locus-tag	class	description
CEQ01_RS00025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEQ01_RS00095	COG0582	viral genome integration into host DNA
CEQ01_RS00120	COG4974	Belongs to the 'phage' integrase family
CEQ01_RS00150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ01_RS00215	COG0791	NLP P60 protein
CEQ01_RS00215	COG0741	lytic transglycosylase activity
CEQ01_RS00245	COG2946	Replication initiation factor
CEQ01_RS00255	COG1674	ftsk spoiiie
CEQ01_RS00280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS00285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ01_RS00285	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEQ01_RS00290	COG2222	sugar isomerase
CEQ01_RS00295	COG3716	PTS system mannose fructose sorbose family IID component
CEQ01_RS00300	COG3715	PTS system
CEQ01_RS00390	COG0629	single-stranded DNA binding
CEQ01_RS00580	COG3328	transposase activity
CEQ01_RS00610	COG2222	sugar isomerase
CEQ01_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ01_RS00620	COG2188	Transcriptional regulator
CEQ01_RS00640	COG1288	antiporter activity
CEQ01_RS00680	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEQ01_RS00680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ01_RS00685	COG1263	PTS System
CEQ01_RS00685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS00685	COG2190	(PTS) system
CEQ01_RS00690	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS00695	COG3711	transcriptional antiterminator
CEQ01_RS00720	COG0783	Belongs to the Dps family
CEQ01_RS00725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ01_RS00735	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEQ01_RS00740	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS00760	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS00785	COG1609	Transcriptional regulator
CEQ01_RS00795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS00805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS00805	COG1263	PTS System
CEQ01_RS00805	COG2190	(PTS) system
CEQ01_RS00835	COG4821	SIS domain
CEQ01_RS00845	COG1288	antiporter activity
CEQ01_RS00850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ01_RS00860	COG1136	(ABC) transporter
CEQ01_RS00865	COG0577	efflux transmembrane transporter activity
CEQ01_RS00885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEQ01_RS00890	COG4109	DRTGG domain
CEQ01_RS00895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEQ01_RS00900	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ01_RS00905	COG2738	Putative neutral zinc metallopeptidase
CEQ01_RS00920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ01_RS00920	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CEQ01_RS00930	COG2508	Transcriptional regulator
CEQ01_RS00935	COG0590	tRNA wobble adenosine to inosine editing
CEQ01_RS00950	COG0737	Belongs to the 5'-nucleotidase family
CEQ01_RS00955	COG4470	Protein conserved in bacteria
CEQ01_RS00970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEQ01_RS00975	COG0492	ferredoxin-NADP+ reductase activity
CEQ01_RS00985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEQ01_RS00990	COG1098	S1 RNA binding domain
CEQ01_RS01040	COG0531	amino acid
CEQ01_RS01045	COG2957	Belongs to the agmatine deiminase family
CEQ01_RS01050	COG0549	Belongs to the carbamate kinase family
CEQ01_RS01100	COG3328	transposase activity
CEQ01_RS01120	COG3711	transcriptional antiterminator
CEQ01_RS01125	COG2190	(PTS) system
CEQ01_RS01125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS01125	COG1263	PTS System
CEQ01_RS01130	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS01160	COG3579	cysteine-type endopeptidase activity
CEQ01_RS01180	COG1801	Protein of unknown function DUF72
CEQ01_RS01185	COG0561	phosphatase activity
CEQ01_RS01195	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CEQ01_RS01200	COG1104	cysteine desulfurase activity
CEQ01_RS01205	COG0301	tRNA thio-modification
CEQ01_RS01210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEQ01_RS01215	COG0525	valine-tRNA ligase activity
CEQ01_RS01220	COG0285	dihydrofolate synthase activity
CEQ01_RS01225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS01230	COG2003	Belongs to the UPF0758 family
CEQ01_RS01235	COG1278	Cold shock
CEQ01_RS01250	COG5503	Protein of unknown function (DUF1447)
CEQ01_RS01260	COG1132	(ABC) transporter
CEQ01_RS01270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEQ01_RS01275	COG0740	serine-type endopeptidase activity
CEQ01_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ01_RS01290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEQ01_RS01295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEQ01_RS01300	COG0789	Transcriptional regulator
CEQ01_RS01320	COG0504	CTP synthase activity
CEQ01_RS01335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ01_RS01340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEQ01_RS01345	COG0254	rRNA binding
CEQ01_RS01360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS01360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS01370	COG1349	DNA-binding transcription factor activity
CEQ01_RS01380	COG2814	Major facilitator Superfamily
CEQ01_RS01390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ01_RS01415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CEQ01_RS01420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEQ01_RS01425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEQ01_RS01430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEQ01_RS01435	COG3870	Protein conserved in bacteria
CEQ01_RS01440	COG0470	DNA polymerase III
CEQ01_RS01445	COG1774	PSP1 C-terminal conserved region
CEQ01_RS01450	COG4467	Involved in initiation control of chromosome replication
CEQ01_RS01465	COG0602	queuosine metabolic process
CEQ01_RS01470	COG1328	CTP reductase activity
CEQ01_RS01475	COG1136	(ABC) transporter
CEQ01_RS01480	COG0577	efflux transmembrane transporter activity
CEQ01_RS01495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEQ01_RS01500	COG1696	Membrane protein involved in D-alanine export
CEQ01_RS01505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ01_RS01510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CEQ01_RS01515	COG1363	Peptidase, m42
CEQ01_RS01525	COG1234	tRNA 3'-trailer cleavage
CEQ01_RS01530	COG0095	Lipoate-protein ligase
CEQ01_RS01555	COG3759	membrane
CEQ01_RS01560	COG0659	secondary active sulfate transmembrane transporter activity
CEQ01_RS01570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEQ01_RS01580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ01_RS01585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ01_RS01585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEQ01_RS01590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS01590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS01600	COG3715	PTS system
CEQ01_RS01605	COG3716	PTS system mannose fructose sorbose family IID component
CEQ01_RS01615	COG2261	transglycosylase associated protein
CEQ01_RS01620	COG0006	proline dipeptidase activity
CEQ01_RS01625	COG1302	Protein conserved in bacteria
CEQ01_RS01630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ01_RS01635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEQ01_RS01640	COG1570	exodeoxyribonuclease VII activity
CEQ01_RS01645	COG1722	exodeoxyribonuclease VII activity
CEQ01_RS01655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CEQ01_RS01660	COG1438	arginine binding
CEQ01_RS01665	COG0497	DNA recombination
CEQ01_RS01700	COG0768	penicillin binding
CEQ01_RS01735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ01_RS01740	COG1799	cell septum assembly
CEQ01_RS01750	COG2302	S4 RNA-binding domain
CEQ01_RS01755	COG3599	regulation of cell shape
CEQ01_RS01760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEQ01_RS01765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ01_RS01785	COG0673	inositol 2-dehydrogenase activity
CEQ01_RS01790	COG0513	Belongs to the DEAD box helicase family
CEQ01_RS01795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ01_RS01795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CEQ01_RS01800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS01805	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEQ01_RS01810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS01850	COG2309	aminopeptidase activity
CEQ01_RS01860	COG0716	FMN binding
CEQ01_RS01865	COG0024	Methionine aminopeptidase
CEQ01_RS01870	COG1295	ribonuclease BN
CEQ01_RS01875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ01_RS01890	COG1215	transferase activity, transferring glycosyl groups
CEQ01_RS01895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEQ01_RS01905	COG1088	dTDP-glucose 4,6-dehydratase activity
CEQ01_RS01910	COG1091	dTDP-4-dehydrorhamnose reductase activity
CEQ01_RS01925	COG1682	transport, permease protein
CEQ01_RS01935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ01_RS01940	COG0438	transferase activity, transferring glycosyl groups
CEQ01_RS01940	COG1216	Glycosyl transferase, family 2
CEQ01_RS01945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEQ01_RS01950	COG1216	Glycosyl transferase, family 2
CEQ01_RS01955	COG3475	LICD family
CEQ01_RS01970	COG1216	Glycosyl transferase, family 2
CEQ01_RS01980	COG3475	LICD family
CEQ01_RS01985	COG1215	transferase activity, transferring glycosyl groups
CEQ01_RS02005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEQ01_RS02010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ01_RS02020	COG4585	Histidine kinase
CEQ01_RS02030	COG0569	domain protein
CEQ01_RS02055	COG2246	polysaccharide biosynthetic process
CEQ01_RS02060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEQ01_RS02075	COG1316	TRANSCRIPTIONal
CEQ01_RS02080	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CEQ01_RS02085	COG3397	chitin binding
CEQ01_RS02090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ01_RS02095	COG2137	regulation of response to DNA damage stimulus
CEQ01_RS02100	COG1194	a g-specific adenine glycosylase
CEQ01_RS02105	COG3557	Belongs to the UPF0374 family
CEQ01_RS02115	COG0628	permease
CEQ01_RS02120	COG1253	flavin adenine dinucleotide binding
CEQ01_RS02130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEQ01_RS02150	COG0542	response to heat
CEQ01_RS02155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS02160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ01_RS02170	COG0438	transferase activity, transferring glycosyl groups
CEQ01_RS02175	COG2084	Dehydrogenase
CEQ01_RS02180	COG4703	Protein of unknown function (DUF1797)
CEQ01_RS02185	COG0322	excinuclease ABC activity
CEQ01_RS02190	COG1846	Transcriptional regulator
CEQ01_RS02195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ01_RS02205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEQ01_RS02215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ01_RS02225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ01_RS02230	COG0439	Biotin carboxylase
CEQ01_RS02235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ01_RS02240	COG0825	malonyl-CoA metabolic process
CEQ01_RS02245	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CEQ01_RS02250	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEQ01_RS02255	COG1534	Rna-binding protein
CEQ01_RS02260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ01_RS02265	COG1713	HD superfamily hydrolase involved in NAD metabolism
CEQ01_RS02270	COG0799	negative regulation of ribosome biogenesis
CEQ01_RS02275	COG2226	methyltransferase
CEQ01_RS02280	COG1323	Belongs to the UPF0348 family
CEQ01_RS02285	COG0217	transcriptional regulatory protein
CEQ01_RS02295	COG3973	AAA domain
CEQ01_RS02300	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS02305	COG1942	4-Oxalocrotonate Tautomerase
CEQ01_RS02315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEQ01_RS02320	COG1737	Transcriptional regulator
CEQ01_RS02325	COG0768	penicillin binding
CEQ01_RS02330	COG0561	phosphatase activity
CEQ01_RS02335	COG2252	PERMEase
CEQ01_RS02340	COG2814	Major facilitator Superfamily
CEQ01_RS02350	COG0587	DNA-directed DNA polymerase activity
CEQ01_RS02355	COG0205	6-phosphofructokinase activity
CEQ01_RS02365	COG0583	DNA-binding transcription factor activity
CEQ01_RS02375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEQ01_RS02380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CEQ01_RS02385	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS02390	COG5002	protein histidine kinase activity
CEQ01_RS02495	COG3711	transcriptional antiterminator
CEQ01_RS02505	COG1263	PTS System
CEQ01_RS02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS02505	COG2190	(PTS) system
CEQ01_RS02510	COG1486	melibiose metabolic process
CEQ01_RS02515	COG2190	(PTS) system
CEQ01_RS02515	COG1263	PTS System
CEQ01_RS02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS02545	COG1349	DNA-binding transcription factor activity
CEQ01_RS02570	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ01_RS02575	COG3623	hexulose-6-phosphate isomerase
CEQ01_RS02585	COG0456	acetyltransferase
CEQ01_RS02610	COG3328	transposase activity
CEQ01_RS02615	COG3711	transcriptional antiterminator
CEQ01_RS02645	COG3964	amidohydrolase
CEQ01_RS02660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS02660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS02660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS02665	COG3711	transcriptional antiterminator
CEQ01_RS02665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS02670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ01_RS02675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEQ01_RS02680	COG0789	Transcriptional regulator
CEQ01_RS02695	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ01_RS02700	COG1349	DNA-binding transcription factor activity
CEQ01_RS02705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS02715	COG3775	system Galactitol-specific IIC component
CEQ01_RS02730	COG0400	carboxylic ester hydrolase activity
CEQ01_RS02735	COG0346	lactoylglutathione lyase activity
CEQ01_RS02745	COG2188	Transcriptional regulator
CEQ01_RS02750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS02755	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS02760	COG0589	response to stress
CEQ01_RS02775	COG1393	Belongs to the ArsC family
CEQ01_RS02785	COG0351	phosphomethylpyrimidine kinase
CEQ01_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ01_RS02795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEQ01_RS02805	COG3425	synthase
CEQ01_RS02810	COG0183	Belongs to the thiolase family
CEQ01_RS02825	COG0656	L-ascorbic acid biosynthetic process
CEQ01_RS02845	COG0392	lysyltransferase activity
CEQ01_RS02845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEQ01_RS02850	COG0596	Alpha beta hydrolase
CEQ01_RS02855	COG0741	lytic transglycosylase activity
CEQ01_RS02865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEQ01_RS02870	COG0358	DNA primase activity
CEQ01_RS02875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ01_RS02885	COG2996	Protein conserved in bacteria
CEQ01_RS02890	COG0735	belongs to the Fur family
CEQ01_RS02895	COG4974	Belongs to the 'phage' integrase family
CEQ01_RS02905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEQ01_RS02910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEQ01_RS02915	COG1187	pseudouridine synthase activity
CEQ01_RS02920	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CEQ01_RS02925	COG1288	antiporter activity
CEQ01_RS02930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ01_RS02950	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ01_RS02960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ01_RS02965	COG0539	negative regulation of cytoplasmic translation
CEQ01_RS02970	COG1160	GTP binding
CEQ01_RS02975	COG0776	regulation of translation
CEQ01_RS02990	COG0457	Tetratricopeptide repeat
CEQ01_RS02995	COG5582	Belongs to the UPF0302 family
CEQ01_RS03000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ01_RS03005	COG1694	Mazg nucleotide pyrophosphohydrolase
CEQ01_RS03010	COG0617	tRNA 3'-terminal CCA addition
CEQ01_RS03025	COG0025	NhaP-type Na H and K H
CEQ01_RS03030	COG0488	(ABC) transporter
CEQ01_RS03035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ01_RS03045	COG1272	protein, Hemolysin III
CEQ01_RS03050	COG1307	EDD domain protein, DegV family
CEQ01_RS03055	COG2755	lipolytic protein G-D-S-L family
CEQ01_RS03060	COG4698	Protein conserved in bacteria
CEQ01_RS03070	COG4479	Belongs to the UPF0346 family
CEQ01_RS03075	COG0681	Belongs to the peptidase S26 family
CEQ01_RS03095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEQ01_RS03100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEQ01_RS03105	COG0758	DNA mediated transformation
CEQ01_RS03110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ01_RS03115	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CEQ01_RS03120	COG4974	Belongs to the 'phage' integrase family
CEQ01_RS03125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEQ01_RS03130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEQ01_RS03145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEQ01_RS03150	COG1832	CoA-binding protein
CEQ01_RS03155	COG0187	DNA topoisomerase II activity
CEQ01_RS03165	COG1882	Formate acetyltransferase
CEQ01_RS03170	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ01_RS03175	COG1227	inorganic diphosphatase activity
CEQ01_RS03195	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CEQ01_RS03205	COG1073	alpha beta
CEQ01_RS03210	COG1609	Transcriptional regulator
CEQ01_RS03220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ01_RS03240	COG1732	Glycine betaine
CEQ01_RS03255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEQ01_RS03265	COG1116	anion transmembrane transporter activity
CEQ01_RS03270	COG0084	hydrolase, TatD family'
CEQ01_RS03275	COG3942	CHAP domain
CEQ01_RS03275	COG1388	LysM domain
CEQ01_RS03290	COG0346	lactoylglutathione lyase activity
CEQ01_RS03305	COG0436	Aminotransferase
CEQ01_RS03325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ01_RS03330	COG4565	transcriptional regulatory protein
CEQ01_RS03335	COG3290	protein histidine kinase activity
CEQ01_RS03345	COG2268	Band 7 protein
CEQ01_RS03370	COG0673	inositol 2-dehydrogenase activity
CEQ01_RS03380	COG1876	peptidase activity
CEQ01_RS03385	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ01_RS03385	COG1388	LysM domain
CEQ01_RS03395	COG1653	transport
CEQ01_RS03400	COG1175	transmembrane transport
CEQ01_RS03405	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS03415	COG0673	inositol 2-dehydrogenase activity
CEQ01_RS03420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ01_RS03425	COG2233	PERMEase
CEQ01_RS03435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEQ01_RS03440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEQ01_RS03445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEQ01_RS03455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEQ01_RS03460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ01_RS03465	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ01_RS03470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ01_RS03480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ01_RS03485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEQ01_RS03490	COG0138	bifunctional purine biosynthesis protein purh
CEQ01_RS03495	COG0151	Belongs to the GarS family
CEQ01_RS03500	COG4989	oxidoreductase activity
CEQ01_RS03510	COG2972	Histidine kinase
CEQ01_RS03520	COG4213	ABC transporter substrate-binding protein
CEQ01_RS03530	COG4214	carbohydrate transport
CEQ01_RS03535	COG0516	GMP reductase activity
CEQ01_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ01_RS03560	COG0022	dehydrogenase e1 component
CEQ01_RS03575	COG4476	Belongs to the UPF0223 family
CEQ01_RS03580	COG0483	inositol monophosphate 1-phosphatase activity
CEQ01_RS03585	COG1217	gtp-binding protein TYPA
CEQ01_RS03590	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ01_RS03595	COG4838	Belongs to the UPF0358 family
CEQ01_RS03600	COG0772	Belongs to the SEDS family
CEQ01_RS03605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CEQ01_RS03620	COG4471	UPF0298 protein
CEQ01_RS03625	COG0742	ribosomal rna small subunit methyltransferase
CEQ01_RS03630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ01_RS03635	COG3480	Lon protease (S16) C-terminal proteolytic domain
CEQ01_RS03655	COG2131	deaminase
CEQ01_RS03665	COG2333	competence protein COMEC
CEQ01_RS03665	COG0658	competence protein
CEQ01_RS03670	COG1466	dna polymerase III delta subunit
CEQ01_RS03675	COG0268	Binds directly to 16S ribosomal RNA
CEQ01_RS03685	COG2707	UPF0756 membrane protein
CEQ01_RS03690	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS03695	COG1968	undecaprenyl-diphosphatase activity
CEQ01_RS03715	COG1666	GTP binding
CEQ01_RS03720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ01_RS03725	COG2151	metal-sulfur cluster biosynthetic enzyme
CEQ01_RS03740	COG1388	LysM domain
CEQ01_RS03740	COG3942	CHAP domain
CEQ01_RS03795	COG4990	cell redox homeostasis
CEQ01_RS03800	COG3328	transposase activity
CEQ01_RS03820	COG3104	oligopeptide transport
CEQ01_RS03825	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CEQ01_RS03830	COG1074	ATP-dependent DNA helicase activity
CEQ01_RS03835	COG1733	regulation of RNA biosynthetic process
CEQ01_RS03840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEQ01_RS03845	COG0072	phenylalanine-tRNA ligase activity
CEQ01_RS03845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ01_RS03855	COG1126	abc transporter atp-binding protein
CEQ01_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ01_RS03865	COG0765	amino acid transport
CEQ01_RS03870	COG0765	amino acid transport
CEQ01_RS03875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEQ01_RS03880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEQ01_RS03890	COG0517	IMP dehydrogenase activity
CEQ01_RS03895	COG0668	transmembrane transport
CEQ01_RS03905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ01_RS03910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ01_RS03915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ01_RS03920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ01_RS03945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEQ01_RS03955	COG1234	tRNA 3'-trailer cleavage
CEQ01_RS03960	COG0300	oxidoreductase activity
CEQ01_RS03965	COG5416	Lipopolysaccharide assembly protein A domain
CEQ01_RS03970	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CEQ01_RS03970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ01_RS03975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ01_RS03985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEQ01_RS03990	COG4224	UPF0291 protein
CEQ01_RS04000	COG1388	LysM domain
CEQ01_RS04000	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ01_RS04005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ01_RS04010	COG0735	belongs to the Fur family
CEQ01_RS04015	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ01_RS04025	COG1846	Transcriptional regulator
CEQ01_RS04035	COG3935	DnaD domain protein
CEQ01_RS04040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ01_RS04045	COG3328	transposase activity
CEQ01_RS04060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ01_RS04065	COG3331	DNA recombination
CEQ01_RS04070	COG4474	Belongs to the UPF0398 family
CEQ01_RS04075	COG3599	regulation of cell shape
CEQ01_RS04085	COG0116	Belongs to the methyltransferase superfamily
CEQ01_RS04090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEQ01_RS04095	COG1418	mRNA catabolic process
CEQ01_RS04110	COG0156	8-amino-7-oxononanoate synthase activity
CEQ01_RS04115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEQ01_RS04120	COG0531	amino acid
CEQ01_RS04135	COG0513	Belongs to the DEAD box helicase family
CEQ01_RS04150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ01_RS04155	COG4684	Psort location CytoplasmicMembrane, score
CEQ01_RS04165	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ01_RS04175	COG1278	Cold shock
CEQ01_RS04180	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEQ01_RS04195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEQ01_RS04200	COG0564	pseudouridine synthase activity
CEQ01_RS04210	COG2233	PERMEase
CEQ01_RS04215	COG0540	Belongs to the ATCase OTCase family
CEQ01_RS04220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CEQ01_RS04225	COG0505	Belongs to the CarA family
CEQ01_RS04230	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ01_RS04235	COG0543	2 iron, 2 sulfur cluster binding
CEQ01_RS04245	COG0284	orotidine-5'-phosphate decarboxylase activity
CEQ01_RS04275	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CEQ01_RS04290	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEQ01_RS04300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ01_RS04335	COG0039	L-malate dehydrogenase activity
CEQ01_RS04355	COG3037	sugar-specific permease SgaT UlaA
CEQ01_RS04365	COG3711	transcriptional antiterminator
CEQ01_RS04375	COG0673	inositol 2-dehydrogenase activity
CEQ01_RS04425	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS04430	COG5002	protein histidine kinase activity
CEQ01_RS04435	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CEQ01_RS04445	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ01_RS04450	COG0351	phosphomethylpyrimidine kinase
CEQ01_RS04460	COG4475	Protein of unknown function (DUF436)
CEQ01_RS04465	COG0366	Alpha amylase catalytic
CEQ01_RS04480	COG1307	EDD domain protein, DegV family
CEQ01_RS04485	COG2244	polysaccharide biosynthetic process
CEQ01_RS04540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ01_RS04545	COG0194	GDP metabolic process
CEQ01_RS04565	COG0765	amino acid transport
CEQ01_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ01_RS04580	COG0167	dihydroorotate dehydrogenase activity
CEQ01_RS04590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ01_RS04600	COG3833	ABC-type maltose transport systems, permease component
CEQ01_RS04605	COG1175	transmembrane transport
CEQ01_RS04610	COG2182	Extracellular solute-binding protein
CEQ01_RS04615	COG0366	Alpha amylase catalytic
CEQ01_RS04620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ01_RS04630	COG1764	response to oxidative stress
CEQ01_RS04635	COG1846	Transcriptional regulator
CEQ01_RS04640	COG0628	permease
CEQ01_RS04665	COG1312	Catalyzes the dehydration of D-mannonate
CEQ01_RS04670	COG0246	Mannitol dehydrogenase
CEQ01_RS04680	COG0450	alkyl hydroperoxide reductase
CEQ01_RS04705	COG0768	penicillin binding
CEQ01_RS04725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEQ01_RS04740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEQ01_RS04755	COG0531	amino acid
CEQ01_RS04760	COG0004	ammonium transporteR
CEQ01_RS04770	COG2261	transglycosylase associated protein
CEQ01_RS04795	COG3655	Transcriptional regulator
CEQ01_RS04805	COG2261	transglycosylase associated protein
CEQ01_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ01_RS04840	COG1442	glycosyl transferase family 8
CEQ01_RS04845	COG1442	glycosyl transferase family 8
CEQ01_RS04850	COG0561	phosphatase activity
CEQ01_RS04875	COG1476	TRANSCRIPTIONal
CEQ01_RS04895	COG1278	Cold shock
CEQ01_RS04900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS04905	COG1312	Catalyzes the dehydration of D-mannonate
CEQ01_RS04920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS04925	COG3716	PTS system mannose fructose sorbose family IID component
CEQ01_RS04935	COG0371	Dehydrogenase
CEQ01_RS04945	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CEQ01_RS04955	COG0837	glucose binding
CEQ01_RS04955	COG1737	Transcriptional regulator
CEQ01_RS05010	COG3730	PTS system glucitol sorbitol-specific
CEQ01_RS05080	COG0640	Transcriptional regulator
CEQ01_RS05085	COG1278	Cold shock
CEQ01_RS05100	COG3328	transposase activity
CEQ01_RS05110	COG0481	GTPase activity
CEQ01_RS05130	COG0542	response to heat
CEQ01_RS05150	COG1597	lipid kinase activity
CEQ01_RS05155	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ01_RS05160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEQ01_RS05165	COG2384	SAM-dependent methyltransferase
CEQ01_RS05175	COG1484	DNA-dependent DNA replication
CEQ01_RS05185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEQ01_RS05195	COG0237	dephospho-CoA kinase activity
CEQ01_RS05200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEQ01_RS05205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ01_RS05205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ01_RS05220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ01_RS05225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEQ01_RS05230	COG3091	SprT-like family
CEQ01_RS05235	COG2183	response to ionizing radiation
CEQ01_RS05245	COG1054	Belongs to the UPF0176 family
CEQ01_RS05270	COG0546	phosphoglycolate phosphatase activity
CEQ01_RS05275	COG0588	phosphoglycerate mutase activity
CEQ01_RS05320	COG2207	Transcriptional regulator
CEQ01_RS05320	COG4753	response regulator
CEQ01_RS05325	COG2972	Histidine kinase
CEQ01_RS05330	COG0077	Prephenate dehydratase
CEQ01_RS05335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ01_RS05340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEQ01_RS05345	COG0287	Prephenate dehydrogenase
CEQ01_RS05350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ01_RS05360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CEQ01_RS05370	COG3250	beta-galactosidase activity
CEQ01_RS05385	COG1609	Transcriptional regulator
CEQ01_RS05395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ01_RS05405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ01_RS05410	COG1597	lipid kinase activity
CEQ01_RS05415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEQ01_RS05420	COG0154	amidase activity
CEQ01_RS05425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEQ01_RS05430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEQ01_RS05435	COG0210	DNA helicase
CEQ01_RS05445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS05445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS05445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ01_RS05450	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ01_RS05455	COG1349	DNA-binding transcription factor activity
CEQ01_RS05470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEQ01_RS05475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEQ01_RS05480	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ01_RS05490	COG1714	RDD family
CEQ01_RS05505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ01_RS05510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ01_RS05550	COG1481	regulation of sporulation
CEQ01_RS05555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEQ01_RS05560	COG1660	Displays ATPase and GTPase activities
CEQ01_RS05575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ01_RS05580	COG0556	nucleotide-excision repair
CEQ01_RS05585	COG0765	amino acid transport
CEQ01_RS05590	COG1126	abc transporter atp-binding protein
CEQ01_RS05595	COG0484	heat shock protein binding
CEQ01_RS05600	COG0443	Heat shock 70 kDa protein
CEQ01_RS05605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ01_RS05610	COG1420	regulation of RNA biosynthetic process
CEQ01_RS05615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ01_RS05640	COG3328	transposase activity
CEQ01_RS05645	COG0693	protein deglycase activity
CEQ01_RS05655	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEQ01_RS05665	COG5646	InterPro IPR014922
CEQ01_RS05675	COG4975	Glucose uptake
CEQ01_RS05685	COG0196	riboflavin kinase activity
CEQ01_RS05690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEQ01_RS05695	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEQ01_RS05700	COG1175	transmembrane transport
CEQ01_RS05705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEQ01_RS05720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CEQ01_RS05725	COG0195	Participates in both transcription termination and antitermination
CEQ01_RS05730	COG0779	Required for maturation of 30S ribosomal subunits
CEQ01_RS05735	COG2176	DNA-directed DNA polymerase activity
CEQ01_RS05740	COG0442	prolyl-tRNA aminoacylation
CEQ01_RS05745	COG0750	zinc metalloprotease
CEQ01_RS05750	COG4589	Belongs to the CDS family
CEQ01_RS05755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ01_RS05760	COG0233	cytoplasmic translational termination
CEQ01_RS05765	COG0528	UMP kinase activity
CEQ01_RS05770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ01_RS05775	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ01_RS05780	COG1438	arginine binding
CEQ01_RS05800	COG0018	arginyl-trna synthetase
CEQ01_RS05815	COG2235	arginine
CEQ01_RS05820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ01_RS05825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEQ01_RS05830	COG0456	acetyltransferase
CEQ01_RS05840	COG1214	PFAM Peptidase M22, glycoprotease
CEQ01_RS05845	COG1609	Transcriptional regulator
CEQ01_RS05850	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CEQ01_RS05855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ01_RS05870	COG3189	MarR family transcriptional regulator
CEQ01_RS05875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ01_RS05880	COG1940	carbohydrate kinase activity
CEQ01_RS05895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ01_RS05900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ01_RS05905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ01_RS05910	COG1120	ATPase activity
CEQ01_RS05925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ01_RS05930	COG4876	unkown
CEQ01_RS05935	COG0367	asparagine synthase
CEQ01_RS05940	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CEQ01_RS05965	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ01_RS05970	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ01_RS06045	COG0740	serine-type endopeptidase activity
CEQ01_RS06235	COG1309	transcriptional regulator
CEQ01_RS06255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEQ01_RS06265	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ01_RS06280	COG0166	Belongs to the GPI family
CEQ01_RS06285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEQ01_RS06290	COG2081	HI0933 family
CEQ01_RS06295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ01_RS06300	COG0710	3-dehydroquinate dehydratase activity
CEQ01_RS06305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ01_RS06310	COG1368	sulfuric ester hydrolase activity
CEQ01_RS06330	COG3850	Histidine kinase
CEQ01_RS06330	COG5002	protein histidine kinase activity
CEQ01_RS06335	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS06385	COG1956	GAF domain-containing protein
CEQ01_RS06390	COG3527	Alpha-acetolactate decarboxylase
CEQ01_RS06395	COG0028	Belongs to the TPP enzyme family
CEQ01_RS06405	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS06410	COG1175	transmembrane transport
CEQ01_RS06445	COG0335	large ribosomal subunit rRNA binding
CEQ01_RS06450	COG0336	Belongs to the RNA methyltransferase TrmD family
CEQ01_RS06455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEQ01_RS06465	COG1837	Belongs to the UPF0109 family
CEQ01_RS06470	COG0228	four-way junction DNA binding
CEQ01_RS06475	COG0431	NADPH-dependent FMN reductase
CEQ01_RS06480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CEQ01_RS06485	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ01_RS06490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ01_RS06495	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CEQ01_RS06505	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS06510	COG5002	protein histidine kinase activity
CEQ01_RS06515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEQ01_RS06520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ01_RS06565	COG0714	Associated with various cellular activities
CEQ01_RS06580	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS06585	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS06590	COG2608	mercury ion transmembrane transporter activity
CEQ01_RS06595	COG3682	Transcriptional regulator
CEQ01_RS06610	COG0531	amino acid
CEQ01_RS06615	COG2217	Heavy metal translocating P-type atpase
CEQ01_RS06640	COG0017	Asparaginyl-tRNA synthetase
CEQ01_RS06645	COG0436	Aminotransferase
CEQ01_RS06655	COG1199	ATP-dependent helicase activity
CEQ01_RS06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ01_RS06660	COG1278	Cold shock
CEQ01_RS06680	COG1686	Belongs to the peptidase S11 family
CEQ01_RS06690	COG0038	chloride channel
CEQ01_RS06710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ01_RS06715	COG1254	Belongs to the acylphosphatase family
CEQ01_RS06725	COG0706	membrane insertase activity
CEQ01_RS06745	COG1216	Glycosyl transferase, family 2
CEQ01_RS06745	COG1442	glycosyl transferase family 8
CEQ01_RS06765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ01_RS06770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEQ01_RS06775	COG4464	protein tyrosine phosphatase activity
CEQ01_RS06780	COG0489	protein tyrosine kinase activity
CEQ01_RS06785	COG3944	biosynthesis protein
CEQ01_RS06790	COG1316	TRANSCRIPTIONal
CEQ01_RS06800	COG0751	glycine-tRNA ligase activity
CEQ01_RS06805	COG0752	glycyl-tRNA synthetase alpha subunit
CEQ01_RS06810	COG1381	Involved in DNA repair and RecF pathway recombination
CEQ01_RS06815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEQ01_RS06820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ01_RS06825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEQ01_RS06835	COG1702	phosphate starvation-inducible protein PhoH
CEQ01_RS06840	COG1114	Component of the transport system for branched-chain amino acids
CEQ01_RS06845	COG1610	YqeY-like protein
CEQ01_RS06850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEQ01_RS06855	COG0735	belongs to the Fur family
CEQ01_RS06860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEQ01_RS06865	COG0640	Transcriptional regulator
CEQ01_RS06870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ01_RS06875	COG0492	ferredoxin-NADP+ reductase activity
CEQ01_RS06880	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS06885	COG1486	melibiose metabolic process
CEQ01_RS06905	COG3711	transcriptional antiterminator
CEQ01_RS06910	COG1132	(ABC) transporter
CEQ01_RS06915	COG1132	(ABC) transporter
CEQ01_RS06920	COG3763	UPF0154 protein
CEQ01_RS06925	COG1914	H( )-stimulated, divalent metal cation uptake system
CEQ01_RS06935	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEQ01_RS06950	COG1609	Transcriptional regulator
CEQ01_RS06960	COG4980	gas vesicle protein
CEQ01_RS06970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEQ01_RS06975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ01_RS06980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEQ01_RS06985	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEQ01_RS06990	COG1950	PFAM Membrane protein of
CEQ01_RS07020	COG0704	Plays a role in the regulation of phosphate uptake
CEQ01_RS07025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ01_RS07030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ01_RS07035	COG0581	inorganic phosphate transmembrane transporter activity
CEQ01_RS07040	COG0573	inorganic phosphate transmembrane transporter activity
CEQ01_RS07045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ01_RS07050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ01_RS07055	COG2177	Part of the ABC transporter FtsEX involved in
CEQ01_RS07060	COG2884	Cell division ATP-binding protein ftsE
CEQ01_RS07070	COG0653	protein targeting
CEQ01_RS07085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CEQ01_RS07090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS07100	COG1739	Uncharacterized protein family UPF0029
CEQ01_RS07105	COG2188	Transcriptional regulator
CEQ01_RS07125	COG1940	carbohydrate kinase activity
CEQ01_RS07145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ01_RS07155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ01_RS07160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ01_RS07165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ01_RS07170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ01_RS07175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ01_RS07180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ01_RS07185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ01_RS07190	COG0356	it plays a direct role in the translocation of protons across the membrane
CEQ01_RS07195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEQ01_RS07200	COG0557	exoribonuclease II activity
CEQ01_RS07210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ01_RS07215	COG2388	GCN5-related N-acetyl-transferase
CEQ01_RS07235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ01_RS07245	COG0149	triose-phosphate isomerase activity
CEQ01_RS07250	COG0126	phosphoglycerate kinase activity
CEQ01_RS07260	COG2390	Transcriptional regulator
CEQ01_RS07265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CEQ01_RS07295	COG3290	protein histidine kinase activity
CEQ01_RS07300	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS07305	COG0726	polysaccharide deacetylase
CEQ01_RS07315	COG1595	DNA-templated transcription, initiation
CEQ01_RS07330	COG0095	Lipoate-protein ligase
CEQ01_RS07335	COG1078	dGTPase activity
CEQ01_RS07340	COG0561	phosphatase activity
CEQ01_RS07345	COG0494	nUDIX hydrolase
CEQ01_RS07350	COG0346	lactoylglutathione lyase activity
CEQ01_RS07360	COG2423	ornithine cyclodeaminase activity
CEQ01_RS07365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ01_RS07370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ01_RS07375	COG1394	ATPase activity, coupled to movement of substances
CEQ01_RS07380	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CEQ01_RS07385	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CEQ01_RS07390	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
CEQ01_RS07395	COG1527	subunit (C
CEQ01_RS07400	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CEQ01_RS07405	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ01_RS07410	COG1269	ATP hydrolysis coupled proton transport
CEQ01_RS07420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CEQ01_RS07425	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CEQ01_RS07435	COG4152	abc transporter atp-binding protein
CEQ01_RS07440	COG0322	excinuclease ABC activity
CEQ01_RS07445	COG3118	belongs to the thioredoxin family
CEQ01_RS07450	COG1193	negative regulation of DNA recombination
CEQ01_RS07465	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEQ01_RS07480	COG1136	(ABC) transporter
CEQ01_RS07530	COG1304	FMN binding
CEQ01_RS07540	COG0281	malic enzyme
CEQ01_RS07560	COG3906	Belongs to the UPF0473 family
CEQ01_RS07565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ01_RS07570	COG4472	Bacterial protein of unknown function (DUF965)
CEQ01_RS07600	COG3689	TIGRFAM TIGR03943 family protein
CEQ01_RS07605	COG0701	Predicted permease
CEQ01_RS07615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CEQ01_RS07620	COG0488	(ABC) transporter
CEQ01_RS07655	COG1070	Carbohydrate kinase
CEQ01_RS07665	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ01_RS07670	COG1129	ABC transporter
CEQ01_RS07675	COG3507	Belongs to the glycosyl hydrolase 43 family
CEQ01_RS07680	COG2115	Belongs to the xylose isomerase family
CEQ01_RS07695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ01_RS07700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ01_RS07705	COG1177	transmembrane transport
CEQ01_RS07710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ01_RS07715	COG3842	ATPase activity
CEQ01_RS07725	COG0604	alcohol dehydrogenase
CEQ01_RS07730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ01_RS07735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ01_RS07740	COG4684	Psort location CytoplasmicMembrane, score
CEQ01_RS07745	COG0702	epimerase
CEQ01_RS07750	COG0604	alcohol dehydrogenase
CEQ01_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ01_RS07750	COG3321	synthase
CEQ01_RS07760	COG1053	succinate dehydrogenase
CEQ01_RS07780	COG3328	transposase activity
CEQ01_RS07790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ01_RS07800	COG0708	Exodeoxyribonuclease III
CEQ01_RS07810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ01_RS07815	COG0802	atpase or kinase
CEQ01_RS07820	COG0280	phosphate acetyltransferase
CEQ01_RS07825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ01_RS07830	COG0561	phosphatase activity
CEQ01_RS07855	COG0346	lactoylglutathione lyase activity
CEQ01_RS07870	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CEQ01_RS07890	COG1131	(ABC) transporter
CEQ01_RS07895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CEQ01_RS07910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS07910	COG1263	PTS System
CEQ01_RS07915	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ01_RS07930	COG0488	(ABC) transporter
CEQ01_RS07935	COG1929	Belongs to the glycerate kinase type-1 family
CEQ01_RS07940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ01_RS07950	COG1113	amino acid transport
CEQ01_RS07970	COG1757	Na H antiporter
CEQ01_RS07980	COG1464	Belongs to the NlpA lipoprotein family
CEQ01_RS07985	COG2011	ABC-type metal ion transport system permease component
CEQ01_RS07990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ01_RS08000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS08005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEQ01_RS08010	COG0105	UTP biosynthetic process
CEQ01_RS08020	COG1368	sulfuric ester hydrolase activity
CEQ01_RS08040	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS08055	COG1428	Deoxynucleoside kinase
CEQ01_RS08065	COG1611	Belongs to the LOG family
CEQ01_RS08090	COG2188	Transcriptional regulator
CEQ01_RS08095	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS08100	COG1263	PTS System
CEQ01_RS08100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS08100	COG2190	(PTS) system
CEQ01_RS08105	COG3711	transcriptional antiterminator
CEQ01_RS08110	COG3764	Sortase (surface protein transpeptidase)
CEQ01_RS08155	COG1597	lipid kinase activity
CEQ01_RS08165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ01_RS08190	COG0719	Fe-S assembly protein
CEQ01_RS08200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ01_RS08205	COG0719	Fe-S assembly protein
CEQ01_RS08215	COG1464	Belongs to the NlpA lipoprotein family
CEQ01_RS08220	COG2011	ABC-type metal ion transport system permease component
CEQ01_RS08225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ01_RS08230	COG0509	glycine decarboxylation via glycine cleavage system
CEQ01_RS08235	COG1393	Belongs to the ArsC family
CEQ01_RS08240	COG0772	Belongs to the SEDS family
CEQ01_RS08250	COG0583	DNA-binding transcription factor activity
CEQ01_RS08265	COG2855	membrane
CEQ01_RS08270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ01_RS08275	COG0463	Glycosyl transferase, family 2
CEQ01_RS08295	COG2814	Major facilitator Superfamily
CEQ01_RS08300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ01_RS08310	COG0482	sulfurtransferase activity
CEQ01_RS08330	COG1104	cysteine desulfurase activity
CEQ01_RS08335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ01_RS08345	COG3590	peptidase
CEQ01_RS08360	COG3328	transposase activity
CEQ01_RS08365	COG1335	isochorismatase
CEQ01_RS08370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEQ01_RS08390	COG3853	Toxic anion resistance protein (TelA)
CEQ01_RS08395	COG0531	amino acid
CEQ01_RS08400	COG4975	Glucose uptake
CEQ01_RS08405	COG2205	protein histidine kinase activity
CEQ01_RS08410	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS08445	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS08450	COG1175	transmembrane transport
CEQ01_RS08460	COG3546	catalase activity
CEQ01_RS08505	COG2135	peptidase activity
CEQ01_RS08530	COG1335	isochorismatase
CEQ01_RS08535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ01_RS08540	COG1764	response to oxidative stress
CEQ01_RS08555	COG1438	arginine binding
CEQ01_RS08565	COG0477	Major facilitator Superfamily
CEQ01_RS08570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ01_RS08580	COG2823	Periplasmic or secreted lipoprotein
CEQ01_RS08580	COG1652	LysM domain
CEQ01_RS08585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ01_RS08600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ01_RS08605	COG1121	(ABC) transporter
CEQ01_RS08610	COG1113	amino acid transport
CEQ01_RS08620	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ01_RS08625	COG2207	Transcriptional regulator
CEQ01_RS08640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEQ01_RS08645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ01_RS08665	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ01_RS08670	COG0436	Aminotransferase
CEQ01_RS08675	COG1473	amidohydrolase
CEQ01_RS08680	COG0527	aspartate kinase activity
CEQ01_RS08685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ01_RS08690	COG2171	N-acyltransferase activity
CEQ01_RS08695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEQ01_RS08705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEQ01_RS08710	COG0019	diaminopimelate decarboxylase activity
CEQ01_RS08715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ01_RS08730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ01_RS08735	COG0626	cystathionine gamma-synthase activity
CEQ01_RS08740	COG1854	S-ribosylhomocysteine lyase activity
CEQ01_RS08745	COG0386	Belongs to the glutathione peroxidase family
CEQ01_RS08770	COG1393	Belongs to the ArsC family
CEQ01_RS08775	COG1393	Belongs to the ArsC family
CEQ01_RS08780	COG0210	DNA helicase
CEQ01_RS08795	COG1428	Deoxynucleoside kinase
CEQ01_RS08820	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEQ01_RS08820	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEQ01_RS08825	COG0628	permease
CEQ01_RS08835	COG0366	Alpha amylase catalytic
CEQ01_RS08855	COG1609	Transcriptional regulator
CEQ01_RS08865	COG1869	D-ribose catabolic process
CEQ01_RS08870	COG1263	PTS System
CEQ01_RS08870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS08870	COG2190	(PTS) system
CEQ01_RS08875	COG3942	CHAP domain
CEQ01_RS08875	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ01_RS08890	COG1136	(ABC) transporter
CEQ01_RS08925	COG1811	Na channel or pump
CEQ01_RS08945	COG1136	(ABC) transporter
CEQ01_RS08945	COG0577	efflux transmembrane transporter activity
CEQ01_RS08955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEQ01_RS08960	COG0163	prenyltransferase activity
CEQ01_RS08990	COG2814	Major facilitator Superfamily
CEQ01_RS09000	COG1695	Transcriptional regulator
CEQ01_RS09005	COG3479	Phenolic acid decarboxylase
CEQ01_RS09035	COG1263	PTS System
CEQ01_RS09035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS09035	COG2190	(PTS) system
CEQ01_RS09045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS09055	COG1609	Transcriptional regulator
CEQ01_RS09060	COG1757	Na H antiporter
CEQ01_RS09065	COG0531	amino acid
CEQ01_RS09085	COG1309	transcriptional regulator
CEQ01_RS09095	COG1131	(ABC) transporter
CEQ01_RS09105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ01_RS09120	COG1461	Dihydroxyacetone kinase
CEQ01_RS09125	COG2376	Dihydroxyacetone kinase
CEQ01_RS09130	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CEQ01_RS09155	COG3973	AAA domain
CEQ01_RS09160	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ01_RS09165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ01_RS09170	COG1937	Protein conserved in bacteria
CEQ01_RS09190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ01_RS09195	COG1193	negative regulation of DNA recombination
CEQ01_RS09200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ01_RS09205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ01_RS09210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEQ01_RS09220	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ01_RS09230	COG1902	pentaerythritol trinitrate reductase activity
CEQ01_RS09245	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS09250	COG2190	(PTS) system
CEQ01_RS09250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS09250	COG1263	PTS System
CEQ01_RS09260	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS09265	COG0366	Alpha amylase catalytic
CEQ01_RS09280	COG2252	PERMEase
CEQ01_RS09305	COG1846	Transcriptional regulator
CEQ01_RS09310	COG1051	belongs to the nudix hydrolase family
CEQ01_RS09380	COG3052	prosthetic group binding
CEQ01_RS09390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEQ01_RS09420	COG1113	amino acid transport
CEQ01_RS09465	COG4716	Myosin-crossreactive antigen
CEQ01_RS09475	COG1063	alcohol dehydrogenase
CEQ01_RS09490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS09495	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEQ01_RS09505	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS09510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS09515	COG2186	Transcriptional regulator
CEQ01_RS09520	COG0667	Aldo Keto reductase
CEQ01_RS09550	COG0101	tRNA pseudouridine synthase activity
CEQ01_RS09560	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEQ01_RS09565	COG1368	sulfuric ester hydrolase activity
CEQ01_RS09625	COG1764	response to oxidative stress
CEQ01_RS09640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ01_RS09650	COG4807	Protein conserved in bacteria
CEQ01_RS09655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ01_RS09660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ01_RS09665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ01_RS09670	COG0589	response to stress
CEQ01_RS09675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ01_RS09680	COG1363	Peptidase, m42
CEQ01_RS09700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEQ01_RS09705	COG0824	Thioesterase
CEQ01_RS09740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEQ01_RS09745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEQ01_RS09750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEQ01_RS09765	COG1428	Deoxynucleoside kinase
CEQ01_RS09770	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CEQ01_RS09785	COG1304	FMN binding
CEQ01_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ01_RS09795	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CEQ01_RS09805	COG0800	Aldolase
CEQ01_RS09810	COG1414	Transcriptional regulator
CEQ01_RS09815	COG1454	alcohol dehydrogenase
CEQ01_RS09820	COG3254	rhamnose metabolic process
CEQ01_RS09825	COG0235	Class ii aldolase
CEQ01_RS09830	COG4806	L-rhamnose isomerase
CEQ01_RS09835	COG1070	Carbohydrate kinase
CEQ01_RS09840	COG2207	Transcriptional regulator
CEQ01_RS09840	COG1917	Cupin 2, conserved barrel domain protein
CEQ01_RS09870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEQ01_RS09875	COG1454	alcohol dehydrogenase
CEQ01_RS09875	COG1012	belongs to the aldehyde dehydrogenase family
CEQ01_RS09885	COG1862	Preprotein translocase
CEQ01_RS09890	COG0343	queuine tRNA-ribosyltransferase activity
CEQ01_RS09905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEQ01_RS09925	COG1174	glycine betaine transport
CEQ01_RS09955	COG0531	amino acid
CEQ01_RS09970	COG0604	alcohol dehydrogenase
CEQ01_RS09970	COG3321	synthase
CEQ01_RS09975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ01_RS09985	COG2337	Toxic component of a toxin-antitoxin (TA) module
CEQ01_RS09990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ01_RS09995	COG0736	holo-[acyl-carrier-protein] synthase activity
CEQ01_RS10005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ01_RS10010	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ01_RS10020	COG1671	Belongs to the UPF0178 family
CEQ01_RS10045	COG0572	uridine kinase
CEQ01_RS10050	COG1011	Hydrolase
CEQ01_RS10055	COG1187	pseudouridine synthase activity
CEQ01_RS10060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEQ01_RS10070	COG0534	Mate efflux family protein
CEQ01_RS10075	COG1253	flavin adenine dinucleotide binding
CEQ01_RS10080	COG3158	transport of potassium into the cell
CEQ01_RS10095	COG1185	polyribonucleotide nucleotidyltransferase activity
CEQ01_RS10100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEQ01_RS10105	COG0242	peptide deformylase activity
CEQ01_RS10115	COG1827	regulation of RNA biosynthetic process
CEQ01_RS10120	COG0110	maltose O-acetyltransferase activity
CEQ01_RS10125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ01_RS10140	COG0765	amino acid transport
CEQ01_RS10145	COG1126	abc transporter atp-binding protein
CEQ01_RS10150	COG1113	amino acid transport
CEQ01_RS10160	COG1114	Component of the transport system for branched-chain amino acids
CEQ01_RS10170	COG3328	transposase activity
CEQ01_RS10180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ01_RS10190	COG2255	four-way junction helicase activity
CEQ01_RS10195	COG0632	four-way junction helicase activity
CEQ01_RS10205	COG2188	Transcriptional regulator
CEQ01_RS10210	COG1263	PTS System
CEQ01_RS10210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS10215	COG0424	maF-like protein
CEQ01_RS10225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ01_RS10235	COG1692	metallophosphoesterase
CEQ01_RS10245	COG0561	phosphatase activity
CEQ01_RS10260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ01_RS10265	COG1268	BioY protein
CEQ01_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ01_RS10295	COG1380	Effector of murein hydrolase LrgA
CEQ01_RS10315	COG3328	transposase activity
CEQ01_RS10325	COG4932	domain protein
CEQ01_RS10325	COG4886	Leucine-rich repeat (LRR) protein
CEQ01_RS10350	COG4607	ABC-type enterochelin transport system periplasmic component
CEQ01_RS10355	COG4604	ABC transporter, ATP-binding protein
CEQ01_RS10360	COG4605	iron ion homeostasis
CEQ01_RS10365	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ01_RS10375	COG2918	glutathione biosynthetic process
CEQ01_RS10375	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ01_RS10380	COG0552	protein localization to endoplasmic reticulum
CEQ01_RS10385	COG0561	phosphatase activity
CEQ01_RS10390	COG1196	nuclear chromosome segregation
CEQ01_RS10395	COG0571	ribonuclease III activity
CEQ01_RS10415	COG0601	transmembrane transport
CEQ01_RS10420	COG4608	Belongs to the ABC transporter superfamily
CEQ01_RS10430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ01_RS10435	COG0416	fatty acid biosynthetic process
CEQ01_RS10440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEQ01_RS10445	COG1461	Dihydroxyacetone kinase
CEQ01_RS10460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEQ01_RS10485	COG1522	sequence-specific DNA binding
CEQ01_RS10490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CEQ01_RS10505	COG0101	tRNA pseudouridine synthase activity
CEQ01_RS10515	COG1122	ATPase activity
CEQ01_RS10520	COG1122	ATPase activity
CEQ01_RS10525	COG0203	ribosomal protein L17
CEQ01_RS10530	COG0202	RNA polymerase activity
CEQ01_RS10535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ01_RS10540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ01_RS10545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ01_RS10550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEQ01_RS10555	COG0563	adenylate kinase activity
CEQ01_RS10560	COG0201	protein transport
CEQ01_RS10565	COG0200	Binds to the 23S rRNA
CEQ01_RS10570	COG1841	ribosomal large subunit assembly
CEQ01_RS10575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEQ01_RS10580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEQ01_RS10585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ01_RS10590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ01_RS10595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ01_RS10600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEQ01_RS10605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEQ01_RS10610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEQ01_RS10615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ01_RS10620	COG0255	Belongs to the universal ribosomal protein uL29 family
CEQ01_RS10625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEQ01_RS10630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEQ01_RS10635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEQ01_RS10645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEQ01_RS10650	COG0089	rRNA binding
CEQ01_RS10655	COG0088	Forms part of the polypeptide exit tunnel
CEQ01_RS10660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEQ01_RS10665	COG0051	transcription antitermination factor activity, RNA binding
CEQ01_RS10670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ01_RS10675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ01_RS10680	COG0049	tRNA binding
CEQ01_RS10685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEQ01_RS10690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEQ01_RS10700	COG0588	phosphoglycerate mutase activity
CEQ01_RS10710	COG0813	purine-nucleoside phosphorylase activity
CEQ01_RS10720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEQ01_RS10725	COG1079	Belongs to the binding-protein-dependent transport system permease family
CEQ01_RS10730	COG4603	Belongs to the binding-protein-dependent transport system permease family
CEQ01_RS10735	COG3845	ABC transporter
CEQ01_RS10740	COG1744	ABC transporter substrate-binding protein PnrA-like
CEQ01_RS10745	COG0295	cytidine deaminase activity
CEQ01_RS10750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEQ01_RS10755	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ01_RS10760	COG1609	Transcriptional regulator
CEQ01_RS10765	COG2813	Specifically methylates the guanine in position
CEQ01_RS10770	COG1072	(Pantothenic acid kinase))
CEQ01_RS10775	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ01_RS10775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ01_RS10785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS10785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS10795	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS10870	COG0028	Belongs to the TPP enzyme family
CEQ01_RS10880	COG0488	(ABC) transporter
CEQ01_RS10890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ01_RS10895	COG0305	Participates in initiation and elongation during chromosome replication
CEQ01_RS10900	COG0359	binds to the 23S rRNA
CEQ01_RS10910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEQ01_RS10915	COG0629	single-stranded DNA binding
CEQ01_RS10920	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ01_RS10930	COG0187	DNA topoisomerase II activity
CEQ01_RS10935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ01_RS10940	COG2501	S4 domain
CEQ01_RS10945	COG0592	DNA-directed DNA polymerase activity
CEQ01_RS10950	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEQ01_RS10960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEQ01_RS10965	COG0594	ribonuclease P activity
CEQ01_RS10970	COG0706	membrane insertase activity
CEQ01_RS10975	COG1847	R3H domain protein
CEQ01_RS10985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEQ01_RS10990	COG0445	tRNA wobble uridine modification
CEQ01_RS10995	COG0357	Ribosomal RNA small subunit methyltransferase G
CEQ01_RS11000	COG1192	Involved in chromosome partitioning
CEQ01_RS11005	COG1475	DNA binding
CEQ01_RS11010	COG4481	Protein conserved in bacteria
CEQ01_RS11015	COG0012	GTP binding
CEQ01_RS11030	COG0517	IMP dehydrogenase activity
CEQ01_RS11030	COG0516	GMP reductase activity
CEQ01_RS11040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEQ01_RS11120	COG4463	regulation of RNA biosynthetic process
CEQ01_RS11125	COG0542	response to heat
CEQ01_RS11130	COG0826	peptidase U32
CEQ01_RS11135	COG0826	peptidase U32
CEQ01_RS11140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ01_RS11155	COG4939	FMN-binding domain protein
CEQ01_RS11175	COG0142	geranyltranstransferase activity
CEQ01_RS11190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEQ01_RS11190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEQ01_RS11205	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEQ01_RS11220	COG0085	RNA polymerase activity
CEQ01_RS11225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ01_RS11230	COG1609	Transcriptional regulator
CEQ01_RS11235	COG0366	Alpha amylase catalytic
CEQ01_RS11240	COG1653	transport
CEQ01_RS11245	COG1175	transmembrane transport
CEQ01_RS11250	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS11255	COG1063	alcohol dehydrogenase
CEQ01_RS11260	COG1082	Xylose isomerase domain protein TIM barrel
CEQ01_RS11265	COG0673	inositol 2-dehydrogenase activity
CEQ01_RS11270	COG1554	hydrolase, family 65, central catalytic
CEQ01_RS11280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ01_RS11285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ01_RS11290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEQ01_RS11295	COG1070	Carbohydrate kinase
CEQ01_RS11300	COG0783	Belongs to the Dps family
CEQ01_RS11305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEQ01_RS11310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEQ01_RS11330	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS11335	COG2205	protein histidine kinase activity
CEQ01_RS11345	COG1131	(ABC) transporter
CEQ01_RS11350	COG0842	Transport permease protein
CEQ01_RS11360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ01_RS11375	COG0604	alcohol dehydrogenase
CEQ01_RS11390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CEQ01_RS11405	COG3708	Transcriptional regulator
CEQ01_RS11405	COG2207	Transcriptional regulator
CEQ01_RS11420	COG0702	epimerase
CEQ01_RS11425	COG2190	(PTS) system
CEQ01_RS11425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ01_RS11425	COG1263	PTS System
CEQ01_RS11430	COG3711	transcriptional antiterminator
CEQ01_RS11435	COG0583	DNA-binding transcription factor activity
CEQ01_RS11445	COG4221	oxidoreductase activity
CEQ01_RS11450	COG1388	LysM domain
CEQ01_RS11450	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ01_RS11460	COG0778	Nitroreductase
CEQ01_RS11490	COG2814	Major facilitator Superfamily
CEQ01_RS11505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEQ01_RS11510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEQ01_RS11515	COG0756	dUTP diphosphatase activity
CEQ01_RS11525	COG4956	integral membrane protein (PIN domain superfamily)
CEQ01_RS11530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ01_RS11535	COG1045	serine acetyltransferase
CEQ01_RS11540	COG0215	cysteine-tRNA ligase activity
CEQ01_RS11545	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CEQ01_RS11550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ01_RS11555	COG3688	RNA-binding protein containing a PIN domain
CEQ01_RS11565	COG4466	Protein conserved in bacteria
CEQ01_RS11570	COG2153	protein acetylation
CEQ01_RS11575	COG1970	mechanosensitive ion channel activity
CEQ01_RS11580	COG0612	Peptidase, M16
CEQ01_RS11585	COG0612	Peptidase, M16
CEQ01_RS11590	COG1426	Protein conserved in bacteria
CEQ01_RS11600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ01_RS11605	COG1058	Belongs to the CinA family
CEQ01_RS11605	COG1546	Belongs to the CinA family
CEQ01_RS11610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ01_RS11615	COG1418	mRNA catabolic process
CEQ01_RS11620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEQ01_RS11625	COG0392	lysyltransferase activity
CEQ01_RS11625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CEQ01_RS11630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEQ01_RS11635	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEQ01_RS11635	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEQ01_RS11640	COG1121	(ABC) transporter
CEQ01_RS11645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ01_RS11650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ01_RS11655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ01_RS11660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ01_RS11675	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ01_RS11685	COG1561	YicC-like family, N-terminal region
CEQ01_RS11695	COG0194	GDP metabolic process
CEQ01_RS11700	COG1758	RNA polymerase activity
CEQ01_RS11705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ01_RS11710	COG0242	peptide deformylase activity
CEQ01_RS11715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ01_RS11720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ01_RS11720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ01_RS11725	COG0631	protein serine/threonine phosphatase activity
CEQ01_RS11730	COG2815	serine threonine protein kinase
CEQ01_RS11730	COG0515	serine threonine protein kinase
CEQ01_RS11735	COG1162	GTPase activity
CEQ01_RS11740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEQ01_RS11750	COG1792	Involved in formation and maintenance of cell shape
CEQ01_RS11775	COG0217	transcriptional regulatory protein
CEQ01_RS11785	COG0039	L-malate dehydrogenase activity
CEQ01_RS11790	COG0193	aminoacyl-tRNA hydrolase activity
CEQ01_RS11795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ01_RS11800	COG2244	polysaccharide biosynthetic process
CEQ01_RS11805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEQ01_RS11815	COG1098	S1 RNA binding domain
CEQ01_RS11820	COG0037	tRNA processing
CEQ01_RS11825	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CEQ01_RS11835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ01_RS11840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ01_RS11845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEQ01_RS12000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ01_RS12005	COG0477	Major facilitator Superfamily
CEQ01_RS12020	COG1132	(ABC) transporter
CEQ01_RS12025	COG1132	(ABC) transporter
CEQ01_RS12030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CEQ01_RS12035	COG1242	4 iron, 4 sulfur cluster binding
CEQ01_RS12040	COG0671	phosphoesterase, PA-phosphatase related
CEQ01_RS12045	COG1388	LysM domain
CEQ01_RS12045	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ01_RS12050	COG0495	leucyl-tRNA aminoacylation
CEQ01_RS12065	COG1132	(ABC) transporter
CEQ01_RS12075	COG0789	Transcriptional regulator
CEQ01_RS12075	COG4978	Transcriptional regulator
CEQ01_RS12120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS12120	COG3711	transcriptional antiterminator
CEQ01_RS12140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ01_RS12150	COG2244	polysaccharide biosynthetic process
CEQ01_RS12155	COG1187	pseudouridine synthase activity
CEQ01_RS12165	COG1175	transmembrane transport
CEQ01_RS12170	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS12175	COG1653	transport
CEQ01_RS12190	COG2972	Histidine kinase
CEQ01_RS12195	COG2207	Transcriptional regulator
CEQ01_RS12195	COG4753	response regulator
CEQ01_RS12220	COG0383	alpha-mannosidase activity
CEQ01_RS12225	COG1940	carbohydrate kinase activity
CEQ01_RS12230	COG0564	pseudouridine synthase activity
CEQ01_RS12235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ01_RS12240	COG3679	Belongs to the UPF0342 family
CEQ01_RS12245	COG1132	(ABC) transporter
CEQ01_RS12255	COG2755	lipolytic protein G-D-S-L family
CEQ01_RS12260	COG1904	glucuronate isomerase
CEQ01_RS12265	COG2721	sulfolactate sulfo-lyase activity
CEQ01_RS12270	COG0246	Mannitol dehydrogenase
CEQ01_RS12275	COG1609	Transcriptional regulator
CEQ01_RS12280	COG2207	Transcriptional regulator
CEQ01_RS12290	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS12305	COG1653	transport
CEQ01_RS12310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEQ01_RS12320	COG1073	alpha beta
CEQ01_RS12335	COG3507	Belongs to the glycosyl hydrolase 43 family
CEQ01_RS12345	COG2211	Major facilitator Superfamily
CEQ01_RS12380	COG0561	phosphatase activity
CEQ01_RS12390	COG0420	3'-5' exonuclease activity
CEQ01_RS12395	COG4717	serine-type aminopeptidase activity
CEQ01_RS12400	COG3481	metal-dependent phosphohydrolase, HD sub domain
CEQ01_RS12405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ01_RS12415	COG0537	adenosine 5'-monophosphoramidase activity
CEQ01_RS12420	COG1131	(ABC) transporter
CEQ01_RS12425	COG4473	ABC transporter
CEQ01_RS12435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEQ01_RS12440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CEQ01_RS12445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ01_RS12450	COG1459	type II secretion system
CEQ01_RS12455	COG4537	Required for transformation and DNA binding
CEQ01_RS12480	COG0827	DNA restriction-modification system
CEQ01_RS12485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ01_RS12490	COG0488	(ABC) transporter
CEQ01_RS12500	COG0589	response to stress
CEQ01_RS12515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ01_RS12520	COG2094	Belongs to the DNA glycosylase MPG family
CEQ01_RS12530	COG2264	protein methyltransferase activity
CEQ01_RS12535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ01_RS12545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ01_RS12550	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ01_RS12555	COG2124	cytochrome p450
CEQ01_RS12560	COG0667	Aldo Keto reductase
CEQ01_RS12570	COG0124	histidyl-tRNA synthetase
CEQ01_RS12575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ01_RS12580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CEQ01_RS12585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEQ01_RS12585	COG2755	lipolytic protein G-D-S-L family
CEQ01_RS12590	COG2827	Endonuclease containing a URI domain
CEQ01_RS12595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEQ01_RS12600	COG0204	Acyl-transferase
CEQ01_RS12605	COG0420	3'-5' exonuclease activity
CEQ01_RS12610	COG0419	ATPase involved in DNA repair
CEQ01_RS12625	COG1393	Belongs to the ArsC family
CEQ01_RS12630	COG4862	establishment of competence for transformation
CEQ01_RS12650	COG4116	CYTH
CEQ01_RS12655	COG2357	RelA SpoT domain protein
CEQ01_RS12660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ01_RS12665	COG0564	pseudouridine synthase activity
CEQ01_RS12670	COG2239	Acts as a magnesium transporter
CEQ01_RS12675	COG3142	Participates in the control of copper homeostasis
CEQ01_RS12680	COG2226	methyltransferase
CEQ01_RS12685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEQ01_RS12695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ01_RS12705	COG2197	response regulator
CEQ01_RS12710	COG4585	Histidine kinase
CEQ01_RS12715	COG1131	(ABC) transporter
CEQ01_RS12730	COG1597	lipid kinase activity
CEQ01_RS12745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ01_RS12750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ01_RS12755	COG0250	Participates in transcription elongation, termination and antitermination
CEQ01_RS12760	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEQ01_RS12770	COG1760	l-serine dehydratase
CEQ01_RS12775	COG1760	l-serine dehydratase
CEQ01_RS12780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEQ01_RS12785	COG0081	regulation of translation
CEQ01_RS12790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ01_RS12795	COG0222	ribosome binding
CEQ01_RS12805	COG2814	Major facilitator Superfamily
CEQ01_RS12810	COG0488	(ABC) transporter
CEQ01_RS12815	COG0363	glucosamine-6-phosphate deaminase activity
CEQ01_RS12820	COG1285	pathogenesis
CEQ01_RS12825	COG0628	permease
CEQ01_RS12835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ01_RS12840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ01_RS12870	COG3448	diguanylate cyclase activity
CEQ01_RS12870	COG4175	Glycine betaine
CEQ01_RS12900	COG3279	Response regulator of the LytR AlgR family
CEQ01_RS12935	COG1714	RDD family
CEQ01_RS12955	COG1307	EDD domain protein, DegV family
CEQ01_RS12960	COG0745	RESPONSE REGULATOR receiver
CEQ01_RS12965	COG5002	protein histidine kinase activity
CEQ01_RS12980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEQ01_RS12985	COG2910	NAD(P)H-binding
CEQ01_RS12990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEQ01_RS13000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEQ01_RS13005	COG0459	protein refolding
CEQ01_RS13010	COG0582	viral genome integration into host DNA
CEQ01_RS13025	COG1396	sequence-specific DNA binding
CEQ01_RS13035	COG3561	AntA/AntB antirepressor
CEQ01_RS13240	COG0739	heme binding
CEQ01_RS13240	COG1196	nuclear chromosome segregation
CEQ01_RS13240	COG0741	lytic transglycosylase activity
CEQ01_RS13310	COG1609	Transcriptional regulator
CEQ01_RS13315	COG0789	Transcriptional regulator
CEQ01_RS13330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CEQ01_RS13335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEQ01_RS13355	COG1175	transmembrane transport
CEQ01_RS13360	COG0395	ABC-type sugar transport system, permease component
CEQ01_RS13370	COG3534	alpha-L-arabinofuranosidase
CEQ01_RS13375	COG3940	Belongs to the glycosyl hydrolase 43 family
CEQ01_RS13395	COG0235	Class ii aldolase
CEQ01_RS13400	COG2160	L-arabinose isomerase activity
CEQ01_RS13405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ01_RS13415	COG1368	sulfuric ester hydrolase activity
CEQ01_RS13425	COG2706	6-phosphogluconolactonase activity
CEQ01_RS13435	COG0628	permease
CEQ01_RS13440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEQ01_RS13460	COG1132	(ABC) transporter
CEQ01_RS13480	COG1482	cell wall glycoprotein biosynthetic process
CEQ01_RS13485	COG2213	PTS system mannitol-specific
CEQ01_RS13490	COG3711	transcriptional antiterminator
CEQ01_RS13495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS13505	COG1131	(ABC) transporter
CEQ01_RS13510	COG2213	PTS system mannitol-specific
CEQ01_RS13515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ01_RS13520	COG0246	Mannitol dehydrogenase
CEQ01_RS13525	COG3442	glutamine amidotransferase
CEQ01_RS13530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ01_RS13535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ01_RS13555	COG0681	Belongs to the peptidase S26 family
CEQ01_RS13560	COG2226	methyltransferase
CEQ01_RS13570	COG1435	thymidine kinase activity
CEQ01_RS13575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ01_RS13580	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ01_RS13590	COG0009	L-threonylcarbamoyladenylate synthase
CEQ01_RS13595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ01_RS13605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ01_RS13635	COG3328	transposase activity
CEQ01_RS13660	COG1126	abc transporter atp-binding protein
CEQ01_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ01_RS13675	COG2723	6-phospho-beta-galactosidase activity
CEQ01_RS13680	COG1280	lysine exporter protein (LysE YggA)
CEQ01_RS13680	COG1674	ftsk spoiiie
CEQ01_RS13685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEQ01_RS13715	COG4166	transmembrane transport
CEQ01_RS13725	COG0601	transmembrane transport
CEQ01_RS13730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ01_RS13735	COG0444	Belongs to the ABC transporter superfamily
CEQ01_RS13740	COG4608	Belongs to the ABC transporter superfamily
CEQ01_RS13745	COG0675	Transposase, IS605 OrfB family
CEQ01_RS13765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ01_RS13765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ01_RS13775	COG0531	amino acid
CEQ01_RS13780	COG0084	hydrolase, TatD family'
CEQ01_RS13785	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CEQ01_RS13790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ01_RS13800	COG3842	ATPase activity
CEQ01_RS13805	COG1803	Methylglyoxal synthase
CEQ01_RS13815	COG1132	(ABC) transporter
CEQ01_RS13820	COG1132	(ABC) transporter
CEQ01_RS13845	COG3715	PTS system
CEQ01_RS13850	COG3716	PTS system mannose fructose sorbose family IID component
CEQ01_RS13855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEQ01_RS13860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ01_RS13865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity