locus-tag	class	description
GKQ55_RS00015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKQ55_RS00020	COG0346	lactoylglutathione lyase activity
GKQ55_RS00025	COG2076	Multidrug Resistance protein
GKQ55_RS00030	COG2076	Multidrug Resistance protein
GKQ55_RS00035	COG3469	chitinase activity
GKQ55_RS00040	COG3397	chitin binding
GKQ55_RS00050	COG1801	Protein of unknown function DUF72
GKQ55_RS00060	COG0527	aspartate kinase activity
GKQ55_RS00065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKQ55_RS00070	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKQ55_RS00075	COG1104	cysteine desulfurase activity
GKQ55_RS00080	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS00085	COG5002	protein histidine kinase activity
GKQ55_RS00130	COG3835	regulator
GKQ55_RS00135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GKQ55_RS00150	COG0549	Belongs to the carbamate kinase family
GKQ55_RS00160	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GKQ55_RS00185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GKQ55_RS00190	COG0628	permease
GKQ55_RS00210	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKQ55_RS00220	COG1846	Transcriptional regulator
GKQ55_RS00225	COG0778	Nitroreductase
GKQ55_RS00230	COG0561	phosphatase activity
GKQ55_RS00240	COG3711	transcriptional antiterminator
GKQ55_RS00245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS00255	COG2213	PTS system mannitol-specific
GKQ55_RS00260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS00265	COG0246	Mannitol dehydrogenase
GKQ55_RS00275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKQ55_RS00290	COG0577	efflux transmembrane transporter activity
GKQ55_RS00290	COG1136	(ABC) transporter
GKQ55_RS00295	COG0577	efflux transmembrane transporter activity
GKQ55_RS00310	COG2814	Major facilitator Superfamily
GKQ55_RS00320	COG1414	Transcriptional regulator
GKQ55_RS00325	COG0800	Aldolase
GKQ55_RS00335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GKQ55_RS00340	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ55_RS00345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKQ55_RS00370	COG1070	Carbohydrate kinase
GKQ55_RS00375	COG4806	L-rhamnose isomerase
GKQ55_RS00380	COG0235	Class ii aldolase
GKQ55_RS00385	COG3254	rhamnose metabolic process
GKQ55_RS00405	COG3104	oligopeptide transport
GKQ55_RS00410	COG1388	LysM domain
GKQ55_RS00410	COG3942	CHAP domain
GKQ55_RS00420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKQ55_RS00425	COG0318	PFAM AMP-dependent synthetase and ligase
GKQ55_RS00430	COG1169	isochorismate synthase
GKQ55_RS00435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKQ55_RS00440	COG2267	carboxylic ester hydrolase activity
GKQ55_RS00445	COG4948	Mandelate Racemase Muconate Lactonizing
GKQ55_RS00450	COG0363	glucosamine-6-phosphate deaminase activity
GKQ55_RS00455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKQ55_RS00460	COG1764	response to oxidative stress
GKQ55_RS00475	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS00480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS00490	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKQ55_RS00495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKQ55_RS00510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GKQ55_RS00515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKQ55_RS00520	COG1316	TRANSCRIPTIONal
GKQ55_RS00525	COG0363	glucosamine-6-phosphate deaminase activity
GKQ55_RS00530	COG1285	pathogenesis
GKQ55_RS00550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKQ55_RS00555	COG1780	Probably involved in ribonucleotide reductase function
GKQ55_RS00560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GKQ55_RS00580	COG0582	viral genome integration into host DNA
GKQ55_RS00615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKQ55_RS00680	COG1917	Cupin 2, conserved barrel domain protein
GKQ55_RS00680	COG2207	Transcriptional regulator
GKQ55_RS00720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GKQ55_RS00725	COG1263	PTS System
GKQ55_RS00725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS00725	COG2190	(PTS) system
GKQ55_RS00730	COG2190	(PTS) system
GKQ55_RS00730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS00730	COG1263	PTS System
GKQ55_RS00745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GKQ55_RS00770	COG2801	Transposase and inactivated derivatives
GKQ55_RS00795	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS00800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS00800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS00810	COG2115	Belongs to the xylose isomerase family
GKQ55_RS00815	COG1070	Carbohydrate kinase
GKQ55_RS00835	COG3328	transposase activity
GKQ55_RS00850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS00855	COG3414	Phosphotransferase system galactitol-specific IIB component
GKQ55_RS00860	COG3775	system Galactitol-specific IIC component
GKQ55_RS00890	COG2188	Transcriptional regulator
GKQ55_RS00915	COG0534	Mate efflux family protein
GKQ55_RS00920	COG0588	phosphoglycerate mutase activity
GKQ55_RS00980	COG1309	transcriptional regulator
GKQ55_RS00990	COG1129	ABC transporter
GKQ55_RS01000	COG1132	(ABC) transporter
GKQ55_RS01005	COG1132	(ABC) transporter
GKQ55_RS01010	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKQ55_RS01015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GKQ55_RS01025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKQ55_RS01070	COG1378	Sugar-specific transcriptional regulator TrmB
GKQ55_RS01100	COG0656	L-ascorbic acid biosynthetic process
GKQ55_RS01110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKQ55_RS01125	COG1113	amino acid transport
GKQ55_RS01145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GKQ55_RS01150	COG0039	L-malate dehydrogenase activity
GKQ55_RS01165	COG0583	DNA-binding transcription factor activity
GKQ55_RS01180	COG1733	regulation of RNA biosynthetic process
GKQ55_RS01185	COG0778	Nitroreductase
GKQ55_RS01190	COG0095	Lipoate-protein ligase
GKQ55_RS01210	COG1609	Transcriptional regulator
GKQ55_RS01220	COG2514	catechol 2,3-dioxygenase activity
GKQ55_RS01225	COG1349	DNA-binding transcription factor activity
GKQ55_RS01255	COG0217	transcriptional regulatory protein
GKQ55_RS01270	COG0346	lactoylglutathione lyase activity
GKQ55_RS01285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKQ55_RS01290	COG2244	polysaccharide biosynthetic process
GKQ55_RS01295	COG1187	pseudouridine synthase activity
GKQ55_RS01310	COG3594	Acyltransferase
GKQ55_RS01315	COG1125	glycine betaine transport
GKQ55_RS01315	COG0517	IMP dehydrogenase activity
GKQ55_RS01320	COG1732	Glycine betaine
GKQ55_RS01325	COG1438	arginine binding
GKQ55_RS01330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKQ55_RS01335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKQ55_RS01340	COG0564	pseudouridine synthase activity
GKQ55_RS01345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKQ55_RS01350	COG3679	Belongs to the UPF0342 family
GKQ55_RS01365	COG3481	metal-dependent phosphohydrolase, HD sub domain
GKQ55_RS01370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GKQ55_RS01385	COG0537	adenosine 5'-monophosphoramidase activity
GKQ55_RS01390	COG1131	(ABC) transporter
GKQ55_RS01395	COG4473	ABC transporter
GKQ55_RS01400	COG0510	thiamine kinase activity
GKQ55_RS01405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GKQ55_RS01420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS01420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS01420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS01430	COG3684	Belongs to the aldolase LacD family
GKQ55_RS01435	COG3557	Belongs to the UPF0374 family
GKQ55_RS01445	COG0628	permease
GKQ55_RS01450	COG1253	flavin adenine dinucleotide binding
GKQ55_RS01455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKQ55_RS01460	COG4974	Belongs to the 'phage' integrase family
GKQ55_RS01520	COG0542	response to heat
GKQ55_RS01530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS01535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKQ55_RS01555	COG0544	peptidyl-prolyl cis-trans isomerase activity
GKQ55_RS01565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS01565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS01565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS01570	COG1105	Belongs to the carbohydrate kinase PfkB family
GKQ55_RS01575	COG1349	DNA-binding transcription factor activity
GKQ55_RS01585	COG0210	DNA helicase
GKQ55_RS01590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKQ55_RS01595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKQ55_RS01600	COG0154	amidase activity
GKQ55_RS01605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKQ55_RS01610	COG1597	lipid kinase activity
GKQ55_RS01615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKQ55_RS01625	COG2197	response regulator
GKQ55_RS01630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKQ55_RS01635	COG0531	amino acid
GKQ55_RS01640	COG2957	Belongs to the agmatine deiminase family
GKQ55_RS01645	COG0549	Belongs to the carbamate kinase family
GKQ55_RS01650	COG0154	amidase activity
GKQ55_RS01660	COG1428	Deoxynucleoside kinase
GKQ55_RS01690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GKQ55_RS01745	COG2217	Heavy metal translocating P-type atpase
GKQ55_RS01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKQ55_RS01765	COG0556	nucleotide-excision repair
GKQ55_RS01770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GKQ55_RS01780	COG1660	Displays ATPase and GTPase activities
GKQ55_RS01790	COG1481	regulation of sporulation
GKQ55_RS01805	COG0740	serine-type endopeptidase activity
GKQ55_RS01835	COG0584	glycerophosphoryl diester phosphodiesterase
GKQ55_RS01845	COG1278	Cold shock
GKQ55_RS01855	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GKQ55_RS01860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKQ55_RS01860	COG2755	lipolytic protein G-D-S-L family
GKQ55_RS01865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKQ55_RS01890	COG1132	(ABC) transporter
GKQ55_RS01895	COG1309	transcriptional regulator
GKQ55_RS01900	COG0577	efflux transmembrane transporter activity
GKQ55_RS01905	COG1136	(ABC) transporter
GKQ55_RS01910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GKQ55_RS01920	COG0671	phosphoesterase, PA-phosphatase related
GKQ55_RS01935	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKQ55_RS01935	COG1388	LysM domain
GKQ55_RS01940	COG0495	leucyl-tRNA aminoacylation
GKQ55_RS01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKQ55_RS01960	COG1126	abc transporter atp-binding protein
GKQ55_RS01965	COG0765	amino acid transport
GKQ55_RS01970	COG4166	transmembrane transport
GKQ55_RS01985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GKQ55_RS01990	COG1187	pseudouridine synthase activity
GKQ55_RS01995	COG1011	Hydrolase
GKQ55_RS02010	COG2337	Toxic component of a toxin-antitoxin (TA) module
GKQ55_RS02015	COG0673	inositol 2-dehydrogenase activity
GKQ55_RS02020	COG3711	transcriptional antiterminator
GKQ55_RS02050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS02065	COG3964	amidohydrolase
GKQ55_RS02085	COG0187	DNA topoisomerase II activity
GKQ55_RS02090	COG1671	Belongs to the UPF0178 family
GKQ55_RS02095	COG1181	Belongs to the D-alanine--D-alanine ligase family
GKQ55_RS02100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GKQ55_RS02115	COG0736	holo-[acyl-carrier-protein] synthase activity
GKQ55_RS02120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKQ55_RS02125	COG2337	Toxic component of a toxin-antitoxin (TA) module
GKQ55_RS02155	COG2365	Tyrosine phosphatase family
GKQ55_RS02175	COG0531	amino acid
GKQ55_RS02185	COG1174	glycine betaine transport
GKQ55_RS02205	COG0346	lactoylglutathione lyase activity
GKQ55_RS02210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKQ55_RS02230	COG3158	transport of potassium into the cell
GKQ55_RS02240	COG2217	Heavy metal translocating P-type atpase
GKQ55_RS02250	COG4989	oxidoreductase activity
GKQ55_RS02255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKQ55_RS02255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKQ55_RS02260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GKQ55_RS02265	COG0237	dephospho-CoA kinase activity
GKQ55_RS02270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKQ55_RS02275	COG3611	Membrane attachment protein
GKQ55_RS02280	COG1484	DNA-dependent DNA replication
GKQ55_RS02300	COG1215	transferase activity, transferring glycosyl groups
GKQ55_RS02325	COG1126	abc transporter atp-binding protein
GKQ55_RS02335	COG0371	Dehydrogenase
GKQ55_RS02340	COG0343	queuine tRNA-ribosyltransferase activity
GKQ55_RS02345	COG1862	Preprotein translocase
GKQ55_RS02355	COG1012	belongs to the aldehyde dehydrogenase family
GKQ55_RS02355	COG1454	alcohol dehydrogenase
GKQ55_RS02360	COG1304	FMN binding
GKQ55_RS02390	COG4166	transmembrane transport
GKQ55_RS02400	COG0601	transmembrane transport
GKQ55_RS02405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKQ55_RS02410	COG0444	Belongs to the ABC transporter superfamily
GKQ55_RS02415	COG4608	Belongs to the ABC transporter superfamily
GKQ55_RS02425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKQ55_RS02430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GKQ55_RS02435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKQ55_RS02440	COG2315	Protein conserved in bacteria
GKQ55_RS02445	COG3759	membrane
GKQ55_RS02455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKQ55_RS02455	COG0456	acetyltransferase
GKQ55_RS02460	COG0659	secondary active sulfate transmembrane transporter activity
GKQ55_RS02465	COG2855	membrane
GKQ55_RS02485	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS02490	COG2205	protein histidine kinase activity
GKQ55_RS02495	COG4975	Glucose uptake
GKQ55_RS02500	COG0531	amino acid
GKQ55_RS02505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ55_RS02505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ55_RS02515	COG3973	AAA domain
GKQ55_RS02520	COG0084	hydrolase, TatD family'
GKQ55_RS02525	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKQ55_RS02530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GKQ55_RS02540	COG3842	ATPase activity
GKQ55_RS02545	COG1803	Methylglyoxal synthase
GKQ55_RS02550	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKQ55_RS02555	COG1132	(ABC) transporter
GKQ55_RS02570	COG3584	3D domain protein
GKQ55_RS02585	COG0561	phosphatase activity
GKQ55_RS02590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKQ55_RS02595	COG0280	phosphate acetyltransferase
GKQ55_RS02600	COG0802	atpase or kinase
GKQ55_RS02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKQ55_RS02615	COG1609	Transcriptional regulator
GKQ55_RS02620	COG2017	converts alpha-aldose to the beta-anomer
GKQ55_RS02625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKQ55_RS02635	COG2190	(PTS) system
GKQ55_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS02635	COG1263	PTS System
GKQ55_RS02645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKQ55_RS02710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GKQ55_RS02720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GKQ55_RS02745	COG1396	sequence-specific DNA binding
GKQ55_RS02760	COG3646	Phage regulatory protein
GKQ55_RS02900	COG1783	phage Terminase large subunit
GKQ55_RS02910	COG2868	ribosomal protein
GKQ55_RS03000	COG3942	CHAP domain
GKQ55_RS03000	COG1388	LysM domain
GKQ55_RS03035	COG3223	Belongs to the PsiE family
GKQ55_RS03040	COG1408	metallophosphoesterase
GKQ55_RS03045	COG0006	proline dipeptidase activity
GKQ55_RS03050	COG1694	Mazg nucleotide pyrophosphohydrolase
GKQ55_RS03055	COG1302	Protein conserved in bacteria
GKQ55_RS03060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKQ55_RS03065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKQ55_RS03070	COG1570	exodeoxyribonuclease VII activity
GKQ55_RS03075	COG1722	exodeoxyribonuclease VII activity
GKQ55_RS03080	COG0142	geranyltranstransferase activity
GKQ55_RS03085	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GKQ55_RS03100	COG1438	arginine binding
GKQ55_RS03105	COG0497	DNA recombination
GKQ55_RS03125	COG2001	Belongs to the MraZ family
GKQ55_RS03130	COG0275	rRNA processing
GKQ55_RS03140	COG0768	penicillin binding
GKQ55_RS03145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKQ55_RS03150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKQ55_RS03155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKQ55_RS03160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GKQ55_RS03165	COG0849	cell division
GKQ55_RS03170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKQ55_RS03175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKQ55_RS03180	COG1799	cell septum assembly
GKQ55_RS03185	COG0762	integral membrane protein
GKQ55_RS03190	COG2302	S4 RNA-binding domain
GKQ55_RS03195	COG3599	regulation of cell shape
GKQ55_RS03200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKQ55_RS03205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKQ55_RS03225	COG0673	inositol 2-dehydrogenase activity
GKQ55_RS03235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GKQ55_RS03235	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GKQ55_RS03240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS03245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS03265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS03270	COG1447	Phosphotransferase system cellobiose-specific component IIA
GKQ55_RS03275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS03280	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS03300	COG0574	Belongs to the PEP-utilizing enzyme family
GKQ55_RS03300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKQ55_RS03305	COG0517	IMP dehydrogenase activity
GKQ55_RS03310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GKQ55_RS03315	COG0392	lysyltransferase activity
GKQ55_RS03315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKQ55_RS03355	COG0105	UTP biosynthetic process
GKQ55_RS03370	COG0561	phosphatase activity
GKQ55_RS03380	COG2252	PERMEase
GKQ55_RS03385	COG2814	Major facilitator Superfamily
GKQ55_RS03395	COG0587	DNA-directed DNA polymerase activity
GKQ55_RS03400	COG0205	6-phosphofructokinase activity
GKQ55_RS03415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GKQ55_RS03420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKQ55_RS03425	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS03430	COG5002	protein histidine kinase activity
GKQ55_RS03520	COG1116	anion transmembrane transporter activity
GKQ55_RS03525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GKQ55_RS03535	COG1660	Displays ATPase and GTPase activities
GKQ55_RS03540	COG1914	H( )-stimulated, divalent metal cation uptake system
GKQ55_RS03550	COG2508	Transcriptional regulator
GKQ55_RS03555	COG4166	transmembrane transport
GKQ55_RS03560	COG0402	S-adenosylhomocysteine deaminase activity
GKQ55_RS03565	COG0402	S-adenosylhomocysteine deaminase activity
GKQ55_RS03570	COG1956	GAF domain-containing protein
GKQ55_RS03580	COG0110	maltose O-acetyltransferase activity
GKQ55_RS03595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKQ55_RS03600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKQ55_RS03605	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GKQ55_RS03610	COG1609	Transcriptional regulator
GKQ55_RS03615	COG0572	uridine kinase
GKQ55_RS03640	COG2814	Major facilitator Superfamily
GKQ55_RS03645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKQ55_RS03675	COG0456	acetyltransferase
GKQ55_RS03745	COG1132	(ABC) transporter
GKQ55_RS03760	COG1113	amino acid transport
GKQ55_RS03775	COG0247	lactate metabolic process
GKQ55_RS03780	COG1139	Iron-sulfur cluster binding protein
GKQ55_RS03795	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GKQ55_RS03800	COG1074	ATP-dependent DNA helicase activity
GKQ55_RS03805	COG1733	regulation of RNA biosynthetic process
GKQ55_RS03810	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKQ55_RS03815	COG0072	phenylalanine-tRNA ligase activity
GKQ55_RS03815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ55_RS03820	COG0765	amino acid transport
GKQ55_RS03825	COG0765	amino acid transport
GKQ55_RS03830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKQ55_RS03840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GKQ55_RS03845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GKQ55_RS03850	COG0622	Phosphoesterase
GKQ55_RS03855	COG1349	DNA-binding transcription factor activity
GKQ55_RS03865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS03870	COG3037	sugar-specific permease SgaT UlaA
GKQ55_RS03880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GKQ55_RS03885	COG3623	hexulose-6-phosphate isomerase
GKQ55_RS03895	COG0517	IMP dehydrogenase activity
GKQ55_RS03900	COG2171	N-acyltransferase activity
GKQ55_RS03905	COG1473	amidohydrolase
GKQ55_RS03910	COG0668	transmembrane transport
GKQ55_RS03920	COG0656	L-ascorbic acid biosynthetic process
GKQ55_RS03925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GKQ55_RS03945	COG1078	dGTPase activity
GKQ55_RS03950	COG0095	Lipoate-protein ligase
GKQ55_RS03965	COG0504	CTP synthase activity
GKQ55_RS03970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKQ55_RS03975	COG3331	DNA recombination
GKQ55_RS03980	COG4474	Belongs to the UPF0398 family
GKQ55_RS03985	COG3599	regulation of cell shape
GKQ55_RS03995	COG0116	Belongs to the methyltransferase superfamily
GKQ55_RS04000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GKQ55_RS04005	COG3935	DnaD domain protein
GKQ55_RS04010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKQ55_RS04015	COG2188	Transcriptional regulator
GKQ55_RS04025	COG1446	asparaginase
GKQ55_RS04030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS04035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS04060	COG1666	GTP binding
GKQ55_RS04065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKQ55_RS04070	COG0191	fructose-bisphosphate aldolase activity
GKQ55_RS04075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKQ55_RS04080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GKQ55_RS04085	COG0254	rRNA binding
GKQ55_RS04100	COG1940	carbohydrate kinase activity
GKQ55_RS04105	COG3237	CsbD-like
GKQ55_RS04110	COG0778	Nitroreductase
GKQ55_RS04115	COG1854	S-ribosylhomocysteine lyase activity
GKQ55_RS04120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKQ55_RS04125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKQ55_RS04135	COG0737	Belongs to the 5'-nucleotidase family
GKQ55_RS04140	COG4470	Protein conserved in bacteria
GKQ55_RS04145	COG0647	UMP catabolic process
GKQ55_RS04160	COG1307	EDD domain protein, DegV family
GKQ55_RS04165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GKQ55_RS04170	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS04175	COG5002	protein histidine kinase activity
GKQ55_RS04190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GKQ55_RS04195	COG0701	Predicted permease
GKQ55_RS04200	COG3689	TIGRFAM TIGR03943 family protein
GKQ55_RS04215	COG4472	Bacterial protein of unknown function (DUF965)
GKQ55_RS04220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKQ55_RS04225	COG3906	Belongs to the UPF0473 family
GKQ55_RS04240	COG3493	citrate carrier protein
GKQ55_RS04245	COG3290	protein histidine kinase activity
GKQ55_RS04250	COG4565	transcriptional regulatory protein
GKQ55_RS04255	COG0446	pyridine nucleotide-disulphide oxidoreductase
GKQ55_RS04260	COG1316	TRANSCRIPTIONal
GKQ55_RS04265	COG0028	Belongs to the TPP enzyme family
GKQ55_RS04270	COG3527	Alpha-acetolactate decarboxylase
GKQ55_RS04290	COG1175	transmembrane transport
GKQ55_RS04300	COG3842	ATPase activity
GKQ55_RS04310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GKQ55_RS04315	COG0402	S-adenosylhomocysteine deaminase activity
GKQ55_RS04335	COG1053	succinate dehydrogenase
GKQ55_RS04335	COG3976	FMN-binding domain protein
GKQ55_RS04335	COG0431	NADPH-dependent FMN reductase
GKQ55_RS04350	COG1408	metallophosphoesterase
GKQ55_RS04355	COG4209	transmembrane transport
GKQ55_RS04360	COG0395	ABC-type sugar transport system, permease component
GKQ55_RS04375	COG3458	cephalosporin-C deacetylase activity
GKQ55_RS04390	COG3459	Glycosyltransferase 36 associated
GKQ55_RS04395	COG1609	Transcriptional regulator
GKQ55_RS04405	COG2188	Transcriptional regulator
GKQ55_RS04410	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS04415	COG0673	inositol 2-dehydrogenase activity
GKQ55_RS04420	COG2707	UPF0756 membrane protein
GKQ55_RS04435	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GKQ55_RS04455	COG1122	ATPase activity
GKQ55_RS04475	COG0561	phosphatase activity
GKQ55_RS04480	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS04485	COG3850	Histidine kinase
GKQ55_RS04485	COG5002	protein histidine kinase activity
GKQ55_RS04500	COG1368	sulfuric ester hydrolase activity
GKQ55_RS04505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKQ55_RS04510	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKQ55_RS04515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKQ55_RS04520	COG1388	LysM domain
GKQ55_RS04520	COG4932	domain protein
GKQ55_RS04525	COG0779	Required for maturation of 30S ribosomal subunits
GKQ55_RS04530	COG0195	Participates in both transcription termination and antitermination
GKQ55_RS04535	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GKQ55_RS04545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKQ55_RS04550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKQ55_RS04630	COG4824	toxin secretion phage lysis holin
GKQ55_RS04640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKQ55_RS04645	COG0196	riboflavin kinase activity
GKQ55_RS04655	COG1695	Transcriptional regulator
GKQ55_RS04675	COG0772	Belongs to the SEDS family
GKQ55_RS04680	COG0583	DNA-binding transcription factor activity
GKQ55_RS04690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKQ55_RS04695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GKQ55_RS04700	COG1420	regulation of RNA biosynthetic process
GKQ55_RS04705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKQ55_RS04710	COG0443	Heat shock 70 kDa protein
GKQ55_RS04715	COG0484	heat shock protein binding
GKQ55_RS04720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GKQ55_RS04725	COG2183	response to ionizing radiation
GKQ55_RS04730	COG3091	SprT-like family
GKQ55_RS04740	COG0436	Aminotransferase
GKQ55_RS04785	COG2268	Band 7 protein
GKQ55_RS04810	COG1309	transcriptional regulator
GKQ55_RS04820	COG2188	Transcriptional regulator
GKQ55_RS04825	COG4842	Belongs to the WXG100 family
GKQ55_RS04845	COG4499	WXG100 protein secretion system (Wss), protein YukC
GKQ55_RS04915	COG0492	ferredoxin-NADP+ reductase activity
GKQ55_RS04930	COG0577	efflux transmembrane transporter activity
GKQ55_RS04930	COG1136	(ABC) transporter
GKQ55_RS04930	COG1136	(ABC) transporter
GKQ55_RS04930	COG0577	efflux transmembrane transporter activity
GKQ55_RS04940	COG3833	ABC-type maltose transport systems, permease component
GKQ55_RS04945	COG1175	transmembrane transport
GKQ55_RS04950	COG2182	Extracellular solute-binding protein
GKQ55_RS04955	COG0366	Alpha amylase catalytic
GKQ55_RS04960	COG0366	Alpha amylase catalytic
GKQ55_RS04965	COG0366	Alpha amylase catalytic
GKQ55_RS04975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKQ55_RS05005	COG0371	Dehydrogenase
GKQ55_RS05010	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GKQ55_RS05015	COG2376	Dihydroxyacetone kinase
GKQ55_RS05020	COG1461	Dihydroxyacetone kinase
GKQ55_RS05030	COG3425	synthase
GKQ55_RS05040	COG0628	permease
GKQ55_RS05050	COG1278	Cold shock
GKQ55_RS05065	COG2814	Major facilitator Superfamily
GKQ55_RS05070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GKQ55_RS05075	COG4109	DRTGG domain
GKQ55_RS05080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GKQ55_RS05085	COG2824	Alkylphosphonate utilization operon protein PhnA
GKQ55_RS05100	COG0513	Belongs to the DEAD box helicase family
GKQ55_RS05110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKQ55_RS05115	COG2384	SAM-dependent methyltransferase
GKQ55_RS05120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKQ55_RS05125	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKQ55_RS05140	COG0746	molybdenum cofactor guanylyltransferase activity
GKQ55_RS05160	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GKQ55_RS05165	COG3383	formate dehydrogenase (NAD+) activity
GKQ55_RS05170	COG0303	'Molybdopterin
GKQ55_RS05175	COG0315	cyclic pyranopterin monophosphate synthase activity
GKQ55_RS05190	COG0521	Mo-molybdopterin cofactor biosynthetic process
GKQ55_RS05200	COG0725	ABC transporter, periplasmic molybdate-binding protein
GKQ55_RS05205	COG4149	molybdate abc transporter
GKQ55_RS05210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GKQ55_RS05215	COG2217	Heavy metal translocating P-type atpase
GKQ55_RS05225	COG1286	toxin biosynthetic process
GKQ55_RS05230	COG1193	negative regulation of DNA recombination
GKQ55_RS05235	COG3118	belongs to the thioredoxin family
GKQ55_RS05240	COG0322	excinuclease ABC activity
GKQ55_RS05250	COG4152	abc transporter atp-binding protein
GKQ55_RS05255	COG1668	transmembrane transport
GKQ55_RS05265	COG1486	melibiose metabolic process
GKQ55_RS05280	COG2081	HI0933 family
GKQ55_RS05290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKQ55_RS05295	COG0166	Belongs to the GPI family
GKQ55_RS05315	COG1269	ATP hydrolysis coupled proton transport
GKQ55_RS05320	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKQ55_RS05325	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
GKQ55_RS05330	COG1527	subunit (C
GKQ55_RS05335	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
GKQ55_RS05340	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GKQ55_RS05345	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
GKQ55_RS05350	COG1394	ATPase activity, coupled to movement of substances
GKQ55_RS05360	COG1595	DNA-templated transcription, initiation
GKQ55_RS05380	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GKQ55_RS05385	COG0019	diaminopimelate decarboxylase activity
GKQ55_RS05410	COG2151	metal-sulfur cluster biosynthetic enzyme
GKQ55_RS05415	COG4948	Mandelate Racemase Muconate Lactonizing
GKQ55_RS05425	COG4166	transmembrane transport
GKQ55_RS05430	COG3711	transcriptional antiterminator
GKQ55_RS05440	COG3711	transcriptional antiterminator
GKQ55_RS05440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS05450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS05450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS05450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GKQ55_RS05455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS05465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GKQ55_RS05470	COG0741	lytic transglycosylase activity
GKQ55_RS05475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKQ55_RS05480	COG0358	DNA primase activity
GKQ55_RS05485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKQ55_RS05495	COG2996	Protein conserved in bacteria
GKQ55_RS05500	COG0735	belongs to the Fur family
GKQ55_RS05510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKQ55_RS05520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS05535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKQ55_RS05550	COG4974	Belongs to the 'phage' integrase family
GKQ55_RS05555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKQ55_RS05560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKQ55_RS05565	COG1187	pseudouridine synthase activity
GKQ55_RS05570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKQ55_RS05590	COG0514	ATP-dependent DNA helicase (RecQ)
GKQ55_RS05600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GKQ55_RS05605	COG0539	negative regulation of cytoplasmic translation
GKQ55_RS05610	COG1160	GTP binding
GKQ55_RS05625	COG0457	Tetratricopeptide repeat
GKQ55_RS05630	COG5582	Belongs to the UPF0302 family
GKQ55_RS05635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKQ55_RS05640	COG1694	Mazg nucleotide pyrophosphohydrolase
GKQ55_RS05645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GKQ55_RS05650	COG0617	tRNA 3'-terminal CCA addition
GKQ55_RS05665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKQ55_RS05670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GKQ55_RS05680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKQ55_RS05685	COG0287	Prephenate dehydrogenase
GKQ55_RS05695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKQ55_RS05700	COG0077	Prephenate dehydratase
GKQ55_RS05710	COG1307	EDD domain protein, DegV family
GKQ55_RS05735	COG0488	(ABC) transporter
GKQ55_RS05740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKQ55_RS05750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKQ55_RS05755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKQ55_RS05760	COG4224	UPF0291 protein
GKQ55_RS05770	COG2814	Major facilitator Superfamily
GKQ55_RS05775	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKQ55_RS05775	COG1388	LysM domain
GKQ55_RS05785	COG0735	belongs to the Fur family
GKQ55_RS05790	COG0446	pyridine nucleotide-disulphide oxidoreductase
GKQ55_RS05795	COG2816	NAD+ diphosphatase activity
GKQ55_RS05810	COG2207	Transcriptional regulator
GKQ55_RS05815	COG1132	(ABC) transporter
GKQ55_RS05835	COG0753	catalase activity
GKQ55_RS05840	COG1349	DNA-binding transcription factor activity
GKQ55_RS05845	COG0546	phosphoglycolate phosphatase activity
GKQ55_RS05870	COG2190	(PTS) system
GKQ55_RS05870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS05870	COG1263	PTS System
GKQ55_RS05875	COG0366	Alpha amylase catalytic
GKQ55_RS05885	COG1609	Transcriptional regulator
GKQ55_RS05895	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS05900	COG1263	PTS System
GKQ55_RS05900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS05900	COG2190	(PTS) system
GKQ55_RS05910	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GKQ55_RS05920	COG1227	inorganic diphosphatase activity
GKQ55_RS05925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKQ55_RS05930	COG1882	Formate acetyltransferase
GKQ55_RS05935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKQ55_RS05940	COG0187	DNA topoisomerase II activity
GKQ55_RS05945	COG1832	CoA-binding protein
GKQ55_RS05950	COG4766	ethanolamine catabolic process
GKQ55_RS05955	COG3192	ethanolamine utilization protein
GKQ55_RS05960	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GKQ55_RS05970	COG4869	propanediol catabolic process
GKQ55_RS05985	COG1454	alcohol dehydrogenase
GKQ55_RS05985	COG1012	belongs to the aldehyde dehydrogenase family
GKQ55_RS06000	COG4302	ethanolamine ammonia-lyase activity
GKQ55_RS06005	COG4303	Ethanolamine ammonia lyase large subunit
GKQ55_RS06010	COG4819	ethanolamine utilization protein
GKQ55_RS06035	COG2096	Adenosyltransferase
GKQ55_RS06045	COG1120	ATPase activity
GKQ55_RS06050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKQ55_RS06055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKQ55_RS06060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GKQ55_RS06070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GKQ55_RS06075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKQ55_RS06080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKQ55_RS06090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKQ55_RS06095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKQ55_RS06100	COG1266	CAAX protease self-immunity
GKQ55_RS06105	COG0758	DNA mediated transformation
GKQ55_RS06110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKQ55_RS06120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKQ55_RS06125	COG0583	DNA-binding transcription factor activity
GKQ55_RS06135	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKQ55_RS06140	COG0022	dehydrogenase e1 component
GKQ55_RS06145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GKQ55_RS06150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKQ55_RS06155	COG3426	butyrate kinase activity
GKQ55_RS06160	COG0280	phosphate acetyltransferase
GKQ55_RS06180	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ55_RS06190	COG0346	lactoylglutathione lyase activity
GKQ55_RS06200	COG0604	alcohol dehydrogenase
GKQ55_RS06205	COG0577	efflux transmembrane transporter activity
GKQ55_RS06210	COG1136	(ABC) transporter
GKQ55_RS06225	COG1131	(ABC) transporter
GKQ55_RS06240	COG0681	Belongs to the peptidase S26 family
GKQ55_RS06245	COG3409	Peptidoglycan-binding domain 1 protein
GKQ55_RS06245	COG0793	Belongs to the peptidase S41A family
GKQ55_RS06250	COG4479	Belongs to the UPF0346 family
GKQ55_RS06255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKQ55_RS06260	COG4698	Protein conserved in bacteria
GKQ55_RS06265	COG2755	lipolytic protein G-D-S-L family
GKQ55_RS06270	COG1307	EDD domain protein, DegV family
GKQ55_RS06275	COG1272	protein, Hemolysin III
GKQ55_RS06285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKQ55_RS06290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GKQ55_RS06290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GKQ55_RS06295	COG5416	Lipopolysaccharide assembly protein A domain
GKQ55_RS06300	COG0300	oxidoreductase activity
GKQ55_RS06305	COG1234	tRNA 3'-trailer cleavage
GKQ55_RS06315	COG1837	Belongs to the UPF0109 family
GKQ55_RS06320	COG0228	four-way junction DNA binding
GKQ55_RS06325	COG1214	PFAM Peptidase M22, glycoprotease
GKQ55_RS06325	COG0456	acetyltransferase
GKQ55_RS06330	COG0431	NADPH-dependent FMN reductase
GKQ55_RS06335	COG0789	Transcriptional regulator
GKQ55_RS06340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKQ55_RS06345	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKQ55_RS06350	COG1683	Conserved Protein
GKQ55_RS06355	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS06360	COG5002	protein histidine kinase activity
GKQ55_RS06370	COG0436	Aminotransferase
GKQ55_RS06375	COG0383	alpha-mannosidase activity
GKQ55_RS06390	COG0583	DNA-binding transcription factor activity
GKQ55_RS06405	COG0284	orotidine-5'-phosphate decarboxylase activity
GKQ55_RS06415	COG0543	2 iron, 2 sulfur cluster binding
GKQ55_RS06420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GKQ55_RS06425	COG0505	Belongs to the CarA family
GKQ55_RS06430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GKQ55_RS06435	COG0540	Belongs to the ATCase OTCase family
GKQ55_RS06440	COG2233	PERMEase
GKQ55_RS06450	COG0564	pseudouridine synthase activity
GKQ55_RS06455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKQ55_RS06465	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GKQ55_RS06470	COG1278	Cold shock
GKQ55_RS06480	COG0328	RNA-DNA hybrid ribonuclease activity
GKQ55_RS06485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKQ55_RS06490	COG0710	3-dehydroquinate dehydratase activity
GKQ55_RS06495	COG1132	(ABC) transporter
GKQ55_RS06500	COG1132	(ABC) transporter
GKQ55_RS06505	COG3763	UPF0154 protein
GKQ55_RS06510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GKQ55_RS06525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKQ55_RS06540	COG1131	(ABC) transporter
GKQ55_RS06545	COG1609	Transcriptional regulator
GKQ55_RS06550	COG0006	proline dipeptidase activity
GKQ55_RS06555	COG4980	gas vesicle protein
GKQ55_RS06565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GKQ55_RS06570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GKQ55_RS06575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKQ55_RS06580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKQ55_RS06585	COG0322	excinuclease ABC activity
GKQ55_RS06590	COG1950	PFAM Membrane protein of
GKQ55_RS06600	COG3595	metallopeptidase activity
GKQ55_RS06605	COG0704	Plays a role in the regulation of phosphate uptake
GKQ55_RS06610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKQ55_RS06615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKQ55_RS06620	COG0581	inorganic phosphate transmembrane transporter activity
GKQ55_RS06625	COG0573	inorganic phosphate transmembrane transporter activity
GKQ55_RS06635	COG2177	Part of the ABC transporter FtsEX involved in
GKQ55_RS06640	COG2884	Cell division ATP-binding protein ftsE
GKQ55_RS06650	COG0653	protein targeting
GKQ55_RS06665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GKQ55_RS06670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS06680	COG1739	Uncharacterized protein family UPF0029
GKQ55_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ55_RS06710	COG0151	Belongs to the GarS family
GKQ55_RS06715	COG0138	bifunctional purine biosynthesis protein purh
GKQ55_RS06720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKQ55_RS06725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GKQ55_RS06735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKQ55_RS06740	COG0047	phosphoribosylformylglycinamidine synthase activity
GKQ55_RS06745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKQ55_RS06750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GKQ55_RS06755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKQ55_RS06760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKQ55_RS06770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GKQ55_RS06775	COG4166	transmembrane transport
GKQ55_RS06785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKQ55_RS06790	COG4876	unkown
GKQ55_RS06805	COG0628	permease
GKQ55_RS06820	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS06825	COG3715	PTS system
GKQ55_RS06830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS06830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS06840	COG1105	Belongs to the carbohydrate kinase PfkB family
GKQ55_RS06845	COG3684	Belongs to the aldolase LacD family
GKQ55_RS06850	COG2222	sugar isomerase
GKQ55_RS06855	COG2188	Transcriptional regulator
GKQ55_RS06860	COG1442	glycosyl transferase family 8
GKQ55_RS06865	COG1442	glycosyl transferase family 8
GKQ55_RS06870	COG1368	sulfuric ester hydrolase activity
GKQ55_RS06880	COG0583	DNA-binding transcription factor activity
GKQ55_RS06895	COG3227	Zinc metalloprotease (Elastase)
GKQ55_RS06910	COG0726	polysaccharide deacetylase
GKQ55_RS06920	COG4974	Belongs to the 'phage' integrase family
GKQ55_RS06945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS06960	COG3328	transposase activity
GKQ55_RS06985	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GKQ55_RS06990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GKQ55_RS06995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GKQ55_RS07010	COG5002	protein histidine kinase activity
GKQ55_RS07030	COG1136	(ABC) transporter
GKQ55_RS07045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKQ55_RS07060	COG3328	transposase activity
GKQ55_RS07070	COG0791	NLP P60 protein
GKQ55_RS07070	COG0741	lytic transglycosylase activity
GKQ55_RS07120	COG2946	Replication initiation factor
GKQ55_RS07145	COG1674	ftsk spoiiie
GKQ55_RS07175	COG0335	large ribosomal subunit rRNA binding
GKQ55_RS07180	COG0336	Belongs to the RNA methyltransferase TrmD family
GKQ55_RS07185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKQ55_RS07190	COG1914	H( )-stimulated, divalent metal cation uptake system
GKQ55_RS07200	COG0398	Pfam SNARE associated Golgi protein
GKQ55_RS07205	COG0584	glycerophosphoryl diester phosphodiesterase
GKQ55_RS07225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GKQ55_RS07235	COG4129	membrane
GKQ55_RS07245	COG1940	carbohydrate kinase activity
GKQ55_RS07250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GKQ55_RS07260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GKQ55_RS07265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKQ55_RS07270	COG2706	6-phosphogluconolactonase activity
GKQ55_RS07280	COG3069	C4-dicarboxylate transmembrane transporter activity
GKQ55_RS07310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GKQ55_RS07320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKQ55_RS07360	COG2364	Membrane
GKQ55_RS07365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKQ55_RS07375	COG2814	Major facilitator Superfamily
GKQ55_RS07385	COG1368	sulfuric ester hydrolase activity
GKQ55_RS07410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKQ55_RS07415	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS07420	COG3715	PTS system
GKQ55_RS07435	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GKQ55_RS07435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GKQ55_RS07440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GKQ55_RS07455	COG0149	triose-phosphate isomerase activity
GKQ55_RS07460	COG0126	phosphoglycerate kinase activity
GKQ55_RS07470	COG2390	Transcriptional regulator
GKQ55_RS07475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKQ55_RS07480	COG4475	Protein of unknown function (DUF436)
GKQ55_RS07485	COG4720	Psort location CytoplasmicMembrane, score
GKQ55_RS07490	COG0351	phosphomethylpyrimidine kinase
GKQ55_RS07495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GKQ55_RS07500	COG0124	histidyl-tRNA synthetase
GKQ55_RS07505	COG1490	D-aminoacyl-tRNA deacylase activity
GKQ55_RS07510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKQ55_RS07515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GKQ55_RS07520	COG2264	protein methyltransferase activity
GKQ55_RS07530	COG2094	Belongs to the DNA glycosylase MPG family
GKQ55_RS07535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GKQ55_RS07550	COG0589	response to stress
GKQ55_RS07555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKQ55_RS07560	COG0827	DNA restriction-modification system
GKQ55_RS07595	COG1278	Cold shock
GKQ55_RS07600	COG3942	CHAP domain
GKQ55_RS07600	COG1388	LysM domain
GKQ55_RS07655	COG0228	four-way junction DNA binding
GKQ55_RS07705	COG1783	phage Terminase large subunit
GKQ55_RS07710	COG3728	DNA packaging
GKQ55_RS07810	COG1396	sequence-specific DNA binding
GKQ55_RS07820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKQ55_RS07825	COG0582	viral genome integration into host DNA
GKQ55_RS07835	COG4537	Required for transformation and DNA binding
GKQ55_RS07845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKQ55_RS07850	COG0531	amino acid
GKQ55_RS07855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GKQ55_RS07860	COG0577	efflux transmembrane transporter activity
GKQ55_RS07865	COG1136	(ABC) transporter
GKQ55_RS07875	COG1674	ftsk spoiiie
GKQ55_RS07880	COG1252	NADH dehydrogenase
GKQ55_RS07895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKQ55_RS07900	COG4988	ABC transporter
GKQ55_RS07905	COG1294	oxidase, subunit
GKQ55_RS07910	COG1271	oxidase subunit
GKQ55_RS07915	COG2207	Transcriptional regulator
GKQ55_RS07915	COG3708	Transcriptional regulator
GKQ55_RS07935	COG1881	PFAM PEBP family protein
GKQ55_RS07945	COG0482	sulfurtransferase activity
GKQ55_RS07955	COG1104	cysteine desulfurase activity
GKQ55_RS07960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKQ55_RS07965	COG1121	(ABC) transporter
GKQ55_RS07970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKQ55_RS07980	COG0488	(ABC) transporter
GKQ55_RS07985	COG1473	amidohydrolase
GKQ55_RS07995	COG2011	ABC-type metal ion transport system permease component
GKQ55_RS08000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKQ55_RS08035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKQ55_RS08045	COG1122	ATPase activity
GKQ55_RS08050	COG4720	Psort location CytoplasmicMembrane, score
GKQ55_RS08055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKQ55_RS08065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKQ55_RS08080	COG0789	Transcriptional regulator
GKQ55_RS08085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKQ55_RS08090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKQ55_RS08110	COG4641	Protein conserved in bacteria
GKQ55_RS08110	COG0438	transferase activity, transferring glycosyl groups
GKQ55_RS08115	COG3475	LICD family
GKQ55_RS08125	COG1216	Glycosyl transferase, family 2
GKQ55_RS08125	COG1442	glycosyl transferase family 8
GKQ55_RS08130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKQ55_RS08145	COG3475	LICD family
GKQ55_RS08150	COG1216	Glycosyl transferase, family 2
GKQ55_RS08155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKQ55_RS08170	COG0438	transferase activity, transferring glycosyl groups
GKQ55_RS08170	COG1216	Glycosyl transferase, family 2
GKQ55_RS08175	COG0438	transferase activity, transferring glycosyl groups
GKQ55_RS08175	COG1216	Glycosyl transferase, family 2
GKQ55_RS08180	COG1134	teichoic acid transport
GKQ55_RS08185	COG1682	transport, permease protein
GKQ55_RS08200	COG1215	transferase activity, transferring glycosyl groups
GKQ55_RS08205	COG1091	dTDP-4-dehydrorhamnose reductase activity
GKQ55_RS08210	COG1088	dTDP-glucose 4,6-dehydratase activity
GKQ55_RS08220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKQ55_RS08240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKQ55_RS08245	COG1295	ribonuclease BN
GKQ55_RS08250	COG0024	Methionine aminopeptidase
GKQ55_RS08255	COG0716	FMN binding
GKQ55_RS08260	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GKQ55_RS08265	COG1309	transcriptional regulator
GKQ55_RS08270	COG2309	aminopeptidase activity
GKQ55_RS08280	COG0590	tRNA wobble adenosine to inosine editing
GKQ55_RS08290	COG0384	phenazine biosynthesis protein PhzF
GKQ55_RS08300	COG2738	Putative neutral zinc metallopeptidase
GKQ55_RS08315	COG1263	PTS System
GKQ55_RS08315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS08320	COG0346	lactoylglutathione lyase activity
GKQ55_RS08340	COG2207	Transcriptional regulator
GKQ55_RS08340	COG4753	response regulator
GKQ55_RS08345	COG2972	Histidine kinase
GKQ55_RS08360	COG0395	ABC-type sugar transport system, permease component
GKQ55_RS08365	COG1175	transmembrane transport
GKQ55_RS08370	COG1266	CAAX protease self-immunity
GKQ55_RS08390	COG1132	(ABC) transporter
GKQ55_RS08415	COG0395	ABC-type sugar transport system, permease component
GKQ55_RS08430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKQ55_RS08445	COG1609	Transcriptional regulator
GKQ55_RS08455	COG0481	GTPase activity
GKQ55_RS08470	COG0542	response to heat
GKQ55_RS08480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKQ55_RS08485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKQ55_RS08495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKQ55_RS08505	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKQ55_RS08525	COG0017	Asparaginyl-tRNA synthetase
GKQ55_RS08530	COG0436	Aminotransferase
GKQ55_RS08540	COG1199	ATP-dependent helicase activity
GKQ55_RS08540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKQ55_RS08555	COG0531	amino acid
GKQ55_RS08565	COG0442	prolyl-tRNA aminoacylation
GKQ55_RS08570	COG0750	zinc metalloprotease
GKQ55_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ55_RS08595	COG2197	response regulator
GKQ55_RS08600	COG4585	Histidine kinase
GKQ55_RS08620	COG1132	(ABC) transporter
GKQ55_RS08625	COG1131	(ABC) transporter
GKQ55_RS08705	COG0719	Fe-S assembly protein
GKQ55_RS08715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKQ55_RS08720	COG0719	Fe-S assembly protein
GKQ55_RS08730	COG0233	cytoplasmic translational termination
GKQ55_RS08735	COG0528	UMP kinase activity
GKQ55_RS08740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKQ55_RS08745	COG0052	Belongs to the universal ribosomal protein uS2 family
GKQ55_RS08750	COG0519	Catalyzes the synthesis of GMP from XMP
GKQ55_RS08755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKQ55_RS08760	COG1254	Belongs to the acylphosphatase family
GKQ55_RS08765	COG0706	membrane insertase activity
GKQ55_RS08775	COG0751	glycine-tRNA ligase activity
GKQ55_RS08780	COG0752	glycyl-tRNA synthetase alpha subunit
GKQ55_RS08790	COG1381	Involved in DNA repair and RecF pathway recombination
GKQ55_RS08795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKQ55_RS08800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GKQ55_RS08805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKQ55_RS08815	COG1702	phosphate starvation-inducible protein PhoH
GKQ55_RS08820	COG1610	YqeY-like protein
GKQ55_RS08825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GKQ55_RS08830	COG0735	belongs to the Fur family
GKQ55_RS08835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GKQ55_RS08840	COG0083	homoserine kinase activity
GKQ55_RS08855	COG0640	Transcriptional regulator
GKQ55_RS08860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKQ55_RS08865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKQ55_RS08870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKQ55_RS08885	COG0516	GMP reductase activity
GKQ55_RS08895	COG0402	S-adenosylhomocysteine deaminase activity
GKQ55_RS08910	COG1737	Transcriptional regulator
GKQ55_RS08915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS08915	COG1263	PTS System
GKQ55_RS08920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKQ55_RS08930	COG2190	(PTS) system
GKQ55_RS08930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS08930	COG1263	PTS System
GKQ55_RS08935	COG1968	undecaprenyl-diphosphatase activity
GKQ55_RS08940	COG3394	polysaccharide catabolic process
GKQ55_RS08950	COG0306	phosphate transporter
GKQ55_RS08955	COG0268	Binds directly to 16S ribosomal RNA
GKQ55_RS08960	COG1607	acyl-coa hydrolase
GKQ55_RS08965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKQ55_RS08970	COG1466	dna polymerase III delta subunit
GKQ55_RS08975	COG0658	competence protein
GKQ55_RS08975	COG2333	competence protein COMEC
GKQ55_RS08980	COG2131	deaminase
GKQ55_RS08985	COG1596	polysaccharide export
GKQ55_RS08985	COG1555	photosystem II stabilization
GKQ55_RS08990	COG3480	Lon protease (S16) C-terminal proteolytic domain
GKQ55_RS08995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKQ55_RS09000	COG0742	ribosomal rna small subunit methyltransferase
GKQ55_RS09005	COG4471	UPF0298 protein
GKQ55_RS09020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GKQ55_RS09025	COG0772	Belongs to the SEDS family
GKQ55_RS09030	COG4838	Belongs to the UPF0358 family
GKQ55_RS09035	COG0514	ATP-dependent DNA helicase (RecQ)
GKQ55_RS09045	COG0483	inositol monophosphate 1-phosphatase activity
GKQ55_RS09050	COG4476	Belongs to the UPF0223 family
GKQ55_RS09055	COG0038	chloride channel
GKQ55_RS09060	COG1215	transferase activity, transferring glycosyl groups
GKQ55_RS09085	COG0018	arginyl-trna synthetase
GKQ55_RS09090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKQ55_RS09095	COG0456	acetyltransferase
GKQ55_RS09105	COG1214	PFAM Peptidase M22, glycoprotease
GKQ55_RS09135	COG0546	phosphoglycolate phosphatase activity
GKQ55_RS09150	COG1682	transport, permease protein
GKQ55_RS09155	COG1134	teichoic acid transport
GKQ55_RS09155	COG1388	LysM domain
GKQ55_RS09175	COG1216	Glycosyl transferase, family 2
GKQ55_RS09180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKQ55_RS09180	COG1215	transferase activity, transferring glycosyl groups
GKQ55_RS09185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKQ55_RS09190	COG4589	Belongs to the CDS family
GKQ55_RS09195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKQ55_RS09200	COG1464	Belongs to the NlpA lipoprotein family
GKQ55_RS09205	COG2011	ABC-type metal ion transport system permease component
GKQ55_RS09210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKQ55_RS09215	COG0509	glycine decarboxylation via glycine cleavage system
GKQ55_RS09220	COG1393	Belongs to the ArsC family
GKQ55_RS09225	COG0772	Belongs to the SEDS family
GKQ55_RS09250	COG1396	sequence-specific DNA binding
GKQ55_RS09280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKQ55_RS09285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKQ55_RS09290	COG0009	L-threonylcarbamoyladenylate synthase
GKQ55_RS09295	COG2890	protein-(glutamine-N5) methyltransferase activity
GKQ55_RS09300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKQ55_RS09305	COG1435	thymidine kinase activity
GKQ55_RS09310	COG1053	succinate dehydrogenase
GKQ55_RS09315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKQ55_RS09325	COG0493	'glutamate synthase
GKQ55_RS09325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GKQ55_RS09330	COG0543	2 iron, 2 sulfur cluster binding
GKQ55_RS09335	COG0716	FMN binding
GKQ55_RS09340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GKQ55_RS09340	COG3608	succinylglutamate desuccinylase aspartoacylase
GKQ55_RS09345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKQ55_RS09370	COG0746	molybdenum cofactor guanylyltransferase activity
GKQ55_RS09380	COG3608	succinylglutamate desuccinylase aspartoacylase
GKQ55_RS09380	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GKQ55_RS09395	COG0251	oxidation-reduction process
GKQ55_RS09400	COG0549	Belongs to the carbamate kinase family
GKQ55_RS09405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKQ55_RS09410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKQ55_RS09425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GKQ55_RS09425	COG0493	'glutamate synthase
GKQ55_RS09430	COG0402	S-adenosylhomocysteine deaminase activity
GKQ55_RS09440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GKQ55_RS09445	COG3442	glutamine amidotransferase
GKQ55_RS09450	COG1957	nucleoside hydrolase
GKQ55_RS09460	COG1482	cell wall glycoprotein biosynthetic process
GKQ55_RS09475	COG1132	(ABC) transporter
GKQ55_RS09490	COG0194	GDP metabolic process
GKQ55_RS09495	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS09500	COG2190	(PTS) system
GKQ55_RS09500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS09500	COG1263	PTS System
GKQ55_RS09505	COG3711	transcriptional antiterminator
GKQ55_RS09510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKQ55_RS09515	COG0628	permease
GKQ55_RS09530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKQ55_RS09535	COG4836	Membrane
GKQ55_RS09540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GKQ55_RS09545	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKQ55_RS09550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKQ55_RS09555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKQ55_RS09560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKQ55_RS09565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKQ55_RS09570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKQ55_RS09575	COG0356	it plays a direct role in the translocation of protons across the membrane
GKQ55_RS09580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GKQ55_RS09585	COG0557	exoribonuclease II activity
GKQ55_RS09595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GKQ55_RS09600	COG2388	GCN5-related N-acetyl-transferase
GKQ55_RS09605	COG3592	Divergent 4Fe-4S mono-cluster
GKQ55_RS09615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GKQ55_RS09620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKQ55_RS09625	COG2246	polysaccharide biosynthetic process
GKQ55_RS09630	COG3942	CHAP domain
GKQ55_RS09630	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKQ55_RS09645	COG0459	protein refolding
GKQ55_RS09650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKQ55_RS09665	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKQ55_RS09670	COG0488	(ABC) transporter
GKQ55_RS09680	COG3448	diguanylate cyclase activity
GKQ55_RS09680	COG4175	Glycine betaine
GKQ55_RS09695	COG1597	lipid kinase activity
GKQ55_RS09700	COG3835	regulator
GKQ55_RS09705	COG1929	Belongs to the glycerate kinase type-1 family
GKQ55_RS09710	COG2610	gluconate transmembrane transporter activity
GKQ55_RS09715	COG0398	Pfam SNARE associated Golgi protein
GKQ55_RS09720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GKQ55_RS09725	COG1177	transmembrane transport
GKQ55_RS09730	COG1176	ABC-type spermidine putrescine transport system, permease component I
GKQ55_RS09735	COG3842	ATPase activity
GKQ55_RS09745	COG0604	alcohol dehydrogenase
GKQ55_RS09755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKQ55_RS09760	COG4684	Psort location CytoplasmicMembrane, score
GKQ55_RS09765	COG2348	transferase activity, transferring amino-acyl groups
GKQ55_RS09780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKQ55_RS09790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GKQ55_RS09800	COG3142	Participates in the control of copper homeostasis
GKQ55_RS09805	COG2239	Acts as a magnesium transporter
GKQ55_RS09810	COG0564	pseudouridine synthase activity
GKQ55_RS09815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKQ55_RS09820	COG2357	RelA SpoT domain protein
GKQ55_RS09825	COG4116	CYTH
GKQ55_RS09840	COG1164	Oligoendopeptidase f
GKQ55_RS09850	COG4862	establishment of competence for transformation
GKQ55_RS09855	COG1393	Belongs to the ArsC family
GKQ55_RS09860	COG0180	Tryptophanyl-tRNA synthetase
GKQ55_RS09865	COG1132	(ABC) transporter
GKQ55_RS09910	COG0419	ATPase involved in DNA repair
GKQ55_RS09915	COG0420	3'-5' exonuclease activity
GKQ55_RS09920	COG0204	Acyl-transferase
GKQ55_RS09925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GKQ55_RS09930	COG2827	Endonuclease containing a URI domain
GKQ55_RS09935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKQ55_RS09945	COG0494	nUDIX hydrolase
GKQ55_RS09955	COG3853	Toxic anion resistance protein (TelA)
GKQ55_RS09980	COG1194	a g-specific adenine glycosylase
GKQ55_RS09985	COG2137	regulation of response to DNA damage stimulus
GKQ55_RS09990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKQ55_RS09995	COG2261	transglycosylase associated protein
GKQ55_RS10000	COG3250	beta-galactosidase activity
GKQ55_RS10005	COG0531	amino acid
GKQ55_RS10010	COG1917	Cupin 2, conserved barrel domain protein
GKQ55_RS10010	COG2207	Transcriptional regulator
GKQ55_RS10020	COG0222	ribosome binding
GKQ55_RS10025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKQ55_RS10030	COG0081	regulation of translation
GKQ55_RS10035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKQ55_RS10040	COG0488	(ABC) transporter
GKQ55_RS10045	COG1760	l-serine dehydratase
GKQ55_RS10050	COG1760	l-serine dehydratase
GKQ55_RS10060	COG1363	Peptidase, m42
GKQ55_RS10065	COG4166	transmembrane transport
GKQ55_RS10080	COG0250	Participates in transcription elongation, termination and antitermination
GKQ55_RS10085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GKQ55_RS10090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKQ55_RS10105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GKQ55_RS10115	COG0708	Exodeoxyribonuclease III
GKQ55_RS10145	COG0095	Lipoate-protein ligase
GKQ55_RS10150	COG1234	tRNA 3'-trailer cleavage
GKQ55_RS10160	COG1363	Peptidase, m42
GKQ55_RS10165	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKQ55_RS10170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKQ55_RS10175	COG1696	Membrane protein involved in D-alanine export
GKQ55_RS10180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GKQ55_RS10190	COG0577	efflux transmembrane transporter activity
GKQ55_RS10195	COG1136	(ABC) transporter
GKQ55_RS10200	COG1328	CTP reductase activity
GKQ55_RS10205	COG0602	queuosine metabolic process
GKQ55_RS10215	COG0390	transport system, permease component
GKQ55_RS10220	COG4619	ABC transporter
GKQ55_RS10230	COG4467	Involved in initiation control of chromosome replication
GKQ55_RS10235	COG1774	PSP1 C-terminal conserved region
GKQ55_RS10240	COG0470	DNA polymerase III
GKQ55_RS10245	COG3870	Protein conserved in bacteria
GKQ55_RS10250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKQ55_RS10255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKQ55_RS10260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GKQ55_RS10270	COG1122	ATPase activity
GKQ55_RS10285	COG0477	Major facilitator Superfamily
GKQ55_RS10290	COG2814	Major facilitator Superfamily
GKQ55_RS10295	COG1733	regulation of RNA biosynthetic process
GKQ55_RS10300	COG0351	phosphomethylpyrimidine kinase
GKQ55_RS10305	COG0352	thiamine-phosphate diphosphorylase activity
GKQ55_RS10310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GKQ55_RS10320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKQ55_RS10325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKQ55_RS10330	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GKQ55_RS10335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKQ55_RS10350	COG3189	MarR family transcriptional regulator
GKQ55_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKQ55_RS10360	COG1940	carbohydrate kinase activity
GKQ55_RS10375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKQ55_RS10380	COG1073	alpha beta
GKQ55_RS10415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKQ55_RS10420	COG0768	penicillin binding
GKQ55_RS10425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKQ55_RS10430	COG1942	4-Oxalocrotonate Tautomerase
GKQ55_RS10435	COG1876	peptidase activity
GKQ55_RS10475	COG0217	transcriptional regulatory protein
GKQ55_RS10480	COG1323	Belongs to the UPF0348 family
GKQ55_RS10485	COG2226	methyltransferase
GKQ55_RS10490	COG0799	negative regulation of ribosome biogenesis
GKQ55_RS10495	COG1713	HD superfamily hydrolase involved in NAD metabolism
GKQ55_RS10500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKQ55_RS10505	COG1534	Rna-binding protein
GKQ55_RS10510	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKQ55_RS10520	COG0825	malonyl-CoA metabolic process
GKQ55_RS10525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKQ55_RS10530	COG0439	Biotin carboxylase
GKQ55_RS10535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKQ55_RS10545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKQ55_RS10555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKQ55_RS10570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKQ55_RS10575	COG1846	Transcriptional regulator
GKQ55_RS10580	COG4703	Protein of unknown function (DUF1797)
GKQ55_RS10585	COG2084	Dehydrogenase
GKQ55_RS10590	COG0438	transferase activity, transferring glycosyl groups
GKQ55_RS10635	COG1098	S1 RNA binding domain
GKQ55_RS10640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GKQ55_RS10655	COG0492	ferredoxin-NADP+ reductase activity
GKQ55_RS10665	COG0737	Belongs to the 5'-nucleotidase family
GKQ55_RS10685	COG1175	transmembrane transport
GKQ55_RS10690	COG3842	ATPase activity
GKQ55_RS10705	COG1674	ftsk spoiiie
GKQ55_RS10715	COG2946	Replication initiation factor
GKQ55_RS10745	COG0741	lytic transglycosylase activity
GKQ55_RS10745	COG0791	NLP P60 protein
GKQ55_RS10795	COG0463	Glycosyl transferase, family 2
GKQ55_RS10800	COG4841	protein insertion into membrane
GKQ55_RS10805	COG0569	domain protein
GKQ55_RS10810	COG2197	response regulator
GKQ55_RS10815	COG4585	Histidine kinase
GKQ55_RS10825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GKQ55_RS10830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKQ55_RS10840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GKQ55_RS10845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKQ55_RS10860	COG2832	Protein of unknown function (DUF454)
GKQ55_RS10875	COG1278	Cold shock
GKQ55_RS10880	COG2003	Belongs to the UPF0758 family
GKQ55_RS10885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKQ55_RS10890	COG0285	dihydrofolate synthase activity
GKQ55_RS10905	COG0525	valine-tRNA ligase activity
GKQ55_RS10910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKQ55_RS10915	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKQ55_RS10920	COG0301	tRNA thio-modification
GKQ55_RS10925	COG2252	PERMEase
GKQ55_RS10930	COG4221	oxidoreductase activity
GKQ55_RS10935	COG0110	maltose O-acetyltransferase activity
GKQ55_RS10940	COG0583	DNA-binding transcription factor activity
GKQ55_RS10945	COG4975	Glucose uptake
GKQ55_RS10950	COG1869	D-ribose catabolic process
GKQ55_RS10960	COG1609	Transcriptional regulator
GKQ55_RS10980	COG3711	transcriptional antiterminator
GKQ55_RS11005	COG1834	amidinotransferase
GKQ55_RS11010	COG1785	Belongs to the alkaline phosphatase family
GKQ55_RS11015	COG1193	negative regulation of DNA recombination
GKQ55_RS11030	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS11035	COG3715	PTS system
GKQ55_RS11040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS11070	COG0577	efflux transmembrane transporter activity
GKQ55_RS11075	COG1136	(ABC) transporter
GKQ55_RS11080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKQ55_RS11090	COG0446	pyridine nucleotide-disulphide oxidoreductase
GKQ55_RS11100	COG1937	Protein conserved in bacteria
GKQ55_RS11110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GKQ55_RS11115	COG2508	Transcriptional regulator
GKQ55_RS11120	COG3257	ureidoglycine aminohydrolase activity
GKQ55_RS11125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKQ55_RS11130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GKQ55_RS11135	COG1953	Uracil, thiamine, allantoin
GKQ55_RS11145	COG1846	Transcriptional regulator
GKQ55_RS11155	COG0659	secondary active sulfate transmembrane transporter activity
GKQ55_RS11160	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GKQ55_RS11205	COG2508	Transcriptional regulator
GKQ55_RS11215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GKQ55_RS11220	COG1304	FMN binding
GKQ55_RS11235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKQ55_RS11240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GKQ55_RS11275	COG1823	symporter activity
GKQ55_RS11280	COG5492	domain, Protein
GKQ55_RS11285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKQ55_RS11290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKQ55_RS11295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKQ55_RS11305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKQ55_RS11310	COG1363	Peptidase, m42
GKQ55_RS11320	COG4166	transmembrane transport
GKQ55_RS11325	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS11330	COG3715	PTS system
GKQ55_RS11335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKQ55_RS11340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS11355	COG3394	polysaccharide catabolic process
GKQ55_RS11365	COG0519	Catalyzes the synthesis of GMP from XMP
GKQ55_RS11395	COG3764	Sortase (surface protein transpeptidase)
GKQ55_RS11405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKQ55_RS11430	COG1185	polyribonucleotide nucleotidyltransferase activity
GKQ55_RS11435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKQ55_RS11440	COG0242	peptide deformylase activity
GKQ55_RS11460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKQ55_RS11465	COG1268	BioY protein
GKQ55_RS11490	COG4493	Belongs to the UPF0637 family
GKQ55_RS11500	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKQ55_RS11505	COG4166	transmembrane transport
GKQ55_RS11510	COG4607	ABC-type enterochelin transport system periplasmic component
GKQ55_RS11515	COG4604	ABC transporter, ATP-binding protein
GKQ55_RS11520	COG4605	iron ion homeostasis
GKQ55_RS11525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKQ55_RS11545	COG1181	Belongs to the D-alanine--D-alanine ligase family
GKQ55_RS11545	COG2918	glutathione biosynthetic process
GKQ55_RS11555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKQ55_RS11570	COG0552	protein localization to endoplasmic reticulum
GKQ55_RS11575	COG0561	phosphatase activity
GKQ55_RS11580	COG1196	nuclear chromosome segregation
GKQ55_RS11585	COG0571	ribonuclease III activity
GKQ55_RS11600	COG0601	transmembrane transport
GKQ55_RS11605	COG4608	Belongs to the ABC transporter superfamily
GKQ55_RS11615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKQ55_RS11620	COG0416	fatty acid biosynthetic process
GKQ55_RS11625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKQ55_RS11630	COG1461	Dihydroxyacetone kinase
GKQ55_RS11640	COG3279	Response regulator of the LytR AlgR family
GKQ55_RS11650	COG1668	transmembrane transport
GKQ55_RS11655	COG4152	abc transporter atp-binding protein
GKQ55_RS11660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GKQ55_RS11670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GKQ55_RS11675	COG1162	GTPase activity
GKQ55_RS11680	COG2815	serine threonine protein kinase
GKQ55_RS11680	COG0515	serine threonine protein kinase
GKQ55_RS11690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKQ55_RS11690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKQ55_RS11695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKQ55_RS11705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKQ55_RS11710	COG1758	RNA polymerase activity
GKQ55_RS11715	COG0194	GDP metabolic process
GKQ55_RS11745	COG0800	Aldolase
GKQ55_RS11750	COG1312	Catalyzes the dehydration of D-mannonate
GKQ55_RS11760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS11765	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS11775	COG0371	Dehydrogenase
GKQ55_RS11785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GKQ55_RS11790	COG1737	Transcriptional regulator
GKQ55_RS11800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKQ55_RS11840	COG1426	Protein conserved in bacteria
GKQ55_RS11845	COG0612	Peptidase, M16
GKQ55_RS11850	COG0612	Peptidase, M16
GKQ55_RS11855	COG1970	mechanosensitive ion channel activity
GKQ55_RS11865	COG2188	Transcriptional regulator
GKQ55_RS11870	COG1554	hydrolase, family 65, central catalytic
GKQ55_RS11875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKQ55_RS11895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKQ55_RS11905	COG0424	maF-like protein
GKQ55_RS11910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKQ55_RS11915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKQ55_RS11920	COG4550	Control of competence regulator ComK, YlbF/YmcA
GKQ55_RS11925	COG1692	metallophosphoesterase
GKQ55_RS11930	COG1418	mRNA catabolic process
GKQ55_RS11935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKQ55_RS11940	COG1546	Belongs to the CinA family
GKQ55_RS11940	COG1058	Belongs to the CinA family
GKQ55_RS11950	COG2910	NAD(P)H-binding
GKQ55_RS11955	COG1959	2 iron, 2 sulfur cluster binding
GKQ55_RS11970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GKQ55_RS12030	COG1335	isochorismatase
GKQ55_RS12035	COG1346	cytolysis
GKQ55_RS12045	COG3279	Response regulator of the LytR AlgR family
GKQ55_RS12050	COG3275	phosphorelay sensor kinase activity
GKQ55_RS12060	COG2011	ABC-type metal ion transport system permease component
GKQ55_RS12075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKQ55_RS12080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKQ55_RS12095	COG3443	Belongs to the bacterial solute-binding protein 9 family
GKQ55_RS12095	COG0803	Belongs to the bacterial solute-binding protein 9 family
GKQ55_RS12100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKQ55_RS12105	COG0842	Transport permease protein
GKQ55_RS12110	COG1131	(ABC) transporter
GKQ55_RS12125	COG3715	PTS system
GKQ55_RS12130	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS12150	COG1368	sulfuric ester hydrolase activity
GKQ55_RS12155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKQ55_RS12160	COG0640	Transcriptional regulator
GKQ55_RS12165	COG2217	Heavy metal translocating P-type atpase
GKQ55_RS12185	COG0582	viral genome integration into host DNA
GKQ55_RS12190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GKQ55_RS12195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKQ55_RS12200	COG0783	Belongs to the Dps family
GKQ55_RS12210	COG1070	Carbohydrate kinase
GKQ55_RS12215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GKQ55_RS12220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKQ55_RS12225	COG0085	RNA polymerase activity
GKQ55_RS12250	COG3397	chitin binding
GKQ55_RS12255	COG1316	TRANSCRIPTIONal
GKQ55_RS12295	COG1575	Belongs to the MenA family. Type 1 subfamily
GKQ55_RS12305	COG4939	FMN-binding domain protein
GKQ55_RS12325	COG0142	geranyltranstransferase activity
GKQ55_RS12330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKQ55_RS12335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKQ55_RS12340	COG0302	gtp cyclohydrolase
GKQ55_RS12350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKQ55_RS12355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKQ55_RS12390	COG2508	Transcriptional regulator
GKQ55_RS12390	COG2508	Transcriptional regulator
GKQ55_RS12410	COG0542	response to heat
GKQ55_RS12415	COG4463	regulation of RNA biosynthetic process
GKQ55_RS12420	COG0626	cystathionine gamma-synthase activity
GKQ55_RS12425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS12430	COG1737	Transcriptional regulator
GKQ55_RS12490	COG0745	RESPONSE REGULATOR receiver
GKQ55_RS12500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKQ55_RS12505	COG0517	IMP dehydrogenase activity
GKQ55_RS12505	COG0516	GMP reductase activity
GKQ55_RS12520	COG0012	GTP binding
GKQ55_RS12525	COG4481	Protein conserved in bacteria
GKQ55_RS12530	COG1475	DNA binding
GKQ55_RS12535	COG1192	Involved in chromosome partitioning
GKQ55_RS12540	COG0357	Ribosomal RNA small subunit methyltransferase G
GKQ55_RS12565	COG3732	PTS system glucitol sorbitol-specific
GKQ55_RS12570	COG3730	PTS system glucitol sorbitol-specific
GKQ55_RS12590	COG0445	tRNA wobble uridine modification
GKQ55_RS12595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKQ55_RS12605	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GKQ55_RS12635	COG3052	prosthetic group binding
GKQ55_RS12640	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GKQ55_RS12645	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GKQ55_RS12650	COG0511	ligase activity, forming carbon-carbon bonds
GKQ55_RS12660	COG2851	Citrate transporter
GKQ55_RS12680	COG0706	membrane insertase activity
GKQ55_RS12685	COG0594	ribonuclease P activity
GKQ55_RS12690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GKQ55_RS12695	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKQ55_RS12700	COG0592	DNA-directed DNA polymerase activity
GKQ55_RS12705	COG2501	S4 domain
GKQ55_RS12710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKQ55_RS12715	COG0187	DNA topoisomerase II activity
GKQ55_RS12725	COG0360	Binds together with S18 to 16S ribosomal RNA
GKQ55_RS12730	COG0629	single-stranded DNA binding
GKQ55_RS12735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKQ55_RS12745	COG0359	binds to the 23S rRNA
GKQ55_RS12750	COG0305	Participates in initiation and elongation during chromosome replication
GKQ55_RS12755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKQ55_RS12765	COG0488	(ABC) transporter
GKQ55_RS12770	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GKQ55_RS12770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GKQ55_RS12775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS12775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GKQ55_RS12785	COG3715	PTS system
GKQ55_RS12790	COG3716	PTS system mannose fructose sorbose family IID component
GKQ55_RS12810	COG1737	Transcriptional regulator
GKQ55_RS12815	COG1263	PTS System
GKQ55_RS12815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS12820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GKQ55_RS12825	COG0251	oxidation-reduction process
GKQ55_RS12830	COG0392	lysyltransferase activity
GKQ55_RS12830	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKQ55_RS12860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKQ55_RS12865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKQ55_RS12870	COG0756	dUTP diphosphatase activity
GKQ55_RS12880	COG4956	integral membrane protein (PIN domain superfamily)
GKQ55_RS12885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GKQ55_RS12890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKQ55_RS12895	COG1045	serine acetyltransferase
GKQ55_RS12900	COG0215	cysteine-tRNA ligase activity
GKQ55_RS12905	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKQ55_RS12910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKQ55_RS12915	COG3688	RNA-binding protein containing a PIN domain
GKQ55_RS12925	COG4466	Protein conserved in bacteria
GKQ55_RS12930	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKQ55_RS12935	COG3443	Belongs to the bacterial solute-binding protein 9 family
GKQ55_RS12935	COG0803	Belongs to the bacterial solute-binding protein 9 family
GKQ55_RS12940	COG1121	(ABC) transporter
GKQ55_RS12945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKQ55_RS12950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKQ55_RS12955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKQ55_RS12960	COG0737	Belongs to the 5'-nucleotidase family
GKQ55_RS12965	COG4166	transmembrane transport
GKQ55_RS12970	COG4224	UPF0291 protein
GKQ55_RS12975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKQ55_RS12980	COG0632	four-way junction helicase activity
GKQ55_RS12985	COG2255	four-way junction helicase activity
GKQ55_RS12995	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GKQ55_RS13000	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GKQ55_RS13000	COG3408	Glycogen debranching enzyme
GKQ55_RS13010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKQ55_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
GKQ55_RS13040	COG2261	transglycosylase associated protein
GKQ55_RS13045	COG2814	Major facilitator Superfamily
GKQ55_RS13070	COG1597	lipid kinase activity
GKQ55_RS13090	COG2116	formate transmembrane transporter activity
GKQ55_RS13100	COG2964	Protein conserved in bacteria
GKQ55_RS13110	COG1760	l-serine dehydratase
GKQ55_RS13115	COG1760	l-serine dehydratase
GKQ55_RS13120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKQ55_RS13130	COG1438	arginine binding
GKQ55_RS13135	COG1438	arginine binding
GKQ55_RS13140	COG2235	arginine
GKQ55_RS13145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKQ55_RS13150	COG0549	Belongs to the carbamate kinase family
GKQ55_RS13160	COG1288	antiporter activity
GKQ55_RS13170	COG0640	Transcriptional regulator
GKQ55_RS13175	COG0604	alcohol dehydrogenase
GKQ55_RS13195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKQ55_RS13220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GKQ55_RS13220	COG0519	Catalyzes the synthesis of GMP from XMP
GKQ55_RS13225	COG1072	(Pantothenic acid kinase))
GKQ55_RS13235	COG2813	Specifically methylates the guanine in position
GKQ55_RS13240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKQ55_RS13250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GKQ55_RS13255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKQ55_RS13260	COG0295	cytidine deaminase activity
GKQ55_RS13265	COG1744	ABC transporter substrate-binding protein PnrA-like
GKQ55_RS13270	COG1744	ABC transporter substrate-binding protein PnrA-like
GKQ55_RS13295	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKQ55_RS13310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GKQ55_RS13315	COG1120	ATPase activity
GKQ55_RS13320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKQ55_RS13325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKQ55_RS13330	COG1979	alcohol dehydrogenase
GKQ55_RS13335	COG0588	phosphoglycerate mutase activity
GKQ55_RS13340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GKQ55_RS13345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKQ55_RS13350	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKQ55_RS13355	COG0049	tRNA binding
GKQ55_RS13360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKQ55_RS13365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKQ55_RS13370	COG0351	phosphomethylpyrimidine kinase
GKQ55_RS13375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GKQ55_RS13380	COG0051	transcription antitermination factor activity, RNA binding
GKQ55_RS13385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKQ55_RS13390	COG0088	Forms part of the polypeptide exit tunnel
GKQ55_RS13395	COG0089	rRNA binding
GKQ55_RS13400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKQ55_RS13405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKQ55_RS13410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKQ55_RS13415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKQ55_RS13420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKQ55_RS13425	COG0255	Belongs to the universal ribosomal protein uL29 family
GKQ55_RS13430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKQ55_RS13435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKQ55_RS13440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKQ55_RS13445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKQ55_RS13450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKQ55_RS13455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKQ55_RS13460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKQ55_RS13465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKQ55_RS13470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKQ55_RS13475	COG1841	ribosomal large subunit assembly
GKQ55_RS13480	COG0200	Binds to the 23S rRNA
GKQ55_RS13485	COG0201	protein transport
GKQ55_RS13490	COG0563	adenylate kinase activity
GKQ55_RS13495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKQ55_RS13500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GKQ55_RS13505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKQ55_RS13510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKQ55_RS13515	COG0202	RNA polymerase activity
GKQ55_RS13520	COG0203	ribosomal protein L17
GKQ55_RS13530	COG1473	amidohydrolase
GKQ55_RS13535	COG1122	ATPase activity
GKQ55_RS13540	COG1122	ATPase activity
GKQ55_RS13555	COG0393	Putative heavy-metal-binding
GKQ55_RS13560	COG1114	Component of the transport system for branched-chain amino acids
GKQ55_RS13575	COG1126	abc transporter atp-binding protein
GKQ55_RS13580	COG0765	amino acid transport
GKQ55_RS13590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKQ55_RS13595	COG0110	maltose O-acetyltransferase activity
GKQ55_RS13600	COG1827	regulation of RNA biosynthetic process
GKQ55_RS13605	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKQ55_RS13605	COG3942	CHAP domain
GKQ55_RS13615	COG0039	L-malate dehydrogenase activity
GKQ55_RS13620	COG0193	aminoacyl-tRNA hydrolase activity
GKQ55_RS13625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKQ55_RS13630	COG2244	polysaccharide biosynthetic process
GKQ55_RS13635	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GKQ55_RS13645	COG1098	S1 RNA binding domain
GKQ55_RS13650	COG0037	tRNA processing
GKQ55_RS13660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKQ55_RS13665	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKQ55_RS13670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKQ55_RS13675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GKQ55_RS13820	COG3711	transcriptional antiterminator
GKQ55_RS13825	COG1263	PTS System
GKQ55_RS13825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GKQ55_RS13825	COG2190	(PTS) system
GKQ55_RS13830	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS13835	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS13845	COG0596	Alpha beta hydrolase
GKQ55_RS13850	COG2169	Transcriptional regulator
GKQ55_RS13855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKQ55_RS13860	COG0519	Catalyzes the synthesis of GMP from XMP
GKQ55_RS13865	COG1418	mRNA catabolic process
GKQ55_RS13880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GKQ55_RS13885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKQ55_RS13890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKQ55_RS13895	COG0167	dihydroorotate dehydrogenase activity
GKQ55_RS13905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKQ55_RS13915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GKQ55_RS13920	COG0626	cystathionine gamma-synthase activity
GKQ55_RS13925	COG2723	6-phospho-beta-galactosidase activity
GKQ55_RS13930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKQ55_RS13940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKQ55_RS13945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKQ55_RS13960	COG2217	Heavy metal translocating P-type atpase
GKQ55_RS13975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GKQ55_RS13980	COG3579	cysteine-type endopeptidase activity
GKQ55_RS13985	COG0582	viral genome integration into host DNA
GKQ55_RS14000	COG1396	sequence-specific DNA binding
GKQ55_RS14130	COG2369	cell adhesion