locus-tag	class	description
ECWSU1_RS00010	COG0592	DNA-directed DNA polymerase activity
ECWSU1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ECWSU1_RS00025	COG0583	DNA-binding transcription factor activity
ECWSU1_RS00035	COG0561	phosphatase activity
ECWSU1_RS00040	COG2186	Transcriptional regulator
ECWSU1_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
ECWSU1_RS00050	COG0800	Aldolase
ECWSU1_RS00055	COG4948	Mandelate Racemase Muconate Lactonizing
ECWSU1_RS00060	COG2271	Major facilitator Superfamily
ECWSU1_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
ECWSU1_RS00070	COG5645	(Lipo)protein
ECWSU1_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
ECWSU1_RS00085	COG2985	domain, Protein
ECWSU1_RS00090	COG2188	Transcriptional regulator
ECWSU1_RS00105	COG2149	membrane
ECWSU1_RS00120	COG2610	gluconate transmembrane transporter activity
ECWSU1_RS00125	COG0583	DNA-binding transcription factor activity
ECWSU1_RS00135	COG2814	Major facilitator Superfamily
ECWSU1_RS00155	COG0028	Belongs to the TPP enzyme family
ECWSU1_RS00160	COG0440	acetolactate synthase activity
ECWSU1_RS00165	COG2197	response regulator
ECWSU1_RS00185	COG0596	Alpha beta hydrolase
ECWSU1_RS00195	COG0583	DNA-binding transcription factor activity
ECWSU1_RS00210	COG2814	Major facilitator Superfamily
ECWSU1_RS00220	COG0183	Belongs to the thiolase family
ECWSU1_RS00225	COG0667	Aldo Keto reductase
ECWSU1_RS00235	COG0697	spore germination
ECWSU1_RS00240	COG4580	involved in the transport of maltose and maltodextrins
ECWSU1_RS00245	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECWSU1_RS00250	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS00255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS00255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS00265	COG1609	Transcriptional regulator
ECWSU1_RS00285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS00295	COG0454	-acetyltransferase
ECWSU1_RS00300	COG1309	transcriptional regulator
ECWSU1_RS00310	COG1464	Belongs to the NlpA lipoprotein family
ECWSU1_RS00330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ECWSU1_RS00350	COG3272	Protein of unknown function (DUF1722)
ECWSU1_RS00355	COG2351	hydroxyisourate hydrolase activity
ECWSU1_RS00360	COG0789	Transcriptional regulator
ECWSU1_RS00375	COG0519	Catalyzes the synthesis of GMP from XMP
ECWSU1_RS00385	COG2211	Major facilitator Superfamily
ECWSU1_RS00390	COG1501	Belongs to the glycosyl hydrolase 31 family
ECWSU1_RS00395	COG2982	Protein involved in outer membrane biogenesis
ECWSU1_RS00400	COG2233	PERMEase
ECWSU1_RS00405	COG0786	glutamate:sodium symporter activity
ECWSU1_RS00410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECWSU1_RS00415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECWSU1_RS00420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECWSU1_RS00435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ECWSU1_RS00440	COG2860	membrane
ECWSU1_RS00445	COG1561	YicC-like family, N-terminal region
ECWSU1_RS00455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ECWSU1_RS00470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECWSU1_RS00475	COG2003	Belongs to the UPF0758 family
ECWSU1_RS00480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ECWSU1_RS00485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ECWSU1_RS00490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ECWSU1_RS00495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ECWSU1_RS00505	COG1519	Transferase
ECWSU1_RS00510	COG1216	Glycosyl transferase, family 2
ECWSU1_RS00515	COG0438	transferase activity, transferring glycosyl groups
ECWSU1_RS00520	COG0438	transferase activity, transferring glycosyl groups
ECWSU1_RS00525	COG0859	PFAM glycosyl transferase family 9
ECWSU1_RS00535	COG3307	-O-antigen
ECWSU1_RS00540	COG1215	transferase activity, transferring glycosyl groups
ECWSU1_RS00550	COG0859	PFAM glycosyl transferase family 9
ECWSU1_RS00555	COG0859	PFAM glycosyl transferase family 9
ECWSU1_RS00570	COG1063	alcohol dehydrogenase
ECWSU1_RS00585	COG2861	carbohydrate metabolic process
ECWSU1_RS00590	COG4942	peptidase
ECWSU1_RS00595	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ECWSU1_RS00600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECWSU1_RS00605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECWSU1_RS00610	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ECWSU1_RS00615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ECWSU1_RS00625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECWSU1_RS00630	COG2271	Major facilitator Superfamily
ECWSU1_RS00640	COG2186	Transcriptional regulator
ECWSU1_RS00655	COG3722	fumarate hydratase activity
ECWSU1_RS00665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS00665	COG2213	PTS system mannitol-specific
ECWSU1_RS00675	COG1566	PFAM secretion protein HlyD family protein
ECWSU1_RS00680	COG0625	glutathione transferase activity
ECWSU1_RS00690	COG3276	selenocysteine insertion sequence binding
ECWSU1_RS00695	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS00700	COG0583	DNA-binding transcription factor activity
ECWSU1_RS00705	COG3713	MltA-interacting MipA family protein
ECWSU1_RS00715	COG2211	Major facilitator Superfamily
ECWSU1_RS00725	COG0235	Class ii aldolase
ECWSU1_RS00730	COG3623	hexulose-6-phosphate isomerase
ECWSU1_RS00735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECWSU1_RS00740	COG1070	Carbohydrate kinase
ECWSU1_RS00755	COG2731	YhcH YjgK YiaL family protein
ECWSU1_RS00765	COG1414	Transcriptional regulator
ECWSU1_RS00770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECWSU1_RS00775	COG3977	Valine--pyruvate aminotransferase
ECWSU1_RS00780	COG0366	Alpha amylase catalytic
ECWSU1_RS00785	COG2992	FlgJ-related protein
ECWSU1_RS00790	COG2207	Transcriptional regulator
ECWSU1_RS00790	COG1609	Transcriptional regulator
ECWSU1_RS00795	COG4214	carbohydrate transport
ECWSU1_RS00805	COG4213	ABC transporter substrate-binding protein
ECWSU1_RS00810	COG2115	Belongs to the xylose isomerase family
ECWSU1_RS00815	COG1070	Carbohydrate kinase
ECWSU1_RS00820	COG1335	isochorismatase
ECWSU1_RS00830	COG3274	enterobacterial common antigen metabolic process
ECWSU1_RS00840	COG0752	glycyl-tRNA synthetase alpha subunit
ECWSU1_RS00845	COG0751	glycine-tRNA ligase activity
ECWSU1_RS00850	COG0488	(ABC) transporter
ECWSU1_RS00855	COG2944	sequence-specific DNA binding
ECWSU1_RS00870	COG1278	Cold shock
ECWSU1_RS00875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECWSU1_RS00885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECWSU1_RS00895	COG1609	Transcriptional regulator
ECWSU1_RS00900	COG2885	chlorophyll binding
ECWSU1_RS00905	COG0243	molybdopterin cofactor binding
ECWSU1_RS00910	COG0456	acetyltransferase
ECWSU1_RS00915	COG2818	Glycosylase
ECWSU1_RS00920	COG5571	outer membrane autotransporter
ECWSU1_RS00925	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS00930	COG2194	sulfuric ester hydrolase activity
ECWSU1_RS00940	COG0747	negative chemotaxis
ECWSU1_RS00945	COG0601	transmembrane transport
ECWSU1_RS00950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECWSU1_RS00955	COG0444	Belongs to the ABC transporter superfamily
ECWSU1_RS00960	COG4608	Belongs to the ABC transporter superfamily
ECWSU1_RS00965	COG1072	(Pantothenic acid kinase))
ECWSU1_RS01005	COG0250	Participates in transcription elongation, termination and antitermination
ECWSU1_RS01050	COG3706	GGDEF domain
ECWSU1_RS01060	COG2022	thiamine diphosphate biosynthetic process
ECWSU1_RS01065	COG2104	thiamine diphosphate biosynthetic process
ECWSU1_RS01070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECWSU1_RS01085	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ECWSU1_RS01095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ECWSU1_RS01105	COG3068	Protein conserved in bacteria
ECWSU1_RS01150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECWSU1_RS01160	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ECWSU1_RS01180	COG1187	pseudouridine synthase activity
ECWSU1_RS01195	COG0527	aspartate kinase activity
ECWSU1_RS01220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECWSU1_RS01225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECWSU1_RS01235	COG3223	Belongs to the PsiE family
ECWSU1_RS01240	COG3833	ABC-type maltose transport systems, permease component
ECWSU1_RS01260	COG4580	involved in the transport of maltose and maltodextrins
ECWSU1_RS01270	COG3161	chorismate lyase activity
ECWSU1_RS01280	COG2937	Belongs to the GPAT DAPAT family
ECWSU1_RS01285	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECWSU1_RS01290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECWSU1_RS01295	COG0534	Mate efflux family protein
ECWSU1_RS01300	COG3237	CsbD-like
ECWSU1_RS01305	COG0735	belongs to the Fur family
ECWSU1_RS01320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECWSU1_RS01330	COG0604	alcohol dehydrogenase
ECWSU1_RS01335	COG0305	Participates in initiation and elongation during chromosome replication
ECWSU1_RS01355	COG1448	Aminotransferase
ECWSU1_RS01360	COG3700	Belongs to the class B bacterial acid phosphatase family
ECWSU1_RS01365	COG0432	Pfam Uncharacterised protein family UPF0047
ECWSU1_RS01370	COG2315	Protein conserved in bacteria
ECWSU1_RS01380	COG0629	single-stranded DNA binding
ECWSU1_RS01390	COG2199	diguanylate cyclase activity
ECWSU1_RS01395	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECWSU1_RS01405	COG0789	Transcriptional regulator
ECWSU1_RS01415	COG2252	PERMEase
ECWSU1_RS01420	COG0025	NhaP-type Na H and K H
ECWSU1_RS01425	COG0583	DNA-binding transcription factor activity
ECWSU1_RS01435	COG1346	cytolysis
ECWSU1_RS01440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECWSU1_RS01445	COG3162	membrane
ECWSU1_RS01455	COG1301	dicarboxylic acid transport
ECWSU1_RS01460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECWSU1_RS01485	COG0191	fructose-bisphosphate aldolase activity
ECWSU1_RS01500	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS01505	COG1129	ABC transporter
ECWSU1_RS01510	COG0784	Response regulator, receiver
ECWSU1_RS01510	COG4191	Histidine kinase
ECWSU1_RS01515	COG1940	carbohydrate kinase activity
ECWSU1_RS01520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECWSU1_RS01525	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS01530	COG1129	ABC transporter
ECWSU1_RS01535	COG1879	ABC-type sugar transport system periplasmic component
ECWSU1_RS01540	COG1737	Transcriptional regulator
ECWSU1_RS01545	COG0698	ribose 5-phosphate isomerase
ECWSU1_RS01555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECWSU1_RS01560	COG0456	acetyltransferase
ECWSU1_RS01565	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ECWSU1_RS01570	COG3454	Phosphonate metabolism
ECWSU1_RS01575	COG4778	phosphonate C-P lyase system protein PhnL
ECWSU1_RS01580	COG4107	phosphonate C-P lyase system protein PhnK
ECWSU1_RS01585	COG3627	carbon phosphorus lyase activity
ECWSU1_RS01590	COG3626	phosphonate metabolism
ECWSU1_RS01595	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECWSU1_RS01600	COG3624	Phosphonate C-P lyase system protein PhnG
ECWSU1_RS01605	COG2188	Transcriptional regulator
ECWSU1_RS01610	COG3639	organic phosphonate transmembrane transporter activity
ECWSU1_RS01615	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ECWSU1_RS01625	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ECWSU1_RS01630	COG2824	Alkylphosphonate utilization operon protein PhnA
ECWSU1_RS01635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ECWSU1_RS01655	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ECWSU1_RS01685	COG1309	transcriptional regulator
ECWSU1_RS01690	COG4232	protein-disulfide reductase activity
ECWSU1_RS01700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECWSU1_RS01705	COG1027	Aspartate ammonia-lyase
ECWSU1_RS01710	COG3030	protein affecting phage T7 exclusion by the F plasmid
ECWSU1_RS01715	COG0531	amino acid
ECWSU1_RS01735	COG1509	lysine 2,3-aminomutase activity
ECWSU1_RS01745	COG5510	response to toxic substance
ECWSU1_RS01775	COG0583	DNA-binding transcription factor activity
ECWSU1_RS01780	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ECWSU1_RS01785	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ECWSU1_RS01790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECWSU1_RS01795	COG1053	succinate dehydrogenase
ECWSU1_RS01800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ECWSU1_RS01810	COG3264	Mechanosensitive ion channel
ECWSU1_RS01810	COG1511	domain protein
ECWSU1_RS01825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ECWSU1_RS01845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECWSU1_RS01850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECWSU1_RS01850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECWSU1_RS01855	COG0802	atpase or kinase
ECWSU1_RS01865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ECWSU1_RS01870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ECWSU1_RS01875	COG1923	regulation of RNA biosynthetic process
ECWSU1_RS01880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECWSU1_RS01885	COG0330	HflC and HflK could
ECWSU1_RS01890	COG0330	HflC and HflK could
ECWSU1_RS01895	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECWSU1_RS01905	COG1959	2 iron, 2 sulfur cluster binding
ECWSU1_RS01910	COG0557	exoribonuclease II activity
ECWSU1_RS01915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECWSU1_RS01920	COG0477	Major facilitator Superfamily
ECWSU1_RS01925	COG1960	acyl-CoA dehydrogenase activity
ECWSU1_RS01940	COG3650	response to hydrogen peroxide
ECWSU1_RS01945	COG1073	alpha beta
ECWSU1_RS02000	COG2965	DNA replication, synthesis of RNA primer
ECWSU1_RS02005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECWSU1_RS02010	COG0359	binds to the 23S rRNA
ECWSU1_RS02015	COG0697	spore germination
ECWSU1_RS02020	COG3061	Opacity-associated protein A
ECWSU1_RS02025	COG0545	Peptidyl-prolyl cis-trans isomerase
ECWSU1_RS02030	COG1113	amino acid transport
ECWSU1_RS02040	COG0840	transmembrane signaling receptor activity
ECWSU1_RS02045	COG0697	spore germination
ECWSU1_RS02055	COG0702	epimerase
ECWSU1_RS02060	COG1733	regulation of RNA biosynthetic process
ECWSU1_RS02070	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECWSU1_RS02075	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECWSU1_RS02085	COG1253	flavin adenine dinucleotide binding
ECWSU1_RS02090	COG2211	Major facilitator Superfamily
ECWSU1_RS02095	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS02105	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS02110	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS02115	COG1609	Transcriptional regulator
ECWSU1_RS02125	COG0729	surface antigen
ECWSU1_RS02130	COG2911	Protein conserved in bacteria
ECWSU1_RS02135	COG2105	PFAM AIG2 family protein
ECWSU1_RS02150	COG1879	ABC-type sugar transport system periplasmic component
ECWSU1_RS02155	COG1129	ABC transporter
ECWSU1_RS02160	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS02165	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS02175	COG0583	DNA-binding transcription factor activity
ECWSU1_RS02185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECWSU1_RS02190	COG3028	Belongs to the UPF0307 family
ECWSU1_RS02195	COG0312	modulator of DNA gyrase
ECWSU1_RS02230	COG3964	amidohydrolase
ECWSU1_RS02250	COG3711	transcriptional antiterminator
ECWSU1_RS02250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS02255	COG3077	Addiction module antitoxin, RelB DinJ family
ECWSU1_RS02275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS02275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS02275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS02300	COG0366	Alpha amylase catalytic
ECWSU1_RS02305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS02305	COG1263	PTS System
ECWSU1_RS02310	COG1609	Transcriptional regulator
ECWSU1_RS02320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ECWSU1_RS02325	COG0251	oxidation-reduction process
ECWSU1_RS02335	COG0540	Belongs to the ATCase OTCase family
ECWSU1_RS02340	COG1438	arginine binding
ECWSU1_RS02345	COG1288	antiporter activity
ECWSU1_RS02360	COG2235	arginine
ECWSU1_RS02365	COG2731	YhcH YjgK YiaL family protein
ECWSU1_RS02370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECWSU1_RS02375	COG0129	dihydroxy-acid dehydratase activity
ECWSU1_RS02380	COG2211	Major facilitator Superfamily
ECWSU1_RS02385	COG3507	Belongs to the glycosyl hydrolase 43 family
ECWSU1_RS02390	COG1414	Transcriptional regulator
ECWSU1_RS02395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECWSU1_RS02420	COG0582	viral genome integration into host DNA
ECWSU1_RS02480	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ECWSU1_RS02500	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS02530	COG0402	S-adenosylhomocysteine deaminase activity
ECWSU1_RS02555	COG1609	Transcriptional regulator
ECWSU1_RS02565	COG2211	Major facilitator Superfamily
ECWSU1_RS02570	COG0346	lactoylglutathione lyase activity
ECWSU1_RS02575	COG1349	DNA-binding transcription factor activity
ECWSU1_RS02580	COG0740	serine-type endopeptidase activity
ECWSU1_RS02585	COG2850	peptidyl-arginine hydroxylation
ECWSU1_RS02610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECWSU1_RS02630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS02635	COG0583	DNA-binding transcription factor activity
ECWSU1_RS02640	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS02655	COG0640	Transcriptional regulator
ECWSU1_RS02675	COG2733	membrane
ECWSU1_RS02690	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS02710	COG0523	cobalamin synthesis protein
ECWSU1_RS02715	COG2879	small protein
ECWSU1_RS02720	COG1966	Carbon starvation protein
ECWSU1_RS02730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECWSU1_RS02735	COG2368	4-hydroxyphenylacetate
ECWSU1_RS02755	COG3971	2-oxopent-4-enoate hydratase activity
ECWSU1_RS02765	COG3384	dioxygenase
ECWSU1_RS02770	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS02775	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECWSU1_RS02780	COG1846	Transcriptional regulator
ECWSU1_RS02785	COG0840	transmembrane signaling receptor activity
ECWSU1_RS02820	COG1484	DNA-dependent DNA replication
ECWSU1_RS02830	COG1764	response to oxidative stress
ECWSU1_RS02835	COG1846	Transcriptional regulator
ECWSU1_RS02840	COG1309	transcriptional regulator
ECWSU1_RS02845	COG3610	response to peptide
ECWSU1_RS02850	COG2966	Psort location CytoplasmicMembrane, score
ECWSU1_RS02855	COG2197	response regulator
ECWSU1_RS02860	COG2197	response regulator
ECWSU1_RS02865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECWSU1_RS02870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS02875	COG4114	ferric iron reductase
ECWSU1_RS02905	COG2813	Specifically methylates the guanine in position
ECWSU1_RS02910	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ECWSU1_RS02915	COG0456	acetyltransferase
ECWSU1_RS02920	COG1011	Hydrolase
ECWSU1_RS02930	COG2823	Periplasmic or secreted lipoprotein
ECWSU1_RS02935	COG5487	UPF0391 membrane protein
ECWSU1_RS02940	COG4667	esterase of the alpha-beta hydrolase superfamily
ECWSU1_RS02945	COG0084	hydrolase, TatD family'
ECWSU1_RS02950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECWSU1_RS02955	COG1328	CTP reductase activity
ECWSU1_RS02965	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ECWSU1_RS02975	COG0813	purine-nucleoside phosphorylase activity
ECWSU1_RS02990	COG3188	usher protein
ECWSU1_RS02995	COG3121	Chaperone
ECWSU1_RS03005	COG3539	Fimbrial protein
ECWSU1_RS03010	COG3539	Fimbrial protein
ECWSU1_RS03020	COG3726	membrane protein affecting hemolysin expression
ECWSU1_RS03025	COG0560	Phosphoserine phosphatase
ECWSU1_RS03030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECWSU1_RS03040	COG0604	alcohol dehydrogenase
ECWSU1_RS03050	COG0488	(ABC) transporter
ECWSU1_RS03055	COG0741	lytic transglycosylase activity
ECWSU1_RS03060	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ECWSU1_RS03065	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ECWSU1_RS03070	COG0406	alpha-ribazole phosphatase activity
ECWSU1_RS03075	COG2207	Transcriptional regulator
ECWSU1_RS03075	COG3708	Transcriptional regulator
ECWSU1_RS03080	COG3045	CreA protein
ECWSU1_RS03085	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS03090	COG2205	protein histidine kinase activity
ECWSU1_RS03095	COG4452	Inner membrane protein CreD
ECWSU1_RS03100	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS03105	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ECWSU1_RS03110	COG0460	homoserine dehydrogenase
ECWSU1_RS03110	COG0527	aspartate kinase activity
ECWSU1_RS03120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECWSU1_RS03130	COG3022	response to hydroperoxide
ECWSU1_RS03135	COG1115	amino acid carrier protein
ECWSU1_RS03145	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECWSU1_RS03150	COG0477	Major facilitator Superfamily
ECWSU1_RS03155	COG1584	GPR1 FUN34 yaaH family protein
ECWSU1_RS03175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ECWSU1_RS03180	COG0583	DNA-binding transcription factor activity
ECWSU1_RS03185	COG0268	Binds directly to 16S ribosomal RNA
ECWSU1_RS03190	COG0196	riboflavin kinase activity
ECWSU1_RS03205	COG1047	Peptidyl-prolyl cis-trans
ECWSU1_RS03210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ECWSU1_RS03215	COG2140	Oxalate decarboxylase
ECWSU1_RS03225	COG3716	PTS system mannose fructose sorbose family IID component
ECWSU1_RS03230	COG3715	PTS system
ECWSU1_RS03235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS03250	COG1609	Transcriptional regulator
ECWSU1_RS03260	COG0505	Belongs to the CarA family
ECWSU1_RS03275	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECWSU1_RS03280	COG0475	glutathione-regulated potassium exporter activity
ECWSU1_RS03280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECWSU1_RS03290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ECWSU1_RS03295	COG2967	ApaG domain
ECWSU1_RS03305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ECWSU1_RS03310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECWSU1_RS03315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECWSU1_RS03320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECWSU1_RS03325	COG0564	pseudouridine synthase activity
ECWSU1_RS03330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ECWSU1_RS03335	COG0417	DNA replication proofreading
ECWSU1_RS03340	COG0235	Class ii aldolase
ECWSU1_RS03345	COG2160	L-arabinose isomerase activity
ECWSU1_RS03350	COG1069	ribulokinase activity
ECWSU1_RS03360	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS03370	COG1178	ABC-type Fe3 transport system permease component
ECWSU1_RS03375	COG4143	(ABC) transporter
ECWSU1_RS03390	COG2814	Major facilitator Superfamily
ECWSU1_RS03410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ECWSU1_RS03420	COG0028	Belongs to the TPP enzyme family
ECWSU1_RS03430	COG1609	Transcriptional regulator
ECWSU1_RS03435	COG2001	Belongs to the MraZ family
ECWSU1_RS03450	COG0768	penicillin binding
ECWSU1_RS03455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECWSU1_RS03460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECWSU1_RS03465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECWSU1_RS03475	COG0772	Belongs to the SEDS family
ECWSU1_RS03485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECWSU1_RS03490	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECWSU1_RS03500	COG0849	cell division
ECWSU1_RS03505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECWSU1_RS03510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ECWSU1_RS03520	COG0653	protein targeting
ECWSU1_RS03525	COG0494	nUDIX hydrolase
ECWSU1_RS03530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ECWSU1_RS03535	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ECWSU1_RS03545	COG0516	GMP reductase activity
ECWSU1_RS03550	COG1459	type II secretion system
ECWSU1_RS03555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECWSU1_RS03560	COG4969	Belongs to the N-Me-Phe pilin family
ECWSU1_RS03570	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECWSU1_RS03575	COG3725	Membrane protein required for beta-lactamase induction
ECWSU1_RS03580	COG3940	Belongs to the glycosyl hydrolase 43 family
ECWSU1_RS03585	COG2211	Major facilitator Superfamily
ECWSU1_RS03590	COG1113	amino acid transport
ECWSU1_RS03600	COG2186	Transcriptional regulator
ECWSU1_RS03605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECWSU1_RS03610	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECWSU1_RS03615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECWSU1_RS03625	COG3064	Membrane
ECWSU1_RS03640	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ECWSU1_RS03645	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ECWSU1_RS03655	COG2132	Multicopper oxidase
ECWSU1_RS03660	COG4993	Dehydrogenase
ECWSU1_RS03665	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ECWSU1_RS03670	COG0288	reversible hydration of carbon dioxide
ECWSU1_RS03675	COG1131	(ABC) transporter
ECWSU1_RS03680	COG0842	Transport permease protein
ECWSU1_RS03685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS03690	COG0726	polysaccharide deacetylase
ECWSU1_RS03695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ECWSU1_RS03700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ECWSU1_RS03710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECWSU1_RS03715	COG0617	tRNA 3'-terminal CCA addition
ECWSU1_RS03730	COG1489	DNA binding
ECWSU1_RS03735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ECWSU1_RS03740	COG1643	Atp-dependent helicase
ECWSU1_RS03745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECWSU1_RS03750	COG4774	siderophore transport
ECWSU1_RS03755	COG1120	ATPase activity
ECWSU1_RS03760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECWSU1_RS03765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS03770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ECWSU1_RS03785	COG2860	membrane
ECWSU1_RS03790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECWSU1_RS03800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ECWSU1_RS03810	COG3835	regulator
ECWSU1_RS03840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ECWSU1_RS03855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECWSU1_RS03865	COG0575	Belongs to the CDS family
ECWSU1_RS03870	COG0750	zinc metalloprotease
ECWSU1_RS03875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECWSU1_RS03885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECWSU1_RS03890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ECWSU1_RS03900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECWSU1_RS03905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ECWSU1_RS03920	COG1982	Orn Lys Arg decarboxylase major
ECWSU1_RS03925	COG0346	lactoylglutathione lyase activity
ECWSU1_RS03930	COG0037	tRNA processing
ECWSU1_RS03935	COG4568	rho-dependent transcription termination
ECWSU1_RS03950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECWSU1_RS03955	COG3015	lipoprotein NlpE involved in copper resistance
ECWSU1_RS03960	COG0442	prolyl-tRNA aminoacylation
ECWSU1_RS03965	COG1720	tRNA m6t6A37 methyltransferase activity
ECWSU1_RS03975	COG1464	Belongs to the NlpA lipoprotein family
ECWSU1_RS03980	COG2011	ABC-type metal ion transport system permease component
ECWSU1_RS03990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECWSU1_RS04030	COG0583	DNA-binding transcription factor activity
ECWSU1_RS04035	COG2814	Major facilitator Superfamily
ECWSU1_RS04040	COG3021	interspecies interaction between organisms
ECWSU1_RS04045	COG2226	methyltransferase
ECWSU1_RS04050	COG0741	lytic transglycosylase activity
ECWSU1_RS04050	COG1388	LysM domain
ECWSU1_RS04055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECWSU1_RS04060	COG2226	methyltransferase
ECWSU1_RS04070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECWSU1_RS04085	COG0444	Belongs to the ABC transporter superfamily
ECWSU1_RS04090	COG4608	Belongs to the ABC transporter superfamily
ECWSU1_RS04105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECWSU1_RS04115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECWSU1_RS04120	COG1960	acyl-CoA dehydrogenase activity
ECWSU1_RS04130	COG0121	glutamine amidotransferase
ECWSU1_RS04135	COG3034	peptidoglycan biosynthetic process
ECWSU1_RS04150	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECWSU1_RS04155	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECWSU1_RS04170	COG2991	Protein conserved in bacteria
ECWSU1_RS04175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ECWSU1_RS04180	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECWSU1_RS04190	COG1073	alpha beta
ECWSU1_RS04200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECWSU1_RS04205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ECWSU1_RS04210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ECWSU1_RS04220	COG0582	viral genome integration into host DNA
ECWSU1_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS04285	COG0583	DNA-binding transcription factor activity
ECWSU1_RS04300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECWSU1_RS04315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ECWSU1_RS04325	COG3188	usher protein
ECWSU1_RS04330	COG3121	Chaperone
ECWSU1_RS04340	COG3706	GGDEF domain
ECWSU1_RS04345	COG0628	permease
ECWSU1_RS04350	COG0833	amino acid
ECWSU1_RS04355	COG2040	homocysteine
ECWSU1_RS04360	COG4521	taurine ABC transporter
ECWSU1_RS04365	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ECWSU1_RS04370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECWSU1_RS04375	COG2175	clavaminate synthase activity
ECWSU1_RS04385	COG0113	porphobilinogen synthase activity
ECWSU1_RS04400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECWSU1_RS04410	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ECWSU1_RS04430	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECWSU1_RS04450	COG1785	Belongs to the alkaline phosphatase family
ECWSU1_RS04460	COG3706	GGDEF domain
ECWSU1_RS04465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECWSU1_RS04470	COG1671	Belongs to the UPF0178 family
ECWSU1_RS04475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ECWSU1_RS04485	COG4126	flavin adenine dinucleotide binding
ECWSU1_RS04490	COG3123	guanosine phosphorylase activity
ECWSU1_RS04500	COG1940	carbohydrate kinase activity
ECWSU1_RS04505	COG0419	ATPase involved in DNA repair
ECWSU1_RS04510	COG0420	3'-5' exonuclease activity
ECWSU1_RS04520	COG5002	protein histidine kinase activity
ECWSU1_RS04535	COG0366	Alpha amylase catalytic
ECWSU1_RS04540	COG1335	isochorismatase
ECWSU1_RS04550	COG1228	amidohydrolase
ECWSU1_RS04555	COG0450	alkyl hydroperoxide reductase
ECWSU1_RS04560	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ECWSU1_RS04575	COG1862	Preprotein translocase
ECWSU1_RS04580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECWSU1_RS04585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECWSU1_RS04600	COG3248	Nucleoside-binding outer membrane protein
ECWSU1_RS04605	COG4238	major outer membrane lipoprotein
ECWSU1_RS04610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ECWSU1_RS04615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECWSU1_RS04615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECWSU1_RS04620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ECWSU1_RS04625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ECWSU1_RS04630	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECWSU1_RS04635	COG0667	Aldo Keto reductase
ECWSU1_RS04640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ECWSU1_RS04645	COG0142	geranyltranstransferase activity
ECWSU1_RS04665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECWSU1_RS04675	COG2814	Major facilitator Superfamily
ECWSU1_RS04680	COG0109	protoheme IX farnesyltransferase activity
ECWSU1_RS04685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECWSU1_RS04690	COG1845	cytochrome c oxidase, subunit III
ECWSU1_RS04695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECWSU1_RS04700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECWSU1_RS04705	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS04710	COG3056	Lipoprotein
ECWSU1_RS04715	COG0271	Belongs to the BolA IbaG family
ECWSU1_RS04720	COG0544	peptidyl-prolyl cis-trans isomerase activity
ECWSU1_RS04730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ECWSU1_RS04735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECWSU1_RS04740	COG0776	regulation of translation
ECWSU1_RS04745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECWSU1_RS04750	COG1555	photosystem II stabilization
ECWSU1_RS04755	COG0824	Thioesterase
ECWSU1_RS04760	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ECWSU1_RS04765	COG4533	DNA binding
ECWSU1_RS04770	COG0561	phosphatase activity
ECWSU1_RS04780	COG1522	sequence-specific DNA binding
ECWSU1_RS04785	COG1132	(ABC) transporter
ECWSU1_RS04790	COG1132	(ABC) transporter
ECWSU1_RS04795	COG0347	Belongs to the P(II) protein family
ECWSU1_RS04800	COG0004	ammonium transporteR
ECWSU1_RS04805	COG1946	Acyl-CoA thioesterase
ECWSU1_RS04810	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECWSU1_RS04815	COG3695	enzyme binding
ECWSU1_RS04830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECWSU1_RS04835	COG2364	Membrane
ECWSU1_RS04840	COG1609	Transcriptional regulator
ECWSU1_RS04860	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ECWSU1_RS04870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ECWSU1_RS04890	COG0110	maltose O-acetyltransferase activity
ECWSU1_RS04905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECWSU1_RS04910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS04915	COG1309	transcriptional regulator
ECWSU1_RS04920	COG1196	nuclear chromosome segregation
ECWSU1_RS04920	COG3264	Mechanosensitive ion channel
ECWSU1_RS04930	COG3923	Primosomal replication protein n
ECWSU1_RS04935	COG2832	Protein of unknown function (DUF454)
ECWSU1_RS04940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ECWSU1_RS04950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ECWSU1_RS04955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ECWSU1_RS04960	COG0326	Molecular chaperone. Has ATPase activity
ECWSU1_RS04970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ECWSU1_RS04975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECWSU1_RS04980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECWSU1_RS04980	COG4651	solute:proton antiporter activity
ECWSU1_RS04985	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS05000	COG3735	TraB family
ECWSU1_RS05015	COG1585	Membrane protein implicated in regulation of membrane protease activity
ECWSU1_RS05020	COG0330	HflC and HflK could
ECWSU1_RS05025	COG4619	ABC transporter
ECWSU1_RS05030	COG0390	transport system, permease component
ECWSU1_RS05035	COG3118	belongs to the thioredoxin family
ECWSU1_RS05040	COG0300	oxidoreductase activity
ECWSU1_RS05045	COG2755	lipolytic protein G-D-S-L family
ECWSU1_RS05050	COG4181	ATPase activity
ECWSU1_RS05055	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ECWSU1_RS05070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECWSU1_RS05075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECWSU1_RS05085	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECWSU1_RS05090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECWSU1_RS05100	COG1988	membrane-bound metal-dependent
ECWSU1_RS05105	COG1609	Transcriptional regulator
ECWSU1_RS05110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS05110	COG1263	PTS System
ECWSU1_RS05110	COG2190	(PTS) system
ECWSU1_RS05115	COG2501	S4 domain
ECWSU1_RS05195	COG1113	amino acid transport
ECWSU1_RS05200	COG2211	Major facilitator Superfamily
ECWSU1_RS05210	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS05215	COG1609	Transcriptional regulator
ECWSU1_RS05220	COG0668	transmembrane transport
ECWSU1_RS05225	COG0477	Major facilitator Superfamily
ECWSU1_RS05240	COG0778	Nitroreductase
ECWSU1_RS05245	COG2315	Protein conserved in bacteria
ECWSU1_RS05260	COG2207	Transcriptional regulator
ECWSU1_RS05285	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ECWSU1_RS05295	COG2207	Transcriptional regulator
ECWSU1_RS05310	COG1566	PFAM secretion protein HlyD family protein
ECWSU1_RS05315	COG1652	LysM domain
ECWSU1_RS05320	COG3753	Protein conserved in bacteria
ECWSU1_RS05325	COG2207	Transcriptional regulator
ECWSU1_RS05330	COG0300	oxidoreductase activity
ECWSU1_RS05335	COG4977	sequence-specific DNA binding
ECWSU1_RS05340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS05355	COG2188	Transcriptional regulator
ECWSU1_RS05370	COG0386	Belongs to the glutathione peroxidase family
ECWSU1_RS05385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECWSU1_RS05390	COG0668	transmembrane transport
ECWSU1_RS05410	COG0583	DNA-binding transcription factor activity
ECWSU1_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS05425	COG0456	acetyltransferase
ECWSU1_RS05445	COG1733	regulation of RNA biosynthetic process
ECWSU1_RS05450	COG2194	sulfuric ester hydrolase activity
ECWSU1_RS05475	COG2197	response regulator
ECWSU1_RS05480	COG0784	Response regulator, receiver
ECWSU1_RS05480	COG2198	Histidine kinase
ECWSU1_RS05480	COG2205	protein histidine kinase activity
ECWSU1_RS05485	COG3141	response to X-ray
ECWSU1_RS05490	COG3713	MltA-interacting MipA family protein
ECWSU1_RS05495	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS05515	COG0477	Major facilitator Superfamily
ECWSU1_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS05525	COG0583	DNA-binding transcription factor activity
ECWSU1_RS05530	COG0583	DNA-binding transcription factor activity
ECWSU1_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS05545	COG1335	isochorismatase
ECWSU1_RS05555	COG0753	catalase activity
ECWSU1_RS05575	COG5001	Diguanylate cyclase
ECWSU1_RS05575	COG3300	MHYT domain
ECWSU1_RS05585	COG0456	acetyltransferase
ECWSU1_RS05630	COG1309	transcriptional regulator
ECWSU1_RS05635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECWSU1_RS05695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECWSU1_RS05705	COG2977	Belongs to the P-Pant transferase superfamily
ECWSU1_RS05710	COG4771	TonB-dependent receptor
ECWSU1_RS05715	COG2382	esterase
ECWSU1_RS05720	COG3251	PFAM MbtH domain protein
ECWSU1_RS05725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECWSU1_RS05725	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECWSU1_RS05730	COG1120	ATPase activity
ECWSU1_RS05735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS05740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS05750	COG4592	Periplasmic binding protein
ECWSU1_RS05755	COG1169	isochorismate synthase
ECWSU1_RS05760	COG1021	2,3-dihydroxybenzoate-AMP ligase
ECWSU1_RS05765	COG1535	isochorismatase
ECWSU1_RS05765	COG3433	isochorismatase activity
ECWSU1_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS05775	COG2050	protein possibly involved in aromatic compounds catabolism
ECWSU1_RS05785	COG0700	Nucleoside recognition
ECWSU1_RS05790	COG3366	ferrous iron transmembrane transporter activity
ECWSU1_RS05795	COG1966	Carbon starvation protein
ECWSU1_RS05800	COG2879	small protein
ECWSU1_RS05810	COG0371	Dehydrogenase
ECWSU1_RS05815	COG1129	ABC transporter
ECWSU1_RS05820	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS05835	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ECWSU1_RS05855	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ECWSU1_RS05860	COG0235	Class ii aldolase
ECWSU1_RS05865	COG0436	Aminotransferase
ECWSU1_RS05870	COG0583	DNA-binding transcription factor activity
ECWSU1_RS05890	COG1063	alcohol dehydrogenase
ECWSU1_RS05895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECWSU1_RS05910	COG3719	Belongs to the RNase T2 family
ECWSU1_RS05915	COG3069	C4-dicarboxylate transmembrane transporter activity
ECWSU1_RS05930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ECWSU1_RS05935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECWSU1_RS05940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECWSU1_RS05945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ECWSU1_RS05950	COG0583	DNA-binding transcription factor activity
ECWSU1_RS05955	COG0321	lipoyl(octanoyl) transferase activity
ECWSU1_RS05965	COG1686	Belongs to the peptidase S11 family
ECWSU1_RS05970	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECWSU1_RS05975	COG0772	Belongs to the SEDS family
ECWSU1_RS05980	COG0768	penicillin binding
ECWSU1_RS05990	COG0799	negative regulation of ribosome biogenesis
ECWSU1_RS06000	COG1466	dna polymerase III delta subunit
ECWSU1_RS06015	COG2888	peptidyl-tyrosine sulfation
ECWSU1_RS06020	COG1957	nucleoside hydrolase
ECWSU1_RS06025	COG1126	abc transporter atp-binding protein
ECWSU1_RS06030	COG0765	amino acid transport
ECWSU1_RS06035	COG0765	amino acid transport
ECWSU1_RS06055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ECWSU1_RS06060	COG1702	phosphate starvation-inducible protein PhoH
ECWSU1_RS06070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECWSU1_RS06110	COG0367	asparagine synthase
ECWSU1_RS06115	COG0647	UMP catabolic process
ECWSU1_RS06120	COG1846	Transcriptional regulator
ECWSU1_RS06120	COG1940	carbohydrate kinase activity
ECWSU1_RS06125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECWSU1_RS06135	COG1263	PTS System
ECWSU1_RS06135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS06135	COG2190	(PTS) system
ECWSU1_RS06140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECWSU1_RS06155	COG0735	belongs to the Fur family
ECWSU1_RS06170	COG0596	Alpha beta hydrolase
ECWSU1_RS06175	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECWSU1_RS06180	COG0033	Phosphoglucomutase
ECWSU1_RS06185	COG0531	amino acid
ECWSU1_RS06190	COG1982	Orn Lys Arg decarboxylase major
ECWSU1_RS06195	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS06200	COG2205	protein histidine kinase activity
ECWSU1_RS06205	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ECWSU1_RS06210	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ECWSU1_RS06215	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ECWSU1_RS06235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECWSU1_RS06240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECWSU1_RS06245	COG1984	allophanate hydrolase subunit 2
ECWSU1_RS06255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ECWSU1_RS06260	COG0372	Belongs to the citrate synthase family
ECWSU1_RS06265	COG2009	succinate dehydrogenase
ECWSU1_RS06270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECWSU1_RS06275	COG1053	succinate dehydrogenase
ECWSU1_RS06280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECWSU1_RS06285	COG0567	Dehydrogenase, E1 component
ECWSU1_RS06290	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECWSU1_RS06295	COG0045	succinate-CoA ligase (ADP-forming) activity
ECWSU1_RS06300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECWSU1_RS06305	COG2188	Transcriptional regulator
ECWSU1_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS06310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS06315	COG0383	alpha-mannosidase activity
ECWSU1_RS06320	COG1271	oxidase subunit
ECWSU1_RS06325	COG1294	oxidase, subunit
ECWSU1_RS06330	COG4890	Cyd operon protein YbgT
ECWSU1_RS06335	COG3790	cyd operon protein YbgE
ECWSU1_RS06340	COG0824	Thioesterase
ECWSU1_RS06345	COG0811	peptide transport
ECWSU1_RS06350	COG0848	biopolymer transport protein
ECWSU1_RS06355	COG3064	Membrane
ECWSU1_RS06365	COG2885	chlorophyll binding
ECWSU1_RS06370	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECWSU1_RS06405	COG3201	nicotinamide mononucleotide transporter
ECWSU1_RS06410	COG1230	cation diffusion facilitator family transporter
ECWSU1_RS06420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECWSU1_RS06430	COG2017	converts alpha-aldose to the beta-anomer
ECWSU1_RS06435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ECWSU1_RS06440	COG1085	galactose-1-phosphate uridylyltransferase
ECWSU1_RS06445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECWSU1_RS06450	COG1119	ATPase activity
ECWSU1_RS06455	COG2005	Transcriptional regulator
ECWSU1_RS06455	COG3585	molybdate ion transport
ECWSU1_RS06465	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECWSU1_RS06470	COG4149	molybdate abc transporter
ECWSU1_RS06480	COG0561	phosphatase activity
ECWSU1_RS06485	COG2706	6-phosphogluconolactonase activity
ECWSU1_RS06490	COG4677	pectinesterase activity
ECWSU1_RS06500	COG0010	Belongs to the arginase family
ECWSU1_RS06510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ECWSU1_RS06515	COG2986	histidine ammonia-lyase
ECWSU1_RS06520	COG1881	PFAM PEBP family protein
ECWSU1_RS06525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECWSU1_RS06530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECWSU1_RS06535	COG0156	8-amino-7-oxononanoate synthase activity
ECWSU1_RS06550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ECWSU1_RS06570	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECWSU1_RS06575	COG0315	cyclic pyranopterin monophosphate synthase activity
ECWSU1_RS06580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECWSU1_RS06585	COG0314	molybdopterin synthase activity
ECWSU1_RS06590	COG0670	Belongs to the BI1 family
ECWSU1_RS06595	COG0392	lysyltransferase activity
ECWSU1_RS06600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECWSU1_RS06605	COG3568	Endonuclease Exonuclease Phosphatase
ECWSU1_RS06615	COG0842	Transport permease protein
ECWSU1_RS06620	COG0842	Transport permease protein
ECWSU1_RS06625	COG1131	(ABC) transporter
ECWSU1_RS06630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS06635	COG1309	transcriptional regulator
ECWSU1_RS06640	COG0513	Belongs to the DEAD box helicase family
ECWSU1_RS06665	COG3121	Chaperone
ECWSU1_RS06670	COG3539	Fimbrial protein
ECWSU1_RS06675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECWSU1_RS06685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECWSU1_RS06695	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ECWSU1_RS06700	COG0668	transmembrane transport
ECWSU1_RS06705	COG1126	abc transporter atp-binding protein
ECWSU1_RS06710	COG0765	amino acid transport
ECWSU1_RS06715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS06720	COG0783	Belongs to the Dps family
ECWSU1_RS06730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ECWSU1_RS06735	COG2194	sulfuric ester hydrolase activity
ECWSU1_RS06745	COG1321	iron dependent repressor
ECWSU1_RS06750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECWSU1_RS06755	COG1566	PFAM secretion protein HlyD family protein
ECWSU1_RS06760	COG2814	Major facilitator Superfamily
ECWSU1_RS06770	COG0667	Aldo Keto reductase
ECWSU1_RS06775	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS06780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS06785	COG2188	Transcriptional regulator
ECWSU1_RS06790	COG1376	ErfK ybiS ycfS ynhG family protein
ECWSU1_RS06795	COG0488	(ABC) transporter
ECWSU1_RS06805	COG2271	Major facilitator Superfamily
ECWSU1_RS06810	COG1609	Transcriptional regulator
ECWSU1_RS06820	COG0561	phosphatase activity
ECWSU1_RS06825	COG1882	Formate acetyltransferase
ECWSU1_RS06830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECWSU1_RS06835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECWSU1_RS06840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECWSU1_RS06850	COG1446	asparaginase
ECWSU1_RS06885	COG2133	pyrroloquinoline quinone binding
ECWSU1_RS06890	COG0625	glutathione transferase activity
ECWSU1_RS06895	COG1686	Belongs to the peptidase S11 family
ECWSU1_RS06900	COG1349	DNA-binding transcription factor activity
ECWSU1_RS06905	COG0671	phosphoesterase, PA-phosphatase related
ECWSU1_RS06915	COG2814	Major facilitator Superfamily
ECWSU1_RS06920	COG0561	phosphatase activity
ECWSU1_RS06925	COG0738	Major facilitator superfamily
ECWSU1_RS06930	COG3226	Transcriptional regulator
ECWSU1_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS06940	COG1393	Belongs to the ArsC family
ECWSU1_RS06945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECWSU1_RS06950	COG0640	Transcriptional regulator
ECWSU1_RS06955	COG2985	domain, Protein
ECWSU1_RS06955	COG0569	domain protein
ECWSU1_RS06970	COG0778	Nitroreductase
ECWSU1_RS06975	COG0189	ligase activity
ECWSU1_RS06985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECWSU1_RS06990	COG3842	ATPase activity
ECWSU1_RS06995	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECWSU1_RS07000	COG1177	transmembrane transport
ECWSU1_RS07010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECWSU1_RS07015	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS07020	COG5002	protein histidine kinase activity
ECWSU1_RS07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS07030	COG4160	amino acid transport
ECWSU1_RS07035	COG4215	(ABC) transporter
ECWSU1_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS07045	COG1126	abc transporter atp-binding protein
ECWSU1_RS07055	COG0393	Putative heavy-metal-binding
ECWSU1_RS07060	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECWSU1_RS07080	COG3031	protein transport across the cell outer membrane
ECWSU1_RS07090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECWSU1_RS07100	COG2165	general secretion pathway protein
ECWSU1_RS07110	COG2165	general secretion pathway protein
ECWSU1_RS07120	COG3156	type II secretion system protein K
ECWSU1_RS07135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ECWSU1_RS07150	COG3397	chitin binding
ECWSU1_RS07155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECWSU1_RS07160	COG0702	epimerase
ECWSU1_RS07165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECWSU1_RS07170	COG0028	Belongs to the TPP enzyme family
ECWSU1_RS07180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECWSU1_RS07185	COG1151	hydroxylamine reductase activity
ECWSU1_RS07190	COG2431	L-lysine efflux transmembrane transporter activity
ECWSU1_RS07200	COG3593	DNA synthesis involved in DNA repair
ECWSU1_RS07205	COG2990	Protein conserved in bacteria
ECWSU1_RS07210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS07220	COG1278	Cold shock
ECWSU1_RS07225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ECWSU1_RS07230	COG0542	response to heat
ECWSU1_RS07240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ECWSU1_RS07245	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ECWSU1_RS07250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECWSU1_RS07255	COG4988	ABC transporter
ECWSU1_RS07260	COG0492	ferredoxin-NADP+ reductase activity
ECWSU1_RS07275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ECWSU1_RS07280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECWSU1_RS07285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ECWSU1_RS07290	COG0243	molybdopterin cofactor binding
ECWSU1_RS07295	COG0437	4 iron, 4 sulfur cluster binding
ECWSU1_RS07300	COG3302	dmso reductase anchor subunit
ECWSU1_RS07305	COG0477	Major facilitator Superfamily
ECWSU1_RS07315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECWSU1_RS07330	COG1944	ATP diphosphatase activity
ECWSU1_RS07335	COG2323	membrane
ECWSU1_RS07340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ECWSU1_RS07345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ECWSU1_RS07350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ECWSU1_RS07355	COG0539	negative regulation of cytoplasmic translation
ECWSU1_RS07360	COG0776	regulation of translation
ECWSU1_RS07365	COG0658	competence protein
ECWSU1_RS07365	COG2333	competence protein COMEC
ECWSU1_RS07370	COG1132	(ABC) transporter
ECWSU1_RS07375	COG1663	tetraacyldisaccharide 4'-kinase activity
ECWSU1_RS07380	COG3214	Protein conserved in bacteria
ECWSU1_RS07385	COG2835	tetraacyldisaccharide 4'-kinase activity
ECWSU1_RS07390	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ECWSU1_RS07395	COG3173	Aminoglycoside phosphotransferase
ECWSU1_RS07400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECWSU1_RS07415	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECWSU1_RS07420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ECWSU1_RS07425	COG2989	Protein conserved in bacteria
ECWSU1_RS07430	COG3108	Peptidase M15
ECWSU1_RS07435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECWSU1_RS07440	COG1448	Aminotransferase
ECWSU1_RS07450	COG0017	Asparaginyl-tRNA synthetase
ECWSU1_RS07455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ECWSU1_RS07460	COG0308	aminopeptidase N
ECWSU1_RS07470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECWSU1_RS07475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS07480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECWSU1_RS07485	COG0431	NADPH-dependent FMN reductase
ECWSU1_RS07490	COG0167	dihydroorotate dehydrogenase activity
ECWSU1_RS07500	COG0633	Ferredoxin
ECWSU1_RS07500	COG3217	Mosc domain protein beta barrel domain protein
ECWSU1_RS07505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ECWSU1_RS07505	COG0116	Belongs to the methyltransferase superfamily
ECWSU1_RS07510	COG0488	(ABC) transporter
ECWSU1_RS07515	COG2995	paraquat-inducible protein a
ECWSU1_RS07520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECWSU1_RS07520	COG3008	intermembrane lipid transfer
ECWSU1_RS07525	COG3009	Protein conserved in bacteria
ECWSU1_RS07530	COG3130	regulation of translation
ECWSU1_RS07540	COG1067	ATP-dependent peptidase activity
ECWSU1_RS07545	COG3120	sequence-specific DNA binding
ECWSU1_RS07555	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
ECWSU1_RS07560	COG3070	regulator of competence-specific genes
ECWSU1_RS07565	COG1289	transmembrane transporter activity
ECWSU1_RS07570	COG3304	Inner membrane component domain
ECWSU1_RS07575	COG0210	DNA helicase
ECWSU1_RS07580	COG1803	Methylglyoxal synthase
ECWSU1_RS07585	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ECWSU1_RS07590	COG1832	CoA-binding protein
ECWSU1_RS07600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ECWSU1_RS07605	COG1881	PFAM PEBP family protein
ECWSU1_RS07615	COG1254	Belongs to the acylphosphatase family
ECWSU1_RS07620	COG2920	part of a sulfur-relay system
ECWSU1_RS07625	COG0670	Belongs to the BI1 family
ECWSU1_RS07685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECWSU1_RS07695	COG2351	hydroxyisourate hydrolase activity
ECWSU1_RS07700	COG0402	S-adenosylhomocysteine deaminase activity
ECWSU1_RS07705	COG1953	Uracil, thiamine, allantoin
ECWSU1_RS07760	COG0765	amino acid transport
ECWSU1_RS07770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ECWSU1_RS07785	COG2182	Extracellular solute-binding protein
ECWSU1_RS07790	COG1175	transmembrane transport
ECWSU1_RS07795	COG3833	ABC-type maltose transport systems, permease component
ECWSU1_RS07800	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ECWSU1_RS07805	COG1874	Beta-galactosidase
ECWSU1_RS07810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS07810	COG1263	PTS System
ECWSU1_RS07825	COG2239	Acts as a magnesium transporter
ECWSU1_RS07830	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS07840	COG1733	regulation of RNA biosynthetic process
ECWSU1_RS07860	COG3729	General stress protein
ECWSU1_RS07870	COG2233	PERMEase
ECWSU1_RS07875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECWSU1_RS07880	COG0778	Nitroreductase
ECWSU1_RS07885	COG2267	carboxylic ester hydrolase activity
ECWSU1_RS07890	COG0251	oxidation-reduction process
ECWSU1_RS07895	COG1335	isochorismatase
ECWSU1_RS07900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS07905	COG1309	transcriptional regulator
ECWSU1_RS07915	COG0506	proline dehydrogenase activity
ECWSU1_RS07915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECWSU1_RS07915	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ECWSU1_RS07920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECWSU1_RS07930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECWSU1_RS07940	COG2822	iron ion transport
ECWSU1_RS07955	COG1702	phosphate starvation-inducible protein PhoH
ECWSU1_RS07965	COG1335	isochorismatase
ECWSU1_RS07975	COG0583	DNA-binding transcription factor activity
ECWSU1_RS07985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECWSU1_RS07990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ECWSU1_RS07995	COG3381	protein complex oligomerization
ECWSU1_RS08045	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ECWSU1_RS08060	COG2943	transferase activity, transferring hexosyl groups
ECWSU1_RS08065	COG5645	(Lipo)protein
ECWSU1_RS08080	COG1560	Kdo2-lipid A biosynthetic process
ECWSU1_RS08085	COG1054	Belongs to the UPF0176 family
ECWSU1_RS08090	COG2353	YceI-like domain
ECWSU1_RS08095	COG3038	cytochrome b561
ECWSU1_RS08125	COG0418	dihydroorotase activity
ECWSU1_RS08135	COG0477	Major facilitator Superfamily
ECWSU1_RS08140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECWSU1_RS08145	COG3132	Protein of unknown function, DUF480
ECWSU1_RS08150	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS08180	COG1558	bacterial-type flagellum-dependent cell motility
ECWSU1_RS08190	COG1749	Flagellar hook protein flgE
ECWSU1_RS08195	COG4787	bacterial-type flagellum-dependent cell motility
ECWSU1_RS08200	COG4786	Flagellar basal body rod
ECWSU1_RS08220	COG1256	bacterial-type flagellum assembly
ECWSU1_RS08230	COG2814	Major facilitator Superfamily
ECWSU1_RS08235	COG0583	DNA-binding transcription factor activity
ECWSU1_RS08240	COG1530	ribonuclease E activity
ECWSU1_RS08245	COG0564	pseudouridine synthase activity
ECWSU1_RS08260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ECWSU1_RS08265	COG0416	fatty acid biosynthetic process
ECWSU1_RS08270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECWSU1_RS08285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECWSU1_RS08290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECWSU1_RS08295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECWSU1_RS08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECWSU1_RS08305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECWSU1_RS08310	COG0470	DNA polymerase III
ECWSU1_RS08315	COG0084	hydrolase, TatD family'
ECWSU1_RS08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS08320	COG1263	PTS System
ECWSU1_RS08325	COG4773	Receptor
ECWSU1_RS08330	COG0537	adenosine 5'-monophosphoramidase activity
ECWSU1_RS08335	COG5633	Lipoprotein
ECWSU1_RS08340	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ECWSU1_RS08355	COG3150	esterase
ECWSU1_RS08360	COG1252	NADH dehydrogenase
ECWSU1_RS08365	COG3134	Outer membrane lipoprotein
ECWSU1_RS08370	COG1309	transcriptional regulator
ECWSU1_RS08380	COG1376	ErfK ybiS ycfS ynhG family protein
ECWSU1_RS08380	COG1388	LysM domain
ECWSU1_RS08385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECWSU1_RS08390	COG4763	Acyl-transferase
ECWSU1_RS08395	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECWSU1_RS08400	COG1136	(ABC) transporter
ECWSU1_RS08405	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECWSU1_RS08415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECWSU1_RS08420	COG0840	transmembrane signaling receptor activity
ECWSU1_RS08425	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ECWSU1_RS08460	COG2850	peptidyl-arginine hydroxylation
ECWSU1_RS08475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECWSU1_RS08480	COG2915	High frequency lysogenization protein hflD homolog
ECWSU1_RS08500	COG0538	isocitrate dehydrogenase activity
ECWSU1_RS08505	COG4124	Belongs to the glycosyl hydrolase 26 family
ECWSU1_RS08530	COG2200	EAL domain
ECWSU1_RS08535	COG3706	GGDEF domain
ECWSU1_RS08535	COG2203	Gaf domain
ECWSU1_RS08535	COG5001	Diguanylate cyclase
ECWSU1_RS08535	COG4251	negative regulation of phosphorylation
ECWSU1_RS08540	COG2261	transglycosylase associated protein
ECWSU1_RS08550	COG2203	Gaf domain
ECWSU1_RS08550	COG2199	diguanylate cyclase activity
ECWSU1_RS08555	COG3042	response to heat
ECWSU1_RS08565	COG3189	MarR family transcriptional regulator
ECWSU1_RS08570	COG0504	CTP synthase activity
ECWSU1_RS08575	COG2807	transmembrane transport
ECWSU1_RS08580	COG2207	Transcriptional regulator
ECWSU1_RS08585	COG2707	UPF0756 membrane protein
ECWSU1_RS08590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECWSU1_RS08595	COG2718	Belongs to the UPF0229 family
ECWSU1_RS08600	COG2766	serine protein kinase
ECWSU1_RS08605	COG3713	MltA-interacting MipA family protein
ECWSU1_RS08610	COG0656	L-ascorbic acid biosynthetic process
ECWSU1_RS08630	COG3139	Protein of unknown function (DUF1315)
ECWSU1_RS08640	COG1335	isochorismatase
ECWSU1_RS08645	COG0252	asparaginase activity
ECWSU1_RS08650	COG0616	signal peptide processing
ECWSU1_RS08655	COG0778	Nitroreductase
ECWSU1_RS08660	COG0709	Synthesizes selenophosphate from selenide and ATP
ECWSU1_RS08665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECWSU1_RS08680	COG0494	nUDIX hydrolase
ECWSU1_RS08685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS08690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECWSU1_RS08695	COG2897	thiosulfate sulfurtransferase activity
ECWSU1_RS08700	COG4136	ATPase activity
ECWSU1_RS08705	COG4135	transport system, permease component
ECWSU1_RS08710	COG4134	Bacterial extracellular solute-binding protein
ECWSU1_RS08720	COG0708	Exodeoxyribonuclease III
ECWSU1_RS08730	COG3138	arginine N-succinyltransferase
ECWSU1_RS08735	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS08740	COG3724	N-succinylarginine dihydrolase activity
ECWSU1_RS08750	COG3678	ATP-independent chaperone mediated protein folding
ECWSU1_RS08760	COG0322	excinuclease ABC activity
ECWSU1_RS08765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ECWSU1_RS08770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECWSU1_RS08775	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS08780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS08785	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECWSU1_RS08790	COG2169	Transcriptional regulator
ECWSU1_RS08790	COG1917	Cupin 2, conserved barrel domain protein
ECWSU1_RS08795	COG1486	melibiose metabolic process
ECWSU1_RS08800	COG3394	polysaccharide catabolic process
ECWSU1_RS08805	COG0753	catalase activity
ECWSU1_RS08815	COG1823	symporter activity
ECWSU1_RS08820	COG1988	membrane-bound metal-dependent
ECWSU1_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS08830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECWSU1_RS08840	COG3001	Fructosamine kinase
ECWSU1_RS08850	COG1105	Belongs to the carbohydrate kinase PfkB family
ECWSU1_RS08855	COG3137	Salt-induced outer membrane protein
ECWSU1_RS08875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ECWSU1_RS08885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ECWSU1_RS08895	COG0776	regulation of translation
ECWSU1_RS08905	COG0386	Belongs to the glutathione peroxidase family
ECWSU1_RS08915	COG0791	NLP P60 protein
ECWSU1_RS08925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ECWSU1_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS08935	COG2610	gluconate transmembrane transporter activity
ECWSU1_RS08950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ECWSU1_RS08955	COG0583	DNA-binding transcription factor activity
ECWSU1_RS08965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS08970	COG4558	Periplasmic binding protein
ECWSU1_RS08975	COG3720	iron ion transport
ECWSU1_RS08985	COG4256	Hemin uptake protein
ECWSU1_RS08995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ECWSU1_RS09005	COG2211	Major facilitator Superfamily
ECWSU1_RS09010	COG1472	Belongs to the glycosyl hydrolase 3 family
ECWSU1_RS09015	COG0628	permease
ECWSU1_RS09020	COG0277	FAD linked oxidase domain protein
ECWSU1_RS09020	COG0247	lactate metabolic process
ECWSU1_RS09025	COG2050	protein possibly involved in aromatic compounds catabolism
ECWSU1_RS09035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECWSU1_RS09045	COG3539	Fimbrial protein
ECWSU1_RS09050	COG3121	Chaperone
ECWSU1_RS09080	COG3383	formate dehydrogenase (NAD+) activity
ECWSU1_RS09100	COG2200	EAL domain
ECWSU1_RS09105	COG0789	Transcriptional regulator
ECWSU1_RS09110	COG0316	Belongs to the HesB IscA family
ECWSU1_RS09115	COG0719	Fe-S assembly protein
ECWSU1_RS09120	COG0396	ATPase activity
ECWSU1_RS09125	COG0719	Fe-S assembly protein
ECWSU1_RS09130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECWSU1_RS09135	COG2166	iron-sulfur cluster assembly
ECWSU1_RS09140	COG1376	ErfK ybiS ycfS ynhG family protein
ECWSU1_RS09155	COG0626	cystathionine gamma-synthase activity
ECWSU1_RS09170	COG2011	ABC-type metal ion transport system permease component
ECWSU1_RS09175	COG1464	Belongs to the NlpA lipoprotein family
ECWSU1_RS09185	COG0765	amino acid transport
ECWSU1_RS09190	COG0765	amino acid transport
ECWSU1_RS09200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS09210	COG4191	Histidine kinase
ECWSU1_RS09215	COG4566	intracellular signal transduction
ECWSU1_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECWSU1_RS09240	COG4529	Protein conserved in bacteria
ECWSU1_RS09255	COG0534	Mate efflux family protein
ECWSU1_RS09260	COG0307	riboflavin synthase, alpha
ECWSU1_RS09265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECWSU1_RS09270	COG2814	Major facilitator Superfamily
ECWSU1_RS09275	COG0583	DNA-binding transcription factor activity
ECWSU1_RS09290	COG2814	Major facilitator Superfamily
ECWSU1_RS09300	COG0791	NLP P60 protein
ECWSU1_RS09305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECWSU1_RS09310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECWSU1_RS09315	COG0346	lactoylglutathione lyase activity
ECWSU1_RS09320	COG1902	pentaerythritol trinitrate reductase activity
ECWSU1_RS09325	COG1309	transcriptional regulator
ECWSU1_RS09330	COG2194	sulfuric ester hydrolase activity
ECWSU1_RS09335	COG3313	Fe-S protein
ECWSU1_RS09340	COG4989	oxidoreductase activity
ECWSU1_RS09345	COG2032	superoxide dismutase activity
ECWSU1_RS09355	COG1566	PFAM secretion protein HlyD family protein
ECWSU1_RS09370	COG3706	GGDEF domain
ECWSU1_RS09380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ECWSU1_RS09385	COG3895	Periplasmic Protein
ECWSU1_RS09390	COG0259	pyridoxamine-phosphate oxidase activity
ECWSU1_RS09395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ECWSU1_RS09400	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ECWSU1_RS09405	COG0625	glutathione transferase activity
ECWSU1_RS09410	COG3104	oligopeptide transport
ECWSU1_RS09415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECWSU1_RS09465	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS09470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ECWSU1_RS09475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECWSU1_RS09480	COG1263	PTS System
ECWSU1_RS09480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS09485	COG1609	Transcriptional regulator
ECWSU1_RS09490	COG5339	Protein conserved in bacteria
ECWSU1_RS09495	COG1482	cell wall glycoprotein biosynthetic process
ECWSU1_RS09500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECWSU1_RS09500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECWSU1_RS09515	COG2205	protein histidine kinase activity
ECWSU1_RS09520	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS09525	COG3136	membrane protein required for alginate biosynthesis
ECWSU1_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS09535	COG0531	amino acid
ECWSU1_RS09545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECWSU1_RS09550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECWSU1_RS09575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECWSU1_RS09580	COG1473	amidohydrolase
ECWSU1_RS09590	COG0583	DNA-binding transcription factor activity
ECWSU1_RS09595	COG2840	Smr protein MutS2
ECWSU1_RS09605	COG0667	Aldo Keto reductase
ECWSU1_RS09610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECWSU1_RS09620	COG0583	DNA-binding transcription factor activity
ECWSU1_RS09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECWSU1_RS09635	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECWSU1_RS09645	COG1403	HNH endonuclease
ECWSU1_RS09650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS09655	COG0628	permease
ECWSU1_RS09660	COG2076	Multidrug Resistance protein
ECWSU1_RS09665	COG2076	Multidrug Resistance protein
ECWSU1_RS09670	COG5001	Diguanylate cyclase
ECWSU1_RS09675	COG3591	Belongs to the peptidase S1B family
ECWSU1_RS09695	COG2814	Major facilitator Superfamily
ECWSU1_RS09700	COG0583	DNA-binding transcription factor activity
ECWSU1_RS09705	COG1940	carbohydrate kinase activity
ECWSU1_RS09710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECWSU1_RS09745	COG0625	glutathione transferase activity
ECWSU1_RS09770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECWSU1_RS09770	COG1116	anion transmembrane transporter activity
ECWSU1_RS09775	COG3665	Urea carboxylase-associated protein
ECWSU1_RS09780	COG3665	Urea carboxylase-associated protein
ECWSU1_RS09785	COG0439	Biotin carboxylase
ECWSU1_RS09795	COG3381	protein complex oligomerization
ECWSU1_RS09800	COG3302	dmso reductase anchor subunit
ECWSU1_RS09805	COG0437	4 iron, 4 sulfur cluster binding
ECWSU1_RS09810	COG0243	molybdopterin cofactor binding
ECWSU1_RS09830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECWSU1_RS09840	COG1742	UPF0060 membrane protein
ECWSU1_RS09845	COG4948	Mandelate Racemase Muconate Lactonizing
ECWSU1_RS09850	COG1063	alcohol dehydrogenase
ECWSU1_RS09855	COG0477	Major facilitator Superfamily
ECWSU1_RS09860	COG0246	Mannitol dehydrogenase
ECWSU1_RS09870	COG0589	response to stress
ECWSU1_RS09875	COG1802	Transcriptional regulator
ECWSU1_RS09880	COG4221	oxidoreductase activity
ECWSU1_RS09900	COG3188	usher protein
ECWSU1_RS09920	COG2200	EAL domain
ECWSU1_RS09920	COG2771	luxR family
ECWSU1_RS09965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECWSU1_RS09970	COG2911	Protein conserved in bacteria
ECWSU1_RS09980	COG3784	Protein of unknown function (DUF1318)
ECWSU1_RS09985	COG2207	Transcriptional regulator
ECWSU1_RS09990	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS09995	COG2203	Gaf domain
ECWSU1_RS09995	COG3706	GGDEF domain
ECWSU1_RS09995	COG5001	Diguanylate cyclase
ECWSU1_RS09995	COG4251	negative regulation of phosphorylation
ECWSU1_RS10005	COG2030	dehydratase
ECWSU1_RS10005	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS10010	COG3396	Phenylacetate-CoA oxygenase
ECWSU1_RS10015	COG3460	Phenylacetate-CoA oxygenase
ECWSU1_RS10020	COG3396	Phenylacetate-CoA oxygenase
ECWSU1_RS10025	COG2151	metal-sulfur cluster biosynthetic enzyme
ECWSU1_RS10030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECWSU1_RS10035	COG1024	Enoyl-CoA hydratase
ECWSU1_RS10040	COG1024	Enoyl-CoA hydratase
ECWSU1_RS10045	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECWSU1_RS10050	COG2050	protein possibly involved in aromatic compounds catabolism
ECWSU1_RS10055	COG0183	Belongs to the thiolase family
ECWSU1_RS10060	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ECWSU1_RS10065	COG3327	negative regulation of DNA-templated transcription, initiation
ECWSU1_RS10070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECWSU1_RS10080	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10095	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10115	COG0300	oxidoreductase activity
ECWSU1_RS10120	COG0789	Transcriptional regulator
ECWSU1_RS10125	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10130	COG1902	pentaerythritol trinitrate reductase activity
ECWSU1_RS10170	COG0300	oxidoreductase activity
ECWSU1_RS10185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECWSU1_RS10230	COG3122	Protein conserved in bacteria
ECWSU1_RS10245	COG1643	Atp-dependent helicase
ECWSU1_RS10250	COG4122	O-methyltransferase activity
ECWSU1_RS10255	COG1538	Outer membrane efflux protein
ECWSU1_RS10270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECWSU1_RS10275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECWSU1_RS10280	COG3038	cytochrome b561
ECWSU1_RS10285	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS10290	COG1349	DNA-binding transcription factor activity
ECWSU1_RS10330	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECWSU1_RS10345	COG0840	transmembrane signaling receptor activity
ECWSU1_RS10350	COG4993	Dehydrogenase
ECWSU1_RS10355	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS10365	COG3111	PFAM Bacterial OB fold (BOF) protein
ECWSU1_RS10375	COG2323	membrane
ECWSU1_RS10380	COG1546	Belongs to the CinA family
ECWSU1_RS10395	COG1294	oxidase, subunit
ECWSU1_RS10400	COG1271	oxidase subunit
ECWSU1_RS10405	COG3546	catalase activity
ECWSU1_RS10410	COG3685	Protein conserved in bacteria
ECWSU1_RS10420	COG3685	Protein conserved in bacteria
ECWSU1_RS10425	COG3729	General stress protein
ECWSU1_RS10430	COG5383	Protein conserved in bacteria
ECWSU1_RS10435	COG2272	Belongs to the type-B carboxylesterase lipase family
ECWSU1_RS10445	COG0436	Aminotransferase
ECWSU1_RS10455	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ECWSU1_RS10460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECWSU1_RS10465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECWSU1_RS10470	COG1275	C4-dicarboxylate transporter malic acid transport protein
ECWSU1_RS10475	COG0500	methyltransferase
ECWSU1_RS10480	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECWSU1_RS10485	COG0747	negative chemotaxis
ECWSU1_RS10495	COG0697	spore germination
ECWSU1_RS10505	COG3135	benzoate transporter
ECWSU1_RS10510	COG1396	sequence-specific DNA binding
ECWSU1_RS10515	COG0826	peptidase U32
ECWSU1_RS10540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ECWSU1_RS10560	COG0411	ABC transporter
ECWSU1_RS10570	COG3443	Belongs to the bacterial solute-binding protein 9 family
ECWSU1_RS10575	COG2814	Major facilitator Superfamily
ECWSU1_RS10580	COG0697	spore germination
ECWSU1_RS10595	COG1846	Transcriptional regulator
ECWSU1_RS10605	COG2814	Major facilitator Superfamily
ECWSU1_RS10625	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10635	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS10645	COG0840	transmembrane signaling receptor activity
ECWSU1_RS10650	COG2066	Belongs to the glutaminase family
ECWSU1_RS10660	COG2199	diguanylate cyclase activity
ECWSU1_RS10665	COG3706	GGDEF domain
ECWSU1_RS10675	COG0246	Mannitol dehydrogenase
ECWSU1_RS10680	COG3781	membrane
ECWSU1_RS10690	COG0456	acetyltransferase
ECWSU1_RS10695	COG0596	Alpha beta hydrolase
ECWSU1_RS10715	COG4106	trans-aconitate 2-methyltransferase activity
ECWSU1_RS10720	COG0494	nUDIX hydrolase
ECWSU1_RS10755	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECWSU1_RS10760	COG0667	Aldo Keto reductase
ECWSU1_RS10770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ECWSU1_RS10790	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS10805	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS10820	COG2814	Major facilitator Superfamily
ECWSU1_RS10855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ECWSU1_RS10865	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ECWSU1_RS10880	COG0583	DNA-binding transcription factor activity
ECWSU1_RS10885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECWSU1_RS10890	COG4628	conserved protein (DUF2132)
ECWSU1_RS10895	COG1649	PFAM Uncharacterised BCR, COG1649
ECWSU1_RS10900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECWSU1_RS11075	COG4695	Portal protein
ECWSU1_RS11135	COG4974	Belongs to the 'phage' integrase family
ECWSU1_RS11140	COG0840	transmembrane signaling receptor activity
ECWSU1_RS11170	COG2200	EAL domain
ECWSU1_RS11185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ECWSU1_RS11190	COG0747	negative chemotaxis
ECWSU1_RS11195	COG0601	transmembrane transport
ECWSU1_RS11200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECWSU1_RS11205	COG0444	Belongs to the ABC transporter superfamily
ECWSU1_RS11210	COG4608	Belongs to the ABC transporter superfamily
ECWSU1_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS11235	COG1764	response to oxidative stress
ECWSU1_RS11265	COG0281	malic enzyme
ECWSU1_RS11270	COG0488	(ABC) transporter
ECWSU1_RS11275	COG1064	alcohol dehydrogenase
ECWSU1_RS11285	COG1252	NADH dehydrogenase
ECWSU1_RS11290	COG2814	Major facilitator Superfamily
ECWSU1_RS11295	COG2135	peptidase activity
ECWSU1_RS11355	COG1783	phage Terminase large subunit
ECWSU1_RS11415	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECWSU1_RS11545	COG0582	viral genome integration into host DNA
ECWSU1_RS11555	COG2864	formate dehydrogenase
ECWSU1_RS11560	COG0437	4 iron, 4 sulfur cluster binding
ECWSU1_RS11565	COG0243	molybdopterin cofactor binding
ECWSU1_RS11565	COG3383	formate dehydrogenase (NAD+) activity
ECWSU1_RS11570	COG3383	formate dehydrogenase (NAD+) activity
ECWSU1_RS11570	COG0243	molybdopterin cofactor binding
ECWSU1_RS11600	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS11605	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECWSU1_RS11610	COG1140	nitrate reductase beta subunit
ECWSU1_RS11615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECWSU1_RS11620	COG2181	nitrate reductase activity
ECWSU1_RS11625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ECWSU1_RS11630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ECWSU1_RS11635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECWSU1_RS11640	COG0640	Transcriptional regulator
ECWSU1_RS11645	COG1942	4-Oxalocrotonate Tautomerase
ECWSU1_RS11650	COG0625	glutathione transferase activity
ECWSU1_RS11660	COG1126	abc transporter atp-binding protein
ECWSU1_RS11680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS11685	COG1473	amidohydrolase
ECWSU1_RS11690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS11695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ECWSU1_RS11695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ECWSU1_RS11700	COG0840	transmembrane signaling receptor activity
ECWSU1_RS11715	COG4772	TonB-dependent receptor
ECWSU1_RS11720	COG1802	Transcriptional regulator
ECWSU1_RS11725	COG2130	NADP-dependent
ECWSU1_RS11730	COG1396	sequence-specific DNA binding
ECWSU1_RS11735	COG1247	-acetyltransferase
ECWSU1_RS11740	COG3238	Protein conserved in bacteria
ECWSU1_RS11750	COG0747	negative chemotaxis
ECWSU1_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS11785	COG1177	transmembrane transport
ECWSU1_RS11790	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECWSU1_RS11795	COG3842	ATPase activity
ECWSU1_RS11800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECWSU1_RS11805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECWSU1_RS11815	COG1271	oxidase subunit
ECWSU1_RS11820	COG1294	oxidase, subunit
ECWSU1_RS11830	COG3187	Heat shock protein
ECWSU1_RS11835	COG3042	response to heat
ECWSU1_RS11840	COG1013	pyruvate-flavodoxin oxidoreductase activity
ECWSU1_RS11840	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECWSU1_RS11840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ECWSU1_RS11840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECWSU1_RS11845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECWSU1_RS11875	COG2135	peptidase activity
ECWSU1_RS11915	COG5484	DNA packaging
ECWSU1_RS11915	COG3728	DNA packaging
ECWSU1_RS11935	COG3772	lysozyme
ECWSU1_RS11955	COG0484	heat shock protein binding
ECWSU1_RS11960	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ECWSU1_RS11975	COG3459	Glycosyltransferase 36 associated
ECWSU1_RS11990	COG1846	Transcriptional regulator
ECWSU1_RS12040	COG0582	viral genome integration into host DNA
ECWSU1_RS12050	COG0513	Belongs to the DEAD box helicase family
ECWSU1_RS12060	COG0840	transmembrane signaling receptor activity
ECWSU1_RS12070	COG3706	GGDEF domain
ECWSU1_RS12080	COG0693	protein deglycase activity
ECWSU1_RS12090	COG4166	transmembrane transport
ECWSU1_RS12095	COG2866	Carboxypeptidase
ECWSU1_RS12100	COG4948	Mandelate Racemase Muconate Lactonizing
ECWSU1_RS12105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECWSU1_RS12120	COG3768	UPF0283 membrane protein
ECWSU1_RS12125	COG3106	COG3106 Predicted ATPase
ECWSU1_RS12130	COG1609	Transcriptional regulator
ECWSU1_RS12140	COG3842	ATPase activity
ECWSU1_RS12145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECWSU1_RS12150	COG1554	hydrolase, family 65, central catalytic
ECWSU1_RS12155	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS12160	COG1082	Xylose isomerase domain protein TIM barrel
ECWSU1_RS12165	COG1063	alcohol dehydrogenase
ECWSU1_RS12170	COG0395	ABC-type sugar transport system, permease component
ECWSU1_RS12175	COG1175	transmembrane transport
ECWSU1_RS12180	COG1653	transport
ECWSU1_RS12185	COG0366	Alpha amylase catalytic
ECWSU1_RS12195	COG1983	PspC domain protein
ECWSU1_RS12205	COG1842	Phage shock protein A
ECWSU1_RS12210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECWSU1_RS12225	COG4171	peptide transport system, permease
ECWSU1_RS12235	COG4172	Belongs to the ABC transporter superfamily
ECWSU1_RS12245	COG0251	oxidation-reduction process
ECWSU1_RS12250	COG3708	Transcriptional regulator
ECWSU1_RS12250	COG2207	Transcriptional regulator
ECWSU1_RS12255	COG3706	GGDEF domain
ECWSU1_RS12265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECWSU1_RS12270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS12270	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS12275	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ECWSU1_RS12280	COG5001	Diguanylate cyclase
ECWSU1_RS12285	COG1024	Enoyl-CoA hydratase
ECWSU1_RS12295	COG1349	DNA-binding transcription factor activity
ECWSU1_RS12305	COG0023	Translation Initiation Factor
ECWSU1_RS12310	COG0284	orotidine-5'-phosphate decarboxylase activity
ECWSU1_RS12315	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECWSU1_RS12320	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECWSU1_RS12325	COG0671	phosphoesterase, PA-phosphatase related
ECWSU1_RS12335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ECWSU1_RS12370	COG0616	signal peptide processing
ECWSU1_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS12380	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECWSU1_RS12390	COG0009	L-threonylcarbamoyladenylate synthase
ECWSU1_RS12395	COG0613	PHP domain protein
ECWSU1_RS12405	COG0512	Glutamine amidotransferase of anthranilate synthase
ECWSU1_RS12405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECWSU1_RS12420	COG0159	tryptophan synthase activity
ECWSU1_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS12445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS12485	COG0656	L-ascorbic acid biosynthetic process
ECWSU1_RS12490	COG0668	transmembrane transport
ECWSU1_RS12495	COG1278	Cold shock
ECWSU1_RS12515	COG1846	Transcriptional regulator
ECWSU1_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS12560	COG5002	protein histidine kinase activity
ECWSU1_RS12565	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS12575	COG1917	Cupin 2, conserved barrel domain protein
ECWSU1_RS12575	COG4977	sequence-specific DNA binding
ECWSU1_RS12580	COG4221	oxidoreductase activity
ECWSU1_RS12585	COG4221	oxidoreductase activity
ECWSU1_RS12595	COG0583	DNA-binding transcription factor activity
ECWSU1_RS12600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECWSU1_RS12605	COG0604	alcohol dehydrogenase
ECWSU1_RS12630	COG2391	methyltransferase activity
ECWSU1_RS12635	COG0425	Belongs to the sulfur carrier protein TusA family
ECWSU1_RS12655	COG3047	cAMP biosynthetic process
ECWSU1_RS12660	COG0727	PFAM Uncharacterised protein family (UPF0153)
ECWSU1_RS12685	COG2350	Protein conserved in bacteria
ECWSU1_RS12690	COG1280	lysine exporter protein (LysE YggA)
ECWSU1_RS12705	COG3099	Belongs to the UPF0263 family
ECWSU1_RS12710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECWSU1_RS12715	COG4608	Belongs to the ABC transporter superfamily
ECWSU1_RS12720	COG0444	Belongs to the ABC transporter superfamily
ECWSU1_RS12730	COG0601	transmembrane transport
ECWSU1_RS12745	COG2095	MarC family integral membrane protein
ECWSU1_RS12750	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS12750	COG1454	alcohol dehydrogenase
ECWSU1_RS12755	COG1435	thymidine kinase activity
ECWSU1_RS12765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ECWSU1_RS12770	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS12775	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECWSU1_RS12780	COG3012	SEC-C Motif Domain Protein
ECWSU1_RS12785	COG0788	formyltetrahydrofolate deformylase activity
ECWSU1_RS12800	COG1522	sequence-specific DNA binding
ECWSU1_RS12805	COG0697	spore germination
ECWSU1_RS12850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECWSU1_RS12855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECWSU1_RS12860	COG2181	nitrate reductase activity
ECWSU1_RS12865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ECWSU1_RS12870	COG1140	nitrate reductase beta subunit
ECWSU1_RS12875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ECWSU1_RS12880	COG2223	nitrite transmembrane transporter activity
ECWSU1_RS12885	COG3850	Histidine kinase
ECWSU1_RS12890	COG2197	response regulator
ECWSU1_RS12895	COG4932	domain protein
ECWSU1_RS12900	COG0243	molybdopterin cofactor binding
ECWSU1_RS12905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECWSU1_RS12905	COG2146	nitrite reductase [NAD(P)H] activity
ECWSU1_RS12910	COG1116	anion transmembrane transporter activity
ECWSU1_RS12920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECWSU1_RS12925	COG3707	response regulator
ECWSU1_RS12930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECWSU1_RS12935	COG0840	transmembrane signaling receptor activity
ECWSU1_RS12945	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ECWSU1_RS12950	COG4572	Cation transport regulator
ECWSU1_RS12955	COG0387	Pfam Sodium calcium exchanger
ECWSU1_RS12975	COG2890	protein-(glutamine-N5) methyltransferase activity
ECWSU1_RS12985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ECWSU1_RS12990	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ECWSU1_RS12995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ECWSU1_RS13005	COG0659	secondary active sulfate transmembrane transporter activity
ECWSU1_RS13020	COG0193	aminoacyl-tRNA hydrolase activity
ECWSU1_RS13025	COG0012	GTP binding
ECWSU1_RS13185	COG3209	COG3209 Rhs family protein
ECWSU1_RS13225	COG1397	ADP-ribosylglycohydrolase
ECWSU1_RS13230	COG4104	PAAR repeat-containing protein
ECWSU1_RS13260	COG0515	serine threonine protein kinase
ECWSU1_RS13380	COG0243	molybdopterin cofactor binding
ECWSU1_RS13385	COG0583	DNA-binding transcription factor activity
ECWSU1_RS13400	COG4977	sequence-specific DNA binding
ECWSU1_RS13410	COG2814	Major facilitator Superfamily
ECWSU1_RS13425	COG4774	siderophore transport
ECWSU1_RS13440	COG0741	lytic transglycosylase activity
ECWSU1_RS13445	COG1619	proteins homologs of microcin C7 resistance protein MccF
ECWSU1_RS13450	COG3263	regulation of cellular component size
ECWSU1_RS13455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECWSU1_RS13460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECWSU1_RS13470	COG2719	SpoVR family
ECWSU1_RS13475	COG2186	Transcriptional regulator
ECWSU1_RS13490	COG2983	Belongs to the UPF0260 family
ECWSU1_RS13495	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECWSU1_RS13500	COG3100	YcgL domain-containing protein
ECWSU1_RS13505	COG0850	regulation of cytokinetic process
ECWSU1_RS13510	COG2894	cell division
ECWSU1_RS13515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ECWSU1_RS13520	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECWSU1_RS13530	COG3065	identical protein binding
ECWSU1_RS13535	COG1214	PFAM Peptidase M22, glycoprotease
ECWSU1_RS13540	COG1199	ATP-dependent helicase activity
ECWSU1_RS13545	COG0251	oxidation-reduction process
ECWSU1_RS13555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECWSU1_RS13560	COG0494	nUDIX hydrolase
ECWSU1_RS13565	COG1760	l-serine dehydratase
ECWSU1_RS13570	COG2200	EAL domain
ECWSU1_RS13575	COG1253	flavin adenine dinucleotide binding
ECWSU1_RS13580	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS13580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS13585	COG3715	PTS system
ECWSU1_RS13590	COG3716	PTS system mannose fructose sorbose family IID component
ECWSU1_RS13595	COG4811	Protein of unknown function (DUF986)
ECWSU1_RS13600	COG1971	Probably functions as a manganese efflux pump
ECWSU1_RS13605	COG2226	methyltransferase
ECWSU1_RS13610	COG0768	penicillin binding
ECWSU1_RS13645	COG1414	Transcriptional regulator
ECWSU1_RS13650	COG2814	Major facilitator Superfamily
ECWSU1_RS13655	COG0501	Belongs to the peptidase M48B family
ECWSU1_RS13670	COG1956	GAF domain-containing protein
ECWSU1_RS13675	COG2995	paraquat-inducible protein a
ECWSU1_RS13680	COG3008	intermembrane lipid transfer
ECWSU1_RS13685	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ECWSU1_RS13685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ECWSU1_RS13700	COG2990	Protein conserved in bacteria
ECWSU1_RS13720	COG1276	copper resistance
ECWSU1_RS13725	COG2372	response to copper ion
ECWSU1_RS13735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECWSU1_RS13740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECWSU1_RS13745	COG1770	oligopeptidase
ECWSU1_RS13750	COG2979	Protein of unknown function (DUF533)
ECWSU1_RS13760	COG0800	Aldolase
ECWSU1_RS13765	COG0129	dihydroxy-acid dehydratase activity
ECWSU1_RS13770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECWSU1_RS13775	COG1737	Transcriptional regulator
ECWSU1_RS13785	COG1560	Kdo2-lipid A biosynthetic process
ECWSU1_RS13790	COG0739	heme binding
ECWSU1_RS13795	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECWSU1_RS13805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECWSU1_RS13810	COG2255	four-way junction helicase activity
ECWSU1_RS13815	COG0632	four-way junction helicase activity
ECWSU1_RS13830	COG0494	nUDIX hydrolase
ECWSU1_RS13840	COG1335	isochorismatase
ECWSU1_RS13845	COG1801	Protein of unknown function DUF72
ECWSU1_RS13850	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECWSU1_RS13855	COG2226	methyltransferase
ECWSU1_RS13860	COG0500	methyltransferase
ECWSU1_RS13865	COG3142	Participates in the control of copper homeostasis
ECWSU1_RS13870	COG3102	Protein conserved in bacteria
ECWSU1_RS13875	COG0018	arginyl-trna synthetase
ECWSU1_RS13880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ECWSU1_RS13910	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS13925	COG0840	transmembrane signaling receptor activity
ECWSU1_RS13960	COG1301	dicarboxylic acid transport
ECWSU1_RS14000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ECWSU1_RS14010	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS14020	COG1879	ABC-type sugar transport system periplasmic component
ECWSU1_RS14030	COG1528	Iron-storage protein
ECWSU1_RS14035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECWSU1_RS14050	COG0784	Response regulator, receiver
ECWSU1_RS14050	COG3437	response regulator, receiver
ECWSU1_RS14060	COG1528	Iron-storage protein
ECWSU1_RS14070	COG0814	amino acid
ECWSU1_RS14075	COG3318	Belongs to the UPF0149 family
ECWSU1_RS14075	COG3012	SEC-C Motif Domain Protein
ECWSU1_RS14110	COG1278	Cold shock
ECWSU1_RS14125	COG1349	DNA-binding transcription factor activity
ECWSU1_RS14130	COG1454	alcohol dehydrogenase
ECWSU1_RS14160	COG2197	response regulator
ECWSU1_RS14170	COG2197	response regulator
ECWSU1_RS14175	COG1126	abc transporter atp-binding protein
ECWSU1_RS14180	COG0765	amino acid transport
ECWSU1_RS14190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS14255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECWSU1_RS14270	COG0366	Alpha amylase catalytic
ECWSU1_RS14280	COG1677	Flagellar hook-basal body complex protein FliE
ECWSU1_RS14290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECWSU1_RS14300	COG1157	protein secretion by the type III secretion system
ECWSU1_RS14340	COG1987	bacterial-type flagellum assembly
ECWSU1_RS14350	COG2197	response regulator
ECWSU1_RS14375	COG5475	Uncharacterized small protein (DUF2158)
ECWSU1_RS14380	COG2354	Protein conserved in bacteria
ECWSU1_RS14385	COG0697	spore germination
ECWSU1_RS14390	COG3727	T/G mismatch-specific endonuclease activity
ECWSU1_RS14395	COG0270	DNA (cytosine-5-)-methyltransferase activity
ECWSU1_RS14400	COG1418	mRNA catabolic process
ECWSU1_RS14415	COG3290	protein histidine kinase activity
ECWSU1_RS14420	COG4565	transcriptional regulatory protein
ECWSU1_RS14440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ECWSU1_RS14440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ECWSU1_RS14465	COG0583	DNA-binding transcription factor activity
ECWSU1_RS14535	COG1376	ErfK ybiS ycfS ynhG family protein
ECWSU1_RS14540	COG0477	Major facilitator Superfamily
ECWSU1_RS14545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECWSU1_RS14560	COG0534	Mate efflux family protein
ECWSU1_RS14580	COG1289	transmembrane transporter activity
ECWSU1_RS14585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ECWSU1_RS14595	COG2925	Exonuclease
ECWSU1_RS14600	COG0531	amino acid
ECWSU1_RS14605	COG0583	DNA-binding transcription factor activity
ECWSU1_RS14610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECWSU1_RS14615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ECWSU1_RS14625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ECWSU1_RS14630	COG0131	Imidazoleglycerol-phosphate dehydratase
ECWSU1_RS14630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECWSU1_RS14635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECWSU1_RS14640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ECWSU1_RS14645	COG0107	imidazoleglycerol-phosphate synthase activity
ECWSU1_RS14675	COG1215	transferase activity, transferring glycosyl groups
ECWSU1_RS14685	COG0438	transferase activity, transferring glycosyl groups
ECWSU1_RS14710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ECWSU1_RS14715	COG1091	dTDP-4-dehydrorhamnose reductase activity
ECWSU1_RS14735	COG0438	transferase activity, transferring glycosyl groups
ECWSU1_RS14740	COG2327	Polysaccharide pyruvyl transferase
ECWSU1_RS14745	COG2244	polysaccharide biosynthetic process
ECWSU1_RS14750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ECWSU1_RS14755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECWSU1_RS14765	COG0297	glycogen (starch) synthase activity
ECWSU1_RS14770	COG1051	belongs to the nudix hydrolase family
ECWSU1_RS14775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECWSU1_RS14780	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECWSU1_RS14785	COG0110	maltose O-acetyltransferase activity
ECWSU1_RS14790	COG1216	Glycosyl transferase, family 2
ECWSU1_RS14800	COG0438	transferase activity, transferring glycosyl groups
ECWSU1_RS14805	COG1045	serine acetyltransferase
ECWSU1_RS14810	COG0463	Glycosyl transferase, family 2
ECWSU1_RS14815	COG3206	protein involved in exopolysaccharide biosynthesis
ECWSU1_RS14815	COG0489	protein tyrosine kinase activity
ECWSU1_RS14830	COG1253	flavin adenine dinucleotide binding
ECWSU1_RS14835	COG2982	Protein involved in outer membrane biogenesis
ECWSU1_RS14840	COG0717	Belongs to the dCTP deaminase family
ECWSU1_RS14850	COG5002	protein histidine kinase activity
ECWSU1_RS14850	COG5001	Diguanylate cyclase
ECWSU1_RS14850	COG3447	MASE1 domain protein
ECWSU1_RS14855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECWSU1_RS14860	COG0443	Heat shock 70 kDa protein
ECWSU1_RS14865	COG2200	EAL domain
ECWSU1_RS14865	COG2771	luxR family
ECWSU1_RS14905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS14910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECWSU1_RS14915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECWSU1_RS14920	COG0477	Major facilitator Superfamily
ECWSU1_RS14925	COG2205	protein histidine kinase activity
ECWSU1_RS14930	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS14935	COG3422	double-strand break repair
ECWSU1_RS14940	COG0826	peptidase U32
ECWSU1_RS14945	COG1597	lipid kinase activity
ECWSU1_RS14950	COG1830	Aldolase
ECWSU1_RS14955	COG2211	Major facilitator Superfamily
ECWSU1_RS14960	COG1397	ADP-ribosylglycohydrolase
ECWSU1_RS14965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECWSU1_RS14970	COG2188	Transcriptional regulator
ECWSU1_RS14975	COG0351	phosphomethylpyrimidine kinase
ECWSU1_RS14980	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ECWSU1_RS14985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECWSU1_RS14990	COG0076	glutamate decarboxylase activity
ECWSU1_RS14995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECWSU1_RS15000	COG0583	DNA-binding transcription factor activity
ECWSU1_RS15010	COG2252	PERMEase
ECWSU1_RS15015	COG0489	protein tyrosine kinase activity
ECWSU1_RS15015	COG3206	protein involved in exopolysaccharide biosynthesis
ECWSU1_RS15020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECWSU1_RS15025	COG1596	polysaccharide export
ECWSU1_RS15030	COG5455	response to cobalt ion
ECWSU1_RS15040	COG0489	protein tyrosine kinase activity
ECWSU1_RS15050	COG4807	Protein conserved in bacteria
ECWSU1_RS15060	COG3275	phosphorelay sensor kinase activity
ECWSU1_RS15065	COG0789	Transcriptional regulator
ECWSU1_RS15070	COG1174	glycine betaine transport
ECWSU1_RS15075	COG1125	glycine betaine transport
ECWSU1_RS15080	COG1174	glycine betaine transport
ECWSU1_RS15085	COG1732	Glycine betaine
ECWSU1_RS15090	COG1472	Belongs to the glycosyl hydrolase 3 family
ECWSU1_RS15095	COG0277	FAD linked oxidase domain protein
ECWSU1_RS15105	COG1686	Belongs to the peptidase S11 family
ECWSU1_RS15115	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS15125	COG1538	Outer membrane efflux protein
ECWSU1_RS15130	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS15145	COG3659	wide pore channel activity
ECWSU1_RS15150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECWSU1_RS15160	COG1346	cytolysis
ECWSU1_RS15165	COG0295	cytidine deaminase activity
ECWSU1_RS15170	COG2949	membrane
ECWSU1_RS15175	COG0174	glutamine synthetase
ECWSU1_RS15185	COG1129	ABC transporter
ECWSU1_RS15200	COG2311	Membrane
ECWSU1_RS15205	COG0302	gtp cyclohydrolase
ECWSU1_RS15210	COG0477	Major facilitator Superfamily
ECWSU1_RS15215	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ECWSU1_RS15220	COG4771	TonB-dependent receptor
ECWSU1_RS15225	COG0833	amino acid
ECWSU1_RS15230	COG0583	DNA-binding transcription factor activity
ECWSU1_RS15235	COG2855	membrane
ECWSU1_RS15240	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ECWSU1_RS15245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS15245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECWSU1_RS15245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECWSU1_RS15250	COG1105	Belongs to the carbohydrate kinase PfkB family
ECWSU1_RS15275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ECWSU1_RS15280	COG1312	Catalyzes the dehydration of D-mannonate
ECWSU1_RS15285	COG0246	Mannitol dehydrogenase
ECWSU1_RS15290	COG0523	cobalamin synthesis protein
ECWSU1_RS15295	COG0671	phosphoesterase, PA-phosphatase related
ECWSU1_RS15300	COG0791	NLP P60 protein
ECWSU1_RS15305	COG2200	EAL domain
ECWSU1_RS15310	COG4166	transmembrane transport
ECWSU1_RS15315	COG4174	ABC transporter (Permease)
ECWSU1_RS15320	COG4239	(ABC) transporter, permease
ECWSU1_RS15325	COG4172	Belongs to the ABC transporter superfamily
ECWSU1_RS15335	COG2814	Major facilitator Superfamily
ECWSU1_RS15340	COG1187	pseudouridine synthase activity
ECWSU1_RS15345	COG1061	Type III restriction enzyme res subunit
ECWSU1_RS15355	COG3081	Nucleoid-associated protein
ECWSU1_RS15360	COG3082	Protein of unknown function (DUF1414)
ECWSU1_RS15400	COG3182	Iron-regulated membrane protein
ECWSU1_RS15410	COG0579	oxidoreductase
ECWSU1_RS15415	COG0659	secondary active sulfate transmembrane transporter activity
ECWSU1_RS15420	COG2239	Acts as a magnesium transporter
ECWSU1_RS15425	COG4615	Cyclic peptide transporter
ECWSU1_RS15430	COG3145	DNA-N1-methyladenine dioxygenase activity
ECWSU1_RS15435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECWSU1_RS15435	COG2169	Transcriptional regulator
ECWSU1_RS15450	COG2198	Histidine kinase
ECWSU1_RS15450	COG0642	Histidine kinase
ECWSU1_RS15455	COG2197	response regulator
ECWSU1_RS15460	COG0784	Response regulator, receiver
ECWSU1_RS15460	COG2205	protein histidine kinase activity
ECWSU1_RS15470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECWSU1_RS15475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECWSU1_RS15480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECWSU1_RS15485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECWSU1_RS15490	COG0584	glycerophosphoryl diester phosphodiesterase
ECWSU1_RS15495	COG2271	Major facilitator Superfamily
ECWSU1_RS15500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECWSU1_RS15505	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ECWSU1_RS15510	COG0247	lactate metabolic process
ECWSU1_RS15555	COG1441	menaquinone biosynthetic process
ECWSU1_RS15565	COG0596	Alpha beta hydrolase
ECWSU1_RS15570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ECWSU1_RS15575	COG1169	isochorismate synthase
ECWSU1_RS15580	COG4575	ribosome binding
ECWSU1_RS15585	COG2153	protein acetylation
ECWSU1_RS15590	COG1234	tRNA 3'-trailer cleavage
ECWSU1_RS15595	COG0784	Response regulator, receiver
ECWSU1_RS15595	COG0835	chemotaxis
ECWSU1_RS15600	COG1007	ATP synthesis coupled electron transport
ECWSU1_RS15605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECWSU1_RS15610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECWSU1_RS15615	COG0713	ATP synthesis coupled electron transport
ECWSU1_RS15620	COG0839	Belongs to the complex I subunit 6 family
ECWSU1_RS15630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ECWSU1_RS15660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECWSU1_RS15665	COG0583	DNA-binding transcription factor activity
ECWSU1_RS15670	COG0436	Aminotransferase
ECWSU1_RS15680	COG0471	metal ion transport
ECWSU1_RS15680	COG0490	domain, Protein
ECWSU1_RS15685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECWSU1_RS15710	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ECWSU1_RS15715	COG3959	Transketolase, thiamine diphosphate binding domain
ECWSU1_RS15720	COG3037	sugar-specific permease SgaT UlaA
ECWSU1_RS15730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS15735	COG1609	Transcriptional regulator
ECWSU1_RS15745	COG0622	Phosphoesterase
ECWSU1_RS15750	COG0625	glutathione transferase activity
ECWSU1_RS15755	COG0625	glutathione transferase activity
ECWSU1_RS15760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECWSU1_RS15765	COG1090	epimerase
ECWSU1_RS15775	COG4598	ABC transporter
ECWSU1_RS15780	COG4160	amino acid transport
ECWSU1_RS15790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS15800	COG0163	prenyltransferase activity
ECWSU1_RS15805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECWSU1_RS15810	COG1286	toxin biosynthetic process
ECWSU1_RS15815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECWSU1_RS15820	COG0285	dihydrofolate synthase activity
ECWSU1_RS15830	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS15835	COG0101	tRNA pseudouridine synthase activity
ECWSU1_RS15840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECWSU1_RS15845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECWSU1_RS15860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECWSU1_RS15865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECWSU1_RS15865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ECWSU1_RS15875	COG3101	peptidyl-lysine hydroxylation
ECWSU1_RS15880	COG0730	response to heat
ECWSU1_RS15890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ECWSU1_RS15900	COG2840	Smr protein MutS2
ECWSU1_RS15905	COG2062	phosphohistidine phosphatase, SixA
ECWSU1_RS15910	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECWSU1_RS15910	COG1024	Enoyl-CoA hydratase
ECWSU1_RS15920	COG3691	Protein conserved in bacteria
ECWSU1_RS15925	COG2067	long-chain fatty acid transport protein
ECWSU1_RS15935	COG2116	formate transmembrane transporter activity
ECWSU1_RS15950	COG1560	Kdo2-lipid A biosynthetic process
ECWSU1_RS15955	COG0436	Aminotransferase
ECWSU1_RS15960	COG3275	phosphorelay sensor kinase activity
ECWSU1_RS15965	COG3279	Response regulator of the LytR AlgR family
ECWSU1_RS15970	COG0837	glucose binding
ECWSU1_RS15980	COG3961	Belongs to the TPP enzyme family
ECWSU1_RS15985	COG0667	Aldo Keto reductase
ECWSU1_RS15995	COG1914	H( )-stimulated, divalent metal cation uptake system
ECWSU1_RS16000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECWSU1_RS16005	COG2200	EAL domain
ECWSU1_RS16005	COG2199	diguanylate cyclase activity
ECWSU1_RS16020	COG3415	Transposase
ECWSU1_RS16025	COG3415	Transposase
ECWSU1_RS16030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECWSU1_RS16055	COG0583	DNA-binding transcription factor activity
ECWSU1_RS16060	COG2211	Major facilitator Superfamily
ECWSU1_RS16065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ECWSU1_RS16075	COG0583	DNA-binding transcription factor activity
ECWSU1_RS16080	COG0385	Bile acid
ECWSU1_RS16085	COG3530	Putative quorum-sensing-regulated virulence factor
ECWSU1_RS16090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ECWSU1_RS16095	COG3115	cell septum assembly
ECWSU1_RS16110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS16135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ECWSU1_RS16140	COG4208	sulfate ABC transporter
ECWSU1_RS16145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECWSU1_RS16150	COG4150	thiosulfate binding
ECWSU1_RS16155	COG2837	iron assimilation
ECWSU1_RS16175	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECWSU1_RS16180	COG0408	coproporphyrinogen oxidase activity
ECWSU1_RS16195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECWSU1_RS16200	COG5342	invasion associated locus B
ECWSU1_RS16205	COG0494	nUDIX hydrolase
ECWSU1_RS16210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECWSU1_RS16210	COG0493	'glutamate synthase
ECWSU1_RS16215	COG3850	Histidine kinase
ECWSU1_RS16220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECWSU1_RS16225	COG1393	Belongs to the ArsC family
ECWSU1_RS16230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECWSU1_RS16240	COG0400	carboxylic ester hydrolase activity
ECWSU1_RS16245	COG1444	tRNA N-acetyltransferase activity
ECWSU1_RS16250	COG2321	neutral zinc metallopeptidase
ECWSU1_RS16260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ECWSU1_RS16270	COG2716	regulation of RNA biosynthetic process
ECWSU1_RS16275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECWSU1_RS16280	COG0628	permease
ECWSU1_RS16285	COG4783	chaperone-mediated protein folding
ECWSU1_RS16290	COG1393	Belongs to the ArsC family
ECWSU1_RS16305	COG1446	asparaginase
ECWSU1_RS16320	COG2233	PERMEase
ECWSU1_RS16325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ECWSU1_RS16330	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS16340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECWSU1_RS16355	COG2200	EAL domain
ECWSU1_RS16390	COG2814	Major facilitator Superfamily
ECWSU1_RS16395	COG3718	enzyme involved in inositol metabolism
ECWSU1_RS16410	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS16415	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS16425	COG1879	ABC-type sugar transport system periplasmic component
ECWSU1_RS16430	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS16435	COG3962	Belongs to the TPP enzyme family
ECWSU1_RS16455	COG0517	IMP dehydrogenase activity
ECWSU1_RS16455	COG0516	GMP reductase activity
ECWSU1_RS16460	COG1570	exodeoxyribonuclease VII activity
ECWSU1_RS16475	COG1645	bacterial-type flagellum-dependent swarming motility
ECWSU1_RS16490	COG1160	GTP binding
ECWSU1_RS16500	COG2976	Protein conserved in bacteria
ECWSU1_RS16505	COG0124	histidyl-tRNA synthetase
ECWSU1_RS16510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ECWSU1_RS16520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ECWSU1_RS16530	COG4953	penicillin-binding protein 1C
ECWSU1_RS16535	COG2373	Large extracellular alpha-helical protein
ECWSU1_RS16540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS16540	COG1263	PTS System
ECWSU1_RS16540	COG2190	(PTS) system
ECWSU1_RS16550	COG2897	thiosulfate sulfurtransferase activity
ECWSU1_RS16555	COG1737	Transcriptional regulator
ECWSU1_RS16565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ECWSU1_RS16570	COG2975	iron-sulfur cluster assembly
ECWSU1_RS16575	COG0633	Ferredoxin
ECWSU1_RS16580	COG0443	Heat shock 70 kDa protein
ECWSU1_RS16590	COG0316	Belongs to the HesB IscA family
ECWSU1_RS16595	COG0822	iron-sulfur transferase activity
ECWSU1_RS16600	COG1104	cysteine desulfurase activity
ECWSU1_RS16620	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ECWSU1_RS16630	COG3711	transcriptional antiterminator
ECWSU1_RS16635	COG2814	Major facilitator Superfamily
ECWSU1_RS16640	COG2259	Doxx family
ECWSU1_RS16645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ECWSU1_RS16650	COG1017	nitric oxide dioxygenase activity
ECWSU1_RS16650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECWSU1_RS16655	COG0347	Belongs to the P(II) protein family
ECWSU1_RS16660	COG2204	response regulator
ECWSU1_RS16665	COG3170	Tfp pilus assembly protein FimV
ECWSU1_RS16670	COG2205	protein histidine kinase activity
ECWSU1_RS16675	COG0047	phosphoribosylformylglycinamidine synthase activity
ECWSU1_RS16675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECWSU1_RS16680	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ECWSU1_RS16690	COG0560	Phosphoserine phosphatase
ECWSU1_RS16695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS16695	COG1263	PTS System
ECWSU1_RS16700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ECWSU1_RS16705	COG1737	Transcriptional regulator
ECWSU1_RS16710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECWSU1_RS16720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ECWSU1_RS16725	COG1381	Involved in DNA repair and RecF pathway recombination
ECWSU1_RS16730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ECWSU1_RS16740	COG0681	Belongs to the peptidase S26 family
ECWSU1_RS16745	COG0481	GTPase activity
ECWSU1_RS16750	COG3086	response to oxidative stress
ECWSU1_RS16760	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ECWSU1_RS16770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECWSU1_RS16775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ECWSU1_RS16780	COG0513	Belongs to the DEAD box helicase family
ECWSU1_RS16785	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ECWSU1_RS16795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECWSU1_RS16800	COG3118	belongs to the thioredoxin family
ECWSU1_RS16805	COG3148	PFAM DTW domain containing protein
ECWSU1_RS16815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECWSU1_RS16820	COG5544	Lipoprotein
ECWSU1_RS16825	COG0477	Major facilitator Superfamily
ECWSU1_RS16850	COG0542	response to heat
ECWSU1_RS16865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECWSU1_RS16870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECWSU1_RS16875	COG0077	Prephenate dehydratase
ECWSU1_RS16875	COG1605	Chorismate mutase
ECWSU1_RS16885	COG1605	Chorismate mutase
ECWSU1_RS16885	COG0287	Prephenate dehydrogenase
ECWSU1_RS16905	COG2199	diguanylate cyclase activity
ECWSU1_RS16910	COG2885	chlorophyll binding
ECWSU1_RS16930	COG0336	Belongs to the RNA methyltransferase TrmD family
ECWSU1_RS16935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ECWSU1_RS16945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECWSU1_RS16950	COG4137	Cytochrome C assembly protein
ECWSU1_RS16955	COG4536	flavin adenine dinucleotide binding
ECWSU1_RS16960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ECWSU1_RS16970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ECWSU1_RS16975	COG0497	DNA recombination
ECWSU1_RS16990	COG2867	negative regulation of translational initiation
ECWSU1_RS17000	COG0582	viral genome integration into host DNA
ECWSU1_RS17010	COG1475	DNA binding
ECWSU1_RS17175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS17180	COG1051	belongs to the nudix hydrolase family
ECWSU1_RS17185	COG2207	Transcriptional regulator
ECWSU1_RS17200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECWSU1_RS17215	COG2226	methyltransferase
ECWSU1_RS17220	COG3958	Transketolase
ECWSU1_RS17225	COG3959	Transketolase, thiamine diphosphate binding domain
ECWSU1_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS17235	COG2271	Major facilitator Superfamily
ECWSU1_RS17240	COG0583	DNA-binding transcription factor activity
ECWSU1_RS17245	COG0402	S-adenosylhomocysteine deaminase activity
ECWSU1_RS17250	COG0549	Belongs to the carbamate kinase family
ECWSU1_RS17260	COG1304	FMN binding
ECWSU1_RS17265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ECWSU1_RS17270	COG0666	response to abiotic stimulus
ECWSU1_RS17275	COG0583	DNA-binding transcription factor activity
ECWSU1_RS17280	COG0401	homolog of Blt101
ECWSU1_RS17285	COG0640	Transcriptional regulator
ECWSU1_RS17290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECWSU1_RS17315	COG4575	ribosome binding
ECWSU1_RS17325	COG1780	Probably involved in ribonucleotide reductase function
ECWSU1_RS17345	COG4176	ABC-type proline glycine betaine transport system permease component
ECWSU1_RS17355	COG2814	Major facilitator Superfamily
ECWSU1_RS17360	COG1846	Transcriptional regulator
ECWSU1_RS17365	COG1566	PFAM secretion protein HlyD family protein
ECWSU1_RS17370	COG2814	Major facilitator Superfamily
ECWSU1_RS17375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ECWSU1_RS17390	COG2918	glutathione biosynthetic process
ECWSU1_RS17395	COG1238	metal cluster binding
ECWSU1_RS17400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECWSU1_RS17430	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ECWSU1_RS17435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ECWSU1_RS17450	COG1546	Belongs to the CinA family
ECWSU1_RS17455	COG0803	Belongs to the bacterial solute-binding protein 9 family
ECWSU1_RS17460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECWSU1_RS17470	COG2951	lytic endotransglycosylase activity
ECWSU1_RS17475	COG3730	PTS system glucitol sorbitol-specific
ECWSU1_RS17480	COG3732	PTS system glucitol sorbitol-specific
ECWSU1_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS17495	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS17500	COG1349	DNA-binding transcription factor activity
ECWSU1_RS17510	COG3604	Transcriptional regulator
ECWSU1_RS17515	COG1773	rubredoxin
ECWSU1_RS17515	COG0426	domain, Protein
ECWSU1_RS17520	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECWSU1_RS17525	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ECWSU1_RS17530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ECWSU1_RS17535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECWSU1_RS17540	COG1609	Transcriptional regulator
ECWSU1_RS17545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS17545	COG1263	PTS System
ECWSU1_RS17550	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS17555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ECWSU1_RS17565	COG3260	NADH ubiquinone oxidoreductase 20
ECWSU1_RS17570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ECWSU1_RS17575	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ECWSU1_RS17575	COG3261	NADH dehydrogenase
ECWSU1_RS17580	COG0650	Formate hydrogenlyase subunit 4
ECWSU1_RS17585	COG0651	ATP synthesis coupled electron transport
ECWSU1_RS17590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECWSU1_RS17605	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECWSU1_RS17610	COG0298	carbon dioxide binding
ECWSU1_RS17615	COG0409	Hydrogenase expression formation protein
ECWSU1_RS17620	COG0309	Hydrogenase expression formation protein (HypE)
ECWSU1_RS17640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ECWSU1_RS17650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECWSU1_RS17655	COG0163	prenyltransferase activity
ECWSU1_RS17670	COG0477	Major facilitator Superfamily
ECWSU1_RS17700	COG0585	pseudouridine synthase activity
ECWSU1_RS17710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ECWSU1_RS17715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ECWSU1_RS17725	COG0529	Catalyzes the synthesis of activated sulfate
ECWSU1_RS17745	COG2234	aminopeptidase activity
ECWSU1_RS17755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECWSU1_RS17760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ECWSU1_RS17765	COG0720	synthase
ECWSU1_RS17770	COG0602	queuosine metabolic process
ECWSU1_RS17775	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ECWSU1_RS17780	COG2190	(PTS) system
ECWSU1_RS17780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS17780	COG1263	PTS System
ECWSU1_RS17785	COG1737	Transcriptional regulator
ECWSU1_RS17805	COG3956	TIGRFAM MazG family protein
ECWSU1_RS17810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECWSU1_RS17815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECWSU1_RS17820	COG3437	response regulator, receiver
ECWSU1_RS17820	COG4999	Histidine kinase
ECWSU1_RS17820	COG2205	protein histidine kinase activity
ECWSU1_RS17820	COG3850	Histidine kinase
ECWSU1_RS17825	COG1929	Belongs to the glycerate kinase type-1 family
ECWSU1_RS17830	COG4948	Mandelate Racemase Muconate Lactonizing
ECWSU1_RS17835	COG4948	Mandelate Racemase Muconate Lactonizing
ECWSU1_RS17840	COG2271	Major facilitator Superfamily
ECWSU1_RS17845	COG0716	FMN binding
ECWSU1_RS17850	COG0564	pseudouridine synthase activity
ECWSU1_RS17855	COG3098	single-species biofilm formation
ECWSU1_RS17870	COG1611	Belongs to the LOG family
ECWSU1_RS17875	COG0814	amino acid
ECWSU1_RS17880	COG1760	l-serine dehydratase
ECWSU1_RS17895	COG2363	Small membrane protein
ECWSU1_RS17900	COG0583	DNA-binding transcription factor activity
ECWSU1_RS17910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECWSU1_RS17915	COG2166	iron-sulfur cluster assembly
ECWSU1_RS17920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECWSU1_RS17925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECWSU1_RS17940	COG0860	N-Acetylmuramoyl-L-alanine amidase
ECWSU1_RS17945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ECWSU1_RS17945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECWSU1_RS17950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECWSU1_RS17955	COG1074	ATP-dependent DNA helicase activity
ECWSU1_RS17965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECWSU1_RS17970	COG4967	type IV pilus modification protein PilV
ECWSU1_RS17985	COG2165	general secretion pathway protein
ECWSU1_RS17990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ECWSU1_RS17995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ECWSU1_RS18005	COG0494	nUDIX hydrolase
ECWSU1_RS18010	COG3066	DNA modification
ECWSU1_RS18020	COG0667	Aldo Keto reductase
ECWSU1_RS18025	COG0477	Major facilitator Superfamily
ECWSU1_RS18030	COG0204	Acyl-transferase
ECWSU1_RS18030	COG0318	PFAM AMP-dependent synthetase and ligase
ECWSU1_RS18040	COG1609	Transcriptional regulator
ECWSU1_RS18050	COG2186	Transcriptional regulator
ECWSU1_RS18055	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS18060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS18065	COG1609	Transcriptional regulator
ECWSU1_RS18075	COG0583	DNA-binding transcription factor activity
ECWSU1_RS18080	COG1794	racemase activity, acting on amino acids and derivatives
ECWSU1_RS18090	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ECWSU1_RS18095	COG1175	transmembrane transport
ECWSU1_RS18100	COG0395	ABC-type sugar transport system, permease component
ECWSU1_RS18105	COG3842	ATPase activity
ECWSU1_RS18115	COG2814	Major facilitator Superfamily
ECWSU1_RS18120	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS18130	COG0823	Involved in the tonB-independent uptake of proteins
ECWSU1_RS18145	COG0183	Belongs to the thiolase family
ECWSU1_RS18160	COG0814	amino acid
ECWSU1_RS18175	COG2388	GCN5-related N-acetyl-transferase
ECWSU1_RS18180	COG3592	Divergent 4Fe-4S mono-cluster
ECWSU1_RS18200	COG4208	sulfate ABC transporter
ECWSU1_RS18205	COG3842	ATPase activity
ECWSU1_RS18215	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS18225	COG4580	involved in the transport of maltose and maltodextrins
ECWSU1_RS18230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS18235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS18240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECWSU1_RS18245	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECWSU1_RS18250	COG1940	carbohydrate kinase activity
ECWSU1_RS18255	COG1609	Transcriptional regulator
ECWSU1_RS18285	COG4942	peptidase
ECWSU1_RS18290	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECWSU1_RS18295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECWSU1_RS18310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECWSU1_RS18320	COG4974	Belongs to the 'phage' integrase family
ECWSU1_RS18335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECWSU1_RS18345	COG1272	protein, Hemolysin III
ECWSU1_RS18350	COG1737	Transcriptional regulator
ECWSU1_RS18355	COG2723	6-phospho-beta-galactosidase activity
ECWSU1_RS18360	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS18365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ECWSU1_RS18365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ECWSU1_RS18375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ECWSU1_RS18380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECWSU1_RS18385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECWSU1_RS18390	COG0006	proline dipeptidase activity
ECWSU1_RS18400	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ECWSU1_RS18410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECWSU1_RS18415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECWSU1_RS18425	COG0583	DNA-binding transcription factor activity
ECWSU1_RS18430	COG2968	Membrane
ECWSU1_RS18435	COG1279	arginine transmembrane transporter activity
ECWSU1_RS18440	COG0668	transmembrane transport
ECWSU1_RS18445	COG0191	fructose-bisphosphate aldolase activity
ECWSU1_RS18455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECWSU1_RS18460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECWSU1_RS18465	COG0501	Belongs to the peptidase M48B family
ECWSU1_RS18485	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ECWSU1_RS18490	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS18495	COG2267	carboxylic ester hydrolase activity
ECWSU1_RS18505	COG2814	Major facilitator Superfamily
ECWSU1_RS18520	COG1414	Transcriptional regulator
ECWSU1_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS18540	COG2146	nitrite reductase [NAD(P)H] activity
ECWSU1_RS18550	COG0010	Belongs to the arginase family
ECWSU1_RS18555	COG1166	arginine decarboxylase activity
ECWSU1_RS18565	COG2814	Major facilitator Superfamily
ECWSU1_RS18570	COG3091	SprT-like family
ECWSU1_RS18575	COG2356	endonuclease I
ECWSU1_RS18580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECWSU1_RS18600	COG2805	Type II/IV secretion system protein
ECWSU1_RS18605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECWSU1_RS18610	COG0762	integral membrane protein
ECWSU1_RS18615	COG1872	DUF167
ECWSU1_RS18625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECWSU1_RS18630	COG2852	Protein conserved in bacteria
ECWSU1_RS18640	COG3171	Protein conserved in bacteria
ECWSU1_RS18650	COG1194	a g-specific adenine glycosylase
ECWSU1_RS18660	COG0741	lytic transglycosylase activity
ECWSU1_RS18665	COG2211	Major facilitator Superfamily
ECWSU1_RS18670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ECWSU1_RS18690	COG3052	prosthetic group binding
ECWSU1_RS18700	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECWSU1_RS18705	COG3493	citrate carrier protein
ECWSU1_RS18720	COG1982	Orn Lys Arg decarboxylase major
ECWSU1_RS18725	COG1811	Na channel or pump
ECWSU1_RS18740	COG0457	Tetratricopeptide repeat
ECWSU1_RS18745	COG1649	PFAM Uncharacterised BCR, COG1649
ECWSU1_RS18745	COG0726	polysaccharide deacetylase
ECWSU1_RS18750	COG1215	transferase activity, transferring glycosyl groups
ECWSU1_RS18760	COG0754	glutathionylspermidine amidase activity
ECWSU1_RS18765	COG0625	glutathione transferase activity
ECWSU1_RS18775	COG0840	transmembrane signaling receptor activity
ECWSU1_RS18780	COG0667	Aldo Keto reductase
ECWSU1_RS18785	COG2862	Uncharacterized protein family, UPF0114
ECWSU1_RS18805	COG0848	biopolymer transport protein
ECWSU1_RS18815	COG0626	cystathionine gamma-synthase activity
ECWSU1_RS18820	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS18825	COG2207	Transcriptional regulator
ECWSU1_RS18830	COG1979	alcohol dehydrogenase
ECWSU1_RS18840	COG1032	radical SAM domain protein
ECWSU1_RS18845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECWSU1_RS18865	COG3111	PFAM Bacterial OB fold (BOF) protein
ECWSU1_RS18880	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECWSU1_RS18885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECWSU1_RS18890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ECWSU1_RS18895	COG2211	Major facilitator Superfamily
ECWSU1_RS18905	COG2207	Transcriptional regulator
ECWSU1_RS18905	COG1917	Cupin 2, conserved barrel domain protein
ECWSU1_RS18920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS18925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECWSU1_RS18930	COG1120	ATPase activity
ECWSU1_RS18935	COG4774	siderophore transport
ECWSU1_RS18940	COG0187	DNA topoisomerase II activity
ECWSU1_RS18945	COG3150	esterase
ECWSU1_RS18950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECWSU1_RS18955	COG3151	Protein conserved in bacteria
ECWSU1_RS18960	COG0494	nUDIX hydrolase
ECWSU1_RS18975	COG0754	glutathionylspermidine amidase activity
ECWSU1_RS18980	COG3384	dioxygenase
ECWSU1_RS18990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ECWSU1_RS19000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ECWSU1_RS19000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ECWSU1_RS19010	COG3025	triphosphatase activity
ECWSU1_RS19015	COG4991	sh3 domain protein
ECWSU1_RS19020	COG0617	tRNA 3'-terminal CCA addition
ECWSU1_RS19030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECWSU1_RS19040	COG0477	Major facilitator Superfamily
ECWSU1_RS19045	COG0829	nickel cation binding
ECWSU1_RS19050	COG0831	urea catabolic process
ECWSU1_RS19055	COG0832	Belongs to the urease beta subunit family
ECWSU1_RS19060	COG0804	urea catabolic process
ECWSU1_RS19065	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ECWSU1_RS19075	COG0830	nickel cation binding
ECWSU1_RS19080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECWSU1_RS19090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECWSU1_RS19095	COG0358	DNA primase activity
ECWSU1_RS19120	COG3663	DNA glycosylase
ECWSU1_RS19265	COG2375	cellular response to nickel ion
ECWSU1_RS19270	COG1695	Transcriptional regulator
ECWSU1_RS19275	COG0840	transmembrane signaling receptor activity
ECWSU1_RS19280	COG0840	transmembrane signaling receptor activity
ECWSU1_RS19285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECWSU1_RS19300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECWSU1_RS19305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ECWSU1_RS19310	COG1830	Aldolase
ECWSU1_RS19315	COG1879	ABC-type sugar transport system periplasmic component
ECWSU1_RS19320	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS19325	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS19330	COG1129	ABC transporter
ECWSU1_RS19335	COG2390	Transcriptional regulator
ECWSU1_RS19340	COG1070	Carbohydrate kinase
ECWSU1_RS19345	COG1902	pentaerythritol trinitrate reductase activity
ECWSU1_RS19345	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECWSU1_RS19355	COG1451	nucleotide metabolic process
ECWSU1_RS19360	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS19365	COG0861	Integral membrane protein TerC family
ECWSU1_RS19375	COG2721	sulfolactate sulfo-lyase activity
ECWSU1_RS19385	COG2271	Major facilitator Superfamily
ECWSU1_RS19390	COG2186	Transcriptional regulator
ECWSU1_RS19395	COG0586	Pfam SNARE associated Golgi protein
ECWSU1_RS19405	COG1422	Protein of unknown function (DUF1090)
ECWSU1_RS19410	COG4575	ribosome binding
ECWSU1_RS19415	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ECWSU1_RS19425	COG2259	Doxx family
ECWSU1_RS19430	COG0435	Glutathione S-transferase
ECWSU1_RS19435	COG3152	Membrane
ECWSU1_RS19440	COG0583	DNA-binding transcription factor activity
ECWSU1_RS19445	COG1741	Belongs to the pirin family
ECWSU1_RS19455	COG0814	amino acid
ECWSU1_RS19465	COG1882	Formate acetyltransferase
ECWSU1_RS19470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECWSU1_RS19475	COG0814	amino acid
ECWSU1_RS19480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECWSU1_RS19485	COG0583	DNA-binding transcription factor activity
ECWSU1_RS19490	COG1929	Belongs to the glycerate kinase type-1 family
ECWSU1_RS19495	COG2084	Dehydrogenase
ECWSU1_RS19505	COG2721	sulfolactate sulfo-lyase activity
ECWSU1_RS19510	COG1349	DNA-binding transcription factor activity
ECWSU1_RS19520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS19530	COG3716	PTS system mannose fructose sorbose family IID component
ECWSU1_RS19535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS19540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECWSU1_RS19545	COG2222	sugar isomerase
ECWSU1_RS19550	COG0191	fructose-bisphosphate aldolase activity
ECWSU1_RS19555	COG1263	PTS System
ECWSU1_RS19555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECWSU1_RS19560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECWSU1_RS19570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECWSU1_RS19575	COG3107	peptidoglycan biosynthetic process
ECWSU1_RS19580	COG0792	nuclease activity
ECWSU1_RS19585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ECWSU1_RS19590	COG2823	Periplasmic or secreted lipoprotein
ECWSU1_RS19595	COG0701	Predicted permease
ECWSU1_RS19600	COG0702	epimerase
ECWSU1_RS19605	COG0693	protein deglycase activity
ECWSU1_RS19610	COG3787	Belongs to the UPF0306 family
ECWSU1_RS19615	COG2827	Endonuclease containing a URI domain
ECWSU1_RS19620	COG3153	acetyltransferase
ECWSU1_RS19625	COG3154	lipid carrier protein
ECWSU1_RS19630	COG0826	peptidase U32
ECWSU1_RS19635	COG0826	peptidase U32
ECWSU1_RS19640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ECWSU1_RS19645	COG0814	amino acid
ECWSU1_RS19650	COG0513	Belongs to the DEAD box helicase family
ECWSU1_RS19660	COG1185	polyribonucleotide nucleotidyltransferase activity
ECWSU1_RS19665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ECWSU1_RS19670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ECWSU1_RS19675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ECWSU1_RS19680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ECWSU1_RS19700	COG0137	argininosuccinate synthase activity
ECWSU1_RS19710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECWSU1_RS19715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECWSU1_RS19720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECWSU1_RS19730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ECWSU1_RS19735	COG1534	Rna-binding protein
ECWSU1_RS19745	COG2027	D-alanyl-D-alanine carboxypeptidase
ECWSU1_RS19750	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS19755	COG0642	Histidine kinase
ECWSU1_RS19760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ECWSU1_RS19765	COG0697	spore germination
ECWSU1_RS19775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ECWSU1_RS19780	COG0142	geranyltranstransferase activity
ECWSU1_RS19785	COG3423	Transcriptional regulator
ECWSU1_RS19790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ECWSU1_RS19795	COG5007	Belongs to the BolA IbaG family
ECWSU1_RS19800	COG3113	response to antibiotic
ECWSU1_RS19805	COG2854	intermembrane phospholipid transfer
ECWSU1_RS19810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECWSU1_RS19815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECWSU1_RS19820	COG1127	ABC transporter
ECWSU1_RS19825	COG0530	calcium, potassium:sodium antiporter activity
ECWSU1_RS19835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECWSU1_RS19840	COG3117	lipopolysaccharide transmembrane transporter activity
ECWSU1_RS19845	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECWSU1_RS19850	COG1137	ATPase activity
ECWSU1_RS19855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ECWSU1_RS19875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS19885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECWSU1_RS19890	COG5002	protein histidine kinase activity
ECWSU1_RS19890	COG2198	Histidine kinase
ECWSU1_RS19890	COG0784	Response regulator, receiver
ECWSU1_RS19895	COG0795	lipopolysaccharide-transporting ATPase activity
ECWSU1_RS19900	COG0795	lipopolysaccharide-transporting ATPase activity
ECWSU1_RS19905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ECWSU1_RS19910	COG2927	DNA polymerase III (CHI subunit)
ECWSU1_RS19925	COG1064	alcohol dehydrogenase
ECWSU1_RS19935	COG0433	COG0433 Predicted ATPase
ECWSU1_RS19940	COG1242	4 iron, 4 sulfur cluster binding
ECWSU1_RS19945	COG0067	glutamate synthase
ECWSU1_RS19945	COG0069	glutamate synthase activity
ECWSU1_RS19945	COG0070	glutamate synthase
ECWSU1_RS19950	COG0493	'glutamate synthase
ECWSU1_RS19960	COG3188	usher protein
ECWSU1_RS19965	COG3121	Chaperone
ECWSU1_RS19970	COG3539	Fimbrial protein
ECWSU1_RS19975	COG2969	positive regulation of protein catabolic process
ECWSU1_RS19980	COG0625	glutathione transferase activity
ECWSU1_RS19985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ECWSU1_RS19995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECWSU1_RS20000	COG3105	Protein conserved in bacteria
ECWSU1_RS20005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECWSU1_RS20010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECWSU1_RS20015	COG0039	L-malate dehydrogenase activity
ECWSU1_RS20035	COG2732	(Barnase) inhibitor
ECWSU1_RS20040	COG1012	belongs to the aldehyde dehydrogenase family
ECWSU1_RS20045	COG1289	transmembrane transporter activity
ECWSU1_RS20060	COG0583	DNA-binding transcription factor activity
ECWSU1_RS20065	COG3477	response to acidic pH
ECWSU1_RS20070	COG0312	modulator of DNA gyrase
ECWSU1_RS20075	COG3164	Protein of unknown function
ECWSU1_RS20090	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECWSU1_RS20095	COG1792	Involved in formation and maintenance of cell shape
ECWSU1_RS20100	COG1077	Cell shape determining protein MreB Mrl
ECWSU1_RS20105	COG2200	EAL domain
ECWSU1_RS20105	COG2199	diguanylate cyclase activity
ECWSU1_RS20110	COG0604	alcohol dehydrogenase
ECWSU1_RS20120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ECWSU1_RS20125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ECWSU1_RS20130	COG0511	ligase activity, forming carbon-carbon bonds
ECWSU1_RS20135	COG0439	Biotin carboxylase
ECWSU1_RS20140	COG3924	membrane
ECWSU1_RS20145	COG4145	pantothenate transmembrane transporter activity
ECWSU1_RS20180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS20185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECWSU1_RS20195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECWSU1_RS20200	COG4597	amino acid ABC transporter
ECWSU1_RS20205	COG0765	amino acid transport
ECWSU1_RS20210	COG1126	abc transporter atp-binding protein
ECWSU1_RS20245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECWSU1_RS20255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ECWSU1_RS20260	COG0009	L-threonylcarbamoyladenylate synthase
ECWSU1_RS20265	COG0551	DNA topoisomerase type I activity
ECWSU1_RS20270	COG2922	Belongs to the Smg family
ECWSU1_RS20275	COG0758	DNA mediated transformation
ECWSU1_RS20280	COG0242	peptide deformylase activity
ECWSU1_RS20285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ECWSU1_RS20290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ECWSU1_RS20290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ECWSU1_RS20305	COG3036	rescue of stalled ribosome
ECWSU1_RS20310	COG0789	Transcriptional regulator
ECWSU1_RS20320	COG0203	ribosomal protein L17
ECWSU1_RS20325	COG0202	RNA polymerase activity
ECWSU1_RS20335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ECWSU1_RS20350	COG0201	protein transport
ECWSU1_RS20360	COG1841	ribosomal large subunit assembly
ECWSU1_RS20370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ECWSU1_RS20375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ECWSU1_RS20380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ECWSU1_RS20410	COG0255	Belongs to the universal ribosomal protein uL29 family
ECWSU1_RS20415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ECWSU1_RS20455	COG0051	transcription antitermination factor activity, RNA binding
ECWSU1_RS20495	COG2168	tRNA wobble position uridine thiolation
ECWSU1_RS20500	COG2923	Belongs to the DsrF TusC family
ECWSU1_RS20505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECWSU1_RS20510	COG2964	Protein conserved in bacteria
ECWSU1_RS20515	COG0545	Peptidyl-prolyl cis-trans isomerase
ECWSU1_RS20520	COG2900	Belongs to the SlyX family
ECWSU1_RS20525	COG1047	Peptidyl-prolyl cis-trans
ECWSU1_RS20530	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ECWSU1_RS20535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECWSU1_RS20535	COG0475	glutathione-regulated potassium exporter activity
ECWSU1_RS20540	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECWSU1_RS20545	COG0488	(ABC) transporter
ECWSU1_RS20555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ECWSU1_RS20565	COG0679	Auxin Efflux Carrier
ECWSU1_RS20600	COG0429	hydrolase of the alpha beta-hydrolase fold
ECWSU1_RS20605	COG3089	Belongs to the UPF0270 family
ECWSU1_RS20610	COG3954	Phosphoribulokinase
ECWSU1_RS20615	COG1765	OsmC-like protein
ECWSU1_RS20625	COG1289	transmembrane transporter activity
ECWSU1_RS20635	COG0512	Glutamine amidotransferase of anthranilate synthase
ECWSU1_RS20650	COG0738	Major facilitator superfamily
ECWSU1_RS20655	COG0402	S-adenosylhomocysteine deaminase activity
ECWSU1_RS20660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECWSU1_RS20670	COG1648	precorrin-2 dehydrogenase activity
ECWSU1_RS20670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ECWSU1_RS20680	COG0180	Tryptophanyl-tRNA synthetase
ECWSU1_RS20690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECWSU1_RS20695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECWSU1_RS20700	COG3266	domain, Protein
ECWSU1_RS20705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ECWSU1_RS20710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ECWSU1_RS20715	COG4796	Type ii and iii secretion system protein
ECWSU1_RS20740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECWSU1_RS20745	COG0494	nUDIX hydrolase
ECWSU1_RS20755	COG1011	Hydrolase
ECWSU1_RS20760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECWSU1_RS20765	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ECWSU1_RS20770	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ECWSU1_RS20785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECWSU1_RS20790	COG2183	response to ionizing radiation
ECWSU1_RS20795	COG1918	ferrous iron import across plasma membrane
ECWSU1_RS20820	COG1040	competence protein
ECWSU1_RS20830	COG2610	gluconate transmembrane transporter activity
ECWSU1_RS20835	COG1640	4-alpha-glucanotransferase
ECWSU1_RS20840	COG0058	SHG alpha-glucan phosphorylase activity
ECWSU1_RS20845	COG2909	trisaccharide binding
ECWSU1_RS20850	COG1349	DNA-binding transcription factor activity
ECWSU1_RS20855	COG0705	Rhomboid family
ECWSU1_RS20860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECWSU1_RS20870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECWSU1_RS20875	COG0058	SHG alpha-glucan phosphorylase activity
ECWSU1_RS20880	COG0297	glycogen (starch) synthase activity
ECWSU1_RS20885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ECWSU1_RS20890	COG1523	belongs to the glycosyl hydrolase 13 family
ECWSU1_RS20895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ECWSU1_RS20900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECWSU1_RS20910	COG2095	MarC family integral membrane protein
ECWSU1_RS20915	COG2610	gluconate transmembrane transporter activity
ECWSU1_RS20920	COG3265	gluconokinase activity
ECWSU1_RS20925	COG1609	Transcriptional regulator
ECWSU1_RS20930	COG1741	Belongs to the pirin family
ECWSU1_RS20935	COG0673	inositol 2-dehydrogenase activity
ECWSU1_RS20940	COG1247	-acetyltransferase
ECWSU1_RS20945	COG0405	Gamma-glutamyltransferase
ECWSU1_RS20955	COG0584	glycerophosphoryl diester phosphodiesterase
ECWSU1_RS20985	COG0411	ABC transporter
ECWSU1_RS20990	COG4177	L-phenylalanine transmembrane transporter activity
ECWSU1_RS21000	COG0683	leucine binding
ECWSU1_RS21020	COG0683	leucine binding
ECWSU1_RS21025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECWSU1_RS21030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECWSU1_RS21040	COG2177	Part of the ABC transporter FtsEX involved in
ECWSU1_RS21045	COG2884	Cell division ATP-binding protein ftsE
ECWSU1_RS21050	COG0552	protein localization to endoplasmic reticulum
ECWSU1_RS21055	COG0742	ribosomal rna small subunit methyltransferase
ECWSU1_RS21060	COG3776	membrane
ECWSU1_RS21070	COG3714	YhhN family
ECWSU1_RS21075	COG2217	Heavy metal translocating P-type atpase
ECWSU1_RS21090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECWSU1_RS21095	COG0425	Belongs to the sulfur carrier protein TusA family
ECWSU1_RS21100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECWSU1_RS21110	COG0477	Major facilitator Superfamily
ECWSU1_RS21115	COG0628	permease
ECWSU1_RS21145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECWSU1_RS21155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ECWSU1_RS21155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ECWSU1_RS21165	COG1216	Glycosyl transferase, family 2
ECWSU1_RS21190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECWSU1_RS21200	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS21205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECWSU1_RS21210	COG2091	lysine biosynthetic process via aminoadipic acid
ECWSU1_RS21250	COG3479	Phenolic acid decarboxylase
ECWSU1_RS21255	COG0583	DNA-binding transcription factor activity
ECWSU1_RS21260	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS21265	COG0791	NLP P60 protein
ECWSU1_RS21290	COG1414	Transcriptional regulator
ECWSU1_RS21295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ECWSU1_RS21300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECWSU1_RS21305	COG2081	HI0933 family
ECWSU1_RS21310	COG0306	phosphate transporter
ECWSU1_RS21320	COG0589	response to stress
ECWSU1_RS21330	COG0339	signal peptide processing
ECWSU1_RS21335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECWSU1_RS21340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECWSU1_RS21355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECWSU1_RS21365	COG2197	response regulator
ECWSU1_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS21375	COG0583	DNA-binding transcription factor activity
ECWSU1_RS21380	COG1295	ribonuclease BN
ECWSU1_RS21385	COG0477	Major facilitator Superfamily
ECWSU1_RS21390	COG2982	Protein involved in outer membrane biogenesis
ECWSU1_RS21395	COG2200	EAL domain
ECWSU1_RS21405	COG0612	Peptidase, M16
ECWSU1_RS21410	COG1301	dicarboxylic acid transport
ECWSU1_RS21415	COG2199	diguanylate cyclase activity
ECWSU1_RS21415	COG2200	EAL domain
ECWSU1_RS21420	COG0457	Tetratricopeptide repeat
ECWSU1_RS21420	COG3118	belongs to the thioredoxin family
ECWSU1_RS21425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ECWSU1_RS21430	COG1215	transferase activity, transferring glycosyl groups
ECWSU1_RS21460	COG2194	sulfuric ester hydrolase activity
ECWSU1_RS21475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ECWSU1_RS21505	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ECWSU1_RS21515	COG1739	Uncharacterized protein family UPF0029
ECWSU1_RS21520	COG0006	proline dipeptidase activity
ECWSU1_RS21525	COG1024	Enoyl-CoA hydratase
ECWSU1_RS21525	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECWSU1_RS21530	COG0183	Belongs to the thiolase family
ECWSU1_RS21540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECWSU1_RS21550	COG0084	hydrolase, TatD family'
ECWSU1_RS21555	COG0805	protein transport
ECWSU1_RS21565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECWSU1_RS21570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ECWSU1_RS21575	COG3165	ubiquinone biosynthetic process from chorismate
ECWSU1_RS21580	COG2226	methyltransferase
ECWSU1_RS21585	COG1322	Protein conserved in bacteria
ECWSU1_RS21595	COG0412	Dienelactone hydrolase
ECWSU1_RS21605	COG0583	DNA-binding transcription factor activity
ECWSU1_RS21610	COG0697	spore germination
ECWSU1_RS21615	COG0561	phosphatase activity
ECWSU1_RS21620	COG2267	carboxylic ester hydrolase activity
ECWSU1_RS21625	COG1280	lysine exporter protein (LysE YggA)
ECWSU1_RS21630	COG1280	lysine exporter protein (LysE YggA)
ECWSU1_RS21640	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ECWSU1_RS21665	COG1011	Hydrolase
ECWSU1_RS21700	COG0181	hydroxymethylbilane synthase activity
ECWSU1_RS21710	COG2959	enzyme of heme biosynthesis
ECWSU1_RS21715	COG3071	HemY protein
ECWSU1_RS21750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ECWSU1_RS21765	COG2244	polysaccharide biosynthetic process
ECWSU1_RS21770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECWSU1_RS21775	COG0456	acetyltransferase
ECWSU1_RS21780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ECWSU1_RS21785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECWSU1_RS21795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECWSU1_RS21800	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECWSU1_RS21805	COG3118	belongs to the thioredoxin family
ECWSU1_RS21815	COG0248	Ppx GppA phosphatase
ECWSU1_RS21825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECWSU1_RS21835	COG0583	DNA-binding transcription factor activity
ECWSU1_RS21840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECWSU1_RS21850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECWSU1_RS21855	COG3978	acetolactate synthase activity
ECWSU1_RS21870	COG3085	chromosome segregation
ECWSU1_RS21920	COG4206	TonB-dependent receptor
ECWSU1_RS21925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECWSU1_RS21945	COG0583	DNA-binding transcription factor activity
ECWSU1_RS21950	COG0165	Argininosuccinate lyase
ECWSU1_RS21960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECWSU1_RS21965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECWSU1_RS21970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ECWSU1_RS21975	COG2207	Transcriptional regulator
ECWSU1_RS21985	COG0371	Dehydrogenase
ECWSU1_RS21990	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ECWSU1_RS22000	COG0460	homoserine dehydrogenase
ECWSU1_RS22000	COG0527	aspartate kinase activity
ECWSU1_RS22005	COG0626	cystathionine gamma-synthase activity
ECWSU1_RS22015	COG0254	rRNA binding
ECWSU1_RS22020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECWSU1_RS22025	COG1609	Transcriptional regulator
ECWSU1_RS22030	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECWSU1_RS22045	COG1575	Belongs to the MenA family. Type 1 subfamily
ECWSU1_RS22055	COG3074	FtsZ-dependent cytokinesis
ECWSU1_RS22065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ECWSU1_RS22070	COG1494	fructose-1,6-bisphosphatase
ECWSU1_RS22080	COG3152	Membrane
ECWSU1_RS22090	COG0149	triose-phosphate isomerase activity
ECWSU1_RS22100	COG2134	cdp-diacylglycerol pyrophosphatase
ECWSU1_RS22110	COG0205	6-phosphofructokinase activity
ECWSU1_RS22120	COG3678	ATP-independent chaperone mediated protein folding
ECWSU1_RS22125	COG0745	RESPONSE REGULATOR receiver
ECWSU1_RS22130	COG2205	protein histidine kinase activity
ECWSU1_RS22135	COG2258	MOSC domain
ECWSU1_RS22150	COG1917	Cupin 2, conserved barrel domain protein
ECWSU1_RS22150	COG4977	sequence-specific DNA binding
ECWSU1_RS22155	COG4977	sequence-specific DNA binding
ECWSU1_RS22165	COG1070	Carbohydrate kinase
ECWSU1_RS22170	COG4806	L-rhamnose isomerase
ECWSU1_RS22180	COG3254	rhamnose metabolic process
ECWSU1_RS22185	COG2211	Major facilitator Superfamily
ECWSU1_RS22205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ECWSU1_RS22225	COG3383	formate dehydrogenase (NAD+) activity
ECWSU1_RS22225	COG0243	molybdopterin cofactor binding
ECWSU1_RS22230	COG3383	formate dehydrogenase (NAD+) activity
ECWSU1_RS22230	COG0243	molybdopterin cofactor binding
ECWSU1_RS22235	COG0437	4 iron, 4 sulfur cluster binding
ECWSU1_RS22240	COG2864	formate dehydrogenase
ECWSU1_RS22245	COG3058	Necessary for formate dehydrogenase activity
ECWSU1_RS22255	COG0456	acetyltransferase
ECWSU1_RS22260	COG1490	D-aminoacyl-tRNA deacylase activity
ECWSU1_RS22270	COG1011	Hydrolase
ECWSU1_RS22275	COG1349	DNA-binding transcription factor activity
ECWSU1_RS22280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECWSU1_RS22290	COG3684	Belongs to the aldolase LacD family
ECWSU1_RS22300	COG1501	Belongs to the glycosyl hydrolase 31 family
ECWSU1_RS22315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECWSU1_RS22330	COG3852	Histidine kinase
ECWSU1_RS22345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECWSU1_RS22350	COG3078	GTPase activator activity
ECWSU1_RS22365	COG0204	Acyl-transferase
ECWSU1_RS22375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECWSU1_RS22380	COG3084	Protein conserved in bacteria
ECWSU1_RS22385	COG0746	molybdenum cofactor guanylyltransferase activity
ECWSU1_RS22390	COG1763	Mo-molybdopterin cofactor biosynthetic process
ECWSU1_RS22415	COG2186	Transcriptional regulator
ECWSU1_RS22420	COG0477	Major facilitator Superfamily
ECWSU1_RS22425	COG1609	Transcriptional regulator
ECWSU1_RS22430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECWSU1_RS22440	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECWSU1_RS22445	COG1129	ABC transporter
ECWSU1_RS22450	COG1869	D-ribose catabolic process
ECWSU1_RS22455	COG3158	transport of potassium into the cell
ECWSU1_RS22465	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECWSU1_RS22470	COG2502	aspartate--ammonia ligase
ECWSU1_RS22475	COG1522	sequence-specific DNA binding
ECWSU1_RS22480	COG0716	FMN binding
ECWSU1_RS22485	COG0445	tRNA wobble uridine modification
ECWSU1_RS22490	COG0357	Ribosomal RNA small subunit methyltransferase G
ECWSU1_RS22495	COG3312	ion transport
ECWSU1_RS22500	COG0356	it plays a direct role in the translocation of protons across the membrane
ECWSU1_RS22510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ECWSU1_RS22515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECWSU1_RS22520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ECWSU1_RS22530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ECWSU1_RS22535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ECWSU1_RS22540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECWSU1_RS22550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECWSU1_RS22555	COG0573	inorganic phosphate transmembrane transporter activity
ECWSU1_RS22560	COG0581	inorganic phosphate transmembrane transporter activity
ECWSU1_RS22570	COG0704	Plays a role in the regulation of phosphate uptake
ECWSU1_RS22575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECWSU1_RS22580	COG2252	PERMEase
ECWSU1_RS22585	COG0431	NADPH-dependent FMN reductase
ECWSU1_RS22590	COG2091	lysine biosynthetic process via aminoadipic acid
ECWSU1_RS22605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ECWSU1_RS22610	COG0706	membrane insertase activity
ECWSU1_RS22655	COG4695	Portal protein
ECWSU1_RS22670	COG4974	Belongs to the 'phage' integrase family
ECWSU1_RS22710	COG1192	Involved in chromosome partitioning
ECWSU1_RS22765	COG2963	transposase activity
ECWSU1_RS22775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECWSU1_RS22805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ECWSU1_RS22810	COG0583	DNA-binding transcription factor activity
ECWSU1_RS22815	COG1486	melibiose metabolic process
ECWSU1_RS22825	COG2207	Transcriptional regulator
ECWSU1_RS22830	COG1881	PFAM PEBP family protein
ECWSU1_RS22835	COG1902	pentaerythritol trinitrate reductase activity
ECWSU1_RS22845	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS22865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECWSU1_RS22875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECWSU1_RS22880	COG2213	PTS system mannitol-specific
ECWSU1_RS22880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS22885	COG3414	Phosphotransferase system galactitol-specific IIB component
ECWSU1_RS22890	COG3775	system Galactitol-specific IIC component
ECWSU1_RS22895	COG0698	ribose 5-phosphate isomerase
ECWSU1_RS22900	COG1349	DNA-binding transcription factor activity
ECWSU1_RS22905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECWSU1_RS22910	COG3414	Phosphotransferase system galactitol-specific IIB component
ECWSU1_RS22915	COG3775	system Galactitol-specific IIC component
ECWSU1_RS22920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECWSU1_RS22925	COG1028	Short-chain dehydrogenase reductase Sdr
ECWSU1_RS22930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECWSU1_RS23325	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECWSU1_RS23665	COG5301	cellulose 1,4-beta-cellobiosidase activity
ECWSU1_RS23700	COG1309	transcriptional regulator
ECWSU1_RS23855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs