locus-tag	class	description
EWM55_RS00155	COG1674	ftsk spoiiie
EWM55_RS00155	COG0697	spore germination
EWM55_RS00190	COG3764	Sortase (surface protein transpeptidase)
EWM55_RS00315	COG3328	transposase activity
EWM55_RS00370	COG0542	response to heat
EWM55_RS00420	COG1598	PFAM Uncharacterised protein family UPF0150
EWM55_RS00585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EWM55_RS00590	COG0592	DNA-directed DNA polymerase activity
EWM55_RS00595	COG2501	S4 domain
EWM55_RS00600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EWM55_RS00605	COG0187	DNA topoisomerase II activity
EWM55_RS00615	COG0360	Binds together with S18 to 16S ribosomal RNA
EWM55_RS00620	COG0629	single-stranded DNA binding
EWM55_RS00625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EWM55_RS00635	COG0359	binds to the 23S rRNA
EWM55_RS00640	COG0305	Participates in initiation and elongation during chromosome replication
EWM55_RS00645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EWM55_RS00655	COG0488	(ABC) transporter
EWM55_RS00665	COG0028	Belongs to the TPP enzyme family
EWM55_RS00740	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS00750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS00750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS00805	COG1674	ftsk spoiiie
EWM55_RS00810	COG2946	Replication initiation factor
EWM55_RS00855	COG0741	lytic transglycosylase activity
EWM55_RS00855	COG0791	NLP P60 protein
EWM55_RS00935	COG0582	viral genome integration into host DNA
EWM55_RS00940	COG0519	Catalyzes the synthesis of GMP from XMP
EWM55_RS00940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EWM55_RS00945	COG1072	(Pantothenic acid kinase))
EWM55_RS00950	COG2813	Specifically methylates the guanine in position
EWM55_RS00955	COG1609	Transcriptional regulator
EWM55_RS00960	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EWM55_RS00965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EWM55_RS00970	COG0295	cytidine deaminase activity
EWM55_RS00975	COG1744	ABC transporter substrate-binding protein PnrA-like
EWM55_RS00980	COG3845	ABC transporter
EWM55_RS00985	COG4603	Belongs to the binding-protein-dependent transport system permease family
EWM55_RS00990	COG1079	Belongs to the binding-protein-dependent transport system permease family
EWM55_RS00995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EWM55_RS01005	COG0813	purine-nucleoside phosphorylase activity
EWM55_RS01015	COG0588	phosphoglycerate mutase activity
EWM55_RS01025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EWM55_RS01030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EWM55_RS01035	COG0049	tRNA binding
EWM55_RS01040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EWM55_RS01045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EWM55_RS01050	COG0051	transcription antitermination factor activity, RNA binding
EWM55_RS01055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EWM55_RS01060	COG0088	Forms part of the polypeptide exit tunnel
EWM55_RS01065	COG0089	rRNA binding
EWM55_RS01070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EWM55_RS01080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EWM55_RS01085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EWM55_RS01090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EWM55_RS01095	COG0255	Belongs to the universal ribosomal protein uL29 family
EWM55_RS01100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EWM55_RS01105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EWM55_RS01110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EWM55_RS01115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EWM55_RS01120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EWM55_RS01125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EWM55_RS01130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EWM55_RS01135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EWM55_RS01140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EWM55_RS01145	COG1841	ribosomal large subunit assembly
EWM55_RS01150	COG0200	Binds to the 23S rRNA
EWM55_RS01155	COG0201	protein transport
EWM55_RS01160	COG0563	adenylate kinase activity
EWM55_RS01165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EWM55_RS01170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EWM55_RS01175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EWM55_RS01180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EWM55_RS01185	COG0202	RNA polymerase activity
EWM55_RS01190	COG0203	ribosomal protein L17
EWM55_RS01195	COG1122	ATPase activity
EWM55_RS01200	COG1122	ATPase activity
EWM55_RS01210	COG0101	tRNA pseudouridine synthase activity
EWM55_RS01220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EWM55_RS01235	COG1461	Dihydroxyacetone kinase
EWM55_RS01240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EWM55_RS01245	COG0416	fatty acid biosynthetic process
EWM55_RS01250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EWM55_RS01260	COG4608	Belongs to the ABC transporter superfamily
EWM55_RS01265	COG0601	transmembrane transport
EWM55_RS01280	COG0571	ribonuclease III activity
EWM55_RS01285	COG1196	nuclear chromosome segregation
EWM55_RS01290	COG0561	phosphatase activity
EWM55_RS01295	COG0552	protein localization to endoplasmic reticulum
EWM55_RS01300	COG2918	glutathione biosynthetic process
EWM55_RS01300	COG1181	Belongs to the D-alanine--D-alanine ligase family
EWM55_RS01310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EWM55_RS01315	COG4605	iron ion homeostasis
EWM55_RS01320	COG4604	ABC transporter, ATP-binding protein
EWM55_RS01325	COG4607	ABC-type enterochelin transport system periplasmic component
EWM55_RS01345	COG2826	transposase and inactivated derivatives, IS30 family
EWM55_RS01355	COG4932	domain protein
EWM55_RS01355	COG4886	Leucine-rich repeat (LRR) protein
EWM55_RS01375	COG3328	transposase activity
EWM55_RS01395	COG1380	Effector of murein hydrolase LrgA
EWM55_RS01415	COG1028	Short-chain dehydrogenase reductase Sdr
EWM55_RS01425	COG1268	BioY protein
EWM55_RS01430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EWM55_RS01445	COG0561	phosphatase activity
EWM55_RS01455	COG1692	metallophosphoesterase
EWM55_RS01465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EWM55_RS01475	COG0424	maF-like protein
EWM55_RS01480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS01480	COG1263	PTS System
EWM55_RS01485	COG2188	Transcriptional regulator
EWM55_RS01495	COG0632	four-way junction helicase activity
EWM55_RS01500	COG2255	four-way junction helicase activity
EWM55_RS01510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EWM55_RS01520	COG3328	transposase activity
EWM55_RS01525	COG1114	Component of the transport system for branched-chain amino acids
EWM55_RS01535	COG1113	amino acid transport
EWM55_RS01540	COG1126	abc transporter atp-binding protein
EWM55_RS01545	COG0765	amino acid transport
EWM55_RS01560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EWM55_RS01565	COG0110	maltose O-acetyltransferase activity
EWM55_RS01570	COG1827	regulation of RNA biosynthetic process
EWM55_RS01580	COG0242	peptide deformylase activity
EWM55_RS01585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EWM55_RS01590	COG1185	polyribonucleotide nucleotidyltransferase activity
EWM55_RS01605	COG3158	transport of potassium into the cell
EWM55_RS01610	COG1253	flavin adenine dinucleotide binding
EWM55_RS01620	COG0534	Mate efflux family protein
EWM55_RS01630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EWM55_RS01635	COG1187	pseudouridine synthase activity
EWM55_RS01640	COG1011	Hydrolase
EWM55_RS01645	COG0572	uridine kinase
EWM55_RS01675	COG1671	Belongs to the UPF0178 family
EWM55_RS01685	COG1181	Belongs to the D-alanine--D-alanine ligase family
EWM55_RS01690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EWM55_RS01700	COG0736	holo-[acyl-carrier-protein] synthase activity
EWM55_RS01705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EWM55_RS01710	COG2337	Toxic component of a toxin-antitoxin (TA) module
EWM55_RS01720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EWM55_RS01725	COG3321	synthase
EWM55_RS01725	COG0604	alcohol dehydrogenase
EWM55_RS01740	COG0531	amino acid
EWM55_RS01770	COG1174	glycine betaine transport
EWM55_RS01805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EWM55_RS01825	COG0343	queuine tRNA-ribosyltransferase activity
EWM55_RS01830	COG1862	Preprotein translocase
EWM55_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
EWM55_RS01840	COG1454	alcohol dehydrogenase
EWM55_RS01845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EWM55_RS01875	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EWM55_RS01880	COG1028	Short-chain dehydrogenase reductase Sdr
EWM55_RS01885	COG1304	FMN binding
EWM55_RS01900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EWM55_RS01905	COG1428	Deoxynucleoside kinase
EWM55_RS01920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EWM55_RS01925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EWM55_RS01930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EWM55_RS01980	COG0824	Thioesterase
EWM55_RS01985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EWM55_RS02025	COG1363	Peptidase, m42
EWM55_RS02030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EWM55_RS02035	COG0589	response to stress
EWM55_RS02045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EWM55_RS02050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EWM55_RS02055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EWM55_RS02075	COG1674	ftsk spoiiie
EWM55_RS02085	COG2946	Replication initiation factor
EWM55_RS02120	COG0741	lytic transglycosylase activity
EWM55_RS02120	COG0791	NLP P60 protein
EWM55_RS02175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS02180	COG3414	Phosphotransferase system galactitol-specific IIB component
EWM55_RS02185	COG3775	system Galactitol-specific IIC component
EWM55_RS02210	COG1105	Belongs to the carbohydrate kinase PfkB family
EWM55_RS02215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS02215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS02215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS02220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS02220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS02220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS02225	COG3684	Belongs to the aldolase LacD family
EWM55_RS02240	COG2188	Transcriptional regulator
EWM55_RS02250	COG4807	Protein conserved in bacteria
EWM55_RS02260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EWM55_RS02280	COG2801	Transposase and inactivated derivatives
EWM55_RS02305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EWM55_RS02310	COG2190	(PTS) system
EWM55_RS02310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS02310	COG1263	PTS System
EWM55_RS02315	COG1263	PTS System
EWM55_RS02315	COG2190	(PTS) system
EWM55_RS02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS02325	COG3328	transposase activity
EWM55_RS02355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EWM55_RS02365	COG0101	tRNA pseudouridine synthase activity
EWM55_RS02380	COG2186	Transcriptional regulator
EWM55_RS02385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS02390	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS02400	COG1447	Phosphotransferase system cellobiose-specific component IIA
EWM55_RS02405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS02420	COG1063	alcohol dehydrogenase
EWM55_RS02430	COG4716	Myosin-crossreactive antigen
EWM55_RS02470	COG1113	amino acid transport
EWM55_RS02500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EWM55_RS02510	COG3052	prosthetic group binding
EWM55_RS02580	COG1051	belongs to the nudix hydrolase family
EWM55_RS02585	COG1846	Transcriptional regulator
EWM55_RS02610	COG2252	PERMEase
EWM55_RS02620	COG0366	Alpha amylase catalytic
EWM55_RS02625	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS02635	COG1263	PTS System
EWM55_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS02635	COG2190	(PTS) system
EWM55_RS02640	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS02655	COG1902	pentaerythritol trinitrate reductase activity
EWM55_RS02665	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS02675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EWM55_RS02680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EWM55_RS02685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EWM55_RS02695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EWM55_RS02715	COG1937	Protein conserved in bacteria
EWM55_RS02720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EWM55_RS02725	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS02730	COG3973	AAA domain
EWM55_RS02755	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EWM55_RS02760	COG2376	Dihydroxyacetone kinase
EWM55_RS02765	COG1461	Dihydroxyacetone kinase
EWM55_RS02780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EWM55_RS02790	COG1131	(ABC) transporter
EWM55_RS02795	COG1309	transcriptional regulator
EWM55_RS02815	COG0531	amino acid
EWM55_RS02820	COG1757	Na H antiporter
EWM55_RS02825	COG1609	Transcriptional regulator
EWM55_RS02835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS02845	COG1263	PTS System
EWM55_RS02845	COG2190	(PTS) system
EWM55_RS02845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS02875	COG3479	Phenolic acid decarboxylase
EWM55_RS02880	COG1695	Transcriptional regulator
EWM55_RS02890	COG2814	Major facilitator Superfamily
EWM55_RS02920	COG0163	prenyltransferase activity
EWM55_RS02925	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EWM55_RS02935	COG0577	efflux transmembrane transporter activity
EWM55_RS02935	COG1136	(ABC) transporter
EWM55_RS02955	COG1811	Na channel or pump
EWM55_RS02990	COG1136	(ABC) transporter
EWM55_RS03005	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS03005	COG3942	CHAP domain
EWM55_RS03010	COG1263	PTS System
EWM55_RS03010	COG2190	(PTS) system
EWM55_RS03010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS03015	COG1869	D-ribose catabolic process
EWM55_RS03025	COG1609	Transcriptional regulator
EWM55_RS03050	COG0366	Alpha amylase catalytic
EWM55_RS03060	COG0628	permease
EWM55_RS03065	COG3443	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS03065	COG0803	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS03090	COG1428	Deoxynucleoside kinase
EWM55_RS03105	COG0210	DNA helicase
EWM55_RS03125	COG1393	Belongs to the ArsC family
EWM55_RS03130	COG1393	Belongs to the ArsC family
EWM55_RS03160	COG0386	Belongs to the glutathione peroxidase family
EWM55_RS03165	COG1854	S-ribosylhomocysteine lyase activity
EWM55_RS03170	COG0626	cystathionine gamma-synthase activity
EWM55_RS03175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EWM55_RS03190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EWM55_RS03195	COG0019	diaminopimelate decarboxylase activity
EWM55_RS03200	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EWM55_RS03210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EWM55_RS03215	COG2171	N-acyltransferase activity
EWM55_RS03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EWM55_RS03225	COG0527	aspartate kinase activity
EWM55_RS03230	COG1473	amidohydrolase
EWM55_RS03235	COG0436	Aminotransferase
EWM55_RS03240	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS03260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EWM55_RS03265	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EWM55_RS03280	COG2207	Transcriptional regulator
EWM55_RS03285	COG2249	NAD(P)H dehydrogenase (quinone) activity
EWM55_RS03295	COG1113	amino acid transport
EWM55_RS03300	COG1121	(ABC) transporter
EWM55_RS03305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EWM55_RS03320	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EWM55_RS03325	COG2823	Periplasmic or secreted lipoprotein
EWM55_RS03325	COG1652	LysM domain
EWM55_RS03335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EWM55_RS03340	COG0477	Major facilitator Superfamily
EWM55_RS03350	COG1438	arginine binding
EWM55_RS03365	COG1764	response to oxidative stress
EWM55_RS03370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EWM55_RS03375	COG1335	isochorismatase
EWM55_RS03405	COG2135	peptidase activity
EWM55_RS03450	COG3546	catalase activity
EWM55_RS03460	COG1175	transmembrane transport
EWM55_RS03465	COG0395	ABC-type sugar transport system, permease component
EWM55_RS03505	COG0745	RESPONSE REGULATOR receiver
EWM55_RS03510	COG2205	protein histidine kinase activity
EWM55_RS03515	COG4975	Glucose uptake
EWM55_RS03520	COG0531	amino acid
EWM55_RS03525	COG3853	Toxic anion resistance protein (TelA)
EWM55_RS03550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EWM55_RS03555	COG1335	isochorismatase
EWM55_RS03570	COG3590	peptidase
EWM55_RS03580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EWM55_RS03585	COG1104	cysteine desulfurase activity
EWM55_RS03605	COG0482	sulfurtransferase activity
EWM55_RS03615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EWM55_RS03620	COG2814	Major facilitator Superfamily
EWM55_RS03640	COG0463	Glycosyl transferase, family 2
EWM55_RS03645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EWM55_RS03650	COG2855	membrane
EWM55_RS03665	COG0583	DNA-binding transcription factor activity
EWM55_RS03675	COG0772	Belongs to the SEDS family
EWM55_RS03680	COG1393	Belongs to the ArsC family
EWM55_RS03685	COG0509	glycine decarboxylation via glycine cleavage system
EWM55_RS03690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EWM55_RS03695	COG2011	ABC-type metal ion transport system permease component
EWM55_RS03700	COG1464	Belongs to the NlpA lipoprotein family
EWM55_RS03710	COG0719	Fe-S assembly protein
EWM55_RS03715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EWM55_RS03725	COG0719	Fe-S assembly protein
EWM55_RS03780	COG2190	(PTS) system
EWM55_RS03780	COG1263	PTS System
EWM55_RS03780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS03785	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS03790	COG3711	transcriptional antiterminator
EWM55_RS03820	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EWM55_RS03845	COG0577	efflux transmembrane transporter activity
EWM55_RS03845	COG1136	(ABC) transporter
EWM55_RS03855	COG3328	transposase activity
EWM55_RS03860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EWM55_RS03870	COG1597	lipid kinase activity
EWM55_RS03905	COG1733	regulation of RNA biosynthetic process
EWM55_RS03915	COG3764	Sortase (surface protein transpeptidase)
EWM55_RS03925	COG3711	transcriptional antiterminator
EWM55_RS03935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS03935	COG2190	(PTS) system
EWM55_RS03935	COG1263	PTS System
EWM55_RS03940	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS03945	COG2188	Transcriptional regulator
EWM55_RS03970	COG1611	Belongs to the LOG family
EWM55_RS03980	COG1428	Deoxynucleoside kinase
EWM55_RS03995	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS04015	COG1368	sulfuric ester hydrolase activity
EWM55_RS04025	COG0105	UTP biosynthetic process
EWM55_RS04030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EWM55_RS04035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS04045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EWM55_RS04050	COG2011	ABC-type metal ion transport system permease component
EWM55_RS04055	COG1464	Belongs to the NlpA lipoprotein family
EWM55_RS04065	COG1757	Na H antiporter
EWM55_RS04085	COG1113	amino acid transport
EWM55_RS04095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EWM55_RS04100	COG1929	Belongs to the glycerate kinase type-1 family
EWM55_RS04105	COG0488	(ABC) transporter
EWM55_RS04120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EWM55_RS04125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS04125	COG1263	PTS System
EWM55_RS04140	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EWM55_RS04145	COG1131	(ABC) transporter
EWM55_RS04165	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EWM55_RS04180	COG0346	lactoylglutathione lyase activity
EWM55_RS04205	COG0561	phosphatase activity
EWM55_RS04210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EWM55_RS04215	COG0280	phosphate acetyltransferase
EWM55_RS04220	COG0802	atpase or kinase
EWM55_RS04225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EWM55_RS04250	COG0708	Exodeoxyribonuclease III
EWM55_RS04260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EWM55_RS04285	COG1053	succinate dehydrogenase
EWM55_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
EWM55_RS04295	COG0604	alcohol dehydrogenase
EWM55_RS04295	COG3321	synthase
EWM55_RS04300	COG0702	epimerase
EWM55_RS04305	COG4684	Psort location CytoplasmicMembrane, score
EWM55_RS04310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EWM55_RS04315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EWM55_RS04320	COG0604	alcohol dehydrogenase
EWM55_RS04330	COG3842	ATPase activity
EWM55_RS04335	COG1176	ABC-type spermidine putrescine transport system, permease component I
EWM55_RS04340	COG1177	transmembrane transport
EWM55_RS04345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EWM55_RS04350	COG3829	transcription factor binding
EWM55_RS04365	COG3715	PTS system
EWM55_RS04370	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS04385	COG1940	carbohydrate kinase activity
EWM55_RS04425	COG0582	viral genome integration into host DNA
EWM55_RS04435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EWM55_RS04445	COG0789	Transcriptional regulator
EWM55_RS04465	COG0504	CTP synthase activity
EWM55_RS04480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EWM55_RS04485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EWM55_RS04490	COG0254	rRNA binding
EWM55_RS04515	COG1349	DNA-binding transcription factor activity
EWM55_RS04525	COG2814	Major facilitator Superfamily
EWM55_RS04535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EWM55_RS04555	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EWM55_RS04560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EWM55_RS04565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EWM55_RS04570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EWM55_RS04575	COG3870	Protein conserved in bacteria
EWM55_RS04580	COG0470	DNA polymerase III
EWM55_RS04585	COG1774	PSP1 C-terminal conserved region
EWM55_RS04590	COG4467	Involved in initiation control of chromosome replication
EWM55_RS04605	COG0602	queuosine metabolic process
EWM55_RS04610	COG1328	CTP reductase activity
EWM55_RS04615	COG1136	(ABC) transporter
EWM55_RS04620	COG0577	efflux transmembrane transporter activity
EWM55_RS04635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EWM55_RS04640	COG1696	Membrane protein involved in D-alanine export
EWM55_RS04645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EWM55_RS04650	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EWM55_RS04655	COG1363	Peptidase, m42
EWM55_RS04665	COG1234	tRNA 3'-trailer cleavage
EWM55_RS04670	COG0095	Lipoate-protein ligase
EWM55_RS04695	COG3759	membrane
EWM55_RS04700	COG0659	secondary active sulfate transmembrane transporter activity
EWM55_RS04710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EWM55_RS04720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EWM55_RS05005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EWM55_RS05005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EWM55_RS05010	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS05010	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS05020	COG3715	PTS system
EWM55_RS05025	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS05035	COG2261	transglycosylase associated protein
EWM55_RS05040	COG0006	proline dipeptidase activity
EWM55_RS05045	COG1302	Protein conserved in bacteria
EWM55_RS05050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EWM55_RS05055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EWM55_RS05060	COG1570	exodeoxyribonuclease VII activity
EWM55_RS05065	COG1722	exodeoxyribonuclease VII activity
EWM55_RS05075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EWM55_RS05080	COG1438	arginine binding
EWM55_RS05085	COG0497	DNA recombination
EWM55_RS05120	COG0768	penicillin binding
EWM55_RS05155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EWM55_RS05160	COG1799	cell septum assembly
EWM55_RS05170	COG2302	S4 RNA-binding domain
EWM55_RS05175	COG3599	regulation of cell shape
EWM55_RS05180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EWM55_RS05185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EWM55_RS05205	COG0673	inositol 2-dehydrogenase activity
EWM55_RS05210	COG0513	Belongs to the DEAD box helicase family
EWM55_RS05215	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EWM55_RS05215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EWM55_RS05220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS05225	COG1447	Phosphotransferase system cellobiose-specific component IIA
EWM55_RS05230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS05285	COG1396	sequence-specific DNA binding
EWM55_RS05450	COG0740	serine-type endopeptidase activity
EWM55_RS05550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EWM55_RS05555	COG0367	asparagine synthase
EWM55_RS05560	COG4876	unkown
EWM55_RS05565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EWM55_RS05580	COG1120	ATPase activity
EWM55_RS05585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EWM55_RS05590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EWM55_RS05595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EWM55_RS05610	COG1940	carbohydrate kinase activity
EWM55_RS05615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EWM55_RS05620	COG3189	MarR family transcriptional regulator
EWM55_RS05635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EWM55_RS05640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EWM55_RS05645	COG1609	Transcriptional regulator
EWM55_RS05650	COG1214	PFAM Peptidase M22, glycoprotease
EWM55_RS05660	COG0456	acetyltransferase
EWM55_RS05665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EWM55_RS05670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EWM55_RS05675	COG2235	arginine
EWM55_RS05690	COG0018	arginyl-trna synthetase
EWM55_RS05700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS05710	COG1438	arginine binding
EWM55_RS05715	COG0052	Belongs to the universal ribosomal protein uS2 family
EWM55_RS05720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EWM55_RS05725	COG0528	UMP kinase activity
EWM55_RS05730	COG0233	cytoplasmic translational termination
EWM55_RS05740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EWM55_RS05745	COG4589	Belongs to the CDS family
EWM55_RS05750	COG0750	zinc metalloprotease
EWM55_RS05755	COG0442	prolyl-tRNA aminoacylation
EWM55_RS05760	COG2176	DNA-directed DNA polymerase activity
EWM55_RS05765	COG0779	Required for maturation of 30S ribosomal subunits
EWM55_RS05770	COG0195	Participates in both transcription termination and antitermination
EWM55_RS05775	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EWM55_RS05790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EWM55_RS05795	COG1175	transmembrane transport
EWM55_RS05800	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EWM55_RS05810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EWM55_RS05815	COG0196	riboflavin kinase activity
EWM55_RS05825	COG4975	Glucose uptake
EWM55_RS05835	COG5646	InterPro IPR014922
EWM55_RS05845	COG1619	proteins homologs of microcin C7 resistance protein MccF
EWM55_RS05865	COG0693	protein deglycase activity
EWM55_RS05895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EWM55_RS05900	COG1420	regulation of RNA biosynthetic process
EWM55_RS05905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EWM55_RS05910	COG0443	Heat shock 70 kDa protein
EWM55_RS05915	COG0484	heat shock protein binding
EWM55_RS05925	COG1126	abc transporter atp-binding protein
EWM55_RS05930	COG0765	amino acid transport
EWM55_RS05935	COG0556	nucleotide-excision repair
EWM55_RS05940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EWM55_RS05955	COG1660	Displays ATPase and GTPase activities
EWM55_RS05960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EWM55_RS05965	COG1481	regulation of sporulation
EWM55_RS06020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EWM55_RS06025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EWM55_RS06045	COG1714	RDD family
EWM55_RS06055	COG0544	peptidyl-prolyl cis-trans isomerase activity
EWM55_RS06060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EWM55_RS06065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EWM55_RS06080	COG1349	DNA-binding transcription factor activity
EWM55_RS06085	COG1105	Belongs to the carbohydrate kinase PfkB family
EWM55_RS06090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS06090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS06090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS06100	COG0210	DNA helicase
EWM55_RS06105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EWM55_RS06110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EWM55_RS06115	COG0154	amidase activity
EWM55_RS06120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EWM55_RS06125	COG1597	lipid kinase activity
EWM55_RS06130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EWM55_RS06145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EWM55_RS06155	COG1609	Transcriptional regulator
EWM55_RS06170	COG3250	beta-galactosidase activity
EWM55_RS06180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EWM55_RS06190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EWM55_RS06195	COG0287	Prephenate dehydrogenase
EWM55_RS06200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EWM55_RS06205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EWM55_RS06210	COG0077	Prephenate dehydratase
EWM55_RS06215	COG2972	Histidine kinase
EWM55_RS06225	COG2207	Transcriptional regulator
EWM55_RS06225	COG4753	response regulator
EWM55_RS06280	COG0588	phosphoglycerate mutase activity
EWM55_RS06285	COG0546	phosphoglycolate phosphatase activity
EWM55_RS06315	COG1054	Belongs to the UPF0176 family
EWM55_RS06325	COG2183	response to ionizing radiation
EWM55_RS06330	COG3091	SprT-like family
EWM55_RS06335	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EWM55_RS06340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EWM55_RS06355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EWM55_RS06355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EWM55_RS06360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EWM55_RS06365	COG0237	dephospho-CoA kinase activity
EWM55_RS06375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EWM55_RS06385	COG1484	DNA-dependent DNA replication
EWM55_RS06405	COG2384	SAM-dependent methyltransferase
EWM55_RS06410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EWM55_RS06415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EWM55_RS06420	COG1597	lipid kinase activity
EWM55_RS06435	COG0542	response to heat
EWM55_RS06455	COG0481	GTPase activity
EWM55_RS06460	COG4974	Belongs to the 'phage' integrase family
EWM55_RS06470	COG3328	transposase activity
EWM55_RS06510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS06510	COG3711	transcriptional antiterminator
EWM55_RS06520	COG3730	PTS system glucitol sorbitol-specific
EWM55_RS06525	COG3732	PTS system glucitol sorbitol-specific
EWM55_RS06545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EWM55_RS06585	COG2272	Belongs to the type-B carboxylesterase lipase family
EWM55_RS06595	COG1737	Transcriptional regulator
EWM55_RS06595	COG0837	glucose binding
EWM55_RS06600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EWM55_RS06615	COG0371	Dehydrogenase
EWM55_RS06625	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS06630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS06650	COG1312	Catalyzes the dehydration of D-mannonate
EWM55_RS06655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS06660	COG1278	Cold shock
EWM55_RS06680	COG1476	TRANSCRIPTIONal
EWM55_RS06705	COG0561	phosphatase activity
EWM55_RS06710	COG1442	glycosyl transferase family 8
EWM55_RS06715	COG1442	glycosyl transferase family 8
EWM55_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
EWM55_RS06750	COG2261	transglycosylase associated protein
EWM55_RS06760	COG3655	Transcriptional regulator
EWM55_RS06795	COG2261	transglycosylase associated protein
EWM55_RS06805	COG0004	ammonium transporteR
EWM55_RS06810	COG0531	amino acid
EWM55_RS06825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EWM55_RS06840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EWM55_RS06950	COG0450	alkyl hydroperoxide reductase
EWM55_RS06960	COG0246	Mannitol dehydrogenase
EWM55_RS06965	COG1312	Catalyzes the dehydration of D-mannonate
EWM55_RS06980	COG0628	permease
EWM55_RS06985	COG1846	Transcriptional regulator
EWM55_RS06990	COG1764	response to oxidative stress
EWM55_RS07000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EWM55_RS07005	COG0366	Alpha amylase catalytic
EWM55_RS07010	COG2182	Extracellular solute-binding protein
EWM55_RS07015	COG1175	transmembrane transport
EWM55_RS07020	COG3833	ABC-type maltose transport systems, permease component
EWM55_RS07030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EWM55_RS07040	COG0167	dihydroorotate dehydrogenase activity
EWM55_RS07050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EWM55_RS07055	COG0765	amino acid transport
EWM55_RS07075	COG0194	GDP metabolic process
EWM55_RS07080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EWM55_RS07135	COG2244	polysaccharide biosynthetic process
EWM55_RS07140	COG1307	EDD domain protein, DegV family
EWM55_RS07160	COG0366	Alpha amylase catalytic
EWM55_RS07165	COG4475	Protein of unknown function (DUF436)
EWM55_RS07175	COG0351	phosphomethylpyrimidine kinase
EWM55_RS07180	COG0318	PFAM AMP-dependent synthetase and ligase
EWM55_RS07190	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
EWM55_RS07195	COG5002	protein histidine kinase activity
EWM55_RS07200	COG0745	RESPONSE REGULATOR receiver
EWM55_RS07250	COG0673	inositol 2-dehydrogenase activity
EWM55_RS07260	COG3711	transcriptional antiterminator
EWM55_RS07270	COG3037	sugar-specific permease SgaT UlaA
EWM55_RS07290	COG0039	L-malate dehydrogenase activity
EWM55_RS07330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EWM55_RS07340	COG4120	Belongs to the binding-protein-dependent transport system permease family
EWM55_RS07360	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EWM55_RS07400	COG0284	orotidine-5'-phosphate decarboxylase activity
EWM55_RS07410	COG0543	2 iron, 2 sulfur cluster binding
EWM55_RS07415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EWM55_RS07420	COG0505	Belongs to the CarA family
EWM55_RS07425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EWM55_RS07430	COG0540	Belongs to the ATCase OTCase family
EWM55_RS07435	COG2233	PERMEase
EWM55_RS07445	COG0564	pseudouridine synthase activity
EWM55_RS07450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EWM55_RS07465	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EWM55_RS07470	COG1278	Cold shock
EWM55_RS07480	COG0328	RNA-DNA hybrid ribonuclease activity
EWM55_RS07490	COG4684	Psort location CytoplasmicMembrane, score
EWM55_RS07495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EWM55_RS07505	COG2153	protein acetylation
EWM55_RS07510	COG0513	Belongs to the DEAD box helicase family
EWM55_RS07525	COG0531	amino acid
EWM55_RS07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EWM55_RS07535	COG0156	8-amino-7-oxononanoate synthase activity
EWM55_RS07550	COG1418	mRNA catabolic process
EWM55_RS07555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EWM55_RS07560	COG0116	Belongs to the methyltransferase superfamily
EWM55_RS07570	COG3599	regulation of cell shape
EWM55_RS07575	COG4474	Belongs to the UPF0398 family
EWM55_RS07580	COG3331	DNA recombination
EWM55_RS07585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EWM55_RS07595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EWM55_RS07600	COG3935	DnaD domain protein
EWM55_RS07610	COG1846	Transcriptional regulator
EWM55_RS07625	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS07630	COG0735	belongs to the Fur family
EWM55_RS07635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EWM55_RS07640	COG1388	LysM domain
EWM55_RS07640	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS07645	COG2826	transposase and inactivated derivatives, IS30 family
EWM55_RS07660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EWM55_RS07670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EWM55_RS07675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EWM55_RS07675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EWM55_RS07680	COG5416	Lipopolysaccharide assembly protein A domain
EWM55_RS07685	COG0300	oxidoreductase activity
EWM55_RS07690	COG1234	tRNA 3'-trailer cleavage
EWM55_RS07700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EWM55_RS07730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EWM55_RS07735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EWM55_RS07740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EWM55_RS07745	COG0668	transmembrane transport
EWM55_RS07750	COG0517	IMP dehydrogenase activity
EWM55_RS07760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EWM55_RS07765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EWM55_RS07775	COG0765	amino acid transport
EWM55_RS07780	COG0765	amino acid transport
EWM55_RS07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EWM55_RS07790	COG1126	abc transporter atp-binding protein
EWM55_RS07800	COG0072	phenylalanine-tRNA ligase activity
EWM55_RS07800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EWM55_RS07805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EWM55_RS07810	COG1733	regulation of RNA biosynthetic process
EWM55_RS07815	COG1074	ATP-dependent DNA helicase activity
EWM55_RS07820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EWM55_RS07830	COG3104	oligopeptide transport
EWM55_RS07850	COG4990	cell redox homeostasis
EWM55_RS07905	COG3942	CHAP domain
EWM55_RS07905	COG1388	LysM domain
EWM55_RS07920	COG2151	metal-sulfur cluster biosynthetic enzyme
EWM55_RS07925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EWM55_RS07930	COG1666	GTP binding
EWM55_RS07950	COG1968	undecaprenyl-diphosphatase activity
EWM55_RS07955	COG2217	Heavy metal translocating P-type atpase
EWM55_RS07960	COG2707	UPF0756 membrane protein
EWM55_RS07970	COG0268	Binds directly to 16S ribosomal RNA
EWM55_RS07975	COG1466	dna polymerase III delta subunit
EWM55_RS07980	COG2333	competence protein COMEC
EWM55_RS07980	COG0658	competence protein
EWM55_RS07985	COG2131	deaminase
EWM55_RS08000	COG1596	polysaccharide export
EWM55_RS08000	COG1555	photosystem II stabilization
EWM55_RS08015	COG3480	Lon protease (S16) C-terminal proteolytic domain
EWM55_RS08020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EWM55_RS08025	COG0742	ribosomal rna small subunit methyltransferase
EWM55_RS08030	COG4471	UPF0298 protein
EWM55_RS08045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EWM55_RS08050	COG0772	Belongs to the SEDS family
EWM55_RS08055	COG4838	Belongs to the UPF0358 family
EWM55_RS08060	COG0514	ATP-dependent DNA helicase (RecQ)
EWM55_RS08065	COG1217	gtp-binding protein TYPA
EWM55_RS08070	COG0483	inositol monophosphate 1-phosphatase activity
EWM55_RS08075	COG4476	Belongs to the UPF0223 family
EWM55_RS08090	COG0022	dehydrogenase e1 component
EWM55_RS08105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EWM55_RS08115	COG0516	GMP reductase activity
EWM55_RS08120	COG4214	carbohydrate transport
EWM55_RS08130	COG4213	ABC transporter substrate-binding protein
EWM55_RS08140	COG2972	Histidine kinase
EWM55_RS08150	COG4989	oxidoreductase activity
EWM55_RS08155	COG0151	Belongs to the GarS family
EWM55_RS08160	COG0138	bifunctional purine biosynthesis protein purh
EWM55_RS08165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EWM55_RS08170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EWM55_RS08180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EWM55_RS08185	COG0047	phosphoribosylformylglycinamidine synthase activity
EWM55_RS08190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EWM55_RS08195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EWM55_RS08215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EWM55_RS08220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EWM55_RS08225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EWM55_RS08235	COG2233	PERMEase
EWM55_RS08240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EWM55_RS08245	COG0673	inositol 2-dehydrogenase activity
EWM55_RS08255	COG0395	ABC-type sugar transport system, permease component
EWM55_RS08260	COG1175	transmembrane transport
EWM55_RS08265	COG1653	transport
EWM55_RS08275	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS08275	COG1388	LysM domain
EWM55_RS08280	COG1876	peptidase activity
EWM55_RS08290	COG0673	inositol 2-dehydrogenase activity
EWM55_RS08310	COG2268	Band 7 protein
EWM55_RS08320	COG3290	protein histidine kinase activity
EWM55_RS08325	COG3290	protein histidine kinase activity
EWM55_RS08330	COG4565	transcriptional regulatory protein
EWM55_RS08335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EWM55_RS08360	COG0436	Aminotransferase
EWM55_RS08375	COG3328	transposase activity
EWM55_RS08385	COG0346	lactoylglutathione lyase activity
EWM55_RS08415	COG3942	CHAP domain
EWM55_RS08415	COG1388	LysM domain
EWM55_RS08420	COG0084	hydrolase, TatD family'
EWM55_RS08425	COG1116	anion transmembrane transporter activity
EWM55_RS08435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EWM55_RS08450	COG1732	Glycine betaine
EWM55_RS08470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EWM55_RS08480	COG1609	Transcriptional regulator
EWM55_RS08485	COG1073	alpha beta
EWM55_RS08495	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EWM55_RS08515	COG1227	inorganic diphosphatase activity
EWM55_RS08520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EWM55_RS08525	COG1882	Formate acetyltransferase
EWM55_RS08535	COG0187	DNA topoisomerase II activity
EWM55_RS08540	COG1832	CoA-binding protein
EWM55_RS08545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EWM55_RS08560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EWM55_RS08565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EWM55_RS08575	COG4974	Belongs to the 'phage' integrase family
EWM55_RS08580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EWM55_RS08585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EWM55_RS08590	COG0758	DNA mediated transformation
EWM55_RS08595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EWM55_RS08600	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EWM55_RS08615	COG0681	Belongs to the peptidase S26 family
EWM55_RS08620	COG4479	Belongs to the UPF0346 family
EWM55_RS08630	COG4698	Protein conserved in bacteria
EWM55_RS08635	COG2755	lipolytic protein G-D-S-L family
EWM55_RS08640	COG1307	EDD domain protein, DegV family
EWM55_RS08645	COG1272	protein, Hemolysin III
EWM55_RS08655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EWM55_RS08660	COG0488	(ABC) transporter
EWM55_RS08665	COG0025	NhaP-type Na H and K H
EWM55_RS08680	COG0617	tRNA 3'-terminal CCA addition
EWM55_RS08685	COG1694	Mazg nucleotide pyrophosphohydrolase
EWM55_RS08690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EWM55_RS08695	COG5582	Belongs to the UPF0302 family
EWM55_RS08700	COG0457	Tetratricopeptide repeat
EWM55_RS08720	COG0776	regulation of translation
EWM55_RS08725	COG1160	GTP binding
EWM55_RS08730	COG0539	negative regulation of cytoplasmic translation
EWM55_RS08735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EWM55_RS08745	COG0514	ATP-dependent DNA helicase (RecQ)
EWM55_RS08765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EWM55_RS08770	COG1288	antiporter activity
EWM55_RS08775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EWM55_RS08780	COG1187	pseudouridine synthase activity
EWM55_RS08785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EWM55_RS08790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EWM55_RS08800	COG4974	Belongs to the 'phage' integrase family
EWM55_RS08805	COG0735	belongs to the Fur family
EWM55_RS08810	COG2996	Protein conserved in bacteria
EWM55_RS08820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EWM55_RS08825	COG0358	DNA primase activity
EWM55_RS08830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EWM55_RS08845	COG0596	Alpha beta hydrolase
EWM55_RS08850	COG0392	lysyltransferase activity
EWM55_RS08850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EWM55_RS08870	COG0656	L-ascorbic acid biosynthetic process
EWM55_RS08885	COG0183	Belongs to the thiolase family
EWM55_RS08890	COG3425	synthase
EWM55_RS08900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EWM55_RS08905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EWM55_RS08910	COG0351	phosphomethylpyrimidine kinase
EWM55_RS08920	COG1393	Belongs to the ArsC family
EWM55_RS08935	COG0589	response to stress
EWM55_RS08940	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS08945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS08950	COG2188	Transcriptional regulator
EWM55_RS08960	COG0346	lactoylglutathione lyase activity
EWM55_RS08965	COG0400	carboxylic ester hydrolase activity
EWM55_RS08980	COG3775	system Galactitol-specific IIC component
EWM55_RS08995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS09000	COG1349	DNA-binding transcription factor activity
EWM55_RS09005	COG1105	Belongs to the carbohydrate kinase PfkB family
EWM55_RS09020	COG0789	Transcriptional regulator
EWM55_RS09025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EWM55_RS09030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EWM55_RS09035	COG3711	transcriptional antiterminator
EWM55_RS09035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS09040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS09040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS09040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EWM55_RS09055	COG3964	amidohydrolase
EWM55_RS09090	COG3711	transcriptional antiterminator
EWM55_RS09115	COG0456	acetyltransferase
EWM55_RS09125	COG3623	hexulose-6-phosphate isomerase
EWM55_RS09130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EWM55_RS09155	COG1349	DNA-binding transcription factor activity
EWM55_RS09180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS09185	COG1263	PTS System
EWM55_RS09185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS09185	COG2190	(PTS) system
EWM55_RS09190	COG1486	melibiose metabolic process
EWM55_RS09195	COG1263	PTS System
EWM55_RS09195	COG2190	(PTS) system
EWM55_RS09195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS09205	COG3711	transcriptional antiterminator
EWM55_RS09310	COG5002	protein histidine kinase activity
EWM55_RS09315	COG0745	RESPONSE REGULATOR receiver
EWM55_RS09320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EWM55_RS09325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EWM55_RS09335	COG0583	DNA-binding transcription factor activity
EWM55_RS09345	COG0205	6-phosphofructokinase activity
EWM55_RS09350	COG0587	DNA-directed DNA polymerase activity
EWM55_RS09360	COG2814	Major facilitator Superfamily
EWM55_RS09365	COG2252	PERMEase
EWM55_RS09370	COG0561	phosphatase activity
EWM55_RS09380	COG0768	penicillin binding
EWM55_RS09385	COG1737	Transcriptional regulator
EWM55_RS09390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EWM55_RS09400	COG1942	4-Oxalocrotonate Tautomerase
EWM55_RS09405	COG2217	Heavy metal translocating P-type atpase
EWM55_RS09410	COG3973	AAA domain
EWM55_RS09420	COG0217	transcriptional regulatory protein
EWM55_RS09425	COG1323	Belongs to the UPF0348 family
EWM55_RS09430	COG2226	methyltransferase
EWM55_RS09435	COG0799	negative regulation of ribosome biogenesis
EWM55_RS09440	COG1713	HD superfamily hydrolase involved in NAD metabolism
EWM55_RS09445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EWM55_RS09450	COG1534	Rna-binding protein
EWM55_RS09455	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EWM55_RS09460	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EWM55_RS09465	COG0825	malonyl-CoA metabolic process
EWM55_RS09470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EWM55_RS09475	COG0439	Biotin carboxylase
EWM55_RS09480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EWM55_RS09490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EWM55_RS09500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EWM55_RS09510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EWM55_RS09515	COG1846	Transcriptional regulator
EWM55_RS09520	COG0322	excinuclease ABC activity
EWM55_RS09525	COG4703	Protein of unknown function (DUF1797)
EWM55_RS09530	COG2084	Dehydrogenase
EWM55_RS09535	COG0438	transferase activity, transferring glycosyl groups
EWM55_RS09545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EWM55_RS09550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS09555	COG0542	response to heat
EWM55_RS09575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EWM55_RS09585	COG1253	flavin adenine dinucleotide binding
EWM55_RS09590	COG0628	permease
EWM55_RS09600	COG3557	Belongs to the UPF0374 family
EWM55_RS09605	COG1194	a g-specific adenine glycosylase
EWM55_RS09610	COG2137	regulation of response to DNA damage stimulus
EWM55_RS09615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EWM55_RS09620	COG3397	chitin binding
EWM55_RS09625	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EWM55_RS09630	COG1316	TRANSCRIPTIONal
EWM55_RS09640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EWM55_RS09645	COG2246	polysaccharide biosynthetic process
EWM55_RS09675	COG0569	domain protein
EWM55_RS09685	COG4585	Histidine kinase
EWM55_RS09695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EWM55_RS09700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EWM55_RS09720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EWM55_RS09735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EWM55_RS09735	COG0463	Glycosyl transferase, family 2
EWM55_RS09740	COG1216	Glycosyl transferase, family 2
EWM55_RS09740	COG1442	glycosyl transferase family 8
EWM55_RS09745	COG1215	transferase activity, transferring glycosyl groups
EWM55_RS09750	COG1216	Glycosyl transferase, family 2
EWM55_RS09755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EWM55_RS09760	COG0438	transferase activity, transferring glycosyl groups
EWM55_RS09760	COG1216	Glycosyl transferase, family 2
EWM55_RS09765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EWM55_RS09775	COG1682	transport, permease protein
EWM55_RS09805	COG1091	dTDP-4-dehydrorhamnose reductase activity
EWM55_RS09810	COG1088	dTDP-glucose 4,6-dehydratase activity
EWM55_RS09820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EWM55_RS09825	COG1215	transferase activity, transferring glycosyl groups
EWM55_RS09840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EWM55_RS09845	COG1295	ribonuclease BN
EWM55_RS09850	COG0024	Methionine aminopeptidase
EWM55_RS09855	COG0716	FMN binding
EWM55_RS09865	COG2309	aminopeptidase activity
EWM55_RS10035	COG2801	Transposase and inactivated derivatives
EWM55_RS10140	COG1396	sequence-specific DNA binding
EWM55_RS10170	COG1309	transcriptional regulator
EWM55_RS10190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EWM55_RS10210	COG0584	glycerophosphoryl diester phosphodiesterase
EWM55_RS10225	COG0166	Belongs to the GPI family
EWM55_RS10230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EWM55_RS10235	COG2081	HI0933 family
EWM55_RS10240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EWM55_RS10245	COG0710	3-dehydroquinate dehydratase activity
EWM55_RS10250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EWM55_RS10255	COG1368	sulfuric ester hydrolase activity
EWM55_RS10290	COG3850	Histidine kinase
EWM55_RS10290	COG5002	protein histidine kinase activity
EWM55_RS10295	COG0745	RESPONSE REGULATOR receiver
EWM55_RS10320	COG2826	transposase and inactivated derivatives, IS30 family
EWM55_RS10340	COG1956	GAF domain-containing protein
EWM55_RS10345	COG3527	Alpha-acetolactate decarboxylase
EWM55_RS10350	COG0028	Belongs to the TPP enzyme family
EWM55_RS10360	COG0395	ABC-type sugar transport system, permease component
EWM55_RS10365	COG1175	transmembrane transport
EWM55_RS10420	COG0335	large ribosomal subunit rRNA binding
EWM55_RS10425	COG0336	Belongs to the RNA methyltransferase TrmD family
EWM55_RS10430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EWM55_RS10440	COG1837	Belongs to the UPF0109 family
EWM55_RS10445	COG0228	four-way junction DNA binding
EWM55_RS10450	COG0431	NADPH-dependent FMN reductase
EWM55_RS10455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EWM55_RS10460	COG0519	Catalyzes the synthesis of GMP from XMP
EWM55_RS10465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EWM55_RS10470	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EWM55_RS10480	COG0745	RESPONSE REGULATOR receiver
EWM55_RS10485	COG5002	protein histidine kinase activity
EWM55_RS10490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EWM55_RS10495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EWM55_RS10520	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EWM55_RS10565	COG0714	Associated with various cellular activities
EWM55_RS10580	COG2217	Heavy metal translocating P-type atpase
EWM55_RS10585	COG2217	Heavy metal translocating P-type atpase
EWM55_RS10590	COG2608	mercury ion transmembrane transporter activity
EWM55_RS10595	COG3682	Transcriptional regulator
EWM55_RS10605	COG0531	amino acid
EWM55_RS10610	COG2217	Heavy metal translocating P-type atpase
EWM55_RS10635	COG0017	Asparaginyl-tRNA synthetase
EWM55_RS10640	COG0436	Aminotransferase
EWM55_RS10650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EWM55_RS10650	COG1199	ATP-dependent helicase activity
EWM55_RS10655	COG1278	Cold shock
EWM55_RS10680	COG1686	Belongs to the peptidase S11 family
EWM55_RS10690	COG0038	chloride channel
EWM55_RS10710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EWM55_RS10715	COG1254	Belongs to the acylphosphatase family
EWM55_RS10730	COG0706	membrane insertase activity
EWM55_RS10785	COG2207	Transcriptional regulator
EWM55_RS10790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EWM55_RS10795	COG1482	cell wall glycoprotein biosynthetic process
EWM55_RS10800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EWM55_RS10800	COG0662	Cupin 2, conserved barrel domain protein
EWM55_RS10805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EWM55_RS10815	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EWM55_RS10895	COG0438	transferase activity, transferring glycosyl groups
EWM55_RS10925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EWM55_RS10955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EWM55_RS10960	COG4464	protein tyrosine phosphatase activity
EWM55_RS10965	COG0489	protein tyrosine kinase activity
EWM55_RS10970	COG3944	biosynthesis protein
EWM55_RS10975	COG1316	TRANSCRIPTIONal
EWM55_RS10985	COG0751	glycine-tRNA ligase activity
EWM55_RS10990	COG0752	glycyl-tRNA synthetase alpha subunit
EWM55_RS10995	COG1381	Involved in DNA repair and RecF pathway recombination
EWM55_RS11000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EWM55_RS11005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EWM55_RS11010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EWM55_RS11020	COG1702	phosphate starvation-inducible protein PhoH
EWM55_RS11025	COG1114	Component of the transport system for branched-chain amino acids
EWM55_RS11030	COG1610	YqeY-like protein
EWM55_RS11035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EWM55_RS11040	COG0735	belongs to the Fur family
EWM55_RS11045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EWM55_RS11050	COG0640	Transcriptional regulator
EWM55_RS11055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EWM55_RS11060	COG0492	ferredoxin-NADP+ reductase activity
EWM55_RS11065	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS11070	COG1486	melibiose metabolic process
EWM55_RS11080	COG1737	Transcriptional regulator
EWM55_RS11085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS11085	COG2190	(PTS) system
EWM55_RS11085	COG1263	PTS System
EWM55_RS11090	COG3711	transcriptional antiterminator
EWM55_RS11095	COG1132	(ABC) transporter
EWM55_RS11100	COG1132	(ABC) transporter
EWM55_RS11105	COG3763	UPF0154 protein
EWM55_RS11115	COG1914	H( )-stimulated, divalent metal cation uptake system
EWM55_RS11130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EWM55_RS11160	COG1609	Transcriptional regulator
EWM55_RS11170	COG4980	gas vesicle protein
EWM55_RS11180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EWM55_RS11185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EWM55_RS11190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EWM55_RS11195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EWM55_RS11200	COG1950	PFAM Membrane protein of
EWM55_RS11230	COG0704	Plays a role in the regulation of phosphate uptake
EWM55_RS11235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EWM55_RS11240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EWM55_RS11245	COG0581	inorganic phosphate transmembrane transporter activity
EWM55_RS11250	COG0573	inorganic phosphate transmembrane transporter activity
EWM55_RS11255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EWM55_RS11260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EWM55_RS11265	COG2177	Part of the ABC transporter FtsEX involved in
EWM55_RS11270	COG2884	Cell division ATP-binding protein ftsE
EWM55_RS11280	COG0653	protein targeting
EWM55_RS11295	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EWM55_RS11300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS11310	COG1739	Uncharacterized protein family UPF0029
EWM55_RS11315	COG2188	Transcriptional regulator
EWM55_RS11335	COG1940	carbohydrate kinase activity
EWM55_RS11355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EWM55_RS11385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EWM55_RS11390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EWM55_RS11395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EWM55_RS11400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EWM55_RS11405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EWM55_RS11410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EWM55_RS11415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EWM55_RS11420	COG0356	it plays a direct role in the translocation of protons across the membrane
EWM55_RS11425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EWM55_RS11430	COG0557	exoribonuclease II activity
EWM55_RS11440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EWM55_RS11445	COG2388	GCN5-related N-acetyl-transferase
EWM55_RS11455	COG1957	nucleoside hydrolase
EWM55_RS11480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EWM55_RS11495	COG0149	triose-phosphate isomerase activity
EWM55_RS11500	COG0126	phosphoglycerate kinase activity
EWM55_RS11510	COG2390	Transcriptional regulator
EWM55_RS11515	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EWM55_RS11535	COG1595	DNA-templated transcription, initiation
EWM55_RS11555	COG0095	Lipoate-protein ligase
EWM55_RS11560	COG1078	dGTPase activity
EWM55_RS11565	COG0561	phosphatase activity
EWM55_RS11570	COG0494	nUDIX hydrolase
EWM55_RS11575	COG0346	lactoylglutathione lyase activity
EWM55_RS11585	COG2423	ornithine cyclodeaminase activity
EWM55_RS11590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EWM55_RS11595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EWM55_RS11600	COG1394	ATPase activity, coupled to movement of substances
EWM55_RS11605	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
EWM55_RS11610	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EWM55_RS11615	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EWM55_RS11620	COG1527	subunit (C
EWM55_RS11625	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
EWM55_RS11630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EWM55_RS11635	COG1269	ATP hydrolysis coupled proton transport
EWM55_RS11645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EWM55_RS11650	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EWM55_RS11660	COG4152	abc transporter atp-binding protein
EWM55_RS11665	COG0322	excinuclease ABC activity
EWM55_RS11670	COG3118	belongs to the thioredoxin family
EWM55_RS11675	COG1193	negative regulation of DNA recombination
EWM55_RS11690	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EWM55_RS11705	COG1136	(ABC) transporter
EWM55_RS11715	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS11750	COG1304	FMN binding
EWM55_RS11765	COG0281	malic enzyme
EWM55_RS11810	COG4695	Portal protein
EWM55_RS11890	COG4974	Belongs to the 'phage' integrase family
EWM55_RS11975	COG0582	viral genome integration into host DNA
EWM55_RS11980	COG3906	Belongs to the UPF0473 family
EWM55_RS11985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EWM55_RS11990	COG4472	Bacterial protein of unknown function (DUF965)
EWM55_RS12020	COG4555	ABC transporter
EWM55_RS12030	COG3689	TIGRFAM TIGR03943 family protein
EWM55_RS12035	COG0701	Predicted permease
EWM55_RS12040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EWM55_RS12045	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EWM55_RS12050	COG0488	(ABC) transporter
EWM55_RS12055	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EWM55_RS12070	COG0395	ABC-type sugar transport system, permease component
EWM55_RS12090	COG2207	Transcriptional regulator
EWM55_RS12090	COG0662	Cupin 2, conserved barrel domain protein
EWM55_RS12095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS12105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EWM55_RS12110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EWM55_RS12115	COG0584	glycerophosphoryl diester phosphodiesterase
EWM55_RS12125	COG0740	serine-type endopeptidase activity
EWM55_RS12130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EWM55_RS12140	COG1132	(ABC) transporter
EWM55_RS12150	COG5503	Protein of unknown function (DUF1447)
EWM55_RS12165	COG1278	Cold shock
EWM55_RS12170	COG2003	Belongs to the UPF0758 family
EWM55_RS12175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS12180	COG0285	dihydrofolate synthase activity
EWM55_RS12185	COG0525	valine-tRNA ligase activity
EWM55_RS12190	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EWM55_RS12195	COG0301	tRNA thio-modification
EWM55_RS12200	COG1104	cysteine desulfurase activity
EWM55_RS12205	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EWM55_RS12215	COG0561	phosphatase activity
EWM55_RS12220	COG1801	Protein of unknown function DUF72
EWM55_RS12240	COG3579	cysteine-type endopeptidase activity
EWM55_RS12315	COG1098	S1 RNA binding domain
EWM55_RS12320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EWM55_RS12335	COG0492	ferredoxin-NADP+ reductase activity
EWM55_RS12340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EWM55_RS12355	COG4470	Protein conserved in bacteria
EWM55_RS12360	COG0737	Belongs to the 5'-nucleotidase family
EWM55_RS12375	COG0590	tRNA wobble adenosine to inosine editing
EWM55_RS12380	COG2508	Transcriptional regulator
EWM55_RS12390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EWM55_RS12390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EWM55_RS12405	COG2738	Putative neutral zinc metallopeptidase
EWM55_RS12410	COG2824	Alkylphosphonate utilization operon protein PhnA
EWM55_RS12415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EWM55_RS12420	COG4109	DRTGG domain
EWM55_RS12425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EWM55_RS12445	COG0577	efflux transmembrane transporter activity
EWM55_RS12450	COG1136	(ABC) transporter
EWM55_RS12460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EWM55_RS12465	COG1288	antiporter activity
EWM55_RS12470	COG4821	SIS domain
EWM55_RS12490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EWM55_RS12495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EWM55_RS12505	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS12510	COG3715	PTS system
EWM55_RS12535	COG1132	(ABC) transporter
EWM55_RS12540	COG1132	(ABC) transporter
EWM55_RS12555	COG1803	Methylglyoxal synthase
EWM55_RS12560	COG3842	ATPase activity
EWM55_RS12570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EWM55_RS12575	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EWM55_RS12580	COG0084	hydrolase, TatD family'
EWM55_RS12585	COG0531	amino acid
EWM55_RS12595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EWM55_RS12595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EWM55_RS12615	COG0675	Transposase, IS605 OrfB family
EWM55_RS12620	COG4608	Belongs to the ABC transporter superfamily
EWM55_RS12625	COG0444	Belongs to the ABC transporter superfamily
EWM55_RS12630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EWM55_RS12635	COG0601	transmembrane transport
EWM55_RS12645	COG4166	transmembrane transport
EWM55_RS12670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EWM55_RS12675	COG1280	lysine exporter protein (LysE YggA)
EWM55_RS12675	COG1674	ftsk spoiiie
EWM55_RS12680	COG2723	6-phospho-beta-galactosidase activity
EWM55_RS12690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EWM55_RS12695	COG1126	abc transporter atp-binding protein
EWM55_RS12700	COG0765	amino acid transport
EWM55_RS12740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EWM55_RS12750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EWM55_RS12755	COG0009	L-threonylcarbamoyladenylate synthase
EWM55_RS12765	COG2890	protein-(glutamine-N5) methyltransferase activity
EWM55_RS12770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EWM55_RS12775	COG1435	thymidine kinase activity
EWM55_RS12785	COG2226	methyltransferase
EWM55_RS12790	COG0681	Belongs to the peptidase S26 family
EWM55_RS12810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EWM55_RS12815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EWM55_RS12820	COG3442	glutamine amidotransferase
EWM55_RS12825	COG0246	Mannitol dehydrogenase
EWM55_RS12830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS12835	COG2213	PTS system mannitol-specific
EWM55_RS12840	COG1131	(ABC) transporter
EWM55_RS12850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS12855	COG3711	transcriptional antiterminator
EWM55_RS12860	COG2213	PTS system mannitol-specific
EWM55_RS12865	COG1482	cell wall glycoprotein biosynthetic process
EWM55_RS12890	COG1132	(ABC) transporter
EWM55_RS12910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EWM55_RS12915	COG0628	permease
EWM55_RS12925	COG2706	6-phosphogluconolactonase activity
EWM55_RS12935	COG1368	sulfuric ester hydrolase activity
EWM55_RS12950	COG2160	L-arabinose isomerase activity
EWM55_RS12955	COG0235	Class ii aldolase
EWM55_RS12975	COG3940	Belongs to the glycosyl hydrolase 43 family
EWM55_RS12980	COG3534	alpha-L-arabinofuranosidase
EWM55_RS12990	COG0395	ABC-type sugar transport system, permease component
EWM55_RS12995	COG1175	transmembrane transport
EWM55_RS13015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EWM55_RS13020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EWM55_RS13035	COG0789	Transcriptional regulator
EWM55_RS13040	COG1609	Transcriptional regulator
EWM55_RS13055	COG0459	protein refolding
EWM55_RS13060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EWM55_RS13070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS13075	COG2910	NAD(P)H-binding
EWM55_RS13080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EWM55_RS13095	COG5002	protein histidine kinase activity
EWM55_RS13100	COG0745	RESPONSE REGULATOR receiver
EWM55_RS13105	COG1307	EDD domain protein, DegV family
EWM55_RS13175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EWM55_RS13180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EWM55_RS13195	COG0628	permease
EWM55_RS13200	COG1285	pathogenesis
EWM55_RS13205	COG0363	glucosamine-6-phosphate deaminase activity
EWM55_RS13210	COG0488	(ABC) transporter
EWM55_RS13235	COG0222	ribosome binding
EWM55_RS13240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EWM55_RS13245	COG0081	regulation of translation
EWM55_RS13250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EWM55_RS13255	COG1760	l-serine dehydratase
EWM55_RS13260	COG1760	l-serine dehydratase
EWM55_RS13265	COG1304	FMN binding
EWM55_RS13270	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EWM55_RS13275	COG0250	Participates in transcription elongation, termination and antitermination
EWM55_RS13280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EWM55_RS13285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EWM55_RS13300	COG1597	lipid kinase activity
EWM55_RS13315	COG1131	(ABC) transporter
EWM55_RS13320	COG4585	Histidine kinase
EWM55_RS13325	COG2197	response regulator
EWM55_RS13335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EWM55_RS13345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EWM55_RS13350	COG2226	methyltransferase
EWM55_RS13355	COG3142	Participates in the control of copper homeostasis
EWM55_RS13360	COG2239	Acts as a magnesium transporter
EWM55_RS13365	COG0564	pseudouridine synthase activity
EWM55_RS13370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EWM55_RS13375	COG2357	RelA SpoT domain protein
EWM55_RS13380	COG4116	CYTH
EWM55_RS13405	COG4862	establishment of competence for transformation
EWM55_RS13410	COG1393	Belongs to the ArsC family
EWM55_RS13425	COG0419	ATPase involved in DNA repair
EWM55_RS13430	COG0420	3'-5' exonuclease activity
EWM55_RS13435	COG0204	Acyl-transferase
EWM55_RS13440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EWM55_RS13445	COG2827	Endonuclease containing a URI domain
EWM55_RS13450	COG2755	lipolytic protein G-D-S-L family
EWM55_RS13450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EWM55_RS13455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EWM55_RS13460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EWM55_RS13465	COG0124	histidyl-tRNA synthetase
EWM55_RS13475	COG0667	Aldo Keto reductase
EWM55_RS13480	COG2124	cytochrome p450
EWM55_RS13485	COG1490	D-aminoacyl-tRNA deacylase activity
EWM55_RS13490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EWM55_RS13500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EWM55_RS13505	COG2264	protein methyltransferase activity
EWM55_RS13515	COG2094	Belongs to the DNA glycosylase MPG family
EWM55_RS13520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EWM55_RS13535	COG0589	response to stress
EWM55_RS13550	COG0488	(ABC) transporter
EWM55_RS13555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EWM55_RS13560	COG0827	DNA restriction-modification system
EWM55_RS13585	COG4537	Required for transformation and DNA binding
EWM55_RS13590	COG1459	type II secretion system
EWM55_RS13595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EWM55_RS13600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EWM55_RS13605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EWM55_RS13615	COG4473	ABC transporter
EWM55_RS13620	COG1131	(ABC) transporter
EWM55_RS13625	COG0537	adenosine 5'-monophosphoramidase activity
EWM55_RS13635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EWM55_RS13640	COG3481	metal-dependent phosphohydrolase, HD sub domain
EWM55_RS13645	COG4717	serine-type aminopeptidase activity
EWM55_RS13650	COG0420	3'-5' exonuclease activity
EWM55_RS13660	COG0561	phosphatase activity
EWM55_RS13695	COG2211	Major facilitator Superfamily
EWM55_RS13700	COG3507	Belongs to the glycosyl hydrolase 43 family
EWM55_RS13715	COG1073	alpha beta
EWM55_RS13725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EWM55_RS13730	COG1653	transport
EWM55_RS13740	COG4209	transmembrane transport
EWM55_RS13745	COG0395	ABC-type sugar transport system, permease component
EWM55_RS13755	COG2207	Transcriptional regulator
EWM55_RS13760	COG1609	Transcriptional regulator
EWM55_RS13765	COG0246	Mannitol dehydrogenase
EWM55_RS13770	COG2721	sulfolactate sulfo-lyase activity
EWM55_RS13775	COG1904	glucuronate isomerase
EWM55_RS13780	COG2755	lipolytic protein G-D-S-L family
EWM55_RS13790	COG1132	(ABC) transporter
EWM55_RS13795	COG3679	Belongs to the UPF0342 family
EWM55_RS13800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EWM55_RS13805	COG0564	pseudouridine synthase activity
EWM55_RS13815	COG1940	carbohydrate kinase activity
EWM55_RS13820	COG0383	alpha-mannosidase activity
EWM55_RS13845	COG4753	response regulator
EWM55_RS13845	COG2207	Transcriptional regulator
EWM55_RS13850	COG2972	Histidine kinase
EWM55_RS13865	COG1653	transport
EWM55_RS13870	COG0395	ABC-type sugar transport system, permease component
EWM55_RS13875	COG1175	transmembrane transport
EWM55_RS13885	COG1187	pseudouridine synthase activity
EWM55_RS13890	COG2244	polysaccharide biosynthetic process
EWM55_RS13900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EWM55_RS13905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EWM55_RS13920	COG3711	transcriptional antiterminator
EWM55_RS13920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EWM55_RS13970	COG4978	Transcriptional regulator
EWM55_RS13970	COG0789	Transcriptional regulator
EWM55_RS13980	COG1132	(ABC) transporter
EWM55_RS13995	COG0495	leucyl-tRNA aminoacylation
EWM55_RS14000	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS14000	COG1388	LysM domain
EWM55_RS14005	COG0671	phosphoesterase, PA-phosphatase related
EWM55_RS14010	COG1242	4 iron, 4 sulfur cluster binding
EWM55_RS14015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EWM55_RS14060	COG0582	viral genome integration into host DNA
EWM55_RS14065	COG3328	transposase activity
EWM55_RS14080	COG1132	(ABC) transporter
EWM55_RS14085	COG1132	(ABC) transporter
EWM55_RS14100	COG0477	Major facilitator Superfamily
EWM55_RS14105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EWM55_RS14265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EWM55_RS14270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EWM55_RS14275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EWM55_RS14285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EWM55_RS14290	COG0037	tRNA processing
EWM55_RS14295	COG1098	S1 RNA binding domain
EWM55_RS14305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EWM55_RS14310	COG2244	polysaccharide biosynthetic process
EWM55_RS14315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EWM55_RS14320	COG0193	aminoacyl-tRNA hydrolase activity
EWM55_RS14325	COG0039	L-malate dehydrogenase activity
EWM55_RS14335	COG0217	transcriptional regulatory protein
EWM55_RS14360	COG1792	Involved in formation and maintenance of cell shape
EWM55_RS14370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EWM55_RS14375	COG1162	GTPase activity
EWM55_RS14380	COG0515	serine threonine protein kinase
EWM55_RS14380	COG2815	serine threonine protein kinase
EWM55_RS14385	COG0631	protein serine/threonine phosphatase activity
EWM55_RS14390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EWM55_RS14390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EWM55_RS14395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EWM55_RS14400	COG0242	peptide deformylase activity
EWM55_RS14405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EWM55_RS14410	COG1758	RNA polymerase activity
EWM55_RS14415	COG0194	GDP metabolic process
EWM55_RS14440	COG1561	YicC-like family, N-terminal region
EWM55_RS14450	COG1752	Esterase of the alpha-beta hydrolase superfamily
EWM55_RS14470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EWM55_RS14475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EWM55_RS14480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EWM55_RS14485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EWM55_RS14490	COG1121	(ABC) transporter
EWM55_RS14495	COG3443	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS14495	COG0803	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS14500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EWM55_RS14505	COG0392	lysyltransferase activity
EWM55_RS14505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EWM55_RS14510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EWM55_RS14515	COG1418	mRNA catabolic process
EWM55_RS14520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EWM55_RS14525	COG1546	Belongs to the CinA family
EWM55_RS14525	COG1058	Belongs to the CinA family
EWM55_RS14530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EWM55_RS14540	COG1426	Protein conserved in bacteria
EWM55_RS14545	COG0612	Peptidase, M16
EWM55_RS14550	COG0612	Peptidase, M16
EWM55_RS14555	COG1970	mechanosensitive ion channel activity
EWM55_RS14560	COG2153	protein acetylation
EWM55_RS14565	COG4466	Protein conserved in bacteria
EWM55_RS14575	COG3688	RNA-binding protein containing a PIN domain
EWM55_RS14580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EWM55_RS14585	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EWM55_RS14590	COG0215	cysteine-tRNA ligase activity
EWM55_RS14595	COG1045	serine acetyltransferase
EWM55_RS14600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EWM55_RS14605	COG4956	integral membrane protein (PIN domain superfamily)
EWM55_RS14615	COG0756	dUTP diphosphatase activity
EWM55_RS14625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EWM55_RS14630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EWM55_RS14680	COG0778	Nitroreductase
EWM55_RS14690	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS14690	COG1388	LysM domain
EWM55_RS14695	COG4221	oxidoreductase activity
EWM55_RS14705	COG0583	DNA-binding transcription factor activity
EWM55_RS14710	COG3711	transcriptional antiterminator
EWM55_RS14715	COG1263	PTS System
EWM55_RS14715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EWM55_RS14715	COG2190	(PTS) system
EWM55_RS14720	COG0702	epimerase
EWM55_RS14735	COG2207	Transcriptional regulator
EWM55_RS14735	COG3708	Transcriptional regulator
EWM55_RS14755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EWM55_RS14765	COG0604	alcohol dehydrogenase
EWM55_RS14780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EWM55_RS14790	COG0842	Transport permease protein
EWM55_RS14795	COG1131	(ABC) transporter
EWM55_RS14805	COG2205	protein histidine kinase activity
EWM55_RS14810	COG0745	RESPONSE REGULATOR receiver
EWM55_RS14945	COG1674	ftsk spoiiie
EWM55_RS14970	COG2946	Replication initiation factor
EWM55_RS15010	COG0741	lytic transglycosylase activity
EWM55_RS15010	COG0791	NLP P60 protein
EWM55_RS15035	COG2814	Major facilitator Superfamily
EWM55_RS15045	COG3942	CHAP domain
EWM55_RS15045	COG1705	Flagellar rod assembly protein muramidase FlgJ
EWM55_RS15050	COG0446	pyridine nucleotide-disulphide oxidoreductase
EWM55_RS15065	COG2207	Transcriptional regulator
EWM55_RS15065	COG3708	Transcriptional regulator
EWM55_RS15115	COG0523	cobalamin synthesis protein
EWM55_RS15135	COG3443	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS15135	COG0803	Belongs to the bacterial solute-binding protein 9 family
EWM55_RS15150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EWM55_RS15160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EWM55_RS15165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EWM55_RS15170	COG1132	(ABC) transporter
EWM55_RS15175	COG1132	(ABC) transporter
EWM55_RS15185	COG1129	ABC transporter
EWM55_RS15195	COG1309	transcriptional regulator
EWM55_RS15220	COG3344	reverse transcriptase
EWM55_RS15265	COG1378	Sugar-specific transcriptional regulator TrmB
EWM55_RS15280	COG4974	Belongs to the 'phage' integrase family
EWM55_RS15285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EWM55_RS15290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EWM55_RS15295	COG0783	Belongs to the Dps family
EWM55_RS15300	COG1070	Carbohydrate kinase
EWM55_RS15305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EWM55_RS15310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EWM55_RS15315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS15325	COG1554	hydrolase, family 65, central catalytic
EWM55_RS15330	COG0673	inositol 2-dehydrogenase activity
EWM55_RS15335	COG1082	Xylose isomerase domain protein TIM barrel
EWM55_RS15340	COG1063	alcohol dehydrogenase
EWM55_RS15345	COG0395	ABC-type sugar transport system, permease component
EWM55_RS15350	COG1175	transmembrane transport
EWM55_RS15355	COG1653	transport
EWM55_RS15360	COG0366	Alpha amylase catalytic
EWM55_RS15365	COG1609	Transcriptional regulator
EWM55_RS15370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EWM55_RS15375	COG0085	RNA polymerase activity
EWM55_RS15390	COG4120	Belongs to the binding-protein-dependent transport system permease family
EWM55_RS15405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EWM55_RS15405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EWM55_RS15420	COG0142	geranyltranstransferase activity
EWM55_RS15440	COG4939	FMN-binding domain protein
EWM55_RS15460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EWM55_RS15465	COG0826	peptidase U32
EWM55_RS15470	COG0826	peptidase U32
EWM55_RS15475	COG0542	response to heat
EWM55_RS15480	COG4463	regulation of RNA biosynthetic process
EWM55_RS15560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EWM55_RS15570	COG0516	GMP reductase activity
EWM55_RS15570	COG0517	IMP dehydrogenase activity
EWM55_RS15585	COG0012	GTP binding
EWM55_RS15590	COG4481	Protein conserved in bacteria
EWM55_RS15595	COG1475	DNA binding
EWM55_RS15600	COG1192	Involved in chromosome partitioning
EWM55_RS15605	COG0357	Ribosomal RNA small subunit methyltransferase G
EWM55_RS15610	COG0445	tRNA wobble uridine modification
EWM55_RS15615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EWM55_RS15625	COG1847	R3H domain protein
EWM55_RS15630	COG0706	membrane insertase activity
EWM55_RS15635	COG0594	ribonuclease P activity
EWM55_RS15640	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EWM55_RS15780	COG3344	reverse transcriptase
EWM55_RS15860	COG0629	single-stranded DNA binding
EWM55_RS15865	COG0629	single-stranded DNA binding
EWM55_RS15930	COG4974	Belongs to the 'phage' integrase family
EWM55_RS15955	COG3328	transposase activity
EWM55_RS16070	COG4974	Belongs to the 'phage' integrase family
EWM55_RS16095	COG0366	Alpha amylase catalytic
EWM55_RS16100	COG0366	Alpha amylase catalytic
EWM55_RS16110	COG0395	ABC-type sugar transport system, permease component
EWM55_RS16115	COG1175	transmembrane transport
EWM55_RS16120	COG1653	transport
EWM55_RS16125	COG1486	melibiose metabolic process
EWM55_RS16130	COG0395	ABC-type sugar transport system, permease component
EWM55_RS16145	COG1609	Transcriptional regulator
EWM55_RS16150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EWM55_RS16160	COG0346	lactoylglutathione lyase activity
EWM55_RS16170	COG0582	viral genome integration into host DNA
EWM55_RS16175	COG3328	transposase activity
EWM55_RS16290	COG1940	carbohydrate kinase activity
EWM55_RS16300	COG0395	ABC-type sugar transport system, permease component
EWM55_RS16305	COG1175	transmembrane transport
EWM55_RS16315	COG1609	Transcriptional regulator
EWM55_RS16365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EWM55_RS16395	COG3976	FMN-binding domain protein
EWM55_RS16395	COG0431	NADPH-dependent FMN reductase
EWM55_RS16395	COG1053	succinate dehydrogenase
EWM55_RS16415	COG1288	antiporter activity
EWM55_RS16435	COG2188	Transcriptional regulator
EWM55_RS16440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EWM55_RS16445	COG2222	sugar isomerase
EWM55_RS16490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EWM55_RS16495	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EWM55_RS16495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EWM55_RS16500	COG2222	sugar isomerase
EWM55_RS16505	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS16510	COG3715	PTS system
EWM55_RS16555	COG3328	transposase activity
EWM55_RS16580	COG3716	PTS system mannose fructose sorbose family IID component
EWM55_RS16585	COG3715	PTS system
EWM55_RS16605	COG2188	Transcriptional regulator
EWM55_RS16610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EWM55_RS16690	COG0629	single-stranded DNA binding
EWM55_RS16925	COG1192	Involved in chromosome partitioning
EWM55_RS16945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EWM55_RS16960	COG4115	mRNA cleavage
EWM55_RS17085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EWM55_RS17100	COG3409	Peptidoglycan-binding domain 1 protein
EWM55_RS17145	COG5002	protein histidine kinase activity
EWM55_RS17165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EWM55_RS17180	COG3842	ATPase activity
EWM55_RS17190	COG0395	ABC-type sugar transport system, permease component
EWM55_RS17205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EWM55_RS17230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EWM55_RS17235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EWM55_RS17255	COG1136	(ABC) transporter
EWM55_RS17275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EWM55_RS17355	COG2207	Transcriptional regulator