locus-tag	class	description
CWC51_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWC51_RS00010	COG0592	DNA-directed DNA polymerase activity
CWC51_RS00015	COG2501	S4 domain
CWC51_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWC51_RS00025	COG0187	DNA topoisomerase II activity
CWC51_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
CWC51_RS00040	COG0629	single-stranded DNA binding
CWC51_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWC51_RS00055	COG0359	binds to the 23S rRNA
CWC51_RS00060	COG0305	Participates in initiation and elongation during chromosome replication
CWC51_RS00065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CWC51_RS00075	COG0488	(ABC) transporter
CWC51_RS00085	COG0028	Belongs to the TPP enzyme family
CWC51_RS00155	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS00165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS00165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS00175	COG3328	transposase activity
CWC51_RS00215	COG1674	ftsk spoiiie
CWC51_RS00220	COG2946	Replication initiation factor
CWC51_RS00265	COG0791	NLP P60 protein
CWC51_RS00265	COG0741	lytic transglycosylase activity
CWC51_RS00330	COG0582	viral genome integration into host DNA
CWC51_RS00340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWC51_RS00340	COG0519	Catalyzes the synthesis of GMP from XMP
CWC51_RS00345	COG1072	(Pantothenic acid kinase))
CWC51_RS00350	COG2813	Specifically methylates the guanine in position
CWC51_RS00355	COG1609	Transcriptional regulator
CWC51_RS00360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CWC51_RS00365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CWC51_RS00370	COG0295	cytidine deaminase activity
CWC51_RS00375	COG1744	ABC transporter substrate-binding protein PnrA-like
CWC51_RS00380	COG3845	ABC transporter
CWC51_RS00385	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWC51_RS00390	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWC51_RS00395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CWC51_RS00405	COG0813	purine-nucleoside phosphorylase activity
CWC51_RS00410	COG0588	phosphoglycerate mutase activity
CWC51_RS00420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CWC51_RS00425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CWC51_RS00430	COG0049	tRNA binding
CWC51_RS00435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWC51_RS00440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWC51_RS00445	COG0051	transcription antitermination factor activity, RNA binding
CWC51_RS00450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWC51_RS00455	COG0088	Forms part of the polypeptide exit tunnel
CWC51_RS00460	COG0089	rRNA binding
CWC51_RS00465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWC51_RS00475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWC51_RS00480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWC51_RS00485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWC51_RS00490	COG0255	Belongs to the universal ribosomal protein uL29 family
CWC51_RS00495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWC51_RS00500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWC51_RS00505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWC51_RS00510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWC51_RS00515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWC51_RS00520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWC51_RS00525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CWC51_RS00530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CWC51_RS00535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWC51_RS00540	COG1841	ribosomal large subunit assembly
CWC51_RS00545	COG0200	Binds to the 23S rRNA
CWC51_RS00550	COG0201	protein transport
CWC51_RS00555	COG0563	adenylate kinase activity
CWC51_RS00560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWC51_RS00565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWC51_RS00570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWC51_RS00575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWC51_RS00580	COG0202	RNA polymerase activity
CWC51_RS00585	COG0203	ribosomal protein L17
CWC51_RS00590	COG1122	ATPase activity
CWC51_RS00595	COG1122	ATPase activity
CWC51_RS00605	COG0101	tRNA pseudouridine synthase activity
CWC51_RS00615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWC51_RS00625	COG1461	Dihydroxyacetone kinase
CWC51_RS00630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWC51_RS00635	COG0416	fatty acid biosynthetic process
CWC51_RS00640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWC51_RS00650	COG4608	Belongs to the ABC transporter superfamily
CWC51_RS00655	COG0601	transmembrane transport
CWC51_RS00670	COG0571	ribonuclease III activity
CWC51_RS00675	COG1196	nuclear chromosome segregation
CWC51_RS00680	COG0561	phosphatase activity
CWC51_RS00685	COG0552	protein localization to endoplasmic reticulum
CWC51_RS00690	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWC51_RS00690	COG2918	glutathione biosynthetic process
CWC51_RS00700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWC51_RS00705	COG4605	iron ion homeostasis
CWC51_RS00710	COG4604	ABC transporter, ATP-binding protein
CWC51_RS00715	COG4607	ABC-type enterochelin transport system periplasmic component
CWC51_RS00740	COG4886	Leucine-rich repeat (LRR) protein
CWC51_RS00740	COG4932	domain protein
CWC51_RS00755	COG3328	transposase activity
CWC51_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
CWC51_RS00805	COG1268	BioY protein
CWC51_RS00810	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWC51_RS00825	COG0561	phosphatase activity
CWC51_RS00830	COG1692	metallophosphoesterase
CWC51_RS00840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CWC51_RS00850	COG0424	maF-like protein
CWC51_RS00855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS00855	COG1263	PTS System
CWC51_RS00860	COG2188	Transcriptional regulator
CWC51_RS00870	COG0632	four-way junction helicase activity
CWC51_RS00875	COG2255	four-way junction helicase activity
CWC51_RS00885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWC51_RS00895	COG3328	transposase activity
CWC51_RS00900	COG1114	Component of the transport system for branched-chain amino acids
CWC51_RS00910	COG1113	amino acid transport
CWC51_RS00915	COG1126	abc transporter atp-binding protein
CWC51_RS00920	COG0765	amino acid transport
CWC51_RS00930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CWC51_RS00935	COG0110	maltose O-acetyltransferase activity
CWC51_RS00940	COG1827	regulation of RNA biosynthetic process
CWC51_RS00945	COG0242	peptide deformylase activity
CWC51_RS00950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CWC51_RS00955	COG1185	polyribonucleotide nucleotidyltransferase activity
CWC51_RS00965	COG3158	transport of potassium into the cell
CWC51_RS00970	COG1253	flavin adenine dinucleotide binding
CWC51_RS00975	COG0534	Mate efflux family protein
CWC51_RS00985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CWC51_RS00990	COG1187	pseudouridine synthase activity
CWC51_RS00995	COG1011	Hydrolase
CWC51_RS01000	COG0572	uridine kinase
CWC51_RS01025	COG1671	Belongs to the UPF0178 family
CWC51_RS01035	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWC51_RS01040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWC51_RS01050	COG0736	holo-[acyl-carrier-protein] synthase activity
CWC51_RS01055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWC51_RS01060	COG2337	Toxic component of a toxin-antitoxin (TA) module
CWC51_RS01065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWC51_RS01070	COG3321	synthase
CWC51_RS01070	COG0604	alcohol dehydrogenase
CWC51_RS01080	COG0531	amino acid
CWC51_RS01105	COG1174	glycine betaine transport
CWC51_RS01140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CWC51_RS01155	COG0343	queuine tRNA-ribosyltransferase activity
CWC51_RS01160	COG1862	Preprotein translocase
CWC51_RS01165	COG1454	alcohol dehydrogenase
CWC51_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
CWC51_RS01170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWC51_RS01200	COG1917	Cupin 2, conserved barrel domain protein
CWC51_RS01200	COG2207	Transcriptional regulator
CWC51_RS01205	COG1070	Carbohydrate kinase
CWC51_RS01210	COG4806	L-rhamnose isomerase
CWC51_RS01215	COG0235	Class ii aldolase
CWC51_RS01220	COG3254	rhamnose metabolic process
CWC51_RS01225	COG1454	alcohol dehydrogenase
CWC51_RS01230	COG1414	Transcriptional regulator
CWC51_RS01235	COG0800	Aldolase
CWC51_RS01245	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CWC51_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
CWC51_RS01255	COG1304	FMN binding
CWC51_RS01270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWC51_RS01275	COG1428	Deoxynucleoside kinase
CWC51_RS01290	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWC51_RS01295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWC51_RS01300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWC51_RS01330	COG0824	Thioesterase
CWC51_RS01335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWC51_RS01365	COG1363	Peptidase, m42
CWC51_RS01370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWC51_RS01375	COG0589	response to stress
CWC51_RS01380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWC51_RS01385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWC51_RS01390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CWC51_RS01415	COG3328	transposase activity
CWC51_RS01430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS01435	COG3414	Phosphotransferase system galactitol-specific IIB component
CWC51_RS01440	COG3775	system Galactitol-specific IIC component
CWC51_RS01465	COG1105	Belongs to the carbohydrate kinase PfkB family
CWC51_RS01470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS01470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS01470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS01475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS01475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS01475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS01480	COG3684	Belongs to the aldolase LacD family
CWC51_RS01555	COG1368	sulfuric ester hydrolase activity
CWC51_RS01565	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CWC51_RS01575	COG0101	tRNA pseudouridine synthase activity
CWC51_RS01590	COG3328	transposase activity
CWC51_RS01610	COG0667	Aldo Keto reductase
CWC51_RS01615	COG2186	Transcriptional regulator
CWC51_RS01620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS01625	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS01635	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWC51_RS01640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS01655	COG1063	alcohol dehydrogenase
CWC51_RS01670	COG4716	Myosin-crossreactive antigen
CWC51_RS01710	COG1113	amino acid transport
CWC51_RS01735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWC51_RS01745	COG3052	prosthetic group binding
CWC51_RS01805	COG1051	belongs to the nudix hydrolase family
CWC51_RS01810	COG1846	Transcriptional regulator
CWC51_RS01835	COG2252	PERMEase
CWC51_RS01840	COG0366	Alpha amylase catalytic
CWC51_RS01845	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS01855	COG2190	(PTS) system
CWC51_RS01855	COG1263	PTS System
CWC51_RS01860	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS01870	COG1902	pentaerythritol trinitrate reductase activity
CWC51_RS01880	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS01890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWC51_RS01895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWC51_RS01900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWC51_RS01910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWC51_RS01920	COG1937	Protein conserved in bacteria
CWC51_RS01925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWC51_RS01930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS01935	COG3973	AAA domain
CWC51_RS01960	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CWC51_RS01965	COG2376	Dihydroxyacetone kinase
CWC51_RS01970	COG1461	Dihydroxyacetone kinase
CWC51_RS01980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWC51_RS01990	COG1131	(ABC) transporter
CWC51_RS01995	COG1309	transcriptional regulator
CWC51_RS02015	COG0531	amino acid
CWC51_RS02020	COG1757	Na H antiporter
CWC51_RS02025	COG1609	Transcriptional regulator
CWC51_RS02035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS02045	COG1263	PTS System
CWC51_RS02045	COG2190	(PTS) system
CWC51_RS02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS02070	COG3479	Phenolic acid decarboxylase
CWC51_RS02075	COG1695	Transcriptional regulator
CWC51_RS02085	COG2814	Major facilitator Superfamily
CWC51_RS02105	COG0163	prenyltransferase activity
CWC51_RS02110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CWC51_RS02120	COG1136	(ABC) transporter
CWC51_RS02120	COG0577	efflux transmembrane transporter activity
CWC51_RS02140	COG1811	Na channel or pump
CWC51_RS02175	COG1136	(ABC) transporter
CWC51_RS02190	COG3942	CHAP domain
CWC51_RS02190	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWC51_RS02195	COG1263	PTS System
CWC51_RS02195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS02195	COG2190	(PTS) system
CWC51_RS02200	COG1869	D-ribose catabolic process
CWC51_RS02210	COG1609	Transcriptional regulator
CWC51_RS02230	COG0366	Alpha amylase catalytic
CWC51_RS02235	COG0628	permease
CWC51_RS02240	COG3443	Belongs to the bacterial solute-binding protein 9 family
CWC51_RS02240	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWC51_RS02270	COG1428	Deoxynucleoside kinase
CWC51_RS02280	COG0210	DNA helicase
CWC51_RS02285	COG1393	Belongs to the ArsC family
CWC51_RS02290	COG1393	Belongs to the ArsC family
CWC51_RS02310	COG0386	Belongs to the glutathione peroxidase family
CWC51_RS02315	COG1854	S-ribosylhomocysteine lyase activity
CWC51_RS02320	COG0626	cystathionine gamma-synthase activity
CWC51_RS02325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWC51_RS02330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWC51_RS02340	COG0019	diaminopimelate decarboxylase activity
CWC51_RS02345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CWC51_RS02355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CWC51_RS02360	COG2171	N-acyltransferase activity
CWC51_RS02365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWC51_RS02370	COG0527	aspartate kinase activity
CWC51_RS02375	COG1473	amidohydrolase
CWC51_RS02380	COG0436	Aminotransferase
CWC51_RS02385	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS02405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWC51_RS02410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWC51_RS02425	COG2207	Transcriptional regulator
CWC51_RS02430	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWC51_RS02445	COG1113	amino acid transport
CWC51_RS02450	COG1121	(ABC) transporter
CWC51_RS02455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWC51_RS02470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWC51_RS02475	COG2823	Periplasmic or secreted lipoprotein
CWC51_RS02475	COG1652	LysM domain
CWC51_RS02485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWC51_RS02490	COG0477	Major facilitator Superfamily
CWC51_RS02500	COG1438	arginine binding
CWC51_RS02515	COG1764	response to oxidative stress
CWC51_RS02520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWC51_RS02525	COG1335	isochorismatase
CWC51_RS02540	COG2135	peptidase activity
CWC51_RS02575	COG3546	catalase activity
CWC51_RS02585	COG1175	transmembrane transport
CWC51_RS02590	COG0395	ABC-type sugar transport system, permease component
CWC51_RS02630	COG0745	RESPONSE REGULATOR receiver
CWC51_RS02635	COG2205	protein histidine kinase activity
CWC51_RS02640	COG4975	Glucose uptake
CWC51_RS02645	COG0531	amino acid
CWC51_RS02650	COG3853	Toxic anion resistance protein (TelA)
CWC51_RS02670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWC51_RS02675	COG1335	isochorismatase
CWC51_RS02685	COG3590	peptidase
CWC51_RS02695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWC51_RS02700	COG1104	cysteine desulfurase activity
CWC51_RS02720	COG0482	sulfurtransferase activity
CWC51_RS02730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWC51_RS02735	COG2814	Major facilitator Superfamily
CWC51_RS02755	COG0463	Glycosyl transferase, family 2
CWC51_RS02760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWC51_RS02765	COG2855	membrane
CWC51_RS02775	COG0583	DNA-binding transcription factor activity
CWC51_RS02780	COG0772	Belongs to the SEDS family
CWC51_RS02785	COG1393	Belongs to the ArsC family
CWC51_RS02790	COG0509	glycine decarboxylation via glycine cleavage system
CWC51_RS02795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWC51_RS02800	COG2011	ABC-type metal ion transport system permease component
CWC51_RS02805	COG1464	Belongs to the NlpA lipoprotein family
CWC51_RS02815	COG0719	Fe-S assembly protein
CWC51_RS02820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWC51_RS02830	COG0719	Fe-S assembly protein
CWC51_RS02965	COG1136	(ABC) transporter
CWC51_RS02965	COG0577	efflux transmembrane transporter activity
CWC51_RS02975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWC51_RS02985	COG1597	lipid kinase activity
CWC51_RS03020	COG1733	regulation of RNA biosynthetic process
CWC51_RS03030	COG3764	Sortase (surface protein transpeptidase)
CWC51_RS03035	COG3711	transcriptional antiterminator
CWC51_RS03040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS03040	COG1263	PTS System
CWC51_RS03040	COG2190	(PTS) system
CWC51_RS03045	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS03065	COG1611	Belongs to the LOG family
CWC51_RS03075	COG1428	Deoxynucleoside kinase
CWC51_RS03085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS03090	COG1472	Belongs to the glycosyl hydrolase 3 family
CWC51_RS03100	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS03115	COG1368	sulfuric ester hydrolase activity
CWC51_RS03125	COG0105	UTP biosynthetic process
CWC51_RS03130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWC51_RS03140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWC51_RS03145	COG2011	ABC-type metal ion transport system permease component
CWC51_RS03150	COG1464	Belongs to the NlpA lipoprotein family
CWC51_RS03160	COG1757	Na H antiporter
CWC51_RS03170	COG1113	amino acid transport
CWC51_RS03180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWC51_RS03185	COG1929	Belongs to the glycerate kinase type-1 family
CWC51_RS03190	COG0488	(ABC) transporter
CWC51_RS03205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CWC51_RS03210	COG1263	PTS System
CWC51_RS03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS03215	COG1780	Probably involved in ribonucleotide reductase function
CWC51_RS03225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CWC51_RS03230	COG1131	(ABC) transporter
CWC51_RS03250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CWC51_RS03265	COG0346	lactoylglutathione lyase activity
CWC51_RS03290	COG0561	phosphatase activity
CWC51_RS03295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWC51_RS03300	COG0280	phosphate acetyltransferase
CWC51_RS03305	COG0802	atpase or kinase
CWC51_RS03310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWC51_RS03320	COG0708	Exodeoxyribonuclease III
CWC51_RS03330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWC51_RS03355	COG1053	succinate dehydrogenase
CWC51_RS03360	COG0604	alcohol dehydrogenase
CWC51_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
CWC51_RS03360	COG3321	synthase
CWC51_RS03365	COG0702	epimerase
CWC51_RS03370	COG4684	Psort location CytoplasmicMembrane, score
CWC51_RS03375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWC51_RS03380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWC51_RS03385	COG0604	alcohol dehydrogenase
CWC51_RS03395	COG3842	ATPase activity
CWC51_RS03400	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWC51_RS03405	COG1177	transmembrane transport
CWC51_RS03410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CWC51_RS03415	COG3829	transcription factor binding
CWC51_RS03430	COG3715	PTS system
CWC51_RS03435	COG3716	PTS system mannose fructose sorbose family IID component
CWC51_RS03450	COG1940	carbohydrate kinase activity
CWC51_RS03480	COG0582	viral genome integration into host DNA
CWC51_RS03485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWC51_RS03495	COG0789	Transcriptional regulator
CWC51_RS03505	COG0504	CTP synthase activity
CWC51_RS03515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWC51_RS03520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CWC51_RS03525	COG0254	rRNA binding
CWC51_RS03545	COG1349	DNA-binding transcription factor activity
CWC51_RS03555	COG2814	Major facilitator Superfamily
CWC51_RS03565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWC51_RS03585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWC51_RS03590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CWC51_RS03595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CWC51_RS03600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CWC51_RS03605	COG3870	Protein conserved in bacteria
CWC51_RS03610	COG0470	DNA polymerase III
CWC51_RS03615	COG1774	PSP1 C-terminal conserved region
CWC51_RS03620	COG4467	Involved in initiation control of chromosome replication
CWC51_RS03635	COG0602	queuosine metabolic process
CWC51_RS03640	COG1328	CTP reductase activity
CWC51_RS03645	COG1136	(ABC) transporter
CWC51_RS03650	COG0577	efflux transmembrane transporter activity
CWC51_RS03660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWC51_RS03665	COG1696	Membrane protein involved in D-alanine export
CWC51_RS03670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWC51_RS03675	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CWC51_RS03680	COG1363	Peptidase, m42
CWC51_RS03690	COG1234	tRNA 3'-trailer cleavage
CWC51_RS03695	COG0095	Lipoate-protein ligase
CWC51_RS03705	COG3328	transposase activity
CWC51_RS03725	COG3759	membrane
CWC51_RS03730	COG0659	secondary active sulfate transmembrane transporter activity
CWC51_RS03740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWC51_RS03750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWC51_RS03755	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CWC51_RS03755	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CWC51_RS03760	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS03760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS03770	COG3715	PTS system
CWC51_RS03775	COG3716	PTS system mannose fructose sorbose family IID component
CWC51_RS03785	COG2261	transglycosylase associated protein
CWC51_RS03790	COG0006	proline dipeptidase activity
CWC51_RS03795	COG1302	Protein conserved in bacteria
CWC51_RS03800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWC51_RS03805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWC51_RS03810	COG1570	exodeoxyribonuclease VII activity
CWC51_RS03815	COG1722	exodeoxyribonuclease VII activity
CWC51_RS03825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CWC51_RS03830	COG1438	arginine binding
CWC51_RS03835	COG0497	DNA recombination
CWC51_RS03870	COG0768	penicillin binding
CWC51_RS03905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWC51_RS03910	COG1799	cell septum assembly
CWC51_RS03920	COG2302	S4 RNA-binding domain
CWC51_RS03925	COG3599	regulation of cell shape
CWC51_RS03930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CWC51_RS03935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWC51_RS03955	COG0673	inositol 2-dehydrogenase activity
CWC51_RS03960	COG0513	Belongs to the DEAD box helicase family
CWC51_RS03965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CWC51_RS03965	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CWC51_RS03970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS03975	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWC51_RS03980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS04045	COG1396	sequence-specific DNA binding
CWC51_RS04095	COG3328	transposase activity
CWC51_RS04205	COG0740	serine-type endopeptidase activity
CWC51_RS04345	COG2309	aminopeptidase activity
CWC51_RS04355	COG0716	FMN binding
CWC51_RS04360	COG0024	Methionine aminopeptidase
CWC51_RS04365	COG1295	ribonuclease BN
CWC51_RS04370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWC51_RS04385	COG1215	transferase activity, transferring glycosyl groups
CWC51_RS04390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWC51_RS04400	COG1088	dTDP-glucose 4,6-dehydratase activity
CWC51_RS04405	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWC51_RS04420	COG1682	transport, permease protein
CWC51_RS04430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWC51_RS04435	COG0438	transferase activity, transferring glycosyl groups
CWC51_RS04435	COG1216	Glycosyl transferase, family 2
CWC51_RS04445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWC51_RS04450	COG1216	Glycosyl transferase, family 2
CWC51_RS04455	COG3475	LICD family
CWC51_RS04470	COG1216	Glycosyl transferase, family 2
CWC51_RS04475	COG1442	glycosyl transferase family 8
CWC51_RS04475	COG1216	Glycosyl transferase, family 2
CWC51_RS04485	COG0438	transferase activity, transferring glycosyl groups
CWC51_RS04505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWC51_RS04510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWC51_RS04520	COG4585	Histidine kinase
CWC51_RS04530	COG0569	domain protein
CWC51_RS04560	COG2246	polysaccharide biosynthetic process
CWC51_RS04565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWC51_RS04575	COG1316	TRANSCRIPTIONal
CWC51_RS04580	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CWC51_RS04585	COG3397	chitin binding
CWC51_RS04590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWC51_RS04595	COG2137	regulation of response to DNA damage stimulus
CWC51_RS04600	COG1194	a g-specific adenine glycosylase
CWC51_RS04605	COG3557	Belongs to the UPF0374 family
CWC51_RS04615	COG0628	permease
CWC51_RS04620	COG1253	flavin adenine dinucleotide binding
CWC51_RS04625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CWC51_RS04645	COG0542	response to heat
CWC51_RS04650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS04655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWC51_RS04665	COG0438	transferase activity, transferring glycosyl groups
CWC51_RS04670	COG2084	Dehydrogenase
CWC51_RS04675	COG4703	Protein of unknown function (DUF1797)
CWC51_RS04680	COG0322	excinuclease ABC activity
CWC51_RS04685	COG1846	Transcriptional regulator
CWC51_RS04690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWC51_RS04700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWC51_RS04710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWC51_RS04720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWC51_RS04725	COG0439	Biotin carboxylase
CWC51_RS04730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CWC51_RS04735	COG0825	malonyl-CoA metabolic process
CWC51_RS04740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CWC51_RS04745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWC51_RS04750	COG1534	Rna-binding protein
CWC51_RS04755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWC51_RS04760	COG1713	HD superfamily hydrolase involved in NAD metabolism
CWC51_RS04765	COG0799	negative regulation of ribosome biogenesis
CWC51_RS04770	COG2226	methyltransferase
CWC51_RS04775	COG1323	Belongs to the UPF0348 family
CWC51_RS04780	COG0217	transcriptional regulatory protein
CWC51_RS04795	COG4372	Transposase
CWC51_RS04805	COG3973	AAA domain
CWC51_RS04810	COG2217	Heavy metal translocating P-type atpase
CWC51_RS04815	COG1942	4-Oxalocrotonate Tautomerase
CWC51_RS04820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWC51_RS04825	COG1737	Transcriptional regulator
CWC51_RS04830	COG0768	penicillin binding
CWC51_RS04840	COG0561	phosphatase activity
CWC51_RS04845	COG2252	PERMEase
CWC51_RS04850	COG2814	Major facilitator Superfamily
CWC51_RS04860	COG0587	DNA-directed DNA polymerase activity
CWC51_RS04865	COG0205	6-phosphofructokinase activity
CWC51_RS04875	COG0583	DNA-binding transcription factor activity
CWC51_RS04885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CWC51_RS04890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CWC51_RS04895	COG0745	RESPONSE REGULATOR receiver
CWC51_RS04900	COG5002	protein histidine kinase activity
CWC51_RS05000	COG3711	transcriptional antiterminator
CWC51_RS05010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS05010	COG2190	(PTS) system
CWC51_RS05010	COG1263	PTS System
CWC51_RS05020	COG2190	(PTS) system
CWC51_RS05020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS05020	COG1263	PTS System
CWC51_RS05025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS05045	COG1349	DNA-binding transcription factor activity
CWC51_RS05070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CWC51_RS05075	COG3623	hexulose-6-phosphate isomerase
CWC51_RS05085	COG0456	acetyltransferase
CWC51_RS05100	COG2116	formate transmembrane transporter activity
CWC51_RS05110	COG1349	DNA-binding transcription factor activity
CWC51_RS05115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWC51_RS05120	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CWC51_RS05125	COG0246	Mannitol dehydrogenase
CWC51_RS05135	COG2213	PTS system mannitol-specific
CWC51_RS05155	COG3328	transposase activity
CWC51_RS05175	COG3775	system Galactitol-specific IIC component
CWC51_RS05190	COG0400	carboxylic ester hydrolase activity
CWC51_RS05195	COG0346	lactoylglutathione lyase activity
CWC51_RS05200	COG2188	Transcriptional regulator
CWC51_RS05205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS05210	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS05215	COG0589	response to stress
CWC51_RS05230	COG1393	Belongs to the ArsC family
CWC51_RS05245	COG0351	phosphomethylpyrimidine kinase
CWC51_RS05250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWC51_RS05255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWC51_RS05265	COG3425	synthase
CWC51_RS05270	COG0183	Belongs to the thiolase family
CWC51_RS05285	COG0656	L-ascorbic acid biosynthetic process
CWC51_RS05305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CWC51_RS05305	COG0392	lysyltransferase activity
CWC51_RS05310	COG0596	Alpha beta hydrolase
CWC51_RS05315	COG0741	lytic transglycosylase activity
CWC51_RS05325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWC51_RS05330	COG0358	DNA primase activity
CWC51_RS05335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWC51_RS05350	COG2996	Protein conserved in bacteria
CWC51_RS05355	COG0735	belongs to the Fur family
CWC51_RS05360	COG4974	Belongs to the 'phage' integrase family
CWC51_RS05370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWC51_RS05375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CWC51_RS05380	COG1187	pseudouridine synthase activity
CWC51_RS05385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CWC51_RS05390	COG1288	antiporter activity
CWC51_RS05395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWC51_RS05415	COG0514	ATP-dependent DNA helicase (RecQ)
CWC51_RS05425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWC51_RS05430	COG0539	negative regulation of cytoplasmic translation
CWC51_RS05435	COG1160	GTP binding
CWC51_RS05440	COG0776	regulation of translation
CWC51_RS05450	COG0457	Tetratricopeptide repeat
CWC51_RS05455	COG5582	Belongs to the UPF0302 family
CWC51_RS05460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWC51_RS05465	COG1694	Mazg nucleotide pyrophosphohydrolase
CWC51_RS05470	COG0617	tRNA 3'-terminal CCA addition
CWC51_RS05485	COG0025	NhaP-type Na H and K H
CWC51_RS05490	COG0488	(ABC) transporter
CWC51_RS05495	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CWC51_RS05505	COG1272	protein, Hemolysin III
CWC51_RS05510	COG1307	EDD domain protein, DegV family
CWC51_RS05515	COG2755	lipolytic protein G-D-S-L family
CWC51_RS05520	COG4698	Protein conserved in bacteria
CWC51_RS05530	COG4479	Belongs to the UPF0346 family
CWC51_RS05535	COG0681	Belongs to the peptidase S26 family
CWC51_RS05550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWC51_RS05555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWC51_RS05560	COG0758	DNA mediated transformation
CWC51_RS05565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWC51_RS05570	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CWC51_RS05575	COG4974	Belongs to the 'phage' integrase family
CWC51_RS05580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CWC51_RS05585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CWC51_RS05600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CWC51_RS05605	COG1832	CoA-binding protein
CWC51_RS05610	COG0187	DNA topoisomerase II activity
CWC51_RS05620	COG1882	Formate acetyltransferase
CWC51_RS05625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWC51_RS05630	COG1227	inorganic diphosphatase activity
CWC51_RS05650	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CWC51_RS05660	COG1073	alpha beta
CWC51_RS05665	COG1609	Transcriptional regulator
CWC51_RS05675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWC51_RS05685	COG1732	Glycine betaine
CWC51_RS05700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWC51_RS05710	COG1116	anion transmembrane transporter activity
CWC51_RS05715	COG0084	hydrolase, TatD family'
CWC51_RS05720	COG3942	CHAP domain
CWC51_RS05720	COG1388	LysM domain
CWC51_RS05740	COG3328	transposase activity
CWC51_RS05760	COG0436	Aminotransferase
CWC51_RS05785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWC51_RS05790	COG4565	transcriptional regulatory protein
CWC51_RS05795	COG3290	protein histidine kinase activity
CWC51_RS05800	COG3290	protein histidine kinase activity
CWC51_RS05810	COG2268	Band 7 protein
CWC51_RS05825	COG0673	inositol 2-dehydrogenase activity
CWC51_RS05835	COG1876	peptidase activity
CWC51_RS05840	COG1388	LysM domain
CWC51_RS05840	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWC51_RS05850	COG1653	transport
CWC51_RS05855	COG1175	transmembrane transport
CWC51_RS05860	COG0395	ABC-type sugar transport system, permease component
CWC51_RS05870	COG0673	inositol 2-dehydrogenase activity
CWC51_RS05875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWC51_RS05880	COG2233	PERMEase
CWC51_RS05885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWC51_RS05890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWC51_RS05895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWC51_RS05905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWC51_RS05910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWC51_RS05915	COG0047	phosphoribosylformylglycinamidine synthase activity
CWC51_RS05920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWC51_RS05930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CWC51_RS05935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWC51_RS05940	COG0138	bifunctional purine biosynthesis protein purh
CWC51_RS05945	COG0151	Belongs to the GarS family
CWC51_RS05950	COG4989	oxidoreductase activity
CWC51_RS05960	COG2972	Histidine kinase
CWC51_RS05970	COG4213	ABC transporter substrate-binding protein
CWC51_RS05980	COG4214	carbohydrate transport
CWC51_RS05985	COG0516	GMP reductase activity
CWC51_RS05990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWC51_RS06000	COG0022	dehydrogenase e1 component
CWC51_RS06015	COG4476	Belongs to the UPF0223 family
CWC51_RS06020	COG0483	inositol monophosphate 1-phosphatase activity
CWC51_RS06025	COG1217	gtp-binding protein TYPA
CWC51_RS06030	COG0514	ATP-dependent DNA helicase (RecQ)
CWC51_RS06035	COG4838	Belongs to the UPF0358 family
CWC51_RS06040	COG0772	Belongs to the SEDS family
CWC51_RS06045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWC51_RS06060	COG4471	UPF0298 protein
CWC51_RS06065	COG0742	ribosomal rna small subunit methyltransferase
CWC51_RS06070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWC51_RS06075	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWC51_RS06080	COG1555	photosystem II stabilization
CWC51_RS06080	COG1596	polysaccharide export
CWC51_RS06095	COG2131	deaminase
CWC51_RS06100	COG2333	competence protein COMEC
CWC51_RS06100	COG0658	competence protein
CWC51_RS06105	COG1466	dna polymerase III delta subunit
CWC51_RS06110	COG0268	Binds directly to 16S ribosomal RNA
CWC51_RS06120	COG2707	UPF0756 membrane protein
CWC51_RS06125	COG2217	Heavy metal translocating P-type atpase
CWC51_RS06130	COG1968	undecaprenyl-diphosphatase activity
CWC51_RS06150	COG1666	GTP binding
CWC51_RS06155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWC51_RS06160	COG2151	metal-sulfur cluster biosynthetic enzyme
CWC51_RS06180	COG3942	CHAP domain
CWC51_RS06180	COG1388	LysM domain
CWC51_RS06240	COG4990	cell redox homeostasis
CWC51_RS06265	COG3104	oligopeptide transport
CWC51_RS06275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CWC51_RS06280	COG1074	ATP-dependent DNA helicase activity
CWC51_RS06285	COG1733	regulation of RNA biosynthetic process
CWC51_RS06290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CWC51_RS06295	COG0072	phenylalanine-tRNA ligase activity
CWC51_RS06295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWC51_RS06305	COG1126	abc transporter atp-binding protein
CWC51_RS06310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWC51_RS06315	COG0765	amino acid transport
CWC51_RS06320	COG0765	amino acid transport
CWC51_RS06325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CWC51_RS06330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CWC51_RS06340	COG0517	IMP dehydrogenase activity
CWC51_RS06350	COG0668	transmembrane transport
CWC51_RS06355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWC51_RS06365	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWC51_RS06370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWC51_RS06400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWC51_RS06410	COG1234	tRNA 3'-trailer cleavage
CWC51_RS06415	COG0300	oxidoreductase activity
CWC51_RS06420	COG5416	Lipopolysaccharide assembly protein A domain
CWC51_RS06425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWC51_RS06425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWC51_RS06430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWC51_RS06440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CWC51_RS06460	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWC51_RS06460	COG1388	LysM domain
CWC51_RS06465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWC51_RS06470	COG0735	belongs to the Fur family
CWC51_RS06475	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS06485	COG1846	Transcriptional regulator
CWC51_RS06495	COG3935	DnaD domain protein
CWC51_RS06500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWC51_RS06510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWC51_RS06515	COG3331	DNA recombination
CWC51_RS06520	COG4474	Belongs to the UPF0398 family
CWC51_RS06525	COG3599	regulation of cell shape
CWC51_RS06535	COG0116	Belongs to the methyltransferase superfamily
CWC51_RS06540	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CWC51_RS06545	COG1418	mRNA catabolic process
CWC51_RS06550	COG0156	8-amino-7-oxononanoate synthase activity
CWC51_RS06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWC51_RS06560	COG0531	amino acid
CWC51_RS06575	COG0513	Belongs to the DEAD box helicase family
CWC51_RS06580	COG2153	protein acetylation
CWC51_RS06585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CWC51_RS06590	COG4684	Psort location CytoplasmicMembrane, score
CWC51_RS06600	COG0328	RNA-DNA hybrid ribonuclease activity
CWC51_RS06610	COG1278	Cold shock
CWC51_RS06615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CWC51_RS06630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWC51_RS06635	COG0564	pseudouridine synthase activity
CWC51_RS06645	COG2233	PERMEase
CWC51_RS06650	COG0540	Belongs to the ATCase OTCase family
CWC51_RS06655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWC51_RS06660	COG0505	Belongs to the CarA family
CWC51_RS06665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWC51_RS06670	COG0543	2 iron, 2 sulfur cluster binding
CWC51_RS06680	COG0284	orotidine-5'-phosphate decarboxylase activity
CWC51_RS06710	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CWC51_RS06730	COG4120	Belongs to the binding-protein-dependent transport system permease family
CWC51_RS06740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWC51_RS06775	COG0039	L-malate dehydrogenase activity
CWC51_RS06795	COG3037	sugar-specific permease SgaT UlaA
CWC51_RS06805	COG3711	transcriptional antiterminator
CWC51_RS06815	COG0673	inositol 2-dehydrogenase activity
CWC51_RS06865	COG0745	RESPONSE REGULATOR receiver
CWC51_RS06870	COG5002	protein histidine kinase activity
CWC51_RS06875	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CWC51_RS06900	COG0351	phosphomethylpyrimidine kinase
CWC51_RS06910	COG4475	Protein of unknown function (DUF436)
CWC51_RS06915	COG0366	Alpha amylase catalytic
CWC51_RS06930	COG1307	EDD domain protein, DegV family
CWC51_RS06935	COG2244	polysaccharide biosynthetic process
CWC51_RS06985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWC51_RS06990	COG0194	GDP metabolic process
CWC51_RS07010	COG0765	amino acid transport
CWC51_RS07015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWC51_RS07025	COG0167	dihydroorotate dehydrogenase activity
CWC51_RS07035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CWC51_RS07045	COG3833	ABC-type maltose transport systems, permease component
CWC51_RS07050	COG1175	transmembrane transport
CWC51_RS07055	COG2182	Extracellular solute-binding protein
CWC51_RS07060	COG0366	Alpha amylase catalytic
CWC51_RS07065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWC51_RS07075	COG1764	response to oxidative stress
CWC51_RS07080	COG1846	Transcriptional regulator
CWC51_RS07085	COG0628	permease
CWC51_RS07100	COG1312	Catalyzes the dehydration of D-mannonate
CWC51_RS07105	COG0246	Mannitol dehydrogenase
CWC51_RS07115	COG0450	alkyl hydroperoxide reductase
CWC51_RS07155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWC51_RS07170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CWC51_RS07185	COG0531	amino acid
CWC51_RS07190	COG0004	ammonium transporteR
CWC51_RS07195	COG2261	transglycosylase associated protein
CWC51_RS07235	COG3655	Transcriptional regulator
CWC51_RS07245	COG2261	transglycosylase associated protein
CWC51_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
CWC51_RS07280	COG1442	glycosyl transferase family 8
CWC51_RS07285	COG1442	glycosyl transferase family 8
CWC51_RS07290	COG0561	phosphatase activity
CWC51_RS07315	COG1476	TRANSCRIPTIONal
CWC51_RS07335	COG1278	Cold shock
CWC51_RS07345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS07350	COG1312	Catalyzes the dehydration of D-mannonate
CWC51_RS07370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS07375	COG3716	PTS system mannose fructose sorbose family IID component
CWC51_RS07385	COG0371	Dehydrogenase
CWC51_RS07400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CWC51_RS07405	COG0837	glucose binding
CWC51_RS07405	COG1737	Transcriptional regulator
CWC51_RS07415	COG2272	Belongs to the type-B carboxylesterase lipase family
CWC51_RS07420	COG1073	alpha beta
CWC51_RS07455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWC51_RS07475	COG3732	PTS system glucitol sorbitol-specific
CWC51_RS07480	COG3730	PTS system glucitol sorbitol-specific
CWC51_RS07490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS07490	COG3711	transcriptional antiterminator
CWC51_RS07515	COG3328	transposase activity
CWC51_RS07525	COG4974	Belongs to the 'phage' integrase family
CWC51_RS07530	COG0582	viral genome integration into host DNA
CWC51_RS07550	COG3250	beta-galactosidase activity
CWC51_RS07565	COG2211	Major facilitator Superfamily
CWC51_RS07575	COG1904	glucuronate isomerase
CWC51_RS07580	COG1312	Catalyzes the dehydration of D-mannonate
CWC51_RS07585	COG0246	Mannitol dehydrogenase
CWC51_RS07610	COG3328	transposase activity
CWC51_RS07640	COG0433	COG0433 Predicted ATPase
CWC51_RS07685	COG2946	Replication initiation factor
CWC51_RS07695	COG1674	ftsk spoiiie
CWC51_RS07735	COG0481	GTPase activity
CWC51_RS07755	COG0542	response to heat
CWC51_RS07770	COG1597	lipid kinase activity
CWC51_RS07775	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWC51_RS07780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWC51_RS07785	COG2384	SAM-dependent methyltransferase
CWC51_RS07795	COG1484	DNA-dependent DNA replication
CWC51_RS07805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWC51_RS07815	COG0237	dephospho-CoA kinase activity
CWC51_RS07820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWC51_RS07825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWC51_RS07825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWC51_RS07840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWC51_RS07845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CWC51_RS07850	COG3091	SprT-like family
CWC51_RS07855	COG2183	response to ionizing radiation
CWC51_RS07865	COG1054	Belongs to the UPF0176 family
CWC51_RS07885	COG0546	phosphoglycolate phosphatase activity
CWC51_RS07890	COG0588	phosphoglycerate mutase activity
CWC51_RS07945	COG2972	Histidine kinase
CWC51_RS07950	COG0077	Prephenate dehydratase
CWC51_RS07955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWC51_RS07960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CWC51_RS07965	COG0287	Prephenate dehydrogenase
CWC51_RS07970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWC51_RS07980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CWC51_RS07985	COG3250	beta-galactosidase activity
CWC51_RS08000	COG1609	Transcriptional regulator
CWC51_RS08010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWC51_RS08020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWC51_RS08025	COG1597	lipid kinase activity
CWC51_RS08030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWC51_RS08035	COG0154	amidase activity
CWC51_RS08040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWC51_RS08045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWC51_RS08050	COG0210	DNA helicase
CWC51_RS08060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS08060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS08060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS08065	COG1105	Belongs to the carbohydrate kinase PfkB family
CWC51_RS08070	COG1349	DNA-binding transcription factor activity
CWC51_RS08090	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CWC51_RS08095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CWC51_RS08100	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWC51_RS08110	COG1714	RDD family
CWC51_RS08125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWC51_RS08130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWC51_RS08205	COG1481	regulation of sporulation
CWC51_RS08210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CWC51_RS08215	COG1660	Displays ATPase and GTPase activities
CWC51_RS08230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWC51_RS08235	COG0556	nucleotide-excision repair
CWC51_RS08240	COG0765	amino acid transport
CWC51_RS08245	COG1126	abc transporter atp-binding protein
CWC51_RS08255	COG3835	regulator
CWC51_RS08260	COG0484	heat shock protein binding
CWC51_RS08265	COG0443	Heat shock 70 kDa protein
CWC51_RS08270	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CWC51_RS08275	COG1420	regulation of RNA biosynthetic process
CWC51_RS08280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWC51_RS08290	COG0693	protein deglycase activity
CWC51_RS08300	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWC51_RS08310	COG5646	InterPro IPR014922
CWC51_RS08325	COG4975	Glucose uptake
CWC51_RS08335	COG0196	riboflavin kinase activity
CWC51_RS08340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWC51_RS08350	COG1175	transmembrane transport
CWC51_RS08355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWC51_RS08370	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CWC51_RS08375	COG0195	Participates in both transcription termination and antitermination
CWC51_RS08380	COG0779	Required for maturation of 30S ribosomal subunits
CWC51_RS08385	COG2176	DNA-directed DNA polymerase activity
CWC51_RS08390	COG0442	prolyl-tRNA aminoacylation
CWC51_RS08395	COG0750	zinc metalloprotease
CWC51_RS08400	COG4589	Belongs to the CDS family
CWC51_RS08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWC51_RS08410	COG0233	cytoplasmic translational termination
CWC51_RS08415	COG0528	UMP kinase activity
CWC51_RS08420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWC51_RS08425	COG0052	Belongs to the universal ribosomal protein uS2 family
CWC51_RS08430	COG1438	arginine binding
CWC51_RS08440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS08445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS08450	COG0018	arginyl-trna synthetase
CWC51_RS08465	COG2235	arginine
CWC51_RS08470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWC51_RS08475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWC51_RS08480	COG0456	acetyltransferase
CWC51_RS08490	COG1214	PFAM Peptidase M22, glycoprotease
CWC51_RS08495	COG1609	Transcriptional regulator
CWC51_RS08500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWC51_RS08505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWC51_RS08520	COG3189	MarR family transcriptional regulator
CWC51_RS08525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWC51_RS08530	COG1940	carbohydrate kinase activity
CWC51_RS08545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWC51_RS08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWC51_RS08555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWC51_RS08560	COG1120	ATPase activity
CWC51_RS08575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWC51_RS08580	COG4876	unkown
CWC51_RS08590	COG0367	asparagine synthase
CWC51_RS08605	COG3328	transposase activity
CWC51_RS08620	COG1309	transcriptional regulator
CWC51_RS08640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWC51_RS08655	COG0584	glycerophosphoryl diester phosphodiesterase
CWC51_RS08695	COG0166	Belongs to the GPI family
CWC51_RS08700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWC51_RS08705	COG2081	HI0933 family
CWC51_RS08710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWC51_RS08715	COG0710	3-dehydroquinate dehydratase activity
CWC51_RS08720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWC51_RS08725	COG1368	sulfuric ester hydrolase activity
CWC51_RS08745	COG5002	protein histidine kinase activity
CWC51_RS08745	COG3850	Histidine kinase
CWC51_RS08750	COG0745	RESPONSE REGULATOR receiver
CWC51_RS08795	COG3328	transposase activity
CWC51_RS08810	COG1956	GAF domain-containing protein
CWC51_RS08815	COG3527	Alpha-acetolactate decarboxylase
CWC51_RS08820	COG0028	Belongs to the TPP enzyme family
CWC51_RS08830	COG0395	ABC-type sugar transport system, permease component
CWC51_RS08840	COG0583	DNA-binding transcription factor activity
CWC51_RS08845	COG0789	Transcriptional regulator
CWC51_RS08850	COG2814	Major facilitator Superfamily
CWC51_RS08905	COG4974	Belongs to the 'phage' integrase family
CWC51_RS08930	COG1475	DNA binding
CWC51_RS08935	COG3969	phosphoadenosine phosphosulfate
CWC51_RS08940	COG2801	Transposase and inactivated derivatives
CWC51_RS08970	COG3716	PTS system mannose fructose sorbose family IID component
CWC51_RS08980	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS08995	COG1105	Belongs to the carbohydrate kinase PfkB family
CWC51_RS09000	COG3684	Belongs to the aldolase LacD family
CWC51_RS09005	COG2222	sugar isomerase
CWC51_RS09010	COG2188	Transcriptional regulator
CWC51_RS09075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CWC51_RS09190	COG3547	Transposase (IS116 IS110 IS902 family)
CWC51_RS09295	COG3177	Filamentation induced by cAMP protein fic
CWC51_RS09335	COG0741	lytic transglycosylase activity
CWC51_RS09335	COG1196	nuclear chromosome segregation
CWC51_RS09335	COG0739	heme binding
CWC51_RS09500	COG0335	large ribosomal subunit rRNA binding
CWC51_RS09505	COG0336	Belongs to the RNA methyltransferase TrmD family
CWC51_RS09510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CWC51_RS09520	COG1837	Belongs to the UPF0109 family
CWC51_RS09525	COG0228	four-way junction DNA binding
CWC51_RS09530	COG0431	NADPH-dependent FMN reductase
CWC51_RS09535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWC51_RS09540	COG0519	Catalyzes the synthesis of GMP from XMP
CWC51_RS09545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWC51_RS09550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CWC51_RS09560	COG0745	RESPONSE REGULATOR receiver
CWC51_RS09565	COG5002	protein histidine kinase activity
CWC51_RS09570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWC51_RS09580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWC51_RS09605	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CWC51_RS09630	COG3328	transposase activity
CWC51_RS09670	COG0714	Associated with various cellular activities
CWC51_RS09690	COG2217	Heavy metal translocating P-type atpase
CWC51_RS09695	COG2217	Heavy metal translocating P-type atpase
CWC51_RS09700	COG2608	mercury ion transmembrane transporter activity
CWC51_RS09705	COG3682	Transcriptional regulator
CWC51_RS09715	COG0531	amino acid
CWC51_RS09720	COG2217	Heavy metal translocating P-type atpase
CWC51_RS09740	COG0017	Asparaginyl-tRNA synthetase
CWC51_RS09745	COG0436	Aminotransferase
CWC51_RS09755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWC51_RS09755	COG1199	ATP-dependent helicase activity
CWC51_RS09760	COG1278	Cold shock
CWC51_RS09775	COG1686	Belongs to the peptidase S11 family
CWC51_RS09785	COG0038	chloride channel
CWC51_RS09810	COG1254	Belongs to the acylphosphatase family
CWC51_RS09815	COG0706	membrane insertase activity
CWC51_RS09820	COG3684	Belongs to the aldolase LacD family
CWC51_RS09825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWC51_RS09825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS09825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS09830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS09830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS09830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS09835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWC51_RS09840	COG1105	Belongs to the carbohydrate kinase PfkB family
CWC51_RS09890	COG0438	transferase activity, transferring glycosyl groups
CWC51_RS09900	COG1216	Glycosyl transferase, family 2
CWC51_RS09900	COG0463	Glycosyl transferase, family 2
CWC51_RS09905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWC51_RS09910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWC51_RS09920	COG4464	protein tyrosine phosphatase activity
CWC51_RS09925	COG0489	protein tyrosine kinase activity
CWC51_RS09930	COG3944	biosynthesis protein
CWC51_RS09935	COG1316	TRANSCRIPTIONal
CWC51_RS09945	COG3328	transposase activity
CWC51_RS09955	COG0751	glycine-tRNA ligase activity
CWC51_RS09960	COG0752	glycyl-tRNA synthetase alpha subunit
CWC51_RS09965	COG1381	Involved in DNA repair and RecF pathway recombination
CWC51_RS09970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWC51_RS09975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CWC51_RS09980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CWC51_RS09990	COG1702	phosphate starvation-inducible protein PhoH
CWC51_RS09995	COG1114	Component of the transport system for branched-chain amino acids
CWC51_RS10005	COG1610	YqeY-like protein
CWC51_RS10010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CWC51_RS10015	COG0735	belongs to the Fur family
CWC51_RS10020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CWC51_RS10025	COG0640	Transcriptional regulator
CWC51_RS10030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWC51_RS10035	COG0492	ferredoxin-NADP+ reductase activity
CWC51_RS10040	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS10045	COG1486	melibiose metabolic process
CWC51_RS10050	COG1737	Transcriptional regulator
CWC51_RS10055	COG2190	(PTS) system
CWC51_RS10055	COG1263	PTS System
CWC51_RS10055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS10060	COG3711	transcriptional antiterminator
CWC51_RS10065	COG1132	(ABC) transporter
CWC51_RS10070	COG1132	(ABC) transporter
CWC51_RS10075	COG3763	UPF0154 protein
CWC51_RS10080	COG1914	H( )-stimulated, divalent metal cation uptake system
CWC51_RS10090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CWC51_RS10100	COG1609	Transcriptional regulator
CWC51_RS10110	COG4980	gas vesicle protein
CWC51_RS10120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWC51_RS10125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWC51_RS10130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWC51_RS10135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CWC51_RS10140	COG1950	PFAM Membrane protein of
CWC51_RS10165	COG0704	Plays a role in the regulation of phosphate uptake
CWC51_RS10170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWC51_RS10175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWC51_RS10180	COG0581	inorganic phosphate transmembrane transporter activity
CWC51_RS10185	COG0573	inorganic phosphate transmembrane transporter activity
CWC51_RS10190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWC51_RS10195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWC51_RS10200	COG2177	Part of the ABC transporter FtsEX involved in
CWC51_RS10205	COG2884	Cell division ATP-binding protein ftsE
CWC51_RS10215	COG0653	protein targeting
CWC51_RS10230	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CWC51_RS10235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS10245	COG1739	Uncharacterized protein family UPF0029
CWC51_RS10250	COG2188	Transcriptional regulator
CWC51_RS10275	COG1940	carbohydrate kinase activity
CWC51_RS10295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWC51_RS10305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWC51_RS10310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CWC51_RS10315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CWC51_RS10320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CWC51_RS10325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWC51_RS10330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CWC51_RS10335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWC51_RS10340	COG0356	it plays a direct role in the translocation of protons across the membrane
CWC51_RS10355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWC51_RS10360	COG2388	GCN5-related N-acetyl-transferase
CWC51_RS10370	COG1957	nucleoside hydrolase
CWC51_RS10395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWC51_RS10405	COG0149	triose-phosphate isomerase activity
CWC51_RS10410	COG0126	phosphoglycerate kinase activity
CWC51_RS10420	COG2390	Transcriptional regulator
CWC51_RS10425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWC51_RS10445	COG1595	DNA-templated transcription, initiation
CWC51_RS10460	COG0095	Lipoate-protein ligase
CWC51_RS10465	COG1078	dGTPase activity
CWC51_RS10470	COG0561	phosphatase activity
CWC51_RS10475	COG0494	nUDIX hydrolase
CWC51_RS10480	COG0346	lactoylglutathione lyase activity
CWC51_RS10490	COG2423	ornithine cyclodeaminase activity
CWC51_RS10495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWC51_RS10500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWC51_RS10505	COG1394	ATPase activity, coupled to movement of substances
CWC51_RS10510	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CWC51_RS10515	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CWC51_RS10520	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
CWC51_RS10525	COG1527	subunit (C
CWC51_RS10530	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CWC51_RS10535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWC51_RS10540	COG1269	ATP hydrolysis coupled proton transport
CWC51_RS10550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWC51_RS10555	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CWC51_RS10565	COG4152	abc transporter atp-binding protein
CWC51_RS10570	COG0322	excinuclease ABC activity
CWC51_RS10575	COG3118	belongs to the thioredoxin family
CWC51_RS10580	COG1193	negative regulation of DNA recombination
CWC51_RS10595	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWC51_RS10610	COG1136	(ABC) transporter
CWC51_RS10620	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS10650	COG1304	FMN binding
CWC51_RS10660	COG0281	malic enzyme
CWC51_RS10700	COG4695	Portal protein
CWC51_RS10780	COG4974	Belongs to the 'phage' integrase family
CWC51_RS10785	COG3906	Belongs to the UPF0473 family
CWC51_RS10790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CWC51_RS10795	COG4472	Bacterial protein of unknown function (DUF965)
CWC51_RS10825	COG4555	ABC transporter
CWC51_RS10835	COG3689	TIGRFAM TIGR03943 family protein
CWC51_RS10840	COG0701	Predicted permease
CWC51_RS10845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWC51_RS10850	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CWC51_RS10855	COG0488	(ABC) transporter
CWC51_RS10860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWC51_RS10875	COG0395	ABC-type sugar transport system, permease component
CWC51_RS10895	COG0662	Cupin 2, conserved barrel domain protein
CWC51_RS10895	COG2207	Transcriptional regulator
CWC51_RS10900	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWC51_RS10910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWC51_RS10915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CWC51_RS10920	COG0584	glycerophosphoryl diester phosphodiesterase
CWC51_RS10930	COG0740	serine-type endopeptidase activity
CWC51_RS10935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CWC51_RS10945	COG1132	(ABC) transporter
CWC51_RS10955	COG5503	Protein of unknown function (DUF1447)
CWC51_RS10970	COG1278	Cold shock
CWC51_RS10975	COG2003	Belongs to the UPF0758 family
CWC51_RS10980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS10985	COG0285	dihydrofolate synthase activity
CWC51_RS10990	COG0525	valine-tRNA ligase activity
CWC51_RS10995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CWC51_RS11000	COG0301	tRNA thio-modification
CWC51_RS11005	COG1104	cysteine desulfurase activity
CWC51_RS11010	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CWC51_RS11020	COG0561	phosphatase activity
CWC51_RS11025	COG1801	Protein of unknown function DUF72
CWC51_RS11045	COG3579	cysteine-type endopeptidase activity
CWC51_RS11095	COG4372	Transposase
CWC51_RS11130	COG1098	S1 RNA binding domain
CWC51_RS11135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWC51_RS11145	COG0492	ferredoxin-NADP+ reductase activity
CWC51_RS11150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWC51_RS11165	COG4470	Protein conserved in bacteria
CWC51_RS11170	COG0737	Belongs to the 5'-nucleotidase family
CWC51_RS11180	COG0590	tRNA wobble adenosine to inosine editing
CWC51_RS11185	COG2508	Transcriptional regulator
CWC51_RS11195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWC51_RS11195	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CWC51_RS11210	COG2738	Putative neutral zinc metallopeptidase
CWC51_RS11215	COG2824	Alkylphosphonate utilization operon protein PhnA
CWC51_RS11220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWC51_RS11225	COG4109	DRTGG domain
CWC51_RS11230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CWC51_RS11255	COG0577	efflux transmembrane transporter activity
CWC51_RS11260	COG1136	(ABC) transporter
CWC51_RS11270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CWC51_RS11275	COG1288	antiporter activity
CWC51_RS11280	COG4821	SIS domain
CWC51_RS11300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWC51_RS11305	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CWC51_RS11310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWC51_RS11315	COG3716	PTS system mannose fructose sorbose family IID component
CWC51_RS11320	COG3715	PTS system
CWC51_RS11350	COG1132	(ABC) transporter
CWC51_RS11355	COG1132	(ABC) transporter
CWC51_RS11365	COG1803	Methylglyoxal synthase
CWC51_RS11370	COG3842	ATPase activity
CWC51_RS11380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWC51_RS11385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CWC51_RS11390	COG0084	hydrolase, TatD family'
CWC51_RS11395	COG0531	amino acid
CWC51_RS11405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWC51_RS11405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWC51_RS11420	COG0675	Transposase, IS605 OrfB family
CWC51_RS11425	COG4608	Belongs to the ABC transporter superfamily
CWC51_RS11430	COG0444	Belongs to the ABC transporter superfamily
CWC51_RS11435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWC51_RS11440	COG0601	transmembrane transport
CWC51_RS11450	COG4166	transmembrane transport
CWC51_RS11465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CWC51_RS11470	COG1674	ftsk spoiiie
CWC51_RS11470	COG1280	lysine exporter protein (LysE YggA)
CWC51_RS11475	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWC51_RS11485	COG1126	abc transporter atp-binding protein
CWC51_RS11490	COG0765	amino acid transport
CWC51_RS11545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWC51_RS11555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CWC51_RS11560	COG0009	L-threonylcarbamoyladenylate synthase
CWC51_RS11570	COG2890	protein-(glutamine-N5) methyltransferase activity
CWC51_RS11575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWC51_RS11580	COG1435	thymidine kinase activity
CWC51_RS11590	COG2226	methyltransferase
CWC51_RS11595	COG0681	Belongs to the peptidase S26 family
CWC51_RS11615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWC51_RS11620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWC51_RS11625	COG3442	glutamine amidotransferase
CWC51_RS11630	COG0246	Mannitol dehydrogenase
CWC51_RS11635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS11640	COG2213	PTS system mannitol-specific
CWC51_RS11645	COG1131	(ABC) transporter
CWC51_RS11655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS11660	COG3711	transcriptional antiterminator
CWC51_RS11665	COG2213	PTS system mannitol-specific
CWC51_RS11670	COG1482	cell wall glycoprotein biosynthetic process
CWC51_RS11685	COG1132	(ABC) transporter
CWC51_RS11705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CWC51_RS11710	COG0628	permease
CWC51_RS11720	COG2706	6-phosphogluconolactonase activity
CWC51_RS11735	COG1368	sulfuric ester hydrolase activity
CWC51_RS11745	COG2160	L-arabinose isomerase activity
CWC51_RS11750	COG0235	Class ii aldolase
CWC51_RS11770	COG3940	Belongs to the glycosyl hydrolase 43 family
CWC51_RS11775	COG3534	alpha-L-arabinofuranosidase
CWC51_RS11785	COG0395	ABC-type sugar transport system, permease component
CWC51_RS11790	COG1175	transmembrane transport
CWC51_RS11810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CWC51_RS11815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWC51_RS11825	COG0789	Transcriptional regulator
CWC51_RS11830	COG1609	Transcriptional regulator
CWC51_RS11845	COG0459	protein refolding
CWC51_RS11850	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWC51_RS11860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS11865	COG2910	NAD(P)H-binding
CWC51_RS11870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWC51_RS11885	COG5002	protein histidine kinase activity
CWC51_RS11890	COG0745	RESPONSE REGULATOR receiver
CWC51_RS11895	COG1307	EDD domain protein, DegV family
CWC51_RS11940	COG4175	Glycine betaine
CWC51_RS11940	COG3448	diguanylate cyclase activity
CWC51_RS11965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWC51_RS11970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWC51_RS11980	COG0628	permease
CWC51_RS11985	COG1285	pathogenesis
CWC51_RS11990	COG0363	glucosamine-6-phosphate deaminase activity
CWC51_RS11995	COG0488	(ABC) transporter
CWC51_RS12010	COG2814	Major facilitator Superfamily
CWC51_RS12020	COG0222	ribosome binding
CWC51_RS12025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWC51_RS12030	COG0081	regulation of translation
CWC51_RS12035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CWC51_RS12040	COG1760	l-serine dehydratase
CWC51_RS12045	COG1760	l-serine dehydratase
CWC51_RS12050	COG1304	FMN binding
CWC51_RS12055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CWC51_RS12060	COG0250	Participates in transcription elongation, termination and antitermination
CWC51_RS12065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWC51_RS12070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWC51_RS12085	COG1597	lipid kinase activity
CWC51_RS12100	COG1131	(ABC) transporter
CWC51_RS12105	COG4585	Histidine kinase
CWC51_RS12110	COG2197	response regulator
CWC51_RS12120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWC51_RS12130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CWC51_RS12135	COG2226	methyltransferase
CWC51_RS12140	COG3142	Participates in the control of copper homeostasis
CWC51_RS12145	COG2239	Acts as a magnesium transporter
CWC51_RS12150	COG0564	pseudouridine synthase activity
CWC51_RS12155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWC51_RS12160	COG2357	RelA SpoT domain protein
CWC51_RS12165	COG4116	CYTH
CWC51_RS12175	COG3328	transposase activity
CWC51_RS12195	COG4862	establishment of competence for transformation
CWC51_RS12200	COG1393	Belongs to the ArsC family
CWC51_RS12215	COG0419	ATPase involved in DNA repair
CWC51_RS12220	COG0420	3'-5' exonuclease activity
CWC51_RS12225	COG0204	Acyl-transferase
CWC51_RS12230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWC51_RS12235	COG2827	Endonuclease containing a URI domain
CWC51_RS12240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWC51_RS12240	COG2755	lipolytic protein G-D-S-L family
CWC51_RS12245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWC51_RS12250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWC51_RS12255	COG0124	histidyl-tRNA synthetase
CWC51_RS12260	COG0667	Aldo Keto reductase
CWC51_RS12265	COG2124	cytochrome p450
CWC51_RS12270	COG1490	D-aminoacyl-tRNA deacylase activity
CWC51_RS12275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWC51_RS12280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWC51_RS12285	COG2264	protein methyltransferase activity
CWC51_RS12295	COG2094	Belongs to the DNA glycosylase MPG family
CWC51_RS12300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWC51_RS12315	COG0589	response to stress
CWC51_RS12325	COG0488	(ABC) transporter
CWC51_RS12330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CWC51_RS12335	COG0827	DNA restriction-modification system
CWC51_RS12360	COG4537	Required for transformation and DNA binding
CWC51_RS12365	COG1459	type II secretion system
CWC51_RS12370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWC51_RS12375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CWC51_RS12380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CWC51_RS12390	COG4473	ABC transporter
CWC51_RS12395	COG1131	(ABC) transporter
CWC51_RS12400	COG0537	adenosine 5'-monophosphoramidase activity
CWC51_RS12410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWC51_RS12415	COG3481	metal-dependent phosphohydrolase, HD sub domain
CWC51_RS12420	COG4717	serine-type aminopeptidase activity
CWC51_RS12425	COG0420	3'-5' exonuclease activity
CWC51_RS12430	COG0561	phosphatase activity
CWC51_RS12455	COG2211	Major facilitator Superfamily
CWC51_RS12460	COG3507	Belongs to the glycosyl hydrolase 43 family
CWC51_RS12475	COG1073	alpha beta
CWC51_RS12485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWC51_RS12490	COG1653	transport
CWC51_RS12500	COG4209	transmembrane transport
CWC51_RS12505	COG0395	ABC-type sugar transport system, permease component
CWC51_RS12510	COG2207	Transcriptional regulator
CWC51_RS12515	COG1609	Transcriptional regulator
CWC51_RS12520	COG0246	Mannitol dehydrogenase
CWC51_RS12525	COG2721	sulfolactate sulfo-lyase activity
CWC51_RS12530	COG1904	glucuronate isomerase
CWC51_RS12535	COG2755	lipolytic protein G-D-S-L family
CWC51_RS12545	COG1132	(ABC) transporter
CWC51_RS12550	COG3679	Belongs to the UPF0342 family
CWC51_RS12555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWC51_RS12560	COG0564	pseudouridine synthase activity
CWC51_RS12565	COG1940	carbohydrate kinase activity
CWC51_RS12570	COG0383	alpha-mannosidase activity
CWC51_RS12590	COG2207	Transcriptional regulator
CWC51_RS12590	COG4753	response regulator
CWC51_RS12595	COG2972	Histidine kinase
CWC51_RS12605	COG1653	transport
CWC51_RS12610	COG0395	ABC-type sugar transport system, permease component
CWC51_RS12630	COG1187	pseudouridine synthase activity
CWC51_RS12635	COG2244	polysaccharide biosynthetic process
CWC51_RS12645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWC51_RS12650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS12665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWC51_RS12665	COG3711	transcriptional antiterminator
CWC51_RS12710	COG4978	Transcriptional regulator
CWC51_RS12710	COG0789	Transcriptional regulator
CWC51_RS12720	COG1132	(ABC) transporter
CWC51_RS12730	COG0495	leucyl-tRNA aminoacylation
CWC51_RS12735	COG1388	LysM domain
CWC51_RS12735	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWC51_RS12740	COG0671	phosphoesterase, PA-phosphatase related
CWC51_RS12745	COG1242	4 iron, 4 sulfur cluster binding
CWC51_RS12750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CWC51_RS12800	COG0582	viral genome integration into host DNA
CWC51_RS12805	COG3328	transposase activity
CWC51_RS12820	COG1132	(ABC) transporter
CWC51_RS12825	COG1132	(ABC) transporter
CWC51_RS12840	COG0477	Major facilitator Superfamily
CWC51_RS12845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWC51_RS13000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWC51_RS13005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWC51_RS13010	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CWC51_RS13020	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWC51_RS13025	COG0037	tRNA processing
CWC51_RS13030	COG1098	S1 RNA binding domain
CWC51_RS13040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWC51_RS13045	COG2244	polysaccharide biosynthetic process
CWC51_RS13050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWC51_RS13055	COG0193	aminoacyl-tRNA hydrolase activity
CWC51_RS13060	COG0039	L-malate dehydrogenase activity
CWC51_RS13070	COG0217	transcriptional regulatory protein
CWC51_RS13095	COG1792	Involved in formation and maintenance of cell shape
CWC51_RS13105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWC51_RS13115	COG1162	GTPase activity
CWC51_RS13120	COG0515	serine threonine protein kinase
CWC51_RS13120	COG2815	serine threonine protein kinase
CWC51_RS13125	COG0631	protein serine/threonine phosphatase activity
CWC51_RS13130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWC51_RS13130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWC51_RS13135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWC51_RS13140	COG0242	peptide deformylase activity
CWC51_RS13145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWC51_RS13150	COG1758	RNA polymerase activity
CWC51_RS13155	COG0194	GDP metabolic process
CWC51_RS13165	COG1561	YicC-like family, N-terminal region
CWC51_RS13175	COG1752	Esterase of the alpha-beta hydrolase superfamily
CWC51_RS13190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWC51_RS13195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWC51_RS13200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWC51_RS13205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWC51_RS13210	COG1121	(ABC) transporter
CWC51_RS13215	COG3443	Belongs to the bacterial solute-binding protein 9 family
CWC51_RS13215	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWC51_RS13220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CWC51_RS13225	COG0392	lysyltransferase activity
CWC51_RS13225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CWC51_RS13230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWC51_RS13235	COG1418	mRNA catabolic process
CWC51_RS13240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWC51_RS13245	COG1058	Belongs to the CinA family
CWC51_RS13245	COG1546	Belongs to the CinA family
CWC51_RS13250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWC51_RS13255	COG1426	Protein conserved in bacteria
CWC51_RS13260	COG0612	Peptidase, M16
CWC51_RS13265	COG0612	Peptidase, M16
CWC51_RS13270	COG1970	mechanosensitive ion channel activity
CWC51_RS13275	COG2153	protein acetylation
CWC51_RS13280	COG4466	Protein conserved in bacteria
CWC51_RS13290	COG3688	RNA-binding protein containing a PIN domain
CWC51_RS13295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWC51_RS13300	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CWC51_RS13305	COG0215	cysteine-tRNA ligase activity
CWC51_RS13310	COG1045	serine acetyltransferase
CWC51_RS13315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWC51_RS13320	COG4956	integral membrane protein (PIN domain superfamily)
CWC51_RS13330	COG0756	dUTP diphosphatase activity
CWC51_RS13335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWC51_RS13340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CWC51_RS13355	COG2814	Major facilitator Superfamily
CWC51_RS13375	COG0778	Nitroreductase
CWC51_RS13385	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWC51_RS13385	COG1388	LysM domain
CWC51_RS13390	COG4221	oxidoreductase activity
CWC51_RS13400	COG0583	DNA-binding transcription factor activity
CWC51_RS13405	COG3711	transcriptional antiterminator
CWC51_RS13410	COG1263	PTS System
CWC51_RS13410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS13410	COG2190	(PTS) system
CWC51_RS13415	COG0702	epimerase
CWC51_RS13430	COG2207	Transcriptional regulator
CWC51_RS13430	COG3708	Transcriptional regulator
CWC51_RS13445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CWC51_RS13455	COG0604	alcohol dehydrogenase
CWC51_RS13460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWC51_RS13465	COG0842	Transport permease protein
CWC51_RS13470	COG1131	(ABC) transporter
CWC51_RS13480	COG2205	protein histidine kinase activity
CWC51_RS13485	COG0745	RESPONSE REGULATOR receiver
CWC51_RS13505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CWC51_RS13510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWC51_RS13515	COG0783	Belongs to the Dps family
CWC51_RS13520	COG1070	Carbohydrate kinase
CWC51_RS13525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CWC51_RS13530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWC51_RS13535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWC51_RS13555	COG1082	Xylose isomerase domain protein TIM barrel
CWC51_RS13560	COG1063	alcohol dehydrogenase
CWC51_RS13565	COG0395	ABC-type sugar transport system, permease component
CWC51_RS13570	COG1175	transmembrane transport
CWC51_RS13575	COG1653	transport
CWC51_RS13580	COG0366	Alpha amylase catalytic
CWC51_RS13585	COG1609	Transcriptional regulator
CWC51_RS13590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWC51_RS13595	COG0085	RNA polymerase activity
CWC51_RS13605	COG4120	Belongs to the binding-protein-dependent transport system permease family
CWC51_RS13615	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CWC51_RS13615	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CWC51_RS13630	COG0142	geranyltranstransferase activity
CWC51_RS13650	COG4939	FMN-binding domain protein
CWC51_RS13665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWC51_RS13670	COG0826	peptidase U32
CWC51_RS13675	COG0826	peptidase U32
CWC51_RS13680	COG0542	response to heat
CWC51_RS13685	COG4463	regulation of RNA biosynthetic process
CWC51_RS13765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CWC51_RS13770	COG0516	GMP reductase activity
CWC51_RS13770	COG0517	IMP dehydrogenase activity
CWC51_RS13780	COG0012	GTP binding
CWC51_RS13785	COG4481	Protein conserved in bacteria
CWC51_RS13790	COG1475	DNA binding
CWC51_RS13795	COG1192	Involved in chromosome partitioning
CWC51_RS13800	COG0357	Ribosomal RNA small subunit methyltransferase G
CWC51_RS13805	COG0445	tRNA wobble uridine modification
CWC51_RS13810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWC51_RS13820	COG1847	R3H domain protein
CWC51_RS13825	COG0706	membrane insertase activity
CWC51_RS13830	COG0594	ribonuclease P activity
CWC51_RS13835	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CWC51_RS13890	COG0629	single-stranded DNA binding
CWC51_RS13935	COG4115	mRNA cleavage
CWC51_RS13985	COG0395	ABC-type sugar transport system, permease component
CWC51_RS13995	COG1940	carbohydrate kinase activity
CWC51_RS14090	COG3328	transposase activity
CWC51_RS14095	COG0582	viral genome integration into host DNA
CWC51_RS14105	COG0346	lactoylglutathione lyase activity
CWC51_RS14115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWC51_RS14120	COG1609	Transcriptional regulator
CWC51_RS14135	COG0395	ABC-type sugar transport system, permease component
CWC51_RS14140	COG1486	melibiose metabolic process
CWC51_RS14145	COG1653	transport
CWC51_RS14150	COG1175	transmembrane transport
CWC51_RS14155	COG0395	ABC-type sugar transport system, permease component
CWC51_RS14165	COG0366	Alpha amylase catalytic
CWC51_RS14170	COG0366	Alpha amylase catalytic
CWC51_RS14190	COG0582	viral genome integration into host DNA
CWC51_RS14195	COG4974	Belongs to the 'phage' integrase family
CWC51_RS14240	COG1609	Transcriptional regulator
CWC51_RS14245	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWC51_RS14250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS14260	COG2723	6-phospho-beta-galactosidase activity
CWC51_RS14280	COG1609	Transcriptional regulator
CWC51_RS14285	COG1621	beta-fructofuranosidase activity
CWC51_RS14290	COG2190	(PTS) system
CWC51_RS14290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWC51_RS14290	COG1263	PTS System
CWC51_RS14295	COG3328	transposase activity
CWC51_RS14300	COG1940	carbohydrate kinase activity
CWC51_RS14335	COG4372	Transposase
CWC51_RS14345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWC51_RS14360	COG3775	system Galactitol-specific IIC component
CWC51_RS14380	COG3328	transposase activity
CWC51_RS14470	COG3328	transposase activity
CWC51_RS14495	COG4974	Belongs to the 'phage' integrase family
CWC51_RS14665	COG4372	Transposase
CWC51_RS14690	COG0456	acetyltransferase
CWC51_RS14720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWC51_RS14735	COG3409	Peptidoglycan-binding domain 1 protein
CWC51_RS14760	COG5002	protein histidine kinase activity
CWC51_RS14775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWC51_RS14790	COG3842	ATPase activity
CWC51_RS14800	COG0395	ABC-type sugar transport system, permease component
CWC51_RS14815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CWC51_RS14835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWC51_RS14850	COG1136	(ABC) transporter
CWC51_RS14870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWC51_RS14935	COG2207	Transcriptional regulator
CWC51_RS15020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWC51_RS15035	COG0488	(ABC) transporter
CWC51_RS15205	COG1674	ftsk spoiiie
CWC51_RS15240	COG3764	Sortase (surface protein transpeptidase)
CWC51_RS15315	COG0551	DNA topoisomerase type I activity
CWC51_RS15315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWC51_RS15500	COG0542	response to heat
CWC51_RS15545	COG1598	PFAM Uncharacterised protein family UPF0150
CWC51_RS15615	COG1609	Transcriptional regulator
CWC51_RS15620	COG1940	carbohydrate kinase activity
CWC51_RS15735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWC51_RS15745	COG1737	Transcriptional regulator
CWC51_RS15760	COG5290	Psort location Cytoplasmic, score
CWC51_RS15770	COG5290	Psort location Cytoplasmic, score
CWC51_RS15785	COG3250	beta-galactosidase activity
CWC51_RS15805	COG4209	transmembrane transport
CWC51_RS15810	COG0395	ABC-type sugar transport system, permease component
CWC51_RS15865	COG2226	methyltransferase
CWC51_RS15875	COG0456	acetyltransferase
CWC51_RS15885	COG2378	regulation of single-species biofilm formation
CWC51_RS16025	COG4115	mRNA cleavage
CWC51_RS16050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWC51_RS16070	COG1192	Involved in chromosome partitioning
CWC51_RS16215	COG0772	Belongs to the SEDS family