locus-tag	class	description
HV340_RS00010	COG0592	DNA-directed DNA polymerase activity
HV340_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV340_RS00025	COG0583	DNA-binding transcription factor activity
HV340_RS00035	COG0561	phosphatase activity
HV340_RS00040	COG2186	Transcriptional regulator
HV340_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HV340_RS00050	COG0800	Aldolase
HV340_RS00055	COG4948	Mandelate Racemase Muconate Lactonizing
HV340_RS00060	COG2271	Major facilitator Superfamily
HV340_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
HV340_RS00070	COG5645	(Lipo)protein
HV340_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
HV340_RS00085	COG2985	domain, Protein
HV340_RS00090	COG2188	Transcriptional regulator
HV340_RS00105	COG2149	membrane
HV340_RS00120	COG2610	gluconate transmembrane transporter activity
HV340_RS00125	COG0583	DNA-binding transcription factor activity
HV340_RS00135	COG2814	Major facilitator Superfamily
HV340_RS00160	COG0028	Belongs to the TPP enzyme family
HV340_RS00165	COG0440	acetolactate synthase activity
HV340_RS00170	COG2197	response regulator
HV340_RS00190	COG0596	Alpha beta hydrolase
HV340_RS00200	COG0583	DNA-binding transcription factor activity
HV340_RS00210	COG2814	Major facilitator Superfamily
HV340_RS00220	COG0183	Belongs to the thiolase family
HV340_RS00230	COG0667	Aldo Keto reductase
HV340_RS00240	COG0697	spore germination
HV340_RS00245	COG4580	involved in the transport of maltose and maltodextrins
HV340_RS00250	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV340_RS00255	COG2723	6-phospho-beta-galactosidase activity
HV340_RS00260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS00260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS00270	COG1609	Transcriptional regulator
HV340_RS00290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS00300	COG0454	-acetyltransferase
HV340_RS00305	COG1309	transcriptional regulator
HV340_RS00315	COG1464	Belongs to the NlpA lipoprotein family
HV340_RS00335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV340_RS00345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV340_RS00350	COG3272	Protein of unknown function (DUF1722)
HV340_RS00355	COG2351	hydroxyisourate hydrolase activity
HV340_RS00360	COG0789	Transcriptional regulator
HV340_RS00380	COG0519	Catalyzes the synthesis of GMP from XMP
HV340_RS00400	COG2003	Belongs to the UPF0758 family
HV340_RS00495	COG0582	viral genome integration into host DNA
HV340_RS00505	COG2211	Major facilitator Superfamily
HV340_RS00510	COG1501	Belongs to the glycosyl hydrolase 31 family
HV340_RS00515	COG2982	Protein involved in outer membrane biogenesis
HV340_RS00520	COG2233	PERMEase
HV340_RS00525	COG0786	glutamate:sodium symporter activity
HV340_RS00530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV340_RS00535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV340_RS00540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV340_RS00560	COG2860	membrane
HV340_RS00565	COG1561	YicC-like family, N-terminal region
HV340_RS00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HV340_RS00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV340_RS00595	COG2003	Belongs to the UPF0758 family
HV340_RS00600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HV340_RS00605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV340_RS00610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HV340_RS00615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HV340_RS00625	COG1519	Transferase
HV340_RS00630	COG1216	Glycosyl transferase, family 2
HV340_RS00635	COG0438	transferase activity, transferring glycosyl groups
HV340_RS00640	COG0438	transferase activity, transferring glycosyl groups
HV340_RS00645	COG0859	PFAM glycosyl transferase family 9
HV340_RS00660	COG1215	transferase activity, transferring glycosyl groups
HV340_RS00670	COG0859	PFAM glycosyl transferase family 9
HV340_RS00675	COG0859	PFAM glycosyl transferase family 9
HV340_RS00690	COG1063	alcohol dehydrogenase
HV340_RS00695	COG0859	PFAM glycosyl transferase family 9
HV340_RS00700	COG0463	Glycosyl transferase, family 2
HV340_RS00705	COG2861	carbohydrate metabolic process
HV340_RS00710	COG4942	peptidase
HV340_RS00715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HV340_RS00720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV340_RS00725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV340_RS00730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HV340_RS00735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HV340_RS00745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV340_RS00750	COG2271	Major facilitator Superfamily
HV340_RS00760	COG2186	Transcriptional regulator
HV340_RS00775	COG3722	fumarate hydratase activity
HV340_RS00785	COG2213	PTS system mannitol-specific
HV340_RS00785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS00795	COG1566	PFAM secretion protein HlyD family protein
HV340_RS00800	COG0625	glutathione transferase activity
HV340_RS00810	COG3276	selenocysteine insertion sequence binding
HV340_RS00815	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS00820	COG0583	DNA-binding transcription factor activity
HV340_RS00825	COG3713	MltA-interacting MipA family protein
HV340_RS00835	COG2211	Major facilitator Superfamily
HV340_RS00845	COG0235	Class ii aldolase
HV340_RS00850	COG3623	hexulose-6-phosphate isomerase
HV340_RS00855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV340_RS00860	COG1070	Carbohydrate kinase
HV340_RS00875	COG2731	YhcH YjgK YiaL family protein
HV340_RS00885	COG1414	Transcriptional regulator
HV340_RS00890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV340_RS00895	COG3977	Valine--pyruvate aminotransferase
HV340_RS00900	COG0366	Alpha amylase catalytic
HV340_RS00905	COG2992	FlgJ-related protein
HV340_RS00910	COG1609	Transcriptional regulator
HV340_RS00910	COG2207	Transcriptional regulator
HV340_RS00915	COG4214	carbohydrate transport
HV340_RS00925	COG4213	ABC transporter substrate-binding protein
HV340_RS00930	COG2115	Belongs to the xylose isomerase family
HV340_RS00935	COG1070	Carbohydrate kinase
HV340_RS00940	COG1335	isochorismatase
HV340_RS00950	COG3274	enterobacterial common antigen metabolic process
HV340_RS00960	COG0752	glycyl-tRNA synthetase alpha subunit
HV340_RS00965	COG0751	glycine-tRNA ligase activity
HV340_RS00970	COG0488	(ABC) transporter
HV340_RS00975	COG2944	sequence-specific DNA binding
HV340_RS00985	COG1278	Cold shock
HV340_RS00990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV340_RS01000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV340_RS01010	COG1609	Transcriptional regulator
HV340_RS01015	COG2885	chlorophyll binding
HV340_RS01020	COG0243	molybdopterin cofactor binding
HV340_RS01025	COG0456	acetyltransferase
HV340_RS01030	COG2818	Glycosylase
HV340_RS01035	COG5571	outer membrane autotransporter
HV340_RS01040	COG2223	nitrite transmembrane transporter activity
HV340_RS01045	COG2194	sulfuric ester hydrolase activity
HV340_RS01055	COG0747	negative chemotaxis
HV340_RS01060	COG0601	transmembrane transport
HV340_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV340_RS01070	COG0444	Belongs to the ABC transporter superfamily
HV340_RS01075	COG4608	Belongs to the ABC transporter superfamily
HV340_RS01080	COG1072	(Pantothenic acid kinase))
HV340_RS01115	COG0250	Participates in transcription elongation, termination and antitermination
HV340_RS01160	COG3706	GGDEF domain
HV340_RS01170	COG2022	thiamine diphosphate biosynthetic process
HV340_RS01175	COG2104	thiamine diphosphate biosynthetic process
HV340_RS01180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV340_RS01195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HV340_RS01205	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HV340_RS01215	COG3068	Protein conserved in bacteria
HV340_RS01260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV340_RS01270	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HV340_RS01290	COG1187	pseudouridine synthase activity
HV340_RS01305	COG0527	aspartate kinase activity
HV340_RS01330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV340_RS01335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV340_RS01345	COG3223	Belongs to the PsiE family
HV340_RS01350	COG3833	ABC-type maltose transport systems, permease component
HV340_RS01370	COG4580	involved in the transport of maltose and maltodextrins
HV340_RS01380	COG3161	chorismate lyase activity
HV340_RS01390	COG2937	Belongs to the GPAT DAPAT family
HV340_RS01395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV340_RS01400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV340_RS01405	COG0534	Mate efflux family protein
HV340_RS01410	COG3237	CsbD-like
HV340_RS01415	COG0735	belongs to the Fur family
HV340_RS01430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV340_RS01440	COG0604	alcohol dehydrogenase
HV340_RS01445	COG0305	Participates in initiation and elongation during chromosome replication
HV340_RS01465	COG1448	Aminotransferase
HV340_RS01470	COG3700	Belongs to the class B bacterial acid phosphatase family
HV340_RS01475	COG0432	Pfam Uncharacterised protein family UPF0047
HV340_RS01480	COG2315	Protein conserved in bacteria
HV340_RS01490	COG0629	single-stranded DNA binding
HV340_RS01500	COG2199	diguanylate cyclase activity
HV340_RS01505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV340_RS01515	COG0789	Transcriptional regulator
HV340_RS01525	COG2252	PERMEase
HV340_RS01530	COG0025	NhaP-type Na H and K H
HV340_RS01535	COG0583	DNA-binding transcription factor activity
HV340_RS01545	COG1346	cytolysis
HV340_RS01550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV340_RS01555	COG3162	membrane
HV340_RS01560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HV340_RS01565	COG1301	dicarboxylic acid transport
HV340_RS01570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV340_RS01580	COG0745	RESPONSE REGULATOR receiver
HV340_RS01590	COG0191	fructose-bisphosphate aldolase activity
HV340_RS01605	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS01610	COG1129	ABC transporter
HV340_RS01615	COG4191	Histidine kinase
HV340_RS01615	COG0784	Response regulator, receiver
HV340_RS01625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV340_RS01630	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS01635	COG1129	ABC transporter
HV340_RS01640	COG1879	ABC-type sugar transport system periplasmic component
HV340_RS01645	COG1737	Transcriptional regulator
HV340_RS01650	COG0698	ribose 5-phosphate isomerase
HV340_RS01660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV340_RS01665	COG0456	acetyltransferase
HV340_RS01670	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV340_RS01675	COG3454	Phosphonate metabolism
HV340_RS01680	COG4778	phosphonate C-P lyase system protein PhnL
HV340_RS01685	COG4107	phosphonate C-P lyase system protein PhnK
HV340_RS01690	COG3627	carbon phosphorus lyase activity
HV340_RS01695	COG3626	phosphonate metabolism
HV340_RS01700	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV340_RS01705	COG3624	Phosphonate C-P lyase system protein PhnG
HV340_RS01710	COG2188	Transcriptional regulator
HV340_RS01715	COG3639	organic phosphonate transmembrane transporter activity
HV340_RS01720	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV340_RS01730	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV340_RS01735	COG2824	Alkylphosphonate utilization operon protein PhnA
HV340_RS01740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HV340_RS01760	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV340_RS01790	COG1309	transcriptional regulator
HV340_RS01795	COG4232	protein-disulfide reductase activity
HV340_RS01805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV340_RS01810	COG1027	Aspartate ammonia-lyase
HV340_RS01815	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV340_RS01820	COG0531	amino acid
HV340_RS01850	COG5510	response to toxic substance
HV340_RS01880	COG0583	DNA-binding transcription factor activity
HV340_RS01885	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HV340_RS01890	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
HV340_RS01895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV340_RS01900	COG1053	succinate dehydrogenase
HV340_RS01905	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HV340_RS01915	COG3264	Mechanosensitive ion channel
HV340_RS01915	COG1511	domain protein
HV340_RS01930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HV340_RS01950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV340_RS01955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV340_RS01955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV340_RS01960	COG0802	atpase or kinase
HV340_RS01970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HV340_RS01975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HV340_RS01980	COG1923	regulation of RNA biosynthetic process
HV340_RS01985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV340_RS01990	COG0330	HflC and HflK could
HV340_RS01995	COG0330	HflC and HflK could
HV340_RS02000	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV340_RS02010	COG1959	2 iron, 2 sulfur cluster binding
HV340_RS02015	COG0557	exoribonuclease II activity
HV340_RS02020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV340_RS02025	COG0477	Major facilitator Superfamily
HV340_RS02030	COG1960	acyl-CoA dehydrogenase activity
HV340_RS02045	COG3650	response to hydrogen peroxide
HV340_RS02050	COG1073	alpha beta
HV340_RS02105	COG2965	DNA replication, synthesis of RNA primer
HV340_RS02110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV340_RS02115	COG0359	binds to the 23S rRNA
HV340_RS02120	COG0697	spore germination
HV340_RS02125	COG3061	Opacity-associated protein A
HV340_RS02130	COG0545	Peptidyl-prolyl cis-trans isomerase
HV340_RS02135	COG1113	amino acid transport
HV340_RS02145	COG0840	transmembrane signaling receptor activity
HV340_RS02150	COG0697	spore germination
HV340_RS02160	COG0702	epimerase
HV340_RS02165	COG1733	regulation of RNA biosynthetic process
HV340_RS02175	COG1218	3'(2'),5'-bisphosphate nucleotidase
HV340_RS02180	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV340_RS02190	COG1253	flavin adenine dinucleotide binding
HV340_RS02195	COG2211	Major facilitator Superfamily
HV340_RS02200	COG0673	inositol 2-dehydrogenase activity
HV340_RS02210	COG0673	inositol 2-dehydrogenase activity
HV340_RS02215	COG0673	inositol 2-dehydrogenase activity
HV340_RS02220	COG1609	Transcriptional regulator
HV340_RS02225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV340_RS02230	COG0729	surface antigen
HV340_RS02235	COG2911	Protein conserved in bacteria
HV340_RS02240	COG2105	PFAM AIG2 family protein
HV340_RS02255	COG1879	ABC-type sugar transport system periplasmic component
HV340_RS02260	COG1129	ABC transporter
HV340_RS02265	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS02270	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS02280	COG0583	DNA-binding transcription factor activity
HV340_RS02290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV340_RS02295	COG3028	Belongs to the UPF0307 family
HV340_RS02300	COG0312	modulator of DNA gyrase
HV340_RS02335	COG3964	amidohydrolase
HV340_RS02355	COG3711	transcriptional antiterminator
HV340_RS02355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS02360	COG3077	Addiction module antitoxin, RelB DinJ family
HV340_RS02365	COG2026	Addiction module toxin, RelE StbE family
HV340_RS02380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV340_RS02380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV340_RS02380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS02405	COG0366	Alpha amylase catalytic
HV340_RS02410	COG1263	PTS System
HV340_RS02410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS02415	COG1609	Transcriptional regulator
HV340_RS02425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HV340_RS02430	COG0251	oxidation-reduction process
HV340_RS02440	COG0540	Belongs to the ATCase OTCase family
HV340_RS02450	COG1438	arginine binding
HV340_RS02455	COG1288	antiporter activity
HV340_RS02470	COG2235	arginine
HV340_RS02475	COG2731	YhcH YjgK YiaL family protein
HV340_RS02480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV340_RS02485	COG0129	dihydroxy-acid dehydratase activity
HV340_RS02490	COG2211	Major facilitator Superfamily
HV340_RS02495	COG3507	Belongs to the glycosyl hydrolase 43 family
HV340_RS02500	COG1414	Transcriptional regulator
HV340_RS02505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV340_RS02530	COG0582	viral genome integration into host DNA
HV340_RS02560	COG1609	Transcriptional regulator
HV340_RS02570	COG2211	Major facilitator Superfamily
HV340_RS02575	COG0346	lactoylglutathione lyase activity
HV340_RS02580	COG1349	DNA-binding transcription factor activity
HV340_RS02585	COG0740	serine-type endopeptidase activity
HV340_RS02590	COG2850	peptidyl-arginine hydroxylation
HV340_RS02615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV340_RS02635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV340_RS02640	COG0583	DNA-binding transcription factor activity
HV340_RS02645	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS02660	COG0640	Transcriptional regulator
HV340_RS02680	COG2733	membrane
HV340_RS02695	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS02715	COG0523	cobalamin synthesis protein
HV340_RS02720	COG2879	small protein
HV340_RS02725	COG1966	Carbon starvation protein
HV340_RS02735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV340_RS02740	COG2368	4-hydroxyphenylacetate
HV340_RS02760	COG3971	2-oxopent-4-enoate hydratase activity
HV340_RS02770	COG3384	dioxygenase
HV340_RS02775	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS02780	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV340_RS02785	COG1846	Transcriptional regulator
HV340_RS02790	COG0840	transmembrane signaling receptor activity
HV340_RS02825	COG1484	DNA-dependent DNA replication
HV340_RS02835	COG1764	response to oxidative stress
HV340_RS02840	COG1846	Transcriptional regulator
HV340_RS02845	COG1309	transcriptional regulator
HV340_RS02850	COG3610	response to peptide
HV340_RS02855	COG2966	Psort location CytoplasmicMembrane, score
HV340_RS02860	COG2197	response regulator
HV340_RS02865	COG2197	response regulator
HV340_RS02870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV340_RS02875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS02880	COG4114	ferric iron reductase
HV340_RS02885	COG3706	GGDEF domain
HV340_RS02910	COG2813	Specifically methylates the guanine in position
HV340_RS02915	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV340_RS02920	COG0456	acetyltransferase
HV340_RS02925	COG1011	Hydrolase
HV340_RS02935	COG2823	Periplasmic or secreted lipoprotein
HV340_RS02940	COG5487	UPF0391 membrane protein
HV340_RS02945	COG4667	esterase of the alpha-beta hydrolase superfamily
HV340_RS02950	COG0084	hydrolase, TatD family'
HV340_RS02955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV340_RS02960	COG1328	CTP reductase activity
HV340_RS02980	COG0813	purine-nucleoside phosphorylase activity
HV340_RS02985	COG3539	Fimbrial protein
HV340_RS02995	COG3188	usher protein
HV340_RS03000	COG3121	Chaperone
HV340_RS03010	COG3539	Fimbrial protein
HV340_RS03015	COG3539	Fimbrial protein
HV340_RS03025	COG3726	membrane protein affecting hemolysin expression
HV340_RS03030	COG0560	Phosphoserine phosphatase
HV340_RS03035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HV340_RS03045	COG0604	alcohol dehydrogenase
HV340_RS03055	COG0488	(ABC) transporter
HV340_RS03060	COG0741	lytic transglycosylase activity
HV340_RS03065	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
HV340_RS03070	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HV340_RS03075	COG0406	alpha-ribazole phosphatase activity
HV340_RS03080	COG2207	Transcriptional regulator
HV340_RS03080	COG3708	Transcriptional regulator
HV340_RS03085	COG3045	CreA protein
HV340_RS03090	COG0745	RESPONSE REGULATOR receiver
HV340_RS03095	COG2205	protein histidine kinase activity
HV340_RS03100	COG4452	Inner membrane protein CreD
HV340_RS03105	COG0745	RESPONSE REGULATOR receiver
HV340_RS03115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV340_RS03125	COG0460	homoserine dehydrogenase
HV340_RS03125	COG0527	aspartate kinase activity
HV340_RS03135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV340_RS03145	COG3022	response to hydroperoxide
HV340_RS03150	COG1115	amino acid carrier protein
HV340_RS03160	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV340_RS03165	COG0477	Major facilitator Superfamily
HV340_RS03170	COG1584	GPR1 FUN34 yaaH family protein
HV340_RS03185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HV340_RS03190	COG0583	DNA-binding transcription factor activity
HV340_RS03195	COG0268	Binds directly to 16S ribosomal RNA
HV340_RS03200	COG0196	riboflavin kinase activity
HV340_RS03215	COG1047	Peptidyl-prolyl cis-trans
HV340_RS03220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HV340_RS03225	COG2140	Oxalate decarboxylase
HV340_RS03235	COG3716	PTS system mannose fructose sorbose family IID component
HV340_RS03240	COG3715	PTS system
HV340_RS03245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS03260	COG1609	Transcriptional regulator
HV340_RS03270	COG0505	Belongs to the CarA family
HV340_RS03285	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV340_RS03290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV340_RS03290	COG0475	glutathione-regulated potassium exporter activity
HV340_RS03300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HV340_RS03305	COG2967	ApaG domain
HV340_RS03315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV340_RS03320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV340_RS03325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV340_RS03330	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HV340_RS03335	COG0564	pseudouridine synthase activity
HV340_RS03340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HV340_RS03345	COG0417	DNA replication proofreading
HV340_RS03350	COG0235	Class ii aldolase
HV340_RS03355	COG2160	L-arabinose isomerase activity
HV340_RS03360	COG1069	ribulokinase activity
HV340_RS03370	COG0586	Pfam SNARE associated Golgi protein
HV340_RS03380	COG1178	ABC-type Fe3 transport system permease component
HV340_RS03400	COG2814	Major facilitator Superfamily
HV340_RS03420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV340_RS03440	COG0028	Belongs to the TPP enzyme family
HV340_RS03450	COG1609	Transcriptional regulator
HV340_RS03455	COG2001	Belongs to the MraZ family
HV340_RS03470	COG0768	penicillin binding
HV340_RS03475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HV340_RS03480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV340_RS03485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV340_RS03495	COG0772	Belongs to the SEDS family
HV340_RS03505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV340_RS03510	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV340_RS03520	COG0849	cell division
HV340_RS03525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV340_RS03530	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HV340_RS03540	COG0653	protein targeting
HV340_RS03545	COG0494	nUDIX hydrolase
HV340_RS03550	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HV340_RS03555	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HV340_RS03565	COG0516	GMP reductase activity
HV340_RS03570	COG1459	type II secretion system
HV340_RS03575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV340_RS03580	COG4969	Belongs to the N-Me-Phe pilin family
HV340_RS03590	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV340_RS03595	COG3725	Membrane protein required for beta-lactamase induction
HV340_RS03600	COG3940	Belongs to the glycosyl hydrolase 43 family
HV340_RS03605	COG2211	Major facilitator Superfamily
HV340_RS03610	COG1113	amino acid transport
HV340_RS03615	COG2186	Transcriptional regulator
HV340_RS03620	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV340_RS03625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV340_RS03630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV340_RS03640	COG3064	Membrane
HV340_RS03655	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HV340_RS03660	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HV340_RS03670	COG2132	Multicopper oxidase
HV340_RS03675	COG4993	Dehydrogenase
HV340_RS03680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HV340_RS03685	COG0288	reversible hydration of carbon dioxide
HV340_RS03690	COG1131	(ABC) transporter
HV340_RS03695	COG0842	Transport permease protein
HV340_RS03700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS03705	COG0726	polysaccharide deacetylase
HV340_RS03710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HV340_RS03715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HV340_RS03725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV340_RS03730	COG0617	tRNA 3'-terminal CCA addition
HV340_RS03745	COG1489	DNA binding
HV340_RS03750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV340_RS03755	COG1643	Atp-dependent helicase
HV340_RS03760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV340_RS03765	COG4774	siderophore transport
HV340_RS03770	COG1120	ATPase activity
HV340_RS03775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV340_RS03780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS03785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HV340_RS03800	COG2860	membrane
HV340_RS03805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV340_RS03810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV340_RS03815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HV340_RS03825	COG3835	regulator
HV340_RS03855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HV340_RS03870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV340_RS03880	COG0575	Belongs to the CDS family
HV340_RS03885	COG0750	zinc metalloprotease
HV340_RS03890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV340_RS03900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV340_RS03905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HV340_RS03915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV340_RS03920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HV340_RS03940	COG0346	lactoylglutathione lyase activity
HV340_RS03945	COG0037	tRNA processing
HV340_RS03950	COG4568	rho-dependent transcription termination
HV340_RS03965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV340_RS03970	COG3015	lipoprotein NlpE involved in copper resistance
HV340_RS03975	COG0442	prolyl-tRNA aminoacylation
HV340_RS03980	COG1720	tRNA m6t6A37 methyltransferase activity
HV340_RS03990	COG1464	Belongs to the NlpA lipoprotein family
HV340_RS03995	COG2011	ABC-type metal ion transport system permease component
HV340_RS04005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV340_RS04045	COG0583	DNA-binding transcription factor activity
HV340_RS04050	COG2814	Major facilitator Superfamily
HV340_RS04055	COG3021	interspecies interaction between organisms
HV340_RS04060	COG2226	methyltransferase
HV340_RS04065	COG1388	LysM domain
HV340_RS04065	COG0741	lytic transglycosylase activity
HV340_RS04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV340_RS04075	COG2226	methyltransferase
HV340_RS04085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV340_RS04100	COG0444	Belongs to the ABC transporter superfamily
HV340_RS04105	COG4608	Belongs to the ABC transporter superfamily
HV340_RS04130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV340_RS04135	COG1960	acyl-CoA dehydrogenase activity
HV340_RS04145	COG0121	glutamine amidotransferase
HV340_RS04150	COG3034	peptidoglycan biosynthetic process
HV340_RS04165	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV340_RS04170	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV340_RS04185	COG2991	Protein conserved in bacteria
HV340_RS04190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV340_RS04195	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV340_RS04215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV340_RS04220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV340_RS04225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HV340_RS04235	COG0582	viral genome integration into host DNA
HV340_RS04250	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV340_RS04260	COG0629	single-stranded DNA binding
HV340_RS04270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV340_RS04320	COG0305	Participates in initiation and elongation during chromosome replication
HV340_RS04400	COG3179	chitinase
HV340_RS04425	COG1783	phage Terminase large subunit
HV340_RS04540	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS04545	COG0583	DNA-binding transcription factor activity
HV340_RS04560	COG0628	permease
HV340_RS04565	COG0833	amino acid
HV340_RS04570	COG2040	homocysteine
HV340_RS04575	COG4521	taurine ABC transporter
HV340_RS04580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV340_RS04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV340_RS04590	COG2175	clavaminate synthase activity
HV340_RS04600	COG0113	porphobilinogen synthase activity
HV340_RS04615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV340_RS04625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV340_RS04645	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV340_RS04665	COG1785	Belongs to the alkaline phosphatase family
HV340_RS04675	COG3706	GGDEF domain
HV340_RS04680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV340_RS04685	COG1671	Belongs to the UPF0178 family
HV340_RS04690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV340_RS04700	COG4126	flavin adenine dinucleotide binding
HV340_RS04705	COG3123	guanosine phosphorylase activity
HV340_RS04715	COG1940	carbohydrate kinase activity
HV340_RS04720	COG0419	ATPase involved in DNA repair
HV340_RS04725	COG0420	3'-5' exonuclease activity
HV340_RS04735	COG5002	protein histidine kinase activity
HV340_RS04750	COG0366	Alpha amylase catalytic
HV340_RS04755	COG1335	isochorismatase
HV340_RS04765	COG1228	amidohydrolase
HV340_RS04770	COG0450	alkyl hydroperoxide reductase
HV340_RS04775	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HV340_RS04790	COG1862	Preprotein translocase
HV340_RS04795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV340_RS04800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV340_RS04815	COG3248	Nucleoside-binding outer membrane protein
HV340_RS04820	COG4238	major outer membrane lipoprotein
HV340_RS04825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HV340_RS04830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV340_RS04830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV340_RS04835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HV340_RS04840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HV340_RS04845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV340_RS04850	COG0667	Aldo Keto reductase
HV340_RS04855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV340_RS04860	COG0142	geranyltranstransferase activity
HV340_RS04880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HV340_RS04890	COG2814	Major facilitator Superfamily
HV340_RS04895	COG0109	protoheme IX farnesyltransferase activity
HV340_RS04900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV340_RS04905	COG1845	cytochrome c oxidase, subunit III
HV340_RS04910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV340_RS04915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV340_RS04920	COG2223	nitrite transmembrane transporter activity
HV340_RS04925	COG3056	Lipoprotein
HV340_RS04930	COG0271	Belongs to the BolA IbaG family
HV340_RS04935	COG0544	peptidyl-prolyl cis-trans isomerase activity
HV340_RS04945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HV340_RS04950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV340_RS04955	COG0776	regulation of translation
HV340_RS04960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV340_RS04965	COG1555	photosystem II stabilization
HV340_RS04970	COG0824	Thioesterase
HV340_RS04975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HV340_RS04980	COG4533	DNA binding
HV340_RS04985	COG0561	phosphatase activity
HV340_RS04995	COG1522	sequence-specific DNA binding
HV340_RS05000	COG1132	(ABC) transporter
HV340_RS05005	COG1132	(ABC) transporter
HV340_RS05010	COG0347	Belongs to the P(II) protein family
HV340_RS05015	COG0004	ammonium transporteR
HV340_RS05020	COG1946	Acyl-CoA thioesterase
HV340_RS05025	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV340_RS05030	COG3695	enzyme binding
HV340_RS05050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV340_RS05055	COG2364	Membrane
HV340_RS05060	COG1609	Transcriptional regulator
HV340_RS05080	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV340_RS05090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HV340_RS05110	COG0110	maltose O-acetyltransferase activity
HV340_RS05125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV340_RS05130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS05135	COG1309	transcriptional regulator
HV340_RS05140	COG1196	nuclear chromosome segregation
HV340_RS05140	COG3264	Mechanosensitive ion channel
HV340_RS05150	COG3923	Primosomal replication protein n
HV340_RS05155	COG2832	Protein of unknown function (DUF454)
HV340_RS05160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HV340_RS05170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HV340_RS05175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HV340_RS05180	COG0326	Molecular chaperone. Has ATPase activity
HV340_RS05190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HV340_RS05195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV340_RS05200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV340_RS05200	COG4651	solute:proton antiporter activity
HV340_RS05205	COG2223	nitrite transmembrane transporter activity
HV340_RS05220	COG3735	TraB family
HV340_RS05235	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV340_RS05240	COG0330	HflC and HflK could
HV340_RS05245	COG4619	ABC transporter
HV340_RS05250	COG0390	transport system, permease component
HV340_RS05255	COG3118	belongs to the thioredoxin family
HV340_RS05260	COG0300	oxidoreductase activity
HV340_RS05265	COG2755	lipolytic protein G-D-S-L family
HV340_RS05270	COG4181	ATPase activity
HV340_RS05275	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV340_RS05290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV340_RS05295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV340_RS05305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV340_RS05310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV340_RS05320	COG1988	membrane-bound metal-dependent
HV340_RS05325	COG1609	Transcriptional regulator
HV340_RS05330	COG1263	PTS System
HV340_RS05330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS05330	COG2190	(PTS) system
HV340_RS05335	COG2501	S4 domain
HV340_RS05450	COG1113	amino acid transport
HV340_RS05455	COG2211	Major facilitator Superfamily
HV340_RS05465	COG0673	inositol 2-dehydrogenase activity
HV340_RS05470	COG1609	Transcriptional regulator
HV340_RS05475	COG0668	transmembrane transport
HV340_RS05480	COG0477	Major facilitator Superfamily
HV340_RS05495	COG0778	Nitroreductase
HV340_RS05500	COG2315	Protein conserved in bacteria
HV340_RS05515	COG2207	Transcriptional regulator
HV340_RS05540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HV340_RS05550	COG2207	Transcriptional regulator
HV340_RS05565	COG1566	PFAM secretion protein HlyD family protein
HV340_RS05585	COG2197	response regulator
HV340_RS05590	COG1335	isochorismatase
HV340_RS05595	COG4977	sequence-specific DNA binding
HV340_RS05665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV340_RS05670	COG1505	serine-type exopeptidase activity
HV340_RS05695	COG2977	Belongs to the P-Pant transferase superfamily
HV340_RS05700	COG4771	TonB-dependent receptor
HV340_RS05705	COG2382	esterase
HV340_RS05710	COG3251	PFAM MbtH domain protein
HV340_RS05715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV340_RS05715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV340_RS05720	COG1120	ATPase activity
HV340_RS05725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS05730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS05740	COG4592	Periplasmic binding protein
HV340_RS05745	COG1169	isochorismate synthase
HV340_RS05750	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV340_RS05755	COG3433	isochorismatase activity
HV340_RS05755	COG1535	isochorismatase
HV340_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS05765	COG2050	protein possibly involved in aromatic compounds catabolism
HV340_RS05775	COG0700	Nucleoside recognition
HV340_RS05780	COG3366	ferrous iron transmembrane transporter activity
HV340_RS05785	COG1966	Carbon starvation protein
HV340_RS05790	COG2879	small protein
HV340_RS05800	COG0371	Dehydrogenase
HV340_RS05805	COG1129	ABC transporter
HV340_RS05810	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS05825	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HV340_RS05845	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HV340_RS05850	COG0235	Class ii aldolase
HV340_RS05855	COG0436	Aminotransferase
HV340_RS05860	COG0583	DNA-binding transcription factor activity
HV340_RS05880	COG1063	alcohol dehydrogenase
HV340_RS05885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV340_RS05900	COG3719	Belongs to the RNase T2 family
HV340_RS05905	COG3069	C4-dicarboxylate transmembrane transporter activity
HV340_RS05920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HV340_RS05925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV340_RS05930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV340_RS05935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HV340_RS05940	COG0583	DNA-binding transcription factor activity
HV340_RS05945	COG0321	lipoyl(octanoyl) transferase activity
HV340_RS05955	COG1686	Belongs to the peptidase S11 family
HV340_RS05960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV340_RS05965	COG0772	Belongs to the SEDS family
HV340_RS05970	COG0768	penicillin binding
HV340_RS05980	COG0799	negative regulation of ribosome biogenesis
HV340_RS05990	COG1466	dna polymerase III delta subunit
HV340_RS06005	COG2888	peptidyl-tyrosine sulfation
HV340_RS06010	COG1957	nucleoside hydrolase
HV340_RS06015	COG1126	abc transporter atp-binding protein
HV340_RS06020	COG0765	amino acid transport
HV340_RS06025	COG0765	amino acid transport
HV340_RS06045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV340_RS06050	COG1702	phosphate starvation-inducible protein PhoH
HV340_RS06060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV340_RS06100	COG0367	asparagine synthase
HV340_RS06105	COG0647	UMP catabolic process
HV340_RS06110	COG1940	carbohydrate kinase activity
HV340_RS06110	COG1846	Transcriptional regulator
HV340_RS06115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV340_RS06130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HV340_RS06145	COG0735	belongs to the Fur family
HV340_RS06160	COG0596	Alpha beta hydrolase
HV340_RS06165	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HV340_RS06170	COG0033	Phosphoglucomutase
HV340_RS06175	COG0531	amino acid
HV340_RS06180	COG1982	Orn Lys Arg decarboxylase major
HV340_RS06190	COG0745	RESPONSE REGULATOR receiver
HV340_RS06195	COG2205	protein histidine kinase activity
HV340_RS06200	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HV340_RS06205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HV340_RS06210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HV340_RS06230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HV340_RS06235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV340_RS06240	COG1984	allophanate hydrolase subunit 2
HV340_RS06250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HV340_RS06255	COG0372	Belongs to the citrate synthase family
HV340_RS06260	COG2009	succinate dehydrogenase
HV340_RS06265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV340_RS06270	COG1053	succinate dehydrogenase
HV340_RS06275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV340_RS06280	COG0567	Dehydrogenase, E1 component
HV340_RS06285	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV340_RS06290	COG0045	succinate-CoA ligase (ADP-forming) activity
HV340_RS06295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV340_RS06300	COG2188	Transcriptional regulator
HV340_RS06305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV340_RS06305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV340_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS06310	COG0383	alpha-mannosidase activity
HV340_RS06315	COG1271	oxidase subunit
HV340_RS06320	COG1294	oxidase, subunit
HV340_RS06325	COG4890	Cyd operon protein YbgT
HV340_RS06330	COG3790	cyd operon protein YbgE
HV340_RS06335	COG0824	Thioesterase
HV340_RS06340	COG0811	peptide transport
HV340_RS06345	COG0848	biopolymer transport protein
HV340_RS06350	COG3064	Membrane
HV340_RS06360	COG2885	chlorophyll binding
HV340_RS06365	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV340_RS06400	COG3201	nicotinamide mononucleotide transporter
HV340_RS06405	COG1230	cation diffusion facilitator family transporter
HV340_RS06415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV340_RS06425	COG2017	converts alpha-aldose to the beta-anomer
HV340_RS06430	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HV340_RS06435	COG1085	galactose-1-phosphate uridylyltransferase
HV340_RS06440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HV340_RS06445	COG1119	ATPase activity
HV340_RS06450	COG2005	Transcriptional regulator
HV340_RS06450	COG3585	molybdate ion transport
HV340_RS06460	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV340_RS06465	COG4149	molybdate abc transporter
HV340_RS06475	COG0561	phosphatase activity
HV340_RS06480	COG2706	6-phosphogluconolactonase activity
HV340_RS06485	COG4677	pectinesterase activity
HV340_RS06495	COG0010	Belongs to the arginase family
HV340_RS06505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HV340_RS06510	COG2986	histidine ammonia-lyase
HV340_RS06515	COG1881	PFAM PEBP family protein
HV340_RS06520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV340_RS06525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HV340_RS06530	COG0156	8-amino-7-oxononanoate synthase activity
HV340_RS06535	COG2226	methyltransferase
HV340_RS06545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HV340_RS06565	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV340_RS06570	COG0315	cyclic pyranopterin monophosphate synthase activity
HV340_RS06575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV340_RS06580	COG0314	molybdopterin synthase activity
HV340_RS06585	COG0670	Belongs to the BI1 family
HV340_RS06590	COG0392	lysyltransferase activity
HV340_RS06595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV340_RS06600	COG3568	Endonuclease Exonuclease Phosphatase
HV340_RS06610	COG0842	Transport permease protein
HV340_RS06615	COG0842	Transport permease protein
HV340_RS06620	COG1131	(ABC) transporter
HV340_RS06625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS06630	COG1309	transcriptional regulator
HV340_RS06635	COG0513	Belongs to the DEAD box helicase family
HV340_RS06660	COG3121	Chaperone
HV340_RS06665	COG3539	Fimbrial protein
HV340_RS06670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV340_RS06680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV340_RS06690	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HV340_RS06695	COG0668	transmembrane transport
HV340_RS06700	COG1126	abc transporter atp-binding protein
HV340_RS06705	COG0765	amino acid transport
HV340_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS06715	COG0783	Belongs to the Dps family
HV340_RS06725	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV340_RS06730	COG2194	sulfuric ester hydrolase activity
HV340_RS06740	COG1321	iron dependent repressor
HV340_RS06745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV340_RS06750	COG1566	PFAM secretion protein HlyD family protein
HV340_RS06755	COG2814	Major facilitator Superfamily
HV340_RS06765	COG0667	Aldo Keto reductase
HV340_RS06770	COG2723	6-phospho-beta-galactosidase activity
HV340_RS06775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS06780	COG2188	Transcriptional regulator
HV340_RS06785	COG1376	ErfK ybiS ycfS ynhG family protein
HV340_RS06795	COG3039	Transposase
HV340_RS06845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV340_RS06850	COG0488	(ABC) transporter
HV340_RS06860	COG2271	Major facilitator Superfamily
HV340_RS06865	COG1609	Transcriptional regulator
HV340_RS06875	COG0561	phosphatase activity
HV340_RS06880	COG1882	Formate acetyltransferase
HV340_RS06885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV340_RS06890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV340_RS06895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV340_RS06905	COG1446	asparaginase
HV340_RS06940	COG2133	pyrroloquinoline quinone binding
HV340_RS06945	COG0625	glutathione transferase activity
HV340_RS06950	COG1686	Belongs to the peptidase S11 family
HV340_RS06955	COG1349	DNA-binding transcription factor activity
HV340_RS06960	COG0671	phosphoesterase, PA-phosphatase related
HV340_RS06970	COG2814	Major facilitator Superfamily
HV340_RS06975	COG0561	phosphatase activity
HV340_RS06980	COG0738	Major facilitator superfamily
HV340_RS06985	COG3226	Transcriptional regulator
HV340_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS06995	COG1393	Belongs to the ArsC family
HV340_RS07000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV340_RS07005	COG0640	Transcriptional regulator
HV340_RS07010	COG0569	domain protein
HV340_RS07010	COG2985	domain, Protein
HV340_RS07025	COG0778	Nitroreductase
HV340_RS07030	COG0189	ligase activity
HV340_RS07040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV340_RS07045	COG3842	ATPase activity
HV340_RS07050	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV340_RS07055	COG1177	transmembrane transport
HV340_RS07065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV340_RS07070	COG0745	RESPONSE REGULATOR receiver
HV340_RS07075	COG5002	protein histidine kinase activity
HV340_RS07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS07085	COG4160	amino acid transport
HV340_RS07090	COG4215	(ABC) transporter
HV340_RS07095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS07100	COG1126	abc transporter atp-binding protein
HV340_RS07110	COG0393	Putative heavy-metal-binding
HV340_RS07115	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV340_RS07135	COG3031	protein transport across the cell outer membrane
HV340_RS07140	COG1450	Type ii and iii secretion system protein
HV340_RS07145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV340_RS07155	COG2165	general secretion pathway protein
HV340_RS07165	COG2165	general secretion pathway protein
HV340_RS07175	COG3156	type II secretion system protein K
HV340_RS07190	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HV340_RS07205	COG3397	chitin binding
HV340_RS07210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV340_RS07215	COG0702	epimerase
HV340_RS07220	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV340_RS07225	COG0028	Belongs to the TPP enzyme family
HV340_RS07235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV340_RS07240	COG1151	hydroxylamine reductase activity
HV340_RS07245	COG2431	L-lysine efflux transmembrane transporter activity
HV340_RS07255	COG3593	DNA synthesis involved in DNA repair
HV340_RS07260	COG2990	Protein conserved in bacteria
HV340_RS07265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS07275	COG1278	Cold shock
HV340_RS07280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HV340_RS07285	COG0542	response to heat
HV340_RS07295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV340_RS07300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HV340_RS07305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV340_RS07310	COG4988	ABC transporter
HV340_RS07315	COG0492	ferredoxin-NADP+ reductase activity
HV340_RS07330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HV340_RS07335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV340_RS07340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HV340_RS07345	COG0243	molybdopterin cofactor binding
HV340_RS07350	COG0437	4 iron, 4 sulfur cluster binding
HV340_RS07355	COG3302	dmso reductase anchor subunit
HV340_RS07360	COG0477	Major facilitator Superfamily
HV340_RS07370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV340_RS07375	COG1882	Formate acetyltransferase
HV340_RS07380	COG2116	formate transmembrane transporter activity
HV340_RS07385	COG1944	ATP diphosphatase activity
HV340_RS07390	COG2323	membrane
HV340_RS07395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HV340_RS07400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HV340_RS07405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HV340_RS07410	COG0539	negative regulation of cytoplasmic translation
HV340_RS07415	COG0776	regulation of translation
HV340_RS07420	COG2333	competence protein COMEC
HV340_RS07420	COG0658	competence protein
HV340_RS07425	COG1132	(ABC) transporter
HV340_RS07430	COG1663	tetraacyldisaccharide 4'-kinase activity
HV340_RS07435	COG3214	Protein conserved in bacteria
HV340_RS07440	COG2835	tetraacyldisaccharide 4'-kinase activity
HV340_RS07445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HV340_RS07450	COG3173	Aminoglycoside phosphotransferase
HV340_RS07455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV340_RS07460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV340_RS07470	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV340_RS07475	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HV340_RS07480	COG2989	Protein conserved in bacteria
HV340_RS07485	COG3108	Peptidase M15
HV340_RS07490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV340_RS07495	COG1448	Aminotransferase
HV340_RS07505	COG0017	Asparaginyl-tRNA synthetase
HV340_RS07510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HV340_RS07525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HV340_RS07550	COG0308	aminopeptidase N
HV340_RS07560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV340_RS07565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS07570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV340_RS07575	COG0431	NADPH-dependent FMN reductase
HV340_RS07580	COG0167	dihydroorotate dehydrogenase activity
HV340_RS07590	COG3217	Mosc domain protein beta barrel domain protein
HV340_RS07590	COG0633	Ferredoxin
HV340_RS07595	COG0116	Belongs to the methyltransferase superfamily
HV340_RS07595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HV340_RS07600	COG0488	(ABC) transporter
HV340_RS07605	COG2995	paraquat-inducible protein a
HV340_RS07610	COG3008	intermembrane lipid transfer
HV340_RS07610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV340_RS07615	COG3009	Protein conserved in bacteria
HV340_RS07620	COG3130	regulation of translation
HV340_RS07630	COG1067	ATP-dependent peptidase activity
HV340_RS07635	COG3120	sequence-specific DNA binding
HV340_RS07645	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
HV340_RS07650	COG3070	regulator of competence-specific genes
HV340_RS07655	COG1289	transmembrane transporter activity
HV340_RS07660	COG3304	Inner membrane component domain
HV340_RS07665	COG0210	DNA helicase
HV340_RS07670	COG1803	Methylglyoxal synthase
HV340_RS07675	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HV340_RS07680	COG1832	CoA-binding protein
HV340_RS07690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HV340_RS07695	COG1881	PFAM PEBP family protein
HV340_RS07705	COG1254	Belongs to the acylphosphatase family
HV340_RS07710	COG2920	part of a sulfur-relay system
HV340_RS07715	COG0670	Belongs to the BI1 family
HV340_RS07815	COG2351	hydroxyisourate hydrolase activity
HV340_RS07820	COG0402	S-adenosylhomocysteine deaminase activity
HV340_RS07825	COG1953	Uracil, thiamine, allantoin
HV340_RS07880	COG0765	amino acid transport
HV340_RS07890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HV340_RS07905	COG2182	Extracellular solute-binding protein
HV340_RS07910	COG1175	transmembrane transport
HV340_RS07915	COG3833	ABC-type maltose transport systems, permease component
HV340_RS07920	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HV340_RS07925	COG1874	Beta-galactosidase
HV340_RS07945	COG2239	Acts as a magnesium transporter
HV340_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS07960	COG1733	regulation of RNA biosynthetic process
HV340_RS07980	COG3729	General stress protein
HV340_RS07990	COG2233	PERMEase
HV340_RS07995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV340_RS08000	COG0778	Nitroreductase
HV340_RS08005	COG2267	carboxylic ester hydrolase activity
HV340_RS08010	COG0251	oxidation-reduction process
HV340_RS08015	COG1335	isochorismatase
HV340_RS08020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS08025	COG1309	transcriptional regulator
HV340_RS08035	COG0506	proline dehydrogenase activity
HV340_RS08035	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV340_RS08035	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV340_RS08040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV340_RS08050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV340_RS08060	COG2822	iron ion transport
HV340_RS08070	COG1702	phosphate starvation-inducible protein PhoH
HV340_RS08090	COG1335	isochorismatase
HV340_RS08100	COG0583	DNA-binding transcription factor activity
HV340_RS08115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV340_RS08120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HV340_RS08125	COG3381	protein complex oligomerization
HV340_RS08175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HV340_RS08190	COG2943	transferase activity, transferring hexosyl groups
HV340_RS08195	COG5645	(Lipo)protein
HV340_RS08210	COG1560	Kdo2-lipid A biosynthetic process
HV340_RS08220	COG2353	YceI-like domain
HV340_RS08225	COG3038	cytochrome b561
HV340_RS08250	COG0418	dihydroorotase activity
HV340_RS08260	COG0477	Major facilitator Superfamily
HV340_RS08265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV340_RS08270	COG3132	Protein of unknown function, DUF480
HV340_RS08275	COG0673	inositol 2-dehydrogenase activity
HV340_RS08305	COG1558	bacterial-type flagellum-dependent cell motility
HV340_RS08315	COG1749	Flagellar hook protein flgE
HV340_RS08320	COG4787	bacterial-type flagellum-dependent cell motility
HV340_RS08325	COG4786	Flagellar basal body rod
HV340_RS08345	COG1256	bacterial-type flagellum assembly
HV340_RS08355	COG2814	Major facilitator Superfamily
HV340_RS08360	COG0583	DNA-binding transcription factor activity
HV340_RS08365	COG1530	ribonuclease E activity
HV340_RS08370	COG0564	pseudouridine synthase activity
HV340_RS08385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HV340_RS08390	COG0416	fatty acid biosynthetic process
HV340_RS08395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HV340_RS08410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HV340_RS08415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV340_RS08420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV340_RS08425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV340_RS08430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HV340_RS08435	COG0470	DNA polymerase III
HV340_RS08440	COG0084	hydrolase, TatD family'
HV340_RS08445	COG1263	PTS System
HV340_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS08450	COG4773	Receptor
HV340_RS08455	COG0537	adenosine 5'-monophosphoramidase activity
HV340_RS08460	COG5633	Lipoprotein
HV340_RS08465	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HV340_RS08480	COG3150	esterase
HV340_RS08485	COG1252	NADH dehydrogenase
HV340_RS08490	COG3134	Outer membrane lipoprotein
HV340_RS08495	COG1309	transcriptional regulator
HV340_RS08505	COG1388	LysM domain
HV340_RS08505	COG1376	ErfK ybiS ycfS ynhG family protein
HV340_RS08510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV340_RS08515	COG4763	Acyl-transferase
HV340_RS08520	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV340_RS08525	COG1136	(ABC) transporter
HV340_RS08530	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV340_RS08540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV340_RS08545	COG0840	transmembrane signaling receptor activity
HV340_RS08550	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HV340_RS08580	COG2850	peptidyl-arginine hydroxylation
HV340_RS08595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV340_RS08600	COG2915	High frequency lysogenization protein hflD homolog
HV340_RS08620	COG0538	isocitrate dehydrogenase activity
HV340_RS08625	COG4124	Belongs to the glycosyl hydrolase 26 family
HV340_RS08650	COG2200	EAL domain
HV340_RS08655	COG3706	GGDEF domain
HV340_RS08655	COG5001	Diguanylate cyclase
HV340_RS08655	COG4251	negative regulation of phosphorylation
HV340_RS08655	COG2203	Gaf domain
HV340_RS08660	COG2261	transglycosylase associated protein
HV340_RS08675	COG2199	diguanylate cyclase activity
HV340_RS08675	COG2203	Gaf domain
HV340_RS08680	COG3042	response to heat
HV340_RS08690	COG3189	MarR family transcriptional regulator
HV340_RS08695	COG0504	CTP synthase activity
HV340_RS08700	COG2807	transmembrane transport
HV340_RS08705	COG2207	Transcriptional regulator
HV340_RS08710	COG2707	UPF0756 membrane protein
HV340_RS08715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV340_RS08725	COG2718	Belongs to the UPF0229 family
HV340_RS08730	COG2766	serine protein kinase
HV340_RS08785	COG2199	diguanylate cyclase activity
HV340_RS08785	COG2200	EAL domain
HV340_RS08875	COG3713	MltA-interacting MipA family protein
HV340_RS08880	COG0656	L-ascorbic acid biosynthetic process
HV340_RS08900	COG3139	Protein of unknown function (DUF1315)
HV340_RS08910	COG1335	isochorismatase
HV340_RS08915	COG0252	asparaginase activity
HV340_RS08920	COG0616	signal peptide processing
HV340_RS08925	COG0778	Nitroreductase
HV340_RS08930	COG0709	Synthesizes selenophosphate from selenide and ATP
HV340_RS08935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV340_RS08950	COG0494	nUDIX hydrolase
HV340_RS08955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV340_RS08960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV340_RS08965	COG2897	thiosulfate sulfurtransferase activity
HV340_RS08970	COG4136	ATPase activity
HV340_RS08975	COG4135	transport system, permease component
HV340_RS08980	COG4134	Bacterial extracellular solute-binding protein
HV340_RS08990	COG0708	Exodeoxyribonuclease III
HV340_RS09000	COG3138	arginine N-succinyltransferase
HV340_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS09010	COG3724	N-succinylarginine dihydrolase activity
HV340_RS09020	COG3678	ATP-independent chaperone mediated protein folding
HV340_RS09030	COG0322	excinuclease ABC activity
HV340_RS09035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HV340_RS09040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV340_RS09045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS09050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS09055	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV340_RS09060	COG2169	Transcriptional regulator
HV340_RS09060	COG1917	Cupin 2, conserved barrel domain protein
HV340_RS09065	COG1486	melibiose metabolic process
HV340_RS09070	COG3394	polysaccharide catabolic process
HV340_RS09075	COG0753	catalase activity
HV340_RS09090	COG1988	membrane-bound metal-dependent
HV340_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS09100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV340_RS09110	COG3001	Fructosamine kinase
HV340_RS09120	COG1105	Belongs to the carbohydrate kinase PfkB family
HV340_RS09125	COG3137	Salt-induced outer membrane protein
HV340_RS09155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HV340_RS09170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HV340_RS09180	COG0776	regulation of translation
HV340_RS09190	COG0386	Belongs to the glutathione peroxidase family
HV340_RS09200	COG0791	NLP P60 protein
HV340_RS09210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HV340_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS09220	COG2610	gluconate transmembrane transporter activity
HV340_RS09235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV340_RS09240	COG0583	DNA-binding transcription factor activity
HV340_RS09250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS09255	COG4558	Periplasmic binding protein
HV340_RS09260	COG3720	iron ion transport
HV340_RS09270	COG4256	Hemin uptake protein
HV340_RS09280	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HV340_RS09285	COG0574	Belongs to the PEP-utilizing enzyme family
HV340_RS09285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV340_RS09290	COG2211	Major facilitator Superfamily
HV340_RS09295	COG1472	Belongs to the glycosyl hydrolase 3 family
HV340_RS09305	COG0628	permease
HV340_RS09310	COG0277	FAD linked oxidase domain protein
HV340_RS09310	COG0247	lactate metabolic process
HV340_RS09315	COG2050	protein possibly involved in aromatic compounds catabolism
HV340_RS09325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV340_RS09335	COG3539	Fimbrial protein
HV340_RS09340	COG3121	Chaperone
HV340_RS09370	COG3383	formate dehydrogenase (NAD+) activity
HV340_RS09390	COG2200	EAL domain
HV340_RS09395	COG0789	Transcriptional regulator
HV340_RS09400	COG0316	Belongs to the HesB IscA family
HV340_RS09405	COG0719	Fe-S assembly protein
HV340_RS09410	COG0396	ATPase activity
HV340_RS09415	COG0719	Fe-S assembly protein
HV340_RS09420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV340_RS09425	COG2166	iron-sulfur cluster assembly
HV340_RS09430	COG1376	ErfK ybiS ycfS ynhG family protein
HV340_RS09445	COG0626	cystathionine gamma-synthase activity
HV340_RS09460	COG2011	ABC-type metal ion transport system permease component
HV340_RS09465	COG1464	Belongs to the NlpA lipoprotein family
HV340_RS09475	COG0765	amino acid transport
HV340_RS09480	COG0765	amino acid transport
HV340_RS09490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS09500	COG4191	Histidine kinase
HV340_RS09505	COG4566	intracellular signal transduction
HV340_RS09520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV340_RS09530	COG4529	Protein conserved in bacteria
HV340_RS09545	COG0534	Mate efflux family protein
HV340_RS09550	COG0307	riboflavin synthase, alpha
HV340_RS09555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV340_RS09560	COG2814	Major facilitator Superfamily
HV340_RS09565	COG0583	DNA-binding transcription factor activity
HV340_RS09580	COG2814	Major facilitator Superfamily
HV340_RS09590	COG0791	NLP P60 protein
HV340_RS09595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV340_RS09600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV340_RS09605	COG0346	lactoylglutathione lyase activity
HV340_RS09610	COG1902	pentaerythritol trinitrate reductase activity
HV340_RS09615	COG1309	transcriptional regulator
HV340_RS09620	COG2194	sulfuric ester hydrolase activity
HV340_RS09625	COG3313	Fe-S protein
HV340_RS09630	COG4989	oxidoreductase activity
HV340_RS09635	COG2032	superoxide dismutase activity
HV340_RS09645	COG1566	PFAM secretion protein HlyD family protein
HV340_RS09660	COG3706	GGDEF domain
HV340_RS09670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HV340_RS09675	COG3895	Periplasmic Protein
HV340_RS09680	COG0259	pyridoxamine-phosphate oxidase activity
HV340_RS09685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HV340_RS09690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HV340_RS09695	COG0625	glutathione transferase activity
HV340_RS09700	COG3104	oligopeptide transport
HV340_RS09705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV340_RS09755	COG0673	inositol 2-dehydrogenase activity
HV340_RS09760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HV340_RS09765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV340_RS09770	COG1263	PTS System
HV340_RS09770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS09775	COG1609	Transcriptional regulator
HV340_RS09780	COG5339	Protein conserved in bacteria
HV340_RS09785	COG1482	cell wall glycoprotein biosynthetic process
HV340_RS09790	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV340_RS09790	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV340_RS09805	COG2205	protein histidine kinase activity
HV340_RS09810	COG0745	RESPONSE REGULATOR receiver
HV340_RS09815	COG3136	membrane protein required for alginate biosynthesis
HV340_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS09825	COG0531	amino acid
HV340_RS09835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV340_RS09840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV340_RS09865	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HV340_RS09870	COG1473	amidohydrolase
HV340_RS09880	COG0583	DNA-binding transcription factor activity
HV340_RS09885	COG2840	Smr protein MutS2
HV340_RS09895	COG0667	Aldo Keto reductase
HV340_RS09900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV340_RS09910	COG0583	DNA-binding transcription factor activity
HV340_RS09920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV340_RS09925	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV340_RS09935	COG1403	HNH endonuclease
HV340_RS09940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS09945	COG0628	permease
HV340_RS09950	COG2076	Multidrug Resistance protein
HV340_RS09955	COG2076	Multidrug Resistance protein
HV340_RS09960	COG5001	Diguanylate cyclase
HV340_RS09965	COG3591	Belongs to the peptidase S1B family
HV340_RS09975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV340_RS09985	COG2814	Major facilitator Superfamily
HV340_RS09990	COG0583	DNA-binding transcription factor activity
HV340_RS09995	COG1940	carbohydrate kinase activity
HV340_RS10000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV340_RS10035	COG0625	glutathione transferase activity
HV340_RS10060	COG1116	anion transmembrane transporter activity
HV340_RS10060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV340_RS10065	COG3665	Urea carboxylase-associated protein
HV340_RS10070	COG3665	Urea carboxylase-associated protein
HV340_RS10075	COG0439	Biotin carboxylase
HV340_RS10085	COG3381	protein complex oligomerization
HV340_RS10090	COG3302	dmso reductase anchor subunit
HV340_RS10095	COG0437	4 iron, 4 sulfur cluster binding
HV340_RS10100	COG0243	molybdopterin cofactor binding
HV340_RS10130	COG0243	molybdopterin cofactor binding
HV340_RS10150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV340_RS10160	COG1742	UPF0060 membrane protein
HV340_RS10165	COG4948	Mandelate Racemase Muconate Lactonizing
HV340_RS10170	COG1063	alcohol dehydrogenase
HV340_RS10175	COG0477	Major facilitator Superfamily
HV340_RS10180	COG0246	Mannitol dehydrogenase
HV340_RS10190	COG0589	response to stress
HV340_RS10195	COG1802	Transcriptional regulator
HV340_RS10200	COG4221	oxidoreductase activity
HV340_RS10230	COG3188	usher protein
HV340_RS10250	COG2771	luxR family
HV340_RS10250	COG2200	EAL domain
HV340_RS10290	COG1309	transcriptional regulator
HV340_RS10300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV340_RS10305	COG2911	Protein conserved in bacteria
HV340_RS10315	COG3784	Protein of unknown function (DUF1318)
HV340_RS10320	COG2207	Transcriptional regulator
HV340_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS10330	COG4251	negative regulation of phosphorylation
HV340_RS10330	COG3706	GGDEF domain
HV340_RS10330	COG2203	Gaf domain
HV340_RS10330	COG5001	Diguanylate cyclase
HV340_RS10340	COG2030	dehydratase
HV340_RS10340	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS10345	COG3396	Phenylacetate-CoA oxygenase
HV340_RS10350	COG3460	Phenylacetate-CoA oxygenase
HV340_RS10355	COG3396	Phenylacetate-CoA oxygenase
HV340_RS10360	COG2151	metal-sulfur cluster biosynthetic enzyme
HV340_RS10365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV340_RS10370	COG1024	Enoyl-CoA hydratase
HV340_RS10375	COG1024	Enoyl-CoA hydratase
HV340_RS10380	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV340_RS10385	COG2050	protein possibly involved in aromatic compounds catabolism
HV340_RS10390	COG0183	Belongs to the thiolase family
HV340_RS10395	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV340_RS10400	COG3327	negative regulation of DNA-templated transcription, initiation
HV340_RS10405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV340_RS10415	COG0583	DNA-binding transcription factor activity
HV340_RS10430	COG0583	DNA-binding transcription factor activity
HV340_RS10450	COG0300	oxidoreductase activity
HV340_RS10455	COG0789	Transcriptional regulator
HV340_RS10460	COG0583	DNA-binding transcription factor activity
HV340_RS10465	COG1902	pentaerythritol trinitrate reductase activity
HV340_RS10505	COG0300	oxidoreductase activity
HV340_RS10520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV340_RS10565	COG3122	Protein conserved in bacteria
HV340_RS10580	COG1643	Atp-dependent helicase
HV340_RS10585	COG4122	O-methyltransferase activity
HV340_RS10590	COG1538	Outer membrane efflux protein
HV340_RS10605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV340_RS10610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV340_RS10615	COG3038	cytochrome b561
HV340_RS10620	COG0673	inositol 2-dehydrogenase activity
HV340_RS10625	COG1349	DNA-binding transcription factor activity
HV340_RS10665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV340_RS10680	COG0840	transmembrane signaling receptor activity
HV340_RS10685	COG4993	Dehydrogenase
HV340_RS10690	COG0583	DNA-binding transcription factor activity
HV340_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS10700	COG3111	PFAM Bacterial OB fold (BOF) protein
HV340_RS10710	COG2323	membrane
HV340_RS10715	COG1546	Belongs to the CinA family
HV340_RS10730	COG1294	oxidase, subunit
HV340_RS10735	COG1271	oxidase subunit
HV340_RS10740	COG3546	catalase activity
HV340_RS10745	COG3685	Protein conserved in bacteria
HV340_RS10755	COG3685	Protein conserved in bacteria
HV340_RS10760	COG3729	General stress protein
HV340_RS10765	COG5383	Protein conserved in bacteria
HV340_RS10770	COG2272	Belongs to the type-B carboxylesterase lipase family
HV340_RS10780	COG0436	Aminotransferase
HV340_RS10790	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HV340_RS10795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV340_RS10800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV340_RS10805	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV340_RS10810	COG0500	methyltransferase
HV340_RS10815	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV340_RS10820	COG0747	negative chemotaxis
HV340_RS10830	COG0697	spore germination
HV340_RS10840	COG3135	benzoate transporter
HV340_RS10845	COG1396	sequence-specific DNA binding
HV340_RS10850	COG0826	peptidase U32
HV340_RS10875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV340_RS10895	COG1129	ABC transporter
HV340_RS10905	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV340_RS10910	COG2814	Major facilitator Superfamily
HV340_RS10915	COG0697	spore germination
HV340_RS10930	COG1846	Transcriptional regulator
HV340_RS10940	COG2814	Major facilitator Superfamily
HV340_RS10960	COG0583	DNA-binding transcription factor activity
HV340_RS10970	COG0583	DNA-binding transcription factor activity
HV340_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS10980	COG0840	transmembrane signaling receptor activity
HV340_RS10985	COG2066	Belongs to the glutaminase family
HV340_RS10995	COG2199	diguanylate cyclase activity
HV340_RS11000	COG3706	GGDEF domain
HV340_RS11010	COG0246	Mannitol dehydrogenase
HV340_RS11015	COG3781	membrane
HV340_RS11025	COG0456	acetyltransferase
HV340_RS11030	COG0596	Alpha beta hydrolase
HV340_RS11035	COG0745	RESPONSE REGULATOR receiver
HV340_RS11050	COG4106	trans-aconitate 2-methyltransferase activity
HV340_RS11055	COG0494	nUDIX hydrolase
HV340_RS11070	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HV340_RS11070	COG3264	Mechanosensitive ion channel
HV340_RS11090	COG0667	Aldo Keto reductase
HV340_RS11100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV340_RS11125	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS11135	COG0745	RESPONSE REGULATOR receiver
HV340_RS11150	COG2814	Major facilitator Superfamily
HV340_RS11185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HV340_RS11195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HV340_RS11210	COG0583	DNA-binding transcription factor activity
HV340_RS11215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV340_RS11220	COG4628	conserved protein (DUF2132)
HV340_RS11230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV340_RS11285	COG0840	transmembrane signaling receptor activity
HV340_RS11315	COG2200	EAL domain
HV340_RS11330	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HV340_RS11335	COG0747	negative chemotaxis
HV340_RS11340	COG0601	transmembrane transport
HV340_RS11345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV340_RS11350	COG0444	Belongs to the ABC transporter superfamily
HV340_RS11355	COG4608	Belongs to the ABC transporter superfamily
HV340_RS11360	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS11370	COG1764	response to oxidative stress
HV340_RS11400	COG0281	malic enzyme
HV340_RS11405	COG0488	(ABC) transporter
HV340_RS11410	COG1064	alcohol dehydrogenase
HV340_RS11420	COG1252	NADH dehydrogenase
HV340_RS11425	COG2814	Major facilitator Superfamily
HV340_RS11435	COG2864	formate dehydrogenase
HV340_RS11440	COG0437	4 iron, 4 sulfur cluster binding
HV340_RS11475	COG2223	nitrite transmembrane transporter activity
HV340_RS11480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV340_RS11485	COG1140	nitrate reductase beta subunit
HV340_RS11490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV340_RS11495	COG2181	nitrate reductase activity
HV340_RS11500	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV340_RS11505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV340_RS11510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV340_RS11515	COG0640	Transcriptional regulator
HV340_RS11520	COG1942	4-Oxalocrotonate Tautomerase
HV340_RS11525	COG0625	glutathione transferase activity
HV340_RS11535	COG1126	abc transporter atp-binding protein
HV340_RS11555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS11560	COG1473	amidohydrolase
HV340_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS11570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HV340_RS11570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HV340_RS11575	COG0840	transmembrane signaling receptor activity
HV340_RS11590	COG4772	TonB-dependent receptor
HV340_RS11595	COG1802	Transcriptional regulator
HV340_RS11600	COG2130	NADP-dependent
HV340_RS11605	COG1396	sequence-specific DNA binding
HV340_RS11610	COG1247	-acetyltransferase
HV340_RS11615	COG3238	Protein conserved in bacteria
HV340_RS11625	COG0747	negative chemotaxis
HV340_RS11655	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS11660	COG1177	transmembrane transport
HV340_RS11665	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV340_RS11670	COG3842	ATPase activity
HV340_RS11675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV340_RS11680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV340_RS11690	COG1271	oxidase subunit
HV340_RS11695	COG1294	oxidase, subunit
HV340_RS11705	COG3187	Heat shock protein
HV340_RS11710	COG3042	response to heat
HV340_RS11715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV340_RS11715	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV340_RS11715	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV340_RS11715	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV340_RS11720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV340_RS11755	COG0513	Belongs to the DEAD box helicase family
HV340_RS11765	COG0840	transmembrane signaling receptor activity
HV340_RS11775	COG3706	GGDEF domain
HV340_RS11785	COG0693	protein deglycase activity
HV340_RS11795	COG4166	transmembrane transport
HV340_RS11800	COG2866	Carboxypeptidase
HV340_RS11805	COG4948	Mandelate Racemase Muconate Lactonizing
HV340_RS11810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV340_RS11825	COG3768	UPF0283 membrane protein
HV340_RS11830	COG3106	COG3106 Predicted ATPase
HV340_RS11835	COG1609	Transcriptional regulator
HV340_RS11845	COG3842	ATPase activity
HV340_RS11850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV340_RS11855	COG1554	hydrolase, family 65, central catalytic
HV340_RS11860	COG0673	inositol 2-dehydrogenase activity
HV340_RS11865	COG1082	Xylose isomerase domain protein TIM barrel
HV340_RS11870	COG1063	alcohol dehydrogenase
HV340_RS11875	COG0395	ABC-type sugar transport system, permease component
HV340_RS11880	COG1175	transmembrane transport
HV340_RS11885	COG1653	transport
HV340_RS11890	COG0366	Alpha amylase catalytic
HV340_RS11900	COG1983	PspC domain protein
HV340_RS11910	COG1842	Phage shock protein A
HV340_RS11915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV340_RS11930	COG4171	peptide transport system, permease
HV340_RS11940	COG4172	Belongs to the ABC transporter superfamily
HV340_RS11950	COG0251	oxidation-reduction process
HV340_RS11955	COG2207	Transcriptional regulator
HV340_RS11955	COG3708	Transcriptional regulator
HV340_RS11960	COG3706	GGDEF domain
HV340_RS11970	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV340_RS11975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV340_RS11975	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV340_RS11980	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HV340_RS11985	COG5001	Diguanylate cyclase
HV340_RS11990	COG1024	Enoyl-CoA hydratase
HV340_RS12000	COG1349	DNA-binding transcription factor activity
HV340_RS12010	COG0023	Translation Initiation Factor
HV340_RS12015	COG0284	orotidine-5'-phosphate decarboxylase activity
HV340_RS12020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV340_RS12025	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV340_RS12030	COG0671	phosphoesterase, PA-phosphatase related
HV340_RS12040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV340_RS12070	COG0616	signal peptide processing
HV340_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS12080	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HV340_RS12090	COG0009	L-threonylcarbamoyladenylate synthase
HV340_RS12110	COG0512	Glutamine amidotransferase of anthranilate synthase
HV340_RS12110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV340_RS12115	COG0135	phosphoribosylanthranilate isomerase activity
HV340_RS12115	COG0134	indole-3-glycerol-phosphate synthase activity
HV340_RS12125	COG0159	tryptophan synthase activity
HV340_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS12150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV340_RS12190	COG0656	L-ascorbic acid biosynthetic process
HV340_RS12195	COG0668	transmembrane transport
HV340_RS12200	COG1278	Cold shock
HV340_RS12225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HV340_RS12230	COG2271	Major facilitator Superfamily
HV340_RS12235	COG1846	Transcriptional regulator
HV340_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS12280	COG5002	protein histidine kinase activity
HV340_RS12285	COG0745	RESPONSE REGULATOR receiver
HV340_RS12295	COG0583	DNA-binding transcription factor activity
HV340_RS12305	COG1917	Cupin 2, conserved barrel domain protein
HV340_RS12305	COG4977	sequence-specific DNA binding
HV340_RS12310	COG4221	oxidoreductase activity
HV340_RS12315	COG4221	oxidoreductase activity
HV340_RS12325	COG0583	DNA-binding transcription factor activity
HV340_RS12330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV340_RS12335	COG0604	alcohol dehydrogenase
HV340_RS12360	COG2391	methyltransferase activity
HV340_RS12365	COG0425	Belongs to the sulfur carrier protein TusA family
HV340_RS12385	COG3047	cAMP biosynthetic process
HV340_RS12390	COG0727	PFAM Uncharacterised protein family (UPF0153)
HV340_RS12415	COG2350	Protein conserved in bacteria
HV340_RS12420	COG1280	lysine exporter protein (LysE YggA)
HV340_RS12440	COG3099	Belongs to the UPF0263 family
HV340_RS12445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV340_RS12450	COG4608	Belongs to the ABC transporter superfamily
HV340_RS12455	COG0444	Belongs to the ABC transporter superfamily
HV340_RS12465	COG0601	transmembrane transport
HV340_RS12475	COG2095	MarC family integral membrane protein
HV340_RS12480	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS12480	COG1454	alcohol dehydrogenase
HV340_RS12485	COG1435	thymidine kinase activity
HV340_RS12495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV340_RS12500	COG0745	RESPONSE REGULATOR receiver
HV340_RS12505	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV340_RS12510	COG3012	SEC-C Motif Domain Protein
HV340_RS12515	COG0788	formyltetrahydrofolate deformylase activity
HV340_RS12530	COG1522	sequence-specific DNA binding
HV340_RS12535	COG0697	spore germination
HV340_RS12540	COG2181	nitrate reductase activity
HV340_RS12545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV340_RS12550	COG1140	nitrate reductase beta subunit
HV340_RS12555	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV340_RS12560	COG2223	nitrite transmembrane transporter activity
HV340_RS12565	COG3850	Histidine kinase
HV340_RS12570	COG2197	response regulator
HV340_RS12575	COG4932	domain protein
HV340_RS12580	COG0243	molybdopterin cofactor binding
HV340_RS12585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV340_RS12585	COG2146	nitrite reductase [NAD(P)H] activity
HV340_RS12590	COG1116	anion transmembrane transporter activity
HV340_RS12600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV340_RS12605	COG3707	response regulator
HV340_RS12610	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV340_RS12615	COG0840	transmembrane signaling receptor activity
HV340_RS12625	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV340_RS12630	COG4572	Cation transport regulator
HV340_RS12635	COG0387	Pfam Sodium calcium exchanger
HV340_RS12655	COG2890	protein-(glutamine-N5) methyltransferase activity
HV340_RS12665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HV340_RS12670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HV340_RS12675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HV340_RS12685	COG0659	secondary active sulfate transmembrane transporter activity
HV340_RS12700	COG0193	aminoacyl-tRNA hydrolase activity
HV340_RS12705	COG0012	GTP binding
HV340_RS12725	COG3501	Rhs element vgr protein
HV340_RS12740	COG1397	ADP-ribosylglycohydrolase
HV340_RS12745	COG4104	PAAR repeat-containing protein
HV340_RS12755	COG3501	Rhs element vgr protein
HV340_RS12775	COG0515	serine threonine protein kinase
HV340_RS12895	COG0243	molybdopterin cofactor binding
HV340_RS12900	COG0583	DNA-binding transcription factor activity
HV340_RS12915	COG4977	sequence-specific DNA binding
HV340_RS12925	COG2814	Major facilitator Superfamily
HV340_RS12940	COG4774	siderophore transport
HV340_RS12955	COG0741	lytic transglycosylase activity
HV340_RS12960	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV340_RS12965	COG3263	regulation of cellular component size
HV340_RS12970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV340_RS12975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV340_RS12980	COG2719	SpoVR family
HV340_RS12985	COG2186	Transcriptional regulator
HV340_RS13000	COG2983	Belongs to the UPF0260 family
HV340_RS13005	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV340_RS13010	COG3100	YcgL domain-containing protein
HV340_RS13015	COG0850	regulation of cytokinetic process
HV340_RS13020	COG2894	cell division
HV340_RS13025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HV340_RS13030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV340_RS13040	COG3065	identical protein binding
HV340_RS13045	COG1214	PFAM Peptidase M22, glycoprotease
HV340_RS13050	COG1199	ATP-dependent helicase activity
HV340_RS13055	COG0251	oxidation-reduction process
HV340_RS13065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV340_RS13070	COG0494	nUDIX hydrolase
HV340_RS13075	COG1760	l-serine dehydratase
HV340_RS13085	COG1253	flavin adenine dinucleotide binding
HV340_RS13090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS13090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS13095	COG3715	PTS system
HV340_RS13100	COG3716	PTS system mannose fructose sorbose family IID component
HV340_RS13105	COG4811	Protein of unknown function (DUF986)
HV340_RS13110	COG1971	Probably functions as a manganese efflux pump
HV340_RS13115	COG2226	methyltransferase
HV340_RS13120	COG0768	penicillin binding
HV340_RS13155	COG1414	Transcriptional regulator
HV340_RS13160	COG2814	Major facilitator Superfamily
HV340_RS13165	COG0501	Belongs to the peptidase M48B family
HV340_RS13180	COG1956	GAF domain-containing protein
HV340_RS13185	COG2995	paraquat-inducible protein a
HV340_RS13190	COG3008	intermembrane lipid transfer
HV340_RS13195	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HV340_RS13195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HV340_RS13210	COG2990	Protein conserved in bacteria
HV340_RS13220	COG1276	copper resistance
HV340_RS13225	COG2372	response to copper ion
HV340_RS13235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV340_RS13240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV340_RS13245	COG1770	oligopeptidase
HV340_RS13250	COG2979	Protein of unknown function (DUF533)
HV340_RS13260	COG0800	Aldolase
HV340_RS13265	COG0129	dihydroxy-acid dehydratase activity
HV340_RS13270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV340_RS13275	COG1737	Transcriptional regulator
HV340_RS13285	COG1560	Kdo2-lipid A biosynthetic process
HV340_RS13290	COG0739	heme binding
HV340_RS13295	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV340_RS13305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV340_RS13310	COG2255	four-way junction helicase activity
HV340_RS13315	COG0632	four-way junction helicase activity
HV340_RS13330	COG0494	nUDIX hydrolase
HV340_RS13340	COG1335	isochorismatase
HV340_RS13345	COG1801	Protein of unknown function DUF72
HV340_RS13350	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV340_RS13355	COG2226	methyltransferase
HV340_RS13360	COG0500	methyltransferase
HV340_RS13365	COG3142	Participates in the control of copper homeostasis
HV340_RS13370	COG3102	Protein conserved in bacteria
HV340_RS13375	COG0018	arginyl-trna synthetase
HV340_RS13380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV340_RS13410	COG0745	RESPONSE REGULATOR receiver
HV340_RS13425	COG0840	transmembrane signaling receptor activity
HV340_RS13460	COG1301	dicarboxylic acid transport
HV340_RS13500	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HV340_RS13510	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS13520	COG1879	ABC-type sugar transport system periplasmic component
HV340_RS13530	COG1528	Iron-storage protein
HV340_RS13535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV340_RS13555	COG3437	response regulator, receiver
HV340_RS13555	COG0784	Response regulator, receiver
HV340_RS13565	COG1528	Iron-storage protein
HV340_RS13575	COG0814	amino acid
HV340_RS13580	COG3012	SEC-C Motif Domain Protein
HV340_RS13580	COG3318	Belongs to the UPF0149 family
HV340_RS13615	COG1278	Cold shock
HV340_RS13625	COG1349	DNA-binding transcription factor activity
HV340_RS13660	COG2197	response regulator
HV340_RS13670	COG2197	response regulator
HV340_RS13725	COG0366	Alpha amylase catalytic
HV340_RS13735	COG1677	Flagellar hook-basal body complex protein FliE
HV340_RS13745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HV340_RS13755	COG1157	protein secretion by the type III secretion system
HV340_RS13795	COG1987	bacterial-type flagellum assembly
HV340_RS13805	COG2197	response regulator
HV340_RS13830	COG5475	Uncharacterized small protein (DUF2158)
HV340_RS13835	COG2354	Protein conserved in bacteria
HV340_RS13840	COG0697	spore germination
HV340_RS13845	COG3727	T/G mismatch-specific endonuclease activity
HV340_RS13850	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV340_RS13855	COG1418	mRNA catabolic process
HV340_RS13860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV340_RS13870	COG3290	protein histidine kinase activity
HV340_RS13875	COG4565	transcriptional regulatory protein
HV340_RS13895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV340_RS13895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV340_RS13920	COG0583	DNA-binding transcription factor activity
HV340_RS13925	COG0835	chemotaxis
HV340_RS13930	COG2198	Histidine kinase
HV340_RS13930	COG0643	Histidine kinase
HV340_RS13955	COG1191	sigma factor activity
HV340_RS13960	COG0840	transmembrane signaling receptor activity
HV340_RS13965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HV340_RS13975	COG1705	Flagellar rod assembly protein muramidase FlgJ
HV340_RS13975	COG3951	Flagellar rod assembly protein muramidase FlgJ
HV340_RS13980	COG1706	bacterial-type flagellum-dependent cell motility
HV340_RS13985	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HV340_RS13990	COG4786	Flagellar basal body rod
HV340_RS14015	COG1815	bacterial-type flagellum-dependent cell motility
HV340_RS14070	COG0840	transmembrane signaling receptor activity
HV340_RS14125	COG1580	Controls the rotational direction of flagella during chemotaxis
HV340_RS14140	COG1157	protein secretion by the type III secretion system
HV340_RS14145	COG1317	bacterial-type flagellum organization
HV340_RS14160	COG1677	Flagellar hook-basal body complex protein FliE
HV340_RS14165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HV340_RS14170	COG2201	protein-glutamate methylesterase activity
HV340_RS14175	COG0745	RESPONSE REGULATOR receiver
HV340_RS14205	COG0500	methyltransferase
HV340_RS14260	COG0582	viral genome integration into host DNA
HV340_RS14295	COG1376	ErfK ybiS ycfS ynhG family protein
HV340_RS14300	COG0477	Major facilitator Superfamily
HV340_RS14305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV340_RS14310	COG0006	proline dipeptidase activity
HV340_RS14320	COG0534	Mate efflux family protein
HV340_RS14340	COG1289	transmembrane transporter activity
HV340_RS14345	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HV340_RS14545	COG0582	viral genome integration into host DNA
HV340_RS14550	COG2925	Exonuclease
HV340_RS14555	COG0531	amino acid
HV340_RS14565	COG0583	DNA-binding transcription factor activity
HV340_RS14570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV340_RS14580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HV340_RS14590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV340_RS14595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV340_RS14595	COG0131	Imidazoleglycerol-phosphate dehydratase
HV340_RS14600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV340_RS14605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HV340_RS14610	COG0107	imidazoleglycerol-phosphate synthase activity
HV340_RS14640	COG1088	dTDP-glucose 4,6-dehydratase activity
HV340_RS14665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HV340_RS14665	COG1215	transferase activity, transferring glycosyl groups
HV340_RS14685	COG2089	acid synthase
HV340_RS14695	COG1083	cytidylyl-transferase
HV340_RS14700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV340_RS14705	COG1086	Polysaccharide biosynthesis protein
HV340_RS14720	COG0438	transferase activity, transferring glycosyl groups
HV340_RS14725	COG2327	Polysaccharide pyruvyl transferase
HV340_RS14730	COG2244	polysaccharide biosynthetic process
HV340_RS14735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV340_RS14740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HV340_RS14750	COG0297	glycogen (starch) synthase activity
HV340_RS14755	COG1051	belongs to the nudix hydrolase family
HV340_RS14760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV340_RS14765	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HV340_RS14770	COG0110	maltose O-acetyltransferase activity
HV340_RS14775	COG1216	Glycosyl transferase, family 2
HV340_RS14785	COG0438	transferase activity, transferring glycosyl groups
HV340_RS14790	COG1045	serine acetyltransferase
HV340_RS14795	COG0463	Glycosyl transferase, family 2
HV340_RS14800	COG0489	protein tyrosine kinase activity
HV340_RS14800	COG3206	protein involved in exopolysaccharide biosynthesis
HV340_RS14815	COG1253	flavin adenine dinucleotide binding
HV340_RS14820	COG2982	Protein involved in outer membrane biogenesis
HV340_RS14825	COG0717	Belongs to the dCTP deaminase family
HV340_RS14835	COG3447	MASE1 domain protein
HV340_RS14835	COG5001	Diguanylate cyclase
HV340_RS14835	COG5002	protein histidine kinase activity
HV340_RS14840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV340_RS14845	COG0443	Heat shock 70 kDa protein
HV340_RS14850	COG2200	EAL domain
HV340_RS14850	COG2771	luxR family
HV340_RS14890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS14895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV340_RS14900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV340_RS14905	COG0477	Major facilitator Superfamily
HV340_RS14910	COG2205	protein histidine kinase activity
HV340_RS14915	COG0745	RESPONSE REGULATOR receiver
HV340_RS14920	COG3422	double-strand break repair
HV340_RS14930	COG1597	lipid kinase activity
HV340_RS14935	COG1830	Aldolase
HV340_RS14940	COG2211	Major facilitator Superfamily
HV340_RS14945	COG1397	ADP-ribosylglycohydrolase
HV340_RS14950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV340_RS14955	COG2188	Transcriptional regulator
HV340_RS14960	COG0351	phosphomethylpyrimidine kinase
HV340_RS14965	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HV340_RS14970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV340_RS14975	COG0076	glutamate decarboxylase activity
HV340_RS14980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV340_RS14985	COG0583	DNA-binding transcription factor activity
HV340_RS14995	COG2252	PERMEase
HV340_RS15000	COG0489	protein tyrosine kinase activity
HV340_RS15000	COG3206	protein involved in exopolysaccharide biosynthesis
HV340_RS15005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HV340_RS15010	COG1596	polysaccharide export
HV340_RS15015	COG5455	response to cobalt ion
HV340_RS15025	COG0489	protein tyrosine kinase activity
HV340_RS15035	COG4807	Protein conserved in bacteria
HV340_RS15045	COG3275	phosphorelay sensor kinase activity
HV340_RS15050	COG0789	Transcriptional regulator
HV340_RS15060	COG1174	glycine betaine transport
HV340_RS15065	COG1125	glycine betaine transport
HV340_RS15070	COG1174	glycine betaine transport
HV340_RS15075	COG1732	Glycine betaine
HV340_RS15080	COG1472	Belongs to the glycosyl hydrolase 3 family
HV340_RS15085	COG0277	FAD linked oxidase domain protein
HV340_RS15095	COG1686	Belongs to the peptidase S11 family
HV340_RS15105	COG0586	Pfam SNARE associated Golgi protein
HV340_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS15115	COG1538	Outer membrane efflux protein
HV340_RS15120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV340_RS15130	COG1346	cytolysis
HV340_RS15135	COG0295	cytidine deaminase activity
HV340_RS15140	COG2949	membrane
HV340_RS15145	COG0174	glutamine synthetase
HV340_RS15155	COG1129	ABC transporter
HV340_RS15170	COG2311	Membrane
HV340_RS15175	COG0302	gtp cyclohydrolase
HV340_RS15180	COG0477	Major facilitator Superfamily
HV340_RS15185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HV340_RS15190	COG4771	TonB-dependent receptor
HV340_RS15195	COG0833	amino acid
HV340_RS15200	COG0583	DNA-binding transcription factor activity
HV340_RS15205	COG2855	membrane
HV340_RS15210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HV340_RS15220	COG1105	Belongs to the carbohydrate kinase PfkB family
HV340_RS15240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HV340_RS15245	COG1312	Catalyzes the dehydration of D-mannonate
HV340_RS15250	COG0246	Mannitol dehydrogenase
HV340_RS15255	COG0523	cobalamin synthesis protein
HV340_RS15260	COG0671	phosphoesterase, PA-phosphatase related
HV340_RS15265	COG0791	NLP P60 protein
HV340_RS15270	COG2200	EAL domain
HV340_RS15275	COG4166	transmembrane transport
HV340_RS15280	COG4174	ABC transporter (Permease)
HV340_RS15285	COG4239	(ABC) transporter, permease
HV340_RS15290	COG4172	Belongs to the ABC transporter superfamily
HV340_RS15300	COG2814	Major facilitator Superfamily
HV340_RS15305	COG1187	pseudouridine synthase activity
HV340_RS15310	COG1061	Type III restriction enzyme res subunit
HV340_RS15320	COG3081	Nucleoid-associated protein
HV340_RS15325	COG3082	Protein of unknown function (DUF1414)
HV340_RS15365	COG3182	Iron-regulated membrane protein
HV340_RS15375	COG0579	oxidoreductase
HV340_RS15380	COG0659	secondary active sulfate transmembrane transporter activity
HV340_RS15385	COG2239	Acts as a magnesium transporter
HV340_RS15390	COG4615	Cyclic peptide transporter
HV340_RS15395	COG3145	DNA-N1-methyladenine dioxygenase activity
HV340_RS15400	COG2169	Transcriptional regulator
HV340_RS15400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV340_RS15415	COG2198	Histidine kinase
HV340_RS15415	COG0642	Histidine kinase
HV340_RS15420	COG2197	response regulator
HV340_RS15425	COG0784	Response regulator, receiver
HV340_RS15425	COG2205	protein histidine kinase activity
HV340_RS15435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV340_RS15440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV340_RS15445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV340_RS15450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV340_RS15455	COG0584	glycerophosphoryl diester phosphodiesterase
HV340_RS15460	COG2271	Major facilitator Superfamily
HV340_RS15465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV340_RS15470	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HV340_RS15475	COG0247	lactate metabolic process
HV340_RS15490	COG2205	protein histidine kinase activity
HV340_RS15520	COG1441	menaquinone biosynthetic process
HV340_RS15530	COG0596	Alpha beta hydrolase
HV340_RS15535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HV340_RS15540	COG1169	isochorismate synthase
HV340_RS15545	COG4575	ribosome binding
HV340_RS15550	COG2153	protein acetylation
HV340_RS15555	COG1234	tRNA 3'-trailer cleavage
HV340_RS15560	COG0835	chemotaxis
HV340_RS15560	COG0784	Response regulator, receiver
HV340_RS15565	COG1007	ATP synthesis coupled electron transport
HV340_RS15570	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV340_RS15575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV340_RS15580	COG0713	ATP synthesis coupled electron transport
HV340_RS15585	COG0839	Belongs to the complex I subunit 6 family
HV340_RS15595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HV340_RS15625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV340_RS15630	COG0583	DNA-binding transcription factor activity
HV340_RS15635	COG0436	Aminotransferase
HV340_RS15645	COG0490	domain, Protein
HV340_RS15645	COG0471	metal ion transport
HV340_RS15650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV340_RS15675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV340_RS15680	COG3959	Transketolase, thiamine diphosphate binding domain
HV340_RS15685	COG3037	sugar-specific permease SgaT UlaA
HV340_RS15695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS15700	COG1609	Transcriptional regulator
HV340_RS15710	COG0622	Phosphoesterase
HV340_RS15715	COG0625	glutathione transferase activity
HV340_RS15720	COG0625	glutathione transferase activity
HV340_RS15725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV340_RS15730	COG1090	epimerase
HV340_RS15740	COG4598	ABC transporter
HV340_RS15745	COG4160	amino acid transport
HV340_RS15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS15765	COG0163	prenyltransferase activity
HV340_RS15770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV340_RS15775	COG1286	toxin biosynthetic process
HV340_RS15780	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV340_RS15785	COG0285	dihydrofolate synthase activity
HV340_RS15795	COG0586	Pfam SNARE associated Golgi protein
HV340_RS15800	COG0101	tRNA pseudouridine synthase activity
HV340_RS15805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV340_RS15810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV340_RS15825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV340_RS15830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HV340_RS15830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV340_RS15840	COG3101	peptidyl-lysine hydroxylation
HV340_RS15845	COG0730	response to heat
HV340_RS15855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HV340_RS15865	COG2840	Smr protein MutS2
HV340_RS15870	COG2062	phosphohistidine phosphatase, SixA
HV340_RS15875	COG1024	Enoyl-CoA hydratase
HV340_RS15875	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV340_RS15885	COG3691	Protein conserved in bacteria
HV340_RS15890	COG2067	long-chain fatty acid transport protein
HV340_RS15900	COG2116	formate transmembrane transporter activity
HV340_RS15920	COG1560	Kdo2-lipid A biosynthetic process
HV340_RS15930	COG0436	Aminotransferase
HV340_RS15935	COG3275	phosphorelay sensor kinase activity
HV340_RS15940	COG3279	Response regulator of the LytR AlgR family
HV340_RS15945	COG0837	glucose binding
HV340_RS15955	COG3961	Belongs to the TPP enzyme family
HV340_RS15960	COG0667	Aldo Keto reductase
HV340_RS15970	COG1914	H( )-stimulated, divalent metal cation uptake system
HV340_RS15975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV340_RS15980	COG2200	EAL domain
HV340_RS15980	COG2199	diguanylate cyclase activity
HV340_RS15995	COG3415	Transposase
HV340_RS16000	COG3415	Transposase
HV340_RS16005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HV340_RS16035	COG0583	DNA-binding transcription factor activity
HV340_RS16040	COG2211	Major facilitator Superfamily
HV340_RS16045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HV340_RS16055	COG0583	DNA-binding transcription factor activity
HV340_RS16060	COG0385	Bile acid
HV340_RS16065	COG3530	Putative quorum-sensing-regulated virulence factor
HV340_RS16070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HV340_RS16075	COG3115	cell septum assembly
HV340_RS16090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS16115	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV340_RS16120	COG4208	sulfate ABC transporter
HV340_RS16125	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV340_RS16130	COG4150	thiosulfate binding
HV340_RS16135	COG2837	iron assimilation
HV340_RS16155	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV340_RS16160	COG0408	coproporphyrinogen oxidase activity
HV340_RS16175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV340_RS16180	COG5342	invasion associated locus B
HV340_RS16185	COG0494	nUDIX hydrolase
HV340_RS16190	COG0493	'glutamate synthase
HV340_RS16190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV340_RS16195	COG3850	Histidine kinase
HV340_RS16210	COG1393	Belongs to the ArsC family
HV340_RS16215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV340_RS16225	COG0400	carboxylic ester hydrolase activity
HV340_RS16230	COG1444	tRNA N-acetyltransferase activity
HV340_RS16235	COG2321	neutral zinc metallopeptidase
HV340_RS16245	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV340_RS16255	COG2716	regulation of RNA biosynthetic process
HV340_RS16260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV340_RS16265	COG0628	permease
HV340_RS16270	COG4783	chaperone-mediated protein folding
HV340_RS16275	COG1393	Belongs to the ArsC family
HV340_RS16290	COG1446	asparaginase
HV340_RS16295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HV340_RS16305	COG2233	PERMEase
HV340_RS16310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HV340_RS16315	COG2723	6-phospho-beta-galactosidase activity
HV340_RS16325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV340_RS16340	COG2200	EAL domain
HV340_RS16375	COG2814	Major facilitator Superfamily
HV340_RS16380	COG3718	enzyme involved in inositol metabolism
HV340_RS16395	COG0673	inositol 2-dehydrogenase activity
HV340_RS16400	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS16410	COG1879	ABC-type sugar transport system periplasmic component
HV340_RS16415	COG0673	inositol 2-dehydrogenase activity
HV340_RS16420	COG3962	Belongs to the TPP enzyme family
HV340_RS16440	COG0516	GMP reductase activity
HV340_RS16440	COG0517	IMP dehydrogenase activity
HV340_RS16445	COG1570	exodeoxyribonuclease VII activity
HV340_RS16460	COG1645	bacterial-type flagellum-dependent swarming motility
HV340_RS16470	COG3104	oligopeptide transport
HV340_RS16475	COG1160	GTP binding
HV340_RS16485	COG2976	Protein conserved in bacteria
HV340_RS16490	COG0124	histidyl-tRNA synthetase
HV340_RS16495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HV340_RS16505	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HV340_RS16515	COG4953	penicillin-binding protein 1C
HV340_RS16520	COG2373	Large extracellular alpha-helical protein
HV340_RS16525	COG2190	(PTS) system
HV340_RS16525	COG1263	PTS System
HV340_RS16525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS16535	COG2897	thiosulfate sulfurtransferase activity
HV340_RS16540	COG1737	Transcriptional regulator
HV340_RS16550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HV340_RS16555	COG2975	iron-sulfur cluster assembly
HV340_RS16560	COG0633	Ferredoxin
HV340_RS16565	COG0443	Heat shock 70 kDa protein
HV340_RS16575	COG0316	Belongs to the HesB IscA family
HV340_RS16580	COG0822	iron-sulfur transferase activity
HV340_RS16585	COG1104	cysteine desulfurase activity
HV340_RS16600	COG0483	inositol monophosphate 1-phosphatase activity
HV340_RS16605	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV340_RS16615	COG3711	transcriptional antiterminator
HV340_RS16620	COG2814	Major facilitator Superfamily
HV340_RS16625	COG2259	Doxx family
HV340_RS16630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HV340_RS16635	COG1017	nitric oxide dioxygenase activity
HV340_RS16635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV340_RS16640	COG0347	Belongs to the P(II) protein family
HV340_RS16645	COG2204	response regulator
HV340_RS16650	COG3170	Tfp pilus assembly protein FimV
HV340_RS16655	COG2205	protein histidine kinase activity
HV340_RS16660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HV340_RS16660	COG0047	phosphoribosylformylglycinamidine synthase activity
HV340_RS16665	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HV340_RS16675	COG0560	Phosphoserine phosphatase
HV340_RS16680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS16680	COG1263	PTS System
HV340_RS16685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV340_RS16690	COG1737	Transcriptional regulator
HV340_RS16695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV340_RS16705	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV340_RS16710	COG1381	Involved in DNA repair and RecF pathway recombination
HV340_RS16715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HV340_RS16725	COG0681	Belongs to the peptidase S26 family
HV340_RS16730	COG0481	GTPase activity
HV340_RS16735	COG3086	response to oxidative stress
HV340_RS16745	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HV340_RS16760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV340_RS16765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HV340_RS16770	COG0513	Belongs to the DEAD box helicase family
HV340_RS16775	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
HV340_RS16785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV340_RS16790	COG3118	belongs to the thioredoxin family
HV340_RS16805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV340_RS16810	COG5544	Lipoprotein
HV340_RS16815	COG0477	Major facilitator Superfamily
HV340_RS16840	COG0542	response to heat
HV340_RS16855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV340_RS16860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV340_RS16870	COG0077	Prephenate dehydratase
HV340_RS16870	COG1605	Chorismate mutase
HV340_RS16880	COG0287	Prephenate dehydrogenase
HV340_RS16880	COG1605	Chorismate mutase
HV340_RS16900	COG2199	diguanylate cyclase activity
HV340_RS16905	COG2885	chlorophyll binding
HV340_RS16925	COG0336	Belongs to the RNA methyltransferase TrmD family
HV340_RS16930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HV340_RS16940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV340_RS16945	COG4137	Cytochrome C assembly protein
HV340_RS16950	COG4536	flavin adenine dinucleotide binding
HV340_RS16955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HV340_RS16960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HV340_RS16965	COG0497	DNA recombination
HV340_RS16980	COG2867	negative regulation of translational initiation
HV340_RS17005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV340_RS17040	COG3772	lysozyme
HV340_RS17080	COG4197	protein conserved in bacteria, prophage-related
HV340_RS17120	COG0582	viral genome integration into host DNA
HV340_RS17125	COG0582	viral genome integration into host DNA
HV340_RS17135	COG1475	DNA binding
HV340_RS17150	COG0210	DNA helicase
HV340_RS17255	COG1715	Restriction endonuclease
HV340_RS17255	COG1787	Restriction endonuclease
HV340_RS17365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS17370	COG1051	belongs to the nudix hydrolase family
HV340_RS17375	COG2207	Transcriptional regulator
HV340_RS17390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV340_RS17405	COG2226	methyltransferase
HV340_RS17410	COG3958	Transketolase
HV340_RS17415	COG3959	Transketolase, thiamine diphosphate binding domain
HV340_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS17425	COG2271	Major facilitator Superfamily
HV340_RS17430	COG0583	DNA-binding transcription factor activity
HV340_RS17435	COG0402	S-adenosylhomocysteine deaminase activity
HV340_RS17440	COG0549	Belongs to the carbamate kinase family
HV340_RS17450	COG1304	FMN binding
HV340_RS17455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV340_RS17460	COG0666	response to abiotic stimulus
HV340_RS17465	COG0583	DNA-binding transcription factor activity
HV340_RS17470	COG0401	homolog of Blt101
HV340_RS17475	COG0640	Transcriptional regulator
HV340_RS17480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV340_RS17505	COG4575	ribosome binding
HV340_RS17515	COG1780	Probably involved in ribonucleotide reductase function
HV340_RS17535	COG4176	ABC-type proline glycine betaine transport system permease component
HV340_RS17545	COG2814	Major facilitator Superfamily
HV340_RS17550	COG1846	Transcriptional regulator
HV340_RS17555	COG1566	PFAM secretion protein HlyD family protein
HV340_RS17560	COG2814	Major facilitator Superfamily
HV340_RS17565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV340_RS17580	COG2918	glutathione biosynthetic process
HV340_RS17585	COG1238	metal cluster binding
HV340_RS17590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV340_RS17620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV340_RS17625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV340_RS17640	COG1546	Belongs to the CinA family
HV340_RS17645	COG0803	Belongs to the bacterial solute-binding protein 9 family
HV340_RS17650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV340_RS17660	COG2951	lytic endotransglycosylase activity
HV340_RS17665	COG3730	PTS system glucitol sorbitol-specific
HV340_RS17670	COG3732	PTS system glucitol sorbitol-specific
HV340_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS17685	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS17690	COG1349	DNA-binding transcription factor activity
HV340_RS17700	COG3604	Transcriptional regulator
HV340_RS17705	COG1773	rubredoxin
HV340_RS17705	COG0426	domain, Protein
HV340_RS17710	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV340_RS17715	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV340_RS17720	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV340_RS17725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV340_RS17730	COG1609	Transcriptional regulator
HV340_RS17735	COG1263	PTS System
HV340_RS17735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS17740	COG2723	6-phospho-beta-galactosidase activity
HV340_RS17745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV340_RS17755	COG3260	NADH ubiquinone oxidoreductase 20
HV340_RS17760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV340_RS17765	COG3261	NADH dehydrogenase
HV340_RS17765	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV340_RS17770	COG0650	Formate hydrogenlyase subunit 4
HV340_RS17775	COG0651	ATP synthesis coupled electron transport
HV340_RS17780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV340_RS17795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV340_RS17800	COG0298	carbon dioxide binding
HV340_RS17805	COG0409	Hydrogenase expression formation protein
HV340_RS17810	COG0309	Hydrogenase expression formation protein (HypE)
HV340_RS17840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV340_RS17845	COG0163	prenyltransferase activity
HV340_RS17860	COG0477	Major facilitator Superfamily
HV340_RS17890	COG0585	pseudouridine synthase activity
HV340_RS17900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HV340_RS17905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HV340_RS17915	COG0529	Catalyzes the synthesis of activated sulfate
HV340_RS17935	COG2234	aminopeptidase activity
HV340_RS17945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV340_RS17950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HV340_RS17955	COG0720	synthase
HV340_RS17960	COG0602	queuosine metabolic process
HV340_RS17965	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HV340_RS17970	COG1263	PTS System
HV340_RS17970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS17970	COG2190	(PTS) system
HV340_RS17975	COG1737	Transcriptional regulator
HV340_RS17995	COG3956	TIGRFAM MazG family protein
HV340_RS18000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV340_RS18005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV340_RS18010	COG3850	Histidine kinase
HV340_RS18010	COG3437	response regulator, receiver
HV340_RS18010	COG2205	protein histidine kinase activity
HV340_RS18010	COG4999	Histidine kinase
HV340_RS18015	COG1929	Belongs to the glycerate kinase type-1 family
HV340_RS18020	COG4948	Mandelate Racemase Muconate Lactonizing
HV340_RS18025	COG4948	Mandelate Racemase Muconate Lactonizing
HV340_RS18030	COG2271	Major facilitator Superfamily
HV340_RS18035	COG0716	FMN binding
HV340_RS18040	COG0564	pseudouridine synthase activity
HV340_RS18045	COG3098	single-species biofilm formation
HV340_RS18060	COG1611	Belongs to the LOG family
HV340_RS18065	COG0814	amino acid
HV340_RS18070	COG1760	l-serine dehydratase
HV340_RS18085	COG2363	Small membrane protein
HV340_RS18090	COG0583	DNA-binding transcription factor activity
HV340_RS18100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV340_RS18105	COG2166	iron-sulfur cluster assembly
HV340_RS18110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV340_RS18115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV340_RS18135	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV340_RS18140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV340_RS18140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV340_RS18145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV340_RS18150	COG1074	ATP-dependent DNA helicase activity
HV340_RS18160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV340_RS18165	COG4967	type IV pilus modification protein PilV
HV340_RS18175	COG4795	General secretion pathway protein
HV340_RS18180	COG2165	general secretion pathway protein
HV340_RS18185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HV340_RS18190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HV340_RS18200	COG0494	nUDIX hydrolase
HV340_RS18205	COG3066	DNA modification
HV340_RS18215	COG0667	Aldo Keto reductase
HV340_RS18220	COG0477	Major facilitator Superfamily
HV340_RS18225	COG0204	Acyl-transferase
HV340_RS18225	COG0318	PFAM AMP-dependent synthetase and ligase
HV340_RS18230	COG1609	Transcriptional regulator
HV340_RS18240	COG2186	Transcriptional regulator
HV340_RS18245	COG2723	6-phospho-beta-galactosidase activity
HV340_RS18250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS18255	COG1609	Transcriptional regulator
HV340_RS18265	COG0583	DNA-binding transcription factor activity
HV340_RS18270	COG1794	racemase activity, acting on amino acids and derivatives
HV340_RS18280	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HV340_RS18285	COG1175	transmembrane transport
HV340_RS18290	COG0395	ABC-type sugar transport system, permease component
HV340_RS18295	COG3842	ATPase activity
HV340_RS18305	COG2814	Major facilitator Superfamily
HV340_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS18320	COG0823	Involved in the tonB-independent uptake of proteins
HV340_RS18330	COG0183	Belongs to the thiolase family
HV340_RS18345	COG0814	amino acid
HV340_RS18360	COG2388	GCN5-related N-acetyl-transferase
HV340_RS18365	COG3592	Divergent 4Fe-4S mono-cluster
HV340_RS18385	COG4208	sulfate ABC transporter
HV340_RS18390	COG3842	ATPase activity
HV340_RS18400	COG2723	6-phospho-beta-galactosidase activity
HV340_RS18410	COG4580	involved in the transport of maltose and maltodextrins
HV340_RS18415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS18420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS18425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV340_RS18430	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV340_RS18435	COG1940	carbohydrate kinase activity
HV340_RS18440	COG1609	Transcriptional regulator
HV340_RS18455	COG4942	peptidase
HV340_RS18460	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HV340_RS18465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HV340_RS18475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV340_RS18485	COG4974	Belongs to the 'phage' integrase family
HV340_RS18500	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV340_RS18505	COG0354	folic acid binding
HV340_RS18510	COG1272	protein, Hemolysin III
HV340_RS18515	COG1737	Transcriptional regulator
HV340_RS18520	COG2723	6-phospho-beta-galactosidase activity
HV340_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS18530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HV340_RS18530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HV340_RS18540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HV340_RS18545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV340_RS18550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV340_RS18555	COG0006	proline dipeptidase activity
HV340_RS18565	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HV340_RS18575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV340_RS18580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV340_RS18590	COG0583	DNA-binding transcription factor activity
HV340_RS18595	COG2968	Membrane
HV340_RS18600	COG1279	arginine transmembrane transporter activity
HV340_RS18605	COG0668	transmembrane transport
HV340_RS18610	COG0191	fructose-bisphosphate aldolase activity
HV340_RS18620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV340_RS18625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV340_RS18630	COG0501	Belongs to the peptidase M48B family
HV340_RS18650	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HV340_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS18670	COG2814	Major facilitator Superfamily
HV340_RS18685	COG1414	Transcriptional regulator
HV340_RS18690	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS18705	COG2146	nitrite reductase [NAD(P)H] activity
HV340_RS18715	COG0010	Belongs to the arginase family
HV340_RS18720	COG1166	arginine decarboxylase activity
HV340_RS18745	COG2814	Major facilitator Superfamily
HV340_RS18750	COG3091	SprT-like family
HV340_RS18755	COG2356	endonuclease I
HV340_RS18760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV340_RS18780	COG2805	Type II/IV secretion system protein
HV340_RS18785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV340_RS18790	COG0762	integral membrane protein
HV340_RS18795	COG1872	DUF167
HV340_RS18805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV340_RS18810	COG2852	Protein conserved in bacteria
HV340_RS18820	COG3171	Protein conserved in bacteria
HV340_RS18830	COG1194	a g-specific adenine glycosylase
HV340_RS18840	COG0741	lytic transglycosylase activity
HV340_RS18845	COG2211	Major facilitator Superfamily
HV340_RS18850	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HV340_RS18870	COG3052	prosthetic group binding
HV340_RS18880	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV340_RS18885	COG3493	citrate carrier protein
HV340_RS18900	COG1982	Orn Lys Arg decarboxylase major
HV340_RS18905	COG1811	Na channel or pump
HV340_RS18920	COG0457	Tetratricopeptide repeat
HV340_RS18925	COG0726	polysaccharide deacetylase
HV340_RS18925	COG1649	PFAM Uncharacterised BCR, COG1649
HV340_RS18930	COG1215	transferase activity, transferring glycosyl groups
HV340_RS18940	COG0754	glutathionylspermidine amidase activity
HV340_RS18945	COG0625	glutathione transferase activity
HV340_RS18960	COG0667	Aldo Keto reductase
HV340_RS18965	COG2862	Uncharacterized protein family, UPF0114
HV340_RS18985	COG0848	biopolymer transport protein
HV340_RS18995	COG0626	cystathionine gamma-synthase activity
HV340_RS19000	COG0586	Pfam SNARE associated Golgi protein
HV340_RS19005	COG2207	Transcriptional regulator
HV340_RS19010	COG1979	alcohol dehydrogenase
HV340_RS19055	COG0604	alcohol dehydrogenase
HV340_RS19125	COG0697	spore germination
HV340_RS19130	COG1234	tRNA 3'-trailer cleavage
HV340_RS19140	COG1902	pentaerythritol trinitrate reductase activity
HV340_RS19145	COG0640	Transcriptional regulator
HV340_RS19185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HV340_RS19205	COG3111	PFAM Bacterial OB fold (BOF) protein
HV340_RS19220	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV340_RS19225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV340_RS19230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV340_RS19235	COG2211	Major facilitator Superfamily
HV340_RS19245	COG2207	Transcriptional regulator
HV340_RS19245	COG1917	Cupin 2, conserved barrel domain protein
HV340_RS19260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS19265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS19270	COG1120	ATPase activity
HV340_RS19275	COG4774	siderophore transport
HV340_RS19280	COG0187	DNA topoisomerase II activity
HV340_RS19285	COG3150	esterase
HV340_RS19290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV340_RS19295	COG3151	Protein conserved in bacteria
HV340_RS19300	COG0494	nUDIX hydrolase
HV340_RS19315	COG0754	glutathionylspermidine amidase activity
HV340_RS19320	COG3384	dioxygenase
HV340_RS19330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HV340_RS19340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HV340_RS19340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HV340_RS19350	COG3025	triphosphatase activity
HV340_RS19355	COG4991	sh3 domain protein
HV340_RS19360	COG0617	tRNA 3'-terminal CCA addition
HV340_RS19370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV340_RS19380	COG0477	Major facilitator Superfamily
HV340_RS19385	COG0829	nickel cation binding
HV340_RS19390	COG0831	urea catabolic process
HV340_RS19395	COG0832	Belongs to the urease beta subunit family
HV340_RS19400	COG0804	urea catabolic process
HV340_RS19405	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HV340_RS19415	COG0830	nickel cation binding
HV340_RS19420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV340_RS19430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV340_RS19435	COG0358	DNA primase activity
HV340_RS19445	COG3663	DNA glycosylase
HV340_RS19495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV340_RS19590	COG4695	Portal protein
HV340_RS19640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV340_RS19690	COG0582	viral genome integration into host DNA
HV340_RS19740	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV340_RS19805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV340_RS19830	COG2375	cellular response to nickel ion
HV340_RS19835	COG1695	Transcriptional regulator
HV340_RS19840	COG0840	transmembrane signaling receptor activity
HV340_RS19845	COG0840	transmembrane signaling receptor activity
HV340_RS19850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV340_RS19865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV340_RS19870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV340_RS19875	COG1830	Aldolase
HV340_RS19880	COG1879	ABC-type sugar transport system periplasmic component
HV340_RS19885	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS19890	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS19895	COG1129	ABC transporter
HV340_RS19900	COG2390	Transcriptional regulator
HV340_RS19905	COG1070	Carbohydrate kinase
HV340_RS19910	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV340_RS19910	COG1902	pentaerythritol trinitrate reductase activity
HV340_RS19920	COG1451	nucleotide metabolic process
HV340_RS19925	COG0673	inositol 2-dehydrogenase activity
HV340_RS19930	COG0861	Integral membrane protein TerC family
HV340_RS19940	COG2721	sulfolactate sulfo-lyase activity
HV340_RS19950	COG2271	Major facilitator Superfamily
HV340_RS19955	COG2186	Transcriptional regulator
HV340_RS19960	COG0586	Pfam SNARE associated Golgi protein
HV340_RS19970	COG1422	Protein of unknown function (DUF1090)
HV340_RS19975	COG4575	ribosome binding
HV340_RS19980	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV340_RS19990	COG2259	Doxx family
HV340_RS19995	COG0435	Glutathione S-transferase
HV340_RS20000	COG3152	Membrane
HV340_RS20005	COG0583	DNA-binding transcription factor activity
HV340_RS20010	COG1741	Belongs to the pirin family
HV340_RS20030	COG1882	Formate acetyltransferase
HV340_RS20035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HV340_RS20040	COG0814	amino acid
HV340_RS20045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV340_RS20050	COG0583	DNA-binding transcription factor activity
HV340_RS20065	COG1929	Belongs to the glycerate kinase type-1 family
HV340_RS20070	COG2084	Dehydrogenase
HV340_RS20080	COG2721	sulfolactate sulfo-lyase activity
HV340_RS20085	COG1349	DNA-binding transcription factor activity
HV340_RS20095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS20105	COG3716	PTS system mannose fructose sorbose family IID component
HV340_RS20110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS20115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV340_RS20120	COG2222	sugar isomerase
HV340_RS20125	COG0191	fructose-bisphosphate aldolase activity
HV340_RS20130	COG1263	PTS System
HV340_RS20130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV340_RS20135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV340_RS20145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV340_RS20150	COG3107	peptidoglycan biosynthetic process
HV340_RS20155	COG0792	nuclease activity
HV340_RS20160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HV340_RS20165	COG2823	Periplasmic or secreted lipoprotein
HV340_RS20170	COG0701	Predicted permease
HV340_RS20175	COG0702	epimerase
HV340_RS20180	COG0693	protein deglycase activity
HV340_RS20185	COG3787	Belongs to the UPF0306 family
HV340_RS20190	COG2827	Endonuclease containing a URI domain
HV340_RS20195	COG3153	acetyltransferase
HV340_RS20200	COG3154	lipid carrier protein
HV340_RS20205	COG0826	peptidase U32
HV340_RS20210	COG0826	peptidase U32
HV340_RS20215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV340_RS20220	COG0814	amino acid
HV340_RS20225	COG0513	Belongs to the DEAD box helicase family
HV340_RS20240	COG1185	polyribonucleotide nucleotidyltransferase activity
HV340_RS20245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HV340_RS20250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HV340_RS20255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HV340_RS20260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HV340_RS20280	COG0137	argininosuccinate synthase activity
HV340_RS20290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV340_RS20295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HV340_RS20300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV340_RS20310	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HV340_RS20315	COG1534	Rna-binding protein
HV340_RS20325	COG2027	D-alanyl-D-alanine carboxypeptidase
HV340_RS20330	COG0745	RESPONSE REGULATOR receiver
HV340_RS20335	COG0642	Histidine kinase
HV340_RS20340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HV340_RS20345	COG0697	spore germination
HV340_RS20355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HV340_RS20360	COG0142	geranyltranstransferase activity
HV340_RS20365	COG3423	Transcriptional regulator
HV340_RS20370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HV340_RS20375	COG5007	Belongs to the BolA IbaG family
HV340_RS20380	COG3113	response to antibiotic
HV340_RS20385	COG2854	intermembrane phospholipid transfer
HV340_RS20390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV340_RS20395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV340_RS20400	COG1127	ABC transporter
HV340_RS20405	COG0530	calcium, potassium:sodium antiporter activity
HV340_RS20415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV340_RS20420	COG3117	lipopolysaccharide transmembrane transporter activity
HV340_RS20425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV340_RS20430	COG1137	ATPase activity
HV340_RS20435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HV340_RS20455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV340_RS20465	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV340_RS20470	COG0784	Response regulator, receiver
HV340_RS20470	COG5002	protein histidine kinase activity
HV340_RS20470	COG2198	Histidine kinase
HV340_RS20475	COG0795	lipopolysaccharide-transporting ATPase activity
HV340_RS20480	COG0795	lipopolysaccharide-transporting ATPase activity
HV340_RS20485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HV340_RS20490	COG2927	DNA polymerase III (CHI subunit)
HV340_RS20505	COG1064	alcohol dehydrogenase
HV340_RS20515	COG0433	COG0433 Predicted ATPase
HV340_RS20520	COG1242	4 iron, 4 sulfur cluster binding
HV340_RS20525	COG0067	glutamate synthase
HV340_RS20525	COG0069	glutamate synthase activity
HV340_RS20525	COG0070	glutamate synthase
HV340_RS20530	COG0493	'glutamate synthase
HV340_RS20540	COG3188	usher protein
HV340_RS20545	COG3121	Chaperone
HV340_RS20550	COG3539	Fimbrial protein
HV340_RS20555	COG2969	positive regulation of protein catabolic process
HV340_RS20560	COG0625	glutathione transferase activity
HV340_RS20565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HV340_RS20575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV340_RS20580	COG3105	Protein conserved in bacteria
HV340_RS20585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV340_RS20590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV340_RS20595	COG0039	L-malate dehydrogenase activity
HV340_RS20615	COG2732	(Barnase) inhibitor
HV340_RS20620	COG1012	belongs to the aldehyde dehydrogenase family
HV340_RS20625	COG1289	transmembrane transporter activity
HV340_RS20640	COG0583	DNA-binding transcription factor activity
HV340_RS20645	COG3477	response to acidic pH
HV340_RS20650	COG0312	modulator of DNA gyrase
HV340_RS20655	COG3164	Protein of unknown function
HV340_RS20660	COG1530	ribonuclease E activity
HV340_RS20670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV340_RS20675	COG1792	Involved in formation and maintenance of cell shape
HV340_RS20680	COG1077	Cell shape determining protein MreB Mrl
HV340_RS20685	COG2200	EAL domain
HV340_RS20685	COG2199	diguanylate cyclase activity
HV340_RS20690	COG0604	alcohol dehydrogenase
HV340_RS20700	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HV340_RS20705	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HV340_RS20710	COG0511	ligase activity, forming carbon-carbon bonds
HV340_RS20715	COG0439	Biotin carboxylase
HV340_RS20720	COG3924	membrane
HV340_RS20725	COG4145	pantothenate transmembrane transporter activity
HV340_RS20760	COG1309	transcriptional regulator
HV340_RS20765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS20780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV340_RS20785	COG4597	amino acid ABC transporter
HV340_RS20790	COG0765	amino acid transport
HV340_RS20795	COG1126	abc transporter atp-binding protein
HV340_RS20830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV340_RS20840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV340_RS20845	COG0009	L-threonylcarbamoyladenylate synthase
HV340_RS20850	COG0551	DNA topoisomerase type I activity
HV340_RS20855	COG2922	Belongs to the Smg family
HV340_RS20860	COG0758	DNA mediated transformation
HV340_RS20865	COG0242	peptide deformylase activity
HV340_RS20870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HV340_RS20875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HV340_RS20875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HV340_RS20890	COG3036	rescue of stalled ribosome
HV340_RS20895	COG0789	Transcriptional regulator
HV340_RS20905	COG0203	ribosomal protein L17
HV340_RS20910	COG0202	RNA polymerase activity
HV340_RS20920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV340_RS20935	COG0201	protein transport
HV340_RS20945	COG1841	ribosomal large subunit assembly
HV340_RS20955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HV340_RS20960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HV340_RS20965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HV340_RS20995	COG0255	Belongs to the universal ribosomal protein uL29 family
HV340_RS21000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HV340_RS21040	COG0051	transcription antitermination factor activity, RNA binding
HV340_RS21080	COG2168	tRNA wobble position uridine thiolation
HV340_RS21085	COG2923	Belongs to the DsrF TusC family
HV340_RS21090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV340_RS21095	COG2964	Protein conserved in bacteria
HV340_RS21100	COG0545	Peptidyl-prolyl cis-trans isomerase
HV340_RS21105	COG2900	Belongs to the SlyX family
HV340_RS21110	COG1047	Peptidyl-prolyl cis-trans
HV340_RS21115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV340_RS21120	COG0475	glutathione-regulated potassium exporter activity
HV340_RS21120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV340_RS21125	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV340_RS21130	COG0488	(ABC) transporter
HV340_RS21140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV340_RS21150	COG0679	Auxin Efflux Carrier
HV340_RS21180	COG0429	hydrolase of the alpha beta-hydrolase fold
HV340_RS21185	COG3089	Belongs to the UPF0270 family
HV340_RS21190	COG3954	Phosphoribulokinase
HV340_RS21195	COG1765	OsmC-like protein
HV340_RS21205	COG1289	transmembrane transporter activity
HV340_RS21210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV340_RS21215	COG0512	Glutamine amidotransferase of anthranilate synthase
HV340_RS21235	COG0738	Major facilitator superfamily
HV340_RS21240	COG0402	S-adenosylhomocysteine deaminase activity
HV340_RS21245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV340_RS21255	COG1648	precorrin-2 dehydrogenase activity
HV340_RS21255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HV340_RS21265	COG0180	Tryptophanyl-tRNA synthetase
HV340_RS21275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV340_RS21280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV340_RS21285	COG3266	domain, Protein
HV340_RS21290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HV340_RS21295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV340_RS21300	COG4796	Type ii and iii secretion system protein
HV340_RS21325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV340_RS21330	COG0494	nUDIX hydrolase
HV340_RS21340	COG1011	Hydrolase
HV340_RS21345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV340_RS21350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HV340_RS21355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HV340_RS21365	COG0745	RESPONSE REGULATOR receiver
HV340_RS21370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV340_RS21375	COG2183	response to ionizing radiation
HV340_RS21380	COG1918	ferrous iron import across plasma membrane
HV340_RS21405	COG1040	competence protein
HV340_RS21420	COG1640	4-alpha-glucanotransferase
HV340_RS21425	COG0058	SHG alpha-glucan phosphorylase activity
HV340_RS21430	COG2909	trisaccharide binding
HV340_RS21435	COG1349	DNA-binding transcription factor activity
HV340_RS21440	COG0705	Rhomboid family
HV340_RS21445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV340_RS21450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV340_RS21455	COG0058	SHG alpha-glucan phosphorylase activity
HV340_RS21460	COG0297	glycogen (starch) synthase activity
HV340_RS21465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HV340_RS21470	COG1523	belongs to the glycosyl hydrolase 13 family
HV340_RS21475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HV340_RS21480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV340_RS21485	COG2095	MarC family integral membrane protein
HV340_RS21490	COG2610	gluconate transmembrane transporter activity
HV340_RS21495	COG3265	gluconokinase activity
HV340_RS21500	COG1609	Transcriptional regulator
HV340_RS21505	COG1741	Belongs to the pirin family
HV340_RS21510	COG0673	inositol 2-dehydrogenase activity
HV340_RS21515	COG1247	-acetyltransferase
HV340_RS21520	COG0405	Gamma-glutamyltransferase
HV340_RS21530	COG0584	glycerophosphoryl diester phosphodiesterase
HV340_RS21560	COG0411	ABC transporter
HV340_RS21565	COG4177	L-phenylalanine transmembrane transporter activity
HV340_RS21575	COG0683	leucine binding
HV340_RS21585	COG0683	leucine binding
HV340_RS21590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV340_RS21595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV340_RS21600	COG2177	Part of the ABC transporter FtsEX involved in
HV340_RS21605	COG2884	Cell division ATP-binding protein ftsE
HV340_RS21610	COG0552	protein localization to endoplasmic reticulum
HV340_RS21615	COG0742	ribosomal rna small subunit methyltransferase
HV340_RS21620	COG3776	membrane
HV340_RS21630	COG3714	YhhN family
HV340_RS21650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV340_RS21655	COG0425	Belongs to the sulfur carrier protein TusA family
HV340_RS21660	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV340_RS21670	COG0477	Major facilitator Superfamily
HV340_RS21675	COG0628	permease
HV340_RS21705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HV340_RS21715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV340_RS21715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV340_RS21725	COG1216	Glycosyl transferase, family 2
HV340_RS21750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV340_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS21765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV340_RS21770	COG2091	lysine biosynthetic process via aminoadipic acid
HV340_RS21810	COG3479	Phenolic acid decarboxylase
HV340_RS21815	COG0583	DNA-binding transcription factor activity
HV340_RS21820	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS21825	COG0791	NLP P60 protein
HV340_RS21850	COG1414	Transcriptional regulator
HV340_RS21855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HV340_RS21860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV340_RS21865	COG2081	HI0933 family
HV340_RS21870	COG0306	phosphate transporter
HV340_RS21880	COG0589	response to stress
HV340_RS21890	COG0339	signal peptide processing
HV340_RS21895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV340_RS21900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV340_RS21915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV340_RS21925	COG2197	response regulator
HV340_RS21930	COG1028	Short-chain dehydrogenase reductase Sdr
HV340_RS21935	COG0583	DNA-binding transcription factor activity
HV340_RS21940	COG1295	ribonuclease BN
HV340_RS21945	COG0477	Major facilitator Superfamily
HV340_RS21950	COG2982	Protein involved in outer membrane biogenesis
HV340_RS21955	COG2200	EAL domain
HV340_RS21965	COG0612	Peptidase, M16
HV340_RS21970	COG1301	dicarboxylic acid transport
HV340_RS21975	COG2200	EAL domain
HV340_RS21975	COG2199	diguanylate cyclase activity
HV340_RS21980	COG0457	Tetratricopeptide repeat
HV340_RS21980	COG3118	belongs to the thioredoxin family
HV340_RS21985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HV340_RS21990	COG1215	transferase activity, transferring glycosyl groups
HV340_RS22020	COG2194	sulfuric ester hydrolase activity
HV340_RS22035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV340_RS22065	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HV340_RS22075	COG1739	Uncharacterized protein family UPF0029
HV340_RS22080	COG0006	proline dipeptidase activity
HV340_RS22085	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV340_RS22085	COG1024	Enoyl-CoA hydratase
HV340_RS22090	COG0183	Belongs to the thiolase family
HV340_RS22100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV340_RS22110	COG0084	hydrolase, TatD family'
HV340_RS22115	COG0805	protein transport
HV340_RS22125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV340_RS22130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HV340_RS22135	COG3165	ubiquinone biosynthetic process from chorismate
HV340_RS22140	COG2226	methyltransferase
HV340_RS22145	COG1322	Protein conserved in bacteria
HV340_RS22155	COG0412	Dienelactone hydrolase
HV340_RS22165	COG0583	DNA-binding transcription factor activity
HV340_RS22170	COG0697	spore germination
HV340_RS22175	COG0561	phosphatase activity
HV340_RS22180	COG2267	carboxylic ester hydrolase activity
HV340_RS22185	COG1280	lysine exporter protein (LysE YggA)
HV340_RS22190	COG1280	lysine exporter protein (LysE YggA)
HV340_RS22200	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HV340_RS22225	COG1011	Hydrolase
HV340_RS22260	COG0181	hydroxymethylbilane synthase activity
HV340_RS22270	COG2959	enzyme of heme biosynthesis
HV340_RS22275	COG3071	HemY protein
HV340_RS22310	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HV340_RS22330	COG2244	polysaccharide biosynthetic process
HV340_RS22335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV340_RS22340	COG0456	acetyltransferase
HV340_RS22345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV340_RS22350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV340_RS22355	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HV340_RS22360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV340_RS22365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV340_RS22370	COG3118	belongs to the thioredoxin family
HV340_RS22380	COG0248	Ppx GppA phosphatase
HV340_RS22390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV340_RS22400	COG0583	DNA-binding transcription factor activity
HV340_RS22405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV340_RS22415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV340_RS22420	COG3978	acetolactate synthase activity
HV340_RS22445	COG3085	chromosome segregation
HV340_RS22495	COG4206	TonB-dependent receptor
HV340_RS22500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV340_RS22520	COG0583	DNA-binding transcription factor activity
HV340_RS22525	COG0165	Argininosuccinate lyase
HV340_RS22535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV340_RS22540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV340_RS22545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HV340_RS22550	COG2207	Transcriptional regulator
HV340_RS22560	COG0371	Dehydrogenase
HV340_RS22565	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HV340_RS22575	COG0527	aspartate kinase activity
HV340_RS22575	COG0460	homoserine dehydrogenase
HV340_RS22580	COG0626	cystathionine gamma-synthase activity
HV340_RS22590	COG0254	rRNA binding
HV340_RS22595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV340_RS22600	COG1609	Transcriptional regulator
HV340_RS22605	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV340_RS22620	COG1575	Belongs to the MenA family. Type 1 subfamily
HV340_RS22630	COG3074	FtsZ-dependent cytokinesis
HV340_RS22640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV340_RS22645	COG1494	fructose-1,6-bisphosphatase
HV340_RS22655	COG3152	Membrane
HV340_RS22665	COG0149	triose-phosphate isomerase activity
HV340_RS22675	COG2134	cdp-diacylglycerol pyrophosphatase
HV340_RS22685	COG0205	6-phosphofructokinase activity
HV340_RS22695	COG3678	ATP-independent chaperone mediated protein folding
HV340_RS22700	COG0745	RESPONSE REGULATOR receiver
HV340_RS22705	COG2205	protein histidine kinase activity
HV340_RS22710	COG2258	MOSC domain
HV340_RS22725	COG1917	Cupin 2, conserved barrel domain protein
HV340_RS22725	COG4977	sequence-specific DNA binding
HV340_RS22730	COG4977	sequence-specific DNA binding
HV340_RS22735	COG1070	Carbohydrate kinase
HV340_RS22740	COG4806	L-rhamnose isomerase
HV340_RS22750	COG3254	rhamnose metabolic process
HV340_RS22755	COG2211	Major facilitator Superfamily
HV340_RS22775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV340_RS22800	COG0437	4 iron, 4 sulfur cluster binding
HV340_RS22805	COG2864	formate dehydrogenase
HV340_RS22810	COG3058	Necessary for formate dehydrogenase activity
HV340_RS22820	COG0456	acetyltransferase
HV340_RS22835	COG1011	Hydrolase
HV340_RS22840	COG1349	DNA-binding transcription factor activity
HV340_RS22845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV340_RS22855	COG3684	Belongs to the aldolase LacD family
HV340_RS22880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV340_RS22895	COG3852	Histidine kinase
HV340_RS22910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV340_RS22915	COG3078	GTPase activator activity
HV340_RS22930	COG0204	Acyl-transferase
HV340_RS22940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HV340_RS22945	COG3084	Protein conserved in bacteria
HV340_RS22950	COG0746	molybdenum cofactor guanylyltransferase activity
HV340_RS22955	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV340_RS22980	COG2186	Transcriptional regulator
HV340_RS22985	COG0477	Major facilitator Superfamily
HV340_RS22990	COG1609	Transcriptional regulator
HV340_RS22995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV340_RS23005	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV340_RS23010	COG1129	ABC transporter
HV340_RS23015	COG1869	D-ribose catabolic process
HV340_RS23020	COG3158	transport of potassium into the cell
HV340_RS23030	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HV340_RS23035	COG2502	aspartate--ammonia ligase
HV340_RS23040	COG1522	sequence-specific DNA binding
HV340_RS23045	COG0716	FMN binding
HV340_RS23050	COG0445	tRNA wobble uridine modification
HV340_RS23055	COG0357	Ribosomal RNA small subunit methyltransferase G
HV340_RS23060	COG3312	ion transport
HV340_RS23065	COG0356	it plays a direct role in the translocation of protons across the membrane
HV340_RS23075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HV340_RS23080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HV340_RS23085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HV340_RS23095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HV340_RS23100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HV340_RS23105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV340_RS23115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV340_RS23120	COG0573	inorganic phosphate transmembrane transporter activity
HV340_RS23125	COG0581	inorganic phosphate transmembrane transporter activity
HV340_RS23135	COG0704	Plays a role in the regulation of phosphate uptake
HV340_RS23140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV340_RS23145	COG2252	PERMEase
HV340_RS23150	COG0431	NADPH-dependent FMN reductase
HV340_RS23155	COG2091	lysine biosynthetic process via aminoadipic acid
HV340_RS23170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HV340_RS23175	COG0706	membrane insertase activity
HV340_RS23215	COG3706	GGDEF domain
HV340_RS23260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV340_RS23265	COG0501	Belongs to the peptidase M48B family
HV340_RS23325	COG0542	response to heat
HV340_RS23330	COG0071	Belongs to the small heat shock protein (HSP20) family
HV340_RS23355	COG3039	Transposase
HV340_RS23365	COG2205	protein histidine kinase activity
HV340_RS23370	COG0745	RESPONSE REGULATOR receiver
HV340_RS23375	COG1276	copper resistance
HV340_RS23380	COG2372	response to copper ion
HV340_RS23385	COG3667	copper resistance
HV340_RS23390	COG2132	Multicopper oxidase
HV340_RS23400	COG0739	heme binding
HV340_RS23430	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV340_RS23480	COG3706	GGDEF domain
HV340_RS23515	COG1192	Involved in chromosome partitioning
HV340_RS23615	COG1475	DNA binding
HV340_RS23645	COG2801	Transposase and inactivated derivatives
HV340_RS23660	COG3077	Addiction module antitoxin, RelB DinJ family
HV340_RS23665	COG2026	Addiction module toxin, RelE StbE family
HV340_RS23770	COG2223	nitrite transmembrane transporter activity
HV340_RS23780	COG1609	Transcriptional regulator
HV340_RS23795	COG3436	PFAM IS66 Orf2 family protein
HV340_RS23800	COG1120	ATPase activity
HV340_RS23805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS23810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV340_RS23815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HV340_RS23820	COG4772	TonB-dependent receptor
HV340_RS23825	COG3712	iron ion homeostasis
HV340_RS23830	COG1595	DNA-templated transcription, initiation
HV340_RS23840	COG0154	amidase activity
HV340_RS23855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV340_RS23875	COG2985	domain, Protein
HV340_RS23885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV340_RS23925	COG3039	Transposase
HV340_RS23935	COG4974	Belongs to the 'phage' integrase family
HV340_RS23975	COG3077	Addiction module antitoxin, RelB DinJ family
HV340_RS23980	COG3041	Addiction module toxin RelE StbE family
HV340_RS24100	COG1192	Involved in chromosome partitioning