locus-tag	class	description
SAW_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SAW_RS00010	COG0592	DNA-directed DNA polymerase activity
SAW_RS00015	COG2501	S4 domain
SAW_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SAW_RS00025	COG0187	DNA topoisomerase II activity
SAW_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
SAW_RS00040	COG0629	single-stranded DNA binding
SAW_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SAW_RS00055	COG0359	binds to the 23S rRNA
SAW_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
SAW_RS00065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SAW_RS00075	COG0488	(ABC) transporter
SAW_RS00080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SAW_RS00080	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SAW_RS00085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS00085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS00095	COG3715	PTS system
SAW_RS00100	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS00125	COG1737	Transcriptional regulator
SAW_RS00130	COG1263	PTS System
SAW_RS00130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS00135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAW_RS00140	COG0251	oxidation-reduction process
SAW_RS00145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAW_RS00145	COG0392	lysyltransferase activity
SAW_RS00175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SAW_RS00180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAW_RS00185	COG0756	dUTP diphosphatase activity
SAW_RS00195	COG4956	integral membrane protein (PIN domain superfamily)
SAW_RS00200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SAW_RS00205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SAW_RS00215	COG1045	serine acetyltransferase
SAW_RS00220	COG0215	cysteine-tRNA ligase activity
SAW_RS00225	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAW_RS00230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAW_RS00235	COG3688	RNA-binding protein containing a PIN domain
SAW_RS00245	COG4466	Protein conserved in bacteria
SAW_RS00250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SAW_RS00260	COG2176	DNA-directed DNA polymerase activity
SAW_RS00275	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAW_RS00275	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAW_RS00280	COG1121	(ABC) transporter
SAW_RS00285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAW_RS00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAW_RS00295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SAW_RS00300	COG0737	Belongs to the 5'-nucleotidase family
SAW_RS00305	COG4166	transmembrane transport
SAW_RS00310	COG4224	UPF0291 protein
SAW_RS00315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAW_RS00320	COG0632	four-way junction helicase activity
SAW_RS00325	COG2255	four-way junction helicase activity
SAW_RS00335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SAW_RS00340	COG3408	Glycogen debranching enzyme
SAW_RS00340	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SAW_RS00350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAW_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS00380	COG2261	transglycosylase associated protein
SAW_RS00385	COG2814	Major facilitator Superfamily
SAW_RS00415	COG1597	lipid kinase activity
SAW_RS00440	COG2116	formate transmembrane transporter activity
SAW_RS00450	COG2964	Protein conserved in bacteria
SAW_RS00460	COG1760	l-serine dehydratase
SAW_RS00465	COG1760	l-serine dehydratase
SAW_RS00470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAW_RS00480	COG1438	arginine binding
SAW_RS00485	COG1438	arginine binding
SAW_RS00490	COG2235	arginine
SAW_RS00495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAW_RS00500	COG0549	Belongs to the carbamate kinase family
SAW_RS00510	COG1288	antiporter activity
SAW_RS00520	COG0640	Transcriptional regulator
SAW_RS00525	COG0604	alcohol dehydrogenase
SAW_RS00535	COG1475	DNA binding
SAW_RS00545	COG0251	oxidation-reduction process
SAW_RS00555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAW_RS00605	COG0519	Catalyzes the synthesis of GMP from XMP
SAW_RS00605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SAW_RS00610	COG1072	(Pantothenic acid kinase))
SAW_RS00620	COG2813	Specifically methylates the guanine in position
SAW_RS00625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAW_RS00630	COG1609	Transcriptional regulator
SAW_RS00635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SAW_RS00640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SAW_RS00645	COG0295	cytidine deaminase activity
SAW_RS00650	COG1744	ABC transporter substrate-binding protein PnrA-like
SAW_RS00655	COG1744	ABC transporter substrate-binding protein PnrA-like
SAW_RS00660	COG3845	ABC transporter
SAW_RS00665	COG4603	Belongs to the binding-protein-dependent transport system permease family
SAW_RS00670	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAW_RS00690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SAW_RS00705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAW_RS00710	COG1120	ATPase activity
SAW_RS00715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAW_RS00720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAW_RS00725	COG1979	alcohol dehydrogenase
SAW_RS00730	COG0588	phosphoglycerate mutase activity
SAW_RS00735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAW_RS00740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SAW_RS00750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SAW_RS00755	COG0049	tRNA binding
SAW_RS00760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SAW_RS00765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SAW_RS00770	COG0351	phosphomethylpyrimidine kinase
SAW_RS00775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAW_RS00780	COG0051	transcription antitermination factor activity, RNA binding
SAW_RS00785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SAW_RS00790	COG0088	Forms part of the polypeptide exit tunnel
SAW_RS00795	COG0089	rRNA binding
SAW_RS00800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SAW_RS00805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SAW_RS00810	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SAW_RS00815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SAW_RS00820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SAW_RS00825	COG0255	Belongs to the universal ribosomal protein uL29 family
SAW_RS00830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SAW_RS00835	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SAW_RS00840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SAW_RS00845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SAW_RS00850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SAW_RS00855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SAW_RS00860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SAW_RS00865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SAW_RS00870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SAW_RS00875	COG1841	ribosomal large subunit assembly
SAW_RS00880	COG0200	Binds to the 23S rRNA
SAW_RS00885	COG0201	protein transport
SAW_RS00890	COG0563	adenylate kinase activity
SAW_RS00895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SAW_RS00900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SAW_RS00905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAW_RS00910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SAW_RS00915	COG0202	RNA polymerase activity
SAW_RS00920	COG0203	ribosomal protein L17
SAW_RS00935	COG1473	amidohydrolase
SAW_RS00940	COG1122	ATPase activity
SAW_RS00945	COG1122	ATPase activity
SAW_RS00960	COG0393	Putative heavy-metal-binding
SAW_RS00965	COG1114	Component of the transport system for branched-chain amino acids
SAW_RS00980	COG1126	abc transporter atp-binding protein
SAW_RS00985	COG0765	amino acid transport
SAW_RS00995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SAW_RS01000	COG0110	maltose O-acetyltransferase activity
SAW_RS01005	COG1827	regulation of RNA biosynthetic process
SAW_RS01010	COG3942	CHAP domain
SAW_RS01010	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS01025	COG0039	L-malate dehydrogenase activity
SAW_RS01030	COG0193	aminoacyl-tRNA hydrolase activity
SAW_RS01035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SAW_RS01040	COG2244	polysaccharide biosynthetic process
SAW_RS01045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAW_RS01060	COG1098	S1 RNA binding domain
SAW_RS01065	COG0037	tRNA processing
SAW_RS01070	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SAW_RS01075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAW_RS01080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SAW_RS01085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAW_RS01090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SAW_RS01245	COG3711	transcriptional antiterminator
SAW_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS01250	COG1263	PTS System
SAW_RS01250	COG2190	(PTS) system
SAW_RS01255	COG2723	6-phospho-beta-galactosidase activity
SAW_RS01260	COG2723	6-phospho-beta-galactosidase activity
SAW_RS01270	COG0596	Alpha beta hydrolase
SAW_RS01275	COG2169	Transcriptional regulator
SAW_RS01280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAW_RS01285	COG0519	Catalyzes the synthesis of GMP from XMP
SAW_RS01290	COG1418	mRNA catabolic process
SAW_RS01305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SAW_RS01310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAW_RS01315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAW_RS01320	COG0167	dihydroorotate dehydrogenase activity
SAW_RS01330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAW_RS01340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAW_RS01345	COG0626	cystathionine gamma-synthase activity
SAW_RS01350	COG2723	6-phospho-beta-galactosidase activity
SAW_RS01355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS01365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAW_RS01370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAW_RS01385	COG2217	Heavy metal translocating P-type atpase
SAW_RS01400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAW_RS01405	COG3579	cysteine-type endopeptidase activity
SAW_RS01410	COG0582	viral genome integration into host DNA
SAW_RS01425	COG1396	sequence-specific DNA binding
SAW_RS01580	COG2369	cell adhesion
SAW_RS01680	COG1388	LysM domain
SAW_RS01680	COG3942	CHAP domain
SAW_RS01695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAW_RS01700	COG0346	lactoylglutathione lyase activity
SAW_RS01705	COG2076	Multidrug Resistance protein
SAW_RS01710	COG2076	Multidrug Resistance protein
SAW_RS01715	COG3469	chitinase activity
SAW_RS01720	COG3397	chitin binding
SAW_RS01730	COG1801	Protein of unknown function DUF72
SAW_RS01740	COG0527	aspartate kinase activity
SAW_RS01745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAW_RS01750	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SAW_RS01755	COG1104	cysteine desulfurase activity
SAW_RS01760	COG0745	RESPONSE REGULATOR receiver
SAW_RS01765	COG5002	protein histidine kinase activity
SAW_RS01785	COG0666	response to abiotic stimulus
SAW_RS01810	COG3835	regulator
SAW_RS01815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SAW_RS01830	COG0549	Belongs to the carbamate kinase family
SAW_RS01840	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SAW_RS01870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SAW_RS01875	COG0628	permease
SAW_RS01900	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SAW_RS01910	COG1757	Na H antiporter
SAW_RS01915	COG1846	Transcriptional regulator
SAW_RS01920	COG0778	Nitroreductase
SAW_RS01925	COG0561	phosphatase activity
SAW_RS01940	COG3711	transcriptional antiterminator
SAW_RS01945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS01955	COG2213	PTS system mannitol-specific
SAW_RS01960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS01965	COG0246	Mannitol dehydrogenase
SAW_RS01970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAW_RS01985	COG0577	efflux transmembrane transporter activity
SAW_RS01985	COG1136	(ABC) transporter
SAW_RS01990	COG0577	efflux transmembrane transporter activity
SAW_RS02000	COG2814	Major facilitator Superfamily
SAW_RS02010	COG1414	Transcriptional regulator
SAW_RS02030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SAW_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS02040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAW_RS02065	COG1070	Carbohydrate kinase
SAW_RS02070	COG4806	L-rhamnose isomerase
SAW_RS02075	COG0235	Class ii aldolase
SAW_RS02080	COG3254	rhamnose metabolic process
SAW_RS02100	COG3104	oligopeptide transport
SAW_RS02115	COG1388	LysM domain
SAW_RS02115	COG3942	CHAP domain
SAW_RS02125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SAW_RS02130	COG0318	PFAM AMP-dependent synthetase and ligase
SAW_RS02135	COG1169	isochorismate synthase
SAW_RS02140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SAW_RS02145	COG2267	carboxylic ester hydrolase activity
SAW_RS02150	COG4948	Mandelate Racemase Muconate Lactonizing
SAW_RS02155	COG0363	glucosamine-6-phosphate deaminase activity
SAW_RS02160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAW_RS02165	COG1764	response to oxidative stress
SAW_RS02180	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS02185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS02195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SAW_RS02200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAW_RS02215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAW_RS02220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SAW_RS02225	COG1316	TRANSCRIPTIONal
SAW_RS02230	COG0363	glucosamine-6-phosphate deaminase activity
SAW_RS02235	COG1285	pathogenesis
SAW_RS02255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAW_RS02260	COG1780	Probably involved in ribonucleotide reductase function
SAW_RS02265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAW_RS02290	COG0582	viral genome integration into host DNA
SAW_RS02320	COG1191	sigma factor activity
SAW_RS02360	COG1388	LysM domain
SAW_RS02360	COG3942	CHAP domain
SAW_RS02415	COG0629	single-stranded DNA binding
SAW_RS02470	COG0629	single-stranded DNA binding
SAW_RS02475	COG1525	nuclease
SAW_RS02485	COG3041	Addiction module toxin RelE StbE family
SAW_RS02505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAW_RS02530	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SAW_RS02620	COG3328	transposase activity
SAW_RS02625	COG2207	Transcriptional regulator
SAW_RS02625	COG1917	Cupin 2, conserved barrel domain protein
SAW_RS02670	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SAW_RS02675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS02675	COG1263	PTS System
SAW_RS02675	COG2190	(PTS) system
SAW_RS02680	COG2190	(PTS) system
SAW_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS02680	COG1263	PTS System
SAW_RS02695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SAW_RS02725	COG2801	Transposase and inactivated derivatives
SAW_RS02750	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS02755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS02755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS02765	COG2115	Belongs to the xylose isomerase family
SAW_RS02770	COG1070	Carbohydrate kinase
SAW_RS02775	COG2244	polysaccharide biosynthetic process
SAW_RS02820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SAW_RS02825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SAW_RS02830	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SAW_RS02835	COG2205	protein histidine kinase activity
SAW_RS02895	COG1309	transcriptional regulator
SAW_RS02905	COG1129	ABC transporter
SAW_RS02915	COG1132	(ABC) transporter
SAW_RS02920	COG1132	(ABC) transporter
SAW_RS02925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SAW_RS02930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SAW_RS02940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAW_RS02950	COG0726	polysaccharide deacetylase
SAW_RS03035	COG1475	DNA binding
SAW_RS03045	COG3969	phosphoadenosine phosphosulfate
SAW_RS03090	COG1378	Sugar-specific transcriptional regulator TrmB
SAW_RS03120	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS03140	COG0656	L-ascorbic acid biosynthetic process
SAW_RS03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SAW_RS03165	COG1113	amino acid transport
SAW_RS03170	COG1757	Na H antiporter
SAW_RS03185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SAW_RS03195	COG0039	L-malate dehydrogenase activity
SAW_RS03210	COG0583	DNA-binding transcription factor activity
SAW_RS03225	COG1733	regulation of RNA biosynthetic process
SAW_RS03230	COG0778	Nitroreductase
SAW_RS03235	COG0095	Lipoate-protein ligase
SAW_RS03255	COG1609	Transcriptional regulator
SAW_RS03265	COG2514	catechol 2,3-dioxygenase activity
SAW_RS03270	COG1349	DNA-binding transcription factor activity
SAW_RS03285	COG0534	Mate efflux family protein
SAW_RS03300	COG0217	transcriptional regulatory protein
SAW_RS03315	COG0346	lactoylglutathione lyase activity
SAW_RS03325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SAW_RS03330	COG2244	polysaccharide biosynthetic process
SAW_RS03335	COG1187	pseudouridine synthase activity
SAW_RS03350	COG3594	Acyltransferase
SAW_RS03355	COG0517	IMP dehydrogenase activity
SAW_RS03355	COG1125	glycine betaine transport
SAW_RS03360	COG1732	Glycine betaine
SAW_RS03365	COG1438	arginine binding
SAW_RS03370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAW_RS03375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAW_RS03380	COG0564	pseudouridine synthase activity
SAW_RS03385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAW_RS03390	COG3679	Belongs to the UPF0342 family
SAW_RS03405	COG3481	metal-dependent phosphohydrolase, HD sub domain
SAW_RS03410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SAW_RS03420	COG0537	adenosine 5'-monophosphoramidase activity
SAW_RS03425	COG1131	(ABC) transporter
SAW_RS03430	COG4473	ABC transporter
SAW_RS03435	COG0510	thiamine kinase activity
SAW_RS03440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAW_RS03455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAW_RS03455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS03455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAW_RS03465	COG3684	Belongs to the aldolase LacD family
SAW_RS03470	COG3557	Belongs to the UPF0374 family
SAW_RS03480	COG0628	permease
SAW_RS03485	COG1253	flavin adenine dinucleotide binding
SAW_RS03490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SAW_RS03515	COG0542	response to heat
SAW_RS03530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS03535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAW_RS03555	COG0544	peptidyl-prolyl cis-trans isomerase activity
SAW_RS03565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAW_RS03565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS03565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAW_RS03570	COG1105	Belongs to the carbohydrate kinase PfkB family
SAW_RS03575	COG1349	DNA-binding transcription factor activity
SAW_RS03585	COG0210	DNA helicase
SAW_RS03590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SAW_RS03600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SAW_RS03605	COG0154	amidase activity
SAW_RS03610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SAW_RS03615	COG1597	lipid kinase activity
SAW_RS03620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAW_RS03630	COG2197	response regulator
SAW_RS03635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAW_RS03640	COG0531	amino acid
SAW_RS03645	COG2957	Belongs to the agmatine deiminase family
SAW_RS03650	COG0549	Belongs to the carbamate kinase family
SAW_RS03655	COG0154	amidase activity
SAW_RS03670	COG1428	Deoxynucleoside kinase
SAW_RS03700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAW_RS03715	COG1054	Belongs to the UPF0176 family
SAW_RS03760	COG2217	Heavy metal translocating P-type atpase
SAW_RS03765	COG1285	pathogenesis
SAW_RS03775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAW_RS03780	COG0556	nucleotide-excision repair
SAW_RS03785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SAW_RS03795	COG1660	Displays ATPase and GTPase activities
SAW_RS03805	COG1481	regulation of sporulation
SAW_RS03820	COG0740	serine-type endopeptidase activity
SAW_RS03850	COG0584	glycerophosphoryl diester phosphodiesterase
SAW_RS03855	COG2816	NAD+ diphosphatase activity
SAW_RS03860	COG1278	Cold shock
SAW_RS03870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SAW_RS03875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAW_RS03875	COG2755	lipolytic protein G-D-S-L family
SAW_RS03880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAW_RS03885	COG0477	Major facilitator Superfamily
SAW_RS03900	COG1132	(ABC) transporter
SAW_RS03905	COG1132	(ABC) transporter
SAW_RS03920	COG1309	transcriptional regulator
SAW_RS03925	COG0577	efflux transmembrane transporter activity
SAW_RS03930	COG1136	(ABC) transporter
SAW_RS03935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAW_RS03940	COG1242	4 iron, 4 sulfur cluster binding
SAW_RS03945	COG0671	phosphoesterase, PA-phosphatase related
SAW_RS03960	COG1388	LysM domain
SAW_RS03960	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS03965	COG0495	leucyl-tRNA aminoacylation
SAW_RS03980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAW_RS03985	COG1126	abc transporter atp-binding protein
SAW_RS03990	COG0765	amino acid transport
SAW_RS03995	COG4166	transmembrane transport
SAW_RS04020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAW_RS04030	COG2188	Transcriptional regulator
SAW_RS04035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS04035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS04060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SAW_RS04070	COG1187	pseudouridine synthase activity
SAW_RS04075	COG1011	Hydrolase
SAW_RS04095	COG2337	Toxic component of a toxin-antitoxin (TA) module
SAW_RS04100	COG0673	inositol 2-dehydrogenase activity
SAW_RS04105	COG3711	transcriptional antiterminator
SAW_RS04135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS04150	COG3964	amidohydrolase
SAW_RS04170	COG0187	DNA topoisomerase II activity
SAW_RS04175	COG1671	Belongs to the UPF0178 family
SAW_RS04180	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAW_RS04185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAW_RS04205	COG0736	holo-[acyl-carrier-protein] synthase activity
SAW_RS04210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SAW_RS04215	COG2337	Toxic component of a toxin-antitoxin (TA) module
SAW_RS04235	COG0681	Belongs to the peptidase S26 family
SAW_RS04245	COG2365	Tyrosine phosphatase family
SAW_RS04265	COG0531	amino acid
SAW_RS04275	COG1174	glycine betaine transport
SAW_RS04295	COG0346	lactoylglutathione lyase activity
SAW_RS04300	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SAW_RS04320	COG3158	transport of potassium into the cell
SAW_RS04330	COG2217	Heavy metal translocating P-type atpase
SAW_RS04340	COG4989	oxidoreductase activity
SAW_RS04345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAW_RS04345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAW_RS04350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAW_RS04355	COG0237	dephospho-CoA kinase activity
SAW_RS04360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SAW_RS04365	COG3611	Membrane attachment protein
SAW_RS04370	COG1484	DNA-dependent DNA replication
SAW_RS04390	COG1215	transferase activity, transferring glycosyl groups
SAW_RS04415	COG1126	abc transporter atp-binding protein
SAW_RS04420	COG0765	amino acid transport
SAW_RS04425	COG0371	Dehydrogenase
SAW_RS04430	COG0343	queuine tRNA-ribosyltransferase activity
SAW_RS04435	COG1862	Preprotein translocase
SAW_RS04455	COG1012	belongs to the aldehyde dehydrogenase family
SAW_RS04455	COG1454	alcohol dehydrogenase
SAW_RS04460	COG1304	FMN binding
SAW_RS04495	COG4166	transmembrane transport
SAW_RS04505	COG0601	transmembrane transport
SAW_RS04510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAW_RS04515	COG0444	Belongs to the ABC transporter superfamily
SAW_RS04520	COG4608	Belongs to the ABC transporter superfamily
SAW_RS04530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAW_RS04535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SAW_RS04540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAW_RS04555	COG3759	membrane
SAW_RS04565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SAW_RS04565	COG0456	acetyltransferase
SAW_RS04570	COG0659	secondary active sulfate transmembrane transporter activity
SAW_RS04580	COG2855	membrane
SAW_RS04600	COG0745	RESPONSE REGULATOR receiver
SAW_RS04605	COG2205	protein histidine kinase activity
SAW_RS04610	COG4975	Glucose uptake
SAW_RS04615	COG0531	amino acid
SAW_RS04620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAW_RS04620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAW_RS04635	COG3973	AAA domain
SAW_RS04640	COG0084	hydrolase, TatD family'
SAW_RS04645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAW_RS04650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SAW_RS04660	COG3842	ATPase activity
SAW_RS04665	COG1803	Methylglyoxal synthase
SAW_RS04670	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAW_RS04675	COG1132	(ABC) transporter
SAW_RS04690	COG3584	3D domain protein
SAW_RS04705	COG0561	phosphatase activity
SAW_RS04710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAW_RS04715	COG0280	phosphate acetyltransferase
SAW_RS04720	COG0802	atpase or kinase
SAW_RS04725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAW_RS04735	COG1609	Transcriptional regulator
SAW_RS04740	COG2017	converts alpha-aldose to the beta-anomer
SAW_RS04745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAW_RS04755	COG1263	PTS System
SAW_RS04755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS04755	COG2190	(PTS) system
SAW_RS04770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAW_RS04795	COG0789	Transcriptional regulator
SAW_RS04810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SAW_RS04820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SAW_RS04825	COG3223	Belongs to the PsiE family
SAW_RS04830	COG1408	metallophosphoesterase
SAW_RS04835	COG0006	proline dipeptidase activity
SAW_RS04840	COG1694	Mazg nucleotide pyrophosphohydrolase
SAW_RS04845	COG1302	Protein conserved in bacteria
SAW_RS04850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAW_RS04855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SAW_RS04860	COG1570	exodeoxyribonuclease VII activity
SAW_RS04865	COG1722	exodeoxyribonuclease VII activity
SAW_RS04870	COG0142	geranyltranstransferase activity
SAW_RS04875	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SAW_RS04880	COG1438	arginine binding
SAW_RS04885	COG0497	DNA recombination
SAW_RS04910	COG2001	Belongs to the MraZ family
SAW_RS04915	COG0275	rRNA processing
SAW_RS04925	COG0768	penicillin binding
SAW_RS04930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAW_RS04935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SAW_RS04940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAW_RS04945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAW_RS04950	COG0849	cell division
SAW_RS04955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SAW_RS04960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAW_RS04965	COG1799	cell septum assembly
SAW_RS04970	COG0762	integral membrane protein
SAW_RS04975	COG2302	S4 RNA-binding domain
SAW_RS04980	COG3599	regulation of cell shape
SAW_RS04985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SAW_RS04990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAW_RS05010	COG0673	inositol 2-dehydrogenase activity
SAW_RS05020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SAW_RS05020	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SAW_RS05025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05055	COG1447	Phosphotransferase system cellobiose-specific component IIA
SAW_RS05060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05065	COG2723	6-phospho-beta-galactosidase activity
SAW_RS05090	COG0574	Belongs to the PEP-utilizing enzyme family
SAW_RS05090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAW_RS05095	COG0517	IMP dehydrogenase activity
SAW_RS05100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SAW_RS05105	COG0392	lysyltransferase activity
SAW_RS05105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAW_RS05150	COG0105	UTP biosynthetic process
SAW_RS05165	COG0561	phosphatase activity
SAW_RS05175	COG2252	PERMEase
SAW_RS05185	COG2814	Major facilitator Superfamily
SAW_RS05195	COG0587	DNA-directed DNA polymerase activity
SAW_RS05200	COG0205	6-phosphofructokinase activity
SAW_RS05215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SAW_RS05220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SAW_RS05225	COG0745	RESPONSE REGULATOR receiver
SAW_RS05230	COG5002	protein histidine kinase activity
SAW_RS05330	COG1116	anion transmembrane transporter activity
SAW_RS05335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAW_RS05340	COG1660	Displays ATPase and GTPase activities
SAW_RS05350	COG1914	H( )-stimulated, divalent metal cation uptake system
SAW_RS05360	COG2508	Transcriptional regulator
SAW_RS05365	COG4166	transmembrane transport
SAW_RS05370	COG0402	S-adenosylhomocysteine deaminase activity
SAW_RS05375	COG0402	S-adenosylhomocysteine deaminase activity
SAW_RS05380	COG1956	GAF domain-containing protein
SAW_RS05395	COG0110	maltose O-acetyltransferase activity
SAW_RS05410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SAW_RS05415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAW_RS05420	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SAW_RS05425	COG1609	Transcriptional regulator
SAW_RS05430	COG0572	uridine kinase
SAW_RS05455	COG2814	Major facilitator Superfamily
SAW_RS05465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAW_RS05495	COG0456	acetyltransferase
SAW_RS05570	COG1132	(ABC) transporter
SAW_RS05585	COG1113	amino acid transport
SAW_RS05605	COG0247	lactate metabolic process
SAW_RS05610	COG1139	Iron-sulfur cluster binding protein
SAW_RS05625	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SAW_RS05630	COG1074	ATP-dependent DNA helicase activity
SAW_RS05635	COG1733	regulation of RNA biosynthetic process
SAW_RS05640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SAW_RS05645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAW_RS05645	COG0072	phenylalanine-tRNA ligase activity
SAW_RS05650	COG0765	amino acid transport
SAW_RS05655	COG0765	amino acid transport
SAW_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAW_RS05670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SAW_RS05675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SAW_RS05680	COG0622	Phosphoesterase
SAW_RS05685	COG1349	DNA-binding transcription factor activity
SAW_RS05695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS05700	COG3037	sugar-specific permease SgaT UlaA
SAW_RS05710	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SAW_RS05715	COG3623	hexulose-6-phosphate isomerase
SAW_RS05725	COG0517	IMP dehydrogenase activity
SAW_RS05730	COG2171	N-acyltransferase activity
SAW_RS05735	COG1473	amidohydrolase
SAW_RS05740	COG0668	transmembrane transport
SAW_RS05755	COG0656	L-ascorbic acid biosynthetic process
SAW_RS05760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAW_RS05780	COG1078	dGTPase activity
SAW_RS05785	COG0095	Lipoate-protein ligase
SAW_RS05800	COG0504	CTP synthase activity
SAW_RS05805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAW_RS05810	COG3331	DNA recombination
SAW_RS05815	COG4474	Belongs to the UPF0398 family
SAW_RS05820	COG3599	regulation of cell shape
SAW_RS05830	COG0116	Belongs to the methyltransferase superfamily
SAW_RS05835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SAW_RS05840	COG3935	DnaD domain protein
SAW_RS05845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAW_RS05850	COG2188	Transcriptional regulator
SAW_RS05860	COG1446	asparaginase
SAW_RS05865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS05895	COG1666	GTP binding
SAW_RS05900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAW_RS05905	COG0191	fructose-bisphosphate aldolase activity
SAW_RS05915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SAW_RS05920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAW_RS05925	COG0254	rRNA binding
SAW_RS05935	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAW_RS05945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAW_RS05960	COG1940	carbohydrate kinase activity
SAW_RS05965	COG3237	CsbD-like
SAW_RS05970	COG0778	Nitroreductase
SAW_RS05975	COG1854	S-ribosylhomocysteine lyase activity
SAW_RS05980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAW_RS05985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAW_RS05995	COG0737	Belongs to the 5'-nucleotidase family
SAW_RS06000	COG4470	Protein conserved in bacteria
SAW_RS06005	COG0647	UMP catabolic process
SAW_RS06020	COG1307	EDD domain protein, DegV family
SAW_RS06025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAW_RS06030	COG0745	RESPONSE REGULATOR receiver
SAW_RS06035	COG5002	protein histidine kinase activity
SAW_RS06050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAW_RS06060	COG0701	Predicted permease
SAW_RS06065	COG3689	TIGRFAM TIGR03943 family protein
SAW_RS06080	COG4472	Bacterial protein of unknown function (DUF965)
SAW_RS06085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAW_RS06090	COG3906	Belongs to the UPF0473 family
SAW_RS06105	COG3493	citrate carrier protein
SAW_RS06110	COG3290	protein histidine kinase activity
SAW_RS06115	COG4565	transcriptional regulatory protein
SAW_RS06120	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAW_RS06125	COG1316	TRANSCRIPTIONal
SAW_RS06130	COG0028	Belongs to the TPP enzyme family
SAW_RS06135	COG3527	Alpha-acetolactate decarboxylase
SAW_RS06155	COG1175	transmembrane transport
SAW_RS06165	COG3842	ATPase activity
SAW_RS06175	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SAW_RS06200	COG1053	succinate dehydrogenase
SAW_RS06200	COG3976	FMN-binding domain protein
SAW_RS06200	COG0431	NADPH-dependent FMN reductase
SAW_RS06220	COG1408	metallophosphoesterase
SAW_RS06225	COG4209	transmembrane transport
SAW_RS06230	COG0395	ABC-type sugar transport system, permease component
SAW_RS06245	COG3458	cephalosporin-C deacetylase activity
SAW_RS06260	COG3459	Glycosyltransferase 36 associated
SAW_RS06265	COG1609	Transcriptional regulator
SAW_RS06275	COG2188	Transcriptional regulator
SAW_RS06280	COG2723	6-phospho-beta-galactosidase activity
SAW_RS06285	COG0673	inositol 2-dehydrogenase activity
SAW_RS06290	COG2707	UPF0756 membrane protein
SAW_RS06305	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAW_RS06335	COG1122	ATPase activity
SAW_RS06355	COG0561	phosphatase activity
SAW_RS06360	COG0745	RESPONSE REGULATOR receiver
SAW_RS06365	COG5002	protein histidine kinase activity
SAW_RS06365	COG3850	Histidine kinase
SAW_RS06380	COG1368	sulfuric ester hydrolase activity
SAW_RS06385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAW_RS06395	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SAW_RS06400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAW_RS06405	COG4932	domain protein
SAW_RS06405	COG1388	LysM domain
SAW_RS06410	COG0779	Required for maturation of 30S ribosomal subunits
SAW_RS06415	COG0195	Participates in both transcription termination and antitermination
SAW_RS06420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAW_RS06430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SAW_RS06435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAW_RS06525	COG4824	toxin secretion phage lysis holin
SAW_RS06535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAW_RS06540	COG0196	riboflavin kinase activity
SAW_RS06550	COG1695	Transcriptional regulator
SAW_RS06570	COG0772	Belongs to the SEDS family
SAW_RS06575	COG0583	DNA-binding transcription factor activity
SAW_RS06580	COG0583	DNA-binding transcription factor activity
SAW_RS06590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAW_RS06595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAW_RS06600	COG1420	regulation of RNA biosynthetic process
SAW_RS06605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SAW_RS06610	COG0443	Heat shock 70 kDa protein
SAW_RS06620	COG0484	heat shock protein binding
SAW_RS06630	COG2183	response to ionizing radiation
SAW_RS06635	COG3091	SprT-like family
SAW_RS06645	COG0436	Aminotransferase
SAW_RS06695	COG2268	Band 7 protein
SAW_RS06720	COG1309	transcriptional regulator
SAW_RS06730	COG2188	Transcriptional regulator
SAW_RS06735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAW_RS06755	COG1131	(ABC) transporter
SAW_RS06765	COG3290	protein histidine kinase activity
SAW_RS06775	COG3279	Response regulator of the LytR AlgR family
SAW_RS06785	COG0492	ferredoxin-NADP+ reductase activity
SAW_RS06800	COG1136	(ABC) transporter
SAW_RS06800	COG0577	efflux transmembrane transporter activity
SAW_RS06800	COG1136	(ABC) transporter
SAW_RS06800	COG0577	efflux transmembrane transporter activity
SAW_RS06810	COG3833	ABC-type maltose transport systems, permease component
SAW_RS06815	COG1175	transmembrane transport
SAW_RS06820	COG2182	Extracellular solute-binding protein
SAW_RS06830	COG0366	Alpha amylase catalytic
SAW_RS06835	COG0366	Alpha amylase catalytic
SAW_RS06840	COG0366	Alpha amylase catalytic
SAW_RS06855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAW_RS06885	COG0371	Dehydrogenase
SAW_RS06895	COG2376	Dihydroxyacetone kinase
SAW_RS06900	COG1461	Dihydroxyacetone kinase
SAW_RS06910	COG3425	synthase
SAW_RS06920	COG0628	permease
SAW_RS06930	COG1278	Cold shock
SAW_RS06945	COG2814	Major facilitator Superfamily
SAW_RS06950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SAW_RS06955	COG4109	DRTGG domain
SAW_RS06960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAW_RS06965	COG2824	Alkylphosphonate utilization operon protein PhnA
SAW_RS06980	COG0513	Belongs to the DEAD box helicase family
SAW_RS06990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SAW_RS06995	COG2384	SAM-dependent methyltransferase
SAW_RS07000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SAW_RS07005	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAW_RS07020	COG0746	molybdenum cofactor guanylyltransferase activity
SAW_RS07025	COG2116	formate transmembrane transporter activity
SAW_RS07040	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SAW_RS07045	COG3383	formate dehydrogenase (NAD+) activity
SAW_RS07050	COG0303	'Molybdopterin
SAW_RS07060	COG0315	cyclic pyranopterin monophosphate synthase activity
SAW_RS07075	COG0521	Mo-molybdopterin cofactor biosynthetic process
SAW_RS07085	COG0725	ABC transporter, periplasmic molybdate-binding protein
SAW_RS07090	COG4149	molybdate abc transporter
SAW_RS07095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAW_RS07100	COG2217	Heavy metal translocating P-type atpase
SAW_RS07120	COG1286	toxin biosynthetic process
SAW_RS07125	COG1193	negative regulation of DNA recombination
SAW_RS07130	COG3118	belongs to the thioredoxin family
SAW_RS07135	COG0322	excinuclease ABC activity
SAW_RS07145	COG4152	abc transporter atp-binding protein
SAW_RS07150	COG1668	transmembrane transport
SAW_RS07155	COG1609	Transcriptional regulator
SAW_RS07160	COG1486	melibiose metabolic process
SAW_RS07170	COG0488	(ABC) transporter
SAW_RS07175	COG2081	HI0933 family
SAW_RS07180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAW_RS07185	COG0166	Belongs to the GPI family
SAW_RS07190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SAW_RS07215	COG1396	sequence-specific DNA binding
SAW_RS07270	COG3935	DnaD domain protein
SAW_RS07370	COG0863	Belongs to the N(4) N(6)-methyltransferase family
SAW_RS07380	COG3728	DNA packaging
SAW_RS07380	COG5484	DNA packaging
SAW_RS07395	COG2369	cell adhesion
SAW_RS07570	COG1269	ATP hydrolysis coupled proton transport
SAW_RS07575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SAW_RS07580	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
SAW_RS07585	COG1527	subunit (C
SAW_RS07590	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SAW_RS07595	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SAW_RS07600	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SAW_RS07605	COG1394	ATPase activity, coupled to movement of substances
SAW_RS07620	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SAW_RS07625	COG0019	diaminopimelate decarboxylase activity
SAW_RS07655	COG2151	metal-sulfur cluster biosynthetic enzyme
SAW_RS07660	COG4948	Mandelate Racemase Muconate Lactonizing
SAW_RS07670	COG4166	transmembrane transport
SAW_RS07675	COG3711	transcriptional antiterminator
SAW_RS07690	COG0741	lytic transglycosylase activity
SAW_RS07695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAW_RS07700	COG0358	DNA primase activity
SAW_RS07705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAW_RS07715	COG2996	Protein conserved in bacteria
SAW_RS07720	COG0735	belongs to the Fur family
SAW_RS07730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SAW_RS07740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS07755	COG5294	Protein conserved in bacteria
SAW_RS07760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAW_RS07775	COG4974	Belongs to the 'phage' integrase family
SAW_RS07780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SAW_RS07785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SAW_RS07790	COG1187	pseudouridine synthase activity
SAW_RS07795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SAW_RS07815	COG0514	ATP-dependent DNA helicase (RecQ)
SAW_RS07825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SAW_RS07830	COG0539	negative regulation of cytoplasmic translation
SAW_RS07835	COG1160	GTP binding
SAW_RS07855	COG0457	Tetratricopeptide repeat
SAW_RS07860	COG5582	Belongs to the UPF0302 family
SAW_RS07865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAW_RS07870	COG1694	Mazg nucleotide pyrophosphohydrolase
SAW_RS07875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SAW_RS07880	COG0617	tRNA 3'-terminal CCA addition
SAW_RS07895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SAW_RS07900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAW_RS07905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SAW_RS07910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SAW_RS07915	COG0287	Prephenate dehydrogenase
SAW_RS07920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SAW_RS07925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SAW_RS07930	COG0077	Prephenate dehydratase
SAW_RS07940	COG1307	EDD domain protein, DegV family
SAW_RS07965	COG0488	(ABC) transporter
SAW_RS07970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SAW_RS07980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAW_RS07985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SAW_RS07990	COG4224	UPF0291 protein
SAW_RS08000	COG2814	Major facilitator Superfamily
SAW_RS08005	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS08005	COG1388	LysM domain
SAW_RS08015	COG0735	belongs to the Fur family
SAW_RS08020	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAW_RS08025	COG2816	NAD+ diphosphatase activity
SAW_RS08040	COG2207	Transcriptional regulator
SAW_RS08045	COG1132	(ABC) transporter
SAW_RS08050	COG1132	(ABC) transporter
SAW_RS08070	COG0753	catalase activity
SAW_RS08075	COG0415	Belongs to the DNA photolyase family
SAW_RS08085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS08085	COG2190	(PTS) system
SAW_RS08085	COG1263	PTS System
SAW_RS08090	COG0366	Alpha amylase catalytic
SAW_RS08100	COG1609	Transcriptional regulator
SAW_RS08110	COG2723	6-phospho-beta-galactosidase activity
SAW_RS08115	COG1263	PTS System
SAW_RS08115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS08115	COG2190	(PTS) system
SAW_RS08125	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SAW_RS08135	COG1227	inorganic diphosphatase activity
SAW_RS08140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SAW_RS08145	COG1882	Formate acetyltransferase
SAW_RS08150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAW_RS08155	COG0187	DNA topoisomerase II activity
SAW_RS08160	COG1832	CoA-binding protein
SAW_RS08165	COG4766	ethanolamine catabolic process
SAW_RS08170	COG3192	ethanolamine utilization protein
SAW_RS08175	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SAW_RS08185	COG4869	propanediol catabolic process
SAW_RS08200	COG1012	belongs to the aldehyde dehydrogenase family
SAW_RS08200	COG1454	alcohol dehydrogenase
SAW_RS08215	COG4302	ethanolamine ammonia-lyase activity
SAW_RS08220	COG4303	Ethanolamine ammonia lyase large subunit
SAW_RS08250	COG2096	Adenosyltransferase
SAW_RS08260	COG1120	ATPase activity
SAW_RS08265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAW_RS08270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAW_RS08275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SAW_RS08285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SAW_RS08290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SAW_RS08295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SAW_RS08305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SAW_RS08310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAW_RS08315	COG1266	CAAX protease self-immunity
SAW_RS08320	COG0758	DNA mediated transformation
SAW_RS08325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SAW_RS08335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAW_RS08340	COG0583	DNA-binding transcription factor activity
SAW_RS08350	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAW_RS08355	COG0022	dehydrogenase e1 component
SAW_RS08360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAW_RS08370	COG3426	butyrate kinase activity
SAW_RS08375	COG0280	phosphate acetyltransferase
SAW_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS08405	COG0346	lactoylglutathione lyase activity
SAW_RS08415	COG0604	alcohol dehydrogenase
SAW_RS08420	COG0577	efflux transmembrane transporter activity
SAW_RS08425	COG1136	(ABC) transporter
SAW_RS08435	COG1131	(ABC) transporter
SAW_RS08450	COG0681	Belongs to the peptidase S26 family
SAW_RS08455	COG3409	Peptidoglycan-binding domain 1 protein
SAW_RS08455	COG0793	Belongs to the peptidase S41A family
SAW_RS08460	COG4479	Belongs to the UPF0346 family
SAW_RS08465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SAW_RS08470	COG4698	Protein conserved in bacteria
SAW_RS08475	COG2755	lipolytic protein G-D-S-L family
SAW_RS08480	COG1307	EDD domain protein, DegV family
SAW_RS08485	COG1272	protein, Hemolysin III
SAW_RS08495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAW_RS08500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAW_RS08500	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAW_RS08505	COG5416	Lipopolysaccharide assembly protein A domain
SAW_RS08510	COG0300	oxidoreductase activity
SAW_RS08515	COG1234	tRNA 3'-trailer cleavage
SAW_RS08525	COG1837	Belongs to the UPF0109 family
SAW_RS08530	COG0228	four-way junction DNA binding
SAW_RS08535	COG1214	PFAM Peptidase M22, glycoprotease
SAW_RS08535	COG0456	acetyltransferase
SAW_RS08540	COG0431	NADPH-dependent FMN reductase
SAW_RS08545	COG0789	Transcriptional regulator
SAW_RS08550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAW_RS08555	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SAW_RS08560	COG1683	Conserved Protein
SAW_RS08565	COG0745	RESPONSE REGULATOR receiver
SAW_RS08570	COG5002	protein histidine kinase activity
SAW_RS08580	COG0436	Aminotransferase
SAW_RS08585	COG0383	alpha-mannosidase activity
SAW_RS08605	COG0583	DNA-binding transcription factor activity
SAW_RS08620	COG0284	orotidine-5'-phosphate decarboxylase activity
SAW_RS08625	COG0167	dihydroorotate dehydrogenase activity
SAW_RS08630	COG0543	2 iron, 2 sulfur cluster binding
SAW_RS08635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SAW_RS08640	COG0505	Belongs to the CarA family
SAW_RS08645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAW_RS08650	COG0540	Belongs to the ATCase OTCase family
SAW_RS08655	COG2233	PERMEase
SAW_RS08665	COG0564	pseudouridine synthase activity
SAW_RS08670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SAW_RS08680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SAW_RS08685	COG1278	Cold shock
SAW_RS08695	COG0328	RNA-DNA hybrid ribonuclease activity
SAW_RS08700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAW_RS08705	COG0710	3-dehydroquinate dehydratase activity
SAW_RS08710	COG1132	(ABC) transporter
SAW_RS08715	COG1132	(ABC) transporter
SAW_RS08720	COG3763	UPF0154 protein
SAW_RS08730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SAW_RS08750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SAW_RS08760	COG1609	Transcriptional regulator
SAW_RS08765	COG0006	proline dipeptidase activity
SAW_RS08770	COG4980	gas vesicle protein
SAW_RS08780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAW_RS08785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SAW_RS08790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SAW_RS08795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SAW_RS08800	COG0322	excinuclease ABC activity
SAW_RS08805	COG1950	PFAM Membrane protein of
SAW_RS08815	COG3595	metallopeptidase activity
SAW_RS08820	COG0704	Plays a role in the regulation of phosphate uptake
SAW_RS08825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAW_RS08830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SAW_RS08835	COG0581	inorganic phosphate transmembrane transporter activity
SAW_RS08840	COG0573	inorganic phosphate transmembrane transporter activity
SAW_RS08850	COG2177	Part of the ABC transporter FtsEX involved in
SAW_RS08855	COG2884	Cell division ATP-binding protein ftsE
SAW_RS08865	COG0653	protein targeting
SAW_RS08885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAW_RS08895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS08905	COG1739	Uncharacterized protein family UPF0029
SAW_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS08935	COG0151	Belongs to the GarS family
SAW_RS08940	COG0138	bifunctional purine biosynthesis protein purh
SAW_RS08945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SAW_RS08950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SAW_RS08960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAW_RS08965	COG0047	phosphoribosylformylglycinamidine synthase activity
SAW_RS08970	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAW_RS08975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SAW_RS08980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SAW_RS08985	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAW_RS08995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAW_RS09000	COG4166	transmembrane transport
SAW_RS09010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAW_RS09015	COG4876	unkown
SAW_RS09030	COG0628	permease
SAW_RS09035	COG1470	cell adhesion involved in biofilm formation
SAW_RS09035	COG0366	Alpha amylase catalytic
SAW_RS09045	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS09050	COG3715	PTS system
SAW_RS09055	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS09055	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS09065	COG1105	Belongs to the carbohydrate kinase PfkB family
SAW_RS09070	COG3684	Belongs to the aldolase LacD family
SAW_RS09075	COG2222	sugar isomerase
SAW_RS09080	COG2188	Transcriptional regulator
SAW_RS09085	COG1442	glycosyl transferase family 8
SAW_RS09090	COG1442	glycosyl transferase family 8
SAW_RS09095	COG1368	sulfuric ester hydrolase activity
SAW_RS09105	COG0583	DNA-binding transcription factor activity
SAW_RS09120	COG3227	Zinc metalloprotease (Elastase)
SAW_RS09130	COG4512	PFAM Accessory gene regulator B
SAW_RS09140	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS09140	COG3942	CHAP domain
SAW_RS09155	COG1064	alcohol dehydrogenase
SAW_RS09165	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SAW_RS09170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAW_RS09175	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS09185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS09185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS09190	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAW_RS09200	COG0698	ribose 5-phosphate isomerase
SAW_RS09205	COG0698	ribose 5-phosphate isomerase
SAW_RS09220	COG3775	system Galactitol-specific IIC component
SAW_RS09225	COG1349	DNA-binding transcription factor activity
SAW_RS09240	COG0726	polysaccharide deacetylase
SAW_RS09260	COG4974	Belongs to the 'phage' integrase family
SAW_RS09285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS09300	COG3328	transposase activity
SAW_RS09330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SAW_RS09335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SAW_RS09340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SAW_RS09355	COG5002	protein histidine kinase activity
SAW_RS09385	COG1136	(ABC) transporter
SAW_RS09400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAW_RS09420	COG3328	transposase activity
SAW_RS09430	COG0741	lytic transglycosylase activity
SAW_RS09430	COG0791	NLP P60 protein
SAW_RS09480	COG2946	Replication initiation factor
SAW_RS09510	COG1674	ftsk spoiiie
SAW_RS09540	COG0335	large ribosomal subunit rRNA binding
SAW_RS09545	COG0336	Belongs to the RNA methyltransferase TrmD family
SAW_RS09550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SAW_RS09555	COG1914	H( )-stimulated, divalent metal cation uptake system
SAW_RS09565	COG0398	Pfam SNARE associated Golgi protein
SAW_RS09570	COG0584	glycerophosphoryl diester phosphodiesterase
SAW_RS09590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SAW_RS09600	COG4129	membrane
SAW_RS09610	COG1940	carbohydrate kinase activity
SAW_RS09615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SAW_RS09630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SAW_RS09635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SAW_RS09640	COG2706	6-phosphogluconolactonase activity
SAW_RS09650	COG3069	C4-dicarboxylate transmembrane transporter activity
SAW_RS09680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAW_RS09690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SAW_RS09735	COG2364	Membrane
SAW_RS09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAW_RS09750	COG2814	Major facilitator Superfamily
SAW_RS09760	COG1368	sulfuric ester hydrolase activity
SAW_RS09795	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS09800	COG3715	PTS system
SAW_RS09815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SAW_RS09815	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SAW_RS09825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SAW_RS09845	COG0149	triose-phosphate isomerase activity
SAW_RS09850	COG0126	phosphoglycerate kinase activity
SAW_RS09860	COG2390	Transcriptional regulator
SAW_RS09865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAW_RS09870	COG4475	Protein of unknown function (DUF436)
SAW_RS09875	COG4720	Psort location CytoplasmicMembrane, score
SAW_RS09880	COG0351	phosphomethylpyrimidine kinase
SAW_RS09885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SAW_RS09890	COG0124	histidyl-tRNA synthetase
SAW_RS09900	COG1490	D-aminoacyl-tRNA deacylase activity
SAW_RS09905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SAW_RS09910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAW_RS09915	COG2264	protein methyltransferase activity
SAW_RS09925	COG2094	Belongs to the DNA glycosylase MPG family
SAW_RS09930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAW_RS09955	COG0589	response to stress
SAW_RS09960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SAW_RS09965	COG0827	DNA restriction-modification system
SAW_RS09990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SAW_RS10005	COG1278	Cold shock
SAW_RS10010	COG3942	CHAP domain
SAW_RS10010	COG1388	LysM domain
SAW_RS10240	COG3646	Phage regulatory protein
SAW_RS10255	COG1396	sequence-specific DNA binding
SAW_RS10270	COG0582	viral genome integration into host DNA
SAW_RS10280	COG4537	Required for transformation and DNA binding
SAW_RS10290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAW_RS10295	COG0531	amino acid
SAW_RS10300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SAW_RS10305	COG0577	efflux transmembrane transporter activity
SAW_RS10310	COG1136	(ABC) transporter
SAW_RS10320	COG1674	ftsk spoiiie
SAW_RS10330	COG1252	NADH dehydrogenase
SAW_RS10345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAW_RS10350	COG4988	ABC transporter
SAW_RS10355	COG1294	oxidase, subunit
SAW_RS10360	COG1271	oxidase subunit
SAW_RS10375	COG3708	Transcriptional regulator
SAW_RS10375	COG2207	Transcriptional regulator
SAW_RS10395	COG1881	PFAM PEBP family protein
SAW_RS10410	COG0482	sulfurtransferase activity
SAW_RS10420	COG1104	cysteine desulfurase activity
SAW_RS10425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SAW_RS10430	COG1121	(ABC) transporter
SAW_RS10435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAW_RS10445	COG0488	(ABC) transporter
SAW_RS10455	COG1473	amidohydrolase
SAW_RS10465	COG2011	ABC-type metal ion transport system permease component
SAW_RS10470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAW_RS10730	COG3935	DnaD domain protein
SAW_RS10790	COG1396	sequence-specific DNA binding
SAW_RS10835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAW_RS10845	COG1122	ATPase activity
SAW_RS10850	COG4720	Psort location CytoplasmicMembrane, score
SAW_RS10855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAW_RS10865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAW_RS10880	COG0789	Transcriptional regulator
SAW_RS10885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAW_RS10890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SAW_RS10895	COG0584	glycerophosphoryl diester phosphodiesterase
SAW_RS10915	COG1215	transferase activity, transferring glycosyl groups
SAW_RS10920	COG3475	LICD family
SAW_RS10930	COG1216	Glycosyl transferase, family 2
SAW_RS10930	COG1442	glycosyl transferase family 8
SAW_RS10935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAW_RS10955	COG3475	LICD family
SAW_RS10965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAW_RS10980	COG0438	transferase activity, transferring glycosyl groups
SAW_RS10980	COG1216	Glycosyl transferase, family 2
SAW_RS10985	COG0438	transferase activity, transferring glycosyl groups
SAW_RS10985	COG1216	Glycosyl transferase, family 2
SAW_RS10990	COG1134	teichoic acid transport
SAW_RS10995	COG1682	transport, permease protein
SAW_RS11015	COG1215	transferase activity, transferring glycosyl groups
SAW_RS11020	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAW_RS11025	COG1088	dTDP-glucose 4,6-dehydratase activity
SAW_RS11035	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SAW_RS11055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAW_RS11060	COG1295	ribonuclease BN
SAW_RS11065	COG0024	Methionine aminopeptidase
SAW_RS11070	COG0716	FMN binding
SAW_RS11075	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
SAW_RS11080	COG1309	transcriptional regulator
SAW_RS11085	COG2309	aminopeptidase activity
SAW_RS11100	COG0590	tRNA wobble adenosine to inosine editing
SAW_RS11110	COG0384	phenazine biosynthesis protein PhzF
SAW_RS11120	COG2738	Putative neutral zinc metallopeptidase
SAW_RS11135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS11135	COG1263	PTS System
SAW_RS11140	COG0346	lactoylglutathione lyase activity
SAW_RS11160	COG4753	response regulator
SAW_RS11160	COG2207	Transcriptional regulator
SAW_RS11165	COG2972	Histidine kinase
SAW_RS11175	COG1653	transport
SAW_RS11180	COG0395	ABC-type sugar transport system, permease component
SAW_RS11185	COG1175	transmembrane transport
SAW_RS11210	COG1132	(ABC) transporter
SAW_RS11235	COG0395	ABC-type sugar transport system, permease component
SAW_RS11240	COG1175	transmembrane transport
SAW_RS11250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAW_RS11265	COG1609	Transcriptional regulator
SAW_RS11275	COG0582	viral genome integration into host DNA
SAW_RS11350	COG4974	Belongs to the 'phage' integrase family
SAW_RS11355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS11390	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SAW_RS11415	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS11420	COG3715	PTS system
SAW_RS11430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SAW_RS11435	COG2188	Transcriptional regulator
SAW_RS11460	COG0741	lytic transglycosylase activity
SAW_RS11460	COG0791	NLP P60 protein
SAW_RS11505	COG2946	Replication initiation factor
SAW_RS11515	COG0270	DNA (cytosine-5-)-methyltransferase activity
SAW_RS11530	COG1674	ftsk spoiiie
SAW_RS11575	COG0481	GTPase activity
SAW_RS11590	COG0542	response to heat
SAW_RS11605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAW_RS11610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SAW_RS11625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAW_RS11635	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS11655	COG0017	Asparaginyl-tRNA synthetase
SAW_RS11660	COG0436	Aminotransferase
SAW_RS11670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAW_RS11670	COG1199	ATP-dependent helicase activity
SAW_RS11685	COG0531	amino acid
SAW_RS11695	COG0442	prolyl-tRNA aminoacylation
SAW_RS11700	COG0750	zinc metalloprotease
SAW_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
SAW_RS11735	COG1192	Involved in chromosome partitioning
SAW_RS11750	COG0719	Fe-S assembly protein
SAW_RS11760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAW_RS11765	COG0719	Fe-S assembly protein
SAW_RS11775	COG0233	cytoplasmic translational termination
SAW_RS11780	COG0528	UMP kinase activity
SAW_RS11785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAW_RS11790	COG0052	Belongs to the universal ribosomal protein uS2 family
SAW_RS11800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAW_RS11805	COG1254	Belongs to the acylphosphatase family
SAW_RS11815	COG0706	membrane insertase activity
SAW_RS11825	COG0751	glycine-tRNA ligase activity
SAW_RS11830	COG0752	glycyl-tRNA synthetase alpha subunit
SAW_RS11840	COG1381	Involved in DNA repair and RecF pathway recombination
SAW_RS11845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SAW_RS11850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SAW_RS11855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAW_RS11865	COG1702	phosphate starvation-inducible protein PhoH
SAW_RS11870	COG1610	YqeY-like protein
SAW_RS11875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SAW_RS11880	COG0735	belongs to the Fur family
SAW_RS11885	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SAW_RS11890	COG0083	homoserine kinase activity
SAW_RS11900	COG0460	homoserine dehydrogenase
SAW_RS11905	COG0640	Transcriptional regulator
SAW_RS11910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAW_RS11915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAW_RS11920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAW_RS11935	COG0516	GMP reductase activity
SAW_RS11945	COG0402	S-adenosylhomocysteine deaminase activity
SAW_RS11960	COG1737	Transcriptional regulator
SAW_RS11965	COG1263	PTS System
SAW_RS11965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS11970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SAW_RS11980	COG1263	PTS System
SAW_RS11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS11980	COG2190	(PTS) system
SAW_RS11985	COG1968	undecaprenyl-diphosphatase activity
SAW_RS11990	COG3394	polysaccharide catabolic process
SAW_RS12000	COG0306	phosphate transporter
SAW_RS12010	COG0268	Binds directly to 16S ribosomal RNA
SAW_RS12015	COG1607	acyl-coa hydrolase
SAW_RS12020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAW_RS12025	COG1466	dna polymerase III delta subunit
SAW_RS12030	COG2333	competence protein COMEC
SAW_RS12030	COG0658	competence protein
SAW_RS12035	COG2131	deaminase
SAW_RS12040	COG1555	photosystem II stabilization
SAW_RS12045	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAW_RS12050	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SAW_RS12055	COG0742	ribosomal rna small subunit methyltransferase
SAW_RS12060	COG4471	UPF0298 protein
SAW_RS12075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SAW_RS12080	COG0772	Belongs to the SEDS family
SAW_RS12085	COG4838	Belongs to the UPF0358 family
SAW_RS12090	COG0514	ATP-dependent DNA helicase (RecQ)
SAW_RS12095	COG1217	gtp-binding protein TYPA
SAW_RS12100	COG0483	inositol monophosphate 1-phosphatase activity
SAW_RS12105	COG4476	Belongs to the UPF0223 family
SAW_RS12110	COG0038	chloride channel
SAW_RS12115	COG1215	transferase activity, transferring glycosyl groups
SAW_RS12145	COG0018	arginyl-trna synthetase
SAW_RS12150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SAW_RS12155	COG0456	acetyltransferase
SAW_RS12165	COG1214	PFAM Peptidase M22, glycoprotease
SAW_RS12195	COG0546	phosphoglycolate phosphatase activity
SAW_RS12210	COG1682	transport, permease protein
SAW_RS12215	COG1134	teichoic acid transport
SAW_RS12215	COG1388	LysM domain
SAW_RS12220	COG0562	UDP-galactopyranose mutase
SAW_RS12240	COG1216	Glycosyl transferase, family 2
SAW_RS12245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAW_RS12245	COG1215	transferase activity, transferring glycosyl groups
SAW_RS12250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAW_RS12255	COG4589	Belongs to the CDS family
SAW_RS12260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAW_RS12265	COG1464	Belongs to the NlpA lipoprotein family
SAW_RS12270	COG2011	ABC-type metal ion transport system permease component
SAW_RS12275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAW_RS12290	COG0509	glycine decarboxylation via glycine cleavage system
SAW_RS12295	COG1393	Belongs to the ArsC family
SAW_RS12300	COG0772	Belongs to the SEDS family
SAW_RS12325	COG1396	sequence-specific DNA binding
SAW_RS12360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAW_RS12365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SAW_RS12370	COG0009	L-threonylcarbamoyladenylate synthase
SAW_RS12375	COG2890	protein-(glutamine-N5) methyltransferase activity
SAW_RS12380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SAW_RS12385	COG1435	thymidine kinase activity
SAW_RS12390	COG1053	succinate dehydrogenase
SAW_RS12395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAW_RS12405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SAW_RS12405	COG0493	'glutamate synthase
SAW_RS12410	COG0543	2 iron, 2 sulfur cluster binding
SAW_RS12415	COG0716	FMN binding
SAW_RS12420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SAW_RS12420	COG3608	succinylglutamate desuccinylase aspartoacylase
SAW_RS12425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SAW_RS12445	COG1104	cysteine desulfurase activity
SAW_RS12450	COG0746	molybdenum cofactor guanylyltransferase activity
SAW_RS12460	COG3608	succinylglutamate desuccinylase aspartoacylase
SAW_RS12460	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SAW_RS12475	COG0251	oxidation-reduction process
SAW_RS12480	COG0549	Belongs to the carbamate kinase family
SAW_RS12490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAW_RS12495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAW_RS12510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SAW_RS12510	COG0493	'glutamate synthase
SAW_RS12515	COG0402	S-adenosylhomocysteine deaminase activity
SAW_RS12530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAW_RS12535	COG3442	glutamine amidotransferase
SAW_RS12540	COG1957	nucleoside hydrolase
SAW_RS12550	COG1482	cell wall glycoprotein biosynthetic process
SAW_RS12565	COG1132	(ABC) transporter
SAW_RS12580	COG0194	GDP metabolic process
SAW_RS12585	COG2723	6-phospho-beta-galactosidase activity
SAW_RS12590	COG1263	PTS System
SAW_RS12590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS12590	COG2190	(PTS) system
SAW_RS12595	COG3711	transcriptional antiterminator
SAW_RS12605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SAW_RS12610	COG0628	permease
SAW_RS12625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SAW_RS12630	COG4836	Membrane
SAW_RS12635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SAW_RS12640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SAW_RS12645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SAW_RS12650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SAW_RS12655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SAW_RS12660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SAW_RS12665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SAW_RS12670	COG0356	it plays a direct role in the translocation of protons across the membrane
SAW_RS12680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAW_RS12685	COG0557	exoribonuclease II activity
SAW_RS12700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAW_RS12705	COG2388	GCN5-related N-acetyl-transferase
SAW_RS12710	COG3592	Divergent 4Fe-4S mono-cluster
SAW_RS12715	COG2217	Heavy metal translocating P-type atpase
SAW_RS12725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SAW_RS12730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAW_RS12735	COG2246	polysaccharide biosynthetic process
SAW_RS12740	COG3942	CHAP domain
SAW_RS12740	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAW_RS12755	COG0459	protein refolding
SAW_RS12760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAW_RS12775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SAW_RS12780	COG0488	(ABC) transporter
SAW_RS12790	COG3448	diguanylate cyclase activity
SAW_RS12790	COG4175	Glycine betaine
SAW_RS12805	COG1597	lipid kinase activity
SAW_RS12810	COG3835	regulator
SAW_RS12815	COG1929	Belongs to the glycerate kinase type-1 family
SAW_RS12820	COG2610	gluconate transmembrane transporter activity
SAW_RS12825	COG0398	Pfam SNARE associated Golgi protein
SAW_RS12830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAW_RS12835	COG1177	transmembrane transport
SAW_RS12840	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAW_RS12845	COG3842	ATPase activity
SAW_RS12855	COG0604	alcohol dehydrogenase
SAW_RS12865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAW_RS12870	COG4684	Psort location CytoplasmicMembrane, score
SAW_RS12875	COG2348	transferase activity, transferring amino-acyl groups
SAW_RS12895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAW_RS12905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SAW_RS12920	COG3142	Participates in the control of copper homeostasis
SAW_RS12925	COG2239	Acts as a magnesium transporter
SAW_RS12930	COG0564	pseudouridine synthase activity
SAW_RS12935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SAW_RS12940	COG2357	RelA SpoT domain protein
SAW_RS12945	COG4116	CYTH
SAW_RS12955	COG1164	Oligoendopeptidase f
SAW_RS12965	COG4862	establishment of competence for transformation
SAW_RS12970	COG1393	Belongs to the ArsC family
SAW_RS12975	COG0180	Tryptophanyl-tRNA synthetase
SAW_RS12980	COG1132	(ABC) transporter
SAW_RS13025	COG0419	ATPase involved in DNA repair
SAW_RS13030	COG0420	3'-5' exonuclease activity
SAW_RS13035	COG0204	Acyl-transferase
SAW_RS13040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAW_RS13045	COG2827	Endonuclease containing a URI domain
SAW_RS13050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAW_RS13060	COG0494	nUDIX hydrolase
SAW_RS13070	COG3853	Toxic anion resistance protein (TelA)
SAW_RS13100	COG1194	a g-specific adenine glycosylase
SAW_RS13105	COG2137	regulation of response to DNA damage stimulus
SAW_RS13110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAW_RS13120	COG2261	transglycosylase associated protein
SAW_RS13125	COG3250	beta-galactosidase activity
SAW_RS13130	COG0531	amino acid
SAW_RS13135	COG2207	Transcriptional regulator
SAW_RS13135	COG1917	Cupin 2, conserved barrel domain protein
SAW_RS13150	COG0222	ribosome binding
SAW_RS13155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SAW_RS13160	COG0081	regulation of translation
SAW_RS13165	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SAW_RS13170	COG0488	(ABC) transporter
SAW_RS13175	COG1760	l-serine dehydratase
SAW_RS13180	COG1760	l-serine dehydratase
SAW_RS13190	COG1363	Peptidase, m42
SAW_RS13195	COG4166	transmembrane transport
SAW_RS13210	COG0250	Participates in transcription elongation, termination and antitermination
SAW_RS13215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAW_RS13220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAW_RS13230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAW_RS13240	COG0708	Exodeoxyribonuclease III
SAW_RS13275	COG0095	Lipoate-protein ligase
SAW_RS13280	COG1234	tRNA 3'-trailer cleavage
SAW_RS13290	COG1363	Peptidase, m42
SAW_RS13295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAW_RS13300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAW_RS13305	COG1696	Membrane protein involved in D-alanine export
SAW_RS13310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAW_RS13320	COG0577	efflux transmembrane transporter activity
SAW_RS13325	COG1136	(ABC) transporter
SAW_RS13330	COG1328	CTP reductase activity
SAW_RS13335	COG0602	queuosine metabolic process
SAW_RS13345	COG0390	transport system, permease component
SAW_RS13350	COG4619	ABC transporter
SAW_RS13360	COG4467	Involved in initiation control of chromosome replication
SAW_RS13365	COG1774	PSP1 C-terminal conserved region
SAW_RS13370	COG0470	DNA polymerase III
SAW_RS13375	COG3870	Protein conserved in bacteria
SAW_RS13380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SAW_RS13390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SAW_RS13395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAW_RS13405	COG1122	ATPase activity
SAW_RS13425	COG0477	Major facilitator Superfamily
SAW_RS13430	COG2814	Major facilitator Superfamily
SAW_RS13435	COG1733	regulation of RNA biosynthetic process
SAW_RS13440	COG0351	phosphomethylpyrimidine kinase
SAW_RS13445	COG0352	thiamine-phosphate diphosphorylase activity
SAW_RS13450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SAW_RS13460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAW_RS13465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAW_RS13470	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SAW_RS13475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAW_RS13490	COG3189	MarR family transcriptional regulator
SAW_RS13495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAW_RS13500	COG1940	carbohydrate kinase activity
SAW_RS13515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAW_RS13520	COG1073	alpha beta
SAW_RS13830	COG1396	sequence-specific DNA binding
SAW_RS13840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAW_RS13850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAW_RS13855	COG0768	penicillin binding
SAW_RS13860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SAW_RS13865	COG1942	4-Oxalocrotonate Tautomerase
SAW_RS13895	COG0217	transcriptional regulatory protein
SAW_RS13900	COG1323	Belongs to the UPF0348 family
SAW_RS13905	COG2226	methyltransferase
SAW_RS13910	COG0799	negative regulation of ribosome biogenesis
SAW_RS13915	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAW_RS13920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAW_RS13925	COG1534	Rna-binding protein
SAW_RS13930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAW_RS13940	COG0825	malonyl-CoA metabolic process
SAW_RS13945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SAW_RS13950	COG0439	Biotin carboxylase
SAW_RS13955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SAW_RS13965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAW_RS13975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SAW_RS13990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAW_RS13995	COG1846	Transcriptional regulator
SAW_RS14000	COG4703	Protein of unknown function (DUF1797)
SAW_RS14005	COG2084	Dehydrogenase
SAW_RS14010	COG0438	transferase activity, transferring glycosyl groups
SAW_RS14065	COG1098	S1 RNA binding domain
SAW_RS14070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SAW_RS14085	COG0492	ferredoxin-NADP+ reductase activity
SAW_RS14100	COG0737	Belongs to the 5'-nucleotidase family
SAW_RS14120	COG1175	transmembrane transport
SAW_RS14125	COG3842	ATPase activity
SAW_RS14130	COG0463	Glycosyl transferase, family 2
SAW_RS14135	COG4841	protein insertion into membrane
SAW_RS14140	COG0569	domain protein
SAW_RS14145	COG2197	response regulator
SAW_RS14150	COG4585	Histidine kinase
SAW_RS14160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SAW_RS14165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SAW_RS14175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAW_RS14180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SAW_RS14200	COG2832	Protein of unknown function (DUF454)
SAW_RS14205	COG5503	Protein of unknown function (DUF1447)
SAW_RS14215	COG1278	Cold shock
SAW_RS14220	COG2003	Belongs to the UPF0758 family
SAW_RS14225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAW_RS14230	COG0285	dihydrofolate synthase activity
SAW_RS14245	COG0525	valine-tRNA ligase activity
SAW_RS14250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SAW_RS14255	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SAW_RS14260	COG0301	tRNA thio-modification
SAW_RS14265	COG0582	viral genome integration into host DNA
SAW_RS14305	COG0433	COG0433 Predicted ATPase
SAW_RS14335	COG3764	Sortase (surface protein transpeptidase)
SAW_RS14355	COG2946	Replication initiation factor
SAW_RS14380	COG1674	ftsk spoiiie
SAW_RS14435	COG1396	sequence-specific DNA binding
SAW_RS14445	COG1733	regulation of RNA biosynthetic process
SAW_RS14450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAW_RS14455	COG0656	L-ascorbic acid biosynthetic process
SAW_RS14460	COG0789	Transcriptional regulator
SAW_RS14465	COG0588	phosphoglycerate mutase activity
SAW_RS14470	COG1733	regulation of RNA biosynthetic process
SAW_RS14530	COG0789	Transcriptional regulator
SAW_RS14570	COG2252	PERMEase
SAW_RS14680	COG1396	sequence-specific DNA binding
SAW_RS14690	COG4221	oxidoreductase activity
SAW_RS14695	COG0110	maltose O-acetyltransferase activity
SAW_RS14700	COG0583	DNA-binding transcription factor activity
SAW_RS14705	COG4975	Glucose uptake
SAW_RS14710	COG1869	D-ribose catabolic process
SAW_RS14720	COG1609	Transcriptional regulator
SAW_RS14725	COG0657	acetylesterase activity
SAW_RS14740	COG3711	transcriptional antiterminator
SAW_RS14770	COG1834	amidinotransferase
SAW_RS14775	COG1785	Belongs to the alkaline phosphatase family
SAW_RS14780	COG1193	negative regulation of DNA recombination
SAW_RS14795	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS14800	COG3715	PTS system
SAW_RS14805	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS14835	COG0577	efflux transmembrane transporter activity
SAW_RS14840	COG1136	(ABC) transporter
SAW_RS14845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SAW_RS14855	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAW_RS14865	COG1937	Protein conserved in bacteria
SAW_RS14875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAW_RS14880	COG2508	Transcriptional regulator
SAW_RS14885	COG3257	ureidoglycine aminohydrolase activity
SAW_RS14890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAW_RS14895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAW_RS14900	COG1953	Uracil, thiamine, allantoin
SAW_RS14910	COG1846	Transcriptional regulator
SAW_RS14920	COG0659	secondary active sulfate transmembrane transporter activity
SAW_RS14925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SAW_RS14940	COG2508	Transcriptional regulator
SAW_RS14950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SAW_RS14955	COG1304	FMN binding
SAW_RS14970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAW_RS14975	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SAW_RS14980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SAW_RS15010	COG1823	symporter activity
SAW_RS15015	COG5492	domain, Protein
SAW_RS15025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SAW_RS15030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAW_RS15035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAW_RS15040	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS15045	COG3715	PTS system
SAW_RS15050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS15065	COG2188	Transcriptional regulator
SAW_RS15075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAW_RS15080	COG1363	Peptidase, m42
SAW_RS15095	COG4166	transmembrane transport
SAW_RS15100	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS15105	COG3715	PTS system
SAW_RS15110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAW_RS15115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS15130	COG3394	polysaccharide catabolic process
SAW_RS15140	COG0519	Catalyzes the synthesis of GMP from XMP
SAW_RS15170	COG3764	Sortase (surface protein transpeptidase)
SAW_RS15180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAW_RS15210	COG1185	polyribonucleotide nucleotidyltransferase activity
SAW_RS15215	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SAW_RS15220	COG0242	peptide deformylase activity
SAW_RS15240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SAW_RS15250	COG1268	BioY protein
SAW_RS15285	COG4493	Belongs to the UPF0637 family
SAW_RS15295	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAW_RS15300	COG4166	transmembrane transport
SAW_RS15310	COG4607	ABC-type enterochelin transport system periplasmic component
SAW_RS15315	COG4604	ABC transporter, ATP-binding protein
SAW_RS15320	COG4605	iron ion homeostasis
SAW_RS15325	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAW_RS15345	COG2918	glutathione biosynthetic process
SAW_RS15345	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAW_RS15355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAW_RS15370	COG0552	protein localization to endoplasmic reticulum
SAW_RS15375	COG0561	phosphatase activity
SAW_RS15380	COG1196	nuclear chromosome segregation
SAW_RS15385	COG0571	ribonuclease III activity
SAW_RS15410	COG1120	ATPase activity
SAW_RS15430	COG0601	transmembrane transport
SAW_RS15435	COG4608	Belongs to the ABC transporter superfamily
SAW_RS15445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAW_RS15450	COG0416	fatty acid biosynthetic process
SAW_RS15455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAW_RS15460	COG1461	Dihydroxyacetone kinase
SAW_RS15470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SAW_RS15480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAW_RS15485	COG1162	GTPase activity
SAW_RS15490	COG2815	serine threonine protein kinase
SAW_RS15490	COG0515	serine threonine protein kinase
SAW_RS15500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAW_RS15500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAW_RS15505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAW_RS15515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAW_RS15520	COG1758	RNA polymerase activity
SAW_RS15525	COG0194	GDP metabolic process
SAW_RS15555	COG0800	Aldolase
SAW_RS15560	COG1312	Catalyzes the dehydration of D-mannonate
SAW_RS15570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAW_RS15575	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS15585	COG0371	Dehydrogenase
SAW_RS15595	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SAW_RS15605	COG1737	Transcriptional regulator
SAW_RS15620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAW_RS15625	COG1426	Protein conserved in bacteria
SAW_RS15630	COG0612	Peptidase, M16
SAW_RS15635	COG0612	Peptidase, M16
SAW_RS15640	COG1970	mechanosensitive ion channel activity
SAW_RS15665	COG1554	hydrolase, family 65, central catalytic
SAW_RS15670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAW_RS15690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SAW_RS15700	COG0424	maF-like protein
SAW_RS15705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SAW_RS15710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAW_RS15715	COG4550	Control of competence regulator ComK, YlbF/YmcA
SAW_RS15720	COG1692	metallophosphoesterase
SAW_RS15725	COG1418	mRNA catabolic process
SAW_RS15735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SAW_RS15740	COG1058	Belongs to the CinA family
SAW_RS15740	COG1546	Belongs to the CinA family
SAW_RS15745	COG2433	Pfam Transposase IS66
SAW_RS15750	COG2910	NAD(P)H-binding
SAW_RS15755	COG1959	2 iron, 2 sulfur cluster binding
SAW_RS15770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAW_RS15835	COG1335	isochorismatase
SAW_RS15840	COG1346	cytolysis
SAW_RS15850	COG3279	Response regulator of the LytR AlgR family
SAW_RS15855	COG3275	phosphorelay sensor kinase activity
SAW_RS15865	COG2011	ABC-type metal ion transport system permease component
SAW_RS15880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SAW_RS15885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAW_RS15900	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAW_RS15900	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAW_RS15910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SAW_RS15915	COG0842	Transport permease protein
SAW_RS15920	COG1131	(ABC) transporter
SAW_RS15935	COG3715	PTS system
SAW_RS15940	COG3716	PTS system mannose fructose sorbose family IID component
SAW_RS15955	COG0494	nUDIX hydrolase
SAW_RS16010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SAW_RS16015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAW_RS16025	COG0783	Belongs to the Dps family
SAW_RS16035	COG1070	Carbohydrate kinase
SAW_RS16040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAW_RS16045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SAW_RS16050	COG0085	RNA polymerase activity
SAW_RS16090	COG1316	TRANSCRIPTIONal
SAW_RS16130	COG1575	Belongs to the MenA family. Type 1 subfamily
SAW_RS16140	COG4939	FMN-binding domain protein
SAW_RS16160	COG0142	geranyltranstransferase activity
SAW_RS16180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SAW_RS16185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SAW_RS16190	COG0302	gtp cyclohydrolase
SAW_RS16200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SAW_RS16205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAW_RS16245	COG2508	Transcriptional regulator
SAW_RS16245	COG2508	Transcriptional regulator
SAW_RS16250	COG0826	peptidase U32
SAW_RS16255	COG0826	peptidase U32
SAW_RS16275	COG0542	response to heat
SAW_RS16280	COG4463	regulation of RNA biosynthetic process
SAW_RS16285	COG0626	cystathionine gamma-synthase activity
SAW_RS16290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SAW_RS16295	COG1737	Transcriptional regulator
SAW_RS16375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAW_RS16380	COG0516	GMP reductase activity
SAW_RS16380	COG0517	IMP dehydrogenase activity
SAW_RS16395	COG0012	GTP binding
SAW_RS16400	COG4481	Protein conserved in bacteria
SAW_RS16405	COG1475	DNA binding
SAW_RS16410	COG1192	Involved in chromosome partitioning
SAW_RS16415	COG0357	Ribosomal RNA small subunit methyltransferase G
SAW_RS16455	COG3732	PTS system glucitol sorbitol-specific
SAW_RS16460	COG3730	PTS system glucitol sorbitol-specific
SAW_RS16480	COG0445	tRNA wobble uridine modification
SAW_RS16485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SAW_RS16500	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SAW_RS16515	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SAW_RS16515	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
SAW_RS16530	COG3052	prosthetic group binding
SAW_RS16535	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SAW_RS16545	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SAW_RS16550	COG0511	ligase activity, forming carbon-carbon bonds
SAW_RS16560	COG2851	Citrate transporter
SAW_RS16570	COG0745	RESPONSE REGULATOR receiver
SAW_RS16580	COG0706	membrane insertase activity
SAW_RS16585	COG0594	ribonuclease P activity
SAW_RS16590	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SAW_RS16605	COG1388	LysM domain
SAW_RS16605	COG3942	CHAP domain
SAW_RS16645	COG0629	single-stranded DNA binding
SAW_RS16680	COG3843	relaxase mobilization nuclease domain protein
SAW_RS16745	COG0629	single-stranded DNA binding
SAW_RS16785	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAW_RS16785	COG1388	LysM domain
SAW_RS16805	COG3409	Peptidoglycan-binding domain 1 protein
SAW_RS16850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAW_RS16875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAW_RS16895	COG3328	transposase activity
SAW_RS16915	COG1192	Involved in chromosome partitioning
SAW_RS16935	COG4166	transmembrane transport
SAW_RS17060	COG0551	DNA topoisomerase type I activity
SAW_RS17060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAW_RS17080	COG0629	single-stranded DNA binding
SAW_RS17095	COG0456	acetyltransferase
SAW_RS17235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SAW_RS17270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs