locus-tag	class	description
EFD32_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFD32_RS00010	COG0592	DNA-directed DNA polymerase activity
EFD32_RS00015	COG2501	S4 domain
EFD32_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFD32_RS00025	COG0187	DNA topoisomerase II activity
EFD32_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
EFD32_RS00040	COG0629	single-stranded DNA binding
EFD32_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFD32_RS00055	COG0359	binds to the 23S rRNA
EFD32_RS00060	COG2190	(PTS) system
EFD32_RS00060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS00060	COG1263	PTS System
EFD32_RS00065	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS00070	COG3711	transcriptional antiterminator
EFD32_RS00075	COG0305	Participates in initiation and elongation during chromosome replication
EFD32_RS00080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFD32_RS00095	COG0488	(ABC) transporter
EFD32_RS00100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EFD32_RS00100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EFD32_RS00105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS00105	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS00115	COG3715	PTS system
EFD32_RS00120	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS00140	COG1737	Transcriptional regulator
EFD32_RS00145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS00145	COG1263	PTS System
EFD32_RS00150	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EFD32_RS00155	COG0251	oxidation-reduction process
EFD32_RS00160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFD32_RS00160	COG0392	lysyltransferase activity
EFD32_RS00190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFD32_RS00195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFD32_RS00200	COG0756	dUTP diphosphatase activity
EFD32_RS00210	COG4956	integral membrane protein (PIN domain superfamily)
EFD32_RS00215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EFD32_RS00220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFD32_RS00225	COG1045	serine acetyltransferase
EFD32_RS00230	COG0215	cysteine-tRNA ligase activity
EFD32_RS00235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFD32_RS00240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFD32_RS00245	COG3688	RNA-binding protein containing a PIN domain
EFD32_RS00255	COG4466	Protein conserved in bacteria
EFD32_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EFD32_RS00265	COG0803	Belongs to the bacterial solute-binding protein 9 family
EFD32_RS00265	COG3443	Belongs to the bacterial solute-binding protein 9 family
EFD32_RS00270	COG1121	(ABC) transporter
EFD32_RS00275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EFD32_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFD32_RS00285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFD32_RS00290	COG0737	Belongs to the 5'-nucleotidase family
EFD32_RS00305	COG4166	transmembrane transport
EFD32_RS00310	COG4224	UPF0291 protein
EFD32_RS00315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFD32_RS00325	COG0632	four-way junction helicase activity
EFD32_RS00330	COG2255	four-way junction helicase activity
EFD32_RS00340	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EFD32_RS00345	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EFD32_RS00345	COG3408	Glycogen debranching enzyme
EFD32_RS00355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EFD32_RS00365	COG1028	Short-chain dehydrogenase reductase Sdr
EFD32_RS00390	COG2261	transglycosylase associated protein
EFD32_RS00395	COG2814	Major facilitator Superfamily
EFD32_RS00420	COG1597	lipid kinase activity
EFD32_RS00440	COG2116	formate transmembrane transporter activity
EFD32_RS00450	COG2964	Protein conserved in bacteria
EFD32_RS00460	COG1760	l-serine dehydratase
EFD32_RS00465	COG1760	l-serine dehydratase
EFD32_RS00470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFD32_RS00485	COG1438	arginine binding
EFD32_RS00490	COG2235	arginine
EFD32_RS00495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFD32_RS00500	COG0549	Belongs to the carbamate kinase family
EFD32_RS00510	COG1288	antiporter activity
EFD32_RS00520	COG0640	Transcriptional regulator
EFD32_RS00525	COG0604	alcohol dehydrogenase
EFD32_RS00535	COG0251	oxidation-reduction process
EFD32_RS00545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EFD32_RS00550	COG2423	ornithine cyclodeaminase activity
EFD32_RS00590	COG0519	Catalyzes the synthesis of GMP from XMP
EFD32_RS00590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EFD32_RS00595	COG1072	(Pantothenic acid kinase))
EFD32_RS00605	COG2813	Specifically methylates the guanine in position
EFD32_RS00610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EFD32_RS00615	COG1609	Transcriptional regulator
EFD32_RS00620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EFD32_RS00625	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFD32_RS00630	COG0295	cytidine deaminase activity
EFD32_RS00635	COG1744	ABC transporter substrate-binding protein PnrA-like
EFD32_RS00640	COG1744	ABC transporter substrate-binding protein PnrA-like
EFD32_RS00645	COG3845	ABC transporter
EFD32_RS00650	COG4603	Belongs to the binding-protein-dependent transport system permease family
EFD32_RS00655	COG1079	Belongs to the binding-protein-dependent transport system permease family
EFD32_RS00665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EFD32_RS00680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EFD32_RS00685	COG1120	ATPase activity
EFD32_RS00690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD32_RS00695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD32_RS00700	COG1979	alcohol dehydrogenase
EFD32_RS00705	COG0588	phosphoglycerate mutase activity
EFD32_RS00710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EFD32_RS00715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EFD32_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFD32_RS00725	COG0049	tRNA binding
EFD32_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFD32_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFD32_RS00740	COG0351	phosphomethylpyrimidine kinase
EFD32_RS00745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EFD32_RS00750	COG0051	transcription antitermination factor activity, RNA binding
EFD32_RS00755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFD32_RS00760	COG0088	Forms part of the polypeptide exit tunnel
EFD32_RS00765	COG0089	rRNA binding
EFD32_RS00770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFD32_RS00775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFD32_RS00780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFD32_RS00785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFD32_RS00790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFD32_RS00795	COG0255	Belongs to the universal ribosomal protein uL29 family
EFD32_RS00800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFD32_RS00805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFD32_RS00810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFD32_RS00815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFD32_RS00820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFD32_RS00825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFD32_RS00830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFD32_RS00835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFD32_RS00840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFD32_RS00845	COG1841	ribosomal large subunit assembly
EFD32_RS00850	COG0200	Binds to the 23S rRNA
EFD32_RS00855	COG0201	protein transport
EFD32_RS00860	COG0563	adenylate kinase activity
EFD32_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFD32_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EFD32_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFD32_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFD32_RS00885	COG0202	RNA polymerase activity
EFD32_RS00890	COG0203	ribosomal protein L17
EFD32_RS00905	COG1473	amidohydrolase
EFD32_RS00910	COG1122	ATPase activity
EFD32_RS00915	COG1122	ATPase activity
EFD32_RS00930	COG0393	Putative heavy-metal-binding
EFD32_RS00935	COG1114	Component of the transport system for branched-chain amino acids
EFD32_RS00950	COG1126	abc transporter atp-binding protein
EFD32_RS00955	COG0765	amino acid transport
EFD32_RS00965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EFD32_RS00970	COG0110	maltose O-acetyltransferase activity
EFD32_RS00975	COG1827	regulation of RNA biosynthetic process
EFD32_RS00980	COG3942	CHAP domain
EFD32_RS00980	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS00990	COG0039	L-malate dehydrogenase activity
EFD32_RS00995	COG0193	aminoacyl-tRNA hydrolase activity
EFD32_RS01000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFD32_RS01005	COG2244	polysaccharide biosynthetic process
EFD32_RS01010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EFD32_RS01025	COG1098	S1 RNA binding domain
EFD32_RS01030	COG0037	tRNA processing
EFD32_RS01035	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EFD32_RS01040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFD32_RS01045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFD32_RS01050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFD32_RS01055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EFD32_RS01200	COG3711	transcriptional antiterminator
EFD32_RS01205	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS01210	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS01220	COG0596	Alpha beta hydrolase
EFD32_RS01225	COG2169	Transcriptional regulator
EFD32_RS01230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFD32_RS01235	COG0519	Catalyzes the synthesis of GMP from XMP
EFD32_RS01240	COG1418	mRNA catabolic process
EFD32_RS01255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EFD32_RS01260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EFD32_RS01265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EFD32_RS01270	COG0167	dihydroorotate dehydrogenase activity
EFD32_RS01280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFD32_RS01290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EFD32_RS01295	COG0626	cystathionine gamma-synthase activity
EFD32_RS01300	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS01305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS01315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFD32_RS01320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EFD32_RS01335	COG2217	Heavy metal translocating P-type atpase
EFD32_RS01350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EFD32_RS01355	COG3579	cysteine-type endopeptidase activity
EFD32_RS01360	COG0582	viral genome integration into host DNA
EFD32_RS01375	COG1396	sequence-specific DNA binding
EFD32_RS01520	COG2369	cell adhesion
EFD32_RS01620	COG1388	LysM domain
EFD32_RS01620	COG3942	CHAP domain
EFD32_RS01630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFD32_RS01635	COG0346	lactoylglutathione lyase activity
EFD32_RS01640	COG2076	Multidrug Resistance protein
EFD32_RS01645	COG2076	Multidrug Resistance protein
EFD32_RS01650	COG3469	chitinase activity
EFD32_RS01655	COG3397	chitin binding
EFD32_RS01665	COG1801	Protein of unknown function DUF72
EFD32_RS01675	COG0527	aspartate kinase activity
EFD32_RS01680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EFD32_RS01685	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFD32_RS01690	COG1104	cysteine desulfurase activity
EFD32_RS01695	COG0745	RESPONSE REGULATOR receiver
EFD32_RS01700	COG5002	protein histidine kinase activity
EFD32_RS01720	COG0666	response to abiotic stimulus
EFD32_RS01745	COG3835	regulator
EFD32_RS01750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EFD32_RS01755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EFD32_RS01770	COG0549	Belongs to the carbamate kinase family
EFD32_RS01780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EFD32_RS01810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EFD32_RS01815	COG0628	permease
EFD32_RS01840	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EFD32_RS01845	COG1757	Na H antiporter
EFD32_RS01850	COG1846	Transcriptional regulator
EFD32_RS01855	COG0778	Nitroreductase
EFD32_RS01860	COG0561	phosphatase activity
EFD32_RS01865	COG2213	PTS system mannitol-specific
EFD32_RS01870	COG3711	transcriptional antiterminator
EFD32_RS01875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS01885	COG2213	PTS system mannitol-specific
EFD32_RS01890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS01895	COG0246	Mannitol dehydrogenase
EFD32_RS01900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EFD32_RS01915	COG1136	(ABC) transporter
EFD32_RS01915	COG0577	efflux transmembrane transporter activity
EFD32_RS01920	COG0577	efflux transmembrane transporter activity
EFD32_RS01940	COG2814	Major facilitator Superfamily
EFD32_RS01950	COG1414	Transcriptional regulator
EFD32_RS01955	COG0800	Aldolase
EFD32_RS01965	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EFD32_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
EFD32_RS01975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EFD32_RS02000	COG1070	Carbohydrate kinase
EFD32_RS02005	COG4806	L-rhamnose isomerase
EFD32_RS02010	COG0235	Class ii aldolase
EFD32_RS02015	COG3254	rhamnose metabolic process
EFD32_RS02035	COG3104	oligopeptide transport
EFD32_RS02045	COG3942	CHAP domain
EFD32_RS02045	COG1388	LysM domain
EFD32_RS02055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EFD32_RS02060	COG0318	PFAM AMP-dependent synthetase and ligase
EFD32_RS02065	COG1169	isochorismate synthase
EFD32_RS02070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EFD32_RS02075	COG2267	carboxylic ester hydrolase activity
EFD32_RS02080	COG4948	Mandelate Racemase Muconate Lactonizing
EFD32_RS02085	COG0363	glucosamine-6-phosphate deaminase activity
EFD32_RS02090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EFD32_RS02095	COG1764	response to oxidative stress
EFD32_RS02110	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS02115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS02125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EFD32_RS02130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EFD32_RS02145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EFD32_RS02150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EFD32_RS02155	COG1316	TRANSCRIPTIONal
EFD32_RS02160	COG0363	glucosamine-6-phosphate deaminase activity
EFD32_RS02165	COG1285	pathogenesis
EFD32_RS02185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFD32_RS02190	COG1780	Probably involved in ribonucleotide reductase function
EFD32_RS02195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EFD32_RS02215	COG0582	viral genome integration into host DNA
EFD32_RS02240	COG1191	sigma factor activity
EFD32_RS02260	COG2801	Transposase and inactivated derivatives
EFD32_RS02270	COG1192	Involved in chromosome partitioning
EFD32_RS02375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EFD32_RS02425	COG0656	L-ascorbic acid biosynthetic process
EFD32_RS02435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFD32_RS02450	COG1113	amino acid transport
EFD32_RS02455	COG1757	Na H antiporter
EFD32_RS02470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EFD32_RS02480	COG0039	L-malate dehydrogenase activity
EFD32_RS02495	COG0583	DNA-binding transcription factor activity
EFD32_RS02510	COG1733	regulation of RNA biosynthetic process
EFD32_RS02515	COG0778	Nitroreductase
EFD32_RS02520	COG0095	Lipoate-protein ligase
EFD32_RS02540	COG1609	Transcriptional regulator
EFD32_RS02550	COG2514	catechol 2,3-dioxygenase activity
EFD32_RS02555	COG1349	DNA-binding transcription factor activity
EFD32_RS02570	COG0534	Mate efflux family protein
EFD32_RS02585	COG0217	transcriptional regulatory protein
EFD32_RS02600	COG0346	lactoylglutathione lyase activity
EFD32_RS02615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFD32_RS02620	COG2244	polysaccharide biosynthetic process
EFD32_RS02625	COG1187	pseudouridine synthase activity
EFD32_RS02640	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EFD32_RS02645	COG1518	maintenance of DNA repeat elements
EFD32_RS02650	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFD32_RS02665	COG1125	glycine betaine transport
EFD32_RS02665	COG0517	IMP dehydrogenase activity
EFD32_RS02670	COG1732	Glycine betaine
EFD32_RS02675	COG1438	arginine binding
EFD32_RS02680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFD32_RS02690	COG0564	pseudouridine synthase activity
EFD32_RS02695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EFD32_RS02700	COG3679	Belongs to the UPF0342 family
EFD32_RS02715	COG3481	metal-dependent phosphohydrolase, HD sub domain
EFD32_RS02720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EFD32_RS02730	COG0537	adenosine 5'-monophosphoramidase activity
EFD32_RS02735	COG1131	(ABC) transporter
EFD32_RS02740	COG4473	ABC transporter
EFD32_RS02745	COG0510	thiamine kinase activity
EFD32_RS02750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EFD32_RS02765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS02765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS02765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS02775	COG3684	Belongs to the aldolase LacD family
EFD32_RS02780	COG3557	Belongs to the UPF0374 family
EFD32_RS02790	COG0628	permease
EFD32_RS02795	COG1253	flavin adenine dinucleotide binding
EFD32_RS02800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EFD32_RS02825	COG0542	response to heat
EFD32_RS02835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS02840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFD32_RS02860	COG0544	peptidyl-prolyl cis-trans isomerase activity
EFD32_RS02870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS02870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS02870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS02875	COG1105	Belongs to the carbohydrate kinase PfkB family
EFD32_RS02880	COG1349	DNA-binding transcription factor activity
EFD32_RS02890	COG0210	DNA helicase
EFD32_RS02895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFD32_RS02905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFD32_RS02910	COG0154	amidase activity
EFD32_RS02915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFD32_RS02920	COG1597	lipid kinase activity
EFD32_RS02925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFD32_RS02940	COG2197	response regulator
EFD32_RS02945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFD32_RS02950	COG0531	amino acid
EFD32_RS02955	COG2957	Belongs to the agmatine deiminase family
EFD32_RS02960	COG0549	Belongs to the carbamate kinase family
EFD32_RS02965	COG0154	amidase activity
EFD32_RS02980	COG1428	Deoxynucleoside kinase
EFD32_RS03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EFD32_RS03020	COG1054	Belongs to the UPF0176 family
EFD32_RS03065	COG2217	Heavy metal translocating P-type atpase
EFD32_RS03070	COG1285	pathogenesis
EFD32_RS03080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EFD32_RS03085	COG0556	nucleotide-excision repair
EFD32_RS03090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EFD32_RS03100	COG1660	Displays ATPase and GTPase activities
EFD32_RS03110	COG1481	regulation of sporulation
EFD32_RS03125	COG0740	serine-type endopeptidase activity
EFD32_RS03155	COG0584	glycerophosphoryl diester phosphodiesterase
EFD32_RS03160	COG2816	NAD+ diphosphatase activity
EFD32_RS03165	COG1278	Cold shock
EFD32_RS03175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EFD32_RS03180	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EFD32_RS03180	COG2755	lipolytic protein G-D-S-L family
EFD32_RS03185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFD32_RS03190	COG0477	Major facilitator Superfamily
EFD32_RS03205	COG1132	(ABC) transporter
EFD32_RS03210	COG1132	(ABC) transporter
EFD32_RS03220	COG1309	transcriptional regulator
EFD32_RS03225	COG0577	efflux transmembrane transporter activity
EFD32_RS03230	COG1136	(ABC) transporter
EFD32_RS03235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EFD32_RS03240	COG1242	4 iron, 4 sulfur cluster binding
EFD32_RS03245	COG0671	phosphoesterase, PA-phosphatase related
EFD32_RS03260	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS03260	COG1388	LysM domain
EFD32_RS03265	COG0495	leucyl-tRNA aminoacylation
EFD32_RS03285	COG3177	Filamentation induced by cAMP protein fic
EFD32_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EFD32_RS03295	COG1126	abc transporter atp-binding protein
EFD32_RS03300	COG0765	amino acid transport
EFD32_RS03305	COG4166	transmembrane transport
EFD32_RS03325	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EFD32_RS03335	COG2188	Transcriptional regulator
EFD32_RS03340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS03340	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS03365	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EFD32_RS03370	COG1187	pseudouridine synthase activity
EFD32_RS03375	COG1011	Hydrolase
EFD32_RS03390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EFD32_RS03415	COG0673	inositol 2-dehydrogenase activity
EFD32_RS03420	COG3711	transcriptional antiterminator
EFD32_RS03450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS03465	COG3964	amidohydrolase
EFD32_RS03485	COG0187	DNA topoisomerase II activity
EFD32_RS03490	COG1671	Belongs to the UPF0178 family
EFD32_RS03495	COG1181	Belongs to the D-alanine--D-alanine ligase family
EFD32_RS03500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EFD32_RS03515	COG0736	holo-[acyl-carrier-protein] synthase activity
EFD32_RS03520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFD32_RS03525	COG2337	Toxic component of a toxin-antitoxin (TA) module
EFD32_RS03555	COG2365	Tyrosine phosphatase family
EFD32_RS03575	COG0531	amino acid
EFD32_RS03585	COG1174	glycine betaine transport
EFD32_RS03605	COG0346	lactoylglutathione lyase activity
EFD32_RS03610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EFD32_RS03625	COG3158	transport of potassium into the cell
EFD32_RS03635	COG2217	Heavy metal translocating P-type atpase
EFD32_RS03645	COG4989	oxidoreductase activity
EFD32_RS03650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFD32_RS03650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFD32_RS03655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EFD32_RS03660	COG0237	dephospho-CoA kinase activity
EFD32_RS03665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFD32_RS03670	COG3611	Membrane attachment protein
EFD32_RS03675	COG1484	DNA-dependent DNA replication
EFD32_RS03700	COG1215	transferase activity, transferring glycosyl groups
EFD32_RS03725	COG1126	abc transporter atp-binding protein
EFD32_RS03730	COG0765	amino acid transport
EFD32_RS03735	COG0371	Dehydrogenase
EFD32_RS03740	COG0343	queuine tRNA-ribosyltransferase activity
EFD32_RS03745	COG1862	Preprotein translocase
EFD32_RS03755	COG1012	belongs to the aldehyde dehydrogenase family
EFD32_RS03755	COG1454	alcohol dehydrogenase
EFD32_RS03760	COG1304	FMN binding
EFD32_RS03790	COG4166	transmembrane transport
EFD32_RS03800	COG0601	transmembrane transport
EFD32_RS03805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFD32_RS03810	COG0444	Belongs to the ABC transporter superfamily
EFD32_RS03815	COG4608	Belongs to the ABC transporter superfamily
EFD32_RS03825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFD32_RS03830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EFD32_RS03835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFD32_RS03845	COG3759	membrane
EFD32_RS03855	COG0456	acetyltransferase
EFD32_RS03855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFD32_RS03860	COG0659	secondary active sulfate transmembrane transporter activity
EFD32_RS03865	COG2855	membrane
EFD32_RS03885	COG0745	RESPONSE REGULATOR receiver
EFD32_RS03890	COG2205	protein histidine kinase activity
EFD32_RS03895	COG4975	Glucose uptake
EFD32_RS03900	COG0531	amino acid
EFD32_RS03905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFD32_RS03905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFD32_RS03920	COG3973	AAA domain
EFD32_RS03925	COG0084	hydrolase, TatD family'
EFD32_RS03930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFD32_RS03935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EFD32_RS03945	COG3842	ATPase activity
EFD32_RS03950	COG1803	Methylglyoxal synthase
EFD32_RS03955	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFD32_RS03960	COG1132	(ABC) transporter
EFD32_RS03975	COG3584	3D domain protein
EFD32_RS03990	COG0561	phosphatase activity
EFD32_RS03995	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFD32_RS04000	COG0280	phosphate acetyltransferase
EFD32_RS04005	COG0802	atpase or kinase
EFD32_RS04020	COG1609	Transcriptional regulator
EFD32_RS04025	COG2017	converts alpha-aldose to the beta-anomer
EFD32_RS04030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EFD32_RS04040	COG2190	(PTS) system
EFD32_RS04040	COG1263	PTS System
EFD32_RS04040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS04050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFD32_RS04120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EFD32_RS04130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EFD32_RS04135	COG3223	Belongs to the PsiE family
EFD32_RS04140	COG1408	metallophosphoesterase
EFD32_RS04145	COG0006	proline dipeptidase activity
EFD32_RS04150	COG1694	Mazg nucleotide pyrophosphohydrolase
EFD32_RS04155	COG1302	Protein conserved in bacteria
EFD32_RS04160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFD32_RS04165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFD32_RS04170	COG1570	exodeoxyribonuclease VII activity
EFD32_RS04175	COG1722	exodeoxyribonuclease VII activity
EFD32_RS04180	COG0142	geranyltranstransferase activity
EFD32_RS04185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EFD32_RS04190	COG1438	arginine binding
EFD32_RS04195	COG0497	DNA recombination
EFD32_RS04215	COG2001	Belongs to the MraZ family
EFD32_RS04220	COG0275	rRNA processing
EFD32_RS04230	COG0768	penicillin binding
EFD32_RS04235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFD32_RS04240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFD32_RS04245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFD32_RS04255	COG0849	cell division
EFD32_RS04260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFD32_RS04265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFD32_RS04270	COG1799	cell septum assembly
EFD32_RS04275	COG0762	integral membrane protein
EFD32_RS04280	COG2302	S4 RNA-binding domain
EFD32_RS04285	COG3599	regulation of cell shape
EFD32_RS04290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFD32_RS04295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EFD32_RS04315	COG0673	inositol 2-dehydrogenase activity
EFD32_RS04325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EFD32_RS04325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EFD32_RS04330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS04335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS04355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS04360	COG1447	Phosphotransferase system cellobiose-specific component IIA
EFD32_RS04365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS04370	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS04395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFD32_RS04395	COG0574	Belongs to the PEP-utilizing enzyme family
EFD32_RS04400	COG0517	IMP dehydrogenase activity
EFD32_RS04405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EFD32_RS04410	COG0392	lysyltransferase activity
EFD32_RS04410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFD32_RS04450	COG0105	UTP biosynthetic process
EFD32_RS04475	COG2252	PERMEase
EFD32_RS04480	COG2814	Major facilitator Superfamily
EFD32_RS04490	COG0587	DNA-directed DNA polymerase activity
EFD32_RS04495	COG0205	6-phosphofructokinase activity
EFD32_RS04510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EFD32_RS04515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFD32_RS04520	COG0745	RESPONSE REGULATOR receiver
EFD32_RS04525	COG5002	protein histidine kinase activity
EFD32_RS04615	COG1116	anion transmembrane transporter activity
EFD32_RS04620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EFD32_RS04625	COG0572	uridine kinase
EFD32_RS04635	COG1914	H( )-stimulated, divalent metal cation uptake system
EFD32_RS04645	COG2508	Transcriptional regulator
EFD32_RS04650	COG4166	transmembrane transport
EFD32_RS04655	COG0402	S-adenosylhomocysteine deaminase activity
EFD32_RS04660	COG0402	S-adenosylhomocysteine deaminase activity
EFD32_RS04665	COG1956	GAF domain-containing protein
EFD32_RS04675	COG0110	maltose O-acetyltransferase activity
EFD32_RS04690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFD32_RS04695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EFD32_RS04700	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EFD32_RS04705	COG1609	Transcriptional regulator
EFD32_RS04710	COG0572	uridine kinase
EFD32_RS04730	COG2814	Major facilitator Superfamily
EFD32_RS04735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFD32_RS04765	COG0456	acetyltransferase
EFD32_RS04845	COG1132	(ABC) transporter
EFD32_RS04860	COG1113	amino acid transport
EFD32_RS04880	COG0247	lactate metabolic process
EFD32_RS04885	COG1139	Iron-sulfur cluster binding protein
EFD32_RS04900	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EFD32_RS04905	COG1074	ATP-dependent DNA helicase activity
EFD32_RS04910	COG1733	regulation of RNA biosynthetic process
EFD32_RS04915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFD32_RS04920	COG0072	phenylalanine-tRNA ligase activity
EFD32_RS04920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFD32_RS04925	COG0765	amino acid transport
EFD32_RS04930	COG0765	amino acid transport
EFD32_RS04935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EFD32_RS04945	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EFD32_RS04950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EFD32_RS04955	COG0622	Phosphoesterase
EFD32_RS04960	COG1349	DNA-binding transcription factor activity
EFD32_RS04975	COG3037	sugar-specific permease SgaT UlaA
EFD32_RS04985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EFD32_RS04990	COG3623	hexulose-6-phosphate isomerase
EFD32_RS05000	COG0517	IMP dehydrogenase activity
EFD32_RS05005	COG2171	N-acyltransferase activity
EFD32_RS05010	COG1473	amidohydrolase
EFD32_RS05015	COG0668	transmembrane transport
EFD32_RS05025	COG0656	L-ascorbic acid biosynthetic process
EFD32_RS05030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EFD32_RS05050	COG1078	dGTPase activity
EFD32_RS05055	COG0095	Lipoate-protein ligase
EFD32_RS05070	COG0504	CTP synthase activity
EFD32_RS05075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EFD32_RS05080	COG3331	DNA recombination
EFD32_RS05085	COG4474	Belongs to the UPF0398 family
EFD32_RS05090	COG3599	regulation of cell shape
EFD32_RS05095	COG0116	Belongs to the methyltransferase superfamily
EFD32_RS05100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EFD32_RS05105	COG3935	DnaD domain protein
EFD32_RS05110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFD32_RS05115	COG2188	Transcriptional regulator
EFD32_RS05125	COG1446	asparaginase
EFD32_RS05130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS05135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS05160	COG1666	GTP binding
EFD32_RS05165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFD32_RS05170	COG0191	fructose-bisphosphate aldolase activity
EFD32_RS05180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFD32_RS05185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EFD32_RS05190	COG0254	rRNA binding
EFD32_RS05205	COG1940	carbohydrate kinase activity
EFD32_RS05210	COG3237	CsbD-like
EFD32_RS05215	COG0778	Nitroreductase
EFD32_RS05220	COG1854	S-ribosylhomocysteine lyase activity
EFD32_RS05225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFD32_RS05230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFD32_RS05240	COG0737	Belongs to the 5'-nucleotidase family
EFD32_RS05245	COG4470	Protein conserved in bacteria
EFD32_RS05250	COG0647	UMP catabolic process
EFD32_RS05265	COG1307	EDD domain protein, DegV family
EFD32_RS05270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EFD32_RS05275	COG0745	RESPONSE REGULATOR receiver
EFD32_RS05280	COG5002	protein histidine kinase activity
EFD32_RS05295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EFD32_RS05300	COG0701	Predicted permease
EFD32_RS05305	COG3689	TIGRFAM TIGR03943 family protein
EFD32_RS05320	COG4472	Bacterial protein of unknown function (DUF965)
EFD32_RS05325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFD32_RS05330	COG3906	Belongs to the UPF0473 family
EFD32_RS05345	COG3493	citrate carrier protein
EFD32_RS05350	COG3290	protein histidine kinase activity
EFD32_RS05355	COG4565	transcriptional regulatory protein
EFD32_RS05360	COG0446	pyridine nucleotide-disulphide oxidoreductase
EFD32_RS05365	COG1316	TRANSCRIPTIONal
EFD32_RS05370	COG0028	Belongs to the TPP enzyme family
EFD32_RS05375	COG3527	Alpha-acetolactate decarboxylase
EFD32_RS05395	COG1175	transmembrane transport
EFD32_RS05405	COG3842	ATPase activity
EFD32_RS05415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EFD32_RS05420	COG0402	S-adenosylhomocysteine deaminase activity
EFD32_RS05440	COG3976	FMN-binding domain protein
EFD32_RS05440	COG0431	NADPH-dependent FMN reductase
EFD32_RS05440	COG1053	succinate dehydrogenase
EFD32_RS05460	COG1408	metallophosphoesterase
EFD32_RS05465	COG4209	transmembrane transport
EFD32_RS05470	COG0395	ABC-type sugar transport system, permease component
EFD32_RS05485	COG3458	cephalosporin-C deacetylase activity
EFD32_RS05500	COG3459	Glycosyltransferase 36 associated
EFD32_RS05505	COG1609	Transcriptional regulator
EFD32_RS05515	COG2188	Transcriptional regulator
EFD32_RS05520	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS05525	COG0673	inositol 2-dehydrogenase activity
EFD32_RS05530	COG2707	UPF0756 membrane protein
EFD32_RS05545	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EFD32_RS05575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFD32_RS05585	COG2801	Transposase and inactivated derivatives
EFD32_RS05605	COG0561	phosphatase activity
EFD32_RS05610	COG0745	RESPONSE REGULATOR receiver
EFD32_RS05615	COG5002	protein histidine kinase activity
EFD32_RS05615	COG3850	Histidine kinase
EFD32_RS05630	COG1368	sulfuric ester hydrolase activity
EFD32_RS05635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EFD32_RS05640	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFD32_RS05645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EFD32_RS05650	COG1388	LysM domain
EFD32_RS05650	COG4932	domain protein
EFD32_RS05655	COG0779	Required for maturation of 30S ribosomal subunits
EFD32_RS05660	COG0195	Participates in both transcription termination and antitermination
EFD32_RS05665	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EFD32_RS05675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFD32_RS05680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFD32_RS05770	COG4824	toxin secretion phage lysis holin
EFD32_RS05780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFD32_RS05785	COG0196	riboflavin kinase activity
EFD32_RS05795	COG1695	Transcriptional regulator
EFD32_RS05815	COG0772	Belongs to the SEDS family
EFD32_RS05820	COG0583	DNA-binding transcription factor activity
EFD32_RS05825	COG0583	DNA-binding transcription factor activity
EFD32_RS05830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EFD32_RS05835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EFD32_RS05840	COG1420	regulation of RNA biosynthetic process
EFD32_RS05845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFD32_RS05850	COG0443	Heat shock 70 kDa protein
EFD32_RS05860	COG0484	heat shock protein binding
EFD32_RS05865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EFD32_RS05870	COG2183	response to ionizing radiation
EFD32_RS05875	COG3091	SprT-like family
EFD32_RS05885	COG0436	Aminotransferase
EFD32_RS05930	COG2268	Band 7 protein
EFD32_RS05955	COG1309	transcriptional regulator
EFD32_RS05965	COG2188	Transcriptional regulator
EFD32_RS05970	COG4842	Belongs to the WXG100 family
EFD32_RS05995	COG1674	ftsk spoiiie
EFD32_RS06070	COG0492	ferredoxin-NADP+ reductase activity
EFD32_RS06085	COG0577	efflux transmembrane transporter activity
EFD32_RS06085	COG1136	(ABC) transporter
EFD32_RS06085	COG0577	efflux transmembrane transporter activity
EFD32_RS06085	COG1136	(ABC) transporter
EFD32_RS06095	COG3833	ABC-type maltose transport systems, permease component
EFD32_RS06100	COG1175	transmembrane transport
EFD32_RS06105	COG2182	Extracellular solute-binding protein
EFD32_RS06115	COG0366	Alpha amylase catalytic
EFD32_RS06120	COG0366	Alpha amylase catalytic
EFD32_RS06125	COG0366	Alpha amylase catalytic
EFD32_RS06135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EFD32_RS06165	COG0371	Dehydrogenase
EFD32_RS06170	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EFD32_RS06175	COG2376	Dihydroxyacetone kinase
EFD32_RS06180	COG1461	Dihydroxyacetone kinase
EFD32_RS06190	COG3425	synthase
EFD32_RS06205	COG0628	permease
EFD32_RS06215	COG1278	Cold shock
EFD32_RS06230	COG2814	Major facilitator Superfamily
EFD32_RS06235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EFD32_RS06240	COG4109	DRTGG domain
EFD32_RS06245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EFD32_RS06250	COG2824	Alkylphosphonate utilization operon protein PhnA
EFD32_RS06265	COG0513	Belongs to the DEAD box helicase family
EFD32_RS06275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFD32_RS06280	COG2384	SAM-dependent methyltransferase
EFD32_RS06285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFD32_RS06290	COG2195	Cleaves the N-terminal amino acid of tripeptides
EFD32_RS06305	COG0746	molybdenum cofactor guanylyltransferase activity
EFD32_RS06310	COG2116	formate transmembrane transporter activity
EFD32_RS06325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EFD32_RS06330	COG3383	formate dehydrogenase (NAD+) activity
EFD32_RS06335	COG0303	'Molybdopterin
EFD32_RS06340	COG0315	cyclic pyranopterin monophosphate synthase activity
EFD32_RS06355	COG0521	Mo-molybdopterin cofactor biosynthetic process
EFD32_RS06365	COG0725	ABC transporter, periplasmic molybdate-binding protein
EFD32_RS06370	COG4149	molybdate abc transporter
EFD32_RS06375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EFD32_RS06380	COG2217	Heavy metal translocating P-type atpase
EFD32_RS06395	COG1286	toxin biosynthetic process
EFD32_RS06400	COG1193	negative regulation of DNA recombination
EFD32_RS06405	COG3118	belongs to the thioredoxin family
EFD32_RS06410	COG0322	excinuclease ABC activity
EFD32_RS06420	COG4152	abc transporter atp-binding protein
EFD32_RS06425	COG1668	transmembrane transport
EFD32_RS06430	COG1609	Transcriptional regulator
EFD32_RS06435	COG1486	melibiose metabolic process
EFD32_RS06445	COG0488	(ABC) transporter
EFD32_RS06450	COG2081	HI0933 family
EFD32_RS06455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EFD32_RS06460	COG0166	Belongs to the GPI family
EFD32_RS06480	COG1269	ATP hydrolysis coupled proton transport
EFD32_RS06485	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFD32_RS06490	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
EFD32_RS06495	COG1527	subunit (C
EFD32_RS06500	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EFD32_RS06505	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EFD32_RS06510	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
EFD32_RS06515	COG1394	ATPase activity, coupled to movement of substances
EFD32_RS06525	COG1595	DNA-templated transcription, initiation
EFD32_RS06540	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EFD32_RS06545	COG0019	diaminopimelate decarboxylase activity
EFD32_RS06570	COG2151	metal-sulfur cluster biosynthetic enzyme
EFD32_RS06575	COG4948	Mandelate Racemase Muconate Lactonizing
EFD32_RS06585	COG4166	transmembrane transport
EFD32_RS06590	COG3711	transcriptional antiterminator
EFD32_RS06600	COG3711	transcriptional antiterminator
EFD32_RS06600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS06610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS06610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS06610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EFD32_RS06615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS06625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EFD32_RS06635	COG0741	lytic transglycosylase activity
EFD32_RS06640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EFD32_RS06645	COG0358	DNA primase activity
EFD32_RS06650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFD32_RS06660	COG2996	Protein conserved in bacteria
EFD32_RS06665	COG0735	belongs to the Fur family
EFD32_RS06675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFD32_RS06685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS06705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFD32_RS06720	COG4974	Belongs to the 'phage' integrase family
EFD32_RS06725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFD32_RS06730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFD32_RS06735	COG1187	pseudouridine synthase activity
EFD32_RS06740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFD32_RS06760	COG0514	ATP-dependent DNA helicase (RecQ)
EFD32_RS06770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EFD32_RS06775	COG0539	negative regulation of cytoplasmic translation
EFD32_RS06780	COG1160	GTP binding
EFD32_RS06795	COG0457	Tetratricopeptide repeat
EFD32_RS06800	COG5582	Belongs to the UPF0302 family
EFD32_RS06805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFD32_RS06810	COG1694	Mazg nucleotide pyrophosphohydrolase
EFD32_RS06815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EFD32_RS06820	COG0617	tRNA 3'-terminal CCA addition
EFD32_RS06835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EFD32_RS06840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EFD32_RS06850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFD32_RS06855	COG0287	Prephenate dehydrogenase
EFD32_RS06865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFD32_RS06870	COG0077	Prephenate dehydratase
EFD32_RS06880	COG1307	EDD domain protein, DegV family
EFD32_RS06905	COG0488	(ABC) transporter
EFD32_RS06910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFD32_RS06920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFD32_RS06925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EFD32_RS06930	COG4224	UPF0291 protein
EFD32_RS06940	COG2814	Major facilitator Superfamily
EFD32_RS06945	COG1388	LysM domain
EFD32_RS06945	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS06955	COG0735	belongs to the Fur family
EFD32_RS06960	COG0446	pyridine nucleotide-disulphide oxidoreductase
EFD32_RS06965	COG2816	NAD+ diphosphatase activity
EFD32_RS06975	COG2207	Transcriptional regulator
EFD32_RS06980	COG1132	(ABC) transporter
EFD32_RS06985	COG1132	(ABC) transporter
EFD32_RS07005	COG0753	catalase activity
EFD32_RS07010	COG0415	Belongs to the DNA photolyase family
EFD32_RS07020	COG1263	PTS System
EFD32_RS07020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS07020	COG2190	(PTS) system
EFD32_RS07025	COG0366	Alpha amylase catalytic
EFD32_RS07035	COG1609	Transcriptional regulator
EFD32_RS07045	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS07050	COG1263	PTS System
EFD32_RS07050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS07050	COG2190	(PTS) system
EFD32_RS07060	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EFD32_RS07070	COG1227	inorganic diphosphatase activity
EFD32_RS07075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFD32_RS07080	COG1882	Formate acetyltransferase
EFD32_RS07085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFD32_RS07090	COG0187	DNA topoisomerase II activity
EFD32_RS07095	COG1832	CoA-binding protein
EFD32_RS07100	COG4766	ethanolamine catabolic process
EFD32_RS07105	COG3192	ethanolamine utilization protein
EFD32_RS07110	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EFD32_RS07120	COG4869	propanediol catabolic process
EFD32_RS07135	COG1012	belongs to the aldehyde dehydrogenase family
EFD32_RS07135	COG1454	alcohol dehydrogenase
EFD32_RS07150	COG4302	ethanolamine ammonia-lyase activity
EFD32_RS07155	COG4303	Ethanolamine ammonia lyase large subunit
EFD32_RS07185	COG2096	Adenosyltransferase
EFD32_RS07195	COG1120	ATPase activity
EFD32_RS07200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD32_RS07205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EFD32_RS07210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EFD32_RS07220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EFD32_RS07225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EFD32_RS07230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EFD32_RS07240	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EFD32_RS07245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFD32_RS07250	COG1266	CAAX protease self-immunity
EFD32_RS07255	COG0758	DNA mediated transformation
EFD32_RS07260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFD32_RS07270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFD32_RS07275	COG0583	DNA-binding transcription factor activity
EFD32_RS07285	COG0508	dehydrogenase complex catalyzes the overall conversion of
EFD32_RS07290	COG0022	dehydrogenase e1 component
EFD32_RS07295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EFD32_RS07300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFD32_RS07305	COG3426	butyrate kinase activity
EFD32_RS07310	COG0280	phosphate acetyltransferase
EFD32_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
EFD32_RS07340	COG0346	lactoylglutathione lyase activity
EFD32_RS07350	COG0604	alcohol dehydrogenase
EFD32_RS07355	COG0577	efflux transmembrane transporter activity
EFD32_RS07360	COG1136	(ABC) transporter
EFD32_RS07370	COG1131	(ABC) transporter
EFD32_RS07385	COG0681	Belongs to the peptidase S26 family
EFD32_RS07390	COG3409	Peptidoglycan-binding domain 1 protein
EFD32_RS07390	COG0793	Belongs to the peptidase S41A family
EFD32_RS07395	COG4479	Belongs to the UPF0346 family
EFD32_RS07400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFD32_RS07405	COG4698	Protein conserved in bacteria
EFD32_RS07410	COG2755	lipolytic protein G-D-S-L family
EFD32_RS07415	COG1307	EDD domain protein, DegV family
EFD32_RS07420	COG1272	protein, Hemolysin III
EFD32_RS07430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFD32_RS07435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EFD32_RS07435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EFD32_RS07440	COG5416	Lipopolysaccharide assembly protein A domain
EFD32_RS07445	COG0300	oxidoreductase activity
EFD32_RS07450	COG1234	tRNA 3'-trailer cleavage
EFD32_RS07460	COG1837	Belongs to the UPF0109 family
EFD32_RS07465	COG0228	four-way junction DNA binding
EFD32_RS07470	COG0456	acetyltransferase
EFD32_RS07470	COG1214	PFAM Peptidase M22, glycoprotease
EFD32_RS07475	COG0431	NADPH-dependent FMN reductase
EFD32_RS07480	COG0789	Transcriptional regulator
EFD32_RS07485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFD32_RS07490	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFD32_RS07495	COG1683	Conserved Protein
EFD32_RS07500	COG0745	RESPONSE REGULATOR receiver
EFD32_RS07505	COG5002	protein histidine kinase activity
EFD32_RS07515	COG0436	Aminotransferase
EFD32_RS07520	COG0383	alpha-mannosidase activity
EFD32_RS07535	COG0583	DNA-binding transcription factor activity
EFD32_RS07550	COG0284	orotidine-5'-phosphate decarboxylase activity
EFD32_RS07560	COG0543	2 iron, 2 sulfur cluster binding
EFD32_RS07565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EFD32_RS07570	COG0505	Belongs to the CarA family
EFD32_RS07575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EFD32_RS07580	COG0540	Belongs to the ATCase OTCase family
EFD32_RS07585	COG2233	PERMEase
EFD32_RS07595	COG0564	pseudouridine synthase activity
EFD32_RS07600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFD32_RS07610	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EFD32_RS07615	COG1278	Cold shock
EFD32_RS07625	COG0328	RNA-DNA hybrid ribonuclease activity
EFD32_RS07630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFD32_RS07635	COG0710	3-dehydroquinate dehydratase activity
EFD32_RS07640	COG1132	(ABC) transporter
EFD32_RS07645	COG1132	(ABC) transporter
EFD32_RS07650	COG3763	UPF0154 protein
EFD32_RS07660	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EFD32_RS07675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFD32_RS07690	COG1131	(ABC) transporter
EFD32_RS07700	COG1609	Transcriptional regulator
EFD32_RS07705	COG0006	proline dipeptidase activity
EFD32_RS07710	COG4980	gas vesicle protein
EFD32_RS07720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EFD32_RS07725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EFD32_RS07730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFD32_RS07735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFD32_RS07740	COG0322	excinuclease ABC activity
EFD32_RS07745	COG1950	PFAM Membrane protein of
EFD32_RS07755	COG3595	metallopeptidase activity
EFD32_RS07760	COG0704	Plays a role in the regulation of phosphate uptake
EFD32_RS07765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EFD32_RS07770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EFD32_RS07775	COG0581	inorganic phosphate transmembrane transporter activity
EFD32_RS07780	COG0573	inorganic phosphate transmembrane transporter activity
EFD32_RS07790	COG2177	Part of the ABC transporter FtsEX involved in
EFD32_RS07795	COG2884	Cell division ATP-binding protein ftsE
EFD32_RS07800	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFD32_RS07805	COG0653	protein targeting
EFD32_RS07820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFD32_RS07830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS07840	COG1739	Uncharacterized protein family UPF0029
EFD32_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
EFD32_RS07875	COG0151	Belongs to the GarS family
EFD32_RS07880	COG0138	bifunctional purine biosynthesis protein purh
EFD32_RS07885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFD32_RS07890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EFD32_RS07900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFD32_RS07905	COG0047	phosphoribosylformylglycinamidine synthase activity
EFD32_RS07910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFD32_RS07915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EFD32_RS07920	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFD32_RS07925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFD32_RS07935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EFD32_RS07940	COG4166	transmembrane transport
EFD32_RS07950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EFD32_RS07955	COG4876	unkown
EFD32_RS07970	COG0628	permease
EFD32_RS07980	COG0366	Alpha amylase catalytic
EFD32_RS07980	COG1470	cell adhesion involved in biofilm formation
EFD32_RS07990	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS07995	COG3715	PTS system
EFD32_RS08000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS08000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EFD32_RS08010	COG1105	Belongs to the carbohydrate kinase PfkB family
EFD32_RS08015	COG3684	Belongs to the aldolase LacD family
EFD32_RS08020	COG2222	sugar isomerase
EFD32_RS08025	COG2188	Transcriptional regulator
EFD32_RS08030	COG1442	glycosyl transferase family 8
EFD32_RS08035	COG1442	glycosyl transferase family 8
EFD32_RS08040	COG1368	sulfuric ester hydrolase activity
EFD32_RS08050	COG0583	DNA-binding transcription factor activity
EFD32_RS08065	COG3227	Zinc metalloprotease (Elastase)
EFD32_RS08085	COG3942	CHAP domain
EFD32_RS08085	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS08160	COG0335	large ribosomal subunit rRNA binding
EFD32_RS08165	COG0336	Belongs to the RNA methyltransferase TrmD family
EFD32_RS08170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFD32_RS08175	COG1914	H( )-stimulated, divalent metal cation uptake system
EFD32_RS08185	COG0398	Pfam SNARE associated Golgi protein
EFD32_RS08190	COG0584	glycerophosphoryl diester phosphodiesterase
EFD32_RS08205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EFD32_RS08215	COG4129	membrane
EFD32_RS08225	COG1940	carbohydrate kinase activity
EFD32_RS08230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EFD32_RS08240	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EFD32_RS08245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFD32_RS08250	COG2706	6-phosphogluconolactonase activity
EFD32_RS08260	COG3069	C4-dicarboxylate transmembrane transporter activity
EFD32_RS08290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EFD32_RS08300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EFD32_RS08345	COG2364	Membrane
EFD32_RS08350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EFD32_RS08360	COG2814	Major facilitator Superfamily
EFD32_RS08365	COG1368	sulfuric ester hydrolase activity
EFD32_RS08400	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS08405	COG3715	PTS system
EFD32_RS08420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EFD32_RS08420	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EFD32_RS08430	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EFD32_RS08445	COG0149	triose-phosphate isomerase activity
EFD32_RS08450	COG0126	phosphoglycerate kinase activity
EFD32_RS08460	COG2390	Transcriptional regulator
EFD32_RS08465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFD32_RS08470	COG4475	Protein of unknown function (DUF436)
EFD32_RS08475	COG4720	Psort location CytoplasmicMembrane, score
EFD32_RS08480	COG0351	phosphomethylpyrimidine kinase
EFD32_RS08485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EFD32_RS08490	COG0124	histidyl-tRNA synthetase
EFD32_RS08500	COG1490	D-aminoacyl-tRNA deacylase activity
EFD32_RS08505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFD32_RS08510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EFD32_RS08515	COG2264	protein methyltransferase activity
EFD32_RS08525	COG2094	Belongs to the DNA glycosylase MPG family
EFD32_RS08530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EFD32_RS08545	COG0589	response to stress
EFD32_RS08550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFD32_RS08555	COG0827	DNA restriction-modification system
EFD32_RS08580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EFD32_RS08600	COG1278	Cold shock
EFD32_RS08605	COG3942	CHAP domain
EFD32_RS08605	COG1388	LysM domain
EFD32_RS08725	COG1783	phage Terminase large subunit
EFD32_RS08790	COG3935	DnaD domain protein
EFD32_RS08795	COG3723	Recombinational DNA repair protein, rece pathway
EFD32_RS08800	COG5377	YqaJ viral recombinase family
EFD32_RS08835	COG3646	Phage regulatory protein
EFD32_RS08850	COG1396	sequence-specific DNA binding
EFD32_RS08870	COG0582	viral genome integration into host DNA
EFD32_RS08880	COG4537	Required for transformation and DNA binding
EFD32_RS08890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFD32_RS08895	COG0531	amino acid
EFD32_RS08900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EFD32_RS08905	COG0577	efflux transmembrane transporter activity
EFD32_RS08910	COG1136	(ABC) transporter
EFD32_RS08920	COG1674	ftsk spoiiie
EFD32_RS08925	COG1252	NADH dehydrogenase
EFD32_RS08940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EFD32_RS08945	COG4988	ABC transporter
EFD32_RS08950	COG1294	oxidase, subunit
EFD32_RS08955	COG1271	oxidase subunit
EFD32_RS08960	COG3708	Transcriptional regulator
EFD32_RS08960	COG2207	Transcriptional regulator
EFD32_RS08980	COG1881	PFAM PEBP family protein
EFD32_RS08985	COG2814	Major facilitator Superfamily
EFD32_RS08995	COG0482	sulfurtransferase activity
EFD32_RS09005	COG1104	cysteine desulfurase activity
EFD32_RS09010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFD32_RS09015	COG1121	(ABC) transporter
EFD32_RS09020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EFD32_RS09030	COG0488	(ABC) transporter
EFD32_RS09040	COG1473	amidohydrolase
EFD32_RS09050	COG2011	ABC-type metal ion transport system permease component
EFD32_RS09055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFD32_RS09100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EFD32_RS09110	COG1122	ATPase activity
EFD32_RS09115	COG4720	Psort location CytoplasmicMembrane, score
EFD32_RS09120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFD32_RS09130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFD32_RS09145	COG0789	Transcriptional regulator
EFD32_RS09150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFD32_RS09155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFD32_RS09160	COG0584	glycerophosphoryl diester phosphodiesterase
EFD32_RS09175	COG0438	transferase activity, transferring glycosyl groups
EFD32_RS09175	COG4641	Protein conserved in bacteria
EFD32_RS09180	COG3475	LICD family
EFD32_RS09195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EFD32_RS09215	COG3475	LICD family
EFD32_RS09220	COG1216	Glycosyl transferase, family 2
EFD32_RS09225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EFD32_RS09240	COG0438	transferase activity, transferring glycosyl groups
EFD32_RS09240	COG1216	Glycosyl transferase, family 2
EFD32_RS09245	COG0438	transferase activity, transferring glycosyl groups
EFD32_RS09245	COG1216	Glycosyl transferase, family 2
EFD32_RS09250	COG1134	teichoic acid transport
EFD32_RS09255	COG1682	transport, permease protein
EFD32_RS09270	COG1215	transferase activity, transferring glycosyl groups
EFD32_RS09275	COG1091	dTDP-4-dehydrorhamnose reductase activity
EFD32_RS09280	COG1088	dTDP-glucose 4,6-dehydratase activity
EFD32_RS09290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EFD32_RS09310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFD32_RS09315	COG1295	ribonuclease BN
EFD32_RS09320	COG0024	Methionine aminopeptidase
EFD32_RS09325	COG0716	FMN binding
EFD32_RS09330	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EFD32_RS09335	COG1309	transcriptional regulator
EFD32_RS09340	COG2309	aminopeptidase activity
EFD32_RS09345	COG0590	tRNA wobble adenosine to inosine editing
EFD32_RS09355	COG0384	phenazine biosynthesis protein PhzF
EFD32_RS09365	COG2738	Putative neutral zinc metallopeptidase
EFD32_RS09380	COG1263	PTS System
EFD32_RS09380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS09385	COG0346	lactoylglutathione lyase activity
EFD32_RS09405	COG4753	response regulator
EFD32_RS09405	COG2207	Transcriptional regulator
EFD32_RS09410	COG2972	Histidine kinase
EFD32_RS09420	COG1653	transport
EFD32_RS09425	COG0395	ABC-type sugar transport system, permease component
EFD32_RS09430	COG1175	transmembrane transport
EFD32_RS09435	COG1266	CAAX protease self-immunity
EFD32_RS09455	COG1132	(ABC) transporter
EFD32_RS09480	COG0395	ABC-type sugar transport system, permease component
EFD32_RS09485	COG1175	transmembrane transport
EFD32_RS09495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EFD32_RS09510	COG1609	Transcriptional regulator
EFD32_RS09525	COG1401	restriction endodeoxyribonuclease activity
EFD32_RS09530	COG0582	viral genome integration into host DNA
EFD32_RS09615	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EFD32_RS09630	COG0392	lysyltransferase activity
EFD32_RS09630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFD32_RS09660	COG4115	mRNA cleavage
EFD32_RS09735	COG0629	single-stranded DNA binding
EFD32_RS09800	COG1862	Preprotein translocase
EFD32_RS09855	COG1086	Polysaccharide biosynthesis protein
EFD32_RS09865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EFD32_RS09870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EFD32_RS09885	COG4464	protein tyrosine phosphatase activity
EFD32_RS09890	COG0489	protein tyrosine kinase activity
EFD32_RS09900	COG1316	TRANSCRIPTIONal
EFD32_RS09955	COG2801	Transposase and inactivated derivatives
EFD32_RS09965	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EFD32_RS09985	COG1136	(ABC) transporter
EFD32_RS09990	COG0577	efflux transmembrane transporter activity
EFD32_RS10000	COG5002	protein histidine kinase activity
EFD32_RS10030	COG0629	single-stranded DNA binding
EFD32_RS10080	COG2337	Toxic component of a toxin-antitoxin (TA) module
EFD32_RS10090	COG0791	NLP P60 protein
EFD32_RS10090	COG0741	lytic transglycosylase activity
EFD32_RS10250	COG0481	GTPase activity
EFD32_RS10265	COG0542	response to heat
EFD32_RS10275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFD32_RS10280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFD32_RS10295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFD32_RS10305	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS10325	COG0017	Asparaginyl-tRNA synthetase
EFD32_RS10330	COG0436	Aminotransferase
EFD32_RS10340	COG1199	ATP-dependent helicase activity
EFD32_RS10340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EFD32_RS10355	COG0531	amino acid
EFD32_RS10365	COG0442	prolyl-tRNA aminoacylation
EFD32_RS10370	COG0750	zinc metalloprotease
EFD32_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
EFD32_RS10415	COG0515	serine threonine protein kinase
EFD32_RS10415	COG2815	serine threonine protein kinase
EFD32_RS10425	COG0719	Fe-S assembly protein
EFD32_RS10435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFD32_RS10440	COG0719	Fe-S assembly protein
EFD32_RS10450	COG0233	cytoplasmic translational termination
EFD32_RS10455	COG0528	UMP kinase activity
EFD32_RS10460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFD32_RS10465	COG0052	Belongs to the universal ribosomal protein uS2 family
EFD32_RS10475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFD32_RS10480	COG1254	Belongs to the acylphosphatase family
EFD32_RS10485	COG0706	membrane insertase activity
EFD32_RS10495	COG0751	glycine-tRNA ligase activity
EFD32_RS10500	COG0752	glycyl-tRNA synthetase alpha subunit
EFD32_RS10505	COG1381	Involved in DNA repair and RecF pathway recombination
EFD32_RS10510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFD32_RS10515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EFD32_RS10520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFD32_RS10530	COG1702	phosphate starvation-inducible protein PhoH
EFD32_RS10535	COG1610	YqeY-like protein
EFD32_RS10540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EFD32_RS10545	COG0735	belongs to the Fur family
EFD32_RS10550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EFD32_RS10555	COG0083	homoserine kinase activity
EFD32_RS10565	COG0460	homoserine dehydrogenase
EFD32_RS10570	COG0640	Transcriptional regulator
EFD32_RS10575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFD32_RS10580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFD32_RS10585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EFD32_RS10600	COG0516	GMP reductase activity
EFD32_RS10610	COG0402	S-adenosylhomocysteine deaminase activity
EFD32_RS10625	COG1737	Transcriptional regulator
EFD32_RS10630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS10630	COG1263	PTS System
EFD32_RS10635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EFD32_RS10645	COG2190	(PTS) system
EFD32_RS10645	COG1263	PTS System
EFD32_RS10645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS10650	COG1968	undecaprenyl-diphosphatase activity
EFD32_RS10655	COG3394	polysaccharide catabolic process
EFD32_RS10665	COG0306	phosphate transporter
EFD32_RS10670	COG0268	Binds directly to 16S ribosomal RNA
EFD32_RS10675	COG1607	acyl-coa hydrolase
EFD32_RS10680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFD32_RS10685	COG1466	dna polymerase III delta subunit
EFD32_RS10690	COG2333	competence protein COMEC
EFD32_RS10690	COG0658	competence protein
EFD32_RS10700	COG2131	deaminase
EFD32_RS10705	COG1555	photosystem II stabilization
EFD32_RS10710	COG3480	Lon protease (S16) C-terminal proteolytic domain
EFD32_RS10715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFD32_RS10720	COG0742	ribosomal rna small subunit methyltransferase
EFD32_RS10725	COG4471	UPF0298 protein
EFD32_RS10740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EFD32_RS10745	COG0772	Belongs to the SEDS family
EFD32_RS10750	COG4838	Belongs to the UPF0358 family
EFD32_RS10755	COG0514	ATP-dependent DNA helicase (RecQ)
EFD32_RS10760	COG1217	gtp-binding protein TYPA
EFD32_RS10765	COG0483	inositol monophosphate 1-phosphatase activity
EFD32_RS10770	COG4476	Belongs to the UPF0223 family
EFD32_RS10775	COG0038	chloride channel
EFD32_RS10780	COG1215	transferase activity, transferring glycosyl groups
EFD32_RS10810	COG0018	arginyl-trna synthetase
EFD32_RS10815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFD32_RS10820	COG0456	acetyltransferase
EFD32_RS10830	COG1214	PFAM Peptidase M22, glycoprotease
EFD32_RS10875	COG4589	Belongs to the CDS family
EFD32_RS10880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFD32_RS10885	COG1464	Belongs to the NlpA lipoprotein family
EFD32_RS10890	COG2011	ABC-type metal ion transport system permease component
EFD32_RS10895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFD32_RS10905	COG0509	glycine decarboxylation via glycine cleavage system
EFD32_RS10910	COG1393	Belongs to the ArsC family
EFD32_RS10915	COG0772	Belongs to the SEDS family
EFD32_RS10940	COG1396	sequence-specific DNA binding
EFD32_RS10970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFD32_RS10975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFD32_RS10980	COG0009	L-threonylcarbamoyladenylate synthase
EFD32_RS10985	COG2890	protein-(glutamine-N5) methyltransferase activity
EFD32_RS10990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFD32_RS10995	COG1435	thymidine kinase activity
EFD32_RS11000	COG1053	succinate dehydrogenase
EFD32_RS11005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EFD32_RS11015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EFD32_RS11015	COG0493	'glutamate synthase
EFD32_RS11020	COG0543	2 iron, 2 sulfur cluster binding
EFD32_RS11025	COG0716	FMN binding
EFD32_RS11030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EFD32_RS11030	COG3608	succinylglutamate desuccinylase aspartoacylase
EFD32_RS11035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFD32_RS11055	COG1104	cysteine desulfurase activity
EFD32_RS11060	COG0746	molybdenum cofactor guanylyltransferase activity
EFD32_RS11070	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EFD32_RS11070	COG3608	succinylglutamate desuccinylase aspartoacylase
EFD32_RS11085	COG0251	oxidation-reduction process
EFD32_RS11090	COG0549	Belongs to the carbamate kinase family
EFD32_RS11095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFD32_RS11100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EFD32_RS11115	COG0493	'glutamate synthase
EFD32_RS11115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EFD32_RS11120	COG0402	S-adenosylhomocysteine deaminase activity
EFD32_RS11135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EFD32_RS11140	COG3442	glutamine amidotransferase
EFD32_RS11145	COG1957	nucleoside hydrolase
EFD32_RS11155	COG1482	cell wall glycoprotein biosynthetic process
EFD32_RS11170	COG1132	(ABC) transporter
EFD32_RS11185	COG0194	GDP metabolic process
EFD32_RS11190	COG2723	6-phospho-beta-galactosidase activity
EFD32_RS11195	COG2190	(PTS) system
EFD32_RS11195	COG1263	PTS System
EFD32_RS11195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS11200	COG3711	transcriptional antiterminator
EFD32_RS11205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EFD32_RS11210	COG0628	permease
EFD32_RS11225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFD32_RS11230	COG4836	Membrane
EFD32_RS11235	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EFD32_RS11240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFD32_RS11245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFD32_RS11250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFD32_RS11255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFD32_RS11260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EFD32_RS11265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFD32_RS11270	COG0356	it plays a direct role in the translocation of protons across the membrane
EFD32_RS11280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EFD32_RS11285	COG0557	exoribonuclease II activity
EFD32_RS11300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EFD32_RS11305	COG2388	GCN5-related N-acetyl-transferase
EFD32_RS11310	COG3592	Divergent 4Fe-4S mono-cluster
EFD32_RS11320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EFD32_RS11325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFD32_RS11330	COG2246	polysaccharide biosynthetic process
EFD32_RS11335	COG1705	Flagellar rod assembly protein muramidase FlgJ
EFD32_RS11335	COG3942	CHAP domain
EFD32_RS11350	COG0459	protein refolding
EFD32_RS11355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFD32_RS11370	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFD32_RS11375	COG0488	(ABC) transporter
EFD32_RS11385	COG3448	diguanylate cyclase activity
EFD32_RS11385	COG4175	Glycine betaine
EFD32_RS11400	COG1597	lipid kinase activity
EFD32_RS11405	COG3835	regulator
EFD32_RS11410	COG1929	Belongs to the glycerate kinase type-1 family
EFD32_RS11415	COG2610	gluconate transmembrane transporter activity
EFD32_RS11425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EFD32_RS11430	COG1177	transmembrane transport
EFD32_RS11435	COG1176	ABC-type spermidine putrescine transport system, permease component I
EFD32_RS11440	COG3842	ATPase activity
EFD32_RS11450	COG0604	alcohol dehydrogenase
EFD32_RS11460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFD32_RS11465	COG4684	Psort location CytoplasmicMembrane, score
EFD32_RS11470	COG2348	transferase activity, transferring amino-acyl groups
EFD32_RS11485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EFD32_RS11495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EFD32_RS11505	COG3142	Participates in the control of copper homeostasis
EFD32_RS11510	COG2239	Acts as a magnesium transporter
EFD32_RS11515	COG0564	pseudouridine synthase activity
EFD32_RS11520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFD32_RS11525	COG2357	RelA SpoT domain protein
EFD32_RS11530	COG4116	CYTH
EFD32_RS11545	COG1164	Oligoendopeptidase f
EFD32_RS11555	COG4862	establishment of competence for transformation
EFD32_RS11560	COG1393	Belongs to the ArsC family
EFD32_RS11565	COG0180	Tryptophanyl-tRNA synthetase
EFD32_RS11570	COG1132	(ABC) transporter
EFD32_RS11600	COG4824	toxin secretion phage lysis holin
EFD32_RS11675	COG0740	serine-type endopeptidase activity
EFD32_RS11715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EFD32_RS11755	COG0582	viral genome integration into host DNA
EFD32_RS11855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EFD32_RS11860	COG1132	(ABC) transporter
EFD32_RS11875	COG2801	Transposase and inactivated derivatives
EFD32_RS11915	COG0419	ATPase involved in DNA repair
EFD32_RS11920	COG0420	3'-5' exonuclease activity
EFD32_RS11925	COG0204	Acyl-transferase
EFD32_RS11930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EFD32_RS11935	COG2827	Endonuclease containing a URI domain
EFD32_RS11940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFD32_RS11950	COG0494	nUDIX hydrolase
EFD32_RS11960	COG3853	Toxic anion resistance protein (TelA)
EFD32_RS11990	COG1194	a g-specific adenine glycosylase
EFD32_RS11995	COG2137	regulation of response to DNA damage stimulus
EFD32_RS12000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFD32_RS12010	COG2261	transglycosylase associated protein
EFD32_RS12015	COG3250	beta-galactosidase activity
EFD32_RS12020	COG0531	amino acid
EFD32_RS12025	COG2207	Transcriptional regulator
EFD32_RS12025	COG1917	Cupin 2, conserved barrel domain protein
EFD32_RS12035	COG0222	ribosome binding
EFD32_RS12040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFD32_RS12045	COG0081	regulation of translation
EFD32_RS12050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFD32_RS12055	COG0488	(ABC) transporter
EFD32_RS12060	COG1760	l-serine dehydratase
EFD32_RS12065	COG1760	l-serine dehydratase
EFD32_RS12075	COG1363	Peptidase, m42
EFD32_RS12080	COG4166	transmembrane transport
EFD32_RS12095	COG0250	Participates in transcription elongation, termination and antitermination
EFD32_RS12100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EFD32_RS12105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EFD32_RS12120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EFD32_RS12130	COG0708	Exodeoxyribonuclease III
EFD32_RS12160	COG0095	Lipoate-protein ligase
EFD32_RS12165	COG1234	tRNA 3'-trailer cleavage
EFD32_RS12175	COG1363	Peptidase, m42
EFD32_RS12180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFD32_RS12185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFD32_RS12190	COG1696	Membrane protein involved in D-alanine export
EFD32_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EFD32_RS12205	COG0577	efflux transmembrane transporter activity
EFD32_RS12210	COG1136	(ABC) transporter
EFD32_RS12215	COG1328	CTP reductase activity
EFD32_RS12220	COG0602	queuosine metabolic process
EFD32_RS12230	COG0390	transport system, permease component
EFD32_RS12235	COG4619	ABC transporter
EFD32_RS12245	COG4467	Involved in initiation control of chromosome replication
EFD32_RS12250	COG1774	PSP1 C-terminal conserved region
EFD32_RS12255	COG0470	DNA polymerase III
EFD32_RS12260	COG3870	Protein conserved in bacteria
EFD32_RS12265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFD32_RS12275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFD32_RS12280	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EFD32_RS12290	COG1122	ATPase activity
EFD32_RS12305	COG0477	Major facilitator Superfamily
EFD32_RS12310	COG2814	Major facilitator Superfamily
EFD32_RS12315	COG1733	regulation of RNA biosynthetic process
EFD32_RS12320	COG0351	phosphomethylpyrimidine kinase
EFD32_RS12325	COG0352	thiamine-phosphate diphosphorylase activity
EFD32_RS12330	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EFD32_RS12340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFD32_RS12345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFD32_RS12350	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EFD32_RS12355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EFD32_RS12370	COG3189	MarR family transcriptional regulator
EFD32_RS12375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFD32_RS12380	COG1940	carbohydrate kinase activity
EFD32_RS12395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFD32_RS12400	COG1073	alpha beta
EFD32_RS12435	COG3942	CHAP domain
EFD32_RS12435	COG1388	LysM domain
EFD32_RS12685	COG1396	sequence-specific DNA binding
EFD32_RS12695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EFD32_RS12705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EFD32_RS12710	COG0768	penicillin binding
EFD32_RS12715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFD32_RS12720	COG1942	4-Oxalocrotonate Tautomerase
EFD32_RS12725	COG1876	peptidase activity
EFD32_RS12765	COG0217	transcriptional regulatory protein
EFD32_RS12770	COG1323	Belongs to the UPF0348 family
EFD32_RS12775	COG2226	methyltransferase
EFD32_RS12780	COG0799	negative regulation of ribosome biogenesis
EFD32_RS12785	COG1713	HD superfamily hydrolase involved in NAD metabolism
EFD32_RS12790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFD32_RS12795	COG1534	Rna-binding protein
EFD32_RS12800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFD32_RS12810	COG0825	malonyl-CoA metabolic process
EFD32_RS12815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFD32_RS12820	COG0439	Biotin carboxylase
EFD32_RS12825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EFD32_RS12835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EFD32_RS12845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EFD32_RS12860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFD32_RS12865	COG1846	Transcriptional regulator
EFD32_RS12870	COG4703	Protein of unknown function (DUF1797)
EFD32_RS12875	COG2084	Dehydrogenase
EFD32_RS12880	COG0438	transferase activity, transferring glycosyl groups
EFD32_RS12925	COG1098	S1 RNA binding domain
EFD32_RS12930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EFD32_RS12945	COG0492	ferredoxin-NADP+ reductase activity
EFD32_RS12960	COG0737	Belongs to the 5'-nucleotidase family
EFD32_RS12980	COG1175	transmembrane transport
EFD32_RS12985	COG3842	ATPase activity
EFD32_RS12990	COG0463	Glycosyl transferase, family 2
EFD32_RS12995	COG4841	protein insertion into membrane
EFD32_RS13000	COG0569	domain protein
EFD32_RS13005	COG2197	response regulator
EFD32_RS13010	COG4585	Histidine kinase
EFD32_RS13020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EFD32_RS13025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EFD32_RS13035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EFD32_RS13040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EFD32_RS13055	COG2832	Protein of unknown function (DUF454)
EFD32_RS13060	COG5503	Protein of unknown function (DUF1447)
EFD32_RS13070	COG1278	Cold shock
EFD32_RS13075	COG2003	Belongs to the UPF0758 family
EFD32_RS13080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EFD32_RS13085	COG0285	dihydrofolate synthase activity
EFD32_RS13100	COG0525	valine-tRNA ligase activity
EFD32_RS13105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFD32_RS13110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFD32_RS13115	COG0301	tRNA thio-modification
EFD32_RS13120	COG2252	PERMEase
EFD32_RS13125	COG4221	oxidoreductase activity
EFD32_RS13130	COG0110	maltose O-acetyltransferase activity
EFD32_RS13135	COG0583	DNA-binding transcription factor activity
EFD32_RS13140	COG4975	Glucose uptake
EFD32_RS13145	COG1869	D-ribose catabolic process
EFD32_RS13155	COG1609	Transcriptional regulator
EFD32_RS13160	COG0657	acetylesterase activity
EFD32_RS13175	COG3711	transcriptional antiterminator
EFD32_RS13200	COG1834	amidinotransferase
EFD32_RS13205	COG1785	Belongs to the alkaline phosphatase family
EFD32_RS13210	COG1193	negative regulation of DNA recombination
EFD32_RS13225	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS13230	COG3715	PTS system
EFD32_RS13235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS13265	COG0577	efflux transmembrane transporter activity
EFD32_RS13270	COG1136	(ABC) transporter
EFD32_RS13275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFD32_RS13285	COG0446	pyridine nucleotide-disulphide oxidoreductase
EFD32_RS13295	COG1937	Protein conserved in bacteria
EFD32_RS13305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EFD32_RS13310	COG2508	Transcriptional regulator
EFD32_RS13315	COG3257	ureidoglycine aminohydrolase activity
EFD32_RS13320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EFD32_RS13325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EFD32_RS13330	COG1953	Uracil, thiamine, allantoin
EFD32_RS13340	COG1846	Transcriptional regulator
EFD32_RS13350	COG0659	secondary active sulfate transmembrane transporter activity
EFD32_RS13355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EFD32_RS13365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EFD32_RS13400	COG2508	Transcriptional regulator
EFD32_RS13410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EFD32_RS13415	COG1304	FMN binding
EFD32_RS13430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EFD32_RS13435	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EFD32_RS13470	COG1823	symporter activity
EFD32_RS13475	COG5492	domain, Protein
EFD32_RS13485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFD32_RS13490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFD32_RS13495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFD32_RS13500	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS13505	COG3715	PTS system
EFD32_RS13510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS13525	COG2188	Transcriptional regulator
EFD32_RS13535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EFD32_RS13540	COG1363	Peptidase, m42
EFD32_RS13555	COG4166	transmembrane transport
EFD32_RS13560	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS13565	COG3715	PTS system
EFD32_RS13570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFD32_RS13575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS13590	COG3394	polysaccharide catabolic process
EFD32_RS13600	COG0519	Catalyzes the synthesis of GMP from XMP
EFD32_RS13630	COG3764	Sortase (surface protein transpeptidase)
EFD32_RS13640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFD32_RS13670	COG1185	polyribonucleotide nucleotidyltransferase activity
EFD32_RS13675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFD32_RS13680	COG0242	peptide deformylase activity
EFD32_RS13700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFD32_RS13710	COG1268	BioY protein
EFD32_RS13715	COG0681	Belongs to the peptidase S26 family
EFD32_RS13735	COG4493	Belongs to the UPF0637 family
EFD32_RS13745	COG2195	Cleaves the N-terminal amino acid of tripeptides
EFD32_RS13750	COG4166	transmembrane transport
EFD32_RS13755	COG4607	ABC-type enterochelin transport system periplasmic component
EFD32_RS13760	COG4604	ABC transporter, ATP-binding protein
EFD32_RS13765	COG4605	iron ion homeostasis
EFD32_RS13770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFD32_RS13790	COG1181	Belongs to the D-alanine--D-alanine ligase family
EFD32_RS13790	COG2918	glutathione biosynthetic process
EFD32_RS13800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFD32_RS13815	COG0552	protein localization to endoplasmic reticulum
EFD32_RS13820	COG0561	phosphatase activity
EFD32_RS13825	COG1196	nuclear chromosome segregation
EFD32_RS13830	COG1196	nuclear chromosome segregation
EFD32_RS13835	COG0571	ribonuclease III activity
EFD32_RS13850	COG0601	transmembrane transport
EFD32_RS13855	COG4608	Belongs to the ABC transporter superfamily
EFD32_RS13865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFD32_RS13870	COG0416	fatty acid biosynthetic process
EFD32_RS13875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFD32_RS13880	COG1461	Dihydroxyacetone kinase
EFD32_RS13890	COG3279	Response regulator of the LytR AlgR family
EFD32_RS13900	COG1668	transmembrane transport
EFD32_RS13905	COG4152	abc transporter atp-binding protein
EFD32_RS13910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EFD32_RS13920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EFD32_RS13925	COG1162	GTPase activity
EFD32_RS13930	COG0515	serine threonine protein kinase
EFD32_RS13930	COG2815	serine threonine protein kinase
EFD32_RS13940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFD32_RS13940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFD32_RS13945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFD32_RS13955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFD32_RS13960	COG1758	RNA polymerase activity
EFD32_RS13965	COG0194	GDP metabolic process
EFD32_RS13995	COG0800	Aldolase
EFD32_RS14000	COG1312	Catalyzes the dehydration of D-mannonate
EFD32_RS14010	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EFD32_RS14015	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS14025	COG0371	Dehydrogenase
EFD32_RS14035	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EFD32_RS14040	COG1737	Transcriptional regulator
EFD32_RS14055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFD32_RS14090	COG1426	Protein conserved in bacteria
EFD32_RS14095	COG0612	Peptidase, M16
EFD32_RS14100	COG0612	Peptidase, M16
EFD32_RS14105	COG1970	mechanosensitive ion channel activity
EFD32_RS14115	COG2188	Transcriptional regulator
EFD32_RS14120	COG1554	hydrolase, family 65, central catalytic
EFD32_RS14125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EFD32_RS14130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFD32_RS14140	COG0424	maF-like protein
EFD32_RS14145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFD32_RS14150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFD32_RS14155	COG4550	Control of competence regulator ComK, YlbF/YmcA
EFD32_RS14160	COG1692	metallophosphoesterase
EFD32_RS14165	COG1418	mRNA catabolic process
EFD32_RS14170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFD32_RS14175	COG1546	Belongs to the CinA family
EFD32_RS14175	COG1058	Belongs to the CinA family
EFD32_RS14180	COG2433	Pfam Transposase IS66
EFD32_RS14185	COG2910	NAD(P)H-binding
EFD32_RS14190	COG1959	2 iron, 2 sulfur cluster binding
EFD32_RS14205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EFD32_RS14265	COG1335	isochorismatase
EFD32_RS14270	COG1346	cytolysis
EFD32_RS14280	COG3279	Response regulator of the LytR AlgR family
EFD32_RS14285	COG3275	phosphorelay sensor kinase activity
EFD32_RS14295	COG2011	ABC-type metal ion transport system permease component
EFD32_RS14310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFD32_RS14315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EFD32_RS14330	COG3443	Belongs to the bacterial solute-binding protein 9 family
EFD32_RS14330	COG0803	Belongs to the bacterial solute-binding protein 9 family
EFD32_RS14335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFD32_RS14340	COG0842	Transport permease protein
EFD32_RS14345	COG1131	(ABC) transporter
EFD32_RS14360	COG3715	PTS system
EFD32_RS14365	COG3716	PTS system mannose fructose sorbose family IID component
EFD32_RS14380	COG1368	sulfuric ester hydrolase activity
EFD32_RS14385	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EFD32_RS14390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFD32_RS14395	COG0783	Belongs to the Dps family
EFD32_RS14405	COG1070	Carbohydrate kinase
EFD32_RS14410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EFD32_RS14415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFD32_RS14420	COG0085	RNA polymerase activity
EFD32_RS14445	COG3397	chitin binding
EFD32_RS14455	COG1316	TRANSCRIPTIONal
EFD32_RS14485	COG1575	Belongs to the MenA family. Type 1 subfamily
EFD32_RS14495	COG4939	FMN-binding domain protein
EFD32_RS14515	COG0142	geranyltranstransferase activity
EFD32_RS14535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EFD32_RS14540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFD32_RS14545	COG0302	gtp cyclohydrolase
EFD32_RS14555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFD32_RS14600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFD32_RS14630	COG2508	Transcriptional regulator
EFD32_RS14630	COG2508	Transcriptional regulator
EFD32_RS14635	COG0826	peptidase U32
EFD32_RS14640	COG0826	peptidase U32
EFD32_RS14650	COG0542	response to heat
EFD32_RS14655	COG4463	regulation of RNA biosynthetic process
EFD32_RS14660	COG0626	cystathionine gamma-synthase activity
EFD32_RS14665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EFD32_RS14670	COG1737	Transcriptional regulator
EFD32_RS14745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFD32_RS14750	COG0516	GMP reductase activity
EFD32_RS14750	COG0517	IMP dehydrogenase activity
EFD32_RS14765	COG0012	GTP binding
EFD32_RS14770	COG4481	Protein conserved in bacteria
EFD32_RS14775	COG1475	DNA binding
EFD32_RS14780	COG1192	Involved in chromosome partitioning
EFD32_RS14785	COG0357	Ribosomal RNA small subunit methyltransferase G
EFD32_RS14815	COG3732	PTS system glucitol sorbitol-specific
EFD32_RS14820	COG3730	PTS system glucitol sorbitol-specific
EFD32_RS14840	COG0445	tRNA wobble uridine modification
EFD32_RS14845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFD32_RS14860	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EFD32_RS14890	COG3052	prosthetic group binding
EFD32_RS14895	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EFD32_RS14905	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EFD32_RS14910	COG0511	ligase activity, forming carbon-carbon bonds
EFD32_RS14920	COG2851	Citrate transporter
EFD32_RS14930	COG0745	RESPONSE REGULATOR receiver
EFD32_RS14975	COG0706	membrane insertase activity
EFD32_RS14980	COG0594	ribonuclease P activity
EFD32_RS14985	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EFD32_RS15000	COG0592	DNA-directed DNA polymerase activity
EFD32_RS15015	COG0187	DNA topoisomerase II activity
EFD32_RS15025	COG0187	DNA topoisomerase II activity
EFD32_RS15030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFD32_RS15085	COG0187	DNA topoisomerase II activity
EFD32_RS15095	COG0187	DNA topoisomerase II activity
EFD32_RS15250	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EFD32_RS15250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EFD32_RS15510	COG3942	CHAP domain
EFD32_RS15510	COG1705	Flagellar rod assembly protein muramidase FlgJ