locus-tag	class	description
HWQ15_RS00005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HWQ15_RS00010	COG1091	dTDP-4-dehydrorhamnose reductase activity
HWQ15_RS00015	COG1088	dTDP-glucose 4,6-dehydratase activity
HWQ15_RS00030	COG0438	transferase activity, transferring glycosyl groups
HWQ15_RS00035	COG2327	Polysaccharide pyruvyl transferase
HWQ15_RS00040	COG2244	polysaccharide biosynthetic process
HWQ15_RS00045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HWQ15_RS00050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HWQ15_RS00060	COG0297	glycogen (starch) synthase activity
HWQ15_RS00065	COG1051	belongs to the nudix hydrolase family
HWQ15_RS00070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HWQ15_RS00075	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HWQ15_RS00080	COG0110	maltose O-acetyltransferase activity
HWQ15_RS00085	COG1216	Glycosyl transferase, family 2
HWQ15_RS00095	COG0438	transferase activity, transferring glycosyl groups
HWQ15_RS00100	COG1045	serine acetyltransferase
HWQ15_RS00105	COG0463	Glycosyl transferase, family 2
HWQ15_RS00110	COG0489	protein tyrosine kinase activity
HWQ15_RS00110	COG3206	protein involved in exopolysaccharide biosynthesis
HWQ15_RS00125	COG1253	flavin adenine dinucleotide binding
HWQ15_RS00130	COG2982	Protein involved in outer membrane biogenesis
HWQ15_RS00135	COG0717	Belongs to the dCTP deaminase family
HWQ15_RS00145	COG5002	protein histidine kinase activity
HWQ15_RS00145	COG5001	Diguanylate cyclase
HWQ15_RS00145	COG3447	MASE1 domain protein
HWQ15_RS00150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HWQ15_RS00155	COG0443	Heat shock 70 kDa protein
HWQ15_RS00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS00165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS00170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS00175	COG0477	Major facilitator Superfamily
HWQ15_RS00180	COG2205	protein histidine kinase activity
HWQ15_RS00185	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS00205	COG1597	lipid kinase activity
HWQ15_RS00210	COG1830	Aldolase
HWQ15_RS00215	COG2211	Major facilitator Superfamily
HWQ15_RS00220	COG1397	ADP-ribosylglycohydrolase
HWQ15_RS00225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HWQ15_RS00230	COG2188	Transcriptional regulator
HWQ15_RS00235	COG0351	phosphomethylpyrimidine kinase
HWQ15_RS00240	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HWQ15_RS00255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HWQ15_RS00260	COG0076	glutamate decarboxylase activity
HWQ15_RS00265	COG0489	protein tyrosine kinase activity
HWQ15_RS00265	COG3206	protein involved in exopolysaccharide biosynthesis
HWQ15_RS00270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HWQ15_RS00275	COG1596	polysaccharide export
HWQ15_RS00280	COG5455	response to cobalt ion
HWQ15_RS00290	COG0489	protein tyrosine kinase activity
HWQ15_RS00300	COG4807	Protein conserved in bacteria
HWQ15_RS00305	COG3279	Response regulator of the LytR AlgR family
HWQ15_RS00310	COG3275	phosphorelay sensor kinase activity
HWQ15_RS00315	COG0789	Transcriptional regulator
HWQ15_RS00325	COG1174	glycine betaine transport
HWQ15_RS00330	COG1125	glycine betaine transport
HWQ15_RS00335	COG1174	glycine betaine transport
HWQ15_RS00340	COG1732	Glycine betaine
HWQ15_RS00345	COG1472	Belongs to the glycosyl hydrolase 3 family
HWQ15_RS00350	COG0277	FAD linked oxidase domain protein
HWQ15_RS00360	COG1686	Belongs to the peptidase S11 family
HWQ15_RS00370	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS00375	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS00380	COG1538	Outer membrane efflux protein
HWQ15_RS00390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HWQ15_RS00400	COG1346	cytolysis
HWQ15_RS00405	COG0295	cytidine deaminase activity
HWQ15_RS00410	COG2949	membrane
HWQ15_RS00420	COG1129	ABC transporter
HWQ15_RS00435	COG2311	Membrane
HWQ15_RS00445	COG0477	Major facilitator Superfamily
HWQ15_RS00450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HWQ15_RS00455	COG4771	TonB-dependent receptor
HWQ15_RS00460	COG0833	amino acid
HWQ15_RS00465	COG0583	DNA-binding transcription factor activity
HWQ15_RS00470	COG2855	membrane
HWQ15_RS00475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HWQ15_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HWQ15_RS00480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HWQ15_RS00480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HWQ15_RS00485	COG1105	Belongs to the carbohydrate kinase PfkB family
HWQ15_RS00505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HWQ15_RS00510	COG1312	Catalyzes the dehydration of D-mannonate
HWQ15_RS00515	COG0246	Mannitol dehydrogenase
HWQ15_RS00520	COG0523	cobalamin synthesis protein
HWQ15_RS00525	COG0671	phosphoesterase, PA-phosphatase related
HWQ15_RS00530	COG0791	NLP P60 protein
HWQ15_RS00535	COG2200	EAL domain
HWQ15_RS00540	COG4166	transmembrane transport
HWQ15_RS00545	COG4174	ABC transporter (Permease)
HWQ15_RS00550	COG4239	(ABC) transporter, permease
HWQ15_RS00555	COG4172	Belongs to the ABC transporter superfamily
HWQ15_RS00565	COG2814	Major facilitator Superfamily
HWQ15_RS00570	COG1187	pseudouridine synthase activity
HWQ15_RS00575	COG1061	Type III restriction enzyme res subunit
HWQ15_RS00585	COG3081	Nucleoid-associated protein
HWQ15_RS00590	COG3082	Protein of unknown function (DUF1414)
HWQ15_RS00605	COG3182	Iron-regulated membrane protein
HWQ15_RS00620	COG0659	secondary active sulfate transmembrane transporter activity
HWQ15_RS00625	COG2239	Acts as a magnesium transporter
HWQ15_RS00630	COG4615	Cyclic peptide transporter
HWQ15_RS00640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HWQ15_RS00640	COG2169	Transcriptional regulator
HWQ15_RS00655	COG0642	Histidine kinase
HWQ15_RS00655	COG2198	Histidine kinase
HWQ15_RS00675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HWQ15_RS00690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HWQ15_RS00695	COG0584	glycerophosphoryl diester phosphodiesterase
HWQ15_RS00700	COG2271	Major facilitator Superfamily
HWQ15_RS00705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HWQ15_RS00710	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HWQ15_RS00715	COG0247	lactate metabolic process
HWQ15_RS00730	COG0642	Histidine kinase
HWQ15_RS00760	COG1441	menaquinone biosynthetic process
HWQ15_RS00770	COG0596	Alpha beta hydrolase
HWQ15_RS00775	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HWQ15_RS00780	COG1169	isochorismate synthase
HWQ15_RS00785	COG4575	ribosome binding
HWQ15_RS00790	COG2153	protein acetylation
HWQ15_RS00795	COG1234	tRNA 3'-trailer cleavage
HWQ15_RS00800	COG0835	chemotaxis
HWQ15_RS00800	COG0784	Response regulator, receiver
HWQ15_RS00805	COG1007	ATP synthesis coupled electron transport
HWQ15_RS00810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HWQ15_RS00815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HWQ15_RS00820	COG0713	ATP synthesis coupled electron transport
HWQ15_RS00825	COG0839	Belongs to the complex I subunit 6 family
HWQ15_RS00835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HWQ15_RS00865	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HWQ15_RS00870	COG0583	DNA-binding transcription factor activity
HWQ15_RS00875	COG0436	Aminotransferase
HWQ15_RS00885	COG0471	metal ion transport
HWQ15_RS00885	COG0490	domain, Protein
HWQ15_RS00890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HWQ15_RS00915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HWQ15_RS00920	COG3959	Transketolase, thiamine diphosphate binding domain
HWQ15_RS00925	COG3037	sugar-specific permease SgaT UlaA
HWQ15_RS00935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS00940	COG1609	Transcriptional regulator
HWQ15_RS00950	COG0622	Phosphoesterase
HWQ15_RS00955	COG0625	glutathione transferase activity
HWQ15_RS00960	COG0625	glutathione transferase activity
HWQ15_RS00965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HWQ15_RS00970	COG1090	epimerase
HWQ15_RS00990	COG3423	Transcriptional regulator
HWQ15_RS00995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS01000	COG4598	ABC transporter
HWQ15_RS01005	COG4160	amino acid transport
HWQ15_RS01015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS01025	COG0163	prenyltransferase activity
HWQ15_RS01030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HWQ15_RS01035	COG1286	toxin biosynthetic process
HWQ15_RS01040	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HWQ15_RS01045	COG0285	dihydrofolate synthase activity
HWQ15_RS01050	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HWQ15_RS01055	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS01060	COG0101	tRNA pseudouridine synthase activity
HWQ15_RS01065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HWQ15_RS01070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HWQ15_RS01085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HWQ15_RS01090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HWQ15_RS01090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HWQ15_RS01100	COG3101	peptidyl-lysine hydroxylation
HWQ15_RS01105	COG0730	response to heat
HWQ15_RS01115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HWQ15_RS01125	COG2840	Smr protein MutS2
HWQ15_RS01130	COG2062	phosphohistidine phosphatase, SixA
HWQ15_RS01135	COG1250	3-hydroxyacyl-CoA dehydrogenase
HWQ15_RS01135	COG1024	Enoyl-CoA hydratase
HWQ15_RS01145	COG3691	Protein conserved in bacteria
HWQ15_RS01150	COG2067	long-chain fatty acid transport protein
HWQ15_RS01160	COG2116	formate transmembrane transporter activity
HWQ15_RS01170	COG0582	viral genome integration into host DNA
HWQ15_RS01225	COG1560	Kdo2-lipid A biosynthetic process
HWQ15_RS01235	COG0436	Aminotransferase
HWQ15_RS01240	COG3275	phosphorelay sensor kinase activity
HWQ15_RS01245	COG3279	Response regulator of the LytR AlgR family
HWQ15_RS01250	COG0837	glucose binding
HWQ15_RS01260	COG3961	Belongs to the TPP enzyme family
HWQ15_RS01265	COG0667	Aldo Keto reductase
HWQ15_RS01275	COG1914	H( )-stimulated, divalent metal cation uptake system
HWQ15_RS01280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HWQ15_RS01285	COG2200	EAL domain
HWQ15_RS01285	COG2199	diguanylate cyclase activity
HWQ15_RS01300	COG3415	Transposase
HWQ15_RS01305	COG3415	Transposase
HWQ15_RS01310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HWQ15_RS01340	COG0583	DNA-binding transcription factor activity
HWQ15_RS01345	COG0385	Bile acid
HWQ15_RS01350	COG3530	Putative quorum-sensing-regulated virulence factor
HWQ15_RS01355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HWQ15_RS01360	COG3115	cell septum assembly
HWQ15_RS01375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS01400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HWQ15_RS01405	COG4208	sulfate ABC transporter
HWQ15_RS01410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HWQ15_RS01415	COG4150	thiosulfate binding
HWQ15_RS01420	COG2837	iron assimilation
HWQ15_RS01445	COG0408	coproporphyrinogen oxidase activity
HWQ15_RS01460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HWQ15_RS01465	COG5342	invasion associated locus B
HWQ15_RS01470	COG0494	nUDIX hydrolase
HWQ15_RS01475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HWQ15_RS01475	COG0493	'glutamate synthase
HWQ15_RS01480	COG3850	Histidine kinase
HWQ15_RS01485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS01495	COG1393	Belongs to the ArsC family
HWQ15_RS01500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HWQ15_RS01510	COG0400	carboxylic ester hydrolase activity
HWQ15_RS01520	COG2321	neutral zinc metallopeptidase
HWQ15_RS01525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HWQ15_RS01530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HWQ15_RS01540	COG2716	regulation of RNA biosynthetic process
HWQ15_RS01545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HWQ15_RS01550	COG0628	permease
HWQ15_RS01555	COG4783	chaperone-mediated protein folding
HWQ15_RS01560	COG1393	Belongs to the ArsC family
HWQ15_RS01575	COG1446	asparaginase
HWQ15_RS01580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HWQ15_RS01590	COG2233	PERMEase
HWQ15_RS01595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HWQ15_RS01600	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS01610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HWQ15_RS01625	COG2200	EAL domain
HWQ15_RS01645	COG3713	MltA-interacting MipA family protein
HWQ15_RS01650	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS01670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS01675	COG2207	Transcriptional regulator
HWQ15_RS01675	COG3708	Transcriptional regulator
HWQ15_RS01690	COG3179	chitinase
HWQ15_RS01705	COG2246	polysaccharide biosynthetic process
HWQ15_RS01710	COG0463	Glycosyl transferase, family 2
HWQ15_RS01835	COG5484	DNA packaging
HWQ15_RS01835	COG3728	DNA packaging
HWQ15_RS01925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HWQ15_RS01970	COG0516	GMP reductase activity
HWQ15_RS01970	COG0517	IMP dehydrogenase activity
HWQ15_RS01975	COG1570	exodeoxyribonuclease VII activity
HWQ15_RS01990	COG1645	bacterial-type flagellum-dependent swarming motility
HWQ15_RS01995	COG3104	oligopeptide transport
HWQ15_RS02000	COG1160	GTP binding
HWQ15_RS02010	COG2976	Protein conserved in bacteria
HWQ15_RS02015	COG0124	histidyl-tRNA synthetase
HWQ15_RS02020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HWQ15_RS02030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HWQ15_RS02045	COG3302	dmso reductase anchor subunit
HWQ15_RS02050	COG0437	4 iron, 4 sulfur cluster binding
HWQ15_RS02055	COG0243	molybdopterin cofactor binding
HWQ15_RS02060	COG4953	penicillin-binding protein 1C
HWQ15_RS02065	COG2373	Large extracellular alpha-helical protein
HWQ15_RS02070	COG1263	PTS System
HWQ15_RS02070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS02070	COG2190	(PTS) system
HWQ15_RS02080	COG2897	thiosulfate sulfurtransferase activity
HWQ15_RS02085	COG1737	Transcriptional regulator
HWQ15_RS02095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HWQ15_RS02100	COG2975	iron-sulfur cluster assembly
HWQ15_RS02105	COG0633	Ferredoxin
HWQ15_RS02110	COG0443	Heat shock 70 kDa protein
HWQ15_RS02115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HWQ15_RS02120	COG0316	Belongs to the HesB IscA family
HWQ15_RS02125	COG0822	iron-sulfur transferase activity
HWQ15_RS02130	COG1104	cysteine desulfurase activity
HWQ15_RS02150	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HWQ15_RS02160	COG3711	transcriptional antiterminator
HWQ15_RS02165	COG2814	Major facilitator Superfamily
HWQ15_RS02170	COG2259	Doxx family
HWQ15_RS02180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HWQ15_RS02180	COG1017	nitric oxide dioxygenase activity
HWQ15_RS02185	COG0347	Belongs to the P(II) protein family
HWQ15_RS02190	COG2204	response regulator
HWQ15_RS02195	COG3170	Tfp pilus assembly protein FimV
HWQ15_RS02200	COG2205	protein histidine kinase activity
HWQ15_RS02205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HWQ15_RS02205	COG0047	phosphoribosylformylglycinamidine synthase activity
HWQ15_RS02210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HWQ15_RS02220	COG0560	Phosphoserine phosphatase
HWQ15_RS02225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS02225	COG1263	PTS System
HWQ15_RS02230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HWQ15_RS02235	COG1737	Transcriptional regulator
HWQ15_RS02240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HWQ15_RS02250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HWQ15_RS02255	COG1381	Involved in DNA repair and RecF pathway recombination
HWQ15_RS02270	COG0681	Belongs to the peptidase S26 family
HWQ15_RS02280	COG3086	response to oxidative stress
HWQ15_RS02300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HWQ15_RS02305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HWQ15_RS02310	COG0513	Belongs to the DEAD box helicase family
HWQ15_RS02315	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
HWQ15_RS02320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HWQ15_RS02325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HWQ15_RS02330	COG3118	belongs to the thioredoxin family
HWQ15_RS02340	COG1042	CoA-binding domain protein
HWQ15_RS02340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS02340	COG0045	succinate-CoA ligase (ADP-forming) activity
HWQ15_RS02345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HWQ15_RS02350	COG5544	Lipoprotein
HWQ15_RS02355	COG0477	Major facilitator Superfamily
HWQ15_RS02385	COG0542	response to heat
HWQ15_RS02395	COG0564	pseudouridine synthase activity
HWQ15_RS02400	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HWQ15_RS02405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HWQ15_RS02415	COG1605	Chorismate mutase
HWQ15_RS02415	COG0077	Prephenate dehydratase
HWQ15_RS02425	COG1605	Chorismate mutase
HWQ15_RS02425	COG0287	Prephenate dehydrogenase
HWQ15_RS02430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HWQ15_RS02440	COG2199	diguanylate cyclase activity
HWQ15_RS02445	COG2885	chlorophyll binding
HWQ15_RS02465	COG0336	Belongs to the RNA methyltransferase TrmD family
HWQ15_RS02470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HWQ15_RS02480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HWQ15_RS02485	COG4137	Cytochrome C assembly protein
HWQ15_RS02490	COG4536	flavin adenine dinucleotide binding
HWQ15_RS02495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HWQ15_RS02500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HWQ15_RS02505	COG0497	DNA recombination
HWQ15_RS02520	COG2867	negative regulation of translational initiation
HWQ15_RS02535	COG0582	viral genome integration into host DNA
HWQ15_RS02545	COG1204	response to ionizing radiation
HWQ15_RS02600	COG0154	amidase activity
HWQ15_RS02605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HWQ15_RS02625	COG2814	Major facilitator Superfamily
HWQ15_RS02630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HWQ15_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS02655	COG0583	DNA-binding transcription factor activity
HWQ15_RS02665	COG4977	sequence-specific DNA binding
HWQ15_RS02665	COG1917	Cupin 2, conserved barrel domain protein
HWQ15_RS02670	COG4221	oxidoreductase activity
HWQ15_RS02675	COG4221	oxidoreductase activity
HWQ15_RS02700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS02705	COG1051	belongs to the nudix hydrolase family
HWQ15_RS02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HWQ15_RS02735	COG2226	methyltransferase
HWQ15_RS02740	COG3958	Transketolase
HWQ15_RS02745	COG3959	Transketolase, thiamine diphosphate binding domain
HWQ15_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS02755	COG2271	Major facilitator Superfamily
HWQ15_RS02760	COG0583	DNA-binding transcription factor activity
HWQ15_RS02765	COG0402	S-adenosylhomocysteine deaminase activity
HWQ15_RS02770	COG0549	Belongs to the carbamate kinase family
HWQ15_RS02780	COG1304	FMN binding
HWQ15_RS02785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HWQ15_RS02790	COG0666	response to abiotic stimulus
HWQ15_RS02795	COG0583	DNA-binding transcription factor activity
HWQ15_RS02800	COG0401	homolog of Blt101
HWQ15_RS02805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HWQ15_RS02830	COG4575	ribosome binding
HWQ15_RS02840	COG1780	Probably involved in ribonucleotide reductase function
HWQ15_RS02845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HWQ15_RS02855	COG4175	Glycine betaine
HWQ15_RS02860	COG4176	ABC-type proline glycine betaine transport system permease component
HWQ15_RS02870	COG2814	Major facilitator Superfamily
HWQ15_RS02875	COG1846	Transcriptional regulator
HWQ15_RS02880	COG1566	PFAM secretion protein HlyD family protein
HWQ15_RS02885	COG2814	Major facilitator Superfamily
HWQ15_RS02895	COG2918	glutathione biosynthetic process
HWQ15_RS02900	COG1238	metal cluster binding
HWQ15_RS02905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HWQ15_RS02935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HWQ15_RS02940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HWQ15_RS02955	COG1546	Belongs to the CinA family
HWQ15_RS02965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HWQ15_RS02975	COG2951	lytic endotransglycosylase activity
HWQ15_RS02980	COG3730	PTS system glucitol sorbitol-specific
HWQ15_RS02985	COG3732	PTS system glucitol sorbitol-specific
HWQ15_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS03000	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS03005	COG1349	DNA-binding transcription factor activity
HWQ15_RS03015	COG3604	Transcriptional regulator
HWQ15_RS03020	COG1773	rubredoxin
HWQ15_RS03020	COG0426	domain, Protein
HWQ15_RS03025	COG0446	pyridine nucleotide-disulphide oxidoreductase
HWQ15_RS03030	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HWQ15_RS03035	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HWQ15_RS03040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HWQ15_RS03045	COG1609	Transcriptional regulator
HWQ15_RS03050	COG1263	PTS System
HWQ15_RS03050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS03055	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS03060	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HWQ15_RS03070	COG3260	NADH ubiquinone oxidoreductase 20
HWQ15_RS03075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HWQ15_RS03080	COG3261	NADH dehydrogenase
HWQ15_RS03080	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HWQ15_RS03085	COG0650	Formate hydrogenlyase subunit 4
HWQ15_RS03090	COG0651	ATP synthesis coupled electron transport
HWQ15_RS03095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HWQ15_RS03105	COG0375	protein maturation
HWQ15_RS03110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HWQ15_RS03115	COG0298	carbon dioxide binding
HWQ15_RS03120	COG0409	Hydrogenase expression formation protein
HWQ15_RS03125	COG0309	Hydrogenase expression formation protein (HypE)
HWQ15_RS03145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HWQ15_RS03155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HWQ15_RS03160	COG0163	prenyltransferase activity
HWQ15_RS03175	COG0477	Major facilitator Superfamily
HWQ15_RS03190	COG1388	LysM domain
HWQ15_RS03190	COG4942	peptidase
HWQ15_RS03205	COG0585	pseudouridine synthase activity
HWQ15_RS03210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HWQ15_RS03215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HWQ15_RS03220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HWQ15_RS03230	COG0529	Catalyzes the synthesis of activated sulfate
HWQ15_RS03250	COG2234	aminopeptidase activity
HWQ15_RS03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HWQ15_RS03270	COG0720	synthase
HWQ15_RS03275	COG2207	Transcriptional regulator
HWQ15_RS03280	COG1473	amidohydrolase
HWQ15_RS03290	COG0602	queuosine metabolic process
HWQ15_RS03295	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HWQ15_RS03300	COG1263	PTS System
HWQ15_RS03300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS03300	COG2190	(PTS) system
HWQ15_RS03305	COG1737	Transcriptional regulator
HWQ15_RS03320	COG3956	TIGRFAM MazG family protein
HWQ15_RS03325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HWQ15_RS03330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HWQ15_RS03335	COG2205	protein histidine kinase activity
HWQ15_RS03335	COG3437	response regulator, receiver
HWQ15_RS03335	COG3850	Histidine kinase
HWQ15_RS03335	COG4999	Histidine kinase
HWQ15_RS03340	COG1929	Belongs to the glycerate kinase type-1 family
HWQ15_RS03350	COG4948	Mandelate Racemase Muconate Lactonizing
HWQ15_RS03355	COG2271	Major facilitator Superfamily
HWQ15_RS03360	COG0716	FMN binding
HWQ15_RS03365	COG0564	pseudouridine synthase activity
HWQ15_RS03370	COG3098	single-species biofilm formation
HWQ15_RS03385	COG1611	Belongs to the LOG family
HWQ15_RS03390	COG0814	amino acid
HWQ15_RS03395	COG1760	l-serine dehydratase
HWQ15_RS03405	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HWQ15_RS03410	COG2363	Small membrane protein
HWQ15_RS03415	COG0583	DNA-binding transcription factor activity
HWQ15_RS03425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HWQ15_RS03430	COG2166	iron-sulfur cluster assembly
HWQ15_RS03435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HWQ15_RS03440	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HWQ15_RS03460	COG0860	N-Acetylmuramoyl-L-alanine amidase
HWQ15_RS03465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HWQ15_RS03465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HWQ15_RS03470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HWQ15_RS03475	COG1074	ATP-dependent DNA helicase activity
HWQ15_RS03485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HWQ15_RS03490	COG4967	type IV pilus modification protein PilV
HWQ15_RS03500	COG4795	General secretion pathway protein
HWQ15_RS03505	COG2165	general secretion pathway protein
HWQ15_RS03510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HWQ15_RS03515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HWQ15_RS03525	COG0494	nUDIX hydrolase
HWQ15_RS03530	COG3066	DNA modification
HWQ15_RS03540	COG0667	Aldo Keto reductase
HWQ15_RS03545	COG0477	Major facilitator Superfamily
HWQ15_RS03550	COG0318	PFAM AMP-dependent synthetase and ligase
HWQ15_RS03550	COG0204	Acyl-transferase
HWQ15_RS03555	COG1609	Transcriptional regulator
HWQ15_RS03565	COG2186	Transcriptional regulator
HWQ15_RS03570	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS03575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS03580	COG1609	Transcriptional regulator
HWQ15_RS03590	COG0583	DNA-binding transcription factor activity
HWQ15_RS03595	COG1794	racemase activity, acting on amino acids and derivatives
HWQ15_RS03605	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HWQ15_RS03610	COG1175	transmembrane transport
HWQ15_RS03615	COG0395	ABC-type sugar transport system, permease component
HWQ15_RS03620	COG3842	ATPase activity
HWQ15_RS03630	COG2814	Major facilitator Superfamily
HWQ15_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS03640	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HWQ15_RS03645	COG0823	Involved in the tonB-independent uptake of proteins
HWQ15_RS03650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HWQ15_RS03655	COG0183	Belongs to the thiolase family
HWQ15_RS03670	COG0814	amino acid
HWQ15_RS03675	COG2388	GCN5-related N-acetyl-transferase
HWQ15_RS03680	COG3592	Divergent 4Fe-4S mono-cluster
HWQ15_RS03685	COG3729	General stress protein
HWQ15_RS03690	COG3685	Protein conserved in bacteria
HWQ15_RS03695	COG3685	Protein conserved in bacteria
HWQ15_RS03700	COG3546	catalase activity
HWQ15_RS03705	COG1271	oxidase subunit
HWQ15_RS03710	COG1294	oxidase, subunit
HWQ15_RS03725	COG1546	Belongs to the CinA family
HWQ15_RS03740	COG3111	PFAM Bacterial OB fold (BOF) protein
HWQ15_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS03750	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HWQ15_RS03770	COG2067	long-chain fatty acid transport protein
HWQ15_RS03790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HWQ15_RS03810	COG4942	peptidase
HWQ15_RS03815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HWQ15_RS03820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HWQ15_RS03830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HWQ15_RS03840	COG4974	Belongs to the 'phage' integrase family
HWQ15_RS03855	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HWQ15_RS03860	COG0354	folic acid binding
HWQ15_RS03865	COG1272	protein, Hemolysin III
HWQ15_RS03870	COG1737	Transcriptional regulator
HWQ15_RS03875	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS03895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HWQ15_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS03905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HWQ15_RS03905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HWQ15_RS03915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HWQ15_RS03920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HWQ15_RS03925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HWQ15_RS03930	COG0006	proline dipeptidase activity
HWQ15_RS03940	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HWQ15_RS03950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HWQ15_RS03960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HWQ15_RS03970	COG0583	DNA-binding transcription factor activity
HWQ15_RS03975	COG2968	Membrane
HWQ15_RS03980	COG1279	arginine transmembrane transporter activity
HWQ15_RS03985	COG0668	transmembrane transport
HWQ15_RS03990	COG0191	fructose-bisphosphate aldolase activity
HWQ15_RS03995	COG0126	phosphoglycerate kinase activity
HWQ15_RS04000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HWQ15_RS04005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HWQ15_RS04010	COG0501	Belongs to the peptidase M48B family
HWQ15_RS04025	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HWQ15_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS04035	COG2267	carboxylic ester hydrolase activity
HWQ15_RS04060	COG1414	Transcriptional regulator
HWQ15_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS04080	COG2146	nitrite reductase [NAD(P)H] activity
HWQ15_RS04090	COG0010	Belongs to the arginase family
HWQ15_RS04095	COG1166	arginine decarboxylase activity
HWQ15_RS04115	COG2814	Major facilitator Superfamily
HWQ15_RS04120	COG3091	SprT-like family
HWQ15_RS04125	COG2356	endonuclease I
HWQ15_RS04130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HWQ15_RS04150	COG2805	Type II/IV secretion system protein
HWQ15_RS04155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HWQ15_RS04160	COG0762	integral membrane protein
HWQ15_RS04165	COG1872	DUF167
HWQ15_RS04175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HWQ15_RS04180	COG2852	Protein conserved in bacteria
HWQ15_RS04190	COG3171	Protein conserved in bacteria
HWQ15_RS04200	COG1194	a g-specific adenine glycosylase
HWQ15_RS04210	COG0741	lytic transglycosylase activity
HWQ15_RS04215	COG2211	Major facilitator Superfamily
HWQ15_RS04220	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HWQ15_RS04240	COG3052	prosthetic group binding
HWQ15_RS04250	COG0179	Fumarylacetoacetate (FAA) hydrolase
HWQ15_RS04255	COG3493	citrate carrier protein
HWQ15_RS04270	COG1982	Orn Lys Arg decarboxylase major
HWQ15_RS04275	COG1811	Na channel or pump
HWQ15_RS04295	COG5002	protein histidine kinase activity
HWQ15_RS04300	COG2197	response regulator
HWQ15_RS04320	COG0457	Tetratricopeptide repeat
HWQ15_RS04325	COG1649	PFAM Uncharacterised BCR, COG1649
HWQ15_RS04325	COG0726	polysaccharide deacetylase
HWQ15_RS04330	COG1215	transferase activity, transferring glycosyl groups
HWQ15_RS04340	COG0754	glutathionylspermidine amidase activity
HWQ15_RS04345	COG0625	glutathione transferase activity
HWQ15_RS04350	COG1349	DNA-binding transcription factor activity
HWQ15_RS04355	COG0840	transmembrane signaling receptor activity
HWQ15_RS04365	COG0667	Aldo Keto reductase
HWQ15_RS04370	COG2862	Uncharacterized protein family, UPF0114
HWQ15_RS04390	COG0848	biopolymer transport protein
HWQ15_RS04400	COG0626	cystathionine gamma-synthase activity
HWQ15_RS04405	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS04410	COG2207	Transcriptional regulator
HWQ15_RS04415	COG1979	alcohol dehydrogenase
HWQ15_RS04425	COG1032	radical SAM domain protein
HWQ15_RS04435	COG0204	Acyl-transferase
HWQ15_RS04445	COG3111	PFAM Bacterial OB fold (BOF) protein
HWQ15_RS04460	COG2249	NAD(P)H dehydrogenase (quinone) activity
HWQ15_RS04465	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HWQ15_RS04470	COG1652	LysM domain
HWQ15_RS04485	COG2211	Major facilitator Superfamily
HWQ15_RS04510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS04515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS04520	COG1120	ATPase activity
HWQ15_RS04525	COG4774	siderophore transport
HWQ15_RS04530	COG0187	DNA topoisomerase II activity
HWQ15_RS04535	COG3150	esterase
HWQ15_RS04540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HWQ15_RS04545	COG3151	Protein conserved in bacteria
HWQ15_RS04550	COG0494	nUDIX hydrolase
HWQ15_RS04565	COG0754	glutathionylspermidine amidase activity
HWQ15_RS04570	COG3384	dioxygenase
HWQ15_RS04580	COG3539	Fimbrial protein
HWQ15_RS04585	COG3188	usher protein
HWQ15_RS04590	COG3121	Chaperone
HWQ15_RS04595	COG3539	Fimbrial protein
HWQ15_RS04600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HWQ15_RS04610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HWQ15_RS04610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HWQ15_RS04620	COG3025	triphosphatase activity
HWQ15_RS04625	COG4991	sh3 domain protein
HWQ15_RS04630	COG0617	tRNA 3'-terminal CCA addition
HWQ15_RS04640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HWQ15_RS04650	COG2271	Major facilitator Superfamily
HWQ15_RS04655	COG0829	nickel cation binding
HWQ15_RS04660	COG0831	urea catabolic process
HWQ15_RS04665	COG0832	Belongs to the urease beta subunit family
HWQ15_RS04670	COG0804	urea catabolic process
HWQ15_RS04675	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HWQ15_RS04685	COG0830	nickel cation binding
HWQ15_RS04690	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HWQ15_RS04700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HWQ15_RS04705	COG0358	DNA primase activity
HWQ15_RS04715	COG3663	DNA glycosylase
HWQ15_RS04750	COG2375	cellular response to nickel ion
HWQ15_RS04755	COG1695	Transcriptional regulator
HWQ15_RS04760	COG0840	transmembrane signaling receptor activity
HWQ15_RS04765	COG0840	transmembrane signaling receptor activity
HWQ15_RS04770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HWQ15_RS04775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HWQ15_RS04780	COG1830	Aldolase
HWQ15_RS04785	COG1879	ABC-type sugar transport system periplasmic component
HWQ15_RS04790	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS04795	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS04800	COG1129	ABC transporter
HWQ15_RS04805	COG2390	Transcriptional regulator
HWQ15_RS04810	COG1070	Carbohydrate kinase
HWQ15_RS04815	COG1902	pentaerythritol trinitrate reductase activity
HWQ15_RS04815	COG0446	pyridine nucleotide-disulphide oxidoreductase
HWQ15_RS04825	COG1451	nucleotide metabolic process
HWQ15_RS04830	COG0673	inositol 2-dehydrogenase activity
HWQ15_RS04835	COG0861	Integral membrane protein TerC family
HWQ15_RS04845	COG2721	sulfolactate sulfo-lyase activity
HWQ15_RS04855	COG2271	Major facilitator Superfamily
HWQ15_RS04860	COG2186	Transcriptional regulator
HWQ15_RS04865	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS04875	COG1422	Protein of unknown function (DUF1090)
HWQ15_RS04880	COG4575	ribosome binding
HWQ15_RS04885	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HWQ15_RS04895	COG2259	Doxx family
HWQ15_RS04900	COG0435	Glutathione S-transferase
HWQ15_RS04905	COG3152	Membrane
HWQ15_RS04910	COG0583	DNA-binding transcription factor activity
HWQ15_RS04915	COG1741	Belongs to the pirin family
HWQ15_RS04925	COG0814	amino acid
HWQ15_RS04930	COG1882	Formate acetyltransferase
HWQ15_RS04935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HWQ15_RS04940	COG0814	amino acid
HWQ15_RS04945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HWQ15_RS04950	COG0583	DNA-binding transcription factor activity
HWQ15_RS05025	COG1929	Belongs to the glycerate kinase type-1 family
HWQ15_RS05030	COG2084	Dehydrogenase
HWQ15_RS05040	COG2721	sulfolactate sulfo-lyase activity
HWQ15_RS05045	COG1349	DNA-binding transcription factor activity
HWQ15_RS05055	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS05065	COG3716	PTS system mannose fructose sorbose family IID component
HWQ15_RS05070	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS05075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HWQ15_RS05080	COG2222	sugar isomerase
HWQ15_RS05085	COG0191	fructose-bisphosphate aldolase activity
HWQ15_RS05090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS05090	COG1263	PTS System
HWQ15_RS05105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HWQ15_RS05110	COG3107	peptidoglycan biosynthetic process
HWQ15_RS05115	COG0792	nuclease activity
HWQ15_RS05120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HWQ15_RS05125	COG2823	Periplasmic or secreted lipoprotein
HWQ15_RS05130	COG0701	Predicted permease
HWQ15_RS05135	COG0702	epimerase
HWQ15_RS05140	COG0693	protein deglycase activity
HWQ15_RS05145	COG3787	Belongs to the UPF0306 family
HWQ15_RS05150	COG2827	Endonuclease containing a URI domain
HWQ15_RS05155	COG3153	acetyltransferase
HWQ15_RS05160	COG3154	lipid carrier protein
HWQ15_RS05165	COG0826	peptidase U32
HWQ15_RS05170	COG0826	peptidase U32
HWQ15_RS05175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS05180	COG0814	amino acid
HWQ15_RS05185	COG0513	Belongs to the DEAD box helicase family
HWQ15_RS05200	COG1185	polyribonucleotide nucleotidyltransferase activity
HWQ15_RS05205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HWQ15_RS05210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HWQ15_RS05215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HWQ15_RS05220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HWQ15_RS05240	COG0137	argininosuccinate synthase activity
HWQ15_RS05250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HWQ15_RS05255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HWQ15_RS05260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HWQ15_RS05270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HWQ15_RS05275	COG1534	Rna-binding protein
HWQ15_RS05285	COG2027	D-alanyl-D-alanine carboxypeptidase
HWQ15_RS05290	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS05295	COG0642	Histidine kinase
HWQ15_RS05300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HWQ15_RS05305	COG0697	spore germination
HWQ15_RS05315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HWQ15_RS05320	COG0142	geranyltranstransferase activity
HWQ15_RS05325	COG3423	Transcriptional regulator
HWQ15_RS05330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HWQ15_RS05335	COG5007	Belongs to the BolA IbaG family
HWQ15_RS05340	COG3113	response to antibiotic
HWQ15_RS05345	COG2854	intermembrane phospholipid transfer
HWQ15_RS05350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HWQ15_RS05355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HWQ15_RS05360	COG1127	ABC transporter
HWQ15_RS05365	COG0530	calcium, potassium:sodium antiporter activity
HWQ15_RS05375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HWQ15_RS05380	COG3117	lipopolysaccharide transmembrane transporter activity
HWQ15_RS05385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HWQ15_RS05390	COG1137	ATPase activity
HWQ15_RS05395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HWQ15_RS05415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS05425	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HWQ15_RS05430	COG0784	Response regulator, receiver
HWQ15_RS05430	COG5002	protein histidine kinase activity
HWQ15_RS05430	COG2198	Histidine kinase
HWQ15_RS05435	COG0795	lipopolysaccharide-transporting ATPase activity
HWQ15_RS05440	COG0795	lipopolysaccharide-transporting ATPase activity
HWQ15_RS05445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HWQ15_RS05450	COG2927	DNA polymerase III (CHI subunit)
HWQ15_RS05460	COG0456	acetyltransferase
HWQ15_RS05465	COG1064	alcohol dehydrogenase
HWQ15_RS05475	COG0433	COG0433 Predicted ATPase
HWQ15_RS05480	COG1242	4 iron, 4 sulfur cluster binding
HWQ15_RS05485	COG0069	glutamate synthase activity
HWQ15_RS05485	COG0067	glutamate synthase
HWQ15_RS05485	COG0070	glutamate synthase
HWQ15_RS05490	COG0493	'glutamate synthase
HWQ15_RS05495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HWQ15_RS05500	COG0402	S-adenosylhomocysteine deaminase activity
HWQ15_RS05505	COG3539	Fimbrial protein
HWQ15_RS05515	COG3188	usher protein
HWQ15_RS05520	COG3121	Chaperone
HWQ15_RS05525	COG3539	Fimbrial protein
HWQ15_RS05530	COG3539	Fimbrial protein
HWQ15_RS05535	COG2969	positive regulation of protein catabolic process
HWQ15_RS05540	COG0625	glutathione transferase activity
HWQ15_RS05545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HWQ15_RS05555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HWQ15_RS05560	COG3105	Protein conserved in bacteria
HWQ15_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HWQ15_RS05570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HWQ15_RS05580	COG1438	arginine binding
HWQ15_RS05590	COG2732	(Barnase) inhibitor
HWQ15_RS05595	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS05600	COG1289	transmembrane transporter activity
HWQ15_RS05615	COG0583	DNA-binding transcription factor activity
HWQ15_RS05620	COG0312	modulator of DNA gyrase
HWQ15_RS05625	COG3164	Protein of unknown function
HWQ15_RS05630	COG1530	ribonuclease E activity
HWQ15_RS05640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HWQ15_RS05645	COG1792	Involved in formation and maintenance of cell shape
HWQ15_RS05650	COG1077	Cell shape determining protein MreB Mrl
HWQ15_RS05655	COG2200	EAL domain
HWQ15_RS05655	COG2199	diguanylate cyclase activity
HWQ15_RS05660	COG0604	alcohol dehydrogenase
HWQ15_RS05670	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HWQ15_RS05675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HWQ15_RS05680	COG0511	ligase activity, forming carbon-carbon bonds
HWQ15_RS05685	COG0439	Biotin carboxylase
HWQ15_RS05690	COG3924	membrane
HWQ15_RS05695	COG4145	pantothenate transmembrane transporter activity
HWQ15_RS05730	COG1309	transcriptional regulator
HWQ15_RS05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS05740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS05780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HWQ15_RS05790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HWQ15_RS05795	COG0009	L-threonylcarbamoyladenylate synthase
HWQ15_RS05800	COG0551	DNA topoisomerase type I activity
HWQ15_RS05805	COG2922	Belongs to the Smg family
HWQ15_RS05810	COG0758	DNA mediated transformation
HWQ15_RS05815	COG0242	peptide deformylase activity
HWQ15_RS05820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HWQ15_RS05825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HWQ15_RS05825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HWQ15_RS05835	COG1970	mechanosensitive ion channel activity
HWQ15_RS05840	COG3036	rescue of stalled ribosome
HWQ15_RS05845	COG0789	Transcriptional regulator
HWQ15_RS05860	COG0202	RNA polymerase activity
HWQ15_RS05870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HWQ15_RS05885	COG0201	protein transport
HWQ15_RS05895	COG1841	ribosomal large subunit assembly
HWQ15_RS05910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HWQ15_RS05915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HWQ15_RS05945	COG0255	Belongs to the universal ribosomal protein uL29 family
HWQ15_RS05950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HWQ15_RS05990	COG0051	transcription antitermination factor activity, RNA binding
HWQ15_RS06030	COG2168	tRNA wobble position uridine thiolation
HWQ15_RS06035	COG2923	Belongs to the DsrF TusC family
HWQ15_RS06040	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HWQ15_RS06045	COG2964	Protein conserved in bacteria
HWQ15_RS06050	COG0545	Peptidyl-prolyl cis-trans isomerase
HWQ15_RS06055	COG2900	Belongs to the SlyX family
HWQ15_RS06060	COG1047	Peptidyl-prolyl cis-trans
HWQ15_RS06065	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HWQ15_RS06070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HWQ15_RS06070	COG0475	glutathione-regulated potassium exporter activity
HWQ15_RS06075	COG2249	NAD(P)H dehydrogenase (quinone) activity
HWQ15_RS06080	COG0488	(ABC) transporter
HWQ15_RS06090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HWQ15_RS06100	COG0679	Auxin Efflux Carrier
HWQ15_RS06130	COG0429	hydrolase of the alpha beta-hydrolase fold
HWQ15_RS06135	COG3089	Belongs to the UPF0270 family
HWQ15_RS06140	COG3954	Phosphoribulokinase
HWQ15_RS06145	COG1765	OsmC-like protein
HWQ15_RS06155	COG1289	transmembrane transporter activity
HWQ15_RS06160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HWQ15_RS06165	COG0512	Glutamine amidotransferase of anthranilate synthase
HWQ15_RS06170	COG2184	nucleotidyltransferase activity
HWQ15_RS06180	COG0738	Major facilitator superfamily
HWQ15_RS06185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HWQ15_RS06195	COG1648	precorrin-2 dehydrogenase activity
HWQ15_RS06195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HWQ15_RS06205	COG0180	Tryptophanyl-tRNA synthetase
HWQ15_RS06215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HWQ15_RS06220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HWQ15_RS06225	COG3266	domain, Protein
HWQ15_RS06230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HWQ15_RS06235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HWQ15_RS06240	COG4796	Type ii and iii secretion system protein
HWQ15_RS06260	COG4972	Pilus assembly protein
HWQ15_RS06265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HWQ15_RS06270	COG0494	nUDIX hydrolase
HWQ15_RS06280	COG1011	Hydrolase
HWQ15_RS06285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HWQ15_RS06290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HWQ15_RS06295	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HWQ15_RS06300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HWQ15_RS06310	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS06315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HWQ15_RS06320	COG2183	response to ionizing radiation
HWQ15_RS06325	COG1918	ferrous iron import across plasma membrane
HWQ15_RS06345	COG1040	competence protein
HWQ15_RS06355	COG2610	gluconate transmembrane transporter activity
HWQ15_RS06360	COG1640	4-alpha-glucanotransferase
HWQ15_RS06365	COG0058	SHG alpha-glucan phosphorylase activity
HWQ15_RS06370	COG2909	trisaccharide binding
HWQ15_RS06375	COG1349	DNA-binding transcription factor activity
HWQ15_RS06380	COG0705	Rhomboid family
HWQ15_RS06385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HWQ15_RS06390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HWQ15_RS06395	COG0058	SHG alpha-glucan phosphorylase activity
HWQ15_RS06400	COG0297	glycogen (starch) synthase activity
HWQ15_RS06405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HWQ15_RS06410	COG1523	belongs to the glycosyl hydrolase 13 family
HWQ15_RS06415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HWQ15_RS06420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HWQ15_RS06425	COG2095	MarC family integral membrane protein
HWQ15_RS06445	COG2610	gluconate transmembrane transporter activity
HWQ15_RS06450	COG3265	gluconokinase activity
HWQ15_RS06455	COG1609	Transcriptional regulator
HWQ15_RS06460	COG1741	Belongs to the pirin family
HWQ15_RS06465	COG0673	inositol 2-dehydrogenase activity
HWQ15_RS06470	COG1247	-acetyltransferase
HWQ15_RS06475	COG0405	Gamma-glutamyltransferase
HWQ15_RS06485	COG0584	glycerophosphoryl diester phosphodiesterase
HWQ15_RS06515	COG0411	ABC transporter
HWQ15_RS06530	COG0683	leucine binding
HWQ15_RS06540	COG0683	leucine binding
HWQ15_RS06545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HWQ15_RS06550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HWQ15_RS06555	COG2177	Part of the ABC transporter FtsEX involved in
HWQ15_RS06560	COG2884	Cell division ATP-binding protein ftsE
HWQ15_RS06565	COG0552	protein localization to endoplasmic reticulum
HWQ15_RS06570	COG0742	ribosomal rna small subunit methyltransferase
HWQ15_RS06575	COG3776	membrane
HWQ15_RS06585	COG3714	YhhN family
HWQ15_RS06590	COG2217	Heavy metal translocating P-type atpase
HWQ15_RS06605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HWQ15_RS06610	COG0425	Belongs to the sulfur carrier protein TusA family
HWQ15_RS06615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HWQ15_RS06625	COG0628	permease
HWQ15_RS06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HWQ15_RS06665	COG1216	Glycosyl transferase, family 2
HWQ15_RS06690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HWQ15_RS06700	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS06705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HWQ15_RS06715	COG3479	Phenolic acid decarboxylase
HWQ15_RS06720	COG0583	DNA-binding transcription factor activity
HWQ15_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS06745	COG1414	Transcriptional regulator
HWQ15_RS06750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HWQ15_RS06755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HWQ15_RS06765	COG2205	protein histidine kinase activity
HWQ15_RS06770	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS06775	COG1276	copper resistance
HWQ15_RS06780	COG2372	response to copper ion
HWQ15_RS06785	COG3667	copper resistance
HWQ15_RS06795	COG3039	Transposase
HWQ15_RS06810	COG0739	heme binding
HWQ15_RS06840	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS06905	COG2081	HI0933 family
HWQ15_RS06910	COG0306	phosphate transporter
HWQ15_RS06920	COG0589	response to stress
HWQ15_RS06925	COG0742	ribosomal rna small subunit methyltransferase
HWQ15_RS06930	COG0339	signal peptide processing
HWQ15_RS06935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HWQ15_RS06940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HWQ15_RS06955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS06965	COG2197	response regulator
HWQ15_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS06975	COG0583	DNA-binding transcription factor activity
HWQ15_RS06980	COG1295	ribonuclease BN
HWQ15_RS06985	COG0477	Major facilitator Superfamily
HWQ15_RS06990	COG2982	Protein involved in outer membrane biogenesis
HWQ15_RS06995	COG2200	EAL domain
HWQ15_RS07005	COG0612	Peptidase, M16
HWQ15_RS07010	COG1301	dicarboxylic acid transport
HWQ15_RS07015	COG2200	EAL domain
HWQ15_RS07015	COG2199	diguanylate cyclase activity
HWQ15_RS07020	COG3118	belongs to the thioredoxin family
HWQ15_RS07020	COG0457	Tetratricopeptide repeat
HWQ15_RS07025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HWQ15_RS07035	COG1215	transferase activity, transferring glycosyl groups
HWQ15_RS07060	COG2194	sulfuric ester hydrolase activity
HWQ15_RS07070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HWQ15_RS07100	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HWQ15_RS07110	COG1739	Uncharacterized protein family UPF0029
HWQ15_RS07115	COG0006	proline dipeptidase activity
HWQ15_RS07120	COG1250	3-hydroxyacyl-CoA dehydrogenase
HWQ15_RS07120	COG1024	Enoyl-CoA hydratase
HWQ15_RS07125	COG0183	Belongs to the thiolase family
HWQ15_RS07130	COG0751	glycine-tRNA ligase activity
HWQ15_RS07135	COG0752	glycyl-tRNA synthetase alpha subunit
HWQ15_RS07145	COG3274	enterobacterial common antigen metabolic process
HWQ15_RS07150	COG1070	Carbohydrate kinase
HWQ15_RS07155	COG2115	Belongs to the xylose isomerase family
HWQ15_RS07160	COG4213	ABC transporter substrate-binding protein
HWQ15_RS07170	COG4214	carbohydrate transport
HWQ15_RS07175	COG2207	Transcriptional regulator
HWQ15_RS07175	COG1609	Transcriptional regulator
HWQ15_RS07180	COG2992	FlgJ-related protein
HWQ15_RS07185	COG0366	Alpha amylase catalytic
HWQ15_RS07190	COG3977	Valine--pyruvate aminotransferase
HWQ15_RS07195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HWQ15_RS07200	COG1414	Transcriptional regulator
HWQ15_RS07210	COG2731	YhcH YjgK YiaL family protein
HWQ15_RS07220	COG2271	Major facilitator Superfamily
HWQ15_RS07225	COG1070	Carbohydrate kinase
HWQ15_RS07230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HWQ15_RS07235	COG3623	hexulose-6-phosphate isomerase
HWQ15_RS07240	COG0235	Class ii aldolase
HWQ15_RS07250	COG2211	Major facilitator Superfamily
HWQ15_RS07260	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS07265	COG1940	carbohydrate kinase activity
HWQ15_RS07270	COG3276	selenocysteine insertion sequence binding
HWQ15_RS07280	COG0625	glutathione transferase activity
HWQ15_RS07285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS07285	COG2213	PTS system mannitol-specific
HWQ15_RS07295	COG3722	fumarate hydratase activity
HWQ15_RS07310	COG3188	usher protein
HWQ15_RS07315	COG3121	Chaperone
HWQ15_RS07320	COG3539	Fimbrial protein
HWQ15_RS07330	COG2186	Transcriptional regulator
HWQ15_RS07335	COG1304	FMN binding
HWQ15_RS07340	COG2271	Major facilitator Superfamily
HWQ15_RS07345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HWQ15_RS07355	COG0583	DNA-binding transcription factor activity
HWQ15_RS07360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HWQ15_RS07370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HWQ15_RS07375	COG3978	acetolactate synthase activity
HWQ15_RS07395	COG3085	chromosome segregation
HWQ15_RS07445	COG4206	TonB-dependent receptor
HWQ15_RS07450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HWQ15_RS07470	COG0583	DNA-binding transcription factor activity
HWQ15_RS07475	COG0165	Argininosuccinate lyase
HWQ15_RS07485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HWQ15_RS07490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HWQ15_RS07495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HWQ15_RS07500	COG2207	Transcriptional regulator
HWQ15_RS07510	COG0371	Dehydrogenase
HWQ15_RS07515	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HWQ15_RS07520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HWQ15_RS07525	COG0460	homoserine dehydrogenase
HWQ15_RS07525	COG0527	aspartate kinase activity
HWQ15_RS07530	COG0626	cystathionine gamma-synthase activity
HWQ15_RS07540	COG0254	rRNA binding
HWQ15_RS07545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HWQ15_RS07550	COG1609	Transcriptional regulator
HWQ15_RS07555	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HWQ15_RS07570	COG1575	Belongs to the MenA family. Type 1 subfamily
HWQ15_RS07580	COG3074	FtsZ-dependent cytokinesis
HWQ15_RS07585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HWQ15_RS07590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HWQ15_RS07595	COG1494	fructose-1,6-bisphosphatase
HWQ15_RS07605	COG3152	Membrane
HWQ15_RS07615	COG0149	triose-phosphate isomerase activity
HWQ15_RS07625	COG2134	cdp-diacylglycerol pyrophosphatase
HWQ15_RS07635	COG0205	6-phosphofructokinase activity
HWQ15_RS07645	COG3678	ATP-independent chaperone mediated protein folding
HWQ15_RS07650	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS07655	COG2205	protein histidine kinase activity
HWQ15_RS07660	COG2258	MOSC domain
HWQ15_RS07665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HWQ15_RS07675	COG4977	sequence-specific DNA binding
HWQ15_RS07675	COG1917	Cupin 2, conserved barrel domain protein
HWQ15_RS07680	COG4977	sequence-specific DNA binding
HWQ15_RS07685	COG1070	Carbohydrate kinase
HWQ15_RS07690	COG4806	L-rhamnose isomerase
HWQ15_RS07695	COG0235	Class ii aldolase
HWQ15_RS07705	COG1129	ABC transporter
HWQ15_RS07710	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS07720	COG1454	alcohol dehydrogenase
HWQ15_RS07725	COG3254	rhamnose metabolic process
HWQ15_RS07730	COG2211	Major facilitator Superfamily
HWQ15_RS07750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HWQ15_RS07775	COG0437	4 iron, 4 sulfur cluster binding
HWQ15_RS07780	COG2864	formate dehydrogenase
HWQ15_RS07785	COG3058	Necessary for formate dehydrogenase activity
HWQ15_RS07795	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HWQ15_RS07800	COG0456	acetyltransferase
HWQ15_RS07815	COG1011	Hydrolase
HWQ15_RS07820	COG1349	DNA-binding transcription factor activity
HWQ15_RS07825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HWQ15_RS07835	COG3684	Belongs to the aldolase LacD family
HWQ15_RS07845	COG1501	Belongs to the glycosyl hydrolase 31 family
HWQ15_RS07860	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HWQ15_RS07875	COG3852	Histidine kinase
HWQ15_RS07890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HWQ15_RS07895	COG3078	GTPase activator activity
HWQ15_RS07915	COG0204	Acyl-transferase
HWQ15_RS07925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HWQ15_RS07930	COG3084	Protein conserved in bacteria
HWQ15_RS07935	COG0746	molybdenum cofactor guanylyltransferase activity
HWQ15_RS07940	COG1763	Mo-molybdopterin cofactor biosynthetic process
HWQ15_RS07965	COG2186	Transcriptional regulator
HWQ15_RS07970	COG0477	Major facilitator Superfamily
HWQ15_RS07975	COG1609	Transcriptional regulator
HWQ15_RS07980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HWQ15_RS07990	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS07995	COG1129	ABC transporter
HWQ15_RS08000	COG1869	D-ribose catabolic process
HWQ15_RS08005	COG3158	transport of potassium into the cell
HWQ15_RS08015	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HWQ15_RS08020	COG2502	aspartate--ammonia ligase
HWQ15_RS08025	COG1522	sequence-specific DNA binding
HWQ15_RS08030	COG0716	FMN binding
HWQ15_RS08035	COG0445	tRNA wobble uridine modification
HWQ15_RS08040	COG0357	Ribosomal RNA small subunit methyltransferase G
HWQ15_RS08045	COG3312	ion transport
HWQ15_RS08050	COG0356	it plays a direct role in the translocation of protons across the membrane
HWQ15_RS08060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HWQ15_RS08065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HWQ15_RS08070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HWQ15_RS08080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HWQ15_RS08085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HWQ15_RS08090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HWQ15_RS08100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HWQ15_RS08105	COG0573	inorganic phosphate transmembrane transporter activity
HWQ15_RS08110	COG0581	inorganic phosphate transmembrane transporter activity
HWQ15_RS08115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HWQ15_RS08120	COG0704	Plays a role in the regulation of phosphate uptake
HWQ15_RS08125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HWQ15_RS08130	COG2252	PERMEase
HWQ15_RS08135	COG0431	NADPH-dependent FMN reductase
HWQ15_RS08140	COG2091	lysine biosynthetic process via aminoadipic acid
HWQ15_RS08160	COG0706	membrane insertase activity
HWQ15_RS08185	COG0592	DNA-directed DNA polymerase activity
HWQ15_RS08190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HWQ15_RS08200	COG0583	DNA-binding transcription factor activity
HWQ15_RS08210	COG0561	phosphatase activity
HWQ15_RS08215	COG2186	Transcriptional regulator
HWQ15_RS08220	COG3734	2-keto-3-deoxy-galactonokinase
HWQ15_RS08225	COG0800	Aldolase
HWQ15_RS08230	COG4948	Mandelate Racemase Muconate Lactonizing
HWQ15_RS08235	COG2271	Major facilitator Superfamily
HWQ15_RS08240	COG0823	Involved in the tonB-independent uptake of proteins
HWQ15_RS08245	COG5645	(Lipo)protein
HWQ15_RS08255	COG0071	Belongs to the small heat shock protein (HSP20) family
HWQ15_RS08270	COG2985	domain, Protein
HWQ15_RS08275	COG2188	Transcriptional regulator
HWQ15_RS08290	COG2149	membrane
HWQ15_RS08310	COG2814	Major facilitator Superfamily
HWQ15_RS08330	COG4680	protein conserved in bacteria
HWQ15_RS08335	COG5499	transcription regulator containing HTH domain
HWQ15_RS08345	COG0028	Belongs to the TPP enzyme family
HWQ15_RS08350	COG0440	acetolactate synthase activity
HWQ15_RS08355	COG2197	response regulator
HWQ15_RS08375	COG0596	Alpha beta hydrolase
HWQ15_RS08390	COG0697	spore germination
HWQ15_RS08395	COG4580	involved in the transport of maltose and maltodextrins
HWQ15_RS08400	COG1447	Phosphotransferase system cellobiose-specific component IIA
HWQ15_RS08405	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS08410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS08410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS08420	COG1609	Transcriptional regulator
HWQ15_RS08435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS08440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS08450	COG0454	-acetyltransferase
HWQ15_RS08455	COG1309	transcriptional regulator
HWQ15_RS08465	COG1464	Belongs to the NlpA lipoprotein family
HWQ15_RS08490	COG3188	usher protein
HWQ15_RS08495	COG3121	Chaperone
HWQ15_RS08525	COG3188	usher protein
HWQ15_RS08550	COG2274	protein secretion by the type I secretion system
HWQ15_RS08585	COG3272	Protein of unknown function (DUF1722)
HWQ15_RS08590	COG2351	hydroxyisourate hydrolase activity
HWQ15_RS08595	COG0789	Transcriptional regulator
HWQ15_RS08620	COG3121	Chaperone
HWQ15_RS08685	COG2003	Belongs to the UPF0758 family
HWQ15_RS08735	COG0431	NADPH-dependent FMN reductase
HWQ15_RS08765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HWQ15_RS08790	COG0210	DNA helicase
HWQ15_RS08795	COG0582	viral genome integration into host DNA
HWQ15_RS08805	COG2211	Major facilitator Superfamily
HWQ15_RS08810	COG1501	Belongs to the glycosyl hydrolase 31 family
HWQ15_RS08820	COG2233	PERMEase
HWQ15_RS08825	COG0786	glutamate:sodium symporter activity
HWQ15_RS08830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HWQ15_RS08835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HWQ15_RS08840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HWQ15_RS08855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HWQ15_RS08860	COG2860	membrane
HWQ15_RS08865	COG3645	SOS response
HWQ15_RS08910	COG3561	AntA/AntB antirepressor
HWQ15_RS08935	COG1561	YicC-like family, N-terminal region
HWQ15_RS08945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HWQ15_RS08955	COG0756	dUTP diphosphatase activity
HWQ15_RS08960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HWQ15_RS08965	COG2003	Belongs to the UPF0758 family
HWQ15_RS08970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HWQ15_RS08975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HWQ15_RS08980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HWQ15_RS08985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HWQ15_RS08995	COG1519	Transferase
HWQ15_RS09000	COG1216	Glycosyl transferase, family 2
HWQ15_RS09005	COG0438	transferase activity, transferring glycosyl groups
HWQ15_RS09015	COG0859	PFAM glycosyl transferase family 9
HWQ15_RS09040	COG0859	PFAM glycosyl transferase family 9
HWQ15_RS09045	COG0859	PFAM glycosyl transferase family 9
HWQ15_RS09060	COG1063	alcohol dehydrogenase
HWQ15_RS09075	COG0463	Glycosyl transferase, family 2
HWQ15_RS09080	COG2861	carbohydrate metabolic process
HWQ15_RS09085	COG4942	peptidase
HWQ15_RS09090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HWQ15_RS09095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HWQ15_RS09100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HWQ15_RS09105	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HWQ15_RS09110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HWQ15_RS09120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HWQ15_RS09130	COG0248	Ppx GppA phosphatase
HWQ15_RS09140	COG3118	belongs to the thioredoxin family
HWQ15_RS09145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HWQ15_RS09150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HWQ15_RS09160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HWQ15_RS09165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HWQ15_RS09170	COG0456	acetyltransferase
HWQ15_RS09175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HWQ15_RS09180	COG2244	polysaccharide biosynthetic process
HWQ15_RS09195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HWQ15_RS09225	COG3071	HemY protein
HWQ15_RS09230	COG2959	enzyme of heme biosynthesis
HWQ15_RS09240	COG0181	hydroxymethylbilane synthase activity
HWQ15_RS09255	COG5567	small periplasmic lipoprotein
HWQ15_RS09275	COG1011	Hydrolase
HWQ15_RS09280	COG0210	DNA helicase
HWQ15_RS09300	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HWQ15_RS09310	COG1280	lysine exporter protein (LysE YggA)
HWQ15_RS09315	COG1280	lysine exporter protein (LysE YggA)
HWQ15_RS09320	COG2267	carboxylic ester hydrolase activity
HWQ15_RS09325	COG0561	phosphatase activity
HWQ15_RS09330	COG0697	spore germination
HWQ15_RS09335	COG0583	DNA-binding transcription factor activity
HWQ15_RS09345	COG0412	Dienelactone hydrolase
HWQ15_RS09355	COG1322	Protein conserved in bacteria
HWQ15_RS09360	COG2226	methyltransferase
HWQ15_RS09365	COG3165	ubiquinone biosynthetic process from chorismate
HWQ15_RS09370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HWQ15_RS09385	COG0805	protein transport
HWQ15_RS09390	COG0084	hydrolase, TatD family'
HWQ15_RS09400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HWQ15_RS09415	COG2944	sequence-specific DNA binding
HWQ15_RS09425	COG1278	Cold shock
HWQ15_RS09430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HWQ15_RS09440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HWQ15_RS09450	COG1609	Transcriptional regulator
HWQ15_RS09455	COG2885	chlorophyll binding
HWQ15_RS09460	COG0243	molybdopterin cofactor binding
HWQ15_RS09465	COG0456	acetyltransferase
HWQ15_RS09470	COG2818	Glycosylase
HWQ15_RS09475	COG5571	outer membrane autotransporter
HWQ15_RS09480	COG2223	nitrite transmembrane transporter activity
HWQ15_RS09495	COG0747	negative chemotaxis
HWQ15_RS09500	COG0601	transmembrane transport
HWQ15_RS09505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HWQ15_RS09510	COG0444	Belongs to the ABC transporter superfamily
HWQ15_RS09515	COG4608	Belongs to the ABC transporter superfamily
HWQ15_RS09520	COG1072	(Pantothenic acid kinase))
HWQ15_RS09555	COG0250	Participates in transcription elongation, termination and antitermination
HWQ15_RS09600	COG3706	GGDEF domain
HWQ15_RS09610	COG2022	thiamine diphosphate biosynthetic process
HWQ15_RS09615	COG2104	thiamine diphosphate biosynthetic process
HWQ15_RS09620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HWQ15_RS09635	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HWQ15_RS09645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HWQ15_RS09650	COG1515	deoxyribonuclease V activity
HWQ15_RS09670	COG0151	Belongs to the GarS family
HWQ15_RS09700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HWQ15_RS09710	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HWQ15_RS09740	COG1187	pseudouridine synthase activity
HWQ15_RS09755	COG0527	aspartate kinase activity
HWQ15_RS09780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HWQ15_RS09785	COG3223	Belongs to the PsiE family
HWQ15_RS09810	COG4580	involved in the transport of maltose and maltodextrins
HWQ15_RS09820	COG3161	chorismate lyase activity
HWQ15_RS09830	COG2937	Belongs to the GPAT DAPAT family
HWQ15_RS09835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HWQ15_RS09840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HWQ15_RS09845	COG0534	Mate efflux family protein
HWQ15_RS09850	COG3237	CsbD-like
HWQ15_RS09855	COG0735	belongs to the Fur family
HWQ15_RS09870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HWQ15_RS09880	COG0604	alcohol dehydrogenase
HWQ15_RS09885	COG0305	Participates in initiation and elongation during chromosome replication
HWQ15_RS09895	COG1448	Aminotransferase
HWQ15_RS09900	COG3700	Belongs to the class B bacterial acid phosphatase family
HWQ15_RS09910	COG2315	Protein conserved in bacteria
HWQ15_RS09920	COG0629	single-stranded DNA binding
HWQ15_RS09935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HWQ15_RS09945	COG0789	Transcriptional regulator
HWQ15_RS09955	COG2252	PERMEase
HWQ15_RS09960	COG0025	NhaP-type Na H and K H
HWQ15_RS09965	COG0583	DNA-binding transcription factor activity
HWQ15_RS09975	COG1346	cytolysis
HWQ15_RS09980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HWQ15_RS09985	COG3162	membrane
HWQ15_RS09995	COG1301	dicarboxylic acid transport
HWQ15_RS10000	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HWQ15_RS10015	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS10025	COG0191	fructose-bisphosphate aldolase activity
HWQ15_RS10040	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS10045	COG1129	ABC transporter
HWQ15_RS10050	COG4191	Histidine kinase
HWQ15_RS10050	COG0784	Response regulator, receiver
HWQ15_RS10060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HWQ15_RS10065	COG0456	acetyltransferase
HWQ15_RS10070	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HWQ15_RS10075	COG3454	Phosphonate metabolism
HWQ15_RS10080	COG4778	phosphonate C-P lyase system protein PhnL
HWQ15_RS10085	COG4107	phosphonate C-P lyase system protein PhnK
HWQ15_RS10090	COG3627	carbon phosphorus lyase activity
HWQ15_RS10095	COG3626	phosphonate metabolism
HWQ15_RS10100	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HWQ15_RS10105	COG3624	Phosphonate C-P lyase system protein PhnG
HWQ15_RS10110	COG2188	Transcriptional regulator
HWQ15_RS10115	COG3639	organic phosphonate transmembrane transporter activity
HWQ15_RS10120	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HWQ15_RS10130	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HWQ15_RS10135	COG2824	Alkylphosphonate utilization operon protein PhnA
HWQ15_RS10140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HWQ15_RS10160	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HWQ15_RS10190	COG1609	Transcriptional regulator
HWQ15_RS10200	COG2223	nitrite transmembrane transporter activity
HWQ15_RS10245	COG0071	Belongs to the small heat shock protein (HSP20) family
HWQ15_RS10250	COG0542	response to heat
HWQ15_RS10260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HWQ15_RS10310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HWQ15_RS10330	COG0210	DNA helicase
HWQ15_RS10340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HWQ15_RS10360	COG1309	transcriptional regulator
HWQ15_RS10375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HWQ15_RS10380	COG1027	Aspartate ammonia-lyase
HWQ15_RS10385	COG3030	protein affecting phage T7 exclusion by the F plasmid
HWQ15_RS10390	COG0531	amino acid
HWQ15_RS10400	COG0459	protein refolding
HWQ15_RS10405	COG0700	Nucleoside recognition
HWQ15_RS10410	COG3366	ferrous iron transmembrane transporter activity
HWQ15_RS10435	COG5510	response to toxic substance
HWQ15_RS10460	COG0583	DNA-binding transcription factor activity
HWQ15_RS10470	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HWQ15_RS10475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HWQ15_RS10480	COG1053	succinate dehydrogenase
HWQ15_RS10485	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HWQ15_RS10495	COG1511	domain protein
HWQ15_RS10495	COG3264	Mechanosensitive ion channel
HWQ15_RS10530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HWQ15_RS10535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HWQ15_RS10535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HWQ15_RS10540	COG0802	atpase or kinase
HWQ15_RS10550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HWQ15_RS10555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HWQ15_RS10560	COG1923	regulation of RNA biosynthetic process
HWQ15_RS10565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HWQ15_RS10570	COG0330	HflC and HflK could
HWQ15_RS10575	COG0330	HflC and HflK could
HWQ15_RS10580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HWQ15_RS10590	COG1959	2 iron, 2 sulfur cluster binding
HWQ15_RS10595	COG0557	exoribonuclease II activity
HWQ15_RS10600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HWQ15_RS10605	COG0477	Major facilitator Superfamily
HWQ15_RS10610	COG1960	acyl-CoA dehydrogenase activity
HWQ15_RS10625	COG3650	response to hydrogen peroxide
HWQ15_RS10630	COG1073	alpha beta
HWQ15_RS10645	COG3037	sugar-specific permease SgaT UlaA
HWQ15_RS10685	COG2965	DNA replication, synthesis of RNA primer
HWQ15_RS10690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HWQ15_RS10695	COG0359	binds to the 23S rRNA
HWQ15_RS10700	COG0697	spore germination
HWQ15_RS10705	COG3061	Opacity-associated protein A
HWQ15_RS10710	COG0545	Peptidyl-prolyl cis-trans isomerase
HWQ15_RS10715	COG1113	amino acid transport
HWQ15_RS10725	COG0840	transmembrane signaling receptor activity
HWQ15_RS10730	COG0697	spore germination
HWQ15_RS10740	COG2205	protein histidine kinase activity
HWQ15_RS10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS10745	COG3039	Transposase
HWQ15_RS10755	COG2197	response regulator
HWQ15_RS10775	COG0702	epimerase
HWQ15_RS10780	COG1733	regulation of RNA biosynthetic process
HWQ15_RS10790	COG1218	3'(2'),5'-bisphosphate nucleotidase
HWQ15_RS10795	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HWQ15_RS10805	COG1253	flavin adenine dinucleotide binding
HWQ15_RS10810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HWQ15_RS10815	COG0729	surface antigen
HWQ15_RS10820	COG2911	Protein conserved in bacteria
HWQ15_RS10825	COG2105	PFAM AIG2 family protein
HWQ15_RS10835	COG1879	ABC-type sugar transport system periplasmic component
HWQ15_RS10840	COG1129	ABC transporter
HWQ15_RS10845	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS10850	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS10865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HWQ15_RS10870	COG3028	Belongs to the UPF0307 family
HWQ15_RS10875	COG0312	modulator of DNA gyrase
HWQ15_RS10910	COG3964	amidohydrolase
HWQ15_RS10930	COG3711	transcriptional antiterminator
HWQ15_RS10930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS10935	COG0602	queuosine metabolic process
HWQ15_RS10945	COG0366	Alpha amylase catalytic
HWQ15_RS10950	COG1263	PTS System
HWQ15_RS10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS10955	COG1609	Transcriptional regulator
HWQ15_RS10965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HWQ15_RS10970	COG3397	chitin binding
HWQ15_RS10975	COG0251	oxidation-reduction process
HWQ15_RS10985	COG0540	Belongs to the ATCase OTCase family
HWQ15_RS11000	COG1438	arginine binding
HWQ15_RS11005	COG1288	antiporter activity
HWQ15_RS11020	COG2235	arginine
HWQ15_RS11025	COG2731	YhcH YjgK YiaL family protein
HWQ15_RS11030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HWQ15_RS11035	COG0129	dihydroxy-acid dehydratase activity
HWQ15_RS11040	COG2211	Major facilitator Superfamily
HWQ15_RS11045	COG3507	Belongs to the glycosyl hydrolase 43 family
HWQ15_RS11050	COG1414	Transcriptional regulator
HWQ15_RS11055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HWQ15_RS11130	COG3039	Transposase
HWQ15_RS11145	COG0582	viral genome integration into host DNA
HWQ15_RS11235	COG1609	Transcriptional regulator
HWQ15_RS11245	COG2211	Major facilitator Superfamily
HWQ15_RS11270	COG1335	isochorismatase
HWQ15_RS11285	COG2204	response regulator
HWQ15_RS11290	COG4191	Histidine kinase
HWQ15_RS11295	COG4566	intracellular signal transduction
HWQ15_RS11300	COG0740	serine-type endopeptidase activity
HWQ15_RS11305	COG2850	peptidyl-arginine hydroxylation
HWQ15_RS11330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HWQ15_RS11335	COG5457	Domain of unknown function (DUF1127)
HWQ15_RS11345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HWQ15_RS11360	COG0640	Transcriptional regulator
HWQ15_RS11380	COG2733	membrane
HWQ15_RS11390	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS11405	COG0523	cobalamin synthesis protein
HWQ15_RS11410	COG2879	small protein
HWQ15_RS11415	COG1966	Carbon starvation protein
HWQ15_RS11420	COG1349	DNA-binding transcription factor activity
HWQ15_RS11425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HWQ15_RS11430	COG2368	4-hydroxyphenylacetate
HWQ15_RS11450	COG3971	2-oxopent-4-enoate hydratase activity
HWQ15_RS11460	COG3384	dioxygenase
HWQ15_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS11470	COG0179	Fumarylacetoacetate (FAA) hydrolase
HWQ15_RS11475	COG1846	Transcriptional regulator
HWQ15_RS11480	COG0840	transmembrane signaling receptor activity
HWQ15_RS11500	COG1484	DNA-dependent DNA replication
HWQ15_RS11510	COG1764	response to oxidative stress
HWQ15_RS11515	COG1846	Transcriptional regulator
HWQ15_RS11520	COG3610	response to peptide
HWQ15_RS11525	COG2966	Psort location CytoplasmicMembrane, score
HWQ15_RS11530	COG2197	response regulator
HWQ15_RS11535	COG2197	response regulator
HWQ15_RS11540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HWQ15_RS11545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS11550	COG4114	ferric iron reductase
HWQ15_RS11555	COG3706	GGDEF domain
HWQ15_RS11580	COG2813	Specifically methylates the guanine in position
HWQ15_RS11585	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HWQ15_RS11590	COG0456	acetyltransferase
HWQ15_RS11595	COG1011	Hydrolase
HWQ15_RS11600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HWQ15_RS11605	COG2823	Periplasmic or secreted lipoprotein
HWQ15_RS11610	COG5487	UPF0391 membrane protein
HWQ15_RS11615	COG4667	esterase of the alpha-beta hydrolase superfamily
HWQ15_RS11620	COG0084	hydrolase, TatD family'
HWQ15_RS11625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HWQ15_RS11630	COG1328	CTP reductase activity
HWQ15_RS11660	COG3726	membrane protein affecting hemolysin expression
HWQ15_RS11665	COG0560	Phosphoserine phosphatase
HWQ15_RS11690	COG0488	(ABC) transporter
HWQ15_RS11695	COG0741	lytic transglycosylase activity
HWQ15_RS11700	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
HWQ15_RS11705	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HWQ15_RS11710	COG0406	alpha-ribazole phosphatase activity
HWQ15_RS11715	COG2207	Transcriptional regulator
HWQ15_RS11715	COG3708	Transcriptional regulator
HWQ15_RS11720	COG3045	CreA protein
HWQ15_RS11725	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS11735	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HWQ15_RS11745	COG0460	homoserine dehydrogenase
HWQ15_RS11745	COG0527	aspartate kinase activity
HWQ15_RS11755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HWQ15_RS11770	COG1115	amino acid carrier protein
HWQ15_RS11780	COG0521	Mo-molybdopterin cofactor biosynthetic process
HWQ15_RS11785	COG0477	Major facilitator Superfamily
HWQ15_RS11790	COG1584	GPR1 FUN34 yaaH family protein
HWQ15_RS11795	COG0443	Heat shock 70 kDa protein
HWQ15_RS11805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HWQ15_RS11810	COG0583	DNA-binding transcription factor activity
HWQ15_RS11815	COG0268	Binds directly to 16S ribosomal RNA
HWQ15_RS11825	COG0196	riboflavin kinase activity
HWQ15_RS11840	COG1047	Peptidyl-prolyl cis-trans
HWQ15_RS11845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HWQ15_RS11855	COG0505	Belongs to the CarA family
HWQ15_RS11880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HWQ15_RS11880	COG0475	glutathione-regulated potassium exporter activity
HWQ15_RS11890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HWQ15_RS11895	COG2967	ApaG domain
HWQ15_RS11905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HWQ15_RS11910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HWQ15_RS11915	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HWQ15_RS11920	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HWQ15_RS11925	COG0564	pseudouridine synthase activity
HWQ15_RS11930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HWQ15_RS11935	COG0417	DNA replication proofreading
HWQ15_RS11940	COG0235	Class ii aldolase
HWQ15_RS11945	COG2160	L-arabinose isomerase activity
HWQ15_RS11950	COG1069	ribulokinase activity
HWQ15_RS11960	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS11970	COG1178	ABC-type Fe3 transport system permease component
HWQ15_RS11990	COG2814	Major facilitator Superfamily
HWQ15_RS12015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HWQ15_RS12030	COG0028	Belongs to the TPP enzyme family
HWQ15_RS12035	COG0440	acetolactate synthase activity
HWQ15_RS12040	COG1609	Transcriptional regulator
HWQ15_RS12045	COG2001	Belongs to the MraZ family
HWQ15_RS12060	COG0768	penicillin binding
HWQ15_RS12065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HWQ15_RS12070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HWQ15_RS12075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HWQ15_RS12085	COG0772	Belongs to the SEDS family
HWQ15_RS12100	COG1181	Belongs to the D-alanine--D-alanine ligase family
HWQ15_RS12110	COG0849	cell division
HWQ15_RS12115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HWQ15_RS12120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HWQ15_RS12130	COG0653	protein targeting
HWQ15_RS12135	COG0494	nUDIX hydrolase
HWQ15_RS12140	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HWQ15_RS12145	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HWQ15_RS12155	COG0516	GMP reductase activity
HWQ15_RS12160	COG1459	type II secretion system
HWQ15_RS12165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HWQ15_RS12170	COG4969	Belongs to the N-Me-Phe pilin family
HWQ15_RS12180	COG3023	N-Acetylmuramoyl-L-alanine amidase
HWQ15_RS12185	COG3725	Membrane protein required for beta-lactamase induction
HWQ15_RS12190	COG3940	Belongs to the glycosyl hydrolase 43 family
HWQ15_RS12195	COG2211	Major facilitator Superfamily
HWQ15_RS12200	COG1113	amino acid transport
HWQ15_RS12205	COG2186	Transcriptional regulator
HWQ15_RS12210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HWQ15_RS12215	COG0508	dehydrogenase complex catalyzes the overall conversion of
HWQ15_RS12220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HWQ15_RS12230	COG3064	Membrane
HWQ15_RS12245	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HWQ15_RS12250	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HWQ15_RS12265	COG4993	Dehydrogenase
HWQ15_RS12275	COG0288	reversible hydration of carbon dioxide
HWQ15_RS12285	COG0842	Transport permease protein
HWQ15_RS12295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS12300	COG0726	polysaccharide deacetylase
HWQ15_RS12310	COG3539	Fimbrial protein
HWQ15_RS12320	COG3539	Fimbrial protein
HWQ15_RS12325	COG3188	usher protein
HWQ15_RS12330	COG3121	Chaperone
HWQ15_RS12340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HWQ15_RS12345	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HWQ15_RS12355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HWQ15_RS12360	COG0617	tRNA 3'-terminal CCA addition
HWQ15_RS12365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HWQ15_RS12375	COG1489	DNA binding
HWQ15_RS12380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HWQ15_RS12385	COG1643	Atp-dependent helicase
HWQ15_RS12390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HWQ15_RS12395	COG4774	siderophore transport
HWQ15_RS12400	COG1120	ATPase activity
HWQ15_RS12405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HWQ15_RS12410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS12415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HWQ15_RS12425	COG0316	Belongs to the HesB IscA family
HWQ15_RS12430	COG2860	membrane
HWQ15_RS12440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HWQ15_RS12445	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HWQ15_RS12450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HWQ15_RS12455	COG3835	regulator
HWQ15_RS12500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HWQ15_RS12510	COG0575	Belongs to the CDS family
HWQ15_RS12515	COG0750	zinc metalloprotease
HWQ15_RS12520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HWQ15_RS12535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HWQ15_RS12545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HWQ15_RS12550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HWQ15_RS12560	COG0825	malonyl-CoA metabolic process
HWQ15_RS12570	COG0346	lactoylglutathione lyase activity
HWQ15_RS12575	COG0037	tRNA processing
HWQ15_RS12580	COG4568	rho-dependent transcription termination
HWQ15_RS12595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HWQ15_RS12600	COG3015	lipoprotein NlpE involved in copper resistance
HWQ15_RS12610	COG1720	tRNA m6t6A37 methyltransferase activity
HWQ15_RS12620	COG1464	Belongs to the NlpA lipoprotein family
HWQ15_RS12625	COG2011	ABC-type metal ion transport system permease component
HWQ15_RS12635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HWQ15_RS12675	COG0583	DNA-binding transcription factor activity
HWQ15_RS12680	COG2814	Major facilitator Superfamily
HWQ15_RS12685	COG3021	interspecies interaction between organisms
HWQ15_RS12690	COG2226	methyltransferase
HWQ15_RS12695	COG1388	LysM domain
HWQ15_RS12695	COG0741	lytic transglycosylase activity
HWQ15_RS12700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HWQ15_RS12705	COG2226	methyltransferase
HWQ15_RS12730	COG0444	Belongs to the ABC transporter superfamily
HWQ15_RS12735	COG4608	Belongs to the ABC transporter superfamily
HWQ15_RS12760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HWQ15_RS12775	COG0121	glutamine amidotransferase
HWQ15_RS12780	COG3034	peptidoglycan biosynthetic process
HWQ15_RS12795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HWQ15_RS12800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HWQ15_RS12815	COG2991	Protein conserved in bacteria
HWQ15_RS12820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HWQ15_RS12825	COG2195	Cleaves the N-terminal amino acid of tripeptides
HWQ15_RS12845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HWQ15_RS12850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HWQ15_RS12855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HWQ15_RS12885	COG0582	viral genome integration into host DNA
HWQ15_RS12945	COG0582	viral genome integration into host DNA
HWQ15_RS12970	COG0702	epimerase
HWQ15_RS12980	COG0667	Aldo Keto reductase
HWQ15_RS12985	COG0656	L-ascorbic acid biosynthetic process
HWQ15_RS13025	COG5002	protein histidine kinase activity
HWQ15_RS13035	COG0667	Aldo Keto reductase
HWQ15_RS13045	COG0778	Nitroreductase
HWQ15_RS13050	COG2814	Major facilitator Superfamily
HWQ15_RS13065	COG5001	Diguanylate cyclase
HWQ15_RS13065	COG3300	MHYT domain
HWQ15_RS13085	COG0628	permease
HWQ15_RS13090	COG0833	amino acid
HWQ15_RS13095	COG2040	homocysteine
HWQ15_RS13100	COG4521	taurine ABC transporter
HWQ15_RS13105	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HWQ15_RS13110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HWQ15_RS13115	COG2175	clavaminate synthase activity
HWQ15_RS13125	COG0113	porphobilinogen synthase activity
HWQ15_RS13140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HWQ15_RS13145	COG1335	isochorismatase
HWQ15_RS13150	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HWQ15_RS13195	COG3706	GGDEF domain
HWQ15_RS13200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HWQ15_RS13205	COG1671	Belongs to the UPF0178 family
HWQ15_RS13210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HWQ15_RS13220	COG4126	flavin adenine dinucleotide binding
HWQ15_RS13225	COG3123	guanosine phosphorylase activity
HWQ15_RS13235	COG1940	carbohydrate kinase activity
HWQ15_RS13240	COG0419	ATPase involved in DNA repair
HWQ15_RS13245	COG0420	3'-5' exonuclease activity
HWQ15_RS13255	COG5002	protein histidine kinase activity
HWQ15_RS13270	COG0366	Alpha amylase catalytic
HWQ15_RS13285	COG0450	alkyl hydroperoxide reductase
HWQ15_RS13290	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HWQ15_RS13305	COG1862	Preprotein translocase
HWQ15_RS13310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HWQ15_RS13315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HWQ15_RS13330	COG4238	major outer membrane lipoprotein
HWQ15_RS13335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HWQ15_RS13340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HWQ15_RS13340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HWQ15_RS13345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HWQ15_RS13350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HWQ15_RS13355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HWQ15_RS13360	COG0667	Aldo Keto reductase
HWQ15_RS13365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HWQ15_RS13370	COG0142	geranyltranstransferase activity
HWQ15_RS13385	COG0693	protein deglycase activity
HWQ15_RS13400	COG2814	Major facilitator Superfamily
HWQ15_RS13405	COG0235	Class ii aldolase
HWQ15_RS13415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HWQ15_RS13425	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS13430	COG1129	ABC transporter
HWQ15_RS13450	COG0109	protoheme IX farnesyltransferase activity
HWQ15_RS13455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HWQ15_RS13460	COG1845	cytochrome c oxidase, subunit III
HWQ15_RS13465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HWQ15_RS13470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HWQ15_RS13475	COG2223	nitrite transmembrane transporter activity
HWQ15_RS13480	COG3056	Lipoprotein
HWQ15_RS13485	COG0271	Belongs to the BolA IbaG family
HWQ15_RS13490	COG0544	peptidyl-prolyl cis-trans isomerase activity
HWQ15_RS13505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HWQ15_RS13510	COG0776	regulation of translation
HWQ15_RS13515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HWQ15_RS13520	COG1555	photosystem II stabilization
HWQ15_RS13525	COG0824	Thioesterase
HWQ15_RS13530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HWQ15_RS13535	COG4533	DNA binding
HWQ15_RS13540	COG0561	phosphatase activity
HWQ15_RS13550	COG1522	sequence-specific DNA binding
HWQ15_RS13555	COG1132	(ABC) transporter
HWQ15_RS13560	COG1132	(ABC) transporter
HWQ15_RS13565	COG0347	Belongs to the P(II) protein family
HWQ15_RS13570	COG0004	ammonium transporteR
HWQ15_RS13575	COG1946	Acyl-CoA thioesterase
HWQ15_RS13580	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HWQ15_RS13585	COG3695	enzyme binding
HWQ15_RS13605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HWQ15_RS13610	COG2364	Membrane
HWQ15_RS13615	COG1609	Transcriptional regulator
HWQ15_RS13625	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HWQ15_RS13635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HWQ15_RS13655	COG0110	maltose O-acetyltransferase activity
HWQ15_RS13670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS13680	COG1309	transcriptional regulator
HWQ15_RS13685	COG3264	Mechanosensitive ion channel
HWQ15_RS13685	COG1196	nuclear chromosome segregation
HWQ15_RS13695	COG3923	Primosomal replication protein n
HWQ15_RS13700	COG2832	Protein of unknown function (DUF454)
HWQ15_RS13705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HWQ15_RS13715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HWQ15_RS13720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HWQ15_RS13725	COG0326	Molecular chaperone. Has ATPase activity
HWQ15_RS13735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HWQ15_RS13740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HWQ15_RS13745	COG4651	solute:proton antiporter activity
HWQ15_RS13745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HWQ15_RS13750	COG2223	nitrite transmembrane transporter activity
HWQ15_RS13760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HWQ15_RS13765	COG3735	TraB family
HWQ15_RS13770	COG2217	Heavy metal translocating P-type atpase
HWQ15_RS13780	COG1585	Membrane protein implicated in regulation of membrane protease activity
HWQ15_RS13785	COG0330	HflC and HflK could
HWQ15_RS13795	COG4619	ABC transporter
HWQ15_RS13800	COG0390	transport system, permease component
HWQ15_RS13805	COG3118	belongs to the thioredoxin family
HWQ15_RS13810	COG0300	oxidoreductase activity
HWQ15_RS13815	COG2755	lipolytic protein G-D-S-L family
HWQ15_RS13820	COG4181	ATPase activity
HWQ15_RS13825	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HWQ15_RS13830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HWQ15_RS13840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HWQ15_RS13845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HWQ15_RS13850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HWQ15_RS13855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HWQ15_RS13865	COG1988	membrane-bound metal-dependent
HWQ15_RS13870	COG1609	Transcriptional regulator
HWQ15_RS13875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS13875	COG1263	PTS System
HWQ15_RS13875	COG2190	(PTS) system
HWQ15_RS13880	COG2501	S4 domain
HWQ15_RS13950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HWQ15_RS13970	COG1113	amino acid transport
HWQ15_RS13975	COG2211	Major facilitator Superfamily
HWQ15_RS13990	COG1609	Transcriptional regulator
HWQ15_RS13995	COG0668	transmembrane transport
HWQ15_RS14000	COG0477	Major facilitator Superfamily
HWQ15_RS14015	COG0778	Nitroreductase
HWQ15_RS14020	COG2315	Protein conserved in bacteria
HWQ15_RS14035	COG2207	Transcriptional regulator
HWQ15_RS14040	COG4774	siderophore transport
HWQ15_RS14070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HWQ15_RS14085	COG3209	COG3209 Rhs family protein
HWQ15_RS14115	COG3209	COG3209 Rhs family protein
HWQ15_RS14130	COG4680	protein conserved in bacteria
HWQ15_RS14145	COG1278	Cold shock
HWQ15_RS14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HWQ15_RS14215	COG1121	(ABC) transporter
HWQ15_RS14220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HWQ15_RS14225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HWQ15_RS14230	COG2977	Belongs to the P-Pant transferase superfamily
HWQ15_RS14235	COG4771	TonB-dependent receptor
HWQ15_RS14240	COG2382	esterase
HWQ15_RS14245	COG3251	PFAM MbtH domain protein
HWQ15_RS14250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HWQ15_RS14250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HWQ15_RS14255	COG1120	ATPase activity
HWQ15_RS14260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS14265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS14275	COG4592	Periplasmic binding protein
HWQ15_RS14280	COG1169	isochorismate synthase
HWQ15_RS14285	COG1021	2,3-dihydroxybenzoate-AMP ligase
HWQ15_RS14290	COG3433	isochorismatase activity
HWQ15_RS14290	COG1535	isochorismatase
HWQ15_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS14300	COG2050	protein possibly involved in aromatic compounds catabolism
HWQ15_RS14310	COG0700	Nucleoside recognition
HWQ15_RS14315	COG3366	ferrous iron transmembrane transporter activity
HWQ15_RS14325	COG2879	small protein
HWQ15_RS14340	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS14345	COG0371	Dehydrogenase
HWQ15_RS14350	COG1129	ABC transporter
HWQ15_RS14355	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS14370	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HWQ15_RS14385	COG3423	Transcriptional regulator
HWQ15_RS14400	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HWQ15_RS14405	COG0235	Class ii aldolase
HWQ15_RS14410	COG0436	Aminotransferase
HWQ15_RS14415	COG1475	DNA binding
HWQ15_RS14420	COG3969	phosphoadenosine phosphosulfate
HWQ15_RS14425	COG0583	DNA-binding transcription factor activity
HWQ15_RS14445	COG1063	alcohol dehydrogenase
HWQ15_RS14450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HWQ15_RS14460	COG3719	Belongs to the RNase T2 family
HWQ15_RS14465	COG3069	C4-dicarboxylate transmembrane transporter activity
HWQ15_RS14485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS14490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS14510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HWQ15_RS14515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HWQ15_RS14520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HWQ15_RS14525	COG0583	DNA-binding transcription factor activity
HWQ15_RS14530	COG0321	lipoyl(octanoyl) transferase activity
HWQ15_RS14540	COG1686	Belongs to the peptidase S11 family
HWQ15_RS14545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HWQ15_RS14550	COG0772	Belongs to the SEDS family
HWQ15_RS14555	COG0768	penicillin binding
HWQ15_RS14565	COG0799	negative regulation of ribosome biogenesis
HWQ15_RS14575	COG1466	dna polymerase III delta subunit
HWQ15_RS14590	COG2888	peptidyl-tyrosine sulfation
HWQ15_RS14595	COG1957	nucleoside hydrolase
HWQ15_RS14600	COG1126	abc transporter atp-binding protein
HWQ15_RS14605	COG0765	amino acid transport
HWQ15_RS14610	COG0765	amino acid transport
HWQ15_RS14630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HWQ15_RS14635	COG1702	phosphate starvation-inducible protein PhoH
HWQ15_RS14640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HWQ15_RS14645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HWQ15_RS14685	COG0367	asparagine synthase
HWQ15_RS14690	COG0647	UMP catabolic process
HWQ15_RS14695	COG1940	carbohydrate kinase activity
HWQ15_RS14695	COG1846	Transcriptional regulator
HWQ15_RS14700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HWQ15_RS14710	COG1263	PTS System
HWQ15_RS14710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS14710	COG2190	(PTS) system
HWQ15_RS14715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HWQ15_RS14730	COG0735	belongs to the Fur family
HWQ15_RS14750	COG0596	Alpha beta hydrolase
HWQ15_RS14755	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HWQ15_RS14760	COG0033	Phosphoglucomutase
HWQ15_RS14765	COG0531	amino acid
HWQ15_RS14770	COG1982	Orn Lys Arg decarboxylase major
HWQ15_RS14780	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS14790	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HWQ15_RS14795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HWQ15_RS14800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HWQ15_RS14820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HWQ15_RS14825	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HWQ15_RS14830	COG1984	allophanate hydrolase subunit 2
HWQ15_RS14840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HWQ15_RS14845	COG0372	Belongs to the citrate synthase family
HWQ15_RS14850	COG2009	succinate dehydrogenase
HWQ15_RS14855	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HWQ15_RS14860	COG1053	succinate dehydrogenase
HWQ15_RS14865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HWQ15_RS14870	COG0567	Dehydrogenase, E1 component
HWQ15_RS14875	COG0508	dehydrogenase complex catalyzes the overall conversion of
HWQ15_RS14880	COG0045	succinate-CoA ligase (ADP-forming) activity
HWQ15_RS14885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HWQ15_RS14890	COG2188	Transcriptional regulator
HWQ15_RS14895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS14895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HWQ15_RS14895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HWQ15_RS14900	COG0383	alpha-mannosidase activity
HWQ15_RS14905	COG1271	oxidase subunit
HWQ15_RS14910	COG1294	oxidase, subunit
HWQ15_RS14915	COG4890	Cyd operon protein YbgT
HWQ15_RS14920	COG3790	cyd operon protein YbgE
HWQ15_RS14925	COG0824	Thioesterase
HWQ15_RS14930	COG0811	peptide transport
HWQ15_RS14935	COG0848	biopolymer transport protein
HWQ15_RS14940	COG3064	Membrane
HWQ15_RS14945	COG0823	Involved in the tonB-independent uptake of proteins
HWQ15_RS14950	COG2885	chlorophyll binding
HWQ15_RS14955	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HWQ15_RS14990	COG3201	nicotinamide mononucleotide transporter
HWQ15_RS14995	COG1230	cation diffusion facilitator family transporter
HWQ15_RS15005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HWQ15_RS15015	COG2017	converts alpha-aldose to the beta-anomer
HWQ15_RS15020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HWQ15_RS15025	COG1085	galactose-1-phosphate uridylyltransferase
HWQ15_RS15030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HWQ15_RS15035	COG1119	ATPase activity
HWQ15_RS15040	COG3585	molybdate ion transport
HWQ15_RS15040	COG2005	Transcriptional regulator
HWQ15_RS15050	COG0725	ABC transporter, periplasmic molybdate-binding protein
HWQ15_RS15055	COG4149	molybdate abc transporter
HWQ15_RS15065	COG0561	phosphatase activity
HWQ15_RS15070	COG2706	6-phosphogluconolactonase activity
HWQ15_RS15075	COG4677	pectinesterase activity
HWQ15_RS15085	COG0010	Belongs to the arginase family
HWQ15_RS15095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HWQ15_RS15100	COG2986	histidine ammonia-lyase
HWQ15_RS15105	COG1881	PFAM PEBP family protein
HWQ15_RS15110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HWQ15_RS15115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HWQ15_RS15120	COG0156	8-amino-7-oxononanoate synthase activity
HWQ15_RS15125	COG2226	methyltransferase
HWQ15_RS15155	COG0521	Mo-molybdopterin cofactor biosynthetic process
HWQ15_RS15160	COG0315	cyclic pyranopterin monophosphate synthase activity
HWQ15_RS15165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HWQ15_RS15170	COG0314	molybdopterin synthase activity
HWQ15_RS15175	COG0670	Belongs to the BI1 family
HWQ15_RS15180	COG0392	lysyltransferase activity
HWQ15_RS15185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HWQ15_RS15190	COG3568	Endonuclease Exonuclease Phosphatase
HWQ15_RS15200	COG0842	Transport permease protein
HWQ15_RS15205	COG0842	Transport permease protein
HWQ15_RS15210	COG1131	(ABC) transporter
HWQ15_RS15215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS15220	COG1309	transcriptional regulator
HWQ15_RS15225	COG0513	Belongs to the DEAD box helicase family
HWQ15_RS15250	COG3121	Chaperone
HWQ15_RS15255	COG3539	Fimbrial protein
HWQ15_RS15260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HWQ15_RS15270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HWQ15_RS15280	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HWQ15_RS15285	COG0668	transmembrane transport
HWQ15_RS15290	COG1126	abc transporter atp-binding protein
HWQ15_RS15295	COG0765	amino acid transport
HWQ15_RS15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS15305	COG0783	Belongs to the Dps family
HWQ15_RS15315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HWQ15_RS15320	COG2194	sulfuric ester hydrolase activity
HWQ15_RS15330	COG1321	iron dependent repressor
HWQ15_RS15335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HWQ15_RS15340	COG1566	PFAM secretion protein HlyD family protein
HWQ15_RS15345	COG2814	Major facilitator Superfamily
HWQ15_RS15355	COG0667	Aldo Keto reductase
HWQ15_RS15360	COG2723	6-phospho-beta-galactosidase activity
HWQ15_RS15365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS15370	COG2188	Transcriptional regulator
HWQ15_RS15375	COG1376	ErfK ybiS ycfS ynhG family protein
HWQ15_RS15380	COG0488	(ABC) transporter
HWQ15_RS15390	COG2271	Major facilitator Superfamily
HWQ15_RS15395	COG1609	Transcriptional regulator
HWQ15_RS15405	COG0561	phosphatase activity
HWQ15_RS15410	COG1882	Formate acetyltransferase
HWQ15_RS15415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HWQ15_RS15420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HWQ15_RS15430	COG0303	'Molybdopterin
HWQ15_RS15435	COG1446	asparaginase
HWQ15_RS15470	COG2133	pyrroloquinoline quinone binding
HWQ15_RS15475	COG0625	glutathione transferase activity
HWQ15_RS15480	COG1686	Belongs to the peptidase S11 family
HWQ15_RS15485	COG1349	DNA-binding transcription factor activity
HWQ15_RS15490	COG0671	phosphoesterase, PA-phosphatase related
HWQ15_RS15500	COG2814	Major facilitator Superfamily
HWQ15_RS15505	COG0561	phosphatase activity
HWQ15_RS15510	COG0738	Major facilitator superfamily
HWQ15_RS15515	COG3226	Transcriptional regulator
HWQ15_RS15520	COG1393	Belongs to the ArsC family
HWQ15_RS15525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HWQ15_RS15530	COG0640	Transcriptional regulator
HWQ15_RS15560	COG0778	Nitroreductase
HWQ15_RS15575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HWQ15_RS15580	COG3842	ATPase activity
HWQ15_RS15585	COG1176	ABC-type spermidine putrescine transport system, permease component I
HWQ15_RS15590	COG1177	transmembrane transport
HWQ15_RS15600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HWQ15_RS15605	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS15610	COG5002	protein histidine kinase activity
HWQ15_RS15615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS15620	COG4160	amino acid transport
HWQ15_RS15625	COG4215	(ABC) transporter
HWQ15_RS15630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS15635	COG1126	abc transporter atp-binding protein
HWQ15_RS15645	COG0393	Putative heavy-metal-binding
HWQ15_RS15650	COG3023	N-Acetylmuramoyl-L-alanine amidase
HWQ15_RS15670	COG3031	protein transport across the cell outer membrane
HWQ15_RS15675	COG1450	Type ii and iii secretion system protein
HWQ15_RS15680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HWQ15_RS15685	COG1459	type II secretion system
HWQ15_RS15690	COG2165	general secretion pathway protein
HWQ15_RS15700	COG2165	general secretion pathway protein
HWQ15_RS15725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HWQ15_RS15740	COG3397	chitin binding
HWQ15_RS15745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HWQ15_RS15750	COG0702	epimerase
HWQ15_RS15755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HWQ15_RS15760	COG0028	Belongs to the TPP enzyme family
HWQ15_RS15765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HWQ15_RS15770	COG1151	hydroxylamine reductase activity
HWQ15_RS15775	COG2431	L-lysine efflux transmembrane transporter activity
HWQ15_RS15785	COG3593	DNA synthesis involved in DNA repair
HWQ15_RS15790	COG2990	Protein conserved in bacteria
HWQ15_RS15795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HWQ15_RS15805	COG1278	Cold shock
HWQ15_RS15810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HWQ15_RS15815	COG0542	response to heat
HWQ15_RS15825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HWQ15_RS15830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HWQ15_RS15835	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HWQ15_RS15840	COG4988	ABC transporter
HWQ15_RS15845	COG0492	ferredoxin-NADP+ reductase activity
HWQ15_RS15855	COG1178	ABC-type Fe3 transport system permease component
HWQ15_RS15855	COG1674	ftsk spoiiie
HWQ15_RS15860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HWQ15_RS15865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HWQ15_RS15870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HWQ15_RS15875	COG0243	molybdopterin cofactor binding
HWQ15_RS15880	COG0437	4 iron, 4 sulfur cluster binding
HWQ15_RS15885	COG3302	dmso reductase anchor subunit
HWQ15_RS15890	COG0477	Major facilitator Superfamily
HWQ15_RS15900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HWQ15_RS15905	COG1882	Formate acetyltransferase
HWQ15_RS15910	COG2116	formate transmembrane transporter activity
HWQ15_RS15915	COG1944	ATP diphosphatase activity
HWQ15_RS15920	COG2323	membrane
HWQ15_RS15925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HWQ15_RS15930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HWQ15_RS15935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HWQ15_RS15940	COG0539	negative regulation of cytoplasmic translation
HWQ15_RS15945	COG0776	regulation of translation
HWQ15_RS15950	COG2333	competence protein COMEC
HWQ15_RS15950	COG0658	competence protein
HWQ15_RS15955	COG1132	(ABC) transporter
HWQ15_RS15965	COG3214	Protein conserved in bacteria
HWQ15_RS15970	COG2835	tetraacyldisaccharide 4'-kinase activity
HWQ15_RS15975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HWQ15_RS15980	COG3173	Aminoglycoside phosphotransferase
HWQ15_RS15985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HWQ15_RS15990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HWQ15_RS16000	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HWQ15_RS16005	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HWQ15_RS16010	COG2989	Protein conserved in bacteria
HWQ15_RS16015	COG3108	Peptidase M15
HWQ15_RS16020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HWQ15_RS16025	COG1448	Aminotransferase
HWQ15_RS16035	COG0017	Asparaginyl-tRNA synthetase
HWQ15_RS16040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HWQ15_RS16045	COG0308	aminopeptidase N
HWQ15_RS16055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HWQ15_RS16060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS16065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HWQ15_RS16070	COG0431	NADPH-dependent FMN reductase
HWQ15_RS16075	COG0167	dihydroorotate dehydrogenase activity
HWQ15_RS16085	COG0633	Ferredoxin
HWQ15_RS16085	COG3217	Mosc domain protein beta barrel domain protein
HWQ15_RS16090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HWQ15_RS16090	COG0116	Belongs to the methyltransferase superfamily
HWQ15_RS16095	COG0488	(ABC) transporter
HWQ15_RS16100	COG2995	paraquat-inducible protein a
HWQ15_RS16105	COG3008	intermembrane lipid transfer
HWQ15_RS16105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HWQ15_RS16110	COG3009	Protein conserved in bacteria
HWQ15_RS16115	COG3130	regulation of translation
HWQ15_RS16125	COG1067	ATP-dependent peptidase activity
HWQ15_RS16130	COG3120	sequence-specific DNA binding
HWQ15_RS16140	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
HWQ15_RS16145	COG3070	regulator of competence-specific genes
HWQ15_RS16150	COG1289	transmembrane transporter activity
HWQ15_RS16155	COG3304	Inner membrane component domain
HWQ15_RS16160	COG0210	DNA helicase
HWQ15_RS16165	COG1803	Methylglyoxal synthase
HWQ15_RS16170	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HWQ15_RS16175	COG1832	CoA-binding protein
HWQ15_RS16185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HWQ15_RS16190	COG1254	Belongs to the acylphosphatase family
HWQ15_RS16200	COG0670	Belongs to the BI1 family
HWQ15_RS16220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS16230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HWQ15_RS16230	COG3264	Mechanosensitive ion channel
HWQ15_RS16250	COG2239	Acts as a magnesium transporter
HWQ15_RS16255	COG0586	Pfam SNARE associated Golgi protein
HWQ15_RS16275	COG3729	General stress protein
HWQ15_RS16285	COG2233	PERMEase
HWQ15_RS16290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HWQ15_RS16295	COG0778	Nitroreductase
HWQ15_RS16300	COG2267	carboxylic ester hydrolase activity
HWQ15_RS16305	COG0251	oxidation-reduction process
HWQ15_RS16310	COG1335	isochorismatase
HWQ15_RS16315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS16320	COG1309	transcriptional regulator
HWQ15_RS16330	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HWQ15_RS16330	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HWQ15_RS16330	COG0506	proline dehydrogenase activity
HWQ15_RS16335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HWQ15_RS16345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HWQ15_RS16365	COG1702	phosphate starvation-inducible protein PhoH
HWQ15_RS16370	COG1115	amino acid carrier protein
HWQ15_RS16385	COG1335	isochorismatase
HWQ15_RS16395	COG0583	DNA-binding transcription factor activity
HWQ15_RS16410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HWQ15_RS16415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HWQ15_RS16420	COG3381	protein complex oligomerization
HWQ15_RS16470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HWQ15_RS16525	COG1560	Kdo2-lipid A biosynthetic process
HWQ15_RS16535	COG2353	YceI-like domain
HWQ15_RS16540	COG3038	cytochrome b561
HWQ15_RS16565	COG0418	dihydroorotase activity
HWQ15_RS16575	COG0477	Major facilitator Superfamily
HWQ15_RS16580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS16585	COG3132	Protein of unknown function, DUF480
HWQ15_RS16620	COG1558	bacterial-type flagellum-dependent cell motility
HWQ15_RS16630	COG1749	Flagellar hook protein flgE
HWQ15_RS16640	COG4786	Flagellar basal body rod
HWQ15_RS16660	COG1256	bacterial-type flagellum assembly
HWQ15_RS16670	COG2814	Major facilitator Superfamily
HWQ15_RS16675	COG0583	DNA-binding transcription factor activity
HWQ15_RS16685	COG0564	pseudouridine synthase activity
HWQ15_RS16690	COG0424	maF-like protein
HWQ15_RS16700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HWQ15_RS16705	COG0416	fatty acid biosynthetic process
HWQ15_RS16710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HWQ15_RS16725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HWQ15_RS16730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HWQ15_RS16735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HWQ15_RS16740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HWQ15_RS16750	COG0470	DNA polymerase III
HWQ15_RS16755	COG0084	hydrolase, TatD family'
HWQ15_RS16765	COG4773	Receptor
HWQ15_RS16770	COG0537	adenosine 5'-monophosphoramidase activity
HWQ15_RS16775	COG5633	Lipoprotein
HWQ15_RS16780	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HWQ15_RS16795	COG3150	esterase
HWQ15_RS16800	COG1252	NADH dehydrogenase
HWQ15_RS16805	COG3134	Outer membrane lipoprotein
HWQ15_RS16810	COG1309	transcriptional regulator
HWQ15_RS16820	COG1388	LysM domain
HWQ15_RS16820	COG1376	ErfK ybiS ycfS ynhG family protein
HWQ15_RS16825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HWQ15_RS16830	COG4763	Acyl-transferase
HWQ15_RS16835	COG4591	ABC-type transport system involved in lipoprotein release permease component
HWQ15_RS16840	COG1136	(ABC) transporter
HWQ15_RS16845	COG4591	ABC-type transport system involved in lipoprotein release permease component
HWQ15_RS16885	COG1943	Transposase
HWQ15_RS16890	COG2850	peptidyl-arginine hydroxylation
HWQ15_RS16895	COG2205	protein histidine kinase activity
HWQ15_RS16910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HWQ15_RS16915	COG2915	High frequency lysogenization protein hflD homolog
HWQ15_RS16930	COG1187	pseudouridine synthase activity
HWQ15_RS16935	COG0538	isocitrate dehydrogenase activity
HWQ15_RS16945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HWQ15_RS16955	COG2261	transglycosylase associated protein
HWQ15_RS16970	COG2203	Gaf domain
HWQ15_RS16970	COG2199	diguanylate cyclase activity
HWQ15_RS16975	COG3042	response to heat
HWQ15_RS16985	COG3189	MarR family transcriptional regulator
HWQ15_RS16990	COG0504	CTP synthase activity
HWQ15_RS16995	COG2807	transmembrane transport
HWQ15_RS17000	COG2207	Transcriptional regulator
HWQ15_RS17005	COG2707	UPF0756 membrane protein
HWQ15_RS17015	COG2211	Major facilitator Superfamily
HWQ15_RS17020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HWQ15_RS17025	COG2718	Belongs to the UPF0229 family
HWQ15_RS17030	COG2766	serine protein kinase
HWQ15_RS17035	COG3713	MltA-interacting MipA family protein
HWQ15_RS17055	COG3139	Protein of unknown function (DUF1315)
HWQ15_RS17065	COG1335	isochorismatase
HWQ15_RS17070	COG0252	asparaginase activity
HWQ15_RS17075	COG0616	signal peptide processing
HWQ15_RS17080	COG0778	Nitroreductase
HWQ15_RS17085	COG0709	Synthesizes selenophosphate from selenide and ATP
HWQ15_RS17090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HWQ15_RS17105	COG0494	nUDIX hydrolase
HWQ15_RS17110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HWQ15_RS17115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HWQ15_RS17120	COG2897	thiosulfate sulfurtransferase activity
HWQ15_RS17125	COG4136	ATPase activity
HWQ15_RS17130	COG4135	transport system, permease component
HWQ15_RS17135	COG4134	Bacterial extracellular solute-binding protein
HWQ15_RS17155	COG3138	arginine N-succinyltransferase
HWQ15_RS17160	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS17165	COG3724	N-succinylarginine dihydrolase activity
HWQ15_RS17175	COG3678	ATP-independent chaperone mediated protein folding
HWQ15_RS17185	COG0322	excinuclease ABC activity
HWQ15_RS17190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HWQ15_RS17195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HWQ15_RS17200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS17205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HWQ15_RS17210	COG1447	Phosphotransferase system cellobiose-specific component IIA
HWQ15_RS17215	COG2169	Transcriptional regulator
HWQ15_RS17215	COG1917	Cupin 2, conserved barrel domain protein
HWQ15_RS17220	COG1486	melibiose metabolic process
HWQ15_RS17225	COG3394	polysaccharide catabolic process
HWQ15_RS17230	COG0753	catalase activity
HWQ15_RS17245	COG1988	membrane-bound metal-dependent
HWQ15_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS17255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HWQ15_RS17265	COG3001	Fructosamine kinase
HWQ15_RS17275	COG1105	Belongs to the carbohydrate kinase PfkB family
HWQ15_RS17285	COG3137	Salt-induced outer membrane protein
HWQ15_RS17330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HWQ15_RS17335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HWQ15_RS17335	COG0072	phenylalanine-tRNA ligase activity
HWQ15_RS17340	COG0776	regulation of translation
HWQ15_RS17350	COG0386	Belongs to the glutathione peroxidase family
HWQ15_RS17360	COG0791	NLP P60 protein
HWQ15_RS17370	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HWQ15_RS17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HWQ15_RS17385	COG4558	Periplasmic binding protein
HWQ15_RS17390	COG3720	iron ion transport
HWQ15_RS17400	COG4256	Hemin uptake protein
HWQ15_RS17405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HWQ15_RS17410	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HWQ15_RS17415	COG0574	Belongs to the PEP-utilizing enzyme family
HWQ15_RS17415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HWQ15_RS17420	COG2211	Major facilitator Superfamily
HWQ15_RS17425	COG1472	Belongs to the glycosyl hydrolase 3 family
HWQ15_RS17440	COG0628	permease
HWQ15_RS17445	COG0277	FAD linked oxidase domain protein
HWQ15_RS17445	COG0247	lactate metabolic process
HWQ15_RS17450	COG2050	protein possibly involved in aromatic compounds catabolism
HWQ15_RS17460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HWQ15_RS17475	COG3121	Chaperone
HWQ15_RS17500	COG3383	formate dehydrogenase (NAD+) activity
HWQ15_RS17515	COG2200	EAL domain
HWQ15_RS17520	COG0789	Transcriptional regulator
HWQ15_RS17525	COG0316	Belongs to the HesB IscA family
HWQ15_RS17530	COG0719	Fe-S assembly protein
HWQ15_RS17535	COG0396	ATPase activity
HWQ15_RS17540	COG0719	Fe-S assembly protein
HWQ15_RS17545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HWQ15_RS17550	COG2166	iron-sulfur cluster assembly
HWQ15_RS17555	COG1376	ErfK ybiS ycfS ynhG family protein
HWQ15_RS17570	COG0626	cystathionine gamma-synthase activity
HWQ15_RS17585	COG2011	ABC-type metal ion transport system permease component
HWQ15_RS17590	COG1464	Belongs to the NlpA lipoprotein family
HWQ15_RS17615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HWQ15_RS17625	COG4529	Protein conserved in bacteria
HWQ15_RS17675	COG3501	Rhs element vgr protein
HWQ15_RS17685	COG0515	serine threonine protein kinase
HWQ15_RS17685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HWQ15_RS17750	COG0071	Belongs to the small heat shock protein (HSP20) family
HWQ15_RS17765	COG0534	Mate efflux family protein
HWQ15_RS17770	COG0307	riboflavin synthase, alpha
HWQ15_RS17775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HWQ15_RS17780	COG2814	Major facilitator Superfamily
HWQ15_RS17785	COG0583	DNA-binding transcription factor activity
HWQ15_RS17800	COG2814	Major facilitator Superfamily
HWQ15_RS17810	COG0791	NLP P60 protein
HWQ15_RS17815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HWQ15_RS17825	COG0346	lactoylglutathione lyase activity
HWQ15_RS17830	COG1902	pentaerythritol trinitrate reductase activity
HWQ15_RS17835	COG1309	transcriptional regulator
HWQ15_RS17840	COG2194	sulfuric ester hydrolase activity
HWQ15_RS17845	COG3313	Fe-S protein
HWQ15_RS17850	COG4989	oxidoreductase activity
HWQ15_RS17855	COG2032	superoxide dismutase activity
HWQ15_RS17860	COG1289	transmembrane transporter activity
HWQ15_RS17865	COG1566	PFAM secretion protein HlyD family protein
HWQ15_RS17880	COG3706	GGDEF domain
HWQ15_RS17890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HWQ15_RS17895	COG3895	Periplasmic Protein
HWQ15_RS17900	COG0259	pyridoxamine-phosphate oxidase activity
HWQ15_RS17905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HWQ15_RS17910	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HWQ15_RS17915	COG0625	glutathione transferase activity
HWQ15_RS17920	COG3104	oligopeptide transport
HWQ15_RS17925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HWQ15_RS17975	COG0673	inositol 2-dehydrogenase activity
HWQ15_RS17980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HWQ15_RS17985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HWQ15_RS17995	COG0582	viral genome integration into host DNA
HWQ15_RS18120	COG0305	Participates in initiation and elongation during chromosome replication
HWQ15_RS18230	COG5410	chromosome segregation
HWQ15_RS18390	COG1609	Transcriptional regulator
HWQ15_RS18395	COG5339	Protein conserved in bacteria
HWQ15_RS18405	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HWQ15_RS18405	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HWQ15_RS18420	COG2205	protein histidine kinase activity
HWQ15_RS18430	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS18435	COG3136	membrane protein required for alginate biosynthesis
HWQ15_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS18445	COG0531	amino acid
HWQ15_RS18455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HWQ15_RS18460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HWQ15_RS18465	COG0668	transmembrane transport
HWQ15_RS18470	COG0589	response to stress
HWQ15_RS18480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HWQ15_RS18485	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HWQ15_RS18490	COG1473	amidohydrolase
HWQ15_RS18500	COG0583	DNA-binding transcription factor activity
HWQ15_RS18505	COG2840	Smr protein MutS2
HWQ15_RS18515	COG0667	Aldo Keto reductase
HWQ15_RS18525	COG4993	Dehydrogenase
HWQ15_RS18570	COG1403	HNH endonuclease
HWQ15_RS18575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS18585	COG0628	permease
HWQ15_RS18590	COG2076	Multidrug Resistance protein
HWQ15_RS18595	COG2076	Multidrug Resistance protein
HWQ15_RS18600	COG3591	Belongs to the peptidase S1B family
HWQ15_RS18610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HWQ15_RS18615	COG2814	Major facilitator Superfamily
HWQ15_RS18620	COG0583	DNA-binding transcription factor activity
HWQ15_RS18625	COG1940	carbohydrate kinase activity
HWQ15_RS18630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HWQ15_RS18680	COG3141	response to X-ray
HWQ15_RS18690	COG3302	dmso reductase anchor subunit
HWQ15_RS18695	COG0437	4 iron, 4 sulfur cluster binding
HWQ15_RS18700	COG0243	molybdopterin cofactor binding
HWQ15_RS18720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS18735	COG4948	Mandelate Racemase Muconate Lactonizing
HWQ15_RS18740	COG1063	alcohol dehydrogenase
HWQ15_RS18745	COG0477	Major facilitator Superfamily
HWQ15_RS18750	COG0246	Mannitol dehydrogenase
HWQ15_RS18765	COG1802	Transcriptional regulator
HWQ15_RS18770	COG4221	oxidoreductase activity
HWQ15_RS18785	COG1278	Cold shock
HWQ15_RS18790	COG2135	peptidase activity
HWQ15_RS18825	COG0598	Magnesium transport protein CorA
HWQ15_RS18840	COG4993	Dehydrogenase
HWQ15_RS18865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HWQ15_RS18870	COG2911	Protein conserved in bacteria
HWQ15_RS18880	COG3784	Protein of unknown function (DUF1318)
HWQ15_RS18885	COG2207	Transcriptional regulator
HWQ15_RS18890	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS18895	COG3706	GGDEF domain
HWQ15_RS18895	COG2203	Gaf domain
HWQ15_RS18895	COG5001	Diguanylate cyclase
HWQ15_RS18895	COG4251	negative regulation of phosphorylation
HWQ15_RS18900	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HWQ15_RS18905	COG3733	amine oxidase
HWQ15_RS18925	COG2030	dehydratase
HWQ15_RS18925	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS18930	COG3396	Phenylacetate-CoA oxygenase
HWQ15_RS18935	COG3460	Phenylacetate-CoA oxygenase
HWQ15_RS18940	COG3396	Phenylacetate-CoA oxygenase
HWQ15_RS18945	COG2151	metal-sulfur cluster biosynthetic enzyme
HWQ15_RS18950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HWQ15_RS18955	COG1024	Enoyl-CoA hydratase
HWQ15_RS18960	COG1024	Enoyl-CoA hydratase
HWQ15_RS18965	COG1250	3-hydroxyacyl-CoA dehydrogenase
HWQ15_RS18970	COG2050	protein possibly involved in aromatic compounds catabolism
HWQ15_RS18975	COG0183	Belongs to the thiolase family
HWQ15_RS18980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HWQ15_RS18985	COG3327	negative regulation of DNA-templated transcription, initiation
HWQ15_RS18990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HWQ15_RS18995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HWQ15_RS19005	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HWQ15_RS19025	COG0300	oxidoreductase activity
HWQ15_RS19040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HWQ15_RS19070	COG0583	DNA-binding transcription factor activity
HWQ15_RS19085	COG3122	Protein conserved in bacteria
HWQ15_RS19090	COG0564	pseudouridine synthase activity
HWQ15_RS19100	COG1643	Atp-dependent helicase
HWQ15_RS19105	COG4122	O-methyltransferase activity
HWQ15_RS19110	COG1538	Outer membrane efflux protein
HWQ15_RS19125	COG0477	Major facilitator Superfamily
HWQ15_RS19130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HWQ15_RS19135	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS19140	COG3038	cytochrome b561
HWQ15_RS19145	COG0673	inositol 2-dehydrogenase activity
HWQ15_RS19150	COG1349	DNA-binding transcription factor activity
HWQ15_RS19165	COG2274	protein secretion by the type I secretion system
HWQ15_RS19220	COG0840	transmembrane signaling receptor activity
HWQ15_RS19225	COG0583	DNA-binding transcription factor activity
HWQ15_RS19230	COG5383	Protein conserved in bacteria
HWQ15_RS19235	COG2272	Belongs to the type-B carboxylesterase lipase family
HWQ15_RS19245	COG0436	Aminotransferase
HWQ15_RS19255	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HWQ15_RS19260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HWQ15_RS19265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HWQ15_RS19270	COG1275	C4-dicarboxylate transporter malic acid transport protein
HWQ15_RS19275	COG0500	methyltransferase
HWQ15_RS19280	COG2195	Cleaves the N-terminal amino acid of tripeptides
HWQ15_RS19285	COG0747	negative chemotaxis
HWQ15_RS19305	COG3135	benzoate transporter
HWQ15_RS19310	COG1396	sequence-specific DNA binding
HWQ15_RS19315	COG0826	peptidase U32
HWQ15_RS19330	COG4977	sequence-specific DNA binding
HWQ15_RS19340	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HWQ15_RS19360	COG1122	ATPase activity
HWQ15_RS19370	COG3443	Belongs to the bacterial solute-binding protein 9 family
HWQ15_RS19375	COG2814	Major facilitator Superfamily
HWQ15_RS19380	COG0697	spore germination
HWQ15_RS19395	COG1846	Transcriptional regulator
HWQ15_RS19405	COG2814	Major facilitator Superfamily
HWQ15_RS19425	COG0583	DNA-binding transcription factor activity
HWQ15_RS19430	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS19440	COG2066	Belongs to the glutaminase family
HWQ15_RS19450	COG3706	GGDEF domain
HWQ15_RS19465	COG3781	membrane
HWQ15_RS19495	COG0596	Alpha beta hydrolase
HWQ15_RS19500	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS19505	COG2205	protein histidine kinase activity
HWQ15_RS19520	COG0494	nUDIX hydrolase
HWQ15_RS19525	COG1349	DNA-binding transcription factor activity
HWQ15_RS19585	COG2814	Major facilitator Superfamily
HWQ15_RS19625	COG3121	Chaperone
HWQ15_RS19670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HWQ15_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS19695	COG0583	DNA-binding transcription factor activity
HWQ15_RS19700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HWQ15_RS19705	COG4628	conserved protein (DUF2132)
HWQ15_RS19715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HWQ15_RS19730	COG0840	transmembrane signaling receptor activity
HWQ15_RS19760	COG2200	EAL domain
HWQ15_RS19775	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HWQ15_RS19780	COG0747	negative chemotaxis
HWQ15_RS19785	COG0601	transmembrane transport
HWQ15_RS19790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HWQ15_RS19795	COG0444	Belongs to the ABC transporter superfamily
HWQ15_RS19800	COG4608	Belongs to the ABC transporter superfamily
HWQ15_RS19805	COG1764	response to oxidative stress
HWQ15_RS19835	COG0281	malic enzyme
HWQ15_RS19850	COG0488	(ABC) transporter
HWQ15_RS19855	COG1064	alcohol dehydrogenase
HWQ15_RS19865	COG1252	NADH dehydrogenase
HWQ15_RS19870	COG2814	Major facilitator Superfamily
HWQ15_RS19880	COG2864	formate dehydrogenase
HWQ15_RS19885	COG0437	4 iron, 4 sulfur cluster binding
HWQ15_RS19895	COG0697	spore germination
HWQ15_RS19915	COG2223	nitrite transmembrane transporter activity
HWQ15_RS19920	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HWQ15_RS19925	COG1140	nitrate reductase beta subunit
HWQ15_RS19930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HWQ15_RS19935	COG2181	nitrate reductase activity
HWQ15_RS19940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HWQ15_RS19945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HWQ15_RS19950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HWQ15_RS19955	COG0640	Transcriptional regulator
HWQ15_RS19960	COG0583	DNA-binding transcription factor activity
HWQ15_RS19965	COG0456	acetyltransferase
HWQ15_RS19975	COG1560	Kdo2-lipid A biosynthetic process
HWQ15_RS19980	COG1942	4-Oxalocrotonate Tautomerase
HWQ15_RS19985	COG0625	glutathione transferase activity
HWQ15_RS19990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HWQ15_RS19995	COG1126	abc transporter atp-binding protein
HWQ15_RS20015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS20020	COG1473	amidohydrolase
HWQ15_RS20025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HWQ15_RS20050	COG4772	TonB-dependent receptor
HWQ15_RS20055	COG1802	Transcriptional regulator
HWQ15_RS20060	COG2130	NADP-dependent
HWQ15_RS20070	COG1247	-acetyltransferase
HWQ15_RS20075	COG3238	Protein conserved in bacteria
HWQ15_RS20085	COG0747	negative chemotaxis
HWQ15_RS20115	COG3615	Tellurite resistance protein tehB
HWQ15_RS20120	COG3615	Tellurite resistance protein tehB
HWQ15_RS20130	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS20135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HWQ15_RS20145	COG1271	oxidase subunit
HWQ15_RS20150	COG1294	oxidase, subunit
HWQ15_RS20160	COG3187	Heat shock protein
HWQ15_RS20165	COG3042	response to heat
HWQ15_RS20170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HWQ15_RS20170	COG0674	pyruvate-flavodoxin oxidoreductase activity
HWQ15_RS20170	COG1013	pyruvate-flavodoxin oxidoreductase activity
HWQ15_RS20170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HWQ15_RS20175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HWQ15_RS20190	COG2135	peptidase activity
HWQ15_RS20200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HWQ15_RS20340	COG5484	DNA packaging
HWQ15_RS20340	COG3728	DNA packaging
HWQ15_RS20380	COG3772	lysozyme
HWQ15_RS20390	COG0484	heat shock protein binding
HWQ15_RS20395	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HWQ15_RS20440	COG1846	Transcriptional regulator
HWQ15_RS20490	COG0582	viral genome integration into host DNA
HWQ15_RS20500	COG0513	Belongs to the DEAD box helicase family
HWQ15_RS20515	COG0840	transmembrane signaling receptor activity
HWQ15_RS20630	COG4166	transmembrane transport
HWQ15_RS20635	COG2866	Carboxypeptidase
HWQ15_RS20640	COG4948	Mandelate Racemase Muconate Lactonizing
HWQ15_RS20645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HWQ15_RS20655	COG3768	UPF0283 membrane protein
HWQ15_RS20660	COG3106	COG3106 Predicted ATPase
HWQ15_RS20665	COG1609	Transcriptional regulator
HWQ15_RS20675	COG3842	ATPase activity
HWQ15_RS20680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HWQ15_RS20685	COG1554	hydrolase, family 65, central catalytic
HWQ15_RS20690	COG0673	inositol 2-dehydrogenase activity
HWQ15_RS20695	COG1082	Xylose isomerase domain protein TIM barrel
HWQ15_RS20700	COG1063	alcohol dehydrogenase
HWQ15_RS20705	COG0395	ABC-type sugar transport system, permease component
HWQ15_RS20710	COG1175	transmembrane transport
HWQ15_RS20715	COG1653	transport
HWQ15_RS20720	COG0366	Alpha amylase catalytic
HWQ15_RS20730	COG1983	PspC domain protein
HWQ15_RS20740	COG1842	Phage shock protein A
HWQ15_RS20745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HWQ15_RS20760	COG4171	peptide transport system, permease
HWQ15_RS20770	COG4172	Belongs to the ABC transporter superfamily
HWQ15_RS20775	COG1309	transcriptional regulator
HWQ15_RS20780	COG0251	oxidation-reduction process
HWQ15_RS20785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HWQ15_RS20790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HWQ15_RS20790	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HWQ15_RS20795	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HWQ15_RS20800	COG5001	Diguanylate cyclase
HWQ15_RS20805	COG1024	Enoyl-CoA hydratase
HWQ15_RS20815	COG1349	DNA-binding transcription factor activity
HWQ15_RS20825	COG0023	Translation Initiation Factor
HWQ15_RS20830	COG0284	orotidine-5'-phosphate decarboxylase activity
HWQ15_RS20835	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HWQ15_RS20840	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HWQ15_RS20845	COG0671	phosphoesterase, PA-phosphatase related
HWQ15_RS20855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HWQ15_RS20885	COG0616	signal peptide processing
HWQ15_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
HWQ15_RS20895	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HWQ15_RS20905	COG0009	L-threonylcarbamoyladenylate synthase
HWQ15_RS20910	COG0613	PHP domain protein
HWQ15_RS20920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HWQ15_RS20925	COG0512	Glutamine amidotransferase of anthranilate synthase
HWQ15_RS20925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HWQ15_RS20935	COG0133	tryptophan synthase activity
HWQ15_RS20940	COG0159	tryptophan synthase activity
HWQ15_RS20945	COG2391	methyltransferase activity
HWQ15_RS20950	COG0425	Belongs to the sulfur carrier protein TusA family
HWQ15_RS20955	COG3047	cAMP biosynthetic process
HWQ15_RS20960	COG0727	PFAM Uncharacterised protein family (UPF0153)
HWQ15_RS20990	COG2350	Protein conserved in bacteria
HWQ15_RS20995	COG1280	lysine exporter protein (LysE YggA)
HWQ15_RS21015	COG3099	Belongs to the UPF0263 family
HWQ15_RS21020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HWQ15_RS21025	COG4608	Belongs to the ABC transporter superfamily
HWQ15_RS21030	COG0444	Belongs to the ABC transporter superfamily
HWQ15_RS21050	COG2095	MarC family integral membrane protein
HWQ15_RS21055	COG1012	belongs to the aldehyde dehydrogenase family
HWQ15_RS21055	COG1454	alcohol dehydrogenase
HWQ15_RS21060	COG1435	thymidine kinase activity
HWQ15_RS21070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HWQ15_RS21075	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS21080	COG1752	Esterase of the alpha-beta hydrolase superfamily
HWQ15_RS21085	COG3012	SEC-C Motif Domain Protein
HWQ15_RS21090	COG0788	formyltetrahydrofolate deformylase activity
HWQ15_RS21105	COG2181	nitrate reductase activity
HWQ15_RS21110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HWQ15_RS21115	COG1140	nitrate reductase beta subunit
HWQ15_RS21120	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HWQ15_RS21125	COG2223	nitrite transmembrane transporter activity
HWQ15_RS21130	COG3850	Histidine kinase
HWQ15_RS21135	COG2197	response regulator
HWQ15_RS21140	COG4932	domain protein
HWQ15_RS21145	COG0243	molybdopterin cofactor binding
HWQ15_RS21150	COG2146	nitrite reductase [NAD(P)H] activity
HWQ15_RS21150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HWQ15_RS21155	COG1116	anion transmembrane transporter activity
HWQ15_RS21165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HWQ15_RS21170	COG3707	response regulator
HWQ15_RS21175	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HWQ15_RS21180	COG0840	transmembrane signaling receptor activity
HWQ15_RS21190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HWQ15_RS21195	COG4572	Cation transport regulator
HWQ15_RS21200	COG0387	Pfam Sodium calcium exchanger
HWQ15_RS21205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HWQ15_RS21220	COG2890	protein-(glutamine-N5) methyltransferase activity
HWQ15_RS21230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HWQ15_RS21240	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HWQ15_RS21250	COG0659	secondary active sulfate transmembrane transporter activity
HWQ15_RS21265	COG0193	aminoacyl-tRNA hydrolase activity
HWQ15_RS21270	COG0012	GTP binding
HWQ15_RS21285	COG3209	COG3209 Rhs family protein
HWQ15_RS21300	COG3501	Rhs element vgr protein
HWQ15_RS21320	COG0515	serine threonine protein kinase
HWQ15_RS21440	COG4977	sequence-specific DNA binding
HWQ15_RS21445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HWQ15_RS21455	COG4774	siderophore transport
HWQ15_RS21465	COG0741	lytic transglycosylase activity
HWQ15_RS21470	COG1619	proteins homologs of microcin C7 resistance protein MccF
HWQ15_RS21475	COG3263	regulation of cellular component size
HWQ15_RS21480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HWQ15_RS21485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HWQ15_RS21490	COG2719	SpoVR family
HWQ15_RS21500	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HWQ15_RS21510	COG2983	Belongs to the UPF0260 family
HWQ15_RS21515	COG0179	Fumarylacetoacetate (FAA) hydrolase
HWQ15_RS21525	COG0850	regulation of cytokinetic process
HWQ15_RS21530	COG2894	cell division
HWQ15_RS21535	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HWQ15_RS21540	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HWQ15_RS21545	COG0318	PFAM AMP-dependent synthetase and ligase
HWQ15_RS21550	COG3065	identical protein binding
HWQ15_RS21555	COG1214	PFAM Peptidase M22, glycoprotease
HWQ15_RS21560	COG1199	ATP-dependent helicase activity
HWQ15_RS21565	COG0251	oxidation-reduction process
HWQ15_RS21570	COG3140	Belongs to the UPF0181 family
HWQ15_RS21585	COG1760	l-serine dehydratase
HWQ15_RS21590	COG2200	EAL domain
HWQ15_RS21595	COG1253	flavin adenine dinucleotide binding
HWQ15_RS21600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HWQ15_RS21600	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HWQ15_RS21605	COG3715	PTS system
HWQ15_RS21610	COG3716	PTS system mannose fructose sorbose family IID component
HWQ15_RS21615	COG4811	Protein of unknown function (DUF986)
HWQ15_RS21620	COG1971	Probably functions as a manganese efflux pump
HWQ15_RS21625	COG2226	methyltransferase
HWQ15_RS21630	COG0768	penicillin binding
HWQ15_RS21660	COG1414	Transcriptional regulator
HWQ15_RS21665	COG2814	Major facilitator Superfamily
HWQ15_RS21670	COG0501	Belongs to the peptidase M48B family
HWQ15_RS21680	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HWQ15_RS21685	COG1956	GAF domain-containing protein
HWQ15_RS21690	COG2995	paraquat-inducible protein a
HWQ15_RS21695	COG3008	intermembrane lipid transfer
HWQ15_RS21700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HWQ15_RS21700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HWQ15_RS21715	COG2990	Protein conserved in bacteria
HWQ15_RS21730	COG1276	copper resistance
HWQ15_RS21735	COG2372	response to copper ion
HWQ15_RS21745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HWQ15_RS21750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HWQ15_RS21755	COG1770	oligopeptidase
HWQ15_RS21760	COG2979	Protein of unknown function (DUF533)
HWQ15_RS21800	COG0800	Aldolase
HWQ15_RS21805	COG0129	dihydroxy-acid dehydratase activity
HWQ15_RS21810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HWQ15_RS21815	COG1737	Transcriptional regulator
HWQ15_RS21825	COG1560	Kdo2-lipid A biosynthetic process
HWQ15_RS21830	COG0739	heme binding
HWQ15_RS21835	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HWQ15_RS21845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HWQ15_RS21850	COG2255	four-way junction helicase activity
HWQ15_RS21855	COG0632	four-way junction helicase activity
HWQ15_RS21870	COG0494	nUDIX hydrolase
HWQ15_RS21880	COG1335	isochorismatase
HWQ15_RS21885	COG1801	Protein of unknown function DUF72
HWQ15_RS21890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HWQ15_RS21895	COG2226	methyltransferase
HWQ15_RS21900	COG0500	methyltransferase
HWQ15_RS21905	COG3142	Participates in the control of copper homeostasis
HWQ15_RS21910	COG3102	Protein conserved in bacteria
HWQ15_RS21915	COG0018	arginyl-trna synthetase
HWQ15_RS21930	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HWQ15_RS21960	COG0745	RESPONSE REGULATOR receiver
HWQ15_RS21975	COG0840	transmembrane signaling receptor activity
HWQ15_RS22010	COG1301	dicarboxylic acid transport
HWQ15_RS22050	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HWQ15_RS22060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HWQ15_RS22070	COG1879	ABC-type sugar transport system periplasmic component
HWQ15_RS22080	COG1528	Iron-storage protein
HWQ15_RS22085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HWQ15_RS22115	COG1528	Iron-storage protein
HWQ15_RS22125	COG0814	amino acid
HWQ15_RS22130	COG3012	SEC-C Motif Domain Protein
HWQ15_RS22130	COG3318	Belongs to the UPF0149 family
HWQ15_RS22165	COG0583	DNA-binding transcription factor activity
HWQ15_RS22195	COG2197	response regulator
HWQ15_RS22205	COG2197	response regulator
HWQ15_RS22240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HWQ15_RS22245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HWQ15_RS22250	COG1516	flagellar protein fliS
HWQ15_RS22260	COG0366	Alpha amylase catalytic
HWQ15_RS22270	COG1677	Flagellar hook-basal body complex protein FliE
HWQ15_RS22280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HWQ15_RS22290	COG1157	protein secretion by the type III secretion system
HWQ15_RS22330	COG1987	bacterial-type flagellum assembly
HWQ15_RS22340	COG2197	response regulator
HWQ15_RS22365	COG5475	Uncharacterized small protein (DUF2158)
HWQ15_RS22370	COG2354	Protein conserved in bacteria
HWQ15_RS22375	COG0697	spore germination
HWQ15_RS22380	COG3727	T/G mismatch-specific endonuclease activity
HWQ15_RS22385	COG0270	DNA (cytosine-5-)-methyltransferase activity
HWQ15_RS22390	COG1418	mRNA catabolic process
HWQ15_RS22395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HWQ15_RS22405	COG3290	protein histidine kinase activity
HWQ15_RS22410	COG4565	transcriptional regulatory protein
HWQ15_RS22430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HWQ15_RS22430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HWQ15_RS22455	COG0583	DNA-binding transcription factor activity
HWQ15_RS22515	COG1376	ErfK ybiS ycfS ynhG family protein
HWQ15_RS22520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HWQ15_RS22525	COG0589	response to stress
HWQ15_RS22535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HWQ15_RS22550	COG0477	Major facilitator Superfamily
HWQ15_RS22555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HWQ15_RS22560	COG0006	proline dipeptidase activity
HWQ15_RS22570	COG0534	Mate efflux family protein
HWQ15_RS22585	COG1289	transmembrane transporter activity
HWQ15_RS22590	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HWQ15_RS22600	COG2925	Exonuclease
HWQ15_RS22755	COG5410	chromosome segregation
HWQ15_RS22920	COG3723	Recombinational DNA repair protein, rece pathway
HWQ15_RS22980	COG0531	amino acid
HWQ15_RS22990	COG0583	DNA-binding transcription factor activity
HWQ15_RS22995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HWQ15_RS23005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HWQ15_RS23015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HWQ15_RS23020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HWQ15_RS23020	COG0131	Imidazoleglycerol-phosphate dehydratase
HWQ15_RS23025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HWQ15_RS23030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HWQ15_RS23035	COG0107	imidazoleglycerol-phosphate synthase activity
HWQ15_RS23040	COG0140	phosphoribosyl-ATP diphosphatase activity
HWQ15_RS23040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HWQ15_RS23060	COG0110	maltose O-acetyltransferase activity
HWQ15_RS23070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH