locus-tag	class	description
H9Q64_RS00075	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS00075	COG3942	CHAP domain
H9Q64_RS00115	COG0629	single-stranded DNA binding
H9Q64_RS00170	COG0629	single-stranded DNA binding
H9Q64_RS00230	COG1609	Transcriptional regulator
H9Q64_RS00235	COG1621	beta-fructofuranosidase activity
H9Q64_RS00240	COG1263	PTS System
H9Q64_RS00240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS00240	COG2190	(PTS) system
H9Q64_RS00305	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS00305	COG3942	CHAP domain
H9Q64_RS00335	COG3328	transposase activity
H9Q64_RS00345	COG3041	Addiction module toxin RelE StbE family
H9Q64_RS00380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS00400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS00435	COG2226	methyltransferase
H9Q64_RS00505	COG1192	Involved in chromosome partitioning
H9Q64_RS00520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9Q64_RS00560	COG0629	single-stranded DNA binding
H9Q64_RS00565	COG1525	nuclease
H9Q64_RS00575	COG3041	Addiction module toxin RelE StbE family
H9Q64_RS00650	COG2207	Transcriptional regulator
H9Q64_RS00650	COG3708	Transcriptional regulator
H9Q64_RS00675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9Q64_RS00745	COG0456	acetyltransferase
H9Q64_RS00825	COG1192	Involved in chromosome partitioning
H9Q64_RS00870	COG1192	Involved in chromosome partitioning
H9Q64_RS00925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q64_RS00930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS00995	COG0741	lytic transglycosylase activity
H9Q64_RS00995	COG0791	NLP P60 protein
H9Q64_RS01045	COG0484	heat shock protein binding
H9Q64_RS01120	COG3942	CHAP domain
H9Q64_RS01120	COG1388	LysM domain
H9Q64_RS01125	COG1278	Cold shock
H9Q64_RS01140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9Q64_RS01160	COG0827	DNA restriction-modification system
H9Q64_RS01165	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9Q64_RS01170	COG0589	response to stress
H9Q64_RS01185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9Q64_RS01190	COG2094	Belongs to the DNA glycosylase MPG family
H9Q64_RS01200	COG2264	protein methyltransferase activity
H9Q64_RS01205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9Q64_RS01210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9Q64_RS01215	COG1490	D-aminoacyl-tRNA deacylase activity
H9Q64_RS01220	COG0124	histidyl-tRNA synthetase
H9Q64_RS01225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9Q64_RS01230	COG0351	phosphomethylpyrimidine kinase
H9Q64_RS01235	COG4720	Psort location CytoplasmicMembrane, score
H9Q64_RS01240	COG4475	Protein of unknown function (DUF436)
H9Q64_RS01245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q64_RS01250	COG2390	Transcriptional regulator
H9Q64_RS01260	COG0126	phosphoglycerate kinase activity
H9Q64_RS01265	COG0149	triose-phosphate isomerase activity
H9Q64_RS01280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9Q64_RS01285	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9Q64_RS01285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9Q64_RS01300	COG3715	PTS system
H9Q64_RS01305	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS01335	COG1368	sulfuric ester hydrolase activity
H9Q64_RS01340	COG2814	Major facilitator Superfamily
H9Q64_RS01350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9Q64_RS01355	COG2364	Membrane
H9Q64_RS01395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q64_RS01405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9Q64_RS01435	COG3069	C4-dicarboxylate transmembrane transporter activity
H9Q64_RS01445	COG2706	6-phosphogluconolactonase activity
H9Q64_RS01450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9Q64_RS01455	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9Q64_RS01465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9Q64_RS01470	COG1940	carbohydrate kinase activity
H9Q64_RS01480	COG4129	membrane
H9Q64_RS01490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9Q64_RS01505	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q64_RS01510	COG0398	Pfam SNARE associated Golgi protein
H9Q64_RS01520	COG1914	H( )-stimulated, divalent metal cation uptake system
H9Q64_RS01525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9Q64_RS01530	COG0336	Belongs to the RNA methyltransferase TrmD family
H9Q64_RS01535	COG0335	large ribosomal subunit rRNA binding
H9Q64_RS01565	COG1674	ftsk spoiiie
H9Q64_RS01590	COG2946	Replication initiation factor
H9Q64_RS01640	COG0741	lytic transglycosylase activity
H9Q64_RS01640	COG0791	NLP P60 protein
H9Q64_RS01650	COG3328	transposase activity
H9Q64_RS01670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9Q64_RS01695	COG1136	(ABC) transporter
H9Q64_RS01715	COG5002	protein histidine kinase activity
H9Q64_RS01730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9Q64_RS01740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9Q64_RS01765	COG3328	transposase activity
H9Q64_RS01780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS01805	COG4974	Belongs to the 'phage' integrase family
H9Q64_RS01815	COG0726	polysaccharide deacetylase
H9Q64_RS01830	COG1349	DNA-binding transcription factor activity
H9Q64_RS01835	COG3775	system Galactitol-specific IIC component
H9Q64_RS01850	COG0698	ribose 5-phosphate isomerase
H9Q64_RS01855	COG0698	ribose 5-phosphate isomerase
H9Q64_RS01865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS01870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS01870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS01880	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS01885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9Q64_RS01890	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
H9Q64_RS01900	COG1064	alcohol dehydrogenase
H9Q64_RS01915	COG3942	CHAP domain
H9Q64_RS01915	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS01925	COG4512	PFAM Accessory gene regulator B
H9Q64_RS01935	COG3227	Zinc metalloprotease (Elastase)
H9Q64_RS01950	COG0583	DNA-binding transcription factor activity
H9Q64_RS01960	COG1368	sulfuric ester hydrolase activity
H9Q64_RS01965	COG1442	glycosyl transferase family 8
H9Q64_RS01970	COG1442	glycosyl transferase family 8
H9Q64_RS01975	COG2188	Transcriptional regulator
H9Q64_RS01980	COG2222	sugar isomerase
H9Q64_RS01985	COG3684	Belongs to the aldolase LacD family
H9Q64_RS01990	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q64_RS02000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS02000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS02005	COG3715	PTS system
H9Q64_RS02010	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS02020	COG1470	cell adhesion involved in biofilm formation
H9Q64_RS02020	COG0366	Alpha amylase catalytic
H9Q64_RS02025	COG0628	permease
H9Q64_RS02040	COG4876	unkown
H9Q64_RS02045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9Q64_RS02055	COG4166	transmembrane transport
H9Q64_RS02060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9Q64_RS02070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9Q64_RS02075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9Q64_RS02080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9Q64_RS02085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9Q64_RS02090	COG0047	phosphoribosylformylglycinamidine synthase activity
H9Q64_RS02095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9Q64_RS02105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9Q64_RS02110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9Q64_RS02115	COG0138	bifunctional purine biosynthesis protein purh
H9Q64_RS02120	COG0151	Belongs to the GarS family
H9Q64_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS02150	COG1739	Uncharacterized protein family UPF0029
H9Q64_RS02160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS02170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H9Q64_RS02185	COG0653	protein targeting
H9Q64_RS02195	COG2884	Cell division ATP-binding protein ftsE
H9Q64_RS02200	COG2177	Part of the ABC transporter FtsEX involved in
H9Q64_RS02210	COG0573	inorganic phosphate transmembrane transporter activity
H9Q64_RS02215	COG0581	inorganic phosphate transmembrane transporter activity
H9Q64_RS02220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q64_RS02225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q64_RS02230	COG0704	Plays a role in the regulation of phosphate uptake
H9Q64_RS02235	COG3595	metallopeptidase activity
H9Q64_RS02245	COG1950	PFAM Membrane protein of
H9Q64_RS02250	COG0322	excinuclease ABC activity
H9Q64_RS02255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9Q64_RS02260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9Q64_RS02265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9Q64_RS02270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9Q64_RS02280	COG4980	gas vesicle protein
H9Q64_RS02285	COG0006	proline dipeptidase activity
H9Q64_RS02290	COG1609	Transcriptional regulator
H9Q64_RS02300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9Q64_RS02315	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9Q64_RS02320	COG3763	UPF0154 protein
H9Q64_RS02325	COG1132	(ABC) transporter
H9Q64_RS02330	COG1132	(ABC) transporter
H9Q64_RS02335	COG0710	3-dehydroquinate dehydratase activity
H9Q64_RS02340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9Q64_RS02345	COG0328	RNA-DNA hybrid ribonuclease activity
H9Q64_RS02355	COG1278	Cold shock
H9Q64_RS02360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9Q64_RS02370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9Q64_RS02375	COG0564	pseudouridine synthase activity
H9Q64_RS02385	COG2233	PERMEase
H9Q64_RS02390	COG0540	Belongs to the ATCase OTCase family
H9Q64_RS02395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9Q64_RS02400	COG0505	Belongs to the CarA family
H9Q64_RS02405	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9Q64_RS02410	COG0543	2 iron, 2 sulfur cluster binding
H9Q64_RS02415	COG0167	dihydroorotate dehydrogenase activity
H9Q64_RS02420	COG0284	orotidine-5'-phosphate decarboxylase activity
H9Q64_RS02435	COG0583	DNA-binding transcription factor activity
H9Q64_RS02450	COG0383	alpha-mannosidase activity
H9Q64_RS02455	COG0436	Aminotransferase
H9Q64_RS02465	COG5002	protein histidine kinase activity
H9Q64_RS02470	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS02475	COG1683	Conserved Protein
H9Q64_RS02480	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H9Q64_RS02485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9Q64_RS02490	COG0789	Transcriptional regulator
H9Q64_RS02495	COG0431	NADPH-dependent FMN reductase
H9Q64_RS02500	COG1214	PFAM Peptidase M22, glycoprotease
H9Q64_RS02500	COG0456	acetyltransferase
H9Q64_RS02505	COG0228	four-way junction DNA binding
H9Q64_RS02510	COG1837	Belongs to the UPF0109 family
H9Q64_RS02520	COG1234	tRNA 3'-trailer cleavage
H9Q64_RS02525	COG0300	oxidoreductase activity
H9Q64_RS02530	COG5416	Lipopolysaccharide assembly protein A domain
H9Q64_RS02535	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9Q64_RS02535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9Q64_RS02540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q64_RS02550	COG1272	protein, Hemolysin III
H9Q64_RS02555	COG1307	EDD domain protein, DegV family
H9Q64_RS02560	COG2755	lipolytic protein G-D-S-L family
H9Q64_RS02565	COG4698	Protein conserved in bacteria
H9Q64_RS02570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9Q64_RS02575	COG4479	Belongs to the UPF0346 family
H9Q64_RS02580	COG0793	Belongs to the peptidase S41A family
H9Q64_RS02580	COG3409	Peptidoglycan-binding domain 1 protein
H9Q64_RS02585	COG0681	Belongs to the peptidase S26 family
H9Q64_RS02600	COG1131	(ABC) transporter
H9Q64_RS02610	COG1136	(ABC) transporter
H9Q64_RS02615	COG0577	efflux transmembrane transporter activity
H9Q64_RS02620	COG0604	alcohol dehydrogenase
H9Q64_RS02630	COG0346	lactoylglutathione lyase activity
H9Q64_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS02660	COG0280	phosphate acetyltransferase
H9Q64_RS02665	COG3426	butyrate kinase activity
H9Q64_RS02670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9Q64_RS02675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9Q64_RS02680	COG0022	dehydrogenase e1 component
H9Q64_RS02685	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9Q64_RS02695	COG0583	DNA-binding transcription factor activity
H9Q64_RS02700	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9Q64_RS02710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q64_RS02715	COG0758	DNA mediated transformation
H9Q64_RS02720	COG1266	CAAX protease self-immunity
H9Q64_RS02725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q64_RS02730	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H9Q64_RS02740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9Q64_RS02745	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9Q64_RS02750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H9Q64_RS02760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9Q64_RS02765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9Q64_RS02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q64_RS02775	COG1120	ATPase activity
H9Q64_RS02785	COG2096	Adenosyltransferase
H9Q64_RS02815	COG4303	Ethanolamine ammonia lyase large subunit
H9Q64_RS02820	COG4302	ethanolamine ammonia-lyase activity
H9Q64_RS02835	COG1012	belongs to the aldehyde dehydrogenase family
H9Q64_RS02835	COG1454	alcohol dehydrogenase
H9Q64_RS02850	COG4869	propanediol catabolic process
H9Q64_RS02860	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
H9Q64_RS02865	COG3192	ethanolamine utilization protein
H9Q64_RS02870	COG4766	ethanolamine catabolic process
H9Q64_RS02875	COG1832	CoA-binding protein
H9Q64_RS02880	COG0187	DNA topoisomerase II activity
H9Q64_RS02885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9Q64_RS02890	COG1882	Formate acetyltransferase
H9Q64_RS02895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9Q64_RS02900	COG1227	inorganic diphosphatase activity
H9Q64_RS02910	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H9Q64_RS02920	COG2190	(PTS) system
H9Q64_RS02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS02920	COG1263	PTS System
H9Q64_RS02925	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS02935	COG1609	Transcriptional regulator
H9Q64_RS02945	COG0366	Alpha amylase catalytic
H9Q64_RS02950	COG1263	PTS System
H9Q64_RS02950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS02950	COG2190	(PTS) system
H9Q64_RS02960	COG0415	Belongs to the DNA photolyase family
H9Q64_RS02965	COG0753	catalase activity
H9Q64_RS02980	COG1132	(ABC) transporter
H9Q64_RS02985	COG1132	(ABC) transporter
H9Q64_RS02990	COG2207	Transcriptional regulator
H9Q64_RS03005	COG2816	NAD+ diphosphatase activity
H9Q64_RS03010	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q64_RS03015	COG0735	belongs to the Fur family
H9Q64_RS03025	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS03025	COG1388	LysM domain
H9Q64_RS03030	COG2814	Major facilitator Superfamily
H9Q64_RS03040	COG4224	UPF0291 protein
H9Q64_RS03045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9Q64_RS03050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9Q64_RS03060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9Q64_RS03065	COG0488	(ABC) transporter
H9Q64_RS03090	COG1307	EDD domain protein, DegV family
H9Q64_RS03100	COG0077	Prephenate dehydratase
H9Q64_RS03105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9Q64_RS03110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9Q64_RS03115	COG0287	Prephenate dehydrogenase
H9Q64_RS03120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9Q64_RS03125	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9Q64_RS03130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9Q64_RS03135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q64_RS03150	COG0617	tRNA 3'-terminal CCA addition
H9Q64_RS03155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9Q64_RS03160	COG1694	Mazg nucleotide pyrophosphohydrolase
H9Q64_RS03165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q64_RS03170	COG5582	Belongs to the UPF0302 family
H9Q64_RS03175	COG0457	Tetratricopeptide repeat
H9Q64_RS03190	COG1160	GTP binding
H9Q64_RS03195	COG0539	negative regulation of cytoplasmic translation
H9Q64_RS03200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9Q64_RS03210	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q64_RS03230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9Q64_RS03235	COG1187	pseudouridine synthase activity
H9Q64_RS03240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9Q64_RS03245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H9Q64_RS03250	COG4974	Belongs to the 'phage' integrase family
H9Q64_RS03265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9Q64_RS03270	COG5294	Protein conserved in bacteria
H9Q64_RS03280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS03290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9Q64_RS03305	COG2996	Protein conserved in bacteria
H9Q64_RS03315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q64_RS03320	COG0358	DNA primase activity
H9Q64_RS03325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q64_RS03330	COG0741	lytic transglycosylase activity
H9Q64_RS03340	COG3711	transcriptional antiterminator
H9Q64_RS03345	COG4166	transmembrane transport
H9Q64_RS03355	COG4948	Mandelate Racemase Muconate Lactonizing
H9Q64_RS03360	COG2151	metal-sulfur cluster biosynthetic enzyme
H9Q64_RS03385	COG0019	diaminopimelate decarboxylase activity
H9Q64_RS03390	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
H9Q64_RS03405	COG1394	ATPase activity, coupled to movement of substances
H9Q64_RS03410	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
H9Q64_RS03415	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
H9Q64_RS03420	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
H9Q64_RS03425	COG1527	subunit (C
H9Q64_RS03430	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
H9Q64_RS03435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9Q64_RS03440	COG1269	ATP hydrolysis coupled proton transport
H9Q64_RS03460	COG0166	Belongs to the GPI family
H9Q64_RS03465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9Q64_RS03470	COG2081	HI0933 family
H9Q64_RS03475	COG0488	(ABC) transporter
H9Q64_RS03485	COG1486	melibiose metabolic process
H9Q64_RS03490	COG1609	Transcriptional regulator
H9Q64_RS03495	COG1668	transmembrane transport
H9Q64_RS03500	COG4152	abc transporter atp-binding protein
H9Q64_RS03510	COG0322	excinuclease ABC activity
H9Q64_RS03515	COG3118	belongs to the thioredoxin family
H9Q64_RS03520	COG1193	negative regulation of DNA recombination
H9Q64_RS03525	COG1286	toxin biosynthetic process
H9Q64_RS03535	COG2217	Heavy metal translocating P-type atpase
H9Q64_RS03540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9Q64_RS03545	COG4149	molybdate abc transporter
H9Q64_RS03550	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9Q64_RS03560	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9Q64_RS03575	COG0315	cyclic pyranopterin monophosphate synthase activity
H9Q64_RS03580	COG0303	'Molybdopterin
H9Q64_RS03585	COG3383	formate dehydrogenase (NAD+) activity
H9Q64_RS03590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H9Q64_RS03605	COG2116	formate transmembrane transporter activity
H9Q64_RS03610	COG0746	molybdenum cofactor guanylyltransferase activity
H9Q64_RS03625	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q64_RS03630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9Q64_RS03635	COG2384	SAM-dependent methyltransferase
H9Q64_RS03640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q64_RS03650	COG0513	Belongs to the DEAD box helicase family
H9Q64_RS03665	COG2824	Alkylphosphonate utilization operon protein PhnA
H9Q64_RS03670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9Q64_RS03675	COG4109	DRTGG domain
H9Q64_RS03680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9Q64_RS03685	COG2814	Major facilitator Superfamily
H9Q64_RS03700	COG1278	Cold shock
H9Q64_RS03710	COG0628	permease
H9Q64_RS03720	COG3425	synthase
H9Q64_RS03730	COG1461	Dihydroxyacetone kinase
H9Q64_RS03735	COG2376	Dihydroxyacetone kinase
H9Q64_RS03745	COG0371	Dehydrogenase
H9Q64_RS03780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q64_RS03790	COG0366	Alpha amylase catalytic
H9Q64_RS03795	COG0366	Alpha amylase catalytic
H9Q64_RS03800	COG0366	Alpha amylase catalytic
H9Q64_RS03805	COG2182	Extracellular solute-binding protein
H9Q64_RS03810	COG1175	transmembrane transport
H9Q64_RS03815	COG3833	ABC-type maltose transport systems, permease component
H9Q64_RS03825	COG0577	efflux transmembrane transporter activity
H9Q64_RS03825	COG0577	efflux transmembrane transporter activity
H9Q64_RS03825	COG1136	(ABC) transporter
H9Q64_RS03825	COG1136	(ABC) transporter
H9Q64_RS03840	COG0492	ferredoxin-NADP+ reductase activity
H9Q64_RS03850	COG3279	Response regulator of the LytR AlgR family
H9Q64_RS03860	COG3290	protein histidine kinase activity
H9Q64_RS03865	COG1131	(ABC) transporter
H9Q64_RS03885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9Q64_RS03890	COG2188	Transcriptional regulator
H9Q64_RS03900	COG1309	transcriptional regulator
H9Q64_RS03925	COG2268	Band 7 protein
H9Q64_RS03970	COG0436	Aminotransferase
H9Q64_RS03980	COG3091	SprT-like family
H9Q64_RS03985	COG2183	response to ionizing radiation
H9Q64_RS03995	COG0484	heat shock protein binding
H9Q64_RS04000	COG0443	Heat shock 70 kDa protein
H9Q64_RS04005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9Q64_RS04010	COG1420	regulation of RNA biosynthetic process
H9Q64_RS04015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q64_RS04020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q64_RS04025	COG0583	DNA-binding transcription factor activity
H9Q64_RS04030	COG0583	DNA-binding transcription factor activity
H9Q64_RS04035	COG0772	Belongs to the SEDS family
H9Q64_RS04055	COG1695	Transcriptional regulator
H9Q64_RS04065	COG0196	riboflavin kinase activity
H9Q64_RS04070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9Q64_RS04080	COG4824	toxin secretion phage lysis holin
H9Q64_RS04160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9Q64_RS04165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9Q64_RS04175	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H9Q64_RS04180	COG0195	Participates in both transcription termination and antitermination
H9Q64_RS04185	COG0779	Required for maturation of 30S ribosomal subunits
H9Q64_RS04190	COG4932	domain protein
H9Q64_RS04190	COG1388	LysM domain
H9Q64_RS04195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q64_RS04200	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q64_RS04205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9Q64_RS04210	COG1368	sulfuric ester hydrolase activity
H9Q64_RS04225	COG3850	Histidine kinase
H9Q64_RS04225	COG5002	protein histidine kinase activity
H9Q64_RS04230	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS04235	COG0561	phosphatase activity
H9Q64_RS04255	COG1122	ATPase activity
H9Q64_RS04275	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H9Q64_RS04290	COG2707	UPF0756 membrane protein
H9Q64_RS04295	COG0673	inositol 2-dehydrogenase activity
H9Q64_RS04300	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS04305	COG2188	Transcriptional regulator
H9Q64_RS04315	COG1609	Transcriptional regulator
H9Q64_RS04320	COG3459	Glycosyltransferase 36 associated
H9Q64_RS04325	COG1472	Belongs to the glycosyl hydrolase 3 family
H9Q64_RS04335	COG3458	cephalosporin-C deacetylase activity
H9Q64_RS04350	COG0395	ABC-type sugar transport system, permease component
H9Q64_RS04355	COG4209	transmembrane transport
H9Q64_RS04360	COG1408	metallophosphoesterase
H9Q64_RS04375	COG3976	FMN-binding domain protein
H9Q64_RS04375	COG1053	succinate dehydrogenase
H9Q64_RS04375	COG0431	NADPH-dependent FMN reductase
H9Q64_RS04395	COG0402	S-adenosylhomocysteine deaminase activity
H9Q64_RS04400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H9Q64_RS04410	COG3842	ATPase activity
H9Q64_RS04420	COG1175	transmembrane transport
H9Q64_RS04440	COG3527	Alpha-acetolactate decarboxylase
H9Q64_RS04445	COG0028	Belongs to the TPP enzyme family
H9Q64_RS04450	COG1316	TRANSCRIPTIONal
H9Q64_RS04460	COG1131	(ABC) transporter
H9Q64_RS04490	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q64_RS04495	COG4565	transcriptional regulatory protein
H9Q64_RS04500	COG3290	protein histidine kinase activity
H9Q64_RS04505	COG3493	citrate carrier protein
H9Q64_RS04520	COG3906	Belongs to the UPF0473 family
H9Q64_RS04525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9Q64_RS04530	COG4472	Bacterial protein of unknown function (DUF965)
H9Q64_RS04545	COG3689	TIGRFAM TIGR03943 family protein
H9Q64_RS04550	COG0701	Predicted permease
H9Q64_RS04555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9Q64_RS04570	COG5002	protein histidine kinase activity
H9Q64_RS04575	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS04580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9Q64_RS04585	COG1307	EDD domain protein, DegV family
H9Q64_RS04600	COG0647	UMP catabolic process
H9Q64_RS04605	COG4470	Protein conserved in bacteria
H9Q64_RS04610	COG0737	Belongs to the 5'-nucleotidase family
H9Q64_RS04620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q64_RS04625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9Q64_RS04630	COG1854	S-ribosylhomocysteine lyase activity
H9Q64_RS04635	COG0778	Nitroreductase
H9Q64_RS04640	COG3237	CsbD-like
H9Q64_RS04645	COG1940	carbohydrate kinase activity
H9Q64_RS04660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9Q64_RS04670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H9Q64_RS04680	COG0254	rRNA binding
H9Q64_RS04685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9Q64_RS04690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9Q64_RS04695	COG0191	fructose-bisphosphate aldolase activity
H9Q64_RS04700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q64_RS04705	COG1666	GTP binding
H9Q64_RS04730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS04735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS04740	COG1446	asparaginase
H9Q64_RS04750	COG2188	Transcriptional regulator
H9Q64_RS04755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9Q64_RS04760	COG3935	DnaD domain protein
H9Q64_RS04765	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9Q64_RS04770	COG0116	Belongs to the methyltransferase superfamily
H9Q64_RS04780	COG3599	regulation of cell shape
H9Q64_RS04785	COG4474	Belongs to the UPF0398 family
H9Q64_RS04790	COG3331	DNA recombination
H9Q64_RS04795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q64_RS04800	COG0504	CTP synthase activity
H9Q64_RS04815	COG0095	Lipoate-protein ligase
H9Q64_RS04820	COG1078	dGTPase activity
H9Q64_RS04840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9Q64_RS04845	COG0656	L-ascorbic acid biosynthetic process
H9Q64_RS04855	COG0668	transmembrane transport
H9Q64_RS04860	COG1473	amidohydrolase
H9Q64_RS04865	COG2171	N-acyltransferase activity
H9Q64_RS04870	COG0517	IMP dehydrogenase activity
H9Q64_RS04880	COG3623	hexulose-6-phosphate isomerase
H9Q64_RS04885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H9Q64_RS04895	COG3037	sugar-specific permease SgaT UlaA
H9Q64_RS04900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS04910	COG1349	DNA-binding transcription factor activity
H9Q64_RS04915	COG0622	Phosphoesterase
H9Q64_RS04920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9Q64_RS04925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9Q64_RS04935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q64_RS04940	COG0765	amino acid transport
H9Q64_RS04945	COG0765	amino acid transport
H9Q64_RS04950	COG0072	phenylalanine-tRNA ligase activity
H9Q64_RS04950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q64_RS04955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9Q64_RS04960	COG1733	regulation of RNA biosynthetic process
H9Q64_RS04965	COG1074	ATP-dependent DNA helicase activity
H9Q64_RS04970	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H9Q64_RS04985	COG1139	Iron-sulfur cluster binding protein
H9Q64_RS04990	COG0247	lactate metabolic process
H9Q64_RS05005	COG1113	amino acid transport
H9Q64_RS05020	COG1132	(ABC) transporter
H9Q64_RS05090	COG0456	acetyltransferase
H9Q64_RS05120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q64_RS05125	COG2814	Major facilitator Superfamily
H9Q64_RS05150	COG0572	uridine kinase
H9Q64_RS05155	COG1609	Transcriptional regulator
H9Q64_RS05160	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H9Q64_RS05165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9Q64_RS05170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9Q64_RS05185	COG0110	maltose O-acetyltransferase activity
H9Q64_RS05195	COG1956	GAF domain-containing protein
H9Q64_RS05200	COG0402	S-adenosylhomocysteine deaminase activity
H9Q64_RS05205	COG0402	S-adenosylhomocysteine deaminase activity
H9Q64_RS05210	COG4166	transmembrane transport
H9Q64_RS05215	COG2508	Transcriptional regulator
H9Q64_RS05225	COG1914	H( )-stimulated, divalent metal cation uptake system
H9Q64_RS05230	COG1660	Displays ATPase and GTPase activities
H9Q64_RS05235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9Q64_RS05240	COG1116	anion transmembrane transporter activity
H9Q64_RS05330	COG5002	protein histidine kinase activity
H9Q64_RS05335	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS05340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9Q64_RS05345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q64_RS05360	COG0205	6-phosphofructokinase activity
H9Q64_RS05365	COG0587	DNA-directed DNA polymerase activity
H9Q64_RS05375	COG2814	Major facilitator Superfamily
H9Q64_RS05380	COG2252	PERMEase
H9Q64_RS05390	COG0561	phosphatase activity
H9Q64_RS05405	COG0105	UTP biosynthetic process
H9Q64_RS05450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9Q64_RS05450	COG0392	lysyltransferase activity
H9Q64_RS05455	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H9Q64_RS05460	COG0517	IMP dehydrogenase activity
H9Q64_RS05465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9Q64_RS05465	COG0574	Belongs to the PEP-utilizing enzyme family
H9Q64_RS05485	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS05490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS05495	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q64_RS05500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS05520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS05525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS05530	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9Q64_RS05530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9Q64_RS05540	COG0673	inositol 2-dehydrogenase activity
H9Q64_RS05560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9Q64_RS05565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9Q64_RS05570	COG3599	regulation of cell shape
H9Q64_RS05575	COG2302	S4 RNA-binding domain
H9Q64_RS05580	COG0762	integral membrane protein
H9Q64_RS05585	COG1799	cell septum assembly
H9Q64_RS05590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9Q64_RS05595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9Q64_RS05600	COG0849	cell division
H9Q64_RS05605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9Q64_RS05610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9Q64_RS05615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9Q64_RS05620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9Q64_RS05625	COG0768	penicillin binding
H9Q64_RS05635	COG0275	rRNA processing
H9Q64_RS05640	COG2001	Belongs to the MraZ family
H9Q64_RS05660	COG0497	DNA recombination
H9Q64_RS05665	COG1438	arginine binding
H9Q64_RS05670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9Q64_RS05675	COG0142	geranyltranstransferase activity
H9Q64_RS05680	COG1722	exodeoxyribonuclease VII activity
H9Q64_RS05685	COG1570	exodeoxyribonuclease VII activity
H9Q64_RS05690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9Q64_RS05695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q64_RS05700	COG1302	Protein conserved in bacteria
H9Q64_RS05705	COG1694	Mazg nucleotide pyrophosphohydrolase
H9Q64_RS05710	COG0006	proline dipeptidase activity
H9Q64_RS05715	COG1408	metallophosphoesterase
H9Q64_RS05720	COG3223	Belongs to the PsiE family
H9Q64_RS05725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9Q64_RS05735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9Q64_RS05750	COG0789	Transcriptional regulator
H9Q64_RS05760	COG0535	radical SAM domain protein
H9Q64_RS05765	COG1994	Peptidase M50
H9Q64_RS05770	COG1131	(ABC) transporter
H9Q64_RS05795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q64_RS05805	COG1263	PTS System
H9Q64_RS05805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS05805	COG2190	(PTS) system
H9Q64_RS05815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q64_RS05820	COG2017	converts alpha-aldose to the beta-anomer
H9Q64_RS05825	COG1609	Transcriptional regulator
H9Q64_RS05835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9Q64_RS05840	COG0802	atpase or kinase
H9Q64_RS05850	COG0280	phosphate acetyltransferase
H9Q64_RS05855	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9Q64_RS05860	COG0561	phosphatase activity
H9Q64_RS05875	COG3584	3D domain protein
H9Q64_RS05890	COG1132	(ABC) transporter
H9Q64_RS05895	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9Q64_RS05900	COG1803	Methylglyoxal synthase
H9Q64_RS05905	COG3842	ATPase activity
H9Q64_RS05915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9Q64_RS05920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9Q64_RS05925	COG0084	hydrolase, TatD family'
H9Q64_RS05930	COG3973	AAA domain
H9Q64_RS05945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q64_RS05945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q64_RS05950	COG0531	amino acid
H9Q64_RS05955	COG4975	Glucose uptake
H9Q64_RS05960	COG2205	protein histidine kinase activity
H9Q64_RS05965	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS05985	COG2855	membrane
H9Q64_RS05990	COG0659	secondary active sulfate transmembrane transporter activity
H9Q64_RS05995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9Q64_RS05995	COG0456	acetyltransferase
H9Q64_RS06005	COG3759	membrane
H9Q64_RS06015	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9Q64_RS06020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9Q64_RS06025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9Q64_RS06035	COG4608	Belongs to the ABC transporter superfamily
H9Q64_RS06040	COG0444	Belongs to the ABC transporter superfamily
H9Q64_RS06045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q64_RS06050	COG0601	transmembrane transport
H9Q64_RS06060	COG4166	transmembrane transport
H9Q64_RS06090	COG1304	FMN binding
H9Q64_RS06095	COG1454	alcohol dehydrogenase
H9Q64_RS06095	COG1012	belongs to the aldehyde dehydrogenase family
H9Q64_RS06105	COG1862	Preprotein translocase
H9Q64_RS06110	COG0343	queuine tRNA-ribosyltransferase activity
H9Q64_RS06115	COG0371	Dehydrogenase
H9Q64_RS06120	COG0765	amino acid transport
H9Q64_RS06125	COG1126	abc transporter atp-binding protein
H9Q64_RS06150	COG1215	transferase activity, transferring glycosyl groups
H9Q64_RS06170	COG1484	DNA-dependent DNA replication
H9Q64_RS06175	COG3611	Membrane attachment protein
H9Q64_RS06180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9Q64_RS06185	COG0237	dephospho-CoA kinase activity
H9Q64_RS06190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9Q64_RS06195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q64_RS06195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q64_RS06200	COG4989	oxidoreductase activity
H9Q64_RS06210	COG2217	Heavy metal translocating P-type atpase
H9Q64_RS06220	COG3158	transport of potassium into the cell
H9Q64_RS06230	COG3328	transposase activity
H9Q64_RS06240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9Q64_RS06245	COG0346	lactoylglutathione lyase activity
H9Q64_RS06265	COG1174	glycine betaine transport
H9Q64_RS06275	COG0531	amino acid
H9Q64_RS06295	COG2365	Tyrosine phosphatase family
H9Q64_RS06305	COG0681	Belongs to the peptidase S26 family
H9Q64_RS06320	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9Q64_RS06325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q64_RS06330	COG0736	holo-[acyl-carrier-protein] synthase activity
H9Q64_RS06340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9Q64_RS06345	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q64_RS06350	COG1671	Belongs to the UPF0178 family
H9Q64_RS06355	COG0187	DNA topoisomerase II activity
H9Q64_RS06375	COG3964	amidohydrolase
H9Q64_RS06390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS06420	COG3711	transcriptional antiterminator
H9Q64_RS06425	COG0673	inositol 2-dehydrogenase activity
H9Q64_RS06430	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9Q64_RS06445	COG1011	Hydrolase
H9Q64_RS06450	COG1187	pseudouridine synthase activity
H9Q64_RS06455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9Q64_RS06480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS06480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS06485	COG2188	Transcriptional regulator
H9Q64_RS06495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9Q64_RS06515	COG4166	transmembrane transport
H9Q64_RS06520	COG0765	amino acid transport
H9Q64_RS06525	COG1126	abc transporter atp-binding protein
H9Q64_RS06530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q64_RS06545	COG0495	leucyl-tRNA aminoacylation
H9Q64_RS06550	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS06550	COG1388	LysM domain
H9Q64_RS06565	COG0671	phosphoesterase, PA-phosphatase related
H9Q64_RS06570	COG1242	4 iron, 4 sulfur cluster binding
H9Q64_RS06575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H9Q64_RS06580	COG1136	(ABC) transporter
H9Q64_RS06585	COG0577	efflux transmembrane transporter activity
H9Q64_RS06590	COG1309	transcriptional regulator
H9Q64_RS06595	COG1132	(ABC) transporter
H9Q64_RS06600	COG1132	(ABC) transporter
H9Q64_RS06615	COG0477	Major facilitator Superfamily
H9Q64_RS06620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9Q64_RS06625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9Q64_RS06625	COG2755	lipolytic protein G-D-S-L family
H9Q64_RS06630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9Q64_RS06640	COG1278	Cold shock
H9Q64_RS06645	COG2816	NAD+ diphosphatase activity
H9Q64_RS06650	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q64_RS06680	COG0740	serine-type endopeptidase activity
H9Q64_RS06695	COG1481	regulation of sporulation
H9Q64_RS06705	COG1660	Displays ATPase and GTPase activities
H9Q64_RS06715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9Q64_RS06720	COG0556	nucleotide-excision repair
H9Q64_RS06725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q64_RS06735	COG1285	pathogenesis
H9Q64_RS06740	COG2217	Heavy metal translocating P-type atpase
H9Q64_RS06785	COG1054	Belongs to the UPF0176 family
H9Q64_RS06795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9Q64_RS06825	COG1428	Deoxynucleoside kinase
H9Q64_RS06835	COG0154	amidase activity
H9Q64_RS06840	COG0549	Belongs to the carbamate kinase family
H9Q64_RS06845	COG2957	Belongs to the agmatine deiminase family
H9Q64_RS06850	COG0531	amino acid
H9Q64_RS06855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9Q64_RS06860	COG2197	response regulator
H9Q64_RS06870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q64_RS06875	COG1597	lipid kinase activity
H9Q64_RS06880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q64_RS06885	COG0154	amidase activity
H9Q64_RS06890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q64_RS06895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9Q64_RS06900	COG0210	DNA helicase
H9Q64_RS06910	COG1349	DNA-binding transcription factor activity
H9Q64_RS06915	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q64_RS06920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q64_RS06920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q64_RS06920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS06930	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9Q64_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9Q64_RS06955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS06965	COG0542	response to heat
H9Q64_RS06990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H9Q64_RS06995	COG1253	flavin adenine dinucleotide binding
H9Q64_RS07000	COG0628	permease
H9Q64_RS07010	COG3557	Belongs to the UPF0374 family
H9Q64_RS07015	COG3684	Belongs to the aldolase LacD family
H9Q64_RS07025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q64_RS07025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q64_RS07025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS07040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9Q64_RS07045	COG0510	thiamine kinase activity
H9Q64_RS07050	COG4473	ABC transporter
H9Q64_RS07055	COG1131	(ABC) transporter
H9Q64_RS07060	COG0537	adenosine 5'-monophosphoramidase activity
H9Q64_RS07070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9Q64_RS07075	COG3481	metal-dependent phosphohydrolase, HD sub domain
H9Q64_RS07090	COG3679	Belongs to the UPF0342 family
H9Q64_RS07095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q64_RS07100	COG0564	pseudouridine synthase activity
H9Q64_RS07105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9Q64_RS07110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q64_RS07115	COG1438	arginine binding
H9Q64_RS07120	COG1732	Glycine betaine
H9Q64_RS07125	COG0517	IMP dehydrogenase activity
H9Q64_RS07125	COG1125	glycine betaine transport
H9Q64_RS07130	COG3594	Acyltransferase
H9Q64_RS07145	COG1187	pseudouridine synthase activity
H9Q64_RS07150	COG2244	polysaccharide biosynthetic process
H9Q64_RS07155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9Q64_RS07165	COG0346	lactoylglutathione lyase activity
H9Q64_RS07180	COG0217	transcriptional regulatory protein
H9Q64_RS07195	COG0534	Mate efflux family protein
H9Q64_RS07210	COG1349	DNA-binding transcription factor activity
H9Q64_RS07215	COG2514	catechol 2,3-dioxygenase activity
H9Q64_RS07225	COG1609	Transcriptional regulator
H9Q64_RS07245	COG0095	Lipoate-protein ligase
H9Q64_RS07250	COG0778	Nitroreductase
H9Q64_RS07255	COG1733	regulation of RNA biosynthetic process
H9Q64_RS07270	COG0583	DNA-binding transcription factor activity
H9Q64_RS07285	COG0039	L-malate dehydrogenase activity
H9Q64_RS07290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9Q64_RS07305	COG1757	Na H antiporter
H9Q64_RS07310	COG1113	amino acid transport
H9Q64_RS07325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q64_RS07335	COG0656	L-ascorbic acid biosynthetic process
H9Q64_RS07360	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS07380	COG1378	Sugar-specific transcriptional regulator TrmB
H9Q64_RS07425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q64_RS07435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q64_RS07440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q64_RS07445	COG1132	(ABC) transporter
H9Q64_RS07450	COG1132	(ABC) transporter
H9Q64_RS07460	COG1129	ABC transporter
H9Q64_RS07470	COG1309	transcriptional regulator
H9Q64_RS07530	COG0588	phosphoglycerate mutase activity
H9Q64_RS07535	COG0534	Mate efflux family protein
H9Q64_RS07560	COG2188	Transcriptional regulator
H9Q64_RS07590	COG3775	system Galactitol-specific IIC component
H9Q64_RS07595	COG3414	Phosphotransferase system galactitol-specific IIB component
H9Q64_RS07600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS07615	COG3328	transposase activity
H9Q64_RS07635	COG1070	Carbohydrate kinase
H9Q64_RS07640	COG2115	Belongs to the xylose isomerase family
H9Q64_RS07650	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS07650	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS07655	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS07705	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q64_RS07720	COG1263	PTS System
H9Q64_RS07720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS07720	COG2190	(PTS) system
H9Q64_RS07725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS07725	COG1263	PTS System
H9Q64_RS07725	COG2190	(PTS) system
H9Q64_RS07730	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H9Q64_RS07795	COG1132	(ABC) transporter
H9Q64_RS07800	COG0457	Tetratricopeptide repeat
H9Q64_RS07800	COG0463	Glycosyl transferase, family 2
H9Q64_RS07820	COG3843	relaxase mobilization nuclease domain protein
H9Q64_RS07855	COG0629	single-stranded DNA binding
H9Q64_RS07890	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS07890	COG3942	CHAP domain
H9Q64_RS07945	COG1191	sigma factor activity
H9Q64_RS07965	COG0582	viral genome integration into host DNA
H9Q64_RS07985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9Q64_RS07990	COG1780	Probably involved in ribonucleotide reductase function
H9Q64_RS07995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9Q64_RS08015	COG1285	pathogenesis
H9Q64_RS08020	COG0363	glucosamine-6-phosphate deaminase activity
H9Q64_RS08025	COG1316	TRANSCRIPTIONal
H9Q64_RS08030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9Q64_RS08035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9Q64_RS08050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9Q64_RS08055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9Q64_RS08065	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS08070	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS08085	COG1764	response to oxidative stress
H9Q64_RS08090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9Q64_RS08095	COG0363	glucosamine-6-phosphate deaminase activity
H9Q64_RS08100	COG4948	Mandelate Racemase Muconate Lactonizing
H9Q64_RS08105	COG2267	carboxylic ester hydrolase activity
H9Q64_RS08110	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9Q64_RS08115	COG1169	isochorismate synthase
H9Q64_RS08120	COG0318	PFAM AMP-dependent synthetase and ligase
H9Q64_RS08125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9Q64_RS08135	COG1388	LysM domain
H9Q64_RS08135	COG3942	CHAP domain
H9Q64_RS08140	COG3104	oligopeptide transport
H9Q64_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS08155	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H9Q64_RS08165	COG0800	Aldolase
H9Q64_RS08170	COG1414	Transcriptional regulator
H9Q64_RS08180	COG2814	Major facilitator Superfamily
H9Q64_RS08190	COG0577	efflux transmembrane transporter activity
H9Q64_RS08195	COG1136	(ABC) transporter
H9Q64_RS08195	COG0577	efflux transmembrane transporter activity
H9Q64_RS08210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9Q64_RS08215	COG0246	Mannitol dehydrogenase
H9Q64_RS08220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS08225	COG2213	PTS system mannitol-specific
H9Q64_RS08235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS08240	COG3711	transcriptional antiterminator
H9Q64_RS08250	COG0561	phosphatase activity
H9Q64_RS08255	COG0778	Nitroreductase
H9Q64_RS08260	COG1846	Transcriptional regulator
H9Q64_RS08265	COG1757	Na H antiporter
H9Q64_RS08270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9Q64_RS08290	COG0628	permease
H9Q64_RS08295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9Q64_RS08325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H9Q64_RS08330	COG1301	dicarboxylic acid transport
H9Q64_RS08335	COG0549	Belongs to the carbamate kinase family
H9Q64_RS08350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9Q64_RS08355	COG3835	regulator
H9Q64_RS08370	COG0666	response to abiotic stimulus
H9Q64_RS08385	COG5002	protein histidine kinase activity
H9Q64_RS08390	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS08395	COG1104	cysteine desulfurase activity
H9Q64_RS08400	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H9Q64_RS08405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q64_RS08410	COG0527	aspartate kinase activity
H9Q64_RS08420	COG1801	Protein of unknown function DUF72
H9Q64_RS08435	COG3397	chitin binding
H9Q64_RS08440	COG3469	chitinase activity
H9Q64_RS08445	COG2076	Multidrug Resistance protein
H9Q64_RS08450	COG2076	Multidrug Resistance protein
H9Q64_RS08455	COG0346	lactoylglutathione lyase activity
H9Q64_RS08460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H9Q64_RS08465	COG3579	cysteine-type endopeptidase activity
H9Q64_RS08470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q64_RS08485	COG2217	Heavy metal translocating P-type atpase
H9Q64_RS08500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q64_RS08505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9Q64_RS08515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS08520	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS08525	COG0626	cystathionine gamma-synthase activity
H9Q64_RS08530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9Q64_RS08540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9Q64_RS08550	COG0167	dihydroorotate dehydrogenase activity
H9Q64_RS08555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9Q64_RS08560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9Q64_RS08565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9Q64_RS08580	COG1418	mRNA catabolic process
H9Q64_RS08585	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q64_RS08590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9Q64_RS08595	COG2169	Transcriptional regulator
H9Q64_RS08600	COG0596	Alpha beta hydrolase
H9Q64_RS08610	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS08615	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS08620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS08620	COG1263	PTS System
H9Q64_RS08620	COG2190	(PTS) system
H9Q64_RS08625	COG3711	transcriptional antiterminator
H9Q64_RS08775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9Q64_RS08780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9Q64_RS08785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9Q64_RS08790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q64_RS08795	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9Q64_RS08800	COG0037	tRNA processing
H9Q64_RS08805	COG1098	S1 RNA binding domain
H9Q64_RS08815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9Q64_RS08820	COG2244	polysaccharide biosynthetic process
H9Q64_RS08825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9Q64_RS08830	COG0193	aminoacyl-tRNA hydrolase activity
H9Q64_RS08835	COG0039	L-malate dehydrogenase activity
H9Q64_RS08845	COG3942	CHAP domain
H9Q64_RS08845	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS08850	COG1827	regulation of RNA biosynthetic process
H9Q64_RS08855	COG0110	maltose O-acetyltransferase activity
H9Q64_RS08860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9Q64_RS08870	COG0765	amino acid transport
H9Q64_RS08875	COG1126	abc transporter atp-binding protein
H9Q64_RS08890	COG1114	Component of the transport system for branched-chain amino acids
H9Q64_RS08895	COG0393	Putative heavy-metal-binding
H9Q64_RS08910	COG1122	ATPase activity
H9Q64_RS08915	COG1122	ATPase activity
H9Q64_RS08920	COG1473	amidohydrolase
H9Q64_RS08930	COG0203	ribosomal protein L17
H9Q64_RS08935	COG0202	RNA polymerase activity
H9Q64_RS08940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9Q64_RS08945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9Q64_RS08950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9Q64_RS08955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9Q64_RS08960	COG0563	adenylate kinase activity
H9Q64_RS08965	COG0201	protein transport
H9Q64_RS08970	COG0200	Binds to the 23S rRNA
H9Q64_RS08975	COG1841	ribosomal large subunit assembly
H9Q64_RS08980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9Q64_RS08985	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9Q64_RS08990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9Q64_RS08995	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9Q64_RS09000	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q64_RS09005	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9Q64_RS09010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9Q64_RS09015	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9Q64_RS09020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9Q64_RS09025	COG0255	Belongs to the universal ribosomal protein uL29 family
H9Q64_RS09030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9Q64_RS09035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9Q64_RS09040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9Q64_RS09045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9Q64_RS09050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9Q64_RS09055	COG0089	rRNA binding
H9Q64_RS09060	COG0088	Forms part of the polypeptide exit tunnel
H9Q64_RS09065	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9Q64_RS09070	COG0051	transcription antitermination factor activity, RNA binding
H9Q64_RS09075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9Q64_RS09080	COG0351	phosphomethylpyrimidine kinase
H9Q64_RS09085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9Q64_RS09090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q64_RS09095	COG0049	tRNA binding
H9Q64_RS09100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9Q64_RS09105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9Q64_RS09110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS09115	COG0588	phosphoglycerate mutase activity
H9Q64_RS09120	COG1979	alcohol dehydrogenase
H9Q64_RS09125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q64_RS09130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q64_RS09135	COG1120	ATPase activity
H9Q64_RS09140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9Q64_RS09155	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9Q64_RS09160	COG1079	Belongs to the binding-protein-dependent transport system permease family
H9Q64_RS09165	COG4603	Belongs to the binding-protein-dependent transport system permease family
H9Q64_RS09170	COG3845	ABC transporter
H9Q64_RS09175	COG1744	ABC transporter substrate-binding protein PnrA-like
H9Q64_RS09180	COG1744	ABC transporter substrate-binding protein PnrA-like
H9Q64_RS09185	COG0295	cytidine deaminase activity
H9Q64_RS09190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9Q64_RS09195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9Q64_RS09200	COG1609	Transcriptional regulator
H9Q64_RS09205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9Q64_RS09210	COG2813	Specifically methylates the guanine in position
H9Q64_RS09220	COG1072	(Pantothenic acid kinase))
H9Q64_RS09225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9Q64_RS09225	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q64_RS09255	COG0604	alcohol dehydrogenase
H9Q64_RS09260	COG0640	Transcriptional regulator
H9Q64_RS09270	COG3942	CHAP domain
H9Q64_RS09270	COG1388	LysM domain
H9Q64_RS09485	COG3646	Phage regulatory protein
H9Q64_RS09500	COG1396	sequence-specific DNA binding
H9Q64_RS09515	COG0582	viral genome integration into host DNA
H9Q64_RS09525	COG4537	Required for transformation and DNA binding
H9Q64_RS09535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9Q64_RS09540	COG0531	amino acid
H9Q64_RS09545	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9Q64_RS09550	COG0577	efflux transmembrane transporter activity
H9Q64_RS09555	COG1136	(ABC) transporter
H9Q64_RS09565	COG1674	ftsk spoiiie
H9Q64_RS09570	COG1252	NADH dehydrogenase
H9Q64_RS09585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9Q64_RS09590	COG4988	ABC transporter
H9Q64_RS09595	COG1294	oxidase, subunit
H9Q64_RS09600	COG1271	oxidase subunit
H9Q64_RS09605	COG3708	Transcriptional regulator
H9Q64_RS09605	COG2207	Transcriptional regulator
H9Q64_RS09625	COG1881	PFAM PEBP family protein
H9Q64_RS09635	COG0482	sulfurtransferase activity
H9Q64_RS09645	COG1104	cysteine desulfurase activity
H9Q64_RS09650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9Q64_RS09655	COG1121	(ABC) transporter
H9Q64_RS09660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9Q64_RS09670	COG0488	(ABC) transporter
H9Q64_RS09675	COG1473	amidohydrolase
H9Q64_RS09685	COG2011	ABC-type metal ion transport system permease component
H9Q64_RS09690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q64_RS09725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9Q64_RS09735	COG1122	ATPase activity
H9Q64_RS09740	COG4720	Psort location CytoplasmicMembrane, score
H9Q64_RS09745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q64_RS09755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9Q64_RS09770	COG0789	Transcriptional regulator
H9Q64_RS09775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9Q64_RS09780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9Q64_RS09785	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q64_RS09805	COG1215	transferase activity, transferring glycosyl groups
H9Q64_RS09810	COG3475	LICD family
H9Q64_RS09820	COG1442	glycosyl transferase family 8
H9Q64_RS09820	COG1216	Glycosyl transferase, family 2
H9Q64_RS09825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9Q64_RS09840	COG3475	LICD family
H9Q64_RS09850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9Q64_RS09865	COG0438	transferase activity, transferring glycosyl groups
H9Q64_RS09865	COG1216	Glycosyl transferase, family 2
H9Q64_RS09870	COG1216	Glycosyl transferase, family 2
H9Q64_RS09870	COG0438	transferase activity, transferring glycosyl groups
H9Q64_RS09875	COG1134	teichoic acid transport
H9Q64_RS09880	COG1682	transport, permease protein
H9Q64_RS09900	COG1215	transferase activity, transferring glycosyl groups
H9Q64_RS09905	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9Q64_RS09910	COG1088	dTDP-glucose 4,6-dehydratase activity
H9Q64_RS09920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H9Q64_RS09940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9Q64_RS09945	COG1295	ribonuclease BN
H9Q64_RS09950	COG0024	Methionine aminopeptidase
H9Q64_RS09955	COG0716	FMN binding
H9Q64_RS09960	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H9Q64_RS09965	COG1309	transcriptional regulator
H9Q64_RS09970	COG2309	aminopeptidase activity
H9Q64_RS09985	COG0590	tRNA wobble adenosine to inosine editing
H9Q64_RS09995	COG0384	phenazine biosynthesis protein PhzF
H9Q64_RS10005	COG2738	Putative neutral zinc metallopeptidase
H9Q64_RS10020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS10020	COG1263	PTS System
H9Q64_RS10025	COG0346	lactoylglutathione lyase activity
H9Q64_RS10045	COG4753	response regulator
H9Q64_RS10045	COG2207	Transcriptional regulator
H9Q64_RS10050	COG2972	Histidine kinase
H9Q64_RS10060	COG1653	transport
H9Q64_RS10065	COG0395	ABC-type sugar transport system, permease component
H9Q64_RS10070	COG1175	transmembrane transport
H9Q64_RS10090	COG1132	(ABC) transporter
H9Q64_RS10115	COG0395	ABC-type sugar transport system, permease component
H9Q64_RS10120	COG1175	transmembrane transport
H9Q64_RS10130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9Q64_RS10145	COG1609	Transcriptional regulator
H9Q64_RS10155	COG0582	viral genome integration into host DNA
H9Q64_RS10210	COG4974	Belongs to the 'phage' integrase family
H9Q64_RS10215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS10245	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H9Q64_RS10270	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS10275	COG3715	PTS system
H9Q64_RS10285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9Q64_RS10290	COG2188	Transcriptional regulator
H9Q64_RS10305	COG0741	lytic transglycosylase activity
H9Q64_RS10305	COG0791	NLP P60 protein
H9Q64_RS10350	COG2946	Replication initiation factor
H9Q64_RS10360	COG0270	DNA (cytosine-5-)-methyltransferase activity
H9Q64_RS10375	COG1674	ftsk spoiiie
H9Q64_RS10415	COG0481	GTPase activity
H9Q64_RS10430	COG0542	response to heat
H9Q64_RS10445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9Q64_RS10450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9Q64_RS10460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q64_RS10470	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS10490	COG0017	Asparaginyl-tRNA synthetase
H9Q64_RS10495	COG0436	Aminotransferase
H9Q64_RS10505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9Q64_RS10505	COG1199	ATP-dependent helicase activity
H9Q64_RS10515	COG0531	amino acid
H9Q64_RS10525	COG0442	prolyl-tRNA aminoacylation
H9Q64_RS10530	COG0750	zinc metalloprotease
H9Q64_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS10555	COG1192	Involved in chromosome partitioning
H9Q64_RS10560	COG0719	Fe-S assembly protein
H9Q64_RS10570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9Q64_RS10575	COG0719	Fe-S assembly protein
H9Q64_RS10585	COG0233	cytoplasmic translational termination
H9Q64_RS10590	COG0528	UMP kinase activity
H9Q64_RS10595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9Q64_RS10600	COG0052	Belongs to the universal ribosomal protein uS2 family
H9Q64_RS10610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q64_RS10615	COG1254	Belongs to the acylphosphatase family
H9Q64_RS10620	COG0706	membrane insertase activity
H9Q64_RS10630	COG0751	glycine-tRNA ligase activity
H9Q64_RS10635	COG0752	glycyl-tRNA synthetase alpha subunit
H9Q64_RS10640	COG1381	Involved in DNA repair and RecF pathway recombination
H9Q64_RS10645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9Q64_RS10650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9Q64_RS10655	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9Q64_RS10665	COG1702	phosphate starvation-inducible protein PhoH
H9Q64_RS10670	COG1610	YqeY-like protein
H9Q64_RS10675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9Q64_RS10680	COG0735	belongs to the Fur family
H9Q64_RS10685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H9Q64_RS10690	COG0083	homoserine kinase activity
H9Q64_RS10700	COG0460	homoserine dehydrogenase
H9Q64_RS10705	COG0640	Transcriptional regulator
H9Q64_RS10710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q64_RS10715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q64_RS10720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q64_RS10735	COG0516	GMP reductase activity
H9Q64_RS10745	COG0402	S-adenosylhomocysteine deaminase activity
H9Q64_RS10760	COG1737	Transcriptional regulator
H9Q64_RS10765	COG1263	PTS System
H9Q64_RS10765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS10770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9Q64_RS10780	COG2190	(PTS) system
H9Q64_RS10780	COG1263	PTS System
H9Q64_RS10780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS10785	COG1968	undecaprenyl-diphosphatase activity
H9Q64_RS10790	COG3394	polysaccharide catabolic process
H9Q64_RS10800	COG0306	phosphate transporter
H9Q64_RS10805	COG0268	Binds directly to 16S ribosomal RNA
H9Q64_RS10810	COG1607	acyl-coa hydrolase
H9Q64_RS10815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9Q64_RS10820	COG1466	dna polymerase III delta subunit
H9Q64_RS10830	COG2131	deaminase
H9Q64_RS10835	COG1555	photosystem II stabilization
H9Q64_RS10840	COG3480	Lon protease (S16) C-terminal proteolytic domain
H9Q64_RS10845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9Q64_RS10850	COG0742	ribosomal rna small subunit methyltransferase
H9Q64_RS10855	COG4471	UPF0298 protein
H9Q64_RS10870	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H9Q64_RS10875	COG0772	Belongs to the SEDS family
H9Q64_RS10880	COG4838	Belongs to the UPF0358 family
H9Q64_RS10885	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q64_RS10890	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q64_RS10895	COG1217	gtp-binding protein TYPA
H9Q64_RS10900	COG0483	inositol monophosphate 1-phosphatase activity
H9Q64_RS10905	COG4476	Belongs to the UPF0223 family
H9Q64_RS10910	COG0038	chloride channel
H9Q64_RS10915	COG1215	transferase activity, transferring glycosyl groups
H9Q64_RS10940	COG0018	arginyl-trna synthetase
H9Q64_RS10945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9Q64_RS10950	COG0456	acetyltransferase
H9Q64_RS10960	COG1214	PFAM Peptidase M22, glycoprotease
H9Q64_RS11010	COG1682	transport, permease protein
H9Q64_RS11015	COG1134	teichoic acid transport
H9Q64_RS11015	COG1388	LysM domain
H9Q64_RS11020	COG0562	UDP-galactopyranose mutase
H9Q64_RS11035	COG1216	Glycosyl transferase, family 2
H9Q64_RS11040	COG1215	transferase activity, transferring glycosyl groups
H9Q64_RS11040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9Q64_RS11045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9Q64_RS11050	COG4589	Belongs to the CDS family
H9Q64_RS11055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9Q64_RS11060	COG1464	Belongs to the NlpA lipoprotein family
H9Q64_RS11065	COG2011	ABC-type metal ion transport system permease component
H9Q64_RS11070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q64_RS11075	COG0509	glycine decarboxylation via glycine cleavage system
H9Q64_RS11080	COG1393	Belongs to the ArsC family
H9Q64_RS11085	COG0772	Belongs to the SEDS family
H9Q64_RS11115	COG1396	sequence-specific DNA binding
H9Q64_RS11145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9Q64_RS11150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9Q64_RS11155	COG0009	L-threonylcarbamoyladenylate synthase
H9Q64_RS11160	COG2890	protein-(glutamine-N5) methyltransferase activity
H9Q64_RS11165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9Q64_RS11170	COG1435	thymidine kinase activity
H9Q64_RS11175	COG1053	succinate dehydrogenase
H9Q64_RS11180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q64_RS11190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q64_RS11190	COG0493	'glutamate synthase
H9Q64_RS11195	COG0543	2 iron, 2 sulfur cluster binding
H9Q64_RS11200	COG0716	FMN binding
H9Q64_RS11205	COG3608	succinylglutamate desuccinylase aspartoacylase
H9Q64_RS11205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H9Q64_RS11210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9Q64_RS11235	COG0746	molybdenum cofactor guanylyltransferase activity
H9Q64_RS11245	COG3608	succinylglutamate desuccinylase aspartoacylase
H9Q64_RS11245	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H9Q64_RS11260	COG0251	oxidation-reduction process
H9Q64_RS11265	COG0549	Belongs to the carbamate kinase family
H9Q64_RS11270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9Q64_RS11275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q64_RS11290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q64_RS11290	COG0493	'glutamate synthase
H9Q64_RS11295	COG0402	S-adenosylhomocysteine deaminase activity
H9Q64_RS11305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9Q64_RS11310	COG3442	glutamine amidotransferase
H9Q64_RS11315	COG1957	nucleoside hydrolase
H9Q64_RS11325	COG1482	cell wall glycoprotein biosynthetic process
H9Q64_RS11340	COG1132	(ABC) transporter
H9Q64_RS11355	COG0194	GDP metabolic process
H9Q64_RS11360	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS11365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS11365	COG1263	PTS System
H9Q64_RS11365	COG2190	(PTS) system
H9Q64_RS11370	COG3711	transcriptional antiterminator
H9Q64_RS11380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9Q64_RS11385	COG0628	permease
H9Q64_RS11400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9Q64_RS11405	COG4836	Membrane
H9Q64_RS11410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9Q64_RS11415	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9Q64_RS11420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9Q64_RS11425	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9Q64_RS11430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9Q64_RS11435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9Q64_RS11440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9Q64_RS11445	COG0356	it plays a direct role in the translocation of protons across the membrane
H9Q64_RS11450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9Q64_RS11455	COG0557	exoribonuclease II activity
H9Q64_RS11465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9Q64_RS11470	COG2388	GCN5-related N-acetyl-transferase
H9Q64_RS11475	COG3592	Divergent 4Fe-4S mono-cluster
H9Q64_RS11485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9Q64_RS11490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9Q64_RS11495	COG2246	polysaccharide biosynthetic process
H9Q64_RS11500	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9Q64_RS11500	COG3942	CHAP domain
H9Q64_RS11520	COG0459	protein refolding
H9Q64_RS11525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9Q64_RS11540	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H9Q64_RS11545	COG0488	(ABC) transporter
H9Q64_RS11555	COG4175	Glycine betaine
H9Q64_RS11555	COG3448	diguanylate cyclase activity
H9Q64_RS11570	COG1597	lipid kinase activity
H9Q64_RS11575	COG3835	regulator
H9Q64_RS11580	COG1929	Belongs to the glycerate kinase type-1 family
H9Q64_RS11585	COG2610	gluconate transmembrane transporter activity
H9Q64_RS11590	COG0398	Pfam SNARE associated Golgi protein
H9Q64_RS11595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9Q64_RS11600	COG1177	transmembrane transport
H9Q64_RS11605	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9Q64_RS11610	COG3842	ATPase activity
H9Q64_RS11620	COG0604	alcohol dehydrogenase
H9Q64_RS11630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9Q64_RS11635	COG4684	Psort location CytoplasmicMembrane, score
H9Q64_RS11840	COG3935	DnaD domain protein
H9Q64_RS11845	COG3723	Recombinational DNA repair protein, rece pathway
H9Q64_RS11850	COG5377	YqaJ viral recombinase family
H9Q64_RS11935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9Q64_RS11945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9Q64_RS11955	COG3142	Participates in the control of copper homeostasis
H9Q64_RS11960	COG2239	Acts as a magnesium transporter
H9Q64_RS11965	COG0564	pseudouridine synthase activity
H9Q64_RS11970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9Q64_RS11975	COG2357	RelA SpoT domain protein
H9Q64_RS11980	COG4116	CYTH
H9Q64_RS11990	COG1164	Oligoendopeptidase f
H9Q64_RS12000	COG4862	establishment of competence for transformation
H9Q64_RS12005	COG1393	Belongs to the ArsC family
H9Q64_RS12010	COG0180	Tryptophanyl-tRNA synthetase
H9Q64_RS12015	COG1132	(ABC) transporter
H9Q64_RS12130	COG0740	serine-type endopeptidase activity
H9Q64_RS12190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9Q64_RS12315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS12320	COG1132	(ABC) transporter
H9Q64_RS12335	COG0419	ATPase involved in DNA repair
H9Q64_RS12340	COG0420	3'-5' exonuclease activity
H9Q64_RS12345	COG0204	Acyl-transferase
H9Q64_RS12350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9Q64_RS12355	COG2827	Endonuclease containing a URI domain
H9Q64_RS12360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9Q64_RS12370	COG0494	nUDIX hydrolase
H9Q64_RS12380	COG3853	Toxic anion resistance protein (TelA)
H9Q64_RS12405	COG1194	a g-specific adenine glycosylase
H9Q64_RS12410	COG2137	regulation of response to DNA damage stimulus
H9Q64_RS12415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q64_RS12420	COG2261	transglycosylase associated protein
H9Q64_RS12425	COG3250	beta-galactosidase activity
H9Q64_RS12430	COG0531	amino acid
H9Q64_RS12435	COG2207	Transcriptional regulator
H9Q64_RS12435	COG1917	Cupin 2, conserved barrel domain protein
H9Q64_RS12440	COG0222	ribosome binding
H9Q64_RS12445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9Q64_RS12450	COG0081	regulation of translation
H9Q64_RS12455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9Q64_RS12460	COG0488	(ABC) transporter
H9Q64_RS12465	COG1760	l-serine dehydratase
H9Q64_RS12470	COG1760	l-serine dehydratase
H9Q64_RS12480	COG1363	Peptidase, m42
H9Q64_RS12485	COG4166	transmembrane transport
H9Q64_RS12500	COG0250	Participates in transcription elongation, termination and antitermination
H9Q64_RS12505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9Q64_RS12510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q64_RS12520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9Q64_RS12530	COG0708	Exodeoxyribonuclease III
H9Q64_RS12560	COG0095	Lipoate-protein ligase
H9Q64_RS12565	COG1234	tRNA 3'-trailer cleavage
H9Q64_RS12575	COG1363	Peptidase, m42
H9Q64_RS12580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H9Q64_RS12585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q64_RS12590	COG1696	Membrane protein involved in D-alanine export
H9Q64_RS12595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9Q64_RS12605	COG0577	efflux transmembrane transporter activity
H9Q64_RS12610	COG1136	(ABC) transporter
H9Q64_RS12615	COG1328	CTP reductase activity
H9Q64_RS12620	COG0602	queuosine metabolic process
H9Q64_RS12630	COG0390	transport system, permease component
H9Q64_RS12635	COG4619	ABC transporter
H9Q64_RS12645	COG4467	Involved in initiation control of chromosome replication
H9Q64_RS12650	COG1774	PSP1 C-terminal conserved region
H9Q64_RS12655	COG0470	DNA polymerase III
H9Q64_RS12660	COG3870	Protein conserved in bacteria
H9Q64_RS12665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9Q64_RS12670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9Q64_RS12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9Q64_RS12685	COG1122	ATPase activity
H9Q64_RS12700	COG0477	Major facilitator Superfamily
H9Q64_RS12705	COG2814	Major facilitator Superfamily
H9Q64_RS12710	COG1733	regulation of RNA biosynthetic process
H9Q64_RS12715	COG0351	phosphomethylpyrimidine kinase
H9Q64_RS12720	COG0352	thiamine-phosphate diphosphorylase activity
H9Q64_RS12725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H9Q64_RS12735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9Q64_RS12740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9Q64_RS12745	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H9Q64_RS12750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9Q64_RS12765	COG3189	MarR family transcriptional regulator
H9Q64_RS12780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9Q64_RS12785	COG1940	carbohydrate kinase activity
H9Q64_RS12800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9Q64_RS12805	COG1073	alpha beta
H9Q64_RS12835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q64_RS12840	COG0768	penicillin binding
H9Q64_RS12845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q64_RS12850	COG1942	4-Oxalocrotonate Tautomerase
H9Q64_RS12880	COG0217	transcriptional regulatory protein
H9Q64_RS12885	COG1323	Belongs to the UPF0348 family
H9Q64_RS12890	COG2226	methyltransferase
H9Q64_RS12895	COG0799	negative regulation of ribosome biogenesis
H9Q64_RS12900	COG1713	HD superfamily hydrolase involved in NAD metabolism
H9Q64_RS12905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9Q64_RS12910	COG1534	Rna-binding protein
H9Q64_RS12915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9Q64_RS12925	COG0825	malonyl-CoA metabolic process
H9Q64_RS12930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9Q64_RS12935	COG0439	Biotin carboxylase
H9Q64_RS12940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9Q64_RS12950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9Q64_RS12960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9Q64_RS12975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q64_RS12980	COG1846	Transcriptional regulator
H9Q64_RS12985	COG4703	Protein of unknown function (DUF1797)
H9Q64_RS12990	COG2084	Dehydrogenase
H9Q64_RS12995	COG0438	transferase activity, transferring glycosyl groups
H9Q64_RS13035	COG1098	S1 RNA binding domain
H9Q64_RS13040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9Q64_RS13055	COG0492	ferredoxin-NADP+ reductase activity
H9Q64_RS13065	COG0737	Belongs to the 5'-nucleotidase family
H9Q64_RS13085	COG1175	transmembrane transport
H9Q64_RS13090	COG3842	ATPase activity
H9Q64_RS13095	COG0463	Glycosyl transferase, family 2
H9Q64_RS13100	COG4841	protein insertion into membrane
H9Q64_RS13105	COG0569	domain protein
H9Q64_RS13110	COG2197	response regulator
H9Q64_RS13115	COG4585	Histidine kinase
H9Q64_RS13125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9Q64_RS13130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9Q64_RS13140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9Q64_RS13145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9Q64_RS13160	COG2832	Protein of unknown function (DUF454)
H9Q64_RS13165	COG5503	Protein of unknown function (DUF1447)
H9Q64_RS13175	COG1278	Cold shock
H9Q64_RS13180	COG2003	Belongs to the UPF0758 family
H9Q64_RS13185	COG1388	LysM domain
H9Q64_RS13185	COG3942	CHAP domain
H9Q64_RS13430	COG1396	sequence-specific DNA binding
H9Q64_RS13440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q64_RS13450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q64_RS13455	COG0285	dihydrofolate synthase activity
H9Q64_RS13470	COG0525	valine-tRNA ligase activity
H9Q64_RS13475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H9Q64_RS13480	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H9Q64_RS13485	COG0301	tRNA thio-modification
H9Q64_RS13490	COG2252	PERMEase
H9Q64_RS13595	COG1396	sequence-specific DNA binding
H9Q64_RS13605	COG4221	oxidoreductase activity
H9Q64_RS13610	COG0110	maltose O-acetyltransferase activity
H9Q64_RS13615	COG0583	DNA-binding transcription factor activity
H9Q64_RS13620	COG4975	Glucose uptake
H9Q64_RS13625	COG1869	D-ribose catabolic process
H9Q64_RS13635	COG1609	Transcriptional regulator
H9Q64_RS13640	COG0657	acetylesterase activity
H9Q64_RS13655	COG3711	transcriptional antiterminator
H9Q64_RS13680	COG1834	amidinotransferase
H9Q64_RS13685	COG1785	Belongs to the alkaline phosphatase family
H9Q64_RS13690	COG1193	negative regulation of DNA recombination
H9Q64_RS13705	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS13710	COG3715	PTS system
H9Q64_RS13715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS13745	COG0577	efflux transmembrane transporter activity
H9Q64_RS13750	COG1136	(ABC) transporter
H9Q64_RS13755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9Q64_RS13765	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q64_RS13775	COG1937	Protein conserved in bacteria
H9Q64_RS13785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9Q64_RS13790	COG2508	Transcriptional regulator
H9Q64_RS13795	COG3257	ureidoglycine aminohydrolase activity
H9Q64_RS13800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q64_RS13805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9Q64_RS13810	COG1953	Uracil, thiamine, allantoin
H9Q64_RS13820	COG1846	Transcriptional regulator
H9Q64_RS13840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H9Q64_RS13870	COG2508	Transcriptional regulator
H9Q64_RS13880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9Q64_RS13885	COG1304	FMN binding
H9Q64_RS13900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q64_RS13905	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9Q64_RS13915	COG1715	Restriction endonuclease
H9Q64_RS13945	COG1823	symporter activity
H9Q64_RS13955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9Q64_RS13960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9Q64_RS13965	COG0577	efflux transmembrane transporter activity
H9Q64_RS13965	COG1136	(ABC) transporter
H9Q64_RS13980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q64_RS13990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9Q64_RS13995	COG1363	Peptidase, m42
H9Q64_RS14005	COG4166	transmembrane transport
H9Q64_RS14010	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q64_RS14045	COG3764	Sortase (surface protein transpeptidase)
H9Q64_RS14055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9Q64_RS14080	COG1185	polyribonucleotide nucleotidyltransferase activity
H9Q64_RS14085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9Q64_RS14090	COG0242	peptide deformylase activity
H9Q64_RS14110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9Q64_RS14115	COG1268	BioY protein
H9Q64_RS14120	COG0681	Belongs to the peptidase S26 family
H9Q64_RS14135	COG4493	Belongs to the UPF0637 family
H9Q64_RS14145	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q64_RS14150	COG4166	transmembrane transport
H9Q64_RS14155	COG4607	ABC-type enterochelin transport system periplasmic component
H9Q64_RS14160	COG4604	ABC transporter, ATP-binding protein
H9Q64_RS14165	COG4605	iron ion homeostasis
H9Q64_RS14170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q64_RS14180	COG2918	glutathione biosynthetic process
H9Q64_RS14180	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q64_RS14190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q64_RS14205	COG0552	protein localization to endoplasmic reticulum
H9Q64_RS14210	COG0561	phosphatase activity
H9Q64_RS14215	COG1196	nuclear chromosome segregation
H9Q64_RS14220	COG0571	ribonuclease III activity
H9Q64_RS14240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H9Q64_RS14255	COG0601	transmembrane transport
H9Q64_RS14260	COG4608	Belongs to the ABC transporter superfamily
H9Q64_RS14270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q64_RS14275	COG0416	fatty acid biosynthetic process
H9Q64_RS14280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9Q64_RS14285	COG1461	Dihydroxyacetone kinase
H9Q64_RS14300	COG1131	(ABC) transporter
H9Q64_RS14315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9Q64_RS14325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9Q64_RS14330	COG1162	GTPase activity
H9Q64_RS14335	COG0515	serine threonine protein kinase
H9Q64_RS14335	COG2815	serine threonine protein kinase
H9Q64_RS14345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9Q64_RS14345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q64_RS14350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9Q64_RS14360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9Q64_RS14370	COG1758	RNA polymerase activity
H9Q64_RS14375	COG0194	GDP metabolic process
H9Q64_RS14405	COG0800	Aldolase
H9Q64_RS14410	COG1312	Catalyzes the dehydration of D-mannonate
H9Q64_RS14420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS14425	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS14435	COG0371	Dehydrogenase
H9Q64_RS14445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
H9Q64_RS14450	COG1737	Transcriptional regulator
H9Q64_RS14460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9Q64_RS14470	COG1426	Protein conserved in bacteria
H9Q64_RS14475	COG0612	Peptidase, M16
H9Q64_RS14480	COG0612	Peptidase, M16
H9Q64_RS14485	COG1970	mechanosensitive ion channel activity
H9Q64_RS14505	COG2188	Transcriptional regulator
H9Q64_RS14510	COG1554	hydrolase, family 65, central catalytic
H9Q64_RS14515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q64_RS14525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9Q64_RS14535	COG0424	maF-like protein
H9Q64_RS14540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9Q64_RS14545	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9Q64_RS14550	COG4550	Control of competence regulator ComK, YlbF/YmcA
H9Q64_RS14555	COG1692	metallophosphoesterase
H9Q64_RS14560	COG1418	mRNA catabolic process
H9Q64_RS14570	COG2723	6-phospho-beta-galactosidase activity
H9Q64_RS14590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9Q64_RS14595	COG1546	Belongs to the CinA family
H9Q64_RS14595	COG1058	Belongs to the CinA family
H9Q64_RS14600	COG2433	Pfam Transposase IS66
H9Q64_RS14605	COG2910	NAD(P)H-binding
H9Q64_RS14610	COG1959	2 iron, 2 sulfur cluster binding
H9Q64_RS14685	COG1335	isochorismatase
H9Q64_RS14690	COG1346	cytolysis
H9Q64_RS14700	COG3279	Response regulator of the LytR AlgR family
H9Q64_RS14705	COG3275	phosphorelay sensor kinase activity
H9Q64_RS14715	COG2011	ABC-type metal ion transport system permease component
H9Q64_RS14730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q64_RS14735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q64_RS14750	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9Q64_RS14750	COG3443	Belongs to the bacterial solute-binding protein 9 family
H9Q64_RS14755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9Q64_RS14760	COG0842	Transport permease protein
H9Q64_RS14765	COG1131	(ABC) transporter
H9Q64_RS14775	COG0494	nUDIX hydrolase
H9Q64_RS14800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9Q64_RS14805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9Q64_RS14810	COG0783	Belongs to the Dps family
H9Q64_RS14820	COG1070	Carbohydrate kinase
H9Q64_RS14825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9Q64_RS14830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9Q64_RS14835	COG0085	RNA polymerase activity
H9Q64_RS14860	COG1316	TRANSCRIPTIONal
H9Q64_RS14875	COG1575	Belongs to the MenA family. Type 1 subfamily
H9Q64_RS14885	COG4939	FMN-binding domain protein
H9Q64_RS14905	COG0142	geranyltranstransferase activity
H9Q64_RS14930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9Q64_RS14935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9Q64_RS14940	COG0302	gtp cyclohydrolase
H9Q64_RS14950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9Q64_RS14955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9Q64_RS14985	COG0826	peptidase U32
H9Q64_RS14990	COG0826	peptidase U32
H9Q64_RS15000	COG0542	response to heat
H9Q64_RS15005	COG4463	regulation of RNA biosynthetic process
H9Q64_RS15010	COG0626	cystathionine gamma-synthase activity
H9Q64_RS15015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q64_RS15020	COG1737	Transcriptional regulator
H9Q64_RS15090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9Q64_RS15095	COG0517	IMP dehydrogenase activity
H9Q64_RS15095	COG0516	GMP reductase activity
H9Q64_RS15110	COG0012	GTP binding
H9Q64_RS15115	COG4481	Protein conserved in bacteria
H9Q64_RS15120	COG1475	DNA binding
H9Q64_RS15125	COG1192	Involved in chromosome partitioning
H9Q64_RS15130	COG0357	Ribosomal RNA small subunit methyltransferase G
H9Q64_RS15160	COG3730	PTS system glucitol sorbitol-specific
H9Q64_RS15180	COG0445	tRNA wobble uridine modification
H9Q64_RS15185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9Q64_RS15195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H9Q64_RS15225	COG3052	prosthetic group binding
H9Q64_RS15230	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
H9Q64_RS15235	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H9Q64_RS15240	COG0511	ligase activity, forming carbon-carbon bonds
H9Q64_RS15250	COG2851	Citrate transporter
H9Q64_RS15260	COG0745	RESPONSE REGULATOR receiver
H9Q64_RS15270	COG0706	membrane insertase activity
H9Q64_RS15275	COG0594	ribonuclease P activity
H9Q64_RS15280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9Q64_RS15285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9Q64_RS15290	COG0592	DNA-directed DNA polymerase activity
H9Q64_RS15295	COG2501	S4 domain
H9Q64_RS15300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9Q64_RS15305	COG0187	DNA topoisomerase II activity
H9Q64_RS15315	COG0360	Binds together with S18 to 16S ribosomal RNA
H9Q64_RS15320	COG0629	single-stranded DNA binding
H9Q64_RS15325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9Q64_RS15340	COG0359	binds to the 23S rRNA
H9Q64_RS15345	COG0305	Participates in initiation and elongation during chromosome replication
H9Q64_RS15350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9Q64_RS15365	COG0488	(ABC) transporter
H9Q64_RS15370	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9Q64_RS15370	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9Q64_RS15375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS15375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q64_RS15385	COG3715	PTS system
H9Q64_RS15390	COG3716	PTS system mannose fructose sorbose family IID component
H9Q64_RS15410	COG1737	Transcriptional regulator
H9Q64_RS15415	COG1263	PTS System
H9Q64_RS15415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q64_RS15420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9Q64_RS15425	COG0251	oxidation-reduction process
H9Q64_RS15430	COG0392	lysyltransferase activity
H9Q64_RS15430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9Q64_RS15455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9Q64_RS15460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9Q64_RS15465	COG0756	dUTP diphosphatase activity
H9Q64_RS15475	COG4956	integral membrane protein (PIN domain superfamily)
H9Q64_RS15480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9Q64_RS15485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9Q64_RS15490	COG1045	serine acetyltransferase
H9Q64_RS15495	COG0215	cysteine-tRNA ligase activity
H9Q64_RS15500	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H9Q64_RS15505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q64_RS15510	COG3688	RNA-binding protein containing a PIN domain
H9Q64_RS15520	COG4466	Protein conserved in bacteria
H9Q64_RS15525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9Q64_RS15530	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9Q64_RS15530	COG3443	Belongs to the bacterial solute-binding protein 9 family
H9Q64_RS15535	COG1121	(ABC) transporter
H9Q64_RS15540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9Q64_RS15545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q64_RS15550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9Q64_RS15555	COG0737	Belongs to the 5'-nucleotidase family
H9Q64_RS15560	COG4166	transmembrane transport
H9Q64_RS15565	COG4224	UPF0291 protein
H9Q64_RS15570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9Q64_RS15575	COG0632	four-way junction helicase activity
H9Q64_RS15580	COG2255	four-way junction helicase activity
H9Q64_RS15585	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H9Q64_RS15590	COG3408	Glycogen debranching enzyme
H9Q64_RS15590	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H9Q64_RS15600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9Q64_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q64_RS15630	COG2261	transglycosylase associated protein
H9Q64_RS15635	COG2814	Major facilitator Superfamily
H9Q64_RS15660	COG1597	lipid kinase activity
H9Q64_RS15680	COG2116	formate transmembrane transporter activity
H9Q64_RS15690	COG2964	Protein conserved in bacteria
H9Q64_RS15700	COG1760	l-serine dehydratase
H9Q64_RS15705	COG1760	l-serine dehydratase
H9Q64_RS15710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9Q64_RS15730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q64_RS15745	COG1438	arginine binding
H9Q64_RS15750	COG1438	arginine binding
H9Q64_RS15755	COG2235	arginine
H9Q64_RS15760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9Q64_RS15765	COG0549	Belongs to the carbamate kinase family
H9Q64_RS15775	COG1288	antiporter activity
H9Q64_RS15785	COG3561	AntA/AntB antirepressor
H9Q64_RS15790	COG0582	viral genome integration into host DNA
H9Q64_RS15805	COG1396	sequence-specific DNA binding