locus-tag	class	description
CDW54_RS00010	COG0765	amino acid transport
CDW54_RS00015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDW54_RS00020	COG1126	abc transporter atp-binding protein
CDW54_RS00030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDW54_RS00030	COG0072	phenylalanine-tRNA ligase activity
CDW54_RS00035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDW54_RS00040	COG1733	regulation of RNA biosynthetic process
CDW54_RS00045	COG1074	ATP-dependent DNA helicase activity
CDW54_RS00050	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CDW54_RS00055	COG3104	oligopeptide transport
CDW54_RS00075	COG4990	cell redox homeostasis
CDW54_RS00140	COG3942	CHAP domain
CDW54_RS00140	COG1388	LysM domain
CDW54_RS00155	COG2151	metal-sulfur cluster biosynthetic enzyme
CDW54_RS00160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDW54_RS00165	COG1666	GTP binding
CDW54_RS00185	COG1968	undecaprenyl-diphosphatase activity
CDW54_RS00190	COG2217	Heavy metal translocating P-type atpase
CDW54_RS00195	COG2707	UPF0756 membrane protein
CDW54_RS00205	COG0268	Binds directly to 16S ribosomal RNA
CDW54_RS00210	COG1466	dna polymerase III delta subunit
CDW54_RS00220	COG2131	deaminase
CDW54_RS00235	COG1596	polysaccharide export
CDW54_RS00235	COG1555	photosystem II stabilization
CDW54_RS00240	COG3480	Lon protease (S16) C-terminal proteolytic domain
CDW54_RS00245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDW54_RS00250	COG0742	ribosomal rna small subunit methyltransferase
CDW54_RS00255	COG4471	UPF0298 protein
CDW54_RS00270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDW54_RS00275	COG0772	Belongs to the SEDS family
CDW54_RS00280	COG4838	Belongs to the UPF0358 family
CDW54_RS00285	COG0514	ATP-dependent DNA helicase (RecQ)
CDW54_RS00290	COG1217	gtp-binding protein TYPA
CDW54_RS00295	COG0483	inositol monophosphate 1-phosphatase activity
CDW54_RS00300	COG4476	Belongs to the UPF0223 family
CDW54_RS00315	COG0022	dehydrogenase e1 component
CDW54_RS00330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDW54_RS00340	COG0516	GMP reductase activity
CDW54_RS00345	COG4214	carbohydrate transport
CDW54_RS00355	COG4213	ABC transporter substrate-binding protein
CDW54_RS00360	COG1879	ABC-type sugar transport system periplasmic component
CDW54_RS00375	COG4989	oxidoreductase activity
CDW54_RS00380	COG0151	Belongs to the GarS family
CDW54_RS00385	COG0138	bifunctional purine biosynthesis protein purh
CDW54_RS00390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDW54_RS00395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDW54_RS00405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDW54_RS00410	COG0047	phosphoribosylformylglycinamidine synthase activity
CDW54_RS00415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDW54_RS00420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDW54_RS00430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDW54_RS00435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDW54_RS00440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDW54_RS00450	COG2233	PERMEase
CDW54_RS00455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDW54_RS00460	COG0673	inositol 2-dehydrogenase activity
CDW54_RS00470	COG0395	ABC-type sugar transport system, permease component
CDW54_RS00475	COG1175	transmembrane transport
CDW54_RS00480	COG1653	transport
CDW54_RS00495	COG1876	peptidase activity
CDW54_RS00505	COG0673	inositol 2-dehydrogenase activity
CDW54_RS00525	COG2268	Band 7 protein
CDW54_RS00535	COG3290	protein histidine kinase activity
CDW54_RS00540	COG4565	transcriptional regulatory protein
CDW54_RS00545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDW54_RS00565	COG0436	Aminotransferase
CDW54_RS00585	COG0346	lactoylglutathione lyase activity
CDW54_RS00600	COG1388	LysM domain
CDW54_RS00600	COG3942	CHAP domain
CDW54_RS00605	COG0084	hydrolase, TatD family'
CDW54_RS00610	COG1116	anion transmembrane transporter activity
CDW54_RS00620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDW54_RS00635	COG1732	Glycine betaine
CDW54_RS00655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDW54_RS00665	COG1609	Transcriptional regulator
CDW54_RS00670	COG1073	alpha beta
CDW54_RS00680	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CDW54_RS00700	COG1227	inorganic diphosphatase activity
CDW54_RS00705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDW54_RS00710	COG1882	Formate acetyltransferase
CDW54_RS00720	COG0187	DNA topoisomerase II activity
CDW54_RS00725	COG1832	CoA-binding protein
CDW54_RS00730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDW54_RS00745	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDW54_RS00750	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDW54_RS00755	COG4974	Belongs to the 'phage' integrase family
CDW54_RS00760	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDW54_RS00765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDW54_RS00770	COG0758	DNA mediated transformation
CDW54_RS00780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDW54_RS00785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDW54_RS00810	COG0681	Belongs to the peptidase S26 family
CDW54_RS00815	COG4479	Belongs to the UPF0346 family
CDW54_RS00825	COG4698	Protein conserved in bacteria
CDW54_RS00830	COG2755	lipolytic protein G-D-S-L family
CDW54_RS00835	COG1307	EDD domain protein, DegV family
CDW54_RS00840	COG1272	protein, Hemolysin III
CDW54_RS00850	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDW54_RS00855	COG0488	(ABC) transporter
CDW54_RS00860	COG0025	NhaP-type Na H and K H
CDW54_RS00875	COG0617	tRNA 3'-terminal CCA addition
CDW54_RS00880	COG1694	Mazg nucleotide pyrophosphohydrolase
CDW54_RS00885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDW54_RS00890	COG5582	Belongs to the UPF0302 family
CDW54_RS00895	COG0457	Tetratricopeptide repeat
CDW54_RS00910	COG0776	regulation of translation
CDW54_RS00915	COG1160	GTP binding
CDW54_RS00920	COG0539	negative regulation of cytoplasmic translation
CDW54_RS00925	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDW54_RS00935	COG0514	ATP-dependent DNA helicase (RecQ)
CDW54_RS00955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDW54_RS00960	COG1288	antiporter activity
CDW54_RS00965	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CDW54_RS00970	COG1187	pseudouridine synthase activity
CDW54_RS00975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDW54_RS00980	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDW54_RS00990	COG4974	Belongs to the 'phage' integrase family
CDW54_RS00995	COG0735	belongs to the Fur family
CDW54_RS01000	COG2996	Protein conserved in bacteria
CDW54_RS01010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDW54_RS01015	COG0358	DNA primase activity
CDW54_RS01020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDW54_RS01030	COG0741	lytic transglycosylase activity
CDW54_RS01035	COG0596	Alpha beta hydrolase
CDW54_RS01040	COG0392	lysyltransferase activity
CDW54_RS01040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDW54_RS01060	COG0656	L-ascorbic acid biosynthetic process
CDW54_RS01075	COG0183	Belongs to the thiolase family
CDW54_RS01080	COG3425	synthase
CDW54_RS01090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDW54_RS01095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDW54_RS01100	COG0351	phosphomethylpyrimidine kinase
CDW54_RS01115	COG1393	Belongs to the ArsC family
CDW54_RS01135	COG0589	response to stress
CDW54_RS01140	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS01145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS01150	COG2188	Transcriptional regulator
CDW54_RS01160	COG0346	lactoylglutathione lyase activity
CDW54_RS01165	COG0400	carboxylic ester hydrolase activity
CDW54_RS01185	COG3623	hexulose-6-phosphate isomerase
CDW54_RS01190	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CDW54_RS01215	COG1349	DNA-binding transcription factor activity
CDW54_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS01245	COG1263	PTS System
CDW54_RS01245	COG2190	(PTS) system
CDW54_RS01245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS01250	COG1486	melibiose metabolic process
CDW54_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS01255	COG2190	(PTS) system
CDW54_RS01255	COG1263	PTS System
CDW54_RS01265	COG3711	transcriptional antiterminator
CDW54_RS01375	COG5002	protein histidine kinase activity
CDW54_RS01380	COG0745	RESPONSE REGULATOR receiver
CDW54_RS01385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDW54_RS01390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDW54_RS01400	COG0583	DNA-binding transcription factor activity
CDW54_RS01410	COG0205	6-phosphofructokinase activity
CDW54_RS01415	COG0587	DNA-directed DNA polymerase activity
CDW54_RS01425	COG2814	Major facilitator Superfamily
CDW54_RS01430	COG2252	PERMEase
CDW54_RS01435	COG0561	phosphatase activity
CDW54_RS01440	COG0768	penicillin binding
CDW54_RS01445	COG1737	Transcriptional regulator
CDW54_RS01450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDW54_RS01460	COG1942	4-Oxalocrotonate Tautomerase
CDW54_RS01465	COG2217	Heavy metal translocating P-type atpase
CDW54_RS01470	COG3973	AAA domain
CDW54_RS01480	COG0217	transcriptional regulatory protein
CDW54_RS01485	COG1323	Belongs to the UPF0348 family
CDW54_RS01490	COG2226	methyltransferase
CDW54_RS01495	COG0799	negative regulation of ribosome biogenesis
