locus-tag	class	description
FHJ99_RS00005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS00015	COG3684	Belongs to the aldolase LacD family
FHJ99_RS00020	COG2222	sugar isomerase
FHJ99_RS00025	COG2188	Transcriptional regulator
FHJ99_RS00040	COG3842	ATPase activity
FHJ99_RS00050	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS00065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FHJ99_RS00145	COG1136	(ABC) transporter
FHJ99_RS00170	COG5002	protein histidine kinase activity
FHJ99_RS00180	COG1136	(ABC) transporter
FHJ99_RS00185	COG3328	transposase activity
FHJ99_RS00195	COG2188	Transcriptional regulator
FHJ99_RS00200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS00205	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS00210	COG3715	PTS system
FHJ99_RS00220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS00225	COG2222	sugar isomerase
FHJ99_RS00300	COG0531	amino acid
FHJ99_RS00310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS00310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS00320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FHJ99_RS00325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHJ99_RS00330	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS00335	COG3715	PTS system
FHJ99_RS00360	COG1132	(ABC) transporter
FHJ99_RS00365	COG1132	(ABC) transporter
FHJ99_RS00400	COG0084	hydrolase, TatD family'
FHJ99_RS00420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FHJ99_RS00425	COG1674	ftsk spoiiie
FHJ99_RS00425	COG1280	lysine exporter protein (LysE YggA)
FHJ99_RS00430	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS00440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHJ99_RS00445	COG1126	abc transporter atp-binding protein
FHJ99_RS00450	COG0765	amino acid transport
FHJ99_RS00490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FHJ99_RS00500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FHJ99_RS00505	COG0009	L-threonylcarbamoyladenylate synthase
FHJ99_RS00515	COG2890	protein-(glutamine-N5) methyltransferase activity
FHJ99_RS00520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FHJ99_RS00525	COG1435	thymidine kinase activity
FHJ99_RS00535	COG2226	methyltransferase
FHJ99_RS00540	COG0681	Belongs to the peptidase S26 family
FHJ99_RS00560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHJ99_RS00565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHJ99_RS00570	COG3442	glutamine amidotransferase
FHJ99_RS00575	COG0246	Mannitol dehydrogenase
FHJ99_RS00580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS00585	COG2213	PTS system mannitol-specific
FHJ99_RS00590	COG1131	(ABC) transporter
FHJ99_RS00600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS00605	COG3711	transcriptional antiterminator
FHJ99_RS00610	COG2213	PTS system mannitol-specific
FHJ99_RS00615	COG1482	cell wall glycoprotein biosynthetic process
FHJ99_RS00640	COG1132	(ABC) transporter
FHJ99_RS00660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FHJ99_RS00665	COG0628	permease
FHJ99_RS00675	COG2706	6-phosphogluconolactonase activity
FHJ99_RS00685	COG1368	sulfuric ester hydrolase activity
FHJ99_RS00695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHJ99_RS00700	COG2160	L-arabinose isomerase activity
FHJ99_RS00705	COG0235	Class ii aldolase
FHJ99_RS00725	COG3940	Belongs to the glycosyl hydrolase 43 family
FHJ99_RS00730	COG3534	alpha-L-arabinofuranosidase
FHJ99_RS00740	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS00745	COG1175	transmembrane transport
FHJ99_RS00765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FHJ99_RS00770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHJ99_RS00785	COG0789	Transcriptional regulator
FHJ99_RS00790	COG1609	Transcriptional regulator
FHJ99_RS00800	COG0459	protein refolding
FHJ99_RS00805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHJ99_RS00815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS00820	COG2910	NAD(P)H-binding
FHJ99_RS00825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FHJ99_RS00840	COG5002	protein histidine kinase activity
FHJ99_RS00845	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS00850	COG1307	EDD domain protein, DegV family
FHJ99_RS00890	COG3448	diguanylate cyclase activity
FHJ99_RS00890	COG4175	Glycine betaine
FHJ99_RS00920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FHJ99_RS00925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHJ99_RS00935	COG0628	permease
FHJ99_RS00940	COG1285	pathogenesis
FHJ99_RS00945	COG0363	glucosamine-6-phosphate deaminase activity
FHJ99_RS00950	COG0488	(ABC) transporter
FHJ99_RS00955	COG2814	Major facilitator Superfamily
FHJ99_RS00965	COG0222	ribosome binding
FHJ99_RS00970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FHJ99_RS00975	COG0081	regulation of translation
FHJ99_RS00980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FHJ99_RS00985	COG1760	l-serine dehydratase
FHJ99_RS00990	COG1760	l-serine dehydratase
FHJ99_RS00995	COG1304	FMN binding
FHJ99_RS01000	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FHJ99_RS01005	COG0250	Participates in transcription elongation, termination and antitermination
FHJ99_RS01010	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FHJ99_RS01015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHJ99_RS01030	COG1597	lipid kinase activity
FHJ99_RS01050	COG4585	Histidine kinase
FHJ99_RS01055	COG2197	response regulator
FHJ99_RS01065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FHJ99_RS01075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FHJ99_RS01080	COG2226	methyltransferase
FHJ99_RS01085	COG3142	Participates in the control of copper homeostasis
FHJ99_RS01090	COG2239	Acts as a magnesium transporter
FHJ99_RS01095	COG0564	pseudouridine synthase activity
FHJ99_RS01100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHJ99_RS01105	COG2357	RelA SpoT domain protein
FHJ99_RS01110	COG4116	CYTH
FHJ99_RS01130	COG4862	establishment of competence for transformation
FHJ99_RS01135	COG1393	Belongs to the ArsC family
FHJ99_RS01150	COG0419	ATPase involved in DNA repair
FHJ99_RS01155	COG0420	3'-5' exonuclease activity
FHJ99_RS01160	COG0204	Acyl-transferase
FHJ99_RS01165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FHJ99_RS01170	COG2827	Endonuclease containing a URI domain
FHJ99_RS01175	COG2755	lipolytic protein G-D-S-L family
FHJ99_RS01175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FHJ99_RS01180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJ99_RS01185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FHJ99_RS01190	COG0124	histidyl-tRNA synthetase
FHJ99_RS01200	COG0667	Aldo Keto reductase
FHJ99_RS01205	COG2124	cytochrome p450
FHJ99_RS01210	COG1490	D-aminoacyl-tRNA deacylase activity
FHJ99_RS01215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHJ99_RS01225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHJ99_RS01230	COG2264	protein methyltransferase activity
FHJ99_RS01240	COG2094	Belongs to the DNA glycosylase MPG family
FHJ99_RS01245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FHJ99_RS01260	COG0589	response to stress
FHJ99_RS01270	COG0488	(ABC) transporter
FHJ99_RS01275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHJ99_RS01280	COG0827	DNA restriction-modification system
FHJ99_RS01305	COG4537	Required for transformation and DNA binding
FHJ99_RS01310	COG1459	type II secretion system
FHJ99_RS01315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FHJ99_RS01320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FHJ99_RS01325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FHJ99_RS01335	COG4473	ABC transporter
FHJ99_RS01340	COG1131	(ABC) transporter
FHJ99_RS01345	COG0537	adenosine 5'-monophosphoramidase activity
FHJ99_RS01355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHJ99_RS01360	COG3481	metal-dependent phosphohydrolase, HD sub domain
FHJ99_RS01365	COG4717	serine-type aminopeptidase activity
FHJ99_RS01370	COG0420	3'-5' exonuclease activity
FHJ99_RS01380	COG0561	phosphatase activity
FHJ99_RS01415	COG2211	Major facilitator Superfamily
FHJ99_RS01425	COG3507	Belongs to the glycosyl hydrolase 43 family
FHJ99_RS01440	COG1073	alpha beta
FHJ99_RS01450	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FHJ99_RS01455	COG1653	transport
FHJ99_RS01465	COG4209	transmembrane transport
FHJ99_RS01470	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS01480	COG2207	Transcriptional regulator
FHJ99_RS01485	COG1609	Transcriptional regulator
FHJ99_RS01490	COG0246	Mannitol dehydrogenase
FHJ99_RS01495	COG2721	sulfolactate sulfo-lyase activity
FHJ99_RS01500	COG1904	glucuronate isomerase
FHJ99_RS01505	COG2755	lipolytic protein G-D-S-L family
FHJ99_RS01515	COG1132	(ABC) transporter
FHJ99_RS01520	COG3679	Belongs to the UPF0342 family
FHJ99_RS01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHJ99_RS01530	COG0564	pseudouridine synthase activity
FHJ99_RS01535	COG1940	carbohydrate kinase activity
FHJ99_RS01540	COG0383	alpha-mannosidase activity
FHJ99_RS01565	COG2207	Transcriptional regulator
FHJ99_RS01565	COG4753	response regulator
FHJ99_RS01570	COG2972	Histidine kinase
FHJ99_RS01585	COG1653	transport
FHJ99_RS01590	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS01595	COG1175	transmembrane transport
FHJ99_RS01605	COG1187	pseudouridine synthase activity
FHJ99_RS01610	COG2244	polysaccharide biosynthetic process
FHJ99_RS01620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FHJ99_RS01625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS01640	COG3711	transcriptional antiterminator
FHJ99_RS01640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS01685	COG4978	Transcriptional regulator
FHJ99_RS01685	COG0789	Transcriptional regulator
FHJ99_RS01695	COG1132	(ABC) transporter
FHJ99_RS01710	COG0495	leucyl-tRNA aminoacylation
FHJ99_RS01715	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHJ99_RS01715	COG1388	LysM domain
FHJ99_RS01720	COG0671	phosphoesterase, PA-phosphatase related
FHJ99_RS01725	COG1242	4 iron, 4 sulfur cluster binding
FHJ99_RS01730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FHJ99_RS01735	COG1132	(ABC) transporter
FHJ99_RS01740	COG1132	(ABC) transporter
FHJ99_RS01755	COG0477	Major facilitator Superfamily
FHJ99_RS01760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHJ99_RS01915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FHJ99_RS01920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHJ99_RS01925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FHJ99_RS01935	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FHJ99_RS01940	COG0037	tRNA processing
FHJ99_RS01945	COG1098	S1 RNA binding domain
FHJ99_RS01955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FHJ99_RS01960	COG2244	polysaccharide biosynthetic process
FHJ99_RS01965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHJ99_RS01970	COG0193	aminoacyl-tRNA hydrolase activity
FHJ99_RS01975	COG0039	L-malate dehydrogenase activity
FHJ99_RS01990	COG0217	transcriptional regulatory protein
FHJ99_RS02015	COG1792	Involved in formation and maintenance of cell shape
FHJ99_RS02025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FHJ99_RS02030	COG1162	GTPase activity
FHJ99_RS02035	COG0515	serine threonine protein kinase
FHJ99_RS02035	COG2815	serine threonine protein kinase
FHJ99_RS02040	COG0631	protein serine/threonine phosphatase activity
FHJ99_RS02045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHJ99_RS02045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHJ99_RS02050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHJ99_RS02055	COG0242	peptide deformylase activity
FHJ99_RS02060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHJ99_RS02065	COG1758	RNA polymerase activity
FHJ99_RS02070	COG0194	GDP metabolic process
FHJ99_RS02085	COG1561	YicC-like family, N-terminal region
FHJ99_RS02095	COG1752	Esterase of the alpha-beta hydrolase superfamily
FHJ99_RS02115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHJ99_RS02120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FHJ99_RS02125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHJ99_RS02130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHJ99_RS02135	COG1121	(ABC) transporter
FHJ99_RS02140	COG3443	Belongs to the bacterial solute-binding protein 9 family
FHJ99_RS02140	COG0803	Belongs to the bacterial solute-binding protein 9 family
FHJ99_RS02145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FHJ99_RS02150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHJ99_RS02150	COG0392	lysyltransferase activity
FHJ99_RS02155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHJ99_RS02160	COG1418	mRNA catabolic process
FHJ99_RS02165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FHJ99_RS02170	COG1058	Belongs to the CinA family
FHJ99_RS02170	COG1546	Belongs to the CinA family
FHJ99_RS02175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHJ99_RS02185	COG1426	Protein conserved in bacteria
FHJ99_RS02190	COG0612	Peptidase, M16
FHJ99_RS02195	COG0612	Peptidase, M16
FHJ99_RS02200	COG1970	mechanosensitive ion channel activity
FHJ99_RS02205	COG2153	protein acetylation
FHJ99_RS02210	COG4466	Protein conserved in bacteria
FHJ99_RS02220	COG3688	RNA-binding protein containing a PIN domain
FHJ99_RS02225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHJ99_RS02230	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FHJ99_RS02235	COG0215	cysteine-tRNA ligase activity
FHJ99_RS02240	COG1045	serine acetyltransferase
FHJ99_RS02245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHJ99_RS02250	COG4956	integral membrane protein (PIN domain superfamily)
FHJ99_RS02260	COG0756	dUTP diphosphatase activity
FHJ99_RS02270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FHJ99_RS02275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FHJ99_RS02295	COG2814	Major facilitator Superfamily
FHJ99_RS02325	COG0778	Nitroreductase
FHJ99_RS02335	COG1388	LysM domain
FHJ99_RS02335	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHJ99_RS02340	COG4221	oxidoreductase activity
FHJ99_RS02350	COG0583	DNA-binding transcription factor activity
FHJ99_RS02355	COG3711	transcriptional antiterminator
FHJ99_RS02360	COG1263	PTS System
FHJ99_RS02360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS02360	COG2190	(PTS) system
FHJ99_RS02365	COG0702	epimerase
FHJ99_RS02380	COG3708	Transcriptional regulator
FHJ99_RS02380	COG2207	Transcriptional regulator
FHJ99_RS02400	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FHJ99_RS02415	COG0604	alcohol dehydrogenase
FHJ99_RS02430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHJ99_RS02440	COG0842	Transport permease protein
FHJ99_RS02445	COG1131	(ABC) transporter
FHJ99_RS02455	COG2205	protein histidine kinase activity
FHJ99_RS02460	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FHJ99_RS02485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FHJ99_RS02490	COG0783	Belongs to the Dps family
FHJ99_RS02495	COG1070	Carbohydrate kinase
FHJ99_RS02500	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FHJ99_RS02505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHJ99_RS02510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS02520	COG1554	hydrolase, family 65, central catalytic
FHJ99_RS02525	COG0673	inositol 2-dehydrogenase activity
FHJ99_RS02530	COG1082	Xylose isomerase domain protein TIM barrel
FHJ99_RS02535	COG1063	alcohol dehydrogenase
FHJ99_RS02540	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS02545	COG1175	transmembrane transport
FHJ99_RS02550	COG1653	transport
FHJ99_RS02555	COG0366	Alpha amylase catalytic
FHJ99_RS02560	COG1609	Transcriptional regulator
FHJ99_RS02565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHJ99_RS02570	COG0085	RNA polymerase activity
FHJ99_RS02585	COG4120	Belongs to the binding-protein-dependent transport system permease family
FHJ99_RS02600	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FHJ99_RS02600	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FHJ99_RS02615	COG0142	geranyltranstransferase activity
FHJ99_RS02635	COG4939	FMN-binding domain protein
FHJ99_RS02655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHJ99_RS02660	COG0826	peptidase U32
FHJ99_RS02665	COG0826	peptidase U32
FHJ99_RS02670	COG0542	response to heat
FHJ99_RS02675	COG4463	regulation of RNA biosynthetic process
FHJ99_RS02755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FHJ99_RS02765	COG0517	IMP dehydrogenase activity
FHJ99_RS02765	COG0516	GMP reductase activity
FHJ99_RS02780	COG0012	GTP binding
FHJ99_RS02785	COG4481	Protein conserved in bacteria
FHJ99_RS02790	COG1475	DNA binding
FHJ99_RS02795	COG1192	Involved in chromosome partitioning
FHJ99_RS02800	COG0357	Ribosomal RNA small subunit methyltransferase G
FHJ99_RS02805	COG0445	tRNA wobble uridine modification
FHJ99_RS02810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FHJ99_RS02820	COG1847	R3H domain protein
FHJ99_RS02825	COG0706	membrane insertase activity
FHJ99_RS02830	COG0594	ribonuclease P activity
FHJ99_RS02835	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FHJ99_RS02845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FHJ99_RS02850	COG0592	DNA-directed DNA polymerase activity
FHJ99_RS02855	COG2501	S4 domain
FHJ99_RS02860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FHJ99_RS02865	COG0187	DNA topoisomerase II activity
FHJ99_RS02875	COG0360	Binds together with S18 to 16S ribosomal RNA
FHJ99_RS02880	COG0629	single-stranded DNA binding
FHJ99_RS02885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FHJ99_RS02895	COG0359	binds to the 23S rRNA
FHJ99_RS02900	COG0305	Participates in initiation and elongation during chromosome replication
FHJ99_RS02910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FHJ99_RS02925	COG0488	(ABC) transporter
FHJ99_RS02945	COG0028	Belongs to the TPP enzyme family
FHJ99_RS02970	COG4166	transmembrane transport
FHJ99_RS02975	COG0601	transmembrane transport
FHJ99_RS02980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJ99_RS02985	COG0444	Belongs to the ABC transporter superfamily
FHJ99_RS02990	COG4608	Belongs to the ABC transporter superfamily
FHJ99_RS03035	COG2814	Major facilitator Superfamily
FHJ99_RS03050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FHJ99_RS03050	COG0519	Catalyzes the synthesis of GMP from XMP
FHJ99_RS03055	COG1072	(Pantothenic acid kinase))
FHJ99_RS03060	COG2813	Specifically methylates the guanine in position
FHJ99_RS03070	COG1609	Transcriptional regulator
FHJ99_RS03075	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FHJ99_RS03080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FHJ99_RS03085	COG0295	cytidine deaminase activity
FHJ99_RS03090	COG1744	ABC transporter substrate-binding protein PnrA-like
FHJ99_RS03095	COG3845	ABC transporter
FHJ99_RS03100	COG4603	Belongs to the binding-protein-dependent transport system permease family
FHJ99_RS03105	COG1079	Belongs to the binding-protein-dependent transport system permease family
FHJ99_RS03110	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FHJ99_RS03120	COG0813	purine-nucleoside phosphorylase activity
FHJ99_RS03130	COG0588	phosphoglycerate mutase activity
FHJ99_RS03140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FHJ99_RS03145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FHJ99_RS03150	COG0049	tRNA binding
FHJ99_RS03155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHJ99_RS03160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FHJ99_RS03165	COG0051	transcription antitermination factor activity, RNA binding
FHJ99_RS03170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FHJ99_RS03175	COG0088	Forms part of the polypeptide exit tunnel
FHJ99_RS03180	COG0089	rRNA binding
FHJ99_RS03185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FHJ99_RS03195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FHJ99_RS03200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FHJ99_RS03205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FHJ99_RS03210	COG0255	Belongs to the universal ribosomal protein uL29 family
FHJ99_RS03215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FHJ99_RS03220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FHJ99_RS03225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FHJ99_RS03230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FHJ99_RS03235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHJ99_RS03240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FHJ99_RS03245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHJ99_RS03250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FHJ99_RS03255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FHJ99_RS03260	COG1841	ribosomal large subunit assembly
FHJ99_RS03265	COG0200	Binds to the 23S rRNA
FHJ99_RS03270	COG0201	protein transport
FHJ99_RS03275	COG0563	adenylate kinase activity
FHJ99_RS03280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FHJ99_RS03285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FHJ99_RS03290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FHJ99_RS03295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FHJ99_RS03300	COG0202	RNA polymerase activity
FHJ99_RS03305	COG0203	ribosomal protein L17
FHJ99_RS03310	COG1122	ATPase activity
FHJ99_RS03315	COG1122	ATPase activity
FHJ99_RS03325	COG0101	tRNA pseudouridine synthase activity
FHJ99_RS03335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FHJ99_RS03350	COG1461	Dihydroxyacetone kinase
FHJ99_RS03355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHJ99_RS03360	COG0416	fatty acid biosynthetic process
FHJ99_RS03365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHJ99_RS03375	COG4608	Belongs to the ABC transporter superfamily
FHJ99_RS03380	COG0601	transmembrane transport
FHJ99_RS03395	COG0571	ribonuclease III activity
FHJ99_RS03400	COG1196	nuclear chromosome segregation
FHJ99_RS03405	COG0561	phosphatase activity
FHJ99_RS03410	COG0552	protein localization to endoplasmic reticulum
FHJ99_RS03415	COG2918	glutathione biosynthetic process
FHJ99_RS03415	COG1181	Belongs to the D-alanine--D-alanine ligase family
FHJ99_RS03425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJ99_RS03430	COG4605	iron ion homeostasis
FHJ99_RS03435	COG4604	ABC transporter, ATP-binding protein
FHJ99_RS03440	COG4607	ABC-type enterochelin transport system periplasmic component
FHJ99_RS03465	COG4932	domain protein
FHJ99_RS03465	COG4886	Leucine-rich repeat (LRR) protein
FHJ99_RS03485	COG1380	Effector of murein hydrolase LrgA
FHJ99_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
FHJ99_RS03515	COG1268	BioY protein
FHJ99_RS03520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FHJ99_RS03535	COG0561	phosphatase activity
FHJ99_RS03545	COG1692	metallophosphoesterase
FHJ99_RS03555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FHJ99_RS03565	COG0424	maF-like protein
FHJ99_RS03570	COG1263	PTS System
FHJ99_RS03570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS03575	COG2188	Transcriptional regulator
FHJ99_RS03585	COG0632	four-way junction helicase activity
FHJ99_RS03590	COG2255	four-way junction helicase activity
FHJ99_RS03600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHJ99_RS03610	COG3328	transposase activity
FHJ99_RS03615	COG1114	Component of the transport system for branched-chain amino acids
FHJ99_RS03625	COG1113	amino acid transport
FHJ99_RS03630	COG1126	abc transporter atp-binding protein
FHJ99_RS03635	COG0765	amino acid transport
FHJ99_RS03650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHJ99_RS03655	COG0110	maltose O-acetyltransferase activity
FHJ99_RS03660	COG1827	regulation of RNA biosynthetic process
FHJ99_RS03670	COG0242	peptide deformylase activity
FHJ99_RS03675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FHJ99_RS03680	COG1185	polyribonucleotide nucleotidyltransferase activity
FHJ99_RS03695	COG3158	transport of potassium into the cell
FHJ99_RS03700	COG1253	flavin adenine dinucleotide binding
FHJ99_RS03705	COG0534	Mate efflux family protein
FHJ99_RS03715	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FHJ99_RS03720	COG1187	pseudouridine synthase activity
FHJ99_RS03725	COG1011	Hydrolase
FHJ99_RS03730	COG0572	uridine kinase
FHJ99_RS03755	COG1671	Belongs to the UPF0178 family
FHJ99_RS03765	COG1181	Belongs to the D-alanine--D-alanine ligase family
FHJ99_RS03770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHJ99_RS03780	COG0736	holo-[acyl-carrier-protein] synthase activity
FHJ99_RS03785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHJ99_RS03790	COG2337	Toxic component of a toxin-antitoxin (TA) module
FHJ99_RS03800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHJ99_RS03805	COG3321	synthase
FHJ99_RS03805	COG0604	alcohol dehydrogenase
FHJ99_RS03820	COG0531	amino acid
FHJ99_RS03850	COG1174	glycine betaine transport
FHJ99_RS03870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHJ99_RS03885	COG0343	queuine tRNA-ribosyltransferase activity
FHJ99_RS03890	COG1862	Preprotein translocase
FHJ99_RS03900	COG1454	alcohol dehydrogenase
FHJ99_RS03900	COG1012	belongs to the aldehyde dehydrogenase family
FHJ99_RS03905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FHJ99_RS03935	COG2207	Transcriptional regulator
FHJ99_RS03935	COG1917	Cupin 2, conserved barrel domain protein
FHJ99_RS03940	COG1070	Carbohydrate kinase
FHJ99_RS03945	COG4806	L-rhamnose isomerase
FHJ99_RS03950	COG0235	Class ii aldolase
FHJ99_RS03955	COG3254	rhamnose metabolic process
FHJ99_RS03960	COG1454	alcohol dehydrogenase
FHJ99_RS03965	COG1414	Transcriptional regulator
FHJ99_RS03970	COG0800	Aldolase
FHJ99_RS03980	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FHJ99_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
FHJ99_RS03990	COG1304	FMN binding
FHJ99_RS04005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHJ99_RS04010	COG1428	Deoxynucleoside kinase
FHJ99_RS04025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHJ99_RS04030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FHJ99_RS04035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FHJ99_RS04070	COG0824	Thioesterase
FHJ99_RS04075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FHJ99_RS04095	COG1363	Peptidase, m42
FHJ99_RS04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHJ99_RS04105	COG0589	response to stress
FHJ99_RS04110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS04115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHJ99_RS04120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FHJ99_RS04135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHJ99_RS04150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHJ99_RS04220	COG1401	restriction endodeoxyribonuclease activity
FHJ99_RS04230	COG3328	transposase activity
FHJ99_RS04250	COG2261	transglycosylase associated protein
FHJ99_RS04255	COG1764	response to oxidative stress
FHJ99_RS04315	COG1368	sulfuric ester hydrolase activity
FHJ99_RS04320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FHJ99_RS04330	COG0101	tRNA pseudouridine synthase activity
FHJ99_RS04355	COG0667	Aldo Keto reductase
FHJ99_RS04360	COG2186	Transcriptional regulator
FHJ99_RS04365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS04370	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS04380	COG1447	Phosphotransferase system cellobiose-specific component IIA
FHJ99_RS04385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS04400	COG1063	alcohol dehydrogenase
FHJ99_RS04410	COG4716	Myosin-crossreactive antigen
FHJ99_RS04450	COG1113	amino acid transport
FHJ99_RS04480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHJ99_RS04490	COG3052	prosthetic group binding
FHJ99_RS04560	COG1051	belongs to the nudix hydrolase family
FHJ99_RS04565	COG1846	Transcriptional regulator
FHJ99_RS04590	COG2252	PERMEase
FHJ99_RS04595	COG0366	Alpha amylase catalytic
FHJ99_RS04600	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS04610	COG1263	PTS System
FHJ99_RS04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS04610	COG2190	(PTS) system
FHJ99_RS04615	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS04630	COG1902	pentaerythritol trinitrate reductase activity
FHJ99_RS04640	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS04650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FHJ99_RS04655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FHJ99_RS04660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FHJ99_RS04670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHJ99_RS04690	COG1937	Protein conserved in bacteria
FHJ99_RS04695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHJ99_RS04700	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS04705	COG3973	AAA domain
FHJ99_RS04730	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FHJ99_RS04735	COG2376	Dihydroxyacetone kinase
FHJ99_RS04740	COG1461	Dihydroxyacetone kinase
FHJ99_RS04755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHJ99_RS04765	COG1131	(ABC) transporter
FHJ99_RS04770	COG1309	transcriptional regulator
FHJ99_RS04790	COG0531	amino acid
FHJ99_RS04795	COG1757	Na H antiporter
FHJ99_RS04800	COG1609	Transcriptional regulator
FHJ99_RS04810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS04820	COG1263	PTS System
FHJ99_RS04820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS04820	COG2190	(PTS) system
FHJ99_RS04850	COG3479	Phenolic acid decarboxylase
FHJ99_RS04855	COG1695	Transcriptional regulator
FHJ99_RS04865	COG2814	Major facilitator Superfamily
FHJ99_RS04895	COG0163	prenyltransferase activity
FHJ99_RS04900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FHJ99_RS04910	COG1136	(ABC) transporter
FHJ99_RS04910	COG0577	efflux transmembrane transporter activity
FHJ99_RS04930	COG1811	Na channel or pump
FHJ99_RS04965	COG1136	(ABC) transporter
FHJ99_RS04980	COG3942	CHAP domain
FHJ99_RS04980	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHJ99_RS04985	COG1263	PTS System
FHJ99_RS04985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS04985	COG2190	(PTS) system
FHJ99_RS04990	COG1869	D-ribose catabolic process
FHJ99_RS05000	COG1609	Transcriptional regulator
FHJ99_RS05020	COG0366	Alpha amylase catalytic
FHJ99_RS05030	COG0628	permease
FHJ99_RS05035	COG0803	Belongs to the bacterial solute-binding protein 9 family
FHJ99_RS05035	COG3443	Belongs to the bacterial solute-binding protein 9 family
FHJ99_RS05075	COG1428	Deoxynucleoside kinase
FHJ99_RS05090	COG0210	DNA helicase
FHJ99_RS05095	COG1393	Belongs to the ArsC family
FHJ99_RS05100	COG1393	Belongs to the ArsC family
FHJ99_RS05130	COG0386	Belongs to the glutathione peroxidase family
FHJ99_RS05135	COG1854	S-ribosylhomocysteine lyase activity
FHJ99_RS05140	COG0626	cystathionine gamma-synthase activity
FHJ99_RS05145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHJ99_RS05160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHJ99_RS05165	COG0019	diaminopimelate decarboxylase activity
