locus-tag class description ELJP9_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ELJP9_RS00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) ELJP9_RS00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ELJP9_RS00025 ENOG4105CC0 LysR family Transcriptional regulator ELJP9_RS00035 ENOG410667J hydrolase ELJP9_RS00040 ENOG4105EMF GntR family transcriptional regulator ELJP9_RS00045 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 ELJP9_RS00050 ENOG4108RTU Aldolase ELJP9_RS00055 ENOG4105CXK mandelate racemase muconate lactonizing ELJP9_RS00060 ENOG4105DJB Major Facilitator Superfamily ELJP9_RS00065 ENOG4105D99 atp gtp-binding protein ELJP9_RS00070 ENOG4105R2A (LipO)protein ELJP9_RS00080 ENOG4108SHS Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent (By similarity) ELJP9_RS00085 ENOG4105D0C transport protein ELJP9_RS00090 ENOG4105FDP GntR family transcriptional regulator ELJP9_RS00095 ENOG4105CI1 PTS System ELJP9_RS00100 ENOG4105F8D glycoside hydrolase family 4 ELJP9_RS00105 ENOG4105VG5 Membrane ELJP9_RS00110 ENOG4105JP4 Inner membrane protein yidG ELJP9_RS00125 ENOG4105W8I Transcriptional regulator ELJP9_RS00135 ENOG4105E5M Multidrug resistance protein D ELJP9_RS00165 ENOG4105C7K acetolactate synthase ELJP9_RS00170 ENOG4105M71 acetolactate synthase 1 regulatory subunit ELJP9_RS00175 ENOG4108KX4 response regulator ELJP9_RS00180 ENOG4105BZU Histidine kinase ELJP9_RS00185 ENOG4105CXY transporter ELJP9_RS00190 ENOG4105CXY transporter ELJP9_RS00195 ENOG4105CPT Alpha beta hydrolase ELJP9_RS00200 ENOG4108SAJ Protein of unknown function (DUF1198) ELJP9_RS00205 ENOG4106NZI LysR family Transcriptional regulator ELJP9_RS00225 ENOG4107SHS Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity) ELJP9_RS00235 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS00240 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS00245 ENOG4105CPC Aldo Keto reductase ELJP9_RS00255 ENOG4108UZ3 Transporter ELJP9_RS00260 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) ELJP9_RS00265 ENOG4105VCP PTS System ELJP9_RS00270 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS00275 ENOG4105CK1 PTS System ELJP9_RS00285 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS00295 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ELJP9_RS00300 ENOG4105BZS acriflavin resistance protein ELJP9_RS00305 ENOG4105C1P efflux transporter, rnd family, mfp subunit ELJP9_RS00310 ENOG41067SE Tetr family transcriptional regulator ELJP9_RS00315 ENOG4105VEV -acetyltransferase ELJP9_RS00320 ENOG4107XI7 Tetr family transcriptional regulator ELJP9_RS00330 ENOG4105D01 (LipO)protein ELJP9_RS00335 ENOG4105ENX hydrolase ELJP9_RS00340 ENOG4107RTG Major Facilitator superfamily ELJP9_RS00345 ENOG4105EQ2 LysR family Transcriptional regulator ELJP9_RS00350 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein ELJP9_RS00360 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) ELJP9_RS00365 ENOG4107SEY Conserved Protein ELJP9_RS00370 ENOG4105VT2 5-hydroxyisourate hydrolase ELJP9_RS00375 ENOG4108XDN Transcriptional regulator ELJP9_RS00390 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ELJP9_RS00405 ENOG4105CT4 transporter ELJP9_RS00410 ENOG4105CJQ hydrolase, family 31 ELJP9_RS00415 ENOG4105JV1 AsmA family ELJP9_RS00420 ENOG4105C2W permease ELJP9_RS00430 ENOG4105CB5 ATP-dependent DNA helicase recG ELJP9_RS00435 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase ELJP9_RS00440 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ELJP9_RS00460 ENOG4105EN6 Membrane ELJP9_RS00470 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) ELJP9_RS00475 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) ELJP9_RS00485 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) ELJP9_RS00490 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ELJP9_RS00495 ENOG4105W5Q DNA repair protein (RadC ELJP9_RS00500 ENOG4105KDC 50s ribosomal protein l28 ELJP9_RS00505 ENOG4105W0E 50S ribosomal protein L33 ELJP9_RS00510 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) ELJP9_RS00515 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) ELJP9_RS00520 ENOG4106WTF Glycosyl transferase, family 2 ELJP9_RS00525 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase ELJP9_RS00530 ENOG4105K64 Glycosyl transferase, family 2 ELJP9_RS00535 ENOG4105CPK Glycosyl transferase (Group 1 ELJP9_RS00540 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) ELJP9_RS00545 ENOG4105DKP glycosyl transferase, family 9 ELJP9_RS00570 ENOG4105D16 lipopolysaccharide heptosyltransferase i ELJP9_RS00575 ENOG4105XA0 heptosyltransferase ii ELJP9_RS00580 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) ELJP9_RS00585 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ELJP9_RS00590 ENOG4105CPQ Dehydrogenase ELJP9_RS00595 ENOG4108XNZ glycosyl transferase ELJP9_RS00600 ENOG4106WTF Glycosyl transferase, family 2 ELJP9_RS00605 ENOG4105PXI polysaccharide deacetylase ELJP9_RS00610 ENOG41063SB peptidase ELJP9_RS00615 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ELJP9_RS00620 ENOG4107YZP Rhodanese domain protein ELJP9_RS00625 ENOG4105VW4 glutaredoxin 3 ELJP9_RS00630 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) ELJP9_RS00635 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase ELJP9_RS00640 ENOG4105D7W serine acetyltransferase ELJP9_RS00645 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ELJP9_RS00650 ENOG4105D2S major facilitator superfamily ELJP9_RS00655 ENOG4105DMF Dehydrogenase ELJP9_RS00660 ENOG41073TP transcriptional regulator ELJP9_RS00665 ENOG4105DAA L-lactate ELJP9_RS00675 ENOG4108YYI Protein of unknown function (DUF2810) ELJP9_RS00680 ENOG4105E61 Mannitol repressor protein ELJP9_RS00690 ENOG4105CTS PTS system mannitol-specific ELJP9_RS00700 ENOG4105FP6 Protein of unknown function (DUF3302) ELJP9_RS00705 ENOG4105EFX secretion protein, HlyD family ELJP9_RS00710 ENOG4108U78 Glutathione S-transferase ELJP9_RS00720 ENOG4105EM7 Selenocysteine-specific translation elongation factor ELJP9_RS00725 ENOG4105C26 Dehydrogenase ELJP9_RS00730 ENOG4108Q2M Transcriptional regulator ELJP9_RS00735 ENOG4105GNX MltA-interacting MipA family protein ELJP9_RS00745 ENOG4105CT4 transporter ELJP9_RS00755 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase ELJP9_RS00760 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase ELJP9_RS00765 ENOG4105H6Q decarboxylase ELJP9_RS00770 ENOG4105CMG Carbohydrate kinase ELJP9_RS00780 ENOG4108M5W ELJP9_RS00785 ENOG4108R66 Conserved Protein ELJP9_RS00795 ENOG4105J4Q Transcriptional regulator ELJP9_RS00800 ENOG4108XIB electron transport protein ysaA ELJP9_RS00805 ENOG4105JKW Valine--pyruvate aminotransferase ELJP9_RS00810 ENOG4107T9C Alpha amylase catalytic region ELJP9_RS00815 ENOG4108UR8 BAX protein ELJP9_RS00820 ENOG4105T16 Transcriptional regulator (AraC family) ELJP9_RS00825 ENOG4108HWW ABC transporter ELJP9_RS00835 ENOG4105DFW ABC transporter ELJP9_RS00840 ENOG4105C93 Xylose Isomerase ELJP9_RS00845 ENOG4105CMG Carbohydrate kinase ELJP9_RS00850 ENOG4108RWI nicotinamidase ELJP9_RS00860 ENOG4105MEV Acyl-transferase ELJP9_RS00870 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit ELJP9_RS00875 ENOG4105C38 Glycyl-tRNA synthetase beta subunit ELJP9_RS00880 ENOG4105C5H ABC transporter ELJP9_RS00885 ENOG4105MVF Transcriptional regulator ELJP9_RS00890 ENOG4106JH6 (LipO)protein ELJP9_RS00900 ENOG4105C5I Dehydrogenase ELJP9_RS00910 ENOG4105D7K pfkb domain protein ELJP9_RS00920 ENOG4108M60 Transcriptional regulator ELJP9_RS00925 ENOG4108ZG0 Ompa motb domain protein ELJP9_RS00930 ENOG4107QY8 reductase ELJP9_RS00935 ENOG4105HNP -acetyltransferase ELJP9_RS00940 ENOG4108R3E Dna-3-methyladenine glycosylase i ELJP9_RS00945 ENOG4105EAX Putative lipase ELJP9_RS00950 ENOG4105FCD Major Facilitator ELJP9_RS00955 ENOG4105DIJ Phosphoethanolamine transferase ELJP9_RS00965 ENOG4105DEF Extracellular solute-binding protein, family 5 ELJP9_RS00970 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ELJP9_RS00975 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ELJP9_RS00980 ENOG4105C3U ABC transporter ELJP9_RS00985 ENOG4108JQ7 (ABC) transporter ELJP9_RS00990 ENOG4105CS9 pantothenic acid kinase ELJP9_RS01015 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) ELJP9_RS01020 ENOG4105PM1 preprotein translocase subunit SecE ELJP9_RS01025 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ELJP9_RS01040 ENOG4108VZM 50s ribosomal protein L10 ELJP9_RS01050 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ELJP9_RS01055 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ELJP9_RS01070 ENOG4106TD9 Diguanylate cyclase ELJP9_RS01075 ENOG4105D41 biosynthesis protein thiH ELJP9_RS01080 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) ELJP9_RS01085 ENOG4105WHD thiamine biosynthesis protein ThiS ELJP9_RS01090 ENOG4105D06 uba thif-type nad fad binding protein ELJP9_RS01095 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) ELJP9_RS01100 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) ELJP9_RS01105 ENOG4107MNS Has binding activity to the major sigma subunit of RNA polymerase. May be involved in replacement of the RNA polymerase sigma subunit from sigma-70 to sigma-S during the transition from exponential growth to the stationary phase (By similarity) ELJP9_RS01115 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) ELJP9_RS01125 ENOG4105R2J Conserved Protein ELJP9_RS01130 ENOG4105K70 DNA-binding protein ELJP9_RS01135 ENOG4108T8B Protein of unknown function (DUF1481) ELJP9_RS01140 ENOG4105C12 Phosphoribosylglycinamide synthetase ELJP9_RS01145 ENOG4105DC1 bifunctional purine biosynthesis protein purh ELJP9_RS01165 ENOG4105CVG Homoserine O-transsuccinylase ELJP9_RS01170 ENOG4107QP3 malate synthase g ELJP9_RS01175 ENOG4108I9X Isocitrate lyase ELJP9_RS01180 ENOG4105VS7 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) ELJP9_RS01185 ENOG41069M3 Transcriptional regulator ELJP9_RS01190 ENOG4105C3R Methionine synthase ELJP9_RS01195 ENOG4105EAM Na Pi-cotransporter ELJP9_RS01200 ENOG4105FE9 pseudouridine synthase ELJP9_RS01205 ENOG4108ZR5 Conserved Protein ELJP9_RS01210 ENOG4105C09 Bile acid ELJP9_RS01215 ENOG4105CFH Aspartokinase ELJP9_RS01230 ENOG4108MDC (LipO)protein ELJP9_RS01235 ENOG4108Q9C Periplasmic Protein ELJP9_RS01240 ENOG4105E3R (LipO)protein ELJP9_RS01245 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) ELJP9_RS01255 ENOG4108VY7 phosphate-starvation-inducible protein PsiE ELJP9_RS01260 ENOG4105EG2 ABC transporter, permease ELJP9_RS01265 ENOG4105D56 permease protein ELJP9_RS01270 ENOG4107FKK extracellular solute-binding protein family 1 ELJP9_RS01275 ENOG4108IJ9 (ABC) transporter ELJP9_RS01280 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) ELJP9_RS01285 ENOG4107W52 maltose operon periplasmic protein ELJP9_RS01290 ENOG4105VEI Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) ELJP9_RS01300 ENOG4105E55 glycerol-3-phosphate acyltransferase ELJP9_RS01305 ENOG41080IJ Diacylglycerol kinase ELJP9_RS01310 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) ELJP9_RS01315 ENOG4107R73 Mate efflux family protein ELJP9_RS01320 ENOG4105VDW Csbd family ELJP9_RS01325 ENOG4105MYN Zinc uptake regulation protein ELJP9_RS01340 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ELJP9_RS01345 ENOG4105P4Z Phage shock protein G ELJP9_RS01350 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein ELJP9_RS01355 ENOG4105CDU Replicative dna helicase ELJP9_RS01360 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ELJP9_RS01365 ENOG4106Z1T Nicotinamide Mononucleotide Transporter ELJP9_RS01370 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase ELJP9_RS01375 ENOG4105CGF Aromatic amino acid aminotransferase ELJP9_RS01380 ENOG4105F0S class B acid phosphatase ELJP9_RS01385 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme ELJP9_RS01390 ENOG4105MSB protein, conserved in bacteria ELJP9_RS01395 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ELJP9_RS01400 ENOG4108UUM single-stranded DNA-binding protein ELJP9_RS01405 ENOG4105PMV Membrane ELJP9_RS01410 ENOG4105BZU Histidine kinase ELJP9_RS01420 ENOG4108W3Q Transcriptional regulator ELJP9_RS01425 ENOG4108Z4X TRANSCRIPTIONal ELJP9_RS01430 ENOG4108RXX maleylacetoacetate isomerase ELJP9_RS01435 ENOG4105C7N Xanthine uracil vitamin C permease ELJP9_RS01440 ENOG4105EEQ Na H antiporter ELJP9_RS01445 ENOG4105CMU LysR family (Transcriptional regulator ELJP9_RS01450 ENOG4105VAW lrga family ELJP9_RS01455 ENOG41067MG lrgb family ELJP9_RS01460 ENOG4107QN1 sodium solute ELJP9_RS01465 ENOG41062QD Membrane ELJP9_RS01470 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ELJP9_RS01475 ENOG4105CK2 sodium dicarboxylate symporter ELJP9_RS01480 ENOG41082ND Uncharacterized protein yjcO ELJP9_RS01500 ENOG4105D2N Aldolase ELJP9_RS01510 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ELJP9_RS01515 ENOG4105CNN ABC, transporter ELJP9_RS01520 ENOG4105C2J ABC transporter ELJP9_RS01525 ENOG4105CQZ Histidine kinase ELJP9_RS01530 ENOG4107TFG D-allose kinase ELJP9_RS01535 ENOG4105UP7 3-epimerase ELJP9_RS01540 ENOG4105CNN ABC, transporter ELJP9_RS01545 ENOG4105C2J ABC transporter ELJP9_RS01555 ENOG4105NYY transcriptional regulator, RpiR ELJP9_RS01560 ENOG4108YZG isomerase ELJP9_RS01570 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein ELJP9_RS01575 ENOG410849A acetyltransferase, (GNAT) family ELJP9_RS01580 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) ELJP9_RS01585 ENOG4105FD8 phosphonate metabolism protein PhnM ELJP9_RS01590 ENOG4105HRV phosphonate c-p lyase system protein phnl ELJP9_RS01595 ENOG4105ENV phosphonate C-P lyase system protein PhnK ELJP9_RS01600 ENOG4105FT8 Phosphonate metabolism ELJP9_RS01605 ENOG4105EKV Phosphonate metabolism protein ELJP9_RS01610 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH ELJP9_RS01615 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG ELJP9_RS01620 ENOG4107RJJ Transcriptional regulator ELJP9_RS01630 ENOG4105EHI Phosphonate ABC transporter, periplasmic ELJP9_RS01635 ENOG4105D5T phosphonate abc transporter ELJP9_RS01640 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase ELJP9_RS01645 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ELJP9_RS01650 ENOG4108F5E vimentin ELJP9_RS01655 ENOG4108YIV ELJP9_RS01660 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) ELJP9_RS01665 ENOG4105CSH Transporter ELJP9_RS01670 ENOG4105D7X high-affinity nickel-transporter ELJP9_RS01700 ENOG4108SIC Transcriptional regulator ELJP9_RS01705 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) ELJP9_RS01715 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter ELJP9_RS01720 ENOG4108IJ0 Aspartate ammonia-lyase ELJP9_RS01725 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 ELJP9_RS01730 ENOG4105DVH amino acid ELJP9_RS01740 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) ELJP9_RS01745 ENOG4108ZVF (LipO)protein ELJP9_RS01750 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ELJP9_RS01755 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) ELJP9_RS01760 ENOG4106BSU Entericidin B ELJP9_RS01785 ENOG4106FGB Beta-lactamase ELJP9_RS01790 ENOG4105ETT transcriptional Regulator, LysR family ELJP9_RS01800 ENOG4108WJH Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) ELJP9_RS01805 ENOG4105E33 succinate dehydrogenase ELJP9_RS01810 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) ELJP9_RS01815 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) ELJP9_RS01820 ENOG4107SC7 Inner membrane transporter yjeM ELJP9_RS01825 ENOG4105EGS Mechanosensitive ion channel ELJP9_RS01840 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) ELJP9_RS01860 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ELJP9_RS01865 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) ELJP9_RS01870 ENOG4105K8N protein family UPF0079, ATPase ELJP9_RS01875 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ELJP9_RS01880 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) ELJP9_RS01890 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ELJP9_RS01895 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ELJP9_RS01900 ENOG4107QJR hflk protein ELJP9_RS01905 ENOG4105EPW hflc protein ELJP9_RS01920 ENOG4105KPV Transcriptional regulator ELJP9_RS01925 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ELJP9_RS01930 ENOG4105C2N RNA methyltransferase TrmH family group 3 ELJP9_RS01935 ENOG4105CSH Transporter ELJP9_RS01940 ENOG4105CSU acyl-Coa dehydrogenase ELJP9_RS01945 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS01950 ENOG4105S17 UPF0379 protein yjfN ELJP9_RS01955 ENOG4105WSB biofilm stress and motility protein A ELJP9_RS01960 ENOG4108MXZ Esterase ELJP9_RS02005 ENOG4105KIT UPF0379 protein yjfY ELJP9_RS02010 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) ELJP9_RS02015 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) ELJP9_RS02020 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) ELJP9_RS02025 ENOG4105K9Q Binds to the 23S rRNA (By similarity) ELJP9_RS02030 ENOG4108IPJ Membrane ELJP9_RS02035 ENOG4105FHY Opacity-associated protein A ELJP9_RS02040 ENOG4108V1T peptidylprolyl cis-trans isomerase ELJP9_RS02050 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) ELJP9_RS02055 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS02060 ENOG4105DXC membrane ELJP9_RS02070 ENOG4105ECR NmrA family ELJP9_RS02075 ENOG4105KVH Transcriptional regulator ELJP9_RS02080 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic ELJP9_RS02085 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase ELJP9_RS02090 ENOG4108UUE Transcriptional regulator ELJP9_RS02095 ENOG41061GZ Protein of unknown function (DUF1107) ELJP9_RS02100 ENOG4105C37 (CBS) domain ELJP9_RS02110 ENOG4107TYG Oxidoreductase domain-containing protein ELJP9_RS02135 ENOG4107QXP Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ELJP9_RS02140 ENOG4105CFU surface antigen ELJP9_RS02145 ENOG4105MA0 exported protein ELJP9_RS02150 ENOG4108ZHD aig2 family ELJP9_RS02160 ENOG4105F0N pyrophosphate phospho-hydrolase ELJP9_RS02165 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator ELJP9_RS02170 ENOG4105C2J ABC transporter ELJP9_RS02175 ENOG4107R9N ABC transporter ELJP9_RS02180 ENOG41062B0 ABC transporter, permease ELJP9_RS02185 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS02200 ENOG4105DFU Cell wall formation (By similarity) ELJP9_RS02205 ENOG4105N42 UPF0307 protein ELJP9_RS02210 ENOG4105CMS peptidase U62, modulator of DNA gyrase ELJP9_RS02215 ENOG4108XVM Cytochrome b(562) ELJP9_RS02245 ENOG41069H0 dihydroorotase EC 3.5.2.3 ELJP9_RS02265 ENOG4105EMD TRANSCRIPTIONal ELJP9_RS02275 ENOG4105K4U addiction module toxin, RelE StbE family ELJP9_RS02280 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) ELJP9_RS02285 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase ELJP9_RS02290 ENOG4105DM4 PTS System ELJP9_RS02300 ENOG410863U PTS System ELJP9_RS02305 ENOG4106KNT transcriptional regulator ELJP9_RS02315 ENOG4105CG3 alpha amylase, catalytic region ELJP9_RS02320 ENOG4105C5Y PTS System ELJP9_RS02325 ENOG4105D4X repressor ELJP9_RS02335 ENOG4105E2D ec 3.2.1.52 ELJP9_RS02340 ENOG4105KME endoribonuclease L-psp ELJP9_RS02345 ENOG4108R9M Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity) ELJP9_RS02350 ENOG4105CXT aspartate transcarbamylase ELJP9_RS02355 ENOG41077AM PyrBI operon attenuator ELJP9_RS02360 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) ELJP9_RS02365 ENOG4105CSX c4-dicarboxylate anaerobic carrier ELJP9_RS02370 ENOG4105DBV ornithine carbamoyltransferase ELJP9_RS02375 ENOG4105C5B carbamate kinase ELJP9_RS02380 ENOG4105CEU Arginine dihydrolase ELJP9_RS02385 ENOG4105XEP YhcH YjgK YiaL family protein ELJP9_RS02390 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ELJP9_RS02395 ENOG4105C01 Dihydroxy-acid dehydratase ELJP9_RS02400 ENOG4105CT4 transporter ELJP9_RS02405 ENOG4105DSG hydrolase family 43 ELJP9_RS02410 ENOG4107HP6 Transcriptional regulator ELJP9_RS02415 ENOG4105DBV ornithine carbamoyltransferase ELJP9_RS02420 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) ELJP9_RS02425 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase ELJP9_RS02495 ENOG4105DTA methyltransferase ELJP9_RS02510 ENOG4106NDP Transcriptional regulator ELJP9_RS02515 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) ELJP9_RS02520 ENOG4108HKT sucrose-6-phosphate hydrolase ELJP9_RS02540 ENOG4105D7K pfkb domain protein ELJP9_RS02560 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS02570 ENOG4105CT4 transporter ELJP9_RS02575 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase ELJP9_RS02580 ENOG4105MVE transcriptional regulator ELJP9_RS02585 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ELJP9_RS02615 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ELJP9_RS02635 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) ELJP9_RS02640 ENOG410642W LysR family Transcriptional regulator ELJP9_RS02645 ENOG4105C26 Dehydrogenase ELJP9_RS02660 ENOG4108ZHR arsR family transcriptional regulator ELJP9_RS02680 ENOG4106BRA Membrane ELJP9_RS02690 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) ELJP9_RS02695 ENOG4105C26 Dehydrogenase ELJP9_RS02715 ENOG4105CKI cobalamin synthesis protein ELJP9_RS02720 ENOG4105VCD cytoplasmic protein ELJP9_RS02725 ENOG4105D22 carbon starvation protein ELJP9_RS02735 ENOG4107UWN reductase ELJP9_RS02740 ENOG4105EFA 4-hydroxyphenylacetate ELJP9_RS02755 ENOG4105CNV Aldolase ELJP9_RS02770 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase ELJP9_RS02775 ENOG4105C26 Dehydrogenase ELJP9_RS02780 ENOG4105ERH Fumarylacetoacetate hydrolase ELJP9_RS02785 ENOG4108V8F Transcriptional regulator, MarR family ELJP9_RS02790 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS02795 ENOG4105XYF acetyltransferase ELJP9_RS02825 ENOG4105RI1 glycoprotein receptor ELJP9_RS02830 ENOG4106CVF DNA replication protein ELJP9_RS02835 ENOG4108PM0 it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity) ELJP9_RS02840 ENOG4108ZHJ Organic hydroperoxide resistance protein ELJP9_RS02845 ENOG4105K56 Transcriptional regulator ELJP9_RS02855 ENOG4107XM3 UPF0442 protein ELJP9_RS02860 ENOG4105DWK Membrane ELJP9_RS02865 ENOG4108N8T regulatoR ELJP9_RS02870 ENOG4108T94 DNA-binding transcriptional activator BglJ ELJP9_RS02875 ENOG4108UIN ybak prolyl-trna synthetase associated region ELJP9_RS02880 ENOG4105CK1 PTS System ELJP9_RS02885 ENOG4108819 ferric iron reductase ELJP9_RS02890 ENOG4106TD9 Diguanylate cyclase ELJP9_RS02895 ENOG4105YBH Protein of unknown function (DUF1435) ELJP9_RS02915 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) ELJP9_RS02920 ENOG4108WPU DNA polymerase III subunit psi ELJP9_RS02925 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ELJP9_RS02930 ENOG4105PAD Hydrolase ELJP9_RS02935 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) ELJP9_RS02940 ENOG4105K3G Periplasmic Protein ELJP9_RS02950 ENOG4108NRW Phospholipase, patatin family ELJP9_RS02955 ENOG4105EYA deoxyribonuclease ELJP9_RS02960 ENOG41076CZ activating enzyme ELJP9_RS02965 ENOG4105G0K glycine radical enzyme YjjI family ELJP9_RS02975 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) ELJP9_RS02985 ENOG4105D3A purine nucleoside phosphorylase DeoD-type ELJP9_RS03000 ENOG4105E6S usher protein( ELJP9_RS03005 ENOG4108S1B Periplasmic chaperone protein ELJP9_RS03015 ENOG4105UMR response to DNA damage stimulus ELJP9_RS03020 ENOG4106AJS Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon ELJP9_RS03025 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) ELJP9_RS03030 ENOG41062Z9 Membrane ELJP9_RS03035 ENOG4105EAC phosphoserine phosphatase ELJP9_RS03040 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ELJP9_RS03045 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase ELJP9_RS03050 ENOG4105CIS alcohol dehydrogenase ELJP9_RS03060 ENOG4105C5H ABC transporter ELJP9_RS03065 ENOG4107SC1 transglycosylase ELJP9_RS03070 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) ELJP9_RS03075 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) ELJP9_RS03080 ENOG4105CVJ phosphoglycerate mutase ELJP9_RS03085 ENOG4105UEI Transcriptional Regulator AraC Family ELJP9_RS03090 ENOG4108RH0 Crea protein ELJP9_RS03095 ENOG4105E3W Two component transcriptional regulator (Winged helix family ELJP9_RS03100 ENOG4105EB3 Histidine kinase ELJP9_RS03105 ENOG4105CT7 inner membrane cred family protein ELJP9_RS03110 ENOG41065U4 response regulator ELJP9_RS03115 ENOG410759A ELJP9_RS03120 ENOG4106FVC RNA methyltransferase ELJP9_RS03130 ENOG4105CFH Aspartokinase ELJP9_RS03140 ENOG4105D98 threonine synthase ELJP9_RS03145 ENOG41062C6 Protein of unknown function (DUF2502) ELJP9_RS03150 ENOG4105D1Q UPF0246 protein ELJP9_RS03160 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ELJP9_RS03165 ENOG4108RIR Molybdenum cofactor biosynthesis protein ELJP9_RS03170 ENOG4105CSH Transporter ELJP9_RS03175 ENOG4106HK8 GPR1 FUN34 yaaH family protein ELJP9_RS03180 ENOG4105CFG Acts as a chaperone (By similarity) ELJP9_RS03190 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) ELJP9_RS03195 ENOG41063Z6 transcriptional regulator, lysR family ELJP9_RS03200 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) ELJP9_RS03210 ENOG4105DTN riboflavin biosynthesis protein ribF ELJP9_RS03215 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ELJP9_RS03220 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) ELJP9_RS03225 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase ELJP9_RS03230 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) ELJP9_RS03235 ENOG4108Y83 glucose-6-phosphate isomerase ELJP9_RS03245 ENOG4105F3R pts system mannose fructose sorbose family iid ELJP9_RS03250 ENOG4105ETZ PTS System ELJP9_RS03255 ENOG4108IQ3 PTS system ELJP9_RS03270 ENOG4107P2S Transcriptional regulator ELJP9_RS03275 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) ELJP9_RS03280 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain ELJP9_RS03285 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain ELJP9_RS03290 ENOG4105M5B (LipO)protein ELJP9_RS03295 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF ELJP9_RS03300 ENOG4105CKD glutathione-regulated potassium-efflux system protein ELJP9_RS03305 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) ELJP9_RS03310 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) ELJP9_RS03315 ENOG4105NWN ApaG protein ELJP9_RS03320 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) ELJP9_RS03325 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) ELJP9_RS03330 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) ELJP9_RS03335 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) ELJP9_RS03340 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) ELJP9_RS03345 ENOG4105D3G Pseudouridine synthase ELJP9_RS03350 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) ELJP9_RS03355 ENOG4105CQ2 DNA polymerase ELJP9_RS03360 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase ELJP9_RS03365 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) ELJP9_RS03370 ENOG4105EF1 ribulokinase ELJP9_RS03380 ENOG4108KF1 Membrane ELJP9_RS03390 ENOG4106SMU thiamine transporter membrane protein ELJP9_RS03410 ENOG4105S8Q sugar efflux transporter ELJP9_RS03415 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) ELJP9_RS03420 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) ELJP9_RS03425 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) ELJP9_RS03430 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ELJP9_RS03440 ENOG41064T2 transcriptional regulator, lysR family ELJP9_RS03445 ENOG4105C7K acetolactate synthase ELJP9_RS03450 ENOG4108ZP8 Acetolactate synthase small subunit ELJP9_RS03455 ENOG4107B7Y DNA-binding transcriptional regulator FruR ELJP9_RS03460 ENOG4108V6E Cell division protein mraZ ELJP9_RS03470 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) ELJP9_RS03475 ENOG4105CJN penicillin-binding protein ELJP9_RS03480 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ELJP9_RS03485 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) ELJP9_RS03490 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) ELJP9_RS03500 ENOG4105CNI cell division protein FtsW ELJP9_RS03505 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) ELJP9_RS03510 ENOG4105DFU Cell wall formation (By similarity) ELJP9_RS03515 ENOG4105CPF Cell wall formation (By similarity) ELJP9_RS03520 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) ELJP9_RS03525 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ELJP9_RS03530 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ELJP9_RS03535 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ELJP9_RS03540 ENOG4106Q9Y Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity) ELJP9_RS03545 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving ELJP9_RS03550 ENOG4105M6F mutator MutT protein ELJP9_RS03555 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) ELJP9_RS03560 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) ELJP9_RS03565 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ELJP9_RS03570 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ELJP9_RS03575 ENOG4105D7Q type ii secretion system ELJP9_RS03580 ENOG4107QHF type ii secretion system protein e ELJP9_RS03585 ENOG4108ZUW Major pilin subunit ELJP9_RS03595 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ELJP9_RS03600 ENOG4106A72 regulatory protein AmpE ELJP9_RS03605 ENOG4105CUK Alpha-N-arabinofuranosidase (EC 3.2.1.55) ELJP9_RS03610 ENOG4105CT4 transporter ELJP9_RS03615 ENOG4105C85 amino acid ELJP9_RS03620 ENOG41073TP transcriptional regulator ELJP9_RS03625 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) ELJP9_RS03630 ENOG4107QSN dihydrolipoamide acetyltransferase ELJP9_RS03635 ENOG4107QN2 dihydrolipoyl dehydrogenase ELJP9_RS03645 ENOG4108NST exported protein ELJP9_RS03650 ENOG4107QIJ Aconitate hydratase 2 ELJP9_RS03660 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) ELJP9_RS03665 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) ELJP9_RS03670 ENOG4108ZRK uncharacterized protein yacC ELJP9_RS03675 ENOG4105E3B Multicopper oxidase ELJP9_RS03680 ENOG4105DZG Dehydrogenase ELJP9_RS03685 ENOG4108UGV hypoxanthine phosphoribosyltransferase ELJP9_RS03695 ENOG4105DA5 (ABC) transporter ELJP9_RS03700 ENOG4105E3A (ABC) transporter ELJP9_RS03705 ENOG4108YTN IIa component ELJP9_RS03710 ENOG4107BJW polysaccharide deacetylase ELJP9_RS03715 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) ELJP9_RS03720 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) ELJP9_RS03730 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ELJP9_RS03735 ENOG4105DJ0 Poly(A) Polymerase ELJP9_RS03740 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) ELJP9_RS03750 ENOG4105PW4 Sugar fermentation stimulation protein homolog ELJP9_RS03755 ENOG4107XID 2'-5' rna ligase ELJP9_RS03760 ENOG4105CQ7 ATP-dependent helicase ELJP9_RS03765 ENOG4105BZ4 penicillin-binding protein ELJP9_RS03770 ENOG4105E0K tonB-dependent siderophore receptor ELJP9_RS03775 ENOG4105E0A ABC, transporter ELJP9_RS03780 ENOG4105J76 Periplasmic binding protein ELJP9_RS03785 ENOG4105S6R Iron-hydroxamate transporter permease subunit ELJP9_RS03790 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase ELJP9_RS03805 ENOG4105EN6 Membrane ELJP9_RS03810 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) ELJP9_RS03820 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein ELJP9_RS03825 ENOG4105C0H protease ELJP9_RS03830 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR ELJP9_RS03835 ENOG4108T8E UPF0325 protein ELJP9_RS03840 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) ELJP9_RS03845 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) ELJP9_RS03850 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ELJP9_RS03860 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) ELJP9_RS03865 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) ELJP9_RS03875 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) ELJP9_RS03885 ENOG4105KNE Phosphatidate cytidylyltransferase ELJP9_RS03890 ENOG4105DZP Membrane-associated zinc metalloprotease ELJP9_RS03895 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ELJP9_RS03900 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) ELJP9_RS03905 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ELJP9_RS03910 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) ELJP9_RS03920 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) ELJP9_RS03925 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ELJP9_RS03930 ENOG4105C0B DNA polymerase III (alpha subunit) ELJP9_RS03940 ENOG4105CXN decarboxylase ELJP9_RS03945 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase ELJP9_RS03950 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ELJP9_RS03955 ENOG4105M1T rho-binding antiterminator ELJP9_RS03960 ENOG4105W1I UPF0253 protein ELJP9_RS03965 ENOG4108VWS Yaeq family ELJP9_RS03970 ENOG4108YZN class I peptide chain release factor ELJP9_RS03975 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion ELJP9_RS03980 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) ELJP9_RS03985 ENOG4108R96 Methyltransferase, YaeB family ELJP9_RS03990 ENOG4108R8X outer membrane lipoprotein ELJP9_RS03995 ENOG4105D01 (LipO)protein ELJP9_RS04000 ENOG4108UMI ABC transporter, permease ELJP9_RS04005 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS04010 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase ELJP9_RS04045 ENOG4105CV8 reductase ELJP9_RS04050 ENOG4105HEI LysR family (Transcriptional regulator ELJP9_RS04055 ENOG4105F27 Major Facilitator ELJP9_RS04060 ENOG4107NA1 Endonuclease Exonuclease phosphatase ELJP9_RS04065 ENOG4105F2W methyltransferase ELJP9_RS04070 ENOG4105E9H Lytic Murein transglycosylase ELJP9_RS04075 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ELJP9_RS04080 ENOG4105D1A Methyltransferase ELJP9_RS04090 ENOG4107RZZ dna polymerase iii epsilon subunit ELJP9_RS04105 ENOG4105C3U ABC transporter ELJP9_RS04110 ENOG4108JQ7 (ABC) transporter ELJP9_RS04125 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ELJP9_RS04130 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ELJP9_RS04135 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ELJP9_RS04140 ENOG4107QPN acyl-Coa dehydrogenase ELJP9_RS04150 ENOG4105E7A Glutamine amidotransferase ELJP9_RS04155 ENOG4105F7V ErfK ybiS ycfS ynhG family protein ELJP9_RS04170 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) ELJP9_RS04175 ENOG4105F5D NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) ELJP9_RS04180 ENOG4108IUB NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) ELJP9_RS04185 ENOG4105D26 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity) ELJP9_RS04195 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ELJP9_RS04200 ENOG4105CIN aminoacyl-histidine dipeptidase ELJP9_RS04205 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) ELJP9_RS04210 ENOG4105V1F Fermentation respiration switch protein ELJP9_RS04220 ENOG4105FCK Membrane ELJP9_RS04225 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) ELJP9_RS04230 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) ELJP9_RS04250 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving ELJP9_RS04275 ENOG4106W3I PA-I galactophilic lectin ELJP9_RS04280 ENOG4106W3I PA-I galactophilic lectin ELJP9_RS04290 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ELJP9_RS04295 ENOG4105CC0 LysR family Transcriptional regulator ELJP9_RS04305 ENOG410829K Lysine exporter protein (Lyse ygga) ELJP9_RS04310 ENOG4105DS0 Transcriptional regulator, Crp Fnr family ELJP9_RS04325 ENOG4105DHT Metal Dependent Phosphohydrolase ELJP9_RS04335 ENOG4105CW0 outer membrane usher protein ELJP9_RS04340 ENOG4108MQF Chaperone ELJP9_RS04350 ENOG4106TD9 Diguanylate cyclase ELJP9_RS04355 ENOG4105F4G Membrane ELJP9_RS04360 ENOG4108IQI permease ELJP9_RS04365 ENOG4107QK5 Homocysteine s-methyltransferase ELJP9_RS04370 ENOG4106FTQ Taurine ABC transporter, periplasmic ELJP9_RS04375 ENOG4108ETV ABC transporter ELJP9_RS04380 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ELJP9_RS04385 ENOG4105E2B Taurine dioxygenase ELJP9_RS04395 ENOG4105D52 delta-aminolevulinic acid dehydratase ELJP9_RS04400 ENOG4108NSE outer membrane autotransporter barrel ELJP9_RS04405 ENOG4108PNB DNA-binding transcriptional regulator ELJP9_RS04410 ENOG4107R6D beta-lactam binding protein AmpH ELJP9_RS04420 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 ELJP9_RS04425 ENOG4107QS8 (LipO)protein ELJP9_RS04435 ENOG4105UNH Membrane ELJP9_RS04440 ENOG4105CPF Cell wall formation (By similarity) ELJP9_RS04455 ENOG4105RZQ Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway (By similarity) ELJP9_RS04460 ENOG4105G6Z alkaline phosphatase ELJP9_RS04465 ENOG4105VIF phosphate starvation-inducible protein ELJP9_RS04470 ENOG4105BZU Histidine kinase ELJP9_RS04475 ENOG4105II7 pyrroline-5-carboxylate reductase ELJP9_RS04480 ENOG4108UPT UPF0178 protein ELJP9_RS04485 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) ELJP9_RS04490 ENOG4105SS3 ELJP9_RS04495 ENOG4105HBA AroM protein ELJP9_RS04500 ENOG4105NBK UPF0345 protein ELJP9_RS04510 ENOG4105DKQ ROK family ELJP9_RS04515 ENOG4105EYH Exonuclease ELJP9_RS04520 ENOG4107RH8 nuclease SbcCD subunit D ELJP9_RS04530 ENOG4105BZU Histidine kinase ELJP9_RS04535 ENOG4105CWM branched-chain amino acid transport system II carrier protein ELJP9_RS04540 ENOG4105C85 amino acid ELJP9_RS04545 ENOG4107R28 alpha amylase, catalytic region ELJP9_RS04550 ENOG4105CHJ isochorismatase hydrolase ELJP9_RS04565 ENOG4105D3R alkyl hydroperoxide reductase ELJP9_RS04570 ENOG4108ZYK Acyl carrier protein phosphodiesterase ELJP9_RS04580 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) ELJP9_RS04585 ENOG4105VIE preprotein translocase, subunit YajC ELJP9_RS04590 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ELJP9_RS04595 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ELJP9_RS04610 ENOG4105DRB nucleoside-specific channel-forming protein ELJP9_RS04615 ENOG4108KIC (LipO)protein ELJP9_RS04620 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) ELJP9_RS04630 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) ELJP9_RS04635 ENOG4107YIM Involved in the transcription termination process (By similarity) ELJP9_RS04640 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) ELJP9_RS04645 ENOG4105CPC Aldo Keto reductase ELJP9_RS04650 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) ELJP9_RS04655 ENOG4105CTB Polyprenyl synthetase ELJP9_RS04660 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ELJP9_RS04670 ENOG4107S0N DJ-1 family ELJP9_RS04675 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) ELJP9_RS04685 ENOG4107RDB Major Facilitator ELJP9_RS04690 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) ELJP9_RS04695 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) ELJP9_RS04700 ENOG4105CCU oxidase (Subunit III) ELJP9_RS04710 ENOG4105E2S oxidase) subunit II ELJP9_RS04715 ENOG4105EYM Major Facilitator superfamily ELJP9_RS04720 ENOG4105IEY (LipO)protein ELJP9_RS04725 ENOG4105M85 Bola protein ELJP9_RS04735 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation ELJP9_RS04745 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) ELJP9_RS04750 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) ELJP9_RS04755 ENOG4105K70 DNA-binding protein ELJP9_RS04760 ENOG4105EIN peptidylprolyl cis-trans isomerase ELJP9_RS04765 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein ELJP9_RS04770 ENOG4108TGP Thioesterase superfamily protein ELJP9_RS04775 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) ELJP9_RS04785 ENOG4108AZI Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity) ELJP9_RS04795 ENOG4108XM1 transcriptional regulator AsnC family ELJP9_RS04800 ENOG4105BZ1 (ABC) transporter ELJP9_RS04810 ENOG4108YZA Nitrogen regulatory protein pii ELJP9_RS04815 ENOG4105BZU Histidine kinase ELJP9_RS04820 ENOG4105C29 acyl-CoA thioesterase ELJP9_RS04825 ENOG4108MNP Glycoprotein polysaccharide metabolism ELJP9_RS04830 ENOG41080UX Methyltransferase ELJP9_RS04850 ENOG4107U9B transcriptional regulator ELJP9_RS04855 ENOG4108VW9 Membrane ELJP9_RS04860 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS04870 ENOG41061MD high-affinity nickel-transporter ELJP9_RS04880 ENOG41066DG (EAL) domain protein ELJP9_RS04885 ENOG4105NRA 50s ribosomal protein l31 type b ELJP9_RS04890 ENOG4105YK5 50S ribosomal protein L36 ELJP9_RS04905 ENOG4105GSJ Inner membrane protein ylaC ELJP9_RS04910 ENOG4108UW5 maltose o-acetyltransferase ELJP9_RS04915 ENOG4105KF5 hemolysin expression-modulating protein ELJP9_RS04920 ENOG4108UKR Biofilm formation regulator YbaJ ELJP9_RS04925 ENOG4105BZS acriflavin resistance protein ELJP9_RS04930 ENOG4105C1P efflux transporter, rnd family, mfp subunit ELJP9_RS04935 ENOG4107XI7 Tetr family transcriptional regulator ELJP9_RS04940 ENOG4105EGS Mechanosensitive ion channel ELJP9_RS04945 ENOG4106428 Protein of unknown function (DUF2496) ELJP9_RS04950 ENOG4108URS primosomal replication protein n'' ELJP9_RS04955 ENOG4105WD1 Membrane ELJP9_RS04960 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) ELJP9_RS04970 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) ELJP9_RS04975 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) ELJP9_RS04980 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) ELJP9_RS04985 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) ELJP9_RS04990 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) ELJP9_RS04995 ENOG4107RE1 Inosine-guanosine kinase ELJP9_RS05000 ENOG4105CKD glutathione-regulated potassium-efflux system protein ELJP9_RS05005 ENOG4105EU0 Major facilitator Superfamily ELJP9_RS05010 ENOG4105CGH 5'-nucleotidase ELJP9_RS05015 ENOG4108Z66 YbaK ebsC protein ELJP9_RS05020 ENOG4105MBR gumn family ELJP9_RS05025 ENOG4105C59 p-type ATPase ELJP9_RS05030 ENOG4108Z6Z Transcriptional regulator ELJP9_RS05035 ENOG4105G5H Membrane ELJP9_RS05040 ENOG4107QX8 SPFH domain, Band 7 family protein ELJP9_RS05045 ENOG41083J0 (ABC) transporter ELJP9_RS05050 ENOG4105C4B ABC transporter, permease ELJP9_RS05055 ENOG4107QR8 Thioredoxin ELJP9_RS05060 ENOG4105E1F short-chain dehydrogenase reductase ELJP9_RS05065 ENOG4108UJV acyl-CoA thioesterase i ELJP9_RS05070 ENOG4108I0Y (ABC) transporter ELJP9_RS05075 ENOG4105CV6 ABC transporter, permease ELJP9_RS05090 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ELJP9_RS05095 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ELJP9_RS05105 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) ELJP9_RS05110 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ELJP9_RS05115 ENOG4105C8N cysteinyl-tRNA synthetase ELJP9_RS05120 ENOG4105S2T inner membrane protein YbcI ELJP9_RS05130 ENOG4105CI1 PTS System ELJP9_RS05135 ENOG4105WQ3 Rna-binding protein ELJP9_RS05140 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) ELJP9_RS05145 ENOG4108WDE Fimbrial protein ELJP9_RS05150 ENOG4105NJT Fimbrial protein ELJP9_RS05155 ENOG4108AF8 Chaperone ELJP9_RS05160 ENOG4105CW0 outer membrane usher protein ELJP9_RS05165 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) ELJP9_RS05170 ENOG4108ZI2 Fimbrial protein ELJP9_RS05175 ENOG4108Q9V regulatoR ELJP9_RS05220 ENOG4105C85 amino acid ELJP9_RS05225 ENOG4105EAA nucleoside ELJP9_RS05235 ENOG4105CK5 oxidoreductase ELJP9_RS05245 ENOG4105CUY Mechanosensitive ion channel ELJP9_RS05265 ENOG4108RCM Nitroreductase ELJP9_RS05270 ENOG4105MSB protein, conserved in bacteria ELJP9_RS05275 ENOG41067SE Tetr family transcriptional regulator ELJP9_RS05285 ENOG4105SUT Transcriptional Regulator AraC Family ELJP9_RS05290 ENOG4105WQ6 Membrane ELJP9_RS05300 ENOG4105ENT Efflux transporter rnd family, mfp subunit ELJP9_RS05310 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) ELJP9_RS05320 ENOG4105R1U AraC Family Transcriptional Regulator ELJP9_RS05325 ENOG4105DSW Fusaric acid resistance protein ELJP9_RS05335 ENOG4105Y49 secretion protein, HlyD family ELJP9_RS05355 ENOG4108WQH regulatoR ELJP9_RS05360 ENOG4108W2Y isochorismatase ELJP9_RS05365 ENOG4105ECQ AraC Family Transcriptional Regulator ELJP9_RS05405 ENOG41068CG regulatoR ELJP9_RS05410 ENOG4105BZU Histidine kinase ELJP9_RS05430 ENOG4109066 lysm domain bon superfamily protein ELJP9_RS05435 ENOG4105VP5 Bacterial protein of unknown function (DUF937) ELJP9_RS05440 ENOG4105CF7 AraC family transcriptional regulator ELJP9_RS05445 ENOG4105E1F short-chain dehydrogenase reductase ELJP9_RS05450 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF ELJP9_RS05455 ENOG4105C1P efflux transporter, rnd family, mfp subunit ELJP9_RS05485 ENOG4108V06 Glutathione peroxidase ELJP9_RS05490 ENOG4105CHR reductase ELJP9_RS05510 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ELJP9_RS05520 ENOG4105D64 Mechanosensitive ion channel ELJP9_RS05540 ENOG4105GZI Transcriptional regulator ELJP9_RS05545 ENOG4108K3A Glutathione S-transferase ELJP9_RS05550 ENOG4105CHR reductase ELJP9_RS05560 ENOG4105KVH Transcriptional regulator ELJP9_RS05565 ENOG4105DIJ Phosphoethanolamine transferase ELJP9_RS05570 ENOG4105JAB phenazine biosynthesis protein, phzf family ELJP9_RS05590 ENOG4105WH1 Two component transcriptional regulator luxr family ELJP9_RS05595 ENOG4105BZU Histidine kinase ELJP9_RS05600 ENOG4105X2V dna damage-inducible protein ELJP9_RS05605 ENOG4105Z4Q MltA-interacting MipA family protein ELJP9_RS05610 ENOG4105XJC Two component transcriptional regulator (Winged helix family ELJP9_RS05620 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) ELJP9_RS05635 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ELJP9_RS05645 ENOG4105HEI LysR family (Transcriptional regulator ELJP9_RS05650 ENOG4105CHR reductase ELJP9_RS05660 ENOG4105CHJ isochorismatase hydrolase ELJP9_RS05670 ENOG4107VGR Catalase ELJP9_RS05700 ENOG4105KD7 acetyltransferase ELJP9_RS05750 ENOG4105C7K acetolactate synthase ELJP9_RS05755 ENOG4105CHR reductase ELJP9_RS05785 ENOG4105C94 Transporter ELJP9_RS05800 ENOG4108TSE Transferase ELJP9_RS05805 ENOG4107RNH Outer membrane receptor FepA ELJP9_RS05810 ENOG4105E93 esterase ELJP9_RS05815 ENOG41085A6 mbth domain-containing protein ELJP9_RS05825 ENOG4105E0A ABC, transporter ELJP9_RS05830 ENOG4105TVJ transport system, permease ELJP9_RS05835 ENOG4105DQ5 transport system permease protein ELJP9_RS05845 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein ELJP9_RS05855 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ELJP9_RS05860 ENOG4105WQI isochorismatase ELJP9_RS05865 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ELJP9_RS05870 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) ELJP9_RS05875 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) ELJP9_RS05880 ENOG4108P2H Inner membrane protein YjiG ELJP9_RS05885 ENOG41074DU domain protein ELJP9_RS05890 ENOG4105D22 carbon starvation protein ELJP9_RS05895 ENOG4105VCD cytoplasmic protein ELJP9_RS05900 ENOG4105CHR reductase ELJP9_RS05905 ENOG4107SCQ Iron-containing alcohol dehydrogenase ELJP9_RS05910 ENOG4105C2J ABC transporter ELJP9_RS05915 ENOG4105CNN ABC, transporter ELJP9_RS05930 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) ELJP9_RS05935 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) ELJP9_RS05945 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) ELJP9_RS05950 ENOG4106YVY Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity) ELJP9_RS05955 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) ELJP9_RS05960 ENOG4105CHM Aminotransferase ELJP9_RS05965 ENOG4105DQS Transcriptional regulator ELJP9_RS05970 ENOG4105D3R alkyl hydroperoxide reductase ELJP9_RS05975 ENOG4108JU3 Alkyl hydroperoxide reductase ELJP9_RS05980 ENOG4108U51 Universal stress protein ELJP9_RS05985 ENOG4105E2A Dehydrogenase ELJP9_RS05990 ENOG4105NXH GreA GreB family elongation factor ELJP9_RS06005 ENOG4105KTS ribonuclease ELJP9_RS06010 ENOG4105CEE C4-dicarboxylate transporter ELJP9_RS06015 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) ELJP9_RS06025 ENOG4107Z6W Protein CrcB homolog ELJP9_RS06035 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) ELJP9_RS06040 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) ELJP9_RS06050 ENOG41064T2 transcriptional regulator, lysR family ELJP9_RS06055 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) ELJP9_RS06060 ENOG4108Z43 UPF0250 protein ELJP9_RS06065 ENOG4105DZ1 carboxypeptidase ELJP9_RS06070 ENOG4105K6T rare lipoprotein A ELJP9_RS06075 ENOG4105CNI cell division protein FtsW ELJP9_RS06080 ENOG4105CJN penicillin-binding protein ELJP9_RS06085 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) ELJP9_RS06090 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) ELJP9_RS06100 ENOG4105DJF DNA polymerase III, delta' subunit ELJP9_RS06110 ENOG4105C8T Leucyl-tRNA synthetase ELJP9_RS06115 ENOG4107PAI alpha helical protein ELJP9_RS06120 ENOG4105DU0 nucleoside hydrolase ELJP9_RS06125 ENOG4105CDA abc transporter atp-binding protein ELJP9_RS06130 ENOG4105DRP amino acid AbC transporter ELJP9_RS06135 ENOG4105EAD ABC transporter ELJP9_RS06140 ENOG4107RP9 extracellular solute-binding protein, family 3 ELJP9_RS06145 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) ELJP9_RS06150 ENOG4108JU5 Magnesium and cobalt efflux protein ELJP9_RS06155 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) ELJP9_RS06160 ENOG4105C9A Phoh family ELJP9_RS06170 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ELJP9_RS06210 ENOG4105CAQ asparagine synthetase ELJP9_RS06215 ENOG4105D4U had-superfamily hydrolase, subfamily iia ELJP9_RS06220 ENOG4105E2R ROK family ELJP9_RS06225 ENOG4105CE4 GlcNAc 6-P deacetylase ELJP9_RS06235 ENOG4105CI1 PTS System ELJP9_RS06240 ENOG4105CX6 glutaminyL-tRNA synthetase ELJP9_RS06250 ENOG4105GX6 (LipO)protein ELJP9_RS06255 ENOG41090R7 Ferric uptake ELJP9_RS06260 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) ELJP9_RS06265 ENOG4105NNH LexA regulated protein ELJP9_RS06270 ENOG4105EV9 Alpha Beta Hydrolase ELJP9_RS06275 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) ELJP9_RS06280 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 ELJP9_RS06285 ENOG4105D5Q Arginine ornithine antiporter ELJP9_RS06290 ENOG4105CXN decarboxylase ELJP9_RS06300 ENOG4105EEX Two component transcriptional regulator (Winged helix family ELJP9_RS06305 ENOG4105C08 Histidine kinase ELJP9_RS06310 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) ELJP9_RS06315 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ELJP9_RS06320 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) ELJP9_RS06330 ENOG4105XIQ Protein of unknown function (DUF2517) ELJP9_RS06335 ENOG4105CVP deoxyribo-dipyrimidine photolyase ELJP9_RS06345 ENOG4105P4J Allophanate hydrolase, subunit 1 ELJP9_RS06350 ENOG4107R7A Allophanate hydrolase subunit 2 ELJP9_RS06360 ENOG4108S0J Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity) ELJP9_RS06365 ENOG4105BZN citrate synthase ELJP9_RS06370 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit ELJP9_RS06375 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein ELJP9_RS06380 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) ELJP9_RS06385 ENOG4105E33 succinate dehydrogenase ELJP9_RS06390 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 ELJP9_RS06405 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ELJP9_RS06410 ENOG4105FDP GntR family transcriptional regulator ELJP9_RS06415 ENOG4105DM4 PTS System ELJP9_RS06420 ENOG4105C8I hydrolase, family 38 ELJP9_RS06425 ENOG4105C4M (Ubiquinol oxidase) subunit I ELJP9_RS06430 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ELJP9_RS06440 ENOG4105KJB cyd operon protein YbgE ELJP9_RS06445 ENOG4107YD3 Thioesterase ELJP9_RS06450 ENOG4105E02 MotA TolQ exbB proton channel ELJP9_RS06460 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA ELJP9_RS06470 ENOG4105KCK Peptidoglycan-associated lipoprotein ELJP9_RS06475 ENOG4105UFD tol-pal system protein YbgF ELJP9_RS06510 ENOG4106Z1T Nicotinamide Mononucleotide Transporter ELJP9_RS06515 ENOG4105PGM cation diffusion facilitator family transporter ELJP9_RS06520 ENOG4105JND homeobox protein ELJP9_RS06525 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ELJP9_RS06530 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ELJP9_RS06535 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) ELJP9_RS06540 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) ELJP9_RS06545 ENOG4105F0Z galactose-1-phosphate uridylyltransferase ELJP9_RS06550 ENOG4105CMR udp-glucose 4-epimerase ELJP9_RS06555 ENOG4105DKW ABC transporter ELJP9_RS06560 ENOG4105F4R Transcriptional regulator mode ELJP9_RS06575 ENOG4105E0C molybdate abc transporter ELJP9_RS06585 ENOG4108K4B hydrolase ELJP9_RS06590 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) ELJP9_RS06595 ENOG4105NBR Pectinesterase ELJP9_RS06600 ENOG4105CI2 imidazolone-5-propionate hydrolase ELJP9_RS06605 ENOG41088SP formiminoglutamate hydrolase ELJP9_RS06615 ENOG4105CGP Urocanate hydratase ELJP9_RS06620 ENOG4105C84 Histidine ammonia-lyase ELJP9_RS06625 ENOG4108V1U phospholipid-binding protein ELJP9_RS06630 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ELJP9_RS06635 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) ELJP9_RS06640 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) ELJP9_RS06645 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ELJP9_RS06655 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS06665 ENOG4105CHW UPF0052 protein ELJP9_RS06675 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ELJP9_RS06680 ENOG4108RIR Molybdenum cofactor biosynthesis protein ELJP9_RS06685 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ELJP9_RS06690 ENOG4105M00 molybdopterin converting factor, subunit 1 ELJP9_RS06695 ENOG4108ZAF Molybdopterin ELJP9_RS06700 ENOG4105HFZ Membrane ELJP9_RS06705 ENOG4107UXM Membrane ELJP9_RS06710 ENOG4105DZQ phospholipase D Transphosphatidylase ELJP9_RS06715 ENOG4105X23 Endonuclease Exonuclease phosphatase ELJP9_RS06720 ENOG4105I9U inner membrane protein ybhQ ELJP9_RS06725 ENOG4107QWP ABC-2 type transporter ELJP9_RS06730 ENOG4107QWP ABC-2 type transporter ELJP9_RS06735 ENOG4105CJ1 ABC, transporter ELJP9_RS06740 ENOG4105D0S secretion protein (HlyD ELJP9_RS06745 ENOG4107MVR Transcriptional regulator ELJP9_RS06755 ENOG4105DVT helicase ELJP9_RS06775 ENOG4108VCD Chaperone ELJP9_RS06780 ENOG4105MX3 Fimbrial ELJP9_RS06785 ENOG4108MTB glycosyl transferase family ELJP9_RS06795 ENOG4105KSC Transcriptional regulator, TraR DksA family ELJP9_RS06800 ENOG4105ZY9 UPF0379 protein ybiM ELJP9_RS06805 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) ELJP9_RS06810 ENOG4105D8X mechanosensitive ion channel ELJP9_RS06815 ENOG4105CDA abc transporter atp-binding protein ELJP9_RS06820 ENOG4105E5Q amino acid AbC transporter ELJP9_RS06825 ENOG4107R0W ABC transporter ELJP9_RS06835 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction ELJP9_RS06845 ENOG4108T1M outer membrane protein x ELJP9_RS06850 ENOG4108I6E Sulfatase ELJP9_RS06860 ENOG4105KST dependent repressor ELJP9_RS06865 ENOG4105F4P )-transporter ELJP9_RS06870 ENOG4105CW7 secretion protein, HlyD family ELJP9_RS06875 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS06885 ENOG4105CPC Aldo Keto reductase ELJP9_RS06890 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS06895 ENOG4105CK1 PTS System ELJP9_RS06900 ENOG4105FDP GntR family transcriptional regulator ELJP9_RS06905 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ELJP9_RS06910 ENOG4105C5H ABC transporter ELJP9_RS06920 ENOG4105DPW Major facilitator superfamily MFS_1 ELJP9_RS06925 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS06930 ENOG41072TH Protein of unknown function (DUF1479) ELJP9_RS06935 ENOG4108HCJ Hydrolase ELJP9_RS06945 ENOG4105F1A Pyruvate formate-lyase ELJP9_RS06950 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ELJP9_RS06955 ENOG4105D06 uba thif-type nad fad binding protein ELJP9_RS06960 ENOG4105CVM Molybdenum cofactor synthesis domain protein ELJP9_RS06965 ENOG4105D44 asparaginase ELJP9_RS06970 ENOG4108JQ6 ABC transporter ELJP9_RS06980 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ELJP9_RS06990 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) ELJP9_RS06995 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway ELJP9_RS07000 ENOG4105D8V Glucose sorbosone dehydrogenase ELJP9_RS07005 ENOG4108TGY Glutathione S-transferase ELJP9_RS07010 ENOG4105DZ1 carboxypeptidase ELJP9_RS07015 ENOG4107FB0 transcriptional regulator DeoR family ELJP9_RS07020 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ELJP9_RS07030 ENOG4107QF7 multi-drug ELJP9_RS07035 ENOG4108HCJ Hydrolase ELJP9_RS07040 ENOG4106UW1 Major Facilitator superfamily ELJP9_RS07045 ENOG4108RFG Tetr family transcriptional regulator ELJP9_RS07050 ENOG4105CHR reductase ELJP9_RS07075 ENOG4105GWF inner membrane protein YbjM ELJP9_RS07080 ENOG41090BQ Glutaredoxin ELJP9_RS07085 ENOG4108DBC nitroreductase ELJP9_RS07090 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) ELJP9_RS07095 ENOG4108RMJ sensory transduction regulator ELJP9_RS07105 ENOG4107RUE extracellular solute-binding protein family 1 ELJP9_RS07110 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS07115 ENOG4105F38 ABC transporter, permease ELJP9_RS07120 ENOG4105D38 putrescine abc transporter ELJP9_RS07125 ENOG4105RBQ inner membrane protein ybjO ELJP9_RS07130 ENOG4107SFS Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity) ELJP9_RS07135 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ELJP9_RS07140 ENOG4105BZU Histidine kinase ELJP9_RS07145 ENOG4106TNF Periplasmic binding protein ELJP9_RS07150 ENOG4105DMR ABC, transporter ELJP9_RS07155 ENOG4105GBT ABC transporter ELJP9_RS07160 ENOG4106PMH Extracellular solute-binding protein family 3 ELJP9_RS07165 ENOG4105E5Z arginine transporter ATP-binding subunit ELJP9_RS07170 ENOG41064MM (LipO)protein ELJP9_RS07175 ENOG4105K8R UPF0145 protein ELJP9_RS07180 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase ELJP9_RS07185 ENOG4108PNB DNA-binding transcriptional regulator ELJP9_RS07200 ENOG4108XKW General secretion pathway protein C ELJP9_RS07205 ENOG4105GVR general secretion pathway protein D ELJP9_RS07210 ENOG4107QHF type ii secretion system protein e ELJP9_RS07215 ENOG4105D7Q type ii secretion system ELJP9_RS07220 ENOG4108VAU general secretion pathway protein G ELJP9_RS07230 ENOG4105X5Z General secretion pathway protein I ELJP9_RS07275 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase ELJP9_RS07280 ENOG4105CGD Nad-dependent epimerase dehydratase ELJP9_RS07285 ENOG4105C5W Aldolase ELJP9_RS07290 ENOG4105C7K acetolactate synthase ELJP9_RS07300 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ELJP9_RS07305 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) ELJP9_RS07310 ENOG4105DWU Membrane ELJP9_RS07315 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ELJP9_RS07320 ENOG4105CPB ATP-dependent endonuclease of the OLD family ELJP9_RS07330 ENOG4105DJY efflux transporter, rnd family, mfp subunit ELJP9_RS07340 ENOG4105VEQ Cold shock protein ELJP9_RS07345 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) ELJP9_RS07350 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ELJP9_RS07365 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) ELJP9_RS07370 ENOG4108JJ8 (ABC) transporter ELJP9_RS07375 ENOG4108JJ9 ABC, transporter ELJP9_RS07390 ENOG4105EW9 transcriptional regulator AsnC family ELJP9_RS07395 ENOG4105CNU cell division protein FtsK ELJP9_RS07400 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) ELJP9_RS07405 ENOG4105D1H recombination factor protein RarA ELJP9_RS07410 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) ELJP9_RS07415 ENOG4107QY8 reductase ELJP9_RS07420 ENOG4105QAX Iron-sulfur ELJP9_RS07425 ENOG4107KGK dmso reductase anchor subunit ELJP9_RS07445 ENOG4105F1A Pyruvate formate-lyase ELJP9_RS07450 ENOG4105C6N Formate acetyltransferase ELJP9_RS07455 ENOG4105TMB Formate nitrite transporter ELJP9_RS07460 ENOG4105DDY UPF0142 protein ycaO ELJP9_RS07465 ENOG4107VMU Membrane ELJP9_RS07470 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) ELJP9_RS07475 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase ELJP9_RS07480 ENOG4105CAT Cytidine monophosphate kinase ELJP9_RS07485 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) ELJP9_RS07490 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) ELJP9_RS07495 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 ELJP9_RS07500 ENOG4105BZ1 (ABC) transporter ELJP9_RS07505 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) ELJP9_RS07510 ENOG4105T0Z Conserved Protein ELJP9_RS07515 ENOG4105W49 UPF0434 protein ELJP9_RS07520 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) ELJP9_RS07525 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups ELJP9_RS07530 ENOG4107S90 membrAne ELJP9_RS07545 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) ELJP9_RS07550 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) ELJP9_RS07555 ENOG4105DIT ErfK YbiS YcfS YnhG family protein ELJP9_RS07560 ENOG4105EAQ (twin-arginine translocation) pathway signal ELJP9_RS07565 ENOG4105C5X domain protein ELJP9_RS07570 ENOG4105CGF Aromatic amino acid aminotransferase ELJP9_RS07575 ENOG4105FCK Membrane ELJP9_RS07580 ENOG4105C5S asparaginyl-tRNA synthetase ELJP9_RS07585 ENOG4107RH7 Nicotinate phosphoribosyltransferase ELJP9_RS07590 ENOG4105CD8 aminopeptidase N ELJP9_RS07600 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ELJP9_RS07605 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) ELJP9_RS07610 ENOG4105GVF (ABC) transporter ELJP9_RS07615 ENOG4108UZX fmn reductase ELJP9_RS07620 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) ELJP9_RS07625 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) ELJP9_RS07630 ENOG4105QVC MOSC domain-containing protein ELJP9_RS07635 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) ELJP9_RS07640 ENOG4105C5H ABC transporter ELJP9_RS07645 ENOG4105F1S paraquat-inducible protein a ELJP9_RS07650 ENOG4105DY2 Paraquat-inducible protein b ELJP9_RS07655 ENOG4108Q2G (LipO)protein ELJP9_RS07660 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) ELJP9_RS07670 ENOG4105DAN ATP-dependent protease ELJP9_RS07675 ENOG4108R9Q Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity) ELJP9_RS07680 ENOG4105UYK outer membrane protein a ELJP9_RS07685 ENOG4108ZD2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity) ELJP9_RS07690 ENOG4108RZ1 DNA transformation protein ELJP9_RS07695 ENOG4105EM2 membrane ELJP9_RS07700 ENOG410901E Membrane ELJP9_RS07705 ENOG41088T4 Helicase IV ELJP9_RS07710 ENOG4108Z5K methylglyoxal synthase ELJP9_RS07715 ENOG4108Q67 UPF0319 protein ELJP9_RS07720 ENOG4105K4P CoA-binding domain protein ELJP9_RS07725 ENOG4105GSS Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity) ELJP9_RS07730 ENOG4105DR4 Methyltransferase ELJP9_RS07735 ENOG4108V1U phospholipid-binding protein ELJP9_RS07745 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 ELJP9_RS07750 ENOG4108Z0T Part of a sulfur-relay system (By similarity) ELJP9_RS07755 ENOG4108MN8 Membrane ELJP9_RS07765 ENOG4107QSI ABC, transporter ELJP9_RS07805 ENOG4108ZG0 Ompa motb domain protein ELJP9_RS07815 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ELJP9_RS07820 ENOG4105CS6 Rhs element vgr protein ELJP9_RS07930 ENOG41061H0 Monooxygenase ELJP9_RS07940 ENOG41084YZ Hydrolase ELJP9_RS07945 ENOG4107QUY Guanine deaminase ELJP9_RS07950 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease ELJP9_RS07985 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ELJP9_RS08005 ENOG4105E5Q amino acid AbC transporter ELJP9_RS08015 ENOG4105C5R Aminotransferase ELJP9_RS08030 ENOG4107FKK extracellular solute-binding protein family 1 ELJP9_RS08040 ENOG4105EG2 ABC transporter, permease ELJP9_RS08050 ENOG4105C4C beta-galactosidase ELJP9_RS08055 ENOG4105CI1 PTS System ELJP9_RS08060 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) ELJP9_RS08065 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS08070 ENOG4105CJW magnesium transporter ELJP9_RS08075 ENOG4107T5V SNARE associated Golgi ELJP9_RS08080 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr ELJP9_RS08090 ENOG4105D6F Phosphatase ELJP9_RS08095 ENOG4105XH3 ELJP9_RS08100 ENOG4105CS1 NAD(P)H quinone oxidoreductase ELJP9_RS08105 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 ELJP9_RS08115 ENOG4105C2W permease ELJP9_RS08120 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) ELJP9_RS08125 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) ELJP9_RS08130 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) ELJP9_RS08135 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) ELJP9_RS08140 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) ELJP9_RS08145 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) ELJP9_RS08150 ENOG4108R86 Transcriptional regulator ELJP9_RS08160 ENOG4105C26 Dehydrogenase ELJP9_RS08165 ENOG4105CK7 Sodium proline symporter ELJP9_RS08175 ENOG4105D9N nucleoside ELJP9_RS08190 ENOG410650H (LipO)protein ELJP9_RS08200 ENOG4105D5M phosphate starvation-inducible protein ELJP9_RS08210 ENOG4105CHJ isochorismatase hydrolase ELJP9_RS08215 ENOG4105EUB pirin domain protein ELJP9_RS08220 ENOG4105CC0 LysR family Transcriptional regulator ELJP9_RS08235 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase ELJP9_RS08240 ENOG4107SSZ Phosphatase ELJP9_RS08245 ENOG4107XHZ cytoplasmic chaperone TorD family protein ELJP9_RS08250 ENOG4108UQ5 membrane protein YcdZ ELJP9_RS08255 ENOG4105P8Q Curli production assembly transport component CsgG ELJP9_RS08260 ENOG4108WYR Curli production assembly transport component, CsgF ELJP9_RS08265 ENOG4108XDW curli assembly protein CsgE ELJP9_RS08270 ENOG41086KC Transcriptional regulator ELJP9_RS08280 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin ELJP9_RS08285 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) ELJP9_RS08290 ENOG41068SS ELJP9_RS08295 ENOG4108UVJ appr-1-p processing domain protein ELJP9_RS08310 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) ELJP9_RS08315 ENOG4105NAC (LipO)protein ELJP9_RS08320 ENOG4108W47 Acidic protein msyB ELJP9_RS08325 ENOG4105C6X Major Facilitator ELJP9_RS08330 ENOG4105D1S lipid A biosynthesis ELJP9_RS08335 ENOG4105C72 UPF0176 protein ELJP9_RS08340 ENOG4108YYC ycei family ELJP9_RS08345 ENOG4105DS1 cytochrome b561 ELJP9_RS08350 ENOG4106974 biofilm formation ELJP9_RS08355 ENOG4105F76 Sarcosine oxidase ELJP9_RS08360 ENOG4105PVA Biofilm formation regulatory protein BssS ELJP9_RS08365 ENOG4105MEA DNA damage-inducible protein i ELJP9_RS08370 ENOG4105EKE dihydroorotase ELJP9_RS08375 ENOG4105F3T (LipO)protein ELJP9_RS08380 ENOG4105EV4 Multidrug resistance protein mdtH ELJP9_RS08385 ENOG4105D9U N-acetyltransferase ELJP9_RS08390 ENOG4108YXG UPF0502 protein ELJP9_RS08395 ENOG4105EP9 oxidoreductase ELJP9_RS08400 ENOG4105CJR Integral membrane protein (MviN ELJP9_RS08405 ENOG4105QVD Flagella synthesis protein FlgN ELJP9_RS08410 ENOG4105M9M anti-sigma28 factor FlgM ELJP9_RS08415 ENOG4105CKS Flagella basal body P-ring formation protein flgA ELJP9_RS08420 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) ELJP9_RS08425 ENOG4108ZC9 flagellar basal-body rod protein flgc ELJP9_RS08430 ENOG4105W00 Flagellar hook capping protein ELJP9_RS08435 ENOG4105BZE flagellar hook protein, FlgE ELJP9_RS08440 ENOG4108KPB Flagellar basal-body rod protein FlgF ELJP9_RS08445 ENOG4105CGA flagellar basal-body rod protein FlgG ELJP9_RS08460 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj ELJP9_RS08465 ENOG4105E1Q flagellar hook-associated protein ELJP9_RS08470 ENOG4105DTJ flagellar hook-associated protein ELJP9_RS08475 ENOG4105EQ0 Major Facilitator superfamily ELJP9_RS08480 ENOG4105EJC lysr family transcriptional regulator ELJP9_RS08485 ENOG4107QQB Ribonuclease E ELJP9_RS08490 ENOG4105EI2 Pseudouridine synthase ELJP9_RS08500 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein ELJP9_RS08505 ENOG4105VGS 50s ribosomal protein l32 ELJP9_RS08510 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) ELJP9_RS08515 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) ELJP9_RS08520 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ELJP9_RS08530 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) ELJP9_RS08535 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ELJP9_RS08540 ENOG4105YAZ 4-amino-4-deoxychorismate lyase ELJP9_RS08545 ENOG4105HHA aminodeoxychorismate lyase ELJP9_RS08550 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) ELJP9_RS08555 ENOG4107QRG dna polymerase iii ELJP9_RS08560 ENOG4105F8V Hydrolase, tatD family ELJP9_RS08565 ENOG4105CI1 PTS System ELJP9_RS08570 ENOG4105CNM Receptor ELJP9_RS08575 ENOG4105K59 histidine triad (HIT) protein ELJP9_RS08580 ENOG41090DQ Lipoprotein ELJP9_RS08585 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) ELJP9_RS08600 ENOG4105D0Y UPF0227 protein ELJP9_RS08605 ENOG4105CEP NADH dehydrogenase ELJP9_RS08610 ENOG4107MBR 17 kDa surface antigen ELJP9_RS08615 ENOG4108IND Tetr family transcriptional regulator ELJP9_RS08620 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction ELJP9_RS08625 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ELJP9_RS08635 ENOG4105IQC Inner membrane protein YcfT ELJP9_RS08640 ENOG4105D60 lipoprotein releasing system transmembrane protein ELJP9_RS08645 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) ELJP9_RS08650 ENOG4105D60 lipoprotein releasing system transmembrane protein ELJP9_RS08655 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) ELJP9_RS08660 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ELJP9_RS08665 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS08670 ENOG4105D58 Diguanylate phosphodiesterase ELJP9_RS08675 ENOG4108HM4 ABC transporter ELJP9_RS08680 ENOG4108EG7 Binding-protein-dependent transport systems, inner membrane component ELJP9_RS08700 ENOG4105EZE Cupin 4 family protein ELJP9_RS08710 ENOG4105XJC Two component transcriptional regulator (Winged helix family ELJP9_RS08715 ENOG4107QTF adenylosuccinate lyase ELJP9_RS08720 ENOG41075W9 High frequency lysogenization protein HflD homolog ELJP9_RS08735 ENOG4108R99 pseudouridine synthase ELJP9_RS08740 ENOG4108HMX isocitrate dehydrogenase (NADP) ELJP9_RS08745 ENOG4105D3P Mannan endo-1,4-beta-mannosidase ELJP9_RS08755 ENOG4105N0E Protein of unknown function (DUF2543) ELJP9_RS08770 ENOG4105BZU Histidine kinase ELJP9_RS08780 ENOG4105Y3U Transglycosylase-associated protein ELJP9_RS08790 ENOG4106G4W ELJP9_RS08795 ENOG410620I Diguanylate cyclase ELJP9_RS08800 ENOG4105UCG Domain of unknown function (DUF333) ELJP9_RS08815 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) ELJP9_RS08820 ENOG4105DJ2 Major Facilitator Superfamily ELJP9_RS08825 ENOG4105R1U AraC Family Transcriptional Regulator ELJP9_RS08830 ENOG4108VMM UPF0756 membrane protein ELJP9_RS08835 ENOG4108KXH Ybak prolyl-tRNA synthetase associated ELJP9_RS08845 ENOG4106AKX UPF0229 protein ELJP9_RS08855 ENOG4105GNX MltA-interacting MipA family protein ELJP9_RS08860 ENOG4105CV8 reductase ELJP9_RS08865 ENOG4105DSB aldose 1-epimerase ELJP9_RS08870 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ELJP9_RS08880 ENOG4105VUT cytoplasmic protein ELJP9_RS08890 ENOG4108RWI nicotinamidase ELJP9_RS08895 ENOG4105HDK L-asparaginase ELJP9_RS08900 ENOG4105D07 Signal peptide peptidase, SppA ELJP9_RS08905 ENOG41069NU Nitroreductase ELJP9_RS08910 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) ELJP9_RS08915 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ELJP9_RS08920 ENOG4105D82 Glutamate dehydrogenase ELJP9_RS08925 ENOG4105MTM Protein of unknown function (DUF1496) ELJP9_RS08935 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) ELJP9_RS08940 ENOG4108T9J Cdp-alcohol phosphatidyltransferase ELJP9_RS08945 ENOG4107RM6 sulfurtransferase ELJP9_RS08950 ENOG4108VGW abc transporter atp-binding protein ELJP9_RS08955 ENOG4105CXZ ABC transporter, permease ELJP9_RS08960 ENOG4105VNH ABC transporter solute-binding protein ELJP9_RS08970 ENOG4105CGK Exodeoxyribonuclease III ELJP9_RS08975 ENOG4105C8Y Acetylornithine aminotransferase ELJP9_RS08980 ENOG4105F4X arginine ELJP9_RS08985 ENOG4105C26 Dehydrogenase ELJP9_RS08990 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) ELJP9_RS09000 ENOG4108SPG Periplasmic Protein ELJP9_RS09005 ENOG41090B9 response to stress ELJP9_RS09010 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) ELJP9_RS09015 ENOG4107RA1 nh(3)-dependent nad( ) synthetase ELJP9_RS09020 ENOG4105KKI DNA-binding transcriptional activator OsmE ELJP9_RS09025 ENOG4105VZJ PTS System ELJP9_RS09030 ENOG4105CK1 PTS System ELJP9_RS09035 ENOG4105VCP PTS System ELJP9_RS09040 ENOG4105EZV Transcriptional regulator ELJP9_RS09045 ENOG4105F8D glycoside hydrolase family 4 ELJP9_RS09050 ENOG410901P UPF0249 protein ELJP9_RS09055 ENOG4105CH6 catalase ELJP9_RS09060 ENOG4105R8J Activates the cell division inhibited by chromosomal DNA over-replication (By similarity) ELJP9_RS09065 ENOG4108ETY sodium dicarboxylate symporter ELJP9_RS09070 ENOG4107K5X Membrane-bound metal-dependent hydrolase ELJP9_RS09075 ENOG4105CHR reductase ELJP9_RS09080 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 ELJP9_RS09085 ENOG4107PN8 YfeABCD locus regulator ELJP9_RS09095 ENOG4105P10 Uncharacterized protein ydiZ ELJP9_RS09100 ENOG4105DE4 1-phosphofructokinase ELJP9_RS09105 ENOG4108NE3 Salt-induced outer membrane protein ELJP9_RS09110 ENOG4105VR4 UPF0379 protein ybiJ ELJP9_RS09130 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) ELJP9_RS09135 ENOG41082NX 50s ribosomal protein l35 ELJP9_RS09150 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) ELJP9_RS09160 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) ELJP9_RS09170 ENOG4108V06 Glutathione peroxidase ELJP9_RS09175 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS09180 ENOG4108QBX (LipO)protein ELJP9_RS09185 ENOG4108TC0 Diguanylate phosphodiesterase ELJP9_RS09190 ENOG4105CNG UPF0061 protein ELJP9_RS09195 ENOG4105DTD Dehydrogenase ELJP9_RS09205 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS09215 ENOG4107QP7 CoA-transferase subunit A ELJP9_RS09220 ENOG4106NZI LysR family Transcriptional regulator ELJP9_RS09225 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS09230 ENOG4105EHG Permease protein ELJP9_RS09235 ENOG4107R4I Periplasmic binding protein ELJP9_RS09240 ENOG4106QJH hemin transport protein ELJP9_RS09245 ENOG4107ENK receptor ELJP9_RS09255 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ELJP9_RS09260 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) ELJP9_RS09265 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) ELJP9_RS09275 ENOG4107QK4 glycoside hydrolase, family 3 domain protein ELJP9_RS09285 ENOG4105IPI Membrane ELJP9_RS09290 ENOG4105CQB FAD linked oxidase domain protein ELJP9_RS09295 ENOG4105KA0 thioesterase Superfamily protein ELJP9_RS09300 ENOG410671Z uncharacterized protein ydiH ELJP9_RS09305 ENOG4108PNB DNA-binding transcriptional regulator ELJP9_RS09310 ENOG4108PNB DNA-binding transcriptional regulator ELJP9_RS09315 ENOG4108RQP Major type 1 subunit fimbrin ELJP9_RS09320 ENOG4108VCD Chaperone ELJP9_RS09325 ENOG4105CW0 outer membrane usher protein ELJP9_RS09345 ENOG4108C80 FliB family ELJP9_RS09350 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) ELJP9_RS09365 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component ELJP9_RS09370 ENOG4105BZU Histidine kinase ELJP9_RS09375 ENOG4108XDN Transcriptional regulator ELJP9_RS09380 ENOG4108Z4V iron-sulfur cluster assembly ELJP9_RS09385 ENOG4105DIW FeS assembly protein SUFB ELJP9_RS09390 ENOG4105C3K feS assembly ATPase SufC ELJP9_RS09395 ENOG4105JRK feS assembly protein SufD ELJP9_RS09400 ENOG4105C9B Cysteine desulfurase ELJP9_RS09405 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) ELJP9_RS09410 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ELJP9_RS09420 ENOG4105CA9 Pyruvate kinase ELJP9_RS09425 ENOG4105C28 cystathionine ELJP9_RS09445 ENOG4105D01 (LipO)protein ELJP9_RS09450 ENOG4105RFR Protein of unknown function (DUF2767) ELJP9_RS09455 ENOG4105DRP amino acid AbC transporter ELJP9_RS09460 ENOG4105E5Q amino acid AbC transporter ELJP9_RS09470 ENOG4105CT1 (ABC) transporter ELJP9_RS09475 ENOG4105BZU Histidine kinase ELJP9_RS09480 ENOG4108ZXC Two component transcriptional regulator, luxr family ELJP9_RS09500 ENOG4107B2H carbonic anhydrase ELJP9_RS09505 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain ELJP9_RS09520 ENOG4107QI1 Mate efflux family protein ELJP9_RS09525 ENOG4108R6K riboflavin synthase, subunit alpha ELJP9_RS09535 ENOG4105CZQ inner membrane transport protein YdhC ELJP9_RS09540 ENOG4105F52 Transcriptional regulator ELJP9_RS09555 ENOG4105F27 Major Facilitator ELJP9_RS09560 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ELJP9_RS09565 ENOG4105K4H Nlp p60 protein ELJP9_RS09570 ENOG4105M2J Glutaredoxin ELJP9_RS09575 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) ELJP9_RS09580 ENOG4108UYE Lactoylglutathione lyase ELJP9_RS09585 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ELJP9_RS09590 ENOG4108WUH Transcriptional regulator, TetR family ELJP9_RS09595 ENOG4105DIJ Phosphoethanolamine transferase ELJP9_RS09600 ENOG4105XZD Fe-S protein ELJP9_RS09605 ENOG4107RGM aldo keto reductase ELJP9_RS09610 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ELJP9_RS09615 ENOG4105DSW Fusaric acid resistance protein ELJP9_RS09620 ENOG4105Y49 secretion protein, HlyD family ELJP9_RS09635 ENOG4105BZU Histidine kinase ELJP9_RS09640 ENOG4108XTF Outer Membrane Lipoprotein ELJP9_RS09645 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) ELJP9_RS09650 ENOG410642K Lysozyme inhibitor ELJP9_RS09655 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) ELJP9_RS09660 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ELJP9_RS09665 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) ELJP9_RS09670 ENOG4108K3A Glutathione S-transferase ELJP9_RS09675 ENOG4105DUX Transporter ELJP9_RS09680 ENOG4105CSM endonuclease III ELJP9_RS09685 ENOG4105DZB Electron transport complex ELJP9_RS09690 ENOG4108UQQ Electron transport complex ELJP9_RS09695 ENOG4105D6A Electron transport complex ELJP9_RS09710 ENOG4105DGN Electron transport complex ELJP9_RS09715 ENOG4105M9B inner membrane protein ydgK ELJP9_RS09725 ENOG4106C6R beta-lactam resistance protein ELJP9_RS09730 ENOG4105D9R oxidoreductase ELJP9_RS09735 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) ELJP9_RS09740 ENOG4105C87 Aminotransferase class I and II ELJP9_RS09745 ENOG4105CI1 PTS System ELJP9_RS09750 ENOG4107P2S Transcriptional regulator ELJP9_RS09755 ENOG4106J39 exported protein ELJP9_RS09760 ENOG4105EIP mannose-6-phosphate isomerase ELJP9_RS09765 ENOG4107GFK fumarate ELJP9_RS09770 ENOG4105C9Q fumarate hydratase class II ELJP9_RS09775 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) ELJP9_RS09780 ENOG4105JJR Histidine kinase ELJP9_RS09790 ENOG4107EXC regulatoR ELJP9_RS09795 ENOG4105RA2 Membrane ELJP9_RS09800 ENOG410642E Short chain dehydrogenase ELJP9_RS09805 ENOG4105D5Q Arginine ornithine antiporter ELJP9_RS09810 ENOG4105C5D exported protein ELJP9_RS09820 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ELJP9_RS09825 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) ELJP9_RS09830 ENOG4105Q9Y Universal stress protein ELJP9_RS09840 ENOG4105DS0 Transcriptional regulator, Crp Fnr family ELJP9_RS09845 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ELJP9_RS09850 ENOG4105CFC Transporter ELJP9_RS09855 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B ELJP9_RS09865 ENOG4106KR7 LysR family Transcriptional regulator ELJP9_RS09870 ENOG4108DG9 Smr protein MutS2 ELJP9_RS09875 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS09885 ENOG4105KT5 UmuD protein ELJP9_RS09890 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) ELJP9_RS09895 ENOG4105EJC lysr family transcriptional regulator ELJP9_RS09905 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ELJP9_RS09910 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase ELJP9_RS09920 ENOG4105N1F Hnh endonuclease ELJP9_RS09925 ENOG4108M8W Monooxygenase ELJP9_RS09930 ENOG4105DSF transport protein ELJP9_RS09935 ENOG41090TI Catalyzes the excretion of spermidine (By similarity) ELJP9_RS09940 ENOG4108ZBZ Catalyzes the excretion of spermidine (By similarity) ELJP9_RS09950 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap ELJP9_RS09960 ENOG4105CTD carboxy-peptidase ELJP9_RS09970 ENOG4105D94 Major Facilitator Superfamily ELJP9_RS09975 ENOG4106NZI LysR family Transcriptional regulator ELJP9_RS09980 ENOG4105DAG ROK family ELJP9_RS09985 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) ELJP9_RS09990 ENOG4105CMQ Chloride channel ELJP9_RS09995 ENOG4108IJ8 ABC transporter ELJP9_RS10000 ENOG4105E90 ABC transporter ELJP9_RS10005 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system ELJP9_RS10010 ENOG4108U0I binding-protein-dependent transport systems inner membrane Component ELJP9_RS10020 ENOG4108TGY Glutathione S-transferase ELJP9_RS10045 ENOG4105D7T ABC transporter ELJP9_RS10050 ENOG4105EIG urea carboxylase-associated protein 1 ELJP9_RS10055 ENOG4105EIG urea carboxylase-associated protein 1 ELJP9_RS10060 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ELJP9_RS10070 ENOG4108NEM leader-binding protein dmsD ELJP9_RS10075 ENOG4107KGK dmso reductase anchor subunit ELJP9_RS10080 ENOG4105QAX Iron-sulfur ELJP9_RS10085 ENOG4107QY8 reductase ELJP9_RS10090 ENOG4105KBG Protein of unknown function (DUF1161) ELJP9_RS10095 ENOG4108UY2 Chloramphenicol acetyltransferase ELJP9_RS10105 ENOG4108MK9 spermidine N(1)-acetyltransferase ELJP9_RS10110 ENOG4105M5Q UPF0482 protein ELJP9_RS10115 ENOG4105KK4 UPF0060 membrane protein ELJP9_RS10120 ENOG4105CXK mandelate racemase muconate lactonizing ELJP9_RS10125 ENOG4105CPQ Dehydrogenase ELJP9_RS10135 ENOG4105DEI Mannitol dehydrogenase ELJP9_RS10140 ENOG41061EV selenium-binding protein YdfZ ELJP9_RS10145 ENOG4108U51 Universal stress protein ELJP9_RS10150 ENOG4107XBN GntR Family Transcriptional Regulator ELJP9_RS10155 ENOG4105EMU Dehydrogenase ELJP9_RS10160 ENOG4105DGW oligopeptidase A ELJP9_RS10170 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase ELJP9_RS10185 ENOG4105EMU Dehydrogenase ELJP9_RS10205 ENOG4107QJH Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ELJP9_RS10230 ENOG4105C5I Dehydrogenase ELJP9_RS10245 ENOG4107H52 Dicarboxylate transport ELJP9_RS10250 ENOG410689M (LipO)protein ELJP9_RS10255 ENOG4105WXT Conserved Protein ELJP9_RS10260 ENOG4108WFR AraC Family Transcriptional Regulator ELJP9_RS10265 ENOG4105C26 Dehydrogenase ELJP9_RS10275 ENOG4105F11 amine oxidase ELJP9_RS10280 ENOG4105DXM phenylacetic acid degradation protein ELJP9_RS10285 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit ELJP9_RS10290 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit ELJP9_RS10295 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit ELJP9_RS10300 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit ELJP9_RS10305 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ELJP9_RS10310 ENOG4105E39 Enoyl-CoA hydratase ELJP9_RS10315 ENOG4108UKI Enoyl-CoA hydratase ELJP9_RS10320 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ELJP9_RS10325 ENOG4108ZJI phenylacetic acid degradation protein ELJP9_RS10330 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS10335 ENOG4105DZS Phenylacetate-CoA ligase ELJP9_RS10340 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein ELJP9_RS10345 ENOG4108Z0R Transferase ELJP9_RS10355 ENOG4105CBN LysR family transcriptional regulator ELJP9_RS10370 ENOG4105CBN LysR family transcriptional regulator ELJP9_RS10400 ENOG4105F04 LysR family Transcriptional regulator ELJP9_RS10405 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ELJP9_RS10445 ENOG4107FW0 short-chain dehydrogenase reductase ELJP9_RS10460 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase ELJP9_RS10495 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ELJP9_RS10505 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme ELJP9_RS10510 ENOG4105D3G Pseudouridine synthase ELJP9_RS10515 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) ELJP9_RS10520 ENOG4105CQ7 ATP-dependent helicase ELJP9_RS10530 ENOG4105ENJ RND efflux system, outer membrane lipoprotein ELJP9_RS10545 ENOG4107DB1 DUF218 domain ELJP9_RS10550 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ELJP9_RS10555 ENOG4105CPW cytochrome b561 ELJP9_RS10560 ENOG4105D9R oxidoreductase ELJP9_RS10565 ENOG4105E98 transcriptional regulator DeoR family ELJP9_RS10580 ENOG4108JJA ABC, transporter ELJP9_RS10605 ENOG4105WPN DNA integration recombination invertion protein ELJP9_RS10625 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS10630 ENOG4105DZG Dehydrogenase ELJP9_RS10635 ENOG4105DDW LysR family Transcriptional regulator ELJP9_RS10640 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ELJP9_RS10645 ENOG4108YDI single-species biofilm formation on inanimate substrate ELJP9_RS10655 ENOG4107VMU Membrane ELJP9_RS10660 ENOG4108WTK competence damage-inducible protein ELJP9_RS10675 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ELJP9_RS10680 ENOG4105C4M (Ubiquinol oxidase) subunit I ELJP9_RS10685 ENOG4105WEF catalase ELJP9_RS10690 ENOG4108N8X transition metal ion binding ELJP9_RS10700 ENOG4108Z9Z response to DNA damage stimulus ELJP9_RS10710 ENOG4105E32 cytoplasmic protein ELJP9_RS10715 ENOG4105EBR Carboxylesterase ELJP9_RS10725 ENOG4105CHM Aminotransferase ELJP9_RS10730 ENOG4105E89 ABC transporter ELJP9_RS10740 ENOG4108Z9I -acetyltransferase ELJP9_RS10745 ENOG4107WE3 acetyltransferase YdcK ELJP9_RS10750 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein ELJP9_RS10755 ENOG41088CC tellurite resistance protein tehB ELJP9_RS10760 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) ELJP9_RS10765 ENOG4105DEF Extracellular solute-binding protein, family 5 ELJP9_RS10770 ENOG4108KKZ (LipO)protein ELJP9_RS10775 ENOG4105DWP Membrane ELJP9_RS10780 ENOG4108DMH HTH_ARAC ELJP9_RS10785 ENOG4105DKK Benzoate ELJP9_RS10790 ENOG4108JCI Transcriptional regulator ELJP9_RS10795 ENOG4105CFP Peptidase U32 ELJP9_RS10800 ENOG4105RR0 Protein of unknown function (DUF2554) ELJP9_RS10830 ENOG4105C32 Amino acid ABC transporter (Permease) ELJP9_RS10835 ENOG4105CNN ABC, transporter ELJP9_RS10840 ENOG4105C0Z ABC transporter ELJP9_RS10845 ENOG4108IV0 ABC, transporter ELJP9_RS10850 ENOG4108MEK Metal-binding protein YodA ELJP9_RS10855 ENOG4105E5W Transporter ELJP9_RS10860 ENOG4108594 Permease of the drug metabolite transporter ELJP9_RS10865 ENOG4106DNR multiple antibiotic resistance protein ELJP9_RS10870 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF ELJP9_RS10875 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes ELJP9_RS10880 ENOG41082NP Multiple antibiotic resistance ELJP9_RS10885 ENOG4105F27 Major Facilitator ELJP9_RS10895 ENOG4105JAB phenazine biosynthesis protein, phzf family ELJP9_RS10915 ENOG4105EGI Transcriptional regulator ELJP9_RS10920 ENOG4105C26 Dehydrogenase ELJP9_RS10925 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS10935 ENOG4105CSV Glutaminase ELJP9_RS10940 ENOG4105M0C cytoplasmic protein ELJP9_RS10945 ENOG4105BZU Histidine kinase ELJP9_RS10950 ENOG4105BZU Histidine kinase ELJP9_RS10960 ENOG4107QZW Altronate oxidoreductase ELJP9_RS10965 ENOG4105FFC UPF0187 protein ELJP9_RS10975 ENOG4108Z24 l-2,4-diaminobutyric acid acetyltransferase ELJP9_RS10980 ENOG4105CPT Alpha beta hydrolase ELJP9_RS10990 ENOG4105E0F Histidine kinase ELJP9_RS11000 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) ELJP9_RS11005 ENOG4107VIJ nudix hydrolase ELJP9_RS11010 ENOG4105E98 transcriptional regulator DeoR family ELJP9_RS11040 ENOG4107R6D beta-lactam binding protein AmpH ELJP9_RS11060 ENOG410624V efflux system protein ELJP9_RS11070 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ELJP9_RS11085 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS11120 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) ELJP9_RS11130 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family ELJP9_RS11145 ENOG4107RSM transcriptional regulator ELJP9_RS11150 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) ELJP9_RS11155 ENOG4105VYA Uncharacterized conserved protein (DUF2132) ELJP9_RS11160 ENOG4105F32 YngK protein ELJP9_RS11165 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase ELJP9_RS11175 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) ELJP9_RS11200 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS11205 ENOG4105WBN Transcriptional regulator (LacI family ELJP9_RS11220 ENOG4108M0B Sucrose porin ELJP9_RS11225 ENOG4105D7K pfkb domain protein ELJP9_RS11230 ENOG4105BZU Histidine kinase ELJP9_RS11245 ENOG4108UQS dipeptidase ELJP9_RS11250 ENOG4105DEF Extracellular solute-binding protein, family 5 ELJP9_RS11255 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ELJP9_RS11260 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ELJP9_RS11265 ENOG4105C3U ABC transporter ELJP9_RS11270 ENOG4107H6U ABC transporter ELJP9_RS11275 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr ELJP9_RS11285 ENOG4108Z9K Osmotically inducible protein ELJP9_RS11295 ENOG4105EXG Transcriptional regulator ELJP9_RS11305 ENOG4105TPS biofilm-dependent modulation protein ELJP9_RS11315 ENOG4107R1I NAD-dependent malic enzyme ELJP9_RS11320 ENOG4105C5H ABC transporter ELJP9_RS11325 ENOG4105DQ4 alcohol dehydrogenase ELJP9_RS11340 ENOG4105F27 Major Facilitator ELJP9_RS11350 ENOG4108MG3 formate dehydrogenase ELJP9_RS11355 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ELJP9_RS11390 ENOG4107QND Nitrite extrusion protein ELJP9_RS11395 ENOG4105CRU nitrate reductase, alpha subunit ELJP9_RS11400 ENOG4108IUE nitrate reductase beta subunit ELJP9_RS11405 ENOG4108NZN Respiratory nitrate reductase 2 delta chain ELJP9_RS11410 ENOG4105D0D Nitrate reductase 2, gamma subunit ELJP9_RS11415 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase ELJP9_RS11420 ENOG4108MEJ flavin reductase domain protein ELJP9_RS11425 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) ELJP9_RS11430 ENOG4105YVS arsR family transcriptional regulator ELJP9_RS11435 ENOG4105KZK Tautomerase pptA ELJP9_RS11440 ENOG4108N27 Glutathione S-transferase ELJP9_RS11450 ENOG4105CDA abc transporter atp-binding protein ELJP9_RS11465 ENOG4105EAB amino acid AbC transporter ELJP9_RS11480 ENOG4105DEN Luciferase family ELJP9_RS11485 ENOG4105CAT Cytidine monophosphate kinase ELJP9_RS11490 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor ELJP9_RS11495 ENOG4105C85 amino acid ELJP9_RS11500 ENOG4108NS2 receptor ELJP9_RS11505 ENOG4105CHB tonB-dependent Receptor ELJP9_RS11510 ENOG4108WYP Transcriptional regulator ELJP9_RS11515 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein ELJP9_RS11520 ENOG4108IMY Transcriptional regulator ELJP9_RS11525 ENOG4108Z7F N-acetyltransferase ELJP9_RS11530 ENOG4108T9Y Inner membrane protein ydcZ ELJP9_RS11535 ENOG4105R71 cytoplasmic protein ELJP9_RS11540 ENOG4105DEF Extracellular solute-binding protein, family 5 ELJP9_RS11560 ENOG4108EMS branched-chain alpha-keto acid dehydrogenase subunit E2 ELJP9_RS11565 ENOG410654E Membrane ELJP9_RS11575 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component ELJP9_RS11580 ENOG4105D81 ABC transporter, permease ELJP9_RS11585 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS11590 ENOG4107TYH extracellular solute-binding protein family 1 ELJP9_RS11595 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ELJP9_RS11605 ENOG4105C4M (Ubiquinol oxidase) subunit I ELJP9_RS11610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ELJP9_RS11620 ENOG41090X5 Heat shock protein hslJ ELJP9_RS11625 ENOG4105IKK cytoplasmic protein ELJP9_RS11635 ENOG4105FCK Membrane ELJP9_RS11665 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) ELJP9_RS11670 ENOG4105C1J atp-dependent rna helicase ELJP9_RS11680 ENOG4107RX3 Mg2 transporter protein cora family protein ELJP9_RS11685 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS11690 ENOG4105BZU Histidine kinase ELJP9_RS11695 ENOG4105BZU Histidine kinase ELJP9_RS11700 ENOG4108Z0Z intracellular protease Pfpi family ELJP9_RS11710 ENOG4107QSI ABC, transporter ELJP9_RS11715 ENOG4105KXI murein peptide amidase A ELJP9_RS11720 ENOG4107S8C mandelate racemase muconate lactonizing ELJP9_RS11725 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) ELJP9_RS11735 ENOG4108JU8 Transcriptional regulator ELJP9_RS11740 ENOG4106K28 UPF0283 membrane protein ELJP9_RS11745 ENOG4105CM6 amino acid regulated cytosolic protein ELJP9_RS11750 ENOG4105FKQ transcriptional regulator ELJP9_RS11755 ENOG4107EFV Outer membrane protein G ELJP9_RS11760 ENOG4108IJ9 (ABC) transporter ELJP9_RS11765 ENOG4107URF beta-phospho-glucomutase ELJP9_RS11770 ENOG4105C71 hydrolase family 65, central catalytic ELJP9_RS11775 ENOG4105CK5 oxidoreductase ELJP9_RS11780 ENOG4107TYA transient receptor potential locus ELJP9_RS11785 ENOG4107RRD Dehydrogenase ELJP9_RS11790 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component ELJP9_RS11795 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component ELJP9_RS11800 ENOG4105WEM extracellular solute-binding protein ELJP9_RS11805 ENOG4107QW3 Sucrose phosphorylase ELJP9_RS11810 ENOG4105NNG Peripheral inner membrane phage-shock protein ELJP9_RS11815 ENOG4105FM1 phage shock protein C ELJP9_RS11820 ENOG4105YYT phage shock protein B ELJP9_RS11825 ENOG41087YS Phage shock protein A ELJP9_RS11830 ENOG4105E51 psp operon transcriptional activator ELJP9_RS11835 ENOG4108J59 Extracellular solute-binding protein, family 5 ELJP9_RS11840 ENOG4108EKA peptide transport system, permease ELJP9_RS11845 ENOG4108EU3 peptide transport system, permease ELJP9_RS11850 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein ELJP9_RS11855 ENOG4108JQ2 peptide transport system atp-binding protein ELJP9_RS11865 ENOG4108UQ8 endoribonuclease L-psp ELJP9_RS11875 ENOG4105BZU Histidine kinase ELJP9_RS11880 ENOG4108TUY outer membrane protein PgaA ELJP9_RS11885 ENOG4108ZX5 transcriptional regulator ELJP9_RS11890 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH ELJP9_RS11895 ENOG4105Q4T oxidoreductase ELJP9_RS11900 ENOG4108IEC Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) ELJP9_RS11905 ENOG4105BZU Histidine kinase ELJP9_RS11910 ENOG4105E39 Enoyl-CoA hydratase ELJP9_RS11915 ENOG410643D UPF0509 protein ELJP9_RS11920 ENOG4105N2W Transcriptional regulator ELJP9_RS11925 ENOG41061RM osmotically inducible lipoprotein ELJP9_RS11930 ENOG4108ZJT translation initiation factor, Sui1 ELJP9_RS11935 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) ELJP9_RS11940 ENOG4105CFV Tetratricopeptide repeat protein ELJP9_RS11945 ENOG4105Q4A inner membrane protein yciS ELJP9_RS11950 ENOG4105EYK Phosphatidylglycerophosphatase B ELJP9_RS11960 ENOG4107QM5 aconitate hydratase ELJP9_RS11975 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ELJP9_RS11980 ENOG4105RKX Protein of unknown function (DUF2498) ELJP9_RS11985 ENOG4105ERU peptidase ELJP9_RS11990 ENOG4105UBK short-chain dehydrogenase reductase ELJP9_RS11995 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase ELJP9_RS12000 ENOG4105FE9 pseudouridine synthase ELJP9_RS12005 ENOG4107RTD sua5 ycio yrdc ywlc family protein ELJP9_RS12010 ENOG4105DB7 PHP domain protein ELJP9_RS12020 ENOG4105CRQ synthase (Component I) ELJP9_RS12025 ENOG4108EFP Anthranilate synthase component II ELJP9_RS12030 ENOG4105DK0 Indole-3-glycerol phosphate synthase ELJP9_RS12040 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) ELJP9_RS12050 ENOG4105CHR reductase ELJP9_RS12095 ENOG4105EQ2 LysR family Transcriptional regulator ELJP9_RS12105 ENOG4105CV8 reductase ELJP9_RS12110 ENOG4105CUY Mechanosensitive ion channel ELJP9_RS12130 ENOG4108T65 Fimbrial ELJP9_RS12140 ENOG4105CW0 outer membrane usher protein ELJP9_RS12145 ENOG4108VCD Chaperone ELJP9_RS12180 ENOG4105K56 Transcriptional regulator ELJP9_RS12200 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) ELJP9_RS12210 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr ELJP9_RS12225 ENOG4105BZU Histidine kinase ELJP9_RS12230 ENOG4105E3W Two component transcriptional regulator (Winged helix family ELJP9_RS12240 ENOG4105DND Transcriptional regulator ELJP9_RS12250 ENOG4105E7U AraC family transcriptional regulator ELJP9_RS12255 ENOG4105EMU Dehydrogenase ELJP9_RS12260 ENOG4105EMU Dehydrogenase ELJP9_RS12265 ENOG4105EQ2 LysR family Transcriptional regulator ELJP9_RS12270 ENOG4105HEI LysR family (Transcriptional regulator ELJP9_RS12280 ENOG4105CB2 alcohol dehydrogenase ELJP9_RS12305 ENOG41066VF YeeE YedE family protein ELJP9_RS12315 ENOG4108RW8 Universal stress protein F ELJP9_RS12330 ENOG4105EIF outer membrane protein W ELJP9_RS12335 ENOG4105PI0 Ferredoxin ELJP9_RS12340 ENOG4108S3I UPF0259 membrane protein ELJP9_RS12345 ENOG4107835 probably involved in intracellular septation (By similarity) ELJP9_RS12350 ENOG4105NAU thioesterase Superfamily protein ELJP9_RS12355 ENOG410822N TonB family ELJP9_RS12360 ENOG4105K9H YciI-like protein ELJP9_RS12365 ENOG4108NIW Leucine export protein LeuE ELJP9_RS12380 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ELJP9_RS12385 ENOG4108W5H UPF0263 protein ELJP9_RS12390 ENOG4105EYW Ion transport protein ELJP9_RS12395 ENOG4108JQ7 (ABC) transporter ELJP9_RS12400 ENOG4105C3U ABC transporter ELJP9_RS12405 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ELJP9_RS12410 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ELJP9_RS12415 ENOG4107QSI ABC, transporter ELJP9_RS12420 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein ELJP9_RS12430 ENOG4107104 thymidine kinase ELJP9_RS12440 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ELJP9_RS12445 ENOG4105I93 response regulator ELJP9_RS12450 ENOG4105D78 K07001 NTE family protein ELJP9_RS12455 ENOG4105K5B UPF0225 protein ELJP9_RS12460 ENOG4105CIY formyltetrahydrofolate deformylase ELJP9_RS12530 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase ELJP9_RS12535 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) ELJP9_RS12540 ENOG41076YT nitrate reductase, gamma subunit ELJP9_RS12545 ENOG4105R3A Nitrate reductase ELJP9_RS12550 ENOG4108IUE nitrate reductase beta subunit ELJP9_RS12555 ENOG4105CRU nitrate reductase, alpha subunit ELJP9_RS12560 ENOG4105DQQ Major facilitator superfamily MFS_1 ELJP9_RS12565 ENOG4105BZU Histidine kinase ELJP9_RS12570 ENOG4105WH1 Two component transcriptional regulator luxr family ELJP9_RS12575 ENOG4105ID0 Putative invasin ELJP9_RS12585 ENOG4107QZF nitrite reductase NADPH large subunit ELJP9_RS12590 ENOG4105D7T ABC transporter ELJP9_RS12615 ENOG41090EX DsrE family ELJP9_RS12620 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS12630 ENOG4108NH8 Cation transport protein ELJP9_RS12635 ENOG4105WS7 Cation transport regulator ELJP9_RS12640 ENOG4105EWV Sodium calcium exchanger membrane region ELJP9_RS12645 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ELJP9_RS12650 ENOG41063JG Transcriptional regulator ELJP9_RS12655 ENOG4108YY7 Invasion gene expression up-regulator SirB ELJP9_RS12660 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ELJP9_RS12670 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) ELJP9_RS12675 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) ELJP9_RS12680 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) ELJP9_RS12685 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ELJP9_RS12690 ENOG4105CHH sulfate transporter ELJP9_RS12700 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria ELJP9_RS12705 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) ELJP9_RS12710 ENOG4105C3G gtp-binding protein ELJP9_RS12730 ENOG4105CS6 Rhs element vgr protein ELJP9_RS12760 ENOG4105D9P serine threonine protein kinase ELJP9_RS12765 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ELJP9_RS12815 ENOG4108WC9 type VI secretion system effector, hcp1 family ELJP9_RS12855 ENOG4106VK6 Flagellar motor protein ELJP9_RS12875 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit ELJP9_RS12880 ENOG4105C5Q Transcriptional regulator ELJP9_RS12905 ENOG4107RTG Major Facilitator superfamily ELJP9_RS12920 ENOG4105E0K tonB-dependent siderophore receptor ELJP9_RS12930 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) ELJP9_RS12935 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division ELJP9_RS12940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A ELJP9_RS12945 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) ELJP9_RS12950 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ELJP9_RS12955 ENOG4105MWK D-amino acid dehydrogenase, small subunit ELJP9_RS12960 ENOG4105ED1 spovr family ELJP9_RS12965 ENOG4105C05 Multifunctional regulator of fatty acid metabolism (By similarity) ELJP9_RS12970 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) ELJP9_RS12975 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) ELJP9_RS12980 ENOG4108ZZ3 UPF0260 protein ELJP9_RS12985 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase ELJP9_RS12995 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) ELJP9_RS13000 ENOG4107QMS site-determining protein ELJP9_RS13005 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) ELJP9_RS13010 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) ELJP9_RS13015 ENOG4105CEY Amp-dependent synthetase and ligase ELJP9_RS13020 ENOG4105Y4Z Outer Membrane Lipoprotein ELJP9_RS13025 ENOG41072GX Peptidase M22 Glycoprotease ELJP9_RS13030 ENOG4105DVT helicase ELJP9_RS13035 ENOG4105M4H endoribonuclease L-psp ELJP9_RS13040 ENOG4105X5C UPF0181 protein ELJP9_RS13045 ENOG4105CRQ synthase (Component I) ELJP9_RS13050 ENOG4105P8F nudix hydrolase ELJP9_RS13055 ENOG4105EJQ L-serine dehydratase ELJP9_RS13060 ENOG4107XTP (EAL) domain protein ELJP9_RS13065 ENOG4105EE5 Membrane protein terC ELJP9_RS13070 ENOG4105DAS pts system ELJP9_RS13075 ENOG4105ETZ PTS System ELJP9_RS13080 ENOG4105F3R pts system mannose fructose sorbose family iid ELJP9_RS13085 ENOG4108NK4 UPF0266 membrane protein ELJP9_RS13090 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) ELJP9_RS13095 ENOG4105DHI Methyltransferase ELJP9_RS13100 ENOG4105CJN penicillin-binding protein ELJP9_RS13120 ENOG4105Q3Y exported protein ELJP9_RS13125 ENOG4106CCY Protein MgrB homolog ELJP9_RS13130 ENOG4105TIK ELJP9_RS13135 ENOG4105J4Q Transcriptional regulator ELJP9_RS13140 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS13145 ENOG4105D0M Protease HtpX homolog ELJP9_RS13150 ENOG4105CN1 protease ELJP9_RS13160 ENOG4108ZGC gaf domain protein ELJP9_RS13165 ENOG4105H2K paraquat-inducible protein a ELJP9_RS13175 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ELJP9_RS13180 ENOG4105WT8 Protein of unknown function (DUF1480) ELJP9_RS13185 ENOG4108R1E Serine threonine protein phosphatase 1 ELJP9_RS13190 ENOG4108MJ5 VirK protein ELJP9_RS13195 ENOG4105NKT exported protein ELJP9_RS13200 ENOG4108PNC copper resistance ELJP9_RS13205 ENOG4105FXM Copper resistance protein ELJP9_RS13210 ENOG4105MPK DNA polymerase III subunit theta ELJP9_RS13215 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ELJP9_RS13220 ENOG4105UMD exodeoxyribonuclease X ELJP9_RS13225 ENOG4105CUG Oligopeptidase b ELJP9_RS13230 ENOG4108Q2J Inner membrane protein YebE ELJP9_RS13240 ENOG4108UHU Aldolase ELJP9_RS13245 ENOG4105C01 Dihydroxy-acid dehydratase ELJP9_RS13250 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ELJP9_RS13255 ENOG4106KNT transcriptional regulator ELJP9_RS13260 ENOG4105CA9 Pyruvate kinase ELJP9_RS13265 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase ELJP9_RS13270 ENOG4105DR5 peptidase ELJP9_RS13275 ENOG4105NXV High-affinity zinc uptake system protein ELJP9_RS13285 ENOG4105FAV ABC, transporter ELJP9_RS13290 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) ELJP9_RS13295 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) ELJP9_RS13300 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) ELJP9_RS13305 ENOG4105CDY transcriptional regulatory protein ELJP9_RS13310 ENOG4108TIT dATP pyrophosphohydrolase ELJP9_RS13315 ENOG4105C9M aspartyl-trna synthetase ELJP9_RS13320 ENOG4105D3W isochorismatase ELJP9_RS13325 ENOG41081XQ Conserved Protein ELJP9_RS13330 ENOG4105WJG Glutathione ELJP9_RS13340 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) ELJP9_RS13345 ENOG4106N3A copper homeostasis protein cutc ELJP9_RS13350 ENOG4106ZCM YecM protein ELJP9_RS13355 ENOG4105C75 arginyL-tRNA synthetase ELJP9_RS13360 ENOG4105F5H Glycosyl Hydrolase Family 88 ELJP9_RS13365 ENOG4105CT4 transporter ELJP9_RS13370 ENOG4105W13 flagellar protein ELJP9_RS13375 ENOG4105D7B Flagellar biosynthesis protein flha ELJP9_RS13380 ENOG4105D00 flagellar biosynthetic protein flhB ELJP9_RS13390 ENOG4108VYJ response regulator receiver protein ELJP9_RS13395 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) ELJP9_RS13400 ENOG4105BZU Histidine kinase ELJP9_RS13405 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS13410 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS13440 ENOG4107QJT sodium dicarboxylate symporter ELJP9_RS13445 ENOG4108V3W Chemotaxis protein, CheW ELJP9_RS13450 ENOG4105CBS Chea signal transduction histidine kinase ELJP9_RS13455 ENOG4105ER2 Ompa motb domain protein ELJP9_RS13460 ENOG4107RD7 Flagellar Motor Protein, MotA ELJP9_RS13465 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region ELJP9_RS13470 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) ELJP9_RS13475 ENOG4108VA4 Universal stress protein ELJP9_RS13480 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase ELJP9_RS13485 ENOG4108K4C ec 3.1.3.12 ELJP9_RS13490 ENOG4105CNN ABC, transporter ELJP9_RS13500 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator ELJP9_RS13510 ENOG4108UEC Ferritin-like protein ELJP9_RS13515 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter ELJP9_RS13520 ENOG4105N4N Protein of unknown function (DUF2766) ELJP9_RS13535 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase ELJP9_RS13545 ENOG41090A1 ferritin ELJP9_RS13555 ENOG4105E0U tyrosine-specific transport protein ELJP9_RS13560 ENOG4106RHG Yeca family ELJP9_RS13570 ENOG4105C32 Amino acid ABC transporter (Permease) ELJP9_RS13575 ENOG4105CF8 branched-chain amino acid ABC transporter, permease ELJP9_RS13580 ENOG4105C0Z ABC transporter ELJP9_RS13585 ENOG4108IV0 ABC, transporter ELJP9_RS13590 ENOG41060EU Cold shock-like protein ELJP9_RS13595 ENOG4105VEQ Cold shock protein ELJP9_RS13605 ENOG4106IAW ELJP9_RS13610 ENOG4107EDW L-fucose operon activator ELJP9_RS13615 ENOG4105NWF RbsD or FucU transport ELJP9_RS13620 ENOG4105CMG Carbohydrate kinase ELJP9_RS13625 ENOG4105EHF Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity) ELJP9_RS13630 ENOG4105EDR glucose galactose transporter ELJP9_RS13635 ENOG4107W7X Aldolase ELJP9_RS13640 ENOG4105C0A alcohol dehydrogenase ELJP9_RS13665 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) ELJP9_RS13670 ENOG4105WH1 Two component transcriptional regulator luxr family ELJP9_RS13675 ENOG4105XVG cytoplasmic protein ELJP9_RS13680 ENOG4105VJY transcriptional regulator ELJP9_RS13685 ENOG4105CDA abc transporter atp-binding protein ELJP9_RS13690 ENOG4105E5Q amino acid AbC transporter ELJP9_RS13700 ENOG4105EAB amino acid AbC transporter ELJP9_RS13705 ENOG4108M9K flagella biosynthesis protein FliZ ELJP9_RS13710 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ELJP9_RS13735 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) ELJP9_RS13750 ENOG4105DTS flagellar hook-associated ELJP9_RS13755 ENOG4105MQ3 flagellar protein FliS ELJP9_RS13760 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) ELJP9_RS13765 ENOG4105E5K Alpha-amylase ELJP9_RS13770 ENOG4108W9D (LipO)protein ELJP9_RS13780 ENOG4105VQ0 flagellar hook-basal body complex protein fliE ELJP9_RS13785 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) ELJP9_RS13790 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ELJP9_RS13795 ENOG41090PJ Flagellar assembly protein ELJP9_RS13800 ENOG4108JIR Flagellum-specific ATP synthase ELJP9_RS13805 ENOG4105GSA Flagellar export protein flij ELJP9_RS13810 ENOG4105WF4 Flagellar hook-length control protein ELJP9_RS13815 ENOG4107ZI8 flagellar basal body-associated protein flil ELJP9_RS13820 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ELJP9_RS13825 ENOG4105DD5 Flagellar motor switch protein ELJP9_RS13830 ENOG4105K0P flagellar biosynthesis protein ELJP9_RS13835 ENOG4105CN7 Flagellar biosynthetic protein FliP ELJP9_RS13845 ENOG4105D19 Role in flagellar biosynthesis (By similarity) ELJP9_RS13850 ENOG4107TKS colanic acid capsular biosynthesis activation protein A ELJP9_RS13860 ENOG4105YX3 cellular response to acidity ELJP9_RS13865 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase ELJP9_RS13875 ENOG4105VNZ cytoplasmic protein ELJP9_RS13880 ENOG4105CKW Inner membrane protein yedI ELJP9_RS13885 ENOG4105FDR Membrane ELJP9_RS13890 ENOG41090BB DNA mismatch endonuclease (vsr) ELJP9_RS13895 ENOG4105DVF Cytosine-specific methyltransferase ELJP9_RS13900 ENOG4105EST Metal Dependent Phosphohydrolase ELJP9_RS13905 ENOG4105FCK Membrane ELJP9_RS13910 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate ELJP9_RS13920 ENOG4108MRH transcriptional regulatory protein ELJP9_RS13940 ENOG4107GFK fumarate ELJP9_RS13955 ENOG4105CSH Transporter ELJP9_RS13965 ENOG4105F04 LysR family Transcriptional regulator ELJP9_RS13990 ENOG4105DUU IucA IucC family protein ELJP9_RS13995 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) ELJP9_RS14010 ENOG4105ETT transcriptional Regulator, LysR family ELJP9_RS14020 ENOG4107R11 Transcriptional regulator ELJP9_RS14035 ENOG4108PXI ErfK YbiS YcfS YnhG ELJP9_RS14040 ENOG4105CSH Transporter ELJP9_RS14045 ENOG4105FYV Amp nucleosidase ELJP9_RS14050 ENOG4105DC7 peptidase M24 ELJP9_RS14060 ENOG4105UQX Mate efflux family protein ELJP9_RS14080 ENOG4105DR8 Membrane ELJP9_RS14085 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) ELJP9_RS14090 ENOG4105DZ1 carboxypeptidase ELJP9_RS14095 ENOG4105CJB Exodeoxyribonuclease I ELJP9_RS14100 ENOG4105CUB amino acid ELJP9_RS14110 ENOG4105EQ1 Transcriptional regulator ELJP9_RS14115 ENOG4107SRH Nad-dependent epimerase dehydratase ELJP9_RS14125 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) ELJP9_RS14135 ENOG4105CIH Imidazole acetol-phosphate transaminase ELJP9_RS14140 ENOG4105ECC imidazole-glycerol-phosphate dehydratase ELJP9_RS14145 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ELJP9_RS14150 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase ELJP9_RS14155 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) ELJP9_RS14165 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) ELJP9_RS14180 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) ELJP9_RS14195 ENOG4107T8Q Glycosyl transferase (Group 1 ELJP9_RS14200 ENOG4105H63 Glycosyl transferase, family 2 ELJP9_RS14210 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase ELJP9_RS14215 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) ELJP9_RS14220 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase ELJP9_RS14225 ENOG4105C1B dTDP-glucose 4-6-dehydratase ELJP9_RS14230 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ELJP9_RS14235 ENOG4105G1A colanic acid biosynthesis protein ELJP9_RS14240 ENOG4107T8Q Glycosyl transferase (Group 1 ELJP9_RS14245 ENOG4105C74 pyruvyl transferase ELJP9_RS14250 ENOG4105PSV Polysaccharide Biosynthesis Protein ELJP9_RS14255 ENOG4105D3Q Sugar transferase ELJP9_RS14260 ENOG4107QKV phosphomannomutase ELJP9_RS14265 ENOG4105CJT Mannose-1-phosphate guanylyltransferase ELJP9_RS14270 ENOG4106CD9 glycosyl transferase group 1 ELJP9_RS14275 ENOG4105FGF GDP-mannose mannosyl hydrolase ELJP9_RS14280 ENOG4105C30 Nad-dependent epimerase dehydratase ELJP9_RS14285 ENOG4105C0K Gdp-mannose 4,6-dehydratase ELJP9_RS14290 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF ELJP9_RS14295 ENOG4105ECJ Glycosyl Transferase ELJP9_RS14305 ENOG4107RXY Glycosyl transferase ELJP9_RS14310 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB ELJP9_RS14315 ENOG41090RK glycosyl transferase ELJP9_RS14320 ENOG4105D75 Capsular exopolysaccharide family ELJP9_RS14325 ENOG4105KJF protein tyrosine phosphatase ELJP9_RS14330 ENOG4105DAY polysaccharide export protein ELJP9_RS14335 ENOG4105EE5 Membrane protein terC ELJP9_RS14340 ENOG4108GAE asmA family ELJP9_RS14345 ENOG4105DHP deoxycytidine triphosphate deaminase ELJP9_RS14355 ENOG4105BZU Histidine kinase ELJP9_RS14360 ENOG4105D03 DNA-3-methyladenine glycosylase II ELJP9_RS14365 ENOG4105R8A Heat shock protein ELJP9_RS14370 ENOG4105BZU Histidine kinase ELJP9_RS14390 ENOG4106PYX Receptor ELJP9_RS14410 ENOG4105ENT Efflux transporter rnd family, mfp subunit ELJP9_RS14415 ENOG4105BZS acriflavin resistance protein ELJP9_RS14420 ENOG4105BZS acriflavin resistance protein ELJP9_RS14425 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS14430 ENOG4105EB3 Histidine kinase ELJP9_RS14435 ENOG4105E3W Two component transcriptional regulator (Winged helix family ELJP9_RS14440 ENOG4105KWI UPF0339 protein ELJP9_RS14445 ENOG4105CFP Peptidase U32 ELJP9_RS14450 ENOG4107TE5 Lipid kinase ELJP9_RS14455 ENOG4105EIE fructose-bisphosphate aldolase ELJP9_RS14460 ENOG4105EAA nucleoside ELJP9_RS14465 ENOG4108KD5 ADP-ribosylation crystallin J1 ELJP9_RS14470 ENOG4108TFM Kinase, PfkB family ELJP9_RS14475 ENOG4105FDP GntR family transcriptional regulator ELJP9_RS14480 ENOG4105DWF phosphomethylpyrimidine kinase ELJP9_RS14485 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase ELJP9_RS14495 ENOG4105DY8 decarboxylase ELJP9_RS14500 ENOG4105N2G alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ELJP9_RS14505 ENOG4105DUM transcriptional regulator, lysR family ELJP9_RS14510 ENOG4105CPN adenine deaminase ELJP9_RS14515 ENOG4105C7N Xanthine uracil vitamin C permease ELJP9_RS14525 ENOG4107ZF2 Phosphatase ELJP9_RS14530 ENOG4105DAY polysaccharide export protein ELJP9_RS14535 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly ELJP9_RS14540 ENOG4105M4B Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity) ELJP9_RS14545 ENOG4105D1F ATP-binding protein ELJP9_RS14555 ENOG4108W15 Protein of unknown function (DUF1456) ELJP9_RS14560 ENOG4108NEV two component transcriptional regulator, LytTR family ELJP9_RS14565 ENOG4108HRK Histidine kinase ELJP9_RS14570 ENOG4108XDN Transcriptional regulator ELJP9_RS14580 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component ELJP9_RS14585 ENOG4108IJ8 ABC transporter ELJP9_RS14590 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component ELJP9_RS14595 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system ELJP9_RS14600 ENOG4107QK4 glycoside hydrolase, family 3 domain protein ELJP9_RS14605 ENOG4105CXG d-lactate dehydrogenase ELJP9_RS14615 ENOG41061WM D-Alanyl-D-Alanine ELJP9_RS14620 ENOG41069YE inner membrane protein yohC ELJP9_RS14625 ENOG4105KHU inner membrane protein YohD ELJP9_RS14630 ENOG4105H9W Short-chain dehydrogenase reductase Sdr ELJP9_RS14645 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) ELJP9_RS14650 ENOG4105VAW lrga family ELJP9_RS14655 ENOG41067MG lrgb family ELJP9_RS14660 ENOG4107T42 This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity) ELJP9_RS14665 ENOG4107GZ4 SanA protein ELJP9_RS14670 ENOG4105CFQ glutamine synthetase ELJP9_RS14675 ENOG4107SDZ Galactoside transport system permease protein mglC ELJP9_RS14680 ENOG4105C2J ABC transporter ELJP9_RS14690 ENOG41060NJ transcriptional regulator ELJP9_RS14695 ENOG4105DHF Membrane ELJP9_RS14700 ENOG4105EUJ GTP cyclohydrolase i ELJP9_RS14705 ENOG4105CBP Major Facilitator ELJP9_RS14715 ENOG4105D05 Receptor ELJP9_RS14720 ENOG4108IQI permease ELJP9_RS14725 ENOG4105DUM transcriptional regulator, lysR family ELJP9_RS14730 ENOG4105HMI Membrane ELJP9_RS14735 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) ELJP9_RS14740 ENOG4105DM4 PTS System ELJP9_RS14745 ENOG4105DE4 1-phosphofructokinase ELJP9_RS14750 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein ELJP9_RS14755 ENOG4105S8Q sugar efflux transporter ELJP9_RS14760 ENOG4105KRS Proteinase inhibitor ELJP9_RS14765 ENOG4105FUQ Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) ELJP9_RS14770 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) ELJP9_RS14775 ENOG4105DEI Mannitol dehydrogenase ELJP9_RS14780 ENOG4105CKI cobalamin synthesis protein ELJP9_RS14785 ENOG41076MN Phosphoesterase, PA-phosphatase related ELJP9_RS14790 ENOG4107TT5 NLP P60 protein ELJP9_RS14795 ENOG4105CXC rtn protein ELJP9_RS14800 ENOG4105E43 Extracellular solute-binding protein, family 5 ELJP9_RS14805 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component ELJP9_RS14810 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component ELJP9_RS14815 ENOG4108JQ5 ABC transporter ELJP9_RS14820 ENOG4105HG6 ELJP9_RS14825 ENOG4105C2C drug resistance transporter, Bcr CflA ELJP9_RS14830 ENOG4105I08 Pseudouridine synthase ELJP9_RS14835 ENOG4105CFI type iii restriction protein res subunit ELJP9_RS14840 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) ELJP9_RS14845 ENOG4106V8H Nucleoid-associated protein ELJP9_RS14850 ENOG4105PAN UPF0352 protein ELJP9_RS14855 ENOG4105E68 Sulfatase ELJP9_RS14865 ENOG4105Y50 Virulence Protein ELJP9_RS14890 ENOG4105S5I Membrane ELJP9_RS14900 ENOG4105DWT malate dehydrogenase (quinone) ELJP9_RS14910 ENOG4105CJW magnesium transporter ELJP9_RS14915 ENOG4105IBP Cyclic peptide transporter ELJP9_RS14920 ENOG4105CF1 Alkylated DNA repair protein ELJP9_RS14925 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ELJP9_RS14935 ENOG4105FCK Membrane ELJP9_RS14940 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC ELJP9_RS14945 ENOG41068CG regulatoR ELJP9_RS14950 ENOG4105BZU Histidine kinase ELJP9_RS14955 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ELJP9_RS14960 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) ELJP9_RS14965 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ELJP9_RS14970 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ELJP9_RS14975 ENOG4105XPH Ferredoxin ELJP9_RS14980 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase ELJP9_RS14985 ENOG4105CXY transporter ELJP9_RS14990 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A ELJP9_RS14995 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B ELJP9_RS15000 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ELJP9_RS15005 ENOG4108EWA cinA-like protein ELJP9_RS15010 ENOG4108UII YfaZ family ELJP9_RS15015 ENOG4106F60 Histidine kinase ELJP9_RS15040 ENOG4105CEY Amp-dependent synthetase and ligase ELJP9_RS15045 ENOG4105DNI Converts SHCHC to OSB (By similarity) ELJP9_RS15050 ENOG4108IPT Naphthoate synthase ELJP9_RS15055 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) ELJP9_RS15060 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) ELJP9_RS15065 ENOG4105E4F Isochorismate synthase ELJP9_RS15070 ENOG4105TNS Conserved Protein ELJP9_RS15075 ENOG4107YB6 acetyltransferase, (GNAT) family ELJP9_RS15080 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) ELJP9_RS15090 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ELJP9_RS15095 ENOG4105C8S subunit m ELJP9_RS15100 ENOG4105D65 subunit l ELJP9_RS15105 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ELJP9_RS15110 ENOG4107UFS subunit j ELJP9_RS15120 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) ELJP9_RS15125 ENOG4108IEH NADH dehydrogenase subunit g ELJP9_RS15130 ENOG4107QIZ NADH dehydrogenase ELJP9_RS15135 ENOG4105GKE subunit e ELJP9_RS15140 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ELJP9_RS15145 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ELJP9_RS15150 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain ELJP9_RS15155 ENOG4107NQ8 LysR family Transcriptional regulator ELJP9_RS15160 ENOG4105CHM Aminotransferase ELJP9_RS15165 ENOG4105DK2 UPF0207 protein ELJP9_RS15170 ENOG4107QWE )-transporter ELJP9_RS15175 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 ELJP9_RS15180 ENOG4105XWI UPF0304 protein ELJP9_RS15190 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ELJP9_RS15195 ENOG4105C6K Malic enzyme ELJP9_RS15200 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) ELJP9_RS15205 ENOG4108HHA Transketolase ELJP9_RS15210 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC ELJP9_RS15220 ENOG4106ETB IIa component ELJP9_RS15225 ENOG4105K2J Transcriptional regulator ELJP9_RS15230 ENOG4105PTV Nudix Hydrolase ELJP9_RS15235 ENOG4108RE9 Phosphodiesterase ELJP9_RS15240 ENOG4108SHQ Glutathione S-transferase ELJP9_RS15245 ENOG4105CYM Glutathione S-transferase ELJP9_RS15250 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase ELJP9_RS15255 ENOG4105ECP epimerase ELJP9_RS15265 ENOG4108JEH abc transporter atp-binding protein ELJP9_RS15270 ENOG4106YG3 ABC transporter ELJP9_RS15275 ENOG4105DSP amino acid AbC transporter ELJP9_RS15280 ENOG4105E89 ABC transporter ELJP9_RS15285 ENOG4105E89 ABC transporter ELJP9_RS15290 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ELJP9_RS15295 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase ELJP9_RS15300 ENOG4105E96 Colicin v production protein ELJP9_RS15310 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ELJP9_RS15315 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) ELJP9_RS15320 ENOG4105DQR SNARE associated Golgi ELJP9_RS15325 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) ELJP9_RS15330 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ELJP9_RS15335 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) ELJP9_RS15340 ENOG4106WZ1 flagella biosynthesis regulator ELJP9_RS15345 ENOG4105F9N Major Facilitator Superfamily ELJP9_RS15350 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ELJP9_RS15355 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) ELJP9_RS15360 ENOG4105MH2 YfcL protein ELJP9_RS15365 ENOG4108BPE -transporting atpase ELJP9_RS15370 ENOG4105EJ9 Membrane ELJP9_RS15380 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase ELJP9_RS15385 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) ELJP9_RS15390 ENOG4108DG9 Smr protein MutS2 ELJP9_RS15395 ENOG4108BY2 phosphohistidine phosphatase ELJP9_RS15400 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ELJP9_RS15405 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS15410 ENOG4105KZW UPF0381 protein ELJP9_RS15415 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation ELJP9_RS15420 ENOG410903C (LipO)protein ELJP9_RS15425 ENOG4105S64 Formate nitrite transporter ELJP9_RS15445 ENOG4105D1S lipid A biosynthesis ELJP9_RS15455 ENOG4105CHM Aminotransferase ELJP9_RS15460 ENOG4108HRK Histidine kinase ELJP9_RS15465 ENOG4105DY9 regulatoR ELJP9_RS15470 ENOG4105CHC glucokinase (EC 2.7.1.2) ELJP9_RS15480 ENOG4107RA9 decarboxylase ELJP9_RS15485 ENOG4105CPC Aldo Keto reductase ELJP9_RS15490 ENOG4109076 Conserved Protein ELJP9_RS15495 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) ELJP9_RS15500 ENOG4105D9N nucleoside ELJP9_RS15505 ENOG4108KMM Diguanylate cyclase ELJP9_RS15520 ENOG4105HZG regulatoR ELJP9_RS15525 ENOG4105GXM Putative transcription regulator (DUF1323) ELJP9_RS15530 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) ELJP9_RS15560 ENOG4105CN8 Transcriptional regulator ELJP9_RS15565 ENOG4105EAA nucleoside ELJP9_RS15570 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) ELJP9_RS15580 ENOG4108M0I Transcriptional regulator ELJP9_RS15585 ENOG4105DHU Bile acid ELJP9_RS15590 ENOG4105VRT cytoplasmic protein ELJP9_RS15595 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) ELJP9_RS15600 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) ELJP9_RS15605 ENOG4105EXN Sulfate transport protein CysZ ELJP9_RS15610 ENOG4105C6T cysteine synthase ELJP9_RS15625 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ELJP9_RS15630 ENOG4105C5Y PTS System ELJP9_RS15640 ENOG4105C6T cysteine synthase ELJP9_RS15645 ENOG4108IJ6 ABC transporter ELJP9_RS15650 ENOG4105ECW sulfate abc transporter ELJP9_RS15655 ENOG4108I5D sulfate abc transporter ELJP9_RS15660 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein ELJP9_RS15665 ENOG4105EZR dyp-type peroxidase family protein ELJP9_RS15670 ENOG4105E7K (LipO)protein ELJP9_RS15675 ENOG4105QZU Inner membrane protein YfeZ ELJP9_RS15680 ENOG4108R6G acetyltransferase ELJP9_RS15685 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase ELJP9_RS15690 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) ELJP9_RS15705 ENOG4105CV1 Transketolase (EC 2.2.1.1) ELJP9_RS15715 ENOG4107VIJ nudix hydrolase ELJP9_RS15720 ENOG4105BZ8 glutamate synthase ELJP9_RS15725 ENOG4105BZU Histidine kinase ELJP9_RS15730 ENOG4105BZS acriflavin resistance protein ELJP9_RS15740 ENOG4105KUZ arsenate reductase ELJP9_RS15745 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) ELJP9_RS15755 ENOG4106KED esterase YpfH ELJP9_RS15760 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) ELJP9_RS15765 ENOG4105CGZ zinc metallopeptidase ELJP9_RS15770 ENOG4105C8V SAICAR synthetase ELJP9_RS15775 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ELJP9_RS15785 ENOG4105RH4 Glycine cleavage system transcriptional repressor ELJP9_RS15790 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ELJP9_RS15795 ENOG4105C02 permease ELJP9_RS15800 ENOG4105ERG peptidase m48, ste24p ELJP9_RS15805 ENOG4105K89 arsenate reductase ELJP9_RS15825 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) ELJP9_RS15830 ENOG4108KZ1 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity) ELJP9_RS15835 ENOG4105C2W permease ELJP9_RS15840 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) ELJP9_RS15845 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS15855 ENOG4108V3E phosphoribosylglycinamide formyltransferase ELJP9_RS15865 ENOG4105C9X ppx gppa phosphatase ELJP9_RS15870 ENOG4105BZU Histidine kinase ELJP9_RS15875 ENOG41062G3 Protein of unknown function (DUF2633) ELJP9_RS15910 ENOG4105DH8 myo-inositol catabolism ELJP9_RS15920 ENOG4105EDK PfkB domain protein ELJP9_RS15930 ENOG4105CNN ABC, transporter ELJP9_RS15940 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ELJP9_RS15950 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) ELJP9_RS15955 ENOG4105C26 Dehydrogenase ELJP9_RS15970 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ELJP9_RS15975 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) ELJP9_RS15980 ENOG4105D4Y metalloprotease ELJP9_RS16000 ENOG4105DUX Transporter ELJP9_RS16005 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) ELJP9_RS16010 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ELJP9_RS16015 ENOG4105N21 Membrane ELJP9_RS16020 ENOG4105CUT histidyl-tRNA synthetase ELJP9_RS16025 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) ELJP9_RS16035 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs ELJP9_RS16040 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) ELJP9_RS16050 ENOG4105DN3 alpha-2-macroglobulin domain protein ELJP9_RS16055 ENOG4105CI1 PTS System ELJP9_RS16065 ENOG4105KHC sulfurtransferase ELJP9_RS16070 ENOG4108Q3X Transcriptional regulator ELJP9_RS16075 ENOG4105YYA enhanced serine sensitivity protein SseB ELJP9_RS16080 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) ELJP9_RS16085 ENOG4105WVQ Fe-S assembly protein IscX ELJP9_RS16090 ENOG4108ZIT Ferredoxin, 2FE-2S ELJP9_RS16095 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB ELJP9_RS16105 ENOG4108Z4V iron-sulfur cluster assembly ELJP9_RS16110 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins ELJP9_RS16115 ENOG4105C3J Cysteine desulfurase ELJP9_RS16120 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family ELJP9_RS16125 ENOG4105CVS RNA methyltransferase TrmH family, group 1 ELJP9_RS16130 ENOG4105ECY inositol monophosphatase ELJP9_RS16135 ENOG4105D7X high-affinity nickel-transporter ELJP9_RS16145 ENOG4108MN2 Stationary phase inducible protein CsiE ELJP9_RS16150 ENOG4105D8G Major Facilitator superfamily ELJP9_RS16155 ENOG4108SB3 DoxX Family ELJP9_RS16160 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) ELJP9_RS16165 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ELJP9_RS16170 ENOG4108YZA Nitrogen regulatory protein pii ELJP9_RS16175 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ELJP9_RS16180 ENOG4108SKK alpha helix protein ELJP9_RS16185 ENOG4107WP9 Histidine kinase ELJP9_RS16190 ENOG4108ETH Formylglycinamide ribotide synthetase ELJP9_RS16195 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) ELJP9_RS16200 ENOG4108Z6B deaminase ELJP9_RS16205 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB ELJP9_RS16215 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate ELJP9_RS16220 ENOG4106G6Q Transcriptional regulator ELJP9_RS16225 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding ELJP9_RS16235 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) ELJP9_RS16240 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) ELJP9_RS16245 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) ELJP9_RS16250 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) ELJP9_RS16255 ENOG4105C3F Signal peptidase i ELJP9_RS16260 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) ELJP9_RS16265 ENOG4105WMJ Positive regulator of sigma E, RseC MucC ELJP9_RS16275 ENOG41069PW sigma-e factor negative regulatory protein ELJP9_RS16295 ENOG4108IYU L-aspartate oxidase ELJP9_RS16300 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) ELJP9_RS16305 ENOG4105C1J atp-dependent rna helicase ELJP9_RS16310 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) ELJP9_RS16320 ENOG4105EIB trna rrna methyltransferase ELJP9_RS16325 ENOG4105K63 Thioredoxin ELJP9_RS16330 ENOG4106IUH DTW domain containing protein ELJP9_RS16335 ENOG4105CD5 CoA-binding domain protein ELJP9_RS16340 ENOG4105JIM Phosphatidylserine synthase ELJP9_RS16345 ENOG4105T42 (LipO)protein ELJP9_RS16350 ENOG4105CSH Transporter ELJP9_RS16375 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ELJP9_RS16380 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ELJP9_RS16385 ENOG4105C34 Pseudouridine synthase ELJP9_RS16390 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane ELJP9_RS16395 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA ELJP9_RS16405 ENOG4105CQC Prephenate dehydratase ELJP9_RS16415 ENOG4105EHE chorismate mutase- prephenate dehydrogenase ELJP9_RS16420 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) ELJP9_RS16425 ENOG4105QP9 Protein of unknown function (DUF2799) ELJP9_RS16430 ENOG4108WS1 ELJP9_RS16435 ENOG4108KHX Diguanylate cyclase ELJP9_RS16440 ENOG41090EK ompa motb domain protein ELJP9_RS16455 ENOG4108RS6 transposase ELJP9_RS16460 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) ELJP9_RS16465 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) ELJP9_RS16470 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) ELJP9_RS16475 ENOG4105K5M 30s ribosomal protein S16 ELJP9_RS16480 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ELJP9_RS16485 ENOG4106KVJ cytochrome C assembly protein ELJP9_RS16490 ENOG4108JU6 CBS domain protein ELJP9_RS16495 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ ELJP9_RS16500 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ELJP9_RS16505 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ELJP9_RS16515 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) ELJP9_RS16520 ENOG4105VDB UPF0125 protein ELJP9_RS16525 ENOG4108Z1B Cyclase dehydrase ELJP9_RS16540 ENOG4105DFP Integrase ELJP9_RS16625 ENOG4105TS0 gtp-binding protein ELJP9_RS16630 ENOG4106H6R UPF0380 protein ELJP9_RS16635 ENOG4108KZE transcriptional regulator ELJP9_RS16655 ENOG4106ZN7 UPF0401 protein YkfF ELJP9_RS16660 ENOG4105MFG Antirestriction protein ELJP9_RS16665 ENOG4108XS9 dna repair protein ELJP9_RS16670 ENOG4105ZS6 Protein of unknown function (DUF987) ELJP9_RS16675 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles ELJP9_RS16750 ENOG4108RJ7 Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity) ELJP9_RS16755 ENOG4106ZGR Transcriptional regulator ELJP9_RS16770 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ELJP9_RS16785 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ELJP9_RS16805 ENOG4105DJB Major Facilitator Superfamily ELJP9_RS16815 ENOG4105DZC cytosine deaminase ELJP9_RS16820 ENOG4105C5B carbamate kinase ELJP9_RS16830 ENOG4107REC cytoplasmic protein ELJP9_RS16835 ENOG4107R1Q Membrane protein FdrA ELJP9_RS16840 ENOG4107SNB ankyrin repeat protein YahD ELJP9_RS16845 ENOG4108NUU Transcriptional regulator ELJP9_RS16850 ENOG4105VPI YqaE family transport protein ELJP9_RS16855 ENOG41080HT Transcriptional regulator, arsr family ELJP9_RS16860 ENOG4108V62 Rhodanese domain protein ELJP9_RS16870 ENOG4108X73 DNA- binding protein ELJP9_RS16875 ENOG4108RNS Exports L-alanine (By similarity) ELJP9_RS16880 ENOG4108WMJ Protein of unknown function (DUF2002) ELJP9_RS16885 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) ELJP9_RS16890 ENOG4105WAZ (Glutaredoxin-like protein) NrdH ELJP9_RS16895 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) ELJP9_RS16900 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ELJP9_RS16905 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ELJP9_RS16915 ENOG4108HQS Glycine betaine ELJP9_RS16920 ENOG4105GIJ Glycine betaine ELJP9_RS16930 ENOG4105NTK Transcriptional repressor Mpra ELJP9_RS16935 ENOG4105CW7 secretion protein, HlyD family ELJP9_RS16940 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS16945 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) ELJP9_RS16955 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) ELJP9_RS16960 ENOG4105D9M gamma-glutamylcysteine synthetase ELJP9_RS16965 ENOG4105W39 Membrane ELJP9_RS16970 ENOG4107VXZ Hydrolase ELJP9_RS17000 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) ELJP9_RS17005 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) ELJP9_RS17020 ENOG4107TH8 cina domain protein ELJP9_RS17025 ENOG4105DSE periplasmic solute binding protein ELJP9_RS17030 ENOG4105CC5 ABC transporter ELJP9_RS17035 ENOG4105DIK (ABC) transporter ELJP9_RS17040 ENOG4105CVE Lytic murein transglycosylase ELJP9_RS17045 ENOG410787A Pts system, glucitol sorbitol-specific ELJP9_RS17050 ENOG4105DZY Pts system, glucitol sorbitol-specific ELJP9_RS17055 ENOG4105VI0 Pts system, glucitol sorbitol-specific ELJP9_RS17060 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase ELJP9_RS17065 ENOG4105J92 DNA-binding transcriptional activator GutM ELJP9_RS17070 ENOG410804X Transcriptional regulator ELJP9_RS17080 ENOG4108JUA Transcriptional regulator ELJP9_RS17085 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center ELJP9_RS17090 ENOG4108EQM faD-dependent pyridine nucleotide-disulfide oxidoreductase ELJP9_RS17100 ENOG4105C8H hydrogenase maturation protein Hypf ELJP9_RS17105 ENOG4108RC0 Electron transport protein ELJP9_RS17110 ENOG4105DDV Transcriptional regulator (LacI family ELJP9_RS17115 ENOG4105C5Y PTS System ELJP9_RS17120 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS17125 ENOG4108MG9 hydrogenase 3 maturation protease ELJP9_RS17130 ENOG4105I6X formate hydrogenlyase maturation ELJP9_RS17135 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit ELJP9_RS17140 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit ELJP9_RS17145 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ELJP9_RS17150 ENOG4107TDF Formate hydrogenlyase subunit 4 ELJP9_RS17155 ENOG4107R30 NADH dehydrogenase ELJP9_RS17160 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) ELJP9_RS17165 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA ELJP9_RS17170 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) ELJP9_RS17175 ENOG4107RSS Hydrogenase accessory protein HypB ELJP9_RS17180 ENOG41083WG hydrogenase assembly chaperone ELJP9_RS17185 ENOG4105CQS hydrogenase expression formation protein HypD ELJP9_RS17190 ENOG4105C45 hydrogenase expression formation protein (HypE) ELJP9_RS17200 ENOG4105VXR cytoplasmic protein ELJP9_RS17215 ENOG4105KZM cytoplasmic protein ELJP9_RS17220 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) ELJP9_RS17225 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ELJP9_RS17235 ENOG4105JQN Transcriptional regulator ELJP9_RS17240 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS17255 ENOG4108K5P (LipO)protein ELJP9_RS17265 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) ELJP9_RS17270 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) ELJP9_RS17280 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) ELJP9_RS17285 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) ELJP9_RS17290 ENOG4105N0Z inner membrane protein ygbE ELJP9_RS17295 ENOG4107UCJ Catalyzes the synthesis of activated sulfate (By similarity) ELJP9_RS17305 ENOG4105C11 sulfate adenylyltransferase), subunit 2 ELJP9_RS17310 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ELJP9_RS17315 ENOG4108MXK alkaline phosphatase isozyme conversion ELJP9_RS17320 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) ELJP9_RS17325 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) ELJP9_RS17330 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ELJP9_RS17335 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase ELJP9_RS17340 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ELJP9_RS17350 ENOG4105CI1 PTS System ELJP9_RS17355 ENOG4105QEK Transcriptional regulator ELJP9_RS17365 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) ELJP9_RS17370 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) ELJP9_RS17375 ENOG4105DXN mazG family ELJP9_RS17380 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ELJP9_RS17385 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ELJP9_RS17390 ENOG4105BZU Histidine kinase ELJP9_RS17395 ENOG4105BZW Glycerate kinase ELJP9_RS17400 ENOG4105EQX glucarate dehydratase ELJP9_RS17405 ENOG4105EQX glucarate dehydratase ELJP9_RS17410 ENOG4105DJB Major Facilitator Superfamily ELJP9_RS17415 ENOG4105QDK Flavodoxin ELJP9_RS17420 ENOG4105DR9 pseudouridine synthase ELJP9_RS17425 ENOG4105WP7 tRNA pseudouridine synthase C ELJP9_RS17430 ENOG4108T6E Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity) ELJP9_RS17440 ENOG4105EWT decarboxylase family ELJP9_RS17445 ENOG4105C44 Serine transporter ELJP9_RS17450 ENOG4105EJQ L-serine dehydratase ELJP9_RS17455 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease ELJP9_RS17460 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) ELJP9_RS17465 ENOG4105M08 Membrane ELJP9_RS17470 ENOG4105ETT transcriptional Regulator, LysR family ELJP9_RS17475 ENOG4105M5B (LipO)protein ELJP9_RS17480 ENOG4105C9B Cysteine desulfurase ELJP9_RS17485 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) ELJP9_RS17490 ENOG4105CUZ uba thif-type nad fad binding protein ELJP9_RS17495 ENOG4105CA3 membrane-bound lytic murein transglycosylase ELJP9_RS17515 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ELJP9_RS17520 ENOG4107QZM n-acetylglutamate synthase ELJP9_RS17525 ENOG4107QYX exodeoxyribonuclease v alpha ELJP9_RS17530 ENOG4107QKA exodeoxyribonuclease V beta ELJP9_RS17535 ENOG4107QXK peptidase ELJP9_RS17540 ENOG4105DSY exodeoxyribonuclease V, gamma ELJP9_RS17545 ENOG4105RVB Prepilin peptidase dependent protein c ELJP9_RS17550 ENOG4105SEN Protein of unknown function (DUF2509) ELJP9_RS17555 ENOG4105JCS prepilin peptidase dependent protein ELJP9_RS17560 ENOG4105IPU prepilin peptidase dependent protein A ELJP9_RS17565 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) ELJP9_RS17570 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) ELJP9_RS17575 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase ELJP9_RS17580 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) ELJP9_RS17585 ENOG4105IRT Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity) ELJP9_RS17590 ENOG4105SUV lipoprotein YgdR ELJP9_RS17595 ENOG4105CPC Aldo Keto reductase ELJP9_RS17600 ENOG4107S74 Lysophospholipid transporter LplT ELJP9_RS17605 ENOG4105CEY Amp-dependent synthetase and ligase ELJP9_RS17610 ENOG41060NJ transcriptional regulator ELJP9_RS17620 ENOG4107YCY Transcriptional regulator ELJP9_RS17625 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS17635 ENOG4105DDV Transcriptional regulator (LacI family ELJP9_RS17645 ENOG4105RQF LysR family Transcriptional regulator ELJP9_RS17660 ENOG4108QY5 Ferric enterobactin transport protein ELJP9_RS17665 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component ELJP9_RS17670 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component ELJP9_RS17685 ENOG4107QNK )-transporter ELJP9_RS17690 ENOG4105CHR reductase ELJP9_RS17700 ENOG4105CAZ oligogalacturonide lyase ELJP9_RS17705 ENOG4108QGT oligogalacturonate-specific porin ELJP9_RS17715 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS17730 ENOG4108MHD transport protein ELJP9_RS17735 ENOG4105EW9 transcriptional regulator AsnC family ELJP9_RS17745 ENOG410830R acetyltransferase ELJP9_RS17750 ENOG4105VR1 Pfam:DUF1271 ELJP9_RS17755 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ELJP9_RS17760 ENOG4106YYS transcriptional regulatory protein ELJP9_RS17770 ENOG4105ECW sulfate abc transporter ELJP9_RS17775 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS17780 ENOG4105EIP mannose-6-phosphate isomerase ELJP9_RS17785 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS17795 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) ELJP9_RS17800 ENOG4105CK1 PTS System ELJP9_RS17805 ENOG4105VZJ PTS System ELJP9_RS17810 ENOG4105CK1 PTS System ELJP9_RS17815 ENOG4105VCP PTS System ELJP9_RS17820 ENOG4105DKQ ROK family ELJP9_RS17825 ENOG41060NJ transcriptional regulator ELJP9_RS17860 ENOG4108K5P (LipO)protein ELJP9_RS17865 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) ELJP9_RS17870 ENOG4105CRK lysyL-tRNA synthetase ELJP9_RS17880 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ELJP9_RS17885 ENOG4105T95 Thiol disulfide interChange protein ELJP9_RS17890 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ELJP9_RS17895 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) ELJP9_RS17900 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB ELJP9_RS17905 ENOG4105Y75 tpr repeat protein ELJP9_RS17910 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) ELJP9_RS17915 ENOG4108UT2 hemolysin iii ELJP9_RS17920 ENOG4108Q3X Transcriptional regulator ELJP9_RS17925 ENOG4105CS2 ec 3.2.1.21 ELJP9_RS17930 ENOG4105CYX Short-chain dehydrogenase reductase Sdr ELJP9_RS17935 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor ELJP9_RS17945 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) ELJP9_RS17950 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family ELJP9_RS17960 ENOG4107RAQ aminopeptidase ELJP9_RS17970 ENOG4107YUN Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) ELJP9_RS17980 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ELJP9_RS17985 ENOG4108JQ1 Dehydrogenase ELJP9_RS17990 ENOG4105E66 phosphoriboisomerase A ELJP9_RS17995 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) ELJP9_RS18000 ENOG4105MPN Membrane ELJP9_RS18005 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ELJP9_RS18015 ENOG4105D2N Aldolase ELJP9_RS18025 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ELJP9_RS18030 ENOG4105CV1 Transketolase (EC 2.2.1.1) ELJP9_RS18035 ENOG4108K0D peptidase, M48 ELJP9_RS18040 ENOG4105J5J Outer membrane porin ELJP9_RS18055 ENOG4108Q27 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity) ELJP9_RS18060 ENOG4105CHR reductase ELJP9_RS18065 ENOG410832A alpha/beta hydrolase fold ELJP9_RS18075 ENOG4105D94 Major Facilitator Superfamily ELJP9_RS18080 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase ELJP9_RS18090 ENOG4108FUF Transcriptional regulator, IclR family ELJP9_RS18095 ENOG4105CHR reductase ELJP9_RS18120 ENOG4105CYW agmatinase ELJP9_RS18125 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) ELJP9_RS18145 ENOG4107QNK )-transporter ELJP9_RS18150 ENOG4105GPY SprT protein ELJP9_RS18155 ENOG4105RWS endonuclease I ELJP9_RS18160 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ELJP9_RS18165 ENOG4105D7Z glutathione synthase ELJP9_RS18170 ENOG4108UJU UPF0301 protein ELJP9_RS18180 ENOG4105CZX twitching motility protein ELJP9_RS18185 ENOG4105DFA alanine racemase domain protein ELJP9_RS18190 ENOG4108VIA integral membrane protein ELJP9_RS18195 ENOG4105VZ9 UPF0235 protein ELJP9_RS18205 ENOG4105CSA Coproporphyrinogen iii oxidase ELJP9_RS18210 ENOG4105WDY DNA (cytosine-5-)-methyltransferase ELJP9_RS18215 ENOG4105K33 Periplasmic Protein ELJP9_RS18220 ENOG41090ED Protein with unknown function (DUF469) ELJP9_RS18230 ENOG4105CEN a g-specific adenine glycosylase ELJP9_RS18235 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) ELJP9_RS18240 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division ELJP9_RS18245 ENOG4105EAA nucleoside ELJP9_RS18250 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase ELJP9_RS18260 ENOG4105CHY citrate lyase, alpha ELJP9_RS18265 ENOG4105CI0 Citrate lyase ELJP9_RS18270 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) ELJP9_RS18275 ENOG4105DUA (citrate (pro-3S)-lyase ligase ELJP9_RS18280 ENOG4105ERH Fumarylacetoacetate hydrolase ELJP9_RS18285 ENOG4105D2K citrate carrier protein ELJP9_RS18290 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ELJP9_RS18295 ENOG4106YYS transcriptional regulatory protein ELJP9_RS18300 ENOG4105CXN decarboxylase ELJP9_RS18320 ENOG4108TUY outer membrane protein PgaA ELJP9_RS18325 ENOG4107BJW polysaccharide deacetylase ELJP9_RS18330 ENOG4105CND Glycosyl transferase, family 2 ELJP9_RS18340 ENOG4106032 Glutathionylspermidine synthase ELJP9_RS18345 ENOG4105CYM Glutathione S-transferase ELJP9_RS18355 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS18365 ENOG4105CPC Aldo Keto reductase ELJP9_RS18370 ENOG4108TEB UPF0114 protein ELJP9_RS18390 ENOG4108ZZF transport protein (ExbD) ELJP9_RS18395 ENOG4105CWK Biopolymer transport protein, ExbB ELJP9_RS18400 ENOG4105C28 cystathionine ELJP9_RS18405 ENOG4108K81 inner membrane protein YghB ELJP9_RS18410 ENOG4105CF7 AraC family transcriptional regulator ELJP9_RS18415 ENOG4108I6A alcohol dehydrogenase ELJP9_RS18420 ENOG4105CV8 reductase ELJP9_RS18425 ENOG4105CCT upf0313 protein ELJP9_RS18430 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) ELJP9_RS18435 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) ELJP9_RS18440 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase ELJP9_RS18445 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ELJP9_RS18450 ENOG4105H4F exported protein ELJP9_RS18455 ENOG4105XJC Two component transcriptional regulator (Winged helix family ELJP9_RS18460 ENOG4105DHQ Histidine kinase ELJP9_RS18465 ENOG4105NF4 modulator of drug activity ELJP9_RS18470 ENOG4105VRH Antibiotic biosynthesis monooxygenase ELJP9_RS18475 ENOG4105EP8 Glycosyl Hydrolase Family 88 ELJP9_RS18480 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) ELJP9_RS18490 ENOG4105W4W Transcriptional regulator ELJP9_RS18510 ENOG4105DQ5 transport system permease protein ELJP9_RS18515 ENOG4105E0A ABC, transporter ELJP9_RS18525 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ELJP9_RS18530 ENOG4105IPS esterase ELJP9_RS18535 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) ELJP9_RS18540 ENOG4108SX3 cytoplasmic protein ELJP9_RS18545 ENOG41087AY ADP-Ribose pyrophosphatase ELJP9_RS18555 ENOG4105F1G UPF0441 protein ELJP9_RS18560 ENOG4106032 Glutathionylspermidine synthase ELJP9_RS18565 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b ELJP9_RS18575 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) ELJP9_RS18580 ENOG4105W0Z cytoplasmic protein ELJP9_RS18585 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) ELJP9_RS18590 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) ELJP9_RS18595 ENOG4105I7R Adenylate cyclase ELJP9_RS18600 ENOG4106MWK domain protein ELJP9_RS18605 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate ELJP9_RS18615 ENOG4107ZVW dihydroneopterin aldolase ELJP9_RS18620 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) ELJP9_RS18625 ENOG4105C54 Major Facilitator superfamily ELJP9_RS18630 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) ELJP9_RS18635 ENOG4108YZ9 Urea amidohydrolase subunit gamma ELJP9_RS18640 ENOG4105KI2 Urea amidohydrolase subunit beta ELJP9_RS18645 ENOG4105CQM Urea amidohydrolase subunit alpha ELJP9_RS18650 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) ELJP9_RS18660 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) ELJP9_RS18665 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) ELJP9_RS18680 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ELJP9_RS18685 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ELJP9_RS18690 ENOG4108VCA G U mismatch-specific DNA glycosylase ELJP9_RS18735 ENOG4105ZTC transcriptional activator, Ogr delta ELJP9_RS18775 ENOG4105UZW Tail fiber assembly protein ELJP9_RS18780 ENOG4108X9F tail fiber protein ELJP9_RS18840 ENOG4105VZ1 Replication Protein ELJP9_RS18845 ENOG4105KSC Transcriptional regulator, TraR DksA family ELJP9_RS18870 ENOG4105Q26 Siderophore-interacting protein ELJP9_RS18875 ENOG4105NTW Transcriptional regulator ELJP9_RS18880 ENOG4105C8Q Methyl-accepting chemotaxis ELJP9_RS18885 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor ELJP9_RS18890 ENOG4105C8Y Acetylornithine aminotransferase ELJP9_RS18905 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ELJP9_RS18910 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound ELJP9_RS18915 ENOG41061GT Aldolase ELJP9_RS18920 ENOG4105D4B ABC, transporter ELJP9_RS18925 ENOG4105F5R ABC transporter ELJP9_RS18930 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane ELJP9_RS18935 ENOG4105C2J ABC transporter ELJP9_RS18940 ENOG4105DKT Transcriptional regulator ELJP9_RS18945 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) ELJP9_RS18950 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ELJP9_RS18955 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) ELJP9_RS18960 ENOG4108VKG metal-dependent hydrolase ELJP9_RS18965 ENOG4105EE0 oxidoreductase ELJP9_RS18970 ENOG4105DU1 integral membrane protein, terc ELJP9_RS18980 ENOG4105CTX dehydratase ELJP9_RS18990 ENOG4105DPW Major facilitator superfamily MFS_1 ELJP9_RS18995 ENOG4107YCY Transcriptional regulator ELJP9_RS19000 ENOG4106W5V Membrane ELJP9_RS19005 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) ELJP9_RS19010 ENOG4105WAY exported protein ELJP9_RS19015 ENOG4105NE1 Conserved Protein ELJP9_RS19020 ENOG41090KG Inner membrane protein YqjE ELJP9_RS19025 ENOG4105YJD ELJP9_RS19030 ENOG4108VBZ doxx family ELJP9_RS19035 ENOG4105CHF Glutathione S-transferase ELJP9_RS19040 ENOG4105KAF membrAne ELJP9_RS19045 ENOG4105CWB LysR family transcriptional Regulator ELJP9_RS19050 ENOG4108CNN domain protein ELJP9_RS19060 ENOG4105C44 Serine transporter ELJP9_RS19070 ENOG4105C6N Formate acetyltransferase ELJP9_RS19075 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ELJP9_RS19080 ENOG4108MST Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity) ELJP9_RS19085 ENOG4105C7B Threonine dehydratase ELJP9_RS19090 ENOG410811B TRANSCRIPTIONal ELJP9_RS19100 ENOG4105BZW Glycerate kinase ELJP9_RS19105 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ELJP9_RS19110 ENOG4105CNV Aldolase ELJP9_RS19115 ENOG4105CTX dehydratase ELJP9_RS19120 ENOG4105E98 transcriptional regulator DeoR family ELJP9_RS19125 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of ELJP9_RS19130 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB ELJP9_RS19140 ENOG4105F3R pts system mannose fructose sorbose family iid ELJP9_RS19145 ENOG4108YTN IIa component ELJP9_RS19150 ENOG4105CE4 GlcNAc 6-P deacetylase ELJP9_RS19155 ENOG4105E70 isomerase ELJP9_RS19160 ENOG4105D2N Aldolase ELJP9_RS19165 ENOG4105CI1 PTS System ELJP9_RS19170 ENOG4105C87 Aminotransferase class I and II ELJP9_RS19180 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ELJP9_RS19185 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) ELJP9_RS19190 ENOG41082RQ UPF0102 protein ELJP9_RS19195 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) ELJP9_RS19200 ENOG4105W4M Transport-associated protein ELJP9_RS19210 ENOG4105K4T epimerase ELJP9_RS19215 ENOG4107R7Y intracellular protease Pfpi family ELJP9_RS19220 ENOG4108ZPB UPF0306 protein ELJP9_RS19225 ENOG41082IR Excinuclease ABC C subunit domain protein ELJP9_RS19230 ENOG4108YYD acetyltransferase ELJP9_RS19250 ENOG4105DEN Luciferase family ELJP9_RS19255 ENOG4105CIC tryptophan-specific transport protein ELJP9_RS19260 ENOG4105C1J atp-dependent rna helicase ELJP9_RS19275 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) ELJP9_RS19280 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) ELJP9_RS19285 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) ELJP9_RS19290 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) ELJP9_RS19295 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) ELJP9_RS19300 ENOG4105CHV Transcription elongation factor NusA ELJP9_RS19305 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) ELJP9_RS19315 ENOG4105CDH Citrulline--aspartate ligase ELJP9_RS19325 ENOG4105NTZ Preprotein translocase subunit SecG ELJP9_RS19330 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) ELJP9_RS19335 ENOG4105EEI dihydropteroate synthase ELJP9_RS19340 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ELJP9_RS19345 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) ELJP9_RS19350 ENOG4105HBR Rna-binding protein ELJP9_RS19355 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) ELJP9_RS19360 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase ELJP9_RS19375 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control ELJP9_RS19380 ENOG4105QYV Membrane ELJP9_RS19385 ENOG4105K46 50S ribosomal protein l27 ELJP9_RS19390 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) ELJP9_RS19395 ENOG4105EAH synthase ELJP9_RS19400 ENOG4105HVQ Regulatory factor of maltose metabolism ELJP9_RS19405 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ELJP9_RS19410 ENOG4105VFK BolA family ELJP9_RS19415 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane ELJP9_RS19420 ENOG4105E3I toluene tolerance ELJP9_RS19425 ENOG4107PE3 Mammalian cell entry related domain protein ELJP9_RS19430 ENOG4105CY3 ABC transporter, permease ELJP9_RS19435 ENOG4105DHJ ABC, transporter ELJP9_RS19445 ENOG4105C2X Arabinose 5-phosphate isomerase ELJP9_RS19450 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase ELJP9_RS19455 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) ELJP9_RS19460 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA ELJP9_RS19465 ENOG4108IUZ ABC transporter ELJP9_RS19470 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ELJP9_RS19475 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA ELJP9_RS19480 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN ELJP9_RS19485 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) ELJP9_RS19490 ENOG41080Z8 PHOSPHOCARRIER protein ELJP9_RS19495 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase ELJP9_RS19500 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain ELJP9_RS19505 ENOG4105BZU Histidine kinase ELJP9_RS19510 ENOG4108K5H permease YjgP YjgQ family protein ELJP9_RS19515 ENOG4108M8S permease YjgP YjgQ family protein ELJP9_RS19520 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) ELJP9_RS19525 ENOG4105MYG DNA polymerase iii, chi subunit ELJP9_RS19535 ENOG4108MJ3 acetyltransferase ELJP9_RS19540 ENOG4105DQ4 alcohol dehydrogenase ELJP9_RS19550 ENOG4105D7A ATP-binding protein ELJP9_RS19555 ENOG4105N5T Radical SAM Protein ELJP9_RS19560 ENOG4105CBC glutamate synthase ELJP9_RS19565 ENOG4105BZ8 glutamate synthase ELJP9_RS19575 ENOG4105E6S usher protein( ELJP9_RS19580 ENOG4108S1B Periplasmic chaperone protein ELJP9_RS19585 ENOG4105UMR response to DNA damage stimulus ELJP9_RS19590 ENOG4105KB2 stringent starvation protein b ELJP9_RS19595 ENOG4107MKT Stringent starvation protein a ELJP9_RS19605 ENOG4108UJD 30S ribosomal protein S9 ELJP9_RS19615 ENOG4105D6Z AFG1 family ATPase ELJP9_RS19620 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III ELJP9_RS19625 ENOG4105C0H protease ELJP9_RS19630 ENOG4105C0H protease ELJP9_RS19635 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) ELJP9_RS19645 ENOG4105RID UPF0379 protein yhcN ELJP9_RS19650 ENOG4105RID UPF0379 protein yhcN ELJP9_RS19655 ENOG4105UNR (Barnase) inhibitor ELJP9_RS19660 ENOG4105C26 Dehydrogenase ELJP9_RS19665 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) ELJP9_RS19675 ENOG4105ZQC membrane protein AaeX ELJP9_RS19685 ENOG4105R3P Inner membrane protein yagU ELJP9_RS19690 ENOG4105D1U peptidase U62 modulator of DNA gyrase ELJP9_RS19695 ENOG4105QD6 exported protein ELJP9_RS19700 ENOG4105C03 ribonuclease ELJP9_RS19710 ENOG4105VQ7 Rod shape-determining protein MreD ELJP9_RS19715 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ELJP9_RS19725 ENOG41062P1 Diguanylate cyclase phosphodiesterase ELJP9_RS19730 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family ELJP9_RS19740 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) ELJP9_RS19745 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) ELJP9_RS19750 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein ELJP9_RS19755 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ELJP9_RS19760 ENOG4105RG0 Membrane ELJP9_RS19765 ENOG4108IA2 Sodium pantothenate symporter ELJP9_RS19780 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ELJP9_RS19790 ENOG41061ME transport protein ELJP9_RS19795 ENOG4105BZU Histidine kinase ELJP9_RS19800 ENOG4108XG4 DNA-binding transcriptional regulator ELJP9_RS19810 ENOG4105BZS acriflavin resistance protein ELJP9_RS19815 ENOG4105XCM membrane LIPOPROTEIN ELJP9_RS19825 ENOG4105EZ7 amino acid ABC transporter ELJP9_RS19830 ENOG4105DRP amino acid AbC transporter ELJP9_RS19835 ENOG4105CDA abc transporter atp-binding protein ELJP9_RS19870 ENOG4108Z0R Transferase ELJP9_RS19875 ENOG4105SG3 Protein of unknown function (DUF1488) ELJP9_RS19880 ENOG4105E2X shikimate dehydrogenase ELJP9_RS19885 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ELJP9_RS19890 ENOG4108WI1 Dna topoisomerase ELJP9_RS19895 ENOG4108RPN Protein smg homolog ELJP9_RS19900 ENOG4105C79 DNA protecting protein DprA ELJP9_RS19905 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ELJP9_RS19910 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) ELJP9_RS19915 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ELJP9_RS19920 ENOG4105C1A potassium transporter peripheral membrane ELJP9_RS19925 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) ELJP9_RS19930 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system ELJP9_RS19935 ENOG4105W1Y Transcriptional regulator ELJP9_RS19940 ENOG4105VTS DnaJ-like, subfamily C ELJP9_RS19945 ENOG4108ZT0 50S ribosomal protein l17 ELJP9_RS19950 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ELJP9_RS19955 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) ELJP9_RS19960 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) ELJP9_RS19970 ENOG41067V7 50S ribosomal protein L36 ELJP9_RS19975 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ELJP9_RS19985 ENOG4105VPB 50S ribosomal protein L30 ELJP9_RS19995 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) ELJP9_RS20000 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) ELJP9_RS20005 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) ELJP9_RS20010 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) ELJP9_RS20020 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) ELJP9_RS20025 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) ELJP9_RS20030 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal ELJP9_RS20035 ENOG41083MP 50s ribosomal protein l29 ELJP9_RS20040 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) ELJP9_RS20050 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) ELJP9_RS20090 ENOG4108UQY Iron-storage protein ELJP9_RS20095 ENOG4105W53 bacterioferritin-associated ferredoxin ELJP9_RS20100 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) ELJP9_RS20105 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) ELJP9_RS20120 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) ELJP9_RS20125 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) ELJP9_RS20130 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) ELJP9_RS20135 ENOG4105WWK YheO domain protein ELJP9_RS20140 ENOG4108V1T peptidylprolyl cis-trans isomerase ELJP9_RS20145 ENOG4105VRX Protein slyX homolog ELJP9_RS20150 ENOG4108YZY peptidylprolyl cis-trans isomerase ELJP9_RS20155 ENOG4105VKU nucleicacid-binding protein ELJP9_RS20160 ENOG4105CKD glutathione-regulated potassium-efflux system protein ELJP9_RS20165 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ELJP9_RS20170 ENOG4105C5H ABC transporter ELJP9_RS20175 ENOG4108K70 Transcriptional regulator ELJP9_RS20180 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ELJP9_RS20190 ENOG4107TT2 Auxin Efflux Carrier ELJP9_RS20220 ENOG4105DNZ Alpha Beta Hydrolase ELJP9_RS20225 ENOG4105YP7 UPF0270 protein ELJP9_RS20230 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) ELJP9_RS20235 ENOG4108UKZ OsmC family ELJP9_RS20240 ENOG4107RYR Transcriptional regulator, Crp Fnr family ELJP9_RS20245 ENOG410613R integral membrane protein, YccS YhfK family ELJP9_RS20250 ENOG4105C8Y Acetylornithine aminotransferase ELJP9_RS20255 ENOG4105DDQ anthranilate synthase ELJP9_RS20260 ENOG4105MZU cell filamentation protein ELJP9_RS20270 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) ELJP9_RS20275 ENOG4106DTQ Protein TsgA homolog ELJP9_RS20280 ENOG4105DZC cytosine deaminase ELJP9_RS20285 ENOG4107QZF nitrite reductase NADPH large subunit ELJP9_RS20290 ENOG4105WZK nitrite reductase NADPH small subunit ELJP9_RS20295 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ELJP9_RS20300 ENOG4105VYH ELJP9_RS20305 ENOG4105C31 Tryptophanyl-tRNA synthetase ELJP9_RS20315 ENOG4105DJV ribulose-phosphate 3-epimerase ELJP9_RS20320 ENOG4105DFE Dna adenine methylase ELJP9_RS20325 ENOG4105EGB membrane protein DamX ELJP9_RS20330 ENOG4105D49 3-dehydroquinate synthase ELJP9_RS20335 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) ELJP9_RS20345 ENOG4105ITY Required for the use of extracellular DNA as a nutrient ELJP9_RS20350 ENOG4105XPX DNA utilization protein HofO ELJP9_RS20365 ENOG4108JQC penicillin-binding protein 1A ELJP9_RS20370 ENOG4107RK2 ADP-ribose diphosphatase NudE ELJP9_RS20375 ENOG4105DQY intracellular growth attenuator ELJP9_RS20380 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 ELJP9_RS20385 ENOG4105VEJ Heat shock protein ELJP9_RS20390 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) ELJP9_RS20395 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase ELJP9_RS20400 ENOG4105E0F Histidine kinase ELJP9_RS20410 ENOG4108RRZ Transcription elongation factor GreB ELJP9_RS20415 ENOG4105BZM domain protein ELJP9_RS20420 ENOG4105XFK Ferrous iron transport protein A ELJP9_RS20425 ENOG4105CE1 Ferrous iron transport protein b ELJP9_RS20430 ENOG41060N5 May function as a transcriptional regulator that controls feoABC expression (By similarity) ELJP9_RS20445 ENOG4105MJ2 Competence protein ELJP9_RS20450 ENOG4107RUK Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity) ELJP9_RS20455 ENOG4105C6Z Gluconate ELJP9_RS20460 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) ELJP9_RS20465 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) ELJP9_RS20470 ENOG41061ZR Transcriptional regulator ELJP9_RS20475 ENOG4105E98 transcriptional regulator DeoR family ELJP9_RS20480 ENOG4105EBW Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity) ELJP9_RS20485 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) ELJP9_RS20490 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ELJP9_RS20495 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) ELJP9_RS20500 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) ELJP9_RS20505 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) ELJP9_RS20510 ENOG4108ESZ Glycogen debranching enzyme ELJP9_RS20515 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) ELJP9_RS20520 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ELJP9_RS20525 ENOG41076UM multiple antibiotic resistance (MarC)-related protein ELJP9_RS20530 ENOG4105C6Z Gluconate ELJP9_RS20535 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family ELJP9_RS20540 ENOG4105DIQ Transcriptional regulator ELJP9_RS20545 ENOG4105C2I pirin domain protein ELJP9_RS20550 ENOG4105D9R oxidoreductase ELJP9_RS20560 ENOG4105WCN acetyltransferase ELJP9_RS20565 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) ELJP9_RS20570 ENOG4105WC8 Conserved Protein ELJP9_RS20575 ENOG4107T6V glycerophosphoryl diester phosphodiesterase ELJP9_RS20590 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component ELJP9_RS20595 ENOG4105BZ7 extracellular solute-binding protein family 1 ELJP9_RS20600 ENOG4108IV0 ABC, transporter ELJP9_RS20605 ENOG4105C0Z ABC transporter ELJP9_RS20610 ENOG4105CF8 branched-chain amino acid ABC transporter, permease ELJP9_RS20615 ENOG4105C32 Amino acid ABC transporter (Permease) ELJP9_RS20620 ENOG4105CP9 extracellular ligand-binding receptor ELJP9_RS20630 ENOG4105U59 -acetyltransferase ELJP9_RS20635 ENOG4105CP9 extracellular ligand-binding receptor ELJP9_RS20640 ENOG4108JPW Aminotransferase ELJP9_RS20645 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ELJP9_RS20650 ENOG4105CRP Part of the ABC transporter FtsEX involved in ELJP9_RS20655 ENOG4105CAK Cell division ATP-binding protein ftsE ELJP9_RS20660 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ELJP9_RS20665 ENOG4106H78 methyltransferase ELJP9_RS20680 ENOG4107FS9 Membrane ELJP9_RS20685 ENOG4105C59 p-type ATPase ELJP9_RS20690 ENOG4105CG6 trap dicarboxylate transporter dctm subunit ELJP9_RS20705 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) ELJP9_RS20710 ENOG4105EX9 Membrane ELJP9_RS20715 ENOG4108W1V Lipoprotein ELJP9_RS20720 ENOG4105F9N Major Facilitator Superfamily ELJP9_RS20725 ENOG4105DSF transport protein ELJP9_RS20775 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) ELJP9_RS20810 ENOG4105C2D reductase ELJP9_RS20815 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ELJP9_RS20820 ENOG4107YAK holo-(acyl carrier protein) synthase 2 ELJP9_RS20825 ENOG4105PE8 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) ELJP9_RS20835 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) ELJP9_RS20840 ENOG4105F73 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) ELJP9_RS20845 ENOG4105C3I Nad-dependent epimerase dehydratase ELJP9_RS20850 ENOG4105CKK Glycosyl transferase, family 2 ELJP9_RS20860 ENOG4105PY6 Phenolic acid decarboxylase ELJP9_RS20865 ENOG4105ETT transcriptional Regulator, LysR family ELJP9_RS20870 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ELJP9_RS20875 ENOG4107TT5 NLP P60 protein ELJP9_RS20900 ENOG4107258 Transcriptional regulator ELJP9_RS20905 ENOG4105JSC dimethylmenaquinone methyltransferase ELJP9_RS20915 ENOG4105CBX hi0933 family ELJP9_RS20920 ENOG4105CJ3 phosphate transporter ELJP9_RS20925 ENOG4108V6B universal stress protein B ELJP9_RS20935 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) ELJP9_RS20940 ENOG4105DGW oligopeptidase A ELJP9_RS20945 ENOG4105D6S protein involved in catabolism of external DNA ELJP9_RS20950 ENOG4105DC8 reductase ELJP9_RS20975 ENOG4106S2D Transcriptional regulator ELJP9_RS20980 ENOG4105CHR reductase ELJP9_RS20985 ENOG4105CBN LysR family transcriptional regulator ELJP9_RS20990 ENOG4107H3J ribonuclease ELJP9_RS20995 ENOG4105CSH Transporter ELJP9_RS21000 ENOG41066T0 asmA family ELJP9_RS21005 ENOG4105CMB EAL domain-containing protein ELJP9_RS21015 ENOG4105CS0 peptidase ELJP9_RS21020 ENOG4105CK2 sodium dicarboxylate symporter ELJP9_RS21025 ENOG4105BZU Histidine kinase ELJP9_RS21030 ENOG4105EJG cellulose synthase ELJP9_RS21035 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) ELJP9_RS21040 ENOG4107EEX Cellulose synthase regulator protein ELJP9_RS21045 ENOG4107QZ7 Cellulose synthase catalytic subunit ELJP9_RS21055 ENOG410661M cytoplasmic protein ELJP9_RS21060 ENOG4105U74 cellulose biosynthesis protein BcsE ELJP9_RS21065 ENOG410675P Celllulose biosynthesis operon protein BcsF YhjT ELJP9_RS21070 ENOG4105D1V cellulose synthase operon protein YhjU ELJP9_RS21080 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase ELJP9_RS21085 ENOG4105D4A Cell wall formation (By similarity) ELJP9_RS21115 ENOG4108RR8 protoporphyrinogen oxidase ELJP9_RS21120 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) ELJP9_RS21125 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein ELJP9_RS21130 ENOG4105D9Y Splits dipeptides with a prolyl residue in the C- terminal position (By similarity) ELJP9_RS21135 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ELJP9_RS21140 ENOG4105CHU acetyl-coa acetyltransferase ELJP9_RS21145 ENOG4107QK7 reductase ELJP9_RS21150 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) ELJP9_RS21155 ENOG4105MDZ Transcriptional activator rfaH ELJP9_RS21160 ENOG4105F8V Hydrolase, tatD family ELJP9_RS21165 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ELJP9_RS21170 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) ELJP9_RS21175 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) ELJP9_RS21180 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) ELJP9_RS21185 ENOG4105JC1 sterol-binding domain protein ELJP9_RS21190 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ELJP9_RS21195 ENOG4105CGY Dna recombination protein ELJP9_RS21200 ENOG4107SXA Phosphorylase ELJP9_RS21205 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) ELJP9_RS21215 ENOG4105DZ2 Transcriptional regulator ELJP9_RS21220 ENOG4105EMK carboxylate amino acid amine transporter ELJP9_RS21225 ENOG4105DQF Hydrolase ELJP9_RS21230 ENOG4108EUD Lysophospholipase ELJP9_RS21235 ENOG410829K Lysine exporter protein (Lyse ygga) ELJP9_RS21240 ENOG4105CCF Lysine exporter protein (Lyse ygga) ELJP9_RS21245 ENOG4105C9U ATP-dependent DNA helicase RecQ ELJP9_RS21250 ENOG4105HDD phospholipase ELJP9_RS21255 ENOG4108VUY thioesterase Superfamily protein ELJP9_RS21260 ENOG4105FR1 rard protein ELJP9_RS21265 ENOG4107QUT magnesium and cobalt transport protein CorA ELJP9_RS21270 ENOG4105C4R Atp-dependent dna helicase ELJP9_RS21275 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant ELJP9_RS21280 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ELJP9_RS21285 ENOG4105CT0 Protein of unknown function, DUF484 ELJP9_RS21295 ENOG4105S7Z (LipO)protein ELJP9_RS21305 ENOG4107T0K Adenylate cyclase ELJP9_RS21310 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) ELJP9_RS21315 ENOG41076E6 Uroporphyrinogen-III Synthase ELJP9_RS21320 ENOG4105ECF c-methyltransferase ELJP9_RS21325 ENOG410601J HemY protein ELJP9_RS21360 ENOG4105C85 amino acid ELJP9_RS21365 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family ELJP9_RS21370 ENOG4105DAD Could be involved in ECA polysaccharide chain elongation (By similarity) ELJP9_RS21375 ENOG4105F18 Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity) ELJP9_RS21380 ENOG4105EGZ biosynthesis protein ELJP9_RS21385 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ELJP9_RS21390 ENOG4108WJ1 acetyltransferase ELJP9_RS21395 ENOG4107QQG Dehydrogenase ELJP9_RS21400 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ELJP9_RS21405 ENOG4105SFE lipopolysaccharide biosynthesis protein ELJP9_RS21410 ENOG4105ESV Glycosyl transferase, family 4 ELJP9_RS21415 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ELJP9_RS21430 ENOG4105C9X ppx gppa phosphatase ELJP9_RS21435 ENOG4105C4R Atp-dependent dna helicase ELJP9_RS21440 ENOG4105KQ5 peptidylprolyl cis-trans isomerase ELJP9_RS21445 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase ELJP9_RS21450 ENOG4105EMY transcriptional regulator ELJP9_RS21455 ENOG4105C7B Threonine dehydratase ELJP9_RS21465 ENOG4105CM2 brancheD-chain amino acid aminotransferase ELJP9_RS21470 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit ELJP9_RS21490 ENOG4105C0P Mg chelatase subunit ChlI ELJP9_RS21495 ENOG4108WFC UPF0438 protein yifE ELJP9_RS21545 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) ELJP9_RS21550 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) ELJP9_RS21555 ENOG4108Y73 Membrane ELJP9_RS21560 ENOG4105EJ2 Transcriptional regulator ELJP9_RS21570 ENOG4105C5Q Transcriptional regulator ELJP9_RS21575 ENOG4105CH7 arginosuccinase ELJP9_RS21580 ENOG4105CAS nag kinase ELJP9_RS21585 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase ELJP9_RS21590 ENOG4105CWC Acetylornithine deacetylase ELJP9_RS21595 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) ELJP9_RS21600 ENOG4106R3P AraC family transcriptional regulator ELJP9_RS21605 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ELJP9_RS21610 ENOG4105DCT glycerol dehydrogenase ELJP9_RS21615 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) ELJP9_RS21620 ENOG4105SYT Methylenetetrahydrofolate reductase ELJP9_RS21625 ENOG4105CFH Aspartokinase ELJP9_RS21630 ENOG4105C28 cystathionine ELJP9_RS21640 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) ELJP9_RS21645 ENOG4105VFB Binds the 23S rRNA (By similarity) ELJP9_RS21650 ENOG4105C25 Primosomal protein n' ELJP9_RS21655 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS21660 ENOG41063M6 Cell Division Protein ELJP9_RS21665 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) ELJP9_RS21675 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ELJP9_RS21685 ENOG4105N4M Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) ELJP9_RS21690 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ELJP9_RS21695 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) ELJP9_RS21700 ENOG4105CBT Fructose-1,6-bisphosphatase ELJP9_RS21705 ENOG4105DP0 ferredoxin-NADP reductase ELJP9_RS21710 ENOG4108VTS Membrane ELJP9_RS21715 ENOG4105EBK exported protein ELJP9_RS21720 ENOG4105CP7 Triose-phosphate isomerase ELJP9_RS21730 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) ELJP9_RS21735 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ELJP9_RS21740 ENOG4105CTQ phosphohexokinase ELJP9_RS21745 ENOG41076HS cation diffusion facilitator family transporter ELJP9_RS21750 ENOG4105FMW periplasmic ELJP9_RS21755 ENOG4105E3W Two component transcriptional regulator (Winged helix family ELJP9_RS21760 ENOG4105E0F Histidine kinase ELJP9_RS21765 ENOG4108RPX mosc domain containing protein ELJP9_RS21770 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ELJP9_RS21775 ENOG4107YRA Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity) ELJP9_RS21780 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) ELJP9_RS21785 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) ELJP9_RS21795 ENOG4105DET Rhamnulokinase ELJP9_RS21800 ENOG4105DKG l-rhamnose isomerase ELJP9_RS21815 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) ELJP9_RS21835 ENOG4108UMN azlc family ELJP9_RS21860 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein ELJP9_RS21865 ENOG4108MG3 formate dehydrogenase ELJP9_RS21870 ENOG4105F46 Necessary for formate dehydrogenase activity (By similarity) ELJP9_RS21880 ENOG4105SUU thioesterase domain ELJP9_RS21890 ENOG4107S2Z UPF0761 membrane protein ELJP9_RS21895 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 ELJP9_RS21900 ENOG4105E98 transcriptional regulator DeoR family ELJP9_RS21905 ENOG4108MGF sugar kinase ELJP9_RS21910 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ELJP9_RS21915 ENOG4105D2M Aldolase ELJP9_RS21920 ENOG4107QKS N-acylglucosamine 2-epimerase ELJP9_RS21925 ENOG4105CJQ hydrolase, family 31 ELJP9_RS21930 ENOG4105CT4 transporter ELJP9_RS21940 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is ELJP9_RS21945 ENOG4105CI3 gtp-binding protein typa ELJP9_RS21950 ENOG4105C5F glutamine synthetase ELJP9_RS21955 ENOG4105CUX Signal transduction histidine kinase ELJP9_RS21960 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ELJP9_RS21965 ENOG4106FIY ELJP9_RS21970 ENOG4105D4P Coproporphyrinogen iii oxidase ELJP9_RS21980 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) ELJP9_RS21995 ENOG4106HNH Acyl-transferase ELJP9_RS22000 ENOG4108Z33 Thiol disulfide Interchange Protein ELJP9_RS22005 ENOG4105E27 serine threonine protein kinase ELJP9_RS22010 ENOG4105PC1 Conserved Protein ELJP9_RS22015 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) ELJP9_RS22020 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b ELJP9_RS22045 ENOG4107EJG GntR family transcriptional regulator ELJP9_RS22050 ENOG4105C0R drug resistance transporter emrb qaca subfamily ELJP9_RS22055 ENOG4105ETE Transcriptional regulator (LacI family ELJP9_RS22060 ENOG4108RVA ribokinase ELJP9_RS22065 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ELJP9_RS22070 ENOG4105CNN ABC, transporter ELJP9_RS22075 ENOG4105C2J ABC transporter ELJP9_RS22080 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) ELJP9_RS22085 ENOG4105DFH Transport of potassium into the cell (By similarity) ELJP9_RS22095 ENOG4105EV2 VWA domain protein interacting with AAA ATPase ELJP9_RS22100 ENOG4105CU9 asparagine synthetase A ELJP9_RS22105 ENOG4108VVK transcriptional Regulator, AsnC ELJP9_RS22110 ENOG4105QTB Flavodoxin ELJP9_RS22115 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) ELJP9_RS22120 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) ELJP9_RS22125 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation ELJP9_RS22130 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) ELJP9_RS22140 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) ELJP9_RS22145 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) ELJP9_RS22150 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) ELJP9_RS22160 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) ELJP9_RS22165 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) ELJP9_RS22170 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) ELJP9_RS22175 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ELJP9_RS22180 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) ELJP9_RS22185 ENOG4105C8U phosphate abc transporter ELJP9_RS22190 ENOG4105E2Z phosphate ABC transporter (Permease ELJP9_RS22195 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ELJP9_RS22205 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 ELJP9_RS22210 ENOG4105C7N Xanthine uracil vitamin C permease ELJP9_RS22215 ENOG4108YYH Nadph-dependent fmn reductase ELJP9_RS22220 ENOG4105E8Q phosphopantetheinyl transferase ELJP9_RS22225 ENOG4105G2Y Transcriptional regulator ELJP9_RS22230 ENOG4105CNH Multidrug resistance protein MdtL ELJP9_RS22235 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) ELJP9_RS22240 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ELJP9_RS22250 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) ELJP9_RS22255 ENOG4105VG0 50S ribosomal protein l34