CDW54_RS01500	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDW54_RS01505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDW54_RS01510	COG1534	Rna-binding protein
CDW54_RS01515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDW54_RS01520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CDW54_RS01525	COG0825	malonyl-CoA metabolic process
CDW54_RS01530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDW54_RS01535	COG0439	Biotin carboxylase
CDW54_RS01540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDW54_RS01550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDW54_RS01560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDW54_RS01570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDW54_RS01575	COG1846	Transcriptional regulator
CDW54_RS01580	COG0322	excinuclease ABC activity
CDW54_RS01585	COG4703	Protein of unknown function (DUF1797)
CDW54_RS01590	COG2084	Dehydrogenase
CDW54_RS01595	COG0438	transferase activity, transferring glycosyl groups
CDW54_RS01605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDW54_RS01610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS01615	COG0542	response to heat
CDW54_RS01635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDW54_RS01645	COG1253	flavin adenine dinucleotide binding
CDW54_RS01650	COG0628	permease
CDW54_RS01670	COG3557	Belongs to the UPF0374 family
CDW54_RS01675	COG1194	a g-specific adenine glycosylase
CDW54_RS01680	COG2137	regulation of response to DNA damage stimulus
CDW54_RS01685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDW54_RS01690	COG3397	chitin binding
CDW54_RS01695	COG3328	transposase activity
CDW54_RS01700	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDW54_RS01705	COG1316	TRANSCRIPTIONal
CDW54_RS01715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDW54_RS01720	COG2246	polysaccharide biosynthetic process
CDW54_RS01745	COG0569	domain protein
CDW54_RS01755	COG4585	Histidine kinase
CDW54_RS01765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDW54_RS01770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDW54_RS01795	COG3475	LICD family
CDW54_RS01805	COG1216	Glycosyl transferase, family 2
CDW54_RS01820	COG3475	LICD family
CDW54_RS01825	COG1216	Glycosyl transferase, family 2
CDW54_RS01830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDW54_RS01835	COG0438	transferase activity, transferring glycosyl groups
CDW54_RS01835	COG1216	Glycosyl transferase, family 2
CDW54_RS01840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDW54_RS01850	COG1682	transport, permease protein
CDW54_RS01865	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDW54_RS01870	COG1088	dTDP-glucose 4,6-dehydratase activity
CDW54_RS01880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDW54_RS01885	COG1215	transferase activity, transferring glycosyl groups
CDW54_RS01900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDW54_RS01905	COG1295	ribonuclease BN
CDW54_RS01910	COG0024	Methionine aminopeptidase
CDW54_RS01915	COG0716	FMN binding
CDW54_RS01925	COG2309	aminopeptidase activity
CDW54_RS01965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS01970	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDW54_RS01975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS01980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDW54_RS01980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDW54_RS01985	COG0513	Belongs to the DEAD box helicase family
CDW54_RS01990	COG0673	inositol 2-dehydrogenase activity
CDW54_RS02010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDW54_RS02015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDW54_RS02020	COG3599	regulation of cell shape
CDW54_RS02025	COG2302	S4 RNA-binding domain
CDW54_RS02035	COG1799	cell septum assembly
CDW54_RS02040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDW54_RS02075	COG0768	penicillin binding
CDW54_RS02110	COG0497	DNA recombination
CDW54_RS02115	COG1438	arginine binding
CDW54_RS02120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDW54_RS02130	COG1722	exodeoxyribonuclease VII activity
CDW54_RS02135	COG1570	exodeoxyribonuclease VII activity
CDW54_RS02140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDW54_RS02145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDW54_RS02150	COG1302	Protein conserved in bacteria
CDW54_RS02155	COG0006	proline dipeptidase activity
CDW54_RS02160	COG2261	transglycosylase associated protein
CDW54_RS02170	COG3716	PTS system mannose fructose sorbose family IID component
CDW54_RS02175	COG3715	PTS system
CDW54_RS02185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS02185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS02190	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDW54_RS02190	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDW54_RS02195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDW54_RS02205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDW54_RS02215	COG0659	secondary active sulfate transmembrane transporter activity
CDW54_RS02220	COG3759	membrane
CDW54_RS02245	COG0095	Lipoate-protein ligase
CDW54_RS02250	COG1234	tRNA 3'-trailer cleavage
CDW54_RS02260	COG1363	Peptidase, m42
CDW54_RS02265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CDW54_RS02270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDW54_RS02275	COG1696	Membrane protein involved in D-alanine export
CDW54_RS02280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDW54_RS02295	COG0577	efflux transmembrane transporter activity
CDW54_RS02300	COG1136	(ABC) transporter
CDW54_RS02305	COG1328	CTP reductase activity
CDW54_RS02310	COG0602	queuosine metabolic process
CDW54_RS02325	COG4467	Involved in initiation control of chromosome replication
CDW54_RS02330	COG1774	PSP1 C-terminal conserved region
CDW54_RS02335	COG0470	DNA polymerase III
CDW54_RS02340	COG3870	Protein conserved in bacteria
CDW54_RS02345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDW54_RS02350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDW54_RS02355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDW54_RS02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDW54_RS02385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDW54_RS02395	COG2814	Major facilitator Superfamily
CDW54_RS02405	COG1349	DNA-binding transcription factor activity
CDW54_RS02415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDW54_RS02415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDW54_RS02430	COG0254	rRNA binding
CDW54_RS02435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDW54_RS02440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDW54_RS02445	COG1876	peptidase activity
CDW54_RS02470	COG0504	CTP synthase activity
CDW54_RS02485	COG0789	Transcriptional regulator
CDW54_RS02490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDW54_RS02495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDW54_RS02500	COG0584	glycerophosphoryl diester phosphodiesterase
CDW54_RS02510	COG0740	serine-type endopeptidase activity
CDW54_RS02515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDW54_RS02525	COG1132	(ABC) transporter
CDW54_RS02535	COG5503	Protein of unknown function (DUF1447)
CDW54_RS02550	COG1278	Cold shock
CDW54_RS02555	COG2003	Belongs to the UPF0758 family
CDW54_RS02560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS02565	COG0285	dihydrofolate synthase activity
CDW54_RS02570	COG0525	valine-tRNA ligase activity
CDW54_RS02575	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDW54_RS02580	COG0301	tRNA thio-modification
CDW54_RS02585	COG1104	cysteine desulfurase activity
CDW54_RS02590	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CDW54_RS02600	COG0561	phosphatase activity
CDW54_RS02605	COG1801	Protein of unknown function DUF72
CDW54_RS02625	COG3579	cysteine-type endopeptidase activity
CDW54_RS02650	COG3328	transposase activity
CDW54_RS02680	COG3328	transposase activity
CDW54_RS02720	COG1609	Transcriptional regulator
CDW54_RS02725	COG1621	beta-fructofuranosidase activity
CDW54_RS02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS02730	COG1263	PTS System
CDW54_RS02730	COG2190	(PTS) system
CDW54_RS02735	COG1940	carbohydrate kinase activity
CDW54_RS02775	COG1609	Transcriptional regulator
CDW54_RS02780	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDW54_RS02785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS02795	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS02810	COG3328	transposase activity
CDW54_RS02835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS02835	COG2190	(PTS) system
CDW54_RS02835	COG1263	PTS System
CDW54_RS02845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS02905	COG1098	S1 RNA binding domain
CDW54_RS02910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDW54_RS02920	COG0492	ferredoxin-NADP+ reductase activity
CDW54_RS02925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDW54_RS02940	COG4470	Protein conserved in bacteria
CDW54_RS02945	COG0737	Belongs to the 5'-nucleotidase family
CDW54_RS02960	COG0590	tRNA wobble adenosine to inosine editing
CDW54_RS02965	COG2508	Transcriptional regulator
CDW54_RS02975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDW54_RS02975	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDW54_RS02990	COG2738	Putative neutral zinc metallopeptidase
CDW54_RS02995	COG2824	Alkylphosphonate utilization operon protein PhnA
CDW54_RS03000	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDW54_RS03005	COG4109	DRTGG domain
CDW54_RS03010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDW54_RS03030	COG0577	efflux transmembrane transporter activity
