1254	Belongs to the acylphosphatase family
CUN65_RS14945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUN65_RS14955	COG1832	CoA-binding protein
CUN65_RS14960	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CUN65_RS14965	COG1803	Methylglyoxal synthase
CUN65_RS14970	COG0210	DNA helicase
CUN65_RS14975	COG3304	Inner membrane component domain
CUN65_RS14980	COG1289	transmembrane transporter activity
CUN65_RS14985	COG3070	regulator of competence-specific genes
CUN65_RS14990	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CUN65_RS15000	COG3120	sequence-specific DNA binding
CUN65_RS15005	COG1067	ATP-dependent peptidase activity
CUN65_RS15015	COG3130	regulation of translation
CUN65_RS15025	COG3009	Protein conserved in bacteria
CUN65_RS15030	COG3008	intermembrane lipid transfer
CUN65_RS15030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CUN65_RS15035	COG2995	paraquat-inducible protein a
CUN65_RS15040	COG0488	(ABC) transporter
CUN65_RS15045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUN65_RS15045	COG0116	Belongs to the methyltransferase superfamily
CUN65_RS15050	COG3217	Mosc domain protein beta barrel domain protein
CUN65_RS15050	COG0633	Ferredoxin
CUN65_RS15060	COG0167	dihydroorotate dehydrogenase activity
CUN65_RS15065	COG0431	NADPH-dependent FMN reductase
CUN65_RS15070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUN65_RS15075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUN65_RS15080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUN65_RS15090	COG0308	aminopeptidase N
CUN65_RS15095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CUN65_RS15100	COG0017	Asparaginyl-tRNA synthetase
CUN65_RS15110	COG1448	Aminotransferase
CUN65_RS15115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUN65_RS15120	COG3108	Peptidase M15
CUN65_RS15125	COG2989	Protein conserved in bacteria
CUN65_RS15130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CUN65_RS15135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CUN65_RS15145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CUN65_RS15150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CUN65_RS15155	COG3173	Aminoglycoside phosphotransferase
CUN65_RS15160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CUN65_RS15165	COG2835	tetraacyldisaccharide 4'-kinase activity
CUN65_RS15170	COG3214	Protein conserved in bacteria
CUN65_RS15180	COG1132	(ABC) transporter
CUN65_RS15185	COG2333	competence protein COMEC
CUN65_RS15185	COG0658	competence protein
CUN65_RS15190	COG0776	regulation of translation
CUN65_RS15195	COG0539	negative regulation of cytoplasmic translation
CUN65_RS15200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CUN65_RS15205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CUN65_RS15210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CUN65_RS15215	COG2323	membrane
CUN65_RS15220	COG1944	ATP diphosphatase activity
CUN65_RS15225	COG2116	formate transmembrane transporter activity
CUN65_RS15230	COG1882	Formate acetyltransferase
CUN65_RS15235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUN65_RS15245	COG0477	Major facilitator Superfamily
CUN65_RS15255	COG3302	dmso reductase anchor subunit
CUN65_RS15260	COG0437	4 iron, 4 sulfur cluster binding
CUN65_RS15265	COG0243	molybdopterin cofactor binding
CUN65_RS15270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CUN65_RS15275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUN65_RS15280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CUN65_RS15285	COG1178	ABC-type Fe3 transport system permease component
CUN65_RS15285	COG1674	ftsk spoiiie
CUN65_RS15300	COG0492	ferredoxin-NADP+ reductase activity
CUN65_RS15305	COG4988	ABC transporter
CUN65_RS15310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CUN65_RS15315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CUN65_RS15320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CUN65_RS15330	COG0542	response to heat
CUN65_RS15335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CUN65_RS15340	COG1278	Cold shock
CUN65_RS15350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS15355	COG2990	Protein conserved in bacteria
CUN65_RS15360	COG3593	DNA synthesis involved in DNA repair
CUN65_RS15370	COG2431	L-lysine efflux transmembrane transporter activity
CUN65_RS15375	COG1151	hydroxylamine reductase activity
CUN65_RS15380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUN65_RS15385	COG0028	Belongs to the TPP enzyme family
CUN65_RS15390	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CUN65_RS15395	COG0702	epimerase
CUN65_RS15400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUN65_RS15405	COG3397	chitin binding
CUN65_RS15420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CUN65_RS15440	COG2165	general secretion pathway protein
CUN65_RS15450	COG2165	general secretion pathway protein
CUN65_RS15460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUN65_RS15465	COG1450	Type ii and iii secretion system protein
CUN65_RS15470	COG3031	protein transport across the cell outer membrane
CUN65_RS15490	COG3023	N-Acetylmuramoyl-L-alanine amidase
CUN65_RS15495	COG0393	Putative heavy-metal-binding
CUN65_RS15505	COG1126	abc transporter atp-binding protein
CUN65_RS15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS15515	COG4215	(ABC) transporter
CUN65_RS15520	COG4160	amino acid transport
CUN65_RS15530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS15535	COG5002	protein histidine kinase activity
CUN65_RS15540	COG0745	RESPONSE REGULATOR receiver
CUN65_RS15545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUN65_RS15555	COG1177	transmembrane transport
CUN65_RS15560	COG1176	ABC-type spermidine putrescine transport system, permease component I
CUN65_RS15565	COG3842	ATPase activity
CUN65_RS15570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CUN65_RS15590	COG0778	Nitroreductase
CUN65_RS15610	COG0640	Transcriptional regulator
CUN65_RS15615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CUN65_RS15620	COG1393	Belongs to the ArsC family
CUN65_RS15625	COG3226	Transcriptional regulator
CUN65_RS15630	COG0738	Major facilitator superfamily
CUN65_RS15635	COG0561	phosphatase activity
CUN65_RS15640	COG2814	Major facilitator Superfamily
CUN65_RS15650	COG0671	phosphoesterase, PA-phosphatase related
CUN65_RS15655	COG1349	DNA-binding transcription factor activity
CUN65_RS15660	COG1686	Belongs to the peptidase S11 family
CUN65_RS15665	COG0625	glutathione transferase activity
CUN65_RS15670	COG2133	pyrroloquinoline quinone binding
CUN65_RS15705	COG1446	asparaginase
CUN65_RS15710	COG0303	'Molybdopterin
CUN65_RS15720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CUN65_RS15725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUN65_RS15730	COG1882	Formate acetyltransferase
CUN65_RS15735	COG0561	phosphatase activity
CUN65_RS15745	COG1609	Transcriptional regulator
CUN65_RS15750	COG2271	Major facilitator Superfamily
CUN65_RS15760	COG0488	(ABC) transporter
CUN65_RS15765	COG1376	ErfK ybiS ycfS ynhG family protein
CUN65_RS15770	COG2188	Transcriptional regulator
CUN65_RS15775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS15780	COG2723	6-phospho-beta-galactosidase activity
CUN65_RS15785	COG0667	Aldo Keto reductase
CUN65_RS15795	COG2814	Major facilitator Superfamily
CUN65_RS15800	COG1566	PFAM secretion protein HlyD family protein
CUN65_RS15805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CUN65_RS15810	COG1321	iron dependent repressor
CUN65_RS15820	COG2194	sulfuric ester hydrolase activity
CUN65_RS15825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CUN65_RS15835	COG0783	Belongs to the Dps family
CUN65_RS15840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUN65_RS15845	COG0765	amino acid transport
CUN65_RS15850	COG1126	abc transporter atp-binding protein
CUN65_RS15855	COG0668	transmembrane transport
CUN65_RS15860	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CUN65_RS15875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUN65_RS15885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUN65_RS15890	COG3539	Fimbrial protein
CUN65_RS15895	COG3121	Chaperone
CUN65_RS15915	COG1199	ATP-dependent helicase activity
CUN65_RS15920	COG0513	Belongs to the DEAD box helicase family
CUN65_RS15925	COG1309	transcriptional regulator
CUN65_RS15930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS15935	COG1131	(ABC) transporter
CUN65_RS15940	COG0842	Transport permease protein
CUN65_RS15945	COG0842	Transport permease protein
CUN65_RS15955	COG3568	Endonuclease Exonuclease Phosphatase
CUN65_RS15960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUN65_RS15965	COG0392	lysyltransferase activity
CUN65_RS15970	COG0670	Belongs to the BI1 family
CUN65_RS15975	COG0314	molybdopterin synthase activity
CUN65_RS15980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CUN65_RS15985	COG0315	cyclic pyranopterin monophosphate synthase activity
CUN65_RS15990	COG0521	Mo-molybdopterin cofactor biosynthetic process
CUN65_RS16030	COG0156	8-amino-7-oxononanoate synthase activity
CUN65_RS16035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CUN65_RS16040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CUN65_RS16045	COG1881	PFAM PEBP family protein
CUN65_RS16050	COG2986	histidine ammonia-lyase
CUN65_RS16055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CUN65_RS16065	COG0010	Belongs to the arginase family
CUN65_RS16075	COG4677	pectinesterase activity
CUN65_RS16080	COG2706	6-phosphogluconolactonase activity
CUN65_RS16085	COG0561	phosphatase activity
CUN65_RS16095	COG4149	molybdate abc transporter
CUN65_RS16100	COG0725	ABC transporter, periplasmic molybdate-binding protein
CUN65_RS16110	COG3585	molybdate ion transport
CUN65_RS16110	COG2005	Transcriptional regulator
CUN65_RS16115	COG1119	ATPase activity
CUN65_RS16120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUN65_RS16125	COG1085	galactose-1-phosphate uridylyltransferase
CUN65_RS16130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CUN65_RS16135	COG2017	converts alpha-aldose to the beta-anomer
CUN65_RS16145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUN65_RS16155	COG1230	cation diffusion facilitator family transporter
CUN65_RS16160	COG3201	nicotinamide mononucleotide transporter
CUN65_RS16165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CUN65_RS16195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CUN65_RS16200	COG2885	chlorophyll binding
CUN65_RS16205	COG0823	Involved in the tonB-independent uptake of proteins
CUN65_RS16210	COG3064	Membrane
CUN65_RS16215	COG0848	biopolymer transport protein
CUN65_RS16220	COG0811	peptide transport
CUN65_RS16225	COG0824	Thioesterase
CUN65_RS16230	COG3790	cyd operon protein YbgE
CUN65_RS16235	COG4890	Cyd operon protein YbgT
CUN65_RS16240	COG1294	oxidase, subunit
CUN65_RS16245	COG1271	oxidase subunit
CUN65_RS16250	COG0383	alpha-mannosidase activity
CUN65_RS16255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS16255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS16255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS16260	COG2188	Transcriptional regulator
CUN65_RS16265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CUN65_RS16270	COG0045	succinate-CoA ligase (ADP-forming) activity
CUN65_RS16275	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUN65_RS16280	COG0567	Dehydrogenase, E1 component
CUN65_RS16285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUN65_RS16290	COG1053	succinate dehydrogenase
CUN65_RS16295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CUN65_RS16300	COG2009	succinate dehydrogenase
CUN65_RS16305	COG0372	Belongs to the citrate synthase family
CUN65_RS16310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CUN65_RS16320	COG1984	allophanate hydrolase subunit 2
CUN65_RS16325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CUN65_RS16330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CUN65_RS16350	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CUN65_RS16355	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CUN65_RS16360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CUN65_RS16365	COG2205	protein histidine kinase activity
CUN65_RS16370	COG0745	RESPONSE REGULATOR receiver
CUN65_RS16380	COG1982	Orn Lys Arg decarboxylase major
CUN65_RS16385	COG0531	amino acid
CUN65_RS16390	COG0033	Phosphoglucomutase
CUN65_RS16395	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CUN65_RS16400	COG0596	Alpha beta hydrolase
CUN65_RS16420	COG0735	belongs to the Fur family
CUN65_RS16445	COG1263	PTS System
CUN65_RS16445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS16445	COG2190	(PTS) system
CUN65_RS16455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CUN65_RS16460	COG1940	carbohydrate kinase activity
CUN65_RS16460	COG1846	Transcriptional regulator
CUN65_RS16465	COG0647	UMP catabolic process
CUN65_RS16470	COG0367	asparagine synthase
CUN65_RS16515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUN65_RS16520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CUN65_RS16525	COG1702	phosphate starvation-inducible protein PhoH
CUN65_RS16530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CUN65_RS16555	COG0765	amino acid transport
CUN65_RS16560	COG0765	amino acid transport
CUN65_RS16565	COG1126	abc transporter atp-binding protein
CUN65_RS16570	COG1957	nucleoside hydrolase
CUN65_RS16575	COG2888	peptidyl-tyrosine sulfation
CUN65_RS16590	COG1466	dna polymerase III delta subunit
CUN65_RS16600	COG0799	negative regulation of ribosome biogenesis
CUN65_RS16610	COG0768	penicillin binding
CUN65_RS16615	COG0772	Belongs to the SEDS family
CUN65_RS16620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUN65_RS16625	COG1686	Belongs to the peptidase S11 family
CUN65_RS16635	COG0321	lipoyl(octanoyl) transferase activity
CUN65_RS16640	COG0583	DNA-binding transcription factor activity
CUN65_RS16645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CUN65_RS16650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CUN65_RS16655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUN65_RS16675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS16680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS16700	COG3069	C4-dicarboxylate transmembrane transporter activity
CUN65_RS16705	COG3719	Belongs to the RNase T2 family
CUN65_RS16710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS16715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUN65_RS16720	COG0006	proline dipeptidase activity
CUN65_RS16725	COG1363	Peptidase, m42
CUN65_RS16730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUN65_RS16730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS16730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS16735	COG2207	Transcriptional regulator
CUN65_RS16745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CUN65_RS16750	COG1063	alcohol dehydrogenase
CUN65_RS16770	COG0583	DNA-binding transcription factor activity
CUN65_RS16775	COG3969	phosphoadenosine phosphosulfate
CUN65_RS16780	COG1475	DNA binding
CUN65_RS16785	COG0436	Aminotransferase
CUN65_RS16790	COG0235	Class ii aldolase
CUN65_RS16795	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CUN65_RS16815	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CUN65_RS16830	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS16835	COG1129	ABC transporter
CUN65_RS16840	COG0371	Dehydrogenase
CUN65_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS16860	COG2879	small protein
CUN65_RS16865	COG1966	Carbon starvation protein
CUN65_RS16870	COG2050	protein possibly involved in aromatic compounds catabolism
CUN65_RS16875	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS16880	COG1535	isochorismatase
CUN65_RS16880	COG3433	isochorismatase activity
CUN65_RS16885	COG1021	2,3-dihydroxybenzoate-AMP ligase
CUN65_RS16890	COG1169	isochorismate synthase
CUN65_RS16895	COG4592	Periplasmic binding protein
CUN65_RS16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS16910	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS16915	COG1120	ATPase activity
CUN65_RS16925	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CUN65_RS16925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUN65_RS16930	COG3251	PFAM MbtH domain protein
CUN65_RS16935	COG2382	esterase
CUN65_RS16940	COG4771	TonB-dependent receptor
CUN65_RS16945	COG2977	Belongs to the P-Pant transferase superfamily
CUN65_RS16950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUN65_RS16955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUN65_RS16960	COG1121	(ABC) transporter
CUN65_RS16975	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CUN65_RS16980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUN65_RS17010	COG0601	transmembrane transport
CUN65_RS17015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUN65_RS17020	COG0444	Belongs to the ABC transporter superfamily
CUN65_RS17025	COG4608	Belongs to the ABC transporter superfamily
CUN65_RS17095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CUN65_RS17125	COG4774	siderophore transport
CUN65_RS17145	COG2315	Protein conserved in bacteria
CUN65_RS17165	COG0477	Major facilitator Superfamily
CUN65_RS17170	COG0668	transmembrane transport
CUN65_RS17175	COG1609	Transcriptional regulator
CUN65_RS17180	COG0673	inositol 2-dehydrogenase activity
CUN65_RS17190	COG2211	Major facilitator Superfamily
CUN65_RS17195	COG1113	amino acid transport
CUN65_RS17220	COG2246	polysaccharide biosynthetic process
CUN65_RS17345	COG1783	phage Terminase large subunit
CUN65_RS17455	COG0305	Participates in initiation and elongation during chromosome replication
CUN65_RS17475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUN65_RS17505	COG3723	Recombinational DNA repair protein, rece pathway
CUN65_RS17575	COG0582	viral genome integration into host DNA
CUN65_RS17635	COG2501	S4 domain
CUN65_RS17640	COG1263	PTS System
CUN65_RS17640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS17640	COG2190	(PTS) system
CUN65_RS17645	COG1609	Transcriptional regulator
CUN65_RS17650	COG1988	membrane-bound metal-dependent
CUN65_RS17660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUN65_RS17665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUN65_RS17670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CUN65_RS17675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CUN65_RS17690	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CUN65_RS17695	COG4181	ATPase activity
CUN65_RS17700	COG2755	lipolytic protein G-D-S-L family
CUN65_RS17705	COG0300	oxidoreductase activity
CUN65_RS17710	COG3118	belongs to the thioredoxin family
CUN65_RS17715	COG0390	transport system, permease component
CUN65_RS17720	COG4619	ABC transporter
CUN65_RS17730	COG0330	HflC and HflK could
CUN65_RS17735	COG1585	Membrane protein implicated in regulation of membrane protease activity
CUN65_RS17745	COG2217	Heavy metal translocating P-type atpase
CUN65_RS17750	COG3735	TraB family
CUN65_RS17755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUN65_RS17760	COG0737	Belongs to the 5'-nucleotidase family
CUN65_RS17765	COG2223	nitrite transmembrane transporter activity
CUN65_RS17770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUN65_RS17770	COG4651	solute:proton antiporter activity
CUN65_RS17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUN65_RS17780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CUN65_RS17790	COG0326	Molecular chaperone. Has ATPase activity
CUN65_RS17795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CUN65_RS17800	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CUN65_RS17810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CUN65_RS17815	COG2832	Protein of unknown function (DUF454)
CUN65_RS17820	COG3923	Primosomal replication protein n
CUN65_RS17830	COG3264	Mechanosensitive ion channel
CUN65_RS17830	COG1196	nuclear chromosome segregation
CUN65_RS17835	COG1309	transcriptional regulator
CUN65_RS17840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS17845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUN65_RS17860	COG0110	maltose O-acetyltransferase activity
CUN65_RS17880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CUN65_RS17890	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CUN65_RS17900	COG1609	Transcriptional regulator
CUN65_RS17905	COG2364	Membrane
CUN65_RS17910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUN65_RS17930	COG3695	enzyme binding
CUN65_RS17935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CUN65_RS17940	COG1946	Acyl-CoA thioesterase
CUN65_RS17945	COG0004	ammonium transporteR
CUN65_RS17950	COG0347	Belongs to the P(II) protein family
CUN65_RS17955	COG1132	(ABC) transporter
CUN65_RS17960	COG1132	(ABC) transporter
CUN65_RS17965	COG1522	sequence-specific DNA binding
CUN65_RS17975	COG0561	phosphatase activity
CUN65_RS17980	COG4533	DNA binding
CUN65_RS17985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CUN65_RS17995	COG3657	addiction module killer protein
CUN65_RS18000	COG0824	Thioesterase
CUN65_RS18005	COG1555	photosystem II stabilization
CUN65_RS18015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUN65_RS18020	COG0776	regulation of translation
CUN65_RS18025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CUN65_RS18040	COG0544	peptidyl-prolyl cis-trans isomerase activity
CUN65_RS18045	COG0271	Belongs to the BolA IbaG family
CUN65_RS18050	COG3056	Lipoprotein
CUN65_RS18055	COG2223	nitrite transmembrane transporter activity
CUN65_RS18060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CUN65_RS18065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CUN65_RS18070	COG1845	cytochrome c oxidase, subunit III
CUN65_RS18075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CUN65_RS18080	COG0109	protoheme IX farnesyltransferase activity
CUN65_RS18085	COG2814	Major facilitator Superfamily
CUN65_RS18095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CUN65_RS18100	COG0693	protein deglycase activity
CUN65_RS18115	COG0142	geranyltranstransferase activity
CUN65_RS18120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUN65_RS18125	COG0667	Aldo Keto reductase
CUN65_RS18130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CUN65_RS18135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUN65_RS18140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CUN65_RS18145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUN65_RS18145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUN65_RS18150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CUN65_RS18155	COG4238	major outer membrane lipoprotein
CUN65_RS18160	COG3248	Nucleoside-binding outer membrane protein
CUN65_RS18175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUN65_RS18180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUN65_RS18185	COG1862	Preprotein translocase
CUN65_RS18200	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CUN65_RS18205	COG0450	alkyl hydroperoxide reductase
CUN65_RS18220	COG0366	Alpha amylase catalytic
CUN65_RS18235	COG5002	protein histidine kinase activity
CUN65_RS18245	COG0420	3'-5' exonuclease activity
CUN65_RS18250	COG0419	ATPase involved in DNA repair
CUN65_RS18255	COG1940	carbohydrate kinase activity
CUN65_RS18265	COG3123	guanosine phosphorylase activity
CUN65_RS18270	COG4126	flavin adenine dinucleotide binding
CUN65_RS18280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CUN65_RS18285	COG1671	Belongs to the UPF0178 family
CUN65_RS18290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUN65_RS18295	COG3706	GGDEF domain
CUN65_RS18320	COG1181	Belongs to the D-alanine--D-alanine ligase family
CUN65_RS18340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CUN65_RS18345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUN65_RS18350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUN65_RS18365	COG0113	porphobilinogen synthase activity
CUN65_RS18375	COG2175	clavaminate synthase activity
CUN65_RS18380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUN65_RS18385	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CUN65_RS18390	COG4521	taurine ABC transporter
CUN65_RS18395	COG2040	homocysteine
CUN65_RS18400	COG0833	amino acid
CUN65_RS18405	COG0628	permease
CUN65_RS18420	COG5001	Diguanylate cyclase
CUN65_RS18420	COG3300	MHYT domain
CUN65_RS18435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CUN65_RS18470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CUN65_RS18475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CUN65_RS18480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CUN65_RS18490	COG1073	alpha beta
CUN65_RS18500	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUN65_RS18505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUN65_RS18510	COG2991	Protein conserved in bacteria
CUN65_RS18525	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CUN65_RS18530	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CUN65_RS18545	COG3034	peptidoglycan biosynthetic process
CUN65_RS18550	COG0121	glutamine amidotransferase
CUN65_RS18560	COG1960	acyl-CoA dehydrogenase activity
CUN65_RS18565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUN65_RS18615	COG2177	Part of the ABC transporter FtsEX involved in
CUN65_RS18635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS18640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS18645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CUN65_RS18650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUN65_RS18655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUN65_RS18665	COG0736	holo-[acyl-carrier-protein] synthase activity
CUN65_RS18675	COG3210	domain, Protein
CUN65_RS18685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUN65_RS18690	COG1596	polysaccharide export
CUN65_RS18725	COG2226	methyltransferase
CUN65_RS18730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUN65_RS18735	COG0741	lytic transglycosylase activity
CUN65_RS18735	COG1388	LysM domain
CUN65_RS18740	COG2226	methyltransferase
CUN65_RS18745	COG3021	interspecies interaction between organisms
CUN65_RS18750	COG2814	Major facilitator Superfamily
CUN65_RS18755	COG0583	DNA-binding transcription factor activity
CUN65_RS18800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CUN65_RS18810	COG2011	ABC-type metal ion transport system permease component
CUN65_RS18815	COG1464	Belongs to the NlpA lipoprotein family
CUN65_RS18825	COG1720	tRNA m6t6A37 methyltransferase activity
CUN65_RS18835	COG3015	lipoprotein NlpE involved in copper resistance
CUN65_RS18840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CUN65_RS18855	COG4568	rho-dependent transcription termination
CUN65_RS18860	COG0037	tRNA processing
CUN65_RS18865	COG0346	lactoylglutathione lyase activity
CUN65_RS18870	COG1982	Orn Lys Arg decarboxylase major
CUN65_RS18875	COG0825	malonyl-CoA metabolic process
CUN65_RS18885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CUN65_RS18890	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUN65_RS18895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUN65_RS18900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUN65_RS18915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUN65_RS18920	COG0750	zinc metalloprotease
CUN65_RS18925	COG0575	Belongs to the CDS family
CUN65_RS18935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CUN65_RS18980	COG3835	regulator
CUN65_RS18985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUN65_RS18990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CUN65_RS18995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUN65_RS19005	COG2860	membrane
CUN65_RS19010	COG0316	Belongs to the HesB IscA family
CUN65_RS19020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CUN65_RS19025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUN65_RS19030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CUN65_RS19035	COG1120	ATPase activity
CUN65_RS19040	COG4774	siderophore transport
CUN65_RS19045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUN65_RS19055	COG1643	Atp-dependent helicase
CUN65_RS19060	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CUN65_RS19065	COG1489	DNA binding
CUN65_RS19080	COG0617	tRNA 3'-terminal CCA addition
CUN65_RS19085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUN65_RS19095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CUN65_RS19100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CUN65_RS19110	COG3121	Chaperone
CUN65_RS19115	COG3188	usher protein
CUN65_RS19120	COG3539	Fimbrial protein
CUN65_RS19130	COG3539	Fimbrial protein
CUN65_RS19140	COG0726	polysaccharide deacetylase
CUN65_RS19145	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS19150	COG0842	Transport permease protein
CUN65_RS19155	COG1131	(ABC) transporter
CUN65_RS19160	COG0288	reversible hydration of carbon dioxide
CUN65_RS19170	COG4993	Dehydrogenase
CUN65_RS19185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CUN65_RS19200	COG1049	propionate catabolic process, 2-methylcitrate cycle
CUN65_RS19205	COG3064	Membrane
CUN65_RS19215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUN65_RS19220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUN65_RS19225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CUN65_RS19230	COG2186	Transcriptional regulator
CUN65_RS19235	COG1113	amino acid transport
CUN65_RS19240	COG2211	Major facilitator Superfamily
CUN65_RS19245	COG3940	Belongs to the glycosyl hydrolase 43 family
CUN65_RS19250	COG3725	Membrane protein required for beta-lactamase induction
CUN65_RS19255	COG3023	N-Acetylmuramoyl-L-alanine amidase
CUN65_RS19265	COG4969	Belongs to the N-Me-Phe pilin family
CUN65_RS19270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUN65_RS19275	COG1459	type II secretion system
CUN65_RS19280	COG0516	GMP reductase activity
CUN65_RS19290	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CUN65_RS19295	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CUN65_RS19300	COG0494	nUDIX hydrolase
CUN65_RS19305	COG0653	protein targeting
CUN65_RS19315	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CUN65_RS19320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CUN65_RS19325	COG0849	cell division
CUN65_RS19335	COG1181	Belongs to the D-alanine--D-alanine ligase family
CUN65_RS19350	COG0772	Belongs to the SEDS family
CUN65_RS19360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUN65_RS19365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUN65_RS19370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUN65_RS19375	COG0768	penicillin binding
CUN65_RS19395	COG1609	Transcriptional regulator
CUN65_RS19405	COG0028	Belongs to the TPP enzyme family
CUN65_RS19420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUN65_RS19440	COG2814	Major facilitator Superfamily
CUN65_RS19460	COG1178	ABC-type Fe3 transport system permease component
CUN65_RS19475	COG0586	Pfam SNARE associated Golgi protein
CUN65_RS19485	COG1069	ribulokinase activity
CUN65_RS19490	COG2160	L-arabinose isomerase activity
CUN65_RS19495	COG0235	Class ii aldolase
CUN65_RS19500	COG0417	DNA replication proofreading
CUN65_RS19505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CUN65_RS19510	COG0564	pseudouridine synthase activity
CUN65_RS19515	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CUN65_RS19520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CUN65_RS19525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUN65_RS19530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CUN65_RS19540	COG2967	ApaG domain
CUN65_RS19545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CUN65_RS19560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUN65_RS19560	COG0475	glutathione-regulated potassium exporter activity
CUN65_RS19585	COG0505	Belongs to the CarA family
CUN65_RS19595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CUN65_RS19600	COG1047	Peptidyl-prolyl cis-trans
CUN65_RS19615	COG0196	riboflavin kinase activity
CUN65_RS19630	COG0268	Binds directly to 16S ribosomal RNA
CUN65_RS19635	COG0583	DNA-binding transcription factor activity
CUN65_RS19640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CUN65_RS19660	COG1584	GPR1 FUN34 yaaH family protein
CUN65_RS19665	COG0477	Major facilitator Superfamily
CUN65_RS19670	COG0521	Mo-molybdopterin cofactor biosynthetic process
CUN65_RS19680	COG1115	amino acid carrier protein
CUN65_RS19695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CUN65_RS19705	COG0527	aspartate kinase activity
CUN65_RS19705	COG0460	homoserine dehydrogenase
CUN65_RS19715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CUN65_RS19725	COG0745	RESPONSE REGULATOR receiver
CUN65_RS19730	COG3045	CreA protein
CUN65_RS19735	COG3708	Transcriptional regulator
CUN65_RS19735	COG2207	Transcriptional regulator
CUN65_RS19740	COG0406	alpha-ribazole phosphatase activity
CUN65_RS19745	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CUN65_RS19750	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CUN65_RS19755	COG0741	lytic transglycosylase activity
CUN65_RS19760	COG0488	(ABC) transporter
CUN65_RS19785	COG0560	Phosphoserine phosphatase
CUN65_RS19795	COG3726	membrane protein affecting hemolysin expression
CUN65_RS19805	COG3539	Fimbrial protein
CUN65_RS19835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CUN65_RS19845	COG1328	CTP reductase activity
CUN65_RS19855	COG0084	hydrolase, TatD family'
CUN65_RS19860	COG4667	esterase of the alpha-beta hydrolase superfamily
CUN65_RS19865	COG5487	UPF0391 membrane protein
CUN65_RS19870	COG2823	Periplasmic or secreted lipoprotein
CUN65_RS19875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CUN65_RS19880	COG1011	Hydrolase
CUN65_RS19885	COG0456	acetyltransferase
CUN65_RS19890	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CUN65_RS19895	COG2813	Specifically methylates the guanine in position
CUN65_RS19925	COG4114	ferric iron reductase
CUN65_RS19930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS19930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CUN65_RS19935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUN65_RS19940	COG2197	response regulator
CUN65_RS19950	COG2966	Psort location CytoplasmicMembrane, score
CUN65_RS19955	COG3610	response to peptide
CUN65_RS19960	COG1846	Transcriptional regulator
CUN65_RS19965	COG1764	response to oxidative stress
CUN65_RS19975	COG1484	DNA-dependent DNA replication
CUN65_RS19995	COG0840	transmembrane signaling receptor activity
CUN65_RS20000	COG1846	Transcriptional regulator
CUN65_RS20005	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUN65_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS20015	COG3384	dioxygenase
CUN65_RS20025	COG3971	2-oxopent-4-enoate hydratase activity
CUN65_RS20045	COG2368	4-hydroxyphenylacetate
CUN65_RS20050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUN65_RS20055	COG1349	DNA-binding transcription factor activity
CUN65_RS20060	COG1966	Carbon starvation protein
CUN65_RS20065	COG2879	small protein
CUN65_RS20070	COG0523	cobalamin synthesis protein
CUN65_RS20085	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS20095	COG2733	membrane
CUN65_RS20105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS20115	COG0640	Transcriptional regulator
CUN65_RS20135	COG0583	DNA-binding transcription factor activity
CUN65_RS20140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUN65_RS20150	COG5457	Domain of unknown function (DUF1127)
CUN65_RS20155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUN65_RS20180	COG2850	peptidyl-arginine hydroxylation
CUN65_RS20185	COG0740	serine-type endopeptidase activity
CUN65_RS20190	COG4566	intracellular signal transduction
CUN65_RS20195	COG4191	Histidine kinase
CUN65_RS20215	COG1335	isochorismatase
CUN65_RS20240	COG1401	restriction endodeoxyribonuclease activity
CUN65_RS20250	COG2211	Major facilitator Superfamily
CUN65_RS20260	COG1609	Transcriptional regulator
CUN65_RS20315	COG1715	Restriction endonuclease
CUN65_RS20335	COG2003	Belongs to the UPF0758 family
CUN65_RS20360	COG2378	regulation of single-species biofilm formation
CUN65_RS20370	COG3596	GTP binding
CUN65_RS20425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CUN65_RS20450	COG0582	viral genome integration into host DNA
CUN65_RS20475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CUN65_RS20490	COG1414	Transcriptional regulator
CUN65_RS20495	COG3507	Belongs to the glycosyl hydrolase 43 family
CUN65_RS20500	COG2211	Major facilitator Superfamily
CUN65_RS20505	COG0129	dihydroxy-acid dehydratase activity
CUN65_RS20510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUN65_RS20515	COG2731	YhcH YjgK YiaL family protein
CUN65_RS20520	COG2235	arginine
CUN65_RS20535	COG1288	antiporter activity
CUN65_RS20540	COG1438	arginine binding
CUN65_RS20555	COG0540	Belongs to the ATCase OTCase family
CUN65_RS20565	COG0251	oxidation-reduction process
CUN65_RS20570	COG3397	chitin binding
CUN65_RS20615	COG1263	PTS System
CUN65_RS20615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CUN65_RS20620	COG0366	Alpha amylase catalytic
CUN65_RS20630	COG0602	queuosine metabolic process
CUN65_RS20635	COG3711	transcriptional antiterminator
CUN65_RS20635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS20655	COG3964	amidohydrolase
CUN65_RS20690	COG3783	Cytochrome b(562)
CUN65_RS20695	COG0312	modulator of DNA gyrase
CUN65_RS20700	COG3028	Belongs to the UPF0307 family
CUN65_RS20705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUN65_RS20720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS20725	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS20730	COG1129	ABC transporter
CUN65_RS20735	COG1879	ABC-type sugar transport system periplasmic component
CUN65_RS20745	COG2105	PFAM AIG2 family protein
CUN65_RS20750	COG2911	Protein conserved in bacteria
CUN65_RS20755	COG0729	surface antigen
CUN65_RS20760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUN65_RS20765	COG1253	flavin adenine dinucleotide binding
CUN65_RS20780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CUN65_RS20785	COG1218	3'(2'),5'-bisphosphate nucleotidase
CUN65_RS20795	COG1733	regulation of RNA biosynthetic process
CUN65_RS20800	COG0702	epimerase
CUN65_RS20810	COG0697	spore germination
CUN65_RS20815	COG0840	transmembrane signaling receptor activity
CUN65_RS20825	COG1113	amino acid transport
CUN65_RS20835	COG0545	Peptidyl-prolyl cis-trans isomerase
CUN65_RS20840	COG3061	Opacity-associated protein A
CUN65_RS20845	COG0697	spore germination
CUN65_RS20850	COG0359	binds to the 23S rRNA
CUN65_RS20855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CUN65_RS20860	COG2965	DNA replication, synthesis of RNA primer
CUN65_RS20900	COG3037	sugar-specific permease SgaT UlaA
CUN65_RS20915	COG1073	alpha beta
CUN65_RS20920	COG3650	response to hydrogen peroxide
CUN65_RS20935	COG1960	acyl-CoA dehydrogenase activity
CUN65_RS20940	COG0477	Major facilitator Superfamily
CUN65_RS20945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUN65_RS20950	COG0557	exoribonuclease II activity
CUN65_RS20955	COG1959	2 iron, 2 sulfur cluster binding
CUN65_RS20965	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CUN65_RS20970	COG0330	HflC and HflK could
CUN65_RS20975	COG0330	HflC and HflK could
CUN65_RS20980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUN65_RS20985	COG1923	regulation of RNA biosynthetic process
CUN65_RS20990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CUN65_RS20995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CUN65_RS21005	COG0802	atpase or kinase
CUN65_RS21010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CUN65_RS21010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUN65_RS21015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUN65_RS21050	COG3264	Mechanosensitive ion channel
CUN65_RS21050	COG1511	domain protein
CUN65_RS21060	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CUN65_RS21065	COG1053	succinate dehydrogenase
CUN65_RS21070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUN65_RS21075	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CUN65_RS21085	COG0583	DNA-binding transcription factor activity
CUN65_RS21110	COG5510	response to toxic substance
CUN65_RS21135	COG3366	ferrous iron transmembrane transporter activity
CUN65_RS21140	COG0700	Nucleoside recognition
CUN65_RS21145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CUN65_RS21150	COG0459	protein refolding
CUN65_RS21160	COG0531	amino acid
CUN65_RS21165	COG3030	protein affecting phage T7 exclusion by the F plasmid
CUN65_RS21170	COG1027	Aspartate ammonia-lyase
CUN65_RS21175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CUN65_RS21190	COG1309	transcriptional regulator
CUN65_RS21210	COG3647	Membrane
CUN65_RS21240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUN65_RS21250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CUN65_RS21255	COG0009	L-threonylcarbamoyladenylate synthase
CUN65_RS21260	COG0551	DNA topoisomerase type I activity
CUN65_RS21265	COG2922	Belongs to the Smg family
CUN65_RS21270	COG0758	DNA mediated transformation
CUN65_RS21275	COG0242	peptide deformylase activity
CUN65_RS21280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CUN65_RS21285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CUN65_RS21285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUN65_RS21295	COG1970	mechanosensitive ion channel activity
CUN65_RS21300	COG3036	rescue of stalled ribosome
CUN65_RS21305	COG0789	Transcriptional regulator
CUN65_RS21320	COG0202	RNA polymerase activity
CUN65_RS21330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CUN65_RS21345	COG0201	protein transport
CUN65_RS21355	COG1841	ribosomal large subunit assembly
CUN65_RS21370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CUN65_RS21375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CUN65_RS21405	COG0255	Belongs to the universal ribosomal protein uL29 family
CUN65_RS21410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CUN65_RS21450	COG0051	transcription antitermination factor activity, RNA binding
CUN65_RS21490	COG2168	tRNA wobble position uridine thiolation
CUN65_RS21495	COG2923	Belongs to the DsrF TusC family
CUN65_RS21500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CUN65_RS21505	COG2964	Protein conserved in bacteria
CUN65_RS21510	COG0545	Peptidyl-prolyl cis-trans isomerase
CUN65_RS21520	COG1047	Peptidyl-prolyl cis-trans
CUN65_RS21525	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CUN65_RS21530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUN65_RS21530	COG0475	glutathione-regulated potassium exporter activity
CUN65_RS21535	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUN65_RS21540	COG0488	(ABC) transporter
CUN65_RS21550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUN65_RS21560	COG0679	Auxin Efflux Carrier
CUN65_RS21590	COG0429	hydrolase of the alpha beta-hydrolase fold
CUN65_RS21595	COG3089	Belongs to the UPF0270 family
CUN65_RS21600	COG3954	Phosphoribulokinase
CUN65_RS21605	COG1765	OsmC-like protein
CUN65_RS21625	COG1289	transmembrane transporter activity
CUN65_RS21630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUN65_RS21640	COG2184	nucleotidyltransferase activity
CUN65_RS21655	COG0738	Major facilitator superfamily
CUN65_RS21660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUN65_RS21670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CUN65_RS21670	COG1648	precorrin-2 dehydrogenase activity
CUN65_RS21680	COG0180	Tryptophanyl-tRNA synthetase
CUN65_RS21690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUN65_RS21695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CUN65_RS21700	COG3266	domain, Protein
CUN65_RS21705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CUN65_RS21710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CUN65_RS21740	COG4972	Pilus assembly protein
CUN65_RS21745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CUN65_RS21750	COG0494	nUDIX hydrolase
CUN65_RS21765	COG1011	Hydrolase
CUN65_RS21770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CUN65_RS21775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CUN65_RS21780	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CUN65_RS21785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CUN65_RS21800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CUN65_RS21805	COG2183	response to ionizing radiation
CUN65_RS21810	COG1918	ferrous iron import across plasma membrane
CUN65_RS21830	COG1040	competence protein
CUN65_RS21840	COG2610	gluconate transmembrane transporter activity
CUN65_RS21845	COG1640	4-alpha-glucanotransferase
CUN65_RS21850	COG0058	SHG alpha-glucan phosphorylase activity
CUN65_RS21855	COG2909	trisaccharide binding
CUN65_RS21860	COG1349	DNA-binding transcription factor activity
CUN65_RS21865	COG0705	Rhomboid family
CUN65_RS21870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUN65_RS21875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CUN65_RS21880	COG0058	SHG alpha-glucan phosphorylase activity
CUN65_RS21885	COG0297	glycogen (starch) synthase activity
CUN65_RS21890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CUN65_RS21895	COG1523	belongs to the glycosyl hydrolase 13 family
CUN65_RS21900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CUN65_RS21905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CUN65_RS21910	COG2095	MarC family integral membrane protein
CUN65_RS21915	COG2610	gluconate transmembrane transporter activity
CUN65_RS21920	COG3265	gluconokinase activity
CUN65_RS21925	COG1609	Transcriptional regulator
CUN65_RS21930	COG1741	Belongs to the pirin family
CUN65_RS21935	COG0673	inositol 2-dehydrogenase activity
CUN65_RS21945	COG1247	-acetyltransferase
CUN65_RS21950	COG0405	Gamma-glutamyltransferase
CUN65_RS21960	COG0584	glycerophosphoryl diester phosphodiesterase
CUN65_RS21990	COG0411	ABC transporter
CUN65_RS21995	COG4177	L-phenylalanine transmembrane transporter activity
CUN65_RS22005	COG0683	leucine binding
CUN65_RS22010	COG0456	acetyltransferase
CUN65_RS22015	COG0683	leucine binding
CUN65_RS22020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUN65_RS22025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CUN65_RS22030	COG2177	Part of the ABC transporter FtsEX involved in
CUN65_RS22035	COG2884	Cell division ATP-binding protein ftsE
CUN65_RS22040	COG0552	protein localization to endoplasmic reticulum
CUN65_RS22045	COG0742	ribosomal rna small subunit methyltransferase
CUN65_RS22050	COG3776	membrane
CUN65_RS22060	COG3714	YhhN family
CUN65_RS22065	COG2217	Heavy metal translocating P-type atpase
CUN65_RS22090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CUN65_RS22100	COG0628	permease
CUN65_RS22120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUN65_RS22140	COG1216	Glycosyl transferase, family 2
CUN65_RS22165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS22175	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS22180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUN65_RS22190	COG3479	Phenolic acid decarboxylase
CUN65_RS22195	COG0583	DNA-binding transcription factor activity
CUN65_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS22220	COG2205	protein histidine kinase activity
CUN65_RS22225	COG0745	RESPONSE REGULATOR receiver
CUN65_RS22230	COG1276	copper resistance
CUN65_RS22235	COG2372	response to copper ion
CUN65_RS22240	COG3667	copper resistance
CUN65_RS22245	COG2132	Multicopper oxidase
CUN65_RS22255	COG0739	heme binding
CUN65_RS22285	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUN65_RS22350	COG2081	HI0933 family
CUN65_RS22355	COG0306	phosphate transporter
CUN65_RS22365	COG0589	response to stress
CUN65_RS22370	COG0742	ribosomal rna small subunit methyltransferase
CUN65_RS22375	COG0339	signal peptide processing
CUN65_RS22380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CUN65_RS22385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUN65_RS22405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS22415	COG2197	response regulator
CUN65_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
CUN65_RS22425	COG0583	DNA-binding transcription factor activity
CUN65_RS22430	COG1295	ribonuclease BN
CUN65_RS22435	COG0477	Major facilitator Superfamily
CUN65_RS22440	COG2982	Protein involved in outer membrane biogenesis
CUN65_RS22445	COG2200	EAL domain
CUN65_RS22455	COG0612	Peptidase, M16
CUN65_RS22460	COG1301	dicarboxylic acid transport
CUN65_RS22465	COG2199	diguanylate cyclase activity
CUN65_RS22465	COG2200	EAL domain
CUN65_RS22470	COG3118	belongs to the thioredoxin family
CUN65_RS22470	COG0457	Tetratricopeptide repeat
CUN65_RS22475	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CUN65_RS22510	COG2194	sulfuric ester hydrolase activity
CUN65_RS22520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CUN65_RS22550	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CUN65_RS22560	COG1739	Uncharacterized protein family UPF0029
CUN65_RS22565	COG0006	proline dipeptidase activity
CUN65_RS22575	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUN65_RS22575	COG1024	Enoyl-CoA hydratase
CUN65_RS22580	COG0183	Belongs to the thiolase family
CUN65_RS22585	COG0751	glycine-tRNA ligase activity
CUN65_RS22590	COG0752	glycyl-tRNA synthetase alpha subunit
CUN65_RS22600	COG3274	enterobacterial common antigen metabolic process
CUN65_RS22605	COG1070	Carbohydrate kinase
CUN65_RS22610	COG2115	Belongs to the xylose isomerase family
CUN65_RS22620	COG4213	ABC transporter substrate-binding protein
CUN65_RS22630	COG4214	carbohydrate transport
CUN65_RS22635	COG2207	Transcriptional regulator
CUN65_RS22635	COG1609	Transcriptional regulator
CUN65_RS22640	COG2992	FlgJ-related protein
CUN65_RS22650	COG0366	Alpha amylase catalytic
CUN65_RS22655	COG3977	Valine--pyruvate aminotransferase
CUN65_RS22660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUN65_RS22680	COG1012	belongs to the aldehyde dehydrogenase family
CUN65_RS22685	COG1940	carbohydrate kinase activity
CUN65_RS22690	COG3276	selenocysteine insertion sequence binding
CUN65_RS22700	COG0625	glutathione transferase activity
CUN65_RS22705	COG2213	PTS system mannitol-specific
CUN65_RS22705	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUN65_RS22715	COG3722	fumarate hydratase activity
CUN65_RS22730	COG3188	usher protein
CUN65_RS22735	COG3121	Chaperone
CUN65_RS22740	COG3539	Fimbrial protein
CUN65_RS22750	COG2186	Transcriptional regulator
CUN65_RS22765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CUN65_RS22775	COG0583	DNA-binding transcription factor activity
CUN65_RS22780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUN65_RS22790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUN65_RS22795	COG3978	acetolactate synthase activity
CUN65_RS22820	COG3085	chromosome segregation
CUN65_RS22870	COG4206	TonB-dependent receptor
CUN65_RS22875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUN65_RS22895	COG0583	DNA-binding transcription factor activity
CUN65_RS22900	COG0165	Argininosuccinate lyase
CUN65_RS22910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CUN65_RS22915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUN65_RS22920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CUN65_RS22925	COG2207	Transcriptional regulator
CUN65_RS22935	COG0371	Dehydrogenase
CUN65_RS22940	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CUN65_RS22950	COG0527	aspartate kinase activity
CUN65_RS22950	COG0460	homoserine dehydrogenase
CUN65_RS22955	COG0626	cystathionine gamma-synthase activity
CUN65_RS22970	COG0254	rRNA binding
CUN65_RS22975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUN65_RS22980	COG1609	Transcriptional regulator
CUN65_RS22985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUN65_RS23000	COG1575	Belongs to the MenA family. Type 1 subfamily
CUN65_RS23005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CUN65_RS23010	COG3074	FtsZ-dependent cytokinesis
CUN65_RS23015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CUN65_RS23025	COG1494	fructose-1,6-bisphosphatase
CUN65_RS23035	COG3152	Membrane
CUN65_RS23045	COG0149	triose-phosphate isomerase activity
CUN65_RS23055	COG2134	cdp-diacylglycerol pyrophosphatase
CUN65_RS23065	COG0205	6-phosphofructokinase activity
CUN65_RS23075	COG3678	ATP-independent chaperone mediated protein folding
CUN65_RS23080	COG0745	RESPONSE REGULATOR receiver
CUN65_RS23085	COG2205	protein histidine kinase activity
CUN65_RS23090	COG2258	MOSC domain
CUN65_RS23095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUN65_RS23105	COG4977	sequence-specific DNA binding
CUN65_RS23105	COG1917	Cupin 2, conserved barrel domain protein
CUN65_RS23110	COG4977	sequence-specific DNA binding
CUN65_RS23120	COG1070	Carbohydrate kinase
CUN65_RS23125	COG4806	L-rhamnose isomerase
CUN65_RS23130	COG0235	Class ii aldolase
CUN65_RS23140	COG1129	ABC transporter
CUN65_RS23145	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS23155	COG1454	alcohol dehydrogenase
CUN65_RS23160	COG3254	rhamnose metabolic process
CUN65_RS23165	COG2211	Major facilitator Superfamily
CUN65_RS23185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUN65_RS23205	COG0243	molybdopterin cofactor binding
CUN65_RS23205	COG3383	formate dehydrogenase (NAD+) activity
CUN65_RS23210	COG0243	molybdopterin cofactor binding
CUN65_RS23210	COG3383	formate dehydrogenase (NAD+) activity
CUN65_RS23215	COG0437	4 iron, 4 sulfur cluster binding
CUN65_RS23220	COG2864	formate dehydrogenase
CUN65_RS23225	COG3058	Necessary for formate dehydrogenase activity
CUN65_RS23235	COG0456	acetyltransferase
CUN65_RS23250	COG1011	Hydrolase
CUN65_RS23255	COG1349	DNA-binding transcription factor activity
CUN65_RS23260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUN65_RS23270	COG3684	Belongs to the aldolase LacD family
CUN65_RS23280	COG1501	Belongs to the glycosyl hydrolase 31 family
CUN65_RS23295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CUN65_RS23315	COG3852	Histidine kinase
CUN65_RS23330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUN65_RS23335	COG3078	GTPase activator activity
CUN65_RS23355	COG0204	Acyl-transferase
CUN65_RS23365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CUN65_RS23370	COG3084	Protein conserved in bacteria
CUN65_RS23375	COG0746	molybdenum cofactor guanylyltransferase activity
CUN65_RS23380	COG1763	Mo-molybdopterin cofactor biosynthetic process
CUN65_RS23405	COG2186	Transcriptional regulator
CUN65_RS23410	COG0477	Major facilitator Superfamily
CUN65_RS23415	COG1609	Transcriptional regulator
CUN65_RS23420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUN65_RS23430	COG1172	Belongs to the binding-protein-dependent transport system permease family
CUN65_RS23435	COG1129	ABC transporter
CUN65_RS23440	COG1869	D-ribose catabolic process
CUN65_RS23445	COG3158	transport of potassium into the cell
CUN65_RS23455	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CUN65_RS23460	COG2502	aspartate--ammonia ligase
CUN65_RS23465	COG1522	sequence-specific DNA binding
CUN65_RS23470	COG0716	FMN binding
CUN65_RS23480	COG0445	tRNA wobble uridine modification
CUN65_RS23485	COG0357	Ribosomal RNA small subunit methyltransferase G
CUN65_RS23490	COG3312	ion transport
CUN65_RS23495	COG0356	it plays a direct role in the translocation of protons across the membrane
CUN65_RS23505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CUN65_RS23510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CUN65_RS23525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CUN65_RS23530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CUN65_RS23535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CUN65_RS23550	COG3121	Chaperone
CUN65_RS23560	COG3539	Fimbrial protein
CUN65_RS23565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CUN65_RS23570	COG0573	inorganic phosphate transmembrane transporter activity
CUN65_RS23575	COG0581	inorganic phosphate transmembrane transporter activity
CUN65_RS23580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUN65_RS23585	COG0704	Plays a role in the regulation of phosphate uptake
CUN65_RS23590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUN65_RS23595	COG2252	PERMEase
CUN65_RS23600	COG0431	NADPH-dependent FMN reductase
CUN65_RS23605	COG2091	lysine biosynthetic process via aminoadipic acid
CUN65_RS23625	COG0706	membrane insertase activity
CUN65_RS23695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CUN65_RS23705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUN65_RS23780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUN65_RS23795	COG1702	phosphate starvation-inducible protein PhoH
CUN65_RS23960	COG3941	tape measure
CUN65_RS24050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUN65_RS24055	COG1475	DNA binding
CUN65_RS24060	COG1475	DNA binding
CUN65_RS24065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUN65_RS24175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUN65_RS24220	COG0328	RNA-DNA hybrid ribonuclease activity
CUN65_RS24240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUN65_RS24275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUN65_RS24280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUN65_RS24400	COG1192	Involved in chromosome partitioning
CUN65_RS24515	COG0210	DNA helicase
CUN65_RS24665	COG4245	von Willebrand factor, type A
CUN65_RS24670	COG4245	von Willebrand factor, type A
CUN65_RS24700	COG1358	cellular component organization or biogenesis
CUN65_RS24770	COG3328	transposase activity
CUN65_RS24805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CUN65_RS24860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CUN65_RS25005	COG0640	Transcriptional regulator
CUN65_RS25020	COG0786	glutamate:sodium symporter activity
CUN65_RS25050	COG3550	peptidyl-serine autophosphorylation
CUN65_RS25110	COG3039	Transposase
CUN65_RS25205	COG1196	nuclear chromosome segregation
CUN65_RS25225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUN65_RS25265	COG1252	NADH dehydrogenase
CUN65_RS25285	COG1454	alcohol dehydrogenase
CUN65_RS25295	COG1294	oxidase, subunit
CUN65_RS25300	COG1271	oxidase subunit
CUN65_RS25360	COG0642	Histidine kinase
CUN65_RS25400	COG2194	sulfuric ester hydrolase activity
CUN65_RS25410	COG2205	protein histidine kinase activity
CUN65_RS25500	COG0659	secondary active sulfate transmembrane transporter activity
CUN65_RS25505	COG0589	response to stress
CUN65_RS25510	COG1393	Belongs to the ArsC family
CUN65_RS25515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CUN65_RS25520	COG0640	Transcriptional regulator
CUN65_RS25525	COG0431	NADPH-dependent FMN reductase
CUN65_RS25530	COG2801	Transposase and inactivated derivatives
CUN65_RS25560	COG3039	Transposase
CUN65_RS25575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CUN65_RS25640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CUN65_RS25640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUN65_RS25660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUN65_RS25675	COG3157	Type VI secretion system effector, Hcp
CUN65_RS25855	COG2026	Addiction module toxin, RelE StbE family
CUN65_RS25860	COG3077	Addiction module antitoxin, RelB DinJ family
CUN65_RS25870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CUN65_RS25880	COG3547	Transposase (IS116 IS110 IS902 family)
CUN65_RS25885	COG2801	Transposase and inactivated derivatives
CUN65_RS25995	COG1609	Transcriptional regulator
CUN65_RS26005	COG2223	nitrite transmembrane transporter activity
CUN65_RS26010	COG0110	maltose O-acetyltransferase activity
CUN65_RS26025	COG3436	PFAM IS66 Orf2 family protein
CUN65_RS26030	COG4372	Transposase
CUN65_RS26160	COG2890	protein-(glutamine-N5) methyltransferase activity
CUN65_RS26220	COG0338	D12 class N6 adenine-specific DNA methyltransferase