FHJ99_RS05170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FHJ99_RS05180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FHJ99_RS05185	COG2171	N-acyltransferase activity
FHJ99_RS05190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHJ99_RS05195	COG0527	aspartate kinase activity
FHJ99_RS05200	COG1473	amidohydrolase
FHJ99_RS05205	COG0436	Aminotransferase
FHJ99_RS05210	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS05230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHJ99_RS05235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHJ99_RS05250	COG2207	Transcriptional regulator
FHJ99_RS05255	COG2249	NAD(P)H dehydrogenase (quinone) activity
FHJ99_RS05265	COG1113	amino acid transport
FHJ99_RS05270	COG1121	(ABC) transporter
FHJ99_RS05275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHJ99_RS05290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHJ99_RS05295	COG2823	Periplasmic or secreted lipoprotein
FHJ99_RS05295	COG1652	LysM domain
FHJ99_RS05305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHJ99_RS05310	COG0477	Major facilitator Superfamily
FHJ99_RS05320	COG1438	arginine binding
FHJ99_RS05335	COG1764	response to oxidative stress
FHJ99_RS05340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHJ99_RS05345	COG1335	isochorismatase
FHJ99_RS05360	COG2135	peptidase activity
FHJ99_RS05410	COG3546	catalase activity
FHJ99_RS05420	COG1175	transmembrane transport
FHJ99_RS05425	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS05460	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS05465	COG2205	protein histidine kinase activity
FHJ99_RS05475	COG0531	amino acid
FHJ99_RS05480	COG3853	Toxic anion resistance protein (TelA)
FHJ99_RS05500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHJ99_RS05505	COG1335	isochorismatase
FHJ99_RS05520	COG3590	peptidase
FHJ99_RS05530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHJ99_RS05535	COG1104	cysteine desulfurase activity
FHJ99_RS05555	COG0482	sulfurtransferase activity
FHJ99_RS05565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHJ99_RS05570	COG2814	Major facilitator Superfamily
FHJ99_RS05590	COG0463	Glycosyl transferase, family 2
FHJ99_RS05595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHJ99_RS05600	COG2855	membrane
FHJ99_RS05615	COG0583	DNA-binding transcription factor activity
FHJ99_RS05625	COG0772	Belongs to the SEDS family
FHJ99_RS05630	COG1393	Belongs to the ArsC family
FHJ99_RS05635	COG0509	glycine decarboxylation via glycine cleavage system
FHJ99_RS05640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHJ99_RS05645	COG2011	ABC-type metal ion transport system permease component
FHJ99_RS05650	COG1464	Belongs to the NlpA lipoprotein family
FHJ99_RS05660	COG0719	Fe-S assembly protein
FHJ99_RS05665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHJ99_RS05675	COG0719	Fe-S assembly protein
FHJ99_RS05765	COG1136	(ABC) transporter
FHJ99_RS05765	COG0577	efflux transmembrane transporter activity
FHJ99_RS05775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHJ99_RS05785	COG1597	lipid kinase activity
FHJ99_RS05835	COG3764	Sortase (surface protein transpeptidase)
FHJ99_RS05840	COG3711	transcriptional antiterminator
FHJ99_RS05845	COG1263	PTS System
FHJ99_RS05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS05845	COG2190	(PTS) system
FHJ99_RS05850	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS05855	COG2188	Transcriptional regulator
FHJ99_RS05880	COG1611	Belongs to the LOG family
FHJ99_RS05890	COG1428	Deoxynucleoside kinase
FHJ99_RS05905	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS05920	COG1368	sulfuric ester hydrolase activity
FHJ99_RS05930	COG0105	UTP biosynthetic process
FHJ99_RS05935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHJ99_RS05940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS05950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHJ99_RS05955	COG2011	ABC-type metal ion transport system permease component
FHJ99_RS05960	COG1464	Belongs to the NlpA lipoprotein family
FHJ99_RS05970	COG1757	Na H antiporter
FHJ99_RS05980	COG1113	amino acid transport
FHJ99_RS05990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHJ99_RS05995	COG1929	Belongs to the glycerate kinase type-1 family
FHJ99_RS06000	COG0488	(ABC) transporter
FHJ99_RS06015	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FHJ99_RS06020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS06020	COG1263	PTS System
FHJ99_RS06035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FHJ99_RS06040	COG1131	(ABC) transporter
FHJ99_RS06060	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FHJ99_RS06075	COG0346	lactoylglutathione lyase activity
FHJ99_RS06100	COG0561	phosphatase activity
FHJ99_RS06105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FHJ99_RS06110	COG0280	phosphate acetyltransferase
FHJ99_RS06115	COG0802	atpase or kinase
FHJ99_RS06120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHJ99_RS06135	COG0708	Exodeoxyribonuclease III
FHJ99_RS06145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FHJ99_RS06170	COG1053	succinate dehydrogenase
FHJ99_RS06180	COG3321	synthase
FHJ99_RS06180	COG1028	Short-chain dehydrogenase reductase Sdr
FHJ99_RS06180	COG0604	alcohol dehydrogenase
FHJ99_RS06185	COG0702	epimerase
FHJ99_RS06190	COG4684	Psort location CytoplasmicMembrane, score
FHJ99_RS06195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHJ99_RS06200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHJ99_RS06205	COG0604	alcohol dehydrogenase
FHJ99_RS06215	COG3842	ATPase activity
FHJ99_RS06220	COG1176	ABC-type spermidine putrescine transport system, permease component I
FHJ99_RS06225	COG1177	transmembrane transport
FHJ99_RS06230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FHJ99_RS06235	COG3829	transcription factor binding
FHJ99_RS06250	COG3715	PTS system
FHJ99_RS06255	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS06270	COG1940	carbohydrate kinase activity
FHJ99_RS06305	COG0582	viral genome integration into host DNA
FHJ99_RS06315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FHJ99_RS06325	COG0789	Transcriptional regulator
FHJ99_RS06370	COG0701	Predicted permease
FHJ99_RS06400	COG0504	CTP synthase activity
FHJ99_RS06415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHJ99_RS06420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FHJ99_RS06425	COG0254	rRNA binding
FHJ99_RS06450	COG1349	DNA-binding transcription factor activity
FHJ99_RS06460	COG2814	Major facilitator Superfamily
FHJ99_RS06470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHJ99_RS06490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHJ99_RS06495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FHJ99_RS06500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHJ99_RS06505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FHJ99_RS06510	COG3870	Protein conserved in bacteria
FHJ99_RS06515	COG0470	DNA polymerase III
FHJ99_RS06520	COG1774	PSP1 C-terminal conserved region
FHJ99_RS06525	COG4467	Involved in initiation control of chromosome replication
FHJ99_RS06540	COG0602	queuosine metabolic process
FHJ99_RS06545	COG1328	CTP reductase activity
FHJ99_RS06550	COG1136	(ABC) transporter
FHJ99_RS06555	COG0577	efflux transmembrane transporter activity
FHJ99_RS06570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FHJ99_RS06575	COG1696	Membrane protein involved in D-alanine export
FHJ99_RS06580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHJ99_RS06585	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHJ99_RS06590	COG1363	Peptidase, m42
FHJ99_RS06600	COG1234	tRNA 3'-trailer cleavage
FHJ99_RS06605	COG0095	Lipoate-protein ligase
FHJ99_RS06630	COG3759	membrane
FHJ99_RS06635	COG0659	secondary active sulfate transmembrane transporter activity
FHJ99_RS06645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FHJ99_RS06655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FHJ99_RS06660	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FHJ99_RS06660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FHJ99_RS06665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS06665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS06675	COG3715	PTS system
FHJ99_RS06680	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS06690	COG2261	transglycosylase associated protein
FHJ99_RS06695	COG0006	proline dipeptidase activity
FHJ99_RS06700	COG1302	Protein conserved in bacteria
FHJ99_RS06705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHJ99_RS06710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FHJ99_RS06715	COG1570	exodeoxyribonuclease VII activity
FHJ99_RS06720	COG1722	exodeoxyribonuclease VII activity
FHJ99_RS06730	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FHJ99_RS06735	COG1438	arginine binding
FHJ99_RS06740	COG0497	DNA recombination
FHJ99_RS06775	COG0768	penicillin binding
FHJ99_RS06810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHJ99_RS06815	COG1799	cell septum assembly
FHJ99_RS06825	COG2302	S4 RNA-binding domain
FHJ99_RS06830	COG3599	regulation of cell shape
FHJ99_RS06835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FHJ99_RS06840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FHJ99_RS06860	COG0673	inositol 2-dehydrogenase activity
FHJ99_RS06865	COG0513	Belongs to the DEAD box helicase family
FHJ99_RS06870	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FHJ99_RS06870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FHJ99_RS06875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS06880	COG1447	Phosphotransferase system cellobiose-specific component IIA
FHJ99_RS06885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS06925	COG2309	aminopeptidase activity
FHJ99_RS06935	COG0716	FMN binding
FHJ99_RS06940	COG0024	Methionine aminopeptidase
FHJ99_RS06945	COG1295	ribonuclease BN
FHJ99_RS06950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHJ99_RS06965	COG1215	transferase activity, transferring glycosyl groups
FHJ99_RS06970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHJ99_RS06980	COG1088	dTDP-glucose 4,6-dehydratase activity
FHJ99_RS06985	COG1091	dTDP-4-dehydrorhamnose reductase activity
FHJ99_RS07000	COG1682	transport, permease protein
FHJ99_RS07010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FHJ99_RS07015	COG1216	Glycosyl transferase, family 2
FHJ99_RS07015	COG0438	transferase activity, transferring glycosyl groups
FHJ99_RS07020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHJ99_RS07025	COG1216	Glycosyl transferase, family 2
FHJ99_RS07030	COG3475	LICD family
FHJ99_RS07045	COG1216	Glycosyl transferase, family 2
FHJ99_RS07055	COG3475	LICD family
FHJ99_RS07060	COG1215	transferase activity, transferring glycosyl groups
FHJ99_RS07080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHJ99_RS07085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FHJ99_RS07095	COG4585	Histidine kinase
FHJ99_RS07105	COG0569	domain protein
FHJ99_RS07130	COG2246	polysaccharide biosynthetic process
FHJ99_RS07135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHJ99_RS07145	COG1316	TRANSCRIPTIONal
FHJ99_RS07150	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FHJ99_RS07155	COG3397	chitin binding
FHJ99_RS07160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHJ99_RS07165	COG2137	regulation of response to DNA damage stimulus
FHJ99_RS07170	COG1194	a g-specific adenine glycosylase
FHJ99_RS07175	COG3557	Belongs to the UPF0374 family
FHJ99_RS07185	COG0628	permease
FHJ99_RS07190	COG1253	flavin adenine dinucleotide binding
FHJ99_RS07200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FHJ99_RS07220	COG0542	response to heat
FHJ99_RS07225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS07230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHJ99_RS07240	COG0438	transferase activity, transferring glycosyl groups
FHJ99_RS07245	COG2084	Dehydrogenase
FHJ99_RS07250	COG4703	Protein of unknown function (DUF1797)
FHJ99_RS07255	COG0322	excinuclease ABC activity
FHJ99_RS07260	COG1846	Transcriptional regulator
FHJ99_RS07265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHJ99_RS07275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHJ99_RS07285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FHJ99_RS07295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FHJ99_RS07300	COG0439	Biotin carboxylase
FHJ99_RS07305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FHJ99_RS07310	COG0825	malonyl-CoA metabolic process
FHJ99_RS07315	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FHJ99_RS07320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHJ99_RS07325	COG1534	Rna-binding protein
FHJ99_RS07330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHJ99_RS07335	COG1713	HD superfamily hydrolase involved in NAD metabolism
FHJ99_RS07340	COG0799	negative regulation of ribosome biogenesis
FHJ99_RS07345	COG2226	methyltransferase
FHJ99_RS07350	COG1323	Belongs to the UPF0348 family
FHJ99_RS07355	COG0217	transcriptional regulatory protein
FHJ99_RS07365	COG3973	AAA domain
FHJ99_RS07370	COG2217	Heavy metal translocating P-type atpase
FHJ99_RS07375	COG1942	4-Oxalocrotonate Tautomerase
FHJ99_RS07385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHJ99_RS07390	COG1737	Transcriptional regulator
FHJ99_RS07395	COG0768	penicillin binding
FHJ99_RS07400	COG0561	phosphatase activity
FHJ99_RS07405	COG2252	PERMEase
FHJ99_RS07410	COG2814	Major facilitator Superfamily
FHJ99_RS07420	COG0587	DNA-directed DNA polymerase activity
FHJ99_RS07425	COG0205	6-phosphofructokinase activity
FHJ99_RS07435	COG0583	DNA-binding transcription factor activity
FHJ99_RS07445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FHJ99_RS07450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FHJ99_RS07455	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS07460	COG5002	protein histidine kinase activity
FHJ99_RS07565	COG3711	transcriptional antiterminator
FHJ99_RS07575	COG2190	(PTS) system
FHJ99_RS07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS07575	COG1263	PTS System
FHJ99_RS07580	COG1486	melibiose metabolic process
FHJ99_RS07585	COG1263	PTS System
FHJ99_RS07585	COG2190	(PTS) system
FHJ99_RS07585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS07590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS07635	COG1309	transcriptional regulator
FHJ99_RS07640	COG2814	Major facilitator Superfamily
FHJ99_RS07660	COG1349	DNA-binding transcription factor activity
FHJ99_RS07685	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FHJ99_RS07690	COG3623	hexulose-6-phosphate isomerase
FHJ99_RS07700	COG0456	acetyltransferase
FHJ99_RS07725	COG3711	transcriptional antiterminator
FHJ99_RS07745	COG3775	system Galactitol-specific IIC component
FHJ99_RS07760	COG0400	carboxylic ester hydrolase activity
FHJ99_RS07765	COG0346	lactoylglutathione lyase activity
FHJ99_RS07775	COG2188	Transcriptional regulator
FHJ99_RS07780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS07785	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS07790	COG0589	response to stress
FHJ99_RS07805	COG1393	Belongs to the ArsC family
FHJ99_RS07815	COG0351	phosphomethylpyrimidine kinase
FHJ99_RS07820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHJ99_RS07825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHJ99_RS07835	COG3425	synthase
FHJ99_RS07840	COG0183	Belongs to the thiolase family
FHJ99_RS07855	COG0656	L-ascorbic acid biosynthetic process
FHJ99_RS07875	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHJ99_RS07875	COG0392	lysyltransferase activity
FHJ99_RS07880	COG0596	Alpha beta hydrolase
FHJ99_RS07885	COG0741	lytic transglycosylase activity
FHJ99_RS07895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHJ99_RS07900	COG0358	DNA primase activity
FHJ99_RS07905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHJ99_RS07915	COG2996	Protein conserved in bacteria
FHJ99_RS07920	COG0735	belongs to the Fur family
FHJ99_RS07925	COG4974	Belongs to the 'phage' integrase family
FHJ99_RS07935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FHJ99_RS07940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FHJ99_RS07945	COG1187	pseudouridine synthase activity
FHJ99_RS07950	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FHJ99_RS07955	COG1288	antiporter activity
FHJ99_RS07960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHJ99_RS07980	COG0514	ATP-dependent DNA helicase (RecQ)
FHJ99_RS07990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FHJ99_RS07995	COG0539	negative regulation of cytoplasmic translation
FHJ99_RS08000	COG1160	GTP binding
FHJ99_RS08005	COG0776	regulation of translation
FHJ99_RS08020	COG0457	Tetratricopeptide repeat
FHJ99_RS08025	COG5582	Belongs to the UPF0302 family
FHJ99_RS08030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJ99_RS08035	COG1694	Mazg nucleotide pyrophosphohydrolase
FHJ99_RS08040	COG0617	tRNA 3'-terminal CCA addition
FHJ99_RS08055	COG0025	NhaP-type Na H and K H
FHJ99_RS08060	COG0488	(ABC) transporter
FHJ99_RS08065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHJ99_RS08075	COG1272	protein, Hemolysin III
FHJ99_RS08080	COG1307	EDD domain protein, DegV family
FHJ99_RS08085	COG2755	lipolytic protein G-D-S-L family
FHJ99_RS08090	COG4698	Protein conserved in bacteria
FHJ99_RS08100	COG4479	Belongs to the UPF0346 family
FHJ99_RS08105	COG0681	Belongs to the peptidase S26 family
FHJ99_RS08120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHJ99_RS08125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHJ99_RS08130	COG0758	DNA mediated transformation
FHJ99_RS08135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHJ99_RS08140	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FHJ99_RS08145	COG4974	Belongs to the 'phage' integrase family
FHJ99_RS08150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FHJ99_RS08155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FHJ99_RS08170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FHJ99_RS08175	COG1832	CoA-binding protein
FHJ99_RS08180	COG0187	DNA topoisomerase II activity
FHJ99_RS08190	COG1882	Formate acetyltransferase
FHJ99_RS08195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHJ99_RS08200	COG1227	inorganic diphosphatase activity
FHJ99_RS08220	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FHJ99_RS08230	COG1073	alpha beta
FHJ99_RS08235	COG1609	Transcriptional regulator
FHJ99_RS08245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJ99_RS08265	COG1732	Glycine betaine
FHJ99_RS08280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FHJ99_RS08290	COG1116	anion transmembrane transporter activity
FHJ99_RS08295	COG0084	hydrolase, TatD family'
FHJ99_RS08300	COG1388	LysM domain
FHJ99_RS08300	COG3942	CHAP domain
FHJ99_RS08315	COG0346	lactoylglutathione lyase activity
FHJ99_RS08325	COG3328	transposase activity
FHJ99_RS08340	COG0436	Aminotransferase
FHJ99_RS08360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHJ99_RS08365	COG4565	transcriptional regulatory protein
FHJ99_RS08370	COG3290	protein histidine kinase activity
FHJ99_RS08375	COG3290	protein histidine kinase activity
FHJ99_RS08390	COG2268	Band 7 protein
FHJ99_RS08410	COG0673	inositol 2-dehydrogenase activity
FHJ99_RS08420	COG1876	peptidase activity
FHJ99_RS08425	COG1388	LysM domain
FHJ99_RS08425	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHJ99_RS08435	COG1653	transport
FHJ99_RS08440	COG1175	transmembrane transport
FHJ99_RS08445	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS08455	COG0673	inositol 2-dehydrogenase activity
FHJ99_RS08460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHJ99_RS08465	COG2233	PERMEase
FHJ99_RS08475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHJ99_RS08480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FHJ99_RS08485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHJ99_RS08495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FHJ99_RS08500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHJ99_RS08505	COG0047	phosphoribosylformylglycinamidine synthase activity
FHJ99_RS08510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHJ99_RS08520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FHJ99_RS08525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHJ99_RS08530	COG0138	bifunctional purine biosynthesis protein purh
FHJ99_RS08535	COG0151	Belongs to the GarS family
FHJ99_RS08540	COG4989	oxidoreductase activity
FHJ99_RS08550	COG2972	Histidine kinase
FHJ99_RS08560	COG4213	ABC transporter substrate-binding protein
FHJ99_RS08570	COG4214	carbohydrate transport
FHJ99_RS08575	COG0516	GMP reductase activity
FHJ99_RS08585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHJ99_RS08600	COG0022	dehydrogenase e1 component
FHJ99_RS08615	COG4476	Belongs to the UPF0223 family
FHJ99_RS08620	COG0483	inositol monophosphate 1-phosphatase activity
FHJ99_RS08625	COG1217	gtp-binding protein TYPA
FHJ99_RS08630	COG0514	ATP-dependent DNA helicase (RecQ)
FHJ99_RS08635	COG4838	Belongs to the UPF0358 family
FHJ99_RS08640	COG0772	Belongs to the SEDS family
FHJ99_RS08645	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FHJ99_RS08660	COG4471	UPF0298 protein
FHJ99_RS08665	COG0742	ribosomal rna small subunit methyltransferase
FHJ99_RS08670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHJ99_RS08675	COG3480	Lon protease (S16) C-terminal proteolytic domain
FHJ99_RS08680	COG1596	polysaccharide export
FHJ99_RS08680	COG1555	photosystem II stabilization
FHJ99_RS08695	COG2131	deaminase
FHJ99_RS08700	COG2333	competence protein COMEC
FHJ99_RS08700	COG0658	competence protein
FHJ99_RS08705	COG1466	dna polymerase III delta subunit
FHJ99_RS08710	COG0268	Binds directly to 16S ribosomal RNA
FHJ99_RS08720	COG2707	UPF0756 membrane protein
FHJ99_RS08725	COG2217	Heavy metal translocating P-type atpase
FHJ99_RS08730	COG1968	undecaprenyl-diphosphatase activity
FHJ99_RS08750	COG1666	GTP binding
FHJ99_RS08755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJ99_RS08760	COG2151	metal-sulfur cluster biosynthetic enzyme
FHJ99_RS08775	COG3942	CHAP domain
FHJ99_RS08775	COG1388	LysM domain
FHJ99_RS08830	COG4990	cell redox homeostasis
FHJ99_RS08850	COG3104	oligopeptide transport
FHJ99_RS08855	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FHJ99_RS08860	COG1074	ATP-dependent DNA helicase activity
FHJ99_RS08865	COG1733	regulation of RNA biosynthetic process
FHJ99_RS08870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FHJ99_RS08875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS08875	COG0072	phenylalanine-tRNA ligase activity
FHJ99_RS08885	COG1126	abc transporter atp-binding protein
FHJ99_RS08890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHJ99_RS08895	COG0765	amino acid transport
FHJ99_RS08900	COG0765	amino acid transport
FHJ99_RS08905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FHJ99_RS08910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FHJ99_RS08920	COG0517	IMP dehydrogenase activity
FHJ99_RS08925	COG0668	transmembrane transport
FHJ99_RS08935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHJ99_RS08940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FHJ99_RS08945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FHJ99_RS08970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHJ99_RS08980	COG1234	tRNA 3'-trailer cleavage
FHJ99_RS08985	COG0300	oxidoreductase activity
FHJ99_RS08990	COG5416	Lipopolysaccharide assembly protein A domain
FHJ99_RS08995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FHJ99_RS08995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FHJ99_RS09000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHJ99_RS09010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHJ99_RS09025	COG1388	LysM domain
FHJ99_RS09025	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHJ99_RS09030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHJ99_RS09035	COG0735	belongs to the Fur family
FHJ99_RS09040	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS09050	COG1846	Transcriptional regulator
FHJ99_RS09060	COG3935	DnaD domain protein
FHJ99_RS09065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHJ99_RS09075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHJ99_RS09080	COG3331	DNA recombination
FHJ99_RS09085	COG4474	Belongs to the UPF0398 family
FHJ99_RS09090	COG3599	regulation of cell shape
FHJ99_RS09100	COG0116	Belongs to the methyltransferase superfamily
FHJ99_RS09105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FHJ99_RS09110	COG1418	mRNA catabolic process
FHJ99_RS09125	COG0156	8-amino-7-oxononanoate synthase activity
FHJ99_RS09130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHJ99_RS09135	COG0531	amino acid
FHJ99_RS09150	COG0513	Belongs to the DEAD box helicase family
FHJ99_RS09155	COG2153	protein acetylation
FHJ99_RS09165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHJ99_RS09170	COG4684	Psort location CytoplasmicMembrane, score
FHJ99_RS09180	COG0328	RNA-DNA hybrid ribonuclease activity
FHJ99_RS09190	COG1278	Cold shock
FHJ99_RS09195	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FHJ99_RS09210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FHJ99_RS09215	COG0564	pseudouridine synthase activity
FHJ99_RS09225	COG2233	PERMEase
FHJ99_RS09230	COG0540	Belongs to the ATCase OTCase family
FHJ99_RS09235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FHJ99_RS09240	COG0505	Belongs to the CarA family
FHJ99_RS09245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FHJ99_RS09250	COG0543	2 iron, 2 sulfur cluster binding
FHJ99_RS09260	COG0284	orotidine-5'-phosphate decarboxylase activity
FHJ99_RS09290	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FHJ99_RS09305	COG4120	Belongs to the binding-protein-dependent transport system permease family
FHJ99_RS09315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FHJ99_RS09350	COG0039	L-malate dehydrogenase activity
FHJ99_RS09370	COG0582	viral genome integration into host DNA
FHJ99_RS09420	COG1131	(ABC) transporter
FHJ99_RS09425	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS09430	COG2205	protein histidine kinase activity
FHJ99_RS09450	COG0673	inositol 2-dehydrogenase activity
FHJ99_RS09485	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS09490	COG5002	protein histidine kinase activity
FHJ99_RS09495	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FHJ99_RS09505	COG0318	PFAM AMP-dependent synthetase and ligase
FHJ99_RS09510	COG0351	phosphomethylpyrimidine kinase
FHJ99_RS09520	COG4475	Protein of unknown function (DUF436)
FHJ99_RS09525	COG0366	Alpha amylase catalytic
FHJ99_RS09540	COG1307	EDD domain protein, DegV family
FHJ99_RS09545	COG2244	polysaccharide biosynthetic process
FHJ99_RS09600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHJ99_RS09605	COG0194	GDP metabolic process
FHJ99_RS09625	COG0765	amino acid transport
FHJ99_RS09630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHJ99_RS09640	COG0167	dihydroorotate dehydrogenase activity
FHJ99_RS09650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FHJ99_RS09660	COG3833	ABC-type maltose transport systems, permease component
FHJ99_RS09665	COG1175	transmembrane transport
FHJ99_RS09670	COG2182	Extracellular solute-binding protein
FHJ99_RS09675	COG0366	Alpha amylase catalytic
FHJ99_RS09680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHJ99_RS09690	COG1764	response to oxidative stress
FHJ99_RS09695	COG1846	Transcriptional regulator
FHJ99_RS09700	COG0628	permease
FHJ99_RS09715	COG1312	Catalyzes the dehydration of D-mannonate
FHJ99_RS09720	COG0246	Mannitol dehydrogenase
FHJ99_RS09730	COG0450	alkyl hydroperoxide reductase
FHJ99_RS09755	COG0768	penicillin binding
FHJ99_RS09775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FHJ99_RS09790	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHJ99_RS09805	COG0531	amino acid
FHJ99_RS09810	COG0004	ammonium transporteR
FHJ99_RS09820	COG2261	transglycosylase associated protein
FHJ99_RS09850	COG3655	Transcriptional regulator
FHJ99_RS09860	COG2261	transglycosylase associated protein
FHJ99_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
FHJ99_RS09895	COG1442	glycosyl transferase family 8
FHJ99_RS09900	COG1442	glycosyl transferase family 8
FHJ99_RS09905	COG0561	phosphatase activity
FHJ99_RS09930	COG1476	TRANSCRIPTIONal
FHJ99_RS09945	COG1278	Cold shock
FHJ99_RS09950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS09955	COG1312	Catalyzes the dehydration of D-mannonate
FHJ99_RS09975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS09980	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS09990	COG0371	Dehydrogenase
FHJ99_RS10000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FHJ99_RS10010	COG1737	Transcriptional regulator
FHJ99_RS10010	COG0837	glucose binding
FHJ99_RS10020	COG2272	Belongs to the type-B carboxylesterase lipase family
FHJ99_RS10025	COG1073	alpha beta
FHJ99_RS10060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHJ99_RS10080	COG3732	PTS system glucitol sorbitol-specific
FHJ99_RS10085	COG3730	PTS system glucitol sorbitol-specific
FHJ99_RS10095	COG3711	transcriptional antiterminator
FHJ99_RS10095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS10135	COG3328	transposase activity
FHJ99_RS10150	COG3279	Response regulator of the LytR AlgR family
FHJ99_RS10175	COG0656	L-ascorbic acid biosynthetic process
FHJ99_RS10190	COG0789	Transcriptional regulator
FHJ99_RS10195	COG1063	alcohol dehydrogenase
FHJ99_RS10210	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS10215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS10215	COG2190	(PTS) system
FHJ99_RS10215	COG1263	PTS System
FHJ99_RS10220	COG3711	transcriptional antiterminator
FHJ99_RS10245	COG0588	phosphoglycerate mutase activity
FHJ99_RS10260	COG0667	Aldo Keto reductase
FHJ99_RS10285	COG3344	reverse transcriptase
FHJ99_RS10290	COG0791	NLP P60 protein
FHJ99_RS10290	COG0741	lytic transglycosylase activity
FHJ99_RS10345	COG2946	Replication initiation factor
FHJ99_RS10350	COG1674	ftsk spoiiie
FHJ99_RS10390	COG3328	transposase activity
FHJ99_RS10395	COG3328	transposase activity
FHJ99_RS10405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FHJ99_RS10410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FHJ99_RS10415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FHJ99_RS10465	COG1278	Cold shock
FHJ99_RS10605	COG5484	DNA packaging
FHJ99_RS10650	COG3723	Recombinational DNA repair protein, rece pathway
FHJ99_RS10655	COG5377	YqaJ viral recombinase family
FHJ99_RS10680	COG1396	sequence-specific DNA binding
FHJ99_RS10705	COG4974	Belongs to the 'phage' integrase family
FHJ99_RS10710	COG0481	GTPase activity
FHJ99_RS10730	COG0542	response to heat
FHJ99_RS10745	COG1597	lipid kinase activity
FHJ99_RS10750	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHJ99_RS10755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHJ99_RS10760	COG2384	SAM-dependent methyltransferase
FHJ99_RS10770	COG1484	DNA-dependent DNA replication
FHJ99_RS10780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FHJ99_RS10790	COG0237	dephospho-CoA kinase activity
FHJ99_RS10795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FHJ99_RS10800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHJ99_RS10800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHJ99_RS10815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FHJ99_RS10820	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FHJ99_RS10825	COG3091	SprT-like family
FHJ99_RS10830	COG2183	response to ionizing radiation
FHJ99_RS10840	COG1054	Belongs to the UPF0176 family
FHJ99_RS10870	COG0546	phosphoglycolate phosphatase activity
FHJ99_RS10875	COG0588	phosphoglycerate mutase activity
FHJ99_RS10920	COG4753	response regulator
FHJ99_RS10920	COG2207	Transcriptional regulator
FHJ99_RS10930	COG2972	Histidine kinase
FHJ99_RS10935	COG0077	Prephenate dehydratase
FHJ99_RS10940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FHJ99_RS10945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FHJ99_RS10950	COG0287	Prephenate dehydrogenase
FHJ99_RS10955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FHJ99_RS10965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHJ99_RS10975	COG3250	beta-galactosidase activity
FHJ99_RS10990	COG1609	Transcriptional regulator
FHJ99_RS11000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FHJ99_RS11010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHJ99_RS11015	COG1597	lipid kinase activity
FHJ99_RS11020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHJ99_RS11025	COG0154	amidase activity
FHJ99_RS11030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHJ99_RS11035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FHJ99_RS11040	COG0210	DNA helicase
FHJ99_RS11050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHJ99_RS11050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS11050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHJ99_RS11055	COG1105	Belongs to the carbohydrate kinase PfkB family
FHJ99_RS11060	COG1349	DNA-binding transcription factor activity
FHJ99_RS11075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FHJ99_RS11080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FHJ99_RS11085	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHJ99_RS11095	COG1714	RDD family
FHJ99_RS11110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHJ99_RS11115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHJ99_RS11185	COG1481	regulation of sporulation
FHJ99_RS11190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FHJ99_RS11195	COG1660	Displays ATPase and GTPase activities
FHJ99_RS11210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FHJ99_RS11215	COG0556	nucleotide-excision repair
FHJ99_RS11220	COG0765	amino acid transport
FHJ99_RS11225	COG1126	abc transporter atp-binding protein
FHJ99_RS11235	COG3835	regulator
FHJ99_RS11240	COG0484	heat shock protein binding
FHJ99_RS11245	COG0443	Heat shock 70 kDa protein
FHJ99_RS11250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHJ99_RS11255	COG1420	regulation of RNA biosynthetic process
FHJ99_RS11260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHJ99_RS11270	COG0693	protein deglycase activity
FHJ99_RS11280	COG1619	proteins homologs of microcin C7 resistance protein MccF
FHJ99_RS11290	COG5646	InterPro IPR014922
FHJ99_RS11300	COG4975	Glucose uptake
FHJ99_RS11310	COG0196	riboflavin kinase activity
FHJ99_RS11315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHJ99_RS11320	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FHJ99_RS11325	COG1175	transmembrane transport
FHJ99_RS11330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FHJ99_RS11345	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FHJ99_RS11350	COG0195	Participates in both transcription termination and antitermination
FHJ99_RS11355	COG0779	Required for maturation of 30S ribosomal subunits
FHJ99_RS11360	COG2176	DNA-directed DNA polymerase activity
FHJ99_RS11365	COG0442	prolyl-tRNA aminoacylation
FHJ99_RS11370	COG0750	zinc metalloprotease
FHJ99_RS11375	COG4589	Belongs to the CDS family
FHJ99_RS11380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FHJ99_RS11385	COG0233	cytoplasmic translational termination
FHJ99_RS11390	COG0528	UMP kinase activity
FHJ99_RS11395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FHJ99_RS11400	COG0052	Belongs to the universal ribosomal protein uS2 family
FHJ99_RS11405	COG1438	arginine binding
FHJ99_RS11415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS11425	COG0018	arginyl-trna synthetase
FHJ99_RS11440	COG2235	arginine
FHJ99_RS11445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHJ99_RS11450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FHJ99_RS11455	COG0456	acetyltransferase
FHJ99_RS11465	COG1214	PFAM Peptidase M22, glycoprotease
FHJ99_RS11470	COG1609	Transcriptional regulator
FHJ99_RS11475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FHJ99_RS11480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHJ99_RS11495	COG3189	MarR family transcriptional regulator
FHJ99_RS11500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHJ99_RS11505	COG1940	carbohydrate kinase activity
FHJ99_RS11520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHJ99_RS11525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJ99_RS11530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHJ99_RS11535	COG1120	ATPase activity
FHJ99_RS11550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHJ99_RS11555	COG4876	unkown
FHJ99_RS11560	COG0367	asparagine synthase
FHJ99_RS11565	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FHJ99_RS11845	COG4974	Belongs to the 'phage' integrase family
FHJ99_RS11855	COG1309	transcriptional regulator
FHJ99_RS11875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FHJ99_RS11885	COG0584	glycerophosphoryl diester phosphodiesterase
FHJ99_RS11900	COG0166	Belongs to the GPI family
FHJ99_RS11905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHJ99_RS11910	COG2081	HI0933 family
FHJ99_RS11915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FHJ99_RS11920	COG0710	3-dehydroquinate dehydratase activity
FHJ99_RS11925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FHJ99_RS11930	COG1368	sulfuric ester hydrolase activity
FHJ99_RS11950	COG5002	protein histidine kinase activity
FHJ99_RS11950	COG3850	Histidine kinase
FHJ99_RS11955	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS11995	COG1956	GAF domain-containing protein
FHJ99_RS12000	COG3527	Alpha-acetolactate decarboxylase
FHJ99_RS12005	COG0028	Belongs to the TPP enzyme family
FHJ99_RS12015	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS12025	COG0583	DNA-binding transcription factor activity
FHJ99_RS12030	COG0789	Transcriptional regulator
FHJ99_RS12035	COG2814	Major facilitator Superfamily
FHJ99_RS12105	COG0335	large ribosomal subunit rRNA binding
FHJ99_RS12110	COG0336	Belongs to the RNA methyltransferase TrmD family
FHJ99_RS12115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FHJ99_RS12125	COG1837	Belongs to the UPF0109 family
FHJ99_RS12130	COG0228	four-way junction DNA binding
FHJ99_RS12135	COG0431	NADPH-dependent FMN reductase
FHJ99_RS12140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FHJ99_RS12145	COG0519	Catalyzes the synthesis of GMP from XMP
FHJ99_RS12150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHJ99_RS12155	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FHJ99_RS12165	COG0745	RESPONSE REGULATOR receiver
FHJ99_RS12170	COG5002	protein histidine kinase activity
FHJ99_RS12180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHJ99_RS12185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FHJ99_RS12205	COG3328	transposase activity
FHJ99_RS12235	COG0714	Associated with various cellular activities
FHJ99_RS12250	COG2217	Heavy metal translocating P-type atpase
FHJ99_RS12255	COG2217	Heavy metal translocating P-type atpase
FHJ99_RS12260	COG2608	mercury ion transmembrane transporter activity
FHJ99_RS12265	COG3682	Transcriptional regulator
FHJ99_RS12280	COG0531	amino acid
FHJ99_RS12285	COG2217	Heavy metal translocating P-type atpase
FHJ99_RS12310	COG0017	Asparaginyl-tRNA synthetase
FHJ99_RS12315	COG0436	Aminotransferase
FHJ99_RS12325	COG1199	ATP-dependent helicase activity
FHJ99_RS12325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FHJ99_RS12330	COG1278	Cold shock
FHJ99_RS12345	COG1686	Belongs to the peptidase S11 family
FHJ99_RS12355	COG0038	chloride channel
FHJ99_RS12375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHJ99_RS12380	COG1254	Belongs to the acylphosphatase family
FHJ99_RS12395	COG0706	membrane insertase activity
FHJ99_RS12400	COG3684	Belongs to the aldolase LacD family
FHJ99_RS12405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHJ99_RS12405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS12405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS12410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHJ99_RS12410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHJ99_RS12410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHJ99_RS12415	COG1105	Belongs to the carbohydrate kinase PfkB family
FHJ99_RS12465	COG1086	Polysaccharide biosynthesis protein
FHJ99_RS12475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHJ99_RS12485	COG4464	protein tyrosine phosphatase activity
FHJ99_RS12490	COG0489	protein tyrosine kinase activity
FHJ99_RS12495	COG3944	biosynthesis protein
FHJ99_RS12500	COG1316	TRANSCRIPTIONal
FHJ99_RS12510	COG0751	glycine-tRNA ligase activity
FHJ99_RS12515	COG0752	glycyl-tRNA synthetase alpha subunit
FHJ99_RS12520	COG1381	Involved in DNA repair and RecF pathway recombination
FHJ99_RS12525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHJ99_RS12530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FHJ99_RS12535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FHJ99_RS12545	COG1702	phosphate starvation-inducible protein PhoH
FHJ99_RS12550	COG1114	Component of the transport system for branched-chain amino acids
FHJ99_RS12555	COG1610	YqeY-like protein
FHJ99_RS12560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FHJ99_RS12565	COG0735	belongs to the Fur family
FHJ99_RS12570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FHJ99_RS12575	COG0640	Transcriptional regulator
FHJ99_RS12580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHJ99_RS12585	COG0492	ferredoxin-NADP+ reductase activity
FHJ99_RS12590	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS12595	COG1486	melibiose metabolic process
FHJ99_RS12610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS12610	COG1263	PTS System
FHJ99_RS12610	COG2190	(PTS) system
FHJ99_RS12615	COG3711	transcriptional antiterminator
FHJ99_RS12620	COG1132	(ABC) transporter
FHJ99_RS12625	COG1132	(ABC) transporter
FHJ99_RS12630	COG3763	UPF0154 protein
FHJ99_RS12635	COG1914	H( )-stimulated, divalent metal cation uptake system
FHJ99_RS12645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FHJ99_RS12655	COG1609	Transcriptional regulator
FHJ99_RS12665	COG4980	gas vesicle protein
FHJ99_RS12675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FHJ99_RS12680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FHJ99_RS12685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FHJ99_RS12690	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FHJ99_RS12695	COG1950	PFAM Membrane protein of
FHJ99_RS12720	COG0704	Plays a role in the regulation of phosphate uptake
FHJ99_RS12725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FHJ99_RS12730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FHJ99_RS12735	COG0581	inorganic phosphate transmembrane transporter activity
FHJ99_RS12740	COG0573	inorganic phosphate transmembrane transporter activity
FHJ99_RS12745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FHJ99_RS12760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHJ99_RS12765	COG2177	Part of the ABC transporter FtsEX involved in
FHJ99_RS12770	COG2884	Cell division ATP-binding protein ftsE
FHJ99_RS12780	COG0653	protein targeting
FHJ99_RS12795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FHJ99_RS12800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS12810	COG1739	Uncharacterized protein family UPF0029
FHJ99_RS12815	COG2188	Transcriptional regulator
FHJ99_RS12835	COG1940	carbohydrate kinase activity
FHJ99_RS12855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHJ99_RS12865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FHJ99_RS12870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FHJ99_RS12875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FHJ99_RS12880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FHJ99_RS12885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHJ99_RS12890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FHJ99_RS12895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHJ99_RS12900	COG0356	it plays a direct role in the translocation of protons across the membrane
FHJ99_RS12905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FHJ99_RS12910	COG0557	exoribonuclease II activity
FHJ99_RS12920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FHJ99_RS12925	COG2388	GCN5-related N-acetyl-transferase
FHJ99_RS12945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHJ99_RS12955	COG0149	triose-phosphate isomerase activity
FHJ99_RS12960	COG0126	phosphoglycerate kinase activity
FHJ99_RS12970	COG2390	Transcriptional regulator
FHJ99_RS12975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FHJ99_RS12995	COG1595	DNA-templated transcription, initiation
FHJ99_RS13015	COG0095	Lipoate-protein ligase
FHJ99_RS13020	COG1078	dGTPase activity
FHJ99_RS13025	COG0561	phosphatase activity
FHJ99_RS13030	COG0494	nUDIX hydrolase
FHJ99_RS13035	COG0346	lactoylglutathione lyase activity
FHJ99_RS13045	COG2423	ornithine cyclodeaminase activity
FHJ99_RS13050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHJ99_RS13055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHJ99_RS13060	COG1394	ATPase activity, coupled to movement of substances
FHJ99_RS13065	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FHJ99_RS13070	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FHJ99_RS13075	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FHJ99_RS13080	COG1527	subunit (C
FHJ99_RS13085	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FHJ99_RS13090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHJ99_RS13095	COG1269	ATP hydrolysis coupled proton transport
FHJ99_RS13105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FHJ99_RS13110	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FHJ99_RS13120	COG4152	abc transporter atp-binding protein
FHJ99_RS13125	COG0322	excinuclease ABC activity
FHJ99_RS13130	COG3118	belongs to the thioredoxin family
FHJ99_RS13135	COG1193	negative regulation of DNA recombination
FHJ99_RS13150	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHJ99_RS13165	COG1136	(ABC) transporter
FHJ99_RS13175	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS13210	COG1304	FMN binding
FHJ99_RS13220	COG0281	malic enzyme
FHJ99_RS13310	COG0582	viral genome integration into host DNA
FHJ99_RS13315	COG3906	Belongs to the UPF0473 family
FHJ99_RS13320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FHJ99_RS13325	COG4472	Bacterial protein of unknown function (DUF965)
FHJ99_RS13355	COG4555	ABC transporter
FHJ99_RS13365	COG3689	TIGRFAM TIGR03943 family protein
FHJ99_RS13370	COG0701	Predicted permease
FHJ99_RS13375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHJ99_RS13380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHJ99_RS13385	COG0488	(ABC) transporter
FHJ99_RS13390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FHJ99_RS13405	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS13425	COG2207	Transcriptional regulator
FHJ99_RS13425	COG0662	Cupin 2, conserved barrel domain protein
FHJ99_RS13430	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHJ99_RS13440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHJ99_RS13445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHJ99_RS13450	COG0584	glycerophosphoryl diester phosphodiesterase
FHJ99_RS13460	COG0740	serine-type endopeptidase activity
FHJ99_RS13465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FHJ99_RS13475	COG1132	(ABC) transporter
FHJ99_RS13485	COG5503	Protein of unknown function (DUF1447)
FHJ99_RS13500	COG1278	Cold shock
FHJ99_RS13505	COG2003	Belongs to the UPF0758 family
FHJ99_RS13510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHJ99_RS13515	COG0285	dihydrofolate synthase activity
FHJ99_RS13520	COG0525	valine-tRNA ligase activity
FHJ99_RS13525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHJ99_RS13530	COG0301	tRNA thio-modification
FHJ99_RS13535	COG1104	cysteine desulfurase activity
FHJ99_RS13540	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FHJ99_RS13550	COG0561	phosphatase activity
FHJ99_RS13555	COG1801	Protein of unknown function DUF72
FHJ99_RS13575	COG3579	cysteine-type endopeptidase activity
FHJ99_RS13640	COG1098	S1 RNA binding domain
FHJ99_RS13645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FHJ99_RS13660	COG0492	ferredoxin-NADP+ reductase activity
FHJ99_RS13665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FHJ99_RS13680	COG4470	Protein conserved in bacteria
FHJ99_RS13685	COG0737	Belongs to the 5'-nucleotidase family
FHJ99_RS13700	COG0590	tRNA wobble adenosine to inosine editing
FHJ99_RS13705	COG2508	Transcriptional regulator
FHJ99_RS13715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHJ99_RS13715	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FHJ99_RS13730	COG2738	Putative neutral zinc metallopeptidase
FHJ99_RS13735	COG2824	Alkylphosphonate utilization operon protein PhnA
FHJ99_RS13740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHJ99_RS13745	COG4109	DRTGG domain
FHJ99_RS13750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FHJ99_RS13770	COG0577	efflux transmembrane transporter activity
FHJ99_RS13775	COG1136	(ABC) transporter
FHJ99_RS13785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FHJ99_RS13790	COG1288	antiporter activity
FHJ99_RS13795	COG4821	SIS domain
FHJ99_RS13815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FHJ99_RS13825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FHJ99_RS13830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHJ99_RS13835	COG3716	PTS system mannose fructose sorbose family IID component
FHJ99_RS13840	COG3715	PTS system
FHJ99_RS13865	COG1132	(ABC) transporter
FHJ99_RS13870	COG1132	(ABC) transporter
FHJ99_RS13880	COG1803	Methylglyoxal synthase
FHJ99_RS13885	COG3842	ATPase activity
FHJ99_RS13895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FHJ99_RS13900	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FHJ99_RS13905	COG0084	hydrolase, TatD family'
FHJ99_RS13910	COG0531	amino acid
FHJ99_RS13920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS13920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHJ99_RS13940	COG0675	Transposase, IS605 OrfB family
FHJ99_RS13945	COG4608	Belongs to the ABC transporter superfamily
FHJ99_RS13950	COG0444	Belongs to the ABC transporter superfamily
FHJ99_RS13955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHJ99_RS13960	COG0601	transmembrane transport
FHJ99_RS13970	COG4166	transmembrane transport
FHJ99_RS13995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FHJ99_RS14000	COG1280	lysine exporter protein (LysE YggA)
FHJ99_RS14000	COG1674	ftsk spoiiie
FHJ99_RS14005	COG2723	6-phospho-beta-galactosidase activity
FHJ99_RS14015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHJ99_RS14020	COG1126	abc transporter atp-binding protein
FHJ99_RS14025	COG0765	amino acid transport
FHJ99_RS14275	COG0629	single-stranded DNA binding
FHJ99_RS14475	COG0582	viral genome integration into host DNA
FHJ99_RS14480	COG4974	Belongs to the 'phage' integrase family
FHJ99_RS14525	COG1263	PTS System
FHJ99_RS14525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS14525	COG2190	(PTS) system
FHJ99_RS14530	COG1263	PTS System
FHJ99_RS14530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHJ99_RS14530	COG2190	(PTS) system
FHJ99_RS14535	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FHJ99_RS14550	COG3328	transposase activity
FHJ99_RS14570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHJ99_RS14580	COG3684	Belongs to the aldolase LacD family
FHJ99_RS14585	COG2222	sugar isomerase
FHJ99_RS14590	COG2188	Transcriptional regulator
FHJ99_RS14605	COG3842	ATPase activity
FHJ99_RS14615	COG0395	ABC-type sugar transport system, permease component
FHJ99_RS14630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family