CDW54_RS03035	COG1136	(ABC) transporter
CDW54_RS03045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDW54_RS03050	COG1288	antiporter activity
CDW54_RS03060	COG4821	SIS domain
CDW54_RS03075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDW54_RS03080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDW54_RS03085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDW54_RS03090	COG3716	PTS system mannose fructose sorbose family IID component
CDW54_RS03095	COG3715	PTS system
CDW54_RS03125	COG1132	(ABC) transporter
CDW54_RS03130	COG1132	(ABC) transporter
CDW54_RS03140	COG1803	Methylglyoxal synthase
CDW54_RS03145	COG3842	ATPase activity
CDW54_RS03155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDW54_RS03160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDW54_RS03165	COG0084	hydrolase, TatD family'
CDW54_RS03170	COG0531	amino acid
CDW54_RS03180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDW54_RS03180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDW54_RS03200	COG0675	Transposase, IS605 OrfB family
CDW54_RS03205	COG4608	Belongs to the ABC transporter superfamily
CDW54_RS03210	COG0444	Belongs to the ABC transporter superfamily
CDW54_RS03215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDW54_RS03220	COG0601	transmembrane transport
CDW54_RS03230	COG4166	transmembrane transport
CDW54_RS03255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDW54_RS03260	COG1280	lysine exporter protein (LysE YggA)
CDW54_RS03260	COG1674	ftsk spoiiie
CDW54_RS03265	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS03270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDW54_RS03275	COG1126	abc transporter atp-binding protein
CDW54_RS03280	COG0765	amino acid transport
CDW54_RS03300	COG3328	transposase activity
CDW54_RS03330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDW54_RS03340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDW54_RS03345	COG0009	L-threonylcarbamoyladenylate synthase
CDW54_RS03355	COG2890	protein-(glutamine-N5) methyltransferase activity
CDW54_RS03360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDW54_RS03365	COG1435	thymidine kinase activity
CDW54_RS03375	COG2226	methyltransferase
CDW54_RS03380	COG0681	Belongs to the peptidase S26 family
CDW54_RS03400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDW54_RS03405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDW54_RS03410	COG3442	glutamine amidotransferase
CDW54_RS03415	COG0246	Mannitol dehydrogenase
CDW54_RS03420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS03425	COG2213	PTS system mannitol-specific
CDW54_RS03430	COG1131	(ABC) transporter
CDW54_RS03440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS03445	COG3711	transcriptional antiterminator
CDW54_RS03450	COG2213	PTS system mannitol-specific
CDW54_RS03455	COG1482	cell wall glycoprotein biosynthetic process
CDW54_RS03475	COG1132	(ABC) transporter
CDW54_RS03495	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDW54_RS03500	COG0628	permease
CDW54_RS03510	COG2706	6-phosphogluconolactonase activity
CDW54_RS03520	COG1368	sulfuric ester hydrolase activity
CDW54_RS03530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDW54_RS03535	COG2160	L-arabinose isomerase activity
CDW54_RS03540	COG0235	Class ii aldolase
CDW54_RS03560	COG3940	Belongs to the glycosyl hydrolase 43 family
CDW54_RS03565	COG3534	alpha-L-arabinofuranosidase
CDW54_RS03575	COG0395	ABC-type sugar transport system, permease component
CDW54_RS03580	COG1175	transmembrane transport
CDW54_RS03600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDW54_RS03605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDW54_RS03620	COG0789	Transcriptional regulator
CDW54_RS03625	COG1609	Transcriptional regulator
CDW54_RS03635	COG0459	protein refolding
CDW54_RS03640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDW54_RS03650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS03655	COG2910	NAD(P)H-binding
CDW54_RS03660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDW54_RS03675	COG5002	protein histidine kinase activity
CDW54_RS03680	COG0745	RESPONSE REGULATOR receiver
CDW54_RS03685	COG1307	EDD domain protein, DegV family
CDW54_RS03705	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CDW54_RS03720	COG1278	Cold shock
CDW54_RS03740	COG3328	transposase activity
CDW54_RS03750	COG3448	diguanylate cyclase activity
CDW54_RS03750	COG4175	Glycine betaine
CDW54_RS03780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDW54_RS03785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDW54_RS03795	COG0628	permease
CDW54_RS03800	COG1285	pathogenesis
CDW54_RS03805	COG0363	glucosamine-6-phosphate deaminase activity
CDW54_RS03810	COG0488	(ABC) transporter
CDW54_RS03815	COG2814	Major facilitator Superfamily
CDW54_RS03820	COG0398	Pfam SNARE associated Golgi protein
CDW54_RS03825	COG0222	ribosome binding
CDW54_RS03830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDW54_RS03835	COG0081	regulation of translation
CDW54_RS03840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDW54_RS03845	COG1760	l-serine dehydratase
CDW54_RS03850	COG1760	l-serine dehydratase
CDW54_RS03855	COG1304	FMN binding
CDW54_RS03860	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDW54_RS03865	COG0250	Participates in transcription elongation, termination and antitermination
CDW54_RS03870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDW54_RS03875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDW54_RS03890	COG1597	lipid kinase activity
CDW54_RS03905	COG1131	(ABC) transporter
CDW54_RS03910	COG4585	Histidine kinase
CDW54_RS03915	COG2197	response regulator
CDW54_RS03925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDW54_RS03935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDW54_RS03940	COG2226	methyltransferase
CDW54_RS03945	COG3142	Participates in the control of copper homeostasis
CDW54_RS03950	COG2239	Acts as a magnesium transporter
CDW54_RS03955	COG0564	pseudouridine synthase activity
CDW54_RS03960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDW54_RS03965	COG2357	RelA SpoT domain protein
CDW54_RS03970	COG4116	CYTH
CDW54_RS03990	COG4862	establishment of competence for transformation
CDW54_RS03995	COG1393	Belongs to the ArsC family
CDW54_RS04010	COG0419	ATPase involved in DNA repair
CDW54_RS04015	COG0420	3'-5' exonuclease activity
CDW54_RS04020	COG0204	Acyl-transferase
CDW54_RS04025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDW54_RS04030	COG2827	Endonuclease containing a URI domain
CDW54_RS04040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDW54_RS04045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDW54_RS04050	COG0124	histidyl-tRNA synthetase
CDW54_RS04060	COG0667	Aldo Keto reductase
CDW54_RS04065	COG2124	cytochrome p450
CDW54_RS04070	COG1490	D-aminoacyl-tRNA deacylase activity
CDW54_RS04075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDW54_RS04085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDW54_RS04090	COG2264	protein methyltransferase activity
CDW54_RS04100	COG2094	Belongs to the DNA glycosylase MPG family
CDW54_RS04105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDW54_RS04120	COG0589	response to stress
CDW54_RS04135	COG0488	(ABC) transporter
CDW54_RS04140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDW54_RS04145	COG0827	DNA restriction-modification system
CDW54_RS04170	COG4537	Required for transformation and DNA binding
CDW54_RS04175	COG1459	type II secretion system
CDW54_RS04180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDW54_RS04185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDW54_RS04190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDW54_RS04200	COG4473	ABC transporter
CDW54_RS04205	COG1131	(ABC) transporter
CDW54_RS04210	COG0537	adenosine 5'-monophosphoramidase activity
CDW54_RS04220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDW54_RS04225	COG3481	metal-dependent phosphohydrolase, HD sub domain
CDW54_RS04230	COG4717	serine-type aminopeptidase activity
CDW54_RS04235	COG0420	3'-5' exonuclease activity
CDW54_RS04275	COG2211	Major facilitator Superfamily
CDW54_RS04285	COG3507	Belongs to the glycosyl hydrolase 43 family
CDW54_RS04300	COG1073	alpha beta
CDW54_RS04310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDW54_RS04315	COG1653	transport
CDW54_RS04325	COG4209	transmembrane transport
CDW54_RS04330	COG0395	ABC-type sugar transport system, permease component
CDW54_RS04340	COG2207	Transcriptional regulator
CDW54_RS04345	COG1609	Transcriptional regulator
CDW54_RS04350	COG0246	Mannitol dehydrogenase
CDW54_RS04355	COG2721	sulfolactate sulfo-lyase activity
CDW54_RS04360	COG1904	glucuronate isomerase
CDW54_RS04365	COG2755	lipolytic protein G-D-S-L family
CDW54_RS04375	COG1132	(ABC) transporter
CDW54_RS04380	COG3679	Belongs to the UPF0342 family
CDW54_RS04385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDW54_RS04390	COG0564	pseudouridine synthase activity
CDW54_RS04395	COG1940	carbohydrate kinase activity
CDW54_RS04400	COG0383	alpha-mannosidase activity
CDW54_RS04425	COG2207	Transcriptional regulator
CDW54_RS04425	COG4753	response regulator
CDW54_RS04430	COG2972	Histidine kinase
CDW54_RS04440	COG1653	transport
CDW54_RS04445	COG0395	ABC-type sugar transport system, permease component
CDW54_RS04450	COG1175	transmembrane transport
CDW54_RS04460	COG1187	pseudouridine synthase activity
CDW54_RS04465	COG2244	polysaccharide biosynthetic process
CDW54_RS04475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDW54_RS04480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS04495	COG3711	transcriptional antiterminator
CDW54_RS04495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS04535	COG4978	Transcriptional regulator
CDW54_RS04535	COG0789	Transcriptional regulator
CDW54_RS04545	COG1132	(ABC) transporter
CDW54_RS04560	COG0495	leucyl-tRNA aminoacylation
CDW54_RS04565	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDW54_RS04565	COG1388	LysM domain
CDW54_RS04570	COG0671	phosphoesterase, PA-phosphatase related
CDW54_RS04575	COG1242	4 iron, 4 sulfur cluster binding
CDW54_RS04580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDW54_RS04585	COG1132	(ABC) transporter
CDW54_RS04590	COG1132	(ABC) transporter
CDW54_RS04605	COG0477	Major facilitator Superfamily
CDW54_RS04610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDW54_RS04770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDW54_RS04775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDW54_RS04780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDW54_RS04790	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDW54_RS04795	COG0037	tRNA processing
CDW54_RS04800	COG1098	S1 RNA binding domain
CDW54_RS04810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDW54_RS04815	COG2244	polysaccharide biosynthetic process
CDW54_RS04820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDW54_RS04825	COG0193	aminoacyl-tRNA hydrolase activity
CDW54_RS04830	COG0039	L-malate dehydrogenase activity
CDW54_RS04840	COG0217	transcriptional regulatory protein
CDW54_RS04865	COG1792	Involved in formation and maintenance of cell shape
CDW54_RS04875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDW54_RS04880	COG1162	GTPase activity
CDW54_RS04885	COG2815	serine threonine protein kinase
CDW54_RS04885	COG0515	serine threonine protein kinase
CDW54_RS04890	COG0631	protein serine/threonine phosphatase activity
CDW54_RS04895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDW54_RS04895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDW54_RS04900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDW54_RS04905	COG0242	peptide deformylase activity
CDW54_RS04910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDW54_RS04915	COG1758	RNA polymerase activity
CDW54_RS04920	COG0194	GDP metabolic process
CDW54_RS04940	COG1561	YicC-like family, N-terminal region
CDW54_RS04950	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDW54_RS04965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDW54_RS04970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDW54_RS04975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDW54_RS04980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDW54_RS04985	COG1121	(ABC) transporter
CDW54_RS04990	COG3443	Belongs to the bacterial solute-binding protein 9 family
CDW54_RS04990	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDW54_RS04995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDW54_RS05000	COG0392	lysyltransferase activity
CDW54_RS05000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDW54_RS05005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDW54_RS05010	COG1418	mRNA catabolic process
CDW54_RS05015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDW54_RS05020	COG1058	Belongs to the CinA family
CDW54_RS05020	COG1546	Belongs to the CinA family
CDW54_RS05025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDW54_RS05035	COG1426	Protein conserved in bacteria
CDW54_RS05040	COG0612	Peptidase, M16
CDW54_RS05045	COG0612	Peptidase, M16
CDW54_RS05050	COG1970	mechanosensitive ion channel activity
CDW54_RS05055	COG2153	protein acetylation
CDW54_RS05060	COG4466	Protein conserved in bacteria
CDW54_RS05070	COG3688	RNA-binding protein containing a PIN domain
CDW54_RS05075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDW54_RS05080	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CDW54_RS05085	COG0215	cysteine-tRNA ligase activity
CDW54_RS05090	COG1045	serine acetyltransferase
CDW54_RS05095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDW54_RS05100	COG4956	integral membrane protein (PIN domain superfamily)
CDW54_RS05110	COG0756	dUTP diphosphatase activity
CDW54_RS05115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDW54_RS05120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDW54_RS05170	COG0778	Nitroreductase
CDW54_RS05185	COG0604	alcohol dehydrogenase
CDW54_RS05200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDW54_RS05210	COG0842	Transport permease protein
CDW54_RS05215	COG1131	(ABC) transporter
CDW54_RS05225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDW54_RS05230	COG2205	protein histidine kinase activity
CDW54_RS05235	COG0745	RESPONSE REGULATOR receiver
CDW54_RS05255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDW54_RS05260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDW54_RS05265	COG0783	Belongs to the Dps family
CDW54_RS05270	COG1070	Carbohydrate kinase
CDW54_RS05275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDW54_RS05280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDW54_RS05285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS05295	COG1554	hydrolase, family 65, central catalytic
CDW54_RS05300	COG0673	inositol 2-dehydrogenase activity
CDW54_RS05305	COG1082	Xylose isomerase domain protein TIM barrel
CDW54_RS05310	COG1063	alcohol dehydrogenase
CDW54_RS05315	COG0395	ABC-type sugar transport system, permease component
CDW54_RS05320	COG1175	transmembrane transport
CDW54_RS05325	COG1653	transport
CDW54_RS05330	COG0366	Alpha amylase catalytic
CDW54_RS05340	COG1609	Transcriptional regulator
CDW54_RS05345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDW54_RS05350	COG0085	RNA polymerase activity
CDW54_RS05365	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDW54_RS05380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDW54_RS05380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDW54_RS05395	COG0142	geranyltranstransferase activity
CDW54_RS05415	COG4939	FMN-binding domain protein
CDW54_RS05435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDW54_RS05440	COG0826	peptidase U32
CDW54_RS05445	COG0826	peptidase U32
CDW54_RS05450	COG0542	response to heat
CDW54_RS05455	COG4463	regulation of RNA biosynthetic process
CDW54_RS05540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDW54_RS05550	COG0517	IMP dehydrogenase activity
CDW54_RS05550	COG0516	GMP reductase activity
CDW54_RS05560	COG0012	GTP binding
CDW54_RS05565	COG4481	Protein conserved in bacteria
CDW54_RS05570	COG1475	DNA binding
CDW54_RS05575	COG1192	Involved in chromosome partitioning
CDW54_RS05580	COG0357	Ribosomal RNA small subunit methyltransferase G
CDW54_RS05625	COG0582	viral genome integration into host DNA
CDW54_RS05630	COG0445	tRNA wobble uridine modification
CDW54_RS05635	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDW54_RS05645	COG1847	R3H domain protein
CDW54_RS05650	COG0706	membrane insertase activity
CDW54_RS05655	COG0594	ribonuclease P activity
CDW54_RS05660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDW54_RS05670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDW54_RS05675	COG0592	DNA-directed DNA polymerase activity
CDW54_RS05680	COG2501	S4 domain
CDW54_RS05685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDW54_RS05690	COG0187	DNA topoisomerase II activity
CDW54_RS05700	COG0360	Binds together with S18 to 16S ribosomal RNA
CDW54_RS05705	COG0629	single-stranded DNA binding
CDW54_RS05710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDW54_RS05720	COG0359	binds to the 23S rRNA
CDW54_RS05725	COG0305	Participates in initiation and elongation during chromosome replication
CDW54_RS05730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDW54_RS05745	COG0488	(ABC) transporter
CDW54_RS05765	COG0028	Belongs to the TPP enzyme family
CDW54_RS05805	COG0519	Catalyzes the synthesis of GMP from XMP
CDW54_RS05805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDW54_RS05810	COG1072	(Pantothenic acid kinase))
CDW54_RS05815	COG2813	Specifically methylates the guanine in position
CDW54_RS05820	COG1609	Transcriptional regulator
CDW54_RS05825	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CDW54_RS05830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDW54_RS05835	COG0295	cytidine deaminase activity
CDW54_RS05840	COG1744	ABC transporter substrate-binding protein PnrA-like
CDW54_RS05845	COG3845	ABC transporter
CDW54_RS05850	COG4603	Belongs to the binding-protein-dependent transport system permease family
CDW54_RS05855	COG1079	Belongs to the binding-protein-dependent transport system permease family
CDW54_RS05860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDW54_RS05870	COG0813	purine-nucleoside phosphorylase activity
CDW54_RS05880	COG0588	phosphoglycerate mutase activity
CDW54_RS05890	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDW54_RS05895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDW54_RS05900	COG0049	tRNA binding
CDW54_RS05905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDW54_RS05910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDW54_RS05915	COG0051	transcription antitermination factor activity, RNA binding
CDW54_RS05920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDW54_RS05925	COG0088	Forms part of the polypeptide exit tunnel
CDW54_RS05930	COG0089	rRNA binding
CDW54_RS05935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDW54_RS05945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDW54_RS05950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDW54_RS05955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDW54_RS05960	COG0255	Belongs to the universal ribosomal protein uL29 family
CDW54_RS05965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDW54_RS05970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDW54_RS05975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDW54_RS05980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDW54_RS05985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDW54_RS05990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDW54_RS05995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDW54_RS06000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDW54_RS06005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDW54_RS06010	COG1841	ribosomal large subunit assembly
CDW54_RS06015	COG0200	Binds to the 23S rRNA
CDW54_RS06020	COG0201	protein transport
CDW54_RS06025	COG0563	adenylate kinase activity
CDW54_RS06030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDW54_RS06035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDW54_RS06040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDW54_RS06045	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDW54_RS06050	COG0202	RNA polymerase activity
CDW54_RS06055	COG0203	ribosomal protein L17
CDW54_RS06060	COG1122	ATPase activity
CDW54_RS06065	COG1122	ATPase activity
CDW54_RS06075	COG0101	tRNA pseudouridine synthase activity
CDW54_RS06090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDW54_RS06095	COG3328	transposase activity
CDW54_RS06100	COG1522	sequence-specific DNA binding
CDW54_RS06130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDW54_RS06145	COG1461	Dihydroxyacetone kinase
CDW54_RS06150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDW54_RS06155	COG0416	fatty acid biosynthetic process
CDW54_RS06160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDW54_RS06170	COG4608	Belongs to the ABC transporter superfamily
CDW54_RS06175	COG0601	transmembrane transport
CDW54_RS06195	COG0571	ribonuclease III activity
CDW54_RS06200	COG1196	nuclear chromosome segregation
CDW54_RS06205	COG0561	phosphatase activity
CDW54_RS06210	COG0552	protein localization to endoplasmic reticulum
CDW54_RS06215	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDW54_RS06215	COG2918	glutathione biosynthetic process
CDW54_RS06225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDW54_RS06230	COG4605	iron ion homeostasis
CDW54_RS06235	COG4604	ABC transporter, ATP-binding protein
CDW54_RS06240	COG4607	ABC-type enterochelin transport system periplasmic component
CDW54_RS06280	COG3328	transposase activity
CDW54_RS06295	COG1380	Effector of murein hydrolase LrgA
CDW54_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
CDW54_RS06325	COG1268	BioY protein
CDW54_RS06330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDW54_RS06345	COG0561	phosphatase activity
CDW54_RS06355	COG1692	metallophosphoesterase
CDW54_RS06365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDW54_RS06375	COG0424	maF-like protein
CDW54_RS06380	COG1263	PTS System
CDW54_RS06380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS06385	COG2188	Transcriptional regulator
CDW54_RS06395	COG0632	four-way junction helicase activity
CDW54_RS06400	COG2255	four-way junction helicase activity
CDW54_RS06410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDW54_RS06420	COG1114	Component of the transport system for branched-chain amino acids
CDW54_RS06430	COG1113	amino acid transport
CDW54_RS06435	COG1126	abc transporter atp-binding protein
CDW54_RS06440	COG0765	amino acid transport
CDW54_RS06455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDW54_RS06460	COG0110	maltose O-acetyltransferase activity
CDW54_RS06465	COG1827	regulation of RNA biosynthetic process
CDW54_RS06475	COG0242	peptide deformylase activity
CDW54_RS06480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDW54_RS06485	COG1185	polyribonucleotide nucleotidyltransferase activity
CDW54_RS06495	COG3158	transport of potassium into the cell
CDW54_RS06500	COG1253	flavin adenine dinucleotide binding
CDW54_RS06505	COG0534	Mate efflux family protein
CDW54_RS06515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDW54_RS06520	COG1187	pseudouridine synthase activity
CDW54_RS06525	COG1011	Hydrolase
CDW54_RS06530	COG0572	uridine kinase
CDW54_RS06555	COG1671	Belongs to the UPF0178 family
CDW54_RS06565	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDW54_RS06570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDW54_RS06580	COG0736	holo-[acyl-carrier-protein] synthase activity
CDW54_RS06585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDW54_RS06590	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDW54_RS06600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDW54_RS06605	COG3321	synthase
CDW54_RS06605	COG0604	alcohol dehydrogenase
CDW54_RS06615	COG0531	amino acid
CDW54_RS06645	COG1174	glycine betaine transport
CDW54_RS06665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDW54_RS06680	COG0343	queuine tRNA-ribosyltransferase activity
CDW54_RS06685	COG1862	Preprotein translocase
CDW54_RS06695	COG1454	alcohol dehydrogenase
CDW54_RS06695	COG1012	belongs to the aldehyde dehydrogenase family
CDW54_RS06700	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDW54_RS06715	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDW54_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
CDW54_RS06725	COG1304	FMN binding
CDW54_RS06740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDW54_RS06745	COG1428	Deoxynucleoside kinase
CDW54_RS06760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDW54_RS06765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDW54_RS06770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDW54_RS06795	COG0824	Thioesterase
CDW54_RS06800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDW54_RS06820	COG1363	Peptidase, m42
CDW54_RS06825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDW54_RS06830	COG0589	response to stress
CDW54_RS06835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDW54_RS06840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDW54_RS06845	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDW54_RS06885	COG3328	transposase activity
CDW54_RS06900	COG0531	amino acid
CDW54_RS06905	COG0076	glutamate decarboxylase activity
CDW54_RS06920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDW54_RS06935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDW54_RS06965	COG3328	transposase activity
CDW54_RS06970	COG2261	transglycosylase associated protein
CDW54_RS06975	COG1764	response to oxidative stress
CDW54_RS07030	COG1368	sulfuric ester hydrolase activity
CDW54_RS07035	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CDW54_RS07045	COG0101	tRNA pseudouridine synthase activity
CDW54_RS07070	COG0667	Aldo Keto reductase
CDW54_RS07075	COG2186	Transcriptional regulator
CDW54_RS07080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS07085	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS07095	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDW54_RS07100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS07115	COG1063	alcohol dehydrogenase
CDW54_RS07135	COG4716	Myosin-crossreactive antigen
CDW54_RS07175	COG1113	amino acid transport
CDW54_RS07210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDW54_RS07220	COG3052	prosthetic group binding
CDW54_RS07290	COG1051	belongs to the nudix hydrolase family
CDW54_RS07295	COG1846	Transcriptional regulator
CDW54_RS07320	COG2252	PERMEase
CDW54_RS07325	COG0366	Alpha amylase catalytic
CDW54_RS07330	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS07340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS07340	COG2190	(PTS) system
CDW54_RS07340	COG1263	PTS System
CDW54_RS07345	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS07365	COG1902	pentaerythritol trinitrate reductase activity
CDW54_RS07375	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDW54_RS07385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDW54_RS07390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDW54_RS07395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDW54_RS07400	COG1193	negative regulation of DNA recombination
CDW54_RS07405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDW54_RS07420	COG1937	Protein conserved in bacteria
CDW54_RS07425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDW54_RS07430	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDW54_RS07435	COG3973	AAA domain
CDW54_RS07445	COG3328	transposase activity
CDW54_RS07470	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CDW54_RS07475	COG2376	Dihydroxyacetone kinase
CDW54_RS07480	COG1461	Dihydroxyacetone kinase
CDW54_RS07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDW54_RS07505	COG1131	(ABC) transporter
CDW54_RS07510	COG1309	transcriptional regulator
CDW54_RS07530	COG0531	amino acid
CDW54_RS07535	COG1757	Na H antiporter
CDW54_RS07540	COG1609	Transcriptional regulator
CDW54_RS07550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS07560	COG1263	PTS System
CDW54_RS07560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS07560	COG2190	(PTS) system
CDW54_RS07590	COG3479	Phenolic acid decarboxylase
CDW54_RS07595	COG1695	Transcriptional regulator
CDW54_RS07605	COG2814	Major facilitator Superfamily
CDW54_RS07635	COG0163	prenyltransferase activity
CDW54_RS07640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDW54_RS07650	COG1136	(ABC) transporter
CDW54_RS07650	COG1136	(ABC) transporter
CDW54_RS07650	COG0577	efflux transmembrane transporter activity
CDW54_RS07650	COG0577	efflux transmembrane transporter activity
CDW54_RS07670	COG1811	Na channel or pump
CDW54_RS07705	COG1136	(ABC) transporter
CDW54_RS07720	COG3942	CHAP domain
CDW54_RS07720	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDW54_RS07730	COG3328	transposase activity
CDW54_RS07735	COG1263	PTS System
CDW54_RS07735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS07735	COG2190	(PTS) system
CDW54_RS07740	COG1869	D-ribose catabolic process
CDW54_RS07750	COG1609	Transcriptional regulator
CDW54_RS07770	COG0366	Alpha amylase catalytic
CDW54_RS07780	COG0628	permease
CDW54_RS07785	COG3443	Belongs to the bacterial solute-binding protein 9 family
CDW54_RS07785	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDW54_RS07805	COG3328	transposase activity
CDW54_RS07815	COG1428	Deoxynucleoside kinase
CDW54_RS07830	COG0210	DNA helicase
CDW54_RS07835	COG1393	Belongs to the ArsC family
CDW54_RS07840	COG1393	Belongs to the ArsC family
CDW54_RS07865	COG0386	Belongs to the glutathione peroxidase family
CDW54_RS07870	COG1854	S-ribosylhomocysteine lyase activity
CDW54_RS07875	COG0626	cystathionine gamma-synthase activity
CDW54_RS07880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDW54_RS07895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDW54_RS07900	COG0019	diaminopimelate decarboxylase activity
CDW54_RS07905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDW54_RS07915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDW54_RS07920	COG2171	N-acyltransferase activity
CDW54_RS07925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDW54_RS07930	COG0527	aspartate kinase activity
CDW54_RS07935	COG1473	amidohydrolase
CDW54_RS07940	COG0436	Aminotransferase
CDW54_RS07945	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDW54_RS07955	COG2323	membrane
CDW54_RS07965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDW54_RS07970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDW54_RS07985	COG2207	Transcriptional regulator
CDW54_RS07990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDW54_RS08000	COG1113	amino acid transport
CDW54_RS08005	COG1121	(ABC) transporter
CDW54_RS08010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDW54_RS08025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDW54_RS08030	COG1652	LysM domain
CDW54_RS08030	COG2823	Periplasmic or secreted lipoprotein
CDW54_RS08040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDW54_RS08045	COG0477	Major facilitator Superfamily
CDW54_RS08055	COG1438	arginine binding
CDW54_RS08070	COG1764	response to oxidative stress
CDW54_RS08075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDW54_RS08080	COG1335	isochorismatase
CDW54_RS08090	COG2135	peptidase activity
CDW54_RS08140	COG0745	RESPONSE REGULATOR receiver
CDW54_RS08145	COG2205	protein histidine kinase activity
CDW54_RS08150	COG4975	Glucose uptake
CDW54_RS08155	COG0531	amino acid
CDW54_RS08160	COG3853	Toxic anion resistance protein (TelA)
CDW54_RS08180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDW54_RS08185	COG1335	isochorismatase
CDW54_RS08200	COG3590	peptidase
CDW54_RS08210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDW54_RS08215	COG1104	cysteine desulfurase activity
CDW54_RS08235	COG0482	sulfurtransferase activity
CDW54_RS08245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDW54_RS08250	COG2814	Major facilitator Superfamily
CDW54_RS08270	COG0463	Glycosyl transferase, family 2
CDW54_RS08275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDW54_RS08280	COG2855	membrane
CDW54_RS08295	COG0583	DNA-binding transcription factor activity
CDW54_RS08305	COG0772	Belongs to the SEDS family
CDW54_RS08310	COG1393	Belongs to the ArsC family
CDW54_RS08315	COG0509	glycine decarboxylation via glycine cleavage system
CDW54_RS08320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDW54_RS08325	COG2011	ABC-type metal ion transport system permease component
CDW54_RS08330	COG1464	Belongs to the NlpA lipoprotein family
CDW54_RS08340	COG0719	Fe-S assembly protein
CDW54_RS08345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDW54_RS08355	COG0719	Fe-S assembly protein
CDW54_RS08435	COG4695	Portal protein
CDW54_RS08650	COG0662	Cupin 2, conserved barrel domain protein
CDW54_RS08655	COG4619	ABC transporter
CDW54_RS08660	COG0390	transport system, permease component
CDW54_RS08680	COG2801	Transposase and inactivated derivatives
CDW54_RS08705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDW54_RS08715	COG1597	lipid kinase activity
CDW54_RS08760	COG3764	Sortase (surface protein transpeptidase)
CDW54_RS08770	COG1263	PTS System
CDW54_RS08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS08770	COG2190	(PTS) system
CDW54_RS08775	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS08780	COG2188	Transcriptional regulator
CDW54_RS08805	COG1611	Belongs to the LOG family
CDW54_RS08815	COG1428	Deoxynucleoside kinase
CDW54_RS08830	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS08840	COG1368	sulfuric ester hydrolase activity
CDW54_RS08850	COG0105	UTP biosynthetic process
CDW54_RS08855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDW54_RS08860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS08870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDW54_RS08875	COG2011	ABC-type metal ion transport system permease component
CDW54_RS08880	COG1464	Belongs to the NlpA lipoprotein family
CDW54_RS08890	COG1757	Na H antiporter
CDW54_RS08905	COG1113	amino acid transport
CDW54_RS08915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDW54_RS08920	COG1929	Belongs to the glycerate kinase type-1 family
CDW54_RS08925	COG0488	(ABC) transporter
CDW54_RS08940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDW54_RS08945	COG1263	PTS System
CDW54_RS08945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS08960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CDW54_RS08965	COG1131	(ABC) transporter
CDW54_RS08975	COG3328	transposase activity
CDW54_RS08990	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDW54_RS09005	COG0346	lactoylglutathione lyase activity
CDW54_RS09045	COG0561	phosphatase activity
CDW54_RS09050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDW54_RS09055	COG0280	phosphate acetyltransferase
CDW54_RS09060	COG0802	atpase or kinase
CDW54_RS09065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDW54_RS09085	COG0708	Exodeoxyribonuclease III
CDW54_RS09095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDW54_RS09130	COG1053	succinate dehydrogenase
CDW54_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
CDW54_RS09135	COG0604	alcohol dehydrogenase
CDW54_RS09135	COG3321	synthase
CDW54_RS09140	COG0702	epimerase
CDW54_RS09145	COG4684	Psort location CytoplasmicMembrane, score
CDW54_RS09150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDW54_RS09155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDW54_RS09160	COG0604	alcohol dehydrogenase
CDW54_RS09170	COG3842	ATPase activity
CDW54_RS09175	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDW54_RS09180	COG1177	transmembrane transport
CDW54_RS09185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDW54_RS09195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDW54_RS09200	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDW54_RS09210	COG0488	(ABC) transporter
CDW54_RS09215	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDW54_RS09225	COG0701	Predicted permease
CDW54_RS09230	COG3689	TIGRFAM TIGR03943 family protein
CDW54_RS09260	COG4472	Bacterial protein of unknown function (DUF965)
CDW54_RS09265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDW54_RS09270	COG3906	Belongs to the UPF0473 family
CDW54_RS09290	COG0281	malic enzyme
CDW54_RS09300	COG1304	FMN binding
CDW54_RS09345	COG1136	(ABC) transporter
CDW54_RS09370	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDW54_RS09385	COG1193	negative regulation of DNA recombination
CDW54_RS09390	COG3118	belongs to the thioredoxin family
CDW54_RS09395	COG0322	excinuclease ABC activity
CDW54_RS09400	COG4152	abc transporter atp-binding protein
CDW54_RS09410	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CDW54_RS09425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDW54_RS09435	COG1269	ATP hydrolysis coupled proton transport
CDW54_RS09440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDW54_RS09445	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CDW54_RS09450	COG1527	subunit (C
CDW54_RS09455	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
CDW54_RS09460	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CDW54_RS09465	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CDW54_RS09470	COG1394	ATPase activity, coupled to movement of substances
CDW54_RS09475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDW54_RS09480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDW54_RS09485	COG2423	ornithine cyclodeaminase activity
CDW54_RS09495	COG0346	lactoylglutathione lyase activity
CDW54_RS09500	COG0494	nUDIX hydrolase
CDW54_RS09505	COG0561	phosphatase activity
CDW54_RS09510	COG1078	dGTPase activity
CDW54_RS09515	COG0095	Lipoate-protein ligase
CDW54_RS09535	COG1595	DNA-templated transcription, initiation
CDW54_RS09555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDW54_RS09560	COG2390	Transcriptional regulator
CDW54_RS09570	COG0126	phosphoglycerate kinase activity
CDW54_RS09575	COG0149	triose-phosphate isomerase activity
CDW54_RS09585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDW54_RS09595	COG1957	nucleoside hydrolase
CDW54_RS09605	COG2388	GCN5-related N-acetyl-transferase
CDW54_RS09610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDW54_RS09620	COG0557	exoribonuclease II activity
CDW54_RS09625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDW54_RS09630	COG0356	it plays a direct role in the translocation of protons across the membrane
CDW54_RS09635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDW54_RS09640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDW54_RS09645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDW54_RS09650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDW54_RS09655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDW54_RS09660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDW54_RS09665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDW54_RS09675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDW54_RS09695	COG1940	carbohydrate kinase activity
CDW54_RS09715	COG2188	Transcriptional regulator
CDW54_RS09720	COG1739	Uncharacterized protein family UPF0029
CDW54_RS09730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDW54_RS09735	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CDW54_RS09750	COG0653	protein targeting
CDW54_RS09760	COG2884	Cell division ATP-binding protein ftsE
CDW54_RS09765	COG2177	Part of the ABC transporter FtsEX involved in
CDW54_RS09770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDW54_RS09775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDW54_RS09780	COG0573	inorganic phosphate transmembrane transporter activity
CDW54_RS09785	COG0581	inorganic phosphate transmembrane transporter activity
CDW54_RS09790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDW54_RS09795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDW54_RS09800	COG0704	Plays a role in the regulation of phosphate uptake
CDW54_RS09835	COG1950	PFAM Membrane protein of
CDW54_RS09840	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDW54_RS09845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDW54_RS09850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDW54_RS09855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDW54_RS09865	COG4980	gas vesicle protein
CDW54_RS09870	COG0006	proline dipeptidase activity
CDW54_RS09875	COG1609	Transcriptional regulator
CDW54_RS09890	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDW54_RS09900	COG1914	H( )-stimulated, divalent metal cation uptake system
CDW54_RS09905	COG3763	UPF0154 protein
CDW54_RS09910	COG1132	(ABC) transporter
CDW54_RS09915	COG1132	(ABC) transporter
CDW54_RS09920	COG3711	transcriptional antiterminator
CDW54_RS09925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDW54_RS09925	COG2190	(PTS) system
CDW54_RS09925	COG1263	PTS System
CDW54_RS09930	COG1737	Transcriptional regulator
CDW54_RS09940	COG1486	melibiose metabolic process
CDW54_RS09945	COG2723	6-phospho-beta-galactosidase activity
CDW54_RS09950	COG0492	ferredoxin-NADP+ reductase activity
CDW54_RS09955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDW54_RS09960	COG0640	Transcriptional regulator
CDW54_RS09965	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDW54_RS09970	COG0735	belongs to the Fur family
CDW54_RS09975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDW54_RS09980	COG1610	YqeY-like protein
CDW54_RS09985	COG1114	Component of the transport system for branched-chain amino acids
CDW54_RS09990	COG1702	phosphate starvation-inducible protein PhoH
CDW54_RS10000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDW54_RS10005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDW54_RS10010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDW54_RS10015	COG1381	Involved in DNA repair and RecF pathway recombination
CDW54_RS10020	COG0752	glycyl-tRNA synthetase alpha subunit
CDW54_RS10025	COG0751	glycine-tRNA ligase activity
CDW54_RS10035	COG1316	TRANSCRIPTIONal
CDW54_RS10040	COG3944	biosynthesis protein
CDW54_RS10045	COG0489	protein tyrosine kinase activity
CDW54_RS10050	COG4464	protein tyrosine phosphatase activity
CDW54_RS10055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDW54_RS10060	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CDW54_RS10095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDW54_RS10115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDW54_RS10115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS10115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS10125	COG0706	membrane insertase activity
CDW54_RS10135	COG1254	Belongs to the acylphosphatase family
CDW54_RS10140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDW54_RS10160	COG0038	chloride channel
CDW54_RS10170	COG1686	Belongs to the peptidase S11 family
CDW54_RS10185	COG1278	Cold shock
CDW54_RS10190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDW54_RS10190	COG1199	ATP-dependent helicase activity
CDW54_RS10200	COG0436	Aminotransferase
CDW54_RS10205	COG0017	Asparaginyl-tRNA synthetase
CDW54_RS10235	COG2217	Heavy metal translocating P-type atpase
CDW54_RS10240	COG0531	amino acid
CDW54_RS10255	COG3682	Transcriptional regulator
CDW54_RS10260	COG2608	mercury ion transmembrane transporter activity
CDW54_RS10265	COG2217	Heavy metal translocating P-type atpase
CDW54_RS10270	COG2217	Heavy metal translocating P-type atpase
CDW54_RS10285	COG0714	Associated with various cellular activities
CDW54_RS10320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CDW54_RS10325	COG3328	transposase activity
CDW54_RS10345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDW54_RS10350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDW54_RS10355	COG5002	protein histidine kinase activity
CDW54_RS10360	COG0745	RESPONSE REGULATOR receiver
CDW54_RS10370	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CDW54_RS10375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDW54_RS10380	COG0519	Catalyzes the synthesis of GMP from XMP
CDW54_RS10385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDW54_RS10390	COG0431	NADPH-dependent FMN reductase
CDW54_RS10395	COG0228	four-way junction DNA binding
CDW54_RS10400	COG1837	Belongs to the UPF0109 family
CDW54_RS10410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDW54_RS10415	COG0336	Belongs to the RNA methyltransferase TrmD family
CDW54_RS10420	COG0335	large ribosomal subunit rRNA binding
CDW54_RS10450	COG1175	transmembrane transport
CDW54_RS10455	COG0395	ABC-type sugar transport system, permease component
CDW54_RS10465	COG0028	Belongs to the TPP enzyme family
CDW54_RS10470	COG3527	Alpha-acetolactate decarboxylase
CDW54_RS10475	COG1956	GAF domain-containing protein
CDW54_RS10535	COG0745	RESPONSE REGULATOR receiver
CDW54_RS10540	COG5002	protein histidine kinase activity
CDW54_RS10540	COG3850	Histidine kinase
CDW54_RS10560	COG1368	sulfuric ester hydrolase activity
CDW54_RS10565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDW54_RS10570	COG0710	3-dehydroquinate dehydratase activity
CDW54_RS10575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDW54_RS10580	COG2081	HI0933 family
CDW54_RS10585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDW54_RS10590	COG0166	Belongs to the GPI family
CDW54_RS10610	COG0584	glycerophosphoryl diester phosphodiesterase
CDW54_RS10620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDW54_RS10640	COG1309	transcriptional regulator
CDW54_RS10655	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CDW54_RS10660	COG0367	asparagine synthase
CDW54_RS10665	COG4876	unkown
CDW54_RS10670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDW54_RS10685	COG1120	ATPase activity
CDW54_RS10690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDW54_RS10695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDW54_RS10700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDW54_RS10715	COG1940	carbohydrate kinase activity
CDW54_RS10720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDW54_RS10725	COG3189	MarR family transcriptional regulator
CDW54_RS10740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDW54_RS10745	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CDW54_RS10750	COG1609	Transcriptional regulator
CDW54_RS10755	COG1214	PFAM Peptidase M22, glycoprotease
CDW54_RS10765	COG0456	acetyltransferase
CDW54_RS10770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDW54_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDW54_RS10780	COG2235	arginine
CDW54_RS10795	COG0018	arginyl-trna synthetase
CDW54_RS10815	COG1438	arginine binding
CDW54_RS10820	COG0052	Belongs to the universal ribosomal protein uS2 family
CDW54_RS10825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDW54_RS10830	COG0528	UMP kinase activity
CDW54_RS10835	COG0233	cytoplasmic translational termination
CDW54_RS10840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDW54_RS10845	COG4589	Belongs to the CDS family
CDW54_RS10850	COG0750	zinc metalloprotease
CDW54_RS10855	COG0442	prolyl-tRNA aminoacylation
CDW54_RS10860	COG2176	DNA-directed DNA polymerase activity
CDW54_RS10865	COG0779	Required for maturation of 30S ribosomal subunits
CDW54_RS10870	COG0195	Participates in both transcription termination and antitermination
CDW54_RS10875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDW54_RS10890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDW54_RS10895	COG1175	transmembrane transport
CDW54_RS10900	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDW54_RS10905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDW54_RS10910	COG0196	riboflavin kinase activity
CDW54_RS10920	COG4975	Glucose uptake
CDW54_RS10930	COG5646	InterPro IPR014922
CDW54_RS10940	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDW54_RS10950	COG0693	protein deglycase activity
CDW54_RS10975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDW54_RS10980	COG1420	regulation of RNA biosynthetic process
CDW54_RS10985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDW54_RS10990	COG0443	Heat shock 70 kDa protein
CDW54_RS10995	COG0484	heat shock protein binding
CDW54_RS11000	COG1126	abc transporter atp-binding protein
CDW54_RS11005	COG0765	amino acid transport
CDW54_RS11010	COG0556	nucleotide-excision repair
CDW54_RS11015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDW54_RS11030	COG1660	Displays ATPase and GTPase activities
CDW54_RS11035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDW54_RS11040	COG1481	regulation of sporulation
CDW54_RS11080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDW54_RS11105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDW54_RS11125	COG1714	RDD family
CDW54_RS11135	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDW54_RS11140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDW54_RS11145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDW54_RS11160	COG1349	DNA-binding transcription factor activity
CDW54_RS11165	COG1105	Belongs to the carbohydrate kinase PfkB family
CDW54_RS11170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDW54_RS11170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDW54_RS11170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDW54_RS11180	COG0210	DNA helicase
CDW54_RS11185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDW54_RS11190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDW54_RS11195	COG0154	amidase activity
CDW54_RS11200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDW54_RS11205	COG1597	lipid kinase activity
CDW54_RS11210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDW54_RS11245	COG1609	Transcriptional regulator
CDW54_RS11260	COG3250	beta-galactosidase activity
CDW54_RS11270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDW54_RS11280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDW54_RS11285	COG0287	Prephenate dehydrogenase
CDW54_RS11290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDW54_RS11295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDW54_RS11300	COG0077	Prephenate dehydratase
CDW54_RS11305	COG2972	Histidine kinase
CDW54_RS11310	COG4753	response regulator
CDW54_RS11310	COG2207	Transcriptional regulator
CDW54_RS11355	COG0588	phosphoglycerate mutase activity
CDW54_RS11360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDW54_RS11380	COG1054	Belongs to the UPF0176 family
CDW54_RS11390	COG2183	response to ionizing radiation
CDW54_RS11395	COG3091	SprT-like family
CDW54_RS11400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CDW54_RS11405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDW54_RS11420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDW54_RS11420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDW54_RS11425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDW54_RS11430	COG0237	dephospho-CoA kinase activity
CDW54_RS11440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDW54_RS11450	COG1484	DNA-dependent DNA replication
CDW54_RS11460	COG2384	SAM-dependent methyltransferase
CDW54_RS11465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDW54_RS11470	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDW54_RS11475	COG1597	lipid kinase activity
CDW54_RS11510	COG0542	response to heat
CDW54_RS11530	COG0481	GTPase activity
CDW54_RS11555	COG3328	transposase activity
CDW54_RS11565	COG1278	Cold shock
CDW54_RS11570	COG0640	Transcriptional regulator
CDW54_RS11645	COG3730	PTS system glucitol sorbitol-specific
CDW54_RS11650	COG3732	PTS system glucitol sorbitol-specific
CDW54_RS11665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDW54_RS11700	COG1737	Transcriptional regulator
CDW54_RS11700	COG0837	glucose binding
CDW54_RS11720	COG1278	Cold shock
CDW54_RS11730	COG1476	TRANSCRIPTIONal
CDW54_RS11755	COG0561	phosphatase activity
CDW54_RS11760	COG1442	glycosyl transferase family 8
CDW54_RS11765	COG1442	glycosyl transferase family 8
CDW54_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
CDW54_RS11800	COG2261	transglycosylase associated protein
CDW54_RS11815	COG3655	Transcriptional regulator
CDW54_RS11840	COG2261	transglycosylase associated protein
CDW54_RS11850	COG0004	ammonium transporteR
CDW54_RS11855	COG0531	amino acid
CDW54_RS11870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDW54_RS11885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDW54_RS11905	COG0768	penicillin binding
CDW54_RS11940	COG0246	Mannitol dehydrogenase
CDW54_RS11945	COG1312	Catalyzes the dehydration of D-mannonate
CDW54_RS11960	COG0628	permease
CDW54_RS11965	COG1846	Transcriptional regulator
CDW54_RS11970	COG1764	response to oxidative stress
CDW54_RS11980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDW54_RS11985	COG0366	Alpha amylase catalytic
CDW54_RS11990	COG2182	Extracellular solute-binding protein
CDW54_RS11995	COG1175	transmembrane transport
CDW54_RS12000	COG3833	ABC-type maltose transport systems, permease component
CDW54_RS12010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDW54_RS12020	COG0167	dihydroorotate dehydrogenase activity
CDW54_RS12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDW54_RS12035	COG0765	amino acid transport
CDW54_RS12055	COG0194	GDP metabolic process
CDW54_RS12060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDW54_RS12115	COG2244	polysaccharide biosynthetic process
CDW54_RS12120	COG1307	EDD domain protein, DegV family
CDW54_RS12135	COG0366	Alpha amylase catalytic
CDW54_RS12140	COG4475	Protein of unknown function (DUF436)
CDW54_RS12150	COG0351	phosphomethylpyrimidine kinase
CDW54_RS12175	COG5002	protein histidine kinase activity
CDW54_RS12180	COG0745	RESPONSE REGULATOR receiver
CDW54_RS12215	COG0673	inositol 2-dehydrogenase activity
CDW54_RS12225	COG3711	transcriptional antiterminator
CDW54_RS12235	COG3037	sugar-specific permease SgaT UlaA
CDW54_RS12260	COG0039	L-malate dehydrogenase activity
CDW54_RS12295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDW54_RS12305	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDW54_RS12320	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CDW54_RS12355	COG0284	orotidine-5'-phosphate decarboxylase activity
CDW54_RS12365	COG0543	2 iron, 2 sulfur cluster binding
CDW54_RS12370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDW54_RS12375	COG0505	Belongs to the CarA family
CDW54_RS12380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDW54_RS12385	COG0540	Belongs to the ATCase OTCase family
CDW54_RS12390	COG2233	PERMEase
CDW54_RS12400	COG0564	pseudouridine synthase activity
CDW54_RS12405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDW54_RS12420	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDW54_RS12425	COG1278	Cold shock
CDW54_RS12435	COG0328	RNA-DNA hybrid ribonuclease activity
CDW54_RS12445	COG4684	Psort location CytoplasmicMembrane, score
CDW54_RS12450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDW54_RS12460	COG2153	protein acetylation
CDW54_RS12465	COG0513	Belongs to the DEAD box helicase family
CDW54_RS12480	COG0531	amino acid
CDW54_RS12485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDW54_RS12490	COG0156	8-amino-7-oxononanoate synthase activity
CDW54_RS12505	COG1418	mRNA catabolic process
CDW54_RS12510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CDW54_RS12515	COG0116	Belongs to the methyltransferase superfamily
CDW54_RS12525	COG3599	regulation of cell shape
CDW54_RS12530	COG4474	Belongs to the UPF0398 family
CDW54_RS12535	COG3331	DNA recombination
CDW54_RS12540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDW54_RS12550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDW54_RS12555	COG3935	DnaD domain protein
CDW54_RS12565	COG1846	Transcriptional regulator
CDW54_RS12575	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDW54_RS12580	COG0735	belongs to the Fur family
CDW54_RS12585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDW54_RS12590	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDW54_RS12590	COG1388	LysM domain
CDW54_RS12605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDW54_RS12615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDW54_RS12620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDW54_RS12620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDW54_RS12625	COG5416	Lipopolysaccharide assembly protein A domain
CDW54_RS12630	COG0300	oxidoreductase activity
CDW54_RS12635	COG1234	tRNA 3'-trailer cleavage
CDW54_RS12645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDW54_RS12670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDW54_RS12675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDW54_RS12680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDW54_RS12690	COG0668	transmembrane transport
CDW54_RS12695	COG0517	IMP dehydrogenase activity
CDW54_RS12705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDW54_RS12